name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Rattus norvegicus)


name: 1D-myo-inositol 1,3-bisphosphate + H2O <=> 1D-myo-inositol 1-phosphate + phosphate


name: 3'-phosphoadenylyl sulfate + cholate => adenosine 3',5'-bisphosphate + cholate 7-sulfate + H(+)


name: (9Z)-octadecenoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol = 1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: Cleavage of DFF45 (224) by caspase-3 (Canis familiaris)


name: betaenone C + H(+) + NADPH + O2 <=> H2O + NADP(+) + stemphyloxin I


name: chloride(in) + formate(out) => chloride(out) + formate(in)


name: D-maltotetraose + H2O <=> alpha-D-glucose + D-maltotriose


name: 2 Fe(III)-[cytochrome c] + S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate => 2 Fe(II)-[cytochrome c] + 2 H(+) + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein]


name: SLP-76 stimulates PLC gamma 2 (Dictyostelium discoideum)


name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Canis familiaris)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Gallus gallus)


name: estrone 3-sulfate(out) + succinate(in) = estrone 3-sulfate(in) + succinate(out)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Sus scrofa)


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Homo sapiens)


name: (R)-carnitine(in) + O-acyl-(R)-carnitine(out) => (R)-carnitine(out) + O-acyl-(R)-carnitine(in)


name: H2O + O2 + pyridoxal = 4-pyridoxate + H(+) + H2O2


name: H(+)(out) + homoserine lactone(in) => H(+)(in) + homoserine lactone(out)


name: an alcohol + H2O + NAD(+) => a hydroperoxide + H(+) + NADH


name: H(+) + L-xylo-3-hexulose + NADPH => D-sorbitol + NADP(+)


name: a menaquinol + nitrate => a menaquinone + H2O + nitrite


name: (4R)-ipsdienol + NADP(+) <=> H(+) + ipsdienone + NADPH


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Saccharomyces cerevisiae)


name: glycerol 2-phosphate + H2O = glycerol + phosphate


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-GlcNAc + GDP-beta-L-fucose <=> alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-GlcNAc + GDP + H(+)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Drosophila melanogaster)


name: 2-oxoglutarate + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate = L-2-acetamido-6-oxoheptanedioate + L-glutamate


name: VRK1/VRK2 phosphorylate BANF1 (Homo sapiens)


name: Autophosphorylation of PDGF beta receptors (Gallus gallus)


name: [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine


name: histamine + S-adenosyl-L-methionine = H(+) + N(tau)-methylhistamine + S-adenosyl-L-homocysteine


name: lithocholate + NAD(+) <=> 3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: ABCB1 transports PREDN,PREDL out of kidney cells (Sus scrofa)


name: 2xPPCS ligates PPanK with Cys (Xenopus tropicalis)


name: Co(I)-[methylamine-specific corrinoid protein] + H(+) + methylamine => methyl-Co(III)-[methylamine-specific corrinoid protein] + NH4(+)


name: 4-methylnorajmaline + S-adenosyl-L-methionine <=> 4-methylajmaline + H(+) + S-adenosyl-L-homocysteine


name: (22S)-22-hydroxycampest-4-en-3-one + O2 + reduced [NADPH--hemoprotein reductase] <=> (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NAD(+) + pregnenolone => H(+) + NADH + pregn-5-ene-3,20-dione


name: (1S,2S)-pseudoephedrine + NAD(+) <=> (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: Recruitment of Grb2 to pFAK:NCAM1 (Canis familiaris)


name: (indol-3-yl)acetate + NH4(+) => (indol-3-yl)acetonitrile + 2 H2O


name: Syk activation leads to SLP-76 activation (Canis familiaris)


name: ATR phosphorylates TP53 (Rattus norvegicus)


name: an N-acyl-D-mannosamine + ATP => ADP + an N-acyl-D-mannosamine 6-phosphate + H(+)


name: CREBBP acetylates HINT1 dimer (Homo sapiens)


name: an aldehyde + H(+) + NADH => a primary alcohol + NAD(+)


name: H(+) + malonyl-CoA + tetracosanoyl-CoA = 3-oxohexacosanoyl-CoA + CO2 + CoA


name: (9Z,12Z)-octadecadienoate + O2 <=> (8E,10R,12Z)-10-hydroperoxyoctadeca-8,12-dienoate


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Plasmodium falciparum)


name: CO2 + deoxyviolacein + 2 H2O + NADP(+) => 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate


name: 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Rattus norvegicus)


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Homo sapiens)


name: ATAT acetylates microtubules (Bos taurus)


name: OCT1 transports organic cations out of hepatic cells (Caenorhabditis elegans)


name: a (Z)-N-(sulfonatooxy)alkenimidothioate + D-glucose + H(+) => a (Z)-alkenyl glucosinolate + H2O


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Drosophila melanogaster)


name: TRIP11:IFT20 dissociates (Drosophila melanogaster)


name: RUNX3 translocates to the nucleus (Caenorhabditis elegans)


name: 3,4-dihydroxybenzoate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] => 3-hydroxy-4-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: Factor D cleaves C3b-bound Factor B (Danio rerio)


name: 3-phenylpropanal + L-alanine => 3-phenylpropylamine + pyruvate


name: H2O + N-(11Z-eicosenoyl)-sphinganine => (11Z)-eicosenoate + sphinganine


name: Activated FGFR1 binds FLRT1,2,3 (Canis familiaris)


name: L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: a (2S,3S)-flavan-3-ol + 2 NADP(+) <=> an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH


name: AH2 + prostaglandin G3 => A + H2O + prostaglandin H3


name: 3'-dephospho-CoA + a 5'-end phospho-ribonucleoside in mRNA + H(+) => a 5'-end CoA-ribonucleoside in mRNA + H2O


name: L-methionine + tetrahydropteroyltri-L-glutamate => 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine


name: SLC29A1 transports RBV from extracellular region to cytosol (Dictyostelium discoideum)


name: GTP + UTP = 3',3'-cGMP-UMP + 2 diphosphate


name: 3-oxododecanoyl-CoA + H(+) + NADH => (3R)-3-hydroxydodecanoyl-CoA + NAD(+)


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Drosophila melanogaster)


name: (3R)-3-amino-3-phenylpropanoyl-CoA + baccatin III = 3'-N-debenzoyl-2'-deoxytaxol + CoA


name: (2E,6E)-farnesyl diphosphate <=> beta-cadinene + diphosphate


name: sn-glycerol 3-phosphate + tetradecanoyl-CoA <=> 1-tetradecanoyl-sn-glycerol 3-phosphate + CoA


name: (9Z)-octadecenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphate => 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Danio rerio)


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Canis familiaris)


name: RAB1:GTP recruits GBF1 to the ERGIC (Bos taurus)


name: 12,13-epoxy-(9Z)-octadecenoate + H2O <=> 12,13-dihydroxy-(9Z)-octadecenoate


name: GSDMD (1-275) binds cardiolipin (Homo sapiens)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + H(+) + malonyl-CoA = (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + CoA


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: Proteasome mediated degradation of COP1 (Bos taurus)


name: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Homo sapiens)


name: SLC26A3,6 exchange Cl- for HCO3- (Homo sapiens)


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Sus scrofa)


name: phosphate + pyridoxal => H2O + pyridoxal 5'-phosphate


name: NLRP3 activation by small molecules (Mus musculus)


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O => 2-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: 4-chlorobenzoyl-CoA + chloride + NADP(+) => 2,4-dichlorobenzoyl-CoA + NADPH


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Drosophila melanogaster)


name: BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV (Drosophila melanogaster)


name: 2 H(+) + roseoflavin + 2 S-adenosyl-L-homocysteine => 8-amino-8-demethylriboflavin + 2 S-adenosyl-L-methionine


name: Phosphorylation of CRMPs by Cdk5 (Bos taurus)


name: 6-demethylmitomycin B + S-adenosyl-L-methionine = mitomycin B + S-adenosyl-L-homocysteine


name: PPA2A dephosphorylates SPRY2 (Homo sapiens)


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Homo sapiens)


name: cholate + L-serine <=> H2O + L-serocholate


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Rattus norvegicus)


name: 8-methylmenaquinol-6 + fumarate => 8-methylmenaquinone-6 + succinate


name: Multi-ubiquitination of APOBEC3G (Homo sapiens)


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H(+) + NADH => 4-pyridoxate + NAD(+)


name: DAAM1 recruits GTP-bound RHOA (Caenorhabditis elegans)


name: H(+) + N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine => L-histidyl-[protein] + S-adenosyl-L-methionine


name: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity


name: nicotinic acid riboside hydrolase activity


name: Formation of FACT complex (Rattus norvegicus)


name: HEY1 gene expression is positively regulated by NOTCH3 and STAT1 (Homo sapiens)


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Dictyostelium discoideum)


name: 17beta-estradiol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 19-oxotestosterone + O2 + reduced [NADPH--hemoprotein reductase]


name: LIPs hydrolyze TG to DAG and LCFA (Canis familiaris)


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Homo sapiens)


name: UROS transforms HMB to URO3 (Sus scrofa)


name: TFAP2C homodimer binds MYC and KDM5B (Danio rerio)


name: B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD (Xenopus tropicalis)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 => (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate


name: a D-galactosylceramide + H(+) + UDP => an N-acyl-sphingoid base + UDP-alpha-D-galactose


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) <=> 5,7-dihydroxy-4-methylphthalide + H2O


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Danio rerio)


name: (2S)-2-methylbutanenitrile + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylbutanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Ligand-independent dimerization of FLT3 fusion proteins (Homo sapiens)


name: ZNRF3 autoubiquitinates to promote its internalization (Bos taurus)


name: SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)


name: TP53 and CREBBP bind BNIP3L gene (Homo sapiens)


name: ATP + taurocyamine => ADP + H(+) + N-phosphotaurocyamine


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine <=> 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate


name: Dissociation of the P2Y purinoceptor 1:Gq complex (Sus scrofa)


name: 20-hydroxy prostaglandin A1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + prostaglandin A1 + reduced [NADPH--hemoprotein reductase]


name: a ketone + H(+) + NADPH => a secondary alcohol + NADP(+)


name: ADP(in) + FAD(out) <=> ADP(out) + FAD(in)


name: Receptor CCR7 binds CCL19 and 21 ligands (Danio rerio)


