name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Dictyostelium discoideum)


name: decanoyl-AMP + diphosphate => ATP + decanoate + H(+)


name: L-homoserine + succinyl-CoA = CoA + O-succinyl-L-homoserine


name: 10-deacetylbaccatin III + acetyl-CoA <=> baccatin III + CoA


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Mus musculus)


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex  (Mus musculus)


name: an acyl-CoA + sn-glycero-3-phosphoethanolamine => a monoacyl-sn-glycero-3-phosphoethanolamine + CoA


name: sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen (Rattus norvegicus)


name: ABC7, mABC1 and mABC2 mediate heme transport (Rattus norvegicus)


name: 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 <=> 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Homo sapiens)


name: Association of procollagen type XV (Homo sapiens)


name: Inactivation of Rho-GTP by p190RhoGAP (Bos taurus)


name: dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + H(+) + sulfate


name: methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity


name: H2O + O-phospho-L-seryl-tRNA(Sec) + selenophosphate => L-selenocysteinyl-tRNA(Sec) + 2 phosphate


name: griseophenone B + H(+) + O2 + reduced [NADPH--hemoprotein reductase] <=> desmethyl-dehydrogriseofulvin + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Schizosaccharomyces pombe)


name: Initial proteolyis of Ii by aspartic proteases to lip22 (Canis familiaris)


name: L-homocysteine = 2-aminobut-2-enoate + H(+) + hydrogen sulfide


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Plasmodium falciparum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol = 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Homo sapiens)


name: L-aspartate + menaquinone-8 => iminosuccinate + menaquinol-8


name: 3-sulfinopropanoyl-CoA + H2O => H(+) + propanoyl-CoA + sulfite


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA => (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA


name: a 3-dehydro-D-glucoside + H(+) + NADH => a D-glucoside + NAD(+)


name: L-phenylalanine + taurocholate = L-phenylalanocholate + taurine


name: 2-oxoglutarate + 2 H(+) + NADPH => 2,5-dioxopentanoate + H2O + NADP(+)


name: β-blockers bind ADRB1,2,3 (Drosophila melanogaster)


name: Formation of the PINCH-ILK-parvin complex (Mus musculus)


name: 2,3-dihydroxy-p-cumate + O2 = 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+)


name: Frataxin binds iron (Dictyostelium discoideum)


name: RAC2 GAPs stimulate RAC2 GTPase activity (Drosophila melanogaster)


name: P2Y6 receptor can bind to UDP (Rattus norvegicus)


name: a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate => a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose 6-phosphate + H(+)


name: H(+) + hercynine + S-adenosyl-L-homocysteine => N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-methionine


name: Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Rattus norvegicus)


name: a 1,2-saturated fatty acid + O2 => a (2R)-2-hydroperoxy fatty acid


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Gallus gallus)


name: 5alpha-cholest-7-en-3-one + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> (25S)-Delta7-dafachronate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: n acetate + chitosan => [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O


name: Autophosphorylation of BTK/ITK (Sus scrofa)


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Sus scrofa)


name: cis-1,2-dihydrobenzene-1,2-diol + NAD(+) => benzene + H(+) + NADH + O2


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Mus musculus)


name: estrone 3-sulfate(in) + H(+)(out) => estrone 3-sulfate(out) + H(+)(in)


name: Activation of Ca-permeable Kainate receptors (Gallus gallus)


name: myo-inositol + NAD(+) = H(+) + NADH + scyllo-inosose


name: GTP + L-lysyl-[protein] => diphosphate + H(+) + N(epsilon)-GMP-L-lysyl-[protein]


name: 6beta-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase]


name: S100A8:S100A9 binds Zn2+ (Canis familiaris)


name: kainate receptor binds glutamate (Homo sapiens)


name: L-lysyl-L-alpha-amino acid(out) => L-lysyl-L-alpha-amino acid(in)


name: (E,E)-piperoyl-CoA + piperidine <=> CoA + H(+) + piperine


name: D-fructose 6-phosphate + L-glutamine => D-glucosamine 6-phosphate + L-glutamate


name: ATP + L-seryl-[pyruvate dehydrogenase E1 alpha subunit] = ADP + H(+) + O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit]


name: "[pyruvate dehydrogenase (acetyl-transferring)] kinase"


name: CSNK2-mediated phosphorylation of DVL (Canis familiaris)


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Dictyostelium discoideum)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Xenopus tropicalis)


name: (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP] => 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine


name: cyclohexanol + NAD(+) <=> cyclohexanone + H(+) + NADH


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde = H(+) + H2O + quinolinate


name: SRC phosphorylates RUNX3 (Gallus gallus)


name: 2-oxoglutarate(out) + glutarate(in) = 2-oxoglutarate(in) + glutarate(out)


name: Interleukin-27 binds Interleukin-27 receptor (Canis familiaris)


name: NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates (Homo sapiens)


name: CYP39A1 7-hydroxylates 24OH-CHOL (Rattus norvegicus)


name: (E)-(indol-3-yl)acetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] => (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: sulfate(out) + sulfite(in) = sulfate(in) + sulfite(out)


name: RNA Pol II initiates transcription from damaged DNA template (Sus scrofa)


name: Expression of peptide bound class I MHC on cell surface (Canis familiaris)


name: (R)-carvone + AH2 => (1R,4R)-dihydrocarvone + A


name: NFE2 binds the beta globin locus control region (Danio rerio)


name: AKT phosphorylates CREB1 (Drosophila melanogaster)


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Mus musculus)


name: 18-hydroxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = aldosterone + 2 H2O + 2 oxidized [adrenodoxin]


name: complement component C4b receptor activity


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Homo sapiens)


name: FOXO3-dependent CDKN1B gene expression (Homo sapiens)


name: CDK1 phosphorylates VCPIP1 (Rattus norvegicus)


name: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H2O


name: PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Canis familiaris)


name: H(+) + holo-[ACP] + octadecanoate => H2O + octadecanoyl-[ACP]


name: FMO1:FAD oxidizes HTAU to TAU (Bos taurus)


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Xenopus tropicalis)


name: PREX2 binds PTEN and inhibits it (Homo sapiens)


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Caenorhabditis elegans)


name: 2 L-ascorbate + O2 <=> 2 H2O + 2 L-dehydroascorbate


name: HV1-mediated H+ transfer (Gallus gallus)


name: INTL1 binds bacterial glycans (Danio rerio)


name: GM2A binds and mobilizes ligands (Canis familiaris)


name: deoxycholate + NADP(+) <=> 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: 9-cis-retinol + tetradecanoyl-CoA <=> 9-cis-retinyl tetradecanoate + CoA


name: Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Canis familiaris)


name: 5-formimidoyltetrahydrofolate + glycine => (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine


name: dimethylallyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + nerylneryl diphosphate


name: RABGGTA and RABGGTB bind (Drosophila melanogaster)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Rattus norvegicus)


name: coproporphyrin I(out) => coproporphyrin I(in)


name: 2 AH2 + 2 ATP + benzoate + L-phenylalanine = 2 A + 2 AMP + 2 diphosphate + H(+) + N-benzoyl-L-phenylalaninol


name: PA is dephosphorylated to DAG by LPIN (Drosophila melanogaster)


name: 2 S-adenosyl-L-methionine + trans-resveratrol = 2 H(+) + pterostilbene + 2 S-adenosyl-L-homocysteine


name: ADP + H(+) + leukotriene C4(in) + phosphate => ATP + H2O + leukotriene C4(out)


name: 13-cis-retinol + NADP(+) = 13-cis-retinal + H(+) + NADPH


name: gibberellin A12 aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => ent-7alpha-hydroxykaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: H(+)(out) + L-leucyl-L-proline(out) => H(+)(in) + L-leucyl-L-proline(in)


name: 23S rRNA (guanine(2445)-N(2))-methyltransferase activity


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Schizosaccharomyces pombe)


name: bonnadiene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Canis familiaris)


name: p-PKR dimer phosphorylates PPP2R5A (Canis familiaris)


name: guanosine(10) in tRNA + 2 S-adenosyl-L-methionine <=> 2 H(+) + N(2)-dimethylguanosine(10) in tRNA + 2 S-adenosyl-L-homocysteine


name: Bile salts dissociate from FABP6 (Drosophila melanogaster)


name: Co(II)-factor III + H(+) + S-adenosyl-L-methionine => Co(II)-factor IV + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = a 1-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acid + H(+)


name: 5-aminopentanoate + acetyl-CoA + 20 H(+) + 8 malonyl-CoA + 13 NADPH <=> 8 CO2 + 9 CoA + 7 H2O + 13 NADP(+) + wortmanamide B


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: IL7:IL7R:JAK1 binds IL2RG:JAK3 (Mus musculus)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Canis familiaris)


name: a very long-chain fatty acid(in) + ATP + H2O <=> a very long-chain fatty acid(out) + ADP + H(+) + phosphate


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Caenorhabditis elegans)


name: (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al + 2-cis,4-trans-xanthoxin => 9-cis-violaxanthin + O2


name: Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Canis familiaris)


name: 2 Na(+)(out) + pregnenolone sulfate(out) => 2 Na(+)(in) + pregnenolone sulfate(in)


name: (indol-3-yl)acetyl-L-aspartate + H2O = (indol-3-yl)acetate + L-aspartate


name: 7-oxopregnenolone + H(+) + NADPH => 7beta-hydroxypregnenolone + NADP(+)


name: ATP + Ca(2+)(in) + H2O = ADP + Ca(2+)(out) + H(+) + phosphate


name: an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> an N-acyl-sphinga-4E,14Z-dienine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2xTNFR2 binds TNFA trimer:TNFR2 (Mus musculus)


name: beta-catenin is replaced by repression complexes at the promoter (Drosophila melanogaster)


name: ABHD4 hydrolyses NAPE (Caenorhabditis elegans)


name: BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Caenorhabditis elegans)


name: 7,9,9'-tri-cis-neurosporene + a quinone = 7,7',9,9'-tetra-cis-lycopene + a quinol


name: RHOD binds effectors at the endosome membrane (Drosophila melanogaster)


name: CSN polymer binds CaPO4 (Rattus norvegicus)


name: (6R)-10-formyltetrahydrofolate + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose <=> (6S)-5,6,7,8-tetrahydrofolate + dTDP-4-formamido-4,6-dideoxy-alpha-D-glucose + H(+)


name: MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Sus scrofa)


name: biotinate sulfoxide + H(+) + NADPH = biotin + H2O + NADP(+)


name: EP400 binds CDKN1A promoter (Xenopus tropicalis)


