name: IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Homo sapiens)


name: UVSSA:USP7 deubiquitinates ERCC6 (Canis familiaris)


name: 2-oxoadipate + CO2 + NADH => (2R,3S)-homoisocitrate + NAD(+)


name: Exocytosis of ficolin-rich granule lumen proteins (Mus musculus)


name: Interaction of NCAM1 with Neurocan (Homo sapiens)


name: (-)-cyclopeptine + 2-oxoglutarate + O2 <=> (Z)-dehydrocyclopeptine + CO2 + H2O + succinate


name: 11a-hydroxy-oxytetracycline + H2O + NADP(+) => H(+) + NADPH + O2 + oxytetracycline


name: (2E,6E,10E)-geranylgeraniol + GTP = (2E,6E,10E)-geranylgeranyl phosphate + GDP + H(+)


name: RAB1:GTP recruits GBF1 to the ERGIC (Dictyostelium discoideum)


name: H2O + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2) = beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: BCMO1:Fe2+ cleaves betaC to atRAL (Caenorhabditis elegans)


name: XIAP dissociates from ub-TLE (Gallus gallus)


name: Caspase mediated cleavage of HIP-55 (Homo sapiens)


name: GMPS dimer transforms 6TXMP to 6TGMP (Caenorhabditis elegans)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Bos taurus)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Bos taurus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)


name: very-long-chain enoyl-CoA reductase activity


name: (2E)-octenoyl-CoA + FADH2 => FAD + H(+) + octanoyl-CoA


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Plasmodium falciparum)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Rattus norvegicus)


name: SETD8 monomethylates histone H4 (Rattus norvegicus)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Dictyostelium discoideum)


name: Receptor CCR10 binds CCL27 and 28 ligands (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoyl-CoA + AH2 + O2 <=> (9Z,12Z,15Z)-octadecatrienoyl-CoA + A + 2 H2O


name: 2-oxoglutarate + hexadecanoyl-CoA + O2 <=> 2-hydroxyhexadecanoyl-CoA + CO2 + succinate


name: 11-cis-retinyl hexadecanoate + CoA => 11-cis-retinol + hexadecanoyl-CoA


name: N(2)-(1-hydroxy-2-oxoethyl)-GDP => GDP + glyoxal


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Xenopus tropicalis)


name: ABCA5 transports CHOL from lysosomal lumen to cytosol (Dictyostelium discoideum)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Drosophila melanogaster)


name: RUNX1 binds to TNFRSF18 (GITR) gene promoter and intron 1 (Homo sapiens)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Canis familiaris)


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Mus musculus)


name: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate


name: H(+) + UDP-alpha-D-glucuronate = CO2 + UDP-alpha-D-xylose


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+) => 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O


name: (+)-cubenene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 4-O-demethylbarbatate + S-adenosyl-L-methionine = proatranorin I + S-adenosyl-L-homocysteine


name: (9Z)-octadecenoate + NH4(+) => (9Z)-octadecenamide + H2O


name: Phosphorylation of MEF2 proteins by p38 (Drosophila melanogaster)


name: D-apiitol + NAD(+) <=> aldehydo-D-apiose + H(+) + NADH


name: (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+) => (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH


name: 1-hexadecanoyl-2-(5Z,8Z,11Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (5Z,8Z,11Z)-eicosatrienoate


name: GST trimers transfer GS from GSH to luminal substrates (Drosophila melanogaster)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Dictyostelium discoideum)


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Schizosaccharomyces pombe)


name: RHOD:GTP recruits DAIPH2-3 to endosomes (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphate(in) <=> a 1,2-diacyl-sn-glycero-3-phosphate(out)


name: 6alpha-hydroxyteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxoteasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: a ganglioside GD3 + H2O <=> a ganglioside GM3 + N-acetylneuraminate


name: Activated FGFR2 phosphorylates FRS3 (Homo sapiens)


name: Lysosomal degradation of gap junction plaques (Drosophila melanogaster)


name: 3-oxo-5,6-didehydrosuberyl-CoA + 2 H(+) + NADPH => 2-oxepin-2(3H)-ylideneacetyl-CoA + 2 H2O + NADP(+)


name: N(omega)-methyl-L-arginine + pyruvate = 5-(3-methylguanidino)-2-oxopentanoate + L-alanine


name: 3'-dehydromaltose + H2O => 3-dehydro-D-glucose + D-glucose


name: FMN-N(5)-peroxide + thymine = (Z)-2-methylureidoacrylate + FMN-N(5)-oxide + 2 H(+)


name: glycine + N-carbamoyl-2-oxoglycine => (S)-2-ureidoglycine + glyoxylate


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Caenorhabditis elegans)


name: L-histidyl-[protein] + NAD(+) <=> H(+) + N(tele)-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Rattus norvegicus)


name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) => 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH


name: RHOF GAPs stimulate RHOF GTPase activity (Gallus gallus)


name: 1-(11Z-eicosenoyl)-glycerol + H2O <=> (11Z)-eicosenoate + glycerol + H(+)


name: DHTKD1 dimer decarboxylates 2-OA (Canis familiaris)


name: scopoletin + UDP-alpha-D-glucose <=> H(+) + scopolin + UDP


name: Co(I)-[methylated-thiol-specific corrinoid protein] + H(+) + methyl-coenzyme M => coenzyme M + methyl-Co(III)-[methylated-thiol-specific corrinoid protein]


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Homo sapiens)


name: A + H2O + thymine <=> 5-methylbarbiturate + AH2 + H(+)


name: Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Rattus norvegicus)


name: PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Schizosaccharomyces pombe)


name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene (Homo sapiens)


name: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) <=> (S)-allantoin + CO2


name: propanoyl-CoA + tetradecanoyl-CoA = 3-oxo-2-methylhexadecanoyl-CoA + CoA


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] => 16alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Xenopus tropicalis)


name: Initial activation of proMMP13 by plasmin and trypsin (Caenorhabditis elegans)


name: 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + H2O + O2 <=> H2O2 + NH4(+) + pre-mycofactocin


name: anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity


name: AFG3L2 degrades mitochondrial matrix proteins (Bos taurus)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Xenopus tropicalis)


name: MT3 exchanges zinc for copper (Gallus gallus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 => (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O


name: (1'S,5'S)-5'-hydroxyaverantin + NAD(+) = (S)-5'-oxoaverantin + H(+) + NADH


name: 3-amino-4-hydroxybenzoate + ATP + H(+) + nitrite <=> 3-diazo-4-hydroxybenzoate + AMP + diphosphate + H2O


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Homo sapiens)


name: "rRNA small subunit pseudouridine methyltransferase Nep1"


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Xenopus tropicalis)


name: N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Mus musculus)


name: (1E,2S)-2-methylbutanal oxime = (1Z,2S)-2-methylbutanal oxime


name: (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2 <=> (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate


name: ABC-type doxorubicin transporter activity


name: Autophosphorylation of PTK2 at Y397 (Sus scrofa)


name: GNRHR binds GNRHR peptide agonists (Sus scrofa)


name: SLC45A3 transports Glc from extracellular region to cytosol (Canis familiaris)


name: ASIC trimers:H+ transport extracellular Na+ to cytosol (Xenopus tropicalis)


name: CO2 + formaldehyde + morphine + succinate => 2-oxoglutarate + codeine + O2


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Dictyostelium discoideum)


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Danio rerio)


name: ADP + D-galactose(in) + H(+) + phosphate => ATP + D-galactose(out) + H2O


name: (2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate <=> (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate


name: IL3RB is phosphorylated on Ser-585 (Rattus norvegicus)


name: ganoderate TR + O2 + reduced [NADPH--hemoprotein reductase] => ganoderate Jc + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Mus musculus)


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 16(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Sus scrofa)


name: [sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Homo sapiens)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate


name: (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + NADP(+) => (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H(+) + NADPH


name: benzoyl-CoA + 2 H(+) + 3 malonyl-CoA <=> 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA


name: IL34 dimer:SDC1 binds CSF1R (Bos taurus)


name: CDK5 phosphorylates TP53 (Xenopus tropicalis)


name: PDE3A inhibitors bind PDE3A (Caenorhabditis elegans)


name: H(+) + NADH + S-formylmycothiol => NAD(+) + S-(hydroxymethyl)mycothiol


name: a 27-hydroxysterol + UDP-alpha-D-glucose => a sterol 27-beta-D-glucoside + H(+) + UDP


name: organophosphate ester transmembrane transporter activity


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin = 2-hydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Drosophila melanogaster)


name: PIAS1 SUMOylates DDX5 with SUMO2 (Gallus gallus)


name: EGFR autophosphorylation (Gallus gallus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate


name: 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine => 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Nucleotide exchange on RAB1 (Gallus gallus)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Saccharomyces cerevisiae)


name: (2E,10E)-dode-2,10-dicenoyl-CoA + H2O + oxaloacetate <=> (4E,11E)-2-hydroxytrideca-4,11-dien-1,2,3-tricarboxylate + CoA + H(+)


name: calcitriol + H2O + 2 oxidized [adrenodoxin] => calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Gallus gallus)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Mus musculus)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Homo sapiens)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Caenorhabditis elegans)


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Caenorhabditis elegans)


name: 2-nitroimidazole + H2O = 1,3-dihydro-2H-imidazol-2-one + H(+) + nitrite


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) <=> 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Caenorhabditis elegans)


name: kaempferol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + quercetin


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Homo sapiens)


name: RNF41 ubiquitinates activated ERBB3 (Rattus norvegicus)


name: SDC2 multimerises (Drosophila melanogaster)


name: ATPase synthesizes ATP (Drosophila melanogaster)


name: SMURF2 monoubiquitinates SMAD3 (Mus musculus)


name: SUMOylation of NR1H4 with SUMO1 (Danio rerio)


name: p-STAT1:p-STAT4 translocates to the nucleus (Canis familiaris)


name: RHOC GAPs stimulate RHOC GTPase activity (Homo sapiens)


name: Degradation of ubiquitinated SMAD3 (Homo sapiens)


name: B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda (Mus musculus)


name: Active G alpha (z) binds RGS proteins (Sus scrofa)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate <=> (-)-(E)-beta-caryophyllene + diphosphate


name: p38 MAPK activation by VEGFR (Gallus gallus)


