name: AJUBA binds centrosome-associated AURKA (Gallus gallus)


name: myricetin + S-adenosyl-L-methionine => 3-O-methylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: ATP + holo-[peptidyl-carrier protein] + L-alanine => AMP + diphosphate + L-alanyl-[peptidyl-carrier protein]


name: [sulfur carrier]-SH + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + S-adenosyl-L-methionine => [sulfur carrier]-H + H(+) + L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + S-adenosyl-L-homocysteine


name: 4-hydroxybenzoate + ATP + CoA = 4-hydroxybenzoyl-CoA + AMP + diphosphate


name: L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine => H(+) + N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O => 2-(9Z-octadecenoyl)-glycerol + H(+) + octadecanoate


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Bos taurus)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Sus scrofa)


name: H(+) + NADPH + O2 + resorcinol = benzene-1,2,4-triol + H2O + NADP(+)


name: anthraniloyl-CoA + methanol => CoA + O-methyl anthranilate


name: HTR1A binds HTR1A agonists (Rattus norvegicus)


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: H2O + N(6)-acetyl-L-lysyl-[protein] + O2 => (S)-2-amino-6-oxohexanoyl-[protein] + acetamide + H2O2


name: N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: a monoamide of a dicarboxylate + H2O <=> a dicarboxylate + NH4(+)


name: (2E,6E)-farnesyl diphosphate <=> (3S)-(+)-asterisca-2(9),6-diene + diphosphate


name: glycine + H(+) + tRNA(Ala) => glycyl-tRNA(Ala) + H2O


name: PP6-PPP6R3 dephosphorylates TERF2 (Canis familiaris)


name: THG1L transfers GMP to 5' end of tRNA(His) (Homo sapiens)


name: Phosphorylated MAPKs phosphorylate ATF-2 (Sus scrofa)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Gallus gallus)


name: [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose <=> alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Homo sapiens)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: 3,5-dibromo-4-hydroxybenzoate + NH4(+) => 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Gallus gallus)


name: HCCS inserts heme into cytochrome c (Homo sapiens)


name: 2 glutathione + NADP(+) = glutathione disulfide + H(+) + NADPH


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Canis familiaris)


name: arsenite + H2O + 2 oxidized [azurin] = arsenate + 3 H(+) + 2 reduced [azurin]


name: (3Z)-2-oxo-4-carboxy-3-hexenedioate + H2O = (2S)-2-hydroxy-4-oxobutane-1,2,4-tricarboxylate


name: (2E)-hexadecenal + phosphoethanolamine => sphing-4-enine 1-phosphate


name: PSAP(195-273) forms a dimer (Dictyostelium discoideum)


name: D-sorbitol 6-phosphate + H2O = D-sorbitol + phosphate


name: MLNR (GPR38) is a receptor for motilin (Bos taurus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Danio rerio)


name: biotin(out) + 2 Na(+)(out) => biotin(in) + 2 Na(+)(in)


name: Release of platelet cytosolic components (Schizosaccharomyces pombe)


name: a ganglioside Ac-O-7-GD1a (d18:1(4E)) => a ganglioside Ac-O-8-GD1a (d18:1(4E))


name: a 3'-end 2',3'-cyclophospho-uridine-RNA + adenosine => a 3'-end uridylyl-adenosine-RNA


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Gallus gallus)


name: (1R,4S)-isodihydrocarvone + H(+) + NADH => (1R,2R,4S)-isodihydrocarveol + NAD(+)


name: Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 (Bos taurus)


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Caenorhabditis elegans)


name: Fe(III)-heme b-[protein] + nitrate => Fe(II)-heme b-[protein] + nitric oxide + O2


name: 2'-O-methyllicodione + H(+) + S-adenosyl-L-homocysteine => licodione + S-adenosyl-L-methionine


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Bos taurus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: BIL:ALB scavenges O2.- (Xenopus tropicalis)


name: p-PKR dimer phosphorylates CDK1 (Xenopus tropicalis)


name: chenodeoxycholate + taurine => H2O + taurochenodeoxycholate


name: 2-oxoglutarate + nonyl sufate + O2 => CO2 + H(+) + nonanal + succinate + sulfate


name: Abortive termination of early transcription elongation by DSIF:NELF (Xenopus tropicalis)


name: IL12RB1:TYK2 binds IL12RB2:JAK2 (Canis familiaris)


name: calmodulin-activated 3',5'-cyclic-AMP phosphodiesterase activity


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Mus musculus)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Caenorhabditis elegans)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Xenopus tropicalis)


name: 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + CO2 + CoA => (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + H(+) + malonyl-CoA


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Dictyostelium discoideum)


name: ARBB recruits GPCRs into clathrin-coated pits (Mus musculus)


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate <=> 2-oxoglutarate + GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: ARSC hydrolyzes steroid sulfates (Rattus norvegicus)


name: glycyl-L-leucine(in) + H(+)(in) => glycyl-L-leucine(out) + H(+)(out)


name: H2O + phenguignardate => 2 3-phenylpyruvate + H(+)


name: H2O2 + hexadecanal => hexadecan-1-ol + O2


name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Sus scrofa)


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Gallus gallus)


name: (+)-delta-cadinol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Mus musculus)


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Rattus norvegicus)


name: SUMOylation of TOP2A with SUMO1 (Xenopus tropicalis)


name: H(+)(out) + L-leucine(in) <=> H(+)(in) + L-leucine(out)


name: ROCK activation by RHO (Canis familiaris)


name: Tenascins C, R, (X, N) bind fibronectin matrix (Rattus norvegicus)


name: The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Caenorhabditis elegans)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Rattus norvegicus)


name: 2 H(+) + 2 malonyl-CoA + octadecanoyl-CoA = 4-hydroxy-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA


name: SH mRNA is translated into protein SHt (Homo sapiens)


name: 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine => 8,12-diethyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine


name: Phosphorylation of COP1 at Ser-387  by ATM (Canis familiaris)


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Mus musculus)


name: (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H(+) + NADPH => (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: cis-stilbene oxide + H2O <=> (1R,2R)-hydrobenzoin


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Caenorhabditis elegans)


name: MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Danio rerio)


name: Binding of the MCC complex to the APC/C complex (Rattus norvegicus)


name: menaquinol-8 + 2 O2 => 2 H(+) + menaquinone-8 + 2 superoxide


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Xenopus tropicalis)


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Rattus norvegicus)


name: 17-O-acetylajmaline + H2O = acetate + ajmaline + H(+)


name: Addition of GlcNAc to position 5 by MGAT5 (Sus scrofa)


name: PDE5A dimer binds PDE5A inhibitors (Homo sapiens)


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine => 2 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine


name: RNF152 polyubiquitinates RRAGA (Mus musculus)


name: 5,6-dihydrouracil + O2 <=> H2O2 + uracil


name: Autophosphorylation of BTK/ITK (Canis familiaris)


name: UMPS dimer decarboxylates OMP to UMP (Mus musculus)


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Drosophila melanogaster)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Mus musculus)


name: 2-exo-hydroxy-1,4-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 1,4-cineole + O2 + reduced [NADPH--hemoprotein reductase]


name: WDR5 binds Me2sR3-replicative histone H3 (Canis familiaris)


name: Formation of the CTF18-RFC(7s) complex (Mus musculus)


name: 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H(+) = deacetylpyripyropene E


name: CDP-ethanolamine + diphosphate => CTP + H(+) + phosphoethanolamine


name: Frataxin transfers Fe2+ to ACO2 (Rattus norvegicus)


name: N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: 5-HT2 receptor can bind serotonin (Drosophila melanogaster)


name: The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering (Homo sapiens)


name: PTN and MDK bind to PTPRZ (Mus musculus)


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Xenopus tropicalis)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Activation of Rac1 by pVav1 (Xenopus tropicalis)


name: 1-eicosanoylglycerol + H2O <=> eicosanoate + glycerol + H(+)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Xenopus tropicalis)


name: Hemes:LY96 activates TLR4 (Canis familiaris)


name: GMPS dimer transforms 6TXMP to 6TGMP (Sus scrofa)


name: Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Bos taurus)


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: (S)-tetrahydropalmatine + S-adenosyl-L-methionine <=> (S)-cis-N-methyltetrahydropalmatine + S-adenosyl-L-homocysteine


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Bos taurus)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Xenopus tropicalis)


name: Activated FGFR2:pFRS binds GRB2:SOS1 (Rattus norvegicus)


name: 12,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 12-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: PEX19:class I PMP binds PEX3 (Mus musculus)


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Homo sapiens)


name: S-adenosyl-L-methionine + scutellarein 7-methyl ether <=> H(+) + ladanein + S-adenosyl-L-homocysteine


name: 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)


name: MTMR4 binds phosphorylated SMAD2/3 (Bos taurus)


name: (6Z)-hexadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + hexadecanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 => N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-glycine


name: ERKs are inactivated by protein phosphatase 2A (Danio rerio)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH <=> (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: an alkanesulfonate + FMNH2 + O2 => an aldehyde + FMN + 2 H(+) + H2O + sulfite


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Dictyostelium discoideum)


name: Association of Emi1 with Cdc20 (Canis familiaris)


name: D-galactonate + H(+) => D-galactono-1,4-lactone + H2O


name: (S)-2-hydroxyglutarate + GDP-D-glycero-4-keto-alpha-D-lyxo-heptose => 2-oxoglutarate + GDP-D-glycero-alpha-D-manno-heptose


name: GBF1 stimulates nucleotide exchange on ARF4 (Homo sapiens)


name: PI3-kinase binds to the active receptor (Danio rerio)


name: androsterone + NAD(+) = 5alpha-androstan-3,17-dione + H(+) + NADH


name: germacra-1(10),4,11(13)-trien-12-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> germacra-1(10),4,11(13)-trien-12-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Xenopus tropicalis)


name: cytidine(out) + 2 Na(+)(out) <=> cytidine(in) + 2 Na(+)(in)


name: Translocation of YAP1 to the nucleus (Mus musculus)


name: MAOB:FAD oxidatively deaminates of PEA (Sus scrofa)


