name: a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate => a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate


name: LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) (Homo sapiens)


name: UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG (Mus musculus)


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Saccharomyces cerevisiae)


name: 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region (Homo sapiens)


name: a 1,2-diacyl-3-O-[alpha-D-galactopyranosyl-(1->2)-alpha-D-glucopyranosyl]-sn-glycerol + H(+) + UDP => a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-galactose


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Caenorhabditis elegans)


name: UBA1 adenylates ubiquitin in the cytosol (Plasmodium falciparum)


name: a long-chain fatty acid + CoA + H(+) => a long-chain fatty acyl-CoA + H2O


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O => a 2-acyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: acetaldehyde + CoA + NAD(+) => acetyl-CoA + H(+) + NADH


name: FOXO3 regulates MIR34B,C expression (Homo sapiens)


name: D-cellohexaono-1,5-lactone + H2O <=> D-cellohexaonate + H(+)


name: p-PKR dimer phosphorylates ILF3:ILF2 (Sus scrofa)


name: a glycerophospholipid + H2O = a 2-acyl-sn-glycero-3-phospholipid + a fatty acid + H(+)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Sus scrofa)


name: biotin + H2O + NADP(+) => biotinate sulfoxide + H(+) + NADPH


name: PDPK1 phosphorylates SGK1 (Rattus norvegicus)


name: HMGB1 release from cells (Schizosaccharomyces pombe)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Bos taurus)


name: p-S276-RELA binds RELB (Rattus norvegicus)


name: IL6R binds IL6R inhibitors (Homo sapiens)


name: PIAS1 SUMOylates SP3 with SUMO1 (Sus scrofa)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate


name: 7,8-dihydroxykynurenate + O2 <=> 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+)


name: Cleaved KMT2A dimers translocate to the nucleus (Bos taurus)


name: SAR1 Activation And Membrane Binding (Saccharomyces cerevisiae)


name: (-)-dehydrodiconiferyl acid ketone + a quinol => (-)-dehydrodiconiferyl acid + a quinone


name: 6 Fe(III)-[cytochrome c] + 3 H2O + S-disulfanyl-L-cysteinyl-[SoxY protein] = 6 Fe(II)-[cytochrome c] + 7 H(+) + S-sulfosulfanyl-L-cysteinyl-[SoxY protein]


name: a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP-alpha-D-glucose => a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP


name: ATP + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine => 6-O-phospho-N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine + ADP + H(+)


name: MAT1A multimers transfer Ado from ATP to L-Met (Dictyostelium discoideum)


name: 1,7-dimethylxanthine + S-adenosyl-L-methionine => caffeine + H(+) + S-adenosyl-L-homocysteine


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate


name: O2 + oleanolate + reduced [NADPH--hemoprotein reductase] => cochalate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Homodimerization of VEGF proteins (Danio rerio)


name: a dicarboxylate(out) + sulfate(in) => a dicarboxylate(in) + sulfate(out)


name: cholate + NAD(+) => 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: (9Z)-octadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z)-octadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)


name: 6-chloro-3-hydroxypyridine-2,5-dione + chloride + FAD + 2 H(+) + H2O => 3,6-dichloropyridine-2,5-diol + FADH2 + O2


name: Interaction of IQGAP1 with nephrin (Danio rerio)


name: dehydroepiandrosterone 3-sulfate(out) => dehydroepiandrosterone 3-sulfate(in)


name: PITPNM1,2,3 exchange PI for PA (Bos taurus)


name: Activated FGFR4:p-FRS bind to PPTN11 (Xenopus tropicalis)


name: ROBO1 gene expression is inhibited by LHX2 (Homo sapiens)


name: Ral-GDS binds to Ras-GTP (Drosophila melanogaster)


name: 7,8-dihydroneopterin 3'-phosphate = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde phosphate


name: 2 2-oxoglutarate + gibberellin A53 + H(+) + 3 O2 = 3 CO2 + gibberellin A20 + 2 H2O + 2 succinate


name: SHC1 binds phosphorylated ERBB2 homodimer (Homo sapiens)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Drosophila melanogaster)


name: MARC1,MARC2 reduce N-hydroxylated compounds (Drosophila melanogaster)


name: 5,7-dihydroxy-4-methylphthalide + H2O => 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+)


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Bos taurus)


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Xenopus tropicalis)


name: Active ARF recruits coatomer (Plasmodium falciparum)


name: Syndecans 1, 2 & 4 bind VTN (Rattus norvegicus)


name: (3,5-dihydroxyphenyl)acetyl-CoA + H2O <=> (3,5-dihydroxyphenyl)acetate + CoA + H(+)


name: 30-hydroxy-11-oxo-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = glycyrrhetaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Loading of dopamine into synaptic veiscles (Xenopus tropicalis)


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + AMP + diphosphate => (25S)-3-oxocholest-4-en-26-oate + ATP + CoA


name: STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Canis familiaris)


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Schizosaccharomyces pombe)


name: androst-5-en-3beta,7alpha,17beta-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => androst-5-en-3beta,17beta-diol + O2 + reduced [NADPH--hemoprotein reductase]


name: 3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] <=> 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite


name: (12Z)-10-hydroxyoctadecenoate + H2O => 10,13-dihydroxyoctadecanoate


name: Recruitment and activation of Chk1 (Mus musculus)


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Rattus norvegicus)


name: AGRN binds Integrins alphaVbeta1 (Other beta1-containing integrins) (Homo sapiens)


name: PEX19:class I PMP binds PEX3 (Canis familiaris)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Homo sapiens)


name: ABCE1 binds RNASEL, inhibiting it (Rattus norvegicus)


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Rattus norvegicus)


name: FITM1, FITM2 bind TAGs (Rattus norvegicus)


name: Two DITs combine to form thyroxine (Rattus norvegicus)


name: STARD10 binds LPCAT1 and PC (Xenopus tropicalis)


name: DIT and MIT combine to form triiodothyronine (Canis familiaris)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O <=> a fatty acid + an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate


name: a 1,2-diacyl-sn-glycerol + lipid A 1,4'-bis(2-aminoethyl diphosphate) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A hexaacyl 1-(2-aminoethyl diphosphate)


name: CHDH oxidises Cho to BETALD (Mus musculus)


name: IDO1 dioxygenates L-Trp to NFK (Homo sapiens)


name: DHRS7B reduces GO3P to HXDG3P (Sus scrofa)


name: AMP + diphosphate + OPC-6-CoA => ATP + CoA + OPC-6


name: Haptoglobin binds Hemoglobin (Danio rerio)


name: CERT1-2 complex binds ceramide (Drosophila melanogaster)


name: 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA <=> 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + H(+) + H2O + oxidized [flavodoxin] => a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin]


name: CYP7B1 7-hydroxylates 25OH-CHOL (Sus scrofa)


name: butanoyl-CoA + H2O = butanoate + CoA + H(+)


name: (Z)-alkanethial oxide => (E)-alk-1-en-1-SO-peroxol


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Gallus gallus)


name: (4R)-limonene + A + H2O => (4R)-perillyl alcohol + AH2


name: eNOS translocation from Golgi to Caveolae (Dictyostelium discoideum)


name: H2O + L-selenocystathionine = 2-oxobutanoate + L-selenocysteine + NH4(+)


name: GTP + H(+) + valienol 1-phosphate => diphosphate + GDP-valienol


name: CTP + D-ribose 5-phosphate + H(+) => CDP-D-ribose + diphosphate


name: 3,3',5'-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3,3',5'-triiodo-L-thyronine


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Homo sapiens)


name: AOC3 deaminates BZAM (Rattus norvegicus)


name: Synthesis of dolichyl-phosphate-glucose (Dictyostelium discoideum)


name: ADP + H(+) + O-phospho-L-seryl-[receptor-protein] => ATP + L-seryl-[receptor-protein]


name: H(+) + malonyl-CoA + tetradecanoyl-CoA <=> 3-oxohexadecanoyl-CoA + CO2 + CoA


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Saccharomyces cerevisiae)


name: DENND5A,B exchange GTP for GDP on RAB39 (Gallus gallus)


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Gallus gallus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Xenopus tropicalis)


name: a 12-hydroxy-12-oxojasmonyl-L-alpha-amino acid + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => a 12-hydroxyjasmonyl-L-alpha-amino acid + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: Binding of cAMP to HCN channels (Canis familiaris)


name: [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA => [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl](n) + n CoA


name: gibberellin A4 16alpha,17 epoxidase activity


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Mus musculus)


name: acetate + D-glucosamine => H2O + N-acetyl-D-glucosamine


name: ATP + CoA + dodecanedioate <=> AMP + diphosphate + dodecanedioyl-CoA


name: D-arabinose + NADP(+) => D-arabinono-1,4-lactone + H(+) + NADPH


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Danio rerio)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Mus musculus)


name: L-arabinitol + NAD(+) <=> H(+) + L-arabinose + NADH


name: p-T68-CHEK2 autophosphorylates (Xenopus tropicalis)


name: PIAS4 SUMOylates NR4A2 with SUMO2,3 (Homo sapiens)


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Xenopus tropicalis)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADH


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: pro-defensin alpha 5 is stored in Paneth cell granules (Mus musculus)


name: Stalling of DNA replication fork and RPA binding (Plasmodium falciparum)


name: deoxyribonuclease (pyrimidine dimer) activity


name: RAC1 and CDC42 activate PAK2 (Caenorhabditis elegans)


name: CoA + H(+) + N-acetyltryptamine => acetyl-CoA + tryptamine


name: (20S)-ginsenoside F2 + UDP-alpha-D-glucose => (20S)-ginsenoside Rd + H(+) + UDP


name: Activation of Protein Kinase C novel isoforms (Canis familiaris)


name: PIP3 recruits PDPK1 to the membrane (Plasmodium falciparum)


name: a 21-hydroxy-C21-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase]


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Rattus norvegicus)


name: (3R)-hydroxy-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA => (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H2O


name: (E,E)-piperoyl-AMP + CoA => (E,E)-piperoyl-CoA + AMP + H(+)


name: cGMP is degraded by PDEs (Caenorhabditis elegans)


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Sus scrofa)


name: ARL2:GTP bind PDE6D on KRAS4B (Rattus norvegicus)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Gallus gallus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Canis familiaris)


name: Formation of PRC2-EZH2 complex (Homo sapiens)


