name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O <=> 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Canis familiaris)


name: NOTCH1 HD+PEST domain mutants are cleaved by ADAM10/17 irrespective of ligand binding (Homo sapiens)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Homo sapiens)


name: D-threo-isocitrate + NADP(+) <=> (S)-oxalosuccinate + H(+) + NADPH


name: GPETA is hydrolyzed to ETA and G3P by GPCPD1 (Homo sapiens)


name: Interaction of GPVI and FceRI gamma (Sus scrofa)


name: Activated FGFR3 binds PLCG1 (Drosophila melanogaster)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Dictyostelium discoideum)


name: 1-alkenyl-2-acylglycerol choline phosphotransferase activity


name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) (Gallus gallus)


name: phosphorelay response regulator activity


name: 12alpha,13alpha-dihydroxyfumitremorgin C + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => fumitremorgin C + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: DDIT4 binds 14-3-3 dimer (Gallus gallus)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Danio rerio)


name: JAK2 is phosphorylated, activated (Bos taurus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + sn-glycerol 3-phosphate


name: 2-oxoglutarate + a flavanone + O2 = a flavone + CO2 + H2O + succinate


name: (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Rattus norvegicus)


name: H2O + N-formimidoyl-L-aspartate = N-formyl-L-aspartate + NH4(+)


name: 2-methylbutyronitrile + H(+) + NADPH + O2 => 2-hydroxy-2-methylbutanenitrile + H2O + NADP(+)


name: phycoerythrobilin-L-cysteinyl(84)-[C-phycoerythrin beta-subunit] => (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[C-phycoerythrin beta-subunit]


name: MTMR8 binds MTMR9 (Dictyostelium discoideum)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Bos taurus)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + succinate => 1-O-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Rattus norvegicus)


name: TRIM21 ubiquitinates SQSTM1 (Danio rerio)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Saccharomyces cerevisiae)


name: RUNX1 binds the core TAL1 complex (Mus musculus)


name: Phosphorylated PKN1 binds androgen receptor (AR) (Canis familiaris)


name: 4-O-deacetylvindoline + acetyl-CoA = CoA + vindoline


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(8)-citryl-spermidine => H(+) + holo-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8)-citryl-spermidine


name: PAK1 phosphorylates FLNA (Dictyostelium discoideum)


name: Elongating transcript encounters a lesion in the template (Mus musculus)


name: (S)-nicotine + NADPH + O2 => H2O + NADP(+) + trans-(S)-nicotine N(1')-oxide


name: 3-oxotetracosanoyl-CoA + H(+) + NADH => (3R)-hydroxytetracosanoyl-CoA + NAD(+)


name: an N-acetylarylalkylamine + H2O => acetate + an aralkylamine


name: RNASEs bind bacterial LPS, PGN (Mus musculus)


name: AMP + diphosphate + marinoloyl-CoA C => ATP + CoA + marinolate C


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine = 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 4 H(+) + 3 L-methionine


name: "anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase"


name: Association of procollagen type V (Xenopus tropicalis)


name: PAK binds RAC and bPIX (Rattus norvegicus)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Xenopus tropicalis)


name: a beta-D-glucuronoside + H2O => an alcohol + D-glucuronate


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Mus musculus)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Plasmodium falciparum)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate <=> alpha-humulene + diphosphate


name: Active G alpha (z) binds RGS proteins (Mus musculus)


name: OCT2 mediates tubular secretion of organic cations in the kidney (Sus scrofa)


name: 10-oxo-(11E)-octadecenoate + H(+) + NADH <=> 10-hydroxy-(11E)-octadecenoate + NAD(+)


name: ERBB2 binds TKIs (Caenorhabditis elegans)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Saccharomyces cerevisiae)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-sn-glycerol + H(+) + phosphoethanolamine


name: succinate-semialdehyde dehydrogenase [NAD(P)+] activity


name: SDH complex dehydrogenates succinate (Sus scrofa)


name: (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate(in) + L-histidyl-[protein] => (2R)-2-O-(alpha-D-mannosyl)-glycerate(out) + N(pros)-phospho-L-histidyl-[protein]


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Drosophila melanogaster)


name: DNA nucleases bind monoubiquitinated ID2 complex (Canis familiaris)


name: DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA (Homo sapiens)


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Plasmodium falciparum)


name: ERCC8 (CSA) binds stalled RNA Pol II (Rattus norvegicus)


name: L-2,4-diaminobutanoate + pyruvate => L-alanine + L-aspartate 4-semialdehyde


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Homo sapiens)


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Mus musculus)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Xenopus tropicalis)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Xenopus tropicalis)


name: H2O + kaempferol 3-O-beta-D-glucoside <=> beta-D-glucose + kaempferol


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O


name: 21-hydroxyprogesterone + H(+) + NADPH <=> 5beta-dihydrodeoxycorticosterone + NADP(+)


name: Spherical HDL binds C and E apolipoproteins (Mus musculus)


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Bos taurus)


name: 3,4-dihydroxybenzoate + UDP-alpha-D-glucose => 1-O-(3,4-dihydroxy-benzoyl)-beta-D-glucose + UDP


name: Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Mus musculus)


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Rattus norvegicus)


name: FPR is a receptor for formyl peptides (Mus musculus)


name: D-mannitol 1-phosphate + NADP(+) <=> D-mannose 6-phosphate + H(+) + NADPH


name: Phosphorylation of cPLA2 by ERK-2 (Homo sapiens)


name: Cargo Recognition And Sorting (Sus scrofa)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADH + O2 + toluene-4-sulfonate <=> 4-(hydroxymethyl)benzenesulfonate + H2O + NAD(+)


name: D-cysteine + H2O + O2 = 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)


name: an adenosine in tRNA + S-adenosyl-L-methionine <=> an N(1)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: PLC-gamma1 hydrolyses PIP2 (Dictyostelium discoideum)


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Canis familiaris)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Sus scrofa)


name: RHOD GAPs stimulate RHOD GTPase activity (Sus scrofa)


name: (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) => benzoate + H(+) + NADH + O2


name: (R)-3-hydroxy-(13Z)-eicosenoyl-CoA <=> (2E,13Z)-eicosadienoyl-CoA + H2O


name: sphinganine 1-phosphate(out) => sphinganine 1-phosphate(in)


name: EP2 and EP4 receptors can bind PGE2 (Rattus norvegicus)


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Bos taurus)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: (2E)-decenal + H(+) + NADPH => decanal + NADP(+)


name: (1R,4S)-menthone + NADP(+) <=> (R)-pulegone + H(+) + NADPH


name: 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+) => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 24 H(+) + 8 malonyl-CoA + 16 NADPH


name: ATP + fluconazole(in) + H2O => ADP + fluconazole(out) + H(+) + phosphate


name: GSDMD (1-275) binds bacterial cardiolipin (Mus musculus)


name: CASP8 cleaves N4BP1 at D424, D490 (Bos taurus)


name: D-arabinono-1,4-lactone + H2O = D-arabinonate + H(+)


name: Kinetochore capture of astral microtubules (Xenopus tropicalis)


name: aminopropylcadaverine + H(+) + S-methyl-5'-thioadenosine => cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine


name: L,L-cystathionine <=> 2-aminobut-2-enoate + L-cysteine


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: H(+) + orotidine 5'-phosphate => CO2 + UMP


name: Binding of EGF to ligand-responsive EGFR mutants (Homo sapiens)


name: p-S215 FOXO3 translocates to the nucleus (Homo sapiens)


name: 4-maleylacetoacetate + H(+) => homogentisate + O2


name: ATP + L-isoleucine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate <=> ADP + dapdiamide B + H(+) + phosphate


name: Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize (Homo sapiens)


name: SCF(SKP2) complex binds RUNX2 (Danio rerio)


name: 5,6,7,8-tetrahydromethanopterin + ATP + L-glutamate = 5,6,7,8-tetrahydrosarcinapterin + ADP + H(+) + phosphate


name: AGT(34-41) binds to AGTR2 (Rattus norvegicus)


name: decanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-decenoyl-CoA + reduced [electron-transfer flavoprotein]


name: H2O + N,N',N''-triacetylchitotriono-1,5-lactone <=> H(+) + N,N',N''-triacetylchitotrionate


name: 2 H(+) + 2 NADPH + 2 O2 + tetracenomycin A2 = H2O + 2 NADP(+) + tetracenomycin C


name: PLA1A hydrolyses PS to 2-acyl LPS (Mus musculus)


name: (13Z)-docosenamide + H2O = (13Z)-docosenoate + NH4(+)


name: Beclin-1 complex phosphorylates PtdIns (Schizosaccharomyces pombe)


name: S-methyl-5-thio-D-ribulose 1-phosphate = S-methyl-1-thio-D-xylulose 5-phosphate


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Caenorhabditis elegans)


name: alpha-D-glucose 1-phosphate + H(+) + UTP <=> diphosphate + UDP-alpha-D-glucose


name: aldehydo-D-glucuronate(in) + H(+)(in) <=> aldehydo-D-glucuronate(out) + H(+)(out)


name: eIF5B:GTP is hydrolyzed and released (Saccharomyces cerevisiae)


name: indole + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase]


name: NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) (Homo sapiens)


name: Direct recruitment of PI3K to p-KIT (Gallus gallus)