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Dictyostelium discoideum)


name: (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA => (9Z,12Z)-octadecadienoyl-CoA + H(+) + malonyl-CoA


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Dictyostelium discoideum)


name: Dissociation of Cdc20 from APC/C complex (Homo sapiens)


name: 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2 <=> CO2 + H2O + NAD(+) + naphthalene-1,2-diol


name: a nitrile + 2 H2O <=> a carboxylate + NH4(+)


name: an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine = an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine


name: 4,8-dimethylnonanoyl-CoA + H2O => 4,8-dimethylnonanoate + CoA + H(+)


name: hydroxymethylbilane => H2O + uroporphyrinogen III


name: UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity


name: adenosine 3',5'-bisphosphate + H(+) + UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate => 3'-phosphoadenylyl sulfate + UDP-N-acetyl-alpha-D-galactosamine 4-sulfate


name: CoA + O-propanoyl-(R)-carnitine => (R)-carnitine + propanoyl-CoA


name: 5-hydroxyisourate + H2O + NADP(+) => H(+) + NADPH + O2 + urate


name: 2,3-dinitrotoluene + NADH + O2 <=> 4-methyl-3-nitrocatechol + H(+) + NAD(+) + nitrite


name: a ganglioside GD1a + acetyl-CoA <=> a ganglioside Ac-O-7-GD1a + CoA


name: Phosphorylation of WWTR1 (TAZ) by LATS2 (Caenorhabditis elegans)


name: AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Sus scrofa)


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)


name: hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides


name: CAD hexamer transforms CAP to N-carb-L-Asp (Bos taurus)


name: NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Xenopus tropicalis)


name: (2S)-2-acetamido-4-aminobutanoate => H2O + L-ectoine


name: saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity


name: minor groove of adenine-thymine-rich DNA binding


name: SPTLC complexes transfer acyl-CoA onto serine (Rattus norvegicus)


name: 4'-O-methylnorbelladine + O2 + reduced [NADPH--hemoprotein reductase] <=> (10bR,4aS)-noroxomaritidine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Recruitment of Dna2 endonuclease (Dictyostelium discoideum)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Gallus gallus)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Sus scrofa)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)


name: SUMOylation of HIPK2 with SUMO1 (Homo sapiens)


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Caenorhabditis elegans)


name: NAAA hydrolyses NAEs to FAs and ethanolamine (Gallus gallus)


name: 2 H(+) + NADPH + riboflavin => NADP(+) + reduced riboflavin


name: abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Homo sapiens)


name: H2O + N-acetyltyramine = acetate + tyramine


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Homo sapiens)


name: Liganded-ALK dimer binds type I ALK-binding TKIs (Danio rerio)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA => 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: ammeline + H(+) + H2O <=> ammelide + NH4(+)


name: (+)-secoisolariciresinol + NADP(+) <=> (-)-lariciresinol + H(+) + NADPH


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Xenopus tropicalis)


name: SERPINB13 gene expression is inhibited by RUNX1:CBFB (Homo sapiens)


name: monodehydroascorbate reductase (NADH) activity


name: beta-alanine + L-arginine = 3-guanidinopropanoate + L-ornithine


name: (15Z)-tetracosenoyl-CoA + sphinganine => CoA + H(+) + N-(15Z-tetracosenoyl)-sphinganine


name: chloride(in) + 2 hydrogencarbonate(out) + Na(+)(out) <=> chloride(out) + 2 hydrogencarbonate(in) + Na(+)(in)


name: (2S)-2-isopropylmalate + CoA + H(+) => 3-methyl-2-oxobutanoate + acetyl-CoA + H2O


name: H(+) + menaquinone-4 + NADH <=> menaquinol-4 + NAD(+)


name: Tyrosine is diiodinated (Canis familiaris)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Rattus norvegicus)


name: WNT5A-FZD4 recruits DVL2 (Xenopus tropicalis)


name: (1S)-1,23-dihydroxy-24,25,26,27-tetranorcalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (1S)-1-hydroxy-23-oxo-24,25,26,27-tetranorcalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: JAK1-activated RAF1 phosphorylates MAPKs (Canis familiaris)


name: CysS248-MPST:TXN2 dissociates (Xenopus tropicalis)


name: CYSLT2 binds LTC4,LTD4,LTE4 (Canis familiaris)


name: NUDT12 hydrolyses NADH to NMNH (Homo sapiens)


name: PEX3:PEX19:class I PMP dissociates (Bos taurus)


name: [thyroglobulin]-3-iodo-L-tyrosine + H(+) + H2O2 + iodide = [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Gallus gallus)


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Homo sapiens)


name: H(+) + N,N-dihydroxy-L-valine => (E)-2-methylpropanal oxime + CO2 + H2O


name: Glycosylation of Hh (Drosophila melanogaster)


name: Phosphorylation of JAK2 (Rattus norvegicus)


name: a cholesterol ester + H2O => a fatty acid + cholesterol + H(+)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + H2O + L-tyrosine


name: Co(I)-[methanol-specific corrinoid protein] + H(+) + methanol <=> H2O + methyl-Co(III)-[methanol-specific corrinoid protein]


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Bos taurus)


name: a quinone + succinate => a quinol + fumarate


name: a dolichyl phosphate + UDP-alpha-D-xylose = a dolichyl D-xylosyl phosphate + UDP


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Danio rerio)


name: N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Bos taurus)


name: ALB binds extracellular heme (Mus musculus)


name: AAMP binds to TBXA2R (Rattus norvegicus)


name: Androgens binds AR (in the HSP90 chaperone complex) (Xenopus tropicalis)


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (9Z,12E)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Bos taurus)


name: Phosphorylation of LAT by p-SYK (Rattus norvegicus)


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Canis familiaris)


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Sus scrofa)


name: DMBT1 binds SFTPD 12mer, SFTPAs (Sus scrofa)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + cholesterol => (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterol + CoA


name: 4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA => 4 CO2 + 4 CoA + trans-resveratrol


name: L-phenylalanine(out) + S-methylmercury-L-cysteine(in) = L-phenylalanine(in) + S-methylmercury-L-cysteine(out)


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Sus scrofa)


name: PKC-delta translocates to plasma membrane (Danio rerio)


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Xenopus tropicalis)


name: TP53BP1 recruits DCLRE1C to ATM (Mus musculus)


name: RBX1:CUL3 dissociates from forming autophagosome (Mus musculus)


name: dTDP-beta-L-rhamnose + N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol => alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + dTDP + H(+)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Sus scrofa)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol => 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Schizosaccharomyces pombe)


name: MAOA:FAD oxidatively deaminates of 5HT (Sus scrofa)


name: H2O + N,N'-diacetylchitobiono-1,5-lactone => H(+) + N,N'-diacetylchitobionate


name: NTHL1 glycosylase mediated recognition and binding of dihydrouracil (Homo sapiens)


name: RHOG GAPs stimulate RHOG GTPase activity (Gallus gallus)


name: Co-precorrin-6B + NAD(+) = Co-precorrin-6A + H(+) + NADH


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Sus scrofa)


name: (3R)-hydroxyhexacosanoyl-CoA => (2E)-hexacosenoyl-CoA + H2O


name: Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP (Homo sapiens)


name: SLC25A1 exchanges CIT and MAL (Danio rerio)


name: 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA => 3 H(+) + hexanoyl-CoA + 3 malonyl-CoA


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Caenorhabditis elegans)


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Rattus norvegicus)


name: SMURF1 gene expression is stimulated by RUNX2 (Homo sapiens)


name: Localization of CBL:GRB2 to the membrane (Caenorhabditis elegans)


name: Spontaneous hydrolysis of C3 thioester (Homo sapiens)


name: Formation of the CTF18-RFC(7s) complex (Bos taurus)


name: (-)-secoisolariciresinol + NADP(+) => (+)-lariciresinol + H(+) + NADPH


name: CCND3,(CCND1,CCND2) binds RUNX1 (Rattus norvegicus)


name: TRAIL binds TRAIL receptors (Mus musculus)


name: Protein kinase C, alpha type phosphorylates MARCKS (Canis familiaris)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Homo sapiens)


name: Granzyme-B activates BID by cleavage (Gallus gallus)


name: abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase] = abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FLIP(S) and procaspase-8 form heterodimer (Mus musculus)


name: FADH2 + O2 + styrene => (S)-styrene oxide + FAD + H(+) + H2O


name: (3R)-hydroxytetradecanoyl-CoA <=> (2E)-tetradecenoyl-CoA + H2O


name: CBL binds to GRB2 (Drosophila melanogaster)


name: STAT1,STAT3 binds PKR (Canis familiaris)


name: ADH5 oxidises S-HMGSH to S-FGSH (Mus musculus)


name: 3''-dehydroisoorientin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid (Canis familiaris)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z,12Z)-octadecadienoate + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+)