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Danio rerio)


name: mTORC1 phosphorylates MAF1 (Homo sapiens)


name: 4beta-hydroxymethyl-4alpha-methylzymosterol + H(+) + NADH + O2 = 4beta-formylmethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H2O + NAD(+)


name: Initial activation of proMMP2 by MMP1, 7 (Drosophila melanogaster)


name: H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Replication transcription complex binds SARS-CoV-1 genomic RNA (Homo sapiens)


name: Dopamine is oxidised to noradrenaline (Drosophila melanogaster)


name: p-S158,221-HuR binds mRNA (Drosophila melanogaster)


name: carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)


name: Translocation of PMAIP1 (NOXA) to mitochondria (Sus scrofa)


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Gallus gallus)


name: (S)-cystathionine ketimine + 2 H(+) + NADH => (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NAD(+)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)


name: 1-hexadecanoylglycerone 3-phosphate + octadecan-1-ol = 1-O-octadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1,2-dihexanoylglycerol => 1,2-dihexanoyl-3-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + CoA


name: chloride + FADH2 + O2 + tetracycline => 7-chlorotetracycline + FAD + H(+) + 2 H2O


name: 3'-phosphoadenylyl sulfate + glycolithocholate = adenosine 3',5'-bisphosphate + H(+) + sulfoglycolithocholate


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Mus musculus)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Xenopus tropicalis)


name: NT5C2 tetramer dephosphorylates RBV-MP (Sus scrofa)


name: Mitochondrial uptake of beta-alanine (Homo sapiens)


name: A + Delta(1)-dihydrotestosterone + H2O <=> 17beta-hydroxyandrostan-1,3-dione + AH2


name: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP


name: D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] <=> D-fructose 1-phosphate(in) + L-histidyl-[protein]


name: S-adenosyl-L-methionine + syringetin = 3,3',5'-O-trimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Gallus gallus)


name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA (Drosophila melanogaster)


name: a globoside Gb3Cer + UDP-alpha-D-galactose => a globoside GalGb3Cer + H(+) + UDP


name: FAD + H(+) + pentadecanoyl-CoA <=> (2E)-pentadecenoyl-CoA + FADH2


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Homo sapiens)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Dictyostelium discoideum)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Mus musculus)


name: POLK incorporates dNMP opposite to damaged DNA base (Xenopus tropicalis)


name: ATP + L-threonyl-[tau protein] => ADP + H(+) + O-phospho-L-threonyl-[tau protein]


name: acetyl-CoA + H2O => acetate + CoASH (Caenorhabditis elegans)


name: H(+) + malonyl-[ACP] + octanoyl-[ACP] = 3-oxodecanoyl-[ACP] + CO2 + holo-[ACP]


name: IL26:IL20RA:JAK1 binds IL10RB:TYK2 (Gallus gallus)


name: ADP + H(+) + N-hexanoylsphing-4-enine 1-phosphate => ATP + N-(hexanoyl)sphing-4-enine


name: 3-hydroxypropanoyl-CoA + AMP + diphosphate => 3-hydroxypropanoate + ATP + CoA


name: (R)-glycerate + ATP <=> (2R)-2-phosphoglycerate + ADP + H(+)


name: ATM dimer:PEX5 phosphorylates PEX5 (Sus scrofa)


name: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP <=> 8-desmethylnovobiocic acid + AMP + diphosphate


name: (R)-lactate(in) + citrate(out) <=> (R)-lactate(out) + citrate(in)


name: (3E)-3,4-didehydrorhodopin + AH2 => A + rhodopin


name: 3-oxochola-4,17-dien-22-oyl-CoA + AH2 => 3-oxochol-4-en-22-oyl-CoA + A


name: ABCB4 transports PC from plasma membrane to extracellular region (Homo sapiens)


name: 5alpha-androstane-3alpha,17beta-diol + NADP(+) => androsterone + H(+) + NADPH


name: GTP-dependent polynucleotide 5'-hydroxyl-kinase activity


name: ATR phosphorylates RPA2 (Caenorhabditis elegans)


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Caenorhabditis elegans)


name: (17Z)-hexacosenoyl-CoA + sphinganine => CoA + H(+) + N-[(17Z)-hexacosenoyl]dihydrosphingosine


name: (3R)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) <=> 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + NADH


name: a fatty acid + a lysoGb3(d18:1(4E)) => a globoside Gb3Cer (d18:1(4E)) + H2O


name: Opioid receptors bind opioid peptides (Xenopus tropicalis)


name: SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Rattus norvegicus)


name: 2'-deoxycytidine(in) + H(+)(in) <=> 2'-deoxycytidine(out) + H(+)(out)


name: [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine => [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate


name: Aquaporin-1 passively transports water out of cell (Sus scrofa)


name: Caspase-8 activates BID by cleavage (Canis familiaris)


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Canis familiaris)


name: 5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine => 2-iminoacetate + 5'-deoxyadenosine + 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + H(+) + L-methionine


name: B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Caenorhabditis elegans)


name: CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) (Mus musculus)


name: TFIIH binds GG-NER site to form a verification complex (Canis familiaris)


name: Activated FGFR1 phosphorylates SHC1 (Mus musculus)


name: dGTP + H2O <=> 2'-deoxyguanosine + H(+) + triphosphate


name: all-trans-4,4'-diaponeurosporene + FAD + H(+) <=> all-trans-4,4'-diapolycopene + FADH2


name: cholesterol + hexadecanoyl-CoA = cholesteryl hexadecanoate + CoA


name: PHF8 demethylates histone H4K20me1 (Schizosaccharomyces pombe)


name: 16 ATP + 16 H2O + N2 + 8 reduced [2Fe-2S]-[ferredoxin] = 16 ADP + 6 H(+) + H2 + 2 NH4(+) + 8 oxidized [2Fe-2S]-[ferredoxin] + 16 phosphate


name: 7,8-dihydroneopterin 3'-triphosphate => 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde triphosphate


name: IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Homo sapiens)


name: a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Mus musculus)


name: Extracellular BTD hydrolyses BCTN (Canis familiaris)


name: Caspase-6 translocates to the nucleus (Gallus gallus)


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Homo sapiens)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Canis familiaris)


name: ALPK1 binds ADP-heptose (Canis familiaris)


name: SERPINB13 binds cathepsin L (Caenorhabditis elegans)


name: H2O + N-acetyl-D-muramate 6-phosphate => N-acetyl-D-muramate + phosphate


name: 2-oxoglutarate(in) + taurocholate(out) <=> 2-oxoglutarate(out) + taurocholate(in)


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Rattus norvegicus)


name: ATP + hexadecanoate + holo-[ACP] = AMP + diphosphate + hexadecanoyl-[ACP]


name: 1-O-hexadecyl (9Z)-hexadecenoate + CoA => (9Z)-hexadecenoyl-CoA + hexadecan-1-ol


name: Formation of the cap-binding eIF4F complex (Schizosaccharomyces pombe)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Mus musculus)


name: Autoglucosylation of GYG2 complexed with GYS2-a (Saccharomyces cerevisiae)


name: ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA (Sus scrofa)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+) => an alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Mus musculus)


name: 4-phenylbutan-2-amine + H2O + NAD(+) = 4-phenylbutan-2-one + H(+) + NADH + NH4(+)


name: 17beta-estradiol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: Fe(II)2-[transferrin] + H(+) + NAD(+) = Fe(III)2-[transferrin] + NADH


name: TAF1 phosphorylates TP53 (Xenopus tropicalis)


name: PTPN4 gene expression is stimulated by MECP2 (Homo sapiens)


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Homo sapiens)


name: RP2 activates the GTPase activity of ARL3 (Mus musculus)


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Danio rerio)


name: cyclin-dependent protein kinase activity


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + ATP = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+)


name: anthocyanin A8 + CoA => anthocyanin A6 + malonyl-CoA


name: a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GM2 (d18:1(4E)) + H(+) + UDP


name: XYLB phosphorylates D-xylulose (Caenorhabditis elegans)


name: H2O + L-threonyl-L-serine => L-serine + L-threonine


name: STAT1 and STAT3 dimers translocate to the nucleus (Sus scrofa)


name: cyclic tetraadenylate = 2 5'-hydroxy-diadenylate 2',3'-cylic phosphate


name: GRB2:SOS1 complex binds to the active receptor (Gallus gallus)


name: NTP Binds Active Site of RNA Polymerase II (Mus musculus)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Sus scrofa)


name: Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding (Homo sapiens)


name: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose => CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + H(+)


name: OSCN- reacts with Cys residues (Homo sapiens)


name: factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) (Homo sapiens)


name: 2 H(+) + L-aspartate + NADH => H2O + L-aspartate 4-semialdehyde + NAD(+)


name: ATP + holo-[peptidyl-carrier protein] + L-cysteine <=> AMP + diphosphate + L-cysteinyl-[peptidyl-carrier protein]


name: Oligomerization of BCL10 and MALT1 (Rattus norvegicus)


name: protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Drosophila melanogaster)


name: 7-dehydrocholesterol + A + H2O = AH2 + cholesta-5,7-dien-3beta,25-diol


name: 2-oxoglutarate + L-ectoine + O2 => 5-hydroxyectoine + CO2 + succinate


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Dictyostelium discoideum)


name: anthranilate + malonyl-CoA = CoA + N-malonylanthranilate


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA = (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H2O


name: 4-hydroxy-L-proline(in) + H(+)(in) <=> 4-hydroxy-L-proline(out) + H(+)(out)


name: SUMOylation of MKL1 with SUMO1 (Sus scrofa)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Saccharomyces cerevisiae)


name: 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one = (E)-caffeoylpyruvate + CO2 + hnu


name: ATXN3 family cleave Ub chains (Drosophila melanogaster)


name: CO2 + pentalenolactone F + succinate => 2-oxoglutarate + O2 + pentalenolactone E


name: berkeleytrione + 2 CO2 + H2O + 2 succinate => 2 2-oxoglutarate + 2 O2 + preaustinoid A