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O <=> beta-D-glucose + N-hexadecanoylsphing-4-enine


name: mRNA3 is translated to protein 3a (Homo sapiens)


name: 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase] => cholesta-5,7-dien-3beta,25-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Group 3 - Selective Cl- transport (Bos taurus)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Caenorhabditis elegans)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Canis familiaris)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Xenopus tropicalis)


name: L-cysteinyl-tRNA(Cys) + phosphate => H(+) + hydrogen sulfide + O-phospho-L-seryl-tRNA(Cys)


name: 2',3'-cyclophospho-UMP + H2O <=> 3'-UMP + H(+)


name: GTP-binding activates eEF2 (Danio rerio)


name: ProGIP translocates from the ER Lumen to secretory granules (Gallus gallus)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 <=> 4-[(E)-2-isocyanoethenyl]phenol + 2 CO2 + H2O + succinate


name: ATP + H2O + spermine(out) <=> ADP + H(+) + phosphate + spermine(in)


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Mus musculus)


name: RHOG GEFs activate RHOG (Canis familiaris)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)


name: NH4(+) + uridine(8) in tRNA => cytidine(8) in tRNA + H(+) + H2O


name: 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + H(+) + UDP => apigenin 7-O-beta-D-glucoside + UDP-alpha-D-apiose


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Canis familiaris)


name: 2'-hydroxybiphenyl-2-sulfinate + H2O => biphenyl-2-ol + H(+) + sulfite


name: COQ3 methylates DHDB (Xenopus tropicalis)


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate => ectocarpin A + H2O


name: TRIM28 (KAP1) binds KRAB-ZFP in KRAB-ZFP:retroelement chromatin (Homo sapiens)


name: PEBP1 binds activated RAF1 (Xenopus tropicalis)


name: TRIM33 monoubiquitinates SMAD4 (Mus musculus)


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR (Rattus norvegicus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: bradykinin + H2O => bradykinin(1-7) + L-Phe-L-Arg


name: Active ALK dimer binds IRS1 (Canis familiaris)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Saccharomyces cerevisiae)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose <=> an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Gallus gallus)


name: H2O + L-isoleucine + O2 = (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: LC3 de-lipidation by ATG4 (Mus musculus)


name: "NAD(P)H sulfur oxidoreductase (CoA-dependent)"


name: 3-methylphenol + O2 + reduced [NADPH--hemoprotein reductase] <=> 3-hydroxybenzyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Xenopus tropicalis)


name: DCP1-DCP2 complex decaps mRNA (Saccharomyces cerevisiae)


name: METAP1/2 demethylates GNAT1 (Schizosaccharomyces pombe)


name: 1-octadecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol


name: 15-oxoprostaglandin E2 + H(+) + NADH => 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(+)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Canis familiaris)


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Rattus norvegicus)


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Homo sapiens)


name: Dopa is oxidized to dopaquinone by TYR (Rattus norvegicus)


name: (10E)-octadecenoate + H2O = 10-hydroxyoctadecanoate


name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Gallus gallus)


name: dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H(+) + N(omega)-(alpha-L-rhamnosyl)-L-arginyl-[protein]


name: 16alpha,17alpha-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP => 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate


name: O2 + reduced [NADPH--hemoprotein reductase] + vinorine => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + vomilenine


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Phosphorylation of Platelet Sec-1 (Gallus gallus)


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Mus musculus)


name: RHOB binds effectors at the plasma membrane (Drosophila melanogaster)


name: a neolactoside IV(3)-alpha-NeuGc-nLc4Cer + UDP-N-acetyl-alpha-D-galactosamine <=> a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer + H(+) + UDP


name: 17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] => 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: H(+) + NAD(+) + reduced 2[4Fe-4S]-[ferredoxin] <=> NADH + oxidized 2[4Fe-4S]-[ferredoxin]


name: NOX3 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)


name: dCDP(out) + UTP(in) = dCDP(in) + UTP(out)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Gallus gallus)


name: Dimeric TGF-beta-1 binds to the receptor (Sus scrofa)


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Rattus norvegicus)


name: IL21 receptor STAT phosphorylation (Danio rerio)


name: (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA + H(+) + NADPH <=> (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + NADP(+)


name: STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Xenopus tropicalis)


name: Transport of GAG to the Plasma Membrane (Homo sapiens)


name: P-selectin binds P-selectin ligand (Homo sapiens)


name: H(+) + N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine => guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine


name: Dimerization of overexpressed FGFR2 (Homo sapiens)


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Rattus norvegicus)


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2 <=> 18S-resolvin E2 + A + H2O


name: (+)-dehydrodiconiferyl acid ketone + a quinone + H2O = (+)-dehydrodiconiferyl acid carboxylate + a quinol + H(+)


name: 5alpha-androst-1-ene-3,17-dione + A <=> AH2 + androsta-1,4-diene-3,17-dione


name: ERK5 translocates to the nucleus (Saccharomyces cerevisiae)


name: 6-sulfo-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol


name: TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)


name: PDE3A hydrolyses cAMP to AMP (Rattus norvegicus)


name: PTEN dephosphorylates PIP3 (Dictyostelium discoideum)


name: H2O + S-adenosyl-L-homocysteine <=> adenosine + L-homocysteine


name: Formation of CRY:PER:Kinase complex (Homo sapiens)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Saccharomyces cerevisiae)


name: high-affinity copper ion transmembrane transporter activity


name: PP2A-PP2R5C dephosphorylates MDM2 (Mus musculus)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Saccharomyces cerevisiae)


name: glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Homo sapiens)


name: HCFC1 binds SET1A complex (Caenorhabditis elegans)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Danio rerio)


name: (R)-carnitine + octanoyl-CoA = CoA + O-octanoyl-(R)-carnitine


name: (2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] = biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin]


name: MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Mus musculus)


name: IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 (Gallus gallus)


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Mus musculus)


name: Phosphorylation of IRS (Xenopus tropicalis)


name: dimethylallyl diphosphate + L-tryptophan => 4-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: glutathione + S-methyl-1-thio-D-xylulose 5-phosphate = 1-deoxy-D-xylulose 5-phosphate + S-(methylsulfanyl)glutathione


name: SENP1,2,5 proteolytically process SUMO1 (Schizosaccharomyces pombe)


name: 3-oxopropanoate + L-alanine => beta-alanine + pyruvate


name: Budding of COPII coated vesicle (Danio rerio)


name: Autophosphorylation of PAK (Mus musculus)


name: ADP + D-fructose(in) + H(+) + phosphate => ATP + D-fructose(out) + H2O


name: RAC2 binds effectors at the phagocytic vesicle membrane (Gallus gallus)


name: GRB2:SOS1 binds to HBEGF:p-Y-EGFR (Mus musculus)


name: L-seryl-[EGF-like domain protein] + UDP-alpha-D-glucose = 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Xenopus tropicalis)


name: 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + neopikromycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PP2A-PP2R5C dephosphorylates MDM2 (Rattus norvegicus)


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Sus scrofa)


name: H2O + inosine => D-ribose + hypoxanthine


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Drosophila melanogaster)


name: 2-(1-hydroxyethyl)thiamine diphosphate + 2-oxobutanoate = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + thiamine diphosphate


name: Phosphorylation of SHC by SYK kinase (Homo sapiens)


name: H(+) + NADH + succinate semialdehyde => 4-hydroxybutanoate + NAD(+)


name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Bos taurus)


name: 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Xenopus tropicalis)


name: Formation of hydroxylysyl-pyridinoline cross-links (Bos taurus)


name: Activated MET binds GAB1 (Rattus norvegicus)


name: Noradrenaline clearance from the synaptic cleft (Gallus gallus)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Bos taurus)


name: a steroid + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> an 11beta-hydroxysteroid + H2O + 2 oxidized [adrenodoxin]


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + cholesterol


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-valine + O2 = 2-dehydro-D-glucose + H2O2 + L-valine


name: an N-acylneuraminate + CTP = a CMP-N-acyl-beta-neuraminate + diphosphate


name: Formation of the SCF-FBXL7 complex (Homo sapiens)


name: alpha-humulene + O2 + reduced [NADPH--hemoprotein reductase] => 10-hydroxy-alpha-humulene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activation of Cdc42 by pVav1 (Gallus gallus)


name: 23S rRNA (adenine(2030)-N(6))-methyltransferase activity


name: MECP2:SIN3A complex binds OPRM1 gene promoter (Homo sapiens)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] => 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin]


name: nucleoside transmembrane transporter activity


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Gallus gallus)


name: Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Bos taurus)


name: a ganglioside GM1 + H2O = an N-acyl-sphingoid base + beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-D-Glc


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 19-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: (3R)-hydroxybutanoate trimer + H2O <=> (3R)-hydroxybutanoate dimer + (R)-3-hydroxybutanoate + H(+)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Caenorhabditis elegans)


name: ALOX5 oxidises EPA to 5-HEPE (Bos taurus)


name: (11R)-dihydroartemisinate + 2 H(+) + NADPH => (11R)-dihydroartemisinic aldehyde + H2O + NADP(+)


name: PIAS4 SUMOylates TOP2A with SUMO2,3 (Gallus gallus)


name: USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Mus musculus)


name: a 2-acyl-4-prenylphloroglucinol + dimethylallyl diphosphate <=> a 2-acyl-4,6-diprenylphloroglucinol + diphosphate


name: STUB1 ubiquitinates RIPK3 at K55, K363 (Homo sapiens)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)


name: 2'-phospho-[ligated tRNA] + NAD(+) <=> ADP-alpha-D-ribose 1'',2''-cyclic phosphate + mature tRNA + nicotinamide


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Canis familiaris)


name: galactitol 1-phosphate + NAD(+) = H(+) + keto-L-tagatose 6-phosphate + NADH


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Caenorhabditis elegans)


name: NFE2 binds the beta globin locus control region (Canis familiaris)


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Danio rerio)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 3-octadecanoyl-sn-glycerol <=> 1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + CoA


