name: 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: cyanophycin synthetase activity (L-arginine-adding)


name: ULK complex translocates to the ER (Dictyostelium discoideum)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Drosophila melanogaster)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Gallus gallus)


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Plasmodium falciparum)


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] => H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein]


name: Caspase-mediated cleavage of Rock-1 (Mus musculus)


name: Class IV antihypertensives bind LTCC multimer (Drosophila melanogaster)


name: CaMKK autophosphorylates in the cytosol (Schizosaccharomyces pombe)


name: PIP3 binds to RhoA and activates it (Xenopus tropicalis)


name: eburicol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 14-demethyleburicol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: GM-CSF receptor alpha:GM-CSF binds Bc (Canis familiaris)


name: linear maltodextrin => cyclomaltodextrin + H2O


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Xenopus tropicalis)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Rattus norvegicus)


name: I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 (Homo sapiens)


name: H2O + N-acetyltyramine <=> acetate + tyramine


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphate <=> a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: H(+) + 2 monodehydro-L-ascorbate radical + NADH => 2 L-ascorbate + NAD(+)


name: calcidiol + UDP-alpha-D-glucuronate => calcidiol 3-O-(beta-D-glucuronide) + H(+) + UDP


name: DDHD1,2 hydrolyse PA (Dictyostelium discoideum)


name: (17R,20S)-17,20-dihydroxypregn-4-en-3-one + NADP(+) <=> 17alpha-hydroxyprogesterone + H(+) + NADPH


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Homo sapiens)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] (Mus musculus)


name: SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Bos taurus)


name: PPM1A dephosphorylates nuclear SMAD2/3 (Homo sapiens)


name: RRAGC,D exchanges GTP for GDP (Rattus norvegicus)


name: Benzene is hydroxylated to phenol (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + germacrene A


name: mRNA 5'-cap (guanine-N7-)-methyltransferase activity


name: 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Caenorhabditis elegans)


name: snRNP nuclear import and release (Canis familiaris)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Caenorhabditis elegans)


name: apulose 4-phosphate + D-glyceraldehyde 3-phosphate => D-xylulose 5-phosphate + dihydroxyacetone phosphate


name: H2O + methylguanidine => methylamine + urea


name: a 5'-end triphospho-adenosine in mRNA + H2O <=> a 5'-end diphospho-adenosine in mRNA + H(+) + phosphate


name: AKT phosphorylates IKKalpha (Gallus gallus)


name: butanoate + NAD(+) => (2E)-2-butenoate + H(+) + NADH


name: Complement factor I binds to MCP, CR1:C4b, C3b (Gallus gallus)


name: RPE dimers isomerise RU5P to XY5P (Caenorhabditis elegans)


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Caenorhabditis elegans)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine <=> 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA


name: 2 (S)-lactate(in) + prostaglandin F2alpha(out) = 2 (S)-lactate(out) + prostaglandin F2alpha(in)


name: PLK1 phosphorylates GORASP1 (Saccharomyces cerevisiae)


name: PEX7 binds cargo proteins containing PTS2 (Danio rerio)


name: a 2-oxocarboxylate + L-ornithine = an L-alpha-amino acid + L-glutamate 5-semialdehyde


name: H2O + UDP-alpha-D-glucose => alpha-D-galactose 1-phosphate + 2 H(+) + UMP


name: p-Y516 of p-5Y-NTRK2 recruits SHC1 (Homo sapiens)


name: 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 H(+) + 2 phosphate


name: H2O + N-(9Z-octadecenoyl)-L-isoleucine => (9Z)-octadecenoate + L-isoleucine


name: eNOS translocation from Golgi to Caveolae (Schizosaccharomyces pombe)


name: cytochrome-b5 reductase activity, acting on NADH


name: RNF152 polyubiquitinates RRAGA (Bos taurus)


name: AURKA phosphorylates TP53 (Canis familiaris)


name: RHOQ translocates to the Golgi-associated vesicle membranes (Homo sapiens)


name: 15,17(3)-seco-F430-17(3)-acid + ATP => ADP + coenzyme F430 + phosphate


name: Interaction of other tyrosine kinases with p-KIT (Rattus norvegicus)


name: dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA (Sus scrofa)


name: diphosphate + L-threonyl-5'-AMP => ATP + L-threonine


name: Palmostatin B binds RAS depalmitoylases (Homo sapiens)


name: an acyl-CoA + sn-glycerol 3-phosphate <=> a 2-acyl-sn-glycerol 3-phosphate + CoA


name: indolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] => 3-hydroxyindolin-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-O-(1Z-hexadecenyl)-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH = 1-O-(1Z-hexadecenyl)-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: FKBP1A binds sirolimus (Caenorhabditis elegans)


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Canis familiaris)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol => an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside


name: 10-hydroxydecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => decanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: NQO1 interaction with ODC (Rattus norvegicus)


name: (3R)-hydroxy-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA <=> (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H2O


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Drosophila melanogaster)


name: Ubiquitinated TP53 translocates to the cytosol (Homo sapiens)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Mus musculus)


name: 2,3-dihydrobiochanin A + NADP(+) = biochanin A + 2 H(+) + NADPH


name: Cleavage of ethenoadenine by MPG glycosylase (Rattus norvegicus)


name: 3-(4-hydroxyphenyl)pyruvate + O2 <=> (S)-4-hydroxymandelate + CO2


name: PEX19:class I PMP binds PEX3 (Caenorhabditis elegans)


name: Active FLT3 binds to GRAP2 (Canis familiaris)


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Bos taurus)


name: cob(II)alamin-[corrinoid adenosyltransferase] => apo-[corrinoid adenosyltransferase] + cob(II)alamin


name: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H(+) + rebeccamycin + S-adenosyl-L-homocysteine


name: DECR2 reduces LCtE-CoA to t3enoyl-CoA (Saccharomyces cerevisiae)


name: (R)-3-phosphomevalonate + ATP <=> (R)-3,5-bisphosphomevalonate + ADP + H(+)


name: BTN2A2 binds T cell surface (Gallus gallus)


name: Importin-8 imports AGO2:miRNA into the nucleus (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: gibberellin A12 + 5 H(+) + 3 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> CO2 + gibberellin A9 + 4 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: eNOS synthesizes NO (Saccharomyces cerevisiae)


name: EXT1:EXT2 transfers GlcA to heparan (Rattus norvegicus)


name: Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Mus musculus)


name: Platelet-derived TREM-1 ligand binds to TREM-1 (Canis familiaris)


name: an anilide + H2O <=> a carboxylate + aniline + H(+)


name: Formation of pre-mRNPs (Rattus norvegicus)


name: Aquaporin-1 passively transports water out of cell (Canis familiaris)


name: Calcineurin binds and dephosphorylates NFAT (Mus musculus)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Schizosaccharomyces pombe)


name: 2-aminobut-2-enoate + H2O => L-homoserine


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Rattus norvegicus)


name: Recruitment of PLC-gamma1 to SLP-76 (Canis familiaris)


name: glutarate(out) + prostaglandin F2alpha(in) => glutarate(in) + prostaglandin F2alpha(out)


name: 1-O-methyl-(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatrienoate => 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: D-tyrosine + H2O + O2 = 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: 1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + octanoate


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Dictyostelium discoideum)


name: AFG3L2 binds mitochondrial matrix proteins (Bos taurus)


name: (Z)-desulfoglucotropeolin + UDP => (Z)-2-phenyl-1-thioacetohydroximate + UDP-alpha-D-glucose


name: 4-hydroxybenzoyl-5'-AMP + diphosphate => 4-hydroxybenzoate + ATP + H(+)


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Homo sapiens)


name: 16 ADP + 18 H(+) + H2 + 2 NH4(+) + 4 oxidized [flavodoxin] + 16 phosphate => 16 ATP + 16 H2O + N2 + 4 reduced [flavodoxin]


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Dictyostelium discoideum)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Homo sapiens)


name: 2-hydroxyhexanoate + O2 = 2-oxohexanoate + H2O2


name: Release of E3 from polyubiquitinated substrate (Bos taurus)


name: 3,4-dihydroxyphenylethyleneglycol + NAD(+) = 3,4-dihydroxymandelaldehyde + H(+) + NADH


name: a long-chain fatty acyl-CoA + H2O <=> a long-chain fatty acid + CoA + H(+)


name: H2O + hexylamine + NAD(+) => H(+) + hexanal + NADH + NH4(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: NADP(+) + octadecanoyl-CoA => (2E)-octadecenoyl-CoA + H(+) + NADPH


name: SCD desaturates ST-CoA to OLE-CoA (Plasmodium falciparum)


name: Dissociation of phospho-Cdh1 from the APC/C complex (Bos taurus)


name: FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4 (Homo sapiens)


name: RAC2 translocates to the mitochondrial membrane (Drosophila melanogaster)


name: MLKL binds IP4, IP5 and IP6  (Mus musculus)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O


name: 7beta-hydroxycholesterol(out) + ADP + H(+) + phosphate => 7beta-hydroxycholesterol(in) + ATP + H2O


name: Collagen type XIII ectodomain shedding (Homo sapiens)


name: Recruited STAT5 is phosphorylated (Canis familiaris)


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + H(+) + phosphate => 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine = 1-O-(1Z-alkenyl)-2-acetyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine


name: Aquaporins passively transport water out of cells (Mus musculus)


name: GAF binds the GAS promoter elements in the IFNG-regulated genes (Homo sapiens)


name: (S)-lactate(out) + 2 Na(+)(out) = (S)-lactate(in) + 2 Na(+)(in)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Plasmodium falciparum)


name: campesteryl 3-beta-D-glucoside + H2O <=> campesterol + D-glucose


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H(+) + UDP


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate = 1,3-di-(9Z)-hexadecenoylglycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: corticosterone + H(+) + NADPH <=> 5beta-dihydrocorticosterone + NADP(+)


name: L-lysine + NAD(+) = Delta(1)-piperideine-2-carboxylate + H(+) + NADH + NH4(+)


name: RHOA binds effectors at the ER membrane (Canis familiaris)


name: Alkalization of the phagosomal lumen by NOX2 (Homo sapiens)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Sus scrofa)


name: LONP1 binds mitochondrial matrix proteins (Sus scrofa)


name: Formation of the Flap Intermediate (Canis familiaris)


name: a ubiquinone + 2 e(-) + 2 H(+) => a ubiquinol


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Caenorhabditis elegans)


