name: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate = (+)-thujopsene + diphosphate


name: all-trans-retinal + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-retinol + O2 + reduced [NADPH--hemoprotein reductase]


name: MMP2,9 cleave EPHB (Caenorhabditis elegans)


name: a ubiquinone + formate + H(+) => a ubiquinol + CO2


name: RP2 activates the GTPase activity of ARL3 (Gallus gallus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + decanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-decanoyl-sn-glycerol + CoA


name: H(+)(in) + L-lyxopyranose(in) = H(+)(out) + L-lyxopyranose(out)


name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 (Danio rerio)


name: (6R)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)


name: Addition of nucleotides between position +11 and +30 (Caenorhabditis elegans)


name: betaine aldehyde + H2O + NAD(+) => glycine betaine + 2 H(+) + NADH


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Rattus norvegicus)


name: griseophenone D + S-adenosyl-L-methionine => griseophenone C + S-adenosyl-L-homocysteine


name: (3R)-hydroxy-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA = (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H2O


name: ARFGAPs stimulate ARF GTPase activity (Saccharomyces cerevisiae)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Schizosaccharomyces pombe)


name: alpha,alpha-trehalose 6-phosphate + H(+) + UDP => D-glucose 6-phosphate + UDP-alpha-D-glucose


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Homo sapiens)


name: TRPA1 tetramer binds TRPA1 antagonists (Canis familiaris)


name: pituitary adenylate cyclase activating polypeptide activity


name: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + oxidized dithiothreitol = 1,4-dithiothreitol + 2,3-epoxyphylloquinone


name: AKR1B1 reduces Glc to D-sorbitol (Homo sapiens)


name: 8 AMP + 8 diphosphate + 8 H(+) + PF1022C + 4 S-adenosyl-L-homocysteine => 3 (R)-3-phenyllactate + (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine


name: Autocatalytic phosphorylation of FGFR2c (Gallus gallus)


name: Interaction of DAP12 and CLM7 (Mus musculus)


name: ATP + ergothioneine(out) + H2O = ADP + ergothioneine(in) + H(+) + phosphate


name: AADAC deacetylates PHEN (Dictyostelium discoideum)


name: SCF:FBXL7 binds AURKA (Plasmodium falciparum)


name: desmethyl-dehydrogriseofulvin + S-adenosyl-L-methionine <=> dehydrogriseofulvin + H(+) + S-adenosyl-L-homocysteine


name: [DsbD protein]-dithiol + [thioredoxin]-disulfide = [DsbD protein]-disulfide + [thioredoxin]-dithiol


name: Mcm4,6,7 trimer forms and associates with the replication fork (Sus scrofa)


name: (S)-2-hydroxymethylglutarate = 2-methyleneglutarate + H2O


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Homo sapiens)


name: Activated PCLG1 dissociates from NTRK3 (Rattus norvegicus)


name: UDP-alpha-D-glucose + validoxylamine A = H(+) + UDP + validamycin A


name: L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: NH4(+) + urea-1-carboxylate => biuret + H2O


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ATP => [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + ADP


name: H(+) + NADPH + progesterone = 5beta-pregnan-3,20-dione + NADP(+)


name: citrate(in) + 2 Na(+)(in) => citrate(out) + 2 Na(+)(out)


name: A + rhodopin => (3E)-3,4-didehydrorhodopin + AH2


name: 7-chloro-L-tryptophan + chloride + FADH2 + O2 => 6,7-dichloro-L-tryptophan + FAD + 2 H2O


name: α1-agonists bind ADRA1A,B,D (Homo sapiens)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Mus musculus)


name: p-PKR dimer phosphorylates SNCA (Canis familiaris)


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Sus scrofa)


name: H(+) + H2O + S-methyl-5'-thioadenosine => NH4(+) + S-methyl-5'-thioinosine


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Canis familiaris)


name: H2O + psi-UMP => D-ribose 5-phosphate + uracil


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + nonanedioate => 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Canis familiaris)


name: NADH + sulfur => hydrogen sulfide + NAD(+)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Gallus gallus)


name: CHD1L is recruited to GG-NER site (Canis familiaris)


name: N-formyl-L-kynurenine => L-tryptophan + O2


name: SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 (Caenorhabditis elegans)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeraniol + ATP => (2E,6E,10E)-geranylgeranyl phosphate + ADP + H(+)


name: a fatty acid + a sterol + H(+) => a sterol ester + H2O


name: L-cysteine(out) + L-methionine(in) = L-cysteine(in) + L-methionine(out)


name: 4-phenylbutan-2-amine + H2O + NAD(+) => 4-phenylbutan-2-one + H(+) + NADH + NH4(+)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate => 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: 2-oxoglutarate + acetyl-CoA + H2O <=> (2R)-homocitrate + CoA + H(+)


name: SULT dimers sulfate APAP to APAP-SO3 (Homo sapiens)


name: RDH13 reduces atRAL to atROL (Rattus norvegicus)


name: (3R)-3-{[carboxy(hydroxy)methyl]amino}butanoate + CO2 + succinate => (3R)-3-[(carboxymethyl)amino]butanoate + 2-oxoglutarate + O2


name: Oligomerization of BCL10 and MALT1 (Canis familiaris)


name: PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Homo sapiens)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)


name: COP9 and TOR1 deneddylate STON2 (Canis familiaris)


name: 16alpha-hydroxyestrone + UDP-alpha-D-glucuronate <=> 16alpha-hydroxyestrone 16-O-(beta-D-glucuronate) + H(+) + UDP


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Plasmodium falciparum)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Gallus gallus)


name: TRPV1 binds TRPV1 blockers (Gallus gallus)


name: H(+) + H2O2 + pyruvate => H2O + methylglyoxal + O2


name: CDK2 phosphorylates RBBP8 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ATP + H2O <=> a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: Phosphorylation of H2AX at S139 by ATM at the site of DSB (Gallus gallus)


name: c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)


name: AH2 + O2 + preaustinoid A = A + H2O + preaustinoid A1


name: CTP + H(+) + keto-D-fructose 6-phosphate <=> CDP-6-keto-D-fructose + diphosphate


name: 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-adenosine) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA => (9Z)-octadecenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: (2S)-naringenin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (2S)-dihydrotricetin + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: PCK1 phosphorylates OA to yield PEP (Bos taurus)


name: SARS-CoV-1 S binds SFTPD 12mer (Homo sapiens)


name: biotin + H2O + NAD(+) => biotinate sulfoxide + H(+) + NADH


name: A + cannabinerolate <=> AH2 + cannabichromenate


name: trehalose transmembrane transporter activity


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)


name: ADP + H(+) + N-acetyl-D-galactosamine 6-phosphate => ATP + N-acetyl-D-galactosamine


name: MITF-M dimer binds the PMEL gene (Homo sapiens)


name: SREBP1A,1C,2 translocates to the nucleus (Xenopus tropicalis)


name: IER3 recruits MAPKs to PP2A-B56-beta,gamma (Sus scrofa)


name: 3,4-dihydroxybenzaldehyde + AH2 + tyramine <=> A + H2O + norbelladine


name: chloride + FADH2 + ilicicolin B + O2 => FAD + H(+) + 2 H2O + ilicicolin A


name: RUNX2 and SMAD1 complex binds the SMAD6 gene promoter (Homo sapiens)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Rattus norvegicus)


name: 4-(methylamino)butanoate + H2O + O2 <=> H2O2 + methylamine + succinate semialdehyde


name: Binding of APOBEC-1 to form editosome (Sus scrofa)