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Homo sapiens)


name: PKA phosphorylates DARPP-32 on Thr34 (Bos taurus)


name: 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 H(+) + 2 S-adenosyl-L-homocysteine => cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Canis familiaris)


name: atRAL is reduced to atROL (Gallus gallus)


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Saccharomyces cerevisiae)


name: (R)-6-hydroxynicotine + H2O + O2 => 6-hydroxypseudooxynicotine + H2O2


name: 12-phosphooxy-(9E)-octadecenoate + H2O = 12-hydroxy-(9E)-octadecenoate + phosphate


name: PAO:FAD oxidises NASPM to PTCN (Bos taurus)


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Bos taurus)


name: glyceollin II + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase]


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Drosophila melanogaster)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Danio rerio)


name: 1-(7Z,10Z,13Z,16Z-docosatetraenoyl)-glycerol + H2O => (7Z,10Z,13Z,16Z)-docosatetraenoate + glycerol + H(+)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Homo sapiens)


name: (3S)-3-hydroxybutanoyl-CoA + H2O = (S)-3-hydroxybutanoate + CoA + H(+)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Caenorhabditis elegans)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Homo sapiens)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Rattus norvegicus)


name: A + H2O + N-methyl-L-glutamate <=> AH2 + formaldehyde + L-glutamate


name: Interaction of E3 ligase with ISG15:E2 complex (Rattus norvegicus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: SESN1,2,3 bind overoxidized PRDX1 (Drosophila melanogaster)


name: 2-hydroxydodecanoate + H2O2 <=> 2,3-dihydroxydodecanoate + H2O


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Homo sapiens)


name: DP2 receptor can bind PGD2 (Mus musculus)


name: fumarate(out) + 3 H(+)(out) = fumarate(in) + 3 H(+)(in)


name: Insertion of MHC II:Ii complex in to the plasma membrane (Canis familiaris)


name: formate + N-terminal L-methionyl-[peptide] => H2O + N-terminal N-formyl-L-methionyl-[peptide]


name: a 4'-hydroxyisoflavone + S-adenosyl-L-methionine <=> a 4'-methoxyisoflavone + H(+) + S-adenosyl-L-homocysteine


name: ATP + CoA + pentadecanoate => AMP + diphosphate + pentadecanoyl-CoA


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Bos taurus)


name: CYP79F1 dihomomethionine monooxygenase activity


name: 2 H2O + L-1-piperideine-6-carboxylate + NAD(+) = H(+) + L-2-aminoadipate + NADH


name: CHGA-derived peptide binds the bacterial cell surface (Bos taurus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV (Rattus norvegicus)


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate + NH4(+) => 2-amino-2-deoxy-D-gluconate 6-phosphate


name: dTDP-6-deoxy-beta-L-talose + NADP(+) <=> dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH


name: Localization of CBL:GRB2 to the membrane (Drosophila melanogaster)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Rattus norvegicus)


name: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Sus scrofa)


name: DARPP-32 is dephosphorylated on Thr75 by PP2A (Homo sapiens)


name: (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] <=> 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Danio rerio)


name: Re-integration of insulin receptor into plasma membrane (Xenopus tropicalis)


name: MET phosphorylates SHC1-2 (Canis familiaris)


name: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Homo sapiens)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Rattus norvegicus)


name: 4-O-beta-D-glucosyl-trans-ferulate + H2O <=> 4-O-beta-D-glucosyl-vanillin + acetate


name: a sphingomyelin(in) <=> a sphingomyelin(out)


name: 9H-fluoren-9-ol + NADP(+) = 9H-fluoren-9-one + H(+) + NADPH


name: Cleavage of uracil by Uracil-glycosylase (Gallus gallus)


name: p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Caenorhabditis elegans)


name: chloride + FADH2 + O2 + tetracycline = 7-chlorotetracycline + FAD + H(+) + 2 H2O


name: O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + H(+) + UDP


name: 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) => 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: H2O + S-formylglutathione <=> formate + glutathione + H(+)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Drosophila melanogaster)


name: (2Z,6Z)-farnesyl diphosphate => diphosphate + germacrene C


name: (S)-ureidoglycolate + urea => allantoate + H2O


name: Nociceptin receptor binds to nociceptin (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + CDP-choline <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(in) + ATP + H2O


name: 4-methylumbelliferone beta-D-glucuronate(in) + ATP + H2O <=> 4-methylumbelliferone beta-D-glucuronate(out) + ADP + H(+) + phosphate


name: 1-acyl-2-(9Z,12Z-octadecadienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 1-acyl-2-(9Z,12Z,15Z-octadecatrienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Homo sapiens)


name: Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex (Homo sapiens)


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Canis familiaris)


name: factor V -> factor Va + factor V activation peptide (Gallus gallus)


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Homo sapiens)


name: AcK-NFE2L2 and MAFK bind the GSTA1 gene (Homo sapiens)


name: Galpha-olf:GTP binds to adenylate cyclase and activates it (Canis familiaris)


name: Formation of dehydro-lysinonorleucine cross-links (Homo sapiens)


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Sus scrofa)


name: SLC19A2/3 transport extracellular THMN to cytosol (Sus scrofa)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Danio rerio)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Danio rerio)


name: β-blockers bind ADRB1,2,3 (Mus musculus)


name: HDAC6 deacetylates microtubules (Canis familiaris)


name: ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA (Homo sapiens)


name: glycylglycyl-L-isoleucine(out) + H(+)(out) = glycylglycyl-L-isoleucine(in) + H(+)(in)


name: Autocatalytic activation of MMP3 (Canis familiaris)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Sus scrofa)


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Sus scrofa)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Xenopus tropicalis)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Drosophila melanogaster)


name: CoA + H(+) + N-hexadecanoyl-taurine => hexadecanoyl-CoA + taurine


name: columbamine + S-adenosyl-L-methionine => H(+) + palmatine + S-adenosyl-L-homocysteine


name: structural constituent of presynaptic actin cytoskeleton


name: 3-sulfino-L-alanine(in) + H(+)(out) + L-glutamate(out) => 3-sulfino-L-alanine(out) + H(+)(in) + L-glutamate(in)


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)


name: melibiose transmembrane transporter activity


name: 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + CoA <=> (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> 1,4-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: "alcohol-forming fatty acyl-CoA reductase"


name: Cleavage and polyadenylation of Intronless Pre-mRNA (Sus scrofa)


name: 2-oxoglutarate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Sus scrofa)


name: RAC2 translocates to the mitochondrial membrane (Caenorhabditis elegans)


name: 2-oxoglutarate + putrescine = 1-pyrroline + H2O + L-glutamate


name: a (2S,3R)-flavan-3-ol + 2 NADP(+) => an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH


name: decanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] = CoA + H(+) + N(6)-decanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: H(+) + L-serine + octadecanoyl-CoA <=> 3-oxoeicosasphinganine + CO2 + CoA


name: hexanoate + sphinganine => H2O + N-hexanoyl-sphinganine


name: BOD1L1 binds SET1A complex (Mus musculus)


name: (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase] <=> (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADPH + sulfoacetaldehyde => 2-hydroxyethane-1-sulfonate + NADP(+)


name: Activated NOD1 oligomerizes (Xenopus tropicalis)


name: Elongation Of The Telomeric Chromosome End (Sus scrofa)


name: 4-hydroxybenzoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => benzoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Formation of DRIP coactivator complex (Homo sapiens)


name: Defective CYP11B2 does not oxidise CORST (Homo sapiens)


name: 4-hydroxybenzoate + all-trans-octaprenyl diphosphate => 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate


name: 4alpha-methyl-5alpha-cholest-7-en-3-one + H(+) + NADPH => 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP(+)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O = (9Z)-octadecenoate + 1,3-dihexadecanoylglycerol + H(+)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B3)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Sus scrofa)


name: acetyl-CoA + ergosta-5,7,22,24(28)-tetraen-3beta-ol => CoA + ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate


name: CTLH E3 ligase ubiquitinates PKM-1 (Rattus norvegicus)


name: factor Va + factor Xa -> Va:Xa complex (prothrombinase) (Canis familiaris)


name: 2 H(+) + O2 + rifamycin B <=> H2O2 + rifamycin O


name: Formation of VAF (virus-activated factor) complex (Bos taurus)


name: 4-O-methylrhodomycin D + H2O <=> 10-carboxy-13-deoxydaunorubicin + H(+) + methanol


name: BRD7 promotes EP300-mediated acetylation of TP53 (Drosophila melanogaster)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Sus scrofa)


name: ATP + L-threonine + tRNA(Thr) => AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + 2 H2O => 2 a carboxylate + 2 H(+) + sn-glycerol 3-phosphocholine


name: 5-pyridoxolactone + H(+) + NADH => isopyridoxal + NAD(+)


name: H(+) + rebaudioside D + UDP => rebaudioside A + UDP-alpha-D-glucose


name: TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Mus musculus)


name: SRC-1 bound to ARRB2 is not activated (Canis familiaris)


name: Recruitment of VAV and BTK to p-SLP-76 (Xenopus tropicalis)


name: baicalein + UDP-alpha-D-glucuronate => baicalin + UDP


name: Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Canis familiaris)


name: HSD17B3-like proteins reducde ANDST to TEST (Drosophila melanogaster)


name: STING ubiquitination by TRIM32 or TRIM56 (Homo sapiens)


name: (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = glyceollin II + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: USP25 deubiquitinates DDX58 (Saccharomyces cerevisiae)


name: coenzyme M-coenzyme B heterodisulfide + methane => coenzyme B + methyl-coenzyme M


name: Defective CYP2R1 does not 25-hydroxylate vitamin D (Homo sapiens)