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Xenopus tropicalis)


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Gallus gallus)


name: Insertion of correct bases opposite the lesion by POLH (Drosophila melanogaster)


name: 2-oxoglutarate + melatonin + O2 = 2-hydroxymelatonin + CO2 + succinate


name: p-Y389,400-RUFY1 binds PI3P (Bos taurus)


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Schizosaccharomyces pombe)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Drosophila melanogaster)


name: Interaction of Bcl10 to CARMA1 (Homo sapiens)


name: ALPI dimer hydrolyses phosphate monoesters (Drosophila melanogaster)


name: POU5F1 (OCT4), SOX2, NANOG bind the EOMES promoter (Homo sapiens)


name: SLC22A13 transports NCA from extracellular region to cytosol (Mus musculus)


name: PDCD1 binds PDCD1 inhibitors (Bos taurus)


name: CYSLT2 binds LTC4,LTD4,LTE4 (Bos taurus)


name: dTMP + H2O => 2-deoxy-D-ribose 5-phosphate + thymine


name: GNRHR binds chemical antagonists (Danio rerio)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH => deoxycholate + NADP(+)


name: an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose = an alpha-D-mannosylinositol-1-phosphodihydroceramide + GDP + H(+)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Drosophila melanogaster)


name: Recognition and Binding of Core Promoter Elements by TFIID (Canis familiaris)


name: MECP2 T158A:SIN3A complex does not bind BDNF gene promoter (Homo sapiens)


name: L-ascorbate(out) + 2 Na(+)(out) = L-ascorbate(in) + 2 Na(+)(in)


name: H2O + L-lysine + O2 <=> 6-amino-2-oxohexanoate + H2O2 + NH4(+)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: ADP + coproporphyrin I(out) + H(+) + phosphate => ATP + coproporphyrin I(in) + H2O


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + H2O = 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H(+)


name: Kazrin binds periplakin (Rattus norvegicus)


name: cAMP dissociates PKA, promoting GLI processing (Bos taurus)


name: SRD5A2 binds SRD5A2 inhibitors (Canis familiaris)


name: 4alpha-carboxyzymosterol + NAD(+) = CO2 + NADH + zymosterone


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Gallus gallus)


name: (2E)-hexenoyl-CoA + H2O => (3S)-hydroxyhexanoyl-CoA


name: H2O + N-hexadecanoyl-L-phenylalanine <=> hexadecanoate + L-phenylalanine


name: CTP(out) + dCMP(in) => CTP(in) + dCMP(out)


name: p-S133-CREB1 binds MITF promoter (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol <=> 2-hexadecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl hexadecanoate


name: 13-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate


name: beta-muricholoyl-CoA + lithocholate => beta-muricholate + lithocholoyl-CoA


name: 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Bos taurus)


name: Displacement of C2a/Bb by CR1 (Homo sapiens)


name: YAP1 binds TEAD3 (Caenorhabditis elegans)


name: (S)-2-ureidoglycine + H2O = glyoxylate + NH4(+) + urea


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Caenorhabditis elegans)


name: benzylmalonyl-CoA + H(+) + O2 <=> (E)-cinnamoyl-CoA + CO2 + H2O2


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Rattus norvegicus)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Drosophila melanogaster)


name: 2,5-dioxopentanoate + H2O + NAD(+) = 2-oxoglutarate + 2 H(+) + NADH


name: N-acyl-15-methylhexadecasphing-4-enine + UDP-alpha-D-glucose <=> H(+) + N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine + UDP


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Sus scrofa)


name: 2 2-iminio-3-(indol-3-yl)propanoate + H2O2 => chromopyrrolate + H(+) + 2 H2O + NH4(+)


name: C-terminal L-cysteinyl-[HypE protein] + carbamoyl adenylate => AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + H(+)


name: CYP26A1,B1,C1 4-hydroxylate atRA (Gallus gallus)


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Bos taurus)


name: DHFR dimer reduces FOLA to DHF (Saccharomyces cerevisiae)


name: H2O + phosphoenolpyruvate => (2R)-2-phosphoglycerate


name: [(3R)-hydroxybutanoate](n) + H2O => (R)-3-hydroxybutanoate + [(3R)-hydroxybutanoate](n-1) + H(+)


name: (1S,5R)-carveol + NAD(+) = (R)-carvone + H(+) + NADH


name: Active FLT3:GRB2 binds SOS1 (Sus scrofa)


name: acetyl-CoA + citramalate => (3S)-citramalyl-CoA + acetate


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Canis familiaris)


name: L-alanine + succinate semialdehyde => 4-aminobutanoate + pyruvate


name: TFIIS-mediated recovery of elongation from arrest (Drosophila melanogaster)


name: Mad1 binds kinetochore (Canis familiaris)


name: CARKD dehydrates S-NAD(P)HX to NADPH (Canis familiaris)


name: cytidine(out) + Na(+)(out) <=> cytidine(in) + Na(+)(in)


name: 3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] => 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite


name: H2O + L-lysine + NAD(+) => (S)-2-amino-6-oxohexanoate + H(+) + NADH + NH4(+)


name: H2O + NADP(+) <=> ADP-D-ribose 2'-phosphate + H(+) + nicotinamide


name: Association of procollagen type XVI (Homo sapiens)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 => (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: ent-copalyl diphosphate + H2O <=> diphosphate + ent-manool


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Dictyostelium discoideum)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A = a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate)


name: 1,2-dihydro-alpha-santonin + NAD(+) => alpha-santonin + H(+) + NADH


name: RHOB binds effectors at the plasma membrane (Rattus norvegicus)


name: HSD17B13 binds lipid droplets (Homo sapiens)


name: hexadecane-1,16-diol + O2 <=> H2O2 + hydroxyhexadecanal


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Drosophila melanogaster)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Bos taurus)


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Mus musculus)


name: 2 H(+) + L-pyrrolysine + NADH + NH4(+) => (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + NAD(+)


name: H2O + L-glutamate 5-semialdehyde + NADP(+) => 2 H(+) + L-glutamate + NADPH


name: Release of platelet cytosolic components (Rattus norvegicus)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Dictyostelium discoideum)


name: H2O + N(6)-malonyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-malonyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: YWHAB dimer dissociates from dephosphorylated RAF (Rattus norvegicus)


name: glycine betaine + 3 H(+) + 3 S-adenosyl-L-homocysteine => glycine + 3 S-adenosyl-L-methionine


name: SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Danio rerio)


name: Phosphorylated heterodimers of ERBB2 TMD/JMD mutants recruit GRB2:SOS1 through SHC1 (Homo sapiens)


name: factor VII -> factor VIIa (Rattus norvegicus)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Saccharomyces cerevisiae)


name: 2 benzoyl-CoA + L-ornithine => 2 CoA + 2 H(+) + N(2),N(5)-dibenzoyl-L-ornithine


name: Formation of Classical C3 convertase (C4b:C2a complex) (Sus scrofa)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Schizosaccharomyces pombe)


name: Coumarin is 7-hydroxylated by CYP2A6 (Sus scrofa)


name: RHOB GAPs stimulate RHOB GTPase activity (Xenopus tropicalis)


name: 4-hydroxybenzoate + 2 H(+) + NADPH => 4-hydroxybenzaldehyde + H2O + NADP(+)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + soyasapogenol B => O2 + reduced [NADPH--hemoprotein reductase] + sophoradiol


name: AKT phosphorylates CREB1 (Caenorhabditis elegans)


name: sphinganine 1-phosphate => hexadecanal + phosphoethanolamine


name: PTPRZ dephosphorylates ligand-bound ALK dimers (Sus scrofa)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Rattus norvegicus)


name: H(+)(in) + L-alanyl-D-glutamate(in) => H(+)(out) + L-alanyl-D-glutamate(out)


name: L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine


name: ADP + H(+) + N(5)-methyl-L-glutamine + phosphate => ATP + L-glutamate + methylamine


name: dynorphin A-(1-13) + H2O => dynorphin A-(1-12) + L-lysine


name: sugar transmembrane transporter activity


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Drosophila melanogaster)


name: 1-O-(alk-1-enyl)-sn-glycero-3-phosphate + H2O = 1-O-(alk-1-enyl)-sn-glycerol + phosphate


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Sus scrofa)


name: acetyl-CoA + gentamicin C1a <=> CoA + H(+) + N(2')-acetylgentamicin C1a


name: Formation of MSH1:PMS2 Complex (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + sphing-4-enine => H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sphing-4-enine


name: RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)


name: PTP-RO interacts with p-c-Kit complex (Danio rerio)


name: RHOB GEFs activate RHOB (Drosophila melanogaster)


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate => alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: 2 H2O + ricinine => 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate + NH4(+)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)


name: ITP + pyruvate = H(+) + IDP + phosphoenolpyruvate


name: 4 Fe(II)-[cytochrome c] + 5 H(+) + L-dehydroascorbate => 4 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone


name: AH2 + ATP + 2 Co(II)-[dimethylamine-specific corrinoid protein] + H2O = A + ADP + 2 Co(I)-[dimethylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Saccharomyces cerevisiae)


name: Localization of CBL:GRB2 to the membrane (Sus scrofa)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Caenorhabditis elegans)


name: (S)-cheilanthifoline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase]


name: hexadecasphinganine + octadecanoyl-CoA => CoA + H(+) + N-octadecanoylhexadecasphinganine


name: 32-oxo-24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase] = 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (indol-3-yl)butanoate + ATP + L-cysteine = (indol-3-yl)butanoyl-L-cysteine + AMP + diphosphate + H(+)


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Homo sapiens)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => diphosphate + fusoxypene A


name: 3,5,7-trioxododecanoyl-CoA <=> CoA + H(+) + olivetolate


name: 1-O-alkyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-alkyl-sn-glycerol + H(+) + phosphocholine


name: Autophosphorylation of SRC (Gallus gallus)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active ALK dimer binds IRS1 (Homo sapiens)


name: CTLH E3 ligase ubiquitinates LDHA (Bos taurus)


name: Dehalogenation of carbon tetrachloride to form a free radical (Canis familiaris)


name: (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(in) + ATP + H2O => (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(out) + ADP + H(+) + phosphate


name: (3R)-hydroxy-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA = (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H2O


name: D-tryptophan + O2 = N-formyl-D-kynurenine


name: H(+)(out) + spermidine(in) => H(+)(in) + spermidine(out)


name: Caspase-mediated cleavage of plakophilin-1 (Homo sapiens)


name: RHOU binds effectors at the plasma membrane (Gallus gallus)


name: ATP + L-glutamate + tyramine => ADP + gamma-L-glutamyltyramine + H(+) + phosphate


