name: Exocytosis of secretory granule membrane proteins (Mus musculus)


name: a carboxylate + ATP + H(+) => an acyl-AMP + diphosphate


name: Formation of the CE:GMP intermediate complex (Drosophila melanogaster)


name: AVPR1A,2 bind AVPR antagonists (Canis familiaris)


name: UV-DDB ubiquitinates XPC (Canis familiaris)


name: formaldehyde + H2O2 + NH4(+) => H2O + methylamine + O2


name: Binding of Grb10 to the insulin receptor (Danio rerio)


name: gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Homo sapiens)


name: a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 = a (8S,9R)-5-glyceryl-2'-deoxycytidine in DNA + CO2 + glyoxylate


name: RANKL,sRANKL trimer binds RANK (Gallus gallus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: Abortive Initiation After Second Transition (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + L-serine <=> a 1,2-diacyl-sn-glycero-3-phospho-L-serine + ethanolamine


name: Tyrosine is monoiodinated (Homo sapiens)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + ATP + H2O => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + ADP + H(+) + phosphate


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A (E. coli) <=> a 1,2-diacyl-sn-glycerol + lipid A hexaacyl 1-(2-aminoethyl diphosphate)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Mus musculus)


name: MITF-M dimer and the SWI/SNF complex bind the TYRP1 gene (Homo sapiens)


name: 2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2'-hydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: L-alanine(in) + L-serine(out) = L-alanine(out) + L-serine(in)


name: EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Homo sapiens)


name: 1D-myo-inositol 4-phosphate + H2O = myo-inositol + phosphate


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Xenopus tropicalis)


name: H2O + L-lysine + NADP(+) <=> (S)-2-amino-6-oxohexanoate + H(+) + NADPH + NH4(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid IVA => a 2-acyl-sn-glycero-3-phosphocholine + a lipid IVB


name: ADH5 oxidises S-HMGSH to S-FGSH (Dictyostelium discoideum)


name: (2E,6E)-farnesal + H2O + NADP(+) => (2E,6E)-farnesoate + 2 H(+) + NADPH


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Sus scrofa)


name: Phosphorylation of IFNGR1 by JAK kinases (Bos taurus)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine => 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine


name: 2-oxooctadecanoate + H(+) + NADH => (S)-2-hydroxyoctadecanoate + NAD(+)


name: 5-phosphomethyl-dUMP in DNA + putrescine => 5-N(alpha)-putrescinyl-dTMP in DNA + phosphate


name: ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate <=> ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate


name: glycerol + NADP(+) = H(+) + L-glyceraldehyde + NADPH


name: Phosphorylation of USP8 by P-AKT (Dictyostelium discoideum)


name: 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol => 25-hydroxy-24-oxocalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+) => ATP + D-ribose 5-phosphate


name: 1,2-dihexanoylglycerol + hexadecanoyl-CoA <=> 1,2-dihexanoyl-3-hexadecanoylglycerol + CoA


name: H(+) + NADH + O2 + salicylate => 2,3-dihydroxybenzoate + H2O + NAD(+)


name: glycerol 2-phosphate + H2O => glycerol + phosphate


name: p-3Y-SHC1 dissociates from IGF1R (Mus musculus)


name: Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) (Homo sapiens)


name: CO-methylating acetyl-CoA synthase activity


name: ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O = a 5'-end phospho (purine-ribonucleoside) in mRNA + 2 H(+) + N(7)-methyl-GDP


name: 2,6-dihydroxypyridine + H(+) + NADH + O2 => 2,3,6-trihydroxypyridine + H2O + NAD(+)


name: Phosphorylation of MDM4 by CHEK2 (Mus musculus)


name: (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9Z,12Z)-octadecadienoyl-CoA + O2 + reduced [NADPH--hemoprotein reductase]


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Bos taurus)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII (Dictyostelium discoideum)


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Rattus norvegicus)


name: 3,3'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine => isorhamnetin + S-adenosyl-L-methionine


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Bos taurus)


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Homo sapiens)


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Bos taurus)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Canis familiaris)


name: Tankyrase binds AXIN (Rattus norvegicus)


name: C2CD3 binds the mother centriole (Sus scrofa)


name: L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-methionine => 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-homocysteine


name: (E)-but-1-en-1-SO-peroxol <=> (Z)-butanethial oxide


name: Crk's SH3 domain engages C3G (Homo sapiens)


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Caenorhabditis elegans)


name: H2O + kynuramine + O2 => 3-(2-aminophenyl)-3-oxopropanal + H2O2 + NH4(+)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Rattus norvegicus)


name: 2-chloroethanol + 2 Fe(III)-[cytochrome c] => chloroacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: 2-hydroxyhexacosanoyl-CoA + sphinganine <=> CoA + H(+) + N-(2-hydroxyhexacosanoyl)-sphinganine


name: HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)


name: IMPAD1 hydrolyses PAP to AMP (Homo sapiens)


name: cimicifugate K + CoA => (2R,3S)-piscidate + (E)-4-coumaroyl-CoA


name: ORC6 binds KPNA1 or KPNA6 (Canis familiaris)


name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-(9Z-octadecaenoyl)-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: L-Glutamate loading of synaptic vesicle (Mus musculus)


name: ERCC8 (CSA) binds stalled RNA Pol II (Dictyostelium discoideum)


name: Engulfment of particulate antigen into phagocytic vesicle (Sus scrofa)


name: RHOC activates endoplasmic reticulum effectors (Sus scrofa)


name: a ketone + H(+) + NADH => a secondary alcohol + NAD(+)


name: (E)-phenylacetaldehyde oxime = (Z)-phenylacetaldehyde oxime


name: DAG and Ca+2 bind to PKC and tether it to membrane (Sus scrofa)


name: STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Gallus gallus)


name: Partial autophosphorylation of PAK-2 at  Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 (Homo sapiens)


name: 1H-pyrrole + hydrogencarbonate => H2O + pyrrole-2-carboxylate


name: UCHL3, SENP8 cleave NEDD8 (Mus musculus)


name: Nectin-1:PVRL3 trans heterodimer formation (Drosophila melanogaster)


name: 2-acyl LPS is acylated to PS by LPSAT (Bos taurus)


name: Phosphorylated SMAD2/3 dissociates from TGFBR (Mus musculus)


name: (S)-malate + NAD(+) <=> CO2 + NADH + pyruvate


name: Ras:GTP binds p120-RasGAP (Drosophila melanogaster)


name: (S)-1-phenylethylamine + pyruvate => acetophenone + L-alanine


name: 3 H(+) + hexadecanoyl-CoA + 3 malonyl-CoA => 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: Vesicle budding (Caenorhabditis elegans)


name: LTA trimer binds TNFRSF1A,1B,14 (Danio rerio)


name: L-ascorbate(out) + N(pros)-phospho-L-histidyl-[protein] => L-ascorbate 6-phosphate(in) + L-histidyl-[protein]


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Dictyostelium discoideum)


name: sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity


name: 2-carboxy-5-(dihydroxymethyl)furan => 2-carboxy-5-formylfuran + H2O


name: acetylacetone + O2 = acetate + H(+) + methylglyoxal


name: RHOB binds effectors on endosomes (Rattus norvegicus)


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Danio rerio)


name: 2',4,4',6'-tetrahydroxychalcone + dimethylallyl diphosphate <=> desmethylxanthohumol + diphosphate


name: a ribonucleoside 5'-diphosphate + dCMP + H(+) => 2'-deoxycytidine + a ribonucleoside 5'-triphosphate


name: dalpatein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O = beta-D-apiofuranosyl-(1->6)-D-glucopyranose + dalpatein + H(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-GMP = glycolate + GMP + H(+)


name: H2O + O2 + spermidine = 4-aminobutanal + H2O2 + propane-1,3-diamine


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Mus musculus)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Mus musculus)


name: RNF41 ubiquitinates ERBB3 (Homo sapiens)


name: acetyl-CoA + L-2,4-diaminobutanoate <=> (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: NR3C2 binds NR3C2 antagonists (Plasmodium falciparum)


name: PTK6 phosphorylates ARHGAP35 (Rattus norvegicus)


name: Collagen type III degradation by MMP14 (Gallus gallus)


name: ATP + S-disulfanyl-L-cysteine + tRNA(Cys) <=> (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in)


name: acetate + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine => H2O + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine


name: (S)-nicotine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-nornicotine + formaldehyde + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N(6)-acetyl-L-lysyl-[alpha-tubulin] => acetate + L-lysyl-[alpha-tubulin]


name: griseophenone C + S-adenosyl-L-homocysteine => griseophenone D + S-adenosyl-L-methionine


name: Direct recruitment of PI3K to p-KIT (Homo sapiens)


name: 1D-myo-inositol 1,2,3,6-tetrakisphosphate + H2O => 1D-myo-inositol 1,2,3-trisphosphate + phosphate


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A => 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: Formation of active mTORC1 complex (Dictyostelium discoideum)


name: cis-4-hydroxy-L-proline + NAD(+) <=> 4-oxo-L-proline + H(+) + NADH


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Mus musculus)


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Gallus gallus)


name: SPRY2 translocates to the plasma membrane (Drosophila melanogaster)


name: 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin] => calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: DENND3 exchanges GTP for GDP on RAB12 (Rattus norvegicus)


name: 5-(2-hydroxyethyl)-4-methylthiazole + ATP => 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol = a 1,2-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Danio rerio)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: glycerol-3-phosphate dehydrogenase (NAD+) activity


name: GSTO dimers reduce DeHA to AscH- (Homo sapiens)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Bos taurus)


name: H2O + juglone = naphthalene-1,2,4,8-tetrol


name: Phosphorylated AMPK binds AMP (Bos taurus)


name: 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O => prephenate + S-adenosyl-L-methionine


name: SDK1 homophillic interaction (Sus scrofa)


name: JAK2 is phosphorylated, activated (Gallus gallus)


name: (9Z,12Z)-heptadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z)-heptadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: HLCS biotinylates ACACB (Drosophila melanogaster)


