name: adenosylcob(III)yrate + 4 ADP + 4 H(+) + 4 L-glutamate + 4 phosphate => adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O + 4 L-glutamine


name: GTSE1 binds microtubule lattice in interphase cells (Rattus norvegicus)


name: 2 3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + 2 O2 <=> formate + grixazone A + H(+) + 3 H2O


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Bos taurus)


name: 15alpha-stemmadenine + acetyl-CoA = CoA + O-acetyl-15alpha-stemmadenine


name: holo-[peptidyl-carrier protein] + L-glutamyl-5'-AMP <=> AMP + H(+) + L-glutamyl-[peptidyl-carrier protein]


name: a 2,3-dehydroacyl-CoA + AH2 => A + a 2,3-saturated acyl-CoA


name: Formation of the SET1A complex (Caenorhabditis elegans)


name: Translocation of Ezrin to plasma membrane (Drosophila melanogaster)


name: 25-hydroxyvitamin D2 + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 1alpha,25-dihydroxyvitamin D2 + H2O + 2 oxidized [adrenodoxin]


name: Release of platelet cytosolic components (Drosophila melanogaster)


name: (Z)-24-ethylidenelophenol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: 1D-myo-inositol 1,2,3-trisphosphate + H2O => 1D-myo-inositol 2,3-bisphosphate + phosphate


name: butan-2-one + H(+) + NADH + O2 = 1-hydroxy-2-butanone + H2O + NAD(+)


name: IFNG dimer binds IFNG inhibitors (Bos taurus)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-phenylalanyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-phenylalanine


name: (2S)-3-sulfolactaldehyde + dihydroxyacetone phosphate => 6-deoxy-6-sulfo-D-fructose 1-phosphate


name: D-glycero-D-manno-heptose 1,7-bisphosphate + H2O = D-glycero-D-manno-heptose 1-phosphate + phosphate


name: MAOB:FAD oxidatively deaminates of PEA (Danio rerio)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Dictyostelium discoideum)


name: (3R)-3-hydroxydecanoyl-CoA => (2E)-decenoyl-CoA + H2O


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Sus scrofa)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + 2 glutathione <=> (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: 1-propanol + NAD(+) = H(+) + NADH + propanal


name: MPP cleaves targeting peptide (presequence) of inner membrane precursors (Homo sapiens)


name: 27-hydroxycholesterol is 7alpha-hydroxylated (Sus scrofa)


name: (R)-lipoate + ATP + H(+) <=> (R)-lipoyl-5'-AMP + diphosphate


name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Xenopus tropicalis)


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Dictyostelium discoideum)


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Mus musculus)


name: 4alpha-carboxyzymosterol + NAD(+) => CO2 + NADH + zymosterone


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Mus musculus)


name: H(+) + hydrolyzed zearalenone => CO2 + decarboxylated hydrolyzed zearalenone


name: LIPs hydrolyse TG to DAG and RCOOH (Bos taurus)


name: (R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA => (R)-2-hydroxy-4-methylpentanoyl-CoA + 4-methylpentanoate


name: oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor


name: "With a quinone or similar compound as acceptor"


name: MKL1 translocates from cytosol to the nucleus (Drosophila melanogaster)


name: ATP + H2O + L-kynurenine(out) => ADP + H(+) + L-kynurenine(in) + phosphate


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Drosophila melanogaster)


name: Receptor CXCR6 binds CXCL16 ligand (Rattus norvegicus)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Bos taurus)


name: SALMs1-3 bind each other in cis interactions (Mus musculus)


name: Activated FGFR2:p-FRS bind to PPTN11 (Homo sapiens)


name: hexadecanoyl-CoA + octan-1-ol => CoA + octyl hexadecanoyl


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Rattus norvegicus)


name: a globoside GalGb4Cer + H2O <=> an N-acyl-sphingoid base + beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Rattus norvegicus)


name: carbendazim + H2O => 2-aminobenzimidazole + CO2 + methanol


name: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate


name: a (4S)-2,3-dehydroflavan-3,4-diol + H(+) <=> a 4-H-anthocyanidin with a 3-hydroxy group + H2O


name: Binding of NEP/NS2 to vRNP:M1 (Homo sapiens)


name: ESTG binds ESR2:chaperone complex (Gallus gallus)


name: Association of procollagen type III (Mus musculus)


name: RNF146 binds RibC-AXIN:TNKS complex (Canis familiaris)


name: Activation of cytosolic AMPK by phosphorylation (Mus musculus)


name: IL19 binds IL20RA:JAK1:IL20RB (Canis familiaris)


name: PDE5A dimer binds PDE5A inhibitors (Rattus norvegicus)


name: a ganglioside GD3 + acetyl-CoA = a ganglioside Ac-O-7-GD3 + CoA


name: 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA <=> 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP => (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate


name: LILRs interact with MHC Class I (Homo sapiens)


name: S-Farn-Me KRAS4B binds calmodulin (Canis familiaris)


name: Duplex siRNA is loaded into Argonaute (Rattus norvegicus)


name: HEXB cleaves the terminal GalNAc from DS (Drosophila melanogaster)


name: CoA + octyl hexadecanoyl => hexadecanoyl-CoA + octan-1-ol


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 <=> 5,10-methylenetetrahydromethanopterin + H(+)


name: Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)


name: (2E)-13-methyltetradecenoyl-CoA + H(+) + NADPH = isopentadecanoyl-CoA + NADP(+)


name: 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate => 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: 2-all-trans-decaprenylphenol + H(+) + NADPH + O2 = 3-(all-trans-decaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: 4-hydroxy-6-(2-oxotridecyl)pyran-2-one + 3 CO2 + 4 CoA => dodecanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: CHDH oxidises Cho to BETALD (Caenorhabditis elegans)


name: NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Bos taurus)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Danio rerio)


name: PGM1:Mg2+ isomerises G6P to G1P (Saccharomyces cerevisiae)


name: [(1->4)-alpha-D-galacturonosyl](n) + H2O => [(1->4)-alpha-D-galacturonosyl](n-2) + alpha-D-galacturonosyl-(1->4)-D-galacturonate


name: RHOD GAPs stimulate RHOD GTPase activity (Danio rerio)


name: (3,5-dihydroxyphenyl)acetyl-CoA + H2O => (3,5-dihydroxyphenyl)acetate + CoA + H(+)


name: NACT co-transports trivalent citrate and a sodium ion (Mus musculus)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Bos taurus)


name: Recruitment of POLB to the AP site (Dictyostelium discoideum)


name: CHGA-derived peptide binds the bacterial cell surface (Gallus gallus)


name: acetate + ATP + CoA <=> acetyl-CoA + AMP + diphosphate


name: (6E)-8-methylnon-6-enoyl-CoA + 4-hydroxy-3-methoxy-benzenemethanol <=> capsiate + CoA


name: 2,6,10,14-tetramethylpentadecanoate(in) + ATP + H2O => 2,6,10,14-tetramethylpentadecanoate(out) + ADP + H(+) + phosphate


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Mus musculus)


name: Hemoglobin A is protonated and carbamated causing release of oxygen (Gallus gallus)


name: Recruitment of PLC-gamma1 to SLP-76 (Mus musculus)


name: RAD51 gene expression is stimulated by E2F1 and inhibited by E2F6 (Homo sapiens)


name: CTP + H(+) + sn-glycerol 3-phosphate => CDP-glycerol + diphosphate


name: SLC46A1 transports hemes from extracellular region to cytosol (Rattus norvegicus)


name: dTDP-6-deoxy-alpha-D-allose + NAD(+) => dTDP-4-dehydro-6-deoxy-alpha-D-allose + H(+) + NADH


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Rattus norvegicus)


name: LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) (Bos taurus)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1 (d18:1(4E)) + CMP + H(+)


name: 3-oxo-(13Z,16Z,19Z)-docosatrienoyl-CoA + CO2 + CoA => (11Z,14Z,17Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA


name: RAS GAPs bind RAS:GTP (Rattus norvegicus)


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O => 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+)


name: Activated PCLG1 dissociates from NTRK2 (Mus musculus)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Mus musculus)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Drosophila melanogaster)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Danio rerio)


name: 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 (Homo sapiens)


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP


name: 19 H(+) + holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine => 9 CO2 + 9 CoA + dihydromonacolin L-[lovastatin nonaketide synthase] + 6 H2O + 11 NADP(+) + S-adenosyl-L-homocysteine


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Sus scrofa)


name: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H(+)


name: HSP70 binds to HSP40:nascent protein (Gallus gallus)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)


name: GADD45A binds AURKA (Drosophila melanogaster)


name: POLZ extends translesion synthesis (Saccharomyces cerevisiae)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Homo sapiens)


name: AFG3L2 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Rattus norvegicus)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Sus scrofa)


name: CCND1 binds RUNX3 and displaces EP300 (Canis familiaris)


name: EPCAM binds itself to form homotypic cell adhesion (Homo sapiens)


name: 3,4-dihydroxyphenylacetyl-CoA + H2O => 3,4-dihydroxyphenylacetate + CoA + H(+)


name: Phosphorylation of CBL (EGFR:CBL) (Bos taurus)


name: (3R)-hydroxyeicosanoyl-CoA + NAD(+) <=> 3-oxoeicosanoyl-CoA + H(+) + NADH


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Canis familiaris)


name: LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D (Rattus norvegicus)


name: Bradykinin receptors B1 and B2 bind to bradykinin (Rattus norvegicus)


name: eNoSC deacetylates histone H3 (Schizosaccharomyces pombe)


name: CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Gallus gallus)


name: 3-amino-2-hydroxy-4-methoxybenzoate + ATP + nitrite => AMP + cremeomycin + diphosphate + H2O


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ASAH1 hydrolyzes ceramide (Canis familiaris)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Xenopus tropicalis)


name: a 3-dehydro-D-glucoside => a 3-dehydro-D-guloside


name: UCHL3, SENP8 cleave NEDD8 (Dictyostelium discoideum)


name: TGFBR3 binding to ARRB1/2 (Rattus norvegicus)


name: sphing-4-enine 1-phosphate(out) => sphing-4-enine 1-phosphate(in)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Canis familiaris)


name: 2-oxo-3-sulfanylpropanoate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine


name: an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose => an alpha-D-mannosylinositol-1-phosphodihydroceramide + GDP + H(+)


name: H2O + N,N'-diacetylchitobiose <=> acetate + N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine


name: myo-inositol transmembrane transporter activity


name: FAHD1 dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)


name: SREBP1A,1C,2 binds Importin beta-1 (Canis familiaris)