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Drosophila melanogaster)


name: ARHGAP35 binds RASA1 (Xenopus tropicalis)


name: (R)-pantoate + NAD(+) <=> 2-dehydropantoate + H(+) + NADH


name: ADP + H(+) + nitrate(in) + phosphate => ATP + H2O + nitrate(out)


name: 4-nitrocatechol + NADPH + O2 => 2-hydroxy-1,4-benzoquinone + H2O + NADP(+) + nitrite


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Canis familiaris)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O => (14S,15S)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: ADP + ATP + H(+) <=> P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate


name: (R)-2-hydroxyglutarate + FAD + H(+) <=> 2-oxoglutarate + FADH2


name: Parkin transfers Ub to misfolded proteins (Homo sapiens)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Saccharomyces cerevisiae)


name: 8-methylquinoline + A + H2O <=> 8-methylquinolin-2(1H)-one + AH2


name: 19-hydroxy-9alpha,11alpha-methylene thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9alpha,11alpha-methylene thromboxane A2 + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-decanoylglycerol + H2O => decanoate + glycerol + H(+)


name: (R)-3-hydroxy-(13Z)-eicosenoyl-CoA => (2E,13Z)-eicosadienoyl-CoA + H2O


name: Phosphorylated MAPKs translocate into the nucleus (Bos taurus)


name: androst-5-en-3beta,17beta-diol + NAD(+) <=> 3beta-hydroxyandrost-5-en-17-one + H(+) + NADH


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Caenorhabditis elegans)


name: 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate


name: H2O + O(6)-methyl-dGTP = diphosphate + H(+) + O(6)-methyl-dGMP


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ATP + H2O <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ADP + H(+) + phosphate


name: Translocation of PDK1 to Plasma membrane (Homo sapiens)


name: p-Y705-STAT3 dimerizes (Rattus norvegicus)


name: HLCS biotinylates PC:Mn2+ (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Danio rerio)


name: TGFBR2 recruits TGFBR1 (Rattus norvegicus)


name: KDM5A-D demethylate Me3K5-histone H3 (Sus scrofa)


name: L-aspartate(in) + L-valine(out) <=> L-aspartate(out) + L-valine(in)


name: NSF and SNAPs bind cis-SNARE complex (Danio rerio)


name: KPNA2 translocates NBN to the nucleus (Rattus norvegicus)


name: an acyl-CoA + sn-glycerol 3-phosphocholine => a monoacyl-sn-glycero-3-phosphocholine + CoA


name: beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-threonyl-[protein] => H2O + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein]


name: H(+) + NADH + O2 + theobromine <=> 7-methylxanthine + formaldehyde + H2O + NAD(+)


name: Activation of proMMP8 (Xenopus tropicalis)


name: ATP + H2O + pheophorbide a(in) = ADP + H(+) + pheophorbide a(out) + phosphate


name: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Danio rerio)


name: 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O => 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR (Mus musculus)


name: 2 H(+) + precorrin-8X + S-adenosyl-L-homocysteine => precorrin-7 + S-adenosyl-L-methionine


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Sus scrofa)


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Xenopus tropicalis)


name: 8-amino-8-demethylriboflavin + S-adenosyl-L-methionine <=> 8-demethyl-8-(methylamino)riboflavin + H(+) + S-adenosyl-L-homocysteine


name: L-cysteinyl-[NO transferase protein] + S-nitroso-L-cysteinyl-[protein] => L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[NO transferase protein]


name: Oxidative damage to the AP site (Mus musculus)


name: ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG (Sus scrofa)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Xenopus tropicalis)


name: NEIL3 cleaves spiroiminodihydantoin (Homo sapiens)


name: Phosphorylation of BIM by JNK (Sus scrofa)


name: SUCLG1/A2 cleaves succinyl-CoA (Canis familiaris)


name: 2-oxoglutarate + a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + O2 = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + CO2 + formaldehyde + succinate


name: Interaction of Plectin with Integrin beta 4 (Canis familiaris)


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Gallus gallus)


name: PIAS3 SUMOylates MITF with SUMO1 (Homo sapiens)


name: GPIb-IX-V binds to vWF:Collagen complex (Gallus gallus)


name: (+)-endo-beta-bergamotene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: Flipping of the N-glycan precursor to inside the ER (Homo sapiens)


name: H2O + S-benzyl-L-cysteine => benzylthiol + NH4(+) + pyruvate


name: L-idonate 5-dehydrogenase (NAD+) activity


name: SPP1 (osteopontin) binds integrin alpha8beta1 (Homo sapiens)


name: TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Xenopus tropicalis)


name: UBXN1 binds BRCA1:BARD1 heterodimer (Homo sapiens)


name: NLK phosphorylates TCF/LEF (Caenorhabditis elegans)


name: 2 H(+) + malonate + NADH => 3-oxopropanoate + H2O + NAD(+)


name: an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H2O => a thymidine in DNA + ADP-D-ribose


name: an acyl-CoA + H(+) + malonyl-CoA => a 3-oxoacyl-CoA + CO2 + CoA


name: Association of GABA B receptor with G protein beta-gamma subunits (Canis familiaris)


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Mus musculus)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine => 4-O-([2-N-acetyl-alpha-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: (R)-pantoate + ATP + beta-alanine <=> (R)-pantothenate + ADP + H(+) + phosphate


name: [HPr protein]-L-serine + ATP = [HPr protein]-O-phospho-L-serine + ADP + H(+)


name: CIDEA:CIDEC binds lipid droplets (Sus scrofa)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Mus musculus)


name: NUP93 recruits the Nup62 complex (Homo sapiens)


name: ATP + H2O + leukotriene B4(in) <=> ADP + H(+) + leukotriene B4(out) + phosphate


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Canis familiaris)


name: CYP79F1 trihomomethionine monooxygenase activity


name: NF1 is degraded by the proteasome (Canis familiaris)


name: botE HC:LC binds SV2A or B and GT1b on the target cell surface (Homo sapiens)


name: H(+) + tigogenin 3-O-beta-D-glucopyranoside + UDP => tigogenin + UDP-alpha-D-glucose


name: ANTXR2-bound pagA(197-794) forms oligomers (Homo sapiens)


name: GMP(in) + NAD(+)(out) <=> GMP(out) + NAD(+)(in)


name: GDP-mannose transmembrane transporter activity


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Xenopus tropicalis)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Mus musculus)


name: H(+) + NADPH + oxalyl-CoA => CoA + glyoxylate + NADP(+)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA


name: Translocation of active Cdc25C to the nucleus (Homo sapiens)


name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (Canis familiaris)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Caenorhabditis elegans)


name: 6-chloro-D-tryptophan + FAD + 2 H2O => chloride + D-tryptophan + FADH2 + O2


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Gallus gallus)


name: Phosphorylated GAB1 recruits PI3K to MET (Canis familiaris)


name: 4 (R)-methylmalonyl-CoA + 12 H(+) + long-chain fatty acyl-[mycocerosate synthase] + 8 NADPH <=> 4 CO2 + 4 CoA + 4 H2O + 8 NADP(+) + tetramethylated-mycocerosoyl-[mycocerosate synthase]


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Schizosaccharomyces pombe)


name: ACSF3 ligates CoA-SH to VLCFA (Rattus norvegicus)


name: SCF:FBXL7 binds AURKA (Canis familiaris)


name: SMURF1/2 ubiquitinates PTCH1 (Homo sapiens)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Mus musculus)


name: beta-alanyl-[peptidyl-carrier protein] + dopamine => beta-alanyl-dopamine + H(+) + holo-[peptidyl-carrier protein]


name: (3S)-hydroxydodecanedioyl-CoA + NAD(+) = 3-oxododecanedioyl-CoA + H(+) + NADH


name: NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)


name: NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)


name: PIAS1 SUMOylates L3MBTL2 with SUMO2 (Mus musculus)


name: 3-acetyl-3-devinylchlorophyllide a + H(+) + NADH => 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + NAD(+)


name: (2E)-decenoyl-[ACP] + glycine + H2O => (3R)-3-[(carboxylmethyl)amino]decanoate + H(+) + holo-[ACP]


name: Non-enzymatic hydrolysis hydrolyses 13(S),14(S)-epoxy-DHA to 7-epi-MaR1 (Homo sapiens)


name: H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu) => L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein]


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate


name: IL35 binds IL6ST:IL6ST receptor (Rattus norvegicus)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Gallus gallus)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Bos taurus)


name: a bacteriochlorophyllide c + H2O + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + a bacteriochlorophyllide e + 2 H(+) + 2 L-methionine


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Drosophila melanogaster)


name: 3,4,5-trihydroxybenzoate + O2 => (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + 2 H(+)


name: H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate => aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Sus scrofa)


name: GP1b-IX-V binds 14-3-3-zeta (Rattus norvegicus)


name: STRA6 transports atROL from extracellular region to cytosol (Sus scrofa)


name: Activation of Rac1 (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate + H2O = 1,8-cineole + diphosphate


name: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate


name: 3-oxoadipate + NADP(+) => H(+) + maleylacetate + NADPH


name: N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Rattus norvegicus)


name: Dimerization of phosphorylated IRF3/IRF7 (Homo sapiens)


name: TRAF6 is K63 poly-ubiquitinated (Mus musculus)


name: chloride(out) + D-alanine(out) + 2 Na(+)(out) = chloride(in) + D-alanine(in) + 2 Na(+)(in)


name: H(+) + L-xylono-1,4-lactone + NADPH => L-xylose + NADP(+)


name: MYO9B inactivates RHOA (Canis familiaris)


name: Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Xenopus tropicalis)


name: 2 A + all-trans-4,4'-diapolycopene-4,4'-dial + 2 H2O <=> 2 AH2 + all-trans-4,4'-diapolycopene-4,4'-dioate + 2 H(+)


name: PPP1CC dephosphorylates PLK1 (Homo sapiens)


name: AVPR1A,2 bind AVPR antagonists (Rattus norvegicus)


name: cholest-4-en-3-one + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] => (25S)-3-oxocholest-4-en-26-oate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: Intermediate 1 binds HP subcomplex to form Intermediate 2 (Bos taurus)


name: genistein + O2 + reduced [NADPH--hemoprotein reductase] <=> 2'-hydroxygenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine


name: Dissociation of LIG3:XRCC1 complex from the BER site (Homo sapiens)


name: SFKs phosphorylate VAV2,3 (Gallus gallus)


name: IKKbeta phosphorylates IkB causing NF-kB to dissociate (Sus scrofa)


