name: 2-oxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] => 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin


name: D-xylulose + H(+) + NADPH => D-arabinitol + NADP(+)


name: 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA => 16-hydroxyhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: acetyl phosphate + L-lysine => H(+) + N(6)-acetyl-L-lysine + phosphate


name: GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Xenopus tropicalis)


name: 7-dehydrodesmosterol + H(+) + NADPH = desmosterol + NADP(+)


name: Activation of Ca permeable AMPA receptors (Drosophila melanogaster)


name: acetyl-CoA + chloramphenicol <=> chloramphenicol 3-acetate + CoA


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Bos taurus)


name: WNTs bind the FZD receptor to initiate PCP pathway (Homo sapiens)


name: ATP + citrate + spermidine = AMP + diphosphate + H(+) + N(8)-citryl-spermidine


name: PTK6 phosphorylates CDKN1B (Xenopus tropicalis)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Caenorhabditis elegans)


name: LYZ binds bacterial peptidoglycan (Bos taurus)


name: 9-cis-retinol + hexadecanoyl-CoA => 9-cis-retinyl hexadecanoate + CoA


name: ATP + D-alanine + holo-[D-alanyl-carrier protein] => AMP + D-alanyl-[D-alanyl-carrier protein] + diphosphate


name: AKR1B15 reduces EST17b to E1 (Xenopus tropicalis)


name: AKT1 binds eNOS complex via HSP90 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O <=> a 1-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: RHOBTB3 hydrolyzes ATP (Dictyostelium discoideum)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Danio rerio)


name: 2-oxoglutarate + 2 H(+) + NH4(+) + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + L-glutamate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: BESTs transport cytosolic HCO3- to extracellular region (Xenopus tropicalis)


name: PAOX:FAD oxidises NASPN to SPM (Danio rerio)


name: 1D-3-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine => myo-inositol + S-adenosyl-L-methionine


name: Plasmin proteolyzes IGF:IGFBP-3:ALS (Rattus norvegicus)


name: Caspase 3-mediated cleavage of DFF45 (117) (Canis familiaris)


name: DNA polymerase alpha:primase binds at the origin (Sus scrofa)


name: H2O + NADP(+) + nicotinate => 6-hydroxynicotinate + H(+) + NADPH


name: p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane (Canis familiaris)


name: calcitetrol + H2O + 2 oxidized [adrenodoxin] => 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol


name: p-S158,221-HuR binds mRNA (Mus musculus)


name: MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Gallus gallus)


name: 2-oxoglutarate + dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose => dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + L-glutamate


name: PTPS is phosphorylated by cGMP-dependant protein kinase II (Homo sapiens)


name: Beta-catenin is released from the destruction complex (Sus scrofa)


name: 5-methyldeoxycytidine diphosphate + ADP => 5-methyldeoxycytidine 5'-phosphate + ATP


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] = H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein]


name: an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => an N-acylsphing-14Z-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Homo sapiens)


name: 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Canis familiaris)


name: an N-acylsphing-4-enine + UDP-alpha-D-glucose => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) => a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in)


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Drosophila melanogaster)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Caenorhabditis elegans)


name: GSK3B phosphorylates p-NFE2L2 (Homo sapiens)


name: Phosphorylation of MEK4 by MEKK1 (Rattus norvegicus)


name: Expression of POU5F1 (OCT4) in primordial germ cells (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in)


name: Elastin cross-linking by lysyl oxidase (Rattus norvegicus)


name: Re-integration of insulin receptor into plasma membrane (Caenorhabditis elegans)


name: D-glucose(in) + Na(+)(in) => D-glucose(out) + Na(+)(out)


name: FKBP1A binds sirolimus (Rattus norvegicus)


name: 2-oxoadipate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] = CO2 + N(6)-[(R)-S(8)-glutaryldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase]


name: SHC1 bound to the common beta chain becomes tyrosine phosphorylated (Homo sapiens)


name: SUMOylation of Histone H4 with SUMO3 (Dictyostelium discoideum)


name: Recruitment of ERCC6 (CSB), EHMT2 (G9a), and NuRD to the promoter of rRNA gene (Homo sapiens)


name: ADP + bacteriochlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate = 3-acetyl-3-devinylchlorophyllide a + ATP + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin]


name: p-Y705-STAT3 binds p-Y693-STAT4 (Xenopus tropicalis)


name: D-sorbitol + O2 = D-sorbopyranose + H2O2


name: a 1-acyl-sn-glycero-3-phosphate + ADP + H(+) => a 1-acyl-sn-glycerol + ATP


name: SULTs transfer (SO4)2- group to PREG (Canis familiaris)


name: chloride(out) + glycine(out) + 2 Na(+)(out) => chloride(in) + glycine(in) + 2 Na(+)(in)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Homo sapiens)


name: N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-taurine => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Rattus norvegicus)


name: dAMP(out) + phosphate(in) => dAMP(in) + phosphate(out)


name: 2 alpha-D-glucose 1-phosphate + H2O = D-maltose + 2 phosphate


name: PXLP-K333-GADL1 decarboxylates acidic AAs (Bos taurus)


name: 2-amino-2-deoxy-D-gluconate 6-phosphate(in) + L-histidyl-[protein] => 2-amino-2-deoxy-D-gluconate(out) + N(pros)-phospho-L-histidyl-[protein]


name: epothilone A + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => epothilone C + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: testosterone + UDP-alpha-D-glucuronate = H(+) + testosterone 17-O-(beta-D-glucuronate) + UDP


name: 1D-myo-inositol 2,3-bisphosphate + phosphate => 1D-myo-inositol 1,2,3-trisphosphate + H2O


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphate = a 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: H2O + L-arginine => L-citrulline + NH4(+)


name: MASTL phosphorylates ENSA (Homo sapiens)


name: dihydrozeatin UDP glycosyltransferase activity


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Xenopus tropicalis)


name: Formation of MHC II alpha beta heterodimer (Danio rerio)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Dictyostelium discoideum)


name: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O => a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol


name: NADP(+) + prostaglandin F2alpha => H(+) + NADPH + prostaglandin D2


name: 2 Na(+)(out) + nicotinate(out) = 2 Na(+)(in) + nicotinate(in)


name: H(+) + H2O + N-benzyloxycarbonylglycine => benzyl alcohol + CO2 + glycine


name: The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)


name: PLA2G2A binds bacterial phospholipids (Rattus norvegicus)


name: (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Homo sapiens)


name: 5-phosphomethyl-dUMP in DNA + L-serine => 5-O-(L-seryl)-dTMP in DNA + phosphate


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-hexacosanoyl-(4R)-hydroxysphinganine + O2 = 2 Fe(III)-[cytochrome b5] + H2O + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: Formation of the MCC complex (Drosophila melanogaster)


name: SRC-1 phosphorylates PTK2-beta (Bos taurus)


name: H2O + N,1-diacyl-sn-glycero-3-phosphoethanolamine => a fatty acid + H(+) + N-acyl-sn-glycero-3-phosphoethanolamine


name: Vamp7 associated Lysosome to Plasma membrane transport (Xenopus tropicalis)


name: cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine = aminopropylcadaverine + H(+) + S-methyl-5'-thioadenosine


name: 3-hydroxytetradecanoate + ATP + CoA => 3-hydroxytetradecanoyl-CoA + AMP + diphosphate


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Rattus norvegicus)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Xenopus tropicalis)


name: Cleaved KMT2A dimers translocate to the nucleus (Drosophila melanogaster)


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Schizosaccharomyces pombe)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Sus scrofa)


name: ADP + H(+) + L-fuculose 1-phosphate => ATP + L-fuculose


name: eNOS associates with Caveolin-1 (Sus scrofa)


name: (R)-carnitine(in) + O-propanoyl-(R)-carnitine(out) => (R)-carnitine(out) + O-propanoyl-(R)-carnitine(in)


name: 2 H(+) + isoproturon + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 1-methyl-3-[4-(propan-2-yl)phenyl]urea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Lsm1-7 Complex binds deadenylated mRNA (Gallus gallus)


name: dehydro-D-arabinono-1,4-lactone + H(+) + H2O2 => D-arabinono-1,4-lactone + O2


name: alpha-secretase cleaves the p75NTR extracellular domain (Canis familiaris)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Canis familiaris)


name: Dicer cleaves pre-miRNA to yield duplex miRNA (Homo sapiens)


name: DLST transfers succinyl to CoA (Rattus norvegicus)


name: CRLF1:CLCF1 binds CNTRF (Canis familiaris)


name: Type II receptor phosphorylates type I receptor (Sus scrofa)


name: CSF1R trans-autophosphorylates on tyrosine-561 (Homo sapiens)


name: RAD51B:RAD51C binds single-stranded DNA (Gallus gallus)


name: 11-deoxycortisol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => cortisol + H2O + 2 oxidized [adrenodoxin]


name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate (Homo sapiens)


name: (S)-alpha-hydroxyglutarate-gamma-lactone + H2O <=> 2-hydroxyglutarate + H(+)


name: ILK interacts with beta-1 integrin (Rattus norvegicus)


name: calcium,diacylglycerol-dependent serine/threonine kinase activity


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate + 6-hydroxymellein => diphosphate + verruculide C


name: H2O + triphosphate => diphosphate + phosphate


name: PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 (Homo sapiens)


name: an NDP-alpha-D-glucose + D-fructose <=> a ribonucleoside 5'-diphosphate + H(+) + sucrose


name: 1D-myo-inositol 3-phosphate + CDP-2,3-bis-O-(phytanyl)-sn-glycerol => CMP + H(+) + saturated 1-archaetidyl-1D-myo-inositol 3-phosphate


name: a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + L-histidyl-[RNA ligase] => a 3'-end 3'-phospho-ribonucleotide-RNA + H(+) + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase]


name: acetyl-CoA + N-terminal L-methionyl-L-asparaginyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-asparaginyl-[protein]


name: Translocation of Cdc25 to the nucleus (Homo sapiens)


name: fumarate(out) + 3 Na(+)(out) <=> fumarate(in) + 3 Na(+)(in)


name: AKT interacts and phosphorylates Cot (Gallus gallus)


name: CYP3A4 oxidizes PREDN,PREDL (Xenopus tropicalis)


