name: alpha-D-mannosyl-(1->4)-[3-O-methyl-alpha-D-mannosyl-(1->4)](n)-1-O,3-O-dimethyl-alpha-D-mannose + GDP + H(+) => [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-1-O,3-O-dimethyl-alpha-D-mannose + GDP-alpha-D-mannose


name: Cyclisation of GTP to precursor Z (Canis familiaris)


name: Endophilins recruit synaptojanins to the clathrin-coated pit (Sus scrofa)


name: a 5-methyluridine in 12S rRNA + H(+) + S-adenosyl-L-homocysteine => a uridine in 12S rRNA + S-adenosyl-L-methionine


name: COX15 transforms heme O to heme A (Sus scrofa)


name: ethyl 3-oxohexanoate + H(+) + NADPH => ethyl (R)-3-hydroxyhexanoate + NADP(+)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Sus scrofa)


name: DBT transfers BCAA to CoA (Mus musculus)


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Canis familiaris)


name: L-histidinol + NAD(+) <=> H(+) + L-histidinal + NADH


name: (2E)-hexadecenoyl-CoA + H2O => (3S)-hydroxyhexadecanoyl-CoA


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Bos taurus)


name: (5R)-hydroxy-beta-trans-bergamotene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-exo-beta-bergamotene + O2 + reduced [NADPH--hemoprotein reductase]


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Gallus gallus)


name: PC carboxylates PYR to OA (Saccharomyces cerevisiae)


name: PGH2 is isomerised to PGE2 by PTGES (Sus scrofa)


name: 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H2O <=> H(+) + hexadecanoate + sn-glycero-3-phospho-L-serine


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: H(+) + o-quinone methide + peniphenone D = penilactone A


name: GPR37L binds prosaposin (Canis familiaris)


name: CR2 binds C3d, C3dg, iC3b (Gallus gallus)


name: (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] = 13-hydroxy-alpha-tocopherol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RHOA binds effectors at the ER membrane (Mus musculus)


name: H2O + N-phosphocreatine => creatine + phosphate


name: NTPDase1 hydrolyzes nucleoside triphosphates (Homo sapiens)


name: Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Sus scrofa)


name: a (2R,3S,4S)-leucoanthocyanidin + NADP(+) => a (2R,3R)-dihydroflavonol + H(+) + NADPH


name: Thrombin proteolyzes IGF:IGFBP3:ALS (Homo sapiens)


name: ARMS is phosphorylated by active TrkA receptor (Canis familiaris)


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + AH2 => (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + A + H2O


name: 2-acetyl-3,4a,8,10,11,12a-hexahydroxy-1,4,4a,5,12,12a-hexahydrotetracene-1,12-dione + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + TAN-1612


name: MAOA:FAD deaminates DA to DOPAC (Sus scrofa)


name: Multiphospho-CERT1-2 binds PPM1L, VAPA/B (Danio rerio)


name: Ca impermeable AMPA receptor ligand binding (Mus musculus)


name: Addition of nucleotides leads to transcript elongation (Canis familiaris)


name: histamine + L-glutaminyl-[protein] => 5-histaminyl-L-glutamyl-[protein] + NH4(+)


name: ethyl acetate + H2O = acetate + ethanol + H(+)


name: 1,25(OH)2D binds VDR (Caenorhabditis elegans)


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)


name: MYC/MYCN bind the ALK gene (Homo sapiens)


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-seryl-[protein] + UDP


name: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 2-hydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HSF1 trimer translocates to the nucleus (Drosophila melanogaster)


name: RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)


name: STAMBPL1 is a deubiquitinase (Canis familiaris)


name: VTN binds collagens II, III and V (Bos taurus)


name: DOCK3 binds FYN associated with NTRK2 (Homo sapiens)


name: Activated FGFR2 phosphorylates PPTN11 (Gallus gallus)


name: 5-hydroxy-alpha-gurjunene + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine => an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine


name: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Drosophila melanogaster)


name: PVR:PVRL3 trans heterodimer interaction (Danio rerio)


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Drosophila melanogaster)


name: (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O = (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: H2O + S-(hercyn-2-yl)-L-cysteine S-oxide = 2-sulfenohercynine + NH4(+) + pyruvate


name: Expression of MEF2C in cardiogenesis (Homo sapiens)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Caenorhabditis elegans)


name: KALRN exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)


name: cytidine(in) + 2 Na(+)(in) => cytidine(out) + 2 Na(+)(out)


name: Activation of BAD by calcineurin (Sus scrofa)


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Xenopus tropicalis)


name: ARV1 transports CHOL from ER membrane to plasma membrane (Rattus norvegicus)


name: a globoside Gb3Cer (d18:1(4E)) + H2O => a fatty acid + a lysoGb3(d18:1(4E))


name: Dissociation of the Gi alpha:G olf complex (Bos taurus)


name: 2 H2O2 => O2 + 2 H2O (Rattus norvegicus)


name: 1-docosanoylglycerol + H2O => docosanoate + glycerol + H(+)


name: Removal of remaining Flap (Canis familiaris)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Sus scrofa)


name: Activated TP receptor binds G-proten Gq (Drosophila melanogaster)


name: ADP + arsenate(out) + H(+) + phosphate => arsenate(in) + ATP + H2O


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1HS,L1PA2,3 heterochromatin (Homo sapiens)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Rattus norvegicus)


name: a reduced flavin + NAD(+) => an oxidized flavin + 2 H(+) + NADH


name: MIB2 ubiquitinates CFLAR  (Homo sapiens)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2 H(+) + NADH + octadecanoate => H2O + NAD(+) + octadecanal


name: FDPS dimer transfers IPPP to GPP (Dictyostelium discoideum)


name: iE-DAP elicits a NOD1 response (Xenopus tropicalis)


name: atromentin + 2 H2O => 2 3-(4-hydroxyphenyl)pyruvate + H(+)


name: FGFR4 kinase mutants are inhibited by PD170734 (Homo sapiens)


name: cytidine(50) in tRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(50) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: DHAP is converted to G3P by GPD1/GPD1L (Schizosaccharomyces pombe)


name: 15,9'-di-cis-phytofluene + a plastoquinone => 9,9',15-tri-cis-zeta-carotene + a plastoquinol


name: Phosphorylation of TEC kinases by p-SYK (Bos taurus)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Canis familiaris)


name: BMG, BDG translocates from ER lumen to cytosol (Homo sapiens)


name: Latent TGF-beta-3 binds integrins (Caenorhabditis elegans)


name: HSP70 binds to HSP40:nascent protein (Canis familiaris)


name: Association of  NA into rafts (Homo sapiens)


name: TFAP2C homodimer binds the CDKN1A (p21) gene promoter (Homo sapiens)


name: DHF is reduced to tetrahydrofolate (THF) (Schizosaccharomyces pombe)


name: miR-17 microRNA binds CNOT6L mRNA (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 => (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate


name: L-alanine(in) + L-valine(out) = L-alanine(out) + L-valine(in)


name: hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 (Canis familiaris)


name: H2O + nigerose <=> alpha-D-glucose + D-glucose


name: Expression of BolA-like protein 2 (Homo sapiens)


name: H(+) + taxiphyllin + UDP => 4-hydroxymandelonitrile + UDP-alpha-D-glucose


name: sporulenol = (R)-tetraprenyl-beta-curcumene + H2O


name: PLK1 phosphorylates GORASP1 (Bos taurus)


name: L-fuculose 1-phosphate => (S)-lactaldehyde + dihydroxyacetone phosphate


name: 3'-phosphoadenylyl sulfate + alpha,alpha-trehalose <=> 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+)


name: UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Bos taurus)


name: T2Rs bind bitter-tasting compounds (Bos taurus)


name: JAK2 phosphorylation of GHR (Danio rerio)


name: ATP + CoA + nonanoate => AMP + diphosphate + nonanoyl-CoA


name: CYP7B1 7-hydroxylates 25OH-CHOL (Mus musculus)


name: 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => 1-O-alkyl-2,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: The bound receptor dimerizes (Gallus gallus)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Homo sapiens)


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)


name: 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine => 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: 4-methoxybenzoate + AH2 + O2 = 4-hydroxybenzoate + A + formaldehyde + H2O


name: PGH2 is isomerised to PGE2 by PTGES (Drosophila melanogaster)


name: MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin (Sus scrofa)


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) (Canis familiaris)


name: neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration


name: KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Drosophila melanogaster)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> (E)-2-epi-beta-caryophyllene + diphosphate


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Canis familiaris)


name: cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Mus musculus)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Rattus norvegicus)


name: Formation of MSH2:MSH6 Complex (Canis familiaris)


name: acetyl-CoA + L-homoserine => CoA + O-acetyl-L-homoserine


name: hexan-3-one + NADP(+) => (E)-4-hexen-3-one + H(+) + NADPH


name: LONP1 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Sus scrofa)


name: DCP1-DCP2 complex decaps mRNA (Canis familiaris)


name: SULTs transfer (SO4)2- group to PREG (Bos taurus)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] => 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Photolytic cleavage and thermal isomerization of 7-dehydroCHOL (Homo sapiens)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H(+) + UDP


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Sus scrofa)


name: Association of Emi1 with Cdc20 (Mus musculus)


name: Methylation of N-acetyl-5-HT to form melatonin (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+) => a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O


name: ATP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine <=> ADP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H(+) + phosphate


name: (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Caenorhabditis elegans)


name: CYTH proteins stimulate ARF1 GTPase activity (Sus scrofa)


name: geraniol kinase activity (ATP-dependent) activity


name: Recruitment of POLB to oxidatively damaged AP site (Danio rerio)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Danio rerio)


name: Connexin oligomerization in Trans-Golgi Network (TGN) (Homo sapiens)


name: Proteasomal clevage of exogenous antigen (Drosophila melanogaster)


name: stachyose galactinol:verbascose galactosyltransferase activity


name: Na(+)(out) + propanoate(out) <=> Na(+)(in) + propanoate(in)


name: (E)-non-2-enal + H2O + NADP(+) => (E)-non-2-enoate + 2 H(+) + NADPH


name: aminoacetone + CO2 + NADPH => L-allo-threonine + NADP(+)


name: NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP (Danio rerio)


name: H2O + Met-enkephalin-Arg-Phe = L-arginyl-L-phenylalanine + Met-enkephalin


name: H2O + L-seryl-tRNA(Ser) = L-serine + tRNA(Ser)


name: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 <=> CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: factor XII -> factor XIIa (Xenopus tropicalis)


name: Activation of conventional Protein Kinase C (Danio rerio)


name: (+)-epicubenol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Sus scrofa)


name: Phosphorylated PER rebinds to phosphorylated TIM (Drosophila melanogaster)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Homo sapiens)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Gallus gallus)