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)


name: Phosphorylation of beta-catenin at Ser552 (Homo sapiens)


name: acetyl-CoA + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine <=> CoA + H(+) + UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose


name: TFRC dimer binds 2xholoTF (Rattus norvegicus)


name: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H2O


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Bos taurus)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + AH2 + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + A + 2 H2O


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Bos taurus)


name: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Sus scrofa)


name: (2E)-geranial + H(+) + NADPH + O2 <=> (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate + H2O + NADP(+)


name: PP2A dephosphorylates RAF1 (Mus musculus)


name: (E)-2,3-didehydroadipoyl-CoA + H2O => (3S)-3-hydroxyadipyl-CoA


name: (E)-4-hydroxyphenylacetaldehyde oxime <=> (Z)-(4-hydroxyphenyl)acetaldehyde oxime


name: [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin] => [thioredoxin]-disulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: PTPN3 dephosphorylates EPS15 (Sus scrofa)


name: PEA15 binds MAPK monomers and dimers (Gallus gallus)


name: adenosine + O2 = 5'-dehydroadenosine + H2O2


name: p62 is recruited and forms a complex with TRAF6 (Bos taurus)


name: L mRNA is translated into protein L (Homo sapiens)


name: TBC1D3 associates with RAB5 (Homo sapiens)


name: ADP + H(+) + Mn(2+)(in) + phosphate => ATP + H2O + Mn(2+)(out)


name: Molybdenum ion transfer onto molybdopterin (Sus scrofa)


name: all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + H(+) + UDP => all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate


name: Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 (Homo sapiens)


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Drosophila melanogaster)


name: Deubiquitinated PTEN translocates to the cytosol (Bos taurus)


name: (-)-vetispiradiene + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + solavetivol


name: 3-methyl-6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone + H(+) + S-adenosyl-L-homocysteine => 6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone + S-adenosyl-L-methionine


name: FAHD1 dimer hydrolyses OA to PYR (Drosophila melanogaster)


name: PHLPP dephosphorylates S473 in AKT (Drosophila melanogaster)


name: A + a 3-oxo-5alpha-steroid <=> a 3-oxo-Delta(4)-steroid + AH2


name: (2E,6E)-farnesyl diphosphate + H2O <=> cubebol + diphosphate


name: POLD,POLE binds deISGylated PCNA after TLS (Drosophila melanogaster)


name: keto-L-sorbose + O2 => 5-dehydro-D-fructose + H2O2


name: H(+)(in) + putrescine(in) <=> H(+)(out) + putrescine(out)


name: CR:atREs binds apoE and HSPG (Rattus norvegicus)


name: SRC-1 phosphorylates p-Y397-PTK2 (Bos taurus)


name: Formation of the 43S pre-initiation complex (Danio rerio)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Dictyostelium discoideum)


name: O2 + reduced [NADPH--hemoprotein reductase] + teasterone <=> 7-oxateasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ALOX5 oxidises DHA to 7-HDHA (Canis familiaris)


name: IMPDH tetramers binds IMPDH inhibitors (Schizosaccharomyces pombe)


name: N-atom dealkylation of caffeine (Mus musculus)


name: NEIL1 translocates to the nucleus (Homo sapiens)


name: Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)


name: ATP + docosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] = AMP + diphosphate + docosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: PIAS1 SUMOylates SAFB with SUMO1 (Caenorhabditis elegans)


name: phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP (Xenopus tropicalis)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Gallus gallus)


name: Expression of lymphocyte cytosolic protein 1 (Homo sapiens)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Rattus norvegicus)


name: Activated FGFR4 phosphorylates PPTN11 (Mus musculus)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Schizosaccharomyces pombe)


name: 5-guanidino-2-oxopentanoate + H2O2 + NH4(+) => H2O + L-arginine + O2


name: SYK binds the activated BCR (Homo sapiens)


name: COQ2 ligates all-E-10PrP2 to PHB (Drosophila melanogaster)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Xenopus tropicalis)


name: Melatonin receptors can bind melatonin (Homo sapiens)


name: B4GALTs transfer Gal to the keratan chain (Rattus norvegicus)


name: Defective GCK does not phosphorylate Glc to form G6P (Homo sapiens)


name: NTPDase4 hydrolyzes nucleoside diphosphates (Canis familiaris)


name: factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Mus musculus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 <=> 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + ouabagenin => dihydroouabagenin + 2 Fe(III)-[cytochrome c]


name: NDUF subunits bind to form the IP subcomplex (Bos taurus)


name: 26S proteasome degrades Ub-NFE2L2 (Homo sapiens)


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Schizosaccharomyces pombe)


name: NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity


name: [protein]-C-terminal glycine + NAD(+) = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide


name: NOTCH1 mRNA translation controlled by miRNAs (Homo sapiens)


name: N-hydroxy-L-isoleucine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-isoleucine + oxidized [NADPH--hemoprotein reductase]


name: ERBB4 forms heterodimers with EGFR (Gallus gallus)


name: (2E)-hexadecenedioyl-CoA + H2O => (3R)-hydroxyhexadecanedioyl-CoA


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Xenopus tropicalis)


name: (S,S)-tartrate(in) + sulfate(out) <=> (S,S)-tartrate(out) + sulfate(in)


name: 1,2-dioctanoyl-sn-glycero-3-diphosphate + H2O => 1,2-dioctanoyl-sn-glycero-3-phosphate + H(+) + phosphate


name: a 2'-unsubstituted isoflavone + O2 + reduced [NADPH--hemoprotein reductase] => a 2'-hydroxyisoflavone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Xenopus tropicalis)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA (Dictyostelium discoideum)


name: H(+) + morphinone + NADPH => morphine + NADP(+)


name: a polyvinyl alcohol + 2n Fe(III)-[cytochrome c] = an oxidized polyvinyl alcohol + 2n Fe(II)-[cytochrome c] + 2n H(+)


name: "polyvinyl alcohol dehydrogenase (cytochrome)"


name: carbon dioxide transmembrane transporter activity


name: NFkB complex translocates from the cytosol to the nucleus (Canis familiaris)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Rattus norvegicus)


name: 13-dihydrodaunorubicin + NADP(+) => daunorubicin + H(+) + NADPH


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Saccharomyces cerevisiae)


name: (4E,11E)-2-hydroxytrideca-4,11-dien-1,2,3-tricarboxylate + 2 H(+) => [4-(deca-1,8-diyl)-2,5-dioxo-2,5-dihydro-3-furanyl]acetate + 2 H2O


name: holo-[(phenol)carboxyphthiodiolenone synthase] + icosanoyl-AMP => AMP + H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: Bitter compound binds bitter taste receptor (TAS2R) (Mus musculus)


name: rhamnetin + S-adenosyl-L-methionine = H(+) + rhamnacene + S-adenosyl-L-homocysteine


name: Activated NTRK3 promotes SRC autophosphorylation (Homo sapiens)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Bos taurus)


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Xenopus tropicalis)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Saccharomyces cerevisiae)


name: 7 CO2 + 7 CoA + 2 H2O + holo-[ACP] + noranthrone => 6 H(+) + hexanoyl-[ACP] + 7 malonyl-CoA


name: NAD(+) + pregnenolone = H(+) + NADH + pregn-5-ene-3,20-dione


name: 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + H2O => 2-O-(alpha-D-glucopyranosyl)glycerol + phosphate


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Drosophila melanogaster)


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Rattus norvegicus)


name: D-threo-isocitrate + NADP(+) => (S)-oxalosuccinate + H(+) + NADPH


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Bos taurus)


name: ATP + butanoyl-CoA + hydrogencarbonate <=> (2S)-ethylmalonyl-CoA + ADP + H(+) + phosphate


name: Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII (Homo sapiens)


name: 11-methyldodecanoyl-CoA + H(+) + malonyl-CoA <=> 3-oxoisopentadecanoyl-CoA + CO2 + CoA


name: cimicifugate D + CoA => (2R,3S)-piscidate + (E)-caffeoyl-CoA


name: L-olivosyl-oleandolide + S-adenosyl-L-methionine <=> H(+) + L-oleandrosyl-oleandolide + S-adenosyl-L-homocysteine


name: TP53 family members bind PPP1R13B or TP53BP2 (Homo sapiens)


name: 4-chlorophenylacetate + NH4(+) => 4-chlorophenylacetonitrile + 2 H2O


name: monoatomic ion transmembrane transporter activity


name: Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Canis familiaris)


name: a 2,3-diacyl-sn-glycerol + H2O => a 3-acyl-sn-glycerol + a fatty acid + H(+)


name: (indol-3-yl)acetate + H(+) => CO2 + skatole


name: CTNNBIP1 binds beta-catenin (Sus scrofa)


name: an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose = a mannosylinositol-1-phosphoceramide + GDP + H(+)


name: H2O + L-kynurenine => anthranilate + H(+) + L-alanine


name: 2 Fe(III)-[cytochrome b5] + H2O + L-arginine => 2 Fe(II)-[cytochrome b5] + 2 H(+) + N(omega)-hydroxy-L-arginine


name: H2O + norspermine + O2 = 3-aminopropanal + H2O2 + norspermidine


name: PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release (Mus musculus)


name: Association of Acrosin Heavy and Light Chain (Mus musculus)


name: O-atom dealkylation of dextromethorphan (Rattus norvegicus)


name: PE is converted to PS by PTDSS2 (Bos taurus)


name: EXC4 is converted to EXD4 by GGT (Homo sapiens)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose => an isogloboside iGb3Cer (d18:1(4E)) + H(+) + UDP


name: pre-VLDL translocates from RER membrane to SER lumen (Homo sapiens)


name: TOPORS SUMOylates IKBKE with SUMO1 (Sus scrofa)


name: Association of Emi1 with Cdh1 (Gallus gallus)


name: Internalization of ubiquitinated FLT3 (Sus scrofa)


name: TRAFs bind RANK:RANKL (Rattus norvegicus)


name: Phosphorylation of SHP2 by SFKs (Danio rerio)


name: ATP + D-cystine(out) + H2O <=> ADP + D-cystine(in) + H(+) + phosphate


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Gallus gallus)


name: alcohol dehydrogenase (NAD+) activity, metal ion-independent


name: MEN1 binds MLL2 complex (Canis familiaris)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Mus musculus)


