name: a long-chain fatty acyl-CoA(in) => a long-chain fatty acyl-CoA(out)


name: PHF8 demethylates MeK21-histone H4 (Caenorhabditis elegans)


name: Mcm4,6,7 trimer forms and associates with the replication fork (Schizosaccharomyces pombe)


name: FAR2 reduces PalmCoA to HXOL (Caenorhabditis elegans)


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Bos taurus)


name: FLVCR1-1 transports heme from cytosol to extracellular region (Mus musculus)


name: butan-1-ol + hexanoyl-CoA <=> butyl hexanoate + CoA


name: SLITs bind keratan sulfate (Caenorhabditis elegans)


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Mus musculus)


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Caenorhabditis elegans)


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Displacement of TDG glycosylase by APEX1 at the AP site (Homo sapiens)


name: alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O => alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate + H(+)


name: (S)-cis-N-methyltetrahydrothalifendine + O2 + reduced [NADPH--hemoprotein reductase] <=> 7-hydroxy-8-methoxy-11-methyl-17,19-dioxa-11-azatetracyclo[12.7.0.0(4,9).0(16,20)]henicosa-1(21),4(9),5,7,14,16(20)-hexaen-2-one + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: hydrogencarbonate(in) + Na(+)(in) = hydrogencarbonate(out) + Na(+)(out)


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 20S,25-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: 2 Na(+)(out) + uridine(out) <=> 2 Na(+)(in) + uridine(in)


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Sus scrofa)


name: gap junction channel activity involved in cardiac conduction electrical coupling


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Sus scrofa)


name: catechol + H2O + NADP(+) => H(+) + NADPH + O2 + phenol


name: ATP + H2O + taurochenodeoxycholate(in) => ADP + H(+) + phosphate + taurochenodeoxycholate(out)


name: glyphosate + H2O + O2 <=> aminomethylphosphonate + glyoxylate + H(+) + H2O2


name: SFTPD binds with itself to form SFTPD 12mer (Plasmodium falciparum)


name: kaempferol + S-adenosyl-L-methionine <=> H(+) + kaempferide + S-adenosyl-L-homocysteine


name: luteolin + S-adenosyl-L-methionine = H(+) + luteolin 7-methyl ether + S-adenosyl-L-homocysteine


name: Formation Of Bloc-1 Complex (Sus scrofa)


name: MDM2 ubiquitinates DYRK2 (Rattus norvegicus)


name: L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Mus musculus)


name: FLIP(L) and procaspase-8 form heterodimer (Mus musculus)


name: (Z)-3-hydroxypropyl glucosinolate + H2O <=> (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Sus scrofa)


name: propanoyl-CoA + succinate = propanoate + succinyl-CoA


name: PAKs phosphorylate MLC (Rattus norvegicus)


name: (2E,11Z)-eicosadienoyl-CoA + H(+) + NADPH <=> (11Z)-eicosenoyl-CoA + NADP(+)


name: 3-oxo-2-methylhexadecanoyl-CoA + CoA => propanoyl-CoA + tetradecanoyl-CoA


name: Dephosphorylation of STAT1 by SHP2 (Canis familiaris)


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Dictyostelium discoideum)


name: 5-methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)


name: alpha-NAD(+) + H2O = ADP-D-ribose + H(+) + nicotinamide


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Rattus norvegicus)


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA => (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O


name: (2Z,6Z)-farnesyl diphosphate <=> (Z)-beta-farnesene + diphosphate


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Sus scrofa)


name: NADPH reduces NDOR1:CIAPIN1 (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + sitosterol <=> (22S)-22-hydroxysitosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + NAD(+) + nitrite => H(+) + NADH + nitrate


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Bos taurus)


name: 3-dehydro-6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 3-dehydroteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine => D-histidine + S-adenosyl-L-methionine


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Gallus gallus)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Canis familiaris)


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Drosophila melanogaster)


name: COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates (Bos taurus)


name: UDP-alpha-D-glucuronate + zolasartan = UDP + zolarsartan O-beta-D-glucuronoside


name: Expression of ABCG5 regulated by NR1H2,3 (Homo sapiens)


name: POLZ elongates POLI-incorporated dNMP (Sus scrofa)


name: D-cellopentaono-1,5-lactone + H2O <=> D-cellopentaonate + H(+)


name: PKC phosphorylates NCF1 (Saccharomyces cerevisiae)


name: ARL6:GTP and the BBSome bind ciliary cargo (Gallus gallus)


name: H(+)(out) + novobiocin(in) <=> H(+)(in) + novobiocin(out)


name: Activated CEBPB binds CDKN2B promoter (Homo sapiens)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Drosophila melanogaster)


name: SUMOylation of HDAC1 with SUMO1 (Homo sapiens)


name: Trimerization of HSF1 in the nucleus (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate


name: Binding of cAMP to HCN channels (Mus musculus)


name: 5-dehydro-D-fructose + AH2 => A + keto-L-sorbose


name: NADP(+) + tetrahydrocurcumin <=> dihydrocurcumin + H(+) + NADPH


name: 1-octadecanoyl-sn-glycero-3-phosphate + choline + H(+) => 1-octadecanoyl-sn-glycero-3-phosphocholine + H2O


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Bos taurus)


name: (2Z,6Z)-farnesyl diphosphate = alpha-acoradiene + diphosphate


name: precorrin-2 + S-adenosyl-L-methionine = H(+) + precorrin-3A + S-adenosyl-L-homocysteine


name: 7-isopropyl-4-methyloxepan-2-one + H2O <=> 6-hydroxy-3,7-dimethyloctanoate + H(+)


name: L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH


name: NR1D1 (REV-ERBA) binds heme, the ARNTL gene, and recruits corepressors. (Homo sapiens)


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Homo sapiens)


name: B3GAT dimers transfer GlcA to tetrasaccharide linker (Drosophila melanogaster)


name: 8-oxocoformycin + H(+) + NADPH => coformycin + NADP(+)


name: 2-oxoaldehyde + H2O + NADP(+) = a 2-oxocarboxylate + 2 H(+) + NADPH


name: PXLP-K212-CTH cleaves L-Cystathionine (Homo sapiens)


name: (3Z)-hex-3-en-1-yl acetate + CoA => (3Z)-hex-3-en-1-ol + acetyl-CoA


name: 3''-O-acetyl-ADP-D-ribose + H2O = acetate + ADP-D-ribose + H(+)


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate => (9Z,12Z)-octadecadienoate + O2


name: acetyl-CoA + octopamine = CoA + H(+) + N-acetyloctopamine


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate <=> an alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate


name: Dimerization of LIMK1 by Hsp90 (Rattus norvegicus)


name: AKT phosphorylates FOXO transcription factors (Gallus gallus)


name: (7R,8S)-7,8-diammoniononanoate + CO2 => (7R,8S)-8-amino-7-(carboxyamino)nonanoate + 2 H(+)


name: BH2 binding can lead to eNOS uncoupling (Rattus norvegicus)


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Gallus gallus)


name: MAP2K2 phosphorylates MAPK1 (Canis familiaris)


name: a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+) => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Gallus gallus)


name: SMO translocates to the cilium (Sus scrofa)


name: 7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA <=> 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + ADP + H(+)


name: estrone 3-sulfate(out) + n H(+)(out) = estrone 3-sulfate(in) + n H(+)(in)


name: SLC12A3 binds SLC12A3 inhibitors (Bos taurus)


name: 1-octanoyl-sn-glycero-3-phosphocholine <=> 1-octanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: a 1,2-diacylglycerol + a 1-acylglycerol = a triacylglycerol + glycerol


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + H2O <=> 1-O-hexadecyl-sn-glycerol + acetate + H(+)


name: Conversion of C2 into C2a and C2b (Canis familiaris)


name: (S)-2-amino-6-oxohexanoate + guanidine => 6-hydroxy-L-homoarginine


name: insulin-responsive glucose:proton symporter activity


name: CASP9 is phosphorylated at T412 (Rattus norvegicus)


name: lutein + O2 = (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R,6R)-hydroxy-alpha-ionone


name: MRN activates ATM (Drosophila melanogaster)


name: (E)-feruloyl-CoA + AMP + diphosphate => (E)-ferulate + ATP + CoA


name: PRKAA2 regulated nuclear export of NFE2L2 (Drosophila melanogaster)


name: TPI1 isomerizes GA3P to DHAP (Homo sapiens)


name: 3-dehydro-15-methylhexadecasphinganine + H(+) + NADPH => 15-methylhexadecasphinganine + NADP(+)


name: TRAF6 is auto-ubiquitinated (Homo sapiens)


name: Autoglucosylation of GYG2 complexed with GYS2-b (Dictyostelium discoideum)


name: (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glutathione => (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate


name: 5,10-methylenetetrahydromethanopterin + glycine + H2O <=> 5,6,7,8-tetrahydromethanopterin + L-serine


name: Cytoslic carboxylases translocate to mitochondrial matrix (Homo sapiens)


name: Urotensin-2 receptor binds urotensin-2 and 2B (Mus musculus)


name: p-PKR dimer phosphorylates CDK1 (Sus scrofa)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Rattus norvegicus)


name: SDHAF4 binds to FAD-SDHA (Drosophila melanogaster)


name: 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + H(+) + NADPH + O2 => 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + 2 H2O + NADP(+)


name: Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)


name: NADP(+) + raucaffrinoline = H(+) + NADPH + perakine


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Sus scrofa)


name: bacteriochlorophyll a + 3 NADP(+) <=> geranylgeranyl-bacteriochlorophyllide a + 3 H(+) + 3 NADPH


name: Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind PLCG1 (Homo sapiens)


name: RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Saccharomyces cerevisiae)


name: alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity


name: 4-imidazolone-5-propanoate => H2O + trans-urocanate


name: 1H-imidazole + acetyl-CoA <=> CoA + N-acetylimidazole


name: 2-deoxy-alpha-D-ribose 1-phosphate + guanine => 2'-deoxyguanosine + phosphate


name: 2-glyceryl-prostaglandin H2 <=> 2-glyceryl-prostaglandin E2


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Mus musculus)


name: (2E)-geranyl diphosphate + esculetin => 8-geranylesculetin + diphosphate


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 <=> (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate


name: an N-carbamoyl-L-alpha-amino acid + 2 H(+) + H2O = an L-alpha-amino acid + CO2 + NH4(+)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Saccharomyces cerevisiae)


name: 2-cis-(+)-abscisate + O2 + reduced [NADPH--hemoprotein reductase] => (+)-8'-hydroxyabscisate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 17alpha-estradiol + UDP-alpha-D-glucuronate <=> 17alpha-estradiol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: 2-methylbutanoyl-CoA + AMP + diphosphate => 2-methylbutanoate + ATP + CoA


name: D-fructopyranose(out) + Na(+)(out) = D-fructopyranose(in) + Na(+)(in)


name: Unknown NAT N-acylates Gly in GNAT1 (Homo sapiens)


name: H2O + N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein] = glycolate + H(+) + L-arginyl-[protein]


name: beta-D-fructose 6-phosphate + diphosphate => beta-D-fructose 1,6-bisphosphate + H(+) + phosphate


name: 1-acyl LPE is acylated to PE by LPEAT (Dictyostelium discoideum)


name: (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O = 2-oxopent-4-enoate + formate + H(+)


name: ADAMTS13 cleaves VWF multimer (Sus scrofa)


name: 2-dehydro-D-glucose + L-phenylalanine => (2S)-3-phenyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O


name: 2-oxoglutarate + dTDP-3-amino-3,6-dideoxy-alpha-D-glucose => dTDP-3-dehydro-6-deoxy-alpha-D-glucose + L-glutamate