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Canis familiaris)


name: Binding of STAT1 to p-IFNGR1 (Mus musculus)


name: GRB2:SOS interacts with p-KIT (Rattus norvegicus)


name: Phosphorylation of cPLA2 by ERK-2 (Canis familiaris)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene <=> 1,2,4-trichlorobenzene + chloride + H(+)


name: H(+) + NADPH + O2 + 2 rubrofusarin B = aurasperone A + 2 H2O + NADP(+)


name: p-AMPK:AMP binds the ULK complex (Dictyostelium discoideum)


name: biotinyl-5'-AMP + L-lysyl-[protein] = AMP + 2 H(+) + N(6)-biotinyl-L-lysyl-[protein]


name: a uridine in mRNA + NH4(+) => a cytidine in mRNA + H(+) + H2O


name: Initial activation of proMMP2 by MMP14 (Mus musculus)


name: Ubiquitinated DVL is degraded by the proteasome (Bos taurus)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Dictyostelium discoideum)


name: hexanoate + methylamine => H2O + N-methylhexanamide


name: Necl-2:Nectin 3 trans heterodimer interaction (Rattus norvegicus)


name: 11-hydroxyferruginol + O2 + reduced [NADPH--hemoprotein reductase] => 11,20-dihydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FNTB inhibitors bind FNTA:FNTB (Danio rerio)


name: TP53 and AP-1 stimulate MSH2 expression (Homo sapiens)


name: H(+) + ipsdienone + NADH => (4R)-ipsdienol + NAD(+)


name: ATP + dodecanoate + holo-[ACP] => AMP + diphosphate + dodecanoyl-[ACP]


name: H(+) + NADPH + testosterone => 17beta-hydroxy-5alpha-androstan-3-one + NADP(+)


name: a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base + CoA + H(+)


name: CHSY1 transfers GalNAc to chondroitin (Drosophila melanogaster)


name: USP20, USP33 deubiquitinate ADRB2 (Drosophila melanogaster)


name: 1,7-dimethylxanthine + H(+) + NADH + O2 = 7-methylxanthine + formaldehyde + H2O + NAD(+)


name: (E)-caffeoyl-CoA + S-adenosyl-L-methionine <=> (E)-feruloyl-CoA + H(+) + S-adenosyl-L-homocysteine


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Plasmodium falciparum)


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Danio rerio)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Plasmodium falciparum)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Drosophila melanogaster)


name: a sphingoid base + H(+) + phosphocholine => a sphingosylphosphocholine + H2O


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Mus musculus)


name: glyoxylate + N(omega)-methyl-L-arginine = 5-(3-methylguanidino)-2-oxopentanoate + glycine


name: Translocation of WWTR1 (TAZ) to the nucleus (Gallus gallus)


name: a sphingomyelin(in) => a sphingomyelin(out)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Schizosaccharomyces pombe)


name: Phosphorylation of YAP by LATS1 (Xenopus tropicalis)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Sus scrofa)


name: a diacylglycerol + an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine => a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine


name: PIAS4 SUMOylates PPARA with SUMO1 (Homo sapiens)


name: 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + CO2 + S-adenosyl-L-methionine = 2 H(+) + S-adenosyl-L-homocysteine + wybutosine(37) in tRNA(Phe)


name: ATP + H2O + N-[(S)-lactoyl]-L-phenylalanine(in) => ADP + H(+) + N-[(S)-lactoyl]-L-phenylalanine(out) + phosphate


name: Formation of collagen fibrils (Bos taurus)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+) => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O


name: PTPN11 dephosphorylates RUNX1 (Bos taurus)


name: AH2 + menaquinone-9 => A + beta-dihydromenaquinone-9


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Dictyostelium discoideum)


name: GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Rattus norvegicus)


name: Melanin-concentrating hormone receptors bind MCH (Gallus gallus)


name: RAC1 and CDC42 activate PAK2 (Drosophila melanogaster)


name: Caspase-mediated cleavage of Desmoglein 1 (Bos taurus)


name: ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Drosophila melanogaster)


name: KDM5A-D demethylate Me3K5-histone H3 (Rattus norvegicus)


name: G alpha (q) binds to Trio family RhoGEFs (Canis familiaris)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Sus scrofa)


name: eicosanoate + glycine => H2O + N-eicosanoylglycinate


name: NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP (Danio rerio)


name: (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein] => 2-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Mus musculus)


name: an acyl-CoA + sn-glycero-3-phosphoethanolamine = a 2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + UDP-alpha-D-glucose => (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H(+) + UDP


name: Tyrosine is monoiodinated (Mus musculus)


name: 2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH


name: adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: a fatty acyl-CoA + a long chain fatty alcohol = a wax ester + CoA


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Bos taurus)


name: D-sorbopyranose + H2O2 => D-sorbitol + O2


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: 1,4-menthane-3,8-diol + H2O + NADP(+) => (-)-menthol + H(+) + NADPH + O2


name: NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: Receptor FFAR1 binds free fatty acids (Homo sapiens)


name: Interaction of DAP12 and IREM2 (Mus musculus)


name: Formation of hydroxylysyl-pyrrole cross-links (Sus scrofa)


name: BTG2 binds CCR4-NOT complex (Xenopus tropicalis)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Mus musculus)


name: 3-hydroxybenzoate + H(+) + NADPH + O2 <=> 3,4-dihydroxybenzoate + H2O + NADP(+)


name: 2 H(+) + sulfite + thiocyanate => hydrogen cyanide + thiosulfate


name: 5-oxo-L-proline + L-lysine => epsilon-(gamma-L-glutamyl)-L-lysine


name: ME1 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)


name: L1 binds to AP-2 Clathrin complex (Mus musculus)


name: beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => all-trans-zeaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: RNF8 and RNF168 ubiquitinate KDM4A,B (Drosophila melanogaster)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Xenopus tropicalis)


name: anthranilate + 3 H(+) + NADPH + O2 <=> catechol + CO2 + NADP(+) + NH4(+)


name: 5-methyl-1-naphthoate + H(+) + NADPH + O2 => 3-hydroxy-5-methyl-1-naphthoate + H2O + NADP(+)


name: viral dsRNA binds IFIH1:TKFC (Homo sapiens)


name: an anthocyanidin 3-O-sophoroside + 2 H(+) + UDP => an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose


name: ADP + H(+) + phosphate + taurochenodeoxycholate 3-sulfate(out) => ATP + H2O + taurochenodeoxycholate 3-sulfate(in)


name: Receptor CCR9  binds CCL25 ligand (Gallus gallus)


name: 12-octadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + H(+) + octadecanoate


name: Joining of adjacent Okazaki fragments (Rattus norvegicus)


name: HSD11B1 hydrogenates PREDN to PREDL in hepatic cell (Gallus gallus)


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Rattus norvegicus)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Canis familiaris)


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Xenopus tropicalis)


name: a tertiary amine + S-adenosyl-L-methionine => a methylated tertiary amine + H(+) + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = (9Z,12Z)-octadecadienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: POLB-mediated DNA strand displacement synthesis (Mus musculus)


name: 6-hydroxyquinolin-2(1H)-one + AH2 => A + H2O + quinolin-6-ol


name: urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR (Bos taurus)


name: 8-chloroquinolin-2(1H)-one + AH2 => 8-chloroquinoline + A + H2O


name: a 1,2-diacyl-sn-glycerol + CDP-choline => a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Caenorhabditis elegans)


name: eNOS:NOSIP translocation from caveolae to intracellular compartments (Plasmodium falciparum)


name: UDP-glucose is oxidised to UDP-glucuronate (Sus scrofa)


name: L-allo-threonine + NADP(+) => (2S)-2-amino-3-oxobutanoate + H(+) + NADPH


name: H(+) + N-methylphenylethanolamine + S-adenosyl-L-homocysteine => phenylethanolamine + S-adenosyl-L-methionine


name: Cytoslic carboxylases translocate to mitochondrial matrix (Bos taurus)


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Gallus gallus)


name: a 3-acyl-sn-glycerol + H2O = a fatty acid + glycerol + H(+)


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (Homo sapiens)


name: ATP + L-leucine + tRNA(Leu) <=> AMP + diphosphate + L-leucyl-tRNA(Leu)


name: AH2 + archaetidylglycerol + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + macrocyclic archaetidylglycerol


name: NCOA1 binds ESR1:estrogen:TGFA gene (Gallus gallus)


name: aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)


name: P2Y2 receptor binds ATP and UTP (Mus musculus)


name: Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)


name: 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine => 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine


name: (2E)-geranyl diphosphate + S-adenosyl-L-methionine <=> (E)-2-methylgeranyl diphosphate + H(+) + S-adenosyl-L-homocysteine


name: CDK1:CCNB phosphorylates NEK9 (Sus scrofa)


name: 2 CO2 + 2 formaldehyde + L-lysyl(36)-[histone H3] + 2 succinate => 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 O2