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Rattus norvegicus)


name: 4-O-demethylbarbatate + 6 CO2 + 8 CoA + H2O + 2 S-adenosyl-L-homocysteine => 2 acetyl-CoA + 3 H(+) + 6 malonyl-CoA + 2 S-adenosyl-L-methionine


name: LIG1 and POLB dissociate from repaired dsDNA (Homo sapiens)


name: a ganglioside GM1 + H2O <=> a ganglioside GA1 + N-acetylneuraminate


name: structural constituent of chitin-based larval cuticle


name: transferase activity, transferring nitrogenous groups


name: BACH1:FBXL17 binds SCF(SKP2) complex (Homo sapiens)


name: Activated MET recruits GRB2-1:SOS1 (Sus scrofa)


name: (S)-N-acetyl-1-phenylethylamine + H2O => (S)-1-phenylethylamine + acetate


name: 3 2,3-dihydroxybenzoyl-5'-AMP + 3 L-seryl-5'-AMP = 6 AMP + enterobactin + 7 H(+)


name: WHSC1 binds DNA DSBs (Saccharomyces cerevisiae)


name: cAMP degradation by Phosphodiesterases (Dictyostelium discoideum)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Caenorhabditis elegans)


name: chenodeoxycholate + glycine <=> glycochenodeoxycholate + H2O


name: Caspase-mediated cleavage of gelsolin (Danio rerio)


name: GMP + H2O <=> D-ribose 5-phosphate + guanine


name: SUMOylation of NR1H4 with SUMO1 (Gallus gallus)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] = 1,4-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glycerol 2-phosphate + H2O <=> glycerol + phosphate


name: Activated FGFR2 phosphorylates FRS3 (Mus musculus)


name: Phosphorylation of APS (Xenopus tropicalis)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Homo sapiens)


name: aldehydo-N-acetyl-D-mannosamine + H2O + phosphoenolpyruvate <=> N-acetylneuraminate + phosphate


name: H(+) + N-acetyl-S-(2-succino)-L-cysteine + NADH + O2 <=> H2O + N-acetyl-L-cysteine + NAD(+) + oxaloacetate


name: SGT1:HSP90 binds inactive NLRP3 (Bos taurus)


name: RHOV binds GTP (Drosophila melanogaster)


name: L-phenylalanine(out) + L-serine(in) => L-phenylalanine(in) + L-serine(out)


name: 2'-deoxyinosine + phosphate <=> 2-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine


name: FAHD1 dimer hydrolyses OA to PYR (Sus scrofa)


name: ADP + H(+) + phosphate + taurine(in) => ATP + H2O + taurine(out)


name: RHOA binds effectors at the plasma membrane (Xenopus tropicalis)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho]-glycerol + CoA


name: "Transferring groups other than amino-acyl groups"


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Sus scrofa)


name: Activation of Ca impermeable AMPA receptors (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + L-tyrosyl-[protein] <=> adenosine 3',5'-bisphosphate + H(+) + O-sulfo-L-tyrosine-[protein]


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Schizosaccharomyces pombe)


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Sus scrofa)


name: Arachidonic acid  is converted to 12-oxoETE by ALOX12 (Canis familiaris)


name: IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Gallus gallus)


name: LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Canis familiaris)


name: POLK incorporates dNMP opposite to damaged DNA base (Bos taurus)


name: IL10 dimer binds IL10RA:JAK1 (Mus musculus)


name: CYP51A1 demethylates LNSOL (Mus musculus)


name: an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O => an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + D-galactosamine


name: NANP dephosphorylates Neu5Ac-9-P to Neu5Ac (Gallus gallus)


name: 2-oxo-dATP + H2O <=> 2-oxo-dAMP + diphosphate + H(+)


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Homo sapiens)


name: GALK1 phosphorylates Gal to Gal1P (Mus musculus)


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Mus musculus)


name: (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H2O => 6-methyl-3,7-dioxodecanedioyl-CoA


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Xenopus tropicalis)


name: 3'-phosphoadenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-bisphosphate + H(+) + quercetin 3,4'-bissulfate


name: 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 3 AH2 + CO2 + H(+) => 3 A + FMN + H2O + L-glutamate + O2


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Drosophila melanogaster)


name: Formation of AT-AC C complex (Gallus gallus)


name: AMP + diphosphate + H(+) + L-isoleucine-(+)-7-isojasmonate => (+)-7-isojasmonate + ATP + L-isoleucine


name: all-trans-nonaprenyl diphosphate + H(+) + homogentisate => 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Bos taurus)


name: 26S proteasome degrades TP73 polyubiquitinated by ITCH (Danio rerio)


name: a ganglioside Ac-O-8-GD2(d18:1(4E)) = a ganglioside Ac-O-9-GD2(d18:1(4E))


name: Release of (inferred) platelet cytosolic components (Homo sapiens)


name: CMP-N-beta-acetyl-7-O-acetylneuraminate + CoA => acetyl-CoA + CMP-N-acetyl-beta-neuraminate


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR (Bos taurus)


name: (2E)-butenoyl-CoA + L-lysyl-[protein] => CoA + H(+) + N(6)-(2E)-butenoyl-L-lysyl-[protein]


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Mus musculus)


name: 1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + CoA => (9Z)-octadecenoyl-CoA + 3-octadecanoyl-sn-glycerol


name: cytidine(out) + H(+)(out) => cytidine(in) + H(+)(in)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Plasmodium falciparum)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Xenopus tropicalis)


name: ESR1:ESTG bind the EBAG9 5' region (Homo sapiens)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Drosophila melanogaster)


name: CES1trimer hydrolyses ACEI pro-drugs to ACEIs (Rattus norvegicus)


name: (6S)-5,6,7,8-tetrahydrofolate + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NH4(+)


name: (2E,6E)-farnesyl diphosphate => (+)-germacrene D + diphosphate


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Homo sapiens)


name: Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Rattus norvegicus)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Homo sapiens)


name: (R)-2-benzylsuccinyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (E)-2-benzylidenesuccinyl-CoA + reduced [electron-transfer flavoprotein]


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Gallus gallus)


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Xenopus tropicalis)


name: De novo formation of eIF2:GTP (Drosophila melanogaster)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Schizosaccharomyces pombe)


name: SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3  (Gallus gallus)


name: Activated FGFR4 binds FRS2 (Gallus gallus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (6E,10E)-geranyllinalool + diphosphate


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)


name: 3-maleylpyruvate + H2O = H(+) + maleate + pyruvate


name: O-atom dealkylation of dextromethorphan (Mus musculus)


name: dimethylallyl diphosphate = diphosphate + isoprene


name: (2S-3S)-versiconal hemiacetal <=> H2O + versicolorin B


name: LAIR1 binds collagen (Xenopus tropicalis)


name: (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA = (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O


name: BRD7 binds TP53 and EP300 (Canis familiaris)


name: Release of docked serotonin loaded synaptic vesicle (Mus musculus)


name: (9Z)-octadecenoyl-CoA + H(+) + malonyl-CoA => (11Z)-3-oxoicosenoyl-CoA + CO2 + CoA


name: S-(4-hydroxy-3-methylbutan-2-yl)-L-cysteine => 2-aminoprop-2-enoate + 2-methyl-3-sulfanylbutan-1-ol


name: Binding of TFIIIA To type 1 Promoter (Gallus gallus)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Schizosaccharomyces pombe)


name: 2-oxo-3-sulfanylpropanoate + L-kynurenine <=> H2O + kynurenate + L-cysteine


name: Activated FGFR4 phosphorylates SHC1 (Drosophila melanogaster)


name: H(+) + 2 L-arginine + 3 NADH + 4 O2 = 4 H2O + 2 L-citrulline + 3 NAD(+) + 2 nitric oxide


name: biotin(in) + 2 Na(+)(in) => biotin(out) + 2 Na(+)(out)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Bos taurus)


name: EBP isomerizes ZYMSTNL to LTHSOL (Dictyostelium discoideum)


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Sus scrofa)


name: 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) => eupatolide + H2O


name: CAMKK2 phosphorylates AMPK (Homo sapiens)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Saccharomyces cerevisiae)


name: Release of GNB5:RGS dimers from CCT/TRiC (Sus scrofa)


name: ATP + L-amino acyl-L-seryl-[protein] => (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + ADP + H(+) + phosphate


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Mus musculus)


name: (S)-alpha-terpineol + diphosphate => (2E)-geranyl diphosphate + H2O


name: Association of HMGB1/HMGB2 with chromatin (Bos taurus)


name: 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O <=> 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: keto-D-tagatose 6-phosphate => aldehydo-D-galactose 6-phosphate


name: 5-oxo-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase] = 5-oxo-18-hydroxy-(6E,8Z)-octadecadienoate + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: HCFC1, HCFC2 bind the MLL1:MEN1 complex (Homo sapiens)


name: MRE11 binds cytosolic DNA (Homo sapiens)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Drosophila melanogaster)


name: 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester => H2O + Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine


name: 2,5-diformylfuran + H2O2 => 5-hydroxymethylfurfural + O2


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + ATP + CoA <=> (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoyl-CoA + AMP + diphosphate


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Rattus norvegicus)


name: 24-ethylidenelophenol 4alpha-methyl oxidase activity


name: decanedioyl-CoA + O2 = (2E)-decenedioyl-CoA + H2O2


name: mannose-1-phosphate guanylyltransferase (GDP) activity


name: a very-long-chain (3S)-hydroxyacyl-CoA => a very-long-chain (2E)-enoyl-CoA + H2O


name: 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: TPCN1/2 transport lysosomal Ca2+ to cytosol  (Sus scrofa)


name: ATP + N-acetyl-alpha-D-galactosamine => ADP + H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate


name: H(+)(out) + L-asparagine(in) + Na(+)(in) => H(+)(in) + L-asparagine(out) + Na(+)(out)