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 2-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-lysine + NAD(+) => 2 H(+) + L-1-piperideine-6-carboxylate + NADH + NH4(+)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Gallus gallus)


name: acetyl-CoA + an alkane-alpha,omega-diamine => an N-acetylalkane-alpha,omega-diamine + CoA + H(+)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Homo sapiens)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Sus scrofa)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Caenorhabditis elegans)


name: FOLR2 transports FOLA from extracellular region to cytosol (Danio rerio)


name: (9Z,12Z)-octadecadienoyl-CoA + H(+) + malonyl-CoA <=> (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA


name: Activated FGFR3 phosphorylates FRS2 (Drosophila melanogaster)


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Homo sapiens)


name: Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Mus musculus)


name: L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: PVR:PVRL3 trans heterodimer interaction (Canis familiaris)


name: MLKL binds FLOT1, FLOT2 (Rattus norvegicus)


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Schizosaccharomyces pombe)


name: Enzyme-bound ATP is released (Mus musculus)


name: Aquaporin-3 passively transports water out of cell (Danio rerio)


name: NPAS4 binds ARNTL (BMAL1) (Xenopus tropicalis)


name: ADRM1 binds 26S proteasome (Schizosaccharomyces pombe)


name: SOX10, POU3F1 and POU3F2 bind EGR2 gene (Homo sapiens)


name: Cho is acetylated to AcCho by CHAT (Bos taurus)


name: CYGB:O2 dissociates (Caenorhabditis elegans)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Gallus gallus)


name: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine <=> an N(6)-methyl-2'-O-methyladenosine in U2 snRNA + H(+) + S-adenosyl-L-homocysteine


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Gallus gallus)


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Homo sapiens)


name: 1-acyl LPE is acylated to PE by LPEAT (Caenorhabditis elegans)


name: Phosphorylation of Syntaxin-4 (Dictyostelium discoideum)


name: TLR folding by chaperones GP96 and CNPY3 (Mus musculus)


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Canis familiaris)


name: 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Sus scrofa)


name: H(+) + NADH + O2 + theobromine => 7-methylxanthine + formaldehyde + H2O + NAD(+)


name: ITGA4:ITGB1 binds natalizumab (Homo sapiens)


name: ICMT methylates S-Farn RAS proteins (Gallus gallus)


name: 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Sus scrofa)


name: 3-oxo-(7Z-hexadecenoyl)-CoA + CoA => (5Z)-tetradecenoyl-CoA + acetyl-CoA


name: IL6ST is tyrosine phosphorylated (Gallus gallus)


name: (2E)-geranyl diphosphate + umbelliferone => 8-geranylumbelliferone + diphosphate


name: lathosterol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha,8alpha-epoxy-5alpha-cholestan-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IL10 dimer binds IL10RA:JAK1 (Bos taurus)


name: (1S,4S)-5-oxo-1,2-campholide => [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)


name: (20R)-20-hydroxypregn-4-en-3-one + NAD(+) = H(+) + NADH + progesterone


name: dihydromonacolin L-[lovastatin nonaketide synthase] + H2O <=> dihydromonacolin L carboxylate + H(+) + holo-[lovastatin nonaketide synthase]


name: GGCT transforms gGluCys to OPRO (Canis familiaris)


name: SCF(SKP2) complex binds RUNX2 (Homo sapiens)


name: beta-nicotinamide D-ribonucleotide + H2O <=> NH4(+) + nicotinate beta-D-ribonucleotide


name: a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-homocysteine


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H(+)


name: HILPDA binds lipid droplets (Homo sapiens)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Bos taurus)


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-uridine-RNA => ribonucleotidyl-uridine-RNA


name: DMBT1 binds SFTPD 12mer, SFTPAs (Danio rerio)


name: beta-alanyl-[peptidyl-carrier protein] + tryptamine <=> beta-alanyl-tryptamine + H(+) + holo-[peptidyl-carrier protein]


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Homo sapiens)


name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Danio rerio)


name: SUMOylation of PCNA with SUMO1 (Bos taurus)


name: Bcl-2 and Bcl-XL bind NLRP1 (Gallus gallus)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Canis familiaris)


name: Activated NTRK3 promotes SRC autophosphorylation (Rattus norvegicus)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Bos taurus)


name: (2E)-geranyl diphosphate => (1S,5S)-beta-pinene + diphosphate


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Sus scrofa)


name: NEXT1 PEST domain mutants are cleaved to produce NICD1 PEST domain mutants (Homo sapiens)


name: NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Gallus gallus)


name: NDUF subunits bind to form the IP subcomplex (Caenorhabditis elegans)


name: ADP + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] <=> AMP + H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase]


name: Defective SLC37A4 does not exchange G6P and Pi across the ER membrane (Homo sapiens)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Xenopus tropicalis)


name: PLC gamma 2-mediated PIP2 hydrolysis (Rattus norvegicus)


name: RAC1 GDIs block activation of RAC1 (Rattus norvegicus)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Danio rerio)


name: Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Gallus gallus)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Rattus norvegicus)


name: Recruitment of Spike trimer to assembling virion (Homo sapiens)


name: CASR binds CASR agonists (Rattus norvegicus)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Caenorhabditis elegans)


name: 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + 6 CO2 + 7 CoA + H2O => acetyl-CoA + 5 H(+) + 6 malonyl-CoA


name: H2O + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2) => beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: L-allo-threonine <=> acetaldehyde + glycine


name: resolvin E1 => (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: 1D-myo-inositol hexakisphosphate + ATP <=> 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP


name: 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: OTUD3 deubiquitinates PTEN (Mus musculus)


name: a 5'-end 5'-phospho-ribonucleoside-RNA + H2O => a 5'-end dephospho-ribonucleoside-RNA + phosphate


name: 4-hydroxyphenylacetyl-CoA + H2O = 4-hydroxyphenylacetate + CoA + H(+)


name: PP1 binds to phosphorylated TIM (Drosophila melanogaster)


name: 7,8-dihydrofolate + ATP + formate <=> 10-formyldihydrofolate + ADP + phosphate


name: H2O + N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine = 4-amino-5-aminomethyl-2-methylpyrimidine + formate


name: a sterol ester + H2O => a fatty acid + a sterol + H(+)


name: a 2-acylphloroglucinol 1-O-beta-D-glucoside + UDP => a 2-acylphloroglucinol + UDP-alpha-D-glucose


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Xenopus tropicalis)


name: ARL2:GTP bind PDE6D on KRAS4B (Drosophila melanogaster)


name: a dipeptide(in) + H(+)(in) => a dipeptide(out) + H(+)(out)


name: Translocation of ERBB4s80 to the nucleus (Xenopus tropicalis)


name: ZBED1 (DREF) SUMOylates CHD3 with SUMO1 (Sus scrofa)


name: NAT1,2 acetylate APAP-Cys to APAP-Mer (Sus scrofa)


name: an N,N-dimethylornithine lipid + H(+) + S-adenosyl-L-homocysteine => an N-methylornithine lipid + S-adenosyl-L-methionine


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Homo sapiens)


name: Phosphorylation of USP8 by P-AKT (Rattus norvegicus)


name: 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine => beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc + H2O


name: 5,6-dihydrouridine(47) in tRNA + NADP(+) => H(+) + NADPH + uridine(47) in tRNA


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Xenopus tropicalis)


name: 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA => 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: ITPA hydrolyses ITP to IMP (Xenopus tropicalis)


name: ADP + an N(4)-acetylcytidine in 18S rRNA + CoA + H(+) + phosphate => a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O


name: PTGS1 dimer binds PTGS1 Inhibitors (Danio rerio)


name: NADP(+) + sphinganine <=> 3-oxosphinganine + H(+) + NADPH


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Mus musculus)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Schizosaccharomyces pombe)


name: dodecanoyl-[ACP] + H2O = dodecanoate + H(+) + holo-[ACP]


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Sus scrofa)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Gallus gallus)


name: Nuclear DUSPs dephosphorylate MAPKs (Dictyostelium discoideum)


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Saccharomyces cerevisiae)


name: ADP + H(+) + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) + phosphate => ATP + H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out)


name: racemase and epimerase activity, acting on hydroxy acids and derivatives


name: "Acting on hydroxy acids and derivatives"


name: mito-STARD7 transports Q10 to outer mitochondrial membrane (Drosophila melanogaster)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Gallus gallus)


name: 11-oxocucurbitadienol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => cucurbitadienol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels


name: ISGylation of protein translation regulator 4EHP (Homo sapiens)


name: Dissociation of RAS:RAF complex (Gallus gallus)


name: [protein-PII]-uridylyl-L-tyrosine + diphosphate => [protein-PII]-L-tyrosine + UTP


name: (R)-2-benzylsuccinate + succinyl-CoA => (R)-2-benzylsuccinyl-CoA + succinate


name: Formation of tonofilament bundles (Danio rerio)


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Sus scrofa)


name: p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol (Sus scrofa)


name: NADP(+) + octan-1-ol = H(+) + NADPH + octanal


name: PNPLA4 hydrolyzes retinyl palmitate (Canis familiaris)


name: (+)-dehydrodiconiferyl acid + 2 a quinone + H2O = (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Xenopus tropicalis)


name: Parkin binds Ub:UBE2N:UBE2V1 (Canis familiaris)


name: Luteinizing hormone receptor can bind LH (Mus musculus)


name: an L-alpha-amino acid + H2O + NAD(+) => a 2-oxocarboxylate + H(+) + NADH + NH4(+)