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+) + H2O => Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + N-(2,3-dihydroxybenzoyl)-L-serine


name: AMP + diphosphate + heptanal + NADP(+) => ATP + H(+) + heptanoate + NADPH


name: Association of Securin with Cdc20:APC/C complex (Mus musculus)


name: DCN binds collagen I, II, III, VI fibrils (Mus musculus)


name: O2 + tetradecanedioyl-CoA => (2E)-tetradecenedioyl-CoA + H2O2


name: TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Canis familiaris)


name: an acyl-CoA + L-glutamine => an N(2)-acyl-L-glutamine + CoA + H(+)


name: aflatoxin B2 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase] => 8-O-methyldihydrosterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Canis familiaris)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Dictyostelium discoideum)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Dictyostelium discoideum)


name: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] => acetate + androst-4-ene-3,17-dione + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Bos taurus)


name: 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + H2O + NADP(+) => 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(+) + NADPH + O2


name: G alpha (q) in G (q):RGS complex is inactivated (Mus musculus)


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Mus musculus)


name: cytidine(2278) in 25S rRNA + S-adenosyl-L-methionine => 5-methylcytidine(2278) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Rattus norvegicus)


name: dimethyl sulfoxide + H(+) + NADH + O2 = dimethyl sulfone + H2O + NAD(+)


name: (E)-feruloyl-CoA + galactarate <=> 2-O-[(E)-feruloyl]-D-galactarate + CoA


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Bos taurus)


name: (S)-malate + ATP + CoA = (S)-malyl-CoA + ADP + phosphate


name: DHF is reduced to tetrahydrofolate (THF) (Rattus norvegicus)


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Rattus norvegicus)


name: GNRHR binds GNRHR peptide antagonists (Mus musculus)


name: FAICAR => IMP + H2O (Drosophila melanogaster)


name: EXT1:EXT2 transfer GlcNAc to the heparan chain (Drosophila melanogaster)


name: UXT gene expression is repressed by the PRC1L4 complex (Homo sapiens)


name: 4'-hydroxyechinenone + AH2 + O2 => 4',4'-dihydroxyechinenone + A + H2O


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Bos taurus)


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: "citrate synthase (unknown stereospecificity)"


name: (2E)-geranyl diphosphate <=> alpha-thujene + diphosphate


name: cGMP is degraded by PDEs (Dictyostelium discoideum)


name: SLC16A10-mediated uptake of aromatic amino acids (Danio rerio)


name: CYP11B2 18-hydroxylates CORST to 18HCORST (Mus musculus)


name: sn-glycerol 3-phosphate + ubiquinone-8 <=> dihydroxyacetone phosphate + ubiquinol-8


name: H2O + L-canavanine <=> L-homoserine + N-hydroxyguanidine


name: Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Homo sapiens)


name: acetyl-CoA + chrodrimanin A <=> chrodrimanin B + CoA


name: p-CD19:VAV binds PI3K and GRB2 (Canis familiaris)


name: NAGLU hydrolyses Heparan sulfate chain(4) (Rattus norvegicus)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)


name: H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH => N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+)


name: Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Sus scrofa)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CTP => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CDP + H(+)


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Sus scrofa)


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Rattus norvegicus)


name: SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)


name: (9Z)-octadecenoate + glycerol + H(+) => 2-(9Z-octadecenoyl)-glycerol + H2O


name: (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O => (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC (Bos taurus)


name: Interaction of DAP12 and KIR2DS5 (Homo sapiens)


name: Proteasome proteolyzes ub-HIF-alpha (Canis familiaris)


name: Active ARF recruits coatomer (Drosophila melanogaster)


name: chloride(in) + 2 Na(+)(in) + sarcosine(in) => chloride(out) + 2 Na(+)(out) + sarcosine(out)


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Bos taurus)


name: MAP2K2 phosphorylates MAPK1 (Rattus norvegicus)


name: Translocation of WWTR1 (TAZ) to the nucleus (Caenorhabditis elegans)


name: 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+) => 2,3-dihydroxy-p-cumate + O2


name: ATP + GDP = AMP + guanosine 3',5'-bis(diphosphate)


name: BLT receptors can bind LTB4 (Canis familiaris)


name: acetyl-CoA + gentamicin C = CoA + H(+) + N(3)-acetylgentamycin C


name: M6PR transports activated ARSA to the lysosome (Sus scrofa)


name: H2O + NAD(+) + succinate semialdehyde => 2 H(+) + NADH + succinate


name: Caspase-mediated cleavage of claspin (Rattus norvegicus)


name: SUMOylation of TOP2B with SUMO1 (Gallus gallus)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Caenorhabditis elegans)


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Rattus norvegicus)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Rattus norvegicus)


name: a ganglioside Ac-O-8-GD1a => a ganglioside Ac-O-7-GD1a


name: Spike trimer translocates to ERGIC (Homo sapiens)


name: (2R,3R)-dihydroquercetin + H(+) + NADPH + O2 => (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+)


name: HMGB1 binds TLR4:LY96 (Rattus norvegicus)


name: Addition of the third nucleotide on the nascent transcript (Schizosaccharomyces pombe)


name: 2 chloride(out) + K(+)(out) + Na(+)(out) = 2 chloride(in) + K(+)(in) + Na(+)(in)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Homo sapiens)


name: Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Sus scrofa)


name: Collagen types VI, IX bind integrin alpha10beta1 (Mus musculus)


name: TFAP2C translocates to the nucleus (Xenopus tropicalis)


name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor


name: ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC (Canis familiaris)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Danio rerio)


name: Addition of galactose to Core 6 glycoprotein (Bos taurus)


name: Urotensin-2 receptor binds urotensin-2 and 2B (Sus scrofa)


name: Release of Cytochrome c from mitochondria (Saccharomyces cerevisiae)


name: α1-antagonists bind ADRA1A,B,D (Canis familiaris)


name: SUMOylation of NOP58 with SUMO2 (Xenopus tropicalis)


name: (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate => (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O


name: Removal of the third glucose by glucosidase II and release from the chaperone (Homo sapiens)


name: L-histidine(in) + L-tryptophan(out) => L-histidine(out) + L-tryptophan(in)


name: XYLB phosphorylates D-xylulose (Danio rerio)


name: 16beta,17beta-estriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase]


name: H2O + N(1)-(3-aminopropyl)agmatine = spermidine + urea


name: (-)-alpha-isocomene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (6Z,9Z,12Z)-octadecatrienoate + O2 <=> 10-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate


name: SENP1,2,5 proteolytically process SUMO3 (Plasmodium falciparum)


name: 3'-phosphoadenylyl sulfate + taurodeoxycholate => 3alpha-sulfotaurodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: 2-phenylethylamine + H2O + O2 = 2-phenylacetaldehyde + H2O2 + NH4(+)


name: Estrogen stimulates dimerization of plasma membrane estrogen receptors (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Rattus norvegicus)


name: Histone acetyltransferases are recruited to the TFF1 gene (Homo sapiens)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Gallus gallus)


name: RHOG binds effectors at the plasma membrane (Rattus norvegicus)


name: 2 H2O + 2 L-dehydroascorbate => 2 L-ascorbate + O2


name: Histone acetyltransferases are recruited to the TFF1 gene (Saccharomyces cerevisiae)


name: (5R)-hydroxy-beta-trans-bergamotene + O2 = (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + H2O


name: Activation of NLK (Drosophila melanogaster)


name: 2 H2O + 3 NADP(+) + NH4(+) => 5 H(+) + 3 NADPH + nitrite


name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Gallus gallus)


name: dAMP(in) + NAD(+)(out) => dAMP(out) + NAD(+)(in)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-mannosylinositol-1-phosphoceramide = a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-alpha-mannosylinositol-1-phosphoceramide


name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Sus scrofa)


name: H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH => N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate


name: Association of DFF40 with DFF45 (Mus musculus)


name: apo-UQCRFS1 binds LYRM7 (Drosophila melanogaster)


name: H2O + N(6)-(2E)-butenoyl-L-lysyl-[protein] = (2E)-2-butenoate + L-lysyl-[protein]


name: 2xPDXK:2xZn2+ phosphorylates PXL (Xenopus tropicalis)


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Bos taurus)


name: Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor (Rattus norvegicus)


name: Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Sus scrofa)


name: N-hydroxy-L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: P2X1-mediated entry of Ca++ from plasma (Mus musculus)


name: Secretion of transmembrane collagens (Canis familiaris)


name: GSDMD oligomerizes into arc-, slit-shaped structures (Canis familiaris)


name: (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Rattus norvegicus)


name: anthranilate + S-adenosyl-L-methionine = H(+) + N-methylanthranilate + S-adenosyl-L-homocysteine


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Sus scrofa)


name: PIAS2-1 SUMOylates PARK7 with SUMO1 (Homo sapiens)


name: NEU1 hydrolyses Neu5Ac from glycoconjugates (Xenopus tropicalis)


name: small conductance calcium-activated potassium channel inhibitor activity


name: 2 L-cysteine => L-alanine + S-sulfanyl-L-cysteine


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Danio rerio)


name: p-Y693-STAT4 dissociates after IL12:IL12R interaction (Canis familiaris)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: (9Z)-tetradecenoyl-CoA + AMP + diphosphate => (9Z)-tetradecenoate + ATP + CoA


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O <=> 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+)


name: CTP(in) + dUMP(out) => CTP(out) + dUMP(in)


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Mus musculus)


name: uridine(54) in tRNA => pseudouridine(54) in tRNA


name: a 5'-end ribonucleotide-RNA + a ribonucleoside 5'-triphosphate + ATP + H2O <=> a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + AMP + 2 diphosphate + H(+)


name: CYP1A2 hydroxylates AFB1 to AFM1 (Homo sapiens)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Sus scrofa)


name: Mitochondrial intermembrane PRIN9 translocates to mitochondrial matrix (Homo sapiens)


name: Interaction of Afadin with F-actin (Homo sapiens)


name: SEMA5A binds to PLXNB3 (Canis familiaris)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Caenorhabditis elegans)


name: (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O <=> bisdemethoxycurcumin + CO2 + 2 CoA


name: C-C motif chemokine 21 receptor activity


name: TNF-alpha inhibitors bind to TNF(1-233) trimer (Danio rerio)


name: 2 CO2 + H(+) + NADH + 2 reduced [2Fe-2S]-[ferredoxin] => 2 formate + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin]