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + [thyroglobulin]-3-iodo-L-tyrosine + H2O2 => [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O


name: H(+) + hydroxyacetone phosphate + NADH => NAD(+) + propane-1,2-diol 1-phosphate


name: cholest-5-en-3-one + H(+) + NADH => cholesterol + NAD(+)


name: ATP + butanoate + H(+) + NADPH <=> AMP + butanal + diphosphate + NADP(+)


name: HIF-alpha translocates from cytosol to nucleus (Mus musculus)


name: alizarin + UDP-alpha-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP


name: Dimethyl fumarate modifies Cys191 in GSDMD (Canis familiaris)


name: Association of procollagen type XIX (Drosophila melanogaster)


name: L-idonate + NADP(+) => 5-dehydro-D-gluconate + H(+) + NADPH


name: D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH


name: (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + NADP(+) => 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + NADPH


name: FDPS dimer transfers IPPP to DMAPP (Plasmodium falciparum)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine <=> 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: (2E,6E,10E)-geranylgeraniol + H(+) + 2 NADPH + 2 O2 => (2E,6E,10E)-geranylgeranate + 3 H2O + 2 NADP(+)


name: TBK1 phosphorylates STAT6 at Ser407 (Sus scrofa)


name: Prolysyl oxidase activation (Drosophila melanogaster)


name: cortisol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 18-hydroxycortisol + H2O + 2 oxidized [adrenodoxin]


name: (R)-dihydrolipoamide + NAD(+) => (R)-lipoamide + H(+) + NADH


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Rattus norvegicus)


name: Release of STAT1 dimer from active receptor unit (Danio rerio)


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Rattus norvegicus)


name: a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Xenopus tropicalis)


name: cytidine(32) in tRNA(Ser) + S-adenosyl-L-methionine = H(+) + N(3)-methylcytidine(32) in tRNA(Ser) + S-adenosyl-L-homocysteine


name: ULK1 Translocates to the mitochondria (Xenopus tropicalis)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Mus musculus)


name: S-adenosyl-L-methionine + uridine(341) in tmRNA <=> 5-methyluridine(341) in tmRNA + H(+) + S-adenosyl-L-homocysteine


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] => 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]


name: "(E3-independent) E2 ubiquitin-conjugating enzyme"


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA = an acyl-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + holo-[ACP]


name: Thrombin-activated PARs:G12/13 (active) dissociate (Canis familiaris)


name: L-lysine + pyruvate => (S)-2-amino-6-oxohexanoate + L-alanine


name: oligopeptide transmembrane transporter activity


name: miR-211 represses POU3F2 mRNA translation (Homo sapiens)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Sus scrofa)


name: HRH1 binds HRH1 inverse agonists (Gallus gallus)


name: L-alanine + oxomalonate => aminomalonate + pyruvate


name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Homo sapiens)


name: NUDT16 hydrolyses dIDP to dIMP (Mus musculus)


name: H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin => 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O


name: AKT-phosphorylated FOXO3 translocates to cytosol (Drosophila melanogaster)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Homo sapiens)


name: GNRHR binds GNRHR peptide agonists (Caenorhabditis elegans)


name: L-cystine(in) + Na(+)(in) <=> L-cystine(out) + Na(+)(out)


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Homo sapiens)


name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Rattus norvegicus)


name: RNA Polymerase III Promoter Opening at Type 3 Promoters (Homo sapiens)


name: glutathione disulfide oxidoreductase activity


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Homo sapiens)


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Sus scrofa)


name: Hydrolysis of PIP2 by PLCG (Gallus gallus)


name: (E)-feruloyl-CoA + 16-hydroxyhexadecanoate => 16-feruloyloxyhexadecanoate + CoA


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Danio rerio)


name: BRF1 Complex recruits RNA degradation activities (Xenopus tropicalis)


name: p-S10 CDKN1B translocates to the cytosol (Sus scrofa)


name: (+)-copalyl diphosphate + H2O = diphosphate + phyllocladan-16alpha-ol


name: TRIAP1 binds PRELID1, PRELID3A (Schizosaccharomyces pombe)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR3 (Sus scrofa)


name: AGO1,2:small RNA complexes interact with chromatin (Caenorhabditis elegans)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Sus scrofa)


name: a 2'-deoxyribonucleoside + ATP <=> a 2'-deoxyribonucleoside 5'-phosphate + ADP + H(+)


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Homo sapiens)


name: VD3 translocates from ER membrane to extracellular region (Homo sapiens)


name: 2-methylbutanoyl-CoA + ethanol = CoA + ethyl 2-methylbutanoate


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Xenopus tropicalis)


name: (9Z)-octadecenoate + H2O => 10-hydroxyoctadecanoate


name: p-AMPK:AMP binds the ULK complex (Caenorhabditis elegans)


name: poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends


name: XDH oxidizes xanthine to form urate (Canis familiaris)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Rattus norvegicus)


name: a 2-oxocarboxylate + a quinol + NH4(+) => a D-alpha-amino acid + a quinone + H2O


name: a fatty acid(out) + ATP(in) + CoA(in) + H(+)(out) = a fatty acyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: L-threonyl-[protein] + phosphate => H2O + O-phospho-L-threonyl-[protein]


name: enterobactin + UDP-alpha-D-glucose => monoglucosyl-enterobactin + UDP


name: calciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> calcidiol + H2O + 2 oxidized [adrenodoxin]


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Danio rerio)


name: dTDP-beta-L-evernosamine + H(+) + 2 NADPH + 2 O2 => dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 3 H2O + 2 NADP(+)


name: TCF7L1/TCF7L2/LEF1:CTNNB1 bind the MYC gene (Homo sapiens)


name: D-cysteine + H2O = H(+) + hydrogen sulfide + NH4(+) + pyruvate


name: platelet-activating factor acetyltransferase activity


name: 19-(4-hydroxyphenyl)nonadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] => 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: NaS1 co-transports sulphate and a sodium ion (Rattus norvegicus)


name: ATP + L-valine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate = ADP + dapdiamide A + H(+) + phosphate


name: gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity


name: PTPN11:p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)


name: all-trans-4,4'-diaponeurosporene + FADH2 => all-trans-4,4'-diapo-zeta-carotene + FAD + H(+)


name: eukaryotic elongation factor-2 kinase activator activity


name: 4beta-methylzymosterol-4alpha-carbaldehyde + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4beta-methylzymosterol-4alpha-carboxylate + 2 Fe(III)-[cytochrome b5] + H2O


name: CYP2D6 4-hydroxylates debrisoquine (Sus scrofa)


name: 2,3-dioxopropyl phosphate + 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate => 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + L-aspartate 4-semialdehyde


name: 2-acyl LPS is acylated to PS by LPSAT (Homo sapiens)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-sn-glycerol + phosphate


name: CTP + H(+) + phosphoethanolamine = CDP-ethanolamine + diphosphate


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Drosophila melanogaster)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Drosophila melanogaster)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Canis familiaris)


name: guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose <=> a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: Expression of Plasminogen activator inhibitor 2 (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Dictyostelium discoideum)


name: CMP + 2 H(+) + sn-glycerol 3-phosphate => CDP-glycerol + H2O


name: lipid-linked peptidoglycan transporter activity


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Bos taurus)


name: Benzene is hydroxylated to phenol (Drosophila melanogaster)


name: (3R)-beta-leucine + H2O + NAD(+) => 4-methyl-3-oxopentanoate + H(+) + NADH + NH4(+)


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + L-lysyl(27)-[histone H3] + 2 succinate


name: an N-fatty-acyl-L-alpha-amino acid + H2O <=> a fatty acid + an L-alpha-amino acid


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Plasmodium falciparum)


name: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) => biphenyl-2,3-diol + O2


name: UBA1 adenylates ubiquitin in the nucleoplasm (Plasmodium falciparum)


name: L-seryl-[protein] + NAD(+) => H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-seryl-[protein]


name: dimethylallyl diphosphate + neoechinulin A = diphosphate + variecolorin G


name: (2R)-S-methyl-3-phospho-1-thioglycerate + H2O <=> (2R)-S-methyl-1-thioglycerate + phosphate


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Homo sapiens)


name: promoter-terminator loop anchoring activity


name: SUMOylation of DAXX with SUMO1 (Bos taurus)


name: Formation of ADAR2  homodimer (Mus musculus)


name: Association of procollagen type I (Caenorhabditis elegans)


name: formononetin + O2 + reduced [NADPH--hemoprotein reductase] <=> 2'-hydroxyformononetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 (2E,6E)-farnesyl diphosphate <=> diphosphate + presqualene diphosphate


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Xenopus tropicalis)


name: a ganglioside GT1aalpha (d18:1(4E)) + CMP + H(+) => a ganglioside GD1alpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: 2,6-dihydroxypseudooxynicotine + AH2 => 6-hydroxypseudooxynicotine + A + H2O


name: RAC1:GTP and MSN activate HEP (Drosophila melanogaster)


name: AKT phosphorylates FOXO1A (Mus musculus)


name: ADP + H(+) + phosphate + phosphonate(in) => ATP + H2O + phosphonate(out)


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Canis familiaris)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Bos taurus)


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Bos taurus)


name: (3R,4R)-3,4-dihydroxy-3,4-dihydrobenzoate + pyruvate => chorismate + H2O


name: (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + O2 <=> (5,6,15R)-trihydroxy-(7E,9E,11Z,13E,17Z)-eicosapentaenoate


name: TRiC/CCT binds unfolded G-protein beta subunit (Bos taurus)


name: IMPDH tetramers binds IMPDH inhibitors (Xenopus tropicalis)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Homo sapiens)


name: 2 3',4'-dihydroxyaurone + 2 H2O => 2 2',3,4-trihydroxy-trans-chalcone + 2 H(+) + O2


name: KDM6B binds iron (Schizosaccharomyces pombe)


name: CO2 + formaldehyde + oripavine + succinate => 2-oxoglutarate + O2 + thebaine


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Canis familiaris)


name: 8-hydroxycopalyl diphosphate + H2O <=> diphosphate + sclareol


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Dictyostelium discoideum)


name: Aquaporins passively transport urea out of cells (Homo sapiens)


