name: Phosphorylation of IKK-beta by TAK1 (Rattus norvegicus)


name: 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O => (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+)


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Xenopus tropicalis)


name: Interaction of PECAM-1 and SHP-2 (Gallus gallus)


name: MRN complex binds CDK2 and RBBP8 (Homo sapiens)


name: VAV2 is a GEF for Rho/Rac family kinases (Rattus norvegicus)


name: acetyl phosphate + L-lysine <=> H(+) + N(6)-acetyl-L-lysine + phosphate


name: (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E,19Z)-docosahexaenoate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 O2


name: IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Rattus norvegicus)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Homo sapiens)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 = (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate


name: (1R,4S)-menthone + H(+) + NADPH + O2 => (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+)


name: PEX19:class I PMP binds PEX3 (Sus scrofa)


name: H2O + presqualene phosphate => phosphate + presqualene alcohol


name: sulfosungeidine F => H(+) + sulfate + sungeidine A


name: (13E)-labda-7,13-dien-15-ol + diphosphate => (13E)-labda-7,13-dien-15-yl diphosphate + H2O


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate <=> 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: L-threonate + NAD(+) = 2-dehydro-L-erythronate + H(+) + NADH


name: Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C-> Beta-tubulin:GDP :alpha-tubulin:GTP heterodimer +Cofactor E+ Cofactor D+ Cofactor C+ Pi (Homo sapiens)


name: 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O => 5alpha-cholestane-3beta,5,6beta-triol


name: 2,6-dihydroxypyridine + H(+) + NADH + O2 = 2,3,6-trihydroxypyridine + H2O + NAD(+)


name: 5-hydroxymethyl-dUMP in DNA + ATP = 5-phosphomethyl-dUMP in DNA + ADP + H(+)


name: TCF:Beta-catenin binds SOX proteins (Bos taurus)


name: cysteamine S-phosphate + H2O <=> cysteamine + phosphate


name: agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O => 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate


name: CUL3:RBX1 ubiquitinates KEAP1 (Rattus norvegicus)


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Mus musculus)


name: HTR3A antagonists bind HTR3A pentamer (Canis familiaris)


name: HSD11B2 dehydrogenates PREDL to PREDN (Sus scrofa)


name: PXLP-K56-SRR dimer deaminates L-Ser (Rattus norvegicus)


name: 2'-deamino-2'-hydroxyparomamine + H(+) + UDP => 2-deoxystreptamine + UDP-alpha-D-glucose


name: (15S)-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate => (8Z,11Z,14Z)-eicosatrienoate + O2


name: Beta-tubulin:GTP + Cofactor D ->  Beta-tubulin:GTP: Cofactor D (Homo sapiens)


name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 (Sus scrofa)


name: Activation of Rho by LARG and PDZ-RhoGEF (Danio rerio)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)


name: beta-alanine + L-arginine <=> 3-guanidinopropanoate + L-ornithine


name: Internalization of gap junction plaques (Bos taurus)


name: alpha-D-glucose 1-phosphate + alpha-D-mannose derivative + H(+) => 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H2O


name: 3 H(+) + hexanoyl-CoA + 3 malonyl-CoA <=> 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: H(+) + H2O + S-methyl-5'-thioadenosine <=> NH4(+) + S-methyl-5'-thioinosine


name: D-maltotetraono-1,5-lactone + H2O = D-maltotetraonate + H(+)


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Dictyostelium discoideum)


name: LONP1 degrades mitochondrial inner membrane proteins (Gallus gallus)


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Mus musculus)


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline <=> 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Rattus norvegicus)


name: 1,7-dimethylxanthine + H(+) + NADPH + O2 = 7-methylxanthine + formaldehyde + H2O + NADP(+)


name: Phosphorylation of Platelet Sec-1 (Bos taurus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Saccharomyces cerevisiae)


name: ABC-type teichoic acid transporter activity


name: CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 (Homo sapiens)


name: NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Schizosaccharomyces pombe)


name: 2-demethylmenaquinol-6 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-hexaprenyl diphosphate + H(+)


name: Aquaporins passively transport glycerol out of cells (Homo sapiens)


name: 3,4,5-trihydroxybenzoate(out) + H(+)(out) <=> 3,4,5-trihydroxybenzoate(in) + H(+)(in)


name: (6S)-5,6,7,8-tetrahydrofolate + vanillate = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 3,4-dihydroxybenzoate


name: CYP4F12 18-hydroxylates ARA (Xenopus tropicalis)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Dictyostelium discoideum)


name: chloride(out) + D-tryptophan(out) + 2 Na(+)(out) = chloride(in) + D-tryptophan(in) + 2 Na(+)(in)


name: Degradation of ubiquitinated beta catenin by the proteasome (Rattus norvegicus)


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Caenorhabditis elegans)


name: H2O + prostaglandin E2 1-glyceryl ester => glycerol + H(+) + prostaglandin E2


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)


name: acetyl-CoA + GDP-alpha-D-perosamine => CoA + GDP-N-acetyl-alpha-D-perosamine + H(+)


name: (3R)-citramalyl-CoA => acetyl-CoA + pyruvate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Homodimerization  of DFF40 (Mus musculus)


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Canis familiaris)


name: TDP1 and TDP2 process unligatable DSB ends (Homo sapiens)


name: RHOA binds effectors at the plasma membrane (Homo sapiens)


name: 3-oxoisoapionate 4-phosphate + H(+) = CO2 + L-erythrulose 1-phosphate


name: ASPG hydrolyses L-Asn to L-Asp (Mus musculus)


name: Activated FGFR2 phosphorylates FRS3 (Danio rerio)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Caenorhabditis elegans)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Caenorhabditis elegans)


name: (R)-2-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Bos taurus)


name: GBA2 hydrolyzes GlcCer (plasma membrane) (Drosophila melanogaster)


name: (2E,6E)-farnesoate + S-adenosyl-L-methionine = methyl (2E,6E)-farnesoate + S-adenosyl-L-homocysteine


name: L-aspartate(in) + sulfate(out) => L-aspartate(out) + sulfate(in)


name: 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate](n) <=> 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)


name: H(+) + sitosteryl 3-beta-D-glucoside + UDP => sitosterol + UDP-alpha-D-glucose


name: myo-inositol + O2 <=> D-glucuronate + H(+) + H2O


name: DLST transfers succinyl to CoA (Dictyostelium discoideum)


name: M6PR transports activated ARSA to the lysosome (Rattus norvegicus)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Xenopus tropicalis)


name: PDK1 phosphorylates PKC (Saccharomyces cerevisiae)


name: (20S)-ginsenoside Rh1 + H(+) + UDP => (20S)-protopanaxatriol + UDP-alpha-D-glucose


name: (2S)-2-amino-2'-deoxyadenylo-succinate <=> dZMP + fumarate


name: SUMOylation of NOP58 with SUMO2 (Mus musculus)


name: CYP21A2 21-hydroxylates PROG (Homo sapiens)


name: GSDME (1-270) binds PIPs (Gallus gallus)


name: 3beta-hydroxy-5alpha-androstan-17-one + O2 + reduced [NADPH--hemoprotein reductase] = 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+) => H2O + thiamine


name: RHOT1 binds effectors at the mitochondrial outer membrane (Mus musculus)


name: UDP-alpha-D-glucose + validoxylamine A <=> H(+) + UDP + validamycin A


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Gallus gallus)


name: FDPS dimer transfers IPPP to DMAPP (Schizosaccharomyces pombe)


name: Formation of P-TEFb complex (Danio rerio)


name: chloride(out) + L-lysine(out) + 2 Na(+)(out) <=> chloride(in) + L-lysine(in) + 2 Na(+)(in)


name: Autophosphorylation of PDGF beta receptors (Mus musculus)


name: 19-hydroxy-11-deoxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 19-oxo-11-deoxycorticosterone + 2 H2O + 2 oxidized [adrenodoxin]


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + H(+)(out) <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: STAT5 tyrosine phosphorylation (Homo sapiens)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Xenopus tropicalis)


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Canis familiaris)


name: Phosphorylation of RPA2 by CDC2 kinase (Gallus gallus)


name: p-S407,Y641-STAT6 is dimerized (Bos taurus)


name: USP13 deubiquitinates BECN1,USP10 (Gallus gallus)


name: a 2,3-saturated acyl-[ACP] + NADP(+) => a (2E)-enoyl-[ACP] + H(+) + NADPH


name: deamido-NAD(+)(in) + NAD(+)(out) <=> deamido-NAD(+)(out) + NAD(+)(in)


name: L-alanine(out) + L-glutamine(in) + Na(+)(out) = L-alanine(in) + L-glutamine(out) + Na(+)(in)


name: a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GM1 (d18:1(4E)) + H(+) + UDP


name: IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 (Bos taurus)


name: eIF2 activation (Saccharomyces cerevisiae)


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe (Danio rerio)


name: PIAS1,3 SUMOylate ESR1 with SUMO1 (Homo sapiens)


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)


name: N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Drosophila melanogaster)


name: Transfer of ISG15 from E1 to E2 (UBCH8) (Rattus norvegicus)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Bos taurus)


name: Aquaporin-3 passively transports water out of cell (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + 2 H2O <=> 2 a carboxylate + 2 H(+) + sn-glycero-3-phospho-1D-myo-inositol


name: gamma-hexachlorocyclohexane => (3R,4S,5S,6R)-pentachlorocyclohexene + chloride + H(+)


name: a fatty acyl-CoA + a long chain fatty alcohol => a wax ester + CoA


name: CYCS:APAF1 binds procaspase-9 (Xenopus tropicalis)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Dictyostelium discoideum)


name: NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH


name: barbiturate + H2O = 3-oxo-3-ureidopropanoate


name: H2O2 + NADP(+) => 1,2-dihydro-beta-NADP + H(+) + O2


name: 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Gallus gallus)


name: (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + H2O <=> (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + phosphate