name: PIN1 binds phosphorylated PIP4K2B (Gallus gallus)


name: (S)-1-pyrroline-5-carboxylate + H(+) + H2O + malonyl-CoA = (2S,5S)-5-carboxymethylproline + CO2 + CoA


name: (3R)-3-hydroxybutanoyl-CoA => (2E)-butenoyl-CoA + H2O


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Homo sapiens)


name: beta-alanine(out) + L-alanine(in) => beta-alanine(in) + L-alanine(out)


name: sequestered tissue factor -> tissue factor (Gallus gallus)


name: G beta-gamma complex and PIP3 recruit BTK to membrane (Homo sapiens)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Bos taurus)


name: (2R,3S)-homoisocitrate <=> cis-homoaconitate + H2O


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Mus musculus)


name: sulfate adenylyltransferase (ADP) activity


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Dictyostelium discoideum)


name: acetyl-CoA + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine => CoA + H(+) + UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose


name: ATP + sedoheptulose = ADP + D-sedoheptulose 7-phosphate + H(+)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Homo sapiens)


name: FLIP(L) and procaspase-8 form heterodimer (Sus scrofa)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)


name: A + semiviriditoxin => AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate


name: N-cyclohexylformamide = cyclohexyl isocyanide + H2O


name: a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate => 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2


name: FNTB inhibitors bind FNTA:FNTB (Dictyostelium discoideum)


name: (S)-stylopine + S-adenosyl-L-methionine <=> (S)-cis-N-methylstylopine + S-adenosyl-L-homocysteine


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Caenorhabditis elegans)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Rattus norvegicus)


name: TGFBR3 phosphorylation by TGFBR2 complex (Danio rerio)


name: ATXN3 binds polyUb-PARK2 (Canis familiaris)


name: Active PLC-gamma1 dissociates from EGFR (Mus musculus)


name: SLC22A1 transports Cipro into renal cell (Xenopus tropicalis)


name: carbamoyl phosphate + ornithine => citrulline + orthophosphate (Xenopus tropicalis)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Bos taurus)


name: Gbeta:gamma activation of PLC beta (Bos taurus)


name: chlorophyllide a + NADP(+) = H(+) + NADPH + protochlorophyllide a


name: SUMOylation of TOP2A with SUMO1 (Bos taurus)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Drosophila melanogaster)


name: NADP(+) + sn-glycerol 3-phosphate <=> D-glyceraldehyde 3-phosphate + H(+) + NADPH


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IIA => a 2-acyl-sn-glycero-3-phosphocholine + lipid IIB


name: [ribosomal protein S23]-trans-3-hydroxy-L-proline + CO2 + succinate => 2-oxoglutarate + [ribosomal protein S23]-L-proline + O2


name: GSTs transfer GSH to NAPQI to form APAP-SG (Canis familiaris)


name: SLC17A3-2 transports cytosolic urate to extracellular region (Dictyostelium discoideum)


name: NEIL1 cleaves thymine glycol from damaged DNA (Sus scrofa)


name: [5-(aminomethyl)-3-furyl]methyl phosphate + pyruvate => 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + L-alanine


name: ADP + H(+) + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] => ATP + N(6)-(D-psicosyl)-L-lysyl-[protein]


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Bos taurus)


name: TRIM21 ubiquitinates SQSTM1 (Rattus norvegicus)


name: Dephosphorylation of AKT by PP2A (Drosophila melanogaster)


name: 6alpha-hydroxy-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase] = 28-nortyphasterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: diglucosyl-enterobactin + UDP-alpha-D-glucose => H(+) + triglucosyl-enterobactin + UDP


name: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + AH2 + O2 => A + H2O + N(6)-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenosine(37) in tRNA


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Mus musculus)


name: (E,E)-sorbate + H(+) <=> (E)-1,3-pentadiene + CO2


name: Abortive initiation after formation of the first phosphodiester bond (Caenorhabditis elegans)


name: 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O = 2-glutaroyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: SORD tetramer oxidizes xylitol to D-xylulose (Mus musculus)


name: an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-cysteinylglycine + L-glutamate => an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H2O


name: Defective IDUA does not hydrolyse Heparan sulfate chain(1) (Homo sapiens)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Mus musculus)


name: AMP + H2O => IMP + NH4+ (AMPD) (Mus musculus)


name: TMEM129 polyubiquitinates HLA (MHC class I heavy chain) bound to cytomegalovirus US11 (Homo sapiens)


name: 4 Fe(III)-[cytochrome c] + hydrazine <=> 4 Fe(II)-[cytochrome c] + 4 H(+) + N2


name: (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) => catechol + H(+) + NADPH


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Rattus norvegicus)


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Canis familiaris)


name: Deletions of the AMER1 gene prevent expression of AMER1 protein (Homo sapiens)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)


name: RAC1,RAC2,RHOG activate PI3K (Homo sapiens)


name: POLZ elongates POLI-incorporated dNMP (Plasmodium falciparum)


name: 2 Fe(III)-[cytochrome c2] + NADPH <=> 2 Fe(II)-[cytochrome c2] + H(+) + NADP(+)


name: Nociceptin receptor binds to nociceptin (Mus musculus)


name: beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer + H(+) + UDP => a neolactoside IV(3)-beta-GlcNAc-nLc4Cer + UDP-alpha-D-galactose


name: phosphate(in) + 2 thiosulfate(out) => phosphate(out) + 2 thiosulfate(in)


name: ROCK activation by RHO (Drosophila melanogaster)


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Gallus gallus)


name: 2-aminopentane + H2O + NAD(+) <=> H(+) + NADH + NH4(+) + pentan-2-one


name: Synthesis of dolichyl-phosphate-glucose (Canis familiaris)


name: Exocytosis of specific granule membrane proteins (Danio rerio)


name: ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Homo sapiens)


name: Cleavage of lip22 to lip10 (Danio rerio)


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Saccharomyces cerevisiae)


name: PIAS1 SUMOylates SP3 with SUMO2 (Homo sapiens)


name: RHOD binds effectors at the endosome membrane (Rattus norvegicus)


name: (2E)-hexenoyl-CoA + H(+) + NADPH <=> hexanoyl-CoA + NADP(+)


name: Cleavage of Procaspase‑9 to caspase‑9 (Xenopus tropicalis)


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Gallus gallus)


name: SUCLG1/A2 cleaves succinyl-CoA (Danio rerio)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+) => a CDP-1,2-diacyl-sn-glycerol + myo-inositol


name: p-ERK phosphorylates WAVEs and ABI (Bos taurus)


name: (9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 4-amino-4-deoxyprephenate + NAD(+) <=> 3-(4-aminophenyl)pyruvate + CO2 + H(+) + NADH


name: peroxynitrite => nitric oxide + superoxide


name: (Z)-3-ureidoacrylate + H2O <=> (Z)-3-aminoacrylate + carbamate + H(+)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP => 1D-myo-inositol hexakisphosphate + ATP


name: beta-alanine + histamine => carcinine + H2O


name: cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Bos taurus)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Homo sapiens)


name: dehydroepiandrosterone 3-sulfate(out) <=> dehydroepiandrosterone 3-sulfate(in)


name: Association of Emi1 with Cdc20 (Gallus gallus)


name: L-phenylalanine(out) + Na(+)(out) => L-phenylalanine(in) + Na(+)(in)


name: 3'-phosphoadenylyl sulfate + 4-nitrophenol = 4-nitrophenyl sulfate + adenosine 3',5'-bisphosphate


name: Translocation of NFATC1:CaN:CaM to nucleus (Homo sapiens)


name: chorismate + NH4(+) <=> (2S)-2-amino-4-deoxychorismate + H2O


name: p-Y694-STAT5A, p-STAT5B dimerizes (Sus scrofa)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine-phospho-ribonucleoside in mRNA + H2O = (N(7)-methyl 5'-triphospho-guanosine)-guanosine + a 5'-end phospho-ribonucleoside in mRNA + H(+)


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Homo sapiens)


name: PA is converted to CDP-DAG by CDS2 (Danio rerio)


name: abacavir [extracellular] => abacavir [cytosol] (Gallus gallus)


name: 3'-phosphoadenylyl sulfate + 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] = 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: Binding of Syk tyrosine kinase (Canis familiaris)


name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Rattus norvegicus)


name: copper-nicotianamine transmembrane transporter activity


name: fumonisin B1 + 2 H2O <=> (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + 2 H(+) + 2 tricarballylate


name: 3'-phosphoadenylyl sulfate + beta-D-galactosyl-(1<->1)-sphing-4-enine = 6-O-sulfo-beta-D-galactosyl-(1<->1)-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)


name: RAR:RXR binds SUMO-CRABP2:atRA (Homo sapiens)


name: carbonyl sulfide + H2O <=> CO2 + H(+) + hydrogen sulfide


name: Cargo-carrying vesicles bud from the TGN (Homo sapiens)


name: 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine => H(+) + lipid A disaccharide (E. coli) + UDP


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-octadecyl-sn-glycero-3-phosphocholine <=> 1-O-octadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Canis familiaris)


name: 2 (S)-lactate(in) + prostaglandin E1(out) => 2 (S)-lactate(out) + prostaglandin E1(in)


name: (3Z)-decenoyl-[ACP] + H(+) + malonyl-[ACP] => 3-oxo-(5Z)-dodecenoyl-[ACP] + CO2 + holo-[ACP]


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Xenopus tropicalis)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: 1-hexadecanoyl-sn-glycerol + phosphate => 1-hexadecanoyl-sn-glycero-3-phosphate + H2O


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 20S,24S-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate <=> 11-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NOTCH1 PEST domain mutants coactivator complex binds CDK8:CCNC (Homo sapiens)