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O


name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + phytol = (7Z,10Z,13Z)-hexadecatrienoate phytyl ester + CoA


name: active monoatomic ion transmembrane transporter activity


name: H2O + N-hexadecanoylethanolamine => ethanolamine + hexadecanoate


name: p-STAT1dimer:KPNA1 binds KPNB1 (Sus scrofa)


name: 2-acyl LPC is acylated to PC by LPCAT (Danio rerio)


name: H2O + 2 monodehydro-L-ascorbate radical + N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine => 2 L-ascorbate + N-(9Z,12Z,15Z)-octadecatrienoylglycine + O2


name: (2R,3S)-tartrate + NAD(+) <=> dihydroxyfumarate + H(+) + NADH


name: SULTs transfer (SO4)2- group to 27HCHOL (Homo sapiens)


name: a D-glucoside + 2 Fe(III)-[cytochrome c] => a 3-dehydro-D-glucoside + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Dictyostelium discoideum)


name: a ganglioside GM4 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP + H(+)


name: UGT1A3 lactonizes ATV to ATVL (Rattus norvegicus)


name: 17alpha-hydroxyprogesterone + NADPH + O2 = acetate + androst-4-ene-3,17-dione + H2O + NADP(+)


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Sus scrofa)


name: 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose => 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: PIAS4 SUMOylates TP53BP1 with SUMO1 (Bos taurus)


name: MEOS oxidizes ethanol to acetaldehyde (Sus scrofa)


name: ANOs transport cytosolic Cl- to extracellular region (Bos taurus)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  (Gallus gallus)


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]


name: a methylated primary amine + H(+) + S-adenosyl-L-homocysteine => a primary amine + S-adenosyl-L-methionine


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Mus musculus)


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acyl-(4R)-4-hydroxysphinganine => a 1,2-diacyl-sn-glycerol + an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP


name: SMAC (DIABLO) forms dimer (Gallus gallus)


name: 6-hydroxytryprostatin B + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + tryprostatin A


name: 1,2-dehydroreticuline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase]


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)


name: acyl-phosphate glycerol-3-phosphate acyltransferase activity


name: general transcription initiation factor activity


name: adenosine(1914)/adenosine(1915) in 18S rRNA + 4 S-adenosyl-L-methionine <=> 4 H(+) + N(6)-dimethyladenosine(1914)/N(6)-dimethyladenosine(1915) in 18S rRNA + 4 S-adenosyl-L-homocysteine


name: "lipopolysaccharide core heptose(I) kinase"


name: H2O + Met-enkephalin-Arg-Phe <=> L-arginyl-L-phenylalanine + Met-enkephalin


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + pentalenene


name: (3R)-hydroxy-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + NADP(+) => (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA + H(+) + NADPH


name: (2Z,6Z)-farnesyl diphosphate => (E)-gamma-bisabolene + diphosphate


name: A + a 3-demethylubiquinol + H2O => a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2


name: nicotinate + S-adenosyl-L-methionine = N-methylnicotinate + S-adenosyl-L-homocysteine


name: KRAB-ZFP binds retroelement DNA in chromatin (Drosophila melanogaster)


name: DLST transfers succinyl to CoA (Canis familiaris)


name: Cho transports from the extracellular space to the cytosol (Dictyostelium discoideum)


name: (1R,5S)-carveol + NAD(+) <=> (S)-carvone + H(+) + NADH


name: Neuromedin-U receptors bind neuromedins U, S (Sus scrofa)


name: beta-D-glucosyl-(1->4)-D-galactose + phosphate <=> alpha-D-glucose 1-phosphate + D-galactose


name: ATP + thiamine phosphate => ADP + thiamine diphosphate


name: acetyl-CoA + kanamycin B = CoA + H(+) + N(6')-acetylkanamycin B


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + dimethylallyl diphosphate => (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + diphosphate


name: LIPT2 transfers octanoyl group to GCSH (Caenorhabditis elegans)


name: CO2 + diphosphate + nicotinate beta-D-ribonucleotide => 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate


name: (d)AMP + ATP <=> (d)ADP + ADP (AK1) (Caenorhabditis elegans)


name: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+)


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Homo sapiens)


name: 2-oxoglutarate + N(2)-succinyl-L-ornithine => L-glutamate + N-succinyl-L-glutamate 5-semialdehyde


name: 2 4-sulfanylbutanoate + NAD(+) => 4,4'-disulfanyldibutanoate + H(+) + NADH


name: AMP + butanoyl-CoA + diphosphate => ATP + butanoate + CoA


name: PKC phosphorylates sphingosine kinase 1 (Sus scrofa)


name: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH4(+) + pyruvate


name: beta-nicotinamide D-riboside + phosphate => beta-nicotinamide D-ribonucleotide + H2O


name: ADP + ATP <=> adenosine 3'-diphosphate,5'-diphosphate + AMP


name: a 1,3-diacyl-sn-glycerol + H2O => a fatty acid + a monoacylglycerol + H(+)


name: ATP binding to HSP90 triggers conformation change (Xenopus tropicalis)


name: SLC50A1 transports Glc from cytosol to extracellular region (Mus musculus)


name: H(+) + nonanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-nonenoyl-CoA + reduced [electron-transfer flavoprotein]


name: SLC22A12 exchanges extracellular urate for cytosolic LACT (Sus scrofa)


name: glycine(in) + Na(+)(in) <=> glycine(out) + Na(+)(out)


name: L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: Reuptake of serotonin from the synapse (Homo sapiens)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Danio rerio)


name: Autocatalytic phosphorylation of FGFR3c (Gallus gallus)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Sus scrofa)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Bos taurus)


name: CBL ubiquitinates FRS2 and FGFR3 (Canis familiaris)


name: Cross-linking of FCGRIIA with IgG-coated Ag (Sus scrofa)


name: carbaryl + H(+) + H2O <=> 1-naphthol + CO2 + methylamine


name: H2O + N-terminal L-arginyl-L-amino acid-[protein] = an N-terminal L-alpha-aminoacyl-[protein] + L-arginine


name: 2 S-adenosyl-L-methionine + sarcosine => glycine betaine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: Gs activation by prostacyclin receptor (Xenopus tropicalis)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen (Rattus norvegicus)


name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Sus scrofa)


name: 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine <=> 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: myricetin + S-adenosyl-L-methionine = 7-O-methylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: Pellino ubiquitinates IRAK1 (Schizosaccharomyces pombe)


name: EVL:PPL heterodimer binds the inner surface of the plasma membrane (Homo sapiens)


name: FN3K phosphorylates ketosamines (Homo sapiens)


name: dimethylallyl diphosphate + preechinulin <=> diphosphate + tardioxopiperazine A


name: GRB2:GAB1 binds to phosphorylated EGFR (Sus scrofa)


name: Interleukin-27 binds Interleukin-27 receptor (Homo sapiens)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+) => a ribonucleotidyl-ribonucleotide-RNA + H2O


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol => 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: AMP + diphosphate + octadecanoyl-CoA => ATP + CoA + octadecanoate


name: FAD + H(+) + nonanoyl-CoA <=> (2E)-nonenoyl-CoA + FADH2


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Sus scrofa)


name: 2'-deoxymugineate + 2-oxoglutarate + O2 <=> 3-epihydroxy-2'-deoxymugineate + CO2 + H(+) + succinate


name: pseudouridine(38/39) in tRNA => uridine(38/39) in tRNA


name: arginine + H2O => ornithine + urea [ARG2] (Caenorhabditis elegans)


name: Activation of conventional Protein Kinase C (Mus musculus)


name: 2-oxobutanoate + L-methionine <=> (2S)-2-aminobutanoate + 4-methylsulfanyl-2-oxobutanoate


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)


name: CS acetylates OA to citrate (Saccharomyces cerevisiae)


name: Recruitment of Rad17-RFC complex to DNA (Homo sapiens)


name: Activated FGFR4 phosphorylates FRS3 (Sus scrofa)


name: AMP + diphosphate + octanedioyl-CoA => ATP + CoA + octanedioate


name: IGFBP1 binds IGF forming IGF:IGFBP1 (Gallus gallus)


name: PGM1:Mg2+ isomerises G6P to G1P (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (2E,6E,10E)-geranylgeraniol + diphosphate


name: RNF41 binds neuregulin-activated ERBB3 (Gallus gallus)


name: butanoyl-CoA + ethanol => CoA + ethyl butanoate


name: Active LTK binds GRB2:TNK2 (Mus musculus)


name: PLB1 hydrolyses RPALM to atROL (Canis familiaris)


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Bos taurus)


name: Phosphorylation and activation of eIF4B by activated S6K1 (Homo sapiens)


name: PRKAA2 regulated nuclear export of NFE2L2 (Rattus norvegicus)


name: RIP2 induces K63-linked ubiquitination of NEMO (Mus musculus)


name: 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Rattus norvegicus)


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Rattus norvegicus)


name: H(+) + NADH + phenylglyoxylate => (R)-mandelate + NAD(+)


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Bos taurus)


name: GRK1,4,7 phosphorylate MII to p-MII (Danio rerio)


name: STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Bos taurus)


name: 2-oxobutanoate + L-histidine => (2S)-2-aminobutanoate + 3-(imidazol-5-yl)pyruvate


name: holo-[CmaD peptidyl-carrier protein] + L-alloisoleucyl-[CmaA peptidyl-carrier protein] = holo-[CmaA peptidyl-carrier protein] + L-alloisoleucyl-[CmaD peptidyl-carrier protein]


name: L-cysteine(in) + L-methionine(out) => L-cysteine(out) + L-methionine(in)


name: Engulfment of particulate antigen into phagocytic vesicle (Gallus gallus)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Gallus gallus)


name: acetaldehyde + H(+) + sulfite => 2-hydroxyethane-1-sulfonate


name: Endocytosis of cya:lef:(pagA(197-794):ANTXR2 oligomer) (plasma membrane to endosome membrane) (Homo sapiens)


name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter (Homo sapiens)


name: [cis-1,4-isoprene](n) + O2 = (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal + cis-1,4-isoprene(n-3)


name: Budding of COPII coated vesicle (Sus scrofa)


name: RAC1 and CDC42 activate PAK2 (Rattus norvegicus)