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: G protein-coupled acetylcholine receptor activity


name: (S)-2-benzylsuccinate + succinyl-CoA <=> (S)-2-benzylsuccinyl-CoA + succinate


name: carbamoyl adenylate + kanamycin A <=> 6''-O-carbamoylkanamycin A + AMP + H(+)


name: benzoyl-CoA + hexan-2-ol => CoA + hexan-2-yl benzoate


name: SLCO2B1 has a narrow substrate specificity (Xenopus tropicalis)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 6beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Tenascins C, R, (X, N) bind lecticans (Bos taurus)


name: LPS binding to CD14 co-receptor (Gallus gallus)


name: L-histidine + S-adenosyl-L-methionine => H(+) + N(alpha)-methyl-L-histidine + S-adenosyl-L-homocysteine


name: [protein]-C-terminal Gly-Gly-AMP + diphosphate => [protein]-C-terminal Gly-Gly + ATP + H(+)


name: Fe(III)-[cytochrome c](out) => Fe(III)-[cytochrome c](in)


name: tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex (Canis familiaris)


name: RNA polymerase II CTD heptapeptide repeat phosphatase activity


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Rattus norvegicus)


name: AMP(out) + UDP-alpha-D-galactose(in) = AMP(in) + UDP-alpha-D-galactose(out)


name: Binding of AP1 transcriptional activator complexes to CCND1 promoter (Drosophila melanogaster)


name: L-aspartate + NH4(+) => H2O + L-asparagine


name: N-myristoylation of eNOS (Plasmodium falciparum)


name: NAD(+) + S-(2-aminoethyl)-L-cysteine <=> (4S)-5,6-dihydro-4H-1,3-thiazine-4-carboxylate + 2 H(+) + NADH + NH4(+)


name: H2O + L-arabinono-1,4-lactone = H(+) + L-arabinonate


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADPH


name: formate + H(+) + L-kynurenine => H2O + N-formyl-L-kynurenine


name: 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+) => 2-phenylethanol + 2 Fe(III)-[cytochrome c]


name: alpha,alpha-trehalose 6-phosphate + H2O <=> alpha,alpha-trehalose + phosphate


name: MsrA/B reduces peptide-methionine S/R-sulfoxides (Homo sapiens)


name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol (Mus musculus)


name: ADP + beta-D-fructose 2,6-bisphosphate + H(+) => ATP + beta-D-fructose 6-phosphate


name: DCN (decorin) degradation by MMP14 (Danio rerio)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Caenorhabditis elegans)


name: butanoyl-CoA + NADP(+) => (2E)-butenoyl-CoA + H(+) + NADPH


name: 1-O-alkyl-sn-glycero-3-phosphate + acetyl-CoA <=> 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA


name: CTLH E3 ligase ubiquitinates LDHA (Xenopus tropicalis)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Canis familiaris)


name: 3-sulfanylpropanoate + O2 = 3-sulfinopropanoate + H(+)


name: 4-guanidinobutanal + H2O2 + NH4(+) => agmatine + H2O + O2


name: TNFSF11 binds TNFRSF11A, B (Gallus gallus)


name: H2O + L-isoleucine + O2 => (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: Exocytosis of ficolin-rich granule membrane proteins (Dictyostelium discoideum)


name: an anthocyanidin 3-O-beta-D-galactoside + UDP => an anthocyanidin + UDP-alpha-D-galactose


name: isoheptadecanoyl-coA + NADP(+) => (2E)-15-methylhexadecenoyl-CoA + H(+) + NADPH


name: nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Canis familiaris)


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Plasmodium falciparum)


name: A + cholest-4-en-3-one + H2O => 25-hydroxycholest-4-en-3-one + AH2


name: Myoglobin:oxygen dissociates (Bos taurus)


name: NOX2 generates superoxide from oxygen (Rattus norvegicus)


name: allantoate + H(+) => (S)-allantoin + H2O


name: 2 AH2 + all-trans-lycopene => 2 A + all-trans-zeta-carotene


name: RAB:GTP recruits GBF1 to the Golgi membrane (Homo sapiens)


name: rebaudioside B + UDP-alpha-D-glucose = rebaudioside A + UDP


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Gallus gallus)


name: HLCS biotinylates ACACA:Mn2+ (Canis familiaris)


name: decan-1-ol + hexadecanoyl-CoA => CoA + decanyl hexadecanoate


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Canis familiaris)


name: Aggrecan binds Hyaluronan and HAPLN1 (Canis familiaris)


name: Syndecans 2, (4) bind TGFB1 (Drosophila melanogaster)


name: threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate (Homo sapiens)


name: ATPase-coupled L-glutamate tranmembrane transporter activity


name: DNA ligase I ligates single stranded nick in double stranded DNA (Dictyostelium discoideum)


name: acrylate:acyl-coA CoA transferase activity


name: Interaction of DAP12 and KIR2DS2 (Sus scrofa)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Caenorhabditis elegans)


name: AMP(out) + FMN(in) => AMP(in) + FMN(out)


name: p-PKR dimer phosphorylates CDK1 (Homo sapiens)


name: GLI proteins bind SUFU (Drosophila melanogaster)


name: SALM1 binds NMDA receptor (Caenorhabditis elegans)


name: H(+) + NADH + NH4(+) + pentan-3-one => 3-aminopentane + H2O + NAD(+)


name: NFE2L2-dependent PRDX1 gene expression (Homo sapiens)


name: adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine


name: H2O + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine => H(+) + N-hexadecanoylethanolamine + sn-glycerol 3-phosphate


name: AMP + an aromatic aldehyde + diphosphate + NADP(+) => an aromatic carboxylate + ATP + H(+) + NADPH


name: SLC50A1 transports Glc from cytosol to extracellular region (Sus scrofa)


name: 2 Fe(III)-[cytochrome b1] + formate = CO2 + 2 Fe(II)-[cytochrome b1] + H(+)


name: H2O + presqualene diphosphate = diphosphate + hydroxysqualene


name: Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Homo sapiens)


name: a D-hexose 6-phosphate + ADP + H(+) => a D-hexose + ATP


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Bos taurus)


name: 5-guanidino-2-oxopentanoate + H(+) <=> 4-guanidinobutanal + CO2


name: C2CD3 binds the mother centriole (Mus musculus)


name: DENND4s exchange GTP for GDP on RAB10 (Caenorhabditis elegans)


name: CoA + H(+) + taurochenodeoxycholate => chenodeoxycholoyl-CoA + taurine


name: phosphoenolpyruvate + ADP => pyruvate + ATP (Gallus gallus)


name: IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Mus musculus)


name: CBL binds and ubiquitinates phosphorylated Sprouty (Drosophila melanogaster)


name: Fall Back to Closed Pre-initiation Complex (Saccharomyces cerevisiae)


name: 1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = 1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Rattus norvegicus)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)


name: XDH dehydrogenates xanthine to form urate (Caenorhabditis elegans)


name: Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)


name: ADP + H(+) + sulfate => adenosine 5'-phosphosulfate + phosphate


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADH => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+)


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Canis familiaris)


name: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> H(+) + menaquinol-8 + S-adenosyl-L-homocysteine


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Bos taurus)


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Mus musculus)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-R + CMP + H(+) => an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> a 1-acyl-sn-glycero-3-phosphocholine + a cardiolipin


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Canis familiaris)


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Homo sapiens)


name: glutamate-cysteine ligase catalytic subunit binding


name: folic acid transmembrane transporter activity


name: FMNH2 + NADP(+) <=> FMN + 2 H(+) + NADPH


name: O2 + oleanolate + reduced [NADPH--hemoprotein reductase] = cochalate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Bos taurus)


name: an N-acetyl-alpha-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl derivative + H(+) + UDP


name: PKA phosphorylates DARPP-32 on Thr34 (Mus musculus)


name: GABRR pentamers:GABA transports extracellular Cl- to cytosol (Homo sapiens)


name: Transport of L-Glutamine (cytosol) to mitochondrial matrix (Homo sapiens)


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Drosophila melanogaster)


name: 5-oxo-(6E,8Z)-octadecadienoate + H(+) + 2 H2O + oxidized [NADH--hemoprotein reductase] => (5S)-hydroxy-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase]


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Danio rerio)


name: 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one <=> (E)-caffeoylpyruvate + CO2 + hnu


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Sus scrofa)


name: (Z)-24-ethylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 <=> 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = n acetate + chitosan


name: 2-acyl LPI is acylated to PI by MBOAT7 (Bos taurus)


name: glycyl-L-glutamine + H2O => glycine + L-glutamine


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Gallus gallus)


name: (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + CO2 + CoA


name: formaldehyde + H2O + NAD(+) <=> formate + 2 H(+) + NADH


name: an L-alpha-amino acid + H2O + NAD(+) = a 2-oxocarboxylate + H(+) + NADH + NH4(+)


name: GPIb:IX:V binds to VWF multimer:collagen (Bos taurus)


name: Plk1-mediated phosphorylation of Nlp (Canis familiaris)


name: H(+) + indole + NADH + O2 <=> H2O + indoxyl + NAD(+)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Canis familiaris)


name: L-alaninol + L-glutamate => gamma-L-glutamyl-L-alaninol + H2O


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Drosophila melanogaster)


name: FMO3:FAD N-oxidises TMA to TMAO (Bos taurus)


name: O2 + prostaglandin I2 + reduced [NADPH--hemoprotein reductase] => 19-hydroxy-prostaglandin I2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Xenopus tropicalis)


name: D-sorbitol 6-phosphate + NADP(+) <=> aldehydo-D-glucose 6-phosphate + H(+) + NADPH


name: sn-glycerol 3-phosphate(in) <=> sn-glycerol 3-phosphate(out)


name: CES3 hydrolyses CHEST to CHOL and LCFA(-) (Danio rerio)


name: 2-succinylbenzoyl-CoA + AMP + diphosphate => 2-succinylbenzoate + ATP + CoA


name: 5-(carboxymethyl)uridine(34) in tRNA + S-adenosyl-L-methionine => 5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA + S-adenosyl-L-homocysteine