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H(+) + NADH = 4-pyridoxate + NAD(+)


name: Ferriheme dissociates from p-T-EIF2AK1:2xferriheme dimer (Homo sapiens)


name: 2xPDKX:2xZn2+ phosphorylates PDX (Danio rerio)


name: Formation of collagen fibrils (Xenopus tropicalis)


name: (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + CO2 + CoA => (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + malonyl-CoA


name: H2O + N-(long-chain fatty acyl)ethanolamine <=> a long-chain fatty acid + ethanolamine


name: histone H3K37 methyltransferase activity


name: 3'-N-debenzoyltaxol + A + H2O => 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2


name: peonidin + UDP-alpha-D-glucose <=> peonidin 3-O-beta-D-glucoside + UDP


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Bos taurus)


name: H2O + N(omega)-alpha-(ADP-D-ribosyl)-L-arginyl-[dinitrogen reductase] => ADP-D-ribose + L-arginyl-[dinitrogen reductase]


name: (S)-1-pyrroline-5-carboxylate + H(+) + H2O => trans-4-hydroxy-L-proline


name: all-trans-retinyl hexadecanoate + H2O => all-trans-retinol + H(+) + hexadecanoate


name: UBA1 adenylates ubiquitin in the nucleoplasm (Homo sapiens)


name: genistein + O2 + reduced [NADPH--hemoprotein reductase] = 2'-hydroxygenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Sus scrofa)


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (Mus musculus)


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Mus musculus)


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Plasmodium falciparum)


name: Neurolysin degrades neurotensin (Sus scrofa)


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NAD(+) <=> (2S)-2-acetolactate + H(+) + NADH


name: (2S)-3-sulfolactaldehyde + H2O + NADP(+) = (2S)-3-sulfolactate + 2 H(+) + NADPH


name: Caspase mediated cleavage of beta-catenin (Rattus norvegicus)


name: Crk's SH3 domain engages C3G (Bos taurus)


name: 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+) => 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O2


name: Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid (Homo sapiens)


name: Formation of fatty acid synthase (FAS) dimer (Dictyostelium discoideum)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: Synthesis of negative sense genomic RNA of respiratory syncytial virus (Homo sapiens)


name: pregnenolone + UDP-alpha-D-glucose = H(+) + pregnenolone 3-beta-D-glucoside + UDP


name: Defective HLCS does not biotinylate PC:Mn2+ (Homo sapiens)


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Gallus gallus)


name: ligand-gated monoatomic ion channel activity


name: 2-methylpropanoyl-CoA + H(+) + malonyl-[ACP] => 4-methyl-3-oxopentanoyl-[ACP] + CO2 + CoA


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Gallus gallus)


name: SULT1A3,4 dimers sulfate DA to DAOS (Mus musculus)


name: Activation of RAC1 by VAV2/3 (Xenopus tropicalis)


name: Displacement of C2a/Bb by CR1 (Gallus gallus)


name: galactitol + NAD(+) <=> H(+) + keto-D-tagatose + NADH


name: NAD(+) + taurocholate <=> 7-oxo-taurodeoxycholate + H(+) + NADH


name: 5-hydroxymethyl-dUMP in DNA + ATP <=> 5-phosphomethyl-dUMP in DNA + ADP + H(+)


name: acetyl-CoA + cysteamine => CoA + S-acetylcysteamine


name: ent-copalyl diphosphate <=> diphosphate + ent-sandaracopimara-8(14),15-diene


name: Recruitment of clathrin coated vesicle by Ii (Sus scrofa)


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Rattus norvegicus)


name: Interaction of DAP12 and MDL-1 (Canis familiaris)


name: 3-dehydro-4alpha-methylzymosterol + H(+) + NADPH = 4alpha-methylzymosterol + NADP(+)


name: 3xPPCDC:3FMN decarboxylates PPC (Caenorhabditis elegans)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Danio rerio)


name: Formation of Cyclin B:Cdc2 complexes (Gallus gallus)


name: L-glutamine(in) + L-valine(out) + Na(+)(out) => L-glutamine(out) + L-valine(in) + Na(+)(in)


name: EGFR activates PLC-gamma1 by phosphorylation (Mus musculus)


name: RAC1:GTP binds NOX3 complex (Canis familiaris)


name: DHODH:FMN binds DHODH inhibitors (Caenorhabditis elegans)


name: H(+) + S-adenosyl-L-methionine => CO2 + S-adenosyl 3-(methylsulfanyl)propylamine


name: L-serine + phosphate => H2O + O-phospho-L-serine


name: S-adenosyl-L-homocysteine + velutin => chrysoeriol + S-adenosyl-L-methionine


name: 2-oxoglutarate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + L-glutamate


name: methylammonium transmembrane transporter activity


name: FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling (Bos taurus)


name: MET phosphorylates CBL (Canis familiaris)


name: Cleavage of uracil by MBD4 glycosylase (Xenopus tropicalis)


name: NR1H4 binds DCA, CDCA, LCHA (Mus musculus)


name: ent-kaur-16-en-19-al + O2 + reduced [NADPH--hemoprotein reductase] => ent-kaur-16-en-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CoA + H(+) + N-(2-hydroxyoctadecanoyl)-sphinganine => 2-hydroxyoctadecanoyl-CoA + sphinganine


name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex (Gallus gallus)


name: eIF2:GTP is hydrolyzed, eIFs are released  (Schizosaccharomyces pombe)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Xenopus tropicalis)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Bos taurus)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Bos taurus)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Danio rerio)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Mus musculus)


name: RXRA:PPARD binds FABP5:atRA (Xenopus tropicalis)


name: gibberellin A24 + H(+) + O2 => CO2 + gibberellin A9 + H2O


name: OMA1 hydrolyzes YME1L1 (Saccharomyces cerevisiae)


name: lochnericine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + horhammericine + oxidized [NADPH--hemoprotein reductase]


name: TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Homo sapiens)


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Gallus gallus)


name: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + ATP + CoA <=> [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + AMP + diphosphate


name: PLEKHA3,8 bind PI4P, ARF1 (Homo sapiens)


name: Protein Kinase B/Akt phosphorylates BRF1 (Rattus norvegicus)


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Xenopus tropicalis)


name: PAK1 or PAK2 phosphorylates MYLK (Gallus gallus)


name: 3-indoleglycolaldehyde + CO2 + NH4(+) => H(+) + L-tryptophan + O2


name: STAT1,STAT3,STAT6 phosphorylation (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> diphosphate + hydropyrenol


name: L1 interaction with Integrins (Caenorhabditis elegans)


name: ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Dictyostelium discoideum)


name: GOT2 dimer deaminates L-Asp (Rattus norvegicus)


name: Nucleotide exchange on RAB1 (Drosophila melanogaster)


name: L-asparaginyl-[protein] + NAD(+) = H(+) + N(4)-(ADP-D-ribosyl)-L-asparaginyl-[protein] + nicotinamide


name: (4R)-limonene + A + H2O <=> (4R)-perillyl alcohol + AH2


name: CDK2:CCNA phosphorylates TERF2 (Xenopus tropicalis)


name: PLB1 hydrolyses RPALM to atROL (Caenorhabditis elegans)


name: ADP + H(+) + L-cystine(in) + phosphate => ATP + H2O + L-cystine(out)


name: FLIP(S) and procaspase-8 form heterodimer (Rattus norvegicus)


name: JNK phosphorylates BIM, BAD and other targets (Homo sapiens)


name: ITPA hydrolyses XTP to XMP (Mus musculus)


name: 5,10-dihydrophenazine + O2 <=> H2O2 + phenazine


name: Activated FGFR4 phosphorylates SHC1 (Mus musculus)


name: DKC1 binds SHQ1 (Saccharomyces cerevisiae)


name: DDR2 binds collagen type I, II, III, V, X fibrils (Homo sapiens)


name: a CDP-1,2-diacyl-sn-glycerol + myo-inositol => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)


name: (6aR,11aR)-3,9-dihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] => (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Recruitment of VAV and BTK to p-SLP-76 (Rattus norvegicus)