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Drosophila melanogaster)


name: botB LC cleaves target cell VAMP2 (Homo sapiens)


name: L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate


name: 3 Na(+)(out) + succinate(out) = 3 Na(+)(in) + succinate(in)


name: biotin(out) + 2 Na(+)(out) <=> biotin(in) + 2 Na(+)(in)


name: E-cadherin degradation by ADAM10, ADAM15 (Bos taurus)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline <=> 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: [phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine <=> [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine


name: H(+)(out) + nitrite(in) <=> H(+)(in) + nitrite(out)


name: coelenterazine + O2 = CO2 + coelenteramide + hnu


name: RUNX3 binds SMAD3 and SMAD4 (Sus scrofa)


name: diphosphate + glycerol => glycerol 1-phosphate + H(+) + phosphate


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Sus scrofa)


name: dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 3 H2O + 2 NADP(+) => dTDP-beta-L-evernosamine + H(+) + 2 NADPH + 2 O2


name: DFF dissociates from importin-alpha:importin-beta (Drosophila melanogaster)


name: SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)


name: Glucosylation of collagen propeptide hydroxylysines (Drosophila melanogaster)


name: H2O + kojibiose => beta-D-glucose + D-glucose


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Xenopus tropicalis)


name: ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Dictyostelium discoideum)


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Gallus gallus)


name: MBTPS1 (S1P) cleaves CREB3L3 (Mus musculus)


name: PDGF-AB clevage by Furin (Caenorhabditis elegans)


name: PP2A dephosphorylates BANF1 (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 <=> prostaglandin G2


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Schizosaccharomyces pombe)


name: D-glucose 6-phosphate + NADP(+) <=> 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH


name: (4S)-4-hydroxy-L-glutamate + 2-oxoglutarate <=> (4R)-4-hydroxy-2-oxoglutarate + L-glutamate


name: a 2-oxocarboxylate + L-alanine = an L-alpha-amino acid + pyruvate


name: (9Z)-octadecenoyl-CoA + dopamine <=> CoA + H(+) + N-(9Z-octadecanoyl)-dopamine


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Drosophila melanogaster)


name: gibberellin A12 aldehyde + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => ent-7alpha-hydroxykaur-16-en-19-oate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Interaction of DAP12 and TREM1 (Canis familiaris)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Rattus norvegicus)


name: SRC-1 phosphorylates SHB (Canis familiaris)


name: acetaldehyde + H(+) + NADH => ethanol + NAD(+)


name: (6S)-NADPHX + ATP => ADP + H(+) + NADPH + phosphate


name: mesaconate + succinyl-CoA <=> 2-methylfumaryl-CoA + succinate


name: TPMT transfers methyl group to 6TIMP, forming 6MeTIMP (Rattus norvegicus)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Saccharomyces cerevisiae)


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-alpha-D-galactose = H(+) + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP


name: GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a (Drosophila melanogaster)


name: ATP + CoA + glutarate => ADP + glutaryl-CoA + phosphate


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Mus musculus)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Mus musculus)


name: ABCA12 transports lipids from cytosol to extracellular region (Gallus gallus)


name: coproporphyrin I(in) => coproporphyrin I(out)


name: 4-coumaroyl-CoA + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside <=> a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA


name: Fe(III)-{di[N-(2,3-dihydroxybenzoyl)-L-seryl]-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + H(+) => Fe(III)-C-5-deoxy-beta-D-glucosyl-enterobactin + H2O


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Bos taurus)


name: 2,5-dioxovalerate dehydrogenase (NAD+) activity


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Saccharomyces cerevisiae)


name: a 7-methoxyisoflavone + H(+) + S-adenosyl-L-homocysteine => a 7-hydroxyisoflavone + S-adenosyl-L-methionine


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Schizosaccharomyces pombe)


name: 5-aminolevulinate + pyruvate => 4,5-dioxopentanoate + L-alanine


name: CHUK, IKBKB phosphorylate RIPK1 at S25 (Rattus norvegicus)


name: CoA + zymosterol ester => an acyl-CoA + zymosterol


name: PSAP(195-273) dimer binds PE (Caenorhabditis elegans)


name: AKR1C3 reduces atRAL to atROL (Drosophila melanogaster)


name: PTK2 autophosphorylates downstream of EGFR (Mus musculus)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Dictyostelium discoideum)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-valine + O2 => 2-dehydro-D-glucose + H2O2 + L-valine


name: heptadecasphing-4-enine + octadecanoyl-CoA = CoA + H(+) + N-octadecanoyl-heptadecasphing-4-enine


name: Nck binds to the active PDGF receptor (Rattus norvegicus)


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Xenopus tropicalis)


name: alpha-maltohexaose + phosphate = alpha-D-glucose 1-phosphate + alpha-maltopentaose


name: H2O + methylenediurea <=> N-(carboxyaminomethyl)urea + NH4(+)


name: IL22 binds IL22RA1:JAK1 receptor complex (Bos taurus)


name: TLR9 processing at neutral pH (Homo sapiens)


name: DOLK phosphorylates DCHOL to DOLP (Drosophila melanogaster)


name: RAB43 hydrolyses GTP (Schizosaccharomyces pombe)


name: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2


name: Association of APOBEC3G:Vif with the Cul5-SCF complex (Homo sapiens)


name: alpha-D-xylose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-xylose


name: (2R)-2-hydroperoxytetradecanoate => O2 + tetradecanoate


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Rattus norvegicus)


name: 3-oxosphinganine + octanoyl-CoA <=> CoA + H(+) + N-octanoyl-3-oxosphinganine


name: POLK incorporates dNMP opposite to damaged DNA base (Dictyostelium discoideum)


name: ABCA4 mediates atRAL transport (Bos taurus)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b (Homo sapiens)


name: LTA4 is hydolysed to LTB4 by LTA4H (Dictyostelium discoideum)


name: Full-length SNK is cleaved by GD serine protease (Drosophila melanogaster)


name: NH4(+) + phenol + pyruvate => H2O + L-tyrosine


name: POLB-mediated DNA strand displacement synthesis (Rattus norvegicus)


name: 2-oxoglutarate + L-arginyl-[protein] + O2 = (3R)-3-hydroxy-L-arginyl-[protein] + CO2 + succinate


name: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]-[ferredoxin] + 2 phosphate => 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe-4S]-[ferredoxin]


name: 6-phospho-D-gluconate + NADP(+) = 6-phospho-2-dehydro-D-gluconate + H(+) + NADPH


name: RAC1 binds effectors at the plasma membrane (Sus scrofa)


name: RAC1:GTP:FMNL1 binds profilin:G-actin (Homo sapiens)


name: 3-{[(1S,2R,4aR,6R,8aS)-2-(but-2-en-2-yl)-3,4a,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-5-(2-methylpropyl)-2,3-dihydro-1H-pyrrol-2-one + O2 = H2O2 + myceliothermophin E


name: CoA + H(+) + N-acyl-3-oxosphinganine => 3-oxosphinganine + a fatty acyl-CoA


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Plasmodium falciparum)


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Canis familiaris)


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Homo sapiens)


name: Phosphorylation of BTK by p-SYK (Gallus gallus)


name: acetyl-CoA + D-glutamine => CoA + H(+) + N-acetyl-D-glutamine


name: H2O + L-xylono-1,4-lactone = H(+) + L-xylonate


name: 3-octadecanoyl-sn-glycero-1-phospho-(3'-octadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol) => 2 3-octadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol)


name: (2E,6E)-farnesyl diphosphate <=> (-)-alpha-amorphene + diphosphate


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Homo sapiens)


name: RAC3 translocates to the endoplasmic reticulum membrane (Gallus gallus)


name: (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+) => (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA + H(+) + NADPH


name: 13-dihydrocarminomycin + H(+) + NADPH + O2 => carminomycin + 2 H2O + NADP(+)


name: MSRA reduces L-methyl-(S)-S-oxide to L-Methionine (Bos taurus)


name: (+)-dehydrodiconiferyl acid + a quinone = (+)-dehydrodiconiferyl acid ketone + a quinol


name: P2Y9 receptor can bind to LPA (Mus musculus)


name: CREB3L3 translocates from the cytosol to the nucleus (Sus scrofa)


name: lipid A-core heptosyltransferase activity


name: decane + O2 + reduced [NADPH--hemoprotein reductase] => 3-decanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Fibrillin-1 binds latent TGF-beta (Canis familiaris)


name: H(+) + red chlorophyll catabolite => epoxypheophorbide a + H2O


name: a 3-(acyloxy)acyl derivative of bacterial toxin + H2O => 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)


name: 2xTPK1:Mg2+ phosphorylates THMN (Saccharomyces cerevisiae)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Saccharomyces cerevisiae)


name: H2O + uridine 2'-phosphate <=> phosphate + uridine


name: H2O + succinyl-CoA => CoA + H(+) + succinate


name: Association of beta-catenin with the destruction complex (Bos taurus)


name: Activation of NIK (Saccharomyces cerevisiae)


name: 2 H(+) + hexanoyl-CoA + 2 malonyl-CoA = 4-hydroxy-6-pentylpyran-2-one + 2 CO2 + 3 CoA


name: an N(2)-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA => a 2'-deoxyguanosine in DNA + glyoxal


name: MAPK4,6 translocate to nucleus (Sus scrofa)


name: ESTG binds ESR2:chaperone complex (Xenopus tropicalis)


name: Reduction of disulphide bonds in MHC II antigens (Rattus norvegicus)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Canis familiaris)


name: acetyl-CoA + 5 H(+) + holo-[ACP] + 5 malonyl-CoA => 3,5,7,9,11-pentaoxododecanoyl-[ACP] + 5 CO2 + 6 CoA


name: AMP(out) + CMP-N-acetyl-beta-neuraminate(in) => AMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: CYP19A1 hydroxylates TEST to EST17b (Bos taurus)


name: (2E)-geranyl diphosphate <=> (2S,4R)-bornyl diphosphate


name: 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: a fatty acyl-CoA + sphinga-(4E,8E)-dienine = an N-acyl-sphinga-4,8-dienine + CoA + H(+)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Caenorhabditis elegans)


name: acetyl-CoA + N(6)-methyl-L-lysyl-[histone] <=> CoA + H(+) + N(6)-acetyl-N(6)-methyl-L-lysyl-[histone]


name: NPAS4 binds ARNT2 (Drosophila melanogaster)


name: Parenchymal atROL translocates to HSCs (Mus musculus)


name: PBX1 gene expression is stimulated by NOTCH3 (Homo sapiens)