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Canis familiaris)


name: COASY phosphorylates DP-CoA (Saccharomyces cerevisiae)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+) + octadecanoate => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O


name: RET tyrosine phosphorylation (Rattus norvegicus)


name: 2 Na(+)(out) + urate(out) <=> 2 Na(+)(in) + urate(in)


name: dUTP(in) + UTP(out) => dUTP(out) + UTP(in)


name: MITF-M-dependent ATP6V1H gene expression (Homo sapiens)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: CDK2 phosphorylates TP53 (Canis familiaris)


name: dimethyl sulfoxide + menaquinol-8 => dimethyl sulfide + H2O + menaquinone-8


name: ATXN3 deubiquitinates polyUb-PARK2 (Homo sapiens)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Mus musculus)


name: H2O + pyridoxal 5'-phosphate => phosphate + pyridoxal


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Drosophila melanogaster)


name: BP230 interacts with keretin K5/K14 (Homo sapiens)


name: (R)-carnitine(in) + glycine betaine(out) => (R)-carnitine(out) + glycine betaine(in)


name: 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-heptadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Mus musculus)


name: FABP5:atRA translocates from cytosol to nucleoplasm (Caenorhabditis elegans)


name: Fucosylation of Pre-NOTCH by POFUT1 (Homo sapiens)


name: deaminated base DNA N-glycosylase activity


name: MMACHC dealkylates RCbl (Rattus norvegicus)


name: 1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O => 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide


name: acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) => CO + CoA + methyl-Co(III)-[corrinoid Fe-S protein]


name: an N-(fatty acyl)-L-asparagine + H2O <=> a fatty acid + L-asparagine


name: hydroxymethylbutenyl pyrophosphate reductase activity


name: USP17L2 deubiquitinates RCE1 (Bos taurus)


name: RUNX1 binds the core TAL1 complex (Canis familiaris)


name: ATP + N(6)-(D-erythrulosyl)-L-lysyl-[protein] = ADP + H(+) + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein]


name: RNA polymerase III cis-regulatory region sequence-specific DNA binding


name: IL6ST is tyrosine phosphorylated (Danio rerio)


name: BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Sus scrofa)


name: MARCO:ligand is endocytosed (Homo sapiens)


name: p-S207 KARS1 dimer translocates to the nucleus (Canis familiaris)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a cardiolipin + ethanolamine


name: ATP + D-galactose(out) + H2O <=> ADP + D-galactose(in) + H(+) + phosphate


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Drosophila melanogaster)


name: DHAP is converted to G3P by GPD1/GPD1L (Danio rerio)


name: Nuclear VBC complex ubiquitinylates HIF-alpha (Sus scrofa)


name: a ubiquinol + nitrate <=> a ubiquinone + H2O + nitrite


name: a cytidine in rRNA + S-adenosyl-L-methionine => a 5-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: Receptor FFAR3 binds carboxylates (Rattus norvegicus)


name: ADP(in) + diphosphate(out) => ADP(out) + diphosphate(in)


name: SIRT1,SIRT3 deacetylate FOXO3 (Homo sapiens)


name: ARSA removes sulfate from SM3 (Sus scrofa)


name: CLIP3 and CYLD bind TNF signaling complex (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: D-ribose 5-phosphate + uracil => H2O + psi-UMP


name: Caspase-mediated cleavage of gelsolin (Canis familiaris)


name: ST6GALNAC2 transfers sialic acid to Core 1 mucins (Gallus gallus)


name: Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton (Canis familiaris)


name: acetyl-CoA + CO2 + NADH => CoA + NAD(+) + pyruvate


name: RHOU auto-activates (Caenorhabditis elegans)


name: light-driven active monoatomic ion transmembrane transporter activity


name: USF1 is phosphorylated by p-MAPK14 (Bos taurus)


name: L-glutamate 5-semialdehyde + NADP(+) + phosphate => H(+) + L-glutamyl 5-phosphate + NADPH


name: dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2 <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+)


name: (1S,6R)-isopiperitenol + NAD(+) <=> (6R)-isopiperitenone + H(+) + NADH


name: a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base => a 1,3-diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Bos taurus)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: Activation of RAC1 by the PXN:CRK complex (Canis familiaris)


name: AMP + diphosphate + NADP(+) + picolinal => ATP + H(+) + NADPH + picolinate


name: 3-O-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + H(+) + UDP => 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: 3 O2 + quiannulatene + 3 reduced [NADPH--hemoprotein reductase] => 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + quiannulatate


name: ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)


name: 4-guanidinobutanoate + 2 H(+) + NADH => 4-guanidinobutanal + H2O + NAD(+)


name: Phosphorylation of UBF-1:rDNA Promoter (Danio rerio)


name: [phosphate](n) + GTP <=> [phosphate](n+1) + GDP


name: H(+)(in) + L-alanyl-L-proline(in) => H(+)(out) + L-alanyl-L-proline(out)


name: [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine => [calmodulin]-L-lysine + S-adenosyl-L-methionine


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Dictyostelium discoideum)


name: SEMA4D interacts with Plexin-B1:ErbB2 (Bos taurus)


name: cortisone + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxycortisone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetate + malonyl-CoA => acetyl-CoA + malonate


name: SPRY2 translocates to the plasma membrane (Bos taurus)


name: USP10 deubiquitinates SNX3, CFTR (Schizosaccharomyces pombe)


name: DRD2 antagonist drugs bind to DRD2 (Sus scrofa)


name: CYP3A4 monooxygenates ATVL to 4-OH-ATVL (Mus musculus)


name: A + butanoyl-CoA = (2E)-butenoyl-CoA + AH2


name: beta-alanine + pyruvate => 3-oxopropanoate + L-alanine


name: Activated TP receptor binds G-proten Gq (Homo sapiens)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Bos taurus)


name: GDP-alpha-D-rhamnose + NADP(+) <=> GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH


name: dADP(out) + H(+)(out) + phosphate(in) = dADP(in) + H(+)(in) + phosphate(out)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: a (2E,4E)-dienoyl-CoA + H(+) + NADPH <=> a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)


name: acrolein + hydrogen cyanide = (2S)-2-hydroxybut-3-enenitrile


name: OTUD3 deubiquitinates PTEN (Dictyostelium discoideum)


name: Activated FGFR4:p-FRS bind to PPTN11 (Bos taurus)


name: 5-hydroxyuridine(34) in tRNA + S-adenosyl-L-methionine = 5-methoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Gallus gallus)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Bos taurus)


name: 15alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => estrone + O2 + reduced [NADPH--hemoprotein reductase]


name: Glucosylation of collagen propeptide hydroxylysines (Homo sapiens)


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Homo sapiens)


name: cholate + NADP(+) = 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: H2O + N,N-dimethylformamide <=> dimethylamine + formate


name: Transhomodimerization of Nectins (Sus scrofa)


name: an acyl-CoA + L-cysteinyl-[protein] => an S-acyl-L-cysteinyl-[protein] + CoA


name: (2E,6E)-farnesyl diphosphate + H2O => 7-epi-alpha-eudesmol + diphosphate


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: Na(+)(out) + O-acetyl-(R)-carnitine(out) => Na(+)(in) + O-acetyl-(R)-carnitine(in)


name: 3'-phosphoadenylyl sulfate + 4-isopropylphenol => 4-isopropylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Mus musculus)


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Saccharomyces cerevisiae)


name: chloride(out) + formate(in) => chloride(in) + formate(out)


name: Active G alpha (z) binds RGS proteins (Bos taurus)


name: AMP + diphosphate + docosanoyl-CoA => ATP + CoA + docosanoate


name: TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (Gallus gallus)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Rattus norvegicus)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Sus scrofa)


name: Phosphorylated RHOU translocates to the endosome membrane (Homo sapiens)


name: a ceramide(in) + ATP + H2O <=> a ceramide(out) + ADP + H(+) + phosphate


name: (+)-epi-isozizaene + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> albaflavenone + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: ARFGAPs stimulate ARF GTPase activity (Rattus norvegicus)


name: acetyl-CoA + CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate => CMP-5'-(N-acetyl-N-hydroxy-3-aminopropyl)phosphonate + CoA


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Bos taurus)


name: Translocation of DFF to the nucleus (Sus scrofa)


name: protein tyrosine/threonine phosphatase activity


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Mus musculus)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Plasmodium falciparum)


name: ADP + ATP = adenosine 5'-tetraphosphate + AMP


name: (S)-malate(in) + citrate(out) = (S)-malate(out) + citrate(in)


name: RDH10,11 oxidise 11cROL to 11cRAL (Homo sapiens)


name: PPP1CC dephosphorylates PLK1 (Plasmodium falciparum)


name: T1R1/T1R3 dimer is the umami taste receptor (Canis familiaris)


name: (R)-pantothenate(out) + 2 Na(+)(out) => (R)-pantothenate(in) + 2 Na(+)(in)


name: chloride(out) + L-proline(out) + 2 Na(+)(out) => chloride(in) + L-proline(in) + 2 Na(+)(in)


name: glutamine + H2O => glutamate + NH4+ [GLS] (Drosophila melanogaster)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Canis familiaris)


name: a menaquinol + 2 O2 <=> a menaquinone + 2 H(+) + 2 superoxide


name: 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Mus musculus)


name: gamma-secretase cleaves the p75NTR transmembrane domain (Canis familiaris)


name: I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol (Sus scrofa)


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Homo sapiens)


name: ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate + H2O <=> acetate + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+)


name: itaconate + succinyl-CoA => itaconyl-CoA + succinate


name: MAOA inhibitors bind MAOA:FAD (Sus scrofa)


name: PDGF dimer binds two receptors simultaneously (Danio rerio)


name: a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H(+) = a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Danio rerio)


name: phycourobilin-L-cysteinyl(84)-[R-phycocyanin alpha-subunit] <=> (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[R-phycocyanin alpha-subunit]


name: STK11 (LKB1) phosphorylates NUAK1 (Mus musculus)


name: Beta-catenin binds SOX proteins (Caenorhabditis elegans)


name: Aquaporins passively transport water out of cells (Schizosaccharomyces pombe)


name: kainate receptor binds glutamate (Mus musculus)


name: STAT1 and STAT3 dimers translocate to the nucleus (Mus musculus)


name: (+)-O-methylkolavelool + H(+) + S-adenosyl-L-homocysteine => (+)-kolavelool + S-adenosyl-L-methionine


name: (R)-2-hydroxyglutaryl-CoA <=> (2E)-glutaconyl-CoA + H2O


name: ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA (Danio rerio)


name: D-glucose(out) + H(+)(out) => D-glucose(in) + H(+)(in)


name: glucose 1-dehydrogenase (NADP+) activity


name: PARG dePARylates PARP1,PARP2 (Xenopus tropicalis)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Gallus gallus)


name: (3R)-4-(dimethylamino)-3-hydroxybutanoate + methyl-Co(III)-[quaternary-amine-specific corrinoid protein] => (R)-carnitine + Co(I)-[quaternary-amine-specific corrinoid protein] + H(+)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Homo sapiens)


name: MMACHC decyanates CNCbl (Dictyostelium discoideum)


name: (E)-hept-2-enal + H2O + NADP(+) <=> (E)-hept-2-enoate + 2 H(+) + NADPH


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Mus musculus)


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Danio rerio)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Danio rerio)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Sus scrofa)


name: CXXC1 and WDR82 bind SET1B complex (Sus scrofa)


name: arseno-mycothiol + H2O => arsenate + mycothiol


name: 26-oxohexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + hexacosanedioate + oxidized [NADPH--hemoprotein reductase]


name: H2O + L-valine + NAD(+) <=> 3-methyl-2-oxobutanoate + H(+) + NADH + NH4(+)