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Bos taurus)


name: Elongation Of The Telomeric Chromosome End (Mus musculus)


name: pppA(2'-5')pG => 3',2'-cGAMP + diphosphate


name: HHAT palmitoylates Hh N-terminal fragment (Rattus norvegicus)


name: (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP => indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose


name: ERBB2 KD mutants bind trastuzumab (Homo sapiens)


name: ATP + D-alanine + D-serine = ADP + D-alanyl-D-serine + H(+) + phosphate


name: 3-dimethylallyl-4-hydroxymandelate + O2 => 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O


name: BGN binds Collagen types I, VI, (IX) (Canis familiaris)


name: Spherical HDL binds membrane-associated free cholesterol and phospholipids (Rattus norvegicus)


name: H(+)(out) + sucrose(out) => H(+)(in) + sucrose(in)


name: Homodimerization of ERBB4 (Gallus gallus)


name: (24S)-hydroxycholesterol 24-sulfate + adenosine 3',5'-bisphosphate + H(+) => (24S)-hydroxycholesterol + 3'-phosphoadenylyl sulfate


name: (R)-carnitine(out) + O-octanoyl-(R)-carnitine(in) <=> (R)-carnitine(in) + O-octanoyl-(R)-carnitine(out)


name: 4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA + H(+)


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: p-ERK phosphorylates WAVEs and ABI (Sus scrofa)


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Homo sapiens)


name: Transcriptional activation of FASN monomer gene by ChREBP:MLX (Homo sapiens)


name: 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 <=> 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: STING binds cyclic GMP-AMP (Gallus gallus)


name: EHMT1:EHMT2 methylates IL6 promoter (Bos taurus)


name: DFF dissociates from importin-alpha:importin-beta (Bos taurus)


name: 2-(acylamino)ethyl fatty acid + a 2-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylethanolamine


name: type IV site-specific deoxyribonuclease activity


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Canis familiaris)


name: NTPDase8 hydrolyzes nucleoside triphosphates (Sus scrofa)


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine => 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester


name: G beta-gamma complex and PIP3 recruit BTK to membrane (Canis familiaris)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Sus scrofa)


name: ATP(in) + CoA(in) + H(+)(out) + tetracosanoate(out) = AMP(in) + diphosphate(in) + H(+)(in) + tetracosanoyl-CoA(in)


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Rattus norvegicus)


name: D-galactose(in) + H(+)(in) <=> D-galactose(out) + H(+)(out)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + NAD(+) => androst-4-ene-3,11,17-trione + H(+) + NADH


name: Raf dimer inhibitors bind RAF heterodimers (Sus scrofa)


name: Association of cell cycle proteins with the APC/C:Cdh1 complex (Canis familiaris)


name: Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) (Homo sapiens)


name: adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)


name: FLNA binds PAK1 (Drosophila melanogaster)


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-pyrethrolone => CoA + pyrethrin II


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Mus musculus)


name: LONP1 degrades mitochondrial inner membrane proteins (Schizosaccharomyces pombe)


name: Telomere shortening during replicative exhaustion (Sus scrofa)


name: a cis-3-alkyl-4-alkyloxetan-2-one = a cis-alkene + CO2


name: 4-chlorophenylacetonitrile + 2 H2O <=> 4-chlorophenylacetate + NH4(+)


name: Expression of Carbonic Anhydrase IX (CA9) (Homo sapiens)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Rattus norvegicus)


name: UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Rattus norvegicus)


name: MET dimers autophosphorylate (Mus musculus)


name: Uncoupled eNOS favours the formation of superoxide (Saccharomyces cerevisiae)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + H(+) + hexadecanoate


name: Internal Methylation of mRNA (Canis familiaris)


name: (E)-4-coumaroyl-CoA + (E)-feruloylacetyl-CoA + H2O => CO2 + 2 CoA + demethoxycurcumin


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Gallus gallus)


name: p-4Y-SIRPA:CD47 binds PTK2B (Canis familiaris)


name: Recruitment of HDAC1 by p107 (RBL1) (Canis familiaris)


name: Potassium voltage-gated channels close in reponse to PKA (Plasmodium falciparum)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Bos taurus)


name: RGGT binds the RAB-binding subunit (Rattus norvegicus)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Homo sapiens)


name: N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine => (9Z,12Z,15Z)-octadecatrienamide + glyoxylate


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate <=> 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + 2-oxoglutarate + H(+) + H2O


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate <=> 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: ZNF423 recruits NuRD to EBF2 target genes (Homo sapiens)


name: (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin] => (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin]


name: Nucleotide exchange on RAB1 (Dictyostelium discoideum)


name: CoA + ethyl hexanoate => ethanol + hexanoyl-CoA


name: Inactivation of MAP2K1 by CDK1 (Bos taurus)


name: ADP + H(+) + sphing-4-enine 1-phosphate => ATP + sphing-4-enine


name: a nucleoside 3',5'-cyclic phosphate + H2O => a nucleoside 5'-phosphate + H(+)


name: H2O + O-phospho-L-threonyl-[protein] <=> L-threonyl-[protein] + phosphate


name: PLL kinase binds to TL:WEK:MYD88:TUB 'signalling complex' (Drosophila melanogaster)


name: BRAP binds KSR1:MARK3 (Dictyostelium discoideum)


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Schizosaccharomyces pombe)


name: H2O + O2 + putrescine <=> 4-aminobutanal + H2O2 + NH4(+)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Xenopus tropicalis)


name: Na(+)(out) + O-acyl-(R)-carnitine(out) => Na(+)(in) + O-acyl-(R)-carnitine(in)


name: a ganglioside GA2 + H2O <=> a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-acetyl-beta-D-galactosamine


name: 2 AMP + didemethylasterriquinone D + 2 diphosphate + H(+) => 2 ATP + 2 indole-3-pyruvate


name: D-mannitol 1-phosphate + NAD(+) <=> beta-D-fructose 6-phosphate + H(+) + NADH


name: ALDH8A1 oxidises 9cRAL to 9cRA (Caenorhabditis elegans)


name: WWOX binds ERBB4s80 (Drosophila melanogaster)


name: Kinesin-1 is a heterotetramer (Canis familiaris)


name: cytidine(2499) in 23S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(2499) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: MeSeOH is reduced to MeSeH by TXNRD1 (Mus musculus)


name: O-atom dealkylation of dextromethorphan (Danio rerio)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Rattus norvegicus)


name: EGF-TM7 receptors bind chondroitin sulphate (Rattus norvegicus)


name: ROS oxidize thioredoxin (Dictyostelium discoideum)


name: ATP + H(+) + nonanoate <=> diphosphate + nonanoyl-AMP


name: 2-oxoglutarate + CoA + NAD(+) <=> CO2 + NADH + succinyl-CoA


name: MAOB:FAD oxidatively deaminates of PEA (Mus musculus)


name: a 5'-end diphospho-adenosine in mRNA + H(+) + phosphate => a 5'-end triphospho-adenosine in mRNA + H2O


name: H2O + sinigrin <=> (Z)-N-(sulfonatooxy)prop-2-enimidothioate + D-glucose + H(+)


name: acetophenone + 2 ATP + H2O + hydrogencarbonate <=> 3-oxo-3-phenylpropanoate + 2 ADP + 2 H(+) + 2 phosphate


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: glucuronoxylan D-glucuronate + n S-adenosyl-L-methionine <=> glucuronoxylan 4-O-methyl-D-glucuronate + n H(+) + n S-adenosyl-L-homocysteine


name: 1-O-alkyl-2,3-diacylglycerol + CoA => 1-O-alkyl-3-acylglycerol + an acyl-CoA


name: Association of procollagen type XXVII (Xenopus tropicalis)


name: GBF1 recruits ARF:GDP to the Golgi (Rattus norvegicus)


name: nocardicin E + S-adenosyl-L-methionine = H(+) + isonocardicin A + S-methyl-5'-thioadenosine


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-corvol ether B + diphosphate


name: Exocytosis of secretory granule membrane proteins (Sus scrofa)


name: (9Z)-octadecenoate + O2 <=> (8E,10S)-10-hydroperoxy-octadeca-8-enoate


name: p38MAPK phosphorylates MSK1 (Bos taurus)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Mus musculus)


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Mus musculus)


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+)


name: 3'-UMP + H(+) => 2',3'-cyclophospho-UMP + H2O


name: CHST14 transfers SO4(2-) to GalNAc in dermatan or DS (Homo sapiens)


name: H2O2 oxidises ferrohemoglobin to MetHb (Canis familiaris)


name: "Peptidylamino-acid hydrolases or acylamino-acid hydrolases"


name: (2S)-naringenin + dimethylallyl diphosphate = diphosphate + sophoraflavanone B


name: ATP4A:ATP4B exchanges K+ for H+ (Homo sapiens)


name: 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)


name: cytidine(out) + Na(+)(out) = cytidine(in) + Na(+)(in)


name: Phosphorylation of MEF2 proteins by p38 (Mus musculus)


name: Constitutive phosphorylation  by pERK1/2 (Drosophila melanogaster)


name: 2 Fe(III)-[cytochrome cL] + methanol <=> 2 Fe(II)-[cytochrome cL] + formaldehyde + 2 H(+)


name: SHC1 binds P-ERBB4 isoform dimers (Mus musculus)


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Xenopus tropicalis)


name: deoxynucleoside triphosphate hydrolase activity


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside + H(+) + triphosphate


name: kainate receptor binds glutamate (Sus scrofa)


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Rattus norvegicus)


name: 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: PRC1 SUMOylates CTBP1 with SUMO1 (Gallus gallus)


name: ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) (Gallus gallus)


name: NFE2L2 binds the PGD gene (Homo sapiens)


name: 3-hydroxyicosanoyl-CoA + NADP(+) <=> 3-oxoeicosanoyl-CoA + H(+) + NADPH


name: PHF20 binds TP53 dimethylated on K370 and K382 (Sus scrofa)


name: [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + H(+) + UDP => [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose


name: succinylCoA + GDP + Pi <=> succinate + CoASH + GTP (Gallus gallus)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Danio rerio)


name: L-glutamate + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose => 2-oxoglutarate + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine


name: Association of procollagen type VIII (Homo sapiens)


name: Activation of RAC1 by VAV2/3 (Mus musculus)


name: mRNA7 is translated to protein 7a (Homo sapiens)