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Homo sapiens)


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Gallus gallus)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-methylpropanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] <=> CoA + N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein]


name: SENP1,2,5 proteolytically process SUMO3 (Canis familiaris)


name: Recruitment of PLCgamma to membrane (Gallus gallus)


name: H(+) + salicylate 2-O-beta-D-glucoside + UDP => salicylate + UDP-alpha-D-glucose


name: PP2A demethylation by PPME1 (Danio rerio)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Homo sapiens)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Canis familiaris)


name: SOX10 dimer binds the POU3F1 promoter (Homo sapiens)


name: 3-methyl-2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] => 2-methylpropanoyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: UCKL1 phosphorylates urindine, cytidine (Homo sapiens)


name: VRK1/VRK2 phosphorylate BANF1 (Sus scrofa)


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Gallus gallus)


name: DELE1(143-515) binds EIF2AK1 (HRI) (Homo sapiens)


name: AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it (Homo sapiens)


name: an S-alkyl-L-cysteine + H2O => an alkyl thiol + NH4(+) + pyruvate


name: 2 H2O + phenylpropanonitrile <=> 3-phenylpropanoate + NH4(+)


name: 3'-dephospho-CoA(in) + ADP(out) => 3'-dephospho-CoA(out) + ADP(in)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)


name: 2-oxoglutarate + O2 + oripavine = CO2 + formaldehyde + neomorphinone + succinate


name: Abortive initiation after formation of the first phosphodiester bond (Gallus gallus)


name: ATP + H2O + L-phenylalanine = AMP + D-phenylalanine + diphosphate + H(+)


name: DCAKD phosphorylates DP-CoA (Mus musculus)


name: The retrograde IFT train dissociates (Rattus norvegicus)


name: cyclomaltodextrin + H2O => linear maltodextrin


name: CDK4 phosphorylates RUNX2 (Canis familiaris)


name: 3-oxooctadecanoyl-CoA + H(+) + NADH => 3-hydroxyoctadecanoyl-CoA + NAD(+)


name: ADP + Fe(III)-enterobactin(in) + H(+) + phosphate => ATP + Fe(III)-enterobactin(out) + H2O


name: DAG and Ca+2 bind to PKC and tether it to membrane (Drosophila melanogaster)


name: Substrate:LAMP2a:HSP90 polymerizes (Homo sapiens)


name: 2 H(+) + m-xylene + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3-methylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Xenopus tropicalis)


name: guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: (E)-coniferaldehyde + AH2 => (E)-coniferol + A


name: Casein kinase II phosphorylates PTEN (Saccharomyces cerevisiae)


name: GDP + NAD(+) => H(+) + N(2)-(ADP-D-ribosyl)-GDP + nicotinamide


name: CoA + decanoate phytyl ester => decanoyl-CoA + phytol


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Caenorhabditis elegans)


name: Hemoglobin A is protonated and carbamated causing release of oxygen (Sus scrofa)


name: tBID binds to inactive BAX protein (Homo sapiens)


name: FLT mutants bind type I TKIs (Homo sapiens)


name: (R)-carnitine(in) + glycine betaine(out) <=> (R)-carnitine(out) + glycine betaine(in)


name: PSGs bind proteoglycans and TGF-beta1 (Canis familiaris)


name: 4-phospho-L-aspartate + H(+) + NADPH => L-aspartate 4-semialdehyde + NADP(+) + phosphate


name: JAK1-mediated phosphorylation of RAF1 (Gallus gallus)


name: G mRNA is translated into membrane-bound G protein (Homo sapiens)


name: GPI dimer isomerizes Fru(6)P to G6P (Bos taurus)


name: (Z)-(indol-3-yl)-N-(sulfonatooxy)methanimidothioate => (indol-3-yl)acetonitrile + sulfate + sulfur


name: 5-phosphooxy-L-glutamyl-tRNA(Gln) + NH4(+) => H(+) + L-glutaminyl-tRNA(Gln) + phosphate


name: Nucleoprotein translocates to the nucleolus (Homo sapiens)


name: RHOA:GTP binds ROCK, activating it (Drosophila melanogaster)


name: (S)-1-phenylethanol + NAD(+) = acetophenone + H(+) + NADH


name: Phosphorylation of ZAP-70 by Lck (Mus musculus)


name: The UDP/CysLT (P2Y17) receptor can bind UTP (Canis familiaris)


name: 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Rattus norvegicus)


name: L-glutamine(in) + L-threonine(out) + Na(+)(in) => L-glutamine(out) + L-threonine(in) + Na(+)(out)


name: 3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-methionine => H(+) + pterostilbene + S-adenosyl-L-homocysteine


name: 1H-pyrrole + CO2 => H(+) + pyrrole-2-carboxylate


name: L-arginine(in) + L-cysteine(out) + Na(+)(out) => L-arginine(out) + L-cysteine(in) + Na(+)(in)


name: chloride(out) + L-threonine(out) + 2 Na(+)(out) => chloride(in) + L-threonine(in) + 2 Na(+)(in)


name: SLC44A1 transports Cho from cytosol to mitochondrial matrix (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Canis familiaris)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Bos taurus)


name: alpha-D-glucose 1-phosphate + alpha-maltopentaose => alpha-maltohexaose + phosphate


name: a (3R)-3-hydroxyacyl-CoA + NADP(+) => a 3-oxoacyl-CoA + H(+) + NADPH


name: Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Gallus gallus)


name: Hydrolysis of Ran:GTP to Ran:GDP (Homo sapiens)


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Bos taurus)


name: 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH => 2-dehydro-3-deoxy-L-fuconate + NAD(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: AMP + decanoyl-[ACP] + diphosphate => ATP + decanoate + holo-[ACP]


name: chromatin-nuclear membrane anchor activity


name: Phenol can form a sulfate conjugate (Bos taurus)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phosphocholine + cholesterol => (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 (Mus musculus)


name: 4-coumaroyl-CoA + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside => a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA


name: CD28 homodimer binds B7-1 homodimer (Sus scrofa)


name: PLK3 phosphorylates CDC25C (Dictyostelium discoideum)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Homo sapiens)


name: dehydroabietadienal + H2O + NADP(+) <=> dehydroabietate + 2 H(+) + NADPH


name: SULTs transfer (SO4)2- group to PREG (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate = (1R,4R,5S)-(-)-guaia-6,10(14)-diene + diphosphate


name: TMEM55B translocates to the nucleus (Canis familiaris)


name: A + H2O + quinolin-8-ol <=> 8-hydroxyquinolin-2(1H)-one + AH2


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an N-acylethanolamine + H(+) => H2O + N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: glutaryl-CoA + H2O => CoA + glutarate + H(+)


name: SUMOylation of TDG with SUMO2,3 (Bos taurus)


name: 5alpha-dihydrotestosterone sulfate + H(+) + NADPH => (3beta,5alpha,17beta)-3-hydroxy-androstan-17-yl sulfate + NADP(+)


name: L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose => L-glutamate + UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Saccharomyces cerevisiae)


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Sus scrofa)


name: acetyl-CoA + N-terminal L-methionyl-L-tyrosyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-tyrosyl-[protein]


name: D-fructuronate(in) + H(+)(in) <=> D-fructuronate(out) + H(+)(out)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Danio rerio)


name: DT:HBEGF:CD9 is transported from clathrin-coated vesicle to endosome (Homo sapiens)


name: SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Canis familiaris)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Drosophila melanogaster)


name: a flavonol 7-O-beta-D-glucoside + malonyl-CoA => a flavonol 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methyl-3-oxobutanoyl-CoA + H(+) + NADH


name: a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GD1b (d18:1(4E)) + H(+) + UDP


name: Na+/H+ exchanger transport (at cell membrane) (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate <=> beta-acoradiene + diphosphate


name: Formation of CDK4/6:CCND complexes (Canis familiaris)


name: 2-hydroxybenzoyl-CoA + AMP + H(+) => 2-hydroxybenzoyl-5'-AMP + CoA


name: IL21 receptor STAT phosphorylation (Canis familiaris)


name: NGF binding to p75NTR inactivates RHOA (Gallus gallus)


name: n a quinone + n H(+) + n hydrogen sulfide <=> n a quinol + n sulfur


name: Recruitment of SYK to p-DAP12 (Gallus gallus)


name: MRN bound to shortened telomeres activates ATM (Dictyostelium discoideum)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Mus musculus)


name: cytidine(48) in tRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(48) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: a 1-(1-hydroxyalkyl)-sn-glycerol => an aldehyde + glycerol


name: Autophosphorylation of PAK1 (Bos taurus)


name: SYS1 binds AcM-ARFRP1 (Canis familiaris)


name: FMN-N(5)-oxide + H(+) + NADH => FMN + H2O + NAD(+)


name: Formation of allysine by LOX (Rattus norvegicus)


name: a 1,2-diacylglycerol + a glycerophospholipid => a 1-acyl-sn-glycero-3-phospholipid + a triacylglycerol


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Gallus gallus)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)


name: PP2A dephosphorylates inactive RAFs (Mus musculus)


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Schizosaccharomyces pombe)


name: n fibrin monomers -> fibrin multimer (Sus scrofa)


name: (2Z,6Z)-farnesyl diphosphate + diphosphate => isopentenyl diphosphate + neryl diphosphate


name: a 5'-end ribonucleotide-tRNA(His) + ATP + H(+) <=> a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate


name: cAMP hydrolysis by Cam-PDE 1 (Rattus norvegicus)


name: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O


name: Defective HLCS does not biotinylate 6x(PCCA:PCCB) (Homo sapiens)


name: a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP(+) = an (R)-2-alkyl-3-oxoalkanoate + H(+) + NADPH


name: (R)-pantolactone + A = 2-dehydropantolactone + AH2


name: FAR2 reduces PalmCoA to HXOL (Rattus norvegicus)


name: 1-O-alkyl-sn-glycero-3-phosphate + ADP + H(+) => 1-O-alkyl-sn-glycerol + ATP


name: H2O + monoacyl-sn-glycero-3-phosphate => a monoacylglycerol + phosphate


name: 2-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate => 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O


name: D-glyceraldehyde 3-phosphate + H2O + NAD(+) => (2R)-3-phosphoglycerate + 2 H(+) + NADH


name: (2E,6E)-farnesol + NADP(+) = (2E,6E)-farnesal + H(+) + NADPH


name: (S)-ureidoglycolate + 2 H(+) + H2O = CO2 + glyoxylate + 2 NH4(+)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Mus musculus)