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Dictyostelium discoideum)


name: (-)-beta-barbatene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Efflux of 24-hydroxycholesterol (Homo sapiens)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Mus musculus)


name: p107 (RBL1) binds CyclinE/A:CDK2 (Caenorhabditis elegans)


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Canis familiaris)


name: aryl-aldehyde dehydrogenase (NADP+) activity


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Dictyostelium discoideum)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Schizosaccharomyces pombe)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Mus musculus)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Bos taurus)


name: TLE tetramers bind TCF/LEF at WNT promoters (Caenorhabditis elegans)


name: 2 ATP + H(+) <=> diphosphate + P(1),P(4)-bis(5'-adenosyl) tetraphosphate


name: a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH


name: 6-amino-2-oxohexanoate => Delta(1)-piperideine-2-carboxylate + H2O


name: Kinesin-5 is a homotetramer (Plasmodium falciparum)


name: FOXM1 binds CDC25A promoter (Homo sapiens)


name: H2O + NAD(+) = AMP + beta-nicotinamide D-ribonucleotide + 2 H(+)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: a dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine => a dolichyl N-acetyl-alpha-D-glucosaminyl phosphate + UDP


name: hexadecane-1,2-diol + 2 hexadecanoyl-CoA => 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA


name: ARL1:GTP binds SCOC (Caenorhabditis elegans)


name: (S)-malate + ubiquinone-8 <=> oxaloacetate + ubiquinol-8


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Dictyostelium discoideum)


name: p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Gallus gallus)


name: SALM1 binds NMDA receptor (Rattus norvegicus)


name: [amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O => [amino-group carrier protein]-C-terminal-L-glutamate + L-lysine


name: 2 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 O2 <=> 2 CO2 + 2 formaldehyde + L-arginyl-[protein] + 2 succinate


name: ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Danio rerio)


name: Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)


name: Addition of nucleotides between position +11 and +30 (Gallus gallus)


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Canis familiaris)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Drosophila melanogaster)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Homo sapiens)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Saccharomyces cerevisiae)


name: AH2 + asnovolin J + O2 <=> A + asnovolin A + H2O


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: androsterone + H(+) + NADH => 5alpha-androstane-3alpha,17beta-diol + NAD(+)


name: SEC31:SEC13 and v-SNARE recruitment (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base = a 1,2-diacyl-sn-glycerol + an alpha-D-mannosyl-6-(1D-myo-inositol phospho)-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base


name: SUMOylation of HIPK2 with SUMO1 (Schizosaccharomyces pombe)


name: Glutamine transport from astrocytes (Drosophila melanogaster)


name: L-isoleucine(out) + L-phenylalanine(in) => L-isoleucine(in) + L-phenylalanine(out)


name: [(1->4)-beta-D-mannuronosyl](n) + GDP-alpha-D-mannuronate => [(1->4)-beta-D-mannuronosyl](n+1) + GDP + H(+)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine


name: (25S)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => (25S)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 1-O-(1Z-hexadecenyl)-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH <=> 1-O-(1Z-hexadecenyl)-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) (Mus musculus)


name: T1R2/T1R3 dimer is a sweet taste receptor (Danio rerio)


name: cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine => 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: Arresten binds integrin alpha1beta1 (Xenopus tropicalis)


name: ASAP1 stimulates GTPase activity of ARF4 (Homo sapiens)


name: 10-deacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Rattus norvegicus)


name: Formation of Cyclin A:Cdk2 complexes (Caenorhabditis elegans)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Sus scrofa)


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + 2 succinate


name: a (3R)-3-hydroxyacyl-CoA = a (3S)-3-hydroxyacyl-CoA


name: ATF7IP binds SETDB1 (Drosophila melanogaster)


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Gallus gallus)


name: AFG3L2 binds mitochondrial matrix proteins (Saccharomyces cerevisiae)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Gallus gallus)


name: PTPN18 binds ERBB2:EGFR heterodimers (Homo sapiens)


name: USP49 deubiquitinates H2B (Canis familiaris)


name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA (Danio rerio)


name: Resumption of elongation after recovery from pausing (Xenopus tropicalis)


name: SALMs 1-4 bind reticulon 3 (Drosophila melanogaster)


name: Recruitment of SYK to p-FCERI gamma subunit (Rattus norvegicus)


name: 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + H2O + O2 <=> a 2'-deoxycytidine in single-stranded DNA + CO2 + glyoxal + succinate


name: 2 CoA + 2 H(+) + N(1),N(8)-bis(coumaroyl)-spermidine => 2 (E)-4-coumaroyl-CoA + spermidine


name: a cytidine(6-4)cytidine in DNA => a cytidine dimer in DNA + H(+)


name: 26-desgluco-avenacoside A + D-glucose => avenacoside A + H2O


name: H(+) + menaquinone-4 + NADH = menaquinol-4 + NAD(+)


name: PDE3A hydrolyses cAMP to AMP (Gallus gallus)


name: Transfer of NEDD8 to AcM-UBE2F (Canis familiaris)


name: 9H-carbazole + H(+) + NADPH + O2 => 2'-aminobiphenyl-2,3-diol + NADP(+)


name: 2,4-diacetylphloroglucinol + H2O <=> 2-acetylphloroglucinol + acetate


name: (Z)-glucobrassicin + adenosine 3',5'-bisphosphate + H(+) => (Z)-indolylmethyl desulfoglucosinolate + 3'-phosphoadenylyl sulfate


name: type 2 metabotropic glutamate receptor binding


name: an N-(acyl)-sphingosylphosphocholine => an N-(acyl)-sphingosyl-1,3-cyclic phosphate + choline


name: alpha,alpha-trehalose(out) + ATP + H2O = ADP + alpha,alpha-trehalose(in) + H(+) + phosphate


name: RAC1 and CDC42 activate PAK3 (Xenopus tropicalis)


name: CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 (Mus musculus)


name: 2-hydroxyisobutanoyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein]


name: ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Drosophila melanogaster)


name: dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] => CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: HJURP:CENPA complex localizes to the centromere (Bos taurus)


name: a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + O2 = a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + H2O + NAD(+)


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Rattus norvegicus)


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Mus musculus)


name: ATP + H(+) + NADPH + pentanoate <=> AMP + diphosphate + NADP(+) + pentanal


name: cholesterol + H(+) + NADPH + O2 => 26-hydroxycholesterol + H2O + NADP(+)


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Dictyostelium discoideum)


name: TP53 binds STK11 and NUAK1 (Rattus norvegicus)


name: H2O + L-arginine + O2 => 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: (3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) => [(3R)-hydroxybutanoate](n+1) + CoA


name: 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine => L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine


name: Phosphorylated OPTN translocates to the nucleus (Homo sapiens)


name: Fusion of early-endosome derived vesicles at the TGN (Mus musculus)


name: ferric triacetylfusarinine C transmembrane transporter activity


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Xenopus tropicalis)


name: H2O + nigerose = alpha-D-glucose + D-glucose


name: malonyl-CoA + S-adenosyl-L-methionine <=> malonyl-CoA methyl ester + S-adenosyl-L-homocysteine


name: GHRH receptor binds GHRH (Rattus norvegicus)


name: EPH:EFN tetramers oligomerise (Danio rerio)


name: a cholesterol ester + CoA => an acyl-CoA + cholesterol


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Homo sapiens)


name: "Catalysing the translocation of inorganic anions and their chelates"


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Drosophila melanogaster)


name: Generation of CLIP from lip10 (Rattus norvegicus)


name: CXXC1 and WDR82 bind SET1B complex (Drosophila melanogaster)


name: ATP + biotin + L-lysyl-[protein] <=> AMP + diphosphate + H(+) + N(6)-biotinyl-L-lysyl-[protein]


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Sus scrofa)


name: SPHK1 phosphorylates sphingoid (Mus musculus)


name: a fatty acid + glycerol + H(+) => a 1-acylglycerol + H2O


name: CARNMT1 methylates CARN to Anserine (Rattus norvegicus)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Schizosaccharomyces pombe)


name: SRD5A2 dehydrogenates TEST to DHTEST (Danio rerio)


name: chlorohydroquinone + 2 glutathione <=> chloride + glutathione disulfide + H(+) + hydroquinone


name: gibberellin A34 carboxyl methyltransferase activity


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Mus musculus)


name: PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: 17alpha-estradiol + NAD(+) => estrone + H(+) + NADH


name: CDK1 phosphorylates LBR (Rattus norvegicus)


name: COPI vesicle uncoating at the ER (Rattus norvegicus)


name: 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA => H(+) + isopentadecanoyl-CoA + L-serine


name: 4-aminobenzoate + AH2 + 2 O2 => 4-nitrobenzoate + A + 2 H2O


name: PAQR3 binds inactive RAFs (Xenopus tropicalis)


name: Connexin 62 mediated neuronal gap junction communication (Canis familiaris)


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Danio rerio)


name: USP13 deubiquitinates BECN1,USP10 (Homo sapiens)


name: Translocation of tBID to mitochondria (Xenopus tropicalis)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + sphing-4-enine => 1-O-alkyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine + H(+)


name: Activated FGFR3 phosphorylates PPTN11 (Bos taurus)


name: H2O + N(alpha)-acetyl-L-methionine <=> acetate + L-methionine


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Saccharomyces cerevisiae)


name: chloride(out) + D-tryptophan(out) + 2 Na(+)(out) <=> chloride(in) + D-tryptophan(in) + 2 Na(+)(in)


name: FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex (Bos taurus)


name: Synthesis of dolichyl-phosphate-glucose (Xenopus tropicalis)


name: scalarane-17alpha-19-diol => (2E,6E,10E,14E)-geranylfarnesol + H2O


name: MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) (Gallus gallus)


name: emodin + S-adenosyl-L-methionine = H(+) + questin + S-adenosyl-L-homocysteine


name: (3R)-hydroxytetradecanoate + H2O => H2O2 + tetradecanoate


name: p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Mus musculus)


name: chrysophanol-9-anthrone + O2 = chrysophanol + H2O


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Mus musculus)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Sus scrofa)


name: Formation of ADAR1 homodimer (Gallus gallus)