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + S-adenosyl-L-methionine <=> a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide + H(+) + S-adenosyl-L-homocysteine


name: 3-oxoisoapionate 4-phosphate + H(+) <=> CO2 + L-erythrulose 1-phosphate


name: a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 <=> a (8S,9S)-5-glyceryl-2'-deoxycytidine in DNA + CO2 + glyoxylate


name: B-RAF dissociates from S111/S120 p-SPRY2 (Gallus gallus)


name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Danio rerio)


name: Activated FGFR1 binds SHC1 (Canis familiaris)


name: The anterograde IFT train dissociates (Sus scrofa)


name: Factor D cleaves C3b-bound Factor B (Xenopus tropicalis)


name: (E)-sinapyl alcohol + UDP-alpha-D-glucose => 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol + H(+) + UDP


name: a ribonucleoside 5'-triphosphate + AMP => a ribonucleoside 5'-diphosphate + ADP


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Danio rerio)


name: DCN binds collagen I, II, III, VI fibrils (Bos taurus)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Rattus norvegicus)


name: Abortive HIV-1 Initiation Before Second Transition (Homo sapiens)


name: Loading of PCNA - Sliding Clamp Formation (Drosophila melanogaster)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: ATF2 acetylates histone H2B, H4 (Sus scrofa)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Bos taurus)


name: Kinesin-13 is a dimer (Rattus norvegicus)


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: PRKACA phosphorylates TNNI3 (Mus musculus)


name: betaine aldehyde hydrate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => choline + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: p-PKR dimer localizes to the nucleus (Gallus gallus)


name: (15Z)-tetracosenoate + NH4(+) => (15Z)-tetracosenamide + H2O


name: cGMP dissociates from CNG channels (Rattus norvegicus)


name: (2S)-2-acetolactate + H(+) + NADPH => (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+)


name: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 => CO2 + H(+) + H2O + scopolamine + succinate


name: H(+) + hexan-3-one + NADPH + O2 <=> H2O + NADP(+) + propyl propanoate


name: a ubiquinone + H2O + pyruvate => a ubiquinol + acetate + CO2


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Rattus norvegicus)


name: H2O + L-tryptophan + O2 = H2O2 + indole-3-pyruvate + NH4(+)


name: 15-cis-phytoene + 2 a plastoquinone <=> 9,9',15-tri-cis-zeta-carotene + 2 a plastoquinol


name: 2-dehydro-3-deoxy-D-gluconate + NADP(+) <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH


name: a disubstituted aliphatic (S)-hydroxynitrile = a ketone + hydrogen cyanide


name: [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + O-phospho-L-serine <=> [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + phosphate


name: p75NTR:NgR complex interacts with the axonal inhibitor LINGO1 (Sus scrofa)


name: STAT3,STAT6 bind p-Y-IL4R (Gallus gallus)


name: Beclin-1 complex phosphorylates PtdIns (Canis familiaris)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Caenorhabditis elegans)


name: S1P hydrolyzes SREBP1A,1C,2 (Homo sapiens)


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Dictyostelium discoideum)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Gallus gallus)


name: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) <=> diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Drosophila melanogaster)


name: FKBP1A binds tacrolimus (Caenorhabditis elegans)


name: 2-oxoglutarate(in) + malonate(out) => 2-oxoglutarate(out) + malonate(in)


name: H(+) + pyruvate + sulfite => (2R)-3-sulfolactate


name: HMG CoA => acetoacetic acid + acetyl CoA (Rattus norvegicus)


name: H(+) + N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine => L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine


name: PRMT1 methylates ESRs (Canis familiaris)


name: D-cellopentaose + O2 = D-cellopentaono-1,5-lactone + H2O2


name: α1-antagonists bind ADRA1A,B,D (Homo sapiens)


name: (R)-S-lactoylglutathione = glutathione + methylglyoxal


name: GABA loaded synaptic vesicle Docking and Priming (Bos taurus)


name: H2O + N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine <=> a fatty acid + H(+) + N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Homo sapiens)


name: D-cellobiono-1,5-lactone + H2O => 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)


name: ADP + ADP <=> AMP + ATP [AK2] (Homo sapiens)


name: OPN (osteopontin) degradation by MMP3, MMP7 (Canis familiaris)


name: SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Bos taurus)


name: SUMOylation of NR3C1 (GR) with SUMO1 (Rattus norvegicus)


name: indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP


name: TP53 binds the CASP6 gene (Homo sapiens)


name: Cleavage of uracil by TDG glycosylase (Rattus norvegicus)


name: Phosphorylated MOB1A proteins associate with LATS proteins (Canis familiaris)


name: Disintegration of matrix layer (Homo sapiens)


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Homo sapiens)


name: 26Sproteasome degrades K48polyUb-NIK (Saccharomyces cerevisiae)


name: MeSeH is methylated to Me2Se by MeSeH methyltransferase (Homo sapiens)


name: Formation of Cyclin A:Cdk2 complexes (Mus musculus)


name: ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA (Homo sapiens)


name: 2-oxoglutarate(out) + 3 Na(+)(out) <=> 2-oxoglutarate(in) + 3 Na(+)(in)


name: (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+) => a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA


name: 8-hydroxycopalyl diphosphate + H2O => diphosphate + sclareol


name: HEXB cleaves the terminal GalNAc from small HA fragments (Dictyostelium discoideum)


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)


name: 2-oxobutanoate + H(+) + pyruvate <=> (S)-2-ethyl-2-hydroxy-3-oxobutanoate + CO2


name: 2 diphosphate + NAD(+) + squalene => 2 (2E,6E)-farnesyl diphosphate + H(+) + NADH


name: trinitrophenol dihydride denitratase activity


name: p-Y705,S727-STAT3 dimerizes (Bos taurus)


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Bos taurus)


name: AKT phosphorylates MKRN1 (Drosophila melanogaster)


name: 7-methylxanthine + H(+) + NADPH + O2 => formaldehyde + H2O + NADP(+) + xanthine


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Xenopus tropicalis)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: Molybdenum ion transfer onto molybdopterin (Bos taurus)


name: [PQQ precursor protein] + S-adenosyl-L-methionine = 5'-deoxyadenosine + E-Y cross-linked-[PQQ precursor protein] + H(+) + L-methionine


name: 4-methylpentan-1-ol + NADP(+) = 4-methylpentanal + H(+) + NADPH


name: Formation of soluble VTN:C5b-C9  (Mus musculus)


name: Interaction of Tie2 and Grb2 (Xenopus tropicalis)


name: Interleukin-12 binds Interleukin-12 receptor (Bos taurus)


name: The receptor:G-protein complex releases GDP (Xenopus tropicalis)


name: (2Z,6E)-farnesyl diphosphate + 9 isopentenyl diphosphate <=> di-trans,nona-cis-dodecaprenyl diphosphate + 9 diphosphate


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Mus musculus)


name: PGH2 is reduced to PGF2a by AKR1C3 (Sus scrofa)


name: KDM6B binds iron (Caenorhabditis elegans)


name: FAHD1 dimer hydrolyses OA to PYR (Canis familiaris)


name: [(1->2)-beta-D-glucosyl](n)(in) + ATP + H2O <=> [(1->2)-beta-D-glucosyl](n)(out) + ADP + H(+) + phosphate


name: H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline => 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Detection of damage during initiation of DNA synthesis in S-phase (Gallus gallus)


name: acetyl-CoA + noradrenaline => CoA + H(+) + N-acetylnoradrenaline


name: an N-acylsphing-4-enine 1-phosphate + H2O => an N-acylsphing-4-enine + phosphate


name: a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Homo sapiens)


name: Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + H(+) + H2O = Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine] + N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine


name: RAB:GTP recruits GBF1 to the Golgi membrane (Plasmodium falciparum)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Danio rerio)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: geranylgeranyl diphosphate + H2O => (S)-(+)-nephthenol + diphosphate


name: RIPK3 is cleaved by CASP8 (Canis familiaris)


name: Aquaporins passively transport urea out of cells (Sus scrofa)


name: 2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] <=> CO2 + H(+) + propanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin]


name: 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Schizosaccharomyces pombe)


name: SMAD2/3:SMAD4 heterotrimer binds SP1 (Drosophila melanogaster)


name: CYP2J2 oxidises ARA (Drosophila melanogaster)


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR (Bos taurus)


name: SUMOylation of NOP58 with SUMO1 (Schizosaccharomyces pombe)


name: 3-oxoglycyrrhetinate + H(+) + NADPH => 3alpha-hydroxyglycyrrhetinate + NADP(+)


name: a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: 3-methylquinoline + A + H2O => 3-methylquinolin-2(1H)-one + AH2


name: 4,5,8-trihydroxycasbene + 2 NAD(+) => 2 H(+) + jolkinol C + 2 NADH


name: RHAG transports CO2 from extracellular region to cytosol (Caenorhabditis elegans)


name: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+) => 1D-myo-inositol 1,4,5-trisphosphate + ATP


name: 4-methylpentanal + 2 H2O + 2 oxidized [adrenodoxin] + pregnenolone => (20R,22R)-20,22-dihydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: AOX1 oxidises PXL to PDXate (Caenorhabditis elegans)


name: [protein]-C-terminal Gly-Gly + ATP + H(+) <=> [protein]-C-terminal Gly-Gly-AMP + diphosphate


name: an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H2O => an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-cysteinylglycine + L-glutamate


name: ERBB2 promotes PTK6 autophosphorylation (Bos taurus)


name: TRPM4,5 transport extracellular Na+ to cytosol (Sus scrofa)


name: 3-oxo-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + CO2 + CoA => (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + H(+) + malonyl-CoA


name: a fatty acyl-[ACP] + L-lysyl-[protein] = H(+) + holo-[ACP] + N(6)-(fatty acyl)-L-lysyl-[protein]


name: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-guanidino-1-deoxy-scyllo-inositol + phosphate


name: SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Mus musculus)


name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Bos taurus)


name: corticotrophin-releasing factor receptor activity


name: FGFRL1 binds SPRED1/2 (Rattus norvegicus)


name: 2-dehydro-3-deoxy-6-phospho-D-galactonate => D-glyceraldehyde 3-phosphate + pyruvate


name: an N-acyl-D-aspartate + H2O => a carboxylate + D-aspartate


name: GRB2-1 binds SOS1 (Drosophila melanogaster)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Saccharomyces cerevisiae)