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Sus scrofa)


name: Fibronectin degradation by ADAM8 (Bos taurus)


name: Antizyme OAZ binds to Ornithine decarboxylase (Danio rerio)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Bos taurus)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Schizosaccharomyces pombe)


name: 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP => indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose


name: 3-methyl-2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = 2-methylpropanoyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Sus scrofa)


name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity


name: a quinone + H2O + methanol => a quinol + methane + O2


name: 19-oxo-androst-4-ene-3,17-dione + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 19-hydroxyandrost-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase]


name: 4-prenylphlorisovalerophenone + dimethylallyl diphosphate => deoxyhumulone + diphosphate


name: D-xylose + NADP(+) <=> D-xylono-1,5-lactone + H(+) + NADPH


name: Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 (Dictyostelium discoideum)


name: RAC1 and CDC42 activate PAK1 (Dictyostelium discoideum)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O <=> 1,2-diacyl-sn-glycero-3-phospho-L-serine-N-glycine + [protein]-C-terminal <stereo>L-</stereo>amino acid


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 17beta-estradiol 2-O-(beta-D-glucuronate) + H(+) + UDP


name: an alpha-L-fucoside + H2O => an alcohol + L-fucose


name: [(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose <=> [(1->4)-beta-D-glucosyl](n+1) + H(+) + UDP


name: mandelate + O2 <=> H2O2 + phenylglyoxylate


name: SPTLC complexes transfer acyl-CoA onto serine (Mus musculus)


name: (R)-5-phosphomevalonate + ATP = ADP + CO2 + isopentenyl phosphate + phosphate


name: a 1,2-diacyl-sn-glycero-3-phosphoglycerol + H2O <=> a 1,2-diacyl-sn-glycerol + glycerol 1-phosphate + H(+)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Homo sapiens)


name: a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphate => a 2'-deoxyribonucleoside 5'-triphosphate + H2O


name: Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Canis familiaris)


name: L-threonate + NAD(+) => 2-dehydro-L-erythronate + H(+) + NADH


name: KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Canis familiaris)


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Mus musculus)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + preaspterpenacid acid II => O2 + preaspterpenacid acid I + reduced [NADPH--hemoprotein reductase]


name: kaempferol + S-adenosyl-L-methionine => H(+) + kaempferol 7-methyl ether + S-adenosyl-L-homocysteine


name: PTP-RO interacts with p-c-Kit complex (Canis familiaris)


name: SETD6 methylates RELA in the NFkB complex (Homo sapiens)


name: Suicidal integration leading to inverted circle formation (Homo sapiens)


name: Oxoeicosanoid receptor can bind oxoeicosanoid (Homo sapiens)


name: CXXC1 and WDR82 bind SET1B complex (Bos taurus)


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,25-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ATP + H2O => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ADP + H(+) + phosphate


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Xenopus tropicalis)


name: Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Homo sapiens)


name: 4-(indol-3-yl)butanoyl-beta-D-glucose + UDP => (indol-3-yl)butanoate + UDP-alpha-D-glucose


name: The Ligand:GPCR:Gz complex dissociates (Homo sapiens)


name: H(+)(in) + L-ornithine(out) = H(+)(out) + L-ornithine(in)


name: Histidine is decarboxylated to histamine (Canis familiaris)


name: a ganglioside GD1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1b (d18:1(4E)) + CMP + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: endothelial differentiation G protein-coupled receptor binding


name: (E)-sinapate + cyanidin 3,5-di-O-beta-D-glucoside => 1-O-(trans-sinapoyl)-beta-D-glucose + cyanidin 3-O-beta-D-glucoside


name: EP1 receptor can bind PGE2 (Danio rerio)


name: Phosphorylation of IKK-beta by TAK1 (Sus scrofa)


name: 3,8,9,10-tetrahydroxy-6-methyl-1,4-dihydroanthracen-1-one + H(+) + NADPH <=> (3R)-3,8,9,10-tetrahydroxy-6-methyl-1,2,3,4-tetrahydroanthracen-1-one + NADP(+)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Homo sapiens)


name: USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Rattus norvegicus)


name: (3R)-hydroxy-(13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA => (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA + H2O


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) (Gallus gallus)


name: NPAS4 translocates to the cytosol (Homo sapiens)


name: Formation of the Flap Intermediate (Sus scrofa)


name: IL12B translocates from the cytosol to the extracellular region (Sus scrofa)


name: Glutamate synaptic vesicle docking and priming (Homo sapiens)


name: beta-D-mannopyranosyl-(1->2)-D-mannopyranose + phosphate => alpha-D-mannose 1-phosphate + D-mannose


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Gallus gallus)


name: 5,6,7,8-tetrahydrosarcinapterin + ADP + H(+) + phosphate => 5,6,7,8-tetrahydromethanopterin + ATP + L-glutamate


name: Binding of TFIIE to the growing preinitiation complex (Bos taurus)


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Canis familiaris)


name: protein tyrosine kinase collagen receptor activity


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Rattus norvegicus)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Rattus norvegicus)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: ALOX12 oxidises LTA4 to LXA4/B4 (Mus musculus)


name: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate => (2Z,6E,10E)-geranylgeranyl diphosphate + diphosphate


name: Prolactin-releasing hormone receptor binds PRH (Sus scrofa)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Sus scrofa)


name: a 3'-end 2'-deoxyribonucleotidyl-deoxyribonucleotide-DNA + H2O = a 2'-deoxyribonucleoside 5'-phosphate + a 3'-end 2'-deoxyribonucleotide-DNA + H(+)


name: 3-hydroxypropanal + H2O + NADP(+) = 3-hydroxypropanoate + 2 H(+) + NADPH


name: UDP-glucose is oxidised to UDP-glucuronate (Danio rerio)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Dictyostelium discoideum)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Drosophila melanogaster)


name: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid (Mus musculus)


name: dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Danio rerio)


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Gallus gallus)


name: CHGA-derived peptide binds the bacterial cell surface (Xenopus tropicalis)


name: ATP + streptomycin => 6-O-adenylylstreptomycin + diphosphate


name: 2-AG hydrolysis to arachidonate by MAGL (Plasmodium falciparum)


name: CRHR1,CRHR2-1 binds CRH,UCN (Mus musculus)


name: heme b + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => biliverdin IXalpha + CO + Fe(2+) + H(+) + 3 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: NADP(+) + pentan-3-one = H(+) + NADPH + pent-1-en-3-one


name: alpha-D-glucose 1-phosphate + H2O <=> D-glucose + phosphate


name: Light stimulates opsin receptors (Sus scrofa)


name: (S)-3-methyl-2-oxopentanoate + CoA + NAD(+) = 2-methylbutanoyl-CoA + CO2 + NADH


name: Parkin transfers Ub to misfolded proteins (Rattus norvegicus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 => 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Caenorhabditis elegans)


name: FarC-PTP4A2 binds RABGGTB (Plasmodium falciparum)


name: Mitochondrial uptake of (R)-3-aminoisobutyric acid (Homo sapiens)


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Sus scrofa)


name: an anthocyanidin 3-O-beta-D-glucoside + UDP => an anthocyanidin + H(+) + UDP-alpha-D-glucose


name: Gab2 binds the p85 subunit of Class 1A PI3 kinases (Gallus gallus)


name: H(+) + NADPH + thymine => 5,6-dihydrothymine + NADP(+)


name: H2O + N,1-diacyl-sn-glycero-3-phosphoethanolamine = a fatty acid + H(+) + N-acyl-sn-glycero-3-phosphoethanolamine


name: Autocatalytic phosphorylation of FGFR2b (Danio rerio)


name: PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)


name: Guanine + H2O => Xanthine + NH4+ (Sus scrofa)


name: 27-hydroxysterol binds ESR1, ESR2 (Drosophila melanogaster)


name: SDHAF4 binds to FAD-SDHA (Dictyostelium discoideum)


name: K+-independent Li+/Ca2+ exchanger transport (Bos taurus)


name: CoA + nonanoyl-AMP <=> AMP + H(+) + nonanoyl-CoA


name: P2Y14 receptor can bind to UDP-glucose (Gallus gallus)


name: CPTP transports C1P from plasma membrane to Golgi membrane (Canis familiaris)


name: IL12 bound to IL12R internalises (Bos taurus)


name: ATM phosphorylates HERC2 (Gallus gallus)


name: 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate => H(+) + homogentisate + phytyl diphosphate


name: p-T774-PKN1 phosphorylates CDC25C (Canis familiaris)


name: KIT binds type II TKIs (Drosophila melanogaster)


name: Active ALK phosphorylates IRS1 (Homo sapiens)


name: 3-methyl fatty acid + ATP + CoA <=> a 3-methyl fatty acyl-CoA + AMP + diphosphate


name: HRH2 binds HRH2 antagonists (Xenopus tropicalis)


name: RNF144A polyubiquitinates PRKDC (Homo sapiens)


name: PP2A methylation by LCMT1 (Caenorhabditis elegans)


name: ATP + O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein] = diphosphate + O-[5'-(adenylyl-(5'->3')-adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein]


name: Formation of COPII vesicle (Canis familiaris)


name: ARHGAP35 stimulates RHOA GTPase activity (Homo sapiens)


name: Dissociation of the Gi alpha:G olf complex (Xenopus tropicalis)


name: (S)-carvone + AH2 => (1R,4S)-isodihydrocarvone + A


name: Autophosphorylation of BTK/ITK (Homo sapiens)


name: O2 + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H2O2


name: (R)-3-hydroxybutanoate(out) + 2 Na(+)(out) = (R)-3-hydroxybutanoate(in) + 2 Na(+)(in)


name: Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Homo sapiens)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Danio rerio)


name: catechol + chloride + CO2 + NAD(+) => 2-chlorobenzoate + H(+) + NADH + O2


name: ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex (Mus musculus)


name: (4R)-hydroxysphinganine + hexacosanoate => H2O + N-hexacosanoyl-(4R)-hydroxysphinganine


name: (2E)-octenoyl-[ACP] + H(+) + NADPH => NADP(+) + octanoyl-[ACP]


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Homo sapiens)


name: 3-oxohexanoyl-[ACP] + CO2 + holo-[ACP] => butanoyl-[ACP] + H(+) + malonyl-[ACP]


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Mus musculus)


name: an n-alkanal + NADP(+) => an alk-2-enal + H(+) + NADPH


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Homo sapiens)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine


name: short-chain fatty acid transmembrane transporter activity


name: Expression of Stress-70 protein, mitochondrial (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate + H(+)


name: p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN (Homo sapiens)