name: ADH5 oxidises S-HMGSH to S-FGSH (Bos taurus)


name: IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Bos taurus)


name: H2O + N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)


name: DNA polymerase alpha:primase binds at the origin (Canis familiaris)


name: p-Y701-STAT1 binds p-Y705-STAT3 (Sus scrofa)


name: ATP + D-erythronate => 4-phospho-D-erythronate + ADP + H(+)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: (R)-noradrenaline(out) + chloride(out) + Na(+)(out) <=> (R)-noradrenaline(in) + chloride(in) + Na(+)(in)


name: H2O + NADP(+) + pentyl acetate => H(+) + heptan-2-one + NADPH + O2


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) <=> (2S)-2-acetolactate + H(+) + NADPH


name: IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)


name: H(+)(in) + L-rhamnopyranose(in) <=> H(+)(out) + L-rhamnopyranose(out)


name: PITPNM1,2,3 exchange PI for PA (Dictyostelium discoideum)


name: L-Leu-L-Met-NH2 + substance P(1-9) => H2O + substance P


name: prephenate + S-adenosyl-L-methionine = 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O


name: D-glucose + vomilenine => H2O + raucaffricine


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Rattus norvegicus)


name: Sema3A binds Nrp-1 bound to PlexinA (Rattus norvegicus)


name: hexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 26-hydroxyhexacosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Mus musculus)


name: The addition of GalNAc to the terminal glucuronate residue forms chondroitin (Homo sapiens)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate + H(+) => a cardiolipin + H2O


name: (3R)-hydroxy-(15Z)-tetracosenoyl-CoA = (2E,15Z)-tetracosadienoyl-CoA + H2O


name: MEMO1 binds RHOA:GTP:DIAPH1 (Canis familiaris)


name: Recruitment of CDK11p58 to the centrosomes (Canis familiaris)


name: Formation of ORC(1-5) complex (Bos taurus)


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Bos taurus)


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Bos taurus)


name: 1',3'-bis[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O => (9Z)-octadecenoate + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H(+)


name: RNA endonuclease activity, producing 3'-phosphomonoesters


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Caenorhabditis elegans)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Homo sapiens)


name: H(+) + malvidin 3-O-beta-D-galactoside + UDP => malvidin + UDP-alpha-D-galactose


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Drosophila melanogaster)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O = (9Z,12Z)-octadecadienoate + 2,3-di-(9Z,12Z)-octadecadienoyl-sn-glycerol + H(+)


name: p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)


name: 1-butyrylglycerol + H2O = butanoate + glycerol + H(+)


name: Dopa is oxidized to dopaquinone by TYR (Canis familiaris)


name: TFAP2C homodimer binds MYC and KDM5B (Gallus gallus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O => (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H(+)


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA2 (d18:1(4E)/18:0) => CMP + ganglioside GM2 (d18:1(4E)/18:0) + H(+)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O


name: LEAP2 binds bacteria (Rattus norvegicus)


name: acetate + succinyl-CoA <=> acetyl-CoA + succinate


name: 3-hydroxy-L-kynurenine + pyruvate = 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-alanine


name: 2 L-ascorbate + O2 = 2 H2O + 2 L-dehydroascorbate


name: 2-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate = 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: 3-sulfanylpentan-1-ol-L-cysteine + H2O = 3-sulfanyl-1-pentanol + NH4(+) + pyruvate


name: ATP + L-seryl-[Goodpasture antigen-binding protein] = ADP + H(+) + O-phospho-L-seryl-[Goodpasture antigen-binding protein]


name: L-cystine(out) + L-glutamate(in) => L-cystine(in) + L-glutamate(out)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Danio rerio)


name: an L-N,N-dihydroxypolyhomomethionine + H(+) = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + H2O


name: Homodimerization of VEGF proteins (Rattus norvegicus)


name: (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 => 3-[(Z)-2-isocyanoethenyl]-1H-indole + 2 CO2 + H2O + succinate


name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid (Homo sapiens)


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Homo sapiens)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Rattus norvegicus)


name: TRIM25 binds monoUb:164-PCNA (Homo sapiens)


name: UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b (Homo sapiens)


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) (Canis familiaris)


name: (R,R)-chrysanthemyl diphosphate + diphosphate => 2 dimethylallyl diphosphate


name: neamine + UDP-alpha-D-kanosamine = H(+) + kanamycin B + UDP


name: H(+) + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine


name: Association of Emi1 with Cdc20 (Sus scrofa)


name: Dissociation of RAS:RAF complex (Mus musculus)


name: Syndecans 2, (4) bind TGFB1 (Bos taurus)


name: Formation of ERCC1:XPF heterodimeric complex (Rattus norvegicus)


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Gallus gallus)


name: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Gallus gallus)


name: factor VII -> factor VIIa (Xenopus tropicalis)


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Caenorhabditis elegans)


name: dichloromethane + H2O = 2 chloride + formaldehyde + 2 H(+)


name: a 2-acylglycerol + an acyl-CoA <=> a 1,2-diacyl-sn-glycerol + CoA


name: (3R)-3,4-epoxy-3-methylbut-1-ene + glutathione => 2-glutathionyl-2-methylbut-3-en-1-ol


name: CYP51A1 demethylates LNSOL (Homo sapiens)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Schizosaccharomyces pombe)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Sus scrofa)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Homo sapiens)


name: DHRS7B reduces GO3P to HXDG3P (Danio rerio)


name: DHAP is converted to 1-acyl GO3P by GNPAT (Homo sapiens)


name: RNF181 polyubiquinates BCL10 (Sus scrofa)


name: SCF-FBXL7 ubiquitinates AURKA (Gallus gallus)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Bos taurus)


name: a 1-acyl-sn-glycerol + ATP => a 1-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: (E)-caffeoyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] = CoA + myricetin 3-O-[(6-O-(E)-caffeoyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Homo sapiens)


name: Mitochondrial BTD hydrolyses BCTN (Sus scrofa)


name: H2O + S-methyl-5'-thioadenosine => 5-(methylsulfanyl)-D-ribose + adenine


name: 2',3'-cUAMP + 2 diphosphate => ATP + UTP


name: AICAR + 10-Formyl-THF => FAICAR + THF (Drosophila melanogaster)


name: Proton-coupled histidine and di-peptide cotransport (Gallus gallus)


name: a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate


name: 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)


name: OCT1 transports organic cations into hepatic cells (Bos taurus)


name: CNRs bind CNR agonists (Canis familiaris)


name: CoA + ethyl 2-methylbutanoate => 2-methylbutanoyl-CoA + ethanol


name: IRF2 or IRF1 binds the GSDMD gene promoter (Homo sapiens)


name: quercetin gentiotrioside 1,6-glucosyltransferase activity


name: myo-inositol + O2 = D-glucuronate + H(+) + H2O


name: p-S216-CDC25C translocates to the cytosol (Bos taurus)


name: AKR1C1 hydrogenates PREDN,PREDL (Caenorhabditis elegans)


name: FAICAR => IMP + H2O (Caenorhabditis elegans)


name: Phosphorylation of SLP-76 by p-SYK (Gallus gallus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Saccharomyces cerevisiae)


name: Hh processing variants are translocated to the cytosol in a VCP-dependent manner (Homo sapiens)


name: (2R,3S)-dihydrodehydrodiconiferyl alcohol + H(+) + NADPH = (S)-tetrahydrodehydrodiconiferyl alcohol + NADP(+)


name: LINC01139 promotes phosphorylation of HIF1A by PTK6 (Sus scrofa)


name: (24S)-7alpha-dihydroxycholesterol + NAD(+) = (24S)-7alpha,24-dihydroxycholest-4-en-3-one + H(+) + NADH


name: a 3-oxoacyl-[ACP] + acetyl-[ACP] + H2O = a 3-carboxymethyl-3-hydroxy-acyl-[ACP] + H(+) + holo-[ACP]


name: UDP-alpha-D-glucose + vitexin <=> H(+) + UDP + vitexin 2''-O-beta-D-glucoside


name: 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Dictyostelium discoideum)


