name: GNRHR binds chemical antagonists (Homo sapiens)


name: BTK in active Gq-BTK complex is activated (Canis familiaris)


name: 3-methylbutanol + NADP(+) => 3-methylbutanal + H(+) + NADPH


name: p-S MAPK6,4 phosphorylate MAPKAPK5 (Homo sapiens)


name: PTK2beta binds alphaVbeta3 (Mus musculus)


name: ARL1 recruits TGN Golgin homodimers (Bos taurus)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Bos taurus)


name: Binding of cAMP to HCN channels (Bos taurus)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Sus scrofa)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: all-trans-4-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> all-trans-4-oxoretinoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Activation of DAkt1 by DPDK1 (Drosophila melanogaster)


name: phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] (Gallus gallus)


name: Secretion and activation of the latent large complex of TGF-beta-1 (Gallus gallus)


name: a ganglioside GM1b (d18:1(4E)) + H2O = a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate


name: PC is converted to PS by PTDSS1 (Caenorhabditis elegans)


name: PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Mus musculus)


name: 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine + AH2 => 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine + A + H2O


name: B3GALT4 transfers Gal to gangliosides (Drosophila melanogaster)


name: benzoate + H(+) + NADH + O2 => (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: hexadecasphinganine + NADP(+) => 3-oxohexadecasphinganine + H(+) + NADPH


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-cinerolone => cinerin I + CoA


name: [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + NADP(+) + phosphate <=> [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + H(+) + NADPH


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + CoA


name: CBL dissociates from ubiquitinated p-SPRY2 (Mus musculus)


name: 3-dehydroquinate + a quinol => a quinone + L-quinate


name: 3-sulfino-L-alanine(out) + H(+)(in) + L-glutamate(in) <=> 3-sulfino-L-alanine(in) + H(+)(out) + L-glutamate(out)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-seryl-[protein] + UDP


name: FADH2-C4alpha-hydroperoxide + NADPH + rifampicin => FADH2 + H(+) + H2O + NADP(+) + rifampicin hemiaminal


name: (9Z)-hexadecenoate + NH4(+) => (9Z)-hexadecenamide + H2O


name: COQ3 methylates DeMQ10H2 (Saccharomyces cerevisiae)


name: MTRR reduces cob(II)alamin to meCbl (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-choline = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: glutarate(out) + glycocholate(in) => glutarate(in) + glycocholate(out)


name: PHGDH tetramer dehydrogenates 3PG (Bos taurus)


name: (3S)-3-hydroxybutanoyl-CoA + H2O <=> (S)-3-hydroxybutanoate + CoA + H(+)


name: PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Bos taurus)


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Mus musculus)


name: DPP4 binds DPP4 inhibitors (Canis familiaris)


name: ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Caenorhabditis elegans)


name: 26-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase] => 26-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Rattus norvegicus)


name: diphosphate + labd-13(16),14-diene-9-ol => peregrinol diphosphate


name: p62 is recruited and forms a complex with TRAF6 (Danio rerio)


name: Assembly of hexameric IL-6 receptor (Xenopus tropicalis)


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Canis familiaris)


name: HEXB cleaves the terminal GalNAc from small HA fragments (Mus musculus)


name: Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA (Homo sapiens)


name: beta-D-fructose 1-phosphate + methylglyoxal => 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + D-glyceraldehyde


name: a 3-oxo-fatty acyl-CoA + H(+) + NADPH => a 3-hydroxy-fatty acyl-CoA + NADP(+)


name: S-adenosyl 3-(methylsulfanyl)propylamine + spermine <=> H(+) + N(4)-aminopropylspermine + S-methyl-5'-thioadenosine


name: CO2 + H2O + NADP(+) + naphthalene-1,2-diol => 1-hydroxy-2-naphthoate + 2 H(+) + NADPH + O2


name: Activated FGFR4 phosphorylates SHC1 (Xenopus tropicalis)


name: RDH8 reduces atRAL to atROL (Homo sapiens)


name: IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Sus scrofa)


name: chloroacetaldehyde + H2O + NADP(+) <=> chloroacetate + 2 H(+) + NADPH


name: alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride + H2O => inulobiose


name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Dictyostelium discoideum)


name: (E)-caffeoyl-AMP + CoA = (E)-caffeoyl-CoA + AMP + H(+)


name: (11R)-methyl carlactonoate + S-adenosyl-L-homocysteine => (11R)-carlactonoate + S-adenosyl-L-methionine


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Rattus norvegicus)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Xenopus tropicalis)


name: a ganglioside Ac-O-8-GD2(d18:1(4E)) => a ganglioside Ac-O-9-GD2(d18:1(4E))


name: 3-(2-aminophenyl)succinyl-CoA + succinate => (2-aminophenyl)succinate + succinyl-CoA


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H(+) + NADPH => CDP-alpha-D-paratose + NADP(+)


name: NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP (Drosophila melanogaster)


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Gallus gallus)


name: Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Sus scrofa)


name: CREBBP acetylates HINT1 dimer (Bos taurus)


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Canis familiaris)


name: POLK incorporates dNMP opposite to damaged DNA base (Mus musculus)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Bos taurus)


name: Loading of dopamine into synaptic veiscles (Mus musculus)


name: JUNB dimer binds GZMB promoter (Homo sapiens)


name: VWF multimer binds to collagen type I (Bos taurus)


name: SPHK1 phosphorylates sphingosine in response to E2 stimulation (Saccharomyces cerevisiae)


name: FGFR1c binds to FGF (Caenorhabditis elegans)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Bos taurus)


name: RHOD GAPs stimulate RHOD GTPase activity (Canis familiaris)


name: Translocation of Cdc25B to the cytoplasm (Bos taurus)


name: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2 reduced [2Fe-2S]-[ferredoxin]


name: PKN1 stimulates association of AR with NCOA2 (Mus musculus)


name: H(+) + NADPH + 2 phytyl diphosphate <=> (14E,18E)-lycopadiene + 2 diphosphate + NADP(+)


name: AMP + diphosphate + L-glutamyl-tRNA(Gln) => ATP + L-glutamate + tRNA(Glu)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Gallus gallus)


name: NEK6/NEK7 phosphorylates NUP98 (Homo sapiens)


name: RHOA:GTP:RTKN binds LIN7B (Caenorhabditis elegans)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Sus scrofa)


name: Necl-1:Necl-2 trans heterodimer interaction (Sus scrofa)


name: NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 (Bos taurus)


name: Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Caenorhabditis elegans)


name: H2O + hexylamine + NAD(+) = H(+) + hexanal + NADH + NH4(+)


name: SUMOylation of NR3C1 (GR) with SUMO1 (Danio rerio)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Sus scrofa)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Bos taurus)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)


name: B3GAT dimers transfer GlcA to tetrasaccharide linker (Caenorhabditis elegans)


name: ACO1 binds 4Fe-4S (Plasmodium falciparum)


name: H2O + leukotriene A4 => (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Dictyostelium discoideum)


name: Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)


name: PTEN dephosphorylates PIP3 (Danio rerio)


name: CK2 phosphorylates condensin I subunits (Mus musculus)


name: (6Z)-octenoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(6Z-octenoyl)-4'-phosphopantetheine


name: acetyl-CoA + octadecanoyl-CoA = 3-oxoeicosanoyl-CoA + CoA


name: biphenyl-2,3-diol + H2O + NAD(+) => biphenyl-2-ol + H(+) + NADH + O2


name: angiotensin II + H2O = angiotensin-(1-7) + L-phenylalanine


name: 2 H(+) + hexadecanoyl-[ACP] + 2 NADPH = hexadecan-1-ol + holo-[ACP] + 2 NADP(+)


name: (S)-2-chloropropanoate + H2O = (R)-lactate + chloride + H(+)


name: 3'-L-prolyl-AMP + diphosphate => ATP + L-proline


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Bos taurus)


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Canis familiaris)


name: IMP + NADP(+) + NH4(+) <=> GMP + 2 H(+) + NADPH


name: MET phosphorylates PTK2 (Caenorhabditis elegans)


name: (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H(+) + NADH => (3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA + NAD(+)


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Bos taurus)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Canis familiaris)


name: 2 (E)-4-coumaroyl-CoA + spermidine <=> 2 CoA + 2 H(+) + N(1),N(8)-bis(coumaroyl)-spermidine


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Homo sapiens)


name: SUMO-p-N protein dimer binds genomic RNA (Homo sapiens)


name: acetylsalicylate + H2O = acetate + H(+) + salicylate


name: 3-methylpentanoate + ATP + CoA <=> 3-methylpentanoyl-CoA + AMP + diphosphate


name: 5-amino-6-(D-ribitylamino)uracil + phosphate => 5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O


name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen


name: CHGA-derived peptide binds the bacterial cell surface (Canis familiaris)


name: O2 + reduced [NADPH--hemoprotein reductase] + sophoraflavanone B = H(+) + H2O + leachianone G + oxidized [NADPH--hemoprotein reductase]


name: a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + H(+) + UDP


name: PPT1 hydrolyses palmitoylated proteins (Rattus norvegicus)


name: (R)-mandelamide + H2O = (R)-mandelate + NH4(+)


name: NTP Binds Active Site of RNA Polymerase II (Schizosaccharomyces pombe)


name: Tyrosine is hydroxylated to dopa (Bos taurus)


name: Activation of claspin (Drosophila melanogaster)


name: (S)-malate(out) + malonate(in) => (S)-malate(in) + malonate(out)


name: FA2H hydroxylates 1,2-saturated fatty acids (Canis familiaris)


name: first spliceosomal transesterification activity


name: Activation of proMMP8 (Rattus norvegicus)


name: menaquinone-4 + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + omega-hydroxymenaquinone-4 + oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA <=> 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: a 1,2-diacylglycerol + H2O = a 2-acylglycerol + a carboxylate + H(+)


name: (R)-pantothenate(out) + 2 Na(+)(out) <=> (R)-pantothenate(in) + 2 Na(+)(in)