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Sus scrofa)


name: (3S)-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA


name: (R)-lactate + ubiquinone-8 = pyruvate + ubiquinol-8


name: MMP14:TIMP2 binds proMMP2 (Mus musculus)


name: 3-deoxy-D-glycero-2,5-hexodiulosonate + H(+) + NADH => 2-dehydro-3-deoxy-D-gluconate + NAD(+)


name: TRPV1 binds TRPV1 blockers (Canis familiaris)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2 = 2-dehydro-D-glucose + H2O2 + L-glutamate


name: TNF-α:TNFR1 binds DENN/MADD (Rattus norvegicus)


name: SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to HNRNPA1 (Homo sapiens)


name: (3R)-hydroxyacyl-CoA dehydrogenase (NAD+) activity


name: pS181-S-Farn-Me KRAS4B binds BCL2L1 (Rattus norvegicus)


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)


name: EXA4 is converted to EXC4 by LTC4S (Homo sapiens)


name: TXNIP binds reduced thioredoxin (Bos taurus)


name: cucurbitacin B + H(+) + NADH => 23,24-dihydrocucurbitacin B + NAD(+)


name: 1,2-dehydroreticulinium reductase (NADPH) activity


name: (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+) => (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADPH + O2


name: brevianamide F + dimethylallyl diphosphate => deoxybrevianamide E + diphosphate


name: 6 localizes to the nuclear envelope (Homo sapiens)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Homo sapiens)


name: 3-oxooctadecanoyl-CoA + H(+) + NADPH => (3R)-hydroxyoctadecanoyl-CoA + NADP(+)


name: ADP + ADP <=> AMP + ATP [AK2] (Danio rerio)


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Saccharomyces cerevisiae)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Canis familiaris)


name: an alkylmercury + H(+) <=> an alkane + Hg(2+)


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-isoafricanol + diphosphate


name: a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone + H(+) + UDP => a 3'-hydro-2'-hydroxy-beta-oxodihydrochalcone + UDP-alpha-D-glucose


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Rattus norvegicus)


name: UMPS dimer decarboxylates OMP to UMP (Homo sapiens)


name: mature RAS proteins translocate to plasma membrane (Drosophila melanogaster)


name: dauca-4,7-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Gallus gallus)


name: a 14alpha-methyl steroid + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] = a Delta(14) steroid + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: diphosphate + valerena-4,7(11)-diene => (2E,6E)-farnesyl diphosphate


name: CLPXP degrades mitochondrial matrix proteins (Bos taurus)


name: NADPH + O2 + rifampicin <=> H(+) + H2O + NADP(+) + rifampicin para-naphthoquinone carboxamide


name: H2O + N-(9Z-octadecenoyl)-ethanolamine phosphate = N-(9Z-octadecenoyl) ethanolamine + phosphate


name: eNOS:NOSIP translocation from caveolae to intracellular compartments (Sus scrofa)


name: ALOX15 oxidises DHA to 17(S)-Hp-DHA (Canis familiaris)


name: 7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 2'-phosphate + H(+)


name: Binding of IRS to insulin receptor (Sus scrofa)


name: (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-glutamate => (6S)-5-formyl-5,6,7,8-tetrahydrofolate + L-glutamate


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Danio rerio)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Canis familiaris)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Mus musculus)


name: 2 D-glucopyranose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate


name: acetoacetate(out) + 2 Na(+)(out) = acetoacetate(in) + 2 Na(+)(in)


name: p38 MAPK activation by VEGFR (Drosophila melanogaster)


name: n H(+)(out) + taurocholate(out) <=> n H(+)(in) + taurocholate(in)


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Dictyostelium discoideum)


name: phloretin + UDP-alpha-D-glucose = H(+) + trilobatin + UDP


name: 15-methylhexadecasphing-4-enine 1-phosphate + ADP + H(+) => 15-methylhexadecasphing-4-enine + ATP


name: p-MII:SAG dissociates to p-RHO and SAG (Homo sapiens)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+) => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: CO2 + formaldehyde + neomorphinone + succinate => 2-oxoglutarate + O2 + oripavine


name: Cytoplasmic proteases cleave Profilaggrin producing Filaggrin (Homo sapiens)


name: sucrose + UDP-alpha-D-galactose <=> 6(F)-alpha-D-galactosylsucrose + H(+) + UDP


name: quercetin + UDP-beta-L-rhamnose = H(+) + quercitrin + UDP


name: CDKN1B is phosphorylated in response to estrogen (Canis familiaris)


name: 4-guanidinobutanamide + H2O = 4-guanidinobutanoate + NH4(+)


name: Expression of Lanosterol Demethylase (CYP51A1) (Homo sapiens)


name: p-4Y-SIRPA:CD47 binds SKAP2 (Rattus norvegicus)


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Gallus gallus)


name: Active ALK recruits PI3K (Rattus norvegicus)


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Rattus norvegicus)


name: TORC2 complex phosphorylates SGK1 (Homo sapiens)


name: Caspase-mediated cleavage of claspin (Mus musculus)


name: sucrose + H2O => glucose + fructose (Caenorhabditis elegans)


name: PDE4A hydrolyses cAMP to AMP (Bos taurus)


name: AMP + H2O => adenosine + orthophosphate [NT5C1B] (Xenopus tropicalis)


name: CYP2U1 19-hydroxylates ARA (Mus musculus)


name: FOXM1 binds CENPF promoter (Homo sapiens)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Mus musculus)


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Homo sapiens)


name: a medium chain fatty acid + ATP + CoA <=> a medium-chain fatty acyl-CoA + AMP + diphosphate


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Danio rerio)


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Canis familiaris)


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Rattus norvegicus)


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Mus musculus)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Bos taurus)


name: Activated JAK1 binds RAF1 (Rattus norvegicus)


name: A + all-trans-phytofluene <=> AH2 + all-trans-zeta-carotene


name: ergosterol + H(+) + L-aspartate => 1-(ergostan-3beta-yl)-L-aspartate + H2O


name: Association of cell cycle proteins with the APC/C:Cdh1 complex (Bos taurus)


name: (2E)-butenoyl-[ACP] + H(+) + NADH => butanoyl-[ACP] + NAD(+)


name: Activation of EPACs by cAMP (Gallus gallus)


name: Phosphorylation of Platelet Sec-1 (Caenorhabditis elegans)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-3-phosphoethanolamine + a cardiolipin


name: E2F6:TFDP1 binds to MGA:MAX (Bos taurus)


name: NTPDase1 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: ATPase-coupled urea transmembrane transporter activity


name: ATP + H2O + urea(out) = ADP + H(+) + phosphate + urea(in)


name: S-adenosyl-L-methionine + tricetin = 3'-O-methyltricetin + H(+) + S-adenosyl-L-homocysteine


name: all-trans-antheraxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => all-trans-violaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Clathrin internalises EPH:EFN complexes (Homo sapiens)


name: MMACHC:cob(II)alamin binds MMADHC (Homo sapiens)


name: RHOD GAPs stimulate RHOD GTPase activity (Saccharomyces cerevisiae)


name: Cho transports from the extracellular space to the cytosol (Canis familiaris)


name: HOXB1 gene is transcribed (Homo sapiens)


name: 1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol => an alkyl cinnamate + beta-D-glucose


name: 2-O-[(E)-sinapoyl]-D-glucarate + CoA => (E)-sinapoyl-CoA + D-glucarate


name: Phosphorylation of LIMK-1 by PAK (Homo sapiens)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Mus musculus)


name: H2O + L-threonyl-L-threonine <=> 2 L-threonine


name: a short-chain (3S)-3-hydroxyacyl-CoA = a short-chain (2E)-enoyl-CoA + H2O


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Homo sapiens)


name: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate


name: hapalindole H => 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole


name: 3-isopropylcatechol + H2O + NAD(+) => 2-isopropylphenol + H(+) + NADH + O2


name: ITPA hydrolyses XTP to XMP (Rattus norvegicus)


name: ATP + geranoyl-CoA + hydrogencarbonate <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + H(+) + phosphate


name: TFAP2A binds TFAP2B (Drosophila melanogaster)


name: IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Sus scrofa)


name: ASIC3 channel blockers bind ASIC3 trimer (Caenorhabditis elegans)


name: Alkalization of the phagosomal lumen by NOX2 (Gallus gallus)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Schizosaccharomyces pombe)


name: O2 + pregnenolone + reduced [NADPH--hemoprotein reductase] => 7alpha-hydroxypregnenolone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2S)-2-aminobutanoate + H2O + NAD(+) = 2-oxobutanoate + H(+) + NADH + NH4(+)


name: "enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)"


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Mus musculus)


name: 2 glutathione + thiosulfate => glutathione disulfide + 2 H(+) + hydrogen sulfide + sulfite


name: SLC25A11 exchanges 2-OG and MAL (Homo sapiens)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Dictyostelium discoideum)


name: SLC19A2/3 transport extracellular THMN to cytosol (Dictyostelium discoideum)


name: Removal of remaining Flap from the C-strand (Mus musculus)


name: a medium-chain 3-oxoacyl-[ACP] + dihydroxyacetone phosphate <=> a 2-oxo-3-(phosphooxy)propyl medium-chain 3-oxoalkanoate + holo-[ACP]


name: MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Drosophila melanogaster)


name: petunidin + UDP-alpha-D-galactose = petunidin 3-O-beta-D-galactoside + UDP


name: HLCS biotinylates ACACA:Mn2+ (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acyl-sphingoid base => a 1,2-diacyl-sn-glycerol + an inositol-1-phosphoceramide


name: 2Fe-2S is inserted in UQCRFS1 (Canis familiaris)


name: 1-O-(1Z-hexadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+)


name: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 => (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + UDP-alpha-D-glucuronate => (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP


name: Myristoylation of tBID by NMT1 (Danio rerio)


name: NTPDase2 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Mus musculus)


name: CYP4F12 18-hydroxylates ARA (Rattus norvegicus)


name: RNF181 polyubiquinates BCL10 (Rattus norvegicus)


name: 3-dehydroteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => 3-dehydro-6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: ATP + choline(out) + H2O => ADP + choline(in) + H(+) + phosphate


name: H2O + L-phenylalanine + O2 <=> 3-phenylpyruvate + H2O2 + NH4(+)


name: fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate (Gallus gallus)


name: Beta-catenin recruits CDC73 and LEO1 (Caenorhabditis elegans)


name: apo-Transferrin dissociates from the receptor complex (Bos taurus)