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Mus musculus)


name: p-T,Y MAPKs dimerize (Drosophila melanogaster)


name: DELE1(143-515) is released into the cytosol (Bos taurus)


name: PI3K associates with phosphorylated GAB2 (Xenopus tropicalis)


name: 2-oxoglutarate + deacetoxyvindoline + O2 = 4-O-deacetylvindoline + CO2 + succinate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active ALK phosphorylates PLCG1 (Mus musculus)


name: (R)-8-oxocitronellyl enol + NADP(+) = (6E)-8-oxogeranial + H(+) + NADPH


name: ATP + H2O + prostaglandin E2(in) = ADP + H(+) + phosphate + prostaglandin E2(out)


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Mus musculus)


name: H2O + L-tryptophan + O2 <=> H2O2 + indole-3-pyruvate + NH4(+)


name: Exogenous soluble antigen targeted to more stable early endosome (Xenopus tropicalis)


name: (3S)-3-hydroxy-D-aspartate => glycine + glyoxylate


name: dopamine + secologanin => H2O + N-deacetylipecoside


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Homo sapiens)


name: SGTA binds Tail-anchored protein (Drosophila melanogaster)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Sus scrofa)


name: ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] => ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate


name: pro-SFTPB translocates from ER membrane to multivesicle body (Caenorhabditis elegans)


name: ATP + H(+) + NADPH + nonanoate = AMP + diphosphate + NADP(+) + nonanal


name: ATP + glycoursodeoxycholate(in) + H2O = ADP + glycoursodeoxycholate(out) + H(+) + phosphate


name: acetyl-CoA + L-2,4-diaminobutanoate = (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Caenorhabditis elegans)


name: RPE dimers isomerise RU5P to XY5P (Mus musculus)


name: Importin-8 binds AGO2:miRNA (Homo sapiens)


name: FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Homo sapiens)


name: H(+) + N,N-dihydroxy-L-tetrahomomethionine = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Canis familiaris)


name: Ub,pS335,S338,T NFE2L2 is degraded (Danio rerio)


name: YWHAB dimer dissociates from dephosphorylated RAF (Mus musculus)


name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions (Homo sapiens)


name: AUF1:mRNA complex is destroyed (Plasmodium falciparum)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: RHOV binds effectors at the plasma membrane (Schizosaccharomyces pombe)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> diphosphate + preasperterpenoid A


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Bos taurus)


name: 5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10-methylenetetrahydromethanopterin + H2O


name: H(+)(in) + xanthine(in) <=> H(+)(out) + xanthine(out)


name: 1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H(+)


name: neutral L-amino acid transmembrane transporter activity


name: USP18 binds IKBKG within IKK complex (Canis familiaris)


name: ATP + L-seryl-[protein] => ADP + H(+) + O-phospho-L-seryl-[protein]


name: Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Homo sapiens)


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Saccharomyces cerevisiae)


name: 3'-phosphoadenylyl sulfate + 3,3',5-triiodo-L-thyronine => 3,3',5-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: H2O + hypochlorous acid => chloride + H(+) + H2O2


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Mus musculus)


name: TBK1 binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3  (Homo sapiens)


name: a 5'-end guanosine-5'-diphospho-5'-(2'-deoxyribonucleoside)-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + GMP + 2 H(+)


name: H2O2 + oxidized [rubredoxin] => 2 H(+) + reduced [rubredoxin] + superoxide


name: D-glucaro-1,5-lactone + H(+) + NADH => beta-D-glucuronate + NAD(+)


name: AMOT proteins bind WWTR1 (TAZ) (Sus scrofa)


name: Orc1 is phosphorylated by cyclin A/CDK2 (Homo sapiens)


name: a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)


name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Rattus norvegicus)


name: tBID activates BAX protein (Mus musculus)


name: Nascent G signal peptide is cleaved at ER membrane (Homo sapiens)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Dictyostelium discoideum)


name: Degradation of ubiquitinated SMAD2 (Homo sapiens)


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Drosophila melanogaster)


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Drosophila melanogaster)


name: 6-deoxy-6-sulfo-D-fructose + ATP = 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H(+)


name: NT5C3B hydrolyses 7MGP to 7MG (Gallus gallus)


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Rattus norvegicus)


name: a very-long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) <=> 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH


name: H2O + L-fucono-1,4-lactone = H(+) + L-fuconate


name: CDT1-mediated loading of MCM2-7 to replication origins (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CDP + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CTP


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Rattus norvegicus)


name: carbovir diphosphate + ATP => carbovir triphosphate + ADP (Homo sapiens)


name: H2O + L-glutamine + O2 = 2-oxoglutaramate + H2O2 + NH4(+)


name: (2E)-dodecenoyl-CoA + H2O <=> (2E)-dodecenoate + CoA + H(+)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Bos taurus)


name: 2,3,6-trichlorohydroquinone + chloride + glutathione disulfide => 2,3,5,6-tetrachlorohydroquinone + 2 glutathione


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Gallus gallus)


name: PANK2 phosphorylates PanK (Drosophila melanogaster)


name: IL10 positively regulates extracellular inflammatory mediators (Homo sapiens)


name: 8-O-methyldihydrosterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = aflatoxin B2 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase]


name: 6 H(+) + hexanoyl-[ACP] + 7 malonyl-CoA <=> 7 CO2 + 7 CoA + 2 H2O + holo-[ACP] + noranthrone


name: (2E)-geranyl diphosphate <=> diphosphate + tricyclene


name: SUMOylation of TFAP2C with SUMO1 (Xenopus tropicalis)


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + O2 + reduced [NADPH--hemoprotein reductase] => 5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (R)-S-adenosyl-L-methionine + H2O => adenosine + H(+) + L-methionine


name: p-S115 MAPKAPK5 translocates to the cytosol (Rattus norvegicus)


name: all-trans-retinol + hexadecanoyl-CoA <=> all-trans-retinyl hexadecanoate + CoA


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Caenorhabditis elegans)


name: SUMOylation of TOPORS with SUMO1 (Xenopus tropicalis)


name: dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP(+) = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H(+) + NADPH


name: cAMP induces dissociation of inactive PKA tetramers (Caenorhabditis elegans)


name: UDP-alpha-D-glucose + vancomycin aglycone = devancoaminyl-vancomycin + UDP


name: pre-VLDL translocates from RER membrane to SER lumen (Sus scrofa)


name: SERPINA5 binds activated protein C (Canis familiaris)


name: Expression of PDPN in primordial germ cells (Homo sapiens)


name: Ferriheme is transferred from Albumin to Hemopexin (Xenopus tropicalis)


name: Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA (Mus musculus)


name: (3S)-hydroxytetradecanedioyl-CoA => (2E)-tetradecenedioyl-CoA + H2O


name: CoA + H(+) + phosphinomethylmalate => 3-(hydrohydroxyphosphoryl)pyruvate + acetyl-CoA + H2O


name: RHOA:GTP translocates to the ER membrane (Homo sapiens)


name: ferruginol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + pisiferate


name: AH2 + echinenone + O2 <=> 4'-hydroxyechinenone + A + H2O


name: 3-methyl-2-oxobutanoate(out) + H(+)(out) <=> 3-methyl-2-oxobutanoate(in) + H(+)(in)


name: Gq activation by TP receptor (Caenorhabditis elegans)


name: [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA <=> [(2->6)-alpha-D-glucosyl-(1->4)-N,7-O-diacetyl-alpha-D-neuraminosyl](n) + n CoA


name: a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP <=> a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP


name: an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine => an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Sus scrofa)


name: Translocation of STAT1 dimer to nucleus (Sus scrofa)


name: Formation of N-glucuronides (Sus scrofa)


name: an aldehyde + H(+) + H2O2 + nitrite => a primary nitroalkane + H2O + O2


name: (E)-feruloyl-AMP + CoA = (E)-feruloyl-CoA + AMP + H(+)


name: Phosphorylation and activation of Ezrin (Homo sapiens)


name: Formation of the PINCH-ILK-parvin complex (Homo sapiens)


name: H2O + L-alanine + O2 <=> H2O2 + NH4(+) + pyruvate


name: (2E,6E)-farnesyl diphosphate <=> (-)-delta-cadinene + diphosphate


name: AMP + diphosphate + H(+) + holo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] => apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + ATP + biotin


name: N-geranyl-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N-(8'-hydroxygeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase]


name: a medium-chain fatty acyl-CoA + H2O <=> a medium chain fatty acid + CoA + H(+)


name: Sequestration of BAD protein by 14-3-3 (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + menadiol => diphosphate + menaquinol-4


name: Vesicular inhibitory amino acid transport (Homo sapiens)


name: 12-hydroxyoctadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(13-hydroxy-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: 2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine = 3-amino-2,3-dideoxy-scyllo-inosose + 5'-deoxyadenosine + H(+) + L-methionine


name: an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H2O = a thymidine in DNA + ADP-D-ribose


name: ADP + H(+) + lipid A-core(out) + phosphate => ATP + H2O + lipid A-core(in)


name: Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Gallus gallus)


name: Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Mus musculus)


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Canis familiaris)


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Rattus norvegicus)


name: (4Z,15Z)-bilirubin IXalpha + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Bos taurus)


name: GBA3 hydrolyzes GlcCer (cytosol) (Canis familiaris)


name: (R)-3-phosphomevalonate + ATP = (R)-3,5-bisphosphomevalonate + ADP + H(+)


name: RFK:Mg2+ phosphorylates RIB (Mus musculus)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate = alpha-himachalene + diphosphate


name: Activation of proMMP11 by FURIN (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with Tenascin (Homo sapiens)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Drosophila melanogaster)


name: Collagen type XXV ectomain shedding (Xenopus tropicalis)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Sus scrofa)


name: (9Z)-octadecenoate + L-methionine => H2O + N-(9Z-octadecenoyl)-L-methionine


name: Start codon recognition (Dictyostelium discoideum)


name: 2-oxoglutarate + beta-alanine <=> 3-oxopropanoate + L-glutamate


name: TP73 tetramer translocates to the nucleus (Gallus gallus)


name: ATP + guanine(out) + H2O = ADP + guanine(in) + H(+) + phosphate


name: (2E,6E)-farnesyl diphosphate + H2O => (3S,6E)-nerolidol + diphosphate


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Danio rerio)


name: RNASEL cleaves cellular ssRNA (Gallus gallus)


name: Formation of RAD50:MRE11 complex (Rattus norvegicus)


name: baicalin + UDP => baicalein + UDP-alpha-D-glucuronate


name: ATP + decanoate + H(+) => decanoyl-AMP + diphosphate


name: O2 + reduced [NADPH--hemoprotein reductase] + tetracosanoate = 24-hydroxytetracosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: keto-L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH


name: Translocation of activated BAD protein to mitochondria (Sus scrofa)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate <=> phenylacetonitrile + sulfate + sulfur


name: ARSB hydrolyses C4S/C6S chains (Bos taurus)


name: GPR35 binds kynurenic acid (Gallus gallus)


name: gypsogenin + O2 + reduced [NADPH--hemoprotein reductase] <=> gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2,3-trihydroxybenzene + CO2 => 3,4,5-trihydroxybenzoate + H(+)