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate => ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Mus musculus)


name: ACY1:Zn2+ dimer hydrolyses mercapturic acids (Homo sapiens)


name: 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine = [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Rattus norvegicus)


name: NFE2L2 and MAFG bind the SQSTM1 gene (Homo sapiens)


name: [DsrC protein]-disulfide + 3 AH2 + 2 H(+) + sulfite => [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O


name: H2O + N-octadecanoylsphing-4-enine => octadecanoate + sphing-4-enine


name: MAPKs phosphorylate ETS1 and ETS2 (Danio rerio)


name: N-terminal L-glutaminyl-[peptide] <=> N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA => 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Rattus norvegicus)


name: 3beta-hydroxy-5beta-pregnane-20-one + H(+) + NADPH = 3beta,20alpha-dihydroxy-5beta-pregnane + NADP(+)


name: AMP + diphosphate + IC-asc-C7-CoA => ATP + CoA + IC-asc-C7


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O <=> (-)-geosmin + acetone


name: ATP + UTP => 2',3'-cUAMP + 2 diphosphate


name: Cleavage of uracil by SMUG1 glycosylase (Bos taurus)


name: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] => 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling (Rattus norvegicus)


name: USP7 deubiquitinates monoubiquitinated PTEN (Dictyostelium discoideum)


name: 4-hydroxy-3-all-trans-nonaprenylbenzoate + diphosphate => 4-hydroxybenzoate + all-trans-nonaprenyl diphosphate


name: CoA + O-(9Z)-tetradecenoyl-(R)-carnitine => (9Z)-tetradecenoyl-CoA + (R)-carnitine


name: NDUF subunits bind to form the IP subcomplex (Rattus norvegicus)


name: MET phosphorylates STAT3 (Xenopus tropicalis)


name: H2O + S-sulfosulfanyl-L-cysteinyl-[SoxY protein] <=> H(+) + S-sulfanyl-L-cysteinyl-[SoxY protein] + sulfate


name: IL34 dimer:SDC1 binds CSF1R (Gallus gallus)


name: Abortive Initiation Before Second Transition (Mus musculus)


name: MST1R autophosphorylates (Rattus norvegicus)


name: ATP + propanoate = ADP + propanoyl phosphate


name: CoA + H(+) + N-acetyl-L-aspartate => acetyl-CoA + L-aspartate


name: Dephosphorylation of inactive SRC by PTPB1 (Canis familiaris)


name: PC is converted to PS by PTDSS1 (Plasmodium falciparum)


name: SDHA:SDHB binds to SDHC:SDHD (Homo sapiens)


name: (S)-4-hydroxy-2-oxohexanoate <=> propanal + pyruvate


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Bos taurus)


name: uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid (Sus scrofa)


name: cortisone + H(+) + NADPH = 20beta-dihydrocortisone + NADP(+)


name: H(+) + N,N-dihydroxy-L-dihomomethionine => (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: SCRIB is required for asymmetric membrane localization of VANGL2 (Homo sapiens)


name: Collagen type XIII binds Integrin alpha1beta1 (Homo sapiens)


name: TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)


name: ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 (Canis familiaris)


name: glyoxylate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + glycine


name: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate = (Z)-alpha-bisabolene + diphosphate


name: CHEK1 phosphorylates E2F6 (Canis familiaris)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Bos taurus)


name: Translocation of WWTR1 (TAZ) to the nucleus (Xenopus tropicalis)


name: RBP3 regulates the transport of atROL from ROS to RPE (Xenopus tropicalis)


name: Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Mus musculus)


name: 2-hydroxy-2-methylpropanenitrile <=> acetone + hydrogen cyanide


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Sus scrofa)


name: 3'-phosphoadenylyl sulfate + 4-isopropylphenol = 4-isopropylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: dimethylallyl diphosphate + 2 isopentenyl diphosphate = (2Z,6Z)-farnesyl diphosphate + 2 diphosphate


name: 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+) => 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O


name: a ganglioside Ac-O-9-GD2 => a ganglioside Ac-O-8-GD2


name: ATP + cycloheximide(in) + H2O <=> ADP + cycloheximide(out) + H(+) + phosphate


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Canis familiaris)


name: PAPP-A2 proteolyzes IGF:IGFBP5:ALS (Danio rerio)


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: tetraketide alpha-pyrone synthase activity


name: campestanol + O2 + reduced [NADPH--hemoprotein reductase] => 6-deoxycathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate + H2O <=> 10-epi-gamma-eudesmol + diphosphate


name: NTPDase7 hydrolyzes nucleoside triphosphates (Homo sapiens)


name: ent-kaur-16-ene + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] = ent-kaur-16-en-19-oate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2 (Homo sapiens)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Gallus gallus)


name: guanosine 3',5'-bis(diphosphate) + H(+) + phosphate => guanosine 3'-diphosphate 5'-triphosphate + H2O


name: PRMT1 arginine-methylates RUNX1 (Bos taurus)


name: 4-hydroxybenzaldehyde + acetate => (E)-4-coumarate + H2O


name: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-alpha-aminoacyl-[protein]


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + AH2 + O2 => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + A + 2 H2O


name: ATP + benzoate + H(+) => benzoyl-AMP + diphosphate


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate = CO2 + deoxyviolacein + 2 H2O + NADP(+)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Caenorhabditis elegans)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: (R)-lipoamide + H(+) + NADH => (R)-dihydrolipoamide + NAD(+)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Mus musculus)


name: H(+) + pravastatin => H2O + pravastatin lactone


name: beta-D-fructose 1,6-bisphosphate <=> D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate


name: SIGMAR1 binds dextromethorphan (Homo sapiens)


name: 2'-deoxyinosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine


name: GDIs block activation of RHOB (Mus musculus)


name: USP5 cleaves polyubiquitin (Gallus gallus)


name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA => a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA


name: A + H2O + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] = AH2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3]


name: p-S-TBK1 phosphorylates OPTN (Homo sapiens)


name: H2O + phosphonoacetate = acetate + H(+) + phosphate


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Saccharomyces cerevisiae)


name: PHF8 demethylates MeK21-histone H4 (Canis familiaris)


name: IGF1R phosphorylates SHC1 (Gallus gallus)


name: 9alpha-copalyl diphosphate <=> diphosphate + isopimara-8(14),15-diene


name: Fibrillin microfibril assembly (Canis familiaris)


name: AGRN binds Beta amyloid fibril via GAG chains (Sus scrofa)


name: HSD17B3-like proteins reducde ANDST to TEST (Danio rerio)


name: USP25 deubiquitinates DDX58 (Homo sapiens)


name: D-loop extension by DNA polymerases (Sus scrofa)


name: a disubstituted aliphatic (S)-hydroxynitrile => a ketone + hydrogen cyanide


name: BRCA1 binds phosphorylated RBBP8 (Bos taurus)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Drosophila melanogaster)


name: RUNX3 binds the NOTCH1 coactivator complex (Bos taurus)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Canis familiaris)


name: 3-hydroxyindolin-2-one + NADP(+) => H(+) + isatin + NADPH


name: ATP + glutathione(in) + glycoursodeoxycholate(in) + H2O = ADP + glutathione(out) + glycoursodeoxycholate(out) + H(+) + phosphate


name: ethylenediaminediacetate + 2 FMN + 2 glyoxylate + 3 H(+) + 2 H2O => EDTA + 2 FMNH2 + 2 O2


name: ALDH1A1 oxidises GA to DGA (Homo sapiens)


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Mus musculus)


name: 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 = a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate


name: 3-(methylsulfanyl)propanoyl-CoA + butan-1-ol <=> butyl 3-(methylsulfanyl)propanoate + CoA


name: NTRK3 activates RAS through SHC1 (Homo sapiens)


name: N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol + UMP => trans,octa-cis-decaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine


name: LINC01139 facilitates PTK6 autophosphorylation (Xenopus tropicalis)


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Sus scrofa)


name: 4-hydroxybenzyl alcohol + 2 oxidized [azurin] = 4-hydroxybenzaldehyde + 2 H(+) + 2 reduced [azurin]


name: AKT phosphorylates FOXO3 downstream of ESR1 and EGFR (Caenorhabditis elegans)


name: Phosphorylation of L1 by ERK (Xenopus tropicalis)


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Plasmodium falciparum)


name: NADP(+) + pregnan-21-ol => H(+) + NADPH + pregnan-21-al


name: (R)-lactate(out) + H(+)(out) => (R)-lactate(in) + H(+)(in)


name: 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-tetradecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Mus musculus)


name: 2 Fe(II)-[cytochrome c553] + 2 H(+) + pyruvate => (R)-lactate + 2 Fe(III)-[cytochrome c553]


name: aldehydo-D-galacturonate(out) + H(+)(out) <=> aldehydo-D-galacturonate(in) + H(+)(in)


name: B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda (Bos taurus)


name: [(1->4)-beta-D-glucosyl](n+1) + GDP + H(+) => [(1->4)-beta-D-glucosyl](n) + GDP-alpha-D-glucose


name: SUMOyation of DNMT1 with SUMO1 (Mus musculus)


name: VAV3 is a GEF for Rho/Rac family kinases (Rattus norvegicus)


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Homo sapiens)


name: Auto-ubiquitination of TRAF6 (Canis familiaris)


name: (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2


name: 19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)


name: 14-3-3 dimer binds to phosphorylated YKI (Drosophila melanogaster)


name: SALM2 associate with AMPA and NMDA receptors (Gallus gallus)


name: Activated TP receptor binds G-proten Gq (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = H2O + leukotriene A4


name: a fatty acid + S-adenosyl-L-methionine <=> a fatty acid methyl ester + S-adenosyl-L-homocysteine


name: HDAC8 deacetylates histones (Canis familiaris)


name: dihydroxyacetone phosphate + iminosuccinate => H(+) + 2 H2O + phosphate + quinolinate


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] => 15alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Canis familiaris)


name: p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Caenorhabditis elegans)


name: D-mannose + phosphate => D-mannose 6-phosphate + H2O


name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine (Mus musculus)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Sus scrofa)


name: D-glucose(out) + N(pros)-phospho-L-histidyl-[protein] = D-glucose 6-phosphate(in) + L-histidyl-[protein]


name: H2O + O-phospho-L-seryl-[myosin light chain] => L-seryl-[myosin light chain] + phosphate


name: DCC interacts with DIP13alpha (Canis familiaris)


name: (6S)-5,6,7,8-tetrahydrofolate + N-formimidoyl-L-glutamate => 5-formimidoyltetrahydrofolate + L-glutamate


name: 2-oxoglutarate + L-proline + O2 => cis-4-hydroxy-L-proline + CO2 + succinate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine


name: "phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating)"


name: (2Z,6Z)-farnesyl diphosphate = diphosphate + germacrene C


name: octadecanoyl-CoA + sn-glycerol 3-phosphate => 1-octadecanoyl-sn-glycero-3-phosphate + CoA


name: PGRMC2:Hemes translocate to the nucleus (Sus scrofa)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Rattus norvegicus)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Bos taurus)