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Mus musculus)


name: protein-phosphocysteine-mannitol phosphotransferase system transporter activity


name: Multiubiquitination of APC/C-associated Cdh1 (Rattus norvegicus)


name: H2O + plasmodiophorol B = plasmodiophorol C


name: Src kinases phosphorylate VAV (Rattus norvegicus)


name: (S)-acetoin + H(+) + NADH => (S,S)-butane-2,3-diol + NAD(+)


name: guanosine(26) in tRNA + 2 S-adenosyl-L-methionine <=> 2 H(+) + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine


name: Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester


name: ACBD4,5 bind MCFA-CoA and LCFA-CoA (Sus scrofa)


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Canis familiaris)


name: 6-decylubiquinone + 2 thiosulfate => 6-decylubiquinol + tetrathionate


name: Translocation and activation of PKC alpha in response to WNT signaling (Homo sapiens)


name: Conformational change in gp120 of Env oligomer (Homo sapiens)


name: all-trans-4,4'-diapophytofluene + FAD + H(+) = all-trans-4,4'-diapo-zeta-carotene + FADH2


name: CUL3:RBX1 ubiquitinates KEAP1 (Canis familiaris)


name: Formation of DSIF:NELF:early elongation complex (Mus musculus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Rattus norvegicus)


name: Interaction of PAK1 with Rac1-GTP (Mus musculus)


name: DEK binds TFAP2A homodimers (Mus musculus)


name: 3beta-hydroxy-5beta-pregnane-20-one + H(+) + NADPH <=> 3beta,20alpha-dihydroxy-5beta-pregnane + NADP(+)


name: DCC interacts with DIP13alpha (Sus scrofa)


name: H2O + L-cysteine + O2 => 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)


name: AH2 + O2 + pregna-4,9(11)-diene-3,20-dione <=> 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O


name: glucuronate transmembrane transporter activity


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Xenopus tropicalis)


name: (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+)


name: CYP2U1 19-hydroxylates ARA (Xenopus tropicalis)


name: guanine + NAD(+) => H(+) + N(2)-(ADP-D-ribosyl)-guanine + nicotinamide


name: trans-zeatin + UDP-alpha-D-glucose = H(+) + O-beta-D-glucosyl-trans-zeatin + UDP


name: NUBPL transfers 4Fe-4S to Complex I subunits (Drosophila melanogaster)


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Canis familiaris)


name: guanosine 3'-diphosphate 5'-triphosphate + H2O <=> guanosine 3',5'-bis(diphosphate) + H(+) + phosphate


name: Active G alpha (z) binds RGS proteins (Xenopus tropicalis)


name: ALDHs oxidise atRAL to atRA (Canis familiaris)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = erythrodiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Collagen type XIII ectodomain shedding (Canis familiaris)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Drosophila melanogaster)


name: Phosphorylation of Cdh1 by Cyclin B1:Cdc2 (Mus musculus)


name: 1D-myo-inositol 2,3-bisphosphate + H2O => 1D-myo-inositol 2-phosphate + phosphate


name: a sphingomyelin + H2O <=> a carboxylate + sphing-4-enine-phosphocholine


name: 2-methylbutan-1-ol + hexanoyl-CoA => 2-methylbutyl hexanoate + CoA


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Bos taurus)


name: AcK-NFE2L2 binds the ABCF2 gene (Homo sapiens)


name: RANBP2 SUMOylates PML with SUMO2 (Sus scrofa)


name: 2-hydroxybenzoyl-5'-AMP + holo-[ACP] => AMP + H(+) + salicyl-[ACP]


name: PTP1B dephosphorylates JAK2 (Homo sapiens)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)


name: (3Z)-phycoerythrobilin + oxidized 2[4Fe-4S]-[ferredoxin] = 15,16-dihydrobiliverdin + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Caenorhabditis elegans)


name: Interaction of integrin alphaDbeta2 with fibrin (Rattus norvegicus)


name: Cis-homodimerization of nectins (Gallus gallus)


name: 2,2-dimethylpropanal + hydrogen cyanide => (2S)-2-hydroxy-3,3-dimethylbutanenitrile


name: cyclic nucleotide-activated monoatomic ion channel activity


name: 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + neopikromycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO2 + 4 CoA + trans-resveratrol


name: 4-hydroxyphenylacetaldehyde oxime monooxygenase activity


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Dictyostelium discoideum)


name: TRAF6 polyubiquitinates NRIF (Homo sapiens)


name: H2O + trans-2,3-epoxysuccinate => (2R,3S)-tartrate


name: 3'-phosphoadenylyl sulfate + a phenolic steroid => a phenolic steroid 3-O-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: (9Z,12Z,15Z)-hexadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: an inositol-1-phosphoceramide + GDP-alpha-D-mannose = an alpha-mannosylinositol-1-phosphoceramide + GDP + H(+)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: TP53 stimulates RABGGTA expression (Homo sapiens)


name: (20S)-ginsenoside Rg3 + D-glucose => (20S)-ginsenoside Rd + H2O


name: TP53 and E2F4 bind the CDC25C gene (Homo sapiens)


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + ATP + CoA <=> 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-CoA + AMP + diphosphate


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP


name: AGO1,2:small RNA complexes interact with chromatin (Homo sapiens)


name: all-trans-4-hydroxy-13,14-dihydroretinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-4-oxo-13,14-dihydroretinoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of COPII vesicle (Homo sapiens)


name: (R)-malate + a quinone = a quinol + enol-oxaloacetate


name: cytochrome-b5 reductase activity, acting on NAD(P)H


name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 (Homo sapiens)


name: acrolein + H2O + NAD(+) => acrylate + 2 H(+) + NADH


name: 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA => benzoyl-CoA + 2 H(+) + 3 malonyl-CoA


name: (2R,3S)-piscidate + (E)-caffeoyl-CoA => cimicifugate D + CoA


name: Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: FUT3 transfers Fuc to Type 1 MSGG to form sLeA (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-choline <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: Elastin degradation by elastin-degrading extracellular proteinases (Homo sapiens)


name: SMAC (DIABLO) binds XIAP (Rattus norvegicus)


name: SLC22A1 transports Cipro into renal cell (Gallus gallus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Homo sapiens)


name: NNT dimer transfers proton from NADPH to NAD+ (Plasmodium falciparum)


name: Keratin type I binds keratin type II (Danio rerio)


name: 2-(2-methylsulfanyl)ethylmaleate + H2O => 3-(2-methylsulfanyl)ethylmalate


name: ADP + D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + H(+) => ATP + D-glycero-alpha-D-manno-heptose 7-phosphate


name: N-acetyl-D-muramate + phosphate => H2O + N-acetyl-D-muramate 6-phosphate


name: butanoyl-CoA + O2 = (2E)-butenoyl-CoA + H2O2


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Mus musculus)


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Rattus norvegicus)


name: ADP + C-terminal S-cyanate-L-cysteinyl-[HypE protein] + H(+) + phosphate => ATP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein]


name: MET bound PI3K generates PIP3 (Gallus gallus)


name: Expression of Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) (Homo sapiens)


name: ATP + H(+) + NADPH + pentanoate => AMP + diphosphate + NADP(+) + pentanal


name: CUL3:RBX1 ubiquitinates KEAP1 (Sus scrofa)


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Dictyostelium discoideum)


name: L-glutamine(in) + L-threonine(out) + Na(+)(out) => L-glutamine(out) + L-threonine(in) + Na(+)(in)


name: ATP + glutathione(in) + H2O + taurochenodeoxycholate(in) <=> ADP + glutathione(out) + H(+) + phosphate + taurochenodeoxycholate(out)


name: an aromatic primary alcohol + NAD(+) = an aromatic aldehyde + H(+) + NADH


name: 2-oxoglutarate + dodecanoyl-CoA + O2 => 2-hydroxydodecanoyl-CoA + CO2 + succinate


name: Squalene is oxidized to its epoxide (Dictyostelium discoideum)


name: H2O + hexadecanoyl-CoA = adenosine 3',5'-bisphosphate + 2 H(+) + S-hexadecanoyl-4'-phosphopantetheine


name: CYP4F12 18-hydroxylates ARA (Sus scrofa)


name: a 2-acylglycerol + H2O = a carboxylate + glycerol + H(+)


name: pseudouridine(54/55) in tRNA => uridine(54/55) in tRNA


name: ARL3:GTP binds the UNC119B complex (Danio rerio)


name: (2E,6E)-farnesyl diphosphate = diphosphate + pentalenene


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Sus scrofa)


name: 15-cis-phytoene + 4 A => 4 AH2 + all-trans-lycopene


name: apigenin 7-O-beta-D-glucoside + H2O => apigenin + beta-D-glucose


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)


name: a D-hexose + an acyl phosphate => a carboxylate + D-hexose phosphate + H(+)


name: MANBA hydrolyses GlcNAc:Man (Xenopus tropicalis)


name: Autocatalytic phosphorylation of FGFR4 (Caenorhabditis elegans)


name: paromamine + UDP-alpha-D-kanosamine <=> H(+) + kanamycin C + UDP


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Homo sapiens)


name: Phosphorylation of STAT2 (Xenopus tropicalis)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: 5alpha-androstane-3beta,17beta-diol + NADP(+) => 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH


name: O2 + prostaglandin H2 + reduced [NADPH--hemoprotein reductase] <=> 19-hydroxyprostaglandin H2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetate(in) + H(+)(in) => acetate(out) + H(+)(out)


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Mus musculus)


name: (3R)-hydroxyoctadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O


name: Abortive Initiation After Second Transition (Mus musculus)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Sus scrofa)


name: ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] => dihydroserpentine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Dictyostelium discoideum)


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Rattus norvegicus)


name: H2O + N,1-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(9Z-octadecenoyl) ethanolamine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine => 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: Activation of Rho by LARG and PDZ-RhoGEF (Rattus norvegicus)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Canis familiaris)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate


name: a dolichyl phosphate + an oligosaccharide-(1->4)-N-acetyl-beta-D-glucosamine-(1->4)-N-acetyl-alpha-D-glucosamine 1-phosphate + 2 H(+) => a dolichyl diphosphooligosaccharide + H2O


name: MAP3K5 phosphorylates MKK3 and MKK6 (Canis familiaris)


name: Association of mTERF with the termination sequence (Mus musculus)


name: TGFBR3_mem cleavage by MMPs (Rattus norvegicus)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Mus musculus)


name: AKT1 phosphorylates NOTCH4 (Mus musculus)