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Rattus norvegicus)


name: 5-amino-1-(beta-D-ribosyl)imidazole + ATP <=> 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+)


name: Beta defensin 103 activates TLR1:TLR2 (Mus musculus)


name: Parenchymal atROL translocates to HSCs (Rattus norvegicus)


name: DPAn-3 maresins translocate from cytosol to extracellular region (Homo sapiens)


name: ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE (Bos taurus)


name: HDAC3 containing complexes deacetylate histone (Drosophila melanogaster)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GM1 (d18:1(4E)) + CMP + H(+)


name: H2O + N(2)-(4-aminobutanoyl)-L-lysine = 4-aminobutanoate + L-lysine


name: CDC42 GAPs stimulate CDC42 GTPase activity (Danio rerio)


name: S-adenosyl-L-methionine + taxifolin = H(+) + S-adenosyl-L-homocysteine + taxifolin 3'-methyl ether


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Xenopus tropicalis)


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Sus scrofa)


name: 2 Fe(2+) + 4 H2O + O2 <=> 6 H(+) + H2O2 + 2 iron(III) oxide-hydroxide


name: L-cystine(in) + Na(+)(in) => L-cystine(out) + Na(+)(out)


name: CoA + glutathione disulfide <=> CoA-glutathione + glutathione


name: H(+) + NADPH + O2 + oxytetracycline = 11a-hydroxy-oxytetracycline + H2O + NADP(+)


name: chromopyrrolate + H(+) + 2 H2O + NH4(+) => 2 2-iminio-3-(indol-3-yl)propanoate + H2O2


name: CLPXP degrades mitochondrial matrix proteins (Rattus norvegicus)


name: a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+) => a 3-oxosteroid + CO2 + NADPH


name: HGFAC cleaves pro-HGF to form HGF dimer (Sus scrofa)


name: ATP + choline => ADP + H(+) + phosphocholine


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Xenopus tropicalis)


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Rattus norvegicus)


name: CHOL translocates from lysosome membrane to ER membrane (Homo sapiens)


name: kaempferide + S-adenosyl-L-methionine <=> 7,4'-O-dimethylkaempferol + H(+) + S-adenosyl-L-homocysteine


name: Caspase-mediated cleavage of occludin (Danio rerio)


name: COASY phosphorylates DP-CoA (Dictyostelium discoideum)


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Dictyostelium discoideum)


name: 6-(hexadecan-2-yl)-4-hydroxy-pyran-2-one + 2 CO2 + 3 CoA => 2-methylhexadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: O2 + reduced [NADPH--hemoprotein reductase] + secologanin => 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + secoxyloganin


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Bos taurus)


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Rattus norvegicus)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Rattus norvegicus)


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Sus scrofa)


name: 28-norteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => 6-deoxo-28-norteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Caenorhabditis elegans)


name: (E)-caffeate + hydrocaffeoyl-CoA => (E)-caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)propanoate


name: 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Sus scrofa)


name: Formation of MCM2-7 complex (Danio rerio)


name: Formation of Elongin complex (Homo sapiens)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Homo sapiens)


name: 3-dehydro-L-gulonate + NADP(+) = 2,3-dioxo-L-gulonate + H(+) + NADPH


name: glycocholate(out) + n H(+)(out) => glycocholate(in) + n H(+)(in)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-ethanolamine => 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: RHOD binds effectors at the endosome membrane (Homo sapiens)


name: SCF:FBXL7 binds AURKA (Saccharomyces cerevisiae)


name: Collagen type II degradation by MMP15 (Caenorhabditis elegans)


name: H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine => pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine


name: LRRC16A binds F-actin capping protein (Mus musculus)


name: all-trans-13,14-dihydroretinal + H2O + NAD(+) <=> all-trans-13,14-dihydroretinoate + 2 H(+) + NADH


name: 4-aminobutanoate + H2O + O2 = H2O2 + NH4(+) + succinate semialdehyde


name: a ubiquinone + caffeine + H2O = 1,3,7-trimethylurate + a ubiquinol


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Xenopus tropicalis)


name: SUMOylation of NR1I2 with SUMO3 (Drosophila melanogaster)


name: Ubiquitinated AXIN is degraded by the proteasome (Bos taurus)


name: ACSF3 ligates CoA-SH to VLCFA (Sus scrofa)


name: GNLY binds the bacterial cell surface in the phagosome (Gallus gallus)


name: ethanol + o-quinone methide <=> hydroxyclavatol ethyl ether


name: (9Z)-hexadecenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA


name: Mitochondrial FPGS-1 transforms THF to THFPG (Saccharomyces cerevisiae)


name: RAD51B:RAD51C binds single-stranded DNA (Mus musculus)


name: MBTPS2 (S2P) cleaves CREB3L3 (Canis familiaris)


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Sus scrofa)


name: 7-cyano-7-carbaguanosine(15) in tRNA + NH4(+) <=> archaeosine(15) in tRNA


name: ABP1 binds SHANK proteins (Caenorhabditis elegans)


name: SLC12A3 binds SLC12A3 inhibitors (Drosophila melanogaster)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Saccharomyces cerevisiae)


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Rattus norvegicus)


name: DCC interacts with DIP13alpha (Bos taurus)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Xenopus tropicalis)


name: Activation of proMMP10 (Caenorhabditis elegans)


name: 2-demethylmenaquinol-8 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-octaprenyl diphosphate + H(+)


name: a ganglioside GD3 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GT3 (d18:1(4E)) + CMP + H(+)


name: formaldehyde + H2O + methylamine + NADP(+) => dimethylamine + H(+) + NADPH + O2


name: (2S)-2-methylbutanoyl-CoA + H(+) + malonyl-[ACP] <=> (4S)-4-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA


name: 3'-phosphoadenylyl sulfate + 3,3'-diiodo-L-thyronine <=> 3,3'-diiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: LIG3 ligates remaining SSBs in MMEJ (Rattus norvegicus)


name: BTNL2 binds activated T cells surface (Homo sapiens)


name: RET tyrosine phosphorylation (Sus scrofa)


name: HMGB1 binds LPS (Drosophila melanogaster)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Rattus norvegicus)


name: Cyclisation of GTP to precursor Z (Mus musculus)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Drosophila melanogaster)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Bos taurus)


name: SPHK2 phosphorylates sphingoid (Canis familiaris)


name: PKC autophosphorylates (Dictyostelium discoideum)


name: Thrombin-activated PARs binds G-protein Gq (Xenopus tropicalis)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)


name: 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine => 7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA


name: Addition of Tegument to HCMV Nucleocapsid C (Homo sapiens)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Sus scrofa)


name: NADPH transfers electrons to FDXR (Caenorhabditis elegans)


name: Amyloid precursor proteins form ordered fibrils (Homo sapiens)


name: mRNP complex dissociates from cytosolic face of NPC (Bos taurus)


name: 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate = 7,8-dihydroneopterin 3'-phosphate + H2O


name: USP43 binds ISG:K164,ISG:K168-PCNA (Bos taurus)


name: FKBP5 gene expression is inhibited by MECP2 (Homo sapiens)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Sus scrofa)


name: 12-methyltridecanoate + ATP + CoA = 12-methyltridecanoyl-CoA + AMP + diphosphate


name: AH2 + L-isoleucyl-[protein] + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + methylcyclopropylglycine-[protein]


name: BESTs transport cytosolic Cl- to extracellular region (Xenopus tropicalis)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Bos taurus)


name: 3-oxododecanoyl-CoA + H2O <=> 3-oxododecanoate + CoA + H(+)


name: Tetrastatin binds integrin alphaVbeta3 (Sus scrofa)


name: RHOV binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: Activation of Calcineurin (Homo sapiens)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Gallus gallus)


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] <=> 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Homo sapiens)


name: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine


name: p75NTR and RHOA-GDI interact (Mus musculus)


name: calcitriol 25-O-(beta-D-glucuronide) + H(+) + UDP => calcitriol + UDP-alpha-D-glucuronate


name: H(+)(out) + 2 nitrate(out) = H(+)(in) + 2 nitrate(in)


name: DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function (Mus musculus)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Mus musculus)


name: Cohesin binds PDS5 and WAPAL (Schizosaccharomyces pombe)


name: (9Z)-octadecenoyl-CoA + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + octadecanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2-oxobutanoate + CO2 + NADH => (2R,3S)-3-methylmalate + NAD(+)


name: COPI vesicle uncoating at the ER (Drosophila melanogaster)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Bos taurus)


name: RHOA binds effectors at the plasma membrane (Schizosaccharomyces pombe)


name: dimethylmaleate + H2O => (2R,3S)-2,3-dimethylmalate


name: USP13 and OTUD3 deubiquitinate PTEN (Drosophila melanogaster)


name: Conversion of glyoxylate to oxalate (Caenorhabditis elegans)


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Homo sapiens)


name: 2-nitrotoluene + NADH + O2 = 3-methylcatechol + NAD(+) + nitrite


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Bos taurus)


name: SUMOylation of RXRA with SUMO1 (Mus musculus)


name: H(+) + phosphate + presqualene phosphate => H2O + presqualene diphosphate


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Danio rerio)


name: Alpha1-Microglobulin binds heme (Gallus gallus)


name: 2-aminomuconate 6-semialdehyde => 2-aminophenol + O2


name: AH2 + C(3,19),S(21)-[cypemycin](1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide + CO2 + hydrogen sulfide => [cypemycin](1-18)-L-Cys-L-Leu-L-Val-L-Cys + A


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Mus musculus)


name: H2O + N-(9Z-octadecenoyl)-taurine <=> (9Z)-octadecenoate + taurine


name: (E)-sinapate + H(+) + S-adenosyl-L-homocysteine => (E)-5-hydroxyferulate + S-adenosyl-L-methionine


name: MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Rattus norvegicus)


name: 27-hydroxysterol binds ESR1, ESR2 (Danio rerio)


name: benzoyl-CoA + 2 H(+) + 3 malonyl-CoA => 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA


name: glyoxylate + L-2-aminoadipate = 2-oxoadipate + glycine


name: Follicle-stimulating hormone receptor can bind FSH (Mus musculus)


name: 2 fonsecin B + H(+) + NADPH + O2 => bifonsecin B + 2 H2O + NADP(+)


name: CYP3A4,5 hydroxylates AFB1 to AFQ1 (Rattus norvegicus)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Danio rerio)


name: (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + 2 CO2 + H2O + succinate


name: Kinesin-5 is a homotetramer (Bos taurus)


name: RP2:ARL3:GDP:UNC119B dissociates (Danio rerio)


name: eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Canis familiaris)


name: PPARG binds PPARG agonists (Drosophila melanogaster)