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Danio rerio)


name: a 2-acylglycerol + hexadecanoyl-CoA => a 1-hexadecanoyl-2-acylglycerol + CoA


name: platelet-derived growth factor beta-receptor activity


name: Formation of pre-mRNPs (Dictyostelium discoideum)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Xenopus tropicalis)


name: Activated TP receptor binds G-proten Gq (Sus scrofa)


name: a 1,2-diacyl-sn-glycerol + CDP-ethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: MDH2 dimer dehydrogenates MAL (Mus musculus)


name: Caspase-mediated cleavage of plakophilin-1 (Bos taurus)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate <=> 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: ATG12 forms a thioester bond with ATG7 dimer (Saccharomyces cerevisiae)


name: 4-methyl-2-oxopentanoate + H2O2 + NH4(+) => H2O + L-leucine + O2


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Sus scrofa)


name: ATXN3 binds VCP (Caenorhabditis elegans)


name: a 7(1),7(1)-dihydroxybacteriochlorophyllide d <=> a bacteriochlorophyllide f + H2O


name: (20S)-ginsenoside Rb2 + 2 H2O <=> (20S)-ginsenoside C-Y + 2 D-glucose


name: (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H(+) + NADPH <=> (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: CYP2A13 oxidises AFM1 to AFM1E (Bos taurus)


name: Multiubiquitination of APC/C-associated Cdh1 (Mus musculus)


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Drosophila melanogaster)


name: AMP + guanosine 3',5'-bis(diphosphate) => ATP + GDP


name: Hydrolysis of PC to PA by PLD (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (2E,6E)-farnesyl phosphate + H(+) + phosphate


name: coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2


name: "coproporphyrinogen III oxidase (coproporphyrin-forming)"


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Bos taurus)


name: 3-oxochol-4-en-22-oyl-CoA + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochol-4-en-22-oyl-CoA + H2O + NAD(+)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Homo sapiens)


name: MAOA inhibitors bind MAOA:FAD (Dictyostelium discoideum)


name: a bacteriochlorophyllide c + H2O + S-adenosyl-L-methionine = 5'-deoxyadenosine + a 7(1)-hydroxybacteriochlorophyllide c + H(+) + L-methionine


name: 6-deoxy-6-sulfo-D-fructose 1-phosphate = (2S)-3-sulfolactaldehyde + dihydroxyacetone phosphate


name: MDM2 translocates to the nucleus (Danio rerio)


name: Active FLT3 dimer binds GRB2 (Homo sapiens)


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Rattus norvegicus)


name: 1,4-benzoquinone + H(+) + NADH = hydroquinone + NAD(+)


name: E2F1 binds the CDK1 gene promoter (Homo sapiens)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Bos taurus)


name: MRSBs reduce L-methyl-(R)-S-oxide to L-methionine (Homo sapiens)


name: CDC42 binds effectors at the plasma membrane (Canis familiaris)


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Mus musculus)


name: acetyl-CoA + alpha-D-glucosamine 1-phosphate <=> CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate


name: RPA binds to the Flap on the C-strand (Rattus norvegicus)


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Gallus gallus)


name: phosphate + validoxylamine A => H2O + validoxylamine A 7'-phosphate


name: Association of procollagen type XXVII (Danio rerio)


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Drosophila melanogaster)


name: Orexin 1 receptor can bind orexin-A neuropeptide (Canis familiaris)


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Sus scrofa)


name: ARHGAP35 binds RHOA:GTP (Xenopus tropicalis)


name: USP17 deubiquitinates SUDS3 (Drosophila melanogaster)


name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Rattus norvegicus)


name: demethylsuberosin + O2 + reduced [NADPH--hemoprotein reductase] => (7S)-marmesin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Mus musculus)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA = a cardiolipin + CoA


name: H(+) + hexadecanoyl-[ACP] + malonyl-[ACP] <=> 3-oxooctadecanoyl-[ACP] + CO2 + holo-[ACP]


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Rattus norvegicus)


name: glutarate(out) + prostaglandin E2(in) => glutarate(in) + prostaglandin E2(out)


name: (2E,6E)-farnesyl diphosphate = alpha-guaiene + diphosphate


name: a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Sus scrofa)


name: OPN1SW binds 11cRAL (Caenorhabditis elegans)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Rattus norvegicus)


name: NAD(+) + phylloquinol => H(+) + NADH + phylloquinone


name: Autocatalytic activation of MMP1 (Gallus gallus)


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Mus musculus)


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Caenorhabditis elegans)


name: H(+) + N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine => L-lysyl-[citrate synthase] + S-adenosyl-L-methionine


name: L-iditol + NAD(+) <=> H(+) + keto-L-sorbose + NADH


name: diphosphate + tricyclene => (2E)-geranyl diphosphate


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Homo sapiens)


name: P4 bind PGR (in the HSP90 chaperone complex) (Rattus norvegicus)


name: 3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + H(+) + L-alanine


name: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)


name: H2O + N-acetylputrescine = acetate + putrescine


name: Interaction of SIGLEC14/15/16 and DAP12 (Rattus norvegicus)


name: HGSNAT oligomer acetylates Heparan chain(1) (Bos taurus)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)


name: p190RhoGAP binds Plexin-B1 (Danio rerio)


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+)(out) + L-tyrosylglycine(out) => H(+)(in) + L-tyrosylglycine(in)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycerol = 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: H(+) + isonocardicin A + S-methyl-5'-thioadenosine => nocardicin E + S-adenosyl-L-methionine


name: TRAF6 binding to IRAK2 stimulates its oligomerizartion upon TLR7 or TLR21 stimulation (Gallus gallus)


name: Exocytosis of ficolin-rich granule membrane proteins (Xenopus tropicalis)


name: trans-Golgi Network Lysosomal Vesicle Scission (Canis familiaris)


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Mus musculus)


name: cis,cis-muconate + 2 H(+) => catechol + O2


name: p-Y-STAT1,3,5 dimer enhances expression of SOCS3 (Homo sapiens)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Bos taurus)


name: factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) (Gallus gallus)


name: beta-D-GalNAc-(1->4)-alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + H2O => alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + N-acetyl-D-galactosamine


name: Furin cleaves pro-factor X to factor X (Mus musculus)


name: SCF:FBXL7 binds AURKA (Xenopus tropicalis)


name: p-4Y-PLCG1 dissociates from activated FGFR3 (Bos taurus)


name: MDM2 polyubiquitinates RUNX3 (Danio rerio)


name: PTPN6 dephosphorylates JAK3 (Mus musculus)


name: a 5'-end FAD-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + FAD + H(+)


name: ADP + fluconazole(out) + H(+) + phosphate => ATP + fluconazole(in) + H2O


name: IL34 dimer binds CSF1R (Rattus norvegicus)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Bos taurus)


name: factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain (Gallus gallus)


name: LDH tetramer reduces PYR to LACT (Drosophila melanogaster)


name: NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)


name: Active ALK phosphorylates JAK3 (Mus musculus)


name: IGFBP6 binds IGF forming IGF:IGFBP6 (Rattus norvegicus)


name: Nuclear DUSPs dephosphorylate MAPKs (Homo sapiens)


name: cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + H2O = (S)-2-hydroxypropylphosphonate + CMP + H(+)


name: ACSF2 ligates CoA-SH to MCFA (Danio rerio)


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Homo sapiens)


name: pancreatic polypeptide receptor activity


name: Uracil glycosylase mediated recognition and binding of uracil opposite guanine (Gallus gallus)


name: (E)-non-2-enal + H2O + NADP(+) = (E)-non-2-enoate + 2 H(+) + NADPH


name: USP17 deubiquitinates SUDS3 (Bos taurus)


name: allodeoxycholoyl-CoA + cholate <=> allodeoxycholate + choloyl-CoA


name: ADP + all-trans-hexaprenyl phosphate + H(+) => all-trans-hexaprenol + ATP


name: (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase] => 3-dehydro-6-deoxoteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Rattus norvegicus)


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Xenopus tropicalis)


name: NF-kappaB translocates from the cytosol to the nucleus (Canis familiaris)


name: glyoxylate + L-glutamine => 2-oxoglutaramate + glycine


name: a ganglioside Ac-O-7-GT3 = a ganglioside Ac-O-8-GT3


name: S-adenosyl-L-methionine + salicylate = methyl salicylate + S-adenosyl-L-homocysteine


name: Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol (Danio rerio)


name: 2 A + hydroxylamine + NH4(+) => 2 AH2 + H(+) + H2O + N2


name: 3,4-dihydroxybenzaldehyde + acetyl-CoA => (E)-caffeoyl-CoA + H2O


name: choline + H2O + 2 O2 <=> glycine betaine + H(+) + 2 H2O2


name: protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity


name: (d)AMP + ATP <=> (d)ADP + ADP (AK1) (Homo sapiens)


name: H(+) + NADH + O2 + phenol <=> H2O + hydroquinone + NAD(+)


name: (11R)-methyl carlactonoate + 2-oxoglutarate + O2 => (11R)-hydroxymethyl carlactonoate + CO2 + succinate


name: allocholate + allodeoxycholoyl-CoA <=> allocholoyl-CoA + allodeoxycholate


name: ISGylation of host proteins (Caenorhabditis elegans)


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Mus musculus)


name: 4-hydroxyestrone + UDP-alpha-D-glucuronate => 4-hydroxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: SGSH hydrolyses Heparan sulfate chain(7) (Sus scrofa)


name: 4 monapinone E + O2 => 2 dinapinone E + 2 H2O


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Gallus gallus)


name: NRXNs bind CASK:Protein 4.1 (Mus musculus)


name: H(+) + N-(15Z-tetracosenoyl)-sphing-4-enine + phosphocholine => H2O + N-(15Z-tetracosenoyl)sphing-4-enine-1-phosphocholine


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Bos taurus)


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Homo sapiens)


name: 2alpha,7beta-dihydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2alpha-hydroxytaxusin + O2 + reduced [NADPH--hemoprotein reductase]


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Sus scrofa)


name: HPDL dioxygenates HPPA (Dictyostelium discoideum)