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Homo sapiens)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Mus musculus)


name: RHOT1 hydrolyzes GTP (Caenorhabditis elegans)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Schizosaccharomyces pombe)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Gallus gallus)


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Mus musculus)


name: SALL4 binds the PTEN gene promoter (Homo sapiens)


name: (9R)-hydroperoxy-(10E,12Z)-octadecadienoate => (9Z,12Z)-octadecadienoate + O2


name: allokutznerene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: Initial activation of proMMP13 by MMP3 (Caenorhabditis elegans)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Rattus norvegicus)


name: S-Farn-Me KRAS4B binds calmodulin (Gallus gallus)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Bos taurus)


name: ATP + holo-[peptidyl-carrier protein] + L-arginine <=> AMP + diphosphate + L-arginyl-[peptidyl-carrier protein]


name: 3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite


name: "assimilatory sulfite reductase (ferredoxin)"


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Bos taurus)


name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Drosophila melanogaster)


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Sus scrofa)


name: NFkB complex translocates from the cytosol to the nucleus (Rattus norvegicus)


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Saccharomyces cerevisiae)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Gallus gallus)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Saccharomyces cerevisiae)


name: dehydroepiandrosterone 3-sulfate(out) + n H(+)(out) = dehydroepiandrosterone 3-sulfate(in) + n H(+)(in)


name: 6-carboxy-5,6,7,8-tetrahydropterin + H(+) => 7-carboxy-7-deazaguanine + NH4(+)


name: Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)


name: (+-)-pavine + S-adenosyl-L-methionine => H(+) + N-methylpavine + S-adenosyl-L-homocysteine


name: FGFRL1 binds SPRED1/2 (Xenopus tropicalis)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Dictyostelium discoideum)


name: FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS (Homo sapiens)


name: NADPH + 2 oxidized [cytochrome P450] = H(+) + NADP(+) + 2 reduced [cytochrome P450]


name: 2'-deoxycytidine + ATP = ADP + dCMP + H(+)


name: Elongating transcript encounters a lesion in the template (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 14-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: UCHL3, SENP8 cleave NEDD8 (Rattus norvegicus)


name: 7alpha,8alpha-epoxy-5alpha-cholestan-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => lathosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Mus musculus)


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Xenopus tropicalis)


name: [(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O = [(1->4)-3,6-bisphospho-alpha-D-glucosyl](n) + n AMP + 2n H(+) + n phosphate


name: AMP + diphosphate + H(+) + staphyloferrin B => 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP


name: Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Homo sapiens)


name: GTSE1 promotes translocation of TP53 to the cytosol (Canis familiaris)


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-hexanoyl ethanolamine => H2O + N-hexanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine


name: Activated FGFR2 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: Degradation of ubiquitinated SMAD3 (Drosophila melanogaster)


name: PIN1 mediated IRF3 degradation (Homo sapiens)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Xenopus tropicalis)


name: H(+) + NADPH + O2 + tetracycline = 11a-hydroxytetracycline + H2O + NADP(+)


name: glutaryl-CoA + 2 H(+) + oxidized [electron-transfer flavoprotein] = (2E)-butenoyl-CoA + CO2 + reduced [electron-transfer flavoprotein]


name: Interaction of Tie2 and Shc1 (Canis familiaris)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Homo sapiens)


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Drosophila melanogaster)


name: 2-amino-5-chloromuconate 6-semialdehyde => 2-amino-5-chlorophenol + O2


name: 3-hydroxycyclohexanone + A <=> AH2 + cyclohexane-1,3-dione


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: an acyl-CoA(out) + ATP + H2O = ADP + an acyl-CoA(in) + H(+) + phosphate


name: Pro-beta-NGF and mature beta-NGF are secreted (Rattus norvegicus)


name: A + gibberellin A12 aldehyde + H2O <=> AH2 + gibberellin A12 + H(+)


name: Association of  PARVA with TESK1 (Gallus gallus)


name: ATP + H2O + L-cysteine(out) <=> ADP + H(+) + L-cysteine(in) + phosphate


name: 4'''-demalonylsalvianin + malonyl-CoA => CoA + salvianin


name: G-beta:G-gamma inhibits Adenylate cyclase (Canis familiaris)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Mus musculus)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Sus scrofa)


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Dictyostelium discoideum)


name: 3-oxoheptanoyl-[ACP] + CO2 + CoA => H(+) + malonyl-[ACP] + pentanoyl-CoA


name: p-T774-PKN1 phosphorylates CDC25C (Schizosaccharomyces pombe)


name: ATP + coproporphyrin I(in) + H2O => ADP + coproporphyrin I(out) + H(+) + phosphate


name: 5'-deoxyadenosine + H(+) + H2O <=> 5'-deoxyinosine + NH4(+)


name: TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Mus musculus)


name: Clathrin recruits PIK3C2A (Gallus gallus)


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + ATP = 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + ADP + H(+)


name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + 1,2-dihexanoylglycerol => 1,2-dihexanoyl-3-(7Z,10Z,13Z-hexadecatrienoyl)-glycerol + CoA


name: Recruitment of ZAP-70 to phosphorylated ITAMs (Gallus gallus)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Bos taurus)


name: RAC2 binds effectors at the mitochondrial outer membrane (Dictyostelium discoideum)


name: Activation of proMMP10 (Canis familiaris)


name: PGAM5 dodecamer dephosphorylates p-S336-ME1 (Sus scrofa)


name: DOLPP1 dephosphorylates DOLDP to DOLP (Gallus gallus)


name: L-rhamnonate <=> 2-dehydro-3-deoxy-L-rhamnonate + H2O


name: Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Gallus gallus)


name: a 1-acyl-sn-glycerol + H2O => a fatty acid + glycerol + H(+)


name: dodecanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression (Danio rerio)


name: (2E)-geranyl diphosphate <=> (Z)-beta-ocimene + diphosphate


name: UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Mus musculus)


name: ATP + H2O + prostaglandin E2(in) <=> ADP + H(+) + phosphate + prostaglandin E2(out)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Homo sapiens)


name: 3,17-didehydrostemmadenine + H2O => akuammicine + formate + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-retinylidene-N-retinylethanolamine => H2O + N-retinylidene-N-retinylphosphatidylethanolamine


name: uridine(65) in tRNA <=> pseudouridine(65) in tRNA


name: a 2'-deoxyguanosine in DNA + methylglyoxal <=> an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA


name: AKT3 phosphorylates TBX3 (Rattus norvegicus)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Drosophila melanogaster)


name: (indol-3-yl)acetonitrile + sulfate + sulfur => (Z)-(indol-3-yl)-N-(sulfonatooxy)methanimidothioate


name: ABC-type L-arabinose transporter activity


name: Defective OPN1SW causes tritanopia (Homo sapiens)


name: SLC43A1 (LAT3)-mediated uptake of large neutral amino acids (Xenopus tropicalis)


name: PEX3:PEX19:class I PMP dissociates (Drosophila melanogaster)


name: ACAD11 dehydrogenates BH-CoA (Canis familiaris)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Mus musculus)


name: Formation of Pol zeta complex (Plasmodium falciparum)


name: 2-oxoglutarate + eicosanoyl-CoA + O2 <=> 2-hydroxyeicosanoyl-CoA + CO2 + succinate


name: an acyl-CoA + zymosterol <=> CoA + zymosterol ester


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Mus musculus)


name: pyridine + thiamine => 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine


name: Recruitment of CAP to ABL (Homo sapiens)


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Mus musculus)


name: Polyubiquitinated RUNX3 translocates to the cytosol (Homo sapiens)


name: P4 bind PGR (in the HSP90 chaperone complex) (Danio rerio)


name: Tankyrase ADP-ribosylates AXIN (Gallus gallus)


name: 3',5'-di-O-methyltricetin + 2 H(+) + 2 S-adenosyl-L-homocysteine => 2 S-adenosyl-L-methionine + tricetin


name: a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose => a globoside GalGb4Cer (d18:1(4E)) + H(+) + UDP


name: a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + diphosphate => a 5'-end diphospho-guanosine in mRNA + GTP + H(+)


name: acetate + H(+) + L,L-cystathionine => L-homocysteine + O-acetyl-L-serine


name: a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+) <=> a very-long-chain 3-oxoacyl-CoA + H(+) + NADH


name: USP33 deubiquitinates CCP110,ARRB (Rattus norvegicus)


name: D-erythrose 4-phosphate + dihydroxyacetone phosphate = D-sedoheptulose 1,7-bisphosphate


name: Loss of Rrn3 from RNA Polymerase I promoter escape complex (Schizosaccharomyces pombe)


name: 4-hydroxybenzaldehyde + CO2 + H2O2 => (S)-4-hydroxymandelate + H(+) + O2


name: OPTN recruits CYLD to the TNFR1 complex (Mus musculus)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Rattus norvegicus)


name: ATP + L-glutamate + L-glutamyl-[protein] => ADP + gamma-L-glutamyl-L-glutamyl-[protein] + H(+) + phosphate


name: CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 (Homo sapiens)


name: Dissociation of CaM and CAMK2 autophosphorylation (Homo sapiens)


name: [protein]-disulfide + phylloquinol <=> [protein]-dithiol + phylloquinone


name: hydrogencarbonate(in) + taurocholate(out) = hydrogencarbonate(out) + taurocholate(in)


name: [L-4-(L-arginin-2-N-yl)aspartate](n) + ATP + L-aspartate => [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + H(+) + phosphate


name: FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis (Homo sapiens)


name: NADP(+) + tetradecasphinganine => 3-oxotetradecasphinganine + H(+) + NADPH


name: carnosine(in) + 2 H(+)(in) => carnosine(out) + 2 H(+)(out)


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Bos taurus)


name: NGF binding to p75NTR inactivates RHOA (Canis familiaris)


name: Translocation of NFATC1:CaN:CaM to nucleus (Sus scrofa)


name: Follitropin is a heterodimer (Danio rerio)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Mus musculus)


name: 2 A + 2 H2O + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] <=> 2 AH2 + 2 formaldehyde + L-lysyl(4)-[histone H3]


name: a (3R)-3-[(carboxymethyl)amino]fatty acid + H(+) + holo-[ACP] <=> a (2E)-enoyl-[ACP] + glycine + H2O


name: (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (22S)-22-hydroxycampest-4-en-3-one + O2 + reduced [NADPH--hemoprotein reductase]


name: NLRP3 activation by small molecules (Bos taurus)