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Mus musculus)


name: MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Sus scrofa)


name: ESR1 binds to TFF1 gene promoter (Bos taurus)


name: 9,10-epoxy-(12Z)-octadecenoate + H2O <=> 9,10-dihydroxy-(12Z)-octadecenoate


name: phosphate + sphinga-4E,14Z-dienine => H2O + sphinga-4E,14Z-dienine-1-phosphate


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Homo sapiens)


name: (S)-tetrahydropalmatine + H(+) + S-adenosyl-L-homocysteine => (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine


name: H(+) + S-adenosyl-L-homocysteine + toralactone => nor-toralactone + S-adenosyl-L-methionine


name: carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity


name: LRRC16A binds F-actin capping protein (Drosophila melanogaster)


name: p107 (RBL1) binds CyclinE/A:CDK2 (Dictyostelium discoideum)


name: AMP + beta-nicotinamide D-ribonucleotide + 2 H(+) => H2O + NAD(+)


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex  (Rattus norvegicus)


name: Caspase-mediated cleavage of Desmoglein 1 (Xenopus tropicalis)


name: poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity


name: hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Sus scrofa)


name: SIRT6 deacetylates RBBP8 (Gallus gallus)


name: GLB1 hydrolyses a glycosaminoglycan (Mus musculus)


name: 3-(methylsulfanyl)propanoate + ATP + CoA = 3-(methylsulfanyl)propanoyl-CoA + AMP + diphosphate


name: (E)-4-hydroxynon-2-enal + H2O + NAD(+) => (E)-4-hydroxynon-2-enoate + 2 H(+) + NADH


name: ABCA4 mediates atRAL transport (Drosophila melanogaster)


name: (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-dihydrotricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-hydroxy-5-methyl-1-naphthoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 2,7-dihydroxy-5-methyl-1-naphthoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 3'-phosphoadenylyl sulfate + an aliphatic (Z)-desulfo-glucosinolate => a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + adenosine 3',5'-bisphosphate + H(+)


name: (+)-7-isojasmonate + L-isoleucine => H2O + L-isoleucine-(+)-7-isojasmonate


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Danio rerio)


name: EML4 binds to microtubules (Xenopus tropicalis)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Sus scrofa)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Mus musculus)


name: dihydroferuloyl-CoA + NADP(+) <=> (E)-feruloyl-CoA + H(+) + NADPH


name: Activated FGFR4 binds FRS3 (Drosophila melanogaster)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA <=> 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Calcium binds calmodulin at the synapse (Homo sapiens)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Caenorhabditis elegans)


name: SCD desaturates ST-CoA to OLE-CoA (Saccharomyces cerevisiae)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Gallus gallus)


name: acetyl-CoA + H2O => acetate + CoASH (Xenopus tropicalis)


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol => (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone


name: (1R,5R)-sabinene + diphosphate => (2E)-geranyl diphosphate


name: Proteasomal cleavage of substrate (Homo sapiens)


name: Calcium Binds Caldesmon (Canis familiaris)


name: RBKS phosphorylates ribose to R5P (Schizosaccharomyces pombe)


name: G protein-coupled opioid receptor activity


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Sus scrofa)


name: H2O + octanoyl-CoA = adenosine 3',5'-bisphosphate + 2 H(+) + S-octanoyl-4'-phosphopantetheine


name: H2O + N,N-dimethylaniline N-oxide + NADP(+) => H(+) + N,N-dimethylaniline + NADPH + O2


name: Interleukin-16 is secreted (Rattus norvegicus)


name: TRPA1 tetramer binds TRPA1 antagonists (Rattus norvegicus)


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Rattus norvegicus)


name: COMT transfers Met to DA to form 3MT (Homo sapiens)


name: 2-oxoglutarate + O2 + penicillin N => CO2 + deacetoxycephalosporin C + H2O + succinate


name: Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol


name: (2R,3S,4S)-3,4-leucopelargonidin + NADP(+) = (2R,3R)-dihydrokaempferol + H(+) + NADPH


name: ATP + L-threonine = ADP + H(+) + O-phospho-L-threonine


name: ARMS is phosphorylated by active TrkA receptor (Mus musculus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + L-serine


name: eicosanoyl-CoA + FAD + H(+) = (2E)-eicosenoyl-CoA + FADH2


name: H2O + octanoyl-CoA <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-octanoyl-4'-phosphopantetheine


name: Ligation of newly synthesized repair patch to incised DNA in GG-NER (Homo sapiens)


name: a (2R)-2-hydroxycarboxylate + NAD(+) => a 2-oxocarboxylate + H(+) + NADH


name: AGK:Mg2+ phosphorylates MAG, DAG (Danio rerio)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Serum albumin binds 2-lysophosphatidylcholine (Mus musculus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Xenopus tropicalis)


name: PIAS2-2 SUMOylates THRA with SUMO1 (Bos taurus)


name: butanoyl-[ACP] + NADP(+) => (2E)-butenoyl-[ACP] + H(+) + NADPH


name: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O


name: beta-D-fructose 6-phosphate => D-arabino-hex-3-ulose 6-phosphate


name: beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-dodecanoylsphing-4-enine


name: (2S)-heptan-2-amine + H2O + NAD(+) => H(+) + heptan-2-one + NADH + NH4(+)


name: mannosyl-diinositol phosphorylceramide phospholipase activity


name: IL12B:IL23A translocates from ER lumen to extracellular space (Rattus norvegicus)


name: 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH => 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: Mitochondrial dALA translocates to cytosol (Homo sapiens)


name: PTK2 is recruited to methylated ESR1 (Homo sapiens)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: a 3-dehydro-D-guloside <=> a 3-dehydro-D-glucoside


name: dGTP + 2 H2O <=> dGMP + 2 H(+) + 2 phosphate


name: TDP(out) + UTP(in) => TDP(in) + UTP(out)


name: M protein gets N-glycosylated (Homo sapiens)


name: H2O + N-(acetyl)-sphing-4-enine <=> acetate + sphing-4-enine


name: 7,8-dihydromonapterin 3'-triphosphate => 7,8-dihydroneopterin 3'-triphosphate


name: 3-methylcatechol + CO2 + NADH => 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+)


name: Acyl Ghrelin and C-Ghrelin are secreted (Sus scrofa)


name: AGO1,2:small RNA complexes interact with chromatin (Schizosaccharomyces pombe)


name: 3'-phosphoadenylyl sulfate + beta-D-galactosyl-(1<->1)-sphing-4-enine <=> 6-O-sulfo-beta-D-galactosyl-(1<->1)-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Rattus norvegicus)


name: 1-guanidino-1-deoxy-scyllo-inositol + phosphate => 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O


name: Expression of Glycerol-3-phosphate Acyltransferase (GPAM, GPAT) (Homo sapiens)


name: CR2 binds C3d, C3dg, iC3b (Canis familiaris)


name: p-T,Y MAPKs dimerize (Xenopus tropicalis)


name: malonyl-CoA + pelargonidin 3-O-(6-O-[(E)-caffeoyl]-beta-D-glucoside) 5-O-beta-D-glucoside <=> 4'''-demalonylsalvianin + CoA


name: Epsin family proteins bind ubiquitinated cargo (Canis familiaris)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Rattus norvegicus)


name: Phosphorylation of L1 by SRC (Mus musculus)


name: (2Z,6Z)-farnesyl diphosphate => (Z)-gamma-bisabolene + diphosphate


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Canis familiaris)


name: P2Y11 receptor can bind to ATP (Canis familiaris)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: Activated phosphorylated TAK1 kinase phosphorylates and activates IRD5 (Drosophila melanogaster)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose <=> alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-Glc + GDP + H(+)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + H(+) + malonyl-CoA => (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO2 + CoA


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + heptadecanoyl-CoA + O2 <=> (9Z)-heptadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ME2 tetramer decarboxylates MAL to PYR (Bos taurus)


name: 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + UDP-alpha-D-glucuronate <=> 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronate] + H(+) + UDP


name: IMPAD1 hydrolyses PAP to AMP (Rattus norvegicus)


name: ATP + H(+)(in) + H2O => ADP + 2 H(+)(out) + phosphate


name: Phosphorylation of EGFR by SRC kinase (Drosophila melanogaster)


name: a bacteriochlorophyllide d + H2O + S-adenosyl-L-methionine => 5'-deoxyadenosine + a 7(1)-hydroxybacteriochlorophyllide d + H(+) + L-methionine


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Homo sapiens)


name: Factor D cleaves C3(H2O)-bound Factor B (Danio rerio)


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Canis familiaris)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Saccharomyces cerevisiae)


name: beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enine + cholesterol <=> cholesteryl 3-beta-D-glucoside + N-(15Z-tetracosenoyl)-sphing-4-enine


name: p-S446-IRF5 dimer translocates to the nucleus (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + talarodiene


name: OPTN binds TBK1 within the activated TLR4 complex (Canis familiaris)


name: (S)-4,5-dihydroxypentane-2,3-dione + ATP = (2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H(+)


name: a lactoside III(4)-a-Fuc-Lc4Cer + GDP + H(+) => GDP-beta-L-fucose + Lc4Cer


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Homo sapiens)


name: Methylthio-ribulose-P = Methylthio-ribose-P (Saccharomyces cerevisiae)


name: 2-deoxy-alpha-L-fucosylaclacinomycin S + dTDP + H(+) => aclacinomycin S + dTDP-2-deoxy-beta-L-fucose


name: N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1248) in human 18S rRNA + S-methyl-5'-thioadenosine


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Bos taurus)


name: FAAH hydrolyses AEA to AA and ETA (Rattus norvegicus)


name: Release of eIF4E from the inactive eIF4E:4E-BP complex  (Bos taurus)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Xenopus tropicalis)


name: GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Canis familiaris)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN2B (GRIN2B) (Homo sapiens)


name: CYP2F1 dehydrogenates 3-methylindole (Rattus norvegicus)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Canis familiaris)


name: ADP + H(+) + iron(III) dicitrate(in) + phosphate => ATP + H2O + iron(III) dicitrate(out)


name: (3Z)-phytochromobilin + 2 oxidized [2Fe-2S]-[ferredoxin] => biliverdin IXalpha + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: ADP-alpha-D-glucose + D-glucose 6-phosphate = ADP + alpha,alpha-trehalose 6-phosphate + H(+)


name: avenacoside B + H2O <=> 26-desgluco-avenacoside B + D-glucose


name: Integrin alphaXbeta2 binds JAM3 (Gallus gallus)


name: EXT1:EXT2 transfer GlcNAc to the heparan chain (Bos taurus)


name: PAK1 phosphorylates LIMK1 (Rattus norvegicus)


name: Nuclear TIM is degraded by the 26S proteasome (Drosophila melanogaster)


name: CTP(out) + dCDP(in) <=> CTP(in) + dCDP(out)


name: HAS1,2,3 mediate the polymerization of HA (Xenopus tropicalis)