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Rattus norvegicus)


name: H2O + L-2-aminopentanoate + NAD(+) <=> 2-oxopentanoate + H(+) + NADH + NH4(+)


name: L-alanine(in) + L-glutamine(out) + Na(+)(in) => L-alanine(out) + L-glutamine(in) + Na(+)(out)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Caenorhabditis elegans)


name: SPRED dimer binds NF1 (Dictyostelium discoideum)


name: HDAC1:2-containing complex deacetylate histones (Schizosaccharomyces pombe)


name: 2 H(+)(in) + H2 + ubiquinone-8 <=> 2 H(+)(out) + ubiquinol-8


name: 3-deoxyglucosone + H2O + NAD(+) => 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH


name: GEFs activate RhoA,B,C (Canis familiaris)


name: Degradation of ubiquitinated SKI/SKIL (Drosophila melanogaster)


name: SARS-CoV-1 3a binds the lysosomal membrane (Homo sapiens)


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: HuR binds mRNAs in the nucleus (Bos taurus)


name: 2-oxoglutarate + D-lysine <=> 6-amino-2-oxohexanoate + D-glutamate


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Rattus norvegicus)


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Sus scrofa)


name: 24-methylenecholesterol + UDP-alpha-D-glucose => 24-methylene cholesteryl beta-D-glucoside + H(+) + UDP


name: dec-9-enoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = dec-9-ynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Syndecans 1, 2 & 4 bind VTN (Xenopus tropicalis)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1,2-dihexadecanoyl-sn-glycerol + H(+) + phosphoethanolamine


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM3 (d18:1(4E)) + CMP + H(+)


name: Spermidine  => N-acetylated spermidine (Saccharomyces cerevisiae)


name: (3S)-3-hydroxy-D-aspartate <=> glycine + glyoxylate


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Mus musculus)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Danio rerio)


name: (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + 2-oxoglutarate + AH2 + H(+) + O2 = (2S)-5,5-dimethylpiperidine-2-carboxylate + A + 2 CO2 + H2O + succinate


name: p-Y694-STAT5A, p-STAT5B dimerizes (Xenopus tropicalis)


name: 2 Na(+)(in) + urate(in) => 2 Na(+)(out) + urate(out)


name: C3a receptor binds anaphylatoxin C3a (Bos taurus)


name: n H(+)(out) + pyridoxine(out) <=> n H(+)(in) + pyridoxine(in)


name: FADH2 + H2O + NAD(+) + rifamycin SV hemiaminal => FADH2-C4alpha-hydroperoxide + H(+) + NADH + rifamycin SV


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Canis familiaris)


name: (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: L-cysteinyl-[protein] + NAD(+) <=> H(+) + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein]


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Schizosaccharomyces pombe)


name: 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H(+) => 3',3'-c-di-AMP + H2O


name: RHOJ GAPs stimulate RHOJ GTPase activity (Bos taurus)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Expression of IL13-downregulated extracellular proteins (Homo sapiens)


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Gallus gallus)


name: TFAM binds to mitochondrial promoters (Saccharomyces cerevisiae)


name: Inactivation of APC/C via CDC20 sequestration (Xenopus tropicalis)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + soppiline B <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + soppiline C


name: CTP + N-acetyl-D-glucosamine <=> CDP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: beta-D-Gal-(1<->1')-Cer + UDP-alpha-D-galactose <=> alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer + H(+) + UDP


name: [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B + H2O + NADP(+) => [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + H(+) + NADPH + O2


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Dictyostelium discoideum)


name: Release of endostatin-like peptides (Mus musculus)


name: Active ARF recruits coatomer to the Golgi (Plasmodium falciparum)


name: crenolanib-resistant FLT3 mutants don't bind crenolanib (Homo sapiens)


name: MSR1 (SCARA1, SR-A) binds ligands (Homo sapiens)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Xenopus tropicalis)


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Bos taurus)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Sus scrofa)


name: Activation of Rap1 by membrane-associated GEFs (Xenopus tropicalis)


name: AMP + H2O <=> adenine + D-ribose 5-phosphate


name: L-idonate transmembrane transporter activity


name: (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + NAD(+) <=> 2 H(+) + L-pyrrolysine + NADH + NH4(+)


name: WNT5A binds ROR2 and VANGL2 (Homo sapiens)


name: (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) <=> catechol + CO2 + NADH


name: RAC1 binds effectors at the plasma membrane (Bos taurus)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+) => a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Bos taurus)


name: calcitetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (1S)-1,25-dihydroxy-24-oxocalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: Expression of STAT5 upregulated genes (Homo sapiens)


name: a 5,6-dihydrouridine in tRNA + NADP(+) <=> a uridine in tRNA + H(+) + NADPH


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Bos taurus)


name: (S)-usnate + 2 H(+) + NADH => (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+)


name: (4R)-hydroxysphinganine + eicosanoyl-CoA => CoA + H(+) + N-eicosanoyl-(4R)-hydroxysphinganine


name: CAMK4 autophosphorylates (Dictyostelium discoideum)


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Mus musculus)


name: glycyl-L-glutamine(out) + H(+)(out) => glycyl-L-glutamine(in) + H(+)(in)


name: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester => adenosine 3',5'-bisphosphate + H(+) + L-tyrosine methyl ester 4-sulfate


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Homo sapiens)


name: PPO oxidises PPGEN9 to PRIN9 (Dictyostelium discoideum)


name: an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + H2O => 3-methylcytosine + a 2'-deoxyribose 5'-phosphate in double-stranded DNA + H(+)


name: DCC interaction with Ezrin (Canis familiaris)


name: malonate(in) + succinate(out) => malonate(out) + succinate(in)


name: 1-O-alkyl-sn-glycerol + ATP => 1-O-alkyl-sn-glycero-3-phosphate + ADP + H(+)


name: 5-phosphomethyl-dUMP in DNA + ADP + H(+) => 5-hydroxymethyl-dUMP in DNA + ATP


name: an acyl-CoA + tropine = CoA + H(+) + O-acyltropine


name: H(+) + O2 + protoviolaceinate = CO2 + H2O + proviolacein


name: 2-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) => methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + salicylate


name: cytidine(in) + H(+)(in) => cytidine(out) + H(+)(out)


name: chloride(out) + 2 hydrogencarbonate(in) = chloride(in) + 2 hydrogencarbonate(out)


name: p-T774-PKN1 phosphorylates PPP1R14A (Sus scrofa)


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Drosophila melanogaster)


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Gallus gallus)


name: BTRC binds p-S344, 347 NFE2L2 (Bos taurus)


name: beta-D-glucose 1-phosphate + D-glucose => nigerose + phosphate


name: CRHR2-2 binds CRH,UCN,UCN2,UCN3 (Rattus norvegicus)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Rattus norvegicus)


name: H2O + N-eicosanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = (9Z)-octadecenoate + H(+) + N-eicosanoyl-sn-glycero-3-phosphoethanolamine


name: 2,3-epoxyphylloquinone + [protein]-dithiol => [protein]-disulfide + H2O + phylloquinone


name: PGLYRP2 binds bacterial peptidoglycan (Homo sapiens)


name: oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor


name: (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) => 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: (E)-feruloyl-CoA + 2-oxoglutarate + O2 <=> (E)-6-hydroxyferuloyl-CoA + CO2 + succinate


name: (2E,6E)-farnesyl diphosphate => calarene + diphosphate


name: H(+) + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate => L-glutamate + O-phospho-L-serine


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Gallus gallus)


name: 3-oxo-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Bos taurus)


name: DNA endonuclease activity, producing 3'-phosphomonoesters


name: "Endodeoxyribonucleases producing other than 5'-phosphomonoesters"


name: N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(527) in 16S rRNA + S-adenosyl-L-methionine


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Homo sapiens)


name: Formation of the 43S pre-initiation complex (Caenorhabditis elegans)


name: H(+)(out) + L-serine(in) + Na(+)(in) => H(+)(in) + L-serine(out) + Na(+)(out)


name: alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+) => beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose


name: WNT5A:FZD4 is endocytosed (Mus musculus)


name: Activated FGFR1 phosphorylates FRS2 (Homo sapiens)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Dictyostelium discoideum)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Schizosaccharomyces pombe)


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Homo sapiens)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Xenopus tropicalis)


name: (E)-4-hydroxynon-2-en-1-ol + NADP(+) = (E)-4-hydroxynon-2-enal + H(+) + NADPH


name: RPE dimers isomerise RU5P to XY5P (Homo sapiens)


name: 5'-deoxy-5'-fluoroadenosine + L-methionine => fluoride + S-adenosyl-L-methionine


name: ALAD condenses 2 dALAs to form PBG (Danio rerio)


name: 1D-myo-inositol 1,4,5-trisphosphate + H2O => 1D-myo-inositol 1,4-bisphosphate + phosphate


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Rattus norvegicus)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Bos taurus)


name: 2 a 2-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: Tyrosine is hydroxylated to dopa (Dictyostelium discoideum)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Homo sapiens)


name: factor VII -> factor VIIa (Mus musculus)


name: acetyl-CoA + H(+) + 3 malonyl-CoA + S-adenosyl-L-methionine => 3-methylorsellinate + 3 CO2 + 4 CoA + S-adenosyl-L-homocysteine


name: a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(+) + UDP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine


name: IL35 binds IL12RB2:IL12RB2 receptor (Mus musculus)


name: A + dihydrobisanhydrobacterioruberin = AH2 + bisanhydrobacterioruberin


name: ARSB hydrolyses C4S/C6S chains (Homo sapiens)


name: lutein + O2 => (3R)-hydroxy-beta-ionone + (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Homo sapiens)


name: formate + H(+) + menaquinone-8 => CO2 + menaquinol-8


name: a ribonucleoside 5'-triphosphate + H2O => a ribonucleoside 5'-diphosphate + H(+) + phosphate


name: (2E,6E)-farnesyl diphosphate => (+)-beta-selinene + diphosphate


name: ADP(in) + FMN(out) <=> ADP(out) + FMN(in)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Homo sapiens)


name: Cleavage of C3 by fluid-phase C3i:factor B (Gallus gallus)


name: POU5F1 (OCT4), SOX2, NANOG bind the STAT3 promoter (Homo sapiens)


name: (-)-alpha-amorphene + diphosphate => (2E,6E)-farnesyl diphosphate


name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Xenopus tropicalis)


name: dUTP + H2O => dUMP + pyrophosphate (Mus musculus)


name: glyoxylate + L-tryptophan = glycine + indole-3-pyruvate


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 <=> 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate


name: alpha-maltoheptaose + phosphate = alpha-D-glucose 1-phosphate + alpha-maltohexaose


name: H(+) + pyrrole-2-carboxylate <=> 1H-pyrrole + CO2


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 => prostaglandin G2


name: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) <=> 1,2-dihydroxydibenzothiophene + H(+) + NADH


name: Autocatalytic activation of MMP1 (Bos taurus)


name: LC3 de-lipidation by ATG4 (Plasmodium falciparum)


name: HMIT co-transports myo-inositol with a proton (Homo sapiens)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate => ADP + ATP + 2 H(+)


name: Budding of COPII coated vesicle (Rattus norvegicus)


name: Transphosphorylation of pLIMK1 (Homo sapiens)