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Saccharomyces cerevisiae)


name: Tyrosine kinase Hopscotch (HOP) binds to the transmembrane cytokine receptor Domeless (DOME) to form the HOP:DOME complex (Drosophila melanogaster)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(34-hydroxytetratriacontadienoyl)-sphing-4-enine => a diacylglycerol + an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontadienoyl)-sphing-4-enine


name: biotinyl-5'-AMP + L-lysyl-[protein] <=> AMP + 2 H(+) + N(6)-biotinyl-L-lysyl-[protein]


name: 7 (S)-methylmalonyl-CoA + 21 H(+) + hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 14 NADPH => C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 7 CO2 + 7 CoA + 7 H2O + 14 NADP(+)


name: (2R,3S)-piscidate + (E)-4-coumaroyl-CoA => cimicifugate K + CoA


name: Ubiquitination of stimulated EGFR (CBL) (Canis familiaris)


name: ATP + H(+) + L-alanine = diphosphate + L-alanyl-5'-AMP


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Plasmodium falciparum)


name: ABCB4 transports PC from plasma membrane to extracellular region (Plasmodium falciparum)


name: a ganglioside GA1 + H(+) + UDP => a ganglioside GA2 + UDP-alpha-D-galactose


name: (S)-eriodictyol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase]


name: IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)


name: ALDH7A1 oxidises BETALD to BET (Bos taurus)


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Dictyostelium discoideum)


name: Formation of the SET1B complex (Mus musculus)


name: HSD17B13 binds lipid droplets (Rattus norvegicus)


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Bos taurus)


name: Transfer of NEDD8 to AcM-UBE2F (Saccharomyces cerevisiae)


name: 2-oxoglutarate + L-histidyl-[protein] + O2 <=> (3S)-3-hydroxy-L-histidyl-[protein] + CO2 + succinate


name: SUMOylation of Histone H4 with SUMO3 (Mus musculus)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Mus musculus)


name: Activation of Ca2+ activated Potassium channels with small conductance (Drosophila melanogaster)


name: PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Canis familiaris)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + diphosphate <=> 5-amino-4-imidazolecarboxyamide + 5-phospho-alpha-D-ribose 1-diphosphate


name: ent-7alpha-hydroxykaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] => gibberellin A12 aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2 => dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+)


name: Cdc6 protein is phosphorylated by CDK (Drosophila melanogaster)


name: formate + succinyl-CoA => formyl-CoA + succinate


name: UBQLNs bind UIM-containing adaptor proteins (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out)


name: PREX2 binds PTEN and inhibits it (Rattus norvegicus)


name: 3 a ubiquinone(in) + 2 H2O(out) + NH4(+)(out) => 3 a ubiquinol(in) + 2 H(+)(out) + nitrite(out)


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Homo sapiens)


name: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate <=> 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate


name: Activated ATM phosphorylates DCLRE1C (Sus scrofa)


name: The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)


name: Gq activation by TP receptor (Xenopus tropicalis)


name: 6-hydroxypseudooxynicotine + A + H2O = 2,6-dihydroxypseudooxynicotine + AH2


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Dictyostelium discoideum)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Xenopus tropicalis)


name: RHOD translocates to the Golgi membrane (Danio rerio)


name: Grb7 binds to the active PDGF receptor (Canis familiaris)


name: SALMs1-3 bind each other in cis interactions (Rattus norvegicus)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Gallus gallus)


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Mus musculus)


name: Role of myosins in phagosome formation (Canis familiaris)


name: 3 2,3-dihydroxybenzoate + 6 ATP + 3 glycine + 3 L-threonine => 6 AMP + corynebactin + 6 diphosphate + 3 H(+) + 3 H2O


name: Caspase mediated cleavage of BAP31 (Canis familiaris)


name: NKG2D homodimer interacting with ligands (Rattus norvegicus)


name: GGT dimers hydrolyse GSH (Rattus norvegicus)


name: SUMOylation of HIPK2 with SUMO1 (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + trichodiene


name: TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine (Homo sapiens)


name: succinate(out) + urate(in) => succinate(in) + urate(out)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + a 1-acyl-sn-glycero-3-phosphoethanolamine + H(+) => 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O


name: D-glucurono-6,2-lactone + H2O <=> D-glucuronate + H(+)


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-galctosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: tri-trans,hepta-cis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine => N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UMP


name: N,N',N''-triacetylchitotriose + O2 => H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone


name: ATP + beta-nicotinamide D-ribonucleotide + H(+) = diphosphate + NAD(+)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Homo sapiens)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Sus scrofa)


name: 3-methylquinoline + A + H2O <=> 3-methylquinolin-2(1H)-one + AH2


name: RUNX1:CBFB binds FOXP3 gene (Homo sapiens)


name: Proteasome proteolyzes ub-HIF-alpha (Caenorhabditis elegans)


name: (E)-caffeate + S-adenosyl-L-methionine => (E)-ferulate + H(+) + S-adenosyl-L-homocysteine


name: GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone <=> 2-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FAD + H(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + FADH2


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + NADP(+) <=> 1-(9Z)-octadecenoylglycerone 3-phosphate + H(+) + NADPH


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: H2O + N-terminal N(alpha)-acetyl-L-cysteinyl-L-aspartyl-[protein] <=> N-acetyl-L-cysteine + N-terminal L-aspartyl-[protein]


name: SLC25A18,22 import L-Glu, H+ (Danio rerio)


name: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate


name: Binding of cAMP to HCN channels (Xenopus tropicalis)


name: 3-epihydroxy-2'-deoxymugineate + CO2 + H(+) + succinate => 2'-deoxymugineate + 2-oxoglutarate + O2


name: AP-1 transcription factor binds IL1A promoter (Homo sapiens)


name: Dephosphorylation of PAG by SHP2 (Mus musculus)


name: MDM2 ubiquitinates JMY (Xenopus tropicalis)


name: acetyl-CoA + H2O <=> acetate + CoA + H(+)


name: apelin-13 + H2O => apelin-12 + L-phenylalanine


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Caenorhabditis elegans)


name: diphosphate + N(6)-(dimethylallyl)adenosine 5'-triphosphate => ATP + dimethylallyl diphosphate


name: 3-hydroxyphenylacetate + H(+) + NADH + O2 <=> H2O + homogentisate + NAD(+)


name: JUN kinase kinase kinase kinase activity


name: RHOF GAPs stimulate RHOF GTPase activity (Saccharomyces cerevisiae)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: p-STAT1 binds p-STAT3 (Rattus norvegicus)


name: Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Danio rerio)


name: H(+) + precorrin-3A + S-adenosyl-L-homocysteine => precorrin-2 + S-adenosyl-L-methionine


name: Collagen type XVIII endostatin release (Bos taurus)


name: 2'-phospho-[ligated tRNA] + NAD(+) => ADP-alpha-D-ribose 1'',2''-cyclic phosphate + mature tRNA + nicotinamide


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Homo sapiens)


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) <=> 4,5-dihydroxyphthalate + H(+) + NADH


name: DNA polymerase epsilon binds at the origin (Canis familiaris)


name: [(1->3)-alpha-D-glucosyl](n) + phosphate <=> [(1->3)-alpha-D-glucosyl](n-1) + beta-D-glucose 1-phosphate


name: Oxidation of cholesterol to 22beta-hydroxycholesterol (Xenopus tropicalis)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Caenorhabditis elegans)


name: 2 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol = all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol


name: NAD(+) + trans-4-hydroxycyclohexane-1-carboxylate <=> 4-oxocyclohexane-1-carboxylate + H(+) + NADH


name: GDIs bind RHOH (Drosophila melanogaster)


name: dopamine + L-glutaminyl-[protein] <=> 5-dopaminyl-L-glutamyl-[protein] + NH4(+)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Bos taurus)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Dictyostelium discoideum)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+) => a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphate + H2O


name: 2-furoate + 2 H(+) + NADH => furfural + H2O + NAD(+)


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Saccharomyces cerevisiae)


name: H(+)(in) + L-galactonate(in) => H(+)(out) + L-galactonate(out)


name: ATP + dimethylallyl diphosphate <=> diphosphate + N(6)-(dimethylallyl)adenosine 5'-triphosphate


name: N-hydroxy-L-valine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-valine + oxidized [NADPH--hemoprotein reductase]


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Drosophila melanogaster)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Caenorhabditis elegans)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Bos taurus)


name: PHGDH tetramer dehydrogenates 3PG (Sus scrofa)


name: 12alpha-hydroxy-3-oxochola-4-en-24-oate + NAD(+) <=> 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(+) + NADH


name: TRAF6 binding leads to IRAK1:TRAF6 release (Rattus norvegicus)


name: ABCC3 transports bile salts from cytosol to extracellular region (Canis familiaris)


name: Adhesion of integrin alphaIIbbeta3 to fibrin network (Rattus norvegicus)


name: inorganic diphosphate phosphatase activity


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Canis familiaris)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Danio rerio)


name: ASPG hydrolyses L-Asn to L-Asp (Xenopus tropicalis)


name: Dentin phosphoprotein binds integrin alphaVbeta1 (Canis familiaris)


name: RNF8 and RNF168 ubiquitinate KDM4A,B (Sus scrofa)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Xenopus tropicalis)


name: PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) (Homo sapiens)


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Caenorhabditis elegans)


name: Syndecans 1, 2 & 4 bind VTN (Danio rerio)


name: STAT3 is phosphorylated downstream of active ALK (Canis familiaris)


name: 2-carboxy-5-(dihydroxymethyl)furan + O2 => 2,5-dicarboxyfuran + H(+) + H2O2


name: CX3 complex binds D-loop structures (Homo sapiens)


name: ADP + folate(out) + H(+) + phosphate => ATP + folate(in) + H2O


name: L-phenylalanine(out) + L-valine(in) => L-phenylalanine(in) + L-valine(out)


name: Casein kinase II phosphorylates PTEN (Bos taurus)


name: PHGDH tetramer dehydrogenates 3PG (Caenorhabditis elegans)


name: 2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine <=> 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate


name: ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine => ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine


name: (-)-4'-desmethyl-deoxypodophyllotoxin + O2 + reduced [NADPH--hemoprotein reductase] = 4'-demethylepipodophyllotoxin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,3-bisphosphoglycerate + ADP <=> 3-phosphoglycerate + ATP (Gallus gallus)


name: RAC1:GTP binds NOX1 complex (Rattus norvegicus)


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Canis familiaris)


name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Sus scrofa)


name: DDX41 ubiquitination by TRIM21 (Canis familiaris)


name: Activated TLR5/TLR15 homodimer recruits MyD88 adaptor (Gallus gallus)