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Danio rerio)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Canis familiaris)


name: SMO translocates to the cilium (Canis familiaris)


name: VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization (Rattus norvegicus)


name: Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Sus scrofa)


name: D-xylotriono-1,5-lactone + H2O <=> D-xylotrionate + H(+)


name: (E)-sinapate + ATP + H(+) => (E)-sinapoyl-AMP + diphosphate


name: SMAD7 binds to SMURF2 (Rattus norvegicus)


name: SMAD3 binds STUB1 (CHIP) (Drosophila melanogaster)


name: butanal + H2O + NADP(+) = butanoate + 2 H(+) + NADPH


name: GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Danio rerio)


name: acetate + ATP + H(+) = acetyl-AMP + diphosphate


name: PRKCB (PKC-beta) phosphorylates CARMA1 (Canis familiaris)


name: AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Drosophila melanogaster)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Canis familiaris)


name: LARG binds plexin B1 (Drosophila melanogaster)


name: Phosphorylation of PKC theta (Saccharomyces cerevisiae)


name: PIAS4 SUMOylates VDR with SUMO2 (Homo sapiens)


name: flavanone 7-O-beta-D-glucoside + UDP-beta-L-rhamnose => flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] + H(+) + UDP


name: AVPR1A,B bind desmopressin (Homo sapiens)


name: Separation of elongating transcript from template (Bos taurus)


name: OCT3 mediates renal clearance of organic cations (Rattus norvegicus)


name: Formation of ADAR1 homodimer (Homo sapiens)


name: ALDH4A1 oxidises L-GluSS to Glu (Danio rerio)


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Mus musculus)


name: ABHD4 hydrolyses NAPE (Rattus norvegicus)


name: THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)


name: a ubiquinone + ethanol = a ubiquinol + acetaldehyde


name: TGFBR2 phosphorylates TGFBR1 (Bos taurus)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Caenorhabditis elegans)


name: Defective B3GALTL does not transfer glucose to O-fucosyl-proteins (Homo sapiens)


name: DPP4 binds DPP4 inhibitors (Saccharomyces cerevisiae)


name: p-PKR dimer phosphorylates ILF3:ILF2 (Drosophila melanogaster)


name: ATP + H2O + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(in) <=> ADP + H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(out) + phosphate


name: LIN7, CASK and APBA1 bind (Xenopus tropicalis)


name: LHPP:Mg2+ dimer hydrolyses PPi (Caenorhabditis elegans)


name: (2S)-3-phenyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2 => N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2


name: H2O + norlichexanthone => 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + H(+)


name: ATP + shikimate = 3-phosphoshikimate + ADP + H(+)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Bos taurus)


name: (2E)-dodecenoyl-CoA + H(+) + NADPH => dodecanoyl-CoA + NADP(+)


name: H2O + sphinganine 1-phosphate = phosphate + sphinganine


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Bos taurus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Drosophila melanogaster)


name: MARC1,MARC2 reduce N-hydroxylated compounds (Bos taurus)


name: RAC3 binds effectors at the plasma membrane (Dictyostelium discoideum)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Mus musculus)


name: 4-methylsulfanyl-2-oxobutanoate + acetyl-CoA + H2O = 2-(2-methylsulfanyl)ethylmalate + CoA + H(+)


name: ATP + glutathione + glutathionylspermidine => ADP + H(+) + phosphate + trypanothione


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Rattus norvegicus)


name: prunetin + UDP-alpha-D-glucuronate <=> prunetin-4'-O-beta-D-glucuronide + UDP


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Caenorhabditis elegans)


name: IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Sus scrofa)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Bos taurus)


name: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH


name: L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate => H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate


name: H2O + N-(dodecanoyl)-sphinganine <=> dodecanoate + sphinganine


name: (9Z,12Z)-octadecadienoate + 1,3-di-(9Z,12Z)-octadecadienoylglycerol + H(+) => 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Rattus norvegicus)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Canis familiaris)


name: 1,8-cineole + O2 + reduced [NADPH--hemoprotein reductase] = 2-exo-hydroxy-1,8-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) <=> (6R)-L-erythro-6,7-dihydrobiopterin + H(+) + NADPH


name: 4-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => estrone + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-hydroxylimonen-2-one + H(+) + NADPH + O2 = 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: indole-3-pyruvate + L-phenylalanine => 3-phenylpyruvate + L-tryptophan


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Canis familiaris)


name: ATP + L-threonine <=> ADP + H(+) + O-phospho-L-threonine


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Sus scrofa)


name: GP1b signaling involves c-Src (Homo sapiens)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1,3-di-(9Z-octadecenoyl)-glycerol


name: Myosin phosphatase dephosphorylates PLK1 (Drosophila melanogaster)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Sus scrofa)


name: GUCY2C trimer binds GUCA2A,B (Sus scrofa)


name: (S)-2,3-epoxysqualene + H2O => lupan-3beta,20-diol


name: ARFRP1 recruits ARL1 to the TGN (Sus scrofa)


name: IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Bos taurus)


name: diacetylchitobiose-6'-phosphate + H2O => acetate + N'-monoacetylchitobiose-6'-phosphate


name: 5-O-(L-seryl)-dTMP in DNA + H(+) = 5-aminoethoxy-methyl-dUMP in DNA + CO2


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-[(5Z,8Z,11Z,14Z)-eicosatetraenoylamino]ethyl (9Z)-octadecenoate


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: SET1 complex trimethylates H3K4 at the MYC gene (Bos taurus)


name: adenosine 3',5'-bisphosphate + H(+) + holo-[ACP] => apo-[ACP] + CoA


name: [thioredoxin]-disulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 6 H(+) + 2 hydrogen sulfide + 2 sulfite => 4 H2O + O2 + 4 sulfur


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Schizosaccharomyces pombe)


name: cytidine(61) in tRNA(Asp) + S-adenosyl-L-methionine <=> 5-methylcytidine(61) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose <=> dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H2O


name: Transphosphorylation of JAK1 (Gallus gallus)


name: COQ2 ligates all-E-10PrP2 to PHB (Saccharomyces cerevisiae)


name: ATP + N(1)-(3,4-dihydroxybenzoyl)-N(8)-citryl-spermidine + spermidine => AMP + diphosphate + H(+) + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine)


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Mus musculus)


name: Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Rattus norvegicus)


name: 3-oxohexadecanoyl-CoA + H(+) + NADPH => (3R)-hydroxyhexadecanoyl-CoA + NADP(+)


name: ergothioneine(out) + Na(+)(out) => ergothioneine(in) + Na(+)(in)


name: Intrinsic nucleotide exchange on RAS (Gallus gallus)


name: 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] => 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: a long-chain fatty acid + ATP + H(+) <=> a long-chain fatty acyl-AMP + diphosphate


name: "Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)"


name: PAK binds RAC and bPIX (Drosophila melanogaster)


name: IL4I1:FAD oxidises L-Phe to kPPV (Rattus norvegicus)


name: CoA + H(+) + N-docosanoylsphinganine => docosanoyl-CoA + sphinganine


name: butanal + H(+) + NADH + NH4(+) => butylamine + H2O + NAD(+)


name: a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: MAP1LC3B binds KEAP1 and SQSTM1 (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine <=> CoA + H(+) + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Sus scrofa)


name: Activated MET binds RANBP9 and SOS1 (Xenopus tropicalis)


name: MOBP gene expression is inhibited by MECP2 (Homo sapiens)


name: Transfer of Ub from E2 to substrate and release of E2 (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA <=> 3-oxochol-4,6-dien-24-oyl-CoA + H2O


name: Dissociation of phosphorylated PLC-gamma 1 from p-EGFRvIII mutant (Homo sapiens)


name: KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Caenorhabditis elegans)


name: Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate (Homo sapiens)


name: ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Rattus norvegicus)


name: DHODH:FMN binds DHODH inhibitors (Homo sapiens)


name: arginine + H2O => ornithine + urea [ARG1] (Canis familiaris)


name: Formation of the MLL1 complex (Drosophila melanogaster)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: SLC25A18,22 import L-Glu, H+ (Homo sapiens)


name: BHLHE22 recruits PRDM8 to intron 1 of CDH11 gene (Homo sapiens)


name: BRD7 promotes EP300-mediated acetylation of TP53 (Canis familiaris)


name: CHRNA9:CHRNA10 binds acetylcholine (Homo sapiens)


name: 3beta-hydroxy-5alpha-pregnane-20-one + NAD(+) <=> 5alpha-pregnane-3,20-dione + H(+) + NADH