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Canis familiaris)


name: Formation of the cap-binding eIF4F complex (Caenorhabditis elegans)


name: DLAT trimer transfers acetyl to CoA (Xenopus tropicalis)


name: T1R2/T1R3 dimer is a sweet taste receptor (Homo sapiens)


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Homo sapiens)


name: TRIM21 ubiquitinates SQSTM1 (Gallus gallus)


name: N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate (Bos taurus)


name: H(+)(in) + L-ornithine(out) <=> H(+)(out) + L-ornithine(in)


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin] => 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin]


name: a 2-oxocarboxylate + H(+) + NADPH => a (2R)-2-hydroxycarboxylate + NADP(+)


name: 3-oxooctanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxyoctanoyl-[ACP] + NADP(+)


name: H2O + L-serine-phosphoethanolamine => H(+) + L-serine + phosphoethanolamine


name: D-histidine + S-adenosyl-L-methionine => (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: 1-O-alkyl-2-acetyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine => 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: EBF2 binds target gene loci (Homo sapiens)


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Rattus norvegicus)


name: AH2 + L-cysteine + Mo-molybdopterin = A + H2O + L-alanine + thio-Mo-molybdopterin


name: 17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Endorepellin binds KDR (VEGFR2) (Homo sapiens)


name: H2O + IMP => D-ribose 5-phosphate + hypoxanthine


name: amicoumacin A + ATP = ADP + amicoumacin A 2-phosphate + H(+)


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Sus scrofa)


name: MECOM (EVI1) binds the PTEN gene promoter (Homo sapiens)


name: 15-cis-4,4'-diapophytoene + 4 FAD + 4 H(+) = all-trans-4,4'-diapolycopene + 4 FADH2


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Bos taurus)


name: Phosphorylation of PLC-gamma1 (Sus scrofa)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Rattus norvegicus)


name: TAK1 is activated within the TAK1 complex (Sus scrofa)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Mus musculus)


name: HRH2 binds HRH2 antagonists (Canis familiaris)


name: p-PKR dimer phosphorylates TP53 tetramer (Bos taurus)


name: CYP4F3 20-hydroxylates LTB4 (Homo sapiens)


name: Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Sus scrofa)


name: (15Z)-tetracosenoyl-CoA + sphinganine = CoA + H(+) + N-(15Z-tetracosenoyl)-sphinganine


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)


name: HSPA8 dissociates from LAMP2A-bound substrate (Homo sapiens)


name: RAC1,RAC2,RHOG activate PI3K (Caenorhabditis elegans)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Mus musculus)


name: guanosine(18) in tRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: ITPA hydrolyses dITP to dIMP (Sus scrofa)


name: 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys) => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-lysyl-tRNA(Lys)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Caenorhabditis elegans)


name: cholate + L-alanine <=> H2O + L-alanocholate


name: choline(in) + H(+)(in) <=> choline(out) + H(+)(out)


name: VEGFA-165 dimer binds VEGFR2 dimer (Sus scrofa)


name: G protein-coupled glutamate receptor activity


name: 1-acyl LPC is acylated to PC by LPCAT (Plasmodium falciparum)


name: HGD dioxygenates homogentisate (Mus musculus)


name: dammarenediol-II + O2 + reduced [NADPH--hemoprotein reductase] <=> (20S)-protopanaxadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-ribonucleotide in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: a triacylglycerol + CoA => a 1,2-diacylglycerol + a fatty acyl-CoA


name: a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Dentin matrix protein 1 binds integrin alphaVbeta3 (Rattus norvegicus)


name: Translocation of ISGF3 complex to nucleus (Mus musculus)


name: (2S)-2-amino-4-deoxychorismate + L-glutamate => chorismate + L-glutamine


name: N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + H2O => [(1->4)-N-acetyl-beta-D-glucosaminyl](n-2) + N,N'-diacetylchitobiose


name: (2E)-glutaconyl-CoA + H2O => (R)-2-hydroxyglutaryl-CoA


name: CIDEA:CIDEC binds lipid droplets (Mus musculus)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] => acetyl-CoA + N-terminal L-methionyl-L-glutamyl-[protein]


name: 12-methyltridecanoyl-CoA + 2 H(+) + 2 malonyl-CoA => 4-hydroxy-6-(11-methyldodecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)


name: GUCA binds Ca2+ to form GUCA:Ca2+ (Danio rerio)


name: asperaculane E + O2 + reduced [NADPH--hemoprotein reductase] => asperaculane G + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Dictyostelium discoideum)


name: (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H2O => (3R)-hydroxy-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Homo sapiens)


name: SUMOylation of RARA with SUMO2 (Mus musculus)


name: PRMT6 methylates histone H2A arginine-30 (H2AR29) (Xenopus tropicalis)


name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Bos taurus)


name: RUNX1:CBFB binds CREBBP (Drosophila melanogaster)


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Mus musculus)


name: JAK2-activated MAPKs phosphorylate YBX1 (Bos taurus)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)


name: mitochondrial tRNA pseudouridine(27/28) synthase activity


name: FMN + H2O + NAD(+) => FMN-N(5)-oxide + H(+) + NADH


name: 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose + H(+) + UMP => 3-alpha-D-mannopyranosyl-alpha-D-mannopyranose + UDP-alpha-D-xylose


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: a ubiquinone + 2 H(+)(out) + H2O + nitrite => a ubiquinol + 2 H(+)(in) + nitrate


name: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Rattus norvegicus)


name: 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + UDP-alpha-D-glucose <=> 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-seryl-[protein] + H(+) + UDP


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O


name: an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + GDP-alpha-D-mannose <=> GDP + H(+) + mannosylinositol phosphorylphytoceramide


name: delphinidin 3,5-bis-O-beta-D-glucoside + UDP-alpha-D-glucose <=> delphinidin 3,3',5-tri-O-beta-D-glucoside + H(+) + UDP


name: 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: H2O + presqualene diphosphate => diphosphate + hydroxysqualene


name: Receptor CCR6 binds CCL20 ligand (Mus musculus)


name: (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + holo-[ACP] => (9Z)-hexadecenoyl-[ACP] + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)


name: Phosphorylation of EGFR by SRC kinase (Rattus norvegicus)


name: ARFGAPs stimulate ARF GTPase activity (Drosophila melanogaster)


name: PTPN3 binds p-T183,Y185 MAPK12 (Gallus gallus)


name: 5-taurinomethyluridine(34) in tRNA + AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] <=> 5-taurinomethyl-2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]


name: (E)-caffeoyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] => CoA + myricetin 3-O-[(6-O-(E)-caffeoyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Drosophila melanogaster)


name: Enhanced autophagosome formation (Homo sapiens)


name: Interleukin-3 receptor alpha: Interleukin-3 binds IL3RB:JAK2 (Bos taurus)


name: histamine-gated chloride channel activity


name: USP18 deubiquitinates TAK1:TAB1 (Xenopus tropicalis)


name: NOX2 generates superoxide anion from oxygen (Rattus norvegicus)


name: PGG2 is reduced to PGH2 by PTGS1 (Danio rerio)


name: (2E)-decenoate + ATP + holo-[ACP] <=> (2E)-decenoyl-[ACP] + AMP + diphosphate


name: (12Z)-10-hydroxyoctadecenoate + H2O = 10,13-dihydroxyoctadecanoate


name: Fibronectin degradation by CTSG (Gallus gallus)


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Rattus norvegicus)


name: Aquaporin-4 passively transports water out of cell (Drosophila melanogaster)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Bos taurus)


name: 5-methyltetrahydrosarcinapterin + coenzyme M + 2 Na(+)(in) <=> 5,6,7,8-tetrahydrosarcinapterin + methyl-coenzyme M + 2 Na(+)(out)


name: a dolichyl diphosphate + H2O = a dolichyl phosphate + H(+) + phosphate


name: HMGB1 binds LTP (Schizosaccharomyces pombe)


name: p-Y7-CLEC1B dimer:PDPN binds SYK (Sus scrofa)


name: ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 (Bos taurus)


name: TNF-alpha inhibitors bind to soluble TNF trimer (Bos taurus)


name: TSEN complex cleaves the intron from pre-tRNA (Homo sapiens)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Canis familiaris)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Bos taurus)


name: Formation of CSL-NICD coactivator complex (Bos taurus)


name: cortalcerone + H2O => 2-dehydro-D-glucose


name: RNF8 and RNF168 ubiquitinate H2AFX (Homo sapiens)


name: PKR binds activating host RNA (Canis familiaris)


name: NADPH + 2 nitric oxide + 2 O2 => H(+) + NADP(+) + 2 nitrate


name: POM121 and NDC1 bind the Nup93 complex (Drosophila melanogaster)


name: 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NAD(+) => 5alpha-cholest-8-en-3-one + CO2 + NADH


name: TFAM binds to mitochondrial promoters (Xenopus tropicalis)


name: dimethylallyl diphosphate + H2O + yaequinolone E => [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Drosophila melanogaster)


name: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA


name: ATP + beta-alanine + L-lysine <=> ADP + beta-alanyl-L-lysine + H(+) + phosphate


name: (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+)


name: p115-RhoGEF activation of RHOA (Rattus norvegicus)