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate <=> diphosphate + ent-13-epi-manoyl oxide


name: MAPKAPK5 phosphorylates KALRN (Rattus norvegicus)


name: (R)-carnitine(out) + chloride(out) + 2 Na(+)(out) => (R)-carnitine(in) + chloride(in) + 2 Na(+)(in)


name: Further phosphorylation of APC by DCO (Drosophila melanogaster)


name: (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 <=> (E)-2,4-dihydroxycinnamoyl-CoA + CO2 + succinate


name: RNF34 or RFFL ubiquitinates phosphorylated TP53 (Xenopus tropicalis)


name: NAD(+) + propan-2-ol => acetone + H(+) + NADH


name: 4 (R)-3-phenyllactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine = 8 AMP + 8 diphosphate + 8 H(+) + PF1022B + 4 S-adenosyl-L-homocysteine


name: 2-oxoadipate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] <=> CO2 + N(6)-[(R)-S(8)-glutaryldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase]


name: Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Bos taurus)


name: 2 an L-alpha-amino acid => an L-aminoacyl-L-amino acid + H2O


name: GBF1 stimulates nucleotide exchange on ARF (Drosophila melanogaster)


name: (R)-carnitine + H(+) + NADH + O2 = (3R)-3-hydroxy-4-oxobutanoate + H2O + NAD(+) + trimethylamine


name: L-arginine + L-lysine <=> L-homoarginine + L-ornithine


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Danio rerio)


name: 2-oxoglutarate + 4-hydroxy-L-glutamate => 4-hydroxy-2-oxoglutarate + L-glutamate


name: NOTCH1 HD+PEST domain mutants bind JAG2 (Homo sapiens)


name: H2O + mycothiol S-conjugate => 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + an N-acetyl-L-cysteine-S-conjugate


name: enterobactin + H2O => N-(2,3-dihydroxybenzoyl)-L-serine trimer


name: Incorrectly folded glycoproteins translocate to the ERQC (Homo sapiens)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Canis familiaris)


name: UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Rattus norvegicus)


name: ACEIs bind ACE (Drosophila melanogaster)


name: a ubiquinone + H2O + pyruvate <=> a ubiquinol + acetate + CO2


name: an anthocyanidin 3-O-beta-D-sambubioside + UDP-alpha-D-glucose <=> an anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + H(+) + UDP


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O => a 2-acyl-sn-glycero-3-phosphocholine + H(+) + hexanoate


name: 22-hydroxydocosanoate + NAD(+) = 22-oxodocosanoate + H(+) + NADH


name: Active ALK binds JAK3 (Rattus norvegicus)


name: (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-glycerol + H(+) => 1,3-di-(9Z-octadecenoyl)-glycerol + H2O


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Xenopus tropicalis)


name: PGRMC2:Hemes translocate to the nucleus (Caenorhabditis elegans)


name: PNP trimer transforms RBV to T-CONH2 (Canis familiaris)


name: GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate (Sus scrofa)


name: Recruitment and activation of Chk1 (Sus scrofa)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate => alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: PC carboxylates PYR to OA (Xenopus tropicalis)


name: H2O + N-formyl-L-methionine <=> formate + L-methionine


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 O2 => 2 CO2 + 2 formaldehyde + L-lysyl(27)-[histone H3] + 2 succinate


name: 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + dodecanoyl-CoA


name: 1-pyrroline-2-carboxylate + H(+) + NADH => L-proline + NAD(+)


name: FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Sus scrofa)


name: Secretion of transmembrane collagens (Danio rerio)


name: p-PKR dimer phosphorylates MKK6 (Mus musculus)


name: DUOX1,2 reduce O2 to H2O2 (Mus musculus)


name: PRC1 SUMOylates CTBP1 with SUMO1 (Homo sapiens)


name: Transport of SEC22B, TAP and PLC from ER to ERGIC (Rattus norvegicus)


name: 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase]


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe (Drosophila melanogaster)


name: H2O + S-benzyl-L-cysteine = benzylthiol + NH4(+) + pyruvate


name: ATP + H2O + selenate(out) => ADP + H(+) + phosphate + selenate(in)


name: [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + H2O = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + H(+) + methanol


name: 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate => 4-hydroxybenzoate + all-trans-octaprenyl diphosphate


name: ATP + CoA + propanoate = AMP + diphosphate + propanoyl-CoA


name: phosphotransferase activity, for other substituted phosphate groups


name: B4GALT5/6 transfer Gal to GlcCer (Bos taurus)


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Bos taurus)


name: CYP2C19 5-hydroxylates omeprazole (Mus musculus)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Dictyostelium discoideum)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] <=> 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Saccharomyces cerevisiae)


name: 1-chloro-3-nitrobenzene + NADH + O2 = 3-chlorocatechol + NAD(+) + nitrite


name: SUMOylation of PCNA with SUMO1 (Saccharomyces cerevisiae)


name: 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + hexanoyl-sn-glycero-3-phosphoethanolamine => 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 2-heptanoyl-sn-glycero-3-phosphocholine


name: UDP-alpha-D-glucose + validoxylamine A => H(+) + UDP + validamycin A


name: hexanal + hydrogen cyanide => (2S)-2-hydroxyheptanenitrile


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Canis familiaris)


name: A + cannabigerolate = AH2 + cannabichromenate


name: (9Z)-octadecenoate + 2-O-(5Z,8Z,11Z,14Z)-eicosatetraenylglycerol + H(+) => 1-(9Z-octadecenoyl)-2-O-(5Z,8Z,11Z,14Z-eicosatetraenyl)-sn-glycerol + H2O


name: GPX5,6 reduce H2O2 to H2O (Caenorhabditis elegans)


name: diphosphate + viridiflorene => (2E,6E)-farnesyl diphosphate


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Bos taurus)


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA => (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA + H2O


name: devancoaminyl-vancomycin + dTDP-beta-L-vancosamine = dTDP + H(+) + vancomycin


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> (-)-cyatha-3,12-diene + diphosphate


name: 2-epi-5-epi-valiolone + ATP => 2-epi-5-epi-valiolone 7-phosphate + ADP + H(+)


name: TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Mus musculus)


name: alpha-D-glucose 1-phosphate + GDP-beta-L-galactose <=> beta-L-galactose 1-phosphate + GDP-alpha-D-glucose


name: (2R)-3-phosphoglycerate + alpha-D-glucose 1,6-bisphosphate + H(+) => (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole => hapalindole U


name: ATP + beta-alanine + tryptamine => AMP + beta-alanyl-tryptamine + diphosphate + H(+)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Drosophila melanogaster)


name: KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Rattus norvegicus)


name: 3-hydroxy-L-kynurenine(in) + L-tryptophan(out) => 3-hydroxy-L-kynurenine(out) + L-tryptophan(in)


name: (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADH => (1R,2R,4S)-limonene-1,2-diol + NAD(+)


name: (5S)-hydroperoxy-(6E,8Z)-octadecadienoate + 2 glutathione <=> (5S)-hydroxy-(6E,8Z)-octadecadienoate + glutathione disulfide + H2O


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Mus musculus)


name: ethanol + H(+) + hexadecanoate => ethyl hexadecanoate + H2O


name: Prokineticin receptors bind prokineticin (Bos taurus)


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Danio rerio)


name: beta-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+) => alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP-alpha-D-mannose


name: PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Homo sapiens)


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Saccharomyces cerevisiae)


name: SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region (Sus scrofa)


name: all-trans-octaprenyl diphosphate + 5 diphosphate => (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Dictyostelium discoideum)


name: H(+) + NADPH + yaequinolone D <=> H2O + NADP(+) + penigequinolone A


name: a monoacyl-sn-glycero-3-phosphocholine + H2O <=> a monoacylglycerol + H(+) + phosphocholine


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Homo sapiens)


name: O2 + prostaglandin E2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy prostaglandin E2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: dCMP + H2O => dUMP + NH4+ (Mus musculus)


name: 2-oxohexadecanoate + H2O2 => 2-hydroxyhexadecanoate + O2


name: 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA => 8 H(+) + malonamoyl-[OxyC ACP] + 8 malonyl-CoA


name: DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)


name: PLB1 hydrolyses RPALM to atROL (Drosophila melanogaster)


name: LGI3 binds ADAM22,23,synatxin1 (Danio rerio)


name: Co-precorrin-4 + S-adenosyl-L-methionine => Co-precorrin-5A + H(+) + S-adenosyl-L-homocysteine


name: 5-methylcytidine(2870) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(2870) in 25S rRNA + S-adenosyl-L-methionine


name: RAC1 and CDC42 activate PAK1 (Homo sapiens)


name: Synthesis of PIP3 from PIP2 by PI3K (Bos taurus)


name: biuret + H2O => NH4(+) + urea-1-carboxylate


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Caenorhabditis elegans)


name: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Canis familiaris)


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Homo sapiens)


name: Melanocortin receptors bind melanocortins (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecane = 7-tetradecanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Defective CHST6 does not transfer SO4(2-) to GlcNAc residues on keratan-PG (Homo sapiens)


name: SARS-CoV-2 M protein binds MAP1LC3B (Homo sapiens)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Homo sapiens)


name: Autophosphorylation of insulin receptor (Canis familiaris)


name: H(+) + H2O + N(6)-methyl-AMP <=> IMP + methylamine


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Canis familiaris)


name: SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Canis familiaris)


name: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP <=> 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Rattus norvegicus)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Homo sapiens)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH


name: oxidoreductase activity, acting on NAD(P)H


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Homo sapiens)


name: biphenyl-2-ol + H(+) + NADH + O2 => biphenyl-2,3-diol + H2O + NAD(+)


name: 2-hydroxyoctadecanoyl-CoA + sphinganine => CoA + H(+) + N-(2-hydroxyoctadecanoyl)-sphinganine


name: 7-oxopregnenolone + H(+) + NADPH = 7beta-hydroxypregnenolone + NADP(+)


name: ATP + ethanolamine + L-glutamate = ADP + gamma-L-glutamylethanolamide + H(+) + phosphate


name: acetyl-CoA + D-tryptophan <=> CoA + H(+) + N-acetyl-D-tryptophan


name: PPO oxidises PPGEN9 to PRIN9 (Danio rerio)


name: deoxycholate + NAD(+) = 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: dibenzothiophene 5,5-dioxide + FMN-N(5)-peroxide = 2'-hydroxybiphenyl-2-sulfinate + FMN-N(5)-oxide + 2 H(+)


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: (2R)-3-phosphoglycerate + alpha-D-glucose 1,6-bisphosphate + H(+) => (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 6-phosphate


name: Trimming of peptides by IRAP in endocytic vesicles (Canis familiaris)


name: CYP1B1 4-hydroxylates EST17b (Homo sapiens)


name: ACER2 hydrolyzes ceramide (Golgi) (Mus musculus)


name: a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + H2O => a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + diphosphate + H(+)


name: (9Z)-octadecenoate + 2-acetyl-sn-glycero-3-phosphocholine + H(+) => 1-O-(9Z)-octadecenoyl-2-O-acetyl-sn-glycero-3-phosphocholine + H2O


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Gallus gallus)


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Bos taurus)


name: DAXX binds Ub-MDM2 and USP7 (Sus scrofa)


name: LARG activation by G alpha 12/13 (Sus scrofa)


name: (+)-lariciresinol + NADP(+) = (+)-pinoresinol + H(+) + NADPH


name: L-lysyl-L-alpha-amino acid(out) <=> L-lysyl-L-alpha-amino acid(in)


name: cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine <=> aminopropylcadaverine + H(+) + S-methyl-5'-thioadenosine