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Xenopus tropicalis)


name: a dipeptide(out) + H(+)(out) <=> a dipeptide(in) + H(+)(in)


name: (R)-carnitine + 2-methylbutanoyl-CoA <=> CoA + O-2-methylbutanoyl-(R)-carnitine


name: (E)-coniferol + A <=> (E)-coniferaldehyde + AH2


name: CO2 + diphosphate + nicotinate beta-D-ribonucleotide <=> 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = 8-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Drosophila melanogaster)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> 7-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Homo sapiens)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Xenopus tropicalis)


name: Phosphorylated SHC recruits GRB2:SOS1 (Rattus norvegicus)


name: 2,3-dihydroxybenzoyl-[ACP] + AMP + H(+) => 2,3-dihydroxybenzoyl-5'-AMP + holo-[ACP]


name: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 <=> 4-chloro-L-lysine + CO2 + H2O + succinate


name: [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity


name: aspulvinone H + 2 diphosphate => aspulvinone E + 2 dimethylallyl diphosphate


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol => a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol


name: H(+) + NADH + ubiquinone-10 => NAD(+) + ubiquinol-10


name: Nephrin interacts with Podocin (Rattus norvegicus)


name: H(+) + malonyl-CoA + triacontanoyl-CoA => 3-oxo-dotriacontanoyl-CoA + CO2 + CoA


name: L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + UDP


name: 21-hydroxyprogesterone + H(+) + NADPH = 5beta-dihydrodeoxycorticosterone + NADP(+)


name: P4HB forms mixed disulphides with Hh precursors (Homo sapiens)


name: VAV2 is a GEF for Rho/Rac family kinases (Gallus gallus)


name: diphosphate + terpentetriene => terpentedienyl diphosphate


name: Inactivation of APC/C via CDC20 sequestration (Rattus norvegicus)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)


name: (11R)-19-oxocarlactone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (11R)-19-hydroxycarlactone + O2 + reduced [NADPH--hemoprotein reductase]


name: an aldopyranose + NADP(+) = aldono-1,5-lactone + H(+) + NADPH


name: H(+) + heptan-2-one + NADPH + O2 => H2O + NADP(+) + pentyl acetate


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Mus musculus)


name: Formation of C-strand Okazaki fragments (Homo sapiens)


name: H(+) + NADPH + tropinone => NADP(+) + pseudotropine


name: (indol-3-yl)butanoate + UDP-alpha-D-glucose => 4-(indol-3-yl)butanoyl-beta-D-glucose + UDP


name: Nuclear translocation of catalytic domain of Mst3 (Rattus norvegicus)


name: histone acetyltransferase regulator activity


name: hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 (Caenorhabditis elegans)


name: 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O => 3 H(+) + 3 malonyl-CoA + N-methylanthraniloyl-CoA


name: A + AMP + 2 H(+) + sulfite <=> adenosine 5'-phosphosulfate + AH2


name: ASIC trimers:H+ transport extracellular Na+ to cytosol (Gallus gallus)


name: SGMS1 transfers phosphocholine onto ceramide (Mus musculus)


name: pregnenolone sulfate(out) => pregnenolone sulfate(in)


name: Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Xenopus tropicalis)


name: FUT1,2 transfer fucose to gangliosides (Caenorhabditis elegans)


name: TOPORS SUMOylates IKBKE with SUMO1 (Xenopus tropicalis)


name: 28-norteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 6alpha-hydroxy-28-norteasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: a fatty acyl-[ACP] + L-lysyl-[protein] <=> H(+) + holo-[ACP] + N(6)-(fatty acyl)-L-lysyl-[protein]


name: a ganglioside GA2 + H2O => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-acetyl-beta-D-galactosamine


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Canis familiaris)


name: 2 (S)-lactate(in) + prostaglandin H2(out) => 2 (S)-lactate(out) + prostaglandin H2(in)


name: ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + H(+) + lipid A-core


name: H2O + O2 + propanal => H(+) + H2O2 + propanoate


name: HERC2 and PIAS4 are recruited to DNA DSBs (Canis familiaris)


name: butanoate(out) + dehydroepiandrosterone 3-sulfate(in) => butanoate(in) + dehydroepiandrosterone 3-sulfate(out)


name: (S)-2-amino-6-oxohexanoate + H2O + NADP(+) => 2 H(+) + L-2-aminoadipate + NADPH


name: (R)-S-sulfopantetheine + phosphate => (R)-4'-phospho-S-sulfopantetheine + H2O


name: CYP11A1 cleaves 20a,22b-DHCHOL (Canis familiaris)


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 <=> 1-O-methyl-(13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA (Bos taurus)


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Mus musculus)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Mus musculus)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Homo sapiens)


name: hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity


name: brassicasterol + UDP-alpha-D-glucose = brassicasterol 3-beta-D-glucoside + H(+) + UDP


name: anthranilate + 3 H(+) + NADPH + O2 = catechol + CO2 + NADP(+) + NH4(+)


name: Cinaciguat binds sGC:NO (Canis familiaris)


name: N-phenylhydroxylamine + NADP(+) <=> H(+) + NADPH + nitrosobenzene


name: acetyl-CoA + L-aspartate <=> CoA + H(+) + N-acetyl-L-aspartate


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Xenopus tropicalis)


name: Phosphorylated PKN1 binds androgen receptor (AR) (Sus scrofa)


name: Trimming of peptides in ER (Drosophila melanogaster)


name: 1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate


name: Beclin-1 complex phosphorylates PtdIns (Drosophila melanogaster)


name: Auto-ubiquitination of TRAF3 (Canis familiaris)


name: 2 chloride(out) + H(+)(in) => 2 chloride(in) + H(+)(out)


name: 3xPPCDC:3FMN decarboxylates PPC (Plasmodium falciparum)


name: DYRK2 phosphorylates TP53 (Canis familiaris)


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Schizosaccharomyces pombe)


name: 3 H(+) + hexadecanoyl-CoA + 3 malonyl-CoA = 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity


name: a 1-acyl-sn-glycero-2,3-cyclic phosphate + choline => a 1-acyl-sn-glycero-3-phosphocholine


name: NAGLU hydrolyses heparan chain(2) (Mus musculus)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Homo sapiens)


name: 6-O-phospho-N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine + ADP + H(+) => ATP + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Canis familiaris)


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Dictyostelium discoideum)


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Gallus gallus)


name: CTP(out) + dGTP(in) => CTP(in) + dGTP(out)


name: ATP + H(+) + IC-asc-C7 = diphosphate + IC-asc-C7-AMP


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Sus scrofa)


name: N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Rattus norvegicus)


name: (R)-adrenaline + H2O + O2 => (R)-3,4-dihydroxymandelaldehyde + H2O2 + methylamine


name: dTDP-beta-L-mycarose + erythronolide B <=> 3-O-alpha-L-mycarosylerythronolide B + dTDP + H(+)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)


name: 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Rattus norvegicus)


name: Nuclear translocation of catalytic domain of Mst3 (Bos taurus)


name: NLK translocates to nucleus (Dictyostelium discoideum)


name: 4-hydroxybenzoate(in) + H(+)(out) => 4-hydroxybenzoate(out) + H(+)(in)


name: 3-methyl-1,2-didehydro-2,3-dihydrosqualene + S-adenosyl-L-methionine = 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + H(+) + S-adenosyl-L-homocysteine


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Mus musculus)


name: (+)-copalyl diphosphate = (12E)-labda-8(17),12,14-triene + diphosphate


name: (2R,3S,4S)-leucocyanidin + 2-oxoglutarate + O2 <=> (4S)-2,3-dehydroleucocyanidin + CO2 + H(+) + H2O + succinate


name: NUDT16 hydrolyses IDP to IMP (Rattus norvegicus)


name: MME:Zn2+ binds sacubitrilat (Xenopus tropicalis)


name: Proteasome mediated degradation of Cyclin D1 (Mus musculus)


name: isovitexin + UDP-alpha-D-glucose => H(+) + isovitexin 2''-O-beta-D-glucoside + UDP


name: 3-hydroxy-2-methylpropanoate + NAD(+) => 2-methyl-3-oxopropanoate + H(+) + NADH


name: D-glucose + O2 = 2-dehydro-D-glucose + H2O2


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Homo sapiens)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Rattus norvegicus)


name: thiamine pyrophosphate transmembrane transporter activity


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Homo sapiens)


name: ADP-alpha-D-glucose + alpha-D-glucose 1-phosphate <=> ADP + alpha-maltose 1-phosphate + H(+)


name: an alditol + NADP(+) => an aldose + H(+) + NADPH


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + H(+) + phosphate


name: a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2


name: (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA = (2E,11Z,14Z)-eicosatrienoyl-CoA + H2O


name: eNoSC deacetylates histone H3 (Sus scrofa)


name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) (Bos taurus)


name: XPO1 binds the beta-catenin:CBY complex (Mus musculus)


name: PPARG:RXRA heterodimer binds to fatty acid-like ligands (Homo sapiens)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Sus scrofa)


name: tBID binds to inactive BAK protein (Mus musculus)


name: 2-demethylmenaquinol-10 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-decaprenyl diphosphate + H(+)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Rattus norvegicus)


name: MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Gallus gallus)


name: ATP + decanoate + holo-[ACP] = AMP + decanoyl-[ACP] + diphosphate


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 7alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DAG is acylated to TAG by DGAT1/2 (Caenorhabditis elegans)


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) => 4-deoxy-6-O-methyl-L-threo-hex-4-enopyranuronate + [(1->4)-alpha-D-galacturonosyl methyl ester](n-1)


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Danio rerio)


name: 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O => 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxylate + H(+) + holo-[ACP]


name: calcium-dependent phospholipase A2 activity


name: Hydrolysis of phosphatidylcholine (Homo sapiens)


name: RAPGEF1 binds CRK,CRKL (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H(+) + malonyl-CoA => (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + CoA