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-sphinganine-1-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + N-hexadecanoylsphinganine


name: a ganglioside GT1c + CMP-N-acetyl-beta-neuraminate => a ganglioside GQ1c + CMP + H(+)


name: S-methyl-5-thio-D-ribulose 1-phosphate => S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: NOTCH1 gene transcription (Homo sapiens)


name: anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) => 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH


name: sphinganine + tetracosenoyl-CoA <=> an N-tetracosenoylsphinganine + CoA + H(+)


name: H(+)(out) + L-idonate(out) => H(+)(in) + L-idonate(in)


name: CoA + H(+) + N-eicosanoylsphinganine => eicosanoyl-CoA + sphinganine


name: RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Bos taurus)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Rattus norvegicus)


name: demethyllactenocin + S-adenosyl-L-methionine <=> H(+) + lactenocin + S-adenosyl-L-homocysteine


name: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH


name: CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Bos taurus)


name: 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA = 1-butanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + GDP-beta-L-fucose => a neolactoside IV(3)-alpha-NeuNAc,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: CD151 interacts with BP180 and the integrin alpha 6 subunit (Bos taurus)


name: Exocytosis of tertiary granule lumen proteins (Homo sapiens)


name: 2 L-glutamate + 2 oxidized [2Fe-2S]-[ferredoxin] => 2-oxoglutarate + 2 H(+) + L-glutamine + 2 reduced [2Fe-2S]-[ferredoxin]


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside V(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Mus musculus)


name: Small molecule inhibitor binds RIPK1, RIPK3 (Mus musculus)


name: CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D (Bos taurus)


name: NADP(+) + sn-glycerol 1-phosphate <=> dihydroxyacetone phosphate + H(+) + NADPH


name: p-PKR dimer phosphorylates ILF3:ILF2 (Caenorhabditis elegans)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Homo sapiens)


name: H2O + L-valine + NAD(+) = 3-methyl-2-oxobutanoate + H(+) + NADH + NH4(+)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Dictyostelium discoideum)


name: a triacyl-sn-glycerol + H2O = a 1,3-diacyl-sn-glycerol + a fatty acid + H(+)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Bos taurus)


name: 4-hydroxybenzoate + 2 H(+) + NADH + O2 <=> CO2 + H2O + hydroquinone + NAD(+)


name: glyoxylate + L-leucine <=> 4-methyl-2-oxopentanoate + glycine


name: griseofulvin + NADP(+) => dehydrogriseofulvin + H(+) + NADPH


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Mus musculus)


name: Binding of IP3 to IP3 receptor (Homo sapiens)


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Canis familiaris)


name: 2''-O-malonyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide => H2O + N(6)-malonyl-L-lysyl-[protein] + NAD(+)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Homo sapiens)


name: P4 bind PGR (in the HSP90 chaperone complex) (Drosophila melanogaster)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Canis familiaris)


name: ANKH transports PPi from cytosol to extracellular region (Bos taurus)


name: PRMT5 binds WDR77 (Drosophila melanogaster)


name: HNF6-dependent synthesis of HNF1B protein (Homo sapiens)


name: H2O2 + IC-asc-DeltaC9-CoA => IC-asc-C9-CoA + O2


name: dodecanoyl-CoA + glycine <=> CoA + H(+) + N-dodecanoylglycine


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Sus scrofa)


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Danio rerio)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Sus scrofa)


name: PPP5C dephosphorylates TP53BP1 (Saccharomyces cerevisiae)


name: (5Z,8Z)-octadecadienoate + O2 <=> (5S)-hydroperoxy-(6E,8Z)-octadecadienoate


name: D-galactose + ganglioside GM2 (d18:1(4E)/18:0) => ganglioside GM1 (d18:1(4E)/18:0) + H2O


name: choline(out) + n H(+)(in) <=> choline(in) + n H(+)(out)


name: ST6GALNAC2 transfers sialic acid to Core 1 mucins (Bos taurus)


name: Cleavage of C3 by C3 convertases (Gallus gallus)


name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Sus scrofa)


name: H2O + methylamine + 2 oxidized [amicyanin] => formaldehyde + 2 H(+) + NH4(+) + 2 reduced [amicyanin]


name: 4-amino-4-deoxyprephenate + NAD(+) = 3-(4-aminophenyl)pyruvate + CO2 + H(+) + NADH


name: IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Mus musculus)


name: uridine in snRNA => pseudouridine in snRNA


name: TRAIL binds TRAIL receptors (Gallus gallus)


name: histone H3R17 methyltransferase activity


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O => (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: NFE2L2 dependent BCL2L1 expression (Homo sapiens)


name: 3-methyloxindole + NADP(+) => 3-methyleneoxindole + H(+) + NADPH


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Xenopus tropicalis)


name: GOPC promotes translocation of CFTR to lysosomes (Canis familiaris)


name: an N-acylsphing-4-enine + H2O = a fatty acid + sphing-4-enine


name: (4E)-hexenoyl-CoA + NADP(+) => (2E,4E)-hexadienoyl-CoA + H(+) + NADPH


name: D-histidine(in) + H(+)(in) + L-ornithine(out) => D-histidine(out) + H(+)(out) + L-ornithine(in)


name: chlordecone alcohol + NADP(+) <=> chlordecone + H(+) + NADPH


name: B3GALT4 transfers Gal to gangliosides (Bos taurus)


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Caenorhabditis elegans)


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Schizosaccharomyces pombe)


name: S-3-(hexan-1-ol)-L-cysteine => 2-aminoprop-2-enoate + 3-sulfanyl-1-hexanol


name: p-S133 CREB1, MEF2D and SRF  bind the ARC gene (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine = (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: 3 a ubiquinol + protoporphyrin IX => 3 a ubiquinone + protoporphyrinogen IX


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Bos taurus)


name: benzaldehyde + H(+) + NADH => benzyl alcohol + NAD(+)


name: Haptoglobin-related Protein binds Hemoglobin (Rattus norvegicus)


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Gallus gallus)


name: SIRT4 transfers ADPRib to GLUD (Sus scrofa)


name: Activated human JNKs migrate to nucleoplasm (Mus musculus)


name: 3-methylbutanoate + CoA + H(+) => 3-methylbutanoyl-CoA + H2O


name: a quinone + D-glucose <=> a quinol + D-glucono-1,5-lactone


name: [phosphate](n) + UTP = [phosphate](n+1) + UDP


name: Formation of dsRNA structure by looping  (Homo sapiens)


name: UROS transforms HMB to URO3 (Saccharomyces cerevisiae)


name: KAT5 acetylates ATM at DNA DSBs (Sus scrofa)


name: ARL2:GTP:ARL2BP binds SLC25A4 (Sus scrofa)


name: (7Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Canis familiaris)


name: PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Mus musculus)


name: (S)-lactate + oxaloacetate => (S)-malate + pyruvate


name: p-EPHB phosphorylates SDC2 (Caenorhabditis elegans)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Mus musculus)


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 <=> (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2


name: (25S)-Delta7-dafachronate + 4 H2O + 3 NADP(+) => 5alpha-cholest-7-en-3-one + 2 H(+) + 3 NADPH + 3 O2


name: (3R)-3-hydroxy-D-aspartate => glycine + glyoxylate


name: glutarate(out) + xanthurenate(in) => glutarate(in) + xanthurenate(out)


name: 3-oxononanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxynonanoyl-[ACP] + NADP(+)


name: 1-deoxy-D-xylulose 5-phosphate + S-(methylsulfanyl)glutathione => glutathione + S-methyl-1-thio-D-xylulose 5-phosphate


name: D-glyceraldehyde + H2O + NADP(+) => (R)-glycerate + 2 H(+) + NADPH


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Danio rerio)


name: GUCYs converts GTP to cGMP (Dictyostelium discoideum)


name: (2S)-3-sulfolactaldehyde + H(+) + NADH => (2S)-3-sulfopropanediol + NAD(+)


name: UDP-alpha-D-galacturonate(out) + UMP(in) => UDP-alpha-D-galacturonate(in) + UMP(out)


name: 3-oxopropanoate + H(+) => acetaldehyde + CO2


name: ROS oxidize thioredoxin (Schizosaccharomyces pombe)


name: Rnd1 interacts with Plexin-B1:Sema4D (Canis familiaris)


name: (4Z)-2-oxohept-4-enedioate + H2O <=> (4S)-4-hydroxy-2-oxoheptanedioate


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Rattus norvegicus)


name: (2E)-decenedioyl-CoA + H2O <=> (3S)-hydroxydecanedioyl-CoA


name: L-pipecolate + NADP(+) <=> Delta(1)-piperideine-2-carboxylate + H(+) + NADPH


name: Activation of MMP9 intermediate form by MMPs (Gallus gallus)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Rattus norvegicus)


name: NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP (Homo sapiens)


name: AH2 + an aldehyde => A + a primary alcohol


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Canis familiaris)


name: Activated FGFR3 phosphorylates PPTN11 (Drosophila melanogaster)


name: PGLYRP1 binds bacterial peptidoglycan (Sus scrofa)


name: Adenylate cyclase converts ATP into cyclic AMP (Dictyostelium discoideum)


name: UDP-alpha-D-glucose + vancomycin aglycone <=> devancoaminyl-vancomycin + UDP


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Sus scrofa)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Rattus norvegicus)


name: Formation of RAD50:MRE11 complex (Dictyostelium discoideum)


name: Kinesins bind microtubules (Mus musculus)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Schizosaccharomyces pombe)


name: (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + O2 = (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-oxazole-[protein] + H2O2


name: prostaglandin H2 => (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde


name: Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Gallus gallus)


name: Phosphorylation of CBL (EGFR:CBL) (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (E)-anol + acetate + NADP(+) = (E)-coumaryl acetate + NADPH


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+) => (2R)-3-phosphoglycerate + ADP-alpha-D-glucose


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Danio rerio)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Saccharomyces cerevisiae)


name: alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP + H(+) => alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)


name: Gbeta:gamma activation of PLC beta (Sus scrofa)


name: 2-methyl-2-(methylamino)propanoate(out) + chloride(out) + 2 Na(+)(out) <=> 2-methyl-2-(methylamino)propanoate(in) + chloride(in) + 2 Na(+)(in)


name: CDK5 phosphorylates TP53 (Rattus norvegicus)


name: Defective SI does not hydrolyze maltotriose (Homo sapiens)


name: STAMBPL1 is a deubiquitinase (Gallus gallus)


name: Dimerization of p-S446-IRF5 (Rattus norvegicus)