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Mus musculus)


name: type 4 metabotropic glutamate receptor binding


name: Protein kinase C, alpha type phosphorylates MARCKS (Mus musculus)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Bos taurus)


name: KCNIP3 binds NPAS4 gene promoter (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate <=> 2-(9Z-octadecenoyl)-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: H2O + hypoxanthine + O2 = H2O2 + xanthine


name: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + NAD(+) <=> bacteriochlorophyllide a + H(+) + NADH


name: decanoyl-AMP + holo-[ACP] = AMP + decanoyl-[ACP] + H(+)


name: (6R)-10-formyltetrahydrofolate + H2O + NADP(+) => (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + octadecanoyl-CoA => 1,2-di-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + CoA


name: Fe3+ dissociates from holoTF:TFRC dimer (Bos taurus)


name: Defective GFPT1 does not transfer an amino group from L-Gln to F6P to form GlcN6P (Homo sapiens)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3' incision by ERCC5 (XPG) in TC-NER (Rattus norvegicus)


name: CDK1 phosphorylates NUP98 (Gallus gallus)


name: AMP + 2 H(+) + 2 phosphate => ATP + 2 H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: estrone + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => androst-4-ene-3,17-dione + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: alpha,alpha-trehalose + phosphate => beta-D-glucose 1-phosphate + D-glucose


name: Surface deployment of platelet dense granule membrane components (Xenopus tropicalis)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Mus musculus)


name: D-galactono-1,5-lactone + H2O = D-galactonate + H(+)


name: USP4 deubiquitinate TRAF2,TRAF6 (Homo sapiens)


name: 6-phospho-D-gluconate + NAD(+) => 6-phospho-2-dehydro-D-gluconate + H(+) + NADH


name: Transport (influx) of bile salts and acids by OATP-A (Homo sapiens)


name: USP21 deubiquitinates GATA3,IL33 (Homo sapiens)


name: NOTCH1 PEST domain mutants bind HES1 promoter (Homo sapiens)


name: an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + H2O => an L-N,N-dihydroxypolyhomomethionine + H(+)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + H(+) + UDP => (2R)-3-phosphoglycerate + UDP-alpha-D-glucose


name: Crk's SH3 domain engages C3G (Mus musculus)


name: H2A-H2B histone complex chaperone activity


name: RGGT binds the RAB-binding subunit (Caenorhabditis elegans)


name: NEIL3 cleaves thymine glycol from telomeric DNA (Homo sapiens)


name: [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] <=> [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]


name: a 2,3-saturated fatty acid + H2O2 => a 3-hydroxy fatty acid + H2O


name: Formation of HIF:CBP:p300 complex at promoters (Homo sapiens)


name: [L-4-(L-arginin-2-N-yl)aspartate](n) + ATP + L-aspartate <=> [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + H(+) + phosphate


name: KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Gallus gallus)


name: CEBPA binds the promoter of the CEBPE gene (Homo sapiens)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Caenorhabditis elegans)


name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Danio rerio)


name: CMP-N-acetyl-beta-neuraminate + ganglioside GM1 (d18:1(4E)/18:0) => CMP + ganglioside GD1a (18:1(4E)/18:0) + H(+)


name: E2F6 forms the PRC1L4 complex (Bos taurus)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: LARG activation by G alpha 12/13 (Bos taurus)


name: L-arginine + L-cysteinyl-[NO transferase protein] + NADPH + 2 O2 = 2 H2O + L-citrulline + NADP(+) + S-nitroso-L-cysteinyl-[NO transferase protein]


name: an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O => a guanosine in RNA + H(+) + lactate


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Caenorhabditis elegans)


name: THEM86B hydrolyses PMCHO, PMETAM (Xenopus tropicalis)


name: LIPC dimer binds heparin (Canis familiaris)


name: ULK1 is dephosphorylated (Dictyostelium discoideum)


name: 3'-phosphoadenylyl sulfate + UDP-N-acetyl-alpha-D-galactosamine 4-sulfate => adenosine 3',5'-bisphosphate + H(+) + UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate


name: ATP + L-lysine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine


name: Melanin-concentrating hormone receptors bind MCH (Mus musculus)


name: Association of INK4 family proteins with CDK4/6 (Mus musculus)


name: RAC2 binds effectors at the ER membrane (Rattus norvegicus)


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)


name: (10S)-hydroxy-(12Z)-octadecenoate + NAD(+) => 10-oxo-(12Z)-octadecenoate + H(+) + NADH


name: WWTR1:SMAD stimulates transcription of SMAD7 (Homo sapiens)


name: arsenate(in) + H(+)(in) => arsenate(out) + H(+)(out)


name: ST6GALNAC5,6 transfer Neu5Ac to GM1b (Mus musculus)


name: CDP(in) + CTP(out) <=> CDP(out) + CTP(in)


name: (E)-feruloyl-CoA + H(+) + S-adenosyl-L-homocysteine => (E)-caffeoyl-CoA + S-adenosyl-L-methionine


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Drosophila melanogaster)


name: hexan-2-one + hydrogen cyanide = (2S)-2-hydroxy-2-methylhexanenitrile


name: "Transferring alkyl or aryl groups, other than methyl groups"


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Plasmodium falciparum)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AH2 + cremeomycin => 2-hydroxy-4-methoxybenzoate + A + N2


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Drosophila melanogaster)


name: MBTPS1 (S1P) cleaves CREB3 (Canis familiaris)


name: Formation of NR-MED1 Coactivator Complex (Homo sapiens)


name: D-sorbitol + NADP(+) <=> H(+) + L-xylo-3-hexulose + NADPH


name: 1-O-alkyl-sn-glycero-3-phosphocholine + an acyl-CoA <=> 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Canis familiaris)


name: SUMOylation of DDX17 with SUMO1 (Caenorhabditis elegans)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O <=> H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Caenorhabditis elegans)


name: RAB5 and GAPVD1 bind AP-2 (Mus musculus)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(20)-[histone H4] + O2 <=> CO2 + formaldehyde + L-lysyl(20)-[histone H4] + succinate


name: (9Z,12Z)-octadecadienoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol <=> 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Rattus norvegicus)


name: RHOD translocates to the mitochondrial outer membrane (Saccharomyces cerevisiae)


name: HGD dioxygenates homogentisate (Dictyostelium discoideum)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2 => 2-dehydro-D-glucose + H2O2 + L-tyrosine


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Sus scrofa)


name: SPTLC complexes transfer acyl-CoA onto serine (Danio rerio)


name: N(omega),N(omega)-dimethyl-L-arginine + pyruvate => 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine


name: chrysophanol + H2O => chrysophanol-9-anthrone + O2


name: PAK1,2,3 phosphorylates MAPK6,4 (Caenorhabditis elegans)


name: (S)-methylmalonyl-CoA + pyruvate => oxaloacetate + propanoyl-CoA


name: (E)-caffeate + ATP + H(+) + 2 malonyl-CoA = AMP + 2 CO2 + 2 CoA + diphosphate + hispidin


name: (20S)-protopanaxatriol + UDP-alpha-D-glucose <=> (20S)-ginsenoside Rh1 + H(+) + UDP


name: Netrin-4 binds DCC/UNC5A (Rattus norvegicus)


name: acetate + L-2,4-diaminobutanoate => (2S)-2-acetamido-4-aminobutanoate + H2O


name: (R)-pantoate + NAD(+) <=> (R)-4-dehydropantoate + H(+) + NADH


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Xenopus tropicalis)


name: ATP + H2O + Mn(2+)(in) => ADP + H(+) + Mn(2+)(out) + phosphate


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + O-phospho-L-seryl-[protein] => 1D-myo-inositol hexakisphosphate + O-diphospho-L-seryl-[protein]


name: TRAF6 binds MALT1 oligomers (Canis familiaris)


name: rDNA spacer replication fork barrier binding, bending


name: TRPA1 tetramer binds TRPA1 antagonists (Drosophila melanogaster)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: PTPN7 binds p-T,Y-MAPK (Dictyostelium discoideum)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Mus musculus)


name: RP2 activates the GTPase activity of ARL3 (Caenorhabditis elegans)


name: L-glutamine + scyllo-inosose <=> 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Mus musculus)


name: 3-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine => 3-hydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine


name: ATP binds G-protein beta associated TRiC/CCT (Caenorhabditis elegans)


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Mus musculus)


name: CARM1 methylates arginine-27 of histone H3 (H3R26) (Mus musculus)


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Dictyostelium discoideum)


name: 2-(3,5-dihydroxyphenyl)-2-oxoacetate + CoA + H(+) => (3,5-dihydroxyphenyl)acetyl-CoA + O2


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Homo sapiens)


name: AMP + H(+) + tetradecanoyl-[ACP] => holo-[ACP] + tetradecanoyl-AMP


name: 15-methylhexadecasphinganine + NADP(+) => 3-dehydro-15-methylhexadecasphinganine + H(+) + NADPH


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Saccharomyces cerevisiae)


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Homo sapiens)


name: PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Dictyostelium discoideum)


name: 3-(4-hydroxyphenyl)pyruvate + O2 = CO2 + homogentisate


name: 3-hydroxyhispidin + O2 <=> 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol => a triacylglycerol + an acyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Homo sapiens)


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Sus scrofa)


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Homo sapiens)


name: Cables link CDK5 and ABL1 (Homo sapiens)


name: AUF1 (hnRNP D0) is ubiquitinylated (Dictyostelium discoideum)


name: Inner coat assembly and cargo binding (Bos taurus)


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Drosophila melanogaster)


name: Trans-autophosphorylation of ERBB4 homodimers (Gallus gallus)


name: a 1-acyl-sn-glycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA


name: FOXO4 binds ATXN3 (Caenorhabditis elegans)


name: L-asparagine(in) + Na(+)(in) => L-asparagine(out) + Na(+)(out)


name: rifamycin SV hemiaminal => H(+) + rifamycin SV ortho-naphthoquinone carboxamide