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Canis familiaris)


name: H2O + juvenile hormone III => H(+) + juvenile hormone III carboxylate + methanol


name: SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP (Mus musculus)


name: p-STAT5A/B dissociates from the Growth Hormone receptor (Rattus norvegicus)


name: a ganglioside Ac-O-8-GD2(d18:1(4E)) => a ganglioside Ac-O-7-GD2(d18:1(4E))


name: Association of procollagen type XXVII (Homo sapiens)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Danio rerio)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol <=> 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: Formation of hydroxylysyl-pyrrole cross-links (Canis familiaris)


name: a hexanoate ester + H2O <=> an aliphatic alcohol + H(+) + hexanoate


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Homo sapiens)


name: Parenchymal atROL translocates to HSCs (Caenorhabditis elegans)


name: [sulfur carrier]-SH + [sulfur-carrier protein]-L-cysteine => [sulfur carrier]-H + [sulfur-carrier protein]-S-sulfanyl-L-cysteine


name: (2R,3S,11R)-acetylaszonalenin + CoA => (2R,3S,11R)-aszonalenin + acetyl-CoA


name: [sulfur carrier]-SH + AH2 + N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine => 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Rattus norvegicus)


name: CREB1 gene expression is stimulated by MECP2 (Homo sapiens)


name: Caspase-8 cleaves IL1B precursor (Canis familiaris)


name: 5-deoxystrigol ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one => 5-deoxystrigol + H2O


name: glutathione S,S-dioxide + H2O => glutathione + H(+) + sulfite


name: Degradation of multiubiquitinated cell cycle proteins (Bos taurus)


name: DBT transfers BCAA to CoA (Homo sapiens)


name: HPN heterodimer cleaves pro-HGF to form HGF dimer (Sus scrofa)


name: Defective ALG12 does not add mannose to the N-glycan precursor (Homo sapiens)


name: ATP + H2O + L-alanyl-L-glutamine(out) <=> ADP + H(+) + L-alanyl-L-glutamine(in) + phosphate


name: 3'-phosphoadenylyl sulfate + 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] => 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Xenopus tropicalis)


name: SIRT3 deacetylates AcK-IDH2 dimer (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine => 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: 2-(9Z-octadecenoyl)-glycerol + eicosanoyl-CoA <=> 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: pre-VLDL binds lipids to form VLDL (Mus musculus)


name: "phenylalanine aminomutase (D-beta-phenylalanine forming)"


name: SUMOylation of HDAC1 with SUMO1 (Gallus gallus)


name: Calmodulin dissociates KRAS4B from the plasma membrane (Gallus gallus)


name: D-glucarate => 5-dehydro-4-deoxy-D-glucarate + H2O


name: cyclohexa-1,5-diene-1-carbonyl-CoA + H2O = 6-hydroxycyclohex-1-ene-1-carbonyl-CoA


name: CASP9 is phosphorylated at T412 (Sus scrofa)


name: alpha-ribazole 5'-phosphate + H(+) + nicotinate => 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide


name: alpha-D-ribose 1-phosphate + hypoxanthine => inosine + phosphate


name: DARC  is a non-specific receptor for many chemokines (Homo sapiens)


name: ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Bos taurus)


name: 5,10-methylenetetrahydromethanopterin + NADP(+) <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Caenorhabditis elegans)


name: ATP + L-seryl-[myosin light chain] => ADP + H(+) + O-phospho-L-seryl-[myosin light chain]


name: WNTs are secreted in exosomes (Bos taurus)


name: Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Rattus norvegicus)


name: CGA and CGB3 bind to form Human chorionic gonadotropin (hCG) (Homo sapiens)


name: PDPK1 phosphorylates AKT at T308 (Homo sapiens)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) => (6R)-L-erythro-6,7-dihydrobiopterin + H(+) + NADPH


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Homo sapiens)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) <=> (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH


name: NTPDase2 hydrolyzes nucleoside triphosphates (Mus musculus)


name: a 1,2-diacyl-sn-glycerol + H2O <=> a 1-acyl-sn-glycerol + a fatty acid + H(+)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Danio rerio)


name: Isomerization of GlcNAc6P to GlcNAc1P (Sus scrofa)


name: (6E)-8-oxogeraniol + H(+) + NADPH => (6E)-8-hydroxygeraniol + NADP(+)


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Mus musculus)


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O => a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphate


name: KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Sus scrofa)


name: Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK (Homo sapiens)


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Homo sapiens)


name: cis-1,2-dihydro-3-ethylcatechol + NAD(+) => 3-ethylcatechol + H(+) + NADH


name: N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-glucuronate <=> [hyaluronan](n+1) + H(+) + UDP


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Danio rerio)


name: ATP + biotin(in) + H2O <=> ADP + biotin(out) + H(+) + phosphate


name: HRASLS transfer acyl group from PC to PE to form NAPE (Sus scrofa)


name: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O => 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate


name: Formation of the Spliceosomal C* complex (Caenorhabditis elegans)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)


name: (15Z)-3-oxotetracosenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(15Z)-tetracosenoyl-CoA + NADP(+)


name: 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + formate + H(+)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Mus musculus)


name: adenosine(9) in tRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate = (+)-beta-chamigrene + diphosphate


name: P2Y14 receptor can bind to UDP-glucose (Canis familiaris)


name: methylenetetrahydrofolate reductase (NAD(P)H) activity


name: BCL2 binds BCL2 antagonists (Mus musculus)


name: Phosphorylation of CRMPs by Cdk5 (Rattus norvegicus)


name: PPARG binds EBF2-bound gene loci (Homo sapiens)


name: 2-MAG is transacylated to DAG by PNPLA2/3 (Mus musculus)


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-GDP = GDP + glycolate + H(+)


name: Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE (Sus scrofa)


name: ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A => ADP + an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: L-erythro-N-acylsphing-4-enine + UDP-alpha-D-glucose => beta-D-glucosyl-L-erythro-N-acylsphing-4-enine + H(+) + UDP


name: AKT can phosphorylate NR4A1 (NUR77) (Danio rerio)


name: MRN complex binds DNA double strand breaks (Bos taurus)


name: ATP + H2O + L-arginine(out) = ADP + H(+) + L-arginine(in) + phosphate


name: Addition of galactose to Core 6 glycoprotein (Canis familiaris)


name: Recruitment of VAV and BTK to p-SLP-76 (Drosophila melanogaster)


name: Heterodimerization of CEACAMs (Rattus norvegicus)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Drosophila melanogaster)


name: ATP + L-aspartate <=> 4-phospho-L-aspartate + ADP


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Plasmodium falciparum)


name: CDK4 phosphorylates RUNX2 (Homo sapiens)


name: Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)


name: 2-oxoglutarate + L-aspartyl-[protein] + O2 = 3-hydroxy-L-aspartyl-[protein] + CO2 + succinate


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Bos taurus)


name: ARSA removes sulfate from SM3 (Rattus norvegicus)


name: STIM1 oligomerizes (Drosophila melanogaster)


name: L1 trans-homophilic interaction (Mus musculus)


name: L-isoleucine(in) + Na(+)(in) = L-isoleucine(out) + Na(+)(out)


name: a flavone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => a flavanone + O2 + reduced [NADPH--hemoprotein reductase]


name: caldopentamine + 2 H(+) + S-methyl-5'-thioadenosine => norspermine + S-adenosyl 3-(methylsulfanyl)propylamine


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Drosophila melanogaster)


name: SeMet is converted to AdoSeMet by MAT (Xenopus tropicalis)


name: CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 (Homo sapiens)


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Canis familiaris)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Gallus gallus)


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: (2E)-octenoyl-CoA + H(+) + NADPH <=> NADP(+) + octanoyl-CoA


name: PSAP gets cleaved (Dictyostelium discoideum)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Mus musculus)


name: (R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: Formation of clathrin coated vesicle (Caenorhabditis elegans)


name: ALOX5 binds ALOX5 inhibitors (Homo sapiens)


name: 2-methylhexanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = 2-methylhexenoyl-CoA + reduced [electron-transfer flavoprotein]


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycerol


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Sus scrofa)


name: (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanedioate + H(+) + H2O2 => N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2


name: NOTUM releases Hh-Np:GPC5 from the plasma membrane (Bos taurus)


name: p75NTR ICD signals to NF-kB (Gallus gallus)


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Mus musculus)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Caenorhabditis elegans)


name: L-serocholate + taurine => L-serine + taurocholate


name: 2 H(+) + 3 N-(2,3-dihydroxybenzoyl)-L-serine => enterobactin + 3 H2O


name: (4R)-hydroxysphinganine + tetracosanoate => H2O + N-tetracosanoyl-(4R)-hydroxysphinganine


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + a 1,2-diacyl-sn-glycerol => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)


name: 2 L-tyrosyl-tRNA(Tyr) = cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)


name: eIF3 and eIF1A bind to the 40S subunit (Mus musculus)


name: atRAL(membrane) diffuses to atRAL(cytosol) (Homo sapiens)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Drosophila melanogaster)


name: NOTCH1 HD+PEST domain mutants bind DLL4 (Homo sapiens)


name: PLC gamma 2-mediated PIP2 hydrolysis (Xenopus tropicalis)


name: DDR2 binds collagen type I, II, III, V, X fibrils (Caenorhabditis elegans)


name: (E,R)-alpha-bisabolene + diphosphate => (2E,6E)-farnesyl diphosphate


name: TFAP2C translocates to the nucleus (Sus scrofa)


name: RCE1 cleaves S-Farn proRAS proteins (Sus scrofa)


name: 1-O-alkyl-sn-glycerol + ATP = 1-O-alkyl-sn-glycero-3-phosphate + ADP + H(+)


name: [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase] => [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase]


name: NaS2 co-transports sulphate and two sodium ions (Rattus norvegicus)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Dictyostelium discoideum)


name: FarC-PTP4A2 binds RABGGTB (Dictyostelium discoideum)


name: 2-methylbutanoyl-CoA + H2O <=> 2-methylbutanoate + CoA + H(+)


name: D-glutamine + H2O <=> D-glutamate + NH4(+)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: 3-chloro-D-alanine + H2O => chloride + H(+) + NH4(+) + pyruvate


name: unfolded actin/tubulin associates with prefoldin (Homo sapiens)


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Bos taurus)


name: glycylglycyl-L-proline(out) + H(+)(out) <=> glycylglycyl-L-proline(in) + H(+)(in)


name: REV1 inserts dCMP opposite to AP sites in DNA (Schizosaccharomyces pombe)


name: TRPM4,5 transport extracellular Na+ to cytosol (Rattus norvegicus)


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Dictyostelium discoideum)


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + D-glucuronate + H(+) => (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + H2O