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Dictyostelium discoideum)


name: 2-dehydro-3-deoxy-D-arabinonate => glycolaldehyde + pyruvate


name: a cytidine in mRNA + S-adenosyl-L-methionine => a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: 4-nitrocatechol + H(+) + NAD(+) + nitrite => 1,3-dinitrobenzene + NADH + O2


name: Formation of peptide loading complex (PLC) (Bos taurus)


name: a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Dictyostelium discoideum)


name: Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)


name: a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + H(+) + NADPH + O2 <=> a (Z)-omega-(methylsulfinyl)-alkyl-glucosinolate + H2O + NADP(+)


name: Autophosphorylation of SRC (Caenorhabditis elegans)


name: (6E)-8-hydroxygeranial + NAD(+) <=> (6E)-8-oxogeranial + H(+) + NADH


name: SCF(SKP2) complex binds RUNX2 (Canis familiaris)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(36-hydroxyhexatriacontenoyl)-sphing-4-enine = a diacylglycerol + an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontenoyl)-sphing-4-enine


name: biotinate sulfoxide + H(+) + NADH => biotin + H2O + NAD(+)


name: FOXO1,FOXO3 binds CAV1 gene promoter (Homo sapiens)


name: D-glyceraldehyde 3-phosphate + L-arginine = H(+) + N(2)-(2-carboxyethyl)-L-arginine + phosphate


name: (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+) => (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADPH + O2


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Sus scrofa)


name: PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Xenopus tropicalis)


name: 2,6,10,14-tetramethylpentadecanal + formyl-CoA => 2-hydroxyphytanoyl-CoA


name: RNA cap trimethylguanosine synthase activity


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Drosophila melanogaster)


name: 6 ATP <=> cyclic hexaadenylate + 6 diphosphate


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Drosophila melanogaster)


name: an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose <=> a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: TNF-alpha inhibitors bind to TNF(1-233) trimer (Rattus norvegicus)


name: Connexin synthesis (generic) (Canis familiaris)


name: (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate <=> 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O


name: Nuclear DUSPs dephosphorylate MAPKs (Mus musculus)


name: steviolbioside glucosyltransferase activity (stevioside forming)


name: PIAS1 SUMOylates SAFB with SUMO1 (Mus musculus)


name: H2O + N(5)-hydroxy-L-ornithine + NADP(+) => L-ornithine + NADPH + O2


name: Ca impermeable AMPA receptor ligand binding (Caenorhabditis elegans)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Caenorhabditis elegans)


name: L-valine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-2-methylpropanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Mus musculus)


name: anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) <=> 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH


name: AVPR1A,2 bind AVPR antagonists (Gallus gallus)


name: trans-Golgi Network Lysosomal Vesicle Scission (Danio rerio)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2) => beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2)


name: luteolin + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-beta-D-glucuronide + UDP


name: 28-nortyphasterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 6alpha-hydroxy-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase]


name: D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate + H(+) + NADPH


name: DOCK180:ELMO binds CRK (Xenopus tropicalis)


name: a plastoquinone + (n+1) H(+)(in) + NADH <=> a plastoquinol + n H(+)(out) + NAD(+)


name: H(+) + linamarin + UDP => 2-hydroxy-2-methylpropanenitrile + UDP-alpha-D-glucose


name: gamma-tocopherol + S-adenosyl-L-methionine = (+)-alpha-tocopherol + H(+) + S-adenosyl-L-homocysteine


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Sus scrofa)


name: Formation of CDK4/6:CCND complexes (Homo sapiens)


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 O2 => 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + 2 succinate


name: glutathione disulfide + 2 L-homocysteine => 2 glutathione + L,L-homocystine


name: PP2A-B56 dephosphorylates centromeric cohesin (Homo sapiens)


name: 14-3-3 Binds p-S237-TBC1D1 (Homo sapiens)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Homo sapiens)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)


name: AS3MT transfers CH3 from AdoMet to arsenite(3-) (Bos taurus)


name: (2R)-2,3-dihydroxy-3-methylbutanoate => 3-methyl-2-oxobutanoate + H2O


name: 2 CO2 + reduced 2[4Fe-4S]-[ferredoxin] => oxalate + oxidized 2[4Fe-4S]-[ferredoxin]


name: NTPDase1 hydrolyzes nucleoside diphosphates (Rattus norvegicus)


name: Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 (Danio rerio)


name: S-adenosyl-L-methionine + theobromine = caffeine + H(+) + S-adenosyl-L-homocysteine


name: Formation of MCM2-7 complex (Homo sapiens)


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Bos taurus)


name: 3-hydroxyanthranilate + O2 => H(+) + H2O + quinolinate


name: a ribonucleoside 3'-phosphate + H2O => a ribonucleoside + phosphate


name: SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Mus musculus)


name: Formation of the 43S pre-initiation complex (Homo sapiens)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Sus scrofa)


name: PGM2:Mg2+ isomerises R1P to R5P (Bos taurus)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Mus musculus)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Rattus norvegicus)


name: Expression of Erythropoietin (EPO) (Homo sapiens)


name: p-S215 FOXO1 binds RAG gene (Homo sapiens)


name: CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate (Canis familiaris)


name: H2O + oxaloacetate + propanoyl-CoA = (2S,3S)-2-methylcitrate + CoA + H(+)


name: dimethylallyl diphosphate + leachianone G <=> diphosphate + sophoraflavanone G


name: 5-hydroxymethylfurfural + O2 <=> 2,5-diformylfuran + H2O2


name: EGFR activates PLC-gamma1 by phosphorylation (Danio rerio)


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Dictyostelium discoideum)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Mus musculus)


name: orexigenic neuropeptide QRFP receptor binding


name: Interaction of Tie2 and Shp2 (Xenopus tropicalis)


name: SRC phosphorylates PTK2 (Canis familiaris)


name: RHOG translocates to the ER membrane (Gallus gallus)


name: alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose => alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: Defective SLC35D1 does not transport UDP-GlcA, UDPGlcNAc (Homo sapiens)


name: ent-isokaurene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = ent-isokaurene-2beta,3beta-diol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + H(+) + NADPH + O2 = H2O + NADP(+) + semiviriditoxin


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 19-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Canis familiaris)


name: Aquaporins passively transport urea out of cells (Schizosaccharomyces pombe)


name: cholate + NADP(+) <=> 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH


name: (3R)-3-isocyanylbutanoate + ATP + holo-[ACP] = (3R)-3-isocyanylbutanoyl-[ACP] + AMP + diphosphate


name: D-alanine [D-alanyl carrier protein] ligase activity


name: CTP + N-acetyl-D-glucosamine = CDP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: L-altrarate => 5-dehydro-4-deoxy-D-glucarate + H2O


name: 2,3-dihydrobiochanin A + NADP(+) <=> biochanin A + 2 H(+) + NADPH


name: an N-(fatty acyl)-L-tryptophan + H2O => a fatty acid + L-tryptophan


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Saccharomyces cerevisiae)


name: PE is methylated to PC by PEMT (Canis familiaris)


name: PTPN1 dephosphorylates PTK6 (Xenopus tropicalis)


name: N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Danio rerio)


name: (2E,6E,10E)-geranylgeranyl diphosphate = diphosphate + rhizathalene A


name: B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)


name: 3-aminobutan-2-ol + H2O + NAD(+) = acetoin + H(+) + NADH + NH4(+)


name: CO2 + norspermidine => carboxynorspermidine + H(+)


name: RAS:GTP binds RAL GDS proteins (Caenorhabditis elegans)


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Homo sapiens)


name: RHOD GAPs stimulate RHOD GTPase activity (Xenopus tropicalis)


name: (2E)-butenoyl-CoA + L-lysyl-[protein] <=> CoA + H(+) + N(6)-(2E)-butenoyl-L-lysyl-[protein]


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate


name: ectocarpin D => (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + H2O


name: (2R)-heptan-2-amine + H2O + NAD(+) => H(+) + heptan-2-one + NADH + NH4(+)


name: n H(+)(out) + L-histidine(out) => n H(+)(in) + L-histidine(in)


name: 4-hydroxy-N-methyltryptamine 4-phosphate + H(+) + S-adenosyl-L-homocysteine => 4-hydoxytryptamine 4-phosphate + S-adenosyl-L-methionine


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA <=> 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: SLC50A1 transports Glc from cytosol to extracellular region (Dictyostelium discoideum)


name: Activation of Calcineurin (Plasmodium falciparum)


name: hexadecanal + NADP(+) = (2E)-hexadecenal + H(+) + NADPH


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Canis familiaris)


name: RNA polymerase II CTD heptapeptide repeat P3 isomerase activity


name: Docking of Mature Histone mRNA complex:TAP at the NPC (Canis familiaris)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Xenopus tropicalis)


name: 3,4-dihydroxyphenylacetate + H(+) + NADH + O2 <=> 2,4,5-trihydroxyphenylacetate + H2O + NAD(+)


name: H(+) + S-sulfanyl-L-cysteinyl-[SoxY protein] + sulfate => H2O + S-sulfosulfanyl-L-cysteinyl-[SoxY protein]


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Caenorhabditis elegans)


name: E2F6:TFDP1 binds to MGA:MAX (Drosophila melanogaster)


name: methylazoxymethanol + UDP-alpha-D-glucose => cycasin + H(+) + UDP


name: PP6-PPP6R3 dephosphorylates TERF2 (Sus scrofa)


name: (E)-4-coumarate + UDP-alpha-D-glucose <=> 4-O-(beta-D-glucosyl)-trans-4-coumarate + H(+) + UDP


name: 24-methylenecholesterol + UDP-alpha-D-glucose <=> 24-methylene cholesteryl beta-D-glucoside + H(+) + UDP


name: S-adenosyl-L-methionine + thiocyanate <=> methyl thiocyanate + S-adenosyl-L-homocysteine


name: (4Z,15Z)-bilirubin IXalpha + 4 AH2 => 4 A + urobilinogen


name: ALD3A1 oxidises 4HPCP to CXPA (Canis familiaris)


name: H(+) + NADH + naphthalene + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+)


name: protocatechuate 3,4-dioxygenase type II activity


name: HYKK phosphorylates 5HLYS (Homo sapiens)


name: B4GALTs transfer Gal to the keratan chain (Drosophila melanogaster)


name: glutamate uptake by astrocytes (Danio rerio)


name: Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 (Homo sapiens)


name: ATP + CoA + IC-asc-C7 <=> AMP + diphosphate + IC-asc-C7-CoA


name: 2,5-dihydroxypyridine + O2 <=> H(+) + N-formylmaleamate


name: guanosine(2922) in 27S pre-rRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(2922) in 27S pre-rRNA + H(+) + S-adenosyl-L-homocysteine


name: 5-epi-alpha-selinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (2E)-decenoyl-CoA + H2O = 3-hydroxydecanoyl-CoA


name: (R)-lavandulyl diphosphate + diphosphate => 2 dimethylallyl diphosphate


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Danio rerio)


name: MLCL is acylated to CL by LCLAT1 (ER) (Sus scrofa)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Homo sapiens)


name: LIPH, I hydrolyse PA to 2-acyl LPA (Bos taurus)