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Saccharomyces cerevisiae)


name: ATG10 dissociates from ATG12:ATG5 (Sus scrofa)


name: LONP1 degrades mitochondrial matrix proteins (Saccharomyces cerevisiae)


name: deoxylimonoate + H2O => deoxylimononate D-ring-lactone + H(+)


name: SNAI1 binds the OCLN gene (Homo sapiens)


name: D-alanine + L-glutamine <=> gamma-L-glutamyl-D-alanine + NH4(+)


name: 2 Fe(II)-[cytochrome c] + fumarate + 2 H(+) => 2 Fe(III)-[cytochrome c] + succinate


name: Formation of DSIF:NELF:early elongation complex (Sus scrofa)


name: AFG3L2 degrades mitochondrial matrix proteins (Xenopus tropicalis)


name: CBL dissociates from ubiquitinated p-SPRY2 (Homo sapiens)


name: RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Bos taurus)


name: PGH2 is isomerised to PGD2 by PTGDS (Mus musculus)


name: SFN dimer binds CDK1 and CCNB1 (Mus musculus)


name: 4-methylumbelliferyl acetate + H2O <=> 4-methylumbelliferone + acetate + H(+)


name: Activated MDA5 binds IPS-1 (Gallus gallus)


name: sphinganine + tetradecanoyl-CoA <=> CoA + H(+) + N-(tetradecanoyl)-sphinganine


name: 3 menaquinone-8 + protoporphyrinogen IX <=> 3 menaquinol-8 + protoporphyrin IX


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (Sus scrofa)


name: (S)-versiconol + NADP(+) <=> (2S-3S)-versiconal hemiacetal + H(+) + NADPH


name: Phosphorylation of COP1 at Ser-387  by ATM (Homo sapiens)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Caenorhabditis elegans)


name: chrysoeriol + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + velutin


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Bos taurus)


name: Proteasome proteolyzes ub-HIF-alpha (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O


name: Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG (Homo sapiens)


name: 6-diazo-5-oxo-L-norleucine + acetyl-CoA => CoA + H(+) + N(alpha)-acetyl-6-diazo-5-oxo-L-norleucine


name: (3R)-3-isocyanylbutanoyl-[ACP] + AMP + diphosphate => (3R)-3-isocyanylbutanoate + ATP + holo-[ACP]


name: (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + H(+) + O2 <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + CO2 + H2O2


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Homo sapiens)


name: FAAH2 hydrolyses AEA to AA and ETA (Caenorhabditis elegans)


name: NADP(+) + prenol => 3-methyl-2-butenal + H(+) + NADPH


name: (1S)-2-methyl-cyclohexylamine + H2O + NAD(+) => 2-methylcyclohexanone + H(+) + NADH + NH4(+)


name: Cleavage of C3 by C3 convertases (Mus musculus)


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Bos taurus)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Caenorhabditis elegans)


name: (E)-4-coumaroyl alcohol + A <=> (E)-4-coumaraldehyde + AH2


name: 3-oxochol-4-en-22-oyl-CoA + H(+) + NADH + O2 => 9alpha-hydroxy-3-oxochol-4-en-22-oyl-CoA + H2O + NAD(+)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: cycloartenol + S-adenosyl-L-methionine <=> cyclolaudenol + H(+) + S-adenosyl-L-homocysteine


name: FADH2 + trans-2-undecenoyl-CoA => FAD + H(+) + undecanoyl-CoA


name: Ubiquitinated RNF41 binds P-USP8 (Gallus gallus)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Danio rerio)


name: 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA


name: LYPLA2 hydrolyses PALM-C3,4-GAP43 (Bos taurus)


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Rattus norvegicus)


name: AVPR1A,B bind desmopressin (Rattus norvegicus)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Xenopus tropicalis)


name: H2O + kynurenate => 4-(2-aminophenyl)-2,4-dioxobutanoate


name: [thioredoxin]-dithiol + prostaglandin H2 <=> [thioredoxin]-disulfide + prostaglandin F2alpha


name: a nucleoside 2',3'-cyclic phosphate + H2O <=> a nucleoside 3'-phosphate + H(+)


name: factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain (Sus scrofa)


name: OCT3 mediates renal clearance of organic cations (Canis familiaris)


name: 3-(2,4-dioxopentyl)-2,3,6,8,9-pentahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+) => 3-(2,4-dioxopentyl)-3,6,8,9-tetrahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2


name: CMP(out) + CMP-N-acetyl-beta-neuraminate(in) = CMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: 5alpha-cholest-8,14-dien-3beta-ol + H(+) + NADPH => 5alpha-cholest-8-en-3beta-ol + NADP(+)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Homo sapiens)


name: Rheb in the MTORC1 complex hydrolyses GTP (Danio rerio)


name: 7beta-hydroxytaxusin + O2 + reduced [NADPH--hemoprotein reductase] => 2alpha,7beta-dihydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid + 8 oxidized 2[4Fe-4S]-[ferredoxin] <=> a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: alpha,alpha-trehalose(out) + ATP + H2O => ADP + alpha,alpha-trehalose(in) + H(+) + phosphate


name: Cdc6 protein is phosphorylated by CDK (Danio rerio)


name: A + beta-cyclopiazonate = AH2 + alpha-cyclopiazonate


name: oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Schizosaccharomyces pombe)


name: Iodide is taken up by thyroid epithelial cells (Homo sapiens)


name: CoA + propyl butanoate => 1-propanol + butanoyl-CoA


name: Alpha-1-Microglobulin is cleaved (Gallus gallus)


name: ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+)


name: erythromycin D + H(+) + NADPH + O2 <=> erythromycin C + H2O + NADP(+)


name: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4(+)


name: Latent TGF-beta-1 is cleaved by FURIN (Caenorhabditis elegans)


name: TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers and YY1 stimulate ERBB2 gene expression (Homo sapiens)


name: Anti-MET small tyrosine kinase inhibitors bind MET (Gallus gallus)


name: alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP-beta-L-fucose => alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP + H(+)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Caenorhabditis elegans)


name: 2,4,6-trichlorophenol + FADH2 + O2 => 2-chloro-6-hydroxy-1,4-benzoquinone + 2 chloride + FAD + 3 H(+)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + octanoyl-CoA = 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA


name: XPO1 binds p-S69,73 MITF-M (Drosophila melanogaster)


name: E2F6:TFDP1 binds to MGA:MAX (Gallus gallus)


name: TBC1D10A (EPI64) binds ARF6:GTP (Rattus norvegicus)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Bos taurus)


name: H2O + octanoyl-CoA => CoA + H(+) + octanoate


name: glutathione + thiosulfate <=> H(+) + S-sulfanylglutathione + sulfite


name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Homo sapiens)


name: FAD + H(+) + octanoyl-CoA => (2E)-octenoyl-CoA + FADH2


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Mus musculus)


name: H2O + N-(octanoyl)-sphing-4-enine-1-phosphate => N-octanoylsphing-4-enine + phosphate


name: β1-agonists bind ADRB1 (Xenopus tropicalis)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Saccharomyces cerevisiae)


name: Formation of Ragulator complex (Sus scrofa)


name: H(+) + N-acyl-15-methylhexadecasphinganine + NADPH + O2 => H2O + N-acyl-4-hydroxy-15-methylhexadecasphinganine + NADP(+)


name: RPA binds to the Flap on the C-strand (Mus musculus)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + 2 H(+) + phosphate => 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Caenorhabditis elegans)


name: DOLK phosphorylates DCHOL to DOLP (Sus scrofa)


name: 1-carboxybiuret + H2O = NH4(+) + urea-1,3-dicarboxylate


name: Binding of GRB2 to GAB1 (Rattus norvegicus)


name: eNoSC dimethylates histone H3 at lysine-9 (Rattus norvegicus)


name: chloride(in) + hydrogencarbonate(out) => chloride(out) + hydrogencarbonate(in)


name: a globoside IV3GalNAc-Gb4Cer + H2O => a globoside Gb4Cer + N-acetyl-alpha-D-galactosamine


name: ATP + holo-[peptidyl-carrier protein] + L-proline = AMP + diphosphate + L-prolyl-[peptidyl-carrier protein]


name: HCAR2 binds HCAR2 ligands (Homo sapiens)


name: Loading and methylation of Sm proteins onto SMN Complexes (Mus musculus)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Caenorhabditis elegans)


name: hexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] => 26-hydroxyhexacosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SIRT4 cleaves lipoyl from DLAT (Drosophila melanogaster)


name: 2 Na(+)(out) + pyruvate(out) <=> 2 Na(+)(in) + pyruvate(in)


name: all-trans-4-hydroxy-13,14-dihydroretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-13,14-dihydroretinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Activation of proMMP9 by proteases (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate <=> african-3-ene + diphosphate


name: H(+) + 2 H2O2 + hexadecanoate <=> CO2 + 3 H2O + pentadecanal


name: 2-oxo-ATP + H2O = 2-oxo-AMP + diphosphate + H(+)