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose => 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP


name: C5b:C6:C7 translocates to the plasma membrane (Homo sapiens)


name: (2E)-tetracosenoyl-CoA + H2O2 => O2 + tetracosanoyl-CoA


name: 2 a 2,3-di-O-phytanyl-sn-glycerophospholipid + 2 AH2 + 4 S-adenosyl-L-methionine => 4 5'-deoxyadenosine + 2 A + a glycerol dibiphytanyl glycerol tetraether phospholipid + 4 H(+) + 4 L-methionine


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Dictyostelium discoideum)


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Gallus gallus)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Plasmodium falciparum)


name: STON2 is neddylated (Saccharomyces cerevisiae)


name: PIAS3 SUMOylates MITF with SUMO1 (Rattus norvegicus)


name: ATP + CoA + tetracosanoate = AMP + diphosphate + tetracosanoyl-CoA


name: PDPK1 phosphorylates PKN1,2,3 (Drosophila melanogaster)


name: 4-aminobutanal + H2O + NAD(+) = 4-aminobutanoate + 2 H(+) + NADH


name: ciliary neurotrophic factor receptor activity


name: [(R)-3-hydroxyalkanoate](n+1) + CoA => [(R)-3-hydroxyalkanoate](n) + a (3R)-3-hydroxyacyl-CoA


name: DEGS1 dehydrogenates dihydroceramide (Canis familiaris)


name: guanosine(6) in tRNA + S-adenosyl-L-methionine => H(+) + N(2)-methylguanosine(6) in tRNA + S-adenosyl-L-homocysteine


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate


name: sialic acid transmembrane transporter activity


name: 3-oxodecanoyl-CoA + H(+) + NADH => (3R)-3-hydroxydecanoyl-CoA + NAD(+)


name: Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Caenorhabditis elegans)


name: AKT1 phosphorylates NOTCH4 (Rattus norvegicus)


name: 4-coumaroyl-CoA + agmatine => CoA + H(+) + N-(4-guanidinobutyl)-4-hydroxycinnamamide


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Bos taurus)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Xenopus tropicalis)


name: Association of DFF40 with chromatin (Canis familiaris)


name: LEFTY binds the EGF-CFC coreceptor in the NODAL receptor (Homo sapiens)


name: PDCL binds G-protein beta and TRiC/CCT (Mus musculus)


name: Phosphorylated WTS autophosphorylates (Drosophila melanogaster)


name: Formation of MSH2:MSH6 Complex (Sus scrofa)


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose = alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP + H(+)


name: a ribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate => a ribonucleoside 5'-triphosphate + pyruvate


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O => L-threonyl-[protein] + N-acetyl-D-galactosamine


name: a 5'-end triphospho-guanosine-ribonucleotide-snRNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + O2


name: ADP + gamma-L-glutamyl-L-cysteinyl-beta-alanine + H(+) + phosphate => ATP + beta-alanine + gamma-L-glutamyl-L-cysteine


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Caenorhabditis elegans)


name: SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol (Canis familiaris)


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Mus musculus)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Bos taurus)


name: CYP2S1 4-hydroxylates atRA (Rattus norvegicus)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Xenopus tropicalis)


name: Autoproteolytic cleavage of Hh precursors (Homo sapiens)


name: (2E)-eicosenoyl-CoA + H(+) + NADH => eicosanoyl-CoA + NAD(+)


name: isocitrate dehydrogenase (NADP+) activity


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate <=> ectocarpin C


name: (8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 A + 2 H2O => (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 AH2


name: 7,3',5'-O-trimethylmyricetin + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + syringetin


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Mus musculus)


name: 11-O-acetylcyathatriol + UDP-alpha-D-xylose <=> erinacine Q + H(+) + UDP


name: ATP + L-seryl-[acetyl-CoA carboxylase] => ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase]


name: 2-oxo-N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + O2 + reduced [NADPH--hemoprotein reductase]


name: p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus (Bos taurus)


name: 4-amino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine => 4-methylamino-4-dedimethylamino-anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine


name: octadecanoyl-CoA + sn-glycerol 3-phosphate <=> 1-octadecanoyl-sn-glycero-3-phosphate + CoA


name: MYL9 gene transcription is stimulated by RUNX1:CBFB (Homo sapiens)


name: Factor B binds to C3(H2O) (Homo sapiens)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Plasmodium falciparum)


name: a neolactoside nLc4Cer + UDP-N-acetyl-alpha-D-glucosamine <=> a neolactoside IV(3)-beta-GlcNAc-nLc4Cer + H(+) + UDP


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Drosophila melanogaster)


name: dGTP(out) + UTP(in) => dGTP(in) + UTP(out)


name: 3-(carbamoylamino)-2-methylpropanoate + H(+) => 5,6-dihydrothymine + H2O


name: (R)-2-hydroxyglutarate + NADP(+) = 2-oxoglutarate + H(+) + NADPH


name: ATP + L-threonyl-[Goodpasture antigen-binding protein] <=> ADP + H(+) + O-phospho-L-threonyl-[Goodpasture antigen-binding protein]


name: Dynamin is recruited to the gap junction plaque (Mus musculus)


name: LTA4 is hydolysed to LTB4 by LTA4H (Caenorhabditis elegans)


name: 1-octanoylglycerol + H2O = glycerol + H(+) + octanoate


name: JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Rattus norvegicus)


name: Sprouty sequesters CBL away from active EGFR (Bos taurus)


name: PTPN3 dephosphorylates MAPK12 (Gallus gallus)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Plasmodium falciparum)


name: DNA polymerase epsilon binds at the origin (Schizosaccharomyces pombe)


name: 3'-phosphoadenylyl sulfate + an 11-hydroxyjasmonate => adenosine 3',5'-bisphosphate + an 11-sulfojasmonate + H(+)


name: HHIP binds Hedgehog (Xenopus tropicalis)


name: H(+) + hexadecanoyl-[ACP] + malonyl-[ACP] => 3-oxooctadecanoyl-[ACP] + CO2 + holo-[ACP]


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Rattus norvegicus)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Canis familiaris)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Mus musculus)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Danio rerio)


name: 32-oxoeburicol + O2 + reduced [NADPH--hemoprotein reductase] => 14-demethyleburicol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-hydroxyphenylacetyl-CoA + H2O => 3-hydroxyphenylacetate + CoA + H(+)


name: DIS3L2 binds PABPN1 in PABPN1:uridylated mRNA complex (Homo sapiens)


name: 2 a plastoquinone + 2 H2O + 4 hnu <=> 2 a plastoquinol + O2


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP => delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-alpha-D-glucose


name: chlorophyll a + H2O = chlorophyllide a + H(+) + phytol


name: 3'-phosphoadenylyl sulfate + choline = adenosine 3',5'-bisphosphate + choline sulfate + H(+)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Bos taurus)


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + vanillate => 3,4-dihydroxybenzoate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: SEC24A,B:SEC23A bind SEC22B (Dictyostelium discoideum)


name: H2O + NADP(+) + pseudopaline = (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + 2-oxoglutarate + H(+) + NADPH


name: Phosphorylation of SLP-76 (Mus musculus)


name: beta-D-fructose 6-phosphate + D-erythrose 4-phosphate => D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate


name: DCAKD phosphorylates DP-CoA (Homo sapiens)


name: Binding of CBL to EGFR (Canis familiaris)


name: Phosphorylation and activation of eIF4G by activated S6K1 (Gallus gallus)


name: ADP + glycyl-L-methionine(in) + H(+) + phosphate => ATP + glycyl-L-methionine(out) + H2O


name: ATP + H2O + xanthine(out) => ADP + H(+) + phosphate + xanthine(in)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: ATP + cob(I)yrinate a,c diamide-[corrinoid adenosyltransferase] <=> adenosylcob(III)yrinate a,c-diamide + apo-[corrinoid adenosyltransferase] + triphosphate


name: PIAS1 SUMOylates THRB with SUMO3 (Mus musculus)


name: 2-demethylmenaquinone-8 + dimethyl sulfide + H2O => 2-demethylmenaquinol-8 + dimethyl sulfoxide


name: acetyl-CoA + N(6)-hydroxy-L-lysine = CoA + N(6)-acetyl-N(6)-hydroxy-L-lysine


name: 16alpha,17beta-estriol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: ATP + glutathione(in) + glycocholate(in) + H2O <=> ADP + glutathione(out) + glycocholate(out) + H(+) + phosphate


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + 1-O-alkyl-sn-glycero-3-phosphocholine


name: EGFR phosphorylates EPS15 (Rattus norvegicus)


name: PGH2 is isomerised to PGD2 by HPGDS (Xenopus tropicalis)


name: GDIs block activation of RHOA (Danio rerio)


name: SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane (Rattus norvegicus)


name: CO2 + 2 Fe(II)-[cytochrome c553] + H(+) => 2 Fe(III)-[cytochrome c553] + formate


name: 2,3-dioctanoyl-sn-glycerol + H(+) + octanoate => 1,2,3-trioctanoylglycerol + H2O


name: Detection of damage during initiation of DNA synthesis in S-phase (Saccharomyces cerevisiae)


name: (8E,10R,12Z)-10-hydroperoxyoctadeca-8,12-dienoate => (9Z,12Z)-octadecadienoate + O2


name: Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Mus musculus)


name: Recruitment of XPA and release of CAK  (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> diphosphate + rhizathalene A


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Homo sapiens)


name: GMPS dimer transforms 6TXMP to 6TGMP (Homo sapiens)


name: (24R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (24R)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a carboxylate + ATP + CoA <=> AMP + an acyl-CoA + diphosphate


name: SHPRH polyubiquitinates monoubiquitinated PCNA (Schizosaccharomyces pombe)


name: PIP3 recruits PDPK1 to the membrane (Bos taurus)


name: SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Homo sapiens)


name: dehydrogriseofulvin + H(+) + NADPH => griseofulvin + NADP(+)


name: fluometuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3-[3-(trifluoromethyl)phenyl]-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Interaction of GRB2:SOS complex with p-SHC1 (Homo sapiens)


name: cytidine(50) in tRNA + S-adenosyl-L-methionine => 5-methylcytidine(50) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + L-arginine + NADP(+) => 5-guanidino-2-oxopentanoate + H(+) + NADPH + NH4(+)


name: (2S)-2-amino-4-deoxychorismate + H2O => (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate + pyruvate