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Canis familiaris)


name: Formation of the Spliceosomal B complex (Canis familiaris)


name: Translocation of PLC-gamma1 to PIP2 (Plasmodium falciparum)


name: 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH + O2 => 9alpha-hydroxy-3-oxochola-1,4-dien-22-oyl-CoA + H2O + NAD(+)


name: acetaldehyde + CO2 + CoA + methanethiol => 3-(methylsulfanyl)acryloyl-CoA + 2 H2O


name: p38 MAPK activation by VEGFR (Danio rerio)


name: Cleavage of the signal peptide of Preproghrelin (Mus musculus)


name: ATP + H2O + L-cystine(out) <=> ADP + H(+) + L-cystine(in) + phosphate


name: L-phenylalanine(in) + L-valine(out) => L-phenylalanine(out) + L-valine(in)


name: TTC19 clears UQCRFS1 fragments from Complex III (Danio rerio)


name: spermine dialdehyde = acrolein + N-(4-aminobutyl)-3-aminopropanal


name: COP9 and TOR1 deneddylate STON2 (Homo sapiens)


name: (3S)-6-acetamido-3-aminohexanoate + CoA + H(+) => (3S)-3,6-diaminohexanoate + acetyl-CoA


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Homo sapiens)


name: Extension of pseudopodia by myosin-X in a PI3K dependent manner (Mus musculus)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 1beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + tetradecamide => NH4(+) + tetradecanoate


name: HHAT G287V doesn't palmitoylate Hh-Np (Homo sapiens)


name: Ubiquitinated CI is degraded by the proteasome complex (Drosophila melanogaster)


name: PPARA binds RXRA (Caenorhabditis elegans)


name: (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O => (3R,6R)-6-hydroxy-3-isopropenylheptanoate + H(+)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Rattus norvegicus)


name: DFF dissociates from importin-alpha:importin-beta (Sus scrofa)


name: USP48 cleaves polyubiquitin (Mus musculus)


name: isopentenyl pyrophosphate transmembrate transporter activity


name: esculetin + S-adenosyl-L-methionine <=> H(+) + isoscopoletin + S-adenosyl-L-homocysteine


name: PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Drosophila melanogaster)


name: Aquaporin-7 passively transports glycerol out of cell (Rattus norvegicus)


name: glycocholate + L-histidine <=> glycine + L-histidocholate


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Schizosaccharomyces pombe)


name: 17beta-hydroxy-5alpha-androstan-3-one + UDP-alpha-D-glucuronate => 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + H(+) + UDP


name: MAP2K2 binds MAPK1 (Schizosaccharomyces pombe)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: PIDD1 associates with CRADD (Drosophila melanogaster)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Mus musculus)


name: (8Z,11Z,14Z)-eicosatrienamide + H2O => (8Z,11Z,14Z)-eicosatrienoate + NH4(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Sus scrofa)


name: Protein 4.1 binds CASK (Xenopus tropicalis)


name: Formation of COPII vesicle (Danio rerio)


name: (S)-reticuline + O2 <=> (S)-scoulerine + H(+) + H2O2


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) = 5,7-dihydroxy-4-methylphthalide + H2O


name: a 5-methyl-2'-deoxycytidine in DNA + ADP + 2 H(+) + phosphate + S-adenosyl-L-homocysteine => a 2'-deoxycytidine in DNA + ATP + H2O + S-adenosyl-L-methionine


name: RDH5 oxidises 11cROL to 11cRAL (Sus scrofa)


name: mitogen-activated protein kinase p38 binding


name: CL-LK binds carbohydrates on target cell surface (Canis familiaris)


name: p-S207 KARS displaces HINT1 (Rattus norvegicus)


name: H2O + L-arginine + O2 = 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+) => 17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase]


name: 1D-myo-inositol 5-phosphate + H2O <=> myo-inositol + phosphate


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: Phosphorylated AKT1S1:mTORC1 binds YWHAB (Drosophila melanogaster)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(36-hydroxyhexatriacontadienoyl)-sphing-4-enine = a diacylglycerol + an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontadienoyl)-sphing-4-enine


name: (2E)-geranyl diphosphate => (Z)-beta-ocimene + diphosphate


name: CO2 + formaldehyde + H(+) + nevadensin + succinate => 2-oxoglutarate + gardenin B + O2


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Dictyostelium discoideum)


name: Sprouty lures CBL away from EGFR (Drosophila melanogaster)


name: nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement (Homo sapiens)


name: E-cadherin degradation by MMP9, KLK7 (Gallus gallus)


name: (R)-carnitine + 2,6-dimethylheptanoyl-CoA => CoA + O-2,6-dimethylheptanoyl-(R)-carnitine


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)


name: PIAS4 SUMOylates PARP1 with SUMO1 (Gallus gallus)


name: estrone + PAPS => estrone 3-sulfate + PAP (Rattus norvegicus)


name: PAK1-3 dimer disassociates (Mus musculus)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Xenopus tropicalis)


name: 2-dehydro-3-deoxy-6-phospho-D-galactonate <=> D-glyceraldehyde 3-phosphate + pyruvate


name: Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)


name: a ganglioside Ac-O-9-GD2(d18:1(4E)) + H(+) + UDP => a ganglioside Ac-O-9-GD3(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: Ubiquitination of phospho-p27/p21 (Xenopus tropicalis)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Canis familiaris)


name: Platelet glycoprotein IV (CD36) binds ligands (Homo sapiens)


name: L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate => H2O + O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit]


name: Active LTK phosphorylates IRS1 (Xenopus tropicalis)


name: Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs (Homo sapiens)


name: PKA phosphorylates MAPKAPK5 (Mus musculus)


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)


name: cyanidin 3-O-rutinoside + UDP-alpha-D-glucose <=> cyanidin 3-O-rutinoside 5-O-beta-D-glucoside + H(+) + UDP


name: (2R,3R)-dihydromyricetin + 2-oxoglutarate + O2 <=> CO2 + H(+) + H2O + myricetin + succinate


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Rattus norvegicus)


name: IkB is ubiquitinated and degraded (Danio rerio)


name: IL6ST is tyrosine phosphorylated (Sus scrofa)


name: D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate


name: USP21 deubiquitinates GATA3,IL33 (Sus scrofa)


name: [phosphate](n) + GTP = [phosphate](n+1) + GDP


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Gallus gallus)


name: HCMV C Nucleocapsid Translocation (Homo sapiens)


name: Recruitment of SYK to p-FCERI gamma subunit (Sus scrofa)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Homo sapiens)


name: (3S)-3-aminobutanoyl-CoA = (2E)-butenoyl-CoA + NH4(+)


name: Self-ubiquitination of RNF41 (Danio rerio)


name: IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Canis familiaris)


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Canis familiaris)


name: S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) <=> S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out)


name: CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate (Sus scrofa)


name: Binding of TFIIIB to TFIIC: Type 2 Promoter Complex (Bos taurus)


name: SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Bos taurus)


name: GP1b-IX-V binds filamin (Rattus norvegicus)


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Rattus norvegicus)


name: FUT2 transfers Fuc to LeA to form LeB (Mus musculus)


name: NGEF exchanges GTP for GDP on RHOA (Homo sapiens)


name: Recruitment of PAK to the membrane by binding active RAC1 (Homo sapiens)


name: 25-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: hydroxymethylphosphonate + O2 <=> formate + 2 H(+) + phosphate


name: mechanosensitive monoatomic cation channel activity


name: dodecanoate + H(+) + holo-[ACP] => dodecanoyl-[ACP] + H2O


name: COQ4 decarboxylates MHDB (Schizosaccharomyces pombe)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ATP + CoA => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + AMP + diphosphate


name: (11Z)-hexadecenoyl-CoA + AH2 + O2 = (10E,12Z)-hexadecadienoyl-CoA + A + 2 H2O


name: TCR binds microbial lipid-based antigen via CD1 (Canis familiaris)


name: an N-octadecanoyl-sphingoid base + CoA + H(+) => a sphingoid base + octadecanoyl-CoA


name: ERK5 translocates to the nucleus (Homo sapiens)


name: chorismate + L-glutamine <=> 4-amino-4-deoxychorismate + L-glutamate


name: a 1,2-diacylglycerol + a fatty acyl-[ACP] => a triacylglycerol + holo-[ACP]


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Xenopus tropicalis)


name: Proteasome degrades ubiquitinated ROBO3.1 (Homo sapiens)


name: ADP + H(+) + L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) => ATP + L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: p-S54,92,203-BRF1 binds 14-3-3 (Mus musculus)


name: 2-O-[(E)-feruloyl]-D-galactarate + CoA => (E)-feruloyl-CoA + galactarate


name: (2E,6E)-farnesol + NAD(+) = (2E,6E)-farnesal + H(+) + NADH


name: CoA-disulfide + H2O = 4'-phosphopantetheinyl-CoA disulfide + adenosine 3',5'-bisphosphate + 2 H(+)


name: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H(+) + 2 H2O


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Drosophila melanogaster)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Sus scrofa)


name: 5-deoxy-D-ribulose 1-phosphate => acetaldehyde + dihydroxyacetone phosphate


name: a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out) => a quinol + 2 Fe(III)-[cytochrome c](out)


name: NOTUM releases Hh-Np:GPC5 from the plasma membrane (Canis familiaris)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Drosophila melanogaster)


name: dTDP-alpha-D-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O


name: AVP(20-28) binds AVPR1A,B (Rattus norvegicus)


name: Tyrosine is hydroxylated to dopa (Rattus norvegicus)


name: H(+) + L-tryptophan <=> CO2 + tryptamine


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Rattus norvegicus)


name: gamma-hexachlorocyclohexane = (3R,4S,5S,6R)-pentachlorocyclohexene + chloride + H(+)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 12-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CEACAM1,3,5,6 bind opa proteins (Homo sapiens)


name: dimethylallyl diphosphate + L-tryptophan = 4-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: NTRK3 dimers trans-autophosphorylate (Gallus gallus)


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Homo sapiens)