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Mus musculus)


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Rattus norvegicus)


name: an acyl-CoA + sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: FA anion flip-flops to the opposite surface (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA


name: PHF8 demethylates MeK21-histone H4 (Mus musculus)


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Sus scrofa)


name: Transport of HCMV DNA Into the Nucleus (Homo sapiens)


name: 2-isopropylphenol + H(+) + NADH + O2 = 3-isopropylcatechol + H2O + NAD(+)


name: bromide(out) + chloride(in) => bromide(in) + chloride(out)


name: 4-fumarylacetoacetate + H2O <=> acetoacetate + fumarate + H(+)


name: a (2R,3R)-flavan-3-ol + 2 NAD(+) => an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADH


name: cyclolaudenol + H(+) + S-adenosyl-L-homocysteine => cycloartenol + S-adenosyl-L-methionine


name: 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine => 2,7-dihydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine


name: PI is exchanged with PC by PITPNB (Drosophila melanogaster)


name: 3-oxoheptanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyheptanoyl-[ACP] + NADP(+)


name: (20S)-protopanaxatriol + UDP-alpha-D-glucose = (20S)-ginsenoside F1 + H(+) + UDP


name: mandelate + O2 => H2O2 + phenylglyoxylate


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)


name: 16-hydroxyhexadecanoate + ATP + CoA => 16-hydroxyhexadecanoyl-CoA + AMP + diphosphate


name: Recruitment of VAV and BTK to p-SLP-76 (Canis familiaris)


name: 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate = H2O + monacolin L carboxylate


name: N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Bos taurus)


name: (R)-carnitine + an acyl-CoA => CoA + O-acyl-(R)-carnitine


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Dictyostelium discoideum)


name: (+)-amorpha-4,11-diene + O2 + reduced [NADPH--hemoprotein reductase] = (+)-artemisinic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + an N(1)-methyladenosine in mRNA + O2 = an adenosine in mRNA + CO2 + formaldehyde + succinate


name: Binding of TFIIIC to TFIIIA:Type I Promoter complex  (Dictyostelium discoideum)


name: glycyl-L-aspartate(in) + 2 H(+)(in) => glycyl-L-aspartate(out) + 2 H(+)(out)


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Sus scrofa)


name: 4-coumaroyl-CoA + S-adenosyl-L-methionine = CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine


name: H2O + NADH = AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide


name: ganglioside GM1 (d18:1(4E)/18:0) + N-acetylneuraminate => ganglioside GD1b(d18:1(4E)/18:0) + H2O


name: FGFR3b binds to FGF (Caenorhabditis elegans)


name: [thioredoxin]-dithiol + L-methionine (R)-S-oxide => [thioredoxin]-disulfide + H2O + L-methionine


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Xenopus tropicalis)


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)


name: SERPINC1 binds SERPINC1 activators (Mus musculus)


name: Active ALK binds JAK3 (Canis familiaris)


name: NEK6 and NEK7 phosphorylate EML4 (Gallus gallus)


name: Activated FGFR4 binds FRS2 (Canis familiaris)


name: N-myristoylation of eNOS (Rattus norvegicus)


name: Grb7 binds to the active PDGF receptor (Rattus norvegicus)


name: N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: (R)-3-methyl-2-oxopentanoate + H2O2 + NH4(+) => D-isoleucine + H2O + O2


name: 3-oxopropanoate + H2O + NADP(+) = 2 H(+) + malonate + NADPH


name: L-seryl-[protein] + nonanoyl-CoA = CoA + O-nonanoyl-L-seryl-[protein]


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Plasmodium falciparum)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Danio rerio)


name: JMJD6 demethylates MeR3-histone H3 (Mus musculus)


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 3-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Sulfite is oxidized to sulfate (Mus musculus)


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Canis familiaris)


name: Association of procollagen type XXVII (Canis familiaris)


name: (2E)-dodecenoyl-CoA + H(+) + NADH => dodecanoyl-CoA + NAD(+)


name: aspartic-type endopeptidase inhibitor activity


name: ALB binds extracellular heme (Bos taurus)


name: 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 <=> H2O + NADP(+) + pentalenolactone D


name: rebaudioside A + UDP => rebaudioside B + UDP-alpha-D-glucose


name: (2-oxoindol-3-yl)acetyl-CoA + succinate => 2-oxindole-3-acetate + succinyl-CoA


name: ORC1 binds to H4K20me2 (Dictyostelium discoideum)


name: hexadecanoyl-CoA + serotonin => CoA + H(+) + N-hexadecanoyl-serotonin


name: Oxidation of cholesterol to 22beta-hydroxycholesterol (Canis familiaris)


name: cytidine(40) in tRNA precursor + S-adenosyl-L-methionine = 5-methylcytidine(40) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Homo sapiens)


name: Phosphorylation of RAF (Rattus norvegicus)


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Canis familiaris)


name: HHAT palmitoylates Hh N-terminal fragment (Bos taurus)


name: 2 (2R)-3-phosphoglycerate + 2 H(+) => CO2 + D-ribulose 1,5-bisphosphate + H2O


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Homo sapiens)


name: 3-tetradecanoyl-sn-glycero-1-phospho-(3'-tetradecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol) => 2 3-tetradecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol)


name: 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + A = (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA + AH2


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Homo sapiens)


name: RB1 binds condensin II (Canis familiaris)


name: cholate + NADP(+) <=> 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADPH


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Dictyostelium discoideum)


name: CYP2C19 5-hydroxylates omeprazole (Sus scrofa)


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Rattus norvegicus)


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-L-ribitol <=> 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: RUNX1 binds the SWI/SNF complex (Rattus norvegicus)


name: Autocatalytic activation of proMMP13 (Caenorhabditis elegans)


name: 28-nortyphasterol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => 6-deoxo-28-nortyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: cyclic pyranopterin phosphate + diphosphate => (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate <=> beta-maaliene + diphosphate


name: CHUK, IKBKB phosphorylate CYLD at S418 (Rattus norvegicus)


name: a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol = a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: Superoxide reduces cytochrome c (Canis familiaris)


name: GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Canis familiaris)


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Mus musculus)


name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor


name: ADIPOQ trimer binds ADIPOR dimers (Canis familiaris)


name: Tropoelastin forms aggregate globules (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: 4-aminobutanoate(in) + H(+)(in) = 4-aminobutanoate(out) + H(+)(out)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Rattus norvegicus)


name: 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H(+) + O2 = bracteatin 6-O-beta-glucoside + H2O


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Homo sapiens)


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Schizosaccharomyces pombe)


name: (1R,4R)-dihydrocarvone + H(+) + NADH => (1R,2S,4R)-neodihydrocarveol + NAD(+)


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Homo sapiens)


name: NEK6 and NEK7 phosphorylate EML4 (Caenorhabditis elegans)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Xenopus tropicalis)


name: ADP + H(+) + N-(3-O-phospho-D-ribulosyl)-cadaverine => ATP + N-(D-ribulosyl)-cadaverine


name: 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc => beta-D-Delta(4)-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O


name: hexadecanoyl-CoA + sn-glycerol 3-phosphate <=> 1-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2 H2O = 2 (9Z)-octadecenoate + 2 H(+) + sn-glycerol 3-phosphocholine


name: FOXA1 and GATA3 bind to CCND1 promoter (Bos taurus)


name: Degradation of SMAD2/3:SMAD4 complex (Rattus norvegicus)


name: an N-acyl-(4R)-4-hydroxysphinganine + H2O => (4R)-hydroxysphinganine + a fatty acid


name: The Ligand:GPCR:Gq complex dissociates (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => 4-epi-cubebol + diphosphate


name: ATP7A transports cytosolic Cu2+ to extracellular region (Gallus gallus)


name: H(+) + hydrogencarbonate + methylphosphonate => 2-hydroxyethylphosphonate + O2


name: SUMOylation of RAD52 with SUMO1 (Schizosaccharomyces pombe)


name: CTP + pyruvate => CDP + H(+) + phosphoenolpyruvate


name: 6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + teasterone


name: 3alpha-hydroxy-5alpha-androstane 17-O-(beta-D-glucuronate) + NADP(+) = 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + H(+) + NADPH


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Dictyostelium discoideum)


name: Lactoferrin scavenges iron ions (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate => 1-O-(9Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: XPO1 (CRM1) binds to BACH1:Hemes (Homo sapiens)


name: BTK in active Gq-BTK complex is activated (Rattus norvegicus)


name: glycolate + NADP(+) <=> glyoxylate + H(+) + NADPH


name: MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA (Homo sapiens)


name: Digestion of linear starch (amylose) by extracellular amylase (Gallus gallus)


name: carnosine(out) + 2 H(+)(out) <=> carnosine(in) + 2 H(+)(in)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + stellata-2,6,19-triene <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + stellatate


name: beta-D-fructose 1-phosphate + H2O <=> D-fructose + phosphate


name: (2S,3S)-2-methylcitrate = 2-methyl-cis-aconitate + H2O


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Xenopus tropicalis)


name: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)


name: ALDH3A2-1 oxidises HD2NAL to PALM (Homo sapiens)


name: RSPO:LGR binds ZNRF3 (Rattus norvegicus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Rattus norvegicus)


name: an n-alkanal + NAD(+) => an alk-2-enal + H(+) + NADH


name: H(+) + O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP => trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP-N-acetyl-alpha-D-glucosamine


name: (E)-coniferaldehyde + UDP-alpha-D-glucose <=> 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + H(+) + UDP


name: Phosphorylation of BTK by p-SYK (Sus scrofa)


name: PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Mus musculus)


name: CHOL translocates from lysosome membrane to ER membrane (Dictyostelium discoideum)


name: H2O + N(6)-methyl-ATP <=> diphosphate + H(+) + N(6)-methyl-AMP


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Schizosaccharomyces pombe)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Homo sapiens)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Dictyostelium discoideum)


name: 2 hydrogencarbonate(out) + Zn(2+)(out) <=> 2 hydrogencarbonate(in) + Zn(2+)(in)


name: CYP11B2 oxidises 18HCORST to ALDO (Homo sapiens)