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Sus scrofa)


name: 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one (Sus scrofa)


name: Release of 40S and 60S subunits from the 80S ribosome  (Dictyostelium discoideum)


name: Depolymerization of lamin filaments after PKC-mediated phosphorylation (Xenopus tropicalis)


name: hercynylcysteine sulfoxide synthase activity


name: The SRP receptor binds the SRP:nascent peptide:ribosome complex (Homo sapiens)


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Danio rerio)


name: C-terminal Hh fragments are bound by lectins (Sus scrofa)


name: 32-hydroxyeburicol + O2 + reduced [NADPH--hemoprotein reductase] = 32-oxoeburicol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + CoA + sulfoacetate => ADP + phosphate + sulfoacetyl-CoA


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Mus musculus)


name: a 1-[(17Z)-hexacos-17-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-hexacosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: RNA polymerase III type 2 promoter sequence-specific DNA binding


name: CXXC1 and WDR82 bind SET1B complex (Schizosaccharomyces pombe)


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: "acyl-lipid omega-6 desaturase (cytochrome b5)"


name: N-acetyl-alpha-D-glucosamine 1-phosphate => N-acetyl-D-glucosamine 6-phosphate


name: (R)-carnitine + hexadecanedioyl-CoA <=> CoA + O-hexadecanedioyl-L-carnitine


name: H2O + tritetradecanoylglycerol => 2,3-ditetradecanoyl-sn-glycerol + H(+) + tetradecanoate


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Mus musculus)


name: 11-cis-retinyl hexadecanoate + H2O = 11-cis-retinol + H(+) + hexadecanoate


name: Inner coat assembly and cargo binding (Gallus gallus)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Bos taurus)


name: (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate => di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate


name: PINK1 phosphorylates Ub on MOM proteins (Mus musculus)


name: D-galactose + NADP(+) <=> D-galactono-1,5-lactone + H(+) + NADPH


name: 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Gallus gallus)


name: NAD(+) <=> 2'cADPR + H(+) + nicotinamide


name: ATP + holo-[peptidyl-carrier protein] + L-serine <=> AMP + diphosphate + L-seryl-[peptidyl-carrier protein]


name: (9Z)-octadecenoyl-CoA + 1-O-hexadecyl-sn-glycero-3-phosphocholine => 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA


name: β-blockers bind ADRB1,2,3 (Gallus gallus)


name: 3-(3,4-dihydroxyphenyl)propanoate + NAD(+) = (E)-caffeate + H(+) + NADH


name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol (Xenopus tropicalis)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: soyasapogenol A + UDP-alpha-D-glucuronate = H(+) + soyasapogenol A 3-O-beta-D-glucuronate + UDP


name: acetoin + H(+) + NADPH + NH4(+) => 3-aminobutan-2-ol + H2O + NADP(+)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Homo sapiens)


name: The receptor:G-protein complex releases GDP (Sus scrofa)


name: cytidine(72) in tRNA(Cys) + S-adenosyl-L-methionine = 5-methylcytidine(72) in tRNA(Cys) + H(+) + S-adenosyl-L-homocysteine


name: GAB1 recruits CRK,CRKL to MET (Homo sapiens)


name: CDP-2,3-bis-O-(phytanyl)-sn-glycerol + L-serine => 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine + CMP + H(+)


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Mus musculus)


name: PTGIS, CYP8A1 isomerise PGH2 to PGI2 (Homo sapiens)


name: p-Y705-STAT3 binds p-Y693-STAT4 (Drosophila melanogaster)


name: AMP + diphosphate + L-cysteinyl-[peptidyl-carrier protein] => ATP + holo-[peptidyl-carrier protein] + L-cysteine


name: (9Z,12Z)-octadecadienoate + O2 = (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: CBL dissociates from ubiquitinated p-SPRY2 (Rattus norvegicus)


name: TFAP2C homodimer binds MYC and KDM5B (Bos taurus)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Bos taurus)


name: alpha-D-mannosyl-di-(inositol-1-phosphate) + an N-acyl-(4R)-4-hydroxysphinganine + H(+) => an inositol phosphomannosyl-alpha-1->6-inositol-1-phospho-N-acyl-4R-hydroxysphinganine + H2O


name: 1,2,3-trioctanoylglycerol + H2O => 1,2-dioctanoyl-sn-glycerol + H(+) + octanoate


name: Recruitment of VAV1 to p-6Y-SYK (Canis familiaris)


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Canis familiaris)


name: (+)-premalbrancheamide + chloride + FAD + 2 H(+) <=> (+)-isomalbrancheamide B + FADH2


name: kinetin UDP glycosyltransferase activity


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Xenopus tropicalis)


name: 2 sucrose => 1(F)-beta-D-fructosylsucrose + D-glucose


name: acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine


name: Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Mus musculus)


name: Bitter compound binds bitter taste receptor (TAS2R) (Homo sapiens)


name: 1-O-hexadecyl-2-desoxy-2-amino-sn-glycero-3-phosphate + ADP + H(+) => 1-O-hexadecyl-2-amino-sn-glycerol + ATP


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)


name: hydrogencarbonate(out) + iodide(in) = hydrogencarbonate(in) + iodide(out)


name: SUMOylation of Histone H4 with SUMO3 (Homo sapiens)


name: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+) => GDP-alpha-D-mannose + N,N'-diacetylchitobiosyl diphosphodolichol


name: CO2 + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => CO + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ATP + L-leucine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate = ADP + dapdiamide C + H(+) + phosphate


name: CoA + H(+) + N-acetyl-D-glucosamine 6-phosphate => acetyl-CoA + D-glucosamine 6-phosphate


name: D-phenylalanine + H2O + O2 => 3-phenylpyruvate + H2O2 + NH4(+)


name: H2O + methylglyoxal + O2 <=> H(+) + H2O2 + pyruvate


name: FLT3 mutant dimers bind GRB2 (Homo sapiens)


name: CDK1 phosphorylates condensin I (Homo sapiens)


name: CTNNB1 T41 mutants aren't phosphorylated by GSK3beta (Homo sapiens)


name: (2Z,6E,10E)-geranylgeranyl diphosphate + diphosphate => (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate


name: GOT2 transaminates OA and L-Glu (Bos taurus)


name: SUMOylation of HDAC2 with SUMO1 (Bos taurus)


name: acetyl-CoA + N-terminal L-methionyl-[tubulin] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]


name: (1S,5S)-alpha-pinene + diphosphate => (2E)-geranyl diphosphate


name: CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Canis familiaris)


name: (3Z)-decenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(5Z)-dodecenoyl-[ACP] + CO2 + holo-[ACP]


name: "Catalysing the translocation amino acids and peptides"


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Xenopus tropicalis)


name: Formation of ADAR1 homodimer (Sus scrofa)


name: The FA anion diffuses away laterally from UCP (Drosophila melanogaster)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Caenorhabditis elegans)


name: DDR2 binds collagen type I, II, III, V, X fibrils (Gallus gallus)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Canis familiaris)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Gallus gallus)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Canis familiaris)


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Caenorhabditis elegans)


name: 2 oxidized [2Fe-2S]-[ferredoxin] + reduced coenzyme F420-(gamma-L-Glu)(n) <=> 3 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin]


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Schizosaccharomyces pombe)


name: PPP1R3C binds to glycogen:GYG1:GYS1 (Canis familiaris)


name: Uncoupled eNOS favours the formation of superoxide (Sus scrofa)


name: all-trans-retinal + H(+) + NADPH => all-trans-retinol + NADP(+)


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Sus scrofa)


name: CES1trimer hydrolyses ACEI pro-drugs to ACEIs (Gallus gallus)


name: ANKLE2 is deacetylated by SIRT2 (Mus musculus)


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Rattus norvegicus)


name: 4-aminoimidazole + H(+) + H2O = imidazol-4-one + NH4(+)


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Saccharomyces cerevisiae)


name: CES1,CES2 hydrolyze ASA- to ST (Gallus gallus)


name: IKKbeta phosphorylates IkB causing NF-kB to dissociate (Canis familiaris)


name: uridine(35) in tRNA(Tyr) => pseudouridine(35) in tRNA(Tyr)


name: Parathyroid hormone receptor can bind parathyroid hormone (Xenopus tropicalis)


name: Active LTK receptor binds SHC1 (Gallus gallus)


name: ATP + hypotaurocyamine <=> ADP + H(+) + N(omega)-phosphohypotaurocyamine


name: SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Homo sapiens)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Drosophila melanogaster)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Gallus gallus)


name: an N-acylsphing-4-enine + UDP-alpha-D-galactose => H(+) + N-acyl-D-galactosylsphing-4-enine + UDP


name: MYSM1 deubiquitinates Histone H2A (Mus musculus)


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Rattus norvegicus)


name: amicoumacin A + phosphate => amicoumacin A 2-phosphate + H2O


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Rattus norvegicus)


name: HPO dimer binds to RASSF (Drosophila melanogaster)


name: RHOQ binds effectors at the plasma membrane (Gallus gallus)


name: SCF-FBXL7 ubiquitinates AURKA (Mus musculus)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Rattus norvegicus)


name: Release of E3 from polyubiquitinated substrate (Mus musculus)


name: Interaction of integrin alpha9beta1 with Tenascin-C (Bos taurus)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Caenorhabditis elegans)


name: Phosphorylation of PLC-gamma by p-BTK/p-SYK (Canis familiaris)


name: (S)-indan-1-ol + NAD(+) <=> H(+) + indan-1-one + NADH


name: GDP-alpha-D-rhamnose + NAD(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADH


name: Dab2 is recruited to the junctional plaques (Mus musculus)


name: FUT2 transfers Fuc to LeX to form LeY (Sus scrofa)


name: ORC1 binds to H4K20me2 (Schizosaccharomyces pombe)


name: [LarE protein]-L-cysteine + ATP + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide <=> [LarE protein]-dehydroalanine + AMP + diphosphate + H(+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: Liganded-ALK dimer binds type I ALK-binding TKIs (Homo sapiens)