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Mus musculus)


name: GTP-bound RAC contributes to JNK activation (Gallus gallus)


name: The receptor is activated (Homo sapiens)


name: alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-6S-D-GlcNAc + CMP + H(+) => alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-6S-D-GlcNAc + CMP-N-acetyl-beta-neuraminate


name: Rag dimer formation (Schizosaccharomyces pombe)


name: Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Xenopus tropicalis)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Sus scrofa)


name: 2 a plastoquinone + 2 H2O + 4 hnu = 2 a plastoquinol + O2


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: dimethyl sulfide + H(+) + NADH + O2 => dimethyl sulfoxide + H2O + NAD(+)


name: Plasma membrane resorption (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O


name: SLC25A10 mediates exchange of malate and phosphate (Danio rerio)


name: 2-hydroxybenzoyl-CoA + malonyl-CoA <=> 4-hydroxycoumarin + CO2 + 2 CoA


name: Adenylate cyclase converts ATP into cyclic AMP (Gallus gallus)


name: PKCdelta phosphorylates HuR (Mus musculus)


name: dimethylallyl diphosphate + H2O => dimethylallyl phosphate + H(+) + phosphate


name: Formation of Cyclin B:Cdc2 complexes (Danio rerio)


name: molybdenum cofactor guanylyltransferase activity


name: Exocytosis of Proactivator polypeptide (Caenorhabditis elegans)


name: dimethylallyl diphosphate + L-tryptophan = 7-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: RUNX2:CBFB binds the MMP13 gene promoter (Homo sapiens)


name: CYP3A4 binds CYP3A4 inhibitors (Canis familiaris)


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Gallus gallus)


name: H2O + NAD(+) + precorrin-3B => 2 H(+) + NADH + O2 + precorrin-3A


name: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-apiose <=> 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + H(+) + UDP


name: Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Homo sapiens)


name: 3-demethylubiquinol-10 + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + ubiquinol-10


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: NADP(+) + prostaglandin F2alpha = H(+) + NADPH + prostaglandin H2


name: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = 4-carboxy-2-hydroxy-cis,cis-muconate + H2O


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-octanoylsphinganine + O2 = 2 Fe(III)-[cytochrome b5] + H2O + N-octanoyl-4-hydroxysphinganine


name: H(+) + oxidized [electron-transfer flavoprotein] + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: Arachidonic acid is converted to HXA3/B3 by ALOX12 (Danio rerio)


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Mus musculus)


name: Transport of fringe-modified NOTCH to plasma membrane (Xenopus tropicalis)


name: IDO2 dioxygenates L-Trp to NFK (Homo sapiens)


name: (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H(+) + NADH => (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+)


name: 6-O-acetyl-beta-D-glucose + CoA => acetyl-CoA + beta-D-glucose


name: HSP90AA1 binds p-6Y-VEGFR2 (Rattus norvegicus)


name: SUMOylation of EP300 with SUMO1 (Sus scrofa)


name: 3,6-anhydro-alpha-L-galactopyranose + H2O + NADP(+) <=> 3,6-anhydro-L-galactonate + 2 H(+) + NADPH


name: MVD decarboxylates MVA5PP to IPPP (Drosophila melanogaster)


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: CYP39A1 7-hydroxylates 24OH-CHOL (Canis familiaris)


name: AKT phosphorylates FOXO1A (Caenorhabditis elegans)


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Caenorhabditis elegans)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: AFG3L2 binds mitochondrial matrix proteins (Drosophila melanogaster)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Homo sapiens)


name: 2-oxoglutarate + a (2S)-flavan-4-one + O2 => a (2R,3R)-dihydroflavonol + CO2 + succinate


name: sGC stimulators bind sGC:NO (Homo sapiens)


name: bunolol + H(+) + NADPH => dihydrobunolol + NADP(+)


name: GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Caenorhabditis elegans)


name: ABCC5 transports TPMP substrates from cytosol to extracellular region (Sus scrofa)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Schizosaccharomyces pombe)


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate <=> (2R)-3-phosphoglycerate + alpha-D-glucose 1,6-bisphosphate + H(+)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Gallus gallus)


name: a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GT1a (d18:1(4E)) + CMP + H(+)


name: A + peniprequinolone <=> AH2 + yaequinolone E


name: Activation of PP2A by Xylulose-5-phosphate (Homo sapiens)


name: 3''-dehydroorientin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: GOT2 transaminates OA and L-Glu (Rattus norvegicus)


name: (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + CO2 + CoA


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose <=> a neolactoside V(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: Budding of COPII coated vesicle (Bos taurus)


name: AKR1B15 reduces EST17b to E1 (Saccharomyces cerevisiae)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Rattus norvegicus)


name: SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Dictyostelium discoideum)


name: Translocation of PDK1 to Plasma membrane (Bos taurus)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Bos taurus)


name: KDM5A-D demethylate Me3K5-histone H3 (Schizosaccharomyces pombe)


name: SARS-CoV-2 8:class I MHC binds BECN1 (Homo sapiens)


name: a ganglioside GT2 (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GT1c (d18:1(4E)) + H(+) + UDP


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Canis familiaris)


name: FMNH2 + N-methylnicotinate + O2 => (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+)


name: RHOQ translocates to the Golgi-associated vesicle membranes (Schizosaccharomyces pombe)


name: (R)-3-hydroxybutanoate(in) + H(+)(in) => (R)-3-hydroxybutanoate(out) + H(+)(out)


name: 1-butyrylglycerol + H2O <=> butanoate + glycerol + H(+)


name: (13S,14R)-1,13-dihydroxy-N-methylcanadine + acetyl-CoA = (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + CoA


name: an inositol-1-phosphoceramide + GDP-alpha-D-mannose <=> a mannosylinositol-1-phospho-N-acyl-sphingoid base + GDP + H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + H(+) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O


name: 1-O-hexadecylglycerone 3-phosphate + H(+) + NADPH => 1-O-hexadecyl-sn-glycero-3-phosphate + NADP(+)


name: a quinone + an aldehyde + H2O => a carboxylate + a quinol + H(+)


name: phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Danio rerio)


name: RIPK1:RIPK3 oligomer binds MLKL (Bos taurus)


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: 2 H(+) + N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine => N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine


name: 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] (Homo sapiens)


name: METAP1/2 demethylates GNAT1 (Danio rerio)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Dictyostelium discoideum)


name: bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose = 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Dictyostelium discoideum)


name: Recruitment of PAK to the membrane by binding active RAC1 (Sus scrofa)


name: D-gluconate + NAD(+) <=> 5-dehydro-D-gluconate + H(+) + NADH


name: Interleukin-12 dissociates from Interleukin-12 receptor (Bos taurus)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Gallus gallus)


name: indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose => (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)


name: Active LTK receptor binds PI3K (Mus musculus)


name: Expression of SRY in testis differentiation (Homo sapiens)


name: Collagen type V degradation by MMP2,9,10 (Canis familiaris)


name: L-glutamine(in) + L-methionine(out) + Na(+)(out) <=> L-glutamine(out) + L-methionine(in) + Na(+)(in)


name: PDPK1 phosphorylates PKN1,2,3 (Xenopus tropicalis)


name: androsterone + H(+) + NADPH <=> 5alpha-androstane-3alpha,17beta-diol + NADP(+)


name: VAV3 is a GEF for Rho/Rac family kinases (Mus musculus)


name: 8 H(+) + heme b + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] => biliverdin IXalpha + CO + Fe(2+) + 3 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + rhazimal


name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate


name: PHF20 binds TP53 dimethylated on K370 and K382 (Homo sapiens)


name: 2'-deoxyguanosine + phosphate => dGMP + H2O


name: LPL hydrolyses TGs from mature CMs (Rattus norvegicus)


name: Exocytosis of specific granule lumen proteins (Schizosaccharomyces pombe)


name: Defective GGT1 does not hydrolyse GSH (Homo sapiens)


name: (S)-2-hydroxyglutarate + NAD(+) => 2-oxoglutarate + H(+) + NADH


name: steviolmonoside + UDP-alpha-D-glucose => rubusoside + UDP


name: PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Saccharomyces cerevisiae)


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Canis familiaris)


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Gallus gallus)


name: (S)-malate(out) + 2 H(+)(out) => (S)-malate(in) + 2 H(+)(in)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Caenorhabditis elegans)


name: FRAT proteins bind GSK3beta (Mus musculus)


name: Activated FGFR2 binds PLCG1 (Bos taurus)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Mus musculus)


name: SUMOylation of NPM1 with SUMO2,3 (Bos taurus)


name: (2Z,4E)-2-aminomuconate + H2O <=> (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH4(+)


name: SEMA6D binds to PLXNA1:TREM2:DAP12 (Rattus norvegicus)


name: Ca2+ influx into the post-synaptic cell (Rattus norvegicus)


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Mus musculus)


name: Formation of nonameric complex (Bos taurus)


name: (9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: GLB1 hydrolyzes SapB/C:LacCer (Dictyostelium discoideum)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Canis familiaris)


name: Ghrelin O-acyltransferase decanoylates Proghrelin (Bos taurus)


name: 4-aminobenzoate + all-trans-hexaprenyl diphosphate => 4-amino-3-all-trans-hexaprenylbenzoate + diphosphate


name: 3-hydroxy-1H-quinolin-4-one + O2 <=> CO + H(+) + N-formylanthranilate


name: 1-pyrroline-2-carboxylate + H(+) + NADPH => L-proline + NADP(+)


name: Ragulator binds Rag dimers (Danio rerio)


name: ADP-D-glycero-beta-D-manno-heptose + diphosphate => ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+)


name: CO2 + gibberellin A9 + H2O => gibberellin A24 + H(+) + O2


name: L-ribulose 5-phosphate => L-xylulose 5-phosphate


name: H2O + NAD(+) + phosphonoacetaldehyde => 2 H(+) + NADH + phosphonoacetate


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Danio rerio)


name: TP53BP1 recruits DCLRE1C to ATM (Homo sapiens)


name: p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 (Rattus norvegicus)


name: DAXX binds Ub-MDM2 and USP7 (Homo sapiens)


name: 4-methylpentan-2-one + hydrogen cyanide <=> (2S)-2-hydroxy-2,4-dimethylpentanenitrile


name: (2E,6E)-farnesyl diphosphate = (+)-alpha-santalene + diphosphate


name: N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: 2 H(+) + siroheme <=> 12,18-didecarboxysiroheme + 2 CO2