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Saccharomyces cerevisiae)


name: Release of GABA at the synapse (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: acetyl-CoA + oxalate = acetate + oxalyl-CoA


name: (9Z,12Z)-octadecadienoate + 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O


name: Src activation following P2Y purinoceptor activation (Canis familiaris)


name: FANCD2 deubiquitination by USP1:WDR48 (Canis familiaris)


name: CUL9:RBX1 ubiquitinates BIRC5 (Xenopus tropicalis)


name: JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Mus musculus)


name: AH2 + kynurenate + O2 <=> 7,8-dihydro-7,8-dihydroxykynurenate + A


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Homo sapiens)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Danio rerio)


name: H(+) + menaquinol-13 + S-adenosyl-L-homocysteine => 2-demethylmenaquinol-13 + S-adenosyl-L-methionine


name: SLC22A1 transports Cipro into hepatic cell (Homo sapiens)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Homo sapiens)


name: 3',5'-cyclic GMP + NAD(+) = H(+) + N(2)-(ADP-D-ribosyl)-3',5'-cyclic GMP + nicotinamide


name: H2O + neocasomorphin = L-isoleucine + neocasomorphin-(1-5)


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Bos taurus)


name: dehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) => dehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: 2 (S)-lactate(in) + prostaglandin D2(out) = 2 (S)-lactate(out) + prostaglandin D2(in)


name: CARNMT1 methylates CARN to Anserine (Drosophila melanogaster)


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Dictyostelium discoideum)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Bos taurus)


name: Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Sus scrofa)


name: PLC-gamma binds to the active receptor (Xenopus tropicalis)


name: ATP + RNA(n) => diphosphate + RNA(n)-3'-adenine ribonucleotide


name: (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 oxidized [adrenodoxin]


name: ADP + H(+) + sucrose => ADP-alpha-D-glucose + D-fructose


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Sus scrofa)


name: n H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) => n H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out)


name: 5-hydroxyuridine(34) in tRNA + S-adenosyl-L-methionine <=> 5-methoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + pyruvate <=> L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphoenolpyruvate


name: Activated human JNKs migrate to nucleoplasm (Rattus norvegicus)


name: Release of GABA at the synapse (Caenorhabditis elegans)


name: 2,4-diacetylphloroglucinol + H2O = 2-acetylphloroglucinol + acetate


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Xenopus tropicalis)


name: all-trans-zeaxanthin + O2 = (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O


name: L-arginine(out) + L-cysteine(in) + Na(+)(in) => L-arginine(in) + L-cysteine(out) + Na(+)(out)


name: Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: octacosanoyl-CoA + sphinganine <=> CoA + H(+) + N-(octacosanoyl)-sphinganine


name: IDH3 complex decarboxylates isocitrate (Schizosaccharomyces pombe)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Drosophila melanogaster)


name: Thrombin-activated PARs:Gq (active) dissociate (Gallus gallus)


name: a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GT1balpha + CMP + H(+)


name: a (3S)-3-hydroxyacyl-CoA + NAD(+) => a 3-oxoacyl-CoA + H(+) + NADH


name: H2O + N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: Depolymerization of lamin filaments after PKC-mediated phosphorylation (Mus musculus)


name: NADH + 2 O2 => H(+) + NAD(+) + 2 superoxide


name: 19-oxo-11-deoxycorticosterone + 2 H2O + 2 oxidized [adrenodoxin] => 19-hydroxy-11-deoxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: AKR1A1 reduces D-glucuronate to L-gulonate (Schizosaccharomyces pombe)


name: p-STAT3 dimerizes (Dictyostelium discoideum)


name: (2E,6E,10E)-geranylgeranyl phosphate + GDP + H(+) => (2E,6E,10E)-geranylgeraniol + GTP


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Caenorhabditis elegans)


name: all-trans-decaprenyl diphosphate + 7 diphosphate => (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate


name: RPA binds to the Flap (Rattus norvegicus)


name: 11-oxo-beta-amyrin + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => beta-amyrin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: GLI2,3 are degraded by the proteasome (Danio rerio)


name: BTK in G alpha (12)-BTK complex is activated (Gallus gallus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA


name: FASTKD2 binds 16S rRNA and MT-ND6 mRNA (Homo sapiens)


name: RHOQ binds effectors at the plasma membrane (Homo sapiens)


name: SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Canis familiaris)


name: (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H(+) + H2O => (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Plasmodium falciparum)


name: TRPs transport extracellular Ca2+ to cytosol (Xenopus tropicalis)


name: Caspase-mediated cleavage of Lamin B1 (Rattus norvegicus)


name: [pyruvate, water dikinase]-phosphate + H(+) + phosphate <=> [pyruvate, water dikinase] + diphosphate


name: soyasapogenol B + UDP-alpha-D-glucuronate = H(+) + soyasapogenol B 3-O-beta-D-glucuronate + UDP


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Danio rerio)


name: Exocytosis of ficolin-rich granule membrane proteins (Saccharomyces cerevisiae)


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Caenorhabditis elegans)


name: 2-dehydro-L-erythronate + H(+) + NADH => L-threonate + NAD(+)


name: 3-oxooctadecanoyl-CoA + H(+) + NADH => (3R)-hydroxyoctadecanoyl-CoA + NAD(+)


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-tetradecanoyl-sn-glycero-3-phosphocholine


name: H2O + hexano-6-lactone = 6-hydroxyhexanoate + H(+)


name: ATM phosphorylates TTC5 (Canis familiaris)


name: (E)-hept-2-enal + H2O + NAD(+) = (E)-hept-2-enoate + 2 H(+) + NADH


name: 2-oxoglutarate + O2 + octyl sulfate = CO2 + H(+) + octanal + succinate + sulfate


name: (2S)-2-amino-4-deoxychorismate = anthranilate + H(+) + pyruvate


name: Salvage - Sepiapterin is reduced to BH2 (Drosophila melanogaster)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Mus musculus)


name: reduced coenzyme F420:heterodisulfide oxidoreductase activity


name: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP => 8-desmethylnovobiocic acid + AMP + diphosphate


name: D-sorbitol + NADP(+) <=> H(+) + keto-L-sorbose + NADPH


name: NADP(+) + UDP-N-acetyl-alpha-D-muramate => H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine


name: 3'-phosphoadenylyl sulfate + 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) => 3alpha-hydroxyetiocholan-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA <=> 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: Cleavage of Procaspase‑9 to caspase‑9 (Bos taurus)


name: acetoin + NADP(+) => diacetyl + H(+) + NADPH


name: 4-(dimethylamino)azobenzene + 2 H(+) + 2 NADPH => aniline + N,N-dimethyl-1,4-phenylenediamine + 2 NADP(+)


name: Formation of the MLL3 complex (Homo sapiens)


name: Cargo-carrying vesicles bud from the TGN (Canis familiaris)


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Xenopus tropicalis)


name: a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)


name: Recruitment of elongation factors to form elongation complex (Mus musculus)


name: Binding of TFIIE to the growing preinitiation complex (Mus musculus)


name: PE is methylated to PC by PEMT (Dictyostelium discoideum)


name: GBA3 hydrolyzes GlcCer (cytosol) (Homo sapiens)


name: 2-oxoglutarate + L-arginine = 5-guanidino-2-oxopentanoate + L-glutamate


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(in) => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(out)


name: acetoacetate(out) + Na(+)(out) = acetoacetate(in) + Na(+)(in)


name: 2-oxoglutarate + L-proline + O2 = cis-3-hydroxy-L-proline + CO2 + succinate


name: 2 5'-dehydroinosine + O2 => 2 9-riburonosylhypoxanthine + 2 H(+)


name: H2O + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> H(+) + N-hexadecanoylethanolamine + sn-glycerol 3-phosphate


name: H2O + N(6)-acyl-L-lysyl-[protein] + NAD(+) = 2''-O-acyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: HYAL1 hydrolyses Chondroitin chains (Rattus norvegicus)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Bos taurus)


name: Cinaciguat binds sGC:NO (Drosophila melanogaster)


name: MAP2K1 phosphorylates MAPK3 (Rattus norvegicus)


name: 11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA


name: Activated NOD oligomer recruites RIP2 (RICK) (Canis familiaris)


name: a halide anion + glycolate + H(+) => a haloacetate + H2O


name: devancoaminyl-vancomycin + dTDP-beta-L-vancosamine = dTDP + epivancomycin + H(+)


name: [sulfur carrier]-SH + AH2 + N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine = 2-sulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + H(+) + L-methionine


name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Canis familiaris)


name: CO2(out) + H(+)(out) + ubiquinol-8 => formate(out) + 2 H(+)(in) + ubiquinone-8


name: (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+) => D-allo-isoleucine + H2O + O2


name: very-long-chain fatty acyl-CoA dehydrogenase activity


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + H(+) + phosphate


name: (4R)-hydroxysphinganine + 2-hydroxyhexacosanoyl-CoA = CoA + H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: USP30 deubiquitinates Ub-MOM proteins (Bos taurus)


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Danio rerio)


name: 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NADP(+) => 5alpha-cholest-8-en-3-one + CO2 + NADPH


name: SLC5A6 transports vitamins from extracellular region to cytosol (Homo sapiens)


name: Type X collagen associates with collagen type II fibrils (Rattus norvegicus)


name: UDP-glucose is oxidised to UDP-glucuronate (Drosophila melanogaster)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: Active ALK phosphorylates PLCG1 (Rattus norvegicus)


name: RIPK1 is cleaved by CASP8 (Mus musculus)


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 <=> 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + 2-oxoglutarate + H(+) + H2O => GDP-4-dehydro-alpha-D-rhamnose + L-glutamate


name: Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)


name: glyoxylate + L-leucine = 4-methyl-2-oxopentanoate + glycine


name: 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + beta-ionone => all-trans-10'-apo-beta-carotenal + O2


name: ROCK1,ROCK2 are activated (Homo sapiens)


name: Latent TGF-beta-1 is cleaved by FURIN (Gallus gallus)


name: 3,5-dihydroxybenzaldehyde + 4-hydroxybenzaldehyde => O2 + trans-resveratrol