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Saccharomyces cerevisiae)


name: CO2 + H(+) + succinate + validamycin B => 2-oxoglutarate + O2 + validamycin A


name: NOTCH1 PEST domain mutants bind JAG2 (Homo sapiens)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Plasmodium falciparum)


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Homo sapiens)


name: 3,4-dihydroxybenzoate + H2O + NADP(+) => 4-hydroxybenzoate + H(+) + NADPH + O2


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Homo sapiens)


name: NFE2L2 binds CREBBP,EP300 (Xenopus tropicalis)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Sus scrofa)


name: guanosine(26)/guanosine(27) in tRNA + 4 S-adenosyl-L-methionine => 4 H(+) + N(2)-dimethylguanosine(26)/N(2)-dimethylguanosine(27) in tRNA + 4 S-adenosyl-L-homocysteine


name: H2O + plasmodiophorol A <=> plasmodiophorol C


name: ATP + H2O + phosphonate(out) <=> ADP + H(+) + phosphate + phosphonate(in)


name: H2O + UDP-4-dehydro-6-deoxy-alpha-D-glucose => UDP-alpha-D-glucose


name: 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-nonadioyl-sn-glycero-3-phosphocholine


name: M protein oligomerization (Homo sapiens)


name: lithocholate + NADP(+) => 3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: POLI incorporates dNMP opposite to damaged DNA base (Gallus gallus)


name: gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Rattus norvegicus)


name: MAF1 translocates to the nucleus (Mus musculus)


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Saccharomyces cerevisiae)


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)


name: 3,6-dichlorocatechol + O2 => (2E,4E)-2,5-dichloromuconate + H(+)


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Homo sapiens)


name: Recruitment of IRF7 to TRAF6 (Homo sapiens)


name: A4GNT transfers GlcNAc to core 2 mucins (Drosophila melanogaster)


name: Activation of IKK complex (Canis familiaris)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Mus musculus)


name: an inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + GDP + H(+)


name: protein serine/threonine/tyrosine kinase activity


name: ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA (Danio rerio)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + phosphate => 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O


name: SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Bos taurus)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Bos taurus)


name: RHOD binds effectors at the endosome membrane (Mus musculus)


name: L-lysine + 2 S-adenosyl-L-methionine <=> 2 H(+) + N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine


name: Exocytosis of azurophil granule lumen proteins (Plasmodium falciparum)


name: PPARG:RXRA heterodimer binds to PPARG corepressors (Homo sapiens)


name: H(+) + ilicicolin A + NADPH + O2 = H2O + ilicicolin A epoxide + NADP(+)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP + CoA


name: dodecanoyl-CoA + H(+) + malonyl-CoA <=> 3-oxotetradecanoyl-CoA + CO2 + CoA


name: 2-oxoglutarate + N(6)-methyl-L-lysyl-[protein] + O2 <=> CO2 + formaldehyde + L-lysyl-[protein] + succinate


name: 2-oxoglutarate + a 1,N(2)-etheno-2'-deoxyguanosine in single-stranded DNA + H2O + O2 => a 2'-deoxyguanosine in single-stranded DNA + CO2 + glyoxal + succinate


name: YWHAE dimer binds phosphorylated DENND1 proteins (Drosophila melanogaster)


name: Metallochaperone inserts Cu2+ into MT-CO1 (Canis familiaris)


name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate (Homo sapiens)


name: E2F6 forms the PRC1L4 complex (Gallus gallus)


name: citrate(in) + phosphoenolpyruvate(out) => citrate(out) + phosphoenolpyruvate(in)


name: a disubstituted aliphatic (S)-hydroxynitrile <=> a ketone + hydrogen cyanide


name: 9alpha-copalyl diphosphate <=> diphosphate + stemar-13-ene


name: PSGs bind proteoglycans and TGF-beta1 (Sus scrofa)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Dictyostelium discoideum)


name: dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] = CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: 3-formylthiophene + hydrogen cyanide => (2S)-2-hydroxy-2-(thiophen-3-yl)acetonitrile


name: SLC35D2 exchanges UDP-D-glucose for UMP (Bos taurus)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = an isogloboside iGb3Cer (d18:1(4E)) + H(+) + UDP


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Drosophila melanogaster)


name: Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Canis familiaris)


name: Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Rattus norvegicus)


name: CX3 complex binds D-loop structures (Rattus norvegicus)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Drosophila melanogaster)


name: HRH4 binds Hist (Caenorhabditis elegans)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Gallus gallus)


name: H2O + O2 + sarcosine = formaldehyde + glycine + H2O2


name: (7Z,10Z,13Z)-hexadecatrienoate phytyl ester + CoA => (7Z,10Z,13Z)-hexadecatrienoyl-CoA + phytol


name: cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Canis familiaris)


name: 27-O-demethylrifamycin SV + S-adenosyl-L-methionine => H(+) + rifamycin SV + S-adenosyl-L-homocysteine


name: DHI and DHICA polymerize forming eumelanin (Bos taurus)


name: 2-oxoglutarate + L-aspartyl-[protein] + O2 <=> 3-hydroxy-L-aspartyl-[protein] + CO2 + succinate


name: Formation of collagen fibrils (Danio rerio)


name: 3-oxohexadecanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyhexadecanoyl-[ACP] + NADP(+)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Bos taurus)


name: (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase]


name: PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Sus scrofa)


name: GALNT3 transfers GalNAc to FGF23 (Drosophila melanogaster)


name: α1-antagonists bind ADRA1A,B,D (Danio rerio)


name: Release of GNB5:RGS dimers from CCT/TRiC (Drosophila melanogaster)


name: abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase]


name: Addition of nucleotides leads to transcript elongation (Drosophila melanogaster)


name: (2R,5R)-isomenthone + NADP(+) = (R)-pulegone + H(+) + NADPH


name: MFAP2, MFAP5 bind microfibrils (Homo sapiens)


name: SHC1 binds to the phosphorylated EGF receptor:ligand complex (Mus musculus)


name: all-trans-8'-apo-beta-carotenal + O2 => (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + all-trans-retinal


name: p38MAPK phosphorylates MSK1 (Drosophila melanogaster)


name: a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O <=> a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + sulfate


name: an N(6)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine => an adenosine in mRNA + S-adenosyl-L-methionine


name: (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate => 3-chloro-cis,cis-muconate + H(+)


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Rattus norvegicus)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Mus musculus)


name: p-PKR dimer phosphorylates PTPN2 (Gallus gallus)


name: L-ribulose 5-phosphate <=> D-xylulose 5-phosphate


name: EDNRA, EDNRB bind non-selective ERAs (Bos taurus)


name: 2 glutathione + tert-butyl hydroperoxide => glutathione disulfide + H2O + tert-butanol


name: Assembly of telomerase RNP (Gallus gallus)


name: a globoside MSGG (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a globoside DSGG (d18:1(4E)) + CMP + H(+)