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Xenopus tropicalis)


name: DeHA hydrolyses to 2,3-DKG (Homo sapiens)


name: EP400 binds CDKN1A promoter (Canis familiaris)


name: Phosphorylation of GAB2 by SFKs (Canis familiaris)


name: (9Z)-octadecenoate + 12-hydroxyoctadecanoate + H(+) => 12-(9Z-octadecenoyloxy)-octadecanoate + H2O


name: 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + CO2 + CoA => (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + H(+) + malonyl-CoA


name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 (Gallus gallus)


name: AMY1-3 bind IAPP(34-70) (Xenopus tropicalis)


name: D-ribose 5-phosphate => alpha-D-ribose 1-phosphate


name: a ribonucleoside 5'-triphosphate + 2 H2O <=> a ribonucleoside 5'-phosphate + 2 H(+) + 2 phosphate


name: (3R)-3-isocyanylbutanoyl-AMP + diphosphate => (3R)-3-isocyanylbutanoate + ATP + H(+)


name: (2Z,6Z)-farnesyl diphosphate => (E)-alpha-bisabolene + diphosphate


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Bos taurus)


name: (4R)-hydroxyeicosasphinganine + hexacosanoyl-CoA => CoA + H(+) + N-hexacosanoyl-eicosan-(4R)-hydroxysphinganine


name: H2O + N-tetracosanoyl-taurine = taurine + tetracosanoate


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Rattus norvegicus)


name: ADP + D-ribose 5-phosphate + H(+) = ADP-D-ribose + phosphate


name: D-cellobiono-1,5-lactone + H2O <=> 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)


name: (2R)-3-phosphoglycerate + ADP-alpha-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+)


name: 7-methylxanthine + formaldehyde + H2O + NADP(+) => 1,7-dimethylxanthine + H(+) + NADPH + O2


name: RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA (Canis familiaris)


name: 4-hydroxybenzoate + chloride + H(+) => 4-chlorobenzoate + H2O


name: Translocation of active caspase-8 to the mitochondrial membrane (Sus scrofa)


name: Expression of STAT3-upregulated extracellular proteins (Homo sapiens)


name: TTR:RBP:atROL binds to STRA6 receptor (Bos taurus)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Xenopus tropicalis)


name: Interaction of other tyrosine kinases with p-KIT (Bos taurus)


name: diphosphate + GDP-beta-L-fucose => beta-L-fucose 1-phosphate + GTP + H(+)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Bos taurus)


name: L-lysyl-[lipoyl-carrier protein] + N(6)-octanoyl-L-lysyl-[glycine-cleavage complex H protein] <=> L-lysyl-[glycine-cleavage complex H protein] + N(6)-octanoyl-L-lysyl-[lipoyl-carrier protein]


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + L-lysyl(36)-[histone H3] + 2 succinate


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Mus musculus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Plasmodium falciparum)


name: 3-amino-5-hydroxybenzoate + ATP + holo-[aryl-carrier protein] => 3-amino-5-hydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate


name: glutaryl-CoA + L-lysyl-[protein] => CoA + H(+) + N(6)-glutaryl-L-lysyl-[protein]


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Gallus gallus)


name: Peroxynitrite oxidizes Peptide-Methionine residues (Homo sapiens)


name: a uridine in RNA + S-adenosyl-L-methionine <=> a 5-methyluridine in RNA + H(+) + S-adenosyl-L-homocysteine


name: D-alanine(in) + Na(+)(in) => D-alanine(out) + Na(+)(out)


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol <=> a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester


name: Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Homo sapiens)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate => 2-oxoglutarate + L-kynurenine


name: (1R,2R)-pseudoephedrine + NAD(+) = (R)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: SREBP1A,1C,2 translocates to the nucleus (Rattus norvegicus)


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Homo sapiens)


name: Formation of CDK4/6:CCND complexes (Rattus norvegicus)


name: citrate(out) + D-threo-isocitrate(in) = citrate(in) + D-threo-isocitrate(out)


name: TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains  (Canis familiaris)


name: N(alpha)-methyl-L-histidine + S-adenosyl-L-methionine <=> H(+) + N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-homocysteine


name: ELAC2 cleaves the 3' end of pre-tRNA (Homo sapiens)


name: G alpha (z) inhibits adenylate cyclase (Sus scrofa)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] <=> 1-[8-hydroxy-(9Z)-octadecenoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: phosphate + propanoyl-CoA = CoA + propanoyl phosphate


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Bos taurus)


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Bos taurus)


name: lipid transmembrane transporter activity


name: NCAM1 trans-homophilic interaction (Homo sapiens)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Plasmodium falciparum)


name: CX3 complex binds D-loop structures (Sus scrofa)


name: a 2-hydroxy carboxylate + O2 => a 2-oxocarboxylate + H2O2


name: CARM1 methylates arginine-18 (H3R17) of histone H3 (Mus musculus)


name: RHOG translocates to the ER membrane (Xenopus tropicalis)


name: aldehydo-D-glucose 6-phosphate + L-lysyl-[protein] = H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein]


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Bos taurus)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Rattus norvegicus)


name: 2-hydroxy-3-oxosuccinate + H(+) + NADH => NAD(+) + tartrate


name: acetoacetyl-CoA + acetyl-CoA + H2O => (3S)-hydroxy-3-methylglutaryl-CoA + CoA + H(+)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Schizosaccharomyces pombe)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Mus musculus)


name: Hikeshi binds HSP70s:ATP (Caenorhabditis elegans)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Gallus gallus)


name: The bound receptor dimerizes (Rattus norvegicus)


name: Relaxin receptor 1 binds relaxin 2 and 3 (Homo sapiens)


name: PTK6 binds ARHGAP35 (Caenorhabditis elegans)


name: IP6 transports from the cytosol to the nucleus (Homo sapiens)


name: 3-methoxy,4-hydroxy-5-all-trans-polyprenylbenzoate + H(+) + S-adenosyl-L-homocysteine => 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-methionine


name: DCC interaction with SIAH2 (Caenorhabditis elegans)


name: sIL27RA translocates from the cytoplasm to the extracellular region (Homo sapiens)


name: (4R)-4-hydroxy-2-oxoglutarate + L-glutamate => (4S)-4-hydroxy-L-glutamate + 2-oxoglutarate


name: SUMOylation of TOPORS with SUMO1 (Rattus norvegicus)


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Homo sapiens)


name: alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP => di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-2-acetyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: H(+) + L-arginine + NADPH + O2 => H2O + N(omega)-hydroxy-L-arginine + NADP(+)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Homo sapiens)


name: Thyrotropin is a heterodimer (Rattus norvegicus)


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Mus musculus)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Mus musculus)


name: TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)


name: GBF1 recruits ARF:GDP to the ERGIC (Rattus norvegicus)


name: CXADR binds to AMICA1 (Canis familiaris)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Gallus gallus)


name: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H2O <=> L-threonyl-[protein] + N-acetyl-D-glucosamine


name: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate => 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Dictyostelium discoideum)


name: H(+) + NADPH + 2 phytyl diphosphate => (14E,18E)-lycopadiene + 2 diphosphate + NADP(+)


name: 4-O-[(D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+) => 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol


name: (9Z,12Z)-octadecadienoate + O2 = (9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Sus scrofa)


name: G-protein coupled bile acid receptor binds lithocholic acid (Drosophila melanogaster)


name: Furin cleaves pro-protein Z to protein Z (Gallus gallus)


name: Trimerization of HSF1 in the nucleus (Schizosaccharomyces pombe)


name: (3R)-hydroxy-5-methylhexanoyl-[ACP] => (2E)-5-methylhexenoyl-[ACP] + H2O


name: WLS binds WNT ligands in the Golgi (Xenopus tropicalis)


name: Recruitment of ITK to SLP-76 (Canis familiaris)


name: 3 a menaquinol(in) + 2 H(+)(out) + nitrite(out) = 3 a menaquinone(in) + 2 H2O(out) + NH4(+)(out)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Gallus gallus)


name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) (Sus scrofa)


name: KIT binds ripretinib (Caenorhabditis elegans)


name: ATP + H2O + Na(+)(in) => ADP + H(+) + Na(+)(out) + phosphate


name: 2'-hydroxybiphenyl-2-sulfinate + H2O = biphenyl-2-ol + H(+) + sulfite


name: (2R)-3-phospho-glyceroyl phosphate + H(+) + NADPH => D-glyceraldehyde 3-phosphate + NADP(+) + phosphate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate


name: diphosphate + GDP-D-glucose => alpha-D-glucose 1-phosphate + GTP + H(+)


name: ATP + di-trans,octa-cis-undecaprenol <=> ADP + di-trans,octa-cis-undecaprenyl phosphate + H(+)


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Gallus gallus)


name: 2 (3R)-hydroxydecanoyl-[ACP] + H2O => (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + H(+) + 2 holo-[ACP]


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Xenopus tropicalis)


name: DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Rattus norvegicus)


name: D-xylose(out) + 2 Na(+)(out) <=> D-xylose(in) + 2 Na(+)(in)


name: Phosphorylation of IKK-beta by TAK1 (Homo sapiens)


name: dTTP + 2 H2O <=> dTMP + 2 H(+) + 2 phosphate


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-dodecanoyl-4'-phosphopantetheine => dodecanoyl-CoA + H2O


name: 26-hydroxyhexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] => 26-oxohexacosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(10Z,13Z,16Z)-docosatrienoyl-CoA + CO2 + CoA


name: TTLLs polyglutamylate tubulin (Mus musculus)


name: GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity


name: Interaction of particulate antigens with dendritic cell receptors (Rattus norvegicus)


name: FOLR2 transports FOLA from extracellular region to cytosol (Mus musculus)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Mus musculus)


name: 2-oxoglutarate + L-ectoine + O2 <=> 5-hydroxyectoine + CO2 + succinate


name: CoA + hexadecanal + NAD(+) => H(+) + hexadecanoyl-CoA + NADH


name: H2O + paraoxon = 4-nitrophenol + diethylphosphate + 2 H(+)


name: Loading of acetylcholine in synaptic vesicles (Rattus norvegicus)


name: catechol + O2 <=> cis,cis-muconate + 2 H(+)


name: Stimulation of IL8 transcription in senescent cells (Homo sapiens)


name: nuclear mineralocorticoid receptor binding


name: L-homocysteine + S-methyl-L-methionine = H(+) + 2 L-methionine


name: Active calmodulin binds CAMK2 (Mus musculus)


name: GDP-alpha-D-glucose + H2O = alpha-D-glucose 1-phosphate + GMP + 2 H(+)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Canis familiaris)


name: 9-hydroxy-octadecanoate + a 1,2-diacyl-sn-glycerol <=> 9-(acyloxy)-octadecanoate + a 1-acyl-sn-glycerol


name: RAN:GTP recruits nuclear envelope (NE) membranes (Caenorhabditis elegans)


name: acetyl-CoA + N-terminal L-methionyl-[tubulin] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]


name: "tubulin N-terminal N-acetyltransferase NAT9"


name: glycolaldehyde + H2O + NAD(+) = glycolate + 2 H(+) + NADH


name: Interaction of E3 with substrate and E2-Ub complex (Sus scrofa)


name: Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Rattus norvegicus)


name: (3R)-3-hydroxy-L-aspartate => glycine + glyoxylate


name: PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Sus scrofa)


name: a ganglioside GT1balpha + CMP-N-acetyl-beta-neuraminate = CMP + ganglioside GQ1b alpha + H(+)


name: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] => 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: eriodictyol-7-O-beta-D-glucoside + H2O = (S)-eriodictyol + beta-D-glucose


name: TDG excises 5-carboxylcytosine (Drosophila melanogaster)


name: Receptors CCR1, 2 and 8 bind CCL16 ligand (Gallus gallus)


name: Aggrecan binds Hyaluronan and HAPLN1 (Mus musculus)


name: (6S)-5,6,7,8-tetrahydrofolate + glycine + NAD(+) <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + CO2 + NADH + NH4(+)