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Sus scrofa)


name: GCHFR binds to GCH1 and negatively regulates its activity (Bos taurus)


name: glyoxylate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Homo sapiens)


name: D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H(+) + H2O2


name: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity


name: 2 H(+) + MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-penta-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 tRNA(Gly) => 2 glycyl-tRNA(Gly) + MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-tri-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Gallus gallus)


name: a ganglioside GA1 + UDP-N-acetyl-alpha-D-glucosamine => a ganglioside beta-DGlcNAc-(1->6)-GA1 + H(+) + UDP


name: diphosphate + P(1),P(4)-bis(5'-guanosyl) tetraphosphate => 2 GTP + H(+)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Rattus norvegicus)


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Drosophila melanogaster)


name: BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Canis familiaris)


name: GNE phosphorylates ManNAc to ManNAc-6-P (Rattus norvegicus)


name: CMP-N-acetyl-beta-neuraminate + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] => 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+)


name: dihydrosanguinarine + O2 + reduced [NADPH--hemoprotein reductase] => 10-hydroxydihydrosanguinarine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoate + glycerol + H(+) => (9Z-octadecenoyl)-glycerol + H2O


name: (R)-mevalonate + CoA + 2 NADP(+) <=> (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH


name: Src phosphorylate WASP,N-WASP (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine <=> 3,3',4',5,7-pentahydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: H(+) + menaquinone-8 + NADPH = menaquinol-8 + NADP(+)


name: ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate (Gallus gallus)


name: Syk activation leads to SLP-76 activation (Homo sapiens)


name: N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + O2 + reduced [NADPH--hemoprotein reductase] = 2-oxo-N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-leucine = H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-leucine


name: a 3'-end uridylyl-uridine-RNA => a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine


name: Gi,Go Heterotrimeric G-protein complex dissociates (Danio rerio)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O = a 5'-end phospho-guanosine in mRNA + 2 H(+) + N(7)-methyl-GDP


name: PIPOX oxidises PPCA to P6C (Caenorhabditis elegans)


name: (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] <=> (2S)-dihydrotricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: KLK5 cleaves and activates CELA2 (Rattus norvegicus)


name: NEDD4L ubiquitinates SMAD2/3 (Bos taurus)


name: Cleavage of thymine by MBD4 glycosylase (Mus musculus)


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Canis familiaris)


name: USP8 deubiquitinates LRIG1 (Rattus norvegicus)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Xenopus tropicalis)


name: RHAG transports CO2 from cytosol to extracellular region (Danio rerio)


name: VRI replaces PDP1 as binder to Clk and cry genes (Drosophila melanogaster)


name: high-affinity L-glutamate transmembrane transporter activity


name: (2E)-geranyl diphosphate = (1R,5R)-alpha-pinene + diphosphate


name: WLS:WNT complex is internalized for maturation into exosomes (Gallus gallus)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Rattus norvegicus)


name: a (1E)-1-aci-nitro-omega-(methylsulfanyl)alkane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => an (E)-omega-(methylsulfanyl)-alkanal oxime + O2 + reduced [NADPH--hemoprotein reductase]


name: (6S)-5,6,7,8-tetrahydrofolate + L-serine => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O


name: (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+) = H(+) + NADH + naphthalene-1,2-diol


name: a 5,6-dihydrouridine in RNA + NADP(+) <=> a uridine in RNA + H(+) + NADPH


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Schizosaccharomyces pombe)


name: E2F6.com-1 complex binds the E2F1 gene promoter (Homo sapiens)


name: L-aspartate(in) + succinate(out) => L-aspartate(out) + succinate(in)


name: D-xylobiono-1,5-lactone + H2O2 => D-xylobiose + O2


name: ABCF1 binds EIF2 (Dictyostelium discoideum)


name: 2-oxoglutarate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] <=> CO2 + N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase]


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA => 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Gallus gallus)


name: Apelin receptor binds to apelin (Gallus gallus)


name: 2-oxoglutarate + D-kanosamine 6-phosphate => 3-dehydro-D-glucose 6-phosphate + L-glutamate


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Drosophila melanogaster)


name: L-arginyl-[protein] + NAD(+) => H(+) + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide


name: 2 chloride(out) + glycine betaine(out) + 3 Na(+)(out) => 2 chloride(in) + glycine betaine(in) + 3 Na(+)(in)


name: 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: S-adenosyl-L-methionine + uridine(2552) in 23S rRNA <=> 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: MAOA:FAD deaminates DA to DOPAC (Gallus gallus)


name: 1-O-decyl-(9Z)-octadecenoate + CoA => (9Z)-octadecenoyl-CoA + decan-1-ol


name: BLT receptors can bind LTB4 (Drosophila melanogaster)


name: cytidine(2278) in 25S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(2278) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + hexanal + NAD(+) => 2 H(+) + hexanoate + NADH


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Homo sapiens)


name: ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate => ATP + L-glutamate + L-propargylglycine


name: (5R)-5-hydroxy-L-lysine + GTP => (5R)-5-phosphooxy-L-lysine + GDP + H(+)


name: 2-hydroxydodecanoate + H2O2 => 2,3-dihydroxydodecanoate + H2O


name: CEBPB and phospho-STAT3 bind the promoter of the MYC gene (Homo sapiens)


name: 2-cis-(+)-abscisate + O2 + reduced [NADPH--hemoprotein reductase] <=> (+)-8'-hydroxyabscisate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Gallus gallus)


name: Transfer of NEDD8 to AcM-UBE2F (Rattus norvegicus)


name: 2-oxoglutarate + jasmonate + O2 <=> (1R,2R)-12-hydroxyjasmonate + CO2 + succinate


name: RRAGA,B exchanges GDP for GTP (Schizosaccharomyces pombe)


name: ethane-1-sulfonate + FMNH2 + O2 => acetaldehyde + FMN + 2 H(+) + H2O + sulfite


name: Autophosphorylation and activation of CAMK2 (Homo sapiens)


name: 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + AH2 = (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + A


name: fumarate(out) + 3 Na(+)(out) => fumarate(in) + 3 Na(+)(in)


name: 2 Na(+)(out) + nitrate(out) => 2 Na(+)(in) + nitrate(in)


name: Initiation of HCMV DNA Replication (Homo sapiens)


name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate (Homo sapiens)


name: 2 H(+) + O2 + pentalen-13-ol + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al


name: CoA + H(+) + N(6)-acetyl-L-lysyl-[protein] => acetyl-CoA + L-lysyl-[protein]


name: CHEK1 phosphorylates RAD51 (Schizosaccharomyces pombe)


name: Activated FMNL3 binds G-actin (Homo sapiens)


name: a D-guloside + NAD(+) <=> a 3-dehydro-D-guloside + H(+) + NADH


name: 9-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Phosphorylation of nephrin by FYN (Homo sapiens)


name: ABCG4 may mediate cholesterol efflux (Canis familiaris)


name: acetyl-CoA + 22 H(+) + 11 malonyl-CoA + 12 NADPH + S-adenosyl-L-methionine = 12 CO2 + 12 CoA + 8 H2O + 12 NADP(+) + S-adenosyl-L-homocysteine + soppiline B


name: a 1-acyl-sn-glycero-3-phosphate + hexadecanoyl-CoA <=> 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: 5alpha-cholesta-7,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 7-dehydrodesmosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Homo sapiens)


name: a sphingomyelin + H2O => an N-acylsphing-4-enine + H(+) + phosphocholine


name: a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP => a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine


name: (S)-3-hydroxy-2-methylpropanoate + CoA + H(+) => (S)-3-hydroxyisobutanoyl-CoA + H2O


name: US11:HLA binds DERL1:TMEM129:Ub:UBE2J2,UBE2K:VIMP:VCP (Homo sapiens)


name: FMO3:FAD N-oxidises TMA to TMAO (Sus scrofa)


name: type III transforming growth factor beta receptor binding


name: ARSC hydrolyzes steroid sulfates (Bos taurus)


name: 3-methylbutanoate + ATP + CoA => 3-methylbutanoyl-CoA + AMP + diphosphate


name: H2O + NAD(+) + NH4(+) => 2 H(+) + hydroxylamine + NADH


name: (3S)-hydroxydecanedioyl-CoA + NAD(+) = 3-oxodecanedioyl-CoA + H(+) + NADH


name: TFAP2C homodimer binds MYC and KDM5B (Drosophila melanogaster)


name: H(+) + malonyl-[ACP] + pentanoyl-CoA <=> 3-oxoheptanoyl-[ACP] + CO2 + CoA


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Sus scrofa)


name: PRKCB gene expression is stimulated by RUNX1 (Homo sapiens)


name: CREB3L3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Canis familiaris)


name: a 2-acyl-sn-glycero-3-phosphocholine + H2O => a 2-acyl-sn-glycerol 3-phosphate + choline + H(+)


name: asperterpenoid C + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => asperterpenoid A + O2 + reduced [NADPH--hemoprotein reductase]


name: salicyl alcohol + UDP-alpha-D-glucose <=> H(+) + salicin + UDP


name: 2-oxoglutarate + codeine + O2 => CO2 + formaldehyde + morphine + succinate


name: CHEK2 phosphorylates TP53 (Drosophila melanogaster)


name: CHOL translocates from lysosome membrane to ER membrane (Rattus norvegicus)


name: trans-Golgi Network Lysosomal Vesicle Scission (Bos taurus)


name: GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H(+)


name: ATP + L-seryl-[tyrosine-3-monooxygenase] <=> ADP + H(+) + O-phospho-L-seryl-[tyrosine-3-monooxygenase]


name: AcK685 pY705,S727 STAT3 binds the MIR21 gene (Homo sapiens)


name: an S-prenyl-L-cysteine + H2O + O2 => a prenal + H2O2 + L-cysteine


name: PLG(20-810) binds anti-fibrinolytics (Rattus norvegicus)