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-ribose 1-phosphate <=> (2R)-3-phosphoglycerate + alpha-D-ribose 1,5-bisphosphate + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)


name: MITF-M-dependent MET gene expression (Homo sapiens)


name: Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)


name: a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GM1b + CMP + H(+)


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Rattus norvegicus)


name: a polar amino acid(out) + ATP + H2O <=> a polar amino acid(in) + ADP + H(+) + phosphate


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Homo sapiens)


name: Aquaporins passively transport urea into cells (Saccharomyces cerevisiae)


name: PTP-RO interacts with p-c-Kit complex (Sus scrofa)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Rattus norvegicus)


name: abieta-8,11,13-triene + O2 + reduced [NADPH--hemoprotein reductase] <=> ferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (22R,7alpha)-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (22R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: GLB1 hydrolyzes SapB/C:LacCer (Canis familiaris)


name: L-arabinitol + NAD(+) = H(+) + L-xylulose + NADH


name: (1R,2R,3R)-prephytoene diphosphate + H(+) + NADH => all-trans-lycopaoctaene + diphosphate + NAD(+)


name: (2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin + H(+) = 7-O-geranyl-2-O,3-dimethylflaviolin + diphosphate


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Homo sapiens)


name: cortisone + H(+) + NADH => cortisol + NAD(+)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Danio rerio)


name: NT5C3B hydrolyses 7MGP to 7MG (Canis familiaris)


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Mus musculus)


name: H(+)(out) + L-alanyl-L-proline(out) => H(+)(in) + L-alanyl-L-proline(in)


name: Opsins binds G alpha-t (Xenopus tropicalis)


name: 2 H(+) + heme b => Fe(2+) + protoporphyrin IX


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] <=> 2-heptanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl heptanoate + apo--[retinol-binding protein]


name: 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + O2 => CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate


name: delphinidin + UDP-alpha-D-glucose = delphinidin 3-O-beta-D-glucoside + UDP


name: asperaculane E + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> aculene D + CO2 + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Transport (influx) of bile salts and acids by OATP-A (Caenorhabditis elegans)


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Caenorhabditis elegans)


name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)


name: S-ethyl-L-cysteine => 2-aminoprop-2-enoate + ethanethiol


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Homo sapiens)


name: (9Z)-hexadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) <=> (9Z)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Homo sapiens)


name: Activated FGFR3 phosphorylates FRS2 (Bos taurus)


name: ALDH1A1 oxidises GA to DGA (Dictyostelium discoideum)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Caenorhabditis elegans)


name: TPMT transfers methyl group to 6TIMP, forming 6MeTIMP (Danio rerio)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Plasmodium falciparum)


name: SLC22A1 transports Cipro into hepatic cell (Xenopus tropicalis)


name: An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Danio rerio)


name: Co-precorrin-6B + S-adenosyl-L-methionine <=> Co-precorrin-7 + CO2 + S-adenosyl-L-homocysteine


name: dihydroxyacetone phosphate + glycolaldehyde => D-ribulose 1-phosphate


name: H2O + NAD(+) + perillyl aldehyde => 2 H(+) + NADH + perillate


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Caenorhabditis elegans)


name: Condensin II complex binds H4K20me1-containing nucleosomes (Gallus gallus)


name: H2O + L-saccharopine + NADP(+) <=> (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + pentanoate => 1-hexadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O


name: (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H(+) + NADPH <=> (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + NADP(+)


name: CHUK, IKBKB and IKBKG form IKK complex (Homo sapiens)


name: phosphate(out) + sn-glycerol 3-phosphate(in) => phosphate(in) + sn-glycerol 3-phosphate(out)


name: DAAM1 recruits GTP-bound RHOA (Drosophila melanogaster)


name: Duplex miRNA is loaded into Argonaute (Homo sapiens)


name: DHTKD1 dimer decarboxylates 2-OA (Caenorhabditis elegans)


name: H(+) + NADPH + O2 + octan-3-one = H2O + NADP(+) + pentyl propanoate


name: an N-carbamoyl-D-amino acid + 2 H(+) + H2O <=> a D-alpha-amino acid + CO2 + NH4(+)


name: p-T,Y MAPK dimers translocate to nucleus (Rattus norvegicus)


name: RDH10,11 oxidise 11cROL to 11cRAL (Drosophila melanogaster)


name: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA => 7-methyl-3-oxooct-6-enoyl-CoA + acetate


name: a dolichyl D-xylosyl phosphate + L-seryl-[protein] => 3-O-(beta-D-xylosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)


name: 2-oxobutanoate + L-cysteine <=> (2S)-2-aminobutanoate + 2-oxo-3-sulfanylpropanoate


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Bos taurus)


name: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH


name: (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: "[methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]--tetrahydrofolate methyltransferase"


name: FUT1,2 transfer fucose to gangliosides (Sus scrofa)


name: 15-methylhexadecasphinganine + ATP <=> 15-methylhexadecasphinganine 1-phosphate + ADP + H(+)


name: (9Z)-octadecenoyl-CoA + glycine => CoA + H(+) + N-(9Z-octadecenoyl)glycine


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Homo sapiens)


name: 12-methyloctadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4-hydroxy-6-(13-methyl-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + ATP + CoA => 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: 7beta-hydroxycholesterol(in) + ATP + H2O = 7beta-hydroxycholesterol(out) + ADP + H(+) + phosphate


name: 2 5'-deoxyadenosine + a bacteriochlorophyllide f + 2 H(+) + 2 L-methionine => a bacteriochlorophyllide d + H2O + 2 S-adenosyl-L-methionine


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  (Rattus norvegicus)


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose => a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: GADD45A gene expression is stimulated by FOXO3,FOXO4,(FOXO1) (Homo sapiens)


name: a 2-hydroxycarbonyl + H(+) + NADPH => an L-glycol + NADP(+)


name: Surface deployment of platelet dense granule membrane components (Rattus norvegicus)


name: Expression of HNF4A during nephron development (Homo sapiens)


name: ATP2B4 binds to NOS1, inhibiting it (Dictyostelium discoideum)


name: a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Bos taurus)


name: yaequinolone C => [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B


name: 1,3,5-trihydroxybenzene + NADPH => dihydrophloroglucinol + NADP(+)


name: AZD1979 + H2O <=> AZD1979 oxetane hydrolysis product + H(+)


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Canis familiaris)


name: TULP3 is required for GPR161 localization in the cilium (Mus musculus)


name: H2O + oxaloacetate + propanoyl-CoA => (2S,3S)-2-methylcitrate + CoA + H(+)


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)


name: a plastoquinone + an L-alpha-amino acid + H2O => a 2-oxocarboxylate + a plastoquinol + NH4(+)


name: PGH2 is isomerised to PGD2 by HPGDS (Plasmodium falciparum)


name: mangiferin + O2 = 3'-dehydromangiferin + H2O2


name: p-S54-PDE4B hydrolyses cAMP (Homo sapiens)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Gallus gallus)


name: Defective RB1 does not form a complex with SKP2 and FZR1 (Homo sapiens)


name: (20S)-ginsenoside Rc + H2O <=> (20S)-ginsenoside Rd + L-arabinofuranose


name: IL21 receptor STAT phosphorylation (Mus musculus)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) => (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: TRIF:activated TLR3/TLR4 complex recruits RIP1 (Homo sapiens)


name: H(+) + N(2)-succinyl-L-citrulline + phosphate => carbamoyl phosphate + N(2)-succinyl-L-ornithine


name: (2E,6E)-farnesyl diphosphate = beta-cadinene + diphosphate


name: a (2S,3S)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH


name: Activated ATM phosphorylates DCLRE1C (Homo sapiens)


name: DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Mus musculus)


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Danio rerio)


name: 3,3'-diiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) = 3,3'-diiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: Formation of the closed pre-initiation complex (Dictyostelium discoideum)


name: CDP-D-ribose + diphosphate => CTP + D-ribose 5-phosphate + H(+)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate => 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine


name: 2 D-glyceraldehyde 3-phosphate <=> 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + 2 H2O + phosphate


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Canis familiaris)


name: CDO binds promyogenic cadherins (Mus musculus)


name: baicalein + UDP-alpha-D-glucuronate = baicalin + UDP


name: cis-4-hydroxycyclohexane-1-carboxylate + NAD(+) <=> 4-oxocyclohexane-1-carboxylate + H(+) + NADH


name: Phosphorylation of EGFR by SRC kinase (Homo sapiens)


name: PHGDH tetramer dehydrogenates 3PG (Mus musculus)


name: ATP + H2O + voriconazole(in) <=> ADP + H(+) + phosphate + voriconazole(out)


name: CD22 binds itself to form homo-oligomers (Canis familiaris)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Xenopus tropicalis)


name: Degradation of TGF-beta receptor complex (Gallus gallus)


name: H(+)(out) + L-cysteine(in) + Na(+)(in) => H(+)(in) + L-cysteine(out) + Na(+)(out)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-2-O-methyl-sn-glycerol = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-2-O-methyl-3-(9Z)-octadecenoyl-sn-glycerol


name: CTLH E3 ligase ubiquitinates LDHA (Danio rerio)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Bos taurus)


name: 3 Na(+)(in) + selenate(in) => 3 Na(+)(out) + selenate(out)


name: SLIT2-bound ROBO1 binds MYO9B (Mus musculus)


name: UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 (Gallus gallus)


name: P2Y2 receptor binds ATP and UTP (Canis familiaris)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Drosophila melanogaster)


name: HSD11B2 dehydrogenates PREDL to PREDN (Rattus norvegicus)


name: Phosphorylation of Platelet Sec-1 (Sus scrofa)


name: ATP + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide <=> 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + diphosphate


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Drosophila melanogaster)


name: TNF-mediated dimerization of procaspase-8 (Sus scrofa)


name: DLD dimer dehydrogenates dihydrolipoyl (Canis familiaris)


name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Bos taurus)


name: a carboxylate(out) + nicotinate(in) => a carboxylate(in) + nicotinate(out)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Mus musculus)