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Canis familiaris)


name: RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Sus scrofa)


name: acetyl-CoA + O-(2-aminoethyl)-L-serine => CoA + H(+) + O-(2-acetamidoethyl)-L-serine


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Bos taurus)


name: 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H(+) + H2O <=> NH4(+) + pre-mycofactocin


name: CSF3R binds CSF3 dimer (Xenopus tropicalis)


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Bos taurus)


name: NOTCH1 coactivator complex binds the TBX6 gene (Homo sapiens)


name: 5,6,7,8-tetrahydropteridine + NAD(+) => 6,7-dihydropteridine + H(+) + NADH


name: H(+) + NADPH + O2 + tryprostatin B => demethoxyfumitremorgin C + 2 H2O + NADP(+)


name: ARRB mediates NOTCH1 ubiquitination (Homo sapiens)


name: MAPK1 phosphorylates SOX10 (Schizosaccharomyces pombe)


name: N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Saccharomyces cerevisiae)


name: CDH11 associates with catenins (Homo sapiens)


name: 9,10-epoxy-(12Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-9,10-epoxy-(12Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glucose-6-phosphate dehydrogenase (coenzyme F420) activity


name: C5a anaphylatoxin chemotactic receptor binding


name: Initial activation of proMMP2 by MMP14 (Homo sapiens)


name: ALK binds ligand pleiotrophin (PTN) (Sus scrofa)


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA => (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H2O


name: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) <=> 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH


name: L-lysyl-[protein] + octanoyl-[ACP] <=> H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]


name: NNT dimer transfers proton from NADPH to NAD+ (Rattus norvegicus)


name: SEC24A,B:SEC23A bind SEC22B (Rattus norvegicus)


name: VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: (R)-carnitine + octadecanoyl-CoA => CoA + O-octadecanoyl-(R)-carnitine


name: griseophenone B + H(+) + O2 + reduced [NADPH--hemoprotein reductase] = desmethyl-dehydrogriseofulvin + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (3R)-3-isocyanylbutanoate + 3 CO2 + 2 H2O + 2 succinate => (3R)-3-[(carboxymethyl)amino]butanoate + 2 2-oxoglutarate + 2 O2


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Sus scrofa)


name: EPH:EFN tetramers oligomerise (Canis familiaris)


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Rattus norvegicus)


name: 3beta-hydroxyandrost-5-en-17-one + H(+) + NADPH => androst-5-en-3beta,17beta-diol + NADP(+)


name: 2 Na(+)(in) + tauronorcholate(in) => 2 Na(+)(out) + tauronorcholate(out)


name: H2O + N(4)-acetyl-2'-deoxycytidine => 2'-deoxycytidine + acetate + H(+)


name: (Z)-gamma-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: MECP2 binds MEF2C gene promoter (Homo sapiens)


name: Detection of damage during initiation of DNA synthesis in S-phase (Canis familiaris)


name: RHOD:GTP recruits DAIPH2-3 to endosomes (Sus scrofa)


name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Bos taurus)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose <=> 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: abacavir [extracellular] => abacavir [cytosol] (Mus musculus)


name: Basigin binds Matrix metalloproteinase-1 (Homo sapiens)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Schizosaccharomyces pombe)


name: D-glucarate + 2 H(+) + NADH => D-glucuronate + H2O + NAD(+)


name: Cannabinoid receptors can bind cannabinoids (Canis familiaris)


name: Synthesis of antigenomic RNA of human respiratory syncytial virus (Homo sapiens)


name: FASL binds FAS Receptor (Xenopus tropicalis)


name: a ganglioside GM2 + UDP-alpha-D-galactose <=> a ganglioside GM1 + H(+) + UDP


name: glucagon-like peptide 1 receptor activity


name: Activated MET recruits GRB2-1:SOS1 (Caenorhabditis elegans)


name: Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm (Danio rerio)


name: IDH2 dimer decarboxylates isocitrate (Danio rerio)


name: TAT aminates HPP (Dictyostelium discoideum)


name: apelin-16 + L-phenylalanine => apelin-17 + H2O


name: (S)-beta-macrocarpene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO2 + NADPH


name: L-xylono-1,4-lactone + O2 <=> dehydro-L-arabinono-1,4-lactone + H(+) + H2O2


name: SUMO-p-N protein dimer binds genomic RNA (Homo sapiens)


name: KDM5A-D demethylate Me3K5-histone H3 (Saccharomyces cerevisiae)


name: HMGCR dimer binds statins (Schizosaccharomyces pombe)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Bos taurus)


name: CYP24A1 24-hydroxylates CTL (Danio rerio)


name: ATP + coproporphyrinogen III(in) + H2O <=> ADP + coproporphyrinogen III(out) + H(+) + phosphate


name: Cleavage of mRNA at the 3'-end (Canis familiaris)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Rattus norvegicus)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Mus musculus)


name: (2E)-geranyl diphosphate + H2O = (R)-linalool + diphosphate


name: all-trans-13,14-dihydroretinal + H(+) + NADH => all-trans-13,14-dihydroretinol + NAD(+)


name: PLK2, MAPK14 phosphorylate ADAM17 (Homo sapiens)


name: 3-oxooctacosanyol-CoA + CO2 + CoA => H(+) + hexacosanoyl-CoA + malonyl-CoA


name: a ribonucleoside 5'-diphosphate + ATP <=> a ribonucleoside 5'-triphosphate + ADP


name: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 <=> 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)


name: (3R)-[(10S)-11-epoxyfarnesyl]-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate + H(+) <=> asnovolin H


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: (2E)-butenoyl-CoA + H2O => 4-hydroxybutanoyl-CoA


name: H2O + L-tryptophanamide <=> L-tryptophan + NH4(+)


name: (E)-5-hydroxyferulate + S-adenosyl-L-methionine <=> (E)-sinapate + H(+) + S-adenosyl-L-homocysteine


name: Activated FGFR4:p-FRS binds GRB2:SOS1 (Bos taurus)


name: Formation of CSL-NICD coactivator complex (Mus musculus)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Caenorhabditis elegans)


name: H(+) + H2 + oxidized coenzyme F420-(gamma-L-Glu)(n) => reduced coenzyme F420-(gamma-L-Glu)(n)


name: JAK3 binds JAK3 inhibitors (Mus musculus)


name: Loss of C-Nap-1 from centrosomes (Canis familiaris)


name: RHOF GAPs stimulate RHOF GTPase activity (Bos taurus)


name: transcription antitermination factor activity, RNA binding


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Bos taurus)


name: ATP + H2O + phosphate(out) => ADP + H(+) + 2 phosphate(in)


name: SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Caenorhabditis elegans)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated IKK phosphorylates I-kappaB (Canis familiaris)


name: HEXB cleaves the terminal GalNAc from DS (Dictyostelium discoideum)


name: (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) = catechol + CO2 + NADH


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Canis familiaris)


name: Receptor CCR6 binds CCL20 ligand (Rattus norvegicus)


name: all-trans-retinol + NADP(+) = all-trans-retinal + H(+) + NADPH


name: chlorophyllide a + 2 H(+) = Mg(2+) + pheophorbide a


name: p-STAT5 dissociates from the receptor complex (Sus scrofa)


name: ATP + H(+) + NADPH + piperonylate <=> AMP + diphosphate + NADP(+) + piperonal


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 => (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate


name: ADP + L-serine => AMP + H(+) + O-phospho-L-serine


name: APC/C:Cdh1-mediated degradation of Skp2 (Canis familiaris)


name: Recruitment of TRAF3 to MAVS (Homo sapiens)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Sus scrofa)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + dodecanoyl-[ACP] = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + holo-[ACP]


name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Bos taurus)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Saccharomyces cerevisiae)


name: D-arabinitol + NADP(+) => D-xylulose + H(+) + NADPH


name: 3-hydroxyglutarate(out) + 3 Na(+)(out) = 3-hydroxyglutarate(in) + 3 Na(+)(in)


name: chloride + H(+) + hydroxyatrazine => atrazine + H2O


name: Mis18 complex binds the centromere (Homo sapiens)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Mus musculus)


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Xenopus tropicalis)


name: HTR1A binds HTR1A agonists (Caenorhabditis elegans)


name: SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Homo sapiens)


name: H2O + tridodecanoylglycerol <=> 2,3-didodecanoyl-sn-glycerol + dodecanoate + H(+)


name: Nef mediated activation of the T-cell receptor (Homo sapiens)


name: AGK:Mg2+ phosphorylates MAG, DAG (Dictyostelium discoideum)


name: dihydroprecondylocarpine acetate + NADPH => (+)-vincadifformine + acetate + NADP(+)


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Sus scrofa)


name: USP33 deubiquitinates ROBO1 (Bos taurus)


name: dopamine + hexadecanoyl-CoA = CoA + H(+) + N-hexadecanoyl-dopamine


name: 2-hydroxyhexadecanoyl-CoA + sphinganine = CoA + H(+) + N-(2-hydroxyhexadecanoyl)-sphinganine


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: IL20 binds IL20RA:JAK1:IL20RB (Homo sapiens)


name: a quinone + shikimate = 3-dehydroshikimate + a quinol


name: CBL ubiquitinates PI3K (Canis familiaris)