name: SALMs 1-4 bind reticulon 3 (Rattus norvegicus)


name: MIR132 gene expression is stimulated by p-S133-CREB1 (Homo sapiens)


name: 2 AH2 + H(+) + H2O + N2 => 2 A + hydroxylamine + NH4(+)


name: PDPK1 phosphorylates SGK1 (Gallus gallus)


name: FAR1 reduces PalmCoA to HXOL (Bos taurus)


name: cyanidin 3,7-diglucoside glucosidase activity


name: PLK1 phosphorylates NUDC (Plasmodium falciparum)


name: H2O + lactose = beta-D-galactose + D-glucose


name: PDE6 hydrolyses cGMP to GMP (Bos taurus)


name: Cleavage of uracil by MBD4 glycosylase (Canis familiaris)


name: Beta-tubulin:GTP + Cofactor A ->  Beta-tubulin:GTP: Cofactor A (Homo sapiens)


name: CO2 + L-glutamyl-[protein] + O2 + phylloquinol => 2,3-epoxyphylloquinone + 4-carboxy-L-glutamyl-[protein] + H(+) + H2O


name: 1D-myo-inositol 1-phosphate + H2O <=> myo-inositol + phosphate


name: SLC5A6 transports vitamins from extracellular region to cytosol (Mus musculus)


name: H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine = H(+) + N-acyl-15-methylhexadecasphing-4-enine + phosphocholine


name: (E)-ferulate + ATP + CoA => (E)-feruloyl-CoA + AMP + diphosphate


name: (20S)-ginsenoside R1 + H2O = (20S)-ginsenoside Rg1 + D-xylose


name: DIBOA beta-D-glucoside + H(+) + UDP => DIBOA + UDP-alpha-D-glucose


name: ITCH polyubiquitinates TP73 (Bos taurus)


name: A + a primary alcohol = AH2 + an aldehyde


name: HYAL1 hydrolyses (HA)50 (Rattus norvegicus)


name: RAC3 GAPs stimulate RAC3 GTPase activity (Gallus gallus)


name: ATP + thiamine phosphate <=> ADP + thiamine diphosphate


name: a ubiquinol + orotate => (S)-dihydroorotate + a ubiquinone


name: SLCO3A1 isoform 1 has abroad substrate specificity (Sus scrofa)


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Bos taurus)


name: E2F6 binds TFDP2 (Drosophila melanogaster)


name: ETA is phosphorylated to PETA by CHK/ETNK (Plasmodium falciparum)


name: [pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]-phosphate + AMP + H(+)


name: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + UDP-alpha-D-glucuronate <=> an alpha-D-glucuronosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + H(+) + UDP


name: (9Z)-octadecenoyl-CoA + 1-O-hexadecylglycerol = 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA


name: Activated FGFR4 phosphorylates FRS3 (Bos taurus)


name: SUMOylation of NFKBIA with SUMO1 (Gallus gallus)


name: PKR dimer autophosphorylates (Homo sapiens)


name: a 1-acyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-acyl-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: adenosine + phosphate => adenine + alpha-D-ribose 1-phosphate


name: benzoyl-CoA + octan-1-ol = CoA + octyl benzoate


name: 2-methylcholine + CO2 => carnitine + H(+)


name: acetyl-CoA + streptothricin F => CoA + H(+) + N(beta)-acetylstreptothricin F


name: 3-dehydro-6-deoxo-28-norteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 6-dehydro-28-norteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: IL13 binds IL13RA:TYK2 (Rattus norvegicus)


name: Thyroxine is deiodinated to triiodothyronine (Rattus norvegicus)


name: p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Bos taurus)


name: TRAF3IB1 recruits IFT20 to the IFT B complex from the Golgi (Homo sapiens)


name: SREBP1A,1C,2 binds the TM7SF2 promoter (Homo sapiens)


name: a ribonucleoside 5'-triphosphate + AMP <=> a ribonucleoside 5'-diphosphate + ADP


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin] = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycero-3-phosphoglycerol + H2O <=> a 2-acyl-sn-glycero-3-phosphoglycerol + a fatty acid + H(+)


name: acetate + androst-4-ene-3,17-dione + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase]


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Bos taurus)


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate = (1S,5S,6R)-alpha-bergamotene + diphosphate


name: (25S)-3beta-hydroxy-5-cholestenoate + ATP + CoA => (25S)-3beta-hydroxy-5-cholestenoyl-CoA + AMP + diphosphate


name: (9Z)-octadecenoate + 1,3-di-(9Z-octadecenoyl)-glycerol + H(+) => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Schizosaccharomyces pombe)


name: 7,8-dihydroneopterin => 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde


name: MLCL is acylated to CL by HADH (IM) (Mus musculus)


name: Auto ubiquitination of oligo TRAF6 bound to p-IRAK2 (Gallus gallus)


name: The IFT-A complex recruits TULP3 (Sus scrofa)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Xenopus tropicalis)


name: Association of procollagen type VII (Homo sapiens)


name: 3-fumarylpyruvate + H2O <=> fumarate + H(+) + pyruvate


name: 3-oxooctadecanoyl-CoA + H(+) + NADPH = (3R)-hydroxyoctadecanoyl-CoA + NADP(+)


name: Complement factor I binds to membrane-associated Factor H:C3b (Canis familiaris)


name: GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)


name: acetate + L-methionine => H2O + N(alpha)-acetyl-L-methionine


name: a uridine in RNA <=> a pseudouridine in RNA


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Rattus norvegicus)


name: 3-oxohexanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyhexanoyl-[ACP] + NADP(+)


name: Aquaporin-3 passively transports water out of cell (Plasmodium falciparum)


name: PIDD1 translocates to the cytosol (Mus musculus)


name: CYB5Rs reduce MetHb to HbA (Danio rerio)


name: NADP(+) + neomorphine = H(+) + NADPH + neomorphinone


name: F1Fo ATP synthase dimerizes (Mus musculus)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Rattus norvegicus)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Gallus gallus)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Sus scrofa)


name: UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out) <=> UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in)


name: IkB is ubiquitinated and degraded (Rattus norvegicus)


name: Active LTK receptor binds PI3K (Danio rerio)


name: SLC29A1 transports RBV from extracellular region to cytosol (Caenorhabditis elegans)


name: NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP (Canis familiaris)


name: PI3K synthesizes PIP3 downstream of ALK (Caenorhabditis elegans)


name: TP53 and AP-1 bind the MSH2 promoter (Homo sapiens)


name: Elongation of pre-rRNA transcript (Rattus norvegicus)


name: ATP + H2O + rifampicin = 21-phosphorifampicin + AMP + 2 H(+) + phosphate


name: adenosine(out) + H(+)(out) => adenosine(in) + H(+)(in)


name: ATP + CoA + OPC-6 => AMP + diphosphate + OPC-6-CoA


name: H2O + N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Bos taurus)


name: LIPA hydrolyses sterol esters to sterols and fatty acids (Canis familiaris)


name: ANO1 inhibitors bind ANO1 (Mus musculus)


name: [(1->2)-beta-D-glucosyl](n) + H2O = [(1->2)-beta-D-glucosyl](n-2) + sophorose


name: "exo beta-1,2-glucooligosaccharide sophorohydrolase (non-reducing end)"


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Xenopus tropicalis)


name: CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5 (Homo sapiens)


name: AFG3L2 binds mitochondrial matrix proteins (Rattus norvegicus)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains (Canis familiaris)


name: H2O2 + pyridine <=> H2O + pyridine N-oxide


name: agmatine(in) + H(+)(out) => agmatine(out) + H(+)(in)


name: Transphosphorylation of pLIMK1 (Gallus gallus)


name: ATP + L-glutamate + tyramine <=> ADP + gamma-L-glutamyltyramine + H(+) + phosphate


name: Collagen IX is cross-linked to the surface of collagen type II fibrils (Xenopus tropicalis)


name: GBF1 stimulates ARF nucleotide exchange (Bos taurus)


name: C3G stimulates nucleotide exchange on Rap1 (Mus musculus)


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Canis familiaris)


name: ATP + L-amino acyl-L-threonyl-[protein] <=> (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + ADP + H(+) + phosphate


name: Formation of MCM2-7 complex (Caenorhabditis elegans)


name: Activated FGFR3 phosphorylates FRS3 (Canis familiaris)


name: SFTPB,C, PC, PG translocate from lamellar body to extracellular region. (Rattus norvegicus)


name: 2-amino-2-deoxy-D-gluconate <=> 2-dehydro-3-deoxy-D-gluconate + NH4(+)


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Gallus gallus)


name: (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NAD(+) <=> 4-methylsulfanyl-2-oxobutanoate + H(+) + NADH


name: 9-(acyloxy)-octadecanoate + a 2-acylglycerol => 9-hydroxy-octadecanoate + a 1,2-diacyl-sn-glycerol


name: RAC1:GTP binds NOX3 complex (Mus musculus)


name: erinacol + O2 + reduced [NADPH--hemoprotein reductase] = cyathadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH


name: (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+) => (1R,4S)-menthone + H(+) + NADPH + O2


name: FA core complex assembles at DNA interstrand crosslinks (ICLs) (Bos taurus)


name: 10-deacetylbaccatin III 10-O-acetyltransferase activity


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Rattus norvegicus)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Sus scrofa)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA


name: L-methionine(in) + S-methylmercury-L-cysteine(out) = L-methionine(out) + S-methylmercury-L-cysteine(in)


name: SLIT1 binds ROBO1,(ROBO2) (Homo sapiens)


name: TRAF1 is cleaved by caspases (Rattus norvegicus)


name: DHCR24 reduces ZYMOL to ZYMSTNL (Mus musculus)


name: dimethyl sulfide + 2 Fe(III)-[cytochrome c2] + H2O = dimethyl sulfoxide + 2 Fe(II)-[cytochrome c2] + 2 H(+)


name: "dimethyl sulfide:cytochrome c2 reductase"


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Canis familiaris)


name: PRKCB (PKC-beta) phosphorylates CARMA1 (Rattus norvegicus)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Rattus norvegicus)


name: 24-hydroxytetracosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tetracosanoate


name: 2-oxoglutarate + O2 + preaustinoid A1 = CO2 + H2O + preaustinoid A2 + succinate


name: L-histidine + S-adenosyl-L-methionine = (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Caenorhabditis elegans)


name: dopamine + 2 L-ascorbate + O2 = (R)-noradrenaline + H2O + 2 monodehydro-L-ascorbate radical


name: Phosphorylation of BRCA1-A complex at multiple sites by ATM (Gallus gallus)