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Homo sapiens)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Bos taurus)


name: Dephosphorylation of CK2-modified condensin I (Dictyostelium discoideum)


name: chloride(out) + L-threonine(out) + 2 Na(+)(out) <=> chloride(in) + L-threonine(in) + 2 Na(+)(in)


name: UDP-alpha-D-glucuronate + wogonin => UDP + wogonin 7-O-beta-D-glucuronate


name: CD22 binds itself to form homo-oligomers (Rattus norvegicus)


name: ZIP8 mediates zinc influx into cells (Sus scrofa)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Mus musculus)


name: mesaconate + succinyl-CoA => 2-methylfumaryl-CoA + succinate


name: ent-kaur-16-ene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> ent-kaur-16-en-19-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 3,17-didehydrostemmadenine + H2O + NADPH <=> (16R)-deshydroxymethyl-stemmadenine + formate + NADP(+)


name: 1-butanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Caenorhabditis elegans)


name: adenosine(4220) in 28S rRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(4220) in 28S rRNA + S-adenosyl-L-homocysteine


name: PGG2 is reduced to PGH2 by PTGS2 (Mus musculus)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Caenorhabditis elegans)


name: Internal Methylation of mRNA (Bos taurus)


name: NADPH transfers electrons to FDXR (Canis familiaris)


name: Recruitment of BCAR1 to PTK2 complex (Gallus gallus)


name: SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region (Homo sapiens)


name: REV1 inserts dCMP opposite to AP sites in DNA (Rattus norvegicus)


name: CLPXP binds mitochondrial matrix proteins (Canis familiaris)


name: CYTH proteins bind ARF1:GTP (Canis familiaris)


name: 3-dehydrocarnitine + acetyl-CoA => 3-dehydrocarnityl-CoA + acetate


name: H2O + 2 oxidized [azurin] + tyramine = (4-hydroxyphenyl)acetaldehyde + 2 H(+) + NH4(+) + 2 reduced [azurin]


name: Activated protein C binds Protein S (Gallus gallus)


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Canis familiaris)


name: Clathrin internalises EPH:EFN complexes (Caenorhabditis elegans)


name: 3'-L-prolyl-AMP + holo-[peptidyl-carrier protein] = AMP + L-prolyl-[peptidyl-carrier protein]


name: SGSH hydrolyses Heparan sulfate chain(7) (Canis familiaris)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: 2,4-dichloroaniline reductive dehalogenase activity


name: G-proteins dissociate from plasma-membrane estrogen receptors (Gallus gallus)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Xenopus tropicalis)


name: 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol => 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+)


name: acetyl-CoA + AH2 + H(+) + 3 malonyl-CoA + 2 S-adenosyl-L-methionine <=> A + clavatol + 3 CO2 + 4 CoA + H2O + 2 S-adenosyl-L-homocysteine


name: a 3',5'-unsubstituted flavanone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => a 3',5'-dihydroxyflavanone + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Binding of RRN3 to RNA Polymerase I (Sus scrofa)


name: bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE (Sus scrofa)


name: Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Danio rerio)


name: sulfosungeidine F <=> H(+) + sulfate + sungeidine A


name: ZIP6 and ZIP14 mediate zinc influx into cells (Canis familiaris)


name: Defective SI does not hydrolyze Mal (Homo sapiens)


name: 12alpha,13alpha-dihydroxyfumitremorgin C + dimethylallyl diphosphate = diphosphate + fumitremorgin B


name: Disassociation of CLIP from MHC II (Rattus norvegicus)


name: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Homo sapiens)


name: Activated FGFR1 phosphorylates SHC1 (Canis familiaris)


name: Noradrenaline clearance from the synaptic cleft (Xenopus tropicalis)


name: Autocatalytic phosphorylation of FGFR4 (Gallus gallus)


name: carboxyspermidine + H2O + NADP(+) <=> H(+) + L-aspartate 4-semialdehyde + NADPH + putrescine


name: Activation of RAC1 by VAV (Canis familiaris)


name: HSF1 trimer translocates to the nucleus (Dictyostelium discoideum)


name: geranylgeranyl diphosphate + H2O = cyclooctat-9-en-7-ol + diphosphate


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Bos taurus)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Canis familiaris)


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Xenopus tropicalis)


name: 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 4-acetamidobutanal + H2O + NAD(+) <=> 4-acetamidobutanoate + 2 H(+) + NADH


name: L-dopa + S-adenosyl-L-methionine <=> 3-O-methyl-L-dopa + H(+) + S-adenosyl-L-homocysteine


name: IGFBP1 binds IGF forming IGF:IGFBP1 (Danio rerio)


name: KDM5A-D demethylate Me2K5-histone H3 (Rattus norvegicus)


name: (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + 2 H(+) + 2 tricarballylate => fumonisin B1 + 2 H2O


name: AMP + diphosphate + glycyl-tRNA(Gly) => ATP + glycine + tRNA(Gly)


name: PLK1 phosphorylates FIRMM at S744 (Mus musculus)


name: Tyrosine is hydroxylated to dopa (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)


name: a carboxylate + H(+) + H2O2 => an aldehyde + H2O + O2


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + rhazimal


name: ethylenediaminetriacetate + FMN + glyoxylate + 2 H(+) + H2O => EDTA + FMNH2 + O2


name: calcium-dependent cysteine-type endopeptidase activity


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + ATP <=> 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + ADP + H(+)


name: Caspase 3-mediated cleavage of DFF45 (117) (Rattus norvegicus)


name: D-xylulose 5-phosphate + phosphate => acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Canis familiaris)


name: SIRT1 deacetylates HINT1 dimer (Drosophila melanogaster)


name: aculene B + holo-[peptidyl-carrier protein] => aculene D + L-prolyl-[peptidyl-carrier protein]


name: [deoxyhypusine synthase]-L-lysine + dehydrospermidine = [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine


name: 6-methylsalicylic acid synthase activity


name: Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine => 3,8-divinyl protochlorophyllide a + 5'-deoxyadenosine + 2 H(+) + L-methionine


name: (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O = (13R)-S-cysteinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glycine


name: MCM4, MCM6 and MCM7 form a heterotrimer (Homo sapiens)


name: H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + succinate


name: NAD(+) = cyclic ADP-beta-D-ribose + H(+) + nicotinamide


name: 3a localizes to the cell membrane (Homo sapiens)


name: (2S)-2-isopropylmalate(in) + sulfate(out) = (2S)-2-isopropylmalate(out) + sulfate(in)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Homo sapiens)


name: FAAH hydrolyses AEA to AA and ETA (Sus scrofa)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Gallus gallus)


name: AH2 + cob(III)alamin <=> A + cob(I)alamin + 2 H(+)


name: 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol + tRNA(Ala) => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-alanyl-tRNA(Ala)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O <=> (9Z)-octadecenoate + 1,3-dihexadecanoylglycerol + H(+)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Sus scrofa)


name: holo-[peptidyl-carrier protein] + L-threonyl-5'-AMP = AMP + L-threonyl-[peptidyl-carrier protein]


name: H2O + N-(4-aminobutyl)-3-aminopropanal + NAD(+) <=> 2 H(+) + N-(2-carboxyethyl)putrescine + NADH


name: DEGS2 oxygenates dihydroceramide (Bos taurus)


name: a 4-hydroxy-3-all-trans-polyprenylbenzoate + H(+) = a 2-all-trans-polyprenylphenol + CO2


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Homo sapiens)


name: uridine(13) in tRNA => pseudouridine(13) in tRNA


name: Binding of TFIIIC to Type 2 promoter (Drosophila melanogaster)


name: an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: "meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I"


name: C-terminal L-alpha-aminoacyl-[tubulin] + L-glutamate => C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + H2O


name: FMN + formaldehyde + 2 H(+) + H2O + sulfite => FMNH2 + methanesulfonate + O2


name: IRAK1 induces oligomerisation of TRAF6 (Canis familiaris)


name: proatranorin I + S-adenosyl-L-homocysteine => 4-O-demethylbarbatate + S-adenosyl-L-methionine


name: H(+) + NAD(+) + reduced 2[4Fe-4S]-[ferredoxin] = NADH + oxidized 2[4Fe-4S]-[ferredoxin]


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-acyl-4-hydroxy-15-methylhexadecasphinganine <=> a 1,2-diacyl-sn-glycerol + N-acyl-4-hydroxy-15-methylhexadecasphinganine-1-phosphocholine


name: HRH2 binds HRH2 antagonists (Homo sapiens)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Danio rerio)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Plasmodium falciparum)


name: 3-O-acetylpapaveroxine + H2O = acetate + H(+) + narcotine hemiacetal


name: NFE2L2 translocates from cytosol to nucleoplasm (Danio rerio)


name: 2-oxoglutarate + codeine + O2 <=> CO2 + formaldehyde + morphine + succinate


name: SIRT5 deacetylates Cytochrome C (Danio rerio)


name: GLB1 hydrolyses linker chain(2) (Drosophila melanogaster)


name: CREBBP acetylates HINT1 dimer (Mus musculus)


name: (S)-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] => (13S,14R)-1,13-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Exogenous soluble antigen targeted to more stable early endosome (Caenorhabditis elegans)


name: PTK6 phosphorylates KHDRBS1 (Rattus norvegicus)


name: Insulin receptor de-phosphorylation (Sus scrofa)


name: EGFR binds EPS15, EPN1, EPS15L1 (Drosophila melanogaster)


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Drosophila melanogaster)


name: acetyl-CoA + trans-glutaconate <=> (2E)-glutaconyl-CoA + acetate


name: 2-hydroxy-3-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine => 2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine


name: alpha-D-mannopyranose + beta-D-mannopyranosyl-(1->2)-D-mannopyranose => beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp + H2O


name: H2O + tetradecanoyl-CoA => adenosine 3',5'-bisphosphate + 2 H(+) + tetradecanoyl-4'-phosphopantetheine


name: 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2


name: guanidinoacetate + H2O <=> glycine + urea


name: F2R:ARRB1 binds MAPKs, SRC-1 (Mus musculus)


name: H2O + L-4-hydroxyglutamate semialdehyde + NAD(+) => (4S)-4-hydroxy-L-glutamate + 2 H(+) + NADH


name: a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol


name: a 2-hydroxy carboxylate + glutathione + H(+) => an S-(2-hydroxyacyl)glutathione + H2O


name: ethanolamine(out) + n H(+)(in) = ethanolamine(in) + n H(+)(out)


name: Keratin type I binds keratin type II (Xenopus tropicalis)


name: L-aspartate(in) + L-glutamate(out) => L-aspartate(out) + L-glutamate(in)


name: a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GD1c (d18:1(4E)) + CMP + H(+)


name: Transport of antigen loaded MHC II molecules to surface (Mus musculus)