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA <=> (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H2O


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Mus musculus)


name: (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + H(+) + UDP => 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose


name: DAP12 interacts with NKG2C (Canis familiaris)


name: Sequestration of tBID by BCL-2 (Xenopus tropicalis)


name: RHOU binds effectors at the plasma membrane (Rattus norvegicus)


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Rattus norvegicus)


name: an alcohol + glutathione disulfide + H2O => a hydroperoxide + 2 glutathione


name: PTGFR binds PTGFR agonists (Danio rerio)


name: SHC1 binds to the phosphorylated EGF receptor:ligand complex (Rattus norvegicus)


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde <=> H(+) + H2O + quinolinate


name: MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Schizosaccharomyces pombe)


name: dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Xenopus tropicalis)


name: H(+) + NADPH + O2 + urate = 5-hydroxyisourate + H2O + NADP(+)


name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Saccharomyces cerevisiae)


name: [(1->4)-beta-D-glucosyl](n) + phosphate <=> [(1->4)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: CEBPB homodimerization (Drosophila melanogaster)


name: The p75NTR:NgR:MDGI binds RHOA-GDI (Sus scrofa)


name: (S)-dihydroorotate + a menaquinone <=> a menaquinol + orotate


name: ent-cassa-12,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = ent-3beta-hydroxycassa-12,15-dien-2-one + 3 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: PKA/PKG phosphorylate Rap1GAP2 (Drosophila melanogaster)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Saccharomyces cerevisiae)


name: Aquaporins passively transport water out of cells (Xenopus tropicalis)


name: SAMD8 transfers phosphatidyl from PE onto C16DH CER (Danio rerio)


name: angiotensin I + H2O = angiotensin-(1-9) + L-leucine


name: Beta-catenin translocates to the nucleus (Danio rerio)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Homo sapiens)


name: Gi/o-coupled serotonin receptor activity


name: all-trans-retinal + H2O + NAD(+) <=> all-trans-retinoate + 2 H(+) + NADH


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Homo sapiens)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Canis familiaris)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Plasmodium falciparum)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Mus musculus)


name: CHEK1 phosphorylates E2F6 (Homo sapiens)


name: dehydroepiandrosterone 3-sulfate(out) + n H(+)(out) => dehydroepiandrosterone 3-sulfate(in) + n H(+)(in)


name: GRB2:SOS interacts with p-KIT (Danio rerio)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus (Bos taurus)


name: (2S)-naringenin + dimethylallyl diphosphate => diphosphate + sophoraflavanone B


name: Proteasome mediated degradation of Cyclin D1 (Sus scrofa)


name: Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Rattus norvegicus)


name: 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one => 3-hydroxyhispidin + O2


name: 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 8,12-diethyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Gallus gallus)


name: 1,2-dichloroethane + H2O <=> 2-chloroethanol + chloride + H(+)


name: a ubiquinone + ethanol <=> a ubiquinol + acetaldehyde


name: 3'-AMP(out) + phosphate(in) = 3'-AMP(in) + phosphate(out)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + ATP


name: DENND3 exchanges GTP for GDP on RAB12 (Dictyostelium discoideum)


name: histamine + S-adenosyl-L-methionine <=> H(+) + N(tau)-methylhistamine + S-adenosyl-L-homocysteine


name: Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Sus scrofa)


name: SLC2A9 transports Fru, Glc, urate (Drosophila melanogaster)


name: PGE2 is converted to PGF2a by CBR1 (Canis familiaris)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Gallus gallus)


name: aniline + ATP + L-glutamate = ADP + N(5)-phenyl-L-glutamine + phosphate


name: Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors (Homo sapiens)


name: HRSP12 deaminates 2AA to 2OBUTA (Drosophila melanogaster)


name: The ABCC family mediates organic anion transport (Plasmodium falciparum)


name: D-sedoheptulose 7-phosphate = (R)-demethyl-4-deoxygadusol + H(+) + H2O + phosphate


name: TBC1D25 (OATL1) binds ATG8 homologues (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: Activation of MT-MMPs by FURIN (Drosophila melanogaster)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Bos taurus)


name: L-histidine(out) + Na(+)(out) => L-histidine(in) + Na(+)(in)


name: AMP + diphosphate + salicyl-[ACP] => ATP + holo-[ACP] + salicylate


name: Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Canis familiaris)


name: ATP + D-ribose 5-phosphate <=> 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Bos taurus)


name: 2'-deoxymugineate + 2-oxoglutarate + O2 => 3-epihydroxy-2'-deoxymugineate + CO2 + H(+) + succinate


name: beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = all-trans-zeaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Association of Emi1 with Cdh1 (Sus scrofa)


name: dehydroascorbic acid transmembrane transporter activity


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Bos taurus)


name: IKKbeta phosphorylates IkB causing NF-kB to dissociate (Bos taurus)


name: aldehydo-N-acetyl-D-mannosamine + ATP <=> ADP + H(+) + N-acetyl-D-mannosamine 6-phosphate


name: ERBB2 ECD mutants heterodimerize with EGFR (Homo sapiens)


name: dimethyl sulfoxide + H2O + NAD(+) <=> dimethyl sulfone + H(+) + NADH


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Mus musculus)


name: betaine aldehyde + H2O + NAD(+) <=> glycine betaine + 2 H(+) + NADH


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + 1D-myo-inositol 3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Bos taurus)


name: p-T,Y MAPK dimers translocate to nucleus (Plasmodium falciparum)


name: S2P hydrolyzes SREBP1A,1C,2 (Sus scrofa)


name: ATP + H2O + uroporphyrin III(in) <=> ADP + H(+) + phosphate + uroporphyrin III(out)


name: 4-hydroxyphenylacetate transmembrane transporter activity


name: miR-19b microRNA binds CNOT6L mRNA (Homo sapiens)


name: Haptoglobin-related Protein binds Hemoglobin (Mus musculus)


name: dammarenediol-II + UDP-alpha-D-glucose => (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + H(+) + UDP


name: HRASLS transfer acyl group from PC to PE to form NAPE (Homo sapiens)


name: O2 + 4 tellimagrandin II => 2 cornusiin E + 2 H2O


name: D-mannose + NADP(+) => 2-dehydro-D-glucose + H(+) + NADPH


name: 4-hydroxy-1-pyrroline-2-carboxylate + AH2 + H(+) => A + cis-4-hydroxy-D-proline


name: H(+) + N-tetracosanoyl-sphing-4-enine + phosphocholine => H2O + N-(tetracosanoyl)-sphing-4-enine-1-phosphocholine


name: Excision of FapyG by OGG1 glycosylase (Drosophila melanogaster)


name: a [peptide]-C-terminal amide + glyoxylate => a [peptide]-C-terminal (2S)-2-hydroxyglycine


name: Recruitment of CBL to KIT (Canis familiaris)


name: RNF8 and RNF168 ubiquitinate KDM4A,B (Mus musculus)


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Dictyostelium discoideum)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Rattus norvegicus)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Caenorhabditis elegans)


name: a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + a 5'-end dephospho-ribonucleoside-RNA = a ribonucleotidyl-ribonucleotide-RNA + GMP + H(+)


name: ME1 tetramer decarboxylates OA to PYR (Rattus norvegicus)


name: (+)-secoisolariciresinol + NADP(+) = (-)-lariciresinol + H(+) + NADPH


name: GDIs block activation of RHOA (Sus scrofa)


name: a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 + H(+) + UDP


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+) + hexadecanoate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Rattus norvegicus)


name: IL21 receptor JAK phosphorylation (Rattus norvegicus)


name: 2-oxospirilloxanthin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> 2,2'-dioxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: PPM1F dephosphorylates p-T286-CaMKII (Homo sapiens)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: TNFSF8 binds TNFRSF8 (Rattus norvegicus)


name: (6S)-5,6,7,8-tetrahydrofolate + syringate = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 3-O-methylgallate


name: H2O + sphing-4-enine 1-phosphate <=> phosphate + sphing-4-enine


name: Transfer of LPS onto TLR4 (Mus musculus)


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Saccharomyces cerevisiae)


name: ATP + folate(in) + H2O <=> ADP + folate(out) + H(+) + phosphate


name: PAX2 binds the PLAC8 gene (Homo sapiens)


name: Binding of pro-NGF to p75NTR:sortilin (Homo sapiens)


name: calmodulin-dependent protein phosphatase activity


name: 4 Fe(II)-[cytochrome c] + 4 H(+) + N2 => 4 Fe(III)-[cytochrome c] + hydrazine


name: (2R,3S)-2,4',7-trihydroxyisoflavanone = daidzein + H(+) + H2O


name: D-glucarate(in) + H(+)(in) = D-glucarate(out) + H(+)(out)


name: IL4:IL4R:JAK2 binds IL13RA1:TYK2 (Rattus norvegicus)


name: H(+) + menthone + NADPH + O2 => 7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+)