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Caenorhabditis elegans)


name: 3-oxo-(23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA + CO2 + CoA => (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + H(+) + malonyl-CoA


name: Hydroxyl radicals oxidize ST to 2,3-DHBA (Homo sapiens)


name: butanoyl-[ACP] + NAD(+) => (2E)-butenoyl-[ACP] + H(+) + NADH


name: ITPA hydrolyses XTP to XMP (Danio rerio)


name: (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH => (6S,9R)-vomifoliol + NAD(+)


name: CCR4-NOT complex deadenylates mRNA (Homo sapiens)


name: Phosphorylation of WWTR1 (TAZ) by LATS2 (Canis familiaris)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2 <=> (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O


name: Mo-molybdopterin cofactor sulfurase activity


name: 2 a Fe(III)-siderophore + NADPH => 2 a Fe(II)-siderophore + H(+) + NADP(+)


name: VENTX stimulates CSF1R (M-CSF-R) expression (Homo sapiens)


name: p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane (Homo sapiens)


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Bos taurus)


name: a ribonucleoside 5'-phosphate + diphosphate + H(+) => a ribonucleoside 5'-triphosphate + H2O


name: ATP + beta-alanine + L-arginine = ADP + beta-alanyl-L-arginine + H(+) + phosphate


name: SCUBE1, SCUBE3 oligomerize (Gallus gallus)


name: 7 diphosphate + tri-trans,hepta-cis-undecaprenyl diphosphate => geranylgeranyl diphosphate + 7 isopentenyl diphosphate


name: a 2-acyl-4,6-diprenylphloroglucinol + diphosphate => a 2-acyl-4-prenylphloroglucinol + dimethylallyl diphosphate


name: H(+) + L-gulonate => H2O + L-gulono-1,4-lactone


name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Xenopus tropicalis)


name: SYK binds to integrin alphaIIb beta3 (Bos taurus)


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Saccharomyces cerevisiae)


name: CRY is phosphorylated by SGG (Drosophila melanogaster)


name: H(+) + NADPH + precondylocarpine acetate => dihydroprecondylocarpine acetate + NADP(+)


name: Calmodulin activates Cam-PDE 1 (Drosophila melanogaster)


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Bos taurus)


name: pseudouridine(54) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylpseudouridine(54) in tRNA + S-adenosyl-L-homocysteine


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Schizosaccharomyces pombe)


name: 4-hydroxybenzalacetone + 2 CO2 + 2 CoA => 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA


name: 2-acyl LPG is acylated to PG by LPGAT (Canis familiaris)


name: PPANT translocates from extracellular region to cytosol (Homo sapiens)


name: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH


name: RRAGA,B hydrolyzes GTP (Dictyostelium discoideum)


name: adenosine 3',5'-bisphosphate + dopamine 4-O-sulfate + H(+) => 3'-phosphoadenylyl sulfate + dopamine


name: a dicarboxylate(in) + estrone 3-sulfate(out) = a dicarboxylate(out) + estrone 3-sulfate(in)


name: ABCC5 transports TPMP substrates from cytosol to extracellular region (Canis familiaris)


name: RNA polymerase II general transcription initiation factor activity


name: C-ter TLR7 dimer binds imiquimod (Canis familiaris)


name: VD3 dissociates from GC (Xenopus tropicalis)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Canis familiaris)


name: NDUF subunits bind to form the IP subcomplex (Sus scrofa)


name: H(+) + H2O + pheophorbide a = CO2 + methanol + pyropheophorbide a


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Sus scrofa)


name: Interaction of other adapter proteins with p-KIT (Xenopus tropicalis)


name: D-gluconate => 2-dehydro-3-deoxy-D-gluconate + H2O


name: Formation of the Cleavage and Polyadenylation Complex (Bos taurus)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Xenopus tropicalis)


name: all-trans-(4S)-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase] => all-trans-(4S,16)-dihydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+) => 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Canis familiaris)


name: NKG2D homodimer interacting with ligands (Mus musculus)


name: Phosphorylation and activation of Ezrin (Canis familiaris)


name: lanosterol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Passive I- efflux mediated by SLC5A8 (Drosophila melanogaster)


name: (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + CO2 + CoA


name: H(+) + N-tetracosanoylsphinganine + NADPH + O2 = H2O + N-(2-hydroxytetracosanoyl)-sphinganine + NADP(+)


name: L-hexahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-9-(methylsulfanyl)nonanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Caspase-3 cleaves pro-interleukin-16 (Sus scrofa)


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Bos taurus)


name: quillate + UDP-alpha-D-glucose <=> quillaic acid 28-beta-D-glucoside + UDP


name: 2 (2E,6E)-farnesyl diphosphate + H(+) + NADPH <=> 2 diphosphate + NADP(+) + squalene


name: (2E,6E)-farnesyl diphosphate <=> (-)-beta-barbatene + diphosphate


name: (15Z)-3-oxotetracosenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(15Z)-tetracosenoyl-CoA + NADP(+)


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Bos taurus)


name: cyclo(L-tryptophyl-L-alanyl) + dimethylallyl diphosphate = diphosphate + preechinulin


name: FMO2:FAD:Mg2+ S-oxidises MTZ (Bos taurus)


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Xenopus tropicalis)


name: Granzyme-B activates BID by cleavage (Rattus norvegicus)


name: an R-cob(III)alamin(out) + ATP + H2O => ADP + an R-cob(III)alamin(in) + H(+) + phosphate


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Bos taurus)


name: DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Rattus norvegicus)


name: IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Canis familiaris)


name: carbon disulfide + H2O <=> carbonyl sulfide + H(+) + hydrogen sulfide


name: 2-oxoglutarate + O2 + verruculide A => chrodrimanin T + CO2 + succinate


name: inositol tetrakisphosphate 5-kinase activity


name: GTP + S-adenosyl-L-methionine => N(7)-methyl-GTP + S-adenosyl-L-homocysteine


name: ATP + H2O + sitosterol(in) => ADP + H(+) + phosphate + sitosterol(out)


name: FOXO3 binds SOD2 gene promoter (Homo sapiens)


name: N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-homocysteine


name: acetone + H(+) + NADPH => NADP(+) + propan-2-ol


name: 3-dehydrolevoglucosan + H(+) + NADH => levoglucosan + NAD(+)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Bos taurus)


name: OAS1 produces oligoadenylates (Homo sapiens)


name: 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA => 6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Mus musculus)


name: PDGF binds to extracellular matrix proteins (Xenopus tropicalis)


name: oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water


name: "With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"


name: Activated CIT binds KIF14 and PRC1 (Drosophila melanogaster)


name: β1,2-agonists bind ADRB1,2 (Homo sapiens)


name: a ganglioside GQ1b (d18:1(4E)) + H2O => a ganglioside GT1b (d18:1(4E)) + N-acetylneuraminate


name: Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA (Gallus gallus)


name: The retrograde IFT train dissociates (Canis familiaris)


name: Regulation of IL6 transcription (Homo sapiens)


name: H2O + L-arginine + NAD(+) <=> 5-guanidino-2-oxopentanoate + H(+) + NADH + NH4(+)


name: (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH


name: Caspase-mediated cleavage of gelsolin (Gallus gallus)


name: sphing-4-enine + UDP-alpha-D-galactose <=> beta-D-galactosyl-(1<->1)-sphing-4-enine + H(+) + UDP


name: (S)-S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine = 3-O-acetylpapaveroxine + H(+) + S-adenosyl-L-homocysteine


name: GRKs bind ADRB2:Catecholamine (Sus scrofa)


name: PSAP(195-273) forms a dimer (Mus musculus)


name: IL35 binds IL6ST:IL6ST receptor (Sus scrofa)


name: S-adenosyl-L-methionine + uridine(1939) in 23S rRNA <=> 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Canis familiaris)


name: a 3-vinylbacteriochlorophyllide d + H2O => a bacteriochlorophyllide d


name: Defective CYP11A1 does not cleave 20a,22b-DHCHOL (Homo sapiens)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Danio rerio)


name: SLC29A1 transports RBV from extracellular region to cytosol (Mus musculus)


name: Translocation of Cdc25B to the cytoplasm (Homo sapiens)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: 3-hydroxypentacecilide A + H(+) + NADPH + O2 <=> chrodrimanin F + H2O + NADP(+)


name: [G-protein-coupled receptor] + ATP => [G-protein-coupled receptor]-phosphate + ADP + H(+)


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Xenopus tropicalis)


name: PAK1-3 dimer disassociates (Drosophila melanogaster)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: aclacinomycin T + H2O <=> 15-demethylaclacinomycin T + methanol


name: HEXA cleaves the terminal GalNAc from small HA fragments (Homo sapiens)


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Homo sapiens)


name: Phosphorylation of MEF2 proteins by p38 (Homo sapiens)


name: N-hydroxylation of 4-aminobiphenyl (Sus scrofa)


name: (2R)-hydroxybutanoyl-CoA => (2E)-butenoyl-CoA + H2O


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Sus scrofa)


name: 5,6-dihydrouridine(17) in tRNA + NAD(+) <=> H(+) + NADH + uridine(17) in tRNA


name: holo-[(phenol)carboxyphthiodiolenone synthase] + icosanoyl-AMP <=> AMP + H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: H(+)(in) + L-aspartate(out) + phosphate(in) => H(+)(out) + L-aspartate(in) + phosphate(out)


name: CMP + ganglioside GT1a alpha + H(+) => a ganglioside GD1alpha + CMP-N-acetyl-beta-neuraminate


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Rattus norvegicus)


name: MAPK6 is degraded by the 26S proteasome (Schizosaccharomyces pombe)


name: 2-methyl-(2E)-pentadecenoyl-CoA + H2O2 => (2S)-methylpentadecanoyl-CoA + O2


name: ub UBXN7 is degraded by the 26S proteasome (Drosophila melanogaster)


name: (+)-artemisinic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-amorpha-4,11-diene + O2 + reduced [NADPH--hemoprotein reductase]


name: Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol (Homo sapiens)


name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)


name: Mcm2-7 is phosphorylated by DDK (Bos taurus)


name: Phosphorylation of CARMA1 (Rattus norvegicus)


name: a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Drosophila melanogaster)


name: Stalling of DNA replication fork and RPA binding (Rattus norvegicus)


name: STAT4 binds IL12RB2:IL12RB2 (Xenopus tropicalis)


name: PLCG1 phosphorylation by p-EGFR:p-ERBB2 (Homo sapiens)


name: (9Z)-hexadecenoyl-CoA + AH2 + O2 => (9Z,12Z)-hexadecadienoyl-CoA + A + 2 H2O


name: siderophore uptake transmembrane transporter activity