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 20S,24R-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-(methylamino)butanoate + H(+)


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate


name: Protein tyrosine phosphatases dephosphorylate NTRK3 (Homo sapiens)


name: ALD3A1 oxidises 4HPCP to CXPA (Danio rerio)


name: L-lysyl-[protein] + tetradecanoyl-CoA => CoA + H(+) + N(6)-tetradecanoyl-L-lysyl-[protein]


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Rattus norvegicus)


name: saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity


name: a menaquinone + sn-glycerol 3-phosphate = a menaquinol + dihydroxyacetone phosphate


name: HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Danio rerio)


name: ATRX:DAXX binds to subtelomeric chromosomal regions (Homo sapiens)


name: Tyrosinase oxidises tyrosine to dopaquinone (Homo sapiens)


name: JMJD6 demethylates Me2R3-histone H3 (Bos taurus)


name: CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Sus scrofa)


name: T1R2/T1R3 dimer is a sweet taste receptor (Mus musculus)


name: ATP + D-allose <=> ADP + D-allose 6-phosphate + H(+)


name: 3'-phosphoadenylyl sulfate + beta-D-Gal-(1<->1')-Cer = 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+)


name: CO2 + hydroxyclavatol + succinate => 2-oxoglutarate + clavatol + O2


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Dictyostelium discoideum)


name: glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 (Homo sapiens)


name: COQ3 methylates DHDB (Saccharomyces cerevisiae)


name: methyl-Co(III)-[dimethylamine-specific corrinoid protein] + methylamine => Co(I)-[dimethylamine-specific corrinoid protein] + dimethylamine + H(+)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Gallus gallus)


name: atROL binds RBP1 to form RBP1:atROL (Homo sapiens)


name: CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D (Danio rerio)


name: L-homoserine = 2-aminobut-2-enoate + H2O


name: (2E)-3-(3-hydroxyphenyl)prop-2-enoate + H(+) + NADH + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD(+)


name: 4-hydroxy-5-methyl-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA => 2 H(+) + hexadecanoyl-CoA + malonyl-CoA + methylmalonyl-CoA


name: 7-deoxyloganetate + UDP-alpha-D-glucose <=> 7-deoxyloganate + H(+) + UDP


name: 11,20-dihydroxysugiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 11-hydroxysugiol + O2 + reduced [NADPH--hemoprotein reductase]


name: Kinesin-5 is a homotetramer (Rattus norvegicus)


name: 1-(beta-D-galactosyl)-N-dodecanoylsphing-4-enine + cholesterol <=> cholesteryl 3-beta-D-galactoside + N-dodecanoylsphing-4-enine


name: ADP + H(+) + N-acetyl-D-glucosamine 6-phosphate => ATP + N-acetyl-D-glucosamine


name: HLCS biotinylates ACACA:Mn2+ (Xenopus tropicalis)


name: PGH2 is isomerised to PGE2 by PTGES (Danio rerio)


name: peregrinol diphosphate => (13R)-9,13-epoxylabd-14-ene + diphosphate


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Saccharomyces cerevisiae)


name: ATP + L-asparagine + tRNA(Asn) <=> AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Bos taurus)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Danio rerio)


name: a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GA1 (d18:1(4E)) + H(+) + UDP


name: a pyrimidine ribonucleoside 5'-phosphate + H2O <=> a pyrimidine nucleobase + D-ribose 5-phosphate


name: a 5'-end dephospho-ribonucleoside-RNA + ATP <=> a 5'-end 5'-phospho-ribonucleoside-RNA + ADP + H(+)


name: all-trans-beta-carotene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Casein kinase II phosphorylates PTEN (Dictyostelium discoideum)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Homo sapiens)


name: (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] => 1,2-dehydroreticuline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: COQ3 methylates DHDB (Rattus norvegicus)


name: PLC beta-mediated PIP2 hydrolysis (Xenopus tropicalis)


name: PD-1 binds B7DC and B7H1 (Canis familiaris)


name: RCC1 stimulates GDP to GTP exchange on RAN (Plasmodium falciparum)


name: ADH5 oxidises S-HMGSH to S-FGSH (Schizosaccharomyces pombe)


name: ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Gallus gallus)


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 => 7-epi-cylindrospermopsin + CO2 + succinate


name: EGFR phosphorylates GPNMB (Rattus norvegicus)


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Homo sapiens)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Dictyostelium discoideum)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Plasmodium falciparum)


name: (2E,10E)-dode-2,10-dicenoyl-CoA + H(+) + oxaloacetate => [4-(deca-1,8-diyl)-2,5-dioxo-2,5-dihydro-3-furanyl]acetate + CoA + H2O


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(N-acetyl-alpha-D-neuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: SMURF1 binds phosphorylated PARD6A (Danio rerio)


name: EPS15 and HGS bind CBL-monoubiquitinated MET engaged with Listeria InlB (Homo sapiens)


name: PI3K associates with phosphorylated GAB2 (Sus scrofa)


name: Formation of Pol zeta complex (Xenopus tropicalis)


name: Methionine sulfoxide is oxidised to methionine sulfone (Homo sapiens)


name: PRKCZ recruits RAS in response to estrogen stimulation (Drosophila melanogaster)


name: camphor + H(+) + NADH => borneol + NAD(+)


name: alpha-D-glucose 1-phosphate + O-phospho-L-seryl-[protein] => alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]


name: beta-alanine + L-arginine => 3-guanidinopropanoate + L-ornithine


name: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) => a very-long-chain 3-oxoacyl-CoA + H(+) + NADPH


name: Trans-homodimerization of Neurofascin (Canis familiaris)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-epicubenol + diphosphate


name: 5''-phosphoribostamycin + H2O = phosphate + ribostamycin


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) (Mus musculus)


name: PRKN binds p-S-Ub:MOM proteins (Schizosaccharomyces pombe)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Canis familiaris)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Mus musculus)


name: beta-cryptoxanthin + O2 => (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal


name: TRPV1 binds TRPV1 agonists (Homo sapiens)


name: 11alpha-hydroxy-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] => 11-oxo-beta-amyrin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Rap1 signal termination by Rap1GAPs (Drosophila melanogaster)


name: FN3K phosphorylates ketosamines (Mus musculus)


name: myricetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = H(+) + myricetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP


name: Superoxide reduces cytochrome c (Schizosaccharomyces pombe)


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Gallus gallus)


name: a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+) => a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol


name: Interaction of GRB2:SOS complex with p-SHC1 (Drosophila melanogaster)


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Gallus gallus)


name: Activated NOD1 oligomerizes (Rattus norvegicus)


name: estrone 3-sulfate + H2O <=> estrone + H(+) + sulfate


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Mus musculus)


name: Activation of Rap1 by cytosolic GEFs (Sus scrofa)


name: H2O + N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: Recruitment of PI3K to plasma membrane (Bos taurus)


name: Proteasomal clevage of exogenous antigen (Canis familiaris)


name: 3',5'-cyclic GMP(in) + ATP + H2O => 3',5'-cyclic GMP(out) + ADP + H(+) + phosphate


name: N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA => CoA + H(+) + N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein]


name: 1-hydroxylimonen-2-one + NADPH + O2 => 3-isopropenyl-6-oxoheptanoate + H2O + NADP(+)


name: NAGLU hydrolyses heparan chain(2) (Bos taurus)


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Caenorhabditis elegans)


name: L-gulono-1,4-lactone + O2 <=> H(+) + H2O2 + L-ascorbate


name: p-ERK phosphorylates WAVEs and ABI (Homo sapiens)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Homo sapiens)


name: The phagophore extends from the PIP3-enriched structure (Gallus gallus)


name: dihydrochelirubine + NADP(+) <=> chelirubine + NADPH


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Canis familiaris)


name: L1-EGFR trans-heterodimerization (Caenorhabditis elegans)


name: SeMet is converted to AdoSeMet by MAT (Plasmodium falciparum)


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Mus musculus)


name: 2-glyceryl-prostaglandin E2 => 2-glyceryl-prostaglandin H2


name: NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Gallus gallus)


name: (S)-2-amino-6-oxohexanoate + H2O2 + L-glutamate => H2O + L-saccharopine + O2


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Gallus gallus)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Xenopus tropicalis)


name: Phosphorylation of PKC theta (Caenorhabditis elegans)


name: Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL (Homo sapiens)


name: Collagen type V degradation by MMP2,9,10 (Mus musculus)


name: SHP2 dephosphorylates Tyr 992 on EGFR (Bos taurus)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)


name: uridine(55) in tRNA = pseudouridine(55) in tRNA


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + CoA => 1-O-alkyl-sn-glycero-3-phosphate + an acyl-CoA


name: [sulfur carrier]-SH + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + S-adenosyl-L-methionine = [sulfur carrier]-H + H(+) + L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + S-adenosyl-L-homocysteine


name: GTSE1 translocates to the nucleus (Gallus gallus)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA => 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: H2O + N-acyl-15-methylhexadecasphinganine = 15-methylhexadecasphinganine + a carboxylate


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Xenopus tropicalis)


name: SYK binds to p-Y65,Y76-FCER1G (Homo sapiens)


name: H(+) + NADH + O2 + protoasukamycin = 4-hydroxyprotoasukamycin + H2O + NAD(+)


name: GRK2 sequesters activated Gq (Rattus norvegicus)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Homo sapiens)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Sus scrofa)


name: adenosine + H(+) + H2O <=> inosine + NH4(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2 H2O <=> 2 H(+) + 2 hexadecanoate + sn-glycerol 3-phosphocholine