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Homo sapiens)


name: an aliphatic primary amide => an aliphatic nitrile + H2O


name: 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Xenopus tropicalis)


name: L-glutamate(in) + 2 Na(+)(in) => L-glutamate(out) + 2 Na(+)(out)


name: H2O + L-tyrosine + O2 <=> 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: (15Z)-3-oxotetracosenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(15Z)-tetracosenoyl-CoA + NADP(+)


name: ATP + propanoate <=> ADP + propanoyl phosphate


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Caenorhabditis elegans)


name: acetoacetate(in) + 2 Na(+)(in) => acetoacetate(out) + 2 Na(+)(out)


name: HSPG binds LPL dimer (Xenopus tropicalis)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Canis familiaris)


name: Retrograde COPI vesicles bind kinesin and microtubules (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoate + O2 => (13R)-hydroperoxy-(9Z,11E)-octadecadienoate


name: RNA polymerase II CTD heptapeptide repeat Y1 kinase activity


name: (2R,3S)-3-isopropylmalate + NAD(+) <=> (2S)-2-isopropyl-3-oxosuccinate + H(+) + NADH


name: 20beta-dihydrocorticosterone + NADP(+) => corticosterone + H(+) + NADPH


name: UBQLNs bind UIM-containing adaptor proteins (Drosophila melanogaster)


name: alpha-maltoheptaose + phosphate <=> alpha-D-glucose 1-phosphate + alpha-maltohexaose


name: 3-[[[(2R,3R)-3-carboxyoxiran-2-yl]carbonyl]amino]-L-alanine + ATP + L-valine = ADP + dapdiamide E + H(+) + phosphate


name: 3,4-dinitrotoluene + NADH + O2 = 4-methyl-6-nitrocatechol + NAD(+) + nitrite


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Dimerization of cytosolic FGFR1 fusion proteins (Homo sapiens)


name: C37-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+) => 2 (S)-methylmalonyl-CoA + 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH


name: p-PKR dimer phosphorylates DHX9 (Homo sapiens)


name: PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL4 complex (Canis familiaris)


name: Formation of GINS complex (Homo sapiens)


name: 3-oxoheptanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxyheptanoyl-[ACP] + NADP(+)


name: (3R,4R)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromene-4,7-diol <=> (-)-maackiain + H2O


name: ARMS:Crk complex binds to active TrkA receptor (Homo sapiens)


name: chorismate + inosine + phosphoenolpyruvate <=> futalosine


name: Thrombin binding to GP1b:IX:V (Mus musculus)


name: RUNX3 binds SMAD3 and SMAD4 (Canis familiaris)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Danio rerio)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Sus scrofa)


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Homo sapiens)


name: 6-hydroxyphenazine-1-carboxylate + 2 H(+) + NADH + O2 = 1,6-dihydroxyphenazine + CO2 + H2O + NAD(+)


name: H2O + N-acetyl-D-galactosamine + O2 = H(+) + H2O2 + N-acetyl-D-galactosaminate


name: a 1,2-diacyl-sn-glycerol + a sterol => a 1-acyl-sn-glycerol + a sterol ester


name: alfacalcidol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> calcitriol + H2O + 2 oxidized [adrenodoxin]


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Bos taurus)


name: ACER3 hydrolyzes phytoceramide (Canis familiaris)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Sus scrofa)


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Gallus gallus)


name: p-S295-PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)


name: (R)-phenylacetylcarbinol + NAD(+) => 1-phenyl-1,2-propanedione + H(+) + NADH


name: alpha-D-galactose 1-phosphate + L-rhamnopyranose => beta-D-galactosyl-(1->4)-L-rhamnose + phosphate


name: [alginate](n) + GDP-alpha-D-mannuronate = [alginate](n+1) + GDP + H(+)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Canis familiaris)


name: SDK2 homophillic interaction (Gallus gallus)


name: glyphosate + H2O + O2 => aminomethylphosphonate + glyoxylate + H(+) + H2O2


name: (+)-dehydrodiconiferyl acid + 2 a quinone + H2O => (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: guanosine(10) in tRNA + S-adenosyl-L-methionine <=> H(+) + N(2)-methylguanosine(10) in tRNA + S-adenosyl-L-homocysteine


name: 1-O-hexadecyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH => 1-O-hexadecyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + malonyl-CoA = (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + CO2 + CoA


name: H(+) + prostaglandin E2 + sn-glycerol 3-phosphocholine => 2-(prostaglandin E2)-sn-glycero-3-phosphocholine + H2O


name: Noradrenaline is converted to adrenaline (Rattus norvegicus)


name: a (3E)-enoyl-CoA + H2O => a 4-saturated-(3S)-3-hydroxyacyl-CoA


name: RHOB translocates to the endosome membrane (Rattus norvegicus)


name: H2O + pravastatin lactone = H(+) + pravastatin


name: CDC42 and PIP2 bind WASL, activating it (Caenorhabditis elegans)


name: 3 H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine => N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine


name: Initiation of SAHF formation (Mus musculus)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 1-O-methyl-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Gallus gallus)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Xenopus tropicalis)


name: PGH2 is degraded to 12S-HHT and MDA by TBXAS1 (Rattus norvegicus)


name: ADPRM hydrolyses ADP-ribose to R5P and AMP (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Rattus norvegicus)


name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity


name: DHRS7B reduces GO3P to HXDG3P (Drosophila melanogaster)


name: a ganglioside GA2 (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetyl-beta-D-galactosamine


name: Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Sus scrofa)


name: HIPK2 phosphorylates TP53 (Mus musculus)


name: UBA1 adenylates ubiquitin in the nucleoplasm (Danio rerio)


name: PSIP1 binds MEN1 associated with MLL2 complex (Drosophila melanogaster)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Sus scrofa)


name: D-glucose + stigmasterol => H2O + stigmasteryl 3-beta-D-glucoside


name: Digestion of diacylglycerols by extracellular PTL:colipase (Mus musculus)


name: (4-octa-1-enyl-2,5-dioxo-2,5-dihydro-3-furanyl)acetate + CoA + H2O => (2E)-decenoyl-CoA + H(+) + oxaloacetate


name: K63polyUb-TAK1 autophosphorylates (Sus scrofa)


name: 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(+) + NADPH => 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADP(+)


name: SLC6A18 transports Gly from extracellular region to cytosol (Drosophila melanogaster)


name: cyclobis-(1->3)-alpha-D-isomaltosyl + D-maltotriose => alpha-isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-D-maltotriose


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Bos taurus)


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Canis familiaris)


name: IL17RD binds p-2S MAP2Ks and MAPKs (Sus scrofa)


name: TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene (Homo sapiens)


name: a carboxylate(out) + nicotinate(in) <=> a carboxylate(in) + nicotinate(out)


name: 3'-phosphoadenylyl sulfate + testosterone 17-O-(beta-D-glucuronate) => adenosine 3',5'-bisphosphate + H(+) + testosterone 17-O-(3-sulfo-beta-D-glucuronate)


name: TNF-α is cleaved by ADAM17 (TACE) (Canis familiaris)


name: lithocholate + PAPS => lithocholate sulfate + PAP (Rattus norvegicus)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: Phosphorylation of PLC-gamma (Homo sapiens)


name: NAD(+) + 2 NADPH + 2 oxidized [2Fe-2S]-[ferredoxin] => H(+) + NADH + 2 NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Activated FGFR1 phosphorylates PLCG1 (Homo sapiens)


name: EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene (Homo sapiens)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Canis familiaris)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Drosophila melanogaster)


name: AMP + diphosphate + oxalyl-CoA => ATP + CoA + oxalate


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Bos taurus)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Homo sapiens)


name: MSH2:MSH3 exchanges ADP for ATP (Homo sapiens)


name: GABAB heterodimeric receptor binds GABA (Sus scrofa)


name: p-T774-PKN1 phosphorylates PPP1R14A (Danio rerio)


name: (S)-8-oxocitronellyl enol + NADP(+) <=> (6E)-8-oxogeranial + H(+) + NADPH


name: (S)-methioninol + H2O + NAD(+) = 1-hydroxy-4-(methythio)butan-2-one + H(+) + NADH + NH4(+)


name: CCND1 recruits HDAC4 to RUNX3 (Rattus norvegicus)


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Saccharomyces cerevisiae)


name: CYP3A4, CYP2B6 bind ritonavir (Rattus norvegicus)


name: a carboxylate + choline + H(+) => an acylcholine + H2O


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Rattus norvegicus)


name: hypoxanthine + NH4(+) => adenine + H(+) + H2O


name: Dephosphorylation of CK2-modified condensin I (Mus musculus)


name: (11S)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => diphosphate + variecoladiene


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Danio rerio)


name: Delta(2)-thiazoline-2-carboxylate + 2 H(+) + NADPH = L-thiazolidine-2-carboxylate + NADP(+)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Schizosaccharomyces pombe)


name: CTLH E3 ligase ubiquitinates LDHA (Canis familiaris)


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Bos taurus)


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Rattus norvegicus)


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Canis familiaris)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate => 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O


name: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O => (2S)-2-isopropylmalate + CoA + H(+)


name: CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 (Homo sapiens)


name: a 2-amino-4-hydroxypteridine + H(+) + H2O = a 2,4-dihydroxypteridine + NH4(+)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 <=> 2-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-glycerol


name: SIRT1,SIRT3 deacetylate FOXO3 (Caenorhabditis elegans)


name: MAPK1-dependent phosphorylation of MITF-M (Mus musculus)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 = 15-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate


name: (2Z,6E)-farnesyl diphosphate => (-)-beta-curcumene + diphosphate


name: Transport of MHC heterotrimer to ER exit site (Canis familiaris)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Xenopus tropicalis)


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Mus musculus)