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Xenopus tropicalis)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Dictyostelium discoideum)


name: Activated FGFR1 phosphorylates PLCG1 (Caenorhabditis elegans)


name: a ganglioside GD3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 + H(+) + UDP


name: Activation of Calcineurin (Dictyostelium discoideum)


name: dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + H(+) + H2O + oxidized [flavodoxin] => dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + reduced [flavodoxin]


name: XPC binds RAD23 and CETN2 (Drosophila melanogaster)


name: AH2 + NH4(+) + O2 => A + H(+) + H2O + hydroxylamine


name: H(+) + indole-3-pyruvate + NADPH + O2 => (indol-3-yl)acetate + CO2 + H2O + NADP(+)


name: a pyrimidine ribonucleoside 5'-phosphate + H2O => a pyrimidine nucleobase + D-ribose 5-phosphate


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Xenopus tropicalis)


name: dGMP + H2O <=> 2'-deoxyguanosine + phosphate


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Rattus norvegicus)


name: IGF2BP1 represses translation of MAPK4 mRNA (Homo sapiens)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Bos taurus)


name: HSF1 acetylation at Lys80 (Rattus norvegicus)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Mus musculus)


name: MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)


name: Laminins:Nidogens binds collagen type IV networks (Sus scrofa)


name: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine => 3,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine


name: SLC44A1 transports Cho from cytosol to mitochondrial matrix (Dictyostelium discoideum)


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) => H(+) + NADH + O2 + phthalate


name: 3-dehydro-6alpha-hydroxyteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3-dehydro-6-deoxoteasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Mus musculus)


name: nocardicin G + S-adenosyl-L-methionine <=> H(+) + isonocardicin C + S-methyl-5'-thioadenosine


name: 2xPDXK:2xZn2+ phosphorylates PXA (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxy-fatty acyl)-dihydroceramide = a 1,2-diacyl-sn-glycerol + inositol-1-phospho-N-(2-hydroxy-fatty acyl)-dihydroceramide


name: GDP-beta-L-fucose + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate <=> GDP + H(+) + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: (6S)-5,6,7,8-tetrahydrofolate + formate + H(+) => (6R)-10-formyltetrahydrofolate + H2O


name: 1-O-salicyl-beta-D-glucose + UDP => salicylate + UDP-alpha-D-glucose


name: (9Z)-octadecenoyl-CoA + eicosan-1-ol <=> 1-O-eicosanyl (9Z)-octadecenoate + CoA


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Canis familiaris)


name: Cdh1:APC/C complex binds EHMT1:EHMT2 (Sus scrofa)


name: ARL2:GTP:ARL2BP binds SLC25A4 (Mus musculus)


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors bind to postsynaptic density proteins (Homo sapiens)


name: Phosphorylation of L1 by CK-II (Mus musculus)


name: luteolin 4',7-dimethyl ether + S-adenosyl-L-homocysteine => diosmetin + S-adenosyl-L-methionine


name: NADP(+) + octadecanoyl-CoA <=> (2E)-octadecenoyl-CoA + H(+) + NADPH


name: 2 H(+) + NADPH + succinate => H2O + NADP(+) + succinate semialdehyde


name: XYLB phosphorylates D-xylulose (Bos taurus)


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Homo sapiens)


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Bos taurus)


name: The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Bos taurus)


name: guanosine(2553) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(2553) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Canis familiaris)


name: INPP5E translocates to the primary cilium (Canis familiaris)


name: Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA (Sus scrofa)


name: D-ribulose 5-phosphate <=> D-xylulose 5-phosphate


name: (S)-cis-N-methyltetrahydropalmatine + O2 + reduced [NADPH--hemoprotein reductase] => 2 H(+) + H2O + muramine + oxidized [NADPH--hemoprotein reductase]


name: chlorophyllide a + 2 H(+) => Mg(2+) + pheophorbide a


name: (20R,22R)-20,22-dihydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 4-methylpentanal + 2 H2O + 2 oxidized [adrenodoxin] + pregnenolone


name: Phosphorylation of MEK7 by MEKK1 (Canis familiaris)


name: malonate(out) + phosphate(in) = malonate(in) + phosphate(out)


name: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate + H(+) => 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate


name: WDR5 binds Me2sR3-replicative histone H3 (Schizosaccharomyces pombe)


name: 3-hydroxybenzyl alcohol + benzoyl-CoA = 3-hydroxy-benzyl benzoate + CoA


name: dimethylallyl diphosphate + hapalindole G = ambiguine A + diphosphate


name: L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose <=> alpha-D-glucosyl-L-tyrosyl-[glycogenin] + H(+) + UDP


name: (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine in DNA <=> a thymidine dimer in DNA


name: ULK1 phosphorylates ATG13 and RB1CC1 (Canis familiaris)


name: all-trans-zeaxanthin + O2 <=> (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Drosophila melanogaster)


name: H(+) + H2O + isoguanine = NH4(+) + xanthine


name: a triacylglycerol + H2O => a 1,2-diacylglycerol + a fatty acid + H(+)


name: Autophosphorylation of PDGFRA extracellular domain dimers (Homo sapiens)


name: Formation of MCM2-7 complex (Bos taurus)


name: a 2-acyl-sn-glycero-3-phosphocholine + H2O <=> a 2-acyl-sn-glycerol 3-phosphate + choline + H(+)


name: asperaculane D + O2 + reduced [NADPH--hemoprotein reductase] = asperaculane E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: A + arsenite + H2O <=> AH2 + arsenate + H(+)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Homo sapiens)


name: (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate => 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2


name: Formation of allysine by LOX (Bos taurus)


name: rifampicin ortho-naphthoquinone carboxamide => rifampicin hemiaminal


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: TCN1 binds correnoids in the circulation (Bos taurus)


name: a 2-hydroxyornithine lipid + CO2 + succinate => 2-oxoglutarate + an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + O2


name: cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Homo sapiens)


name: (2-aminobenzyl)malonyl-CoA + H(+) + O2 => (E)-2-aminocinnamoyl-CoA + CO2 + H2O2


name: Calcineurin binds NFATC1,2,3 (Sus scrofa)


name: NFE2L2 translocates from cytosol to nucleoplasm (Mus musculus)


name: 1-hexadecanoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + 10-hydroperoxy-(8E)-octadecenoate + H(+)


name: a 5-methylcytidine in 25S rRNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in 25S rRNA + S-adenosyl-L-methionine


name: 2 Fe(II)-[cytochrome c] + formate + 3 H(+) => 2 Fe(III)-[cytochrome c] + formaldehyde + H2O


name: HK1 phosphorylates Mannose to Man6P (Canis familiaris)


name: a thymidine in DNA + NAD(+) => an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H(+) + nicotinamide


name: L-Glutamine transport into neurons (Canis familiaris)


name: H2O + NAD(+) + salicylaldehyde => 2 H(+) + NADH + salicylate


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Rattus norvegicus)


name: calciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = calcidiol + H2O + 2 oxidized [adrenodoxin]


name: D-ribonate => 2-dehydro-3-deoxy-D-arabinonate + H2O


name: RNF41 ubiquitinates activated ERBB3 (Gallus gallus)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Drosophila melanogaster)


name: Expression of CD36 (platelet glycoprotein IV, FAT) (Homo sapiens)


name: 2xPPCS ligates PPanK with Cys (Caenorhabditis elegans)


name: ADP + D-ribulose 5-phosphate + H(+) => ATP + D-ribulose


name: Haptoglobin:Hemoglobin binds CD163 (Homo sapiens)


name: a 1-acyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) => a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2


name: meso-2,6-diaminoheptanedioate + NADP(+) = (S)-2,3,4,5-tetrahydrodipicolinate + 2 H(+) + NADPH + NH4(+)


name: 2 Fe(III)-[cytochrome c2] + NADPH => 2 Fe(II)-[cytochrome c2] + H(+) + NADP(+)


name: HSD17B3-like proteins reducde ANDST to TEST (Caenorhabditis elegans)


name: ATP + L-glutamate + spermidine = ADP + gamma-L-glutamylspermidine + H(+) + phosphate


name: chylomicron remnant + apoE => chylomicron remnant:apoE complex (Canis familiaris)


name: 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphate + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + octadecanoyl-CoA


name: D-cycloserine(in) + H(+)(in) <=> D-cycloserine(out) + H(+)(out)


name: 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose => 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+)


name: Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Xenopus tropicalis)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphate


name: 6-hydroxy pseudo-oxynicotine monooxygenase activity


name: 2 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) = 2 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: GPCR neuropeptide receptor binds neuropeptides B and W (Rattus norvegicus)


name: alpha-D-mannosyl-(1->3)-alpha-D-galactosyl-diphospho-di-trans,octa-cis-undecaprenol + GDP-alpha-D-mannose = alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: D-glucose + N-octadecanoylsphing-4-enine => beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + H2O


name: Release of activated MAD2 from kinetochores (Mus musculus)


name: H(+) + L-methionyl(47)-[F-actin] + NADPH + O2 <=> H2O + L-methionyl(47)-(R)-S-oxide-[F-actin] + NADP(+)


name: Tyrosinase oxidises tyrosine to dopaquinone (Rattus norvegicus)


name: 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] (Homo sapiens)


name: acetyl-AMP + cytidine(34) in elongator tRNA(Met) => AMP + H(+) + N(4)-acetylcytidine(34) in elongator tRNA(Met)


name: SLC29A1 transports RBV from cytosol to extracellular region (Bos taurus)


name: COP9 and TOR1 deneddylate STON2 (Drosophila melanogaster)


name: decarboxylation-driven active transmembrane transporter activity


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Xenopus tropicalis)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Bos taurus)


name: BRF1 Complex recruits RNA degradation activities (Caenorhabditis elegans)


name: MDM2 translocates to the cytosol (Rattus norvegicus)


name: GTSE1 promotes translocation of TP53 to the cytosol (Rattus norvegicus)


name: Binding of cAMP to HCN channels (Rattus norvegicus)


name: AVPR1A,2 bind AVPR antagonists (Mus musculus)


name: dUTP + H2O => dUMP + pyrophosphate (Schizosaccharomyces pombe)