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Xenopus tropicalis)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Schizosaccharomyces pombe)


name: Growth hormone binds the growth hormone receptor (Danio rerio)


name: Defective HYAL1 does not hydrolyse (HA)50 (Homo sapiens)


name: deoxycholoyl-CoA + ursodeoxycholate <=> deoxycholate + ursodeoxycholoyl-CoA


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Danio rerio)


name: DEGS1 dehydrogenates dihydroceramide (Drosophila melanogaster)


name: PRC2 trimethylates histone H3 at lysine-27 (Gallus gallus)


name: Myoglobin:oxygen dissociates (Canis familiaris)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Drosophila melanogaster)


name: a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+) = a very-long-chain 3-oxoacyl-CoA + H(+) + NADH


name: factor XII -> factor XIIa (Mus musculus)


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = corticosterone + H2O + 2 oxidized [adrenodoxin]


name: 2 L-ascorbate + N-tetradecanoylglycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-tetradecanoyl-(2S)-hydroxyglycine


name: 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Drosophila melanogaster)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Xenopus tropicalis)


name: eicosanoate + glycine <=> H2O + N-eicosanoylglycinate


name: H(+) + menaquinol-8 + trimethylamine N-oxide = H2O + menaquinone-8 + trimethylamine


name: a glycerophospholipid(in) + ATP + H2O <=> a glycerophospholipid(out) + ADP + H(+) + phosphate


name: Formation of the SET1B complex (Homo sapiens)


name: SCF-FBXL7 ubiquitinates AURKA (Danio rerio)


name: Inhibition of JAK kinase activity by SOCS1/3 (Homo sapiens)


name: (2Z,6E)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate


name: Caspase-6 translocates to the nucleus (Bos taurus)


name: UDP-alpha-D-glucuronate(in) + UDP-N-acetyl-alpha-D-galactosamine(out) => UDP-alpha-D-glucuronate(out) + UDP-N-acetyl-alpha-D-galactosamine(in)


name: glycine betaine + H(+) + NADH + O2 => glyoxylate + H2O + NAD(+) + trimethylamine


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Sus scrofa)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Xenopus tropicalis)


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + phosphate => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + NH4(+)


name: 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+) <=> 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + CO2


name: Activated FGFR4 binds PLCG1 (Sus scrofa)


name: N(pros)-phospho-L-histidyl-[protein](out) + sucrose => L-histidyl-[protein] + sucrose 6(G)-phosphate(in)


name: hapalindole U => 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole


name: (25R)-3beta-hydroxycholest-5-en-7-one-26-al + H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3beta-hydroxycholest-5-en-7-one-26-oate + H2O + 2 oxidized [adrenodoxin]


name: 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + H(+) + phosphate => 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H2O


name: PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Canis familiaris)


name: H2O + trans-2,3-epoxysuccinate <=> (2R,3S)-tartrate


name: morphine + NAD(+) = H(+) + morphinone + NADH


name: coenzyme B + coenzyme M + methanophenazine => coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine


name: a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine <=> a 1,3-diacylglycerol + an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine


name: Keratin filaments bind cell-cell adhesion complexes (Gallus gallus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 5-oxopentanoate + H(+) => 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O


name: D-glucono-1,5-lactone + H(+) + NADH => D-glucose + NAD(+)


name: sialate:monoatomic cation symporter activity


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Canis familiaris)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate = (1R,2R,3R)-prephytoene diphosphate + diphosphate


name: TNF-alpha inhibitors bind to soluble TNF trimer (Rattus norvegicus)


name: PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins (Bos taurus)


name: (1R,4R,5R)-5-hydroxycamphor + NAD(+) = (1R,4R)-bornane-2,5-dione + H(+) + NADH


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe (Sus scrofa)


name: Phosphorylation of PLC-gamma1 (Mus musculus)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Sus scrofa)


name: L-isoleucine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-isoleucine + oxidized [NADPH--hemoprotein reductase]


name: large conductance calcium-activated potassium channel activity


name: protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity


name: DCC interacts with DIP13alpha (Mus musculus)


name: GUCYs converts GTP to cGMP (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: CHPF,CHSY3 transfer GalNAc to chondroitin (Bos taurus)


name: ATP + coproporphyrinogen III(in) + H2O => ADP + coproporphyrinogen III(out) + H(+) + phosphate


name: PRKACA phosphorylates TNNI3 (Danio rerio)


name: 3'-phosphoadenylyl sulfate + deoxycholate <=> 3alpha-sulfodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Drosophila melanogaster)


name: H2O + sucrose 6(F)-phosphate <=> beta-D-fructose + beta-D-glucose 6-phosphate


name: an N-(fatty acyl)-L-tyrosine + H2O <=> a fatty acid + L-tyrosine


name: oleate transmembrane transporter activity


name: H(+) + H2O + lochnericine + oxidized [NADPH--hemoprotein reductase] => (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase]


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Danio rerio)


name: uracil transmembrane transporter activity


name: SAR1 Activation And Membrane Binding (Mus musculus)


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Sus scrofa)


name: p-Y705-STAT3, p-Y641-STAT6 dimerise (Xenopus tropicalis)


name: 9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone


name: H2O + N-acetylisatin => N-acetylindoxyl + O2


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Bos taurus)


name: 1-tetradecanoylglycerol + H2O <=> glycerol + H(+) + tetradecanoate


name: (13Z)-docosenoyl-CoA + (4R)-hydroxysphinganine = CoA + H(+) + N-(13Z-docosenoyl)-4R-hydroxysphinganine


name: galactitol + NADP(+) = D-galactose + H(+) + NADPH


name: ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate


name: The bound receptor dimerizes (Canis familiaris)


name: HEXA cleaves the terminal GalNAc from small HA fragments (Drosophila melanogaster)


name: (1S,2R,4S)-neodihydrocarveol + NAD(+) = (1S,4S)-dihydrocarvone + H(+) + NADH


name: 4-aminobenzoate + 2 H(+) + NADH + O2 => 4-aminophenol + CO2 + H2O + NAD(+)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Caenorhabditis elegans)


name: (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase] <=> 3beta-hydroxycostunolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of RAD52 heptameric ring structure complexes (Bos taurus)


name: SLC25A10 mediates exchange of malate and phosphate (Rattus norvegicus)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate = (+)-beta-selinene + diphosphate


name: PDE12 cleaves 2'-5' oligoadenylates  (Canis familiaris)


name: acetyl-CoA + cortisol => CoA + cortisol 21-acetate


name: Phosphorylated STAT92E dimer is dephosphorylated by PTP61F isoform 2 (Drosophila melanogaster)


name: cAMP induces dissociation of inactive PKA tetramers (Xenopus tropicalis)


name: p-PKR dimer phosphorylates SNCA (Homo sapiens)


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Mus musculus)


name: beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-seryl-[protein] => H2O + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein]


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: NAD-dependent protein lysine deacetylase activity


name: [beta-adrenergic receptor] + ATP = [beta-adrenergic receptor]-phosphate + ADP + H(+)


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 = CO2 + cylindrospermopsin + succinate


name: 1D-myo-inositol 4-phosphate + H2O => myo-inositol + phosphate


name: glycyl-[protein] + reduced [flavodoxin] + S-adenosyl-L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[protein] + H(+) + L-methionine + semiquinone [flavodoxin]


name: MASTL phosphorylates ENSA (Canis familiaris)


name: Disassembly of COPII coated vesicle (Canis familiaris)


name: TCR binds self-lipid-based antigen via CD1 (Mus musculus)


name: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate => 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O


name: CYP1A2 hydroxylates AFB1 to AFM1 (Danio rerio)


name: (S)-malate + NAD(+) => CO2 + NADH + pyruvate


name: CDC42 and PIP2 bind WASL, activating it (Gallus gallus)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane (Xenopus tropicalis)


name: CO2 + L-tyrosine + NADPH => L-arogenate + NADP(+)


name: 2 a Fe(II)-siderophore + H(+) + NAD(+) => 2 a Fe(III)-siderophore + NADH


name: cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 4-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Association of procollagen type XII (Gallus gallus)


name: ADRB2 in ADRB2:GRK complex is phosphorylated (Bos taurus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Drosophila melanogaster)


name: hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Sus scrofa)


name: PDPK1 phosphorylates AKT1 E17K mutant (Homo sapiens)


name: (S)-carnitinyl-CoA + ADP + phosphate => (S)-carnitine + ATP + CoA


name: KCTD1 binds TFAP2 homo- and heterodimers (Bos taurus)


name: 6-hydroxyhexanoate + NADP(+) => 6-oxohexanoate + H(+) + NADPH


name: 3-methylxanthine + H(+) + NADPH + O2 = formaldehyde + H2O + NADP(+) + xanthine


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: IL37 binds 2x(CASP1(120-197):CASP1(317-404)) (Xenopus tropicalis)


name: H(+) + NADPH + naphthalene-1,2-diol => (1S,2S)-1,2-dihydronaphthalene-1,2-diol + NADP(+)


name: UBA1 adenylates ubiquitin in the cytosol (Gallus gallus)


name: WLS binds WNT ligands in the Golgi (Caenorhabditis elegans)


name: a ganglioside GT1a + CMP + H(+) => a ganglioside GD1a + CMP-N-acetyl-beta-neuraminate


name: Formation of Classical C3 convertase (C4b:C2a complex) (Bos taurus)


name: 2-iminoacetate + H2O => glyoxylate + NH4(+)


name: (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Mus musculus)


name: ATP + L-seryl-[tyrosine-3-monooxygenase] = ADP + H(+) + O-phospho-L-seryl-[tyrosine-3-monooxygenase]


name: 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] <=> 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Soluble PROCR binds PRTN3:CD177 (Sus scrofa)


name: (2E)-glutaconyl-CoA + H2O => (S)-3-hydroxyglutaryl-CoA


name: D-ribono-1,4-lactone + H(+) + NADH => D-ribose + NAD(+)


name: 1'-[1-acyl-2-(9-hydroxy-(10E,12Z)-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1,2-diacyl-sn-glycero-3-phospho]-glycerol + H2O => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + 9-hydroxy-(10E,12Z)-octadecadienoate + H(+)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Saccharomyces cerevisiae)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Canis familiaris)