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Bos taurus)


name: a diacylglycerol + N-(28-(9Z,12Z-octadecadienoyloxy)-octacosanoyl)-sphing-4-enine => a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(28-hydroxyoctacosanoyl)-sphing-4-enine


name: 2-oxoglutarate + CO2 => (S)-oxalosuccinate + H(+)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in)


name: CD200 binds to CD200R (Rattus norvegicus)


name: (2Z,6E)-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphate


name: Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)


name: (9Z)-octadecenoate + H(+) + sn-glycero-3-phospho-(1'-sn-glycerol) => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O


name: 3'-phosphoadenylyl sulfate + bisphenol A <=> adenosine 3',5'-bisphosphate + bisphenyl A sulfate + H(+)


name: RUNX1 binds intron 1 of IL2RA (CD25) gene (Homo sapiens)


name: D-erythritol 1-phosphate + NADP(+) <=> D-erythrulose 1-phosphate + H(+) + NADPH


name: PLK1 phosphorylates GTSE1 (Canis familiaris)


name: ADP(in) + ATP(out) <=> ADP(out) + ATP(in)


name: Activated thrombin (factor IIa) cleaves PAR3,4, activating them (Canis familiaris)


name: inositol pentakisphosphate 2-kinase activity


name: 2-acyl LPE is acylated to PE by LPEAT (Sus scrofa)


name: butyl formate + H2O + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin] => butachlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Interaction of other adapter proteins with p-KIT (Gallus gallus)


name: cholesterol + hexadecanoyl-CoA => cholesteryl hexadecanoate + CoA


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Mus musculus)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Xenopus tropicalis)


name: I-Smad competes with Co-Smad for R-Smad1/5/8 (Rattus norvegicus)


name: Phosphorylated Cdc6 is exported from the nucleus (Saccharomyces cerevisiae)


name: Activation of RAC1 by VAV2/3 (Sus scrofa)


name: The keratan chain can be capped by N-acetylneuraminic acid (Mus musculus)


name: a 3beta-hydroxysteroid ester + a diacylglycerol => a 3beta-hydroxysteroid + a triacylglycerol


name: ALDH3A2-1 oxidises HD2NAL to PALM (Rattus norvegicus)


name: Activated FGFR4 phosphorylates PLCG1 (Sus scrofa)


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Bos taurus)


name: IL12A:IL12B translocates from late endosome lumen to extracellular region (Mus musculus)


name: ATP binding to HSP90 triggers conformation change (Sus scrofa)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Dictyostelium discoideum)


name: Activation of CHEK1 at resected DNA DSBs (Drosophila melanogaster)


name: Collagen type VII binds integrin alpha2beta1 (Xenopus tropicalis)


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Canis familiaris)


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Xenopus tropicalis)


name: sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity


name: DHCR7 reduces 7-dehydroCHOL to CHOL (Sus scrofa)


name: D-glucose 6-phosphate + GDP-alpha-D-glucose => alpha,alpha-trehalose 6-phosphate + GDP + H(+)


name: AH2 + GTP + S-adenosyl-L-methionine <=> 3'-deoxy-3',4'-didehydro-GTP + 5'-deoxyadenosine + A + H(+) + H2O + L-methionine


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Sus scrofa)


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Sus scrofa)


name: Autocatalytic activation of MMP7 (Sus scrofa)


name: 2alpha,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + testosterone


name: CASP9 is phosphorylated at T412 (Mus musculus)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Bos taurus)


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Xenopus tropicalis)


name: an N-acyl-L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine => a fatty acyl-[ACP] + S-adenosyl-L-methionine


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Homo sapiens)


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Mus musculus)


name: NF1 is degraded by the proteasome (Dictyostelium discoideum)


name: Hikeshi binds HSP70s:ATP (Saccharomyces cerevisiae)


name: LONP1 binds mitochondrial inner membrane proteins (Mus musculus)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Xenopus tropicalis)


name: CoA + hexadecanal + NAD(+) = H(+) + hexadecanoyl-CoA + NADH


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3) = beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: acetyl-CoA + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate = CoA + H(+) + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate


name: diphosphate + dUMP + NH4(+) => dCTP + 2 H2O


name: RUNX1 binds PRMT1 (Drosophila melanogaster)


name: (9Z)-octadecenoate + ethanol + H(+) => ethyl (9Z)-octadecenoate + H2O


name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Homo sapiens)


name: (R)-1-aminopropan-2-ol + adenosylcob(III)yrate + ATP => adenosylcob(III)inamide + ADP + H(+) + phosphate


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Rattus norvegicus)


name: SLC2A5 transports fructose from extracellular region to cytosol (Caenorhabditis elegans)


name: L-ascorbate + O2 + tyramine => (R)-octopamine + H2O + L-dehydroascorbate


name: 2xTRAP hydrolyzes FMN to RIB (Danio rerio)


name: H(+) + hnu + tetradecanoate <=> CO2 + tridecane


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Bos taurus)


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Xenopus tropicalis)


name: 2-oxoadipate + glycine => glyoxylate + L-2-aminoadipate


name: DEGS2 oxygenates dihydroceramide (Caenorhabditis elegans)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 = 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate


name: PIAS3 SUMOylates RELA with SUMO3 (Drosophila melanogaster)


name: gibberellin A19 + H(+) + O2 => CO2 + gibberellin A20 + H2O


name: D-maltohexaose + O2 = D-maltohexaono-1,5-lactone + H2O2


name: Cleavage of uracil by SMUG1 glycosylase (Drosophila melanogaster)


name: 2-oxoglutarate + a 5-methyl-2'-deoxycytidine in DNA + O2 => a 5-hydroxymethyl-2'-deoxycytidine in DNA + CO2 + succinate


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + acetyl-CoA <=> 1-O-(1Z)-alkenyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: MRE11 binds cytosolic DNA (Mus musculus)


name: dihydroxyacetone + H(+) + NADPH => glycerol + NADP(+)


name: PTK6 translocates to the nucleus (Sus scrofa)


name: AKT phosphorylates CREB1 (Gallus gallus)


name: 3-O-(beta-D-xylosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP => L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose


name: 3-hydroxybenzaldehyde + H(+) + NADPH => 3-hydroxybenzyl alcohol + NADP(+)


name: 13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+) = 15-oxoprostaglandin E1 + H(+) + NADPH


name: dihydroxyacetone + phosphoenolpyruvate => dihydroxyacetone phosphate + pyruvate


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Homo sapiens)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Rattus norvegicus)


name: MVB Vesicle Formation (Dictyostelium discoideum)


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na(+)(in) => 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na(+)(out)


name: butane-1-sulfonate + FMNH2 + O2 = butanal + FMN + 2 H(+) + H2O + sulfite


name: 1-O-alkyl-sn-glycerol + H(+) + phosphocholine => 1-O-alkyl-sn-glycero-3-phosphocholine + H2O


name: NOTCH1 HD domain mutants bind DLL1 (Homo sapiens)


name: H2O + O2 + pyridoxamine 5'-phosphate <=> H2O2 + NH4(+) + pyridoxal 5'-phosphate


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Sus scrofa)


name: 9-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Danio rerio)


name: gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling


name: 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H(+) => deacetylpyripyropene E


name: Activated JAK1 binds RAF1 (Mus musculus)


name: prunetin + UDP-alpha-D-glucuronate = prunetin-5-O-beta-D-glucuronide + UDP


name: NFE2L2 binds the TKT gene (Homo sapiens)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Rattus norvegicus)


name: H(+)(in) + shikimate(in) = H(+)(out) + shikimate(out)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Dictyostelium discoideum)


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Caenorhabditis elegans)


name: H(+) + NADPH + O2 + phenol = catechol + H2O + NADP(+)


name: 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity


name: Binding of the MCC complex to the APC/C complex (Sus scrofa)


name: (E)-caffeyl aldehyde + CoA + NADP(+) <=> (E)-caffeoyl-CoA + H(+) + NADPH


name: dUTP + H2O => dUMP + pyrophosphate (Saccharomyces cerevisiae)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADPH


name: 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O <=> (9Z)-octadecenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+)


name: 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP => (indol-3-yl)acetate + UDP-alpha-D-glucose


name: 4-coumaroyl-CoA + shikimate = CoA + trans-4-coumaroylshikimate


name: K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Mus musculus)


name: (3S)-hydroxytetradecanoyl-CoA + H2O = (3S)-hydroxytetradecanoate + CoA + H(+)


name: viral dsRNA: TLR3: TICAM1 recruits TRAF6 (Gallus gallus)


name: Activated FGFR2 phosphorylates FRS2 (Homo sapiens)


name: AXIN is phosphorylated in the destruction complex (Drosophila melanogaster)


name: Rap1 signal termination by Rap1GAPs (Canis familiaris)


name: mito-STARD7 transports Q10 to outer mitochondrial membrane (Rattus norvegicus)


name: glycoursodeoxycholate(out) + 2 Na(+)(out) = glycoursodeoxycholate(in) + 2 Na(+)(in)


name: pre-VLDL binds lipids to form VLDL (Sus scrofa)


name: Isomerization of GlcNAc6P to GlcNAc1P (Homo sapiens)


name: GNRHR binds GNRHR peptide antagonists (Caenorhabditis elegans)


name: SLC12A3 binds SLC12A3 inhibitors (Mus musculus)


name: LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm (Homo sapiens)


name: propane-1,2-diol => 1,2-epoxypropane + H2O


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+) => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP-beta-L-fucose


name: GLI translocates to the nucleus (Rattus norvegicus)


name: L-selenocysteinyl-tRNA(Sec) + 2 phosphate => H2O + O-phospho-L-seryl-tRNA(Sec) + selenophosphate


name: a 2-deoxy-alpha-D-glucoside + H2O => 2-deoxy-D-glucose + an alcohol


name: 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 => a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate


name: Re-integration of insulin receptor into plasma membrane (Bos taurus)


name: H2O + N(pros)-phospho-L-histidyl-[protein] = L-histidyl-[protein] + phosphate


name: n H(+)(out) + spermine(in) => n H(+)(in) + spermine(out)


name: Interaction of integrin alphaDbeta2 with fibrin (Sus scrofa)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Homo sapiens)


name: potassium ion transmembrane transporter activity


name: Reduction of desmosterol to cholesterol (Sus scrofa)


name: DLD dimer dehydrogenates dihydrolipoyl (Dictyostelium discoideum)


name: (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S,14S)-dihydroperoxy-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoate


name: beta-bisabolene + diphosphate => (2Z,6E)-farnesyl diphosphate


name: NLRX1 inhibits IPS1 signaling (Gallus gallus)


name: 4-nitrobenzaldehyde + H(+) + NADPH => 4-nitrobenzyl alcohol + NADP(+)