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Homo sapiens)


name: indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose <=> (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP


name: (E)-(indol-3-yl)acetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] => 1-aci-nitro-2-(1H-indol-3-yl)ethane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + H2O + L-methionine(out) <=> ADP + H(+) + L-methionine(in) + phosphate


name: a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate


name: Formation of the Spliceosomal Pre-B complex (Homo sapiens)


name: SERPING1 is secreted (Drosophila melanogaster)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Rattus norvegicus)


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Gallus gallus)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Bos taurus)


name: 2,5-dioxopentanoate + H2O + NAD(+) => 2-oxoglutarate + 2 H(+) + NADH


name: calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Canis familiaris)


name: 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine <=> 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: H2O + IMP <=> 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide


name: (S)-lactate(in) + H(+)(in) <=> (S)-lactate(out) + H(+)(out)


name: MAP2K6 phosphorylates PIP4K2B (Caenorhabditis elegans)


name: all-trans-13,14-dihydroretinol + NAD(+) <=> all-trans-13,14-dihydroretinal + H(+) + NADH


name: Moderate kinase activity BRAF mutants bind RAS:GTP (Homo sapiens)


name: ISGylation of DDX58 (Dictyostelium discoideum)


name: adenine(out) + H(+)(out) => adenine(in) + H(+)(in)


name: 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 => H2O + NADP(+) + neopentalenolactone D


name: GSTs transfer GSH to NAPQI to form APAP-SG (Bos taurus)


name: 8-hydroxycopalyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(in) + ATP + H2O <=> (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(out) + ADP + H(+) + phosphate


name: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + phosphate


name: 2-oxoglutarate + 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + O2 => 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + CO2 + succinate


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Caenorhabditis elegans)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Mus musculus)


name: ACP phosphopantetheine attachment site binding


name: D-glutamate + H2O + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+)


name: 11-cis-retinol + hexadecanoyl-CoA => 11-cis-retinyl hexadecanoate + CoA


name: 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + O2 <=> a 2'-deoxycytidine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: beta-alanyl-dopamine + H2O <=> beta-alanine + dopamine


name: p-5Y-RET complexes bind GRB2 (Sus scrofa)


name: XIAP monoubiquinates TLE (Rattus norvegicus)


name: MMACHC decyanates CNCbl (Xenopus tropicalis)


name: Movement of clathrin coated vesicles into early endosome (Gallus gallus)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Drosophila melanogaster)


name: acetyl-CoA + N-terminal L-methionyl-L-valyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-valyl-[protein]


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O => 1D-myo-inositol 1,4,5,6-tetrakisphosphate + phosphate


name: RAP1A exchanges GDP for GTP (Dictyostelium discoideum)


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Sus scrofa)


name: a 3-oxosteroid + CO2 + NADPH => a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+)


name: 3-deoxyfructose + NADP(+) = 3-deoxyglucosone + H(+) + NADPH


name: CPN, CPB2 cleave C3a, C5a (Rattus norvegicus)


name: LGI1 binds ADAM22 and ADAM23 (Bos taurus)


name: Bacterial Flagellin binds TLR5 homodimer (Gallus gallus)


name: SIRT4 cleaves lipoyl from DLAT (Danio rerio)


name: H2O + streptomycin 6-phosphate => phosphate + streptomycin


name: Nascent N is phosphorylated (Homo sapiens)


name: UROD decarboxylates URO3 to COPRO3 (Drosophila melanogaster)


name: H2O + S-[(2E,6E,10E)-geranylgeranyl]-L-glutathione <=> L-glutamate + S-[(2E,6E,10E)-geranylgeranyl]-L-cysteinylglycine


name: 5 AH2 + all-trans-3,4-didehydrolycopene => 15-cis-phytoene + 5 A


name: a long-chain (2E)-enoyl-CoA + H2O2 => a long-chain 2,3-saturated fatty acyl-CoA + O2


name: 1D-myo-inositol 3-phosphate + CDP-2,3-bis-O-(phytanyl)-sn-glycerol = CMP + H(+) + saturated 1-archaetidyl-1D-myo-inositol 3-phosphate


name: H(+) + H2O2 + harderoheme III => CO2 + 2 H2O + heme b


name: H(+)(in) + methotrexate(in) = H(+)(out) + methotrexate(out)


name: WDR5 binds Me2sR3-replicative histone H3 (Saccharomyces cerevisiae)


name: 3''-dehydroisoorientin <=> 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)


name: L-alanine + vanillin => pyruvate + vanillylamine


name: SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Danio rerio)


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Mus musculus)


name: (E)-sinapoyltartronate + CoA => (E)-sinapoyl-CoA + hydroxymalonate


name: beta-muricholate + deoxycholoyl-CoA = beta-muricholoyl-CoA + deoxycholate


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Rattus norvegicus)


name: GCHFR binds to GCH1 and negatively regulates its activity (Mus musculus)


name: NOX2 generates superoxide from oxygen (Gallus gallus)


name: ATM recognizes H2AFX-Nucleosomes (Saccharomyces cerevisiae)


name: 3,4-dihydroxybenzoate + NAD(+) + sulfite => 4-sulfobenzoate + NADH + O2


name: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Mus musculus)


name: [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity


name: SRD5A3 reduces pPNOL to DCHOL (Schizosaccharomyces pombe)


name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1,2-dihexanoyl-sn-glycerol <=> 1,2-dihexanoyl-3-(9Z-octadecenoyl)-sn-glycerol + CoA


name: 15-oxoprostaglandin F1alpha + H(+) + NADPH => 13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+)


name: GST trimers transfer GS from GSH to luminal substrates (Homo sapiens)


name: CPO transforms COPRO3 to PPGEN9 (Dictyostelium discoideum)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Caenorhabditis elegans)


name: A + dihydrobisanhydrobacterioruberin => AH2 + bisanhydrobacterioruberin


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Saccharomyces cerevisiae)


name: Interaction of Tie2 with Ang1 (Canis familiaris)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Schizosaccharomyces pombe)


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Gallus gallus)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Schizosaccharomyces pombe)


name: TFAM translocates from the cytosol to the mitochondrial matrix (Homo sapiens)


name: STAT1 associates with IL6ST:IL6ST (Mus musculus)


name: (9Z)-octadecenoate + H(+) + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => H2O + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Canis familiaris)


name: PVR:PVRL3 trans heterodimer interaction (Mus musculus)


name: dihydroorotate dehydrogenase (fumarate) activity


name: Squalene is oxidized to its epoxide (Schizosaccharomyces pombe)


name: Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Bos taurus)


name: ACSF2 ligates CoA-SH to MCFA (Caenorhabditis elegans)


name: OCT2 mediates tubular secretion of organic cations in the kidney (Mus musculus)


name: Keratin type I binds keratin type II (Homo sapiens)


name: MDM2 translocates to the nucleus (Rattus norvegicus)


name: HMGCR dimer reduces bHMG-CoA to MVA (Mus musculus)


name: Polyubiquitination of substrate (Dictyostelium discoideum)


name: ADP-Ribosylation of HNP-1 (Mus musculus)


name: G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) (Drosophila melanogaster)


name: Iodide is taken up by thyroid epithelial cells (Caenorhabditis elegans)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) (Rattus norvegicus)


name: Defective CP does not oxidise Fe2+ to Fe3+ (Homo sapiens)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)


name: 24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: 5-deoxy-alpha-D-ribose 1-phosphate = 5-deoxy-D-ribulose 1-phosphate


name: 3,3',5'-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) => 3,3',5'-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: 5-formimidoyltetrahydrofolate + glycine <=> (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine


name: Association of Cx43 with TJP1 (Homo sapiens)


name: IKBA is phosphorylated by Phospho IKKB kinase (Mus musculus)


name: ASAP1 stimulates GTPase activity of ARF4 (Danio rerio)


name: Fusion of COPII vesicle with Golgi complex (Homo sapiens)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Caenorhabditis elegans)


name: RAC2 translocates to the phagocytic vesicle membrane (Mus musculus)


name: PHF8 demethylates MeK21-histone H4 (Schizosaccharomyces pombe)


name: 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+) => 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose


name: TULP3 is required for GPR161 localization in the cilium (Canis familiaris)


name: 2 H(+)(out) + L-alanyl-L-alanine(out) <=> 2 H(+)(in) + L-alanyl-L-alanine(in)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Gallus gallus)


name: MITF-M-dependent PLK1 expression (Homo sapiens)


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Rattus norvegicus)


name: NOTCH3 coactivator complex binds the PTCRA gene promoter (Homo sapiens)


name: PYGB dimer, b form + 2 AMP <=> PYGB b dimer:AMP complex (Homo sapiens)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: benzylamine + pyruvate => benzaldehyde + L-alanine


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Schizosaccharomyces pombe)


name: D-glyceraldehyde 3-phosphate + H2O + NADP(+) = (2R)-3-phosphoglycerate + 2 H(+) + NADPH


name: beta-nicotinamide D-riboside + H2O = D-ribose + H(+) + nicotinamide


name: Ubiquitinated Cdc6 is degraded by the proteasome (Rattus norvegicus)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Mus musculus)


name: Phosphorylated Cdc6 is exported from the nucleus (Plasmodium falciparum)


name: 2',3'-cyclophospho-GMP + H2O => guanosine 2'-phosphate + H(+)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2 (Homo sapiens)


name: NEK9 phosphorylates NEK6/NEK7 (Bos taurus)


name: ADK phosphorylates RBV (Dictyostelium discoideum)


name: (2E,6E,10E)-geranylgeranyl diphosphate + 5 isopentenyl diphosphate => all-trans-nonaprenyl diphosphate + 5 diphosphate


name: H(+) + N-acetyl-alpha-D-muramate 1-phosphate + UDP = phosphate + UDP-N-acetyl-alpha-D-muramate


name: LIG1 binds APEX1 and PCNA at SSB (Plasmodium falciparum)


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Canis familiaris)


name: a ganglioside GT1a + CMP-N-acetyl-beta-neuraminate => a ganglioside GQ1b + CMP + H(+)


name: D-cycloserine(in) + H(+)(in) => D-cycloserine(out) + H(+)(out)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Mus musculus)


name: Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Bos taurus)