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Bos taurus)


name: Molybdenum ion transfer onto molybdopterin (Dictyostelium discoideum)


name: (3R)-hydroxybutanoyl-[ACP] = (2E)-butenoyl-[ACP] + H2O


name: Pol II elongation complex moves on the template as transcript elongates (Canis familiaris)


name: KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Drosophila melanogaster)


name: Cdh1:APC/C complex binds EHMT1:EHMT2 (Homo sapiens)


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Bos taurus)


name: CoA + H(+) + N-(9Z-octadecanoyl)-dopamine => (9Z)-octadecenoyl-CoA + dopamine


name: L-lysine + 2 S-adenosyl-L-methionine = 2 H(+) + N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine


name: D-galactose + NAD(+) => D-galactono-1,5-lactone + H(+) + NADH


name: alpha-D-glucose 1-phosphate + ATP + H(+) => ADP-alpha-D-glucose + diphosphate


name: Defective ARSB does not hydrolyse C4S/C6S chains (Homo sapiens)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Plasmodium falciparum)


name: P2X7 mediates loss of intracellular K+ (Rattus norvegicus)


name: cis-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O


name: RAB13 GEFs exchange GTP for GDP on RAB13 (Homo sapiens)


name: miR-144 binds to the 3'UTR of the ABCA1 mRNA (Homo sapiens)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Sus scrofa)


name: H2O + O2 + tyramine <=> (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)


name: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2 H(+) + H2O + N-hydroxy-L-isoleucine + oxidized [NADPH--hemoprotein reductase] => L-isoleucine + O2 + reduced [NADPH--hemoprotein reductase]


name: AKR1A1 reduces D-glucuronate to L-gulonate (Canis familiaris)


name: 3-phenylpyruvate + O2 => (2-hydroxyphenyl)acetate + CO2


name: NIPAs transport Mg2+ from extracellular region to cytosol (Gallus gallus)


name: a long-chain alkane + formate + H2O + 2 NADP(+) => a long-chain fatty aldehyde + H(+) + 2 NADPH + O2


name: 4 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) = 4 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: p-Y701-STAT1 dimerizes (Caenorhabditis elegans)


name: p-Y705,S727-STAT3 dimerizes (Xenopus tropicalis)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Bos taurus)


name: MUT isomerises L-MM-CoA to SUCC-CoA (Caenorhabditis elegans)


name: Aquaporin-4 passively transports water out of cell (Canis familiaris)


name: a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O


name: KDSR reduces 3-ketosphingoid (Rattus norvegicus)


name: Defective MMACHC does not reduce Cbl (Homo sapiens)


name: The high affinity receptor complex binds to G-protein (Xenopus tropicalis)


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Canis familiaris)


name: XDH dehydrogenates hypoxanthine to form xanthine (Sus scrofa)


name: deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Sus scrofa)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)


name: TFAP2B homodimer binds YEATS4 (Gallus gallus)


name: 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + S-adenosyl-L-methionine <=> 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + H(+) + S-adenosyl-L-homocysteine


name: RHOA GAPs stimulate RHOA GTPase activity (Canis familiaris)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Schizosaccharomyces pombe)


name: Interaction and oligomerization of MALT1 to Bcl10 (Bos taurus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + octadecanoate


name: dihydroxyacetone phosphate + L-glutamate <=> (S)-serinol phosphate + 2-oxoglutarate


name: Translocation of BMF to mitochondria (Bos taurus)


name: Formation of Cyclin A:Cdc2 complexes (Gallus gallus)


name: glycyl-L-glutamate(out) + 2 H(+)(out) = glycyl-L-glutamate(in) + 2 H(+)(in)


name: cannabigerolate + O2 <=> Delta(9)-tetrahydrocannabinolate + H2O2


name: RAB43:GTP binds USP8NL (Caenorhabditis elegans)


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Canis familiaris)


name: GRB2-1:SOS1 binds p-Y-SHC (Drosophila melanogaster)


name: 4-(gamma-L-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate


name: H(+) + octanoyl-CoA + oxidized [electron-transfer flavoprotein] <=> (2E)-octenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2 acetyl-CoA + 3 H(+) + 6 malonyl-CoA + 2 S-adenosyl-L-methionine = 4-O-demethylbarbatate + 6 CO2 + 8 CoA + H2O + 2 S-adenosyl-L-homocysteine


name: Fibronectin degradation by MMP14 (Sus scrofa)


name: Rho-dependent protein serine/threonine kinase activity


name: Dimerization of DAP12 (Canis familiaris)


name: alpha-D-tagatopyranose 1-phosphate + ATP <=> ADP + D-tagatofuranose 1,6-bisphosphate + H(+)


name: glucose-6-phosphate is converted to inositol-1-phosphate (Mycobacterium tuberculosis)


name: (E,E)-piperate + ATP + H(+) = (E,E)-piperoyl-AMP + diphosphate


name: 3-hydroxybenzyl alcohol + O2 + reduced [NADPH--hemoprotein reductase] = gentisyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O => (9Z,12Z)-octadecadienoate + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H(+)


name: a ganglioside GT1c (d18:1(4E)) + N-acetylneuraminate => a ganglioside GQ1c (d18:1(4E)) + H2O


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Saccharomyces cerevisiae)


name: Formation of Cyclin A:Cdk2 complexes (Homo sapiens)


name: H(+) + N(omega)-(2'-phospho-ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide => L-arginyl-[protein] + NADP(+)


name: D-gluconate + NADP(+) <=> 5-dehydro-D-gluconate + H(+) + NADPH


name: CPN, CPB2 cleave C3a, C5a (Homo sapiens)


name: TLR9 processing at neutral pH (Mus musculus)


name: (20S)-ginsenoside Rg3 + H2O = (20S)-ginsenoside Rh2 + D-glucose


name: IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Gallus gallus)


name: 3,4-dichlorocatechol + O2 = (2Z,4Z)-2,3-dichloromuconate + 2 H(+)


name: n a quinone + n H(+) + n hydrogen sulfide => n a quinol + n sulfur


name: 1-O-alkyl-2-acyl-sn-glycerol + CDP-choline => 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base = a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: 1,3-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-glycerol => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol


name: Cleavage of Procaspase-3 by the apoptosome (Danio rerio)


name: L-threonyl-[protein] + UDP-alpha-D-glucose => 3-O-(alpha-D-glucosyl)-L-threonyl-[protein] + H(+) + UDP


name: Alpha-defensins form biologically active dimers (Rattus norvegicus)


name: PLK3 phosphorylates CDC25C (Homo sapiens)


name: NADPH-dependent dihydrocurcumin reductase activity


name: Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE (Canis familiaris)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(out) + ADP + H(+) + phosphate


name: a 2'-deoxyribonucleoside 5'-phosphate + a 3'-end 2'-deoxyribonucleotide-DNA + H(+) => a 3'-end 2'-deoxyribonucleotidyl-deoxyribonucleotide-DNA + H2O


name: (2S,4S)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine <=> (2S)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: AFG3L2 binds mitochondrial matrix proteins (Sus scrofa)


name: Autocatalytic activation of bound proMMP2 (Rattus norvegicus)


name: 1-O-(trans-sinapoyl)-beta-D-glucose + anthocyanin A8 <=> anthocyanin A11 + D-glucose


name: glutamate-cysteine ligase regulator activity


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Rattus norvegicus)


name: alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose => alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] => an omega-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NIK autophosphorylates on T559 (Gallus gallus)


name: glycine betaine(out) => glycine betaine(in)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + tetradecanoyl-[ACP] = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + holo-[ACP]


name: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoate <=> acetate + vanillin


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = (9Z)-octadecenoate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Homo sapiens)


name: RIP3 binds TRIF to mediate necroptosis (Homo sapiens)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Plasmodium falciparum)


name: cyanurate + H2O <=> 1-carboxybiuret + H(+)


name: 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + H2O + O2 <=> a 2'-deoxycytidine in double-stranded DNA + CO2 + glyoxal + succinate


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Homo sapiens)


name: RHOA:GTP binds ROCK, activating it (Xenopus tropicalis)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Sus scrofa)


name: NFE2L2 dependent ABCC1 expression (Homo sapiens)


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Canis familiaris)


name: (3S)-hydroxy-(5Z-tetradecenoyl)-CoA + NAD(+) <=> 3-oxo-(5Z-tetradecenoyl)-CoA + H(+) + NADH


name: betaenone C + H(+) + NADPH + O2 = H2O + NADP(+) + stemphyloxin I


name: Hemoglobin A binds O2, releasing H+ and CO2 (Xenopus tropicalis)


name: 4beta-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-4beta,26-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: a (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (6Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: GLTP transports GSL from plasma membrane to ER membrane (Danio rerio)


name: PDE6D dissociates from ARL13B:INPP5E (Canis familiaris)


name: ALDHs oxidise atRAL to atRA (Sus scrofa)


name: L-alanine(in) + L-threonine(out) => L-alanine(out) + L-threonine(in)


name: Recognition of AAUAAA sequence by CPSF (Saccharomyces cerevisiae)


name: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Caenorhabditis elegans)


name: gypsogenin + UDP-alpha-D-glucose => gypsogenin 28-beta-D-glucoside + UDP


name: RNASEL cleaves cellular ssRNA (Homo sapiens)