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Mus musculus)


name: AH2 + isoquinolin-1(2H)-one => A + H2O + isoquinoline


name: (2E,6E)-farnesyl diphosphate => (-)-alpha-cedrene + diphosphate


name: coenzyme M + methanethiol <=> H(+) + hydrogen sulfide + methyl-coenzyme M


name: Inactive G alpha (q) reassociates with G beta:gamma (Caenorhabditis elegans)


name: Beta-catenin translocates to the nucleus (Homo sapiens)


name: L-serine(in) + Na(+)(in) = L-serine(out) + Na(+)(out)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Saccharomyces cerevisiae)


name: F1 binds to F2 forming the F subunit (Homo sapiens)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Canis familiaris)


name: Release Of ADP From Myosin (Canis familiaris)


name: an N-(1,2-saturated acyl)sphinganine + H(+) + NADPH + O2 <=> an N-(2-hydroxyacyl)-sphinganine + H2O + NADP(+)


name: 4-methyl-5-nitrocatechol + NAD(+) + nitrite => 2,4-dinitrotoluene + NADH + O2


name: Importin-8 binds AGO2:miRNA (Mus musculus)


name: scyllo-inositol dehydrogenase (NADP+) activity


name: 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2 <=> 3'-N-debenzoyltaxol + A + H2O


name: LDLR:LDL complex => LDLR + LDL (Rattus norvegicus)


name: RHOF auto-activates (Saccharomyces cerevisiae)


name: Interaction of NUMB with L1 (Mus musculus)


name: RHOA binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: 2xTRAP hydrolyzes FMN to RIB (Sus scrofa)


name: USP18 deubiquitinates TAK1:TAB1 (Bos taurus)


name: a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + ADP + H(+) => a 5'-end dephospho-2'-deoxyribonucleoside-DNA + ATP


name: FAR2 reduces PalmCoA to HXOL (Canis familiaris)


name: (4S)-limonene + H(+) + NADPH + O2 <=> H2O + limonene 1,2-epoxide + NADP(+)


name: ent-kaur-16-en-19-oate + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => gibberellin A12 aldehyde + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: (E,E)-piperlonguminine + CoA + H(+) => (E,E)-piperoyl-CoA + 2-methylpropan-1-amine


name: H2O2 + vanillin => 4-hydroxy-3-methoxy-benzenemethanol + O2


name: Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen (Bos taurus)


name: 2 N(omega)-hydroxy-L-arginine + 2 O2 + reduced [flavodoxin] <=> 3 H(+) + 2 H2O + 2 L-citrulline + 2 nitric oxide + oxidized [flavodoxin]


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Caenorhabditis elegans)


name: Arresten binds integrin alpha1beta1 (Canis familiaris)


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Drosophila melanogaster)


name: L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate


name: H2O + N-acetyl-beta-alanine = acetate + beta-alanine


name: ECE1 cleaves EDN1(53-90) (Canis familiaris)


name: 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin] => 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: Cleavage of thymine by TDG glycosylase (Drosophila melanogaster)


name: NAD(+) + pyridoxine => H(+) + NADH + pyridoxal


name: USP12, USP26 deubiquitinate AR (Drosophila melanogaster)


name: acetyl-CoA + pyruvate => (3S)-citramalyl-CoA


name: KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 (Sus scrofa)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Xenopus tropicalis)


name: D-ribulose 1,5-bisphosphate + H2O <=> D-ribulose 1-phosphate + phosphate


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Drosophila melanogaster)


name: [thioredoxin]-dithiol + cumene hydroperoxide <=> 2-phenylpropan-2-ol + [thioredoxin]-disulfide + H2O


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => H(+) + hexadecanoate + hexadecanoyl-glycero-3-phospho-(1D-myo-inositol)


name: K63polyUb-IRAK1 dissociates (Drosophila melanogaster)


name: diosgenin + UDP-alpha-D-glucose => diosgenin 3-O-beta-D-glucoside + H(+) + UDP


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Canis familiaris)


name: H2O + L-glutamate + NADP(+) => 2-oxoglutarate + H(+) + NADPH + NH4(+)


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Gallus gallus)


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Canis familiaris)


name: chlorophyll a + diphosphate => chlorophyllide a + H(+) + phytyl diphosphate


name: Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Drosophila melanogaster)


name: 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite => 2 H(+) + 3 H2O + hydrogen sulfide + 3 oxidized coenzyme F420-(gamma-L-Glu)(n)


name: ADP + H(+) + hexadecanedioate(out) + phosphate => ATP + H2O + hexadecanedioate(in)


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine


name: dGMP + NAD(+) => H(+) + N(2)-(ADP-D-ribosyl)-dGMP + nicotinamide


name: ATP + coproporphyrin III(in) + H2O = ADP + coproporphyrin III(out) + H(+) + phosphate


name: Fibrillin-1 degradation by MMP14 (Rattus norvegicus)


name: S-adenosyl 3-(methylsulfanyl)propylamine + spermine = H(+) + N(4)-aminopropylspermine + S-methyl-5'-thioadenosine


name: Proteolytic cleavage of complement factor C4 (Gallus gallus)


name: FADH2-C4alpha-hydroperoxide + NAD(+) => FAD + 2 H(+) + NADH + O2


name: (S)-reticuline + S-adenosyl-L-methionine <=> (S)-laudanine + H(+) + S-adenosyl-L-homocysteine


name: L-seryl-[protein] + phosphate => H2O + O-phospho-L-seryl-[protein]


name: EHMT1:EHMT2 methylates IL6 promoter (Drosophila melanogaster)


name: 2 (3,4-dimethoxyphenyl)methanol radical + 2 H2O => 2 (3,4-dimethoxyphenyl)methanol + H2O2


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Drosophila melanogaster)


name: sodium-transporting ATPase activity, rotational mechanism


name: 4 H(+) + luteothin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = aureothin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: L-isoleucine(out) + Na(+)(out) => L-isoleucine(in) + Na(+)(in)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Gallus gallus)


name: POU5F1 and SOX2 bind the ZIC1 gene (Homo sapiens)


name: (R)-lactate + ATP + D-alanine => ADP + D-alanyl-(R)-lactate + phosphate


name: (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O => (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Bos taurus)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Homo sapiens)


name: KRAS4B is phosphorylated on serine 181 (Caenorhabditis elegans)


name: N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine


name: choline + N-(hexanoyl)-sphing-4-enine-1,3-cyclic phosphate => N-hexanoyl-sphing-4-enine-1-phosphocholine


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Canis familiaris)


name: 1-O-alkyl-sn-glycero-3-phosphocholine + an acyl-CoA => 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA


name: IL7:IL7R:JAK1 binds IL2RG:JAK3 (Sus scrofa)


name: 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O => ADP-D-ribose + H(+) + L-glutamyl-[protein]


name: choline(in) + 2 H(+)(out) = choline(out) + 2 H(+)(in)


name: promoter-enhancer loop anchoring activity


name: SHC1 in the RET complex is phosphorylated (Sus scrofa)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Saccharomyces cerevisiae)


name: (S)-2-amino-6-oxohexanoate + H2O + NAD(+) <=> 2 H(+) + L-2-aminoadipate + NADH


name: DGO binds to PK (Drosophila melanogaster)


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + S-adenosyl-L-methionine => a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide + H(+) + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: L-Glutamine transport into neurons (Sus scrofa)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Drosophila melanogaster)


name: a (4R,8E)-4-hydroxysphingenine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Addition of galactose by beta 4-galactosyltransferases (Sus scrofa)


name: CD4 binds Interleukin-16 (Gallus gallus)


name: DHFR dimer binds DHFR inhibitors (Dictyostelium discoideum)


name: H(+) + NADH + NH4(+) + S-(acetaldehyde)-L-cysteine => H2O + NAD(+) + S-(2-aminoethyl)-L-cysteine


name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Danio rerio)


name: (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate => (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate


name: 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] => 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-glutamine(out) + L-threonine(in) + Na(+)(in) => L-glutamine(in) + L-threonine(out) + Na(+)(out)


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Homo sapiens)


name: 4-hydroxy-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA => 2 H(+) + 2 malonyl-CoA + octadecanoyl-CoA


name: Aquaporin-4 passively transports water out of cell (Plasmodium falciparum)


name: 15-cis-phytoene + a plastoquinone <=> 15,9'-di-cis-phytofluene + a plastoquinol


name: ATP + H2O + leukotriene C4(out) = ADP + H(+) + leukotriene C4(in) + phosphate


name: CAMK1 binds calmodulin (Canis familiaris)


name: CoA + decanoate + H(+) => decanoyl-CoA + H2O


name: GUSB tetramer hydrolyses (HA)2 (Mus musculus)


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Sus scrofa)


name: Reinsertion of L1 into the plasma membrane (Homo sapiens)


name: CyP60 chaperones Basigin (Gallus gallus)


name: CDK1 phosphorylates VCPIP1 (Homo sapiens)


name: Phosphorylation of CI by PKA-C1 (Drosophila melanogaster)


name: H2O + sucrose = alpha-D-glucose + beta-D-fructose


name: quercetin + UDP-alpha-D-glucose <=> H(+) + quercetin 3-O-beta-D-glucoside + UDP


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Caenorhabditis elegans)


name: acetyl phosphate + L-lysyl-[protein] => H(+) + N(6)-acetyl-L-lysyl-[protein] + phosphate


name: acetyl-CoA + H(+) + 3 malonyl-CoA + S-adenosyl-L-methionine <=> 3-methylorsellinate + 3 CO2 + 4 CoA + S-adenosyl-L-homocysteine


name: ULK complex translocates to the ER (Gallus gallus)


name: SEC31:SEC13 and v-SNARE recruitment (Canis familiaris)


name: n fibrin monomers -> fibrin multimer (Mus musculus)


name: PAK1-3 dimer disassociates (Caenorhabditis elegans)


name: alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose <=> [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + H(+) + UDP