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Bos taurus)


name: Calcium Binds Troponin-C (Rattus norvegicus)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Dictyostelium discoideum)


name: ULK1 phosphorylates Beclin-1 (Saccharomyces cerevisiae)


name: PIAS1,3 SUMOylate MBD1 with SUMO1 (Xenopus tropicalis)


name: pregnenolone sulfate(out) <=> pregnenolone sulfate(in)


name: Egress of internalized antigen into cytosol from early endosome (Homo sapiens)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Sus scrofa)


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH => a long-chain fatty acid + n CO2 + (n+1) CoA + 2n NADP(+)


name: Dephosphorylation of CK2-modified condensin I (Homo sapiens)


name: YOD1 binds VCP (Dictyostelium discoideum)


name: aurachin C epoxide = 2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one


name: H2O + N-phosphocreatine = creatine + phosphate


name: SUMOylation of NOP58 with SUMO1 (Dictyostelium discoideum)


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)


name: norreticuline + S-adenosyl-L-methionine => H(+) + reticuline + S-adenosyl-L-homocysteine


name: CO2 + IDP + phosphoenolpyruvate => ITP + oxaloacetate


name: MTTP lipidates APOB-100, forming a pre-VLDL (Sus scrofa)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc6S derivative + GDP-beta-L-fucose => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc6S derivative + GDP + H(+)


name: 3-methyl-2-oxobutanoate + AH2 + NH4(+) => A + D-valine + H2O


name: (S)-corytuberine + 2 H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 => (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = a fatty acid + H(+) + sn-glycero-3-phospho-1D-myo-inositol


name: CoA + NAD(+) + sulfoacetaldehyde <=> H(+) + NADH + sulfoacetyl-CoA


name: 13-cis-retinol + a fatty acyl-CoA = 13-cis-retinyl ester + CoA


name: 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n) => NADP(+) + reduced coenzyme F420-(gamma-L-Glu)(n)


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Drosophila melanogaster)


name: protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity


name: H(+) + NADH + O2 + phenol = catechol + H2O + NAD(+)


name: ADBRK1,2 phosphorylate AVPR2 (Sus scrofa)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Homo sapiens)


name: (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein] = AMP + 2 H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: Cleavage of thymine by MBD4 glycosylase (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate => african-3-ene + diphosphate


name: Plasma membrane resorption (Canis familiaris)


name: THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Gallus gallus)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine => Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Canis familiaris)


name: MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Rattus norvegicus)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-ethanolamine <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA (Mus musculus)


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Sus scrofa)


name: (E)-sinapoyl-AMP + CoA => (E)-sinapoyl-CoA + AMP + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: H(+) + N-terminal S-hydroxy-S-oxy-L-cysteinyl-[protein] => N-terminal L-cysteinyl-[protein] + O2


name: Disulfiram covalently modifies Cys191 in GSDMD (Mus musculus)


name: H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein] => L-tyrosyl-[protein] + NAD(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine => 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin


name: GGPS1 hexamer transfers IPPP to DMAPP (Bos taurus)


name: Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch) (Homo sapiens)


name: EML4 recruits NUDC to mitotic spindle (Bos taurus)


name: NCAM1 interacts with T- and L-type VDCC (Homo sapiens)


name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Bos taurus)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-mannosaminouronate <=> beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: gibberellin A20 + S-adenosyl-L-methionine => gibberellin A20 methyl ester + S-adenosyl-L-homocysteine


name: sodium-dependent multivitamin transmembrane transporter activity


name: O2 + prosolanapyrone II => H2O2 + prosolanapyrone III


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: (19E)-geissoschizine + NADP(+) <=> 4,21-dehydrogeissoschizine + NADPH


name: (3S)-hydroxy-(9Z-octadecenoyl)-CoA => (2E,9Z)-octadecadienoyl-CoA + H2O


name: 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose = 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Caenorhabditis elegans)


name: IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Danio rerio)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Gallus gallus)


name: 4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NADP(+) <=> 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + H(+) + NADPH


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds


name: PTGS2 dimer binds PTGS2 inhibitors (Rattus norvegicus)


name: ESTG binds ESR2:chaperone complex (Homo sapiens)


name: H(+)(out) + lactose(in) = H(+)(in) + lactose(out)


name: Insertion of MHC II:Ii complex in to the plasma membrane (Sus scrofa)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-GDP


name: alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate + H(+) => alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O


name: atROL binds RBP1 (Caenorhabditis elegans)


name: OPLAH hydrolyses OPRO to L-Glu (Homo sapiens)


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Canis familiaris)


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Xenopus tropicalis)


name: AcK-NFE2L2 binds the PDGFA gene (Homo sapiens)


name: TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Homo sapiens)


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Bos taurus)


name: TPMT transfers CH3 from AdoMet to 6MP (Rattus norvegicus)


name: aculene D + CO2 + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => asperaculane E + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: Phosphorylated FOXO1A is excluded from the nucleus (Drosophila melanogaster)


name: ADP(in) + FAD(out) => ADP(out) + FAD(in)


name: H2O2 + N-acetyl-D-galactosamino-1,5-lactone => N-acetyl-D-galactosamine + O2


name: 3-oxooctadecanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyoctadecanoyl-[ACP] + NADP(+)


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)


name: (20S)-ginsenoside F1 + UDP-alpha-D-glucose <=> (20S)-ginsenoside Rg1 + H(+) + UDP


name: benzoyl-CoA + succinyl-CoA => (S)-2-benzoylsuccinyl-CoA + CoA


name: AFG3L2:SPG7 binds SMDT1 (EMRE) (Drosophila melanogaster)


name: Parkin binds Ub:UBE2N:UBE2V1 (Drosophila melanogaster)


name: AGFG1 binds VAMP7 (Drosophila melanogaster)


name: ALOX5 binds ALOX5 inhibitors (Canis familiaris)


name: Glucagon-like receptor 2 binds GLP2 (Mus musculus)


name: (E)-pent-2-en-1-ol + NADP(+) => (E)-2-pentenal + H(+) + NADPH


name: PTGS2 dimer oxidises DHA to 13-HDHA (Rattus norvegicus)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Homo sapiens)


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Mus musculus)


name: apo-[cytochrome c] + heme b => holo-[cytochrome c]


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Drosophila melanogaster)


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Mus musculus)


name: (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] => 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]


name: (2E)-15-methylhexadecenoyl-CoA + H(+) + NADPH <=> isoheptadecanoyl-coA + NADP(+)


name: SLC2A9 transports Fru, Glc, urate (Homo sapiens)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Gallus gallus)


name: 2 L-glutamate + NADP(+) <=> 2-oxoglutarate + H(+) + L-glutamine + NADPH


name: a globoside Gb4Cer + H2O = a globoside Gb3Cer + N-acetyl-beta-D-galactosamine


name: 2 H(+) + NADH + phosphonoacetate => H2O + NAD(+) + phosphonoacetaldehyde


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP-alpha-D-glucose => 2 H(+) + ternatin C5 + UDP


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Mus musculus)


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Saccharomyces cerevisiae)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Homo sapiens)


name: Cleavage of Procaspase-3 by the apoptosome (Drosophila melanogaster)


name: O2 + prostaglandin H1 + reduced [NADPH--hemoprotein reductase] = 19-hydroxyprostaglandin H1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p85 associates with both p-Nephrin and CD2AP (Homo sapiens)


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA => (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H2O


name: Ca impermeable AMPA receptor ligand binding (Drosophila melanogaster)


name: TBC1D25 (OATL1) binds ATG8 homologues (Rattus norvegicus)


name: 2 Fe(III)-[leghemoglobin] + NADPH = 2 Fe(II)-[leghemoglobin] + H(+) + NADP(+)


name: Autophosphorylation of PKC-theta (Bos taurus)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Bos taurus)


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Gallus gallus)


name: Luteinizing hormone is a heterodimer (Mus musculus)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: (11Z)-eicosenamide + H2O <=> (11Z)-eicosenoate + NH4(+)


name: INPP5E translocates to the primary cilium (Rattus norvegicus)


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Canis familiaris)


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Mus musculus)


name: Activated MAPKs phosphorylate MAP2K1 (Rattus norvegicus)


name: ent-cassa-12,15-diene + O2 + reduced [NADPH--hemoprotein reductase] = ent-cassa-12,15-dien-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: "[heparan sulfate]-glucosamine 3-sulfotransferase 2"


name: 2-demethylmenaquinol-12 + S-adenosyl-L-methionine => H(+) + menaquinol-12 + S-adenosyl-L-homocysteine


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Mus musculus)


name: TNKS and TNKS2 PARylate PTEN (Gallus gallus)


name: acetyl-CoA + alpha-D-galactosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate


name: branched-chain amino acid transmembrane transporter activity


name: SLC25A44 transports Leu, Ile and Val from cytosol to mitochondrial matrix (Homo sapiens)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Canis familiaris)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: H2O + L-methionine + O2 <=> 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+)


name: Frataxin binds iron (Caenorhabditis elegans)


name: 3-hydroxypropanal + H2O + NAD(+) => 3-hydroxypropanoate + 2 H(+) + NADH


name: cholestanol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-hydroxycholestanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl-[ACP] + AH2 + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine = 6-[(3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl]-2,4-dihydroxy-3-methylbenzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP] + S-adenosyl-L-homocysteine


name: HDACs deacetylate p-STAT3 dimers (Homo sapiens)