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Homo sapiens)


name: 1-(9Z-octadecenoyl)-2-O-(5Z,8Z,11Z,14Z-eicosatetraenyl)-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-O-(5Z,8Z,11Z,14Z)-eicosatetraenylglycerol + H(+)


name: H2O + octanedioyl-CoA = CoA + H(+) + octanedioate


name: atrochrysone + CO2 => atrochrysone carboxylate + H(+)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Rattus norvegicus)


name: PSIP1 binds MEN1 associated with MLL2 complex (Sus scrofa)


name: ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA (Dictyostelium discoideum)


name: H(+) + hexanal + NADPH => hexan-1-ol + NADP(+)


name: Elastin cross-linking by lysyl oxidase (Homo sapiens)


name: Cytosolic PLK1 translocates to the nucleus (Danio rerio)


name: dihydrochanoclavine-I aldehyde => 6,8-dimethyl-6,7-didehydroergoline + H2O


name: ROS oxidize thioredoxin and activate MAP3K5 (Rattus norvegicus)


name: H2O + L-asparagine + O2 <=> 2-oxosuccinamate + H2O2 + NH4(+)


name: RAC1 and CDC42 activate PAK3 (Homo sapiens)


name: 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: SRC phosphorylates RUNX3 (Caenorhabditis elegans)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Mus musculus)


name: CYSLT2 binds LTC4,LTD4,LTE4 (Mus musculus)


name: a (2S,3R)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Schizosaccharomyces pombe)


name: menaquinol-8 + oxaloacetate => (S)-malate + menaquinone-8


name: H2O + ML-236C carboxylate => 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate


name: abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP (Homo sapiens)


name: ADCY3:GNAL:GTP converts ATP to cAMP (Homo sapiens)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] => 6beta-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Caenorhabditis elegans)


name: (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase] => acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: L-proline + NAD(+) <=> 1-pyrroline-5-carboxylate + 2 H(+) + NADH


name: PI3K synthesizes PIP3 downstream of ALK (Gallus gallus)


name: Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Gallus gallus)


name: p-4Y-PLCG1 dissociates from activated FGFR1 (Sus scrofa)


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Caenorhabditis elegans)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Saccharomyces cerevisiae)


name: Parathyroid hormone receptor can bind parathyroid hormone (Canis familiaris)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Sus scrofa)


name: terpentedienyl diphosphate => diphosphate + terpentetriene


name: argininosuccinate <=> fumarate + arginine (Sus scrofa)


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Xenopus tropicalis)


name: glyoxal + L-lysyl-[protein] <=> N(6)-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein]


name: an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH


name: 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP <=> 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+) => 3-chlorocatechol + H(+) + NADH


name: (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: Activation of Rap1 by membrane-associated GEFs (Canis familiaris)


name: D-maltobionate + H(+) => D-maltobiono-1,5-lactone + H2O


name: Association of procollagen type VIII (Mus musculus)


name: 3-hydroxy-L-aspartyl-[protein] + CO2 + succinate => 2-oxoglutarate + L-aspartyl-[protein] + O2


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Xenopus tropicalis)


name: N,N-dihydroxy-L-aspartate = (2S)-2-nitrosobutanedioate + H2O


name: Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Sus scrofa)


name: [DsrC protein]-dithiol + 2 a quinone + 2 H(+) + hydrogen sulfide = [DsrC protein]-trisulfide + 2 a quinol + H(+)


name: solute:inorganic anion antiporter activity


name: HMGB1 binds LTP (Saccharomyces cerevisiae)


name: Aggrecan binds Hyaluronan and HAPLN1 (Homo sapiens)


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Saccharomyces cerevisiae)


name: 9,12-cis-hexadecadienoic acid delta 15 desaturase activity


name: (+)-artemisinic alcohol + O2 + reduced [NADPH--hemoprotein reductase] <=> (+)-artemisinic aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Self-ubiquitination of RNF41 (Bos taurus)


name: KIT binds ripretinib (Rattus norvegicus)


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Canis familiaris)


name: L-cysteinyl-[protein] + tetradecanoyl-CoA => CoA + S-tetradecanoyl-L-cysteinyl-[protein]


name: CO2 + UDP-alpha-D-xylose => H(+) + UDP-alpha-D-glucuronate


name: 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O <=> 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + phosphate


name: HSBP1 oligomer binds ESRs (Rattus norvegicus)


name: SRD5A3 dehydrogenates TEST to DHTEST (Homo sapiens)


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Canis familiaris)


name: Dopa is oxidized to dopaquinone by TYR (Caenorhabditis elegans)


name: Activated thrombin (factor IIa) cleaves PAR3,4, activating them (Sus scrofa)


name: 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetyl-CoA


name: beta-D-glucosyl-N-octanoylsphing-4E-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octanoylsphing-4-enine


name: acetyl-CoA + hexadecanoyl-CoA <=> 3-oxooctadecanoyl-CoA + CoA


name: H(+) + NADPH + vanillin = 4-hydroxy-3-methoxy-benzenemethanol + NADP(+)


name: Phosphorylation of complexed TSC2 by PKB (Sus scrofa)


name: 2 Na(+)(out) + pregnenolone sulfate(out) = 2 Na(+)(in) + pregnenolone sulfate(in)


name: kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin (Canis familiaris)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Plasmodium falciparum)


name: H(+) + heptan-2-one + NADPH + O2 <=> H2O + NADP(+) + pentyl acetate


name: p-S MAPK6 phosphorylates NCOA3 (Homo sapiens)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Canis familiaris)


name: H2O + L-histidinal + NAD(+) = 2 H(+) + L-histidine + NADH


name: 2-all-trans-decaprenylphenol + H(+) + NADPH + O2 => 3-(all-trans-decaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: 2 berberine + 2 H2O => 2 columbamine + O2


name: ATP + L-threonyl-[rhodopsin] <=> ADP + H(+) + O-phospho-L-threonyl-[rhodopsin]


name: TBK1 is phosphorylated within the activated TLR4 complex (Bos taurus)


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Caenorhabditis elegans)


name: verbascose galactinol:ajugose galactosyltransferase activity


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Homo sapiens)


name: (E)-cinnamate + H(+) + NADPH + O2 = H2O + NADP(+) + trans-2-coumarate


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a (9Z)-octadecenoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: chloride + chlorohydroquinone + glutathione disulfide + H(+) => 2,5-dichlorohydroquinone + 2 glutathione


name: Binding of CBL to EGFR (Drosophila melanogaster)


name: GPRC6A can bind L-alpha amino acids and calcium (Danio rerio)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Schizosaccharomyces pombe)


name: TP53INP1 and HIPK2 bind TP53 (Mus musculus)


name: TXLNA (IL14) binds syntaxin1A (Caenorhabditis elegans)


name: "4,6-alpha-glucanotransferase (linear and branched substrates, branched products)"


name: a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2 = a 1-acyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)


name: (2E,6E)-farnesyl diphosphate => (1S,8aR)-delta-cadinene + diphosphate


name: NACT co-transports trivalent citrate and a sodium ion (Homo sapiens)


name: 7-deoxyloganate + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + loganate + oxidized [NADPH--hemoprotein reductase]


name: Cholecystokinin receptors bind cholecystokinin (Canis familiaris)


name: adenine + alpha-D-ribose 1-phosphate => adenosine + phosphate


name: 2 ATP + 2 H2O + 2 L-glutamine + Ni-sirohydrochlorin = 2 ADP + 2 H(+) + 2 L-glutamate + Ni-sirohydrochlorin a,c-diamide + 2 phosphate


name: p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Rattus norvegicus)


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Xenopus tropicalis)


name: 2 L-ascorbate + N-(9Z,12Z,15Z)-octadecatrienoylglycine + O2 <=> H2O + 2 monodehydro-L-ascorbate radical + N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Xenopus tropicalis)


name: (+)-exo-beta-bergamotene + 3 O2 + 2 reduced [NADPH--hemoprotein reductase] => 5-dehydro-6-demethoxyfumagillol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Dimerization of p-S446-IRF5 (Bos taurus)


name: ITGA4:ITGB1 binds natalizumab (Gallus gallus)


name: 2 NADPH + palmatine + S-adenosyl-L-methionine => corydaline + 2 NADP(+) + S-adenosyl-L-homocysteine


name: QPRT transfers PRIB to QUIN to form NAMN (Sus scrofa)


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Sus scrofa)


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Canis familiaris)


name: H(+) + NADPH + O2 + sitosterol <=> 2 H2O + NADP(+) + stigmasterol


name: Caspase 3-mediated cleavage of PKC delta (Gallus gallus)


name: CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 (Xenopus tropicalis)


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Rattus norvegicus)


name: Inactivation of LCK by PTPN22 (Mus musculus)


name: Association of  PARVA with TESK1 (Danio rerio)


name: (2Z,6E)-farnesyl diphosphate => beta-bisabolene + diphosphate


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Canis familiaris)


name: Two DITs combine to form thyroxine (Caenorhabditis elegans)


name: LDL + LDLR => LDL:LDLR complex (Canis familiaris)


name: p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP (Homo sapiens)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Caenorhabditis elegans)


name: glutarate + 2 H(+) + NADPH => 5-oxopentanoate + H2O + NADP(+)


name: 9alpha-copalyl diphosphate + H2O = diphosphate + syn-copalol


name: (12E)-labda-8(17),12,14-triene + diphosphate => (+)-copalyl diphosphate


name: Phosphorylation of LAT by p-SYK (Rattus norvegicus)


name: a ribonucleoside + phosphate => a ribonucleoside 3'-phosphate + H2O


name: The phagophore extends from the PIP3-enriched structure (Schizosaccharomyces pombe)


name: diphosphate + dTDP-D-galactose => alpha-D-galactose 1-phosphate + dTTP + H(+)


name: Beta-catenin recruits CDC73 and LEO1 (Drosophila melanogaster)


name: TFAP2B homodimer binds YEATS4 (Canis familiaris)


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Drosophila melanogaster)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Sus scrofa)


name: Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) (Rattus norvegicus)


name: L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: (R)-2-hydroxypropyl-coenzyme M <=> (R)-1,2-epoxypropane + coenzyme M


name: D-glucaro-1,4-lactone = 5-dehydro-4-deoxy-D-glucarate + H(+)


name: GIP receptor binds gastric inhibitory peptide (Canis familiaris)