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Homo sapiens)


name: Formation of Cyclin B:Cdc2 complexes (Mus musculus)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H(+) + UDP => beta-D-glucosylceramide + UDP-alpha-D-galactose


name: (E)-4-coumaroyl-CoA + H2O => (R)-3-(4-hydroxyphenyl)lactoyl-CoA


name: O2 + psoralen + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + xanthotoxol


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Canis familiaris)


name: Phosphorylation of PKC theta (Bos taurus)


name: carbonyl sulfide + NH4(+) => 2 H(+) + H2O + thiocyanate


name: TFAP2A homodimer binds CDKN1A (p21) gene (Homo sapiens)


name: a medium-chain 3-oxoacyl-CoA + CoA => a medium-chain fatty acyl-CoA + acetyl-CoA


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Drosophila melanogaster)


name: ATP + H2O + sulfate(out) = ADP + H(+) + phosphate + sulfate(in)


name: [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + H(+) + NADPH + O2 <=> [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B + H2O + NADP(+)


name: H(+) + L-2-aminoadipate + NADPH => 2 H2O + L-1-piperideine-6-carboxylate + NADP(+)


name: 2 glutathione + NADP(+) => glutathione disulfide + H(+) + NADPH


name: RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Mus musculus)


name: Factor I inactivates plasma Factor H-bound C3b (Homo sapiens)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Caenorhabditis elegans)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Xenopus tropicalis)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Drosophila melanogaster)


name: Proteasome-mediated degradation of PolyUb-FBXL7 (Mus musculus)


name: AKT phosphorylates CREB1 (Rattus norvegicus)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: 3-oxo-3-ureidopropanoate + H2O = H(+) + malonate + urea


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Canis familiaris)


name: 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP => 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+)


name: 3'-phosphoadenylyl sulfate + glycocholate = adenosine 3',5'-bisphosphate + glycocholate 7-sulfate + H(+)


name: 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + H(+) + phosphate => ATP + geranoyl-CoA + hydrogencarbonate


name: Interaction of particulate antigens with dendritic cell receptors (Mus musculus)


name: L-threitol + NAD(+) = H(+) + L-erythrulose + NADH


name: RAPGEF1 binds CRK,CRKL (Canis familiaris)


name: cyanidin 3-O-beta-D-galactoside + UDP-alpha-D-xylose <=> cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside] + H(+) + UDP


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Canis familiaris)


name: gamma-terpinene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + thymol


name: "With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen"


name: an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O => an N-acyl-(4R)-4-hydroxysphinganine + H(+) + mannosyldiinositol-1-phosphate


name: Degradation of ubiquitinated SKI/SKIL (Rattus norvegicus)


name: 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2-succinylamino-6-oxoheptanedioate + L-glutamate


name: (Z)-N-(sulfonatooxy)prop-2-enimidothioate <=> but-3-enenitrile + sulfate + sulfur


name: SENP1,2,5 proteolytically process SUMO1 (Homo sapiens)


name: Cis-Heterodimerization of nephrin and KIRREL (Caenorhabditis elegans)


name: SHP2 dephosphorylates Tyr 992 on EGFR (Xenopus tropicalis)


name: Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)


name: L-pipecolate(out) + Na(+)(out) => L-pipecolate(in) + Na(+)(in)


name: H2O(out) + nitrite(out) + ubiquinone-8(in) => nitrate(out) + ubiquinol-8(in)


name: soyasapogenol B 3-O-beta-D-glucuronate + UDP-alpha-D-galactose = H(+) + soyasaponin III + UDP


name: "soyasapogenol B glucuronide galactosyltransferase"


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Gallus gallus)


name: Connexin 62 mediated neuronal gap junction communication (Sus scrofa)


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Gallus gallus)


name: RAF phosphorylates MAP2K dimer (Mus musculus)


name: cytidine 5'-diphosphoramidate + H(+) + L-glutamate => H2O + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine


name: H(+)(out) + minocycline(in) = H(+)(in) + minocycline(out)


name: gramine + 2 H(+) + 2 S-adenosyl-L-homocysteine => 3-(aminomethyl)indole + 2 S-adenosyl-L-methionine


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Danio rerio)


name: FLT3 mutants phosphorylate GAB2 (Homo sapiens)


name: 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + FMN + H(+) + H2O => 4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + FMNH2 + O2


name: a dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] => 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a dolichyl phosphate + H(+)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Bos taurus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + H2O


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Canis familiaris)


name: H(+) + holo-[ACP] + N(6)-[(9Z)-hexadecenoyl]-L-lysyl-[protein] => (9Z)-hexadecenoyl-[ACP] + L-lysyl-[protein]


name: chloride + FADH2 + melleolide F + O2 = 6'-chloromelleolide F + FAD + H(+) + 2 H2O


name: 1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: KSRP binds AU-rich element in 3' UTR of mRNA (Bos taurus)


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Schizosaccharomyces pombe)


name: dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine <=> dTDP-alpha-D-forosamine + H(+) + S-adenosyl-L-homocysteine


name: SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Mus musculus)


name: (3S)-hydroxyoctanoyl-CoA = (2E)-octenoyl-CoA + H2O


name: 4-hydroxy-6-nonadecylpyran-2-one + 2 CO2 + 3 CoA => eicosanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: ALDH7A1 oxidises BETALD to BET (Sus scrofa)


name: (1R,4R)-dihydrocarvone + A <=> (R)-carvone + AH2


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Bos taurus)


name: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH


name: Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)


name: LARP1 binds SARS-CoV-2 RNA (Homo sapiens)


name: ABCAs mediate lipid efflux (Dictyostelium discoideum)


name: CO2 + Delta(9)-tetrahydrocannabinol => Delta(9)-tetrahydrocannabinolate + H(+)


name: Ral-GDS binds to Ras-GTP (Canis familiaris)


name: RFC dissociates after sliding clamp formation (Sus scrofa)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Bos taurus)


name: a 1-acyl-sn-glycerol + a fatty acid + H(+) => a 1,3-diacylglycerol + H2O


name: paromamine + UDP-alpha-D-glucose = 3''-deamino-3''-hydroxykanamycin C + H(+) + UDP


name: AGT(34-41) binds to AGTR2 (Mus musculus)


name: dibenzothiophene 5,5-dioxide + FMNH2 + NADH + O2 <=> 2'-hydroxybiphenyl-2-sulfinate + FMN + H(+) + H2O + NAD(+)


name: ALOX5 oxidises 15S-HpETE to LXA4/B4 (Bos taurus)


name: SUMOylation of PML with SUMO3 (Sus scrofa)


name: 3 S-adenosyl-L-methionine <=> 3 H(+) + nicotianamine + 3 S-methyl-5'-thioadenosine


name: ATP + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine = 6-O-phospho-N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine + ADP + H(+)


name: GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH


name: di-trans,octa-cis-undecaprenyl diphosphate + H2O <=> di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate


name: (9Z)-hexadecenoyl-CoA + 3-oxosphinganine <=> CoA + H(+) + N-(9Z-hexadecenoyl)-3-oxosphinganine


name: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity


name: EPS15 and HGS bind ubiquitinated MET (Sus scrofa)


name: [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + ADP => [amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ATP


name: RHOB GAPs stimulate RHOB GTPase activity (Rattus norvegicus)


name: a long-chain fatty acid + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> a long-chain fatty acyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: Oxidative damage to the AP site (Caenorhabditis elegans)


name: O2 + reduced [NADPH--hemoprotein reductase] + ursodeoxycholate => beta-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Danio rerio)


name: CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Homo sapiens)


name: alpha-D-mannose 1-phosphate + GMP + 2 H(+) => GDP-alpha-D-mannose + H2O


name: ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) + phosphate


name: Exocytosis of ficolin-rich granule lumen proteins (Canis familiaris)


name: TMEM55B translocates to the nucleus (Drosophila melanogaster)


name: phosphoadenylyl-sulfate reductase (thioredoxin) activity


name: DRD2 antagonist drugs bind to DRD2 (Homo sapiens)


name: Fe3+ dissociates from holoTF:TFRC dimer (Homo sapiens)


name: EPH:EFN dimers tetramerise (Mus musculus)


name: H(+) + malonyl-[ACP] + tetradecanoyl-[ACP] <=> 3-oxohexadecanoyl-[ACP] + CO2 + holo-[ACP]


name: endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters


name: "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters"