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Homo sapiens)


name: SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Mus musculus)


name: dATP + H2O = 2'-deoxyadenosine + H(+) + triphosphate


name: NAD(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH


name: desmethylxanthohumol + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + xanthohumol


name: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H(+) + phosphate


name: STAT3 binds activated MET receptor (Canis familiaris)


name: TBK1 phosphorylates STAT6 at Ser407 (Xenopus tropicalis)


name: an anthocyanidin 3-O-beta-D-glucoside + malonyl-CoA => an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: M protein oligomerization (Homo sapiens)


name: ZNRF3 autoubiquitinates to promote its internalization (Homo sapiens)


name: HMOX1 translocates from the cytosol to the nucleoplasm (Mus musculus)


name: (9Z,12Z)-octadecadienoate + NH4(+) => (9Z,12Z)-octadecadienamide + H2O


name: SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Drosophila melanogaster)


name: POLD,POLE binds deISGylated PCNA after TLS (Xenopus tropicalis)


name: Homodimerization of VEGF proteins (Xenopus tropicalis)


name: 14-3-3epsilon attentuates NADE-related apoptosis (Mus musculus)


name: CDK4 inhibitors bind CDK4 (Drosophila melanogaster)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Canis familiaris)


name: arsenate + 2 Fe(II)-[cytochrome c] + 3 H(+) => arsenite + 2 Fe(III)-[cytochrome c] + H2O


name: H(+) + pre-sodorifen diphosphate + S-adenosyl-L-homocysteine => (2E,6E)-farnesyl diphosphate + S-adenosyl-L-methionine


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Schizosaccharomyces pombe)


name: GGPS1 hexamer transfers IPPP to GPP (Drosophila melanogaster)


name: (9Z)-octadecenoyl-CoA + 2 H2O + NADP(+) => H(+) + NADPH + O2 + octadecanoyl-CoA


name: 3-nitrotoluene + NADH + O2 => 4-methylcatechol + NAD(+) + nitrite


name: H2O + N(6)-(D-psicosyl)-L-lysyl-[protein] => D-allose + L-lysyl-[protein]


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Sus scrofa)


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Canis familiaris)


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Mus musculus)


name: WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)


name: MAPK12 phosphorylates PTPN3 (Caenorhabditis elegans)


name: GPIb-IX-V binds to vWF:Collagen complex (Bos taurus)


name: DMGDH:FAD oxidatively demethylates DMGLY to SARC (Sus scrofa)


name: (E,E)-piperoyl-CoA + AMP + diphosphate => (E,E)-piperate + ATP + CoA


name: RHOA:GTP translocates to the ER membrane (Saccharomyces cerevisiae)


name: PROT mediates L-proline uptake (Homo sapiens)


name: Prolactin receptor is internalized (Sus scrofa)


name: H(+) + prostaglandin E2 + sn-glycero-3-phosphoethanolamine => 2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine + H2O


name: active borate transmembrane transporter activity


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 => (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate


name: Association of  PARVA with TESK1 (Mus musculus)


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)


name: Casein kinase II phosphorylates PTEN (Canis familiaris)


name: 2 cob(I)alamin + H(+) + NAD(+) <=> 2 cob(II)alamin + NADH


name: ZIP6 and ZIP14 mediate zinc influx into cells (Gallus gallus)


name: 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O => (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + H(+)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Mus musculus)


name: botG LC cleaves target cell VAMP1 (Homo sapiens)


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Bos taurus)


name: (2S,3R)-3-geranyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate => (2E)-geranyl diphosphate + L-tryptophyl-[protein]


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Bos taurus)


name: Removal of siRNA passenger strand (Sus scrofa)


name: K63polyUb-RIPK1 is deubiquitinated (Bos taurus)


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Homo sapiens)


name: Formation of P-TEFb complex (Saccharomyces cerevisiae)


name: HuR:mRNA complex translocates from the nucleus to the cytosol (Bos taurus)


name: a 2,3-saturated acyl-CoA + NAD(+) <=> a (2E)-enoyl-CoA + H(+) + NADH


name: O2 + proatranorin I + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin IV


name: CoA + glutarate + H(+) => glutaryl-CoA + H2O


name: aklavinone + H(+) + NADPH + O2 <=> epsilon-rhodomycinone + H2O + NADP(+)


name: D-glucose 6-phosphate + glycerol => D-glucose + sn-glycerol 3-phosphate


name: Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 (Canis familiaris)


name: a fatty acyl-CoA + a sphingoid base <=> an N-acyl-sphingoid base + CoA + H(+)


name: 5-aminopentanal + L-glutamate => 2-oxoglutarate + cadaverine


name: Phosphorylated SHC recruits GRB2:SOS1 (Homo sapiens)


name: N(pros)-phospho-L-histidyl-[protein] + N,N'-diacetylchitobiose(out) <=> diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein]


name: USP12, USP26 deubiquitinate AR (Gallus gallus)


name: ATP + beta-D-fructose 6-phosphate => ADP + beta-D-fructose 1,6-bisphosphate + H(+)


name: PLA2G2A binds bacterial phospholipids (Caenorhabditis elegans)


name: WLS:WNT complex is internalized for maturation into exosomes (Mus musculus)


name: cycloheximide transmembrane transporter activity


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Bos taurus)


name: (S)-indan-1-ol + NAD(+) => H(+) + indan-1-one + NADH


name: Activation of EPACs by cAMP (Schizosaccharomyces pombe)


name: 5alpha,6beta,17alpha-trihydroxywithanolide 27-O-beta-D-glucoside + H(+) + UDP => 5alpha,6beta,17alpha,27-tetrahydroxywithanolide + UDP-alpha-D-glucose


name: NUMB:ITCH binds GLI1 (Xenopus tropicalis)


name: ULK1 phosphorylates Beclin-1 (Schizosaccharomyces pombe)


name: SUMOylation of TOP1 with SUMO1 (Dictyostelium discoideum)


name: CLCN4/5/6 exchange Cl- for H+ (Rattus norvegicus)


name: (25R)-cholest-5-ene-3beta,26-diol + H2O + 2 oxidized [adrenodoxin] => cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: RAC1,RAC2,RHOG activate PI3K (Rattus norvegicus)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + H2O => (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycerol + H(+)


name: IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Xenopus tropicalis)


name: MDH2 dimer dehydrogenates MAL (Schizosaccharomyces pombe)


name: histone H3K72 acetyltransferase activity


name: CHD1L is recruited to GG-NER site (Danio rerio)


name: Binding of STAT1 to p-IFNGR1 (Rattus norvegicus)


name: alpha-secretase cleaves the p75NTR extracellular domain (Gallus gallus)


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Gallus gallus)


name: OSCAR binds collagen and SP-D (Sus scrofa)


name: NADPH + O2 + quinolin-8-ol = 8-hydroxyquinoline N-oxide + H2O + NADP(+)


name: Beta-catenin binds SOX proteins (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate <=> di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate


name: RAC3 GDIs block activation of RAC3 (Xenopus tropicalis)


name: 3-O-(alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + H(+) + UDP


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Rattus norvegicus)


name: CAD hexamer transforms L-Gln to CAP (Rattus norvegicus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NH4(+) => (6S)-5,6,7,8-tetrahydrofolate + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein]


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Rattus norvegicus)


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Bos taurus)


name: RUNX3 binds TEADs and YAP1 (Rattus norvegicus)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Rattus norvegicus)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Rattus norvegicus)


name: 2-methyl-2-(methylamino)propanoate(out) + chloride(out) + 2 Na(+)(out) = 2-methyl-2-(methylamino)propanoate(in) + chloride(in) + 2 Na(+)(in)


name: VANGL2 is phosphorylated in response to WNT5A (Homo sapiens)


name: 2 Na(+)(out) + taurolithocholate 3-sulfate(out) => 2 Na(+)(in) + taurolithocholate 3-sulfate(in)


name: NF1 is degraded by the proteasome (Sus scrofa)


name: PLK1 binds phosphorylated condensin II complex (Caenorhabditis elegans)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Bos taurus)


name: Thrombin-activated PARs:G12/13 (active) dissociate (Bos taurus)


name: arginine + glycine => ornithine + guanidoacetate (Canis familiaris)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Canis familiaris)


name: LRP1 (CD91) binds Hemopexin:heme (Mus musculus)


name: Translocation of YAP1 to the nucleus (Danio rerio)


name: Two FPP molecules dimerize to form presqualene diphosphate (Mus musculus)


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Canis familiaris)


name: acetyl-CoA + benzyl alcohol <=> benzyl acetate + CoA


name: (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + CO2 + CoA


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Mus musculus)


name: 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O => D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate


name: 10-deoxymethymycin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + methymycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: IL1R1 binds IL1R1 inhibitors (Mus musculus)


name: RHOD GAPs stimulate RHOD GTPase activity (Drosophila melanogaster)


name: Growing HA is extruded from the cell by ABCC5 (Xenopus tropicalis)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Xenopus tropicalis)


name: AMPK (complex) phosphorylates ULK1 (complex) (Schizosaccharomyces pombe)


name: Activated FGFR2:p-FRS bind to PPTN11 (Rattus norvegicus)