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Gallus gallus)


name: ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H2O + L-glutamine = ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + L-glutamate + phosphate


name: "lipid II isoglutaminyl synthase (glutamine-hydrolyzing)"


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose => a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)


name: cholesterol + H(+) + NADPH + O2 => 7-dehydrocholesterol + 2 H2O + NADP(+)


name: Recruitment of CDK11p58 to the centrosomes (Rattus norvegicus)


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Canis familiaris)


name: 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol = 1alpha,2beta,25-trihydroxycholecalciferol + 3-hydroxypropanal


name: sphinga-4E,14Z-dienine-1-phosphate = (2E,12Z)-hexadecadienal + phosphoethanolamine


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Mus musculus)


name: 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine <=> 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate


name: "oxaloacetate decarboxylase (Na(+) extruding)"


name: RHOB GAPs stimulate RHOB GTPase activity (Canis familiaris)


name: NEK6/NEK7 phosphorylates NUP98 (Sus scrofa)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Danio rerio)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Rattus norvegicus)


name: a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Canis familiaris)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Canis familiaris)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Xenopus tropicalis)


name: (R)-normetanephrine + S-adenosyl-L-methionine = (R)-metanephrine + H(+) + S-adenosyl-L-homocysteine


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Bos taurus)


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Sus scrofa)


name: S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity


name: 45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)


name: 7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O => 7,8-dihydroneopterin 3'-phosphate + H(+)


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Sus scrofa)


name: Caspase mediated cleavage of C-IAP1 (Canis familiaris)


name: Calmodulin activates Cam-PDE 1 (Mus musculus)


name: Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Homo sapiens)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Bos taurus)


name: (2E)-13-methyltetradecenoyl-CoA + H(+) + NADPH <=> isopentadecanoyl-CoA + NADP(+)


name: NAD(+) + perillyl alcohol <=> H(+) + NADH + perillyl aldehyde


name: CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol (Homo sapiens)


name: NCOA1 recruits EP300 to TGFA promoter (Mus musculus)


name: CXXC1 and WDR82 bind SET1A complex (Dictyostelium discoideum)


name: all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate = all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + H(+) + UDP


name: 3beta-hydroxy-5alpha-pregnane-20-one + NAD(+) => 5alpha-pregnane-3,20-dione + H(+) + NADH


name: H2O + N(8)-acetylspermidine = acetate + spermidine


name: AcK-NFE2L2- dependent NQO1 gene expression (Homo sapiens)


name: LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Canis familiaris)


name: 5-formimidoyltetrahydrofolate + L-glutamate => (6S)-5,6,7,8-tetrahydrofolate + N-formimidoyl-L-glutamate


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Xenopus tropicalis)


name: SUMOylation of UBE2I with SUMO1 (Mus musculus)


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Canis familiaris)


name: 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H2O <=> chloride + 2 H(+) + maleylacetate


name: Methylation of GMP-cap by RNA Methyltransferase (Canis familiaris)


name: L-threonine + tRNA(Val) => H2O + L-threonyl-tRNA(Val)


name: H2O + L-aspartate 4-semialdehyde + NAD(+) = 2 H(+) + L-aspartate + NADH


name: cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity


name: a D-hexose + an acyl phosphate = a carboxylate + D-hexose phosphate + H(+)


name: a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: MDM2 translocates to the cytosol (Homo sapiens)


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Danio rerio)


name: TRAF1 binds TRAF2 within TNFR1 signaling complex (Bos taurus)


name: Phosphorylated PXN recruits the CRK complex (Mus musculus)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Mus musculus)


name: a ribonucleoside + phosphate => a ribonucleoside 5'-phosphate + H2O


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Plasmodium falciparum)


name: Binding of ADAR1 homodimer to dsRNA duplex (Canis familiaris)


name: P2RY12 binds P2RY12 antagonists (Sus scrofa)


name: Cross-linking of FCGRIIIA with IgG-coated Ag (Sus scrofa)


name: RHOA GAPs stimulate RHOA GTPase activity (Caenorhabditis elegans)


name: a ganglioside Ac-O-7-GD3 + CoA => a ganglioside GD3 + acetyl-CoA


name: Conversion of C4 into C4a and C4b (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha-ol => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha,13alpha-diol


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Sus scrofa)


name: aldehydo-D-glucose 6-phosphate + L-lysyl-[protein] <=> H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein]


name: Liganded Gz-activating GPCR acts as a GEF for Gz (Xenopus tropicalis)


name: IL12RB1:TYK2 binds IL12RB2:JAK2 (Homo sapiens)


name: PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 (Homo sapiens)


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)


name: LONP1 binds mitochondrial inner membrane proteins (Dictyostelium discoideum)


name: a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O => a 2'-deoxyribonucleoside 5'-phosphate + 2 H(+) + 2 phosphate


name: Proteolytic degradation of ubiquitinated-Cdc25A (Homo sapiens)


name: PHF8 demethylates MeK21-histone H4 (Homo sapiens)


name: 2 chloride(in) + H(+)(out) = 2 chloride(out) + H(+)(in)


name: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H(+)


name: (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein] => (7Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: PTK6 phosphorylates STAP2 (Homo sapiens)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Drosophila melanogaster)


name: cholate + NADP(+) <=> 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: E2F1 binds the CDC6 gene promoter (Homo sapiens)


name: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O


name: an anthocyanidin + UDP-alpha-D-galactose => an anthocyanidin 3-O-beta-D-galactoside + UDP


name: ATP(out) + dATP(in) => ATP(in) + dATP(out)


name: MRN complex bound to DNA ends recruits ATM (Bos taurus)


name: HIRA and NPM2 assemble H3.3-containing nucleosomes on paternal DNA (Homo sapiens)


name: 2-phenylacetate + NH4(+) => 2-phenylacetamide + H2O


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA


name: CCNK binds CDK13 (Schizosaccharomyces pombe)


name: AFXBO hydrolyses non-enzymatically to AFBDHD (Homo sapiens)


name: PDCL binds G-protein beta and TRiC/CCT (Xenopus tropicalis)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Xenopus tropicalis)


name: 3,16-dihydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3-hydroxyhexadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Removal of fibrillar collagen C-propeptides (Drosophila melanogaster)


name: P2X7 mediates membrane pores that include pannexin-1 (Homo sapiens)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Danio rerio)


name: GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Bos taurus)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (1S,6S,7R)-sesquipiperitol + diphosphate


name: DOLPP1 dephosphorylates DOLDP to DOLP (Bos taurus)


name: TRAPPC complexes exchange GTP for GDP on RAB1 (Canis familiaris)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Sus scrofa)


name: Indirect recruitment of GAB2 to p-KIT (Mus musculus)


name: anthocyanin A10 + malonyl-CoA = anthocyanin A11 + CoA


name: O-atom dealkylation of dextromethorphan (Homo sapiens)


name: 4alpha-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 4alpha-hydroxymethylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: L-leucine(out) + L-ornithine(in) + Na(+)(out) => L-leucine(in) + L-ornithine(out) + Na(+)(in)


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Caenorhabditis elegans)


name: nsp3 binds to PLpro inhibitors (Homo sapiens)


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Caenorhabditis elegans)


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Rattus norvegicus)


name: 2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine => 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate


name: Oxidative damage to the AP site (Canis familiaris)


name: HMGCR dimer binds statins (Xenopus tropicalis)


name: Phosphorylation of PLC-gamma by p-BTK/p-SYK (Homo sapiens)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Xenopus tropicalis)


name: 2 Fe(III)-[cytochrome c] + 2 thiosulfate => 2 Fe(II)-[cytochrome c] + 2 H(+) + tetrathionate


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Bos taurus)


name: acrolein + H2O + O2 = acrylate + H(+) + H2O2


name: (R)-mevaldate + H(+) + NADPH => (R)-mevalonate + NADP(+)


name: L-xylopyranose(in) + 2 Na(+)(in) => L-xylopyranose(out) + 2 Na(+)(out)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Rattus norvegicus)


name: butanal + H(+) + NADPH => butan-1-ol + NADP(+)


name: PDCL releases folded G-beta from TRiC/CCT (Rattus norvegicus)


name: mTORC1 binds RHEB:GTP (Saccharomyces cerevisiae)


name: acetyl-CoA + D-glutamate <=> CoA + H(+) + N-acetyl-D-glutamate


name: H2O + L-alanyl-L-aspartate = L-alanine + L-aspartate


name: ERBB4s80:STAT5A complex translocates to the nucleus (Danio rerio)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+) + NADPH = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + NADP(+)


name: PIP3 recruits PDPK1 to the membrane (Danio rerio)


name: 16 ATP + 16 H2O + N2 + 8 reduced [2Fe-2S]-[ferredoxin] => 16 ADP + 6 H(+) + H2 + 2 NH4(+) + 8 oxidized [2Fe-2S]-[ferredoxin] + 16 phosphate


name: Passive I- efflux mediated by SLC5A8 (Danio rerio)


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Drosophila melanogaster)


name: 3-oxopropanoate + H(+) <=> acetaldehyde + CO2


name: KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Homo sapiens)


name: H(+)(out) + L-tyrosylglycine(out) <=> H(+)(in) + L-tyrosylglycine(in)


name: GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Drosophila melanogaster)


name: MATS is phosphorylated by HPO dimer and binds to phosphorylated WTS (Drosophila melanogaster)


name: Recruitment of Src and Fyn to DCC:FADK1 (Homo sapiens)


name: miR-21 RISC binds DNMT1 mRNA (Homo sapiens)