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Sus scrofa)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Mus musculus)


name: (2E)-tetracosenoyl-CoA + H(+) + NADH => NAD(+) + tetracosanoyl-CoA


name: TFIIIC-class transcription factor complex binding


name: Fibrillin-1 degradation by ELANE (Homo sapiens)


name: UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Danio rerio)


name: 2,4-dihydroxy 5,6-dimethylbenzaldehyde + AMP + diphosphate + NADP(+) => 5-methylorsellinate + ATP + H(+) + NADPH


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Mus musculus)


name: (E)-sinapyl alcohol + NADP(+) => (E)-sinapaldehyde + H(+) + NADPH


name: an N-(acyl)-sphingosylphosphocholine(in) + ATP + H2O = ADP + an N-(acyl)-sphingosylphosphocholine(out) + H(+) + phosphate


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Mus musculus)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA


name: Fe(III)-[cytochrome c] + H2O + nitric oxide <=> Fe(II)-[cytochrome c] + 2 H(+) + nitrite


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Canis familiaris)


name: Autocatalytic activation of MMP1 (Mus musculus)


name: AH2 + Fe(II)-heme i => A + Fe(II)-heme o + H2O


name: ornithine => putrescine + CO2 (Canis familiaris)


name: queuosine(34) in tRNA(Tyr) + UDP-alpha-D-galactose = H(+) + O-5''-beta-D-galactosylqueuosine(34) in tRNA(Tyr) + UDP


name: 6-O-demethylthebaine + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + O2 + thebaine


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + H2O <=> (4Z,15Z)-bilirubin IXalpha + D-glucuronate + H(+)


name: MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Homo sapiens)


name: 2-amino-5-chlorophenol + O2 <=> 2-amino-5-chloromuconate 6-semialdehyde


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Drosophila melanogaster)


name: TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Bos taurus)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Xenopus tropicalis)


name: a 2'-deoxyribonucleoside 5'-triphosphate + GDP => a 2'-deoxyribonucleoside 5'-diphosphate + GTP


name: TNF-alpha inhibitors bind to TNF(1-233) trimer (Sus scrofa)


name: (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + oxidized [electron-transfer flavoprotein] + valproyl-CoA


name: TGFBR2 phosphorylates TGFBR1 (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Mus musculus)


name: VEGFA-165 dimer binds VEGFR2 dimer (Danio rerio)


name: 4-amino-4-deoxy-beta-L-arabinopyranosyl-lipid A + di-trans,octa-cis-undecaprenyl phosphate => 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A


name: ESTG binds ESR1:chaperone complex (Gallus gallus)


name: (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H(+) + NADPH => (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + NADP(+)


name: ATP + L-threonyl-[receptor-protein] <=> ADP + H(+) + O-phospho-L-threonyl-[receptor-protein]


name: a dicarboxylate(in) + xanthurenate(out) = a dicarboxylate(out) + xanthurenate(in)


name: 2-O-sulfo-alpha,alpha-trehalose + octadecanoyl-CoA <=> 2-O-sulfo-2'-O-octadecanoyl-alpha,alpha-trehalose + CoA


name: Phosphorylation of JAK2 (Canis familiaris)


name: ADP + dimethylallyl diphosphate => diphosphate + N(6)-(dimethylallyl)adenosine 5'-diphosphate


name: (2E,6E,10E)-geranylgeraniol + ATP = (2E,6E,10E)-geranylgeranyl phosphate + ADP + H(+)


name: an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine => a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine


name: Activated protein C:PROCR binds F2R (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine => a 1-acyl-sn-glycero-3-phosphocholine + a 1-O-acyl-N-acylsphing-4-enine


name: (4R)-hydroxysphinganine + octadecanoyl-CoA = CoA + H(+) + N-octadecanoyl-(4R)-hydroxysphinganine


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Rattus norvegicus)


name: (2E)-triacontenoyl-CoA + H(+) + NADPH => NADP(+) + triacontanoyl-CoA


name: (R)-miconazole(in) + ATP + H2O => (R)-miconazole(out) + ADP + H(+) + phosphate


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: Autocatalytic activation of MMP7 (Drosophila melanogaster)


name: PIAS3 SUMOylates MITF with SUMO1 (Caenorhabditis elegans)


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane + H2O <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: (S)-2-hydroxyglutarate(out) + (S)-malate(in) => (S)-2-hydroxyglutarate(in) + (S)-malate(out)


name: MIR27B microRNA binds 3'UTR of TGFBR3 mRNA (Homo sapiens)


name: 4,4-dimethyl-8,14-cholestadien-3beta-ol + H(+) + NADPH = 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + NADP(+)


name: prostaglandin E1 <=> H2O + prostaglandin A1


name: RUNX1 binds the SWI/SNF complex (Gallus gallus)


name: a ganglioside GD1a (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GalNAc-GD1a (d18:1(4E)) + H(+) + UDP


name: H(+) + NAD(+) + reduced [4Fe-4S]/[3Fe-4S]-[ferredoxin] <=> NADH + oxidized [4Fe-4S]/[3Fe-4S]-[ferredoxin]


name: coenzyme F420-2 alpha-glutamyl ligase activity


name: 11-hydroxycucurbitadienol + O2 + reduced [NADPH--hemoprotein reductase] <=> 11-oxocucurbitadienol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-2,3-diaminopropanoate + ATP + citrate => 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + AMP + diphosphate


name: NADP(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Homo sapiens)


name: MITF-M-dependent TBX2 gene expression (Homo sapiens)


name: Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA (Xenopus tropicalis)


name: (5E)-tetradecenoyl-CoA + (R)-carnitine <=> (5E)-tetradecenoyl-(R)-carnitine + CoA


name: n H(+)(out) + pregnenolone sulfate(out) <=> n H(+)(in) + pregnenolone sulfate(in)


name: TFIIA-class transcription factor complex binding


name: H(+)(in) + L-aspartate(out) + phosphate(in) = H(+)(out) + L-aspartate(in) + phosphate(out)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Schizosaccharomyces pombe)


name: PROT mediates L-proline uptake (Rattus norvegicus)


name: Removal of fibrillar collagen N-propeptides (Sus scrofa)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + gamma-curcumene


name: MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)


name: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose => CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + H(+)


name: MKRN1 polyubiquitinates PTEN (Danio rerio)


name: 2 oxidized [2Fe-2S]-[ferredoxin] + protochlorophyllide a <=> 3,8-divinyl protochlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 3-dehydroshikimate <=> 3,4-dihydroxybenzoate + H2O


name: Association of procollagen type XI (Bos taurus)


name: CNIH1 binds TFGA and AREG precursors (Gallus gallus)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Homo sapiens)


name: 3 H(+) + H2O + urea-1-carboxylate => 2 CO2 + 2 NH4(+)


name: TGFBR3(1-783) binds to TGFB1,TGFB2 (Xenopus tropicalis)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Canis familiaris)


name: RAC1 GDIs block activation of RAC1 (Bos taurus)


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Danio rerio)


name: 4-nitrophenol + H(+) + NADPH + O2 => 4-nitrocatechol + H2O + NADP(+)


name: Activation of Ca2+ activated Potassium channels with large conductance (Homo sapiens)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Mus musculus)


name: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: 2-oxoglutarate + O2 + validoxylamine A => CO2 + H(+) + succinate + validoxylamine B


name: ANKLE2 binds PP2A (Caenorhabditis elegans)


name: 3-oxooctadecanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxyoctadecanoyl-[ACP] + NADP(+)


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Sus scrofa)


name: WWOX binds ERBB4s80 (Caenorhabditis elegans)


name: p-T182 MAPKAPK5 binds DNAJB1 (Sus scrofa)


name: carnitine + H(+) => 2-methylcholine + CO2


name: 1-O-alkyl-2-acyl-sn-glycerol + ATP <=> 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: KLK5 cleaves and activates KLK8 (Sus scrofa)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Caenorhabditis elegans)


name: ATP + beta-nicotinamide D-riboside <=> ADP + beta-nicotinamide D-ribonucleotide + H(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + triacontanoate = H(+) + H2O + omega-hydroxy-triacontanoate + oxidized [NADPH--hemoprotein reductase]


name: H2O + O2 + spermine = H2O2 + N-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine


name: Defective CYP17A1 does not 17-hydroxylate PREG (Homo sapiens)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP


name: very-low-density lipoprotein particle receptor binding


name: but-3-ynal + H(+) + pyrroloquinoline quinol = but-3-yn-1-ol + pyrroloquinoline quinone


name: 2 H(+) + hydrogen sulfide + sulfite + ubiquinone-10 => thiosulfate + ubiquinol-10


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Rattus norvegicus)


name: Elastin cross-linking by lysyl oxidase (Sus scrofa)


name: NCOA1 binds ESR1:estrogen:TGFA gene (Rattus norvegicus)


name: ECHS1 hydrates methacrylyl-CoA (Sus scrofa)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Danio rerio)


name: Defective pro-SFTPB does not translocate from ER membrane to multivesicle body (Homo sapiens)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Dictyostelium discoideum)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Caenorhabditis elegans)


name: L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[SCAN] => L-cysteinyl-[SCAN] + S-nitroso-L-cysteinyl-[protein]


name: a 1,2-diacyl-sn-glycerol + CDP-N,N-dimethylethanolamine => 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + CMP + H(+)


name: glycine transmembrane transporter activity


name: UBXN1 binds BRCA1:BARD1 heterodimer (Mus musculus)


name: GMP + H(+) + lactate => H2O + N(2)-(1-hydroxy-2-oxopropyl)-GMP


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)


name: 3-(indol-3-yl)lactate + NAD(+) => H(+) + indole-3-pyruvate + NADH


name: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] => a 2-hydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 Fe(III)-[cytochrome b5] + NADH => 2 Fe(II)-[cytochrome b5] + H(+) + NAD(+)


name: thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators (Sus scrofa)


name: (S)-3-methyl-2-oxopentanoate + H(+) + NADH + NH4(+) => H2O + L-isoleucine + NAD(+)


name: Trace amine-associated receptors can bind trace amines (Caenorhabditis elegans)


name: NADH + O2 + rifamycin SV = H2O + NAD(+) + rifamycin SV para-naphthoquinone carboxamide


name: CIT-3 binds activated RHOA, RHOB, RHOC and RAC1 (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR1b (Rattus norvegicus)


name: alpha-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase]


name: KEN dimer represses transcription (Drosophila melanogaster)


name: (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 3-[(E)-2-isocyanovinyl]indole + 2 CO2 + H2O + succinate


name: 2 H(+) + N,N-dimethylglycine + 2 S-adenosyl-L-homocysteine => glycine + 2 S-adenosyl-L-methionine


name: Aquaporins passively transport water out of cells (Dictyostelium discoideum)


name: FMNH2 + nitrilotriacetate + O2 <=> aminodiacetate + FMN + glyoxylate + H2O


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Rattus norvegicus)


name: 2-oxohexanoate + N(omega),N(omega)-dimethyl-L-arginine => 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminohexanoate


name: N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: UDP-alpha-D-glucose + vanillate = 1-O-(4-hydroxy-3-methoxybenzoyl)-beta-D-glucose + UDP


name: EGF-TM7 receptors bind chondroitin sulphate (Xenopus tropicalis)