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate <=> 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: SUMOylation of TDG with SUMO2,3 (Homo sapiens)


name: BMP2 binds to the receptor complex (Caenorhabditis elegans)


name: Autoproteolytic cleavage of Hh precursors (Canis familiaris)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Drosophila melanogaster)


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Gallus gallus)


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Homo sapiens)


name: Bile salts dissociate from FABP6 (Caenorhabditis elegans)


name: AKT phosphorylates PHF20 (Drosophila melanogaster)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + tetradecanoyl-CoA => (9Z)-tetradecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Bos taurus)


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Sus scrofa)


name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Dictyostelium discoideum)


name: a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+) => an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose


name: alpha,alpha-trehalose 6-phosphate + phosphate => beta-D-glucose 1-phosphate + D-glucose 6-phosphate


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Sus scrofa)


name: an aldehyde + 2 Fe(III)-[cytochrome c] + H2O = a carboxylate + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: (2R,3S)-2,3-dimethylmalate <=> dimethylmaleate + H2O


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Homo sapiens)


name: (4R)-hydroxysphing-(8E)-enine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphing-(8E)-enine


name: L-tryptophan + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-tryptophan + oxidized [NADPH--hemoprotein reductase]


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Homo sapiens)


name: SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane (Canis familiaris)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Caenorhabditis elegans)


name: (N(7)-methyl 5'-triphospho-guanosine)-adenosine + a 5'-end phospho-ribonucleoside in mRNA + H(+) => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine-phospho-ribonucleoside in mRNA + H2O


name: "glyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (phosphorylating)"


name: Dopa is decarboxylated to dopamine (Danio rerio)


name: CoA + octyl acetate => acetyl-CoA + octan-1-ol


name: 2,3-dihydroxydodecanoate + H2O => 2-hydroxydodecanoate + H2O2


name: USP9X (FAM) deubiquitinates SMAD4 (Bos taurus)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Mus musculus)


name: 2-oxoglutarate + 4-aminobutanoate <=> L-glutamate + succinate semialdehyde


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + dodecanoyl-CoA => 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + CoA


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Sus scrofa)


name: 1-acyl LPG is acylated to PG by LPGAT (Danio rerio)


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Drosophila melanogaster)


name: L-phenylalanine(out) + L-tryptophan(in) = L-phenylalanine(in) + L-tryptophan(out)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NAD(+) + propanoate => acrylate + H(+) + NADH


name: 2-AG hydrolysis to arachidonate by MAGL (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-O-hexadecyl-2-acetyl-sn-glycerol = 1-O-hexadecyl-2-acetyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Dictyostelium discoideum)


name: 3 H(+) + nicotianamine + 3 S-methyl-5'-thioadenosine => 3 S-adenosyl-L-methionine


name: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Caenorhabditis elegans)


name: D-maltopentaose + O2 <=> D-maltopentaono-1,5-lactone + H2O2


name: Arachidonic acid is oxidised to 5S-HpETE by ALOX5 (Dictyostelium discoideum)


name: Interaction of NUMB with L1 (Xenopus tropicalis)


name: L-threonyl-[protein] + UTP = diphosphate + uridylyl-L-threonyl-[protein]


name: a menaquinol + 2 nitric oxide => a menaquinone + H2O + nitrous oxide


name: H(+) + NADH + O2 + quinolin-4-ol <=> H2O + NAD(+) + quinoline-3,4-diol


name: 3,3',5-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) <=> 3,3',5-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: H2 + n sulfur => H(+) + hydrogen sulfide + (n-1) sulfur


name: an alpha-Kdo-(2->6)-lipid IVA + ATP => a 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA + ADP + H(+)


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + succinate


name: aurachin B + H(+) + H2O <=> 3,4-dihydroxy-2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O <=> 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + octadecanoate


name: diphosphate + neoverrucosan-5beta-ol => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: STAT5 association with GHR (Homo sapiens)


name: WWTR1:SMAD translocates to the nucleus (Drosophila melanogaster)


name: ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA (Rattus norvegicus)


name: "[heparan sulfate]-glucosamine 3-sulfotransferase 1"


name: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Bos taurus)


name: sorbitol transmembrane transporter activity


name: [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + CO2 + succinate => 2-oxoglutarate + [2-(trimethylamino)ethyl]phosphonate + O2


name: glycyrrhetaldehyde + O2 + reduced [NADPH--hemoprotein reductase] = glycyrrhetinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GSTO dimers reduce DeHA to AscH- (Caenorhabditis elegans)


name: 2 H(+) + H2O + thiocyanate => carbonyl sulfide + NH4(+)


name: 2 Fe(II)-[cytochrome c] + 2 H(+) + H2O2 = 2 Fe(III)-[cytochrome c] + 2 H2O


name: DNMT3A binds Me2sR4-HIST1H4 (Homo sapiens)


name: (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + O2 <=> (S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-1,3-oxazole-[protein] + H2O2


name: (25R)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (25R)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: D-serine(in) + L-alanine(out) => D-serine(out) + L-alanine(in)


name: a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein] => a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Bos taurus)


name: RCE1 cleaves S-Farn proRAS proteins (Mus musculus)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Drosophila melanogaster)


name: SDK1 homophillic interaction (Gallus gallus)


name: ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE (Bos taurus)


name: HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 (Homo sapiens)


name: CDSN binds the cornified envelope (Mus musculus)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Danio rerio)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Mus musculus)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Saccharomyces cerevisiae)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Rattus norvegicus)


name: (S)-malate + NADP(+) <=> CO2 + NADPH + pyruvate


name: 4-hydoxytryptamine 4-phosphate + ADP + H(+) => 4-hydroxytryptamine + ATP


name: EXA4 is converted to EXC4 by LTC4S (Bos taurus)


name: 4-(hydroxyamino)quinoline N-oxide + H2O + 2 NADP(+) <=> 4-nitroquinoline N-oxide + 2 H(+) + 2 NADPH


name: RSF complex binds the centromere (Sus scrofa)


name: ethanol + 2 Fe(III)-[cytochrome c] => acetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: RBFOX1 gene expression is inhibited by MECP2 (Homo sapiens)


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate => [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)


name: 3-bromo-4-hydroxybenzoate + bromide + 3 H(+) + NADPH + O2 = 2,4-dibromophenol + CO2 + 2 H2O + NADP(+)


name: a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycerol


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Rattus norvegicus)


name: B-RAF dissociates from S111/S120 p-SPRY2 (Canis familiaris)


name: p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene (Homo sapiens)


name: Parenchymal atROL translocates to HSCs (Canis familiaris)


name: ethyl (9Z)-hexadecenoate + H2O <=> (9Z)-hexadecenoate + ethanol + H(+)


name: H2O + O2 + thermospermine <=> 3-aminopropanal + H2O2 + spermidine


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Saccharomyces cerevisiae)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine


name: DCXR tetramer reduces L-xylulose to xylitol (Sus scrofa)


name: (-)-4'-methoxycyclopeptine + 2-oxoglutarate + O2 = (Z)-4'-methoxydehydrocyclopeptine + CO2 + H2O + succinate


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O => a 2-acyl-sn-glycerol 3-phosphate + a fatty acid + H(+)


name: 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: 3-(indol-3-yl)lactate + NAD(+) <=> H(+) + indole-3-pyruvate + NADH


name: ERBB3 binds neuregulins (Canis familiaris)


name: ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Homo sapiens)


name: (3S)-hydroxyhexadecanoyl-CoA <=> (2E)-hexadecenoyl-CoA + H2O


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Bos taurus)


name: 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol <=> 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: (2S)-3-sulfolactate + 2 H(+) + NADH => (2S)-3-sulfolactaldehyde + H2O + NAD(+)


name: GPCR neuropeptide receptor binds neuropeptides B and W (Gallus gallus)


name: beta-muricholoyl-CoA + deoxycholate => beta-muricholate + deoxycholoyl-CoA


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) = (6S)-5-formyl-5,6,7,8-tetrahydrofolate(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADH => all-trans-lycopaoctaene + 2 diphosphate + NAD(+)


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Homo sapiens)


name: RHOC activates endoplasmic reticulum effectors (Bos taurus)


name: Phosphorylation of CTLA-4 (Mus musculus)


name: imaginal disc growth factor receptor binding


name: ATP + H2O + Mn(2+)(in) <=> ADP + H(+) + Mn(2+)(out) + phosphate


name: 3beta-hydroxy-5alpha-androstan-17-one + H(+) + NADPH => 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: 1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate <=> CO2 + demethylphylloquinone + diphosphate


name: 2 mycothiol + NADP(+) => H(+) + mycothione + NADPH


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Gallus gallus)


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Xenopus tropicalis)


name: RNF41 ubiquitinates activated ERBB3 (Drosophila melanogaster)


name: (9R,10S)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-(9R,10S)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of hydroxylysyl-pyridinoline cross-links (Canis familiaris)


name: 6-decylubiquinone + 2 thiosulfate <=> 6-decylubiquinol + tetrathionate


name: Formation of classic pathway C5 convertase (Xenopus tropicalis)


name: H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate => AMP + ATP + 2 H(+)


name: L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-methionine = 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-homocysteine


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Plasmodium falciparum)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] => 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RASA1 stimulates RAS GTPase activity (Gallus gallus)


name: 5-dehydro-4-deoxy-D-glucarate + H2O => galactarate


name: H(+) + kanamycin X + UDP => 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine


name: (2Z,6Z)-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphate


name: D-xylulose 5-phosphate + phosphate <=> acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O


name: Release of platelet cytosolic components (Xenopus tropicalis)


name: 3-ethylmalate + CoA + H(+) => butanoyl-CoA + glyoxylate + H2O


name: NADP(+) + reduced coenzyme F420-(gamma-L-Glu)(n) = 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: a polyvinyl alcohol + n O2 <=> an oxidized polyvinyl alcohol + n H2O2


name: 7,8-dihydrofolate + NADP(+) <=> folate + H(+) + NADPH


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Drosophila melanogaster)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Sus scrofa)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Rattus norvegicus)


name: hexan-1-ol + NAD(+) => H(+) + hexanal + NADH


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-Glc + GDP + H(+) => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose


name: Tropoelastin forms aggregate globules (Bos taurus)