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Caenorhabditis elegans)


name: 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 23S,25-dihydroxy-24-oxocholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: Phosphorylation of APS (Rattus norvegicus)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Saccharomyces cerevisiae)


name: 5-hydroxyoctan-4-one + H(+) + NADH + NH4(+) => 5-hydroxyoctan-4-amine + H2O + NAD(+)


name: aminodiacetate + FMN + glyoxylate + H2O => FMNH2 + nitrilotriacetate + O2


name: glycyl-L-asparagine + H2O => glycine + L-asparagine


name: 2 AH2 + all-trans-beta-carotene + 2 O2 <=> 2 A + echinenone + 3 H2O


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: Recognition and Binding of Core Promoter Elements by TFIID (Xenopus tropicalis)


name: AH2 + formaldehyde + L-glutamate => A + H2O + N-methyl-L-glutamate


name: p-S115 MAPKAPK5 translocates to the cytosol (Plasmodium falciparum)


name: GUSB tetramer hydrolyses CS/HS precursor (Sus scrofa)


name: apo-[methylmalonyl-CoA:pyruvate carboxytransferase] + ATP + biotin => AMP + diphosphate + H(+) + holo-[methylmalonyl-CoA:pyruvate carboxytransferase]


name: PDE4A,C,D hydrolyse cAMP (Xenopus tropicalis)


name: H(+) + N(1)-[(S)-3-amino-3-carboxypropyl]agmatine => CO2 + N(1)-(3-aminopropyl)agmatine


name: [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n) + n ATP + n D-aspartate = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + n ADP + n H(+) + n phosphate


name: S-adenosyl-L-homocysteine + trimethylsulfonium => dimethyl sulfide + S-adenosyl-L-methionine


name: SUMOylation of TOPORS with SUMO1 (Sus scrofa)


name: 4-hydroxybenzoate(in) + H(+)(out) = 4-hydroxybenzoate(out) + H(+)(in)


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: L-alanine + phosphonoacetaldehyde => (2-aminoethyl)phosphonate + pyruvate


name: 9 CO2 + 9 CoA + dihydro-ML-236C-[compactin nonaketide synthase] + 6 H2O + 11 NADP(+) => 20 H(+) + holo-[compactin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH


name: L-arginine(in) + L-phenylalanine(out) => L-arginine(out) + L-phenylalanine(in)


name: RNASEL cleaves cellular ssRNA (Rattus norvegicus)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Bos taurus)


name: asperlicin C + H(+) + NADPH + O2 <=> asperlicin E + H2O + NADP(+)


name: 2 H(+) + S-adenosyl-L-homocysteine + vobasine => perivine + S-adenosyl-L-methionine


name: SCF-FBXL18 ubiquitinates FBXL7 (Bos taurus)


name: BDNF-bound NTRK2 dimerizes (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] = 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Danio rerio)


name: D-apionolactone + H(+) + NADH => D-apiofuranose + NAD(+)


name: 4beta-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-4beta,26-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: HIPK2 phosphorylates RUNX1 and EP300 (Mus musculus)


name: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: Recruitment of Telomerase RNP to the Telomeric Chromosome End (Mus musculus)


name: D-arabinose 5-phosphate + H2O + phosphoenolpyruvate <=> 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Mus musculus)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Caenorhabditis elegans)


name: H(+)(in) + L-alanyl-L-prolylglycine(in) => H(+)(out) + L-alanyl-L-prolylglycine(out)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein] => acetyl-CoA + N-terminal L-methionyl-L-leucyl-[protein]


name: thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Danio rerio)


name: RHOQ binds GOPC:CFTR (Rattus norvegicus)


name: AP-2 directly binds some endocytic cargo (Schizosaccharomyces pombe)


name: TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Sus scrofa)


name: 2-hydroxyoctanoate + O2 = 2-oxooctanoate + H2O2


name: ATP binds G-protein beta associated TRiC/CCT (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O => (9Z)-octadecenoate + H(+) + sn-glycero-3-phosphoethanolamine


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP


name: L-rhamnofuranose + NADP(+) => H(+) + L-rhamnono-1,4-lactone + NADPH


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+) => 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADPH


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Gallus gallus)


name: 2-hydroxybenzoyl-5'-AMP + holo-[ACP] <=> AMP + H(+) + salicyl-[ACP]


name: (2E)-2-butenoate + ATP + holo-[ACP] => (2E)-butenoyl-[ACP] + AMP + diphosphate


name: Release of Cytochrome c from mitochondria (Rattus norvegicus)


name: Binding of IRS to insulin receptor (Homo sapiens)


name: PCK2 phosphorylates OA to yield PEP (Canis familiaris)


name: atROL binds RBP1 to form RBP1:atROL (Bos taurus)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + chloride + H(+) => (3R,4S,5S,6R)-pentachlorocyclohexene


name: S-adenosyl-L-methionine + xanthosine = 7-methylxanthosine + S-adenosyl-L-homocysteine


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Caenorhabditis elegans)


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate <=> 1,3-di-(9Z)-hexadecenoylglycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: glycolate + NAD(+) <=> glyoxylate + H(+) + NADH


name: phycocyanobilin-L-cysteinyl(84)-[allophycocyanin alpha-subunit] = (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[allophycocyanin alpha-subunit]


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Mus musculus)


name: (9Z)-hexadecenoyl-CoA + [Wnt protein]-L-serine = [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + CoA


name: "[Wnt protein] O-palmitoleoyl transferase"


name: H2O + L-tryptophan + NAD(+) <=> H(+) + indole-3-pyruvate + NADH + NH4(+)


name: UIMC1 and FAM175A bind DNA DSBs (Sus scrofa)


name: melibiose(out) + Na(+)(out) => melibiose(in) + Na(+)(in)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Bos taurus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: AH2 + N-acyl-15-methylhexadecasphinganine + O2 => A + 2 H2O + N-acyl-15-methylhexadecasphing-4-enine


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Sus scrofa)


name: a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + O2 => a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + H2O + NAD(+)


name: hexanoyl-CoA + tyramine = CoA + H(+) + N-hexanoyltyramine


name: 19 H(+) + holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine = 9 CO2 + 9 CoA + dihydromonacolin L-[lovastatin nonaketide synthase] + 6 H2O + 11 NADP(+) + S-adenosyl-L-homocysteine


name: CRK,CRKL recruits RAC1 GEF to activated MET (Xenopus tropicalis)


name: Activation of RAC1 by the PXN:CRK complex (Rattus norvegicus)


name: MITF-M dimer and TFAP2A bind the IRF4 gene (Homo sapiens)


name: a D-alpha-amino acid + O2 => a 2-iminocarboxylate + H2O2


name: CoA + H(+) + N-tetradecanoyl-3-oxosphinganine => 3-oxosphinganine + tetradecanoyl-CoA


name: Nuclear DUSPs dephosphorylate MAPKs (Canis familiaris)


name: dAMP + 2 H(+) + 2 phosphate => dATP + 2 H2O


name: ARL3:GTP binds the UNC119B complex (Bos taurus)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Sus scrofa)


name: PINK1 is autophosphorylated (Canis familiaris)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Mus musculus)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Danio rerio)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Plasmodium falciparum)


name: L-alanine(in) + L-valine(out) => L-alanine(out) + L-valine(in)


name: Release of the RNP into the host cell nucleus (Homo sapiens)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Caenorhabditis elegans)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Canis familiaris)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Bos taurus)


name: AMP + diphosphate + pentadecanoyl-CoA => ATP + CoA + pentadecanoate


name: Trafficking of GluR1-containing  AMPA receptors (Rattus norvegicus)


name: NTPDase6 hydrolyzes nucleoside diphosphates (Schizosaccharomyces pombe)


name: 1-O-hexadecyl-sn-glycerol + acetate + H(+) => 1-O-hexadecyl-2-acetyl-sn-glycerol + H2O


name: ADP + D-alanyl-D-alanine + H(+) + phosphate => ATP + 2 D-alanine


name: Dephosphorylation of inactive SRC by PTPB1 (Mus musculus)


name: corticosterone + NADP(+) <=> 11-dehydrocorticosterone + H(+) + NADPH


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Mus musculus)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Xenopus tropicalis)


name: (2E)-geranyl diphosphate + olivetolate = cannabigerolate + diphosphate


name: 2-dehydro-L-idonate + NADP(+) => 2,5-didehydro-D-gluconate + H(+) + NADPH


name: LGI3 binds ADAM22,23,synatxin1 (Canis familiaris)


name: GUK1 phosphorylates 6TGMP to 6TGDP (Danio rerio)


name: a fatty acid + L-asparagine => an N-(fatty acyl)-L-asparagine + H2O


name: Proteasome mediated degradation of COP1 (Canis familiaris)


name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)


name: EGF-domain serine glucosyltransferase activity


name: RNA Pol II initiates transcription from damaged DNA template (Rattus norvegicus)


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Rattus norvegicus)


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Canis familiaris)


name: Formation of Cyclin A:Cdk2 complexes (Bos taurus)


name: a sterol 3-beta-D-glucoside + H(+) + UDP => a sterol + UDP-alpha-D-glucose


name: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)


name: (S)-miconazole(in) + ATP + H2O = (S)-miconazole(out) + ADP + H(+) + phosphate


name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)


name: Ubiquitination of stimulated EGFR (CBL) (Mus musculus)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Schizosaccharomyces pombe)


name: acetyl-CoA + L-tryptophan + malonyl-CoA <=> CO2 + 2 CoA + cyclo-acetoacetyl-L-tryptophan + H2O


name: DAG stimulates protein kinase C-delta (Gallus gallus)


name: [DsbA protein]-dithiol + [DsbB protein]-disulfide => [DsbA protein]-disulfide + [DsbB protein]-dithiol


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Rattus norvegicus)


name: 3-dehydro-4-O-phospho-D-erythronate + ADP + H(+) => 3-dehydro-D-erythronate + ATP


name: AOC1 deaminates Hist (Xenopus tropicalis)


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-2-acetyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: 2-hydroxy-3-oxoadipate + CO2 => 2-oxoglutarate + glyoxylate + H(+)


name: BCDX2 complex stabilizes RAD51 filament (Canis familiaris)


name: 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde => acetoin + aldehydo-D-ribose 5-phosphate


name: 2-oxoglutarate + hexanoyl-CoA + O2 => 2-hydroxyhexanoyl-CoA + CO2 + succinate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ADP + H(+) + phosphate


name: Phosphorylation of SHC by SYK kinase (Mus musculus)