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an R-cob(III)alamin(in) <=> an R-cob(III)alamin(out)


name: S-(2,3-dicarboxypropyl)-L-cysteinyl-[protein] => itaconate + L-cysteinyl-[protein]


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Homo sapiens)


name: eriodictyol-7-O-beta-D-glucoside + H2O <=> (S)-eriodictyol + beta-D-glucose


name: GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O


name: Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Bos taurus)


name: acetate + H(+) + O-ureido-L-serine => hydroxyurea + O-acetyl-L-serine


name: Anti-MET small tyrosine kinase inhibitors bind MET (Mus musculus)


name: IRAK interacts with TRAF6 (Canis familiaris)


name: H2O + L-serine + O2 = 3-hydroxypyruvate + H2O2 + NH4(+)


name: ABC-type oligosaccharide transporter activity


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Homo sapiens)


name: PINK1 phosphorylates PRKN at S65 (Rattus norvegicus)


name: Activation of HCN channels (Xenopus tropicalis)


name: MAVS interacts with RIPK1 and FADD (Homo sapiens)


name: PLA2G2A binds bacterial phospholipids (Sus scrofa)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)


name: D-sorbitol + NADP(+) = H(+) + keto-L-sorbose + NADPH


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Rattus norvegicus)


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Sus scrofa)


name: TP53 binds the RABGGTA gene (Homo sapiens)


name: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + A => (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + AH2


name: AKT phosphorylates FOXO3 downstream of ESR1 and EGFR (Mus musculus)


name: Hemoglobin A binds O2, releasing H+ and CO2 (Mus musculus)


name: L-isoleucine + neocasomorphin-(1-5) => H2O + neocasomorphin


name: 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O


name: Cleavage of ethenocytosine by TDG glycosylase  (Canis familiaris)


name: Binding of RRN3 to RNA Polymerase I (Caenorhabditis elegans)


name: THEM86B hydrolyses PMCHO, PMETAM (Dictyostelium discoideum)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Canis familiaris)


name: inositol diphosphate tetrakisphosphate kinase activity


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Sus scrofa)


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Dictyostelium discoideum)


name: Conjugation of SUMO1 to UBA2:SAE1 (Rattus norvegicus)


name: nicotinate(in) + urate(out) => nicotinate(out) + urate(in)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Rattus norvegicus)


name: Complexed PIWIL2:2'-O-methyl-piRNA cleaves transposon RNA (Homo sapiens)


name: Laminins bind Nidogens 1, 2 (Homo sapiens)


name: Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding (Homo sapiens)


name: IL6R binds IL6R inhibitors (Rattus norvegicus)


name: Initial activation of proMMP2 by MMP1, 7 (Xenopus tropicalis)


name: RAPGEF1 activates RAP1 (Canis familiaris)


name: Regulation of KIF20A (MKL2) by phosphorylation (Danio rerio)


name: 4-nitrobenzaldehyde + H(+) + NADPH <=> 4-nitrobenzyl alcohol + NADP(+)


name: SLC38A9 binds Ragulator:Rag dimers (Homo sapiens)


name: 2-oxoheptanedioate + acetyl-CoA + H2O <=> (R)-trihomocitrate + CoA + H(+)


name: ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate


name: H2O + L-saccharopine + O2 = (S)-2-amino-6-oxohexanoate + H2O2 + L-glutamate


name: SIRT1 deacetylates HINT1 dimer (Sus scrofa)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Dictyostelium discoideum)


name: 4-methoxybenzoate + ATP + H(+) + NADPH => 4-methoxybenzaldehyde + AMP + diphosphate + NADP(+)


name: (-)-medicarpin + H2O => (3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol


name: BAP1 binds BRCA1:BARD1 heterodimer (Sus scrofa)


name: acetylpyruvate + H2O <=> acetate + H(+) + pyruvate


name: a long-chain fatty acid(in) => a long-chain fatty acid(out)


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Homo sapiens)


name: ATP + L-glutamate + spermidine => ADP + gamma-L-glutamylspermidine + H(+) + phosphate


name: NIPAs transport Mg2+ from extracellular region to cytosol (Bos taurus)


name: CES1 hydrolyses sacubitril to sacubitrilat (Xenopus tropicalis)


name: ADK phosphorylates RBV (Saccharomyces cerevisiae)


name: a 16alpha-hydroxysteroid + NAD(+) = a 16-oxosteroid + H(+) + NADH


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Gallus gallus)


name: The phagophore extends from the PIP3-enriched structure (Homo sapiens)


name: NEIL2 cleaves 5-OHU from damaged DNA (Gallus gallus)


name: 2,2-dihydroxyspheroidene = H2O + spheroiden-2-one


name: Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Drosophila melanogaster)


name: H2O + methanethiol + O2 = formaldehyde + H(+) + H2O2 + hydrogen sulfide


name: bacterioruberin = bisanhydrobacterioruberin + 2 H2O


name: FOXO4:ATXN3 binds SOD2 gene promoter (Homo sapiens)


name: Cleavage of p-STK3 (p-MST2) by caspase 3 (Bos taurus)


name: 4 CO2 + 4 CoA + dihydropinosylvin => 3-phenylpropanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Xenopus tropicalis)


name: ATP + cob(I)yrinate a,c diamide-[corrinoid adenosyltransferase] => adenosylcob(III)yrinate a,c-diamide + apo-[corrinoid adenosyltransferase] + triphosphate


name: 2-chlorobenzoate + H(+) + NADH + O2 = catechol + chloride + CO2 + NAD(+)


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Caenorhabditis elegans)


name: CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein] => (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein]


name: ACP6 hydrolyses MYS-LPA (Rattus norvegicus)


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 = 1-O-methyl-(9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Bos taurus)


name: 3'-dehydromaltose + H2O <=> 3-dehydro-D-glucose + D-glucose


name: H(+)(out) + taurine(out) => H(+)(in) + taurine(in)


name: Active ALK binds PLCG1 (Rattus norvegicus)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + H2O => (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + D-glucuronate + H(+)


name: PGR binds PGR antagonists (Rattus norvegicus)


name: inositol pentakisphosphate phosphatase activity


name: SUMOylation of DDX17 with SUMO1 (Schizosaccharomyces pombe)


name: ADA catalyzes the deamination of (deoxy)adenosine (Caenorhabditis elegans)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Rattus norvegicus)


name: H(+) + O-phospho-L-threonine <=> (R)-1-aminopropan-2-yl phosphate + CO2


name: SUMOylation of DDX17 with SUMO1 (Rattus norvegicus)


name: 12alpha,13alpha-dihydroxyfumitremorgin C + dimethylallyl diphosphate <=> diphosphate + fumitremorgin B


name: ATP + CoA + propanoate <=> ADP + phosphate + propanoyl-CoA


name: Formation of hair keratin fibres (Bos taurus)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + H(+)(in) => (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + H(+)(out)


name: 2-oxoglutarate + L-arginyl-[ribosomal protein uL16] + O2 <=> (3R)-3-hydroxy-L-arginyl-[ribosomal protein uL16] + CO2 + succinate


name: MLH1:PMS2 makes single strand incision near  insertion/deletion loop of 2 bases or more (Homo sapiens)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Xenopus tropicalis)


name: histone H3K79 monomethyltransferase activity


name: L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: DEGS1 dehydrogenates dihydroceramide (Rattus norvegicus)


name: 2 Fe(III)-[cytochrome c] + H2O + octanal = 2 Fe(II)-[cytochrome c] + 3 H(+) + octanoate


name: fusidate(out) + H(+)(in) => fusidate(in) + H(+)(out)


name: Expression of peptide bound class I MHC on cell surface (Sus scrofa)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Homo sapiens)


name: 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Bos taurus)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Plasmodium falciparum)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Mus musculus)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Xenopus tropicalis)


name: a ganglioside GM1 (d18:1(4E)) + H2O <=> a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate


name: Arachidonic acid is oxidised to 12R-HpETE by ALOX12B (Bos taurus)


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Xenopus tropicalis)


name: (S)-nicotine + O2 + reduced [NADPH--hemoprotein reductase] => (S)-nornicotine + formaldehyde + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate <=> 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: protein tyrosine phosphatase activity, metal-dependent


name: 4-(hydroxymethyl)benzenesulfonate + NAD(+) => 4-formylbenzenesulfonate + H(+) + NADH


name: SFTPAs translocate from ER membrane to extracellular region (Bos taurus)


name: MAPK1 phosphorylates SOX10 (Drosophila melanogaster)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Plasmodium falciparum)


name: 16-hydroxy-ilicicolin A epoxide + H2O + NADP(+) => H(+) + ilicicolin A epoxide + NADPH + O2


name: 3-oxooctanedioyl-CoA + CoA = acetyl-CoA + hexanedioyl-CoA


name: p-S215 FOXO3 translocates to the nucleus (Canis familiaris)


name: 5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine


name: DCN (decorin) degradation by MMP14 (Rattus norvegicus)


name: Formation of eEF1B complex (Rattus norvegicus)


name: I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol (Homo sapiens)


name: SOS mediated nucleotide exchange of RAS (SHC) (Gallus gallus)


name: Translocation of NuMA to the centrosomes (Gallus gallus)


name: H(+) + hexadecanoate + hnu = CO2 + pentadecane


name: cGMP stimulates Protein Kinase G (Homo sapiens)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Homo sapiens)


name: CoA + H(+) + N-terminal N-acetyl-L-(Asp/Glu)3-[protein] => acetyl-CoA + N-terminal L-(Asp/Glu)3-[protein]


name: BRF1 Complex recruits RNA degradation activities (Bos taurus)


name: O2 + prostaglandin E2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy prostaglandin E2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = adenosine 3',5'-bisphosphate + 2 H(+) + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine


name: L-glutamine(out) + L-serine(in) + Na(+)(out) => L-glutamine(in) + L-serine(out) + Na(+)(in)


name: dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Xenopus tropicalis)


name: ATP + L-seryl-[isocitrate dehydrogenase] <=> ADP + H(+) + O-phospho-L-seryl-[isocitrate dehydrogenase]


name: SULT1A1 dimer sulfonates NHABP (Mus musculus)


name: HOXD4 gene is transcribed (Homo sapiens)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Dictyostelium discoideum)