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Mus musculus)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] => 6alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII (Sus scrofa)


name: (2S)-2-hydroxy-2-(3-methoxyphenyl)acetonitrile => 3-methoxybenzaldehyde + hydrogen cyanide


name: Recruitment of SYK to phosphorylated ITAMs (Homo sapiens)


name: FUOM isomerises alpha-Fuc to beta-Fuc (Rattus norvegicus)


name: EPPIN protein complex binds bacteria (Bos taurus)


name: HRSP12 deaminates 2AA to 2OBUTA (Xenopus tropicalis)


name: GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O <=> (11R,12R)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Rattus norvegicus)


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a fatty acid + H(+)


name: ABCA4 mediates atRAL transport (Caenorhabditis elegans)


name: SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Sus scrofa)


name: S-adenosyl-L-methionine + zymosterol <=> fecosterol + H(+) + S-adenosyl-L-homocysteine


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) => (4Z)-2-oxohept-4-enedioate + CO2


name: CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Bos taurus)


name: L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Caenorhabditis elegans)


name: CYP26C1 4-hydroxylates 9cRA (Homo sapiens)


name: Crk binds to the active PDGF receptor (Caenorhabditis elegans)


name: 3-methyl-3-sulfanylhexan-1-ol + NH4(+) + pyruvate => H2O + S-(1-hydroxy-3-methylhexan-3-yl)-L-cysteine


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Sus scrofa)


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Rattus norvegicus)


name: Formation of dehydro-lysinonorleucine cross-links (Bos taurus)


name: 4-acetoxybenzaldehyde + H(+) + NADH => 4-acetoxybenzyl alcohol + NAD(+)


name: glycine(in) + L-phenylalanine(out) <=> glycine(out) + L-phenylalanine(in)


name: lactose(out) + N(pros)-phospho-L-histidyl-[protein] = L-histidyl-[protein] + lactose 6-phosphate(in)


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Canis familiaris)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Mus musculus)


name: an L-alpha-amino acid + ATP + holo-[ACP] = AMP + an L-alpha-aminoacyl-[ACP] + diphosphate


name: 2-oxoglutarate(out) + glutarate(in) <=> 2-oxoglutarate(in) + glutarate(out)


name: 2-oxobutanoate + L-alanine <=> (2S)-2-aminobutanoate + pyruvate


name: eicosanoyl-CoA + glycine => CoA + H(+) + N-eicosanoylglycinate


name: 5,10-methylenetetrahydrosulfopterin + glycine + H2O => L-serine + tetrahydrosulfopterin


name: phosphorylated perilipin + H2O -> perilipin + orthophosphate (Homo sapiens)


name: 3,4-dihydroxybenzoyl-5'-AMP + diphosphate => 3,4-dihydroxybenzoate + ATP + H(+)


name: (R)-4'-phosphopantothenate + ATP + L-cysteine => AMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine


name: 5-aminopentanal + H2O + NAD(+) => 5-aminopentanoate + 2 H(+) + NADH


name: Caspase-mediated cleavage of Lamin A (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + beta-D-galactosyl-(1<->1)-sphing-4-enine => 6-O-sulfo-beta-D-galactosyl-(1<->1)-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)


name: Abortive initiation after formation of the first phosphodiester bond (Rattus norvegicus)


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Mus musculus)


name: Exocytosis of ficolin-rich granule lumen proteins (Drosophila melanogaster)


name: PLC beta-mediated PIP2 hydrolysis (Mus musculus)


name: (1R,4R)-bornane-2,5-dione + FMNH2 + O2 => (1R,4R)-5-oxo-1,2-campholide + FMN + H(+) + H2O


name: PTK6 phosphorylates KHDRBS2 (Bos taurus)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Caenorhabditis elegans)


name: PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Mus musculus)


name: (E)-feruloyl-CoA + H2O => 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA


name: Complement factor I binds to MCP, CR1:C4b, C3b (Homo sapiens)


name: (S)-8-oxocitronellyl enol <=> cis-cis-nepetalactol


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Danio rerio)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Drosophila melanogaster)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Sus scrofa)


name: L-methionine(in) + S-methylmercury-L-cysteine(out) => L-methionine(out) + S-methylmercury-L-cysteine(in)


name: 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxylate + H(+) + holo-[ACP] => 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Mus musculus)


name: NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)


name: 6-hydroxyhexan-6-olide = 6-oxohexanoate + H(+)


name: (E)-hexadec-2-enoate + 2 H(+) + NADH => (2E)-hexadecenal + H2O + NAD(+)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Caenorhabditis elegans)


name: 1-acyl-2-(9-cyclopronane)-acyl-sn-glycero-3-phospholipid + H(+) + S-adenosyl-L-homocysteine => 1-acyl-2-(9Z)-enoyl-sn-glycero-3-phospholipid + S-adenosyl-L-methionine


name: 24,25-dihydrolanosterol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Homo sapiens)


name: 3-dehydrocarnitine + acetyl-CoA = 3-dehydrocarnityl-CoA + acetate


name: NAD(+) + resolvin D2 = 7-oxoresolvin D2 + H(+) + NADH


name: (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] => phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit]


name: SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ (Drosophila melanogaster)


name: (2-aminoethyl)phosphonate + CTP = CMP-(2-aminoethyl)phosphonate + diphosphate


name: L-arginine(out) + L-glutamine(in) + Na(+)(in) => L-arginine(in) + L-glutamine(out) + Na(+)(out)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine <=> 4-O-([2-N-acetyl-alpha-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate


name: (beta-L-Ara4N)2-(Kdo)2-lipid A + 2 di-trans,octa-cis-undecaprenyl phosphate => 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Schizosaccharomyces pombe)


name: hexanoate + sphing-4-enine => H2O + N-(hexanoyl)sphing-4-enine


name: O2 + reduced [NADPH--hemoprotein reductase] + solavetivol = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + solavetivone


name: Collagen type VII dimerization (Rattus norvegicus)


name: G protein-coupled serotonin receptor activity


name: Activated FGFR4 binds PLCG1 (Homo sapiens)


name: a (3R)-3-isocyanyl-fatty acid + ATP + holo-[ACP] <=> a (3R)-3-isocyanyl-fatty acyl-[ACP] + AMP + diphosphate


name: NPPA(124-151) binds NPR1 (Xenopus tropicalis)


name: NTRK3(496-641) binds NELFB (Homo sapiens)


name: (E)-4-coumaroyl-CoA + H(+) + NADPH => (E)-4-coumaraldehyde + CoA + NADP(+)


name: RHOD translocates to the Golgi membrane (Drosophila melanogaster)


name: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein]


name: CoA + O-decanoyl-L-seryl-[protein] => decanoyl-CoA + L-seryl-[protein]


name: SDH complex dehydrogenates succinate (Schizosaccharomyces pombe)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Sus scrofa)


name: (3R)-3-hydroxybutanoyl-CoA + NADP(+) => acetoacetyl-CoA + H(+) + NADPH


name: malonate(out) + phosphate(in) <=> malonate(in) + phosphate(out)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Bos taurus)


name: CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Mus musculus)


name: Duplex miRNA is loaded into Argonaute (Gallus gallus)


name: 2-hexadecanoylglycerol + H2O => glycerol + H(+) + hexadecanoate


name: Association of profilin with monomeric actin (Danio rerio)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Sus scrofa)


name: Glycosylation of Hh (Xenopus tropicalis)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Canis familiaris)


name: 20 H(+) + holo-[compactin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH <=> 9 CO2 + 9 CoA + dihydro-ML-236C-[compactin nonaketide synthase] + 6 H2O + 11 NADP(+)


name: RRAGA,B hydrolyzes GTP (Drosophila melanogaster)


name: H(+) + NADH + orotate => (S)-dihydroorotate + NAD(+)


name: Endocytosis of TRAM (TICAM2) (Canis familiaris)


name: PGE2 is dehydrated to PGA2 (Homo sapiens)


name: H(+) + L-xylonate => H2O + L-xylono-1,4-lactone


name: COP9 and TOR1 deneddylate STON2 (Sus scrofa)


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Caenorhabditis elegans)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Homo sapiens)


name: ATP + biotin + L-lysyl-[protein] => AMP + diphosphate + H(+) + N(6)-biotinyl-L-lysyl-[protein]


name: 3,4-dihydroxyphenylacetate + H(+) = 4-methylcatechol + CO2


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Bos taurus)


name: Activated FGFR3 phosphorylates FRS2 (Gallus gallus)


name: Cleavage of hypoxanthine by MPG glycosylase (Xenopus tropicalis)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Schizosaccharomyces pombe)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Xenopus tropicalis)


name: 2 H(+) + H2O + N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] => N-(8'-oxogeranyl)-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase]


name: CO2 + dATP + H2O => ATP + formate + H(+)


name: H(+) + sulfate + sungeidine A => sulfosungeidine F


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Canis familiaris)


name: 5beta-androstane-3,17-dione + NADP(+) => androst-4-ene-3,17-dione + H(+) + NADPH


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate <=> (Z)-beta-farnesene + diphosphate