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Xenopus tropicalis)


name: (4Z,15Z)-bilirubin IXalpha + bilirubin IXalpha bis-beta-D-glucuronoside => 2 (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside


name: ADP + H(+) + kanamycin 3'-phosphate => ATP + kanamycin A


name: L-isoleucine transmembrane transporter activity


name: MTORC1 dissociates from ULK complex (Bos taurus)


name: 1,2-dichloroethene reductive dehalogenase activity


name: fenbendazole + O2 + reduced [NADPH--hemoprotein reductase] = 4'-hydroxyfenbendazole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CTP(out) + ITP(in) => CTP(in) + ITP(out)


name: GTP => cyclic pyranopterin phosphate + diphosphate


name: 2-oxoglutarate + a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in U6 snRNA + O2 => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in U6 snRNA + CO2 + formaldehyde + succinate


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Bos taurus)


name: (S)-norcodamine + H(+) + S-adenosyl-L-homocysteine => (S)-norreticuline + S-adenosyl-L-methionine


name: NH4(+) + xanthosine => guanosine + H(+) + H2O


name: a 1,2-diacylglycerol + a fatty acyl-[ACP] = a triacylglycerol + holo-[ACP]


name: Translocation of Cdc25 to the nucleus (Caenorhabditis elegans)


name: L-glutamate(in) + L-thyroxine(out) <=> L-glutamate(out) + L-thyroxine(in)


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Sus scrofa)


name: an (11Z,14Z)-icosadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: T2Rs bind bitter-tasting compounds (Danio rerio)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Xenopus tropicalis)


name: [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + H(+) + NADPH + O2 => [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B + H2O + NADP(+)


name: phycocyanobilin-L-cysteinyl(84)-[phycoerythrocyanin beta-subunit] = (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[phycoerythrocyanin beta-subunit]


name: IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Bos taurus)


name: JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Rattus norvegicus)


name: DNA-PKcs autophosphorylates (Rattus norvegicus)


name: 7-dehydrocholesterol + 2 H2O + NADP(+) => cholesterol + H(+) + NADPH + O2


name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Bos taurus)


name: clavaminate + CO2 + H2O + succinate => 2-oxoglutarate + dihydroclavaminate + O2


name: 2-epi-5-epi-valiolone + ATP = 2-epi-5-epi-valiolone 7-phosphate + ADP + H(+)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Schizosaccharomyces pombe)


name: 13-deoxycarminomycin + H(+) + NADPH + O2 = 13-dihydrocarminomycin + H2O + NADP(+)


name: RIPK3 is cleaved by CASP8 (Mus musculus)


name: atRAL is reduced to atROL (Rattus norvegicus)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Xenopus tropicalis)


name: DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)


name: KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Saccharomyces cerevisiae)


name: APC/C:Cdh1-mediated degradation of Skp2 (Rattus norvegicus)


name: asperlicin C + H(+) + NADH + O2 => asperlicin E + H2O + NAD(+)


name: laricitrin + S-adenosyl-L-methionine = 3,3'-O-dimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: fatty acid in-chain hydroxylase activity


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Drosophila melanogaster)


name: Glucagon-like receptor 2 binds GLP2 (Sus scrofa)


name: SMAD1:SMAD4 trimer binds ZNF423 (Homo sapiens)


name: myo-inositol + S-adenosyl-L-methionine <=> 1D-1-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: heptan-2-one + hydrogen cyanide => (2S)-2-hydroxy-2-methylheptanenitrile


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Canis familiaris)


name: carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L-citrulline + phosphate


name: 2 sucrose <=> 6-kestotriose + beta-D-glucose


name: Syndecan-1 binds Integrin alphaVBeta5 (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + glycodeoxycholate <=> 3alpha-sulfoglycodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: ATP + H2O + selenite(out) = ADP + H(+) + phosphate + selenite(in)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Caenorhabditis elegans)


name: MAPK1-dependent phosphorylation of MITF-M (Rattus norvegicus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out)


name: N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + O2 => H2O + N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline


name: TNF-α:TNFR1 binds DENN/MADD (Homo sapiens)


name: 3-hydroxyoctadecanoyl-CoA + NADP(+) => 3-oxooctadecanoyl-CoA + H(+) + NADPH


name: Keratin type I binds keratin type II (Rattus norvegicus)


name: beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (5R,6S)-5,6-epoxi-beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H2O + NAD(+) + trimethylamine <=> 2 H(+) + NADH + trimethylamine N-oxide


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Drosophila melanogaster)


name: H2O + NADP(+) + nitrite <=> H(+) + NADPH + nitrate


name: [cis-1,4-isoprene](n) + O2 <=> (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal + cis-1,4-isoprene(n-3)


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Gallus gallus)


name: mating type region replication fork barrier binding


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Bos taurus)


name: 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(+) <=> 15-oxoprostaglandin E2 + H(+) + NADH


name: a (3R)-hydroxyacyl-[ACP] <=> a (2E)-enoyl-[ACP] + H2O


name: (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O <=> (9Z)-octadecenoate + (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + H(+)


name: a bacteriochlorophyllide d + S-adenosyl-L-methionine <=> a bacteriochlorophyllide c + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Xenopus tropicalis)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Drosophila melanogaster)


name: a ganglioside Ac-O-8-GD3 = a ganglioside Ac-O-9-GD3


name: Conversion of Glycerol to Glycerol-3-phosphate (Xenopus tropicalis)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Dictyostelium discoideum)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Sus scrofa)


name: a 1,2-diacyl-sn-glycerol + a glycerophospholipid => a monoacylglycerophospholipid + a triacyl-sn-glycerol


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Gallus gallus)


name: (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + CO2 + succinate => 2-oxoglutarate + L-asparaginyl-[ankyrin-repeat domain protein] + O2


name: A + androst-4-ene-3,17-dione <=> AH2 + androsta-1,4-diene-3,17-dione


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-glycerol <=> 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n CMP + n H(+)


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Homo sapiens)


name: 2 a 1-acyl-sn-glycero-3-phosphocholine <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: A + D-serine + H2O <=> 3-hydroxypyruvate + AH2 + NH4(+)


name: BPI binds LPS on the bacterial surface (Xenopus tropicalis)


name: butanoate + cyclohexane-1-carbonyl-CoA => butanoyl-CoA + cyclohexane-1-carboxylate


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Homo sapiens)


name: DSPG and CSPG translocate to the lysosome for degradation (Danio rerio)


name: H2O + N-terminal N-formyl-L-methionyl-[peptide] <=> formate + N-terminal L-methionyl-[peptide]


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Bos taurus)


name: Activated FGFR4 phosphorylates FRS3 (Danio rerio)


name: ent-kaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] = ent-7alpha-hydroxykaur-16-en-19-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + H2O => AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + diphosphate + H(+) + phosphate


name: [protein]-dithiol + [thioredoxin]-disulfide => [protein]-disulfide + [thioredoxin]-dithiol


name: a ubiquinone + ethanol => a ubiquinol + acetaldehyde


name: 4-hydroxybenzoate + pyruvate => chorismate


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Mus musculus)


name: 2 H(+)(in) + L-alanyl-L-alanine(in) => 2 H(+)(out) + L-alanyl-L-alanine(out)


name: diphosphate + P(1),P(4)-bis(5'-adenosyl) tetraphosphate => 2 ATP + H(+)


name: KAT5 HAT complex acetylates TCF4 gene at histone H4 (Homo sapiens)


name: CoA(out) + NAD(+)(in) => CoA(in) + NAD(+)(out)


name: Hh-Npp binds GAS1 and PTCH (Mus musculus)


name: A + H2O + quinoline <=> AH2 + quinolin-2(1H)-one


name: L-alanine + oxomalonate <=> aminomalonate + pyruvate


name: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O


name: ITPA hydrolyses dITP to dIMP (Canis familiaris)


name: SOCS3 binds activated PTK6 (Danio rerio)


name: 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA => 3-methylundecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: ETA is phosphorylated to PETA by CHK/ETNK (Schizosaccharomyces pombe)


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)


name: coelenterazine h + O2 => coelenterazine h dioxetanone


name: AMP + H2O => IMP + NH4+ (AMPD) (Schizosaccharomyces pombe)


name: Spherical HDL binds C and E apolipoproteins (Canis familiaris)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Xenopus tropicalis)


name: ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2 = ergosterol + 2 H2O + NADP(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O <=> (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + CoA + H(+)


name: Release of Cytochrome c from mitochondria (Xenopus tropicalis)


name: H(+) + N,N-dihydroxy-L-tyrosine = (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O


name: a globoside Gb4Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside Forssman (d18:1(4E)) + H(+) + UDP


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H2O = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + phosphate


name: glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Gallus gallus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine => 2 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Sus scrofa)


name: (2R,3S)-iso(homo)3citrate + NAD(+) = 2-oxosuberate + CO2 + NADH


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Caenorhabditis elegans)


name: an acyl-CoA + pseudotropine => CoA + H(+) + O-acylpseudotropine


name: lactose + H2O => D-glucose + D-galactose (Sus scrofa)


name: L-phenylalanyl-L-methionine + L-tyrosylglycylglycine => H2O + Met-enkephalin


name: cordycepin + H(+) + H2O <=> 3'-deoxyinosine + NH4(+)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione <=> (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: beta-nicotinamide D-ribonucleotide + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide


name: beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + UDP-alpha-D-galactose = a neolactoside nLc4Cer + H(+) + UDP


name: ERBB4 forms heterodimers with ERBB3 (Bos taurus)


name: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate


name: Cis-Heterodimerization of nephrin and KIRREL (Sus scrofa)


name: dibenzofuran + H(+) + NADH + O2 <=> biphenyl-2,2',3-triol + NAD(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 11-hydroxysugiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 11,20-dihydroxysugiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cya and lef bind to pagA(197-794):ANTXR2 oligomer (Homo sapiens)


name: 5-dehydro-D-gluconate + H(+) + NADPH => D-gluconate + NADP(+)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Gallus gallus)


name: MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Mus musculus)


name: an adenosine in mRNA + S-adenosyl-L-methionine <=> an N(1)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: Correctly folded glycoproteins translocate to the Golgi (Homo sapiens)


name: (9Z)-hexadecenoyl-CoA + AMP + diphosphate => (9Z)-hexadecenoate + ATP + CoA


name: ADP(out) + H(+)(out) + phosphate(in) = ADP(in) + H(+)(in) + phosphate(out)


name: DVL1 is ubiquitinated by HECW1 (Drosophila melanogaster)


name: The receptor:G-protein complex dissociates (Mus musculus)


name: Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (Drosophila melanogaster)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)


name: Estrogen-responsive EBAG9 gene expression (Homo sapiens)