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Xenopus tropicalis)


name: Dissociation of RAS:RAF complex (Canis familiaris)


name: (R)-dihydrolipoate + ATP + L-lysyl-[lipoyl-carrier protein] = AMP + diphosphate + H(+) + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein]


name: (2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-[protein] => 2'-deoxyribonucleotide-DNA + H(+) + S-methyl-L-cysteinyl-[protein]


name: (1R,3R)-chrysanthemal + H2O + NAD(+) = (1R,3R)-chrysanthemate + 2 H(+) + NADH


name: XDH oxidizes xanthine to form urate (Xenopus tropicalis)


name: Hydrolysis of internal thioester in C4b (Homo sapiens)


name: phosphate + solabiose = alpha-D-glucose 1-phosphate + D-galactose


name: an N-acyl-D-glucosamine <=> an N-acyl-D-mannosamine


name: ecgonine methyl ester + NADP(+) => ecgonone methyl ester + H(+) + NADPH


name: 2-oxoglutarate + 6-acetamido-3-aminohexanoate => 6-acetamido-3-oxohexanoate + L-glutamate


name: L-rhamnofuranose + NAD(+) = H(+) + L-rhamnono-1,4-lactone + NADH


name: Vitronectin (VTN) binds to C5b:C6:C7 (Canis familiaris)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Bos taurus)


name: chorismate + L-glutamine => (2S)-2-amino-4-deoxychorismate + L-glutamate


name: RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)


name: a 5'-end triphospho-(purine-ribonucleoside) in mRNA + GDP + H(+) => a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + diphosphate


name: Phosphorylation of COP1 at Ser-387  by ATM (Mus musculus)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Canis familiaris)


name: FN1 binds Collagen types I-V, VII (Canis familiaris)


name: a dicarboxylate(in) + L-erythro-7,8-dihydrobiopterin(out) => a dicarboxylate(out) + L-erythro-7,8-dihydrobiopterin(in)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Dictyostelium discoideum)


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Saccharomyces cerevisiae)


name: 2 2-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: D-threitol + NAD(+) <=> D-erythrulose + H(+) + NADH


name: 1H-imidazole + acetyl-CoA = CoA + N-acetylimidazole


name: 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH = isocholate + NADP(+)


name: mycothione is reduced to mycothiol (Mycobacterium tuberculosis)


name: 2 ATP + 2 H2O + protochlorophyllide a + reduced 2[4Fe-4S]-[ferredoxin] => 2 ADP + chlorophyllide a + oxidized 2[4Fe-4S]-[ferredoxin] + 2 phosphate


name: 3beta-hydroxy-chol-5-ene-24-oyl-CoA + A <=> 3beta-hydroxy-chol-5,22-dien-24-oyl-CoA + AH2


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Xenopus tropicalis)


name: Necl-1:Nectin-1 trans heterodimer interaction (Homo sapiens)


name: 8-carboxy-8-demethylriboflavin 5'-phosphate + 2 A + H2O + L-glutamate <=> 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 2 AH2 + CO2


name: H(+)(out) + novobiocin(in) => H(+)(in) + novobiocin(out)


name: CoA + O-tetradecanoyl-(R)-carnitine => (R)-carnitine + tetradecanoyl-CoA


name: (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+) => H2O + O2 + tyramine


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Rattus norvegicus)


name: Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Bos taurus)


name: (2E)-hexenoyl-[ACP] + H2O => (3R)-hydroxyhexanoyl-[ACP]


name: THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Danio rerio)


name: [translation elongation factor 2]-phosphate + ADP + H(+) => [translation elongation factor 2] + ATP


name: glycyl-L-proline + H2O => glycine + L-proline


name: Translocation of ERBB4s80 to the nucleus (Homo sapiens)


name: (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-2,6-dimethyloct-6-enoyl-CoA + NAD(+) <=> (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + H(+) + NADH


name: 2,3-didecanoyl-sn-glycerol + decanoate + H(+) => H2O + tridecanoylglycerol


name: 3-oxoisoapionate + H(+) => CO2 + L-erythrulose


name: 4-methylpentanoyl-CoA + H2O => 4-methylpentanoate + CoA + H(+)


name: SUMOylation of ING2 with SUMO1 (Xenopus tropicalis)


name: (+)-amorpha-4,11-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-GDP => GDP + H(+) + lactate


name: GGT dimers hydrolyse GSH (Drosophila melanogaster)


name: (2E)-octenoyl-[ACP] + H(+) + NADH <=> NAD(+) + octanoyl-[ACP]


name: STING recruits TBK1 and STAT6 (Xenopus tropicalis)


name: Activated PTK6 binds STAP2 (Danio rerio)


name: Telomere shortening during replicative exhaustion (Mus musculus)


name: L-iditol + NAD(+) => H(+) + keto-L-sorbose + NADH


name: a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+) => a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose


name: (24S)-25-epoxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (24S,25)-epoxy-7alpha-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Homo sapiens)


name: Addition of galactose to Core 6 glycoprotein (Gallus gallus)


name: Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Homo sapiens)


name: PPM1D dephosphorylates RUNX2 (Caenorhabditis elegans)


name: Formation of the GCN5-ATAC complex (Canis familiaris)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Canis familiaris)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Drosophila melanogaster)


name: FYN autophosphorylates (Rattus norvegicus)


name: Abortive termination of early transcription elongation by DSIF:NELF (Sus scrofa)


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Homo sapiens)


name: [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + H2O = 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + [mycofactocin precursor peptide]-C-terminal glycine


name: "[mycofactocin precursor peptide] peptidase"


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoate + O2 => (R)-2-hydroxyhexadecanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: a ganglioside Ac-O-9-GD3(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside Ac-O-9-GD2(d18:1(4E)) + H(+) + UDP


name: 2-phenylacetamide + H2O => 2-phenylacetate + NH4(+)


name: CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Caenorhabditis elegans)


name: ADP-L-glycero-beta-D-manno-heptose + L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) => ADP + H(+) + L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] <=> atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Mus musculus)


name: Separation of elongating transcript from template (Sus scrofa)


name: FOXO1,FOXO3 bind PINK1 gene promoter (Homo sapiens)


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine


name: (10aS)-10,10a-dihydrophenazine-1-carboxylate => 5,10-dihydrophenazine 1-carboxylate


name: N-decanoyl-(2S)-hydroxyglycine <=> decanamide + glyoxylate


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Drosophila melanogaster)


name: H2O + L-methionine <=> 2-oxobutanoate + methanethiol + NH4(+)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GA2 (d18:1(4E)) + H(+) + UDP


name: MPI isomerises Fru6P to Man6P (Drosophila melanogaster)


name: (3R)-hydroxybutanoate pentamer + [(3R)-hydroxybutanoate](n-5) + H(+) => [(3R)-hydroxybutanoate](n) + H2O


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Bos taurus)


name: 2-oxoglutarate + 3(1)-hydroxy-L-isoleucine + O2 => (4S)-3(1),4-dihydroxy-L-isoleucine + CO2 + succinate


name: PI is hydrolyzed to 2-acyl LPI by PLA2[13] (Rattus norvegicus)


name: 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + H(+) + UDP => (E)-coniferaldehyde + UDP-alpha-D-glucose


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Danio rerio)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Danio rerio)


name: uridine(54/55) in tRNA <=> pseudouridine(54/55) in tRNA


name: STARD7 binds PC (Drosophila melanogaster)


name: 3 H(+) + O2 + pheophorbide a + 2 reduced [2Fe-2S]-[ferredoxin] = epoxypheophorbide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a cis-3-alkyl-4-alkyloxetan-2-one <=> a cis-alkene + CO2


name: a 2'-deoxyribonucleoside + phosphate => a 2'-deoxyribonucleoside 3'-phosphate + H2O


name: VCAM1 binds Integrin alpha4beta1 (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + eicosanoyl-CoA <=> 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA


name: NADP(+) + reduced riboflavin <=> 2 H(+) + NADPH + riboflavin


name: SeMet is converted to AdoSeMet by MAT (Danio rerio)


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Dictyostelium discoideum)


name: Collagen type VII binds integrin alpha2beta1 (Mus musculus)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Xenopus tropicalis)


name: H(+) + ketocytochalasin + NADPH + O2 => H2O + iso-precytochalasin + NADP(+)


name: Arachidonic acid is oxidised to PGG2 by PTGS2 (Homo sapiens)


name: The 60S subunit joins the translation initiation complex  (Plasmodium falciparum)


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Sus scrofa)


name: L-cysteine + O-acetyl-L-homoserine = acetate + H(+) + L,L-cystathionine


name: (E,E,E)-alpha-springene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: rifampicin ortho-naphthoquinone carboxamide => rifampicin para-naphthoquinone carboxamide


name: PELI1 binds activated RIPK1:RIPK3 (Sus scrofa)


name: Phosphorylation of IFNGR1 by JAK kinases (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol <=> 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: nicotinate beta-D-ribonucleotide + phenol <=> H(+) + nicotinate + phenyl 5-phospho-alpha-D-ribofuranoside


name: neamine + UDP-alpha-D-glucose = 3''-deamino-3''-hydroxykanamycin B + H(+) + UDP


name: 3,4-dihydroxybenzoate + 2 H(+) + NADH => 3,4-dihydroxybenzaldehyde + H2O + NAD(+)


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Canis familiaris)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + GDP-alpha-D-mannose <=> a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP + H(+)


name: CYP26A1,B1,C1 4-hydroxylate atRA (Sus scrofa)


name: AH2 + O2 + octadecanoyl-CoA <=> (9Z)-octadecenoyl-CoA + A + 2 H2O


name: Formation of Cyclin A:Cdc2 complexes (Rattus norvegicus)


name: 3,6-dichlorocatechol + O2 = (2E,4E)-2,5-dichloromuconate + H(+)


name: (2E)-glutaconyl-CoA + H2O2 => glutaryl-CoA + O2


name: LMAN family proteins bind glycosylated cargo (Sus scrofa)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Gallus gallus)


name: dihydroxyacetone phosphate + hexadecanoyl-CoA => 1-hexadecanoylglycerone 3-phosphate + CoA


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Sus scrofa)


name: H(+) + hydroxylamine + L-asparagine = beta-L-aspartylhydroxamate + NH4(+)


name: AKT phosphorylates FOXO1A (Drosophila melanogaster)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Canis familiaris)


name: butanoyl-CoA + phosphate <=> butanoyl phosphate + CoA


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Saccharomyces cerevisiae)


name: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: DLD dimer dehydrogenates dihydrolipoyl (Caenorhabditis elegans)


name: NUBPL binds 4Fe-4S (Dictyostelium discoideum)


name: Interaction of DAP12 and CLM7 (Canis familiaris)


name: ATP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine => ADP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H(+) + phosphate


name: p-PKR dimer localizes to the nucleus (Bos taurus)


name: Receptor-mediated uptake of HA (Rattus norvegicus)


name: H2O2 + macarpine => dihydromacarpine + H(+) + O2