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Rattus norvegicus)


name: mitomycin A + S-adenosyl-L-homocysteine => 6-demethylmitomycin A + S-adenosyl-L-methionine


name: butanoyl-CoA + NADP(+) = (2E)-butenoyl-CoA + H(+) + NADPH


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[(9R,10S)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: F2R:ARRB1 binds MAPKs, SRC-1 (Danio rerio)


name: coproporphyrinogen III + 3 O2 => coproporphyrin III + 3 H2O2


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Mus musculus)


name: Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. (Canis familiaris)


name: butanoyl-CoA + H(+) + NADH => butanal + CoA + NAD(+)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Rattus norvegicus)


name: calcidiol 3-O-(beta-D-glucuronide) + H(+) + UDP => calcidiol + UDP-alpha-D-glucuronate


name: (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O => pyruvate + salicylaldehyde


name: (+)-artemisinic aldehyde + O2 + reduced [NADPH--hemoprotein reductase] => (+)-artemisinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Canis familiaris)


name: RTC synthesizes SARS-CoV-2 plus strand genomic RNA (Homo sapiens)


name: biliverdin IXalpha + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin] => 15,16-dihydrobiliverdin + oxidized 2[4Fe-4S]-[ferredoxin]


name: NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a fatty acid + H(+)


name: 4,4-dihydroxy-all-trans-beta-carotene = echinenone + H2O


name: FLT mutants bind type II TKIs (Homo sapiens)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN2D (GRIN2D) (Homo sapiens)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Rattus norvegicus)


name: Formation of TSC1:TSC2 complex (Homo sapiens)


name: A + H2O + resolvin E2 => (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2


name: bergapten + S-adenosyl-L-homocysteine => bergaptol + S-adenosyl-L-methionine


name: ADP + beta-L-fucose 1-phosphate + H(+) => ATP + L-fucose


name: MET bound PI3K generates PIP3 (Caenorhabditis elegans)


name: Formation of the MCC complex (Schizosaccharomyces pombe)


name: 2-methylanisole + O2 + reduced [NADH--hemoprotein reductase] = 2-hydroxytoluene + formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Canis familiaris)


name: 2 a ubiquinol + 4 H(+)(in) + O2(in) = 2 a ubiquinone + 4 H(+)(out) + 2 H2O(in)


name: "ubiquinol oxidase (electrogenic, proton-motive force generating)"


name: H2O + 2 O2 + sym-homospermidine <=> 1-formylpyrrolizidine + 2 H2O2 + 2 NH4(+)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Xenopus tropicalis)


name: glyoxylate + H2O + propanoyl-CoA => 2-hydroxyglutarate + CoA + H(+)


name: KAT5 acetylates ATM at shortened telomeres (Gallus gallus)


name: Neurotensin receptors can bind neurotensins (Homo sapiens)


name: MARC1,MARC2 reduce N-hydroxylated compounds (Caenorhabditis elegans)


name: D-ribulose 5-phosphate + L-tryptophan => (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + formaldehyde + H(+) + H2O + hydroxyacetone + phosphate


name: (2Z,6E)-farnesyl diphosphate => (E)-beta-farnesene + diphosphate


name: SLC17A3-2 transports cytosolic urate to extracellular region (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ethanolamine => H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: 25-substituted-cholesterol + beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine <=> 25-substituted-cholesteryl beta-D-glucoside + N-hexadecanoylsphing-4-enine


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Rattus norvegicus)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 16beta,17beta-estriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 11-dehydrocorticosterone + NAD(+) <=> H(+) + NADH + pregn-4-ene-3,11,20,21-tetraone


name: 12-(phosphooxy)octadecanoate + H2O => 12-hydroxyoctadecanoate + phosphate


name: [thioredoxin]-disulfide + prostaglandin F2alpha => [thioredoxin]-dithiol + prostaglandin H2


name: D-mannitol + phosphate => D-mannitol 1-phosphate + H2O


name: 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O => 4-oxohex-2-enedioate + H(+)


name: an S-(2-hydroxyacyl)glutathione + H2O <=> a 2-hydroxy carboxylate + glutathione + H(+)


name: 15-cis-phytoene + A = AH2 + all-trans-phytofluene


name: IFNG dimer binds IFNG inhibitors (Rattus norvegicus)


name: 2-oxoglutarate + gibberellin A1 + O2 = CO2 + gibberellin A8 + succinate


name: D-glucose(out) + 2 Na(+)(out) => D-glucose(in) + 2 Na(+)(in)


name: guanosine(in) + 2 Na(+)(in) => guanosine(out) + 2 Na(+)(out)


name: H(+) + N(alpha)-methyl-L-histidine + S-adenosyl-L-homocysteine => L-histidine + S-adenosyl-L-methionine


name: L-asparagine(in) + L-glutamine(out) + Na(+)(out) = L-asparagine(out) + L-glutamine(in) + Na(+)(in)


name: Collagen type III degradation by MMP14 (Xenopus tropicalis)


name: Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Drosophila melanogaster)


name: Crk binds to the active PDGF receptor (Gallus gallus)


name: diphosphate + peniprequinolone => dimethylallyl diphosphate + quinolinone B


name: 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one (Drosophila melanogaster)


name: Phosphorylation of L1 by SRC (Homo sapiens)


name: STAT1,STAT3,STAT6 bind IL13:IL13R type II (Rattus norvegicus)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Rattus norvegicus)


name: 1-acyl LPG is acylated to PG by LPGAT (Sus scrofa)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Xenopus tropicalis)


name: Interaction of IQGAP1 with nephrin (Homo sapiens)


name: 9-cis-retinal + H(+) + NADH => 9-cis-retinol + NAD(+)


name: (E)-feruloyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] => CoA + H(+) + myricetin 3-O-[(6-O-[(E)-feruloyl]-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Rattus norvegicus)


name: beta-D-fructose 1,6-bisphosphate + methylglyoxal = 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + D-glyceraldehyde 3-phosphate


name: CoA + H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + 2-hydroxyhexacosanoyl-CoA


name: (2E)-octenoyl-CoA + H2O => 3-hydroxyoctanoyl-CoA


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)


name: Dimerization of STATs downstream of KIT mutants (Homo sapiens)


name: beta-D-fructose 2,6-bisphosphate + H2O <=> beta-D-fructose 2-phosphate + phosphate


name: Formation of lysyl-pyrrole cross-links (Caenorhabditis elegans)


name: NEIL1 cleaves DHU from damaged DNA (Rattus norvegicus)


name: 2-oxoglutarate + glycine = glyoxylate + L-glutamate


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GA2 (d18:1(4E)) + H(+) + UDP


name: (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside(in) + ATP + H2O <=> (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside(out) + ADP + H(+) + phosphate


name: 1,5-anhydro-D-fructose <=> ascopyrone M + H2O


name: Monoubiquitinated PTEN translocates to the nucleus (Canis familiaris)


name: AXIN is ubiquitinated by SMURF2 (Bos taurus)


name: (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate <=> sulfate + sulforaphane


name: aldehyde dehydrogenase [NAD(P)+] activity


name: CTP + 2 H2O <=> CMP + 2 H(+) + 2 phosphate


name: Keratin type I/type II heterodimers form tetramers (Rattus norvegicus)


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Rattus norvegicus)


name: Fibulin binds elastic fibres (Rattus norvegicus)


name: H2O + meso-2,6-diaminoheptanedioate + NADP(+) => (S)-2-amino-6-oxoheptanedioate + H(+) + NADPH + NH4(+)


name: H(+) + oxidized [electron-transfer flavoprotein] + pentanoyl-CoA <=> (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]


name: SMURF1 ubiquitinates RHOA (Drosophila melanogaster)


name: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a 2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Mus musculus)


name: 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO => O2 + quercetin


name: H2O + P(1),P(6)-bis(5'-adenosyl) hexaphosphate = adenosine 5'-tetraphosphate + ADP + 2 H(+)


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Homo sapiens)


name: Spherical HDL binds C and E apolipoproteins (Rattus norvegicus)


name: UDP-N-acetyl-alpha-D-glucosamine => H2O + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose


name: acetyl-CoA + L-methionine <=> CoA + H(+) + N(alpha)-acetyl-L-methionine


name: STAT3 phosphorylation (Canis familiaris)


name: Cho is acetylated to AcCho by CHAT (Canis familiaris)


name: D-glyceraldehyde 3-phosphate + NADP(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADPH


name: (3R)-3-hydroxybutanoyl-CoA + H2O <=> (R)-3-hydroxybutanoate + CoA + H(+)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Bos taurus)


name: Recruitment of SLP-76 to Gads (Sus scrofa)


name: NQO1 interaction with ODC (Xenopus tropicalis)


name: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Bos taurus)


name: H2O + hexanal + O2 => H(+) + H2O2 + hexanoate


name: CDP-choline + sphing-4-enine <=> CMP + H(+) + sphing-4-enine-phosphocholine


name: 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine + AH2 <=> 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine + A + H2O


name: The Ligand:GPCR:Gi complex dissociates (Gallus gallus)


name: 4 H(+) + narbomycin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + novapikromycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)


name: 2-oxoglutarate + chloride + H(+) + L-threonyl-[peptidyl-carrier protein] + O2 <=> 4-chloro-L-threonyl-[peptidyl-carrier protein] + CO2 + H2O + succinate


name: 10-hydroxy-(11S,12S)-epoxy- (5Z,8Z,14Z)-eicosatrienoate + H2O => (10,11S,12R)-trihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: abacavir [extracellular] => abacavir [cytosol] (Bos taurus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Dictyostelium discoideum)


name: H2O + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> (9Z)-octadecenoate + H(+) + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: Binding of STAT1 to p-IFNGR1 (Sus scrofa)


name: G alpha (q) binds to Trio family RhoGEFs (Gallus gallus)


name: acetyl-CoA + cyathatriol = 11-O-acetylcyathatriol + CoA


name: beta-D-galacturonate + NAD(+) = D-galactaro-1,5-lactone + H(+) + NADH


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Danio rerio)


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Rattus norvegicus)


name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate (Danio rerio)


name: O2 + reduced [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + an N(1)-ethyl-2'-deoxyadenosine in single-stranded DNA + O2 <=> a 2'-deoxyadenosine in single-stranded DNA + acetaldehyde + CO2 + H(+) + succinate


name: calycosin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => formononetin + O2 + reduced [NADPH--hemoprotein reductase]


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Canis familiaris)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Mus musculus)