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Homo sapiens)


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Drosophila melanogaster)


name: 2-demethylmenaquinone-8 + H(+) + NADH => 2-demethylmenaquinol-8 + NAD(+)


name: Receptor ACKR2 binds most inflammatory CC chemokines (Rattus norvegicus)


name: PLK1 phosphorylates GORASP1 (Sus scrofa)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Sus scrofa)


name: an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH => a (2S,3R)-flavan-3-ol + 2 NADP(+)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Drosophila melanogaster)


name: PA is dephosphorylated to DAG by LPIN (Plasmodium falciparum)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 <=> N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-glycine


name: SUMOylation of MKL1 with SUMO1 (Homo sapiens)


name: Autophosphorylation of PAK1,2,3 (Gallus gallus)


name: PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Sus scrofa)


name: 5-methyltetrahydropteroyltri-L-glutamate + L-selenohomocysteine = L-selenomethionine + tetrahydropteroyltri-L-glutamate


name: ADP(out) + ATP(in) + H(+)(out) + Mg(2+)(in) => ADP(in) + ATP(out) + H(+)(in) + Mg(2+)(out)


name: an archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate <=> an archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy- beta-D-glucuronosyl)-N-acetyl- alpha-D-glucosaminyl phosphate + H(+) + UDP


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + epi-cedrol


name: docosanoate + glycerol + H(+) => 1-docosanoylglycerol + H2O


name: [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose => [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + H(+) + UDP


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Xenopus tropicalis)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Homo sapiens)


name: GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Sus scrofa)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Sus scrofa)


name: ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) (Mus musculus)


name: H2O + L-glutamine = L-glutamate + NH4(+)


name: (9Z)-hexadecenoyl-CoA + 3-oxosphinganine => CoA + H(+) + N-(9Z-hexadecenoyl)-3-oxosphinganine


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Danio rerio)


name: (R)-4'-phosphopantothenate + H2O <=> (R)-pantothenate + phosphate


name: BIL dissociates from GSTA1, FABP1 (Bos taurus)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O => (N(2),N(2),N(7))-trimethyl-GMP + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+)


name: CHUK, IKBKB phosphorylate CYLD at S418 (Canis familiaris)


name: 3-phenylpyruvate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-phenylalanine


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Danio rerio)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Saccharomyces cerevisiae)


name: Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Rattus norvegicus)


name: calcium ion binding involved in regulation of cytosolic calcium ion concentration


name: AKT1S1 (PRAS40) binds mTORC1 (Drosophila melanogaster)


name: p-T68-CHEK2 autophosphorylates (Plasmodium falciparum)


name: PPM1L dephosphorylates multiphospho-CERT1-2 (Homo sapiens)


name: acetyl-[ACP] + CoA => acetyl-CoA + holo-[ACP]


name: H2O + N-(9Z-octadecenoyl)-L-lysine => (9Z)-octadecenoate + L-lysine


name: The PIDDosome binds CASP2 (Mus musculus)


name: Degradation of SMAD2/3:SMAD4 complex (Drosophila melanogaster)


name: depalmitoylated eNOS translocates from plasma membrane (Rattus norvegicus)


name: (S)-indan-1-ol + NADP(+) = H(+) + indan-1-one + NADPH


name: CO2 + H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NADP(+) => (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 3 H(+) + NADPH


name: TBXAS1 isomerises PGH2 to TXA2 (Homo sapiens)


name: adenosine(4220) in 28S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(4220) in 28S rRNA + S-adenosyl-L-homocysteine


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Bos taurus)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Bos taurus)


name: ICMT methylates S-Farn RAS proteins (Danio rerio)


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Mus musculus)


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Dictyostelium discoideum)


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O <=> 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate


name: chrodrimanin C + H(+) + NADPH + O2 => chrodrimanin H + H2O + NADP(+)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Canis familiaris)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Sus scrofa)


name: (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+) <=> (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Sus scrofa)


name: H2O2 + iminosuccinate => L-aspartate + O2


name: EPHX1 hydrates BaP4,5O to BaP4,5-DHD (Rattus norvegicus)


name: UIMC1 and FAM175A bind DNA DSBs (Gallus gallus)


name: (14E)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoyl-CoA + O2


name: PGLYRP3,4 binds bacterial peptidoglycan (Danio rerio)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 4beta-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (beta-L-Ara4N)2-(Kdo)2-lipid A(in) + ATP + H2O <=> (beta-L-Ara4N)2-(Kdo)2-lipid A(out) + ADP + H(+) + phosphate


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Mus musculus)


name: 2-oxoglutarate + heptyl sulfate + O2 <=> CO2 + H(+) + heptanal + succinate + sulfate


name: 2 D-glucopyranose 1-phosphate => D-glucose + D-glucose 1,6-bisphosphate


name: LARG activation by G alpha 12/13 (Gallus gallus)


name: (3R)-hydroxy-(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA = (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + H2O


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Gallus gallus)


name: HATs and coactivators are recruited to the CTSD gene (Homo sapiens)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Saccharomyces cerevisiae)


name: SLCO3A1 isoform 1 has abroad substrate specificity (Rattus norvegicus)


name: histidine => urocanate + NH4+ (Sus scrofa)


name: MeSeOH is reduced to MeSeH by TXNRD1 (Bos taurus)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Sus scrofa)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Caenorhabditis elegans)


name: interleukin-1 type II receptor antagonist activity


name: Phosphorylation of SRC-1 (Canis familiaris)


name: Activated FGFR4 mutants phosphorylate FRS2 (Homo sapiens)


name: (R)-lactate + NADP(+) <=> H(+) + NADPH + pyruvate


name: L-arginine(in) + L-glutamine(out) + Na(+)(out) = L-arginine(out) + L-glutamine(in) + Na(+)(in)


name: CYP4F11 16-hydroxylates 3OH-PALM (Danio rerio)


name: "cellulose 1,4-beta-cellobiosidase (non-reducing end)"


name: myo-inositol + stachyose => alpha-D-galactosyl-(1->3)-1D-myo-inositol + raffinose


name: Activated FGFR3 binds SHC1 (Drosophila melanogaster)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Canis familiaris)


name: AGK:Mg2+ phosphorylates MAG, DAG (Canis familiaris)


name: (R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Bos taurus)


name: GST dimers conjugate GSH with cytosolic substrates (Homo sapiens)


name: Interaction of Tie2 with Ang2 (Danio rerio)


name: CHST14 transfers SO4(2-) to GalNAc in dermatan or DS (Bos taurus)


name: p-T,Y MAPK dimers translocate to nucleus (Canis familiaris)


name: H2O + sepiapterin = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+)


name: [DsrC protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide = [DsrC protein]-dithiol + 2 AH2 + H(+) + sulfite


name: E2F1/E2F2/E2F3 and SP1 stimulate transcription of p14ARF mRNA (Homo sapiens)


name: Synthesis of GABA by GAD2 (Gallus gallus)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+)


name: 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD(+) = 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: carbamoyl phosphate + L-lysine => H(+) + L-homocitrulline + phosphate


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Sus scrofa)


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Homo sapiens)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Danio rerio)


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Gallus gallus)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Sus scrofa)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Canis familiaris)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Canis familiaris)


name: an S-substituted L-cysteinylglycine + H2O <=> an S-substituted L-cysteine + glycine


name: 3-oxopropanoyl-CoA + methanethiol => 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA


name: complement component C3dg receptor activity


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Sus scrofa)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Mus musculus)


name: CO2 + gibberellin A24 + H2O + succinate => 2-oxoglutarate + gibberellin A15 + O2


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate = adenosine 5'-tetraphosphate + AMP + 2 H(+)


name: H2O + O2 + sarcosine = glyoxylate + H2O2 + methylamine


name: ALDH8A1 oxidises 9cRAL to 9cRA (Bos taurus)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Gallus gallus)


name: Extracellular KSPG translocates to the lysosome for degradation (Homo sapiens)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Mus musculus)


name: Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Sus scrofa)


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Mus musculus)


name: acetyl-CoA + D-glucosamine => CoA + H(+) + N-acetyl-D-glucosamine


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: (3R)-hydroxyoctadecanoyl-CoA + NAD(+) => 3-oxooctadecanoyl-CoA + H(+) + NADH


name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoylglycerol


name: Androgens binds AR (in the HSP90 chaperone complex) (Homo sapiens)


name: H(+) + NADH + O2 + terephthalate <=> (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Mus musculus)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] (Rattus norvegicus)


name: GALK1 phosphorylates Gal to Gal1P (Danio rerio)


name: SLC2A5 transports fructose from extracellular region to cytosol (Mus musculus)


name: 20alpha-hydroxy-5beta-pregnan-3-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH


name: Rag dimer formation (Dictyostelium discoideum)


name: NT5C2 tetramer phosphorylates RBV (Mus musculus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Dictyostelium discoideum)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Caenorhabditis elegans)


name: SPAM1 Binds Hyaluronic Acid (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+)


name: 3-dehydro-L-gulonate 6-phosphate + ADP + H(+) => 3-dehydro-L-gulonate + ATP


name: (2Z,6E)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate


name: AMP + H(+) + octadecanoyl-[(hydroxy)phthioceranic acid synthase] => holo-[(hydroxy)phthioceranic acid synthase] + octadecanoyl-AMP


name: D-ribose + H(+) + nicotinamide => beta-nicotinamide D-riboside + H2O


name: SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Bos taurus)


name: (S)-2-ureidoglycine + H2O <=> glyoxylate + NH4(+) + urea


name: ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Gallus gallus)


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Bos taurus)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Plasmodium falciparum)


name: NPC transports GCK1:GKRP from cytosol to nucleoplasm (Rattus norvegicus)


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Xenopus tropicalis)