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Homo sapiens)


name: cytidine(38) in tRNA + S-adenosyl-L-methionine = 5-methylcytidine(38) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: uridine(2819) in 21S rRNA = pseudouridine(2819) in 21S rRNA


name: a long-chain fatty acyl-CoA + AMP + diphosphate => a long-chain fatty acid + ATP + CoA


name: 2 Fe(III)-[cytochrome c] + H2O + trimethylamine => 2 Fe(II)-[cytochrome c] + 3 H(+) + trimethylamine N-oxide


name: monocarboxylic acid transmembrane transporter activity


name: H(+)(out) + L-phenylalanyl-L-leucine(out) <=> H(+)(in) + L-phenylalanyl-L-leucine(in)


name: NOX2 generates superoxide from oxygen (Canis familiaris)


name: GGCT transforms gGluCys to OPRO (Sus scrofa)


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Gallus gallus)


name: iodide(out) + 2 Na(+)(out) => iodide(in) + 2 Na(+)(in)


name: glucuronoxylan D-glucuronate + n S-adenosyl-L-methionine => glucuronoxylan 4-O-methyl-D-glucuronate + n H(+) + n S-adenosyl-L-homocysteine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: OPLAH hydrolyses OPRO to L-Glu (Dictyostelium discoideum)


name: 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate => 10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Bos taurus)


name: Phosphorylated STAT5 is released (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: (25R)-3-oxocholest-4-en-26-al + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25R)-3-oxocholest-4-en-26-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 1-O-alkyl-sn-glycero-3-phosphate + H2O => 1-O-alkyl-sn-glycerol + phosphate


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Rattus norvegicus)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + stellata-2,6,19-triene = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + stellatate


name: a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 (d18:1(4E)) + H(+) + UDP


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Mus musculus)


name: (5R,12R,14S)-dolasta-1(15),8-diene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: Alpha1-Microglobulin binds heme (Danio rerio)


name: 22-oxodocosanoate + H2O + NAD(+) => docosanedioate + 2 H(+) + NADH


name: a ganglioside GD3 + CMP-N-acetyl-beta-neuraminate = a ganglioside GT3 + CMP + H(+)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Defective TP53 does not tetramerize (Homo sapiens)


name: Bile salts and acids bind ALB (Xenopus tropicalis)


name: Sprouty sequesters CBL away from active EGFR (Drosophila melanogaster)


name: Phosphorylation of Bcl10 (Canis familiaris)


name: hydroxymethylbilane + 4 NH4(+) => H2O + 4 porphobilinogen


name: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Gallus gallus)


name: (3R)-hydroxytriacontanoyl-CoA <=> (2E)-triacontenoyl-CoA + H2O


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Danio rerio)


name: H2O + L-lysine + O2 = (S)-2-amino-6-oxohexanoate + H2O2 + NH4(+)


name: Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 (Homo sapiens)


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Mus musculus)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Mus musculus)


name: pyrimidine dimer DNA N-glycosylase activity


name: Glutamate synaptic vesicle docking and priming (Sus scrofa)


name: Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Canis familiaris)


name: 6-chloropyridine-2,3,5-triol + FADH2 + O2 = 3,6-dihydroxypyridine-2,5-dione + chloride + FAD + 3 H(+) + H2O


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Bos taurus)


name: acetoacetate + H(+) + naphthalene-1,3,6,8-tetrol => H2O + naphtopyrone YWA1


name: Binding of the MCC complex to the APC/C complex (Canis familiaris)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Danio rerio)


name: ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate


name: Exocytosis of platelet alpha granule contents (Schizosaccharomyces pombe)


name: ATP binds G-protein beta associated TRiC/CCT (Sus scrofa)


name: PDE6D dissociates from ARL13B:INPP5E (Sus scrofa)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Mus musculus)


name: D-xylono-1,5-lactone + H(+) + NADH => D-xylose + NAD(+)


name: MUC20 binds MET and inhibits GRB2 binding (Homo sapiens)


name: (E)-4-coumarate + H2O <=> 4-hydroxybenzaldehyde + acetate


name: Na(+)(in) + uracil(in) => Na(+)(out) + uracil(out)


name: (R)-mevalonate + NADP(+) => (R)-mevaldate + H(+) + NADPH


name: PHF8 demethylates histone H4K20me1 (Sus scrofa)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Danio rerio)


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Mus musculus)


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Schizosaccharomyces pombe)


name: 2-oxoglutarate + 5-aminopentanoate <=> 5-oxopentanoate + L-glutamate


name: Formation of the MLL3 complex (Caenorhabditis elegans)


name: LTC4 is exported from the cytosol by ABCC1 (Bos taurus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Bos taurus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2 H2O = 2 H(+) + 2 hexadecanoate + sn-glycerol 3-phosphocholine


name: N-methylnicotinate transmembrane transporter activity


name: MICAL1 produces NADP+, H2O2 (Gallus gallus)


name: CoA + H2O <=> (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Canis familiaris)


name: 4'-demethylrebeccamycin + H2O => beta-D-glucose + dichloroarcyriaflavin A


name: a 7beta-hydroxysteroid + NADP(+) = a 7-oxosteroid + H(+) + NADPH


name: Formation of histidino-hydroxylysinonorleucine cross-links (Canis familiaris)


name: FA2H hydroxylates 1,2-saturated fatty acids (Sus scrofa)


name: XDH oxidizes hypoxanthine to form xanthine (Homo sapiens)


name: beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA (Mus musculus)


name: acetyl-CoA + cyathin A3 = 11-O-acetylcyathin A3 + CoA


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Caenorhabditis elegans)


name: adenosine 2'-phosphate + H2O <=> adenosine + phosphate


name: L-tyrosine(in) + Na(+)(in) => L-tyrosine(out) + Na(+)(out)


name: Creatine transport across the plasma membrane (Mus musculus)


name: L-arginine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) <=> L-arginine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: (E)-4-hydroxynon-2-en-1-ol + NAD(+) = (E)-4-hydroxynon-2-enal + H(+) + NADH


name: Dissociation of Cdc20 from APC/C complex (Xenopus tropicalis)


name: (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 2 H(+) => (8S)-8-amino-7-oxononanoate + CO2 + L-lysyl-[protein]


name: GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Sus scrofa)


name: 1-acyl-sn-glycero-3-phospho-N-acyl-L-serine + a fatty acid + H(+) => 1,2-diacyl-sn-glycero-3-phospho-N-acyl-L-serine + H2O


name: Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Mus musculus)


name: Gbeta:gamma activation of PLC beta (Xenopus tropicalis)


name: OGDH dimer decarboxylates 2-OG (Saccharomyces cerevisiae)


name: Excess homocysteine yields homolanthionine and H2S (Rattus norvegicus)


name: (2E)-octenoate + 2 H(+) + NADH => (2E)-octenal + H2O + NAD(+)


name: Association of procollagen type XVII (Rattus norvegicus)


name: CTP + H(+) + N-methylethanolamine phosphate <=> CDP-N-methylethanolamine + diphosphate


name: Group 3 - Selective Cl- transport (Homo sapiens)


name: Association of procollagen type XVII (Mus musculus)


name: SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Mus musculus)


name: 4,4'-disulfanyldibutanoate + H(+) + NADH => 2 4-sulfanylbutanoate + NAD(+)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Mus musculus)


name: 5,10-dihydrophenazine 1-carboxylate + O2 = H2O2 + phenazine-1-carboxylate


name: dioscin + 3 H2O => D-glucose + diosgenin + 2 L-rhamnopyranose


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Saccharomyces cerevisiae)


name: D-xylose(out) + 2 Na(+)(out) = D-xylose(in) + 2 Na(+)(in)


name: 24-methylenecholesterol + UDP-alpha-D-glucose = 24-methylene cholesteryl beta-D-glucoside + H(+) + UDP


name: ACSF3 ligates CoA-SH to VLCFA (Drosophila melanogaster)


name: 1D-myo-inositol 1,3,4-trisphosphate + H2O <=> 1D-myo-inositol 3,4-bisphosphate + phosphate


name: ISGylation of PKR (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate + 7 isopentenyl diphosphate => all-trans-nonaprenyl diphosphate + 7 diphosphate


name: SeO3(2-) combines with GSH to form GSSeSG and GSSG (Homo sapiens)


name: eicosanoate + glycerol + H(+) => 1-eicosanoylglycerol + H2O


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-alpha-aminoacyl-[protein] => acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein]


name: Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region (Homo sapiens)


name: IL12 bound to IL12R internalises (Rattus norvegicus)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Canis familiaris)


name: guanosine(10) in tRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(10) in tRNA + S-adenosyl-L-homocysteine


name: (2E)-tetradecenoyl-CoA + H(+) + NADPH = NADP(+) + tetradecanoyl-CoA


name: D-cellotetraono-1,5-lactone + H2O = D-cellotetraonate + H(+)


name: IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Canis familiaris)


name: Recruitment of PAK to NCK (Homo sapiens)