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 3-hydroxy-L-phenylalanine => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Drosophila melanogaster)


name: PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Sus scrofa)


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Bos taurus)


name: a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-galactose => a 1,2-diacyl-3-O-[alpha-D-galactopyranosyl-(1->2)-alpha-D-glucopyranosyl]-sn-glycerol + H(+) + UDP


name: GOT2 transaminates OA and L-Glu (Xenopus tropicalis)


name: H2O + sucrose 6(F)-phosphate => beta-D-fructose + beta-D-glucose 6-phosphate


name: Connexin oligomerization in endoplasmic reticulum membrane (Homo sapiens)


name: acetyl-CoA + CO2 + NADPH => 3-oxopropanoate + CoA + NADP(+)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Gallus gallus)


name: MAP3K8 is phosphorylated (Xenopus tropicalis)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Dictyostelium discoideum)


name: dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2 H(+) + H2O + oleanolate + oxidized [NADPH--hemoprotein reductase] => O2 + oleanolic aldehyde + reduced [NADPH--hemoprotein reductase]


name: LRRC16A binds F-actin capping protein (Canis familiaris)


name: PI3K synthesizes PIP3 downstream of ALK (Xenopus tropicalis)


name: (25R)-3-oxocholest-4-en-26-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => (25R)-3-oxocholest-4-en-26-al + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Dictyostelium discoideum)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Xenopus tropicalis)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate <=> 1D-myo-inositol 1,3,4,5-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate


name: 4-methylumbelliferone sulfate(in) + ATP + H2O <=> 4-methylumbelliferone sulfate(out) + ADP + H(+) + phosphate


name: SLC25A11 exchanges 2-OG and MAL (Caenorhabditis elegans)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NAD(+) <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH


name: Activated protein C:PROCR binds F2R (Gallus gallus)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine <=> 1-O-acyl-N-(acetyl)-sphing-4-enine + 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: L-cystine(in) + L-leucine(out) => L-cystine(out) + L-leucine(in)


name: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Rattus norvegicus)


name: a ketone + H(+) + H2O2 + nitrite => a secondary nitroalkane + H2O + O2


name: L-histidine(in) + Na(+)(in) => L-histidine(out) + Na(+)(out)


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Rattus norvegicus)


name: [protein]-C-terminal-L-glutamate + NH4(+) => [protein]-C-terminal-L-glutamine + H2O


name: adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Dictyostelium discoideum)


name: a quinone + H(+) + NADPH = a quinol + NADP(+)


name: Tachykinin receptor 1 (NK1) binds to substance P (Canis familiaris)


name: 2-furoyl-CoA + A + H2O = 5-hydroxy-2-furoyl-CoA + AH2 + H(+)


name: 26-hydroxylanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => lanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: RLBP1 binds atROL to form RLBP1:atROL (Danio rerio)


name: PTGIR binds PTGIR agonists (Drosophila melanogaster)


name: CCND1 recruits HDAC4 to RUNX3 (Mus musculus)


name: (2E,15Z)-tetracosadienoyl-CoA + H(+) + NADPH => (15Z)-tetracosenoyl-CoA + NADP(+)


name: ATP + H(+) + NADPH + propanoate <=> AMP + diphosphate + NADP(+) + propanal


name: NMT1/2 transfer MYS to GNAT1 (Mus musculus)


name: H2O + tetrathionate = H(+) + sulfate + sulfur + thiosulfate


name: LUM (lumican) binds integrin alpha2beta1 (Canis familiaris)


name: Elongation of pre-rRNA transcript (Sus scrofa)


name: (11Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: H2O + N-acetyl-alpha-D-glucosamine + NAD(+) => 2 H(+) + N-acetyl-D-glucosaminate + NADH


name: (4R)-hydroxysphing-(8Z)-enine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphing-(8Z)-enine


name: p-STAT5 dissociates from activator:STAT5 complex (Homo sapiens)


name: [protein]-with a C-terminal TM segment(in) + ADP + H(+) + phosphate => [protein]-with a C-terminal TM segment(out) + ATP + H2O


name: L-leucyl-tRNA(Leu) + L-phenylalanyl-tRNA(Phe) => cyclo(L-phenylalanyl-L-leucyl) + H(+) + tRNA(Leu) + tRNA(Phe)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: acetaldehyde + H(+) + NADH + NH4(+) => ethylamine + H2O + NAD(+)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Danio rerio)


name: 3-oxochol-4-en-24-oyl-CoA + H(+) + NADH => 3-oxocholan-24-oyl-CoA + NAD(+)


name: Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 (Homo sapiens)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Homo sapiens)


name: L-threonyl-[protein] + UTP <=> diphosphate + uridylyl-L-threonyl-[protein]


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Dictyostelium discoideum)


name: p-S MAPK6 phosphorylates NCOA3 (Gallus gallus)


name: ATP + gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate = ADP + H(+) + L-glutamyl-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + phosphate


name: 1-O-alkyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + phosphate => 1-O-alkyl-2-acyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) + H2O


name: USP11 deubiquitinates NFKBIA (Sus scrofa)


name: GBF1 stimulates nucleotide exchange on ARF4 (Plasmodium falciparum)


name: (9Z)-tetradecenoyl-CoA + H2O <=> (9Z)-tetradecenoate + CoA + H(+)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Canis familiaris)


name: (2S)-hesperetin + UDP-alpha-D-glucose = (2S)-hesperetin 7-O-beta-D-glucoside + H(+) + UDP


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Xenopus tropicalis)


name: ATP + dodecanoate(out) + H2O <=> ADP + dodecanoate(in) + H(+) + phosphate


name: nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA (Homo sapiens)


name: GDIs block activation of RHOA (Mus musculus)


name: H2O + trithionate <=> H(+) + sulfate + thiosulfate


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose => a neolactoside V(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Drosophila melanogaster)


name: 3-hydroxytetradecanoyl-CoA + 2 H(+) + 2 malonyl-CoA => 4-hydroxy-6-(2-hydroxytridecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: Oligomerization of TRAF6 (Canis familiaris)


name: 9-octadecanoyloxy-octadecanoate + H2O <=> 9-hydroxy-octadecanoate + H(+) + octadecanoate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol <=> a 1-acyl-sn-glycero-3-phosphocholine + a 2,3-diacyl-sn-glycerol


name: Electron transfer from reduced cytochrome c to molecular oxygen (Rattus norvegicus)


name: acetyl-CoA + glyoxylate => (S)-malyl-CoA


name: a 5-hydroxymethyl-2'-deoxycytidine in DNA + CO2 + succinate => 2-oxoglutarate + a 5-methyl-2'-deoxycytidine in DNA + O2


name: Synthesis of dolichyl-phosphate-glucose (Schizosaccharomyces pombe)


name: H2O + NAD(+) + serinol => dihydroxyacetone + H(+) + NADH + NH4(+)


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Sus scrofa)