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Saccharomyces cerevisiae)


name: UDP-alpha-D-galactose(in) + UDP-alpha-D-glucose(out) = UDP-alpha-D-galactose(out) + UDP-alpha-D-glucose(in)


name: (+)-minovincinine + acetyl-CoA = (+)-echitovenine + CoA


name: an aromatic aldehyde + H2O + O2 <=> an aromatic carboxylate + H(+) + H2O2


name: Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Homo sapiens)


name: a 2-oxocarboxylate + H(+) + NADPH => a (2S)-2-hydroxycarboxylate + NADP(+)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Rattus norvegicus)


name: CRABP1 binds atRA (Drosophila melanogaster)


name: 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)


name: MLKL binds IP4, IP5 and IP6  (Homo sapiens)


name: 7-chlorotetracycline + H(+) + NADPH + O2 <=> (1S,10S,10aS)-3-(CONH2)-9-Cl-1-(Me2N)-3,3a,4,10-(HO)4-10-Me-2,5-dioxo-1H,10aH,11H,11aH-cyclopenta[b]anthracen-6-olate + CO + H2O + NADP(+)


name: Mg-protoporphyrin IX + S-adenosyl-L-methionine => Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine


name: ATP + glutathione(in) + H2O => ADP + glutathione(out) + H(+) + phosphate


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Gallus gallus)


name: Gbeta:gamma recruits PI3K gamma (Bos taurus)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Xenopus tropicalis)


name: CREBBP, EP300 acetylates NFE2L2 (Xenopus tropicalis)


name: NADPH + O2 + senecionine <=> H2O + NADP(+) + senecionine N-oxide


name: p-BMAL1:p-CLOCK,NPAS2 binds CRY1 gene (Homo sapiens)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Dictyostelium discoideum)


name: A + cis-4-hydroxy-D-proline => 4-hydroxy-1-pyrroline-2-carboxylate + AH2 + H(+)


name: PIAS1 SUMOylates THRB with SUMO1. (Mus musculus)


name: H2O + O-phospho-L-seryl-tRNA(Sec) + selenophosphate <=> L-selenocysteinyl-tRNA(Sec) + 2 phosphate


name: dopamine neurotransmitter receptor activity, coupled via Gs


name: ULK1 Translocates to the mitochondria (Sus scrofa)


name: BRCA1-A complex deubiquitinates K63polyUb-histone H2A (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1-(9Z)-octadecenoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: L-glutamate(out) + L-thyroxine(in) => L-glutamate(in) + L-thyroxine(out)


name: (2R)-2-(4-aminophenyl)-L-seryl-[peptidyl-carrier protein] + A + H2O => 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AH2 + O2


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Drosophila melanogaster)


name: L-serine + succinyl-CoA <=> CoA + O-succinyl-L-serine


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Bos taurus)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Canis familiaris)


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Mus musculus)


name: NT5C2 tetramer dephosphorylates RBV-MP (Gallus gallus)


name: Fibrillin-1 binds latent TGF-beta (Mus musculus)


name: Spermine  => N-acetylated spermine (Sus scrofa)


name: uridine(516) in 16S rRNA <=> pseudouridine(516) in 16S rRNA


name: an N-acyl-D-mannosamine 6-phosphate + H2O + phosphoenolpyruvate <=> an N-acylneuraminate 9-phosphate + phosphate


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Sus scrofa)


name: NSF and SNAPs bind the cis-SNARE at the Golgi (Mus musculus)


name: daphnin + H(+) + UDP => 7,8-dihydroxycoumarin + UDP-alpha-D-glucose


name: 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+)


name: Synthesis of PIP3 from PIP2 by PI3K (Homo sapiens)


name: Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL (Bos taurus)


name: NAA translocates from mitochondrial matrix to cytosol (Homo sapiens)


name: ABC-type ferric-enterobactin transporter activity


name: 4-methylajmaline + H(+) + S-adenosyl-L-homocysteine => 4-methylnorajmaline + S-adenosyl-L-methionine


name: Ghrelin O-acyltransferase decanoylates Proghrelin (Rattus norvegicus)


name: HTMLYS translocates from the mitochondrial matrix to the cytosol (Homo sapiens)


name: chromate transmembrane transporter activity


name: 4-amino-L-phenylalanine + S-adenosyl-L-methionine => 4-methylamino-L-phenylalanine + H(+) + S-adenosyl-L-homocysteine


name: 5alpha-androst-1-ene-3,17-dione + AH2 => 5alpha-androstan-3,17-dione + A


name: 5S-HpETE is dehydrated to LTA4 by ALOX5 (Homo sapiens)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Danio rerio)


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Homo sapiens)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Dictyostelium discoideum)


name: GST dimers cleave AZA to 6MP (Danio rerio)


name: Autophagosome maturation (Schizosaccharomyces pombe)


name: L-threonine transmembrane transporter activity


name: PalmS-ESRs:CAVs translocate to plasma membrane (Bos taurus)


name: Activation of STAT5a/b by JAK2 (Sus scrofa)


name: IKBKG subunit of IKK complex binds polyubiquinated RIP1 (Homo sapiens)


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Caenorhabditis elegans)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Drosophila melanogaster)


name: 3-(aminomethyl)indole + 2 S-adenosyl-L-methionine = gramine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)


name: H2O + NADP(+) + vanillin = 2 H(+) + NADPH + vanillate


name: CREB3L1 translocates from the cytosol to the nucleus (Homo sapiens)


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Bos taurus)


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Sus scrofa)


name: Activated FGFR1 binds FLRT1,2,3 (Rattus norvegicus)


name: Proteinase-activated receptors can bind thrombin (Bos taurus)


name: (E)-isoeugenol + S-adenosyl-L-methionine <=> (E)-isomethyleugenol + H(+) + S-adenosyl-L-homocysteine


name: G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Bos taurus)


name: CDK2:CCNA phosphorylates TERF2 (Bos taurus)


name: NPAS4 binds RBFOX3 (NeuN) gene promoter (Homo sapiens)


name: H2O + N(omega)-phospho-L-arginyl-[protein] => L-arginyl-[protein] + phosphate


name: 17-dehydrostemmadenine + NADP(+) => 3,17-didehydrostemmadenine + NADPH


name: CD320-mediated TCN2:RCbl uptake and delivery to lysosome (Mus musculus)


name: ATP + hydroxylamine + L-glutamate => ADP + L-glutamine hydroxamate + phosphate


name: (6S)-6-amino-3,3-dimethyl-2-oxoheptanedioate = (2S)-5,5-dimethyl-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(+) + H2O


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Xenopus tropicalis)


name: PPP1R3C binds to glycogen:GYG1:GYS1 (Saccharomyces cerevisiae)


name: ATP + H2O + N-[(S)-lactoyl]-L-phenylalanine(in) = ADP + H(+) + N-[(S)-lactoyl]-L-phenylalanine(out) + phosphate


name: 3-oxopropanoyl-CoA + H2O => 3-oxopropanoate + CoA + H(+)


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Bos taurus)


name: H(+) + myricetin 3-O-alpha-L-rhamnoside + UDP => myricetin + UDP-beta-L-rhamnose


name: Autophosphorylation and activation of CAMK2 (Gallus gallus)


name: TYRP1 oxidises DHICA to IQCA (Bos taurus)


name: FMO3:FAD N-oxidises TMA to TMAO (Rattus norvegicus)


name: a quinone + L-quinate <=> 3-dehydroquinate + a quinol


name: MTRR reduces cob(II)alamin to meCbl (Dictyostelium discoideum)


name: A + beta-cyclopiazonate <=> AH2 + alpha-cyclopiazonate


name: (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => CoA + H2O


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Homo sapiens)


name: 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine => 8-demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Mus musculus)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Bos taurus)


name: FANCD2 deubiquitination by USP1:WDR48 (Rattus norvegicus)


name: an N(2)-(1-hydroxy-2-oxoethyl)-guanosine in RNA + H2O <=> a guanosine in RNA + glycolate + H(+)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2 <=> 2-dehydro-D-glucose + H2O2 + L-glutamate


name: D-glucose 6-phosphate + NAD(+) => 6-phospho-D-glucono-1,5-lactone + H(+) + NADH


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O => a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Xenopus tropicalis)


name: TRIF:activated TLR3/TLR4 complex recruits RIP1 (Sus scrofa)


name: a ganglioside GD1a + N-acetylneuraminate => a ganglioside GT1a + H2O


name: Beta-catenin translocates to the nucleus (Bos taurus)


name: (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[phycoerythrocyanin beta-subunit] => phycocyanobilin-L-cysteinyl(84)-[phycoerythrocyanin beta-subunit]


name: Degradation of ubiquitinated SMAD2 (Sus scrofa)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O <=> a 1,2-diacyl-sn-glycerol + H(+) + sn-glycerol 3-phosphate


name: DVL is recruited to the receptor (Danio rerio)


name: 2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate) + ADP + H(+)


name: ATP + H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out) <=> ADP + H(+) + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) + phosphate


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecylglycerol


name: choline + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = betaine aldehyde hydrate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: chlorogenate + H2O = (E)-caffeate + H(+) + L-quinate


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate => diphosphate + longifolene


name: Activation of STAT5a/b by JAK2 (Mus musculus)


name: CFTR binds components of the ERAD machinery for ubiquitination and degradation (Sus scrofa)


name: 5-amino-6-(D-ribitylamino)uracil + methylglyoxal = 5-(2-oxopropylideneamino)-6-(D-ribitylamino)uracil + H2O


name: (2Z,6Z)-farnesyl diphosphate = beta-bisabolene + diphosphate


name: H(+) + N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine => N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine


name: GNB2L1 binds IKKA:IKKB:NEMO (Homo sapiens)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] (Canis familiaris)


name: ATP + L-threonyl-[tau protein] = ADP + H(+) + O-phospho-L-threonyl-[tau protein]


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Drosophila melanogaster)


name: Direct recruitment of PI3K to p-KIT (Xenopus tropicalis)


name: Caveolin-1 binds Basigin (Xenopus tropicalis)


name: beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol <=> cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine


name: Monoubiquitination of FANCD2:FANCI (Rattus norvegicus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester => a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol


name: N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + 3 UDP-N-acetyl-alpha-D-galactosamine => [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + 3 H(+) + 3 UDP