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Sus scrofa)


name: MDM2 forms homo- or heterodimers (Canis familiaris)


name: USP10 deubiquitinates SNX3, CFTR (Gallus gallus)


name: Caspase mediated cleavage of vimentin at IDVD (259) (Homo sapiens)


name: CBL binds TGFBR2 (Drosophila melanogaster)


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Sus scrofa)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Sus scrofa)


name: CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Bos taurus)


name: D-glucose + sn-glycerol 3-phosphate <=> D-glucose 6-phosphate + glycerol


name: RUNX1 binds PRC1 complexes (Mus musculus)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + H2O <=> 2,4,5-trichlorocyclohexa-2,5-dien-1-ol + chloride + H(+)


name: H2O + S-benzyl-L-cysteinylglycine => glycine + S-benzyl-L-cysteine


name: ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1) (Homo sapiens)


name: 3-iodo-L-tyrosine + NADPH => iodide + L-tyrosine + NADP(+)


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-mannosamine <=> 3 H(+) + 2 NADH + UDP-N-acetyl-alpha-D-mannosaminouronate


name: RRAGA,B exchanges GDP for GTP (Canis familiaris)


name: Complement factor H binds to surface-bound C3b (Gallus gallus)


name: L-kynurenine transmembrane transporter activity


name: H2O + pristanoyl-CoA = 2,6,10,14-tetramethylpentadecanoate + CoA + H(+)


name: ATP + sedoheptulose => ADP + D-sedoheptulose 7-phosphate + H(+)


name: Activated FGFR1 binds PLCG1 (Xenopus tropicalis)


name: MAPKAPK2 phosphorylates HSF1 (Bos taurus)


name: RRAGC,D hydrolyzes GTP (Saccharomyces cerevisiae)


name: RHOD binds effectors at the endosome membrane (Schizosaccharomyces pombe)


name: PXLP-K333-GADL1 decarboxylates CSA to HTAU (Drosophila melanogaster)


name: H2O + N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] => H(+) + L-arginyl-[protein] + lactate


name: 2 H(+) + O2 + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H2O


name: (+)-valencene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (+)-nootkatone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: beta-D-mannopyranosyl-(1->2)-D-mannopyranose + phosphate = alpha-D-mannose 1-phosphate + D-mannose


name: 6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+) = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH


name: H2O + N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] = (S)-4,5-dihydroxy-2-oxopentanal + L-lysyl-[protein] + phosphate


name: n 3'-phosphoadenylyl sulfate + dermatan 4'-sulfate => n adenosine 3',5'-bisphosphate + dermatan 4',6'-bissulfate + n H(+)


name: STAB1 (FEEL-1) binds ligands (Mus musculus)


name: 4-isopropenyl-7-methyloxepan-2-one + H2O <=> 6-hydroxy-3-isopropenylheptanoate + H(+)


name: kaempferol 3-O-beta-D-glucoside + malonyl-CoA <=> CoA + kaempferol 3-O-(6-O-malonyl-beta-D-glucoside)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Bos taurus)


name: Association of gamma-H2AX with MCPH1 (Gallus gallus)


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine = H(+) + kanamycin X + UDP


name: PPT1 hydrolyses palmitoylated proteins (Dictyostelium discoideum)


name: Nociceptin receptor binds to nociceptin (Bos taurus)


name: adenosine(2085) in 23S rRNA + 2 S-adenosyl-L-methionine => 2 H(+) + N(6)-dimethyladenosine(2085) in 23S rRNA + 2 S-adenosyl-L-homocysteine


name: (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA => (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA


name: 2-oxoglutarate + D-alanine => D-glutamate + pyruvate


name: RHOBTB1 binds interacting proteins at the endosome membrane (Gallus gallus)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Drosophila melanogaster)


name: HEXA cleaves the terminal GalNAc from small HA fragments (Mus musculus)


name: (S)-cystathionine ketimine + 2 H(+) + NADH = (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NAD(+)


name: (3Z)-hex-3-en-1-ol + acetyl-CoA <=> (3Z)-hex-3-en-1-yl acetate + CoA


name: a 5'-hydroxy-3'-methoxyflavone + S-adenosyl-L-methionine = a 3',5'-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: 2xTNFR2 binds TNFA trimer:TNFR2 (Canis familiaris)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Sus scrofa)


name: (2E)-geraniol + benzoyl-CoA => (2E)-geranyl benzoate + CoA


name: (S)-1-pyrroline-5-carboxylate + H(+) + H2O => L-glutamate 5-semialdehyde


name: 2 Na(+)(out) + pyruvate(out) => 2 Na(+)(in) + pyruvate(in)


name: (24Z),26-hydroxydesmosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => desmosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate


name: Degradation of ubiquitinated SKI/SKIL (Danio rerio)


name: 4',7,8-trihydroxy-3'-methoxyflavone-7-olate + H(+) + S-adenosyl-L-homocysteine => 3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine


name: Ubiquitinated geminin is degraded by the proteasome (Gallus gallus)


name: Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Bos taurus)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> hapalindole H


name: a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H2O <=> a 3'-end 2'-deoxyribonucleotide-DNA + phosphate


name: Nitric oxide enters the bacterium (Homo sapiens)


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Drosophila melanogaster)


name: Phosphorylated MOB1A proteins associate with LATS proteins (Sus scrofa)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: a nucleoside + phosphate => a nucleoside 5'-phosphate + H2O


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O = [DsrC protein]-S-sulfo-L-cysteine/L-cysteine + 3 AH2 + H(+)


name: Transfer of Fe-S clusters to SDHB (Sus scrofa)


name: dUTP + 2 H2O <=> dUMP + 2 H(+) + 2 phosphate


name: L-glutaminyl-[protein] + serotonin <=> 5-serotonyl-L-glutamyl-[protein] + NH4(+)


name: TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 (Mus musculus)


name: Co(2+) + precorrin-2 => Co-precorrin-2 + 3 H(+)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Bos taurus)


name: n fibrin monomers -> fibrin multimer (Gallus gallus)


name: 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity


name: dimethylallyl diphosphate + L-glutamate => diphosphate + prekainate


name: H2O + N-(2-hydroxyhexacosanoyl)-sphinganine + NADP(+) => H(+) + N-hexacosanoylsphinganine + NADPH + O2


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O <=> (9Z,12Z)-octadecadienoate + di-(9Z,12Z)-octadecadienoylglycerol + H(+)


name: MK2 phosphorylates BRF1 (Rattus norvegicus)


name: L-aspartate(out) + L-phenylalanine(in) => L-aspartate(in) + L-phenylalanine(out)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Mus musculus)


name: Gq-BTK complex dissociates to Active BTK and Gq (Xenopus tropicalis)


name: Association of Emi1 with Cdh1 (Xenopus tropicalis)


name: TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4  (Rattus norvegicus)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Mus musculus)


name: Dissociation of the TP:Gq complex (Sus scrofa)


name: NADP(+) + prostaglandin D2 => 15-oxoprostaglandin D2 + H(+) + NADPH


name: adenosylcob(III)alamin 5'-phosphate + H2O = adenosylcob(III)alamin + phosphate


name: Formation of clathrin-coated vesicle (Homo sapiens)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Canis familiaris)


name: H(+) + NADPH + progesterone => 5beta-pregnan-3,20-dione + NADP(+)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Homo sapiens)


name: histamine transmembrane transporter activity


name: a 1-acylglycerone 3-phosphate + a long chain fatty alcohol => 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)


name: AMP + diphosphate + L-cysteinyl-tRNA(Cys) => ATP + L-cysteine + tRNA(Cys)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Xenopus tropicalis)


name: D-apiitol + NAD(+) => aldehydo-D-apiose + H(+) + NADH


name: SALM1 binds NMDA receptor (Homo sapiens)


name: atREs binds to nascent CM (Rattus norvegicus)


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Bos taurus)


name: CSNK1G2 phosphorylates p-CERT1-2 (Bos taurus)


name: (Z)-(4-hydroxyphenyl)acetaldehyde oxime = 4-hydroxyphenylacetonitrile + H2O


name: 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) = 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)


name: MAPKs phosphorylate ETS1 and ETS2 (Rattus norvegicus)


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Sus scrofa)


name: acetoacetyl-CoA + L-glutamate => (3S)-3-aminobutanoyl-CoA + 2-oxoglutarate


name: Formation of eEF1B complex (Homo sapiens)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Rattus norvegicus)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + CMP-N-acetyl-beta-neuraminate <=> 1,2-diacyl-3-[3-(N-acetyl-alpha-D-neuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+)


name: PGLYRP3,4 binds bacterial peptidoglycan (Drosophila melanogaster)


name: gibberellin A25,oxoglutarate:oxygen oxidoreductase activity


name: Formation of Cyclin A:Cdk2 complexes (Rattus norvegicus)


name: chloroacetate + 2 H(+) + NADPH => chloroacetaldehyde + H2O + NADP(+)


name: N-(2-hydroxy-hexanoyl)-sphinganine + UDP-alpha-D-galactose <=> H(+) + N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganine + UDP


name: OGG1beta translocates to mitochondria (Canis familiaris)


name: L-phenylalanine <=> (E)-cinnamate + NH4(+)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Caenorhabditis elegans)


name: Addition of GlcNAc to the glycan on the A arm (Danio rerio)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Saccharomyces cerevisiae)


name: Activated ATM phosphorylates DCLRE1C (Rattus norvegicus)


name: MT-MMPs are sorted to the plasma membrane (Homo sapiens)


name: Caspase-8 and FLIP(L) processing at TNFR signaling complex (Mus musculus)


name: Exocyst complex formation (Dictyostelium discoideum)


name: RBX1:CUL3 dissociates from forming autophagosome (Rattus norvegicus)