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Danio rerio)


name: RIP2 is K63 polyubiquitinated (Bos taurus)


name: Cleavage of thymine by TDG glycosylase (Mus musculus)


name: AMP(out) + UMP(in) => AMP(in) + UMP(out)


name: 17-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose = (9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + H(+) + UDP


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Canis familiaris)


name: GAP binds to PDGF-beta receptors only (Xenopus tropicalis)


name: 4-O-deacetyl-16-O-demethylvindoline + CO2 + succinate => (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + 2-oxoglutarate + O2


name: undecaprenyl-phosphate galactose phosphotransferase activity


name: soyasapogenol B + UDP-alpha-D-glucuronate <=> H(+) + soyasapogenol B 3-O-beta-D-glucuronate + UDP


name: (E)-2-benzylidenesuccinyl-CoA + reduced [electron-transfer flavoprotein] => (R)-2-benzylsuccinyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: a quinone + 5 H(+)(in) + NADH <=> a quinol + 4 H(+)(out) + NAD(+)


name: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O <=> 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Bos taurus)


name: (12R,13S)-epoxy-(9Z)-octadecenoate + O2 = (12R,13S)-epoxy-(10R)-hydroperoxy-(8E)-octadecenoate


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Mus musculus)


name: (E)-4-coumaroyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] => CoA + H(+) + myricetin 3-O-[(6-O-(E)-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: Formation of the CTF18 complex (Homo sapiens)


name: chloride(out) + D-serine(out) + 2 Na(+)(out) = chloride(in) + D-serine(in) + 2 Na(+)(in)


name: ACLY tetramer transforms CIT to Ac-CoA (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base <=> a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Homo sapiens)


name: USP7 deubiquitinates monoubiquitinated PTEN (Drosophila melanogaster)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Drosophila melanogaster)


name: histone H4K20 methyltransferase activity


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2 = 2-dehydro-D-glucose + an aliphatic amine + H2O2


name: "fructosyl amine oxidase (glucosone-forming)"


name: 7-oxoglycolithocholate + H(+) + NADPH => glycoursodeoxycholate + NADP(+)


name: (2S,3R,11R)-aszonalenin + diphosphate => (R)-benzodiazepinedione + dimethylallyl diphosphate


name: KCNH2:KCNE transport K+ from cytosol to extracellular region (Sus scrofa)


name: 5-dehydroepisterol + H(+) + NADPH + O2 => ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2 H2O + NADP(+)


name: (R)-vicianin + H2O <=> mandelonitrile + vicianose


name: MBTPS2 (S2P) cleaves CREB3L3 (Sus scrofa)


name: Recruitment of IKK complex (Gallus gallus)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP


name: DLST transfers succinyl to CoA (Xenopus tropicalis)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Dictyostelium discoideum)


name: tomatidine + UDP-alpha-D-glucose = H(+) + tomatidine 3-O-beta-D-glucopyranoside + UDP


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Homo sapiens)


name: GSDMD (1-275) binds cardiolipin (Gallus gallus)


name: a globoside NORint + UDP-alpha-D-galactose = a globoside NOR2 + H(+) + UDP


name: (S)-isodihydrodehydrodiconiferyl alcohol + NADP(+) => (-)-dehydrodiconiferyl alcohol + H(+) + NADPH


name: (-)-menthol + UDP-alpha-D-glucose <=> (-)-menthyl beta-D-glucoside + H(+) + UDP


name: DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates


name: DNMT1 methylates cytosine in hemimethylated DNA (Homo sapiens)


name: NMRK1 phosphorylates NR to yield NMN (Rattus norvegicus)


name: CRY proteins stabilize unphosphorylated BMAL1:CLOCK,NPAS2 (Homo sapiens)


name: STAT1 associates with IL6ST:IL6ST (Rattus norvegicus)


name: Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Rattus norvegicus)


name: 3a translocates to the ERGIC (Homo sapiens)


name: 5-nitroanthranilate + H(+) + H2O => 5-nitrosalicylate + NH4(+)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)


name: SULT1A3,4 dimers sulfate DA to DAOS (Danio rerio)


name: Phosphorylation of SMO by PKA-C1 (Drosophila melanogaster)


name: SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Homo sapiens)


name: 2 L-homocysteine => H(+) + hydrogen sulfide + L-homolanthionine


name: TRPs transport extracellular Ca2+ to cytosol (Drosophila melanogaster)


name: (+)-premalbrancheamide + 2 chloride + 2 FAD + 4 H(+) <=> (+)-malbrancheamide + 2 FADH2


name: trans-Golgi Network Coat Assembly (Bos taurus)


name: Activation of Potassium transport channels (Gallus gallus)


name: XDH dehydrogenates xanthine to form urate (Rattus norvegicus)


name: Potassium voltage-gated channels close in reponse to PKA (Xenopus tropicalis)


name: Cargo-carrying vesicles bud from the TGN (Sus scrofa)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Xenopus tropicalis)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)


name: 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + archaeosine(15) in tRNA + 2 H(+) + L-1-piperideine-6-carboxylate + L-methionine


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Homo sapiens)


name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A <=> 4-amino-4-deoxy-beta-L-arabinopyranosyl-lipid A + di-trans,octa-cis-undecaprenyl phosphate


name: Initial activation of proMMP2 by MMP1, 7 (Gallus gallus)


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Dictyostelium discoideum)


name: ATP + H2O + taurine(out) = ADP + H(+) + phosphate + taurine(in)


name: 2 2-oxoglutarate + 2 O2 + preaustinoid A => berkeleytrione + 2 CO2 + H2O + 2 succinate


name: KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Rattus norvegicus)


name: adenosine 3',5'-bisphosphate + H(+) + quercetin 3,4'-bissulfate => 3'-phosphoadenylyl sulfate + quercetin 3-sulfate


name: a dicarboxylate(in) + dehydroepiandrosterone 3-sulfate(out) => a dicarboxylate(out) + dehydroepiandrosterone 3-sulfate(in)


name: 15alpha-stemmadenine + NADP(+) <=> 17-dehydrostemmadenine + 2 H(+) + NADPH


name: SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 (Sus scrofa)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a (Homo sapiens)


name: solute:monoatomic cation symporter activity


name: 4-nitroquinoline N-oxide + 2 H(+) + 2 NADH => 4-(hydroxyamino)quinoline N-oxide + H2O + 2 NAD(+)


name: [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate + H(+) => bornane-2,6-dione + H2O


name: GTP + L-tyrosyl-[protein] = diphosphate + O-(5'-guanylyl)-L-tyrosyl-[protein]


name: Dimerization of LIMK1 by Hsp90 (Canis familiaris)


name: BAR domain proteins recruit dynamin (Caenorhabditis elegans)


name: H2O + N-(9Z-octadecenoyl)-L-leucine <=> (9Z)-octadecenoate + L-leucine


name: ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 (Homo sapiens)


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Xenopus tropicalis)


name: (E)-4-coumaroyl-AMP + diphosphate => (E)-4-coumarate + ATP + H(+)


name: NADP(+) + sphinganine => 3-oxosphinganine + H(+) + NADPH


name: formaldehyde + H2O + NAD(+) + theobromine => caffeine + H(+) + NADH + O2


name: Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)


name: ERBB3 binds RNF41 ubiquitin ligase (Mus musculus)


name: Phosphorylation of nephrin by FYN (Drosophila melanogaster)


name: WLS is endocytosed to the early endosome (Bos taurus)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Mus musculus)


name: (1R,3R)-chrysanthemate + 2 H(+) + NADPH => (1R,3R)-chrysanthemal + H2O + NADP(+)


name: Somatostatin receptors bind somatostatin and cortistatin (Rattus norvegicus)


name: (2E)-geranyl diphosphate => (1S,5S)-sabinene + diphosphate


name: 3-hydroxybenzyl alcohol + acetyl-CoA <=> 3-hydroxy-benzyl acetate + CoA


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 19-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-methionine => 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: ABCB1 transports PREDN,PREDL out of kidney cells (Homo sapiens)


name: CTP(out) + dGTP(in) = CTP(in) + dGTP(out)


name: IL10 negatively regulates extracellular inflammatory mediators (Homo sapiens)


name: (S)-phenylacetylcarbinol + NAD(+) = 1-phenyl-1,2-propanedione + H(+) + NADH


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Sus scrofa)


name: 2-(9Z-octadecenoyl)-glycerol + ATP = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: TPCN1/2 transport lysosomal Ca2+ to cytosol  (Xenopus tropicalis)


name: DKK promotes clathrin-dependent internalization of LRP6 (Homo sapiens)


name: GRK2 sequesters activated Gq (Canis familiaris)


name: VAV1 is a GEF for Rho/Rac family GTPases (Xenopus tropicalis)


name: 4-hydroxy-L-threonine = glycine + glycolaldehyde


name: SLC16A10-mediated uptake of aromatic amino acids (Homo sapiens)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+)


name: 3'-phosphoadenylyl sulfate + firefly L-luciferin = adenosine 3',5'-bisphosphate + firefly L-sulfoluciferin + H(+)


name: O2 + 2 reduced coenzyme F420-(gamma-L-Glu)(n) = 2 H(+) + 2 H2O + 2 oxidized coenzyme F420-(gamma-L-Glu)(n)


name: cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine => H(+) + N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Gallus gallus)


name: ATP + pseudouridine = ADP + H(+) + psi-UMP


name: PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Mus musculus)


name: Expression of Interleukin-10 (Homo sapiens)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Mus musculus)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Homo sapiens)


name: (S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Schizosaccharomyces pombe)


name: Association of Emi1 with Cdh1 (Drosophila melanogaster)