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Rattus norvegicus)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Sus scrofa)


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP-beta-L-colitose <=> alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP + H(+)


name: CaMKK autophosphorylates in the nucleus (Rattus norvegicus)


name: 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + S-adenosyl-L-methionine => 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Sus scrofa)


name: Nuclear translocation of p38 MAPK (Drosophila melanogaster)


name: PLK1 binds phosphorylated condensin II complex (Gallus gallus)


name: coenzyme A transmembrane transporter activity


name: Conversion of Glycerol to Glycerol-3-phosphate (Caenorhabditis elegans)


name: acetate + ATP + holo-[citrate lyase ACP] => acetyl-[citrate lyase ACP] + AMP + diphosphate


name: ALDH3A2-2 oxidizes pristanal to pristanate (Dictyostelium discoideum)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(32-hydroxydotriacontanoyl)-sphing-4-enine <=> a diacylglycerol + N-(32-(9Z,12Z-octadecadienoyloxy)-dotricontanoyl)-sphing-4-enine


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA <=> 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-choline => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: glycine + L-methionine => glycyl-L-methionine + H2O


name: (2E)-geranyl diphosphate => diphosphate + gamma-terpinene


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Drosophila melanogaster)


name: METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Mus musculus)


name: dTDP-alpha-D-glucose => dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O


name: OPN (osteopontin) degradation by MMP3, MMP7 (Sus scrofa)


name: 2-oxoglutarate + [ribosomal protein S23]-L-proline + O2 = [ribosomal protein S23]-trans-3-hydroxy-L-proline + CO2 + succinate


name: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] => 16alpha,17alpha-dihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Canis familiaris)


name: Interaction of KIT and sSCF (Mus musculus)


name: D-glucose + sn-glycerol 3-phosphate = D-glucose 6-phosphate + glycerol


name: (indol-3-yl)acetate + H(+) + NADH + O2 = 2-hydroxy-(1H-indol-3-yl)acetate + H2O + NAD(+)


name: Degradation of ubiquitinated SMAD2 (Xenopus tropicalis)


name: H(+)(out) + sucrose(out) = H(+)(in) + sucrose(in)


name: ATP + pseudouridine => ADP + H(+) + psi-UMP


name: (2E,6E,10E)-geranylgeraniol + UTP => (2E,6E,10E)-geranylgeranyl phosphate + H(+) + UDP


name: 2-aminopentanenitrile + H(+) + 2 H2O <=> L-2-aminopentanoate + NH4(+)


name: an acyl-CoA + sn-glycerol 3-phosphocholine = a monoacyl-sn-glycero-3-phosphocholine + CoA


name: PPP1CC dephosphorylates PLK1 (Sus scrofa)


name: calcidiol + UDP-alpha-D-glucuronate <=> calcidiol 3-O-(beta-D-glucuronide) + H(+) + UDP


name: (E)-(indol-3-yl)acetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: p-S400-Cot phosphorylates NIK (Rattus norvegicus)


name: SMAC binds XIAP:Caspase-7 (Gallus gallus)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+) => 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADH


name: 2-methylpropanal O-methyloxime + H(+) + S-adenosyl-L-homocysteine => 2-methylpropanal oxime + S-adenosyl-L-methionine


name: ubiquitin-modified histone reader activity


name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Bos taurus)


name: 1,2,3-tripropanoylglycerol + H2O => dipropanoylglycerol + H(+) + propanoate


name: CDP-choline + H2O = CMP + 2 H(+) + phosphocholine


name: 2-glutathionyl-2-methylbut-3-en-1-ol <=> (3R)-3,4-epoxy-3-methylbut-1-ene + glutathione


name: Hydrolysis of PC to PA by PLD (Saccharomyces cerevisiae)


name: a fatty acid + L-tyrosine => an N-(fatty acyl)-L-tyrosine + H2O


name: O2 + phenylacetonitrile + reduced [NADPH--hemoprotein reductase] => (R)-mandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an aromatic oxo-acid + glycine => an aromatic L-alpha-amino acid + glyoxylate


name: p115-RhoGEF activation of RHOA (Bos taurus)


name: Association of MRE11 with RAD50 (Gallus gallus)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Gallus gallus)


name: Endonucleolytic RISC hydrolyzes target RNAs (Xenopus tropicalis)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Bos taurus)


name: Caspase 3-mediated cleavage of PKC delta (Homo sapiens)


name: CHEK1 phosphorylates RAD51 (Mus musculus)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Caenorhabditis elegans)


name: MICAL1 produces NADP+, H2O2 (Danio rerio)


name: chorismate + L-glutamine => 4-amino-4-deoxychorismate + L-glutamate


name: Elongation of pre-rRNA transcript (Gallus gallus)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Drosophila melanogaster)


name: H2O + trihexadecanoylglycerol <=> dihexadecanoylglycerol + H(+) + hexadecanoate


name: beta-ribofuranosylaminobenzene 5'-phosphate synthase activity


name: an aromatic primary alcohol + NAD(+) => an aromatic aldehyde + H(+) + NADH


name: Prolactin receptor ligands bind the prolactin receptor (Xenopus tropicalis)


name: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Xenopus tropicalis)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Canis familiaris)


name: Ubiquitination of NEMO by TRAF6 (Mus musculus)


name: a ubiquinone + caffeine + H2O <=> 1,3,7-trimethylurate + a ubiquinol


name: PIAS4 SUMOylates VHL with SUMO1 (Danio rerio)


name: ARF1:GTP binds Golgin TRIP11 (Mus musculus)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(in) + ATP + H2O <=> ADP + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(out) + H(+) + phosphate


name: all-trans-zeaxanthin + 2 UDP-alpha-D-glucose => 2 H(+) + 2 UDP + zeaxanthin bis(beta-D-glucoside)


name: a (2R)-2-hydroxycarboxylate + a halide anion + H(+) => an (S)-2-haloacid + H2O


name: "Enzymes altering nucleic acid conformation"


name: L1-FGFR cis-heterodimerization (Rattus norvegicus)


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Bos taurus)


name: PTK2beta binds alphaVbeta3 (Danio rerio)


name: Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 (Homo sapiens)


name: an inositol-1-phosphoceramide + H2O => 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Homo sapiens)


name: N-hydroxy-L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: an N-acylsphinganine + H2O => a fatty acid + sphinganine


name: The receptor:G-protein complex releases GDP (Rattus norvegicus)


name: [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide => [protein]-C-terminal glycine + NAD(+)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Rattus norvegicus)


name: a globoside Gb4Cer + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside IV3GalNAc-Gb4Cer + H(+) + UDP


name: (+)-dehydrodiconiferyl acid ketone + a quinone + H2O <=> (+)-dehydrodiconiferyl acid carboxylate + a quinol + H(+)


name: Active LTK phosphorylates IRS1 (Gallus gallus)


name: PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Sus scrofa)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Homo sapiens)


name: Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Sus scrofa)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Drosophila melanogaster)


name: SAMD8 transfers phosphatidyl from PE onto C16DH CER (Xenopus tropicalis)


name: Formation of ADAR1 homodimer (Rattus norvegicus)


name: PPP1CC dephosphorylates PLK1 (Canis familiaris)


name: Activated human JNKs migrate to nucleoplasm (Bos taurus)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Xenopus tropicalis)


name: FABP5:atRA translocates from cytosol to nucleoplasm (Bos taurus)


name: IkB is ubiquitinated and degraded (Homo sapiens)


name: alpha-D-glucose 1-phosphate + ATP <=> ADP + alpha-D-glucose 1,6-bisphosphate + H(+)


name: (2Z,6E)-farnesyl diphosphate => (Z)-alpha-bisabolene + diphosphate


name: A + D-proline = 1-pyrroline-2-carboxylate + AH2


name: diphosphate + syn-isopimara-7,15-diene => 9alpha-copalyl diphosphate


name: (S)-3-methyl-2-oxopentanoate + L-valine => 3-methyl-2-oxobutanoate + L-isoleucine


name: Fusion and Release of SARS-CoV-2 Nucleocapsid (Homo sapiens)


name: 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + L-serine => 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: (6-hydroxyhexanoyl)n-1 + 6-hydroxyhexanoate + H(+) => (6-hydroxyhexanoyl)n + H2O


name: 4-hydroxybenzoate + ATP + H(+) => 4-hydroxybenzoyl-5'-AMP + diphosphate


name: intercellular adhesion molecule-3 receptor binding


name: O2 + tetradecanoyl-CoA => (2E)-tetradecenoyl-CoA + H2O2


name: digitoxin + 2 Fe(II)-[cytochrome c] + 3 H(+) = dihydrodigitoxin + 2 Fe(III)-[cytochrome c]


name: CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Caenorhabditis elegans)


name: isovitexin + UDP-alpha-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Mus musculus)


name: EGFR non-clathrin mediated endocytosis (Sus scrofa)


name: AMP + diphosphate + L-isoleucyl-tRNA(Ile) => ATP + L-isoleucine + tRNA(Ile)


name: kermesate + UDP-alpha-D-glucose <=> carminate + 2 H(+) + UDP


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Mus musculus)


name: IL34 dimer:SDC1 binds CSF1R (Xenopus tropicalis)


name: acetate(out) + 2 Na(+)(out) <=> acetate(in) + 2 Na(+)(in)


name: RUNX3 binds SMAD3 and SMAD4 (Drosophila melanogaster)


name: Activated glucocorticoid receptor represses NPAS4 gene transcription (Homo sapiens)


name: Elastin degradation by MMP14 (Canis familiaris)


name: BRF1 Complex recruits RNA degradation activities (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 3-acyl-sn-glycerol => a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: [(1->2)-beta-D-glucosyl](n) + H2O <=> [(1->2)-beta-D-glucosyl](n-2) + sophorose


name: MADD exchanges GTP for GDP on RAB27 (Homo sapiens)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Danio rerio)


name: alpha-humulene + O2 + reduced [NADPH--hemoprotein reductase] = 10-hydroxy-alpha-humulene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphate


name: USP8 deubiquitinates LRIG1 (Gallus gallus)