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Sus scrofa)


name: 12-hydroxy-(9E)-octadecenoate + phosphate => 12-phosphooxy-(9E)-octadecenoate + H2O


name: docosanoate + glycine = H2O + N-docosanoylglycine


name: ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Caenorhabditis elegans)


name: 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O => 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH


name: CYP19A1 hydroxylates TEST to EST17b (Drosophila melanogaster)


name: FOXM1 stimulates CDC25A transcription (Homo sapiens)


name: Release of acetylcholine at the synapse (Mus musculus)


name: MAF1 binds the PTEN gene promoter (Homo sapiens)


name: ATP + D-xylose(out) + H2O <=> ADP + D-xylose(in) + H(+) + phosphate


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)


name: Noradrenalin synaptic vesicle docking and priming (Drosophila melanogaster)


name: PIAS4 SUMOylates TOP2A with SUMO2,3 (Rattus norvegicus)


name: 14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD(+) = 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + H(+) + NADH


name: sucrose + H2O => glucose + fructose (Homo sapiens)


name: PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Sus scrofa)


name: activating MHC class Ib receptor activity


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4beta-methylzymosterol-4alpha-carboxylate + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: SLC26A3,6 exchange Cl- for HCO3- (Mus musculus)


name: Autophosphorylation and activation of CAMK2 (Mus musculus)


name: 3'-phosphoadenylyl sulfate + chenodeoxycholate = adenosine 3',5'-bisphosphate + chenodeoxycholate 7-sulfate + H(+)


name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Gallus gallus)


name: 27-hydroxycholesterol is 7alpha-hydroxylated (Rattus norvegicus)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] <=> 16alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + H2O + lipid A-core(in) <=> ADP + H(+) + lipid A-core(out) + phosphate


name: H2O + N-acetyl-D-glucosamino-1,5-lactone = H(+) + N-acetyl-D-glucosaminate


name: PRICKLE1 is degraded by the proteasome (Homo sapiens)


name: LC3 is cleaved by ATG4 (Dictyostelium discoideum)


name: PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)


name: a quinol + orotate => (S)-dihydroorotate + a quinone


name: Phosphorylation of APC component of the destruction complex (Mus musculus)


name: PHF20 binds TP53 dimethylated on K370 and K382 (Drosophila melanogaster)


name: USP18 binds IKBKG within IKK complex (Mus musculus)


name: H(+)(out) + nitrite(in) = H(+)(in) + nitrite(out)


name: (9Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: 9-(acyloxy)-octadecanoate + a 1-acyl-sn-glycerol => 9-hydroxy-octadecanoate + a 1,2-diacyl-sn-glycerol


name: Zinc is an agonist of GPR39 (Mus musculus)


name: Activated FGFR1 phosphorylates FRS3 (Danio rerio)


name: acetaldehyde + Co-precorrin-5B + H(+) => Co-precorrin-5A + H2O


name: RBKS phosphorylates ribose to R5P (Dictyostelium discoideum)


name: cortisone + H(+) + NADPH = cortisol + NADP(+)


name: ADP + H(+) + psi-UMP => ATP + pseudouridine


name: PTPN3 dephosphorylates MAPK12 (Caenorhabditis elegans)


name: GPIb:IX:V binds to VWF multimer:collagen (Mus musculus)


name: Recruitment of XPA and release of CAK  (Schizosaccharomyces pombe)


name: Active ALK phosphorylates IRS1 (Bos taurus)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-tetracosanoylsphinganine <=> a 1,2-diacyl-sn-glycerol + N-tetracosanoylsphinganine-(1D-myo-inositol)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate => (14S,15S)-epoxy-(5Z,8Z,10E,12E)-eicosatetraenoate + H2O


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Xenopus tropicalis)


name: BTG2 binds CCR4-NOT complex (Rattus norvegicus)


name: RFC binding displaces Pol Alpha (Sus scrofa)


name: 2 H(+)(out) + succinate(out) => 2 H(+)(in) + succinate(in)


name: aklavinone + NADP(+) = aklaviketone + 2 H(+) + NADPH


name: AMP + chenodeoxycholoyl-CoA + diphosphate => ATP + chenodeoxycholate + CoA


name: D-xylose(in) + H(+)(in) = D-xylose(out) + H(+)(out)


name: RHO1:GTP binds to activated DAAM (Drosophila melanogaster)


name: TBC1D20 binds RAB1:GTP (Plasmodium falciparum)


name: 1''-O-acetyl-ADP-alpha-D-ribose + H2O => acetate + ADP-D-ribose + H(+)


name: (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Rattus norvegicus)


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Drosophila melanogaster)


name: RAC1 binds effectors at the ER membrane (Xenopus tropicalis)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Drosophila melanogaster)


name: 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 = H2O + NADP(+) + neopentalenolactone D


name: Grb7 binds to the active PDGF receptor (Homo sapiens)


name: glycoursodeoxycholate + NADP(+) => 7-oxoglycolithocholate + H(+) + NADPH


name: H(+) + NADH + O2 + urate = 5-hydroxyisourate + H2O + NAD(+)


name: cytidine transmembrane transporter activity


name: Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it (Sus scrofa)


name: cyclo(L-phenylalanyl-L-leucyl) + O2 => cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2


name: MAP2K1 phosphorylates MAPK3 (Dictyostelium discoideum)


name: PK binds to VANG at the plasma membrane (Drosophila melanogaster)


name: NR3C1 binds NR3C1 agonists (Plasmodium falciparum)


name: 2-oxobutanoate + L-cysteine + NH4(+) => H2O + L,L-cystathionine


name: 5beta-pregnan-3,20-dione + NADP(+) => H(+) + NADPH + progesterone


name: p-MAPK2/3 phosphorylates HSP27 (Drosophila melanogaster)


name: TRiC/CCT binds unfolded G-protein beta subunit (Danio rerio)


name: PTPRJ dephosphorylates MET (Caenorhabditis elegans)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)


name: Canonical WNT signaling through the atypical receptor RYK (Gallus gallus)


name: Addition of nucleotides between position +11 and +30 (Mus musculus)


name: an aldehyde + 2 Fe(II)-[cytochrome cL] + 2 H(+) => a primary alcohol + 2 Fe(III)-[cytochrome cL]


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Drosophila melanogaster)


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Caenorhabditis elegans)


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Rattus norvegicus)


name: miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2 H(+) + 3 H2O + miltiradien-20-al + 2 oxidized [NADPH--hemoprotein reductase]


name: (9Z)-hexadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-hexadecenyl (9Z)-octadecenoate + CoA


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)


name: (1S,3R,5S)-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH


name: Exocytosis of platelet dense granule content (Drosophila melanogaster)


name: a ganglioside GD1a (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD1a (d18:1(4E)) + CoA


name: ABL1 phosphorylates YAP1 (Rattus norvegicus)


name: PP2A mediated localization of RB1 protein in chromatin (Homo sapiens)


name: H(+) + H2O + N-isopropylammelide <=> cyanurate + isopropylamine


name: PB1-F2 binds to the mitochondrial adenine nucleotide translocator 3 ANT3, inducing apoptosis (Homo sapiens)


name: a cardiolipin + CMP + H(+) => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a CDP-1,2-diacyl-sn-glycerol


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Mus musculus)


name: Formation of RAD52 heptameric ring structure complexes (Dictyostelium discoideum)


name: (E)-caffeoyl-CoA + H2O <=> 3-hydroxy-3-(3,4-dihydroxyphenyl)propanoyl-CoA


name: KDM5A-D demethylate Me3K5-histone H3 (Dictyostelium discoideum)


name: BTNL2 binds activated T cells surface (Rattus norvegicus)


name: NTN4 binds laminins with gamma-1, gamma-3 (Homo sapiens)


name: NR1D1 (REV-ERBA) binds heme, the PPARGC1A gene, and recruits corepressors (Homo sapiens)


name: PDGF binds to extracellular matrix proteins (Canis familiaris)


name: 2-oxoglutarate + O2 + validamycin A => CO2 + H(+) + succinate + validamycin B


name: fumarate(in) + L-aspartate(out) => fumarate(out) + L-aspartate(in)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Dictyostelium discoideum)


name: (Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 = (-)-4'-methoxycyclopenine + CO2 + succinate


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Drosophila melanogaster)


name: Dephosphorylation of PAG by SHP2 (Sus scrofa)


name: Soluble guanylate cyclase converts GTP to cGMP (Homo sapiens)


name: BAD displaces tBID from BCL-2 sequestration (Canis familiaris)


name: 3-amino-4-hydroxybenzoate + acetyl-CoA <=> 3-acetylamino-4-hydroxybenzoate + CoA


name: dibenzothiophene sulfone monooxygenase (NADH) activity


name: H2O + N(tele)-phospho-L-histidyl-[protein] <=> L-histidyl-[protein] + phosphate


name: a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 (d18:1(4E)) + H(+) + UDP


name: SUMOylation of NPM1 with SUMO1 (Homo sapiens)


name: MKRN1 polyubiquitinates PTEN (Canis familiaris)


name: Dephosphorylation of phospho-Cdh1 (Saccharomyces cerevisiae)


name: atROL binds RBP1 (parenchymal cell) (Sus scrofa)


name: H2O + L-homocysteine <=> 2-oxobutanoate + H(+) + hydrogen sulfide + NH4(+)


name: Interaction of PAK1 with Rac1-GTP (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + isoelisabethatriene


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Rattus norvegicus)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Bos taurus)


name: kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin (Rattus norvegicus)


name: FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling (Canis familiaris)


name: ADP + dapdiamide E + H(+) + phosphate => 3-[[[(2R,3R)-3-carboxyoxiran-2-yl]carbonyl]amino]-L-alanine + ATP + L-valine


name: (6S)-5,6,7,8-tetrahydrofolate + S,S-dimethyl-beta-propiothetin = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 3-(methylsulfanyl)propanoate + H(+)


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Dictyostelium discoideum)


name: an N(4)-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in rRNA + S-adenosyl-L-methionine


name: Release of SMAC (DIABLO) from mitochondria (Bos taurus)


name: Translocation of BIM to mitochondria (Canis familiaris)


name: SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Homo sapiens)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Plasmodium falciparum)


name: 3'-phosphoadenylyl sulfate + a 12-hydroxyjasmonate <=> a 12-sulfojasmonate + adenosine 3',5'-bisphosphate + H(+)


name: TRAF6 polyubiquitinates NRIF (Canis familiaris)


name: RB1 translocates to the nucleus (Canis familiaris)


name: AH2 + kynurenate + O2 => 7,8-dihydro-7,8-dihydroxykynurenate + A


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Sus scrofa)


name: chloride(in) + creatine(in) + 2 Na(+)(in) => chloride(out) + creatine(out) + 2 Na(+)(out)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + NAD(+) <=> 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + NADH


name: butanoate(in) + dehydroepiandrosterone 3-sulfate(out) => butanoate(out) + dehydroepiandrosterone 3-sulfate(in)


name: Retromer associates with WLS (Homo sapiens)


name: L-histidyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine


name: FPGS-2 transforms THF to THFPG (Danio rerio)