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Homo sapiens)


name: Phosphorylation and activation of eIF4G by activated S6K1 (Sus scrofa)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Canis familiaris)


name: CO2 + deacetoxycephalosporin C + H2O + succinate => 2-oxoglutarate + O2 + penicillin N


name: SRD5A1 dehydrogenates TEST to DHTEST (Rattus norvegicus)


name: (11E,13Z)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (11E)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: anthranilate + benzoyl-CoA = CoA + N-benzoylanthranilate


name: diuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 3-(3,4-dichlorophenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Homo sapiens)


name: O-phosphoseryl-tRNA(Sec) selenium transferase activity


name: p-EPHB phosphorylates SDC2 (Rattus norvegicus)


name: ZFP36 (TTP) recruits RNA degradation activities (Sus scrofa)


name: HRSP12 deaminates 2AA to 2OBUTA (Schizosaccharomyces pombe)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Dictyostelium discoideum)


name: FGFR2c binds to FGF (Drosophila melanogaster)


name: DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)


name: H2O + validoxylamine A 7'-phosphate => phosphate + validoxylamine A


name: Phosphorylation of Chk1 by ATR (Gallus gallus)


name: ADP + ATP => adenosine 5'-tetraphosphate + AMP


name: A + AMP + diphosphate + ilicicolin B => AH2 + ATP + ilicicolinate B


name: CDC42 translocates to the endoplasmic reticulum membrane (Caenorhabditis elegans)


name: 1D-myo-inositol 1,4,5-trisphosphate + ATP <=> 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Drosophila melanogaster)


name: Mitochondrial BTD hydrolyses BCTN (Danio rerio)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Dictyostelium discoideum)


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Sus scrofa)


name: Dephosphorylation of Lck-pY505 by CD45 (Rattus norvegicus)


name: (3R)-hydroxy-(13Z)-docosenoyl-CoA + NADP(+) => (13Z)-3-oxodocosenoyl-CoA + H(+) + NADPH


name: COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates (Rattus norvegicus)


name: HLTF polyubiquitinates monoubiquitinated PCNA (Bos taurus)


name: RHAG transports CO2 from extracellular region to cytosol (Gallus gallus)


name: Defective HEXB does not cleave the terminal GalNAc from keratan sulfate (Homo sapiens)


name: (2S)-carthamidin-4',7-dimethyl ether + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin 4',7-dimethyl ether + O2 + reduced [NADPH--hemoprotein reductase]


name: (E)-4-hydroxynon-2-enal + H(+) + NADPH => 4-hydroxynonanal + NADP(+)


name: DSH binds to DAAM (Drosophila melanogaster)


name: Reorientation of glucosaminyl-acyl-PI in the endoplasmic reticulum membrane (Homo sapiens)


name: (R)-3-phenyllactoyl-CoA => (E)-cinnamoyl-CoA + H2O


name: glycerol + H(+) + octanoate => H2O + octanoylglycerol


name: odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Gallus gallus)


name: 4alpha-methylzymosterol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 = 4alpha-carboxyzymosterol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: peniphenone D => (R)-5-methyl-tetronate + o-quinone methide


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Canis familiaris)


name: PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: DELE1(143-515) is released into the cytosol (Rattus norvegicus)


name: Fibronectin degradation by MMP14 (Xenopus tropicalis)


name: a 2-iminocarboxylate + H2O2 => a D-alpha-amino acid + O2


name: 3'-phosphoadenylyl sulfate + chenodeoxycholate => adenosine 3',5'-bisphosphate + chenodeoxycholate 7-sulfate + H(+)


name: H(+) + N-[(R)-pantothenoyl]-L-cysteine => (R)-pantetheine + CO2


name: (5Z,8Z,11Z,14Z)-eicosatetraenedioate + 2 H(+) + NADH => 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O + NAD(+)


name: ITP + oxaloacetate <=> CO2 + IDP + phosphoenolpyruvate


name: 4-hydroxybenzoate + H(+) => CO2 + phenol


name: a 1,2-diacyl-sn-glycerol + CTP <=> a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H(+)


name: H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Mus musculus)


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Xenopus tropicalis)


name: PIAS2-2 SUMOylates THRA with SUMO1 (Homo sapiens)


name: ESTG binds ESR2:chaperone complex (Sus scrofa)


name: Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm (Rattus norvegicus)


name: (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase] <=> acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP + H2O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dUMP


name: ecdysone + O2 => 3-dehydroecdysone + H2O2


name: RHOD binds effectors at the mitochondrial outer membrane (Danio rerio)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Mus musculus)


name: p-4Y-SIRPA:CD47:SKAP2 binds FYB (Canis familiaris)


name: Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Xenopus tropicalis)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Homo sapiens)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Saccharomyces cerevisiae)


name: Caspase mediated cleavage of C-IAP1 (Homo sapiens)


name: Granzyme-B activates BID by cleavage (Canis familiaris)


name: H(+)(in) + melibiose(in) = H(+)(out) + melibiose(out)


name: 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity


name: PRC2 trimethylates histone H3 at lysine-27 (Bos taurus)


name: HEXA cleaves the terminal GalNAc from small HA fragments (Bos taurus)


name: DBT transfers BCAA to CoA (Xenopus tropicalis)


name: H(+) + kanamycin A + UDP => 2'-deamino-2'-hydroxyneamine + UDP-alpha-D-kanosamine


name: AMP + diphosphate + hexanoyl-CoA => ATP + CoA + hexanoate


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Bos taurus)


name: (2S)-2-aminobutanoate + 3-(4-hydroxyphenyl)pyruvate => 2-oxobutanoate + L-tyrosine


name: 2-oxoglutarate + H(+) + L-arginine + NADPH => D-nopaline + H2O + NADP(+)


name: Assembly of the anterograde IFT train (Homo sapiens)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 glutathione => (5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: 2-oxoglutarate + O2 + pentalenolactone D => CO2 + H2O + pentalenolactone E + succinate


name: acetyl-CoA + citramalate = (3S)-citramalyl-CoA + acetate


name: cytidine(62) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(62) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: The receptor:G-protein complex dissociates (Gallus gallus)


name: (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Bos taurus)


name: LKB1 forms a trimeric complex with STRAD and MO25 (Rattus norvegicus)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Canis familiaris)


name: a ganglioside GM1alpha + CMP + H(+) => a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate


name: Exocytosis of secretory granule lumen proteins (Canis familiaris)


name: MscR reduces nitrosomycothiol to ammonia (Homo sapiens)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Schizosaccharomyces pombe)


name: 2-oxoglutarate + dodecanoyl-CoA + H2O = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+)


name: 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Dictyostelium discoideum)


name: Connexin 45/Connexin 36 mediated neuronal gap junction communication (Mus musculus)


name: (2E,6E)-farnesyl diphosphate = bicyclogermacrene + diphosphate


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Danio rerio)


name: H2O + pyridoxine 5'-phosphate = phosphate + pyridoxine


name: RBKS phosphorylates ribose to R5P (Mus musculus)


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Gallus gallus)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Plasmodium falciparum)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 2-oxoglutarate + chrodrimanin E + O2 <=> chrodrimanin A + CO2 + succinate


name: 2-glyceryl-15-deoxy-Delta(12,14)-prostaglandin J2 + H2O => 15-deoxy-Delta(12,14)-prostaglandin J2 + glycerol + H(+)


name: a quinol + methane + O2 <=> a quinone + H2O + methanol


name: Interaction of other adapter proteins with p-KIT (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol + diphosphate


name: MET bound PI3K generates PIP3 (Sus scrofa)


name: fluoride + glycolate + H(+) => fluoroacetate + H2O


name: (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA <=> (2E,11Z,14Z)-eicosatrienoyl-CoA + H2O


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Rattus norvegicus)


name: Conversion of C4 into C4a and C4b (Canis familiaris)


name: BBSome binds RAB3IP (Caenorhabditis elegans)


name: CRLF1:IL27 translocates to the extracellular region (Sus scrofa)


name: Accumulation of M1 at the inner leaflet of the lipid bilayer (Homo sapiens)


name: PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane (Homo sapiens)


name: COX18 inserts nascent MT-CO2 in COX20:TMEM77 (Homo sapiens)


name: TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin (Homo sapiens)


name: H2O + omega-dicarboxyl-CoA => a dicarboxylate + CoA + H(+)


name: ATP + CoA + nicotinate <=> AMP + diphosphate + nicotinyl-CoA


name: Aquaporins passively transport glycerol out of cells (Schizosaccharomyces pombe)


name: [trehalose-6-phosphate synthase]-L-cysteine + S-adenosyl-L-methionine = [trehalose-6-phosphate synthase]-S-methyl-L-cysteine + H(+) + S-adenosyl-L-homocysteine


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)


name: a fatty acyl-CoA + sphinganine = an N-acylsphinganine + CoA + H(+)


name: The Kiss receptor GPR54 binds kisspeptin (Mus musculus)


name: SIRT4 cleaves lipoyl from DLAT (Homo sapiens)


name: AP2 binds chlorpromazine (Canis familiaris)


name: dimethyl sulfide + H(+) + NADH + O2 <=> dimethyl sulfoxide + H2O + NAD(+)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)


name: a (2R)-2-hydroperoxy fatty acid + H(+) => a fatty aldehyde + CO2 + H2O


name: phosphogluco-amylopectin water dikinase activity


name: FA core complex:HSP70s binds PKR (Rattus norvegicus)


name: G protein-coupled folate receptor activity


name: CysGly translocates from extracellular region to cytosol (Homo sapiens)


name: Constitutive phosphorylation by GSK3 (Homo sapiens)


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Homo sapiens)


name: 2-oxoglutarate + D-lysine => 6-amino-2-oxohexanoate + D-glutamate


name: GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)


name: ATM phosphorylates HERC2 (Drosophila melanogaster)


name: RBBP7 binds histone H3 (Schizosaccharomyces pombe)


name: 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol => 1alpha,2beta,25-trihydroxycholecalciferol + 3-hydroxypropanal


name: Transport of MHC II:Ii complex to plasma membrane (Homo sapiens)