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Danio rerio)


name: 2xENPP1 hydrolyzes FAD to FMN (Rattus norvegicus)


name: Cation influx mediated by TRPC3/6/7 (Rattus norvegicus)


name: ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Mus musculus)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Mus musculus)


name: SREBP1A,2 binds the MVK promoter (Homo sapiens)


name: Interaction of Tie2 and Grb7 (Rattus norvegicus)


name: 2 H(+) + siroheme => 12,18-didecarboxysiroheme + 2 CO2


name: Phosphorylated KHDRBS1 translocates to the cytosol (Homo sapiens)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Bos taurus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+) => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose


name: thiamine diphosphate(out) = thiamine diphosphate(in)


name: N-acetyl-alpha-neuraminate(out) + 2 Na(+)(out) = N-acetyl-alpha-neuraminate(in) + 2 Na(+)(in)


name: oxidoreductase activity, acting on the CH-CH group of donors


name: CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: Phosphorylation of CARMA1 by PKC-theta (Bos taurus)


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Caenorhabditis elegans)


name: GALNT3 transfers GalNAc to FGF23 (Bos taurus)


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Xenopus tropicalis)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Canis familiaris)


name: aldosterone hemiacetal + UDP-alpha-D-glucuronate => aldosterone hemiacetal 18-beta-glucuronide + H(+) + UDP


name: an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Danio rerio)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Canis familiaris)


name: oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: Na(+)(out) + uridine(out) => Na(+)(in) + uridine(in)


name: PIAS4 SUMOylates HERC2 with SUMO1 (Bos taurus)


name: (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 => (3R,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Rattus norvegicus)


name: FECH binds Fe2+ to PRIN9 to form heme (Danio rerio)


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Homo sapiens)


name: SUMOylation of TOPORS with SUMO1 (Mus musculus)


name: H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP <=> diphosphate + UDP-N-acetyl-alpha-D-glucosamine


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Drosophila melanogaster)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Homo sapiens)


name: CYCS:APAF1 binds procaspase-9 (Sus scrofa)


name: chloride(out) + dopamine(out) + Na(+)(out) => chloride(in) + dopamine(in) + Na(+)(in)


name: (2R,3S)-homoisocitrate => cis-homoaconitate + H2O


name: CYP19A1 binds Aromatase inhibitors (Xenopus tropicalis)


name: 6-phospho-D-glucono-1,5-lactone + H2O => 6-phospho-D-gluconate + H(+)


name: beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-beta-L-fucose => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: Ligand binds to TLR10 (Drosophila melanogaster)


name: Anti-MET recombinant therapeutic antibodies bind MET (Danio rerio)


name: "Thioether and trialkylsulfonium hydrolases"


name: Activation of Cdc42 by pVav1 (Sus scrofa)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Bos taurus)


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Canis familiaris)


name: kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin (Homo sapiens)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Gallus gallus)


name: 2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> H(+) + hexadecanoate + sn-glycerol 3-phosphocholine


name: ALOX5 oxidises DHA to 7-HDHA (Xenopus tropicalis)


name: Surface deployment of platelet dense granule membrane components (Caenorhabditis elegans)


name: (8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O <=> (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: CFTR transports Cl- from cytosol to extracellular region (Mus musculus)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Rattus norvegicus)


name: SHC1 phosphorylation by phosphorylated EGFR (Mus musculus)


name: daunorubicin + H(+) + NADPH => 13-dihydrodaunorubicin + NADP(+)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine <=> 4-O-([2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: G alpha (q) in G (q):RGS complex is inactivated (Gallus gallus)


name: intracellularly ATP-gated ion channel activity


name: Lactoferrin scavenges iron ions (Sus scrofa)


name: FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4 (Rattus norvegicus)


name: AKT1S1 (PRAS40) binds mTORC1 (Homo sapiens)


name: 2 CoA + NAD(+) => CoA-disulfide + H(+) + NADH


name: 2-all-trans-nonaprenylphenol + H(+) + NADPH + O2 => 3-(all-trans-nonaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: H(+) + NADH + presqualene diphosphate => diphosphate + NAD(+) + squalene


name: L-glutamate(in) + N-acetyl-L-cysteine(out) <=> L-glutamate(out) + N-acetyl-L-cysteine(in)


name: H2O + sn-glycero-3-phosphoethanolamine => ethanolamine + H(+) + sn-glycerol 3-phosphate


name: hydroxymethylphosphonate + O2 => formate + 2 H(+) + phosphate


name: H(+) + hispidin + NADH + O2 = 3-hydroxyhispidin + H2O + NAD(+)


name: p-PKR dimer phosphorylates MKK6 (Danio rerio)


name: 1-O-alkyl-2-acyl-sn-glycerol + CDP-ethanolamine <=> 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: 5alpha-pregnane-3,20-dione + NADP(+) = H(+) + NADPH + progesterone


name: Translesion synthesis across unhooked ICL by POLN (Sus scrofa)


name: 18-hydroxy-(9S,10R)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9S,10R)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: a monocarboxylic acid amide + H2O => a monocarboxylate + NH4(+)


name: carnitine + CO2 + succinate => 2-oxoglutarate + 4-(trimethylamino)butanoate + O2


name: (S)-malate + UDP-N-acetyl-alpha-D-glucosamine => (S)-malyl N-acetyl-alpha-D-glucosaminide + H(+) + UDP


name: (4R)-hydroxysphinganine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoyl-(4R)-hydroxysphinganine


name: Formation of the SCF-FBXL7 complex (Rattus norvegicus)


name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Mus musculus)


name: 2xTPK1:Mg2+ phosphorylates THMN (Danio rerio)


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Mus musculus)


name: Assembly of an Active Transcription Complex (Homo sapiens)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Dictyostelium discoideum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: CDC6 association with ORC(1-6) at replication origins (Homo sapiens)


name: p-Y693-STAT4, p-Y705-STAT3 dissociate from IL23:IL23 receptor (Mus musculus)


name: cholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase]


name: enterobactin + H2O = N-(2,3-dihydroxybenzoyl)-L-serine trimer


name: (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Xenopus tropicalis)


name: BPHL hydrolyses VACV to ACV (Mus musculus)


name: Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: acetate + L-phenylalanine => H2O + N-acetyl-L-phenylalanine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + H(+) + phosphate => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O


name: PKC-delta is activated (Caenorhabditis elegans)


name: arsenite + 3 glutathione + H(+) => arsenic triglutathione + 3 H2O


name: (2E,6E)-farnesyl diphosphate = (+)-amorpha-4,11-diene + diphosphate


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O


name: 2 a thiol + L-cysteinyl-[sulfatase] + O2 => 3-oxo-L-alanyl-[sulfatase] + an organic disulfide + H(+) + H2O + hydrogen sulfide


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Rattus norvegicus)


name: Formation of Cyclin B:Cdc2 complexes (Drosophila melanogaster)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Homo sapiens)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-seryl-[protein] + UDP


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Canis familiaris)


name: all-trans-hexaprenyl diphosphate = diphosphate + macrophomene


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Homo sapiens)


name: H(+) + hydroxyacetone + NADH => (S)-propane-1,2-diol + NAD(+)


name: 2,3-dihexadecanoyl-sn-glycerol + H(+) + hexadecanoate => H2O + trihexadecanoylglycerol


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Drosophila melanogaster)


name: (9Z,12Z,15Z)-octadecatrien-1-ol + 1-hexadecanoylglycerone 3-phosphate <=> 1-O-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate + H(+) + hexadecanoate


name: p-T774-PKN1 binds CDC25C (Schizosaccharomyces pombe)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Rattus norvegicus)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Drosophila melanogaster)


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Rattus norvegicus)


name: Diacylgycerol activates Protein kinase C, alpha type (Schizosaccharomyces pombe)


name: H(+) + L-glutaminyl-tRNA(Gln) + phosphate => 5-phosphooxy-L-glutamyl-tRNA(Gln) + NH4(+)


name: MUS81:EME1,EME2 cleaves D-loop (Rattus norvegicus)


name: Transport of L1 into endosomes (Xenopus tropicalis)


name: a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP] => an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP]


name: 2-oxoglutarate + deoxyamidinoproclavaminate + O2 <=> amidinoproclavaminate + CO2 + succinate


name: FLT3LG dimer:FLT3 binds FLT3 (Canis familiaris)


name: ABCF1 binds EIF2 (Saccharomyces cerevisiae)


name: PHF8 demethylates MeK21-histone H4 (Bos taurus)


name: Follistatin (FST) binds Activin (Bos taurus)


name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 (Mus musculus)


name: [(1->4)-beta-D-glucosyl](n) + phosphate => [(1->4)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: AXL autophosphorylates on Y779 and Y821 (Bos taurus)


name: Activated FGFR1 phosphorylates FRS3 (Canis familiaris)


name: a 14alpha-formyl steroid + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => a 14alpha-hydroxymethyl steroid + O2 + reduced [NADPH--hemoprotein reductase]


name: 3'-phosphoadenylyl sulfate + desulfo-A47934 = A47934 + adenosine 3',5'-bisphosphate + H(+)


name: H2O + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] <=> H(+) + S-disulfanyl-L-cysteinyl-[SoxY protein] + sulfate


name: HP1 alpha binds Histone H3K9(me)3 (Schizosaccharomyces pombe)


name: DKK promotes clathrin-dependent internalization of LRP6 (Rattus norvegicus)


name: HuR binds the CRM1 nuclear export machinery (Bos taurus)


name: Collagen type VIII degradation by MMP1 (Homo sapiens)


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + 2 H2O + NADP(+) => (4S)-4-hydroxy-L-glutamate + H(+) + NADPH


name: Cleavage of lip22 to lip10 (Rattus norvegicus)


name: DHFR dimer binds DHFR inhibitors (Bos taurus)


name: RHOB binds effectors at the plasma membrane (Caenorhabditis elegans)


name: a long-chain fatty acid + n CO2 + (n+1) CoA + 2n NADP(+) => acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH


name: H2O + N(6)-acetyl-L-lysyl-[histone] <=> acetate + L-lysyl-[histone]


name: (2R,3R)-dihydroquercetin + O2 + reduced [NADPH--hemoprotein reductase] <=> (2R,3R)-dihydromyricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ERCC1:XPF cleaves flaps generated by SSA (Canis familiaris)


name: (2E,9Z)-octadecadienoyl-CoA + H2O => (3S)-hydroxy-(9Z-octadecenoyl)-CoA


name: 3-hydroxydocosanoyl-CoA + NADP(+) => 3-oxodocosanoyl-CoA + H(+) + NADPH


name: ABCB1 transports xenobiotics out of the cell (Dictyostelium discoideum)


name: SLC29A1 transports RBV from extracellular region to cytosol (Xenopus tropicalis)


name: NADH + 2 oxidized [2Fe-2S]-[ferredoxin] => H(+) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)


name: SLC24A1 exchanges 4Na+ for Ca2+, K+ (Homo sapiens)


name: an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + H2O <=> 1D-myo-inositol 1-phosphate + an N-acyl-(4R)-4-hydroxysphinganine + H(+)


name: SARS-CoV-2 nsp8 binds to 7SL RNA (Homo sapiens)