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Gallus gallus)


name: a 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA => (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphate


name: SIRT1 deacetylates HINT1 dimer (Bos taurus)


name: gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Gallus gallus)


name: MRN bound to shortened telomeres activates ATM (Mus musculus)


name: (11R)-dihydroartemisinate + 2 H(+) + NADH => (11R)-dihydroartemisinic aldehyde + H2O + NAD(+)


name: ITPA hydrolyses XTP to XMP (Schizosaccharomyces pombe)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-alanine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-alanine


name: H(+)(in) + L-phenylalanine(in) = H(+)(out) + L-phenylalanine(out)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Homo sapiens)


name: cholesterol + H(+) + NADPH + O2 = 7-dehydrocholesterol + 2 H2O + NADP(+)


name: H(+) + N,N-dihydroxy-L-tyrosine => (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Homo sapiens)


name: NEIL1 translocates to the nucleus (Mus musculus)


name: Removal of remaining Flap (Saccharomyces cerevisiae)


name: Autocatalytic activation of MMP3 (Caenorhabditis elegans)


name: Caspase-8 and FLIP(L) processing at DISC (Homo sapiens)


name: sphinganine + stearyl-CoA => dihydroceramide + CoASH (Gallus gallus)


name: mandelonitrile + vicianose => (R)-vicianin + H2O


name: dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH


name: N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Drosophila melanogaster)


name: 3 Na(+)(out) + succinate(out) <=> 3 Na(+)(in) + succinate(in)


name: LTBP1, LTBP3 bind TGF-Beta (Gallus gallus)


name: [protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide => [protein]-dithiol + 2 AH2 + H(+) + sulfite


name: a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose 6-phosphate + H(+)


name: 6 (S)-methylmalonyl-CoA + 12 H(+) + malonyl-CoA + 5 NADPH => 7 CO2 + 7 CoA + 2 H2O + 5 NADP(+) + narbonolide


name: 3-hydroxy-4-methyl-D-kynurenine + H(+) + S-adenosyl-L-homocysteine => 3-hydroxy-D-kynurenine + S-adenosyl-L-methionine


name: Frataxin transfers Fe2+ to ACO2 (Caenorhabditis elegans)


name: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + H2O => 1D-myo-inositol 1,4,5-trisphosphate + phosphate


name: mechanosensitive voltage-gated sodium channel activity


name: STON2 binds SYT proteins (Rattus norvegicus)


name: GRB2:SOS1 complex binds to the active receptor (Homo sapiens)


name: pyrimidine nucleotide transmembrane transporter activity


name: hydrolase activity, acting on acid anhydrides


name: 1-carboxybiuret + H2O => NH4(+) + urea-1,3-dicarboxylate


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Rattus norvegicus)


name: Interleukin-27 binds Interleukin-27 receptor (Bos taurus)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Canis familiaris)


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Gallus gallus)


name: ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA (Homo sapiens)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Danio rerio)


name: AKT1 phosphorylates NOTCH4 (Homo sapiens)


name: Syndecans 1, 2 & 4 bind VTN (Canis familiaris)


name: L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Sus scrofa)


name: NMT1/2 transfer MYS to GNAT1 (Canis familiaris)


name: (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H2O => (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA


name: H(+) + H2O + N-isopropylammelide = cyanurate + isopropylamine


name: "phosphogluconate dehydrogenase [NAD(P)(+)-dependent, decarboxylating]"


name: CYP3A7 can 6beta-hydroxylate testosterone (Xenopus tropicalis)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Sus scrofa)


name: dTDP-alpha-D-fucose + NADP(+) <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH


name: 6-hydroxynicotinate + 2 H(+) + NADH + O2 <=> 2,5-dihydroxypyridine + CO2 + H2O + NAD(+)


name: HNF1A-dependent synthesis of FOXA3 (Homo sapiens)


name: The 60S subunit joins the translation initiation complex  (Rattus norvegicus)


name: nicotinamide mononucleotide transmembrane transporter activity


name: GOPC promotes translocation of CFTR to lysosomes (Mus musculus)


name: 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => 1-O-alkyl-2,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: 2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol


name: D-serine(out) + L-alanine(in) = D-serine(in) + L-alanine(out)


name: NICD1 displaces co-repressor complex from RBPJ (CSL) (Homo sapiens)


name: hexadecanoate + O2 <=> (2R)-2-hydroperoxyhexadecanoate


name: NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP (Canis familiaris)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Drosophila melanogaster)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] <=> 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin]


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: an alkyl thiol + NH4(+) + pyruvate => an S-alkyl-L-cysteine + H2O


name: 2 acetyl-CoA + 5 H(+) + 6 malonyl-CoA = 6 CO2 + 8 CoA + H2O + o-orsellinate depside


name: diphosphate + pestalodiol => dimethylallyl diphosphate + siccayne


name: 3'-phosphoadenylyl sulfate + firefly D-luciferin <=> adenosine 3',5'-bisphosphate + firefly D-sulfoluciferin + H(+)


name: H2O + sn-glycero-3-phosphoethanolamine <=> ethanolamine + H(+) + sn-glycerol 3-phosphate


name: IL3 stimulation induces Vav binding to Tec kinase (Bos taurus)


name: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Canis familiaris)


name: Integrin alpha5beta1 binds FN1 dimer (Caenorhabditis elegans)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Drosophila melanogaster)


name: (1S,2S,4S)-dihydrocarveol + NAD(+) => (1S,4S)-dihydrocarvone + H(+) + NADH


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: GUCA binds Ca2+ to form GUCA:Ca2+ (Gallus gallus)


name: 1-tetradecanoyl-sn-glycerol 3-phosphate + CoA => sn-glycerol 3-phosphate + tetradecanoyl-CoA


name: (1R,4R)-camphor + H(+) + NADPH + O2 <=> (+)-6-exo-hydroxycamphor + H2O + NADP(+)


name: Recruitment of DNA2 endonuclease to the C strand (Sus scrofa)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Caenorhabditis elegans)


name: NICD2 binds RBPJ and MAML in the nucleus (Gallus gallus)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Rattus norvegicus)


name: (9Z)-tetradecenoate + ATP + CoA = (9Z)-tetradecenoyl-CoA + AMP + diphosphate


name: EGFR non-clathrin mediated endocytosis (Drosophila melanogaster)


name: 5alpha-campestan-3-one + NADP(+) = campest-4-en-3-one + H(+) + NADPH


name: 3beta-hydroxy-16alpha,17alpha-epoxypregnenolone 3-beta-D-glucoside + H(+) + UDP => 3beta-hydroxy-16alpha,17alpha-epoxypregnenolone + UDP-alpha-D-glucose


name: a dolichyl phosphate + D-mannose + H(+) => a dolichyl beta-D-mannosyl phosphate + H2O


name: Caspase-mediated cleavage of Desmoglein 3 (Rattus norvegicus)


name: a sphingoid base + hexadecanoyl-CoA <=> an N-hexadecanoyl-sphingoid base + CoA + H(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + solavetivol <=> H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + solavetivone


name: H2O + N(5)-[1(S)-1-carboxyethyl]-L-ornithine + NADP(+) <=> H(+) + L-ornithine + NADPH + pyruvate


name: Homodimerization  of DFF40 (Gallus gallus)


name: PIAS3 SUMOylates MITF with SUMO1 (Bos taurus)


name: NEU3 hydrolyzes Neu5Ac from glycoconjugates (Gallus gallus)


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Drosophila melanogaster)


name: beta-L-galactose 1-phosphate + GDP + H(+) => GDP-beta-L-galactose + phosphate


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Homo sapiens)


name: (2E)-thiogeraniol + 5-methylaminomethyl-2-selenouridine(34) in tRNA + diphosphate + phosphate => (2E)-geranyl diphosphate + 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + H2O + selenophosphate


name: 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol => 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)


name: Full activation of MMP1 (Drosophila melanogaster)


name: 3-methylbutanoyl-CoA + H