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Homo sapiens)


name: a phosphate monoester + H2O = an alcohol + phosphate


name: WNT5A binds FZD and ROR receptors (Danio rerio)


name: Formation of MCM2-7 complex (Mus musculus)


name: Expression of Ras-related protein Ral-A (Homo sapiens)


name: benzoate + 2 H(+) + NADPH => benzaldehyde + H2O + NADP(+)


name: misfolded CFTR is degraded by the 26S proteasome (Caenorhabditis elegans)


name: NFE2L2 binds the SRXN1 gene (Homo sapiens)


name: A + H2O + NH4(+) <=> AH2 + H(+) + hydroxylamine


name: 5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity


name: 5S-HETE is oxidised to 5-oxoETE by 5-HEDH (Homo sapiens)


name: EFCAB7:IQCE binds EVC2:EVC (Homo sapiens)


name: SESN1,2,3 bind overoxidized PRDX1 (Danio rerio)


name: H(+) + NADPH + O2 + theophylline => 3-methylxanthine + formaldehyde + H2O + NADP(+)


name: 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+) => L-dopa + O2


name: ERBB2 T733I does not bind tesevatinib (Homo sapiens)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Caenorhabditis elegans)


name: histone H3R2 arginine deiminase activity


name: PDE5A dimer binds PDE5A inhibitors (Xenopus tropicalis)


name: ISGylation of protein phosphatase 1 beta (PP2CB) (Caenorhabditis elegans)


name: [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH


name: 2-oxoglutarate + L-histidine <=> 3-(imidazol-5-yl)pyruvate + L-glutamate


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Bos taurus)


name: Translocation of BMF to mitochondria (Canis familiaris)


name: Association of procollagen type XIII (Mus musculus)


name: Receptor FFAR1 binds free fatty acids (Rattus norvegicus)


name: GBF1 recruits ARF:GDP to the ERGIC (Saccharomyces cerevisiae)


name: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity


name: KPNA2 translocates NBN to the nucleus (Homo sapiens)


name: SORD oxidizes D-sorbitol to Fru (Saccharomyces cerevisiae)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Rattus norvegicus)


name: SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Bos taurus)


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-mannosamine => 3 H(+) + 2 NADH + UDP-N-acetyl-alpha-D-mannosaminouronate


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+) <=> 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH


name: (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2


name: 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> dihydroxyacetone phosphate + L-aspartate 4-semialdehyde


name: ATP + glycine + holo-[peptidyl-carrier protein] = AMP + diphosphate + glycyl-[peptidyl-carrier protein]


name: RAC1 and CDC42 activate PAK1 (Canis familiaris)


name: PP2A-B56 dephosphorylates centromeric cohesin (Rattus norvegicus)


name: 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine => 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine


name: CYP19A1 binds Aromatase inhibitors (Caenorhabditis elegans)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Danio rerio)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Rattus norvegicus)


name: (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD(+) => (2E)-3-(3-hydroxyphenyl)prop-2-enoate + H(+) + NADH + O2


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Gallus gallus)


name: PM20D1 hydrolyzes oleoyl-phe (Saccharomyces cerevisiae)


name: SUMOylation of TOP1 with SUMO1 (Saccharomyces cerevisiae)


name: PRMT5 methylates TP53 (Xenopus tropicalis)


name: ALDH8A1 oxidises 9cRAL to 9cRA (Dictyostelium discoideum)


name: an n-alkanal + NADP(+) = an alk-2-enal + H(+) + NADPH


name: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-hedycaryol + diphosphate


name: 5-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 => (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 3-hydroxy-L-phenylalanine


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Caenorhabditis elegans)


name: ADP + H(+) + N-acetyl-alpha-D-hexosamine 1-phosphate => ATP + N-acetyl-D-hexosamine


name: (R)-normetanephrine + S-adenosyl-L-methionine <=> (R)-metanephrine + H(+) + S-adenosyl-L-homocysteine


name: IL1F10(?-152) binds IL1RAPL1 (Xenopus tropicalis)


name: SRC family kinases phosphorylate ERBB2 (Mus musculus)


name: all-trans-heptaprenyl diphosphate <=> (R)-tetraprenyl-beta-curcumene + diphosphate


name: Degradation of multiubiquitinated Cdh1 (Mus musculus)


name: CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] <=> (indol-3-yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: GAPDH tetramers reduce 1,3BPG to GA3P (Drosophila melanogaster)


name: ADP(out) + dAMP(in) + H(+)(out) <=> ADP(in) + dAMP(out) + H(+)(in)


name: CYTH proteins stimulate ARF1 GTPase activity (Xenopus tropicalis)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycerol + H(+) + phosphoethanolamine


name: SLC6A6-mediated uptake of taurine and beta-alanine (Mus musculus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphate + H(+)


name: Activated FGFR2 binds FRS2 (Drosophila melanogaster)


name: Expression of GLI1 is repressed by GLI3R in the absence of Hh signaling (Homo sapiens)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Drosophila melanogaster)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Caenorhabditis elegans)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Xenopus tropicalis)


name: ESR-associated SRC autophosphorylates (Drosophila melanogaster)


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + octadecanoyl-CoA => 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + CoA


name: Acidification of Tf:TfR1 containing endosome (Rattus norvegicus)


name: 2-oxoglutarate + 3-hydroxy-L-kynurenine <=> H2O + L-glutamate + xanthurenate


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Dictyostelium discoideum)


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein] => a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-lysyl-[protein]


name: HCCS inserts heme into cytochrome c (Saccharomyces cerevisiae)


name: (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + CO2 + CoA


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Rattus norvegicus)


name: CO binds to Cytochrome c oxidase (Canis familiaris)


name: SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids (Gallus gallus)


name: an archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate => an archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy- beta-D-glucuronosyl)-N-acetyl- alpha-D-glucosaminyl phosphate + H(+) + UDP


name: 2 2-iminio-3-(indol-3-yl)propanoate + H2O2 = 2 H2O + indole-3-pyruvate imine dimer


name: [pyruvate, water dikinase] + ADP <=> [pyruvate, water dikinase]-phosphate + AMP + H(+)


name: H(+) + NADPH + O2 + resorcinol => benzene-1,2,4-triol + H2O + NADP(+)


name: D-iditol + NAD(+) => H(+) + keto-D-sorbose + NADH


name: 3 H(+) + 3 malonyl-CoA <=> 1,3,5-trihydroxybenzene + 3 CO2 + 3 CoA


name: 19-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2


name: PPP1CC dephosphorylates PLK1 (Gallus gallus)


name: Formation of the MLL4 complex (Homo sapiens)


name: phthalate 4,5-cis-dihydrodiol dehydrogenase activity


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Saccharomyces cerevisiae)


name: H2O + N-methylputrescine + O2 = 4-methylaminobutanal + H2O2 + NH4(+)


name: 3-methylcatechol + O2 = 2-hydroxy-6-oxo-2,4-heptadienoate + H(+)


name: RHOA GEFs activate RHOA (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 => (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate


name: SRPK1 phosphorylates PRM2 in PRM2:dsDNA (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of SHC1 by ERBB4 homodimers (Drosophila melanogaster)


name: gamma-L-glutamyl-hercynylcysteine S-oxide + H2O = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide


name: "gamma-glutamyl hercynylcysteine S-oxide hydrolase"


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate <=> D-glyceraldehyde 3-phosphate + pyruvate


name: H2O + luteolin 4'-O-beta-D-glucoside => beta-D-glucose + luteolin


name: 2 a quinone + H(+) + NADH => 2 a 1,4-benzosemiquinone + NAD(+)


name: Hyperphosphorylated IRAK1 associates with TRAF6 (Homo sapiens)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Mus musculus)


name: (E)-non-2-enoate + 2 H(+) + NADH => (E)-non-2-enal + H2O + NAD(+)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Plasmodium falciparum)


name: Release of E3 from polyubiquitinated substrate (Schizosaccharomyces pombe)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Gallus gallus)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Mus musculus)


name: CO2 + H(+) + hexanal + succinate + sulfate => 2-oxoglutarate + hexyl sulfate + O2


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Homo sapiens)


name: salicylic acid glucosyltransferase (glucoside-forming) activity


name: geranylgeranyl diphosphate + H2O = (S)-(+)-nephthenol + diphosphate


name: 7alpha-hydroxy-3,12-dioxo-5beta-cholanate + NADP(+) <=> dehydrocholate + H(+) + NADPH


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Mus musculus)


name: (R)-propane-1,2-diol + NAD(+) => (R)-lactaldehyde + H(+) + NADH


name: Endosomal TLRs pass through the Golgi (Xenopus tropicalis)


name: all-trans-antheraxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> all-trans-violaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Gallus gallus)


name: uridine(2819) in 21S rRNA <=> pseudouridine(2819) in 21S rRNA


name: cyclohexanol + NAD(+) => cyclohexanone + H(+) + NADH


name: Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Sus scrofa)


name: NNMT transfers CH3 from AdoMet to PY (Homo sapiens)


name: a 1,2-saturated fatty acid + O2 <=> a (2R)-2-hydroperoxy fatty acid


name: (R)-carnitine + 2-methylpropanoyl-CoA <=> CoA + O-isobutanoyl-(R)-carnitine


name: Type I Na+-coupled phosphate co-transport (Mus musculus)


name: 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 24 H(+) + 8 malonyl-CoA + 16 NADPH <=> 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+)


name: Caspase-mediated cleavage of E-Cadherin (Drosophila melanogaster)


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Xenopus tropicalis)


name: [mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + AH2 + S-adenosyl-L-methionine = 5'-deoxyadenosine + [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + A + H(+) + L-methionine


name: ATP7A transports cytosolic Cu2+ to extracellular region (Xenopus tropicalis)


name: a ganglioside GT1a + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1b + CMP + H(+)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Gallus gallus)


name: p-VAV family:PIP3 binds RAC1:GDP (Rattus norvegicus)


name: Activated FGFR3 phosphorylates FRS3 (Homo sapiens)


name: (4R)-hydroxysphinganine(in) + ATP + H2O <=> (4R)-hydroxysphinganine(out) + ADP + H(+) + phosphate


name: (2R,4S)-ketoconazole(out) + ADP + H(+) + phosphate => (2R,4S)-ketoconazole(in) + ATP + H2O


name: 16alpha,17beta-estriol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate <=> 16alpha,17beta-estriol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)