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Dictyostelium discoideum)


name: RAC1 GDIs block activation of RAC1 (Dictyostelium discoideum)


name: BRCA1 binds phosphorylated RBBP8 (Rattus norvegicus)


name: 2-oxoglutarate + deacetoxyvindoline + O2 => 4-O-deacetylvindoline + CO2 + succinate


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Drosophila melanogaster)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Bos taurus)


name: D-glucose + lithocholate => beta-D-glucosyl-(1->3)-O-lithocholate + H2O


name: 3-oxopentanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxypentanoyl-[ACP] + NADP(+)


name: MERTK receptor binds ligands (Gas6 or Protein S) (Bos taurus)


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Rattus norvegicus)


name: POLI incorporates dNMP opposite to damaged DNA base (Saccharomyces cerevisiae)


name: L-arginyl-[protein] + L-cysteinyl-[protein] + methylglyoxal => H(+) + 2 H2O + N(5)-[4-(S-L-cysteinyl-[protein])-5-methyl-1H-imidazol-2-yl]-L-ornithinyl-[protein]


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Danio rerio)


name: a dicarboxylate(in) + prostaglandin F2alpha(out) => a dicarboxylate(out) + prostaglandin F2alpha(in)


name: cyanate + 2 Fe(II)-[cytochrome c] + 2 H(+) + sulfur => 2 Fe(III)-[cytochrome c] + H2O + thiocyanate


name: Aquaporins passively transport glycerol out of cells (Saccharomyces cerevisiae)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Sus scrofa)


name: nitrite efflux transmembrane transporter activity


name: S2P hydrolyzes SREBP1A,1C,2 (Canis familiaris)


name: VCAM1 binds Integrin alpha4beta1 (Danio rerio)


name: cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine <=> H(+) + N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine


name: H2O + sn-glycerol 3-phosphocholine = choline + H(+) + sn-glycerol 3-phosphate


name: H2O + L-serine-phosphoethanolamine = H(+) + L-serine + phosphoethanolamine


name: PEX7 binds cargo proteins containing PTS2 (Bos taurus)


name: Translocation of activated BAD protein to mitochondria (Canis familiaris)


name: chenodeoxycholate + NAD(+) => 3-oxochenodeoxycholate + H(+) + NADH


name: Clustering of Integrin alphaIIb beta3 complexes (Danio rerio)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Canis familiaris)


name: 1-O-(1Z)-hexadecenyl-2 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+)


name: 15-methylhexadecasphing-4-enine 1-phosphate = (2E)-13-methyltetradecenal + phosphoethanolamine


name: 3-oxosphinganine + dodecanoyl-CoA <=> CoA + H(+) + N-dodecanoyl-3-oxosphinganine


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine


name: a 5'-end ribonucleotide-tRNA(His) + ATP + H(+) => a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate


name: NADP(+) + prephenate <=> 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH


name: (E)-beta-farnesene + diphosphate => (2E,6E)-farnesyl diphosphate


name: RHOA:GTP translocates to the ER membrane (Mus musculus)


name: H(+) + hypotaurine + NADPH + O2 <=> H2O + NADP(+) + taurine


name: 14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD(+) <=> 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + H(+) + NADH


name: Ubiquitination of stimulated EGFR (CBL) (Danio rerio)


name: CREB3L3 translocates from the cytosol to the nucleus (Canis familiaris)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Bos taurus)


name: 2 H(+) + N-(carboxyaminomethyl)urea = CO2 + N-(aminomethyl)urea


name: 4beta-methylzymosterol-4alpha-carbaldehyde + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4beta-methylzymosterol-4alpha-carboxylate + 2 Fe(III)-[cytochrome b5] + H2O


name: Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Sus scrofa)


name: emodin + S-adenosyl-L-methionine = physcion + S-adenosyl-L-homocysteine


name: ADRM1:26S proteaseome binds UCHL5 (Dictyostelium discoideum)


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Caenorhabditis elegans)


name: Nuclear translocation of catalytic domain of Mst3 (Sus scrofa)


name: 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate => 7,8-dihydroneopterin 3'-phosphate + H2O


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-sn-glycero-3-phosphocholine


name: CoA + tetradecanoate phytyl ester => phytol + tetradecanoyl-CoA


name: AFG3L2 degrades mitochondrial matrix proteins (Plasmodium falciparum)


name: CNIH2,3 bind GRIA1 (Drosophila melanogaster)


name: p-S303,307-HSF1 binds YWHAE (14-3-3) (Saccharomyces cerevisiae)


name: AMP(in) + CMP-N-acetyl-beta-neuraminate(out) => AMP(out) + CMP-N-acetyl-beta-neuraminate(in)


name: holo-[polyketide synthase] + prefumagillin => dodecapentaneoyl-[polyketide synthase] + fumagillol


name: H2O + neurotensin => L-isoleucyl-L-leucine + neurotensin(1-11)


name: PEX3:PEX19:class I PMP dissociates (Homo sapiens)


name: Synthesis of PIP3 from PIP2 by PI3K (Caenorhabditis elegans)


name: a globoside Gb3Cer (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + D-galactose


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Canis familiaris)


name: REV1 inserts dCMP opposite to AP sites in DNA (Bos taurus)


name: Phosphorylation (Ser5) of RNA pol II CTD (Danio rerio)


name: 4-chlorophenylacetate + NADH + O2 <=> 3,4-dihydroxyphenylacetate + chloride + NAD(+)


name: butyl 2-(methylsulfanyl)acetate + CoA => 2-(methylsulfanyl)acetyl-CoA + butan-1-ol


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Xenopus tropicalis)


name: acetone oxime + pyruvate => 2-(hydroxyimino)propanoate + acetone


name: Activation of Protein Kinase C novel isoforms (Dictyostelium discoideum)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Sus scrofa)


name: Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA (Homo sapiens)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Sus scrofa)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Rattus norvegicus)


name: CDC42:GTP binds CBL:Beta-Pix (Sus scrofa)


name: Phosphorylation of SLP-76 by p-SYK (Bos taurus)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Caenorhabditis elegans)


name: POM121 binds the Nup107-Nup160 complex (Mus musculus)


name: FadD26, FadD28 transfer adenylyl group to a LCFA (Mycobacterium tuberculosis)


name: (1S)-1,25-dihydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (1S)-1,23,25-trihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin]


name: NADSYN1 hexamer amidates NAAD to NAD+ (Rattus norvegicus)


name: CYP3A4 binds CYP3A4 inhibitors (Danio rerio)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Gallus gallus)


name: nicotinate(in) + urate(out) <=> nicotinate(out) + urate(in)


name: Interaction of DAP12 and MDL-1 (Sus scrofa)


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen


name: BTLA interacts with HVEM (Canis familiaris)


name: MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Sus scrofa)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Mus musculus)


name: 2 H(+) + L-aspartate + 3 NADPH + 3 O2 <=> 2-nitrobutanedioate + 4 H2O + 3 NADP(+)


name: ABHD4 hydrolyses NAPE (Saccharomyces cerevisiae)


name: Assembly of IFT A complex (Canis familiaris)


name: H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] => L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate


name: dAMP + H2O <=> 2'-deoxyadenosine + phosphate


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate => 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)


name: p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Canis familiaris)


name: ACY1:Zn2+ dimer hydrolyses mercapturic acids (Drosophila melanogaster)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Xenopus tropicalis)


name: 2-hydroxybenzoyl-CoA + AMP + diphosphate => ATP + CoA + salicylate


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Canis familiaris)


name: Phosphorylation of CI by CKIalphaepsilon (CKIalpha/DCO) (Drosophila melanogaster)


name: 14-3-3 zeta binding allows recruitment of PI3K (Homo sapiens)


name: XPO1 binds the beta-catenin:CBY complex (Homo sapiens)


name: Degradation of SMAD2/3:SMAD4 complex (Caenorhabditis elegans)


name: [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + ADP => [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ATP


name: kaempferide + S-adenosyl-L-methionine <=> 3,4'-O-dimethylkaempferol + H(+) + S-adenosyl-L-homocysteine


name: 2 H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine => L-arginyl-[protein] + 2 S-adenosyl-L-methionine


name: GTP loading by Rheb (Drosophila melanogaster)


name: Galpha-olf:GTP binds to adenylate cyclase and activates it (Dictyostelium discoideum)


name: ABCB1 transports xenobiotics out of the cell (Sus scrofa)


name: (2E,5S,6E,8E,10E)-1-aminododeca-2,6,8,10-tetraen-5-ol + pyruvate <=> (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + L-alanine


name: aurachin C + H(+) + NADPH + O2 => aurachin C epoxide + H2O + NADP(+)


name: cholesterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (16S,22S)-dihydroxycholesterol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex (Homo sapiens)


name: Edited Kainate Receptor binds glutamate (Mus musculus)


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: CLDN5 (Claudin-5) gene expression is stimulated by RUNX1 (Homo sapiens)


name: p-Y-STATs dissociate (Rattus norvegicus)


name: ATP + GTP => 3',3'-cGAMP + 2 diphosphate


name: Passive I- efflux mediated by SLC5A8 (Bos taurus)


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Drosophila melanogaster)


name: Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Gallus gallus)


name: MAOB:FAD oxidatively deaminates TYR (Mus musculus)


name: H(+)(in) + L-cysteine(out) + Na(+)(out) = H(+)(out) + L-cysteine(in) + Na(+)(in)


name: GNRHR binds GNRHR peptide antagonists (Sus scrofa)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Rattus norvegicus)


name: trimethylamine-N-oxide reductase (cytochrome c) activity


name: Enzyme-bound ATP is released (Bos taurus)


name: p-S363,S380,T573 RS6K translocates to the nucleus (Sus scrofa)


name: GALNT3 transfers GalNAc to FGF23 (Rattus norvegicus)


name: 5-hydroxythiophene-2-carbonyl-CoA + A + H(+) + H2O => AH2 + O2 + thiophene-2-carbonyl-CoA


name: ATP + D-ribose 5-phosphate => ADP + alpha-D-ribose 1,5-bisphosphate + H(+)


name: PAQR3 binds inactive RAFs (Homo sapiens)