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Sus scrofa)


name: UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in) => UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out)


name: DIMBOA + UDP-alpha-D-glucose <=> DIMBOA beta-D-glucoside + H(+) + UDP


name: 5beta-pregnan-3,20-dione + H(+) + NADPH => 3alpha-hydroxy-5beta-pregnan-20-one + NADP(+)


name: 1,6-dihydroxyphenazine N(5),N(10)-dioxide + H2O + NADP(+) => 1,6-dihydroxyphenazine N(5)-oxide + NADPH + O2


name: H2O + neocasomorphin => L-isoleucine + neocasomorphin-(1-5)


name: Activated FGFR2 phosphorylates PLCG1 (Rattus norvegicus)


name: p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus (Sus scrofa)


name: CoA + glycochenodeoxycholate + H(+) => chenodeoxycholoyl-CoA + glycine


name: STAB2:ligand is endocytosed (Canis familiaris)


name: Translocation of DFF to the nucleus (Drosophila melanogaster)


name: 2-oxoglutarate + L-enduracididine + O2 => (3S)-3-hydroxy-L-enduracididine + CO2 + succinate


name: a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Fe-coproporphyrin III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + heme b + 2 L-methionine


name: CYSLTR1 binds CYSLTR1 antagonists (Mus musculus)


name: Translocation of Vav1 to CD28 (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV (Danio rerio)


name: (2E)-octenedioyl-CoA + H2O => (3S)-hydroxyoctanedioyl-CoA


name: STUB1 polyubiquitinates RUNX2 (Gallus gallus)


name: an acetyl ester + H2O <=> acetate + an aliphatic alcohol + H(+)


name: RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Caenorhabditis elegans)


name: Multiubiquitination of Nek2A (Xenopus tropicalis)


name: 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA


name: (3R)-hydroxyoctadecanoyl-CoA <=> (2E)-octadecenoyl-CoA + H2O


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Homo sapiens)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Bos taurus)


name: Association of Cdh1 with the APC/C (Mus musculus)


name: Abortive Initiation After Second Transition (Sus scrofa)


name: a long-chain fatty acyl-AMP + holo-[mycocerosate synthase] => AMP + H(+) + long-chain fatty acyl-[mycocerosate synthase]


name: DCN (decorin) degradation by MMP14 (Homo sapiens)


name: a uridine in RNA + S-adenosyl-L-methionine = a 5-methyluridine in RNA + H(+) + S-adenosyl-L-homocysteine


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Gallus gallus)


name: Autocatalytic activation of proMMP2 (Rattus norvegicus)


name: furfural + H2O + NAD(+) <=> 2-furoate + 2 H(+) + NADH


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Canis familiaris)


name: Small molecule inhibitor binds RIPK1, RIPK3 (Canis familiaris)


name: 4alpha-carboxyzymosterol + NAD(+) <=> CO2 + NADH + zymosterone


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Bos taurus)


name: KIT binds type II TKIs (Canis familiaris)


name: NADP(+) + tauroursodeoxycholate <=> 7-oxotaurolithocholate + H(+) + NADPH


name: voltage-gated sodium channel activity involved in bundle of His cell action potential


name: D-arabinose + NAD(+) = D-arabinono-1,4-lactone + H(+) + NADH


name: SYK is a substrate for JAK1 (Rattus norvegicus)


name: TLR1:TLR2 is recruited to ligand:CD14 (Homo sapiens)


name: Loading of antigenic peptides (Mus musculus)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Rattus norvegicus)


name: A + a 3-oxo-5beta-steroid => a 3-oxo-Delta(4)-steroid + AH2


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Rattus norvegicus)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Sus scrofa)


name: Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Homo sapiens)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Plasmodium falciparum)


name: Monoiodinated tyrosine can be deiodinated (Xenopus tropicalis)


name: Autocleavage of ESPL1 (Separase) (Caenorhabditis elegans)


name: FANCM:FAAP24 and APITD1:STRA13 bind ICL-DNA (Homo sapiens)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Danio rerio)


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: EXT1:EXT2 transfers GlcA to heparan (Danio rerio)


name: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O => (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Homo sapiens)


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Danio rerio)


name: Dissociation of  transcript with 5'-GMP from GT (Xenopus tropicalis)


name: gamma-L-glutamyl-L-cysteine + hercynine + O2 => gamma-L-glutamyl-hercynylcysteine S-oxide + H2O


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: carnosine(out) + H(+)(out) <=> carnosine(in) + H(+)(in)


name: RHOG binds effectors at the plasma membrane (Caenorhabditis elegans)


name: LDH tetramer reduces PYR to LACT (Xenopus tropicalis)


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Sus scrofa)


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Sus scrofa)


name: p62 recruits an atypical PKC (Sus scrofa)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Dictyostelium discoideum)


name: a 1,2-diacyl-sn-glycero-3-phosphoglycerol + H2O = a 1,2-diacyl-sn-glycerol + glycerol 1-phosphate + H(+)


name: a long-chain fatty acid(in) + ATP + H2O <=> a long-chain fatty acid(out) + ADP + H(+) + phosphate


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Danio rerio)


name: Ligand-independent dimerization of point mutants of ALK (Homo sapiens)


name: P2Y14 receptor can bind to UDP-glucose (Homo sapiens)


name: p-T,4S-IRF3 is dimerized (Rattus norvegicus)


name: H(+) + H2O + NAD(+) + rifampicin para-naphthoquinone carboxamide => NADH + O2 + rifampicin


name: AMP + diphosphate + propanoyl-CoA => ATP + CoA + propanoate


name: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO2 + CoA


name: Expression of FOXF1 in lateral plate mesoderm (Homo sapiens)


name: Formation of FACT complex (Homo sapiens)


name: PRLR binds SCF beta-TrCP complex (Homo sapiens)


name: MMACHC:cob(II)alamin binds MMADHC (Mus musculus)


name: Phosphorylation and activation of CHEK2 by ATM (Canis familiaris)


name: 6-oxohexanoate + H2O + NADP(+) = 2 H(+) + hexanedioate + NADPH


name: SLC25A18,22 import L-Glu, H+ (Drosophila melanogaster)


name: GLYCTK phosphorylates DGA to 3PDGA (Rattus norvegicus)


name: Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA (Xenopus tropicalis)


name: decanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 10-hydroxydecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RNA Polymerase III Transcriptional Pause at Terminator Sequence (Homo sapiens)


name: 3beta-hydroxyandrost-5-en-17-one + acetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17alpha-hydroxypregnenolone + O2 + reduced [NADPH--hemoprotein reductase]


name: DNA ligase I ligates single stranded nick in double stranded DNA (Homo sapiens)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Plasmodium falciparum)


name: 2-dehydro-3-deoxy-D-gluconate + NAD(+) <=> 3-deoxy-D-glycero-2,5-hexodiulosonate + H(+) + NADH


name: choline => acetaldehyde + trimethylamine


name: S1P hydrolyzes SREBP1A,1C,2 (Drosophila melanogaster)


name: ATP + holo-[ACP] + octanoate => AMP + diphosphate + octanoyl-[ACP]


name: a fatty acid + H(+) + sn-glycerol 3-phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine + H2O


name: Factor H displaces Bb (Xenopus tropicalis)


name: 3'-N-debenzoyltaxol + benzoyl-CoA <=> CoA + H(+) + taxol


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Xenopus tropicalis)


name: O2 + peregrinol + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADPH + pent-1-en-3-one => NADP(+) + pentan-3-one


name: 4-hydroxyestrone + S-adenosyl-L-methionine <=> 4-methoxyestrone + H(+) + S-adenosyl-L-homocysteine


name: (1S,5R)-carveol + NAD(+) <=> (R)-carvone + H(+) + NADH


name: SRD5A1 dehydrogenates TEST to DHTEST (Homo sapiens)


name: Ubiquitinated Cdc6 is degraded by the proteasome (Saccharomyces cerevisiae)


name: H2O + methanethiol + O2 <=> formaldehyde + H(+) + H2O2 + hydrogen sulfide


name: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate


name: NUDT12 hydrolyses NADH to NMNH (Rattus norvegicus)


name: 2-methyl-L-serine = formaldehyde + L-alanine


name: ADP + cholesterol(out) + H(+) + phosphate => ATP + cholesterol(in) + H2O


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MAP2K1 phosphorylates MAPK3 (Saccharomyces cerevisiae)


name: 4-oxocyclohexane-1-carboxylate + H(+) + NADH => NAD(+) + trans-4-hydroxycyclohexane-1-carboxylate


name: a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+) => a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol


name: Translocation of BIM to mitochondria (Rattus norvegicus)


name: (2E)-geranyl diphosphate + H2O <=> (R)-alpha-terpineol + diphosphate


name: ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)


name: IL12A:IL12B translocates from late endosome lumen to extracellular region (Bos taurus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Danio rerio)


name: 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+) => 2,3-dihydroxybenzoate + O2


name: 2-oxoglutarate + L-aspartyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: 1D-myo-inositol 2,4,5-triphosphate + H2O <=> 1D-myo-inositol 2,5-bisphosphate + phosphate


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Mus musculus)


name: N(2)-(1-hydroxy-2-oxopropyl)-GDP => GDP + methylglyoxal


name: D-xylulose 5-phosphate => L-ribulose 5-phosphate


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Caenorhabditis elegans)


name: PDPK1 binds PIP3 (Plasmodium falciparum)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Homo sapiens)


name: SAR1 Activation And Membrane Binding (Drosophila melanogaster)


name: 24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Schizosaccharomyces pombe)


name: 5,10-dihydrophenazine + CO2 + H2O2 => (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + H(+) + O2


name: ATP + D-mannose = ADP + D-mannose 6-phosphate + H(+)


name: XYLTs transfer Xyl to core protein (Sus scrofa)


name: CDP-DAG is converted to PI by CDIPT (Dictyostelium discoideum)


name: Nuclear translocation of catalytic domain of Mst3 (Xenopus tropicalis)


name: ATP + L-glutamate + tRNA(Glu) => AMP + diphosphate + L-glutamyl-tRNA(Glu)


name: IL31:IL31RA:JAK1 binds OSMR:JAK1 (Mus musculus)


name: aldehydo-D-glucuronate(in) + H(+)(in) = aldehydo-D-glucuronate(out) + H(+)(out)


name: alpha-maltotetraose + phosphate => alpha-D-glucose 1-phosphate + alpha-maltotriose