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + testosterone <=> 1alpha-hydroxytestosterone + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Collagen type XV restin release (Gallus gallus)


name: dihydrocarvone + H(+) + NADPH + O2 <=> 4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: ECHS1 hydrates methacrylyl-CoA (Rattus norvegicus)


name: chanoclavine-I aldehyde + H(+) + NADH => chanoclavine-I + NAD(+)


name: S1PR1 binds S1PR1 agonists (Mus musculus)


name: Truncated Alpha-1-Microglobulin binds heme (Mus musculus)


name: [thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]


name: SMURFs ubiquitinate RUNX3 (Homo sapiens)


name: SMURF2 ubiquitinates SMAD2 (Canis familiaris)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Dictyostelium discoideum)


name: 3-oxodecanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxydecanoyl-[ACP] + NADP(+)


name: NAD(+) + resolvin D2 <=> 7-oxoresolvin D2 + H(+) + NADH


name: hydrogen cyanide + piperonal = (2S)-2-(2H-1,3-benzodioxol-5-yl)-2-hydroxyacetonitrile


name: (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+)


name: PELI1 ubiquitinates RIPK3 at K363 (Mus musculus)


name: 5-S-cysteinyldopa + L-dopaquinone <=> 5-S-cysteinyldopaquinone + L-dopa


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Danio rerio)


name: (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] = (+)-6-endo-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: PRKACA phosphorylates TNNI3 (Caenorhabditis elegans)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Canis familiaris)


name: 2'-deoxyadenosine(out) + H(+)(out) => 2'-deoxyadenosine(in) + H(+)(in)


name: acetyl-CoA + L-threonyl-[protein] <=> CoA + O-acetyl-L-threonyl-[protein]


name: a (3R)-3-hydroxyacyl-CoA + NADP(+) = a 3-oxoacyl-CoA + H(+) + NADPH


name: MSH2:MSH6 exchanges ADP for ATP (Schizosaccharomyces pombe)


name: glycine betaine + H(+) + NADH + O2 => formaldehyde + H2O + N,N-dimethylglycine + NAD(+)


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Danio rerio)


name: beta-alaninamide + H2O = beta-alanine + NH4(+)


name: PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Sus scrofa)


name: AH2 + Co(II)-factor III + S-adenosyl-L-methionine => A + Co-precorrin-4 + S-adenosyl-L-homocysteine


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Gallus gallus)


name: ASPA deacetylates NAA to acetate and L-aspartate (Homo sapiens)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Rattus norvegicus)


name: Cdh1:APC/C complex binds EHMT1:EHMT2 (Bos taurus)


name: L-aspartate + NADP(+) = H(+) + iminosuccinate + NADPH


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Caenorhabditis elegans)


name: ATXN3 binds RAD23 (Plasmodium falciparum)


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Sus scrofa)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Sus scrofa)


name: an S-substituted L-cysteine + glycine => an S-substituted L-cysteinylglycine + H2O


name: D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H2O <=> D-glycero-beta-D-manno-heptose 1-phosphate + phosphate


name: SREBP1A,1C,2:Importin beta-1 dissociates (Canis familiaris)


name: Fe(II)2-[transferrin] + H(+) + NAD(+) => Fe(III)2-[transferrin] + NADH


name: Recognition of AAUAAA sequence by CPSF (Bos taurus)


name: ADP + dGMP + H(+) => 2'-deoxyguanosine + ATP


name: dihydrocarveol + NAD(+) = dihydrocarvone + H(+) + NADH


name: transforming growth factor beta receptor activity, type I


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in) => 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out)


name: SUMOylation of TOP2B with SUMO1 (Xenopus tropicalis)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Drosophila melanogaster)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)


name: CoA + H(+) + L-2-aminoadipate + penicillin G => H2O + isopenicillin N + phenylacetyl-CoA


name: Complement factor I binds C4BP (Homo sapiens)


name: acetophenone + hydrogen cyanide => (2S)-2-hydroxy-2-phenylpropanenitrile


name: [phosphate](n) + ADP => [phosphate](n+1) + AMP


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate => an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Gallus gallus)


name: Keratin filaments bind cell-cell adhesion complexes (Xenopus tropicalis)


name: TRAF1 is cleaved by caspases (Bos taurus)


name: LRIG1 undergoes ubiquitination (Homo sapiens)


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Mus musculus)


name: H(+) + N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP => N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: DHAP is converted to G3P by GPD1/GPD1L (Plasmodium falciparum)


name: 2 2-oxoglutarate + 2 O2 + pentalenolactone D <=> 2 CO2 + H2O + pentalenolactone F + 2 succinate


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Rattus norvegicus)


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Rattus norvegicus)


name: 2xTPK1:Mg2+ phosphorylates THMN (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine


name: The high affinity receptor complex binds to G-protein (Homo sapiens)


name: H2O + N-hexanoyl-sphinganine = hexanoate + sphinganine


name: ent-7alpha-hydroxykaur-16-en-19-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => ent-kaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + UDP-alpha-D-glucuronate => an alpha-D-glucuronosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + H(+) + UDP


name: dodecanoate + dodecanoyl-3-beta-D-galactosyl-sn-glycerol + H(+) => 1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol + H2O


name: H(+) + L-aspartate <=> beta-alanine + CO2


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Sus scrofa)


name: an 11-oxosteroid + H(+) + NADH => an 11beta-hydroxysteroid + NAD(+)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Mus musculus)


name: (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + CO2 + CoA


name: KCTD1 binds TFAP2 homo- and heterodimers (Drosophila melanogaster)


name: galactitol + NAD(+) => D-galactose + H(+) + NADH


name: 8 CO2 + 9 CoA + 7 H2O + 13 NADP(+) + wortmanamide B => 5-aminopentanoate + acetyl-CoA + 20 H(+) + 8 malonyl-CoA + 13 NADPH


name: (S)-malate(out) + citrate(in) => (S)-malate(in) + citrate(out)


name: P2X7 mediates membrane pores that include pannexin-1 (Sus scrofa)


name: SUMOylation of NFKB2 with SUMO1 (Sus scrofa)


name: Expression of TBX5 in cardiogenesis (Homo sapiens)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Schizosaccharomyces pombe)


name: AADAC deacetylates PHEN (Canis familiaris)


name: CDK6 inhibitors bind CDK6 (Homo sapiens)


name: 3-methyl-2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 2-methylpropanoyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: ITPA dimer dephosphorylates RBV-TP to RBV-MP (Saccharomyces cerevisiae)


name: FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: L-lysyl-[protein] + tetradecanoyl-CoA <=> CoA + H(+) + N(6)-tetradecanoyl-L-lysyl-[protein]


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Mus musculus)


name: adenosine(out) + Na(+)(out) <=> adenosine(in) + Na(+)(in)


name: PANK4 hydrolyzes PPANT to pantetheine (Caenorhabditis elegans)


name: HTRA1 hydrolyzes ACAN (Aggrecan) (Homo sapiens)


name: Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE (Bos taurus)


name: Conversion of malonyl-CoA and acetyl-CoA to palmitate (Sus scrofa)


name: an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine <=> an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine


name: 10-hydroxy-alpha-humulene + NAD(+) <=> H(+) + NADH + zerumbone


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(N-hexadecanoyl)-ethanolamine + H2O <=> 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: benzoyl-CoA + 2 H(+) + 3 malonyl-CoA = 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA


name: glycodeoxycholate + H2O => deoxycholate + glycine


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Gallus gallus)


name: 3-hydroxy-2-methyl-1H-quinolin-4-one + O2 => CO + H(+) + N-acetylanthranilate


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 11-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-dihexanoylglycerol + octadecanoyl-CoA <=> 1,2-dihexanoyl-3-octadecanoylglycerol + CoA


name: GABA loaded synaptic vesicle Docking and Priming (Canis familiaris)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[12] (Saccharomyces cerevisiae)


name: aniline + N,N-dimethyl-1,4-phenylenediamine + 2 NADP(+) = 4-(dimethylamino)azobenzene + 2 H(+) + 2 NADPH


name: Trehalose-6-phosphate is hydrolyzed to trehalose (Mycobacterium tuberculosis)


name: Epsin family proteins bind ubiquitinated cargo (Homo sapiens)


name: (2S)-2-hydroxy-3,4-dioxopentyl phosphate <=> 3-hydroxy-2,4-dioxopentyl phosphate


name: (9Z)-tetradecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z)-tetradecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2 a phenolic donor + H2O2 => 2 a phenolic radical donor + 2 H2O


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Saccharomyces cerevisiae)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Gallus gallus)


name: 1-decanoylglycerol + H2O <=> decanoate + glycerol + H(+)


name: AOX1 oxidises PXL to PDXate (Sus scrofa)


name: Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen (Mus musculus)


name: 4-methyl-5-oxo-octanedioyl-CoA + acetyl-CoA => 6-methyl-3,7-dioxodecanedioyl-CoA + CoA


name: CYP2W1 oxidises INDOL (Xenopus tropicalis)


name: H(+)(in) + L-alanine(in) = H(+)(out) + L-alanine(out)


name: PDGF dimer binds two receptors simultaneously (Xenopus tropicalis)


name: (+)-pinoresinol + H2O + 2 oxidized [azurin] <=> (+)-6-hydroxypinoresinol + 2 H(+) + 2 reduced [azurin]


name: STAT3 is phosphorylated downstream of active ALK (Rattus norvegicus)


name: UDP-N-acetyl-alpha-D-glucosamine <=> H2O + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose


name: HMIT co-transports myo-inositol with a proton (Mus musculus)


name: cholesterol monooxygenase (side-chain-cleaving) activity


name: Pellino ubiquitinates hp-IRAK1 (Canis familiaris)


name: 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine => 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Danio rerio)


name: fatty aldehyde dehydrogenase (NAD+) activity


name: HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Sus scrofa)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Bos taurus)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Gallus gallus)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Mus musculus)


name: alpha-D-Tyv-(1->3)-alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+) => alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-3,6-dideoxy-alpha-D-mannose


name: 5' to 3' exoribonuclease hydrolyzes decapped mRNA (Homo sapiens)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Xenopus tropicalis)


name: a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GD1alpha + CMP + H(+)


name: HTRA2 degrades APP (Amyloid-beta precursor protein) (Homo sapiens)


name: (2S,3S)-versiconal hemiacetal acetate + H2O <=> (2S-3S)-versiconal hemiacetal + acetate + H(+)


name: 8 H(+) + holo-[ACP] + 8 malonyl-CoA => atrochrysone carboxyl-[ACP] + 8 CO2 + 8 CoA + 2 H2O


name: Digestion of triacylglycerols by extracellular PTL:colipase (Mus musculus)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Homo sapiens)


name: a (2R)-2-hydroxycarboxylate + NADP(+) <=> a 2-oxocarboxylate + H(+) + NADPH


name: 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: AKT2 binds PIP3 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol => a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Rattus norvegicus)


name: 2 ATP + 2 cob(II)inamide + 2 H2O + reduced [electron-transfer flavoprotein] => 2 adenosylcob(III)inamide + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate


name: Caspase-mediated cleavage of Lamin A (Gallus gallus)