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Rattus norvegicus)


name: (omega-1)-methyl-(3R)-hydroxy-fatty acyl-CoA + NADP(+) => (omega-1)-methyl-3-oxo-fatty acyl-CoA + H(+) + NADPH


name: 3-oxohexadecanoyl-[ACP] + CO2 + holo-[ACP] => H(+) + malonyl-[ACP] + tetradecanoyl-[ACP]


name: Dopa is oxidized to dopaquinone by TYR (Mus musculus)


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Danio rerio)


name: dodecanedioyl-CoA + O2 => (2E)-dodecenedioyl-CoA + H2O2


name: S-adenosyl-L-methionine + scutellarein 4'-methyl ether <=> ladanein + S-adenosyl-L-homocysteine


name: beta-nicotinamide D-riboside(in) => beta-nicotinamide D-riboside(out)


name: H2O + O-phospho-L-serine = L-serine + phosphate


name: chorismate + H2O + 2 L-glutamine <=> 4-amino-4-deoxychorismate + 2 L-glutamate + NH4(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A = 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: GLI proteins bind CDC73 (Xenopus tropicalis)


name: 3-oxochenodeoxycholate + H(+) + NADH = isochenodeoxycholate + NAD(+)


name: 2 hydrogencarbonate(in) + oxalate(out) => 2 hydrogencarbonate(out) + oxalate(in)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Dictyostelium discoideum)


name: Melanin-concentrating hormone receptors bind MCH (Canis familiaris)


name: HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (Bos taurus)


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Rattus norvegicus)


name: H2O + lactose 6-phosphate <=> beta-D-glucose + D-galactose 6-phosphate


name: (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O


name: MTMR12 binds MTMR2 (Drosophila melanogaster)


name: SLCO2B1 has a narrow substrate specificity (Drosophila melanogaster)


name: (2S)-methylpentadecanoyl-CoA + O2 = 2-methyl-(2E)-pentadecenoyl-CoA + H2O2


name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity


name: H2O + N-(dodecanoyl)-sphinganine => dodecanoate + sphinganine


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: ST3GAL5 transfers NeuNAc to ceramides (Canis familiaris)


name: HP1 alpha binds Histone H3K9(me)3 (Gallus gallus)


name: 3,4-dihydrocoumarin + H2O <=> 3-(2-hydroxyphenyl)propanoate + H(+)


name: TIMM22 inserts proteins into inner membrane (Homo sapiens)


name: asc-omegaC5-CoA + O2 = asc-omegaDeltaC5-CoA + H2O2


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] => 1-[11-hydroxy-(9Z)-octadecenoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTEN dephosphorylates PIP3 (Homo sapiens)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Bos taurus)


name: deoxyviolaceinate + H(+) + O2 => CO2 + deoxyviolacein + H2O


name: Multiubiquitination of APC/C-associated Cdh1 (Canis familiaris)


name: 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Bos taurus)


name: Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA (Sus scrofa)


name: p-S158,221-HuR binds mRNA (Xenopus tropicalis)


name: [(1->4)-beta-D-mannosyl](n) + phosphate = [(1->4)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate


name: acetyl-CoA + H2O + oxaloacetate => citrate + CoA + H(+)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methenyltetrahydrofolate + NADPH


name: 2 H(+) + hexadecanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (4Z)-hexadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Caspase-mediated cleavage of PKC theta (Bos taurus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-hexacosanoylsphinganine + O2 <=> 2 Fe(III)-[cytochrome b5] + H2O + N-hexacosanoyl-(4R)-hydroxysphinganine


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Homo sapiens)


name: 6-carboxyhexanoyl-[ACP] methyl ester + H2O = 6-carboxyhexanoyl-[ACP] + H(+) + methanol


name: "pimeloyl-[acyl-carrier protein] methyl ester esterase"


name: dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2


name: Binding of cAMP to HCN channels (Gallus gallus)


name: (R)-carnitine(out) + glutarate(in) = (R)-carnitine(in) + glutarate(out)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O => a 5'-end phospho-guanosine in mRNA + 2 H(+) + N(7)-methyl-GDP


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Xenopus tropicalis)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Xenopus tropicalis)


name: Defective IRAK4 does not form a complex with MyD88 within the TLR5 complex (Homo sapiens)


name: UDP-alpha-D-glucuronate(out) + UDP-alpha-D-xylose(in) <=> UDP-alpha-D-glucuronate(in) + UDP-alpha-D-xylose(out)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Xenopus tropicalis)


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Xenopus tropicalis)


name: Nephrin mediated activation of N-WASP (Gallus gallus)


name: Caspase-mediated cleavage of GAS2 (Homo sapiens)


name: H2 + n sulfur = H(+) + hydrogen sulfide + (n-1) sulfur


name: H(+)(in) + L-histidine(in) + L-ornithine(out) => H(+)(out) + L-histidine(out) + L-ornithine(in)


name: 2-methyl-1-pyrroline + H(+) + NADPH => (R)-2-methylpyrrolidine + NADP(+)


name: miR-26 binds to the 3'UTR of the ARL4C mRNA (Homo sapiens)


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Mus musculus)


name: fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 (Sus scrofa)


name: (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + A => 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + AH2


name: Corticotropin cleavage from POMC (Bos taurus)


name: Association of Ku heterodimer with ends of DNA double-strand break (Mus musculus)


name: cytidine(60) in tRNA(Asp) + S-adenosyl-L-methionine <=> 5-methylcytidine(60) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 <=> 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + H2O => [CysO sulfur-carrier protein]-C-terminal Gly-Gly + H(+) + L-cysteine


name: 3-hydroxyisopentadecanoyl-CoA + NADP(+) = 3-oxoisopentadecanoyl-CoA + H(+) + NADPH


name: RAC1 binds effectors at the plasma membrane (Drosophila melanogaster)


name: A REH hydrolses atREs to atROL and FAs (Homo sapiens)


name: aminoacetaldehyde + CO2 => 2-aminomalonate semialdehyde + H(+)


name: Cleavage of NODAL proprotein (Homo sapiens)


name: Transfer of NEDD8 to AcM-UBE2F (Dictyostelium discoideum)


name: furan-3-carbaldehyde + hydrogen cyanide = (2S)-2-(furan-3-yl)-2-hydroxyacetonitrile


name: 4-methyl-2-oxopentanoate(out) + H(+)(out) => 4-methyl-2-oxopentanoate(in) + H(+)(in)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + cholesterol => a 1-acyl-sn-glycero-3-phosphocholine + a cholesterol ester


name: JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Xenopus tropicalis)


name: H(+)(in) + spermidine(out) = H(+)(out) + spermidine(in)


name: Release of p-STAT2:p-STAT1 dimer (Sus scrofa)


name: 2 Na(+)(in) + selenocyanate(in) => 2 Na(+)(out) + selenocyanate(out)


name: The Ligand:GPCR:Gz complex dissociates (Xenopus tropicalis)


name: (2E)-docosenoyl-CoA + H(+) + NADPH = docosanoyl-CoA + NADP(+)


name: Class IV antihypertensives bind LTCC multimer (Caenorhabditis elegans)


name: (R)-carnitine + butanoyl-CoA => CoA + O-butanoyl-(R)-carnitine


name: L-dopa + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)


name: Transport of L1 from C-domain to P-domain (Homo sapiens)


name: MRN complex binds RBBP8 (Rattus norvegicus)


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Rattus norvegicus)


name: (+)-sesamin + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) = (+)-sesamin monocatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n)


name: RNA polymerase II complex recruiting activity


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Xenopus tropicalis)


name: KAT5 acetylates ATM at DNA DSBs (Dictyostelium discoideum)


name: (2E)-octenal + H2O + NADP(+) <=> (2E)-octenoate + 2 H(+) + NADPH


name: (8Z,11Z,14Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(8Z,10E,14Z)-eicosatrienoate


name: a ganglioside Ac-O-8-GD2 <=> a ganglioside Ac-O-9-GD2


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Canis familiaris)


name: NAGLU hydrolyses heparan chain(2) (Dictyostelium discoideum)


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Sus scrofa)


name: 2-oxoglutarate + L-prolyl-[Skp1 protein] + O2 => CO2 + succinate + trans-4-hydroxy-L-prolyl-[Skp1 protein]


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Canis familiaris)


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Canis familiaris)


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Drosophila melanogaster)


name: H(+) + H2O + loganin + oxidized [NADPH--hemoprotein reductase] => 7-deoxyloganin + O2 + reduced [NADPH--hemoprotein reductase]


name: Collagen type XIX degradation (Canis familiaris)


name: (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + NADPH => (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + NADP(+)


name: 1,6-dihydroxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-methionine <=> 1-hydroxy-6-methoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-homocysteine


name: GTP + N-acetyl-D-glucosamine <=> GDP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA (Rattus norvegicus)


name: 3-hydroxyglutarate(in) + 3 Na(+)(in) => 3-hydroxyglutarate(out) + 3 Na(+)(out)


name: 5-chloro-L-tryptophan + FAD + 2 H2O => chloride + FADH2 + L-tryptophan + O2


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) (Sus scrofa)


name: Endocytosis of Ca impermeable AMPA receptors (Homo sapiens)


name: tryptophan hydroxylase activator activity


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine = H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine


name: H2O + S-hexadecanoyl-L-cysteinyl-[protein] => H(+) + hexadecanoate + L-cysteinyl-[protein]


name: 1,2,3-trioctanoylglycerol + H2O => dioctanoylglycerol + H(+) + octanoate


name: H(+) + NADPH + O2 + oxytetracycline => 11a-hydroxy-oxytetracycline + H2O + NADP(+)


name: (9Z)-octadecenoyl-CoA + 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate => (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: (2E,6E)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate


name: Disassembly of SR-BI-bound spherical HDL (Sus scrofa)


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Mus musculus)


name: GLI proteins bind SUFU (Canis familiaris)


name: glutamate dehydrogenase [NAD(P)+] activity


name: Formation of Okazaki fragments (Homo sapiens)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Homo sapiens)


name: 26S proteosome degrades ODC holoenzyme complex (Bos taurus)


name: SLCO2B1 has a narrow substrate specificity (Mus musculus)