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Sus scrofa)


name: PXLP-K754-GLDC dimer decarboxylates Gly (Schizosaccharomyces pombe)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: MMAA:MUT binds AdoCbl (Rattus norvegicus)


name: 3-hydroxypropanal + H2O + NADP(+) <=> 3-hydroxypropanoate + 2 H(+) + NADPH


name: benzylamine + H2O + NAD(+) = benzaldehyde + H(+) + NADH + NH4(+)


name: Autocatalytic phosphorylation of FGFR4 (Homo sapiens)


name: Ca2+ influx through voltage gated Ca2+ channels (Drosophila melanogaster)


name: TBC1D7 binds the TSC1-TSC2 complex (Drosophila melanogaster)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Saccharomyces cerevisiae)


name: NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: Addition of galactose by beta 4-galactosyltransferases (Drosophila melanogaster)


name: MRN complex bound to DNA ends recruits ATM (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine = 1-(10Z-heptadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH => 3-deoxyglucosone + H2O + NAD(+)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O => acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + H2O = 1-O-hexadecyl-sn-glycerol + acetate + H(+)


name: AMP + H(+) + nebramycin 5' => carbamoyl adenylate + tobramycin


name: Phosphorylation of PLCgamma by PDGFR (Rattus norvegicus)


name: Transcription of POU5F1 (OCT4) (Homo sapiens)


name: IL12B:IL12B translocates from ER lumen to the extracellular region (Bos taurus)


name: Lysosomal degradation of gap junction plaques (Homo sapiens)


name: indole-3-pyruvate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tryptophan


name: 3 H(+) + NADPH + O2 + 2 rubrofusarin B <=> 2 H2O + NADP(+) + nigerone


name: CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) (Homo sapiens)


name: "Catalysing the translocation of other compounds"


name: Phosphorylated AMPK binds AMP (Drosophila melanogaster)


name: 3-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => 3-methyl-(2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]


name: eicosan-1-ol + hexadecanoyl-CoA = CoA + eicosanyl hexadecanoate


name: H2O + o-orsellinate depside = H(+) + 2 orsellinate


name: a glycerophospholipid(in) + ATP + H2O = a glycerophospholipid(out) + ADP + H(+) + phosphate


name: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate


name: Integrin alphaIIb beta3 activation (Xenopus tropicalis)


name: DAG is acylated to TAG by DGAT1/2 (Plasmodium falciparum)


name: COQ4 decarboxylates MHDB (Canis familiaris)


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Drosophila melanogaster)


name: EDNRA binds selective ERAs (Rattus norvegicus)


name: cytidine(2499) in 23S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(2499) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Mus musculus)


name: (3beta)-hydroxy-cholest-5-en-26-oate + H2O + NADP(+) => (3beta)-hydroxy-cholest-5-en-26-al + NADPH + O2


name: Endonucleolytic RISC hydrolyzes target RNAs (Canis familiaris)


name: H2O + holo-[ACP] <=> (R)-4'-phosphopantetheine + apo-[ACP] + H(+)


name: cephalosporin C + CoA => acetyl-CoA + deacetylcephalosporin C


name: 4-hydroxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP => 4-hydroxyestrone + UDP-alpha-D-glucuronate


name: AH2 + O2 + phylloquinone = 2,3-epoxyphylloquinone + A + H2O


name: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: SUMOylation of NFKB2 with SUMO1 (Mus musculus)


name: ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Bos taurus)


name: an 11beta-hydroxysteroid + NAD(+) = an 11-oxosteroid + H(+) + NADH


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + polyneuridine aldehyde


name: RND2 binds effectors (Schizosaccharomyces pombe)


name: fenuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 1-methyl-3-phenylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2 H(+) + H2O + N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase] => L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase]


name: (9S)-hydroperoxy-(10E,12Z)-octadecadienoate = colneleate + H2O


name: PTK2beta binds alphaVbeta3 (Caenorhabditis elegans)


name: D-histidine(out) + H(+)(out) + L-ornithine(in) => D-histidine(in) + H(+)(in) + L-ornithine(out)


name: PTK2 autophosphorylates (Canis familiaris)


name: ITCH gene expression is stimulated by RUNX1 and YAP1 (Homo sapiens)


name: Connexin 62 mediated neuronal gap junction communication (Mus musculus)


name: rifamycin SV ortho-naphthoquinone carboxamide = rifamycin SV para-naphthoquinone carboxamide


name: Initiation of SAHF formation (Canis familiaris)


name: Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Xenopus tropicalis)


name: H(+) + methane + NADH + O2 <=> H2O + methanol + NAD(+)


name: a 2-oxocarboxylate + H2O2 => a (2S)-2-hydroxycarboxylate + O2


name: C30 botryococcene + 2 S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: NFE2L2-dependent ME1 gene expression (Homo sapiens)


name: ATP + H2O + L-alanylglycine(out) = ADP + H(+) + L-alanylglycine(in) + phosphate


name: ATP + L-arginine + L-tyrosine <=> AMP + diphosphate + H(+) + L-tyrosyl-L-arginine


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Homo sapiens)


name: 11-oxomiltiradiene + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: SMURF1/2 dissociates from ub-PTCH1 (Bos taurus)


name: COPI vesicle uncoating at the ER (Danio rerio)


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Homo sapiens)


name: HTRA2 degrades APP (Amyloid-beta precursor protein) (Sus scrofa)


name: monoatomic cation efflux transmembrane transporter activity


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Rattus norvegicus)


name: AGK:Mg2+ phosphorylates MAG, DAG (Homo sapiens)


name: Furin cleaves pro-factor IX to factor IX (Xenopus tropicalis)


name: RHOD translocates to the Golgi membrane (Xenopus tropicalis)


name: LIPC dimer hydrolyses TAG to DAG and FA (Rattus norvegicus)


name: SUMOyation of DNMT1 with SUMO1 (Rattus norvegicus)


name: Expression of APOD regulated by NR1H2 or NR1H3 (Homo sapiens)


name: Phosphorylation of INFAR1 by TYK2 (Gallus gallus)


name: guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine


name: ENPP6 hydrolyzes lysophosphatidylcholine (Rattus norvegicus)


name: dec-9-ynoyl-[ACP] + 4 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] => decanoyl-[ACP] + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: (2R,3R)-dihydrokaempferol + CO2 + succinate => (2S)-naringenin + 2-oxoglutarate + O2


name: a 2'-deoxyadenosine in DNA + acetyl-CoA + AH2 + NH4(+) + O2 <=> A + a N(6)-methylcarbamoyl-2'-deoxyadenosine in DNA + CoA + H(+) + 2 H2O


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 = 2-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-glycerol


name: Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Xenopus tropicalis)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Rattus norvegicus)


name: ATP + L-aspartate + tRNA(Asp) <=> AMP + diphosphate + L-aspartyl-tRNA(Asp)


name: 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + trans,octa-cis-decaprenyl phosphate <=> diphosphate + trans,octa-cis-decaprenylphospho-beta-D-ribofuranose 5-phosphate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Danio rerio)


name: Cis-Heterodimerization of nephrin and KIRREL (Bos taurus)


name: Binding of ERp57 (Dictyostelium discoideum)


name: lithocholate + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxylithocholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of the WRAD complex (Homo sapiens)


name: Alpha1-Microglobulin binds heme (Sus scrofa)


name: agmatine + urea => 1,4-diguanidinobutane + H2O


name: Addition of galactose by beta 4-galactosyltransferases (Danio rerio)


name: H2O + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Gallus gallus)


name: Lactoperoxidase (LPO) produces OSCN- (Dictyostelium discoideum)


name: Small molecule inhibitor binds RIPK1, RIPK3 (Homo sapiens)


name: SLC25A10 mediates exchange of malate and phosphate (Saccharomyces cerevisiae)


name: (3S)-citryl-CoA <=> acetyl-CoA + oxaloacetate


name: (5S)-hydroxy-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase] => 5-oxo-(6E,8Z)-octadecadienoate + H(+) + 2 H2O + oxidized [NADH--hemoprotein reductase]


name: beta-D-fructose 1,6-bisphosphate + H2O => beta-D-fructose 6-phosphate + phosphate


name: KIR2DS2 interacting with HLA-C group 1 (Cw3) (Mus musculus)


name: Uncoupled eNOS favours the formation of superoxide (Plasmodium falciparum)


name: snRNA Cap hypermethylation (Homo sapiens)


name: Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Mus musculus)


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Drosophila melanogaster)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: a neolactoside nLc4Cer + H(+) + UDP => beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + UDP-alpha-D-galactose


name: Phosphorylation of cohesin by PLK1 at centromeres (Homo sapiens)


name: UGCG transfers glucose to ceramide (Drosophila melanogaster)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 2,3-di-(9Z)-octadecenoyl-sn-glycerol


name: (1Z,2S)-2-methylbutanal oxime => (2S)-2-methylbutanenitrile + H2O


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-alanine + O2 = (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2


name: (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one <=> (3S)-3-isopropenyl-6-oxoheptanoate + H(+)


name: (+)-amorpha-4,11-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> (+)-artemisinic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MTMR12 binds MTM1 (Caenorhabditis elegans)


name: Activated FGFR3 binds FRS3 (Homo sapiens)


name: VMAT1/2 can mediate the transport of biogenic amines (Sus scrofa)


name: Deacetylation of cohesin (Gallus gallus)