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Xenopus tropicalis)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Canis familiaris)


name: D-xylose(in) + 2 Na(+)(in) => D-xylose(out) + 2 Na(+)(out)


name: Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Drosophila melanogaster)


name: 25-hydroxy 3-oxocholestane + AH2 => 3-oxocholestane + A + H2O


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Mus musculus)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Homo sapiens)


name: ATP-dependent polynucleotide 5'-hydroxyl-kinase activity


name: Glycosylated M localizes to the Golgi membrane (Homo sapiens)


name: SUMOylation of ING2 with SUMO1 (Mus musculus)


name: Ubiquitinated DVL is degraded by the proteasome (Sus scrofa)


name: Autophosphorylation of LYN kinase (Canis familiaris)


name: PRODH oxidises L-Pro to 1PYR-5COOH (Rattus norvegicus)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DHTKD1 dimer decarboxylates 2-OA (Drosophila melanogaster)


name: Group 3 - Selective Cl- transport (Dictyostelium discoideum)


name: 2-acyl LPI is acylated to PI by MBOAT7 (Saccharomyces cerevisiae)


name: UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out) = UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + H(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + xanthotoxin <=> 5-hydroxyxanthotoxin + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-4-hydroxymandelate + O2 <=> 4-hydroxyphenylglyoxylate + H2O2


name: RFC binding displaces Pol Alpha (Canis familiaris)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Canis familiaris)


name: acetolactate synthase regulator activity


name: (R,R)-chrysanthemyl diphosphate + H2O => (R,R)-chrysanthemol + diphosphate


name: collagen binding involved in cell-matrix adhesion


name: SUMOylation of PML with SUMO3 (Dictyostelium discoideum)


name: HOXA3 chromatin is activated (Homo sapiens)


name: Activation of RAC1 by VAV (Mus musculus)


name: ganoderate Jc + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => ganoderate TR + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-deoxy-D-xylulose + ATP = 1-deoxy-D-xylulose 5-phosphate + ADP + H(+)


name: 3,4-dihydroxybenzaldehyde + AH2 + tyramine => A + H2O + norbelladine


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Sus scrofa)


name: CHST14 transfers SO4(2-) to GalNAc in dermatan or DS (Xenopus tropicalis)


name: SLC5A6 transports vitamins from extracellular region to cytosol (Rattus norvegicus)


name: 1-hexadecanoylglycerol + H2O <=> glycerol + H(+) + hexadecanoate


name: Activation of RAS by p-KIT bound SOS1 (Homo sapiens)


name: O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2


name: (7S)-O-acetylsalutaridinol = acetate + H(+) + thebaine


name: TRiC/CCT binds unfolded G-protein beta subunit (Sus scrofa)


name: PTEN undergoes monoubiquitination (Schizosaccharomyces pombe)


name: Alternative endo-mannosidase I route (Homo sapiens)


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Xenopus tropicalis)


name: 2-oxoglutarate(out) + 3 Na(+)(out) => 2-oxoglutarate(in) + 3 Na(+)(in)


name: 1,2-dihydro-alpha-santonin + NADP(+) <=> alpha-santonin + H(+) + NADPH


name: (S)-2-methylbutanoate + compactin diol lactone + H(+) => H2O + mevastatin


name: a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Homo sapiens)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Bos taurus)


name: beta-D-glucose + kaempferol => H2O + kaempferol 3-O-beta-D-glucoside


name: a 4-H-anthocyanidin with a 3-hydroxy group + H2O => a (4S)-2,3-dehydroflavan-3,4-diol + H(+)


name: (PTN,MDK):PTPRZ oligomerizes (Homo sapiens)


name: p-2S-SMAD2,3:SMAD4:SP1 binds CDKN2B gene promoter (Homo sapiens)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Caenorhabditis elegans)


name: NEDD4L ubiquitin ligase binds SMAD7 (Homo sapiens)


name: H2O + sphinga-4E,14Z-dienine-1-phosphate <=> phosphate + sphinga-4E,14Z-dienine


name: PINK1 phosphorylates PRKN at S65 (Bos taurus)


name: FYN phosphorylates PAK2 (Caenorhabditis elegans)


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Sus scrofa)


name: Interaction of PAK1 with Rac1-GTP (Sus scrofa)


name: 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O <=> ADP-D-ribose + H(+) + L-glutamyl-[protein]


name: ALOXE3 isomerises 12R-HpETE to HXA3 (Bos taurus)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + NAD(+) = androst-4-ene-3,11,17-trione + H(+) + NADH


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Mus musculus)


name: (S)-2-methyl-3-oxopropanoate + H2O + NAD(+) = 2 H(+) + methylmalonate + NADH


name: H2O + L-tryptophan + NAD(+) = H(+) + indole-3-pyruvate + NADH + NH4(+)


name: D-glucono-1,5-lactone + H2O2 => beta-D-glucose + O2


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Gallus gallus)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Rattus norvegicus)


name: NADPH + 2 O2 <=> H(+) + NADP(+) + 2 superoxide


name: JAK1 binds IL4R in IL13-bound IL13R type II (Bos taurus)


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Bos taurus)


name: WDR5 binds Me2sR3-replicative histone H3 (Dictyostelium discoideum)


name: RHOF GAPs stimulate RHOF GTPase activity (Danio rerio)


name: MET phosphorylates CBL (Caenorhabditis elegans)


name: H2O + N-terminal L-tryptophanyl-L-alpha-aminoacyl-[peptide] => L-tryptophan + N-terminal L-alpha-aminoacyl-[peptide]


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Bos taurus)


name: DHODH:FMN oxidises (S)-DHO to orotate (Canis familiaris)


name: IC-asc-C7-CoA + O2 <=> H2O2 + IC-asc-DeltaC7-CoA


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Drosophila melanogaster)


name: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose => alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: ADRM1:26S proteaseome binds USP14 (Rattus norvegicus)


name: Ubiquitinated Orc1 enters the cytosol (Schizosaccharomyces pombe)


name: PIAS3 SUMOylates PGR with SUMO1 (Gallus gallus)


name: NMT1/2 transfer MYS to GNAT1 (Sus scrofa)


name: (R)-glycerate + D-glucose => (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + H2O


name: 2-oxoglutarate + a 1,N(6)-etheno-2'-deoxyadenosine in double-stranded DNA + H2O + O2 => a 2'-deoxyadenosine in double-stranded DNA + CO2 + glyoxal + succinate


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Bos taurus)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Sus scrofa)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Caenorhabditis elegans)


name: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphate => a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: p-T,Y MAPK dimers translocate to nucleus (Bos taurus)


name: (22S)-22-hydroxycampest-4-en-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (22S)-22-hydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate


name: CMP-N-acetyl-beta-neuraminate + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide <=> CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide


name: (2E,6E,10E,14E)-geranylfarnesol + H2O => (17E)-cheilanthenediol


name: a (2R)-2-hydroperoxy fatty acid + H(+) <=> a fatty aldehyde + CO2 + H2O


name: 2-oxoglutarate + L-histidyl-[ribosomal protein uL15] + O2 = (3S)-3-hydroxy-L-histidyl-[ribosomal protein uL15] + CO2 + succinate


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Homo sapiens)


name: Defective TRAF3 does not transmit the signal (Homo sapiens)


name: H(+) + NADPH + prostaglandin E1 = NADP(+) + prostaglandin F1


name: POLK incorporates dNMP opposite to damaged DNA base (Caenorhabditis elegans)


name: BCDIN3D dimethylates 5' phosphate of pre-miR-145 (Homo sapiens)


name: Release of noradrenaline  at the synapse (Caenorhabditis elegans)


name: AVPR1A,2 bind AVPR antagonists (Danio rerio)


name: A + dodecanedioyl-CoA => (2E)-dodecenedioyl-CoA + AH2


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene + A <=> 1,1'-dihydroxy-3,4-didehydro-1,2-dihydrolycopene + AH2


name: H(+) + N(1)-methylpseudouridine(54) in tRNA + S-adenosyl-L-homocysteine => pseudouridine(54) in tRNA + S-adenosyl-L-methionine


name: D-galacto-hexodialdose + H2O2 => D-galactose + O2


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Canis familiaris)


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Canis familiaris)


name: angiotensin-(1-9) + L-leucine => angiotensin I + H2O


name: SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Rattus norvegicus)


name: 2 H(+)(out) + menaquinol-8 => 2 H(+)(in) + H2 + menaquinone-8


name: a fatty acylamide + H2O = a fatty acid + NH4(+)


name: (2S)-sakuranetin + S-adenosyl-L-methionine = (2S)-naringenin 4',7-dimethyl ether + H(+) + S-adenosyl-L-homocysteine


name: CLCN4/5/6 exchange Cl- for H+ (Bos taurus)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)


name: Activated FGFR3:p-FRS bind to PPTN11 (Canis familiaris)


name: dihydroferulate + NAD(+) => (E)-ferulate + H(+) + NADH


name: Phosphorylation of APC component of the destruction complex (Caenorhabditis elegans)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Mus musculus)


name: H(+) + N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP => [hyaluronan](n) + UDP-N-acetyl-alpha-D-glucosamine


name: alpha-D-glucose + ATP = ADP + alpha-D-glucose 6-phosphate + H(+)


name: Dual mechanism MAPK inhibitors bind MAPKs (Mus musculus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Danio rerio)


name: 1-hydroxyphenazine + CO2 + H2O + NAD(+) => 2 H(+) + NADH + O2 + phenazine-1-carboxylate


name: a (2S)-2-hydroxycarboxylate + O2 => a 2-oxocarboxylate + H2O2


name: Beclin-1 complex translocates to the ER (Bos taurus)


name: 4-hydroxy-3-all-trans-decaprenylbenzoate + H(+) = 2-all-trans-decaprenylphenol + CO2


name: 4-aminobutanoate + L-histidine => H2O + L-homocarnosine


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Homo sapiens)


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Xenopus tropicalis)


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Sus scrofa)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 7-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: (-)-vetispiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + solavetivone


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Rattus norvegicus)


name: Active FLT3 binds to SYK (Canis familiaris)


name: Indirect recruitment of GAB2 to p-KIT (Sus scrofa)


name: PTPMT1 dephosphorylates PGP to PG (Homo sapiens)


name: (5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP(+) <=> 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + H(+) + NADPH


name: 5alpha-pregnane-3,20-dione + NADP(+) <=> H(+) + NADPH + progesterone


name: SRXN1 reduces hyperoxidized PRDX1 dimer (Bos taurus)


name: anthranilate + malonyl-CoA <=> CoA + N-malonylanthranilate


name: (6R)-5,10-methenyltetrahydrofolate + H2O => (6R)-10-formyltetrahydrofolate + H(+)


name: Neuropeptide S receptor binds neuropeptide S (Gallus gallus)


name: H(+)(in) + thymidine(in) = H(+)(out) + thymidine(out)


name: ASC binds Caspase-8 complex (Rattus norvegicus)


name: 12-methyloctadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-(11-methylheptadecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Caenorhabditis elegans)


name: a 3',5'-unsubstituted flavanone + O2 + reduced [NADPH--hemoprotein reductase] => a 3'-hydroxy,5'-unsubstituted flavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O <=> 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: 4-hydroxyestrone + NH4(+) + O2 = 2 H(+) + 2 H2O + pyridinestrone carboxylate


name: (2S,4S,5S)-2-amino-6-(3,4-dihydroxyphenyl)-4-hydroxy-5-(methylamino)hexanoyl-[peptidyl-carrier protein] + O2 = (2S,4S)-2-amino-4-[(3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl]-4-hydroxybutanoyl-[peptidyl-carrier protein] + H2O2


name: RFC binding displaces Pol Alpha on the C-strand of the telomere (Homo sapiens)