name: 2-oxoglutarate + L-ornithine + O2 <=> (3S)-3-hydroxy-L-ornithine + CO2 + succinate


name: GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol (Dictyostelium discoideum)


name: PIAS1,3 SUMOylate NRIP1 with SUMO1 (Bos taurus)


name: SRC-1 phosphorylates PTK2-beta (Canis familiaris)


name: PalmS-ESRs:CAVs translocate to plasma membrane (Xenopus tropicalis)


name: Tropoelastin forms aggregate globules (Rattus norvegicus)


name: 2-oxoglutarate + a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + O2 = a 5'-end triphospho-guanosine-ribonucleotide-snRNA + CO2 + formaldehyde + H(+) + succinate


name: Ubiquitinated Orc1 is degraded by the proteasome (Bos taurus)


name: Binding of GRB2 to GAB1 (Xenopus tropicalis)


name: Interaction of SIGLEC14/15/16 and DAP12 (Homo sapiens)


name: H(+) + NADH + O2 + phenol = H2O + hydroquinone + NAD(+)


name: (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: LTBP1, LTBP3 bind TGF-Beta (Caenorhabditis elegans)


name: p-S MAPK6 phosphorylates NCOA3 (Xenopus tropicalis)


name: CCND1 binds RUNX3 and displaces EP300 (Rattus norvegicus)


name: Interaction of integrin alphaIIb beta3 with Fibrinogen (Danio rerio)


name: carbofuran + H(+) + H2O = 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol + CO2 + methylamine


name: RAN stimulates fusion of nuclear envelope (NE) membranes (Danio rerio)


name: Activation of RAC1 by VAV (Homo sapiens)


name: FAR2 reduces PalmCoA to HXOL (Bos taurus)


name: ethanol + 2 Fe(III)-[cytochrome c] = acetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: glycine betaine + H(+) + S-adenosyl-L-homocysteine => N,N-dimethylglycine + S-adenosyl-L-methionine


name: methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Homo sapiens)


name: Association of procollagen type XXI (Dictyostelium discoideum)


name: hexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 16-hydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Drosophila melanogaster)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Canis familiaris)


name: cis-stilbene oxide + H2O => (1R,2R)-hydrobenzoin


name: SLC22A12 exchanges extracellular urate for cytosolic LACT (Drosophila melanogaster)


name: 2 (3,4-dimethoxyphenyl)methanol + H2O2 <=> 2 (3,4-dimethoxyphenyl)methanol radical + 2 H2O


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Danio rerio)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Canis familiaris)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)


name: USP8 deubiquitinates STAM2:HGS (Homo sapiens)


name: amide transmembrane transporter activity


name: H2O + phosphoethanolamine <=> ethanolamine + phosphate


name: alizarin + UDP-alpha-D-glucose <=> 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP


name: abieta-7,13-dien-18,18-diol <=> abieta-7,13-dien-18-al + H2O


name: Polyubiquitination of substrate (Caenorhabditis elegans)


name: DSCAM/DSCAML1 homodimerization (Canis familiaris)


name: 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+)


name: IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Dictyostelium discoideum)


name: 26S proteasome degrades Ub-NFE2L2 (Drosophila melanogaster)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 5-hydroxy-L-tryptophan


name: CERK phosphorylates CERA to form C1P (Sus scrofa)


name: dodecanoyl-CoA + NAD(+) => (2E)-dodecenoyl-CoA + H(+) + NADH


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Danio rerio)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Bos taurus)


name: 4-prenylphlorisobutanophenone + dimethylallyl diphosphate = deoxycohumulone + diphosphate


name: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA => cyclohexa-1,5-diene-1-carbonyl-CoA + H2O


name: (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => L-tyrosine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + CO2 + CoA


name: ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA (Danio rerio)


name: a reduced flavin + NAD(+) = an oxidized flavin + 2 H(+) + NADH


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Mus musculus)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Plasmodium falciparum)


name: an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: acetyl-CoA transmembrane transporter activity


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Dictyostelium discoideum)


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Rattus norvegicus)


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Canis familiaris)


name: CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Bos taurus)


name: (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMNH2 + O2 <=> benzaldehyde + FMN + H(+) + H2O + N-acetyl-S-hydroxy-L-cysteine


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Canis familiaris)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Plasmodium falciparum)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Rattus norvegicus)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Gallus gallus)


name: Formation of Processive Complex (Schizosaccharomyces pombe)


name: CTP + H(+) + N(5)-phospho-L-glutamine => diphosphate + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine


name: 18-hydroxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] => aldosterone + 2 H2O + 2 oxidized [adrenodoxin]


name: FOXO1:PPARGC1A,FOXO4 binds PCK1 gene promoter (Homo sapiens)


name: p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Bos taurus)


name: glyoxylate + N(omega),N(omega)-dimethyl-L-arginine = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine


name: 2,4-dichlorophenol + H(+) + NADPH + O2 => 3,5-dichlorocatechol + H2O + NADP(+)


name: ESTG binds ESR1:chaperone complex (Drosophila melanogaster)


name: OPN (osteopontin) degradation by MMP3, MMP7 (Bos taurus)


name: 3-O-[N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + H(+) + UDP => L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: histidine => urocanate + NH4+ (Mus musculus)


name: ITCH polyubiquitinates TP73 (Danio rerio)


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Rattus norvegicus)


name: Co-precorrin-2 + 3 H(+) <=> Co(2+) + precorrin-2


name: 4-coumaroyl-CoA + shikimate => CoA + trans-4-coumaroylshikimate


name: Formation of the Flap Intermediate (Plasmodium falciparum)


name: Thrombin binding to GP1b:IX:V (Xenopus tropicalis)


name: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Bos taurus)


name: (S)-norreticuline + S-adenosyl-L-methionine = (S)-norcodamine + H(+) + S-adenosyl-L-homocysteine


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Canis familiaris)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Sus scrofa)


name: 2 AH2 + all-trans-zeta-carotene => 15-cis-phytoene + 2 A


name: apoTF binds 2Fe3+ to form holoTF (Gallus gallus)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-galactose


name: Fusion of COPII vesicle with Golgi complex (Sus scrofa)


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Danio rerio)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Bos taurus)


name: p-Y420-FYN is phosphorylated on S21 (Danio rerio)


name: RGGT:CHM binds RABs (Dictyostelium discoideum)


name: UDP(in) + UDP-alpha-D-glucuronate(out) = UDP(out) + UDP-alpha-D-glucuronate(in)


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Mus musculus)


name: Opioid receptors bind opioid peptides (Sus scrofa)


name: (13S)-edaxadiene + diphosphate => H2O + tuberculosinyl diphosphate


name: Tropoelastin forms aggregate globules (Gallus gallus)


name: GSDME (1-270) binds cardiolipin (Bos taurus)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Sus scrofa)


name: SPINK5(490-624) binds KLK5 (Mus musculus)


name: arginine + H2O => ornithine + urea [ARG2] (Bos taurus)


name: Acireductone is created (Caenorhabditis elegans)


name: (S)-lactate + oxaloacetate <=> (S)-malate + pyruvate


name: HSD17B3-like proteins reducde ANDST to TEST (Plasmodium falciparum)


name: 2 H(+) + NADH + O2 + precorrin-3A => H2O + NAD(+) + precorrin-3B


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Danio rerio)


name: (E)-gamma-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: (-)-menthyl beta-D-glucoside + H(+) + UDP => (-)-menthol + UDP-alpha-D-glucose


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Sus scrofa)


name: non-membrane spanning protein tyrosine kinase activity


name: Kinesin-3 is a dimer (Caenorhabditis elegans)


name: 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O => 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + phosphate


name: ITPA hydrolyses ITP to IMP (Schizosaccharomyces pombe)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecylglycerol => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol


name: CoA + H(+) + quercetin 3-O-[(6-O-[(E)-caffeoyl]-beta-D-glucosyl)-(1->2)-beta-D-glucoside] => (E)-caffeoyl-CoA + quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside


name: Collagen type XV restin release (Bos taurus)


name: USP8 deubiquitinates RNF128 (Canis familiaris)


name: beta-D-fructose 1,6-bisphosphate + H(+) + phosphate => beta-D-fructose 6-phosphate + diphosphate


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Mus musculus)


name: STAT1,STAT3 binds PKR (Xenopus tropicalis)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Mus musculus)


name: EP400 binds CDKN1A promoter (Rattus norvegicus)


name: diphosphate + phosphate + S-adenosyl-L-methionine => ATP + H2O + L-methionine


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Drosophila melanogaster)


name: PTP1B dephosphorylates GHR (Mus musculus)


name: Activation of conventional Protein Kinase C (Drosophila melanogaster)


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Dictyostelium discoideum)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Caspase-mediated cleavage of Desmoglein 3 (Homo sapiens)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + holo-[ACP] => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + dodecanoyl-[ACP]


name: (9Z,12Z)-octadecadienoate + 1-hexadecanoylglycerone 3-phosphate <=> 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate


name: (9Z)-octadecenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA


name: deoxycohumulone + dimethylallyl diphosphate <=> colupulone + diphosphate + H(+)


name: S-methyl-5-thio-D-ribulose 1-phosphate => S-methyl-1-thio-D-xylulose 5-phosphate


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Gallus gallus)


name: Translocation of activated BAX to the mitochondria (Rattus norvegicus)


name: ATP + D-lysine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate => ADP + H(+) + N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine + phosphate


name: (R)-3-hydroxybutanoate(out) + H(+)(out) <=> (R)-3-hydroxybutanoate(in) + H(+)(in)


name: (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H(+) + NADPH = (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + NADP(+)