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Mus musculus)


name: 3,4,5-trihydroxybenzoate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + 2 H(+)


name: 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-galactose => 3-O-(beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-L-Fuc)-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: formate efflux transmembrane transporter activity


name: Release of the SLBP independent Histone mRNA from the NPC (Drosophila melanogaster)


name: (4R)-limonene + H(+) + NADPH + O2 = H2O + limonene 1,2-epoxide + NADP(+)


name: D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate


name: GMP(out) + NAD(+)(in) => GMP(in) + NAD(+)(out)


name: D-glucaro-1,4-lactone <=> 5-dehydro-4-deoxy-D-glucarate + H(+)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Rattus norvegicus)


name: 4-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate = 4-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine <=> 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 4 H(+) + 3 L-methionine


name: (9Z,12Z)-octadecadienoate + glycerol + H(+) => 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)


name: HAO2 tetramer oxidises 2OH-PALM (Caenorhabditis elegans)


name: Phosphorylation of GAB2 by SFKs (Homo sapiens)


name: PapA5 transforms mycocerosyl to PDIM (Mycobacterium tuberculosis)


name: abacavir [extracellular] => abacavir [cytosol] (Rattus norvegicus)


name: ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate


name: (6S)-NADHX + ATP => ADP + H(+) + NADH + phosphate


name: myo-inositol + S-adenosyl-L-methionine => 1D-3-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Rattus norvegicus)


name: CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)


name: Dephosphorylation of CK2-modified condensin I (Drosophila melanogaster)


name: RAC2 binds effectors at the plasma membrane (Gallus gallus)


name: 6-deoxo-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 6alpha-hydroxy-28-nortyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CoA + H(+) + N-hexacosenoylsphinganine => hexacosenoyl-CoA + sphinganine


name: TRADD:TRAF2:RIP1 complex binds FADD (Mus musculus)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Bos taurus)


name: 1,3,7-trimethylurate + a ubiquinol => a ubiquinone + caffeine + H2O


name: glycerol + H(+) + sn-glycerol 3-phosphate => H2O + sn-glycero-3-phospho-(1'-rac-glycerol)


name: H2O + N(2)-(4-aminobutanoyl)-L-ornithine <=> 4-aminobutanoate + L-ornithine


name: PTPRZ dephosphorylates ligand-bound ALK dimers (Rattus norvegicus)


name: ATP + H2O + iron(III) dicitrate(out) => ADP + H(+) + iron(III) dicitrate(in) + phosphate


name: p-S54,92,203-BRF1 binds 14-3-3 (Caenorhabditis elegans)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Drosophila melanogaster)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Rattus norvegicus)


name: 5-phospho-alpha-D-ribose 1-diphosphate + neamine = 5''-phosphoribostamycin + diphosphate


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Canis familiaris)


name: H2O + N-methyl-L-alanine + NADP(+) <=> H(+) + methylamine + NADPH + pyruvate


name: prostaglandin E2(out) = prostaglandin E2(in)


name: 7-chloroindole-3-pyruvate imine dimer => dichlorochromopyrrolate + H(+) + NH4(+)


name: cholate + deoxycholoyl-CoA = choloyl-CoA + deoxycholate


name: a sphingosylphosphocholine + H2O => a sphingoid base + H(+) + phosphocholine


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Caenorhabditis elegans)


name: ACLY tetramer transforms CIT to Ac-CoA (Caenorhabditis elegans)


name: inosine(in) + 2 Na(+)(in) => inosine(out) + 2 Na(+)(out)


name: (E)-coniferaldehyde + UDP-alpha-D-glucose => 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + H(+) + UDP


name: H2O + O2 + putrescine = 4-aminobutanal + H2O2 + NH4(+)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: Fibronectin degradation by MMP14 (Caenorhabditis elegans)


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Danio rerio)


name: jasmonate + S-adenosyl-L-methionine = methyl (-)-jasmonate + S-adenosyl-L-homocysteine


name: 2 H(+) + O2 + 2 sulochrin <=> 2 (2S)-bisdechlorogeodin + 2 H2O


name: H(+) + NADPH + O2 + phenol <=> catechol + H2O + NADP(+)


name: 3'-phosphoadenylyl sulfate + 3beta-hydroxy-5-cholenate <=> 3beta-sulfo-5-cholenate + adenosine 3',5'-bisphosphate + H(+)


name: p-T774-PKN1 binds CDC25C (Caenorhabditis elegans)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Mus musculus)


name: L-histidyl-[protein] + lactose 6-phosphate(in) => lactose(out) + N(pros)-phospho-L-histidyl-[protein]


name: GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Rattus norvegicus)


name: S-adenosyl-L-methionine + small RNA 3'-end nucleotide <=> H(+) + S-adenosyl-L-homocysteine + small RNA 3'-end 2'-O-methylnucleotide


name: PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser (Dictyostelium discoideum)


name: BESTs transport cytosolic HCO3- to extracellular region (Canis familiaris)


name: 2-oxoglutaramate + H2O <=> 2-oxoglutarate + NH4(+)


name: RNA polymerase II CTD heptapeptide repeat kinase activity


name: Direct recruitment of PI3K to p-KIT (Canis familiaris)


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Canis familiaris)


name: 26-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 26-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: acetyl-CoA + 7 H(+) + 5 malonyl-CoA + 3 NADPH => 5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 4 H2O + 3 NADP(+)


name: IL26:IL20RA:JAK1 binds IL10RB:TYK2 (Canis familiaris)


name: biotinate sulfoxide + H(+) + NADPH <=> biotin + H2O + NADP(+)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GA2 (d18:1(4E)) + H(+) + UDP


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Gallus gallus)


name: 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n) => H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline


name: CO2 + NADH + propanoyl-CoA => (S)-2-methyl-3-oxopropanoate + CoA + NAD(+)


name: (E)-caffeoyl-CoA + 5-hydroxyanthranilate => avenanthramide C + CoA


name: H2O + N(2)-benzoyl-D-arginine-4-nitroanilide = 4-nitroaniline + H(+) + N(2)-benzoyl-D-arginine


name: EOMES and TBXT bind the POU5F1 (OCT4) gene (Homo sapiens)


name: a hydroperoxide + L-cysteinyl-[protein] <=> an alcohol + S-hydroxy-L-cysteinyl-[protein]


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: AMP + diphosphate + octadecanoyl-[(hydroxy)phthioceranic acid synthase] => ATP + holo-[(hydroxy)phthioceranic acid synthase] + octadecanoate


name: APSe is phosphorylated to PAPSe by PAPSS1,2 (Homo sapiens)


name: CMP(out) + CMP-N-acetyl-beta-neuraminate(in) <=> CMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: Class IV antihypertensives bind LTCC multimer (Xenopus tropicalis)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Mus musculus)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Xenopus tropicalis)


name: Translocation of activated BAX to the mitochondria (Canis familiaris)


name: eNoSC dimethylates histone H3 at lysine-9 (Dictyostelium discoideum)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Caenorhabditis elegans)


name: (S)-2-hydroxyglutarate(in) + 3 Na(+)(in) => (S)-2-hydroxyglutarate(out) + 3 Na(+)(out)


name: Translocation of DFF to the nucleus (Gallus gallus)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Sus scrofa)


name: Cysteine is degraded to serine and H2S (Mus musculus)


name: Activation of TWIK-related K+ channel (TREK) (Rattus norvegicus)


name: 8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity


name: ATM phosphorylates EYA1-4 (Drosophila melanogaster)


name: N-WASP binds ARP2/3 and G-actin (Mus musculus)


name: 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+) => 1,2-dioctanoyl-sn-glycerol + CDP-choline


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Rattus norvegicus)


name: Pellino ubiquitinates IRAK1 (Dictyostelium discoideum)


name: CREB3L3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Bos taurus)


name: FRAT proteins bind GSK3beta (Homo sapiens)


name: Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)


name: NEIL1 cleaves thymine glycol from damaged DNA (Bos taurus)


name: Re-integration of insulin receptor into plasma membrane (Drosophila melanogaster)


name: a 2-acyl-sn-glycero-3-phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine


name: H2O + isomaltose = beta-D-glucose + D-glucose


name: PGLYRP3,4 binds bacterial peptidoglycan (Xenopus tropicalis)


name: BCKDK phosphorylates BCKDH (Mus musculus)


name: L-glucitol + NAD(+) => H(+) + keto-L-fructose + NADH


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Danio rerio)


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Sus scrofa)


name: ATP + H2O + L-methionine <=> diphosphate + phosphate + S-adenosyl-L-methionine


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Bos taurus)


name: COS binds to SMO (Drosophila melanogaster)


name: ProSPZ:SPZ dimer binds to TL receptor at the plasma membrane (Drosophila melanogaster)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate


name: KRAS4B recycles to the plasma membrane (Rattus norvegicus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 6 isopentenyl diphosphate => 6 diphosphate + tetra-trans,hexa-cis-undecaprenyl diphosphate


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) => 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP


name: Activation of STAT5a/b by JAK2 (Bos taurus)


name: 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein]


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Homo sapiens)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Canis familiaris)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Homo sapiens)


name: L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: PTK6 phosphorylates STAT3 (Homo sapiens)


name: ALOX5 oxidises DHA to 7-HDHA (Sus scrofa)


name: Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP (Mus musculus)


name: MECP2 binds MOBP gene promoter (Homo sapiens)


name: PP2A dephosphorylates inactive RAFs (Rattus norvegicus)


name: Syndecans 1, 2 & 4 bind VTN (Mus musculus)


name: CERT1-2 complex dissociates (Homo sapiens)


name: NFE2L2 binds CREBBP,EP300 (Rattus norvegicus)


name: high-affinity ferrous iron transmembrane transporter activity


name: (2E,11Z)-octadecadienoyl-CoA + H2O => (R)-3-hydroxy-(11Z)-octadecenoyl-CoA


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + (S)-mandelate + O2 <=> (6R)-L-erythro-6,7-dihydrobiopterin + (S)-4-hydroxymandelate + H2O


name: H2O + NAD(+) + nitrous oxide <=> H(+) + NADH + 2 nitric oxide


name: (2E)-geranyl diphosphate => (1S,4R)-camphene + diphosphate


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Mus musculus)


name: ATP + CoA + hexadecanedioate = AMP + diphosphate + hexadecanedioyl-CoA


name: Elastin degradation by MMP14 (Bos taurus)


name: RAC2 binds effectors at the plasma membrane (Rattus norvegicus)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Homo sapiens)


name: (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O => (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate


name: (2E)-geranyl diphosphate <=> (1S,5S)-beta-pinene + diphosphate


name: SUMOylation of XPC with SUMO1 (Gallus gallus)


name: O2 + phylloquinone + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein reductase]


name: NFE2L2 translocates from cytosol to nucleoplasm (Bos taurus)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: GDP-beta-L-fucose + L-seryl-[protein] <=> 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + GDP + H(+)


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 = 7-epi-cylindrospermopsin + CO2 + succinate


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Saccharomyces cerevisiae)


name: 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: ATP + N(4)-acetylcytidine = ADP + H(+) + N(4)-acetylcytidine 5'-phosphate


name: Reduction of presqualene diphosphate to form squalene (Rattus norvegicus)


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside => an anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-[(6-O-(E)-4-coumaroyl)glucoside] + CoA


name: estrone + PAPS => estrone 3-sulfate + PAP (Homo sapiens)