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(in) + ATP + H2O = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(out) + ADP + H(+) + phosphate


name: ATP + D-hamamelose => ADP + D-hamamelose 2'-phosphate + H(+)


name: EXT1:EXT2 transfers GlcA to heparan (Drosophila melanogaster)


name: Vanin hydrolyses pantetheine to PanK, 2AET (Homo sapiens)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Canis familiaris)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Rattus norvegicus)


name: glutathione disulfide + H2O2 => 2 glutathione + O2


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O <=> an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + N-acetyl-D-galactosamine


name: Factor D cleaves C3b-bound Factor B (Gallus gallus)


name: 15-cis-phytoene + 3 A => 3 AH2 + all-trans-neurosporene


name: (3R)-hydroxy-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA <=> (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H2O


name: DIBOA beta-D-glucoside + H2O <=> D-glucose + DIBOA


name: luteolin + S-adenosyl-L-methionine <=> diosmetin + H(+) + S-adenosyl-L-homocysteine


name: Fillagrin and keratin intermediate filaments polymerize forming a network (Danio rerio)


name: 3-phosphoinositide-dependent protein kinase binding


name: SGMS2 transfers phosphocholine onto ceramide (Mus musculus)


name: dimethylallyl diphosphate + preechinulin = diphosphate + tardioxopiperazine A


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O => 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: TP53 stimulates expression of the TP53I3 (PIG3) gene (Homo sapiens)


name: 2-methylbutyl acetate + CoA => 2-methylbutan-1-ol + acetyl-CoA


name: (E)-4-hydroxyphenylacetaldehyde oxime => (Z)-(4-hydroxyphenyl)acetaldehyde oxime


name: chloride(out) + L-asparagine(out) + 2 Na(+)(out) <=> chloride(in) + L-asparagine(in) + 2 Na(+)(in)


name: chloride(out) + L-alanine(out) + 2 Na(+)(out) = chloride(in) + L-alanine(in) + 2 Na(+)(in)


name: Caspase-mediated cleavage of Lamin B1 (Canis familiaris)


name: Interaction of particulate antigens with dendritic cell receptors (Drosophila melanogaster)


name: Retrograde COPI vesicles bind kinesin and microtubules (Mus musculus)


name: oxidoreductase activity, acting on metal ions, flavin as acceptor


name: ATP + CoA + nicotinate = AMP + diphosphate + nicotinyl-CoA


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Xenopus tropicalis)


name: XIAP dissociates from ub-TLE (Canis familiaris)


name: cyathadiol + O2 + reduced [NADPH--hemoprotein reductase] => cyathatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3,17-didehydrostemmadenine + H2O + NADPH <=> (16S)-deshydroxymethyl-stemmadenine + formate + NADP(+)


name: (6S)-5,6,7,8-tetrahydropteroate + NAD(+) <=> 7,8-dihydropteroate + H(+) + NADH


name: (R)-4'-phosphopantetheine sulfonate + H2O <=> (R)-pantetheine sulfonate + phosphate


name: 4alpha-methyl-5alpha-cholest-8-en-3-one + H(+) + NADPH = 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+)


name: SEMA3E binds to PLXND1 (Xenopus tropicalis)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)


name: RHOC activates endoplasmic reticulum effectors (Saccharomyces cerevisiae)


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Homo sapiens)


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Sus scrofa)


name: 2,4-dichlorophenol + CO2 + pyruvate + succinate => (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2


name: ITGA4:ITGB1 binds natalizumab (Caenorhabditis elegans)


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Mus musculus)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Mus musculus)


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Sus scrofa)


name: F2R binds ARRB1 (Caenorhabditis elegans)


name: TBC1D7 binds the TSC1-TSC2 complex (Xenopus tropicalis)


name: SLCO3A1 isoform 1 has abroad substrate specificity (Homo sapiens)


name: COX10 transforms heme to heme O (Caenorhabditis elegans)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Mus musculus)


name: 9-decenoyl-CoA + 3 H(+) + 3 malonyl-CoA => 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one + 3 CO2 + 4 CoA


name: 2-aminomuconate 6-semialdehyde + CO2 => 2-amino-3-carboxymuconate 6-semialdehyde + H(+)


name: PLG(20-810) binds anti-fibrinolytics (Gallus gallus)


name: PMM1,2 isomerise Man6P to Man1P (Homo sapiens)


name: ATP + H2O + L-alanyl-L-histidine(out) => ADP + H(+) + L-alanyl-L-histidine(in) + phosphate


name: Dephosphorylation of TYK2 by PTP1B (Mus musculus)


name: L-isoleucine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (1E,2S)-2-methylbutanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of TBK1/IKBKE (Homo sapiens)


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Bos taurus)


name: USP9X binds Ub:PEX5L (Caenorhabditis elegans)


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: H(+) + sulfite + UDP-alpha-D-glucose => H2O + UDP-alpha-D-6-sulfoquinovose


name: FVIIIa variant:FIXa does not convert FX to the active FXa (Homo sapiens)


name: RHOA:GTP:RTKN binds LIN7B (Canis familiaris)


name: butan-2-one + hydrogen cyanide => (2R)-2-hydroxy-2-methylbutanenitrile


name: a 3beta-hydroxysteroid + a triacylglycerol => a 3beta-hydroxysteroid ester + a diacylglycerol


name: CYP3A4,5 hydroxylates AFB1 to AFQ1 (Homo sapiens)


name: nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Mus musculus)


name: Association of Securin with Cdc20:APC/C complex (Bos taurus)


name: 2-oxoglutarate + H(+) + NADPH + NH4(+) => H2O + L-glutamate + NADP(+)


name: (1R,2R,4S)-limonene-1,2-diol + NAD(+) = (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADH


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Caenorhabditis elegans)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Mus musculus)


name: but-3-ynal + H2O + NAD(+) <=> 3-butynoate + 2 H(+) + NADH


name: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil


name: (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 = (E)-2,4-dihydroxycinnamoyl-CoA + CO2 + succinate


name: aurachin C + H(+) + NADH + O2 = aurachin C epoxide + H2O + NAD(+)


name: Constitutive phosphorylation by GSK3 (Mus musculus)


name: 2-acetylphloroglucinol + 3 CO2 + 4 CoA => acetyl-CoA + 3 H(+) + 3 malonyl-CoA


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate <=> 5-epi-alpha-selinene + diphosphate


name: GLYAT-like proteins transfer glycine to ST-CoA to form SUA (Canis familiaris)


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Sus scrofa)


name: (3E)-nonen-2-one + H(+) + NADPH => NADP(+) + nonan-2-one


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Danio rerio)


name: 3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O


name: formononetin + O2 + reduced [NADPH--hemoprotein reductase] <=> calycosin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-phenylpropanal + hydrogen cyanide = (2S)-2-hydroxy-4-phenylbutanenitrile


name: MRN bound to shortened telomeres activates ATM (Saccharomyces cerevisiae)


name: (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NADP(+) => 4-methylsulfanyl-2-oxobutanoate + H(+) + NADPH


name: ABCA12 transports lipids from cytosol to extracellular region (Homo sapiens)


name: 1,4-cineole + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-exo-hydroxy-1,4-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Drosophila melanogaster)


name: (2E)-geranyl diphosphate = alpha-terpinene + diphosphate


name: (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate


name: 2-oxoglutarate + fumigatonoid C + O2 => CO2 + H2O + novofumigatonin + succinate


name: Iodide is taken up by thyroid epithelial cells (Xenopus tropicalis)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Homo sapiens)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Mus musculus)


name: WWTR1 (TAZ) binds ZO-2 (TJP2) (Gallus gallus)


name: SN-38 + UDP-alpha-D-glucuronate <=> H(+) + SN-38 O-beta-D-glucuronide + UDP


name: beta-NGF dimer binds to TrkA receptor (Xenopus tropicalis)


name: Expression of DLX5 in the neural plate border (Homo sapiens)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Sus scrofa)


name: H2O + lactobiono-1,5-lactone = H(+) + lactobionate


name: Fe(2+)(in) + 2 hydrogencarbonate(in) => Fe(2+)(out) + 2 hydrogencarbonate(out)


name: IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Mus musculus)


name: cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Rattus norvegicus)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + soppiline B = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + soppiline C


name: a 1-acyl-sn-glycero-3-phosphate + octadecanoyl-CoA <=> a 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: repressor of RNA polymerase inhibitor activity


name: 1,2-diacyl-3-O-[alpha-D-glucosyl-(1-> 2)-alpha-D-glucosyl]-sn-glycerol + H(+) + UDP => a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose


name: (5Z,8Z)-eicosadienoate + O2 <=> (5S)-hydroperoxy-(6E,8Z)-eicosadienoate


name: (9Z)-octadecenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoA


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Schizosaccharomyces pombe)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine => a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP


name: Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1 (Homo sapiens)


name: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Xenopus tropicalis)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + ethanolamine + H(+) => 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O


name: Mutant RAS:p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Saccharomyces cerevisiae)


name: Formation of the 'destruction complex' (Drosophila melanogaster)


name: H2O + S-formylglutathione => formate + glutathione + H(+)


name: (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(2'-(9Z-octadecenoyl)-3'-sn-glycerol) + H2O => (9Z)-octadecenoate + (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-sn-glycerol) + H(+)


name: RIPPLY2 binds TBX6 and recruits the 26S proteasome (Homo sapiens)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Bos taurus)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Bos taurus)


name: COASY phosphorylates DP-CoA (Caenorhabditis elegans)


name: "With NADH or NADPH as one donor, and incorporation of one atom of oxygen"


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Homo sapiens)


name: beta-alanine(out) + chloride(out) + 2 Na(+)(out) => beta-alanine(in) + chloride(in) + 2 Na(+)(in)


name: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine


name: H(+) + NADPH + UDP-4-dehydro-beta-L-rhamnose => NADP(+) + UDP-beta-L-rhamnose


name: Formation of the MLL2 complex (Homo sapiens)


name: 1,2-dihexanoyl-3-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1,2-dihexanoylglycerol