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Drosophila melanogaster)


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Canis familiaris)


name: 3-hydroxy-4-methylanthranilate + H(+) + S-adenosyl-L-homocysteine => 3-hydroxyanthranilate + S-adenosyl-L-methionine


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Schizosaccharomyces pombe)


name: XPO1 binds p-S69,73 MITF-M (Caenorhabditis elegans)


name: HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH (Homo sapiens)


name: a long-chain fatty acid + ethanolamine => H2O + N-(long-chain fatty acyl)ethanolamine


name: H(+)(in) + L-methionine(out) => H(+)(out) + L-methionine(in)


name: ATP(in) + CoA(in) + H(+)(out) + tetracosanoate(out) <=> AMP(in) + diphosphate(in) + H(+)(in) + tetracosanoyl-CoA(in)


name: ATP + H2O = adenine + D-ribose 5-triphosphate


name: ATP + carbamate = ADP + carbamoyl phosphate


name: CASP8 cleaves N4BP1 at D424, D490 (Homo sapiens)


name: PKC phosphorylates GRK2 (Xenopus tropicalis)


name: beta-D-glucosyl-(1->3)-O-lithocholate + H2O => D-glucose + lithocholate


name: Cleavage of uracil by SMUG1 glycosylase (Xenopus tropicalis)


name: DKC1 binds SHQ1 (Schizosaccharomyces pombe)


name: alpha-D-glucose 1-phosphate + D-gluconate => 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Bos taurus)


name: Recruitment of Telomerase RNP to the Telomeric Chromosome End (Homo sapiens)


name: CO2 + gibberellin A1 + succinate => 2-oxoglutarate + gibberellin A20 + O2


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Homo sapiens)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Danio rerio)


name: T1R1/T1R3 dimer is the umami taste receptor (Homo sapiens)


name: D-erythrose 4-phosphate + L-erythrulose = beta-D-fructose 6-phosphate + glycolaldehyde


name: NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP (Plasmodium falciparum)


name: Dissociation of RAS:RAF complex (Caenorhabditis elegans)


name: Dynamin is recruited to the gap junction plaque (Drosophila melanogaster)


name: PKC autophosphorylates (Rattus norvegicus)


name: Extracellular BTD hydrolyses BCTN (Sus scrofa)


name: (5Z)-tetradecenoyl-CoA + (R)-carnitine <=> CoA + O-(5Z)-tetradecenoyl-(R)-carnitine


name: a ganglioside GT3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GT2 (d18:1(4E)) + H(+) + UDP


name: SEMA4A binds to PLXND1 (Caenorhabditis elegans)


name: SRF:MKL1 binds ITGB1 Gene (Homo sapiens)


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)


name: SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa (Bos taurus)


name: 2-oxobutanoate + L-kynurenine <=> (2S)-2-aminobutanoate + H2O + kynurenate


name: phosphatidylcholine-sterol O-acyltransferase activator activity


name: H2O + O2 + tryptamine <=> H2O2 + indole-3-acetaldehyde + NH4(+)


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Homo sapiens)


name: β1-agonists bind ADRB1 (Rattus norvegicus)


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Sus scrofa)


name: ferruginol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + salviol


name: MICAL1 produces NADP+, H2O2 (Sus scrofa)


name: an N-carbamoyl-D-amino acid + 2 H(+) + H2O => a D-alpha-amino acid + CO2 + NH4(+)


name: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil => 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate


name: a ganglioside Fuc-GD1b + GDP + H(+) => a ganglioside GD1b + GDP-beta-L-fucose


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Rattus norvegicus)


name: UDP-alpha-D-xylose + zeatin = H(+) + O-beta-D-xylosylzeatin + UDP


name: [DsrC protein]-disulfide + H(+) + hydrogen sulfide <=> [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine


name: Factor H binds host cell surface markers (Homo sapiens)


name: AFG3L2 binds mitochondrial inner membrane proteins (Drosophila melanogaster)


name: (+)-thujan-3-one + H(+) + NADPH => (+)-thujan-3-ol + NADP(+)


name: 3-hydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine => 3-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Mus musculus)


name: Phosphorylated STAT5 is released (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine


name: 4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 <=> 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O


name: SUCLG1/G2 cleaves succinyl-CoA (Caenorhabditis elegans)


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Canis familiaris)


name: a 2'-deoxycytidine in single-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in single-stranded DNA + O2


name: an aldopyranose + NAD(+) <=> aldono-1,5-lactone + H(+) + NADH


name: GTSE1 promotes translocation of TP53 to the cytosol (Mus musculus)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: Recruitment of Profilin by Ena/VASP proteins (Mus musculus)


name: Methylation of GMP-cap by RNA Methyltransferase (Sus scrofa)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Homo sapiens)


name: cGMP binds CNG channel to form cGMP:CNG channel (Drosophila melanogaster)


name: 4-(trimethylamino)butanoate + H(+) + NADH + O2 = H2O + NAD(+) + succinate semialdehyde + trimethylamine


name: D-mannose 6-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate


name: acetyl-CoA + AH2 + H(+) + 3 malonyl-CoA + 2 S-adenosyl-L-methionine = A + clavatol + 3 CO2 + 4 CoA + H2O + 2 S-adenosyl-L-homocysteine


name: RHOD translocates to the mitochondrial outer membrane (Xenopus tropicalis)


name: a globoside GalGb4Cer (d18:1(4E)) + H2O <=> an N-acylsphing-4-enine + beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc


name: IDH2 dimer decarboxylates isocitrate (Caenorhabditis elegans)


name: 4-O-beta-D-glucopyranosyl-D-gluconate + H(+) => D-cellobiono-1,5-lactone + H2O


name: (S)-2-amino-6-oxohexanoate => H(+) + H2O + L-1-piperideine-6-carboxylate


name: FGF2:TGFBR3 binding to GIPC1 (Canis familiaris)


name: ABC-type quaternary ammonium compound transporting activity


name: ATM phosphorylates NBN (Drosophila melanogaster)


name: RAC1 and CDC42 activate PAK2 (Gallus gallus)


name: IL17RD binds p-2S MAP2Ks and MAPKs (Rattus norvegicus)


name: 2-demethylmenaquinol-8 + H(+) + trimethylamine N-oxide = 2-demethylmenaquinone-8 + H2O + trimethylamine


name: CSF3 dimer:CSFR binds CSFR (Homo sapiens)


name: (-)-menthol + NADP(+) <=> (1R,4S)-menthone + H(+) + NADPH


name: a 3beta-hydroxysteroid + a triacylglycerol <=> a 1,3-diacylglycerol + a 3beta-hydroxysteroid ester


name: Collagen type II degradation by MMP15 (Homo sapiens)


name: Spherical HDL binds C and E apolipoproteins (Bos taurus)


name: H(+) + NADH + O2 + toluene <=> 4-methylphenol + H2O + NAD(+)


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Saccharomyces cerevisiae)


name: 3,4-dihydroxyphenylacetate + O2 <=> 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)


name: H2O + N-formimidoyl-L-glutamate => formamide + L-glutamate


name: Inactive G alpha (i) reassociates with G beta:gamma (Homo sapiens)


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Xenopus tropicalis)


name: H2O + L-xylono-1,4-lactone => H(+) + L-xylonate


name: NADPH transfers electrons to FDXR (Homo sapiens)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + CO2 + CoA


name: H(+) + L-homocitrulline + phosphate => carbamoyl phosphate + L-lysine


name: acetyl-CoA + streptothricin F <=> CoA + H(+) + N(beta)-acetylstreptothricin F


name: 2 H(+) + metoxuron + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3-(3-chloro-4-methoxylphenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Homo sapiens)


name: HSD17B1 hydrogenates E1 to EST17b (Bos taurus)


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Mus musculus)


name: [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + CO2 + succinate => 2-oxoglutarate + [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + O2


name: Activation of Rac1 by VAV2 (Gallus gallus)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Homo sapiens)


name: 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + neopikromycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Collagen type XV restin release (Rattus norvegicus)


name: a quinol + fumarate => a quinone + succinate


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(28-hydroxyoctacosanoyl)-sphing-4-enine <=> a diacylglycerol + N-(28-(9Z,12Z-octadecadienoyloxy)-octacosanoyl)-sphing-4-enine


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Schizosaccharomyces pombe)


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Mus musculus)


name: ubiquitin ligase complex scaffold activity


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Drosophila melanogaster)


name: BRAF autophosphorylates downstream of RAP1 and NGF (Rattus norvegicus)


name: H(+) + NADH + oxomalonate => hydroxymalonate + NAD(+)


name: eicosanoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (5Z)-eicosenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2-oxopropyl-coenzyme M + CO2 + NADPH => acetoacetate + coenzyme M + NADP(+)


name: (25R)-3beta,4beta-dihydroxycholest-5-en-26-al + H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3beta,4beta-dihydroxycholest-5-en-26-oate + H2O + 2 oxidized [adrenodoxin]


name: (9Z)-octadecenoyl-CoA + 1,2-dihexanoylglycerol = 1,2-dihexanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: C-ter TLR7 dimer binds imiquimod (Gallus gallus)


name: H2O + N-phenylhydroxylamine + 2 NADP(+) => 2 H(+) + 2 NADPH + nitrobenzene


name: 2-dehydro-3-deoxy-L-galactonate + NAD(+) => 3-deoxy-D-glycero-2,5-hexodiulosonate + H(+) + NADH


name: 2-oxoglutarate + L-arginine <=> 5-guanidino-2-oxopentanoate + L-glutamate


name: Activated PPARG binds PTEN gene promoter (Homo sapiens)


name: MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Drosophila melanogaster)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: 1D-myo-inositol 6-phosphate + H2O <=> myo-inositol + phosphate


name: SUMOylation of NPM1 with SUMO2,3 (Sus scrofa)


name: (3S)-citramalyl-CoA => acetyl-CoA + pyruvate


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + diphosphate = 5-amino-4-imidazolecarboxyamide + 5-phospho-alpha-D-ribose 1-diphosphate


name: (9Z,12Z)-octadecadienoate + H2O = (10S)-hydroxy-(12Z)-octadecenoate


name: a ribonucleoside 5'-phosphate + GTP <=> a ribonucleoside 5'-diphosphate + GDP


name: Formation of DSIF complex  (Drosophila melanogaster)