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Mus musculus)


name: p-Y-STATs translocate to nucleus (Caenorhabditis elegans)


name: TDG excises 5-formylcytosine (Drosophila melanogaster)


name: [cypemycin](1-18)-L-Cys-L-Leu-L-Val-L-Cys + A => AH2 + C(3,19),S(21)-[cypemycin](1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide + CO2 + hydrogen sulfide


name: F8 variant does not bind the cell membrane (Homo sapiens)


name: DDX41 ubiquitination by TRIM21 (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + H2O = adenosine 3',5'-bisphosphate + 2 H(+) + S-(9Z-octadecenoyl)-4'-phosphopantetheine


name: Formation of translation initiation complexes containing mRNA that does not circularize (Saccharomyces cerevisiae)


name: CO2 + H2O + pentadecanal => (2R)-2-hydroperoxyhexadecanoate + H(+)


name: (R)-carnitine(out) + O-acetyl-(R)-carnitine(in) = (R)-carnitine(in) + O-acetyl-(R)-carnitine(out)


name: SLC9B1/C2 exchange Na+ for H+ (Sus scrofa)


name: EHMT1:EHMT2 dimethylates TP53 (Bos taurus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z-octadecenoate) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + cholesterol


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Plasmodium falciparum)


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate => CO2 + 2 H2O + NADP(+) + proviolacein


name: Ubiquitinated Orc1 is degraded by the proteasome (Plasmodium falciparum)


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Schizosaccharomyces pombe)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Bos taurus)


name: CD28 homodimer binds B7-2 monomer (Canis familiaris)


name: an N-terminal L-alpha-aminoacyl-[protein] + 3 S-adenosyl-L-methionine = an N-terminal trimethyl-L-alpha-aminoacyl-[protein] + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: (E)-2-methylgeranyl diphosphate + H2O = 2-methylisoborneol + diphosphate


name: KLK5 cleaves and activates CELA2 (Homo sapiens)


name: ILF3 binds PKR (Drosophila melanogaster)


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Sus scrofa)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)


name: SLC22A1 transports Cipro into renal cell (Sus scrofa)


name: Phosphorylated YBX1 translocates to the nucleus (Sus scrofa)


name: ORC1 translocates to the nucleus (Homo sapiens)


name: Abortive Initiation Before Second Transition (Drosophila melanogaster)


name: lecithin:11-cis retinol acyltransferase activity


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Schizosaccharomyces pombe)


name: Activated MET binds RANBP9 and SOS1 (Sus scrofa)


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Homo sapiens)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O => 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Caenorhabditis elegans)


name: (-)-pinoresinol + H(+) + NADPH => (-)-lariciresinol + NADP(+)


name: a carboxylate(in) + orotate(out) = a carboxylate(out) + orotate(in)


name: Initial activation of proMMP2 by MMP1, 7 (Mus musculus)


name: [protein]-disulfide + 2 glutathione => [protein]-dithiol + glutathione disulfide


name: 2-aminopentane + H2O + NAD(+) = H(+) + NADH + NH4(+) + pentan-2-one


name: 4alpha-carboxyzymosterol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formylzymosterol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O => 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Caenorhabditis elegans)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine => 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: NFKB1:RELA translocates from the cytosol to the nucleus (Bos taurus)


name: ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Mus musculus)


name: UDP-alpha-D-glucose + vanillate => 1-O-(4-hydroxy-3-methoxybenzoyl)-beta-D-glucose + UDP


name: chenodeoxycholate + NADP(+) <=> 7-oxolithocholate + H(+) + NADPH


name: (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + (3R)-all-trans-3-hydroxyretinal


name: (1S,2S)-OPC-8 + ATP + CoA <=> AMP + diphosphate + OPC8-CoA


name: MTMR4 dephosphorylates SMAD2/3 (Rattus norvegicus)


name: androstan-3alpha,17beta-diol + NAD(+) => 17beta-hydroxyandrostanone + H(+) + NADH


name: a ganglioside Fuc-GA1 + UDP-alpha-D-galactose <=> ganglioside Gal-(Fuc)-GA1 + H(+) + UDP


name: myo-inositol + S-adenosyl-L-methionine => 1D-4-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: (2S)-2-amino-3-oxobutanoate + H(+) + NADPH => L-allo-threonine + NADP(+)


name: Exocytosis of specific granule membrane proteins (Bos taurus)


name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Canis familiaris)


name: CoA + H(+) + N-acetyltyramine => acetyl-CoA + tyramine


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O <=> 2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: CYP19A1 hydroxylates ANDST to E1 (Canis familiaris)


name: 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose => 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Saccharomyces cerevisiae)


name: (24S)-hydroxycholesterol + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine = (24S)-hydroxycholesterol 3-linoleoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Bos taurus)


name: H2O + L-gulono-1,4-lactone <=> H(+) + L-gulonate


name: (9Z)-octadecenoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+) => 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O


name: 2 Fe(III)-[cytochrome c3] + H2 <=> 2 Fe(II)-[cytochrome c3] + 2 H(+)


name: ATM dimer:PEX5 phosphorylates PEX5 (Mus musculus)


name: LDLR:LDL complex => LDLR + LDL (Homo sapiens)


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Bos taurus)


name: beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp + H2O = alpha-D-mannopyranose + beta-D-mannopyranosyl-(1->2)-D-mannopyranose


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + succinate


name: L-tyrosine + NADPH + S-adenosyl-L-methionine <=> 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+)


name: RHOA:GTP binds ROCK, activating it (Mus musculus)


name: MAP2K1 phosphorylates MAPK3 (Bos taurus)


name: Fall Back to Closed Pre-initiation Complex (Mus musculus)


name: HNF1B- and FGF10-dependent synthesis of PTF1A protein (Homo sapiens)


name: a primary alcohol + 2 oxidized [azurin] => an aldehyde + 2 H(+) + 2 reduced [azurin]


name: L-alanine + taurocholate <=> L-alanocholate + taurine


name: DPP4 binds DPP4 inhibitors (Drosophila melanogaster)


name: acetyl-CoA + butanoyl-CoA => 3-oxohexanoyl-CoA + CoA


name: ERK1/2 phosphorylates MSK1 (Canis familiaris)


name: a 2,3-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA


name: magnesium protoporphyrin IX methyltransferase activity


name: 3',3'-c-di-GMP + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H(+)


name: luteothin + S-adenosyl-L-homocysteine => demethylluteothin + S-adenosyl-L-methionine


name: (11Z)-eicosenoyl-CoA + NADP(+) => (2E,11Z)-eicosadienoyl-CoA + H(+) + NADPH


name: Caspase mediated cleavage of BAP31 (Rattus norvegicus)


name: voltage-gated sodium channel activity involved in SA node cell action potential


name: A + H2O + isoquinoline <=> AH2 + isoquinolin-1(2H)-one


name: Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)


name: H2O + thymidine 3'-phosphate => phosphate + thymidine


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Dictyostelium discoideum)


name: 3'-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] <=> 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O <=> 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)


name: 9,9'-di-cis-zeta-carotene + 2 a quinone <=> 7,7',9,9'-tetra-cis-lycopene + 2 a quinol


name: 2-hydroxycyclohexan-1-one + H(+) + NADH => NAD(+) + trans-cyclohexane-1,2-diol


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Plasmodium falciparum)


name: 17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+) => 17beta-estradiol + 3'-phosphoadenylyl sulfate


name: acetyl-CoA + L-phenylalanine <=> CoA + H(+) + N-acetyl-L-phenylalanine


name: 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH => 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Homo sapiens)


name: H(+) + NADPH + zymosterone = NADP(+) + zymosterol


name: 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + D-glyceraldehyde 3-phosphate => beta-D-fructose 1,6-bisphosphate + methylglyoxal


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Danio rerio)


name: LMAN family proteins bind glycosylated cargo (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = (19R,20S)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Two DITs combine to form thyroxine (Canis familiaris)


name: a 1-acyl-sn-glycero-3-phosphate + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phosphate + H2O


name: Addition of the third nucleotide on the nascent transcript (Canis familiaris)


name: carnosine + H2O <=> beta-alanine + L-histidine


name: N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Drosophila melanogaster)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)


name: H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein] => aldehydo-D-glucose 6-phosphate + L-lysyl-[protein]


name: PIAS1 SUMOylates SAFB with SUMO1 (Sus scrofa)


name: TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Canis familiaris)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Homo sapiens)


name: D-glucose + indole-3-acetyl-1D-myo-inositol => 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol


name: KLRC1:KLRD1 heterodimer interacts with HLA-E (Gallus gallus)


name: cyanidin + UDP-alpha-D-galactose => cyanidin 3-O-beta-D-galactoside + H(+) + UDP


name: H2O + S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] => H(+) + L-cysteinyl-[protein] + lactate


name: 3-hydroxyphenylacetyl-CoA + H2O <=> 3-hydroxyphenylacetate + CoA + H(+)


name: Autocatalytic phosphorylation of FGFR1c (Canis familiaris)


name: 4-methylumbelliferone beta-D-glucuronate(in) + ATP + H2O => 4-methylumbelliferone beta-D-glucuronate(out) + ADP + H(+) + phosphate


name: Cleavage of ERBB4m80 by gamma-scretase complex (Rattus norvegicus)


name: 3-oxochol-4-en-22-oate + ATP + CoA = 3-oxochol-4-en-22-oyl-CoA + AMP + diphosphate


name: 3-oxochola-1,4-dien-22-oate + H(+) + NADH + O2 <=> 9alpha-hydroxy-3-oxochola-1,4-dien-22-oate + H2O + NAD(+)


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Bos taurus)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Caenorhabditis elegans)


name: a triacyl-sn-glycerol + H2O = a 1,2-diacyl-sn-glycerol + a fatty acid + H(+)


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Rattus norvegicus)


name: PP5 dephosphorylates RAF1 S338 (Rattus norvegicus)


name: (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) <=> 2,3-dihydroxy-p-cumate + H(+) + NADH


name: extracellularly glycine-gated chloride channel activity


name: GLRA:GLRB:Gly transports extracellular Cl- to cytosol (Homo sapiens)


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Canis familiaris)


name: 2 a ubiquinol + 4 H(+)(in) + O2(in) => 2 a ubiquinone + 4 H(+)(out) + 2 H2O(in)


name: (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate = sulfate + sulforaphane