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Drosophila melanogaster)


name: Basigin binds Mannose-carrying cell recognition molecules (Xenopus tropicalis)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Bos taurus)


name: decane + O2 + reduced [NADPH--hemoprotein reductase] <=> 3-decanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TFIIH binds GG-NER site to form a verification complex (Dictyostelium discoideum)


name: ATP + cadaverine + L-glutamate <=> ADP + gamma-L-glutamylcadaverine + H(+) + phosphate


name: 6-diphospho-1D-myo-inositol pentakisphosphate + H2O <=> 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: NADH + 2 oxidized [cytochrome P450] = H(+) + NAD(+) + 2 reduced [cytochrome P450]


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Plasmodium falciparum)


name: E2F6 binds the PRC1 complex (Xenopus tropicalis)


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Xenopus tropicalis)


name: 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide + NADP(+) <=> H(+) + momilactone A + NADPH


name: RP2:ARL3:GDP:UNC119B dissociates (Canis familiaris)


name: p-T774-PKN1 phosphorylates CDC25C (Homo sapiens)


name: GP1b-IX-V binds 14-3-3-zeta (Bos taurus)


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Bos taurus)


name: NFE2L2 binds CREBBP,EP300 (Drosophila melanogaster)


name: H(+) + hexadecanoate + NADPH + O2 = 15-hydroxyhexadecanoate + H2O + NADP(+)


name: NFkB dependent NFE2L2 expression (Homo sapiens)


name: ATP + glycine betaine(out) + H2O <=> ADP + glycine betaine(in) + H(+) + phosphate


name: beta-alanyl-L-lysine + H2O => beta-alanine + L-lysine


name: F2R:ARRB1 binds MAPKs, SRC-1 (Bos taurus)


name: (E)-coniferyl acetate + NADPH => acetate + eugenol + NADP(+)


name: 2-oxoglutarate(in) + taurocholate(out) = 2-oxoglutarate(out) + taurocholate(in)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Schizosaccharomyces pombe)


name: pyruvate + NADH + H+ <=> lactate + NAD+ (Gallus gallus)


name: bilirubin transmembrane transporter activity


name: VANG, IN, FY, and FRTZ colocalise at the plasma membrane (Drosophila melanogaster)


name: COMT transfers Met to DOPAC to form HVA (Bos taurus)


name: chloride(out) + 2 hydrogencarbonate(in) + K(+)(in) = chloride(in) + 2 hydrogencarbonate(out) + K(+)(out)


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Homo sapiens)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Bos taurus)


name: D-glucose 6-phosphate + NAD(+) = 3-dehydro-D-glucose 6-phosphate + H(+) + NADH


name: (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin <=> GMP + H(+) + oxidized coenzyme F420-0


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Rattus norvegicus)


name: TTLLs polyglutamylate tubulin (Canis familiaris)


name: a ketone + reduced coenzyme F420-(gamma-L-Glu)(n) => a secondary alcohol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Homo sapiens)


name: (22R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (22R,7alpha)-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cAMP binds PKA tetramer (Schizosaccharomyces pombe)


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Danio rerio)


name: (2E)-hexacosenoyl-CoA + H2O => (3R)-hydroxyhexacosanoyl-CoA


name: MITF-M-dependent IRF4 gene expression (Homo sapiens)


name: IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation  (Drosophila melanogaster)


name: STAT1 and STAT3 dimers translocate to the nucleus (Homo sapiens)


name: N-terminal glycyl-[protein] + tetradecanoyl-CoA <=> CoA + H(+) + N-tetradecanoylglycyl-[protein]


name: Factor IIa inhibitors (compounds) binds IIa (Rattus norvegicus)


name: a 1,3-diacyl-sn-glycerol + an acyl-CoA <=> a triacyl-sn-glycerol + CoA


name: 2-oxoglutarate + gibberellin A1 + O2 => CO2 + gibberellin A8 + succinate


name: a monoacylglycerol + ATP <=> ADP + H(+) + monoacyl-sn-glycero-3-phosphate


name: Formation of the Spliceosomal P complex and exon ligation (Rattus norvegicus)


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Homo sapiens)


name: DLST transfers succinyl to CoA (Saccharomyces cerevisiae)


name: SCD desaturates ST-CoA to OLE-CoA (Danio rerio)


name: [protein]-D-aspartate + S-adenosyl-L-methionine <=> [protein]-D-aspartate methyl ester + S-adenosyl-L-homocysteine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+)


name: MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) (Dictyostelium discoideum)


name: Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Homo sapiens)


name: 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] <=> 17beta,18-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Gamma-secretase cleaves YBX1:NOTCH3 (Xenopus tropicalis)


name: 2-oxoglutarate(out) + urate(in) <=> 2-oxoglutarate(in) + urate(out)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + H2O <=> H(+) + hexadecanoate + sn-glycerol 3-phosphate


name: 2-demethylmenaquinol-8 + H(+) + trimethylamine N-oxide => 2-demethylmenaquinone-8 + H2O + trimethylamine


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Canis familiaris)


name: Phosphorylation of USP8 by P-AKT (Mus musculus)


name: 2-dehydro-3-deoxy-D-arabinonate + NAD(+) => 5-hydroxy-2,4-dioxopentanoate + H(+) + NADH


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Bos taurus)


name: VRK1/VRK2 phosphorylate BANF1 (Rattus norvegicus)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Canis familiaris)


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Canis familiaris)


name: oxaloacetate(out) + sulfate(in) => oxaloacetate(in) + sulfate(out)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Plasmodium falciparum)


name: H2O + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] = 3-deoxyglucosone + L-lysyl-[protein] + phosphate


name: RHOQ GAPs stimulate RHOQ GTPase activity (Schizosaccharomyces pombe)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Gallus gallus)


name: cis-trans-nepetalactol + NAD(+) <=> cis-trans-nepetalactone + H(+) + NADH


name: Aquaporins passively transport urea out of cells (Rattus norvegicus)


name: GPIHBP1 binds HSPG:LPL dimer (Bos taurus)


name: CoA + H(+) + N(1)-acetylspermine => acetyl-CoA + spermine


name: PLC beta-mediated PIP2 hydrolysis (Drosophila melanogaster)


name: a secondary alcohol + NAD(+) = a ketone + H(+) + NADH


name: H(+) + NADH + O2 + protoasukamycin <=> 4-hydroxyprotoasukamycin + H2O + NAD(+)


name: Mitochondrial recruitment of Drp1 (Schizosaccharomyces pombe)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Homo sapiens)


name: streptothricin F acid => H2O + streptothricin F


name: HDACs deacetylate p-STAT3 dimers (Bos taurus)


name: (E)-prop-1-en-1-SO-peroxol => (Z)-propanethial S-oxide


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: (11Z)-eicosenoyl-CoA + H(+) + malonyl-CoA <=> (13Z)-3-oxodocosenoyl-CoA + CO2 + CoA


name: (2E,6E)-farnesyl diphosphate + H2O => (6E)-nerolidol + diphosphate


name: Basigin binds Mannose-carrying cell recognition molecules (Rattus norvegicus)


name: beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (5R,6S)-5,6-epoxi-beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Homo sapiens)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Mus musculus)


name: a globoside Gb4Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a globoside Forssman (d18:1(4E)) + H(+) + UDP


name: Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex (Sus scrofa)


name: ADP + H(+) + monoacyl-sn-glycero-3-phosphate => a monoacylglycerol + ATP


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Caenorhabditis elegans)


name: Deacetylation of cleaved cohesin (Sus scrofa)


name: 11beta,17beta-dihydroxyandrost-4-ene-3-one + NAD(+) => 17beta-hydroxyandrost-4-ene-3,11-dione + H(+) + NADH


name: Glutamine transport from astrocytes (Rattus norvegicus)


name: D-maltohexaono-1,5-lactone + H2O2 => D-maltohexaose + O2


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 => 1-O-methyl-(13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Sus scrofa)


name: acetyl-CoA + eicosanoyl-CoA = 3-oxodocosanoyl-CoA + CoA


name: H(+) + N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine


name: (7S)-salutaridinol + NADP(+) => H(+) + NADPH + salutaridine


name: CDP-DAG is converted to PI by CDIPT (Homo sapiens)


name: Collagen type I binds integrin alpha1beta1, alpha2beta1, alpha10beta1 (Homo sapiens)


name: 2,3-dihydroxybenzoate + O2 <=> 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)


name: 3-dehydro-4-O-phospho-L-erythronate + H(+) => CO2 + dihydroxyacetone phosphate


name: ATP + hydrogencarbonate + propanoyl-CoA = ADP + H(+) + methylmalonyl-CoA + phosphate


name: FAICAR => IMP + H2O (Dictyostelium discoideum)


name: 17-hydroxy-3-oxochol-4-en-22-oyl-CoA => 3-oxochola-4,17-dien-22-oyl-CoA + H2O


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Rattus norvegicus)


name: CTP + 2 H2O = CMP + 2 H(+) + 2 phosphate


name: 10-deoxymethynolide + dTDP-alpha-D-desosamine => 10-deoxymethymycin + dTDP + H(+)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Canis familiaris)


name: neamine + UDP-alpha-D-kanosamine <=> H(+) + kanamycin B + UDP


name: SREBP1A,1C,2 binds Importin beta-1 (Mus musculus)


name: Association of Cdh1 with the APC/C (Homo sapiens)


name: Nuclear transport of pChREBP (Thr 666) protein (Homo sapiens)


name: GBF1 recruits ARF:GDP to the Golgi (Drosophila melanogaster)


name: Regulation of KIF20A (MKL2) by phosphorylation (Drosophila melanogaster)


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Release of SMAC (DIABLO) from mitochondria (Mus musculus)


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Mus musculus)


name: SUMOylation of NOP58 with SUMO1 (Caenorhabditis elegans)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Dictyostelium discoideum)


name: PPP5C dephosphorylates TP53BP1 (Bos taurus)


name: Hydrolysis of choloyl-CoA to cholate and CoASH (Xenopus tropicalis)


name: 2-acyl LPE is acylated to PE by LPEAT (Caenorhabditis elegans)


name: 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide => H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+)


name: ADA catalyzes the deamination of (deoxy)adenosine (Rattus norvegicus)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Rattus norvegicus)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Canis familiaris)


name: PTPN22 dephosphorylates ZAP70 (Gallus gallus)