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA => a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA


name: Metallochaperone inserts Cu2+ into MT-CO1 (Drosophila melanogaster)


name: TP53 binds the TIGAR gene (Homo sapiens)


name: RHOB translocates to the endosome membrane (Drosophila melanogaster)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Rattus norvegicus)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Rattus norvegicus)


name: Interaction of Tie2 and p85 of PI3K (Sus scrofa)


name: a 1,2-diacyl-sn-glycerol + H(+) + phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O


name: 3-methyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + S-adenosyl-L-methionine => 3,5-dimethyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + H(+) + S-adenosyl-L-homocysteine


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Canis familiaris)


name: a 2'-deoxyribonucleoside + H(+) + triphosphate => a 2'-deoxyribonucleoside 5'-triphosphate + H2O


name: ATP + L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) => ADP + H(+) + L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: p-MAPKAPK3 phosphorylates BMI1 (Gallus gallus)


name: (2S)-heptan-2-amine + H2O + NAD(+) <=> H(+) + heptan-2-one + NADH + NH4(+)


name: Release of noradrenaline  at the synapse (Mus musculus)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)


name: RHOA binds effectors at the plasma membrane (Bos taurus)


name: (2R)-2-amino-4-oxopentanoate + H(+) + NADH + NH4(+) => (2R,4S)-2,4-diaminopentanoate + H2O + NAD(+)


name: PAO:FAD oxidises NASPM to PTCN (Homo sapiens)


name: (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O


name: a carotenoid epsilon-end group => a carotenoid psi-end group


name: (1R,3R)-chrysanthemal + H(+) + NADH => (R,R)-chrysanthemol + NAD(+)


name: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA


name: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) => diphosphate + DNA(n+1)


name: (R)-2-hydroxy-3-methylbutyrate + NADP(+) = 3-methyl-2-oxobutanoate + H(+) + NADPH


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Dictyostelium discoideum)


name: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O => scyllo-inosose


name: ubiquitin-modified protein reader activity


name: ALDH1A1 oxidises GA to DGA (Schizosaccharomyces pombe)


name: A + chrodrimanin F = AH2 + chrodrimanin H


name: glutaryl-CoA + H2O = CoA + glutarate + H(+)


name: 2 caldariellaquinol + n H(+)(in) + O2 => 2 caldariellaquinone + n H(+)(out) + 2 H2O


name: IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Canis familiaris)


name: N-methyl-D-dopa + O2 => (3R)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2


name: 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = (2R)-2-O-(alpha-D-mannosyl)-glycerate + phosphate


name: Activated P2Y purinoceptor 12 binds G-protein Gi (Bos taurus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Dictyostelium discoideum)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Dictyostelium discoideum)


name: SLCO4C1 mediates the transport of digoxin (Homo sapiens)


name: PLC-gamma binds to the active receptor (Sus scrofa)


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Homo sapiens)


name: Recruitment of TRAF6/TRAF2 to IPS-1 (Homo sapiens)


name: Phosphopantetheine conjugation of the ACP domain of FAS (Canis familiaris)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Schizosaccharomyces pombe)


name: E2F7 and E2F8 homo- and heterodimers bind the E2F1 gene promoter (Homo sapiens)


name: dihydroxyacetone phosphate => D-glyceraldehyde 3-phosphate


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Gallus gallus)


name: mRNA base-pairing translational repressor activity


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Danio rerio)


name: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate


name: (2E)-dodecenal + H(+) + NADPH => dodecanal + NADP(+)


name: H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine => H(+) + N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl ethanolamine + sn-glycerol 3-phosphate


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Schizosaccharomyces pombe)


name: RHOA:GTP translocates to the ER membrane (Gallus gallus)


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Plasmodium falciparum)


name: FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling (Rattus norvegicus)


name: pppA(2'-5')pG = 3',2'-cGAMP + diphosphate


name: H2O + trihexadecanoylglycerol => dihexadecanoylglycerol + H(+) + hexadecanoate


name: P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Caenorhabditis elegans)


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Homo sapiens)


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate <=> an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)


name: LUM (lumican) binds integrin alpha2beta1 (Homo sapiens)


name: GLI3R translocates to the nucleus (Bos taurus)


name: type I transforming growth factor beta receptor binding


name: PTP1B binds the GH receptor complex (Gallus gallus)


name: L-aspartate(in) + L-tyrosine(out) <=> L-aspartate(out) + L-tyrosine(in)


name: 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase] => 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: alpha-D-Gal-(1->6)-beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + H2O = beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + D-galactose


name: PDPK1 binds PIP3 (Drosophila melanogaster)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Saccharomyces cerevisiae)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+) + octadecanoate


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Caenorhabditis elegans)


name: PDE5A dimer binds PDE5A inhibitors (Mus musculus)


name: 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate <=> H2O + monacolin L carboxylate


name: arsenate + D-glyceraldehyde 3-phosphate + NAD(+) = 1-arsono-3-phospho-D-glycerate + H(+) + NADH


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Rattus norvegicus)


name: FOXM1 stimulates CENPF transcription (Homo sapiens)


name: GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate (Canis familiaris)


name: USP7 deubiquitinates monoubiquitinated PTEN (Gallus gallus)


name: PREDN,PREDL diffuse into hepatic cells (Homo sapiens)


name: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH


name: AMP + diphosphate + H(+) + L-glutamate + NAD(+) => ATP + deamido-NAD(+) + H2O + L-glutamine


name: ABCB1 transports PREDN,PREDL out of kidney cells (Plasmodium falciparum)


name: acetyl-CoA + butan-1-ol => butyl acetate + CoA


name: H2O + L-methionyl-tRNA(Leu) = H(+) + L-methionine + tRNA(Leu)


name: LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) (Homo sapiens)


name: alpha-secretase cleaves the p75NTR extracellular domain (Homo sapiens)


name: Dissociation of the Gi alpha:G olf complex (Canis familiaris)


name: AKAP5 recruits PKC to ROBO2 (Homo sapiens)


name: indole-3-ethanol + NAD(+) <=> H(+) + indole-3-acetaldehyde + NADH


name: RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex (Homo sapiens)


name: CBL-mediated ubiquitination of CIN85 (Canis familiaris)


name: K63polyUb-IRAK1 dissociates (Homo sapiens)


name: 2-oxoglutarate(in) + prostaglandin F2alpha(out) = 2-oxoglutarate(out) + prostaglandin F2alpha(in)


name: EP2 and EP4 receptors can bind PGE2 (Homo sapiens)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Drosophila melanogaster)


name: Phosphorylated PER binds to CLK (Drosophila melanogaster)


name: TTR:RBP:atROL binds to STRA6 receptor (Xenopus tropicalis)


name: mannitol 2-dehydrogenase (NADP+) activity


name: USP13 and OTUD3 deubiquitinate PTEN (Homo sapiens)


name: 7,8-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => 8-hydroxy-7-methoxyflavone + S-adenosyl-L-methionine


name: CYPs hydroxylate DHA to 14(R)-HDHA (Mus musculus)


name: TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Homo sapiens)


name: demethylphylloquinone + H(+) + NADPH => demethylphylloquinol + NADP(+)


name: TRiC/CCT binds unfolded G-protein beta subunit (Schizosaccharomyces pombe)


name: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O = D-ribose 2,5-bisphosphate + H(+)


name: 1,4-dihydroxy-2-naphthoate + all-trans-heptaprenyl diphosphate + H(+) = 2-demethylmenaquinol-7 + CO2 + diphosphate


name: L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Xenopus tropicalis)


name: Hh-Npp binds CDON and PTCH (Mus musculus)


name: CRABP1 binds atRA (Caenorhabditis elegans)


name: CoA + H(+) + N-acetyl-L-glutamate 5-semialdehyde => acetyl-CoA + L-glutamate 5-semialdehyde


name: POLD,POLE complete replication of damaged DNA after TLS (Homo sapiens)


name: SGTA binds mislocalized membrane protein (Mus musculus)


name: Acetylated RUNX3 binds to BRD2 (Drosophila melanogaster)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Xenopus tropicalis)


name: Inactive G alpha (z) reassociates with G beta:gamma (Canis familiaris)


name: SEMA3E binds to PLXND1 (Canis familiaris)


name: TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Rattus norvegicus)


name: NFE2L2-dependent TALDO1 gene expression (Homo sapiens)


name: SLC4A4 cotransports Na+ with 3HCO3- (Mus musculus)


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Canis familiaris)


name: peonidin + UDP-alpha-D-glucose => peonidin 3-O-beta-D-glucoside + UDP


name: (5'S,6'S)-C-glycyluridine + acetaldehyde => L-threonine + uridine-5'-aldehyde


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Gallus gallus)


name: an N-methylornithine lipid + S-adenosyl-L-methionine = an N,N-dimethylornithine lipid + H(+) + S-adenosyl-L-homocysteine


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Rattus norvegicus)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: loading of Serotonin in synaptic vesicles (Mus musculus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Rattus norvegicus)


name: activated MEK2 phosphorylates ERK2 (Gallus gallus)


name: 11-hydroxysugiol + O2 + reduced [NADPH--hemoprotein reductase] => 11,20-dihydroxysugiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of translation initiation complexes containing mRNA that does not circularize (Canis familiaris)


name: Digestion of branched starch (amylopectin) by extracellular amylase (Xenopus tropicalis)


name: [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase


name: Activated FGFR1 phosphorylates SHC1 (Danio rerio)


name: MRN complex binds CDK2 and RBBP8 (Rattus norvegicus)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Schizosaccharomyces pombe)