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Homo sapiens)


name: H2O + L-cysteinyl-[sulfatase] + S-adenosyl-L-methionine <=> 3-oxo-L-alanyl-[sulfatase] + 5'-deoxyadenosine + 2 H(+) + hydrogen sulfide + L-methionine


name: (6S)-5,6,7,8-tetrahydrofolate + S,S-dimethyl-beta-propiothetin <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 3-(methylsulfanyl)propanoate + H(+)


name: 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Rattus norvegicus)


name: Dual mechanism MAPK inhibitors bind MAPKs (Homo sapiens)


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Danio rerio)


name: E2F1 gene transcription is inhibited by E2F6 (Homo sapiens)


name: 3-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 3,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ASAP1 stimulates GTPase activity of ARF4 (Rattus norvegicus)


name: (3S)-versiconol acetate + H2O = (S)-versiconol + acetate + H(+)


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Sus scrofa)


name: 2 a Fe(III)-siderophore + NADH => 2 a Fe(II)-siderophore + H(+) + NAD(+)


name: dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2


name: Active ALK recruits PI3K (Canis familiaris)


name: chlorophyll b + H(+) + NADPH => 7(1)-hydroxychlorophyll a + NADP(+)


name: Latent TGF-beta-3 binds integrins (Xenopus tropicalis)


name: (Z)-2-phenyl-1-thioacetohydroximate + UDP-alpha-D-glucose => (Z)-desulfoglucotropeolin + UDP


name: tetracycline transmembrane transporter activity


name: Active MTORC1 phosphorylates ULK1 (Xenopus tropicalis)


name: RSF complex binds the centromere (Homo sapiens)


name: divinyl chlorophyllide a 8-vinyl-reductase activity


name: USP21 deubiquitinates RIPK1,DDX58 (Caenorhabditis elegans)


name: Tyrosine is monoiodinated (Drosophila melanogaster)


name: Hemoglobin A is protonated and carbamated causing release of oxygen (Rattus norvegicus)


name: HDAC3 containing complexes deacetylate histone (Saccharomyces cerevisiae)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Dictyostelium discoideum)


name: RAC1:GTP binds NOX1 complex (Homo sapiens)


name: 6-phospho-2-dehydro-D-gluconate + H(+) + NADPH => 6-phospho-D-gluconate + NADP(+)


name: NEIL1 cleaves DHU from damaged DNA (Bos taurus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Drosophila melanogaster)


name: p-4Y-SIRPA:CD47 binds PTK2B (Rattus norvegicus)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) => (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Homo sapiens)


name: cytidine(32) in tRNA(Ser) + S-adenosyl-L-methionine => H(+) + N(3)-methylcytidine(32) in tRNA(Ser) + S-adenosyl-L-homocysteine


name: FAD attaches to SDHA (Rattus norvegicus)


name: 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+) => H2O + L-methionine + O2


name: ent-7alpha-hydroxykaur-16-en-19-oate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => gibberellin A12 aldehyde + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Aquaporins passively transport water out of cells (Caenorhabditis elegans)


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Canis familiaris)


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Bos taurus)


name: MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Bos taurus)


name: SEC31:SEC13 and v-SNARE recruitment (Sus scrofa)


name: an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA


name: "Activator" RAF:YWHAB dimer binds RAS:GTP (Caenorhabditis elegans)


name: CYP3A4, CYP2B6 bind ritonavir (Xenopus tropicalis)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Rattus norvegicus)


name: Serum albumin binds 2-lysophosphatidylcholine (Rattus norvegicus)


name: H2O + L-arabino-1,4-lactone 5-phosphate = 5-phospho-L-arabinonate + H(+)


name: choline + H(+) + NADH + O2 => glycolaldehyde + H2O + NAD(+) + trimethylamine


name: FMO3:FAD N-oxidises TMA to TMAO (Mus musculus)


name: intermediate voltage-gated calcium channel activity


name: (omega-1)-methyl-3-oxo-fatty acyl-CoA + H(+) + NADPH => (omega-1)-methyl-(3R)-hydroxy-fatty acyl-CoA + NADP(+)


name: POM121 binds the Nup107-Nup160 complex (Gallus gallus)


name: 7-oxoresolvin D2 + H(+) + NADH => NAD(+) + resolvin D2


name: (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: AURKA phosphorylates PLK1 (Gallus gallus)


name: AJUBA facilitates AURKA autophosphorylation (Homo sapiens)


name: SLC44A1 transports Cho from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H(+) + NADPH = (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + NADP(+)


name: 8-hydroxycopalyl diphosphate => (13R)-manoyl oxide + diphosphate


name: TNF-α:TNFR1 binds NSMAF (Rattus norvegicus)


name: naphtopyrone YWA1 <=> H(+) + H2O + norrubrofusarin


name: Caspase-8 processing in the DISC (Homo sapiens)


name: a ganglioside Ac-O-7-GD1a (d18:1(4E)) = a ganglioside Ac-O-8-GD1a (d18:1(4E))


name: RIC1:RGP1 recruits RAB6:GDP to the TGN (Homo sapiens)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Mus musculus)


name: Aggrecan binds Hyaluronan and HAPLN1 (Rattus norvegicus)


name: BGN binds Collagen types I, VI, (IX) (Sus scrofa)


name: Activated NTRK2 binds FRS2 (Homo sapiens)


name: PTK6 phosphorylates KHDRBS1 (Danio rerio)


name: RHOD binds effectors at the endosome membrane (Sus scrofa)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Bos taurus)


name: GSS:Mg2+ dimer synthesizes GSH (Saccharomyces cerevisiae)


name: Beta-catenin binds SOX proteins (Bos taurus)


name: Autocatalytic activation of proMMP13 (Mus musculus)


name: VWF multimer binds to collagen type I (Xenopus tropicalis)


name: IRAK1 binds to MYD88 within the IL1R complex (Sus scrofa)


name: Expression of TFAP2C in primordial germ cells (Homo sapiens)


name: n H(+)(in) + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) => n H(+)(out) + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out)


name: Abortive Initiation Before Second Transition (Saccharomyces cerevisiae)


name: ATP + kanosamine => ADP + D-kanosamine 6-phosphate + H(+)


name: deoxycohumulone + dimethylallyl diphosphate = colupulone + diphosphate + H(+)


name: alachlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + methyl formate + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin]


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Plasmodium falciparum)


name: Association of Cyclin A with the APC/C (Sus scrofa)


name: PINK1 phosphorylates Ub on MOM proteins (Sus scrofa)


name: 2'-deoxyuridine + ATP = ADP + dUMP + H(+)


name: p-S207 KARS displaces HINT1 (Sus scrofa)


name: SREBP1A,1C,2 binds SCAP:INSIG:oxysterol and is retained in the endoplasmic reticulum (Homo sapiens)


name: Beclin-1 complex translocates to the ER (Sus scrofa)


name: 2 ATP + 2 cob(II)alamin + 2 H2O + reduced [electron-transfer flavoprotein] => 2 adenosylcob(III)alamin + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate


name: CHUK, IKBKB and IKBKG form IKK complex (Canis familiaris)


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Canis familiaris)


name: NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP (Mus musculus)


name: NADP(+) + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H(+) + NADPH


name: MECP2 binds the PTPN4 gene promoter (Homo sapiens)


name: glycodeoxycholate(in) + 2 Na(+)(in) => glycodeoxycholate(out) + 2 Na(+)(out)


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Gallus gallus)


name: cyanophycin synthetase activity (L-aspartate-adding)


name: 2 3,4,5-trihydroxybenzoate + H(+) => digallate + H2O


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Dictyostelium discoideum)


name: inositol monophosphate 4-phosphatase activity


name: RUNX1 binds the core TAL1 complex (Drosophila melanogaster)


name: Fibrillin-1 binds integrins (Canis familiaris)


name: Delta(9)-tetrahydrocannabinolate + H2O2 => cannabigerolate + O2


name: 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine + H2O <=> 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + choline + H(+)


name: 5,10-methylenetetrahydromethanopterin + glycine + H2O = 5,6,7,8-tetrahydromethanopterin + L-serine


name: (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA + H(+) + NADPH => (23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA + NADP(+)


name: Formation of Okazaki fragments (Mus musculus)


name: (R)-carnitine + hexadecanedioyl-CoA => CoA + O-hexadecanedioyl-L-carnitine


name: MIB2 ubiquitinates CYLD at K338, K530 (Drosophila melanogaster)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Plasmodium falciparum)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Caenorhabditis elegans)


name: 2 H(+) + 2 NADH + 2 O2 + tetracenomycin A2 => H2O + 2 NAD(+) + tetracenomycin C


name: H(+) + UDP-alpha-D-galacturonate => CO2 + UDP-beta-L-arabinopyranose


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Bos taurus)


name: SLP-76 stimulates PLC gamma 2 (Drosophila melanogaster)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)


name: PNPLA6 hydrolyzes LysoPtdCho (Caenorhabditis elegans)


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Plasmodium falciparum)


name: CYP1A2 hydroxylates AFB1 to AFM1 (Mus musculus)


name: (+)-kolavenyl diphosphate + H2O = (+)-kolavelool + diphosphate


name: 6-deoxy-6-sulfo-D-fructose 1-phosphate => (2S)-3-sulfolactaldehyde + dihydroxyacetone phosphate


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 => N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-taurine


name: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Drosophila melanogaster)


name: thiosulfate dehydrogenase (quinone) activity


name: Guanine nucleotide exchange on RAL (Homo sapiens)


name: NEK9 binds NEK6/NEK7 in the cytosol (Bos taurus)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Bos taurus)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Homo sapiens)


name: Recruitment of GADS:SLP-76 to p-5Y-LAT (Canis familiaris)


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Danio rerio)


name: 4-CDP-2-C-methyl-D-erythritol <=> 2-C-methyl-D-erythritol 3,4-cyclophosphate + CMP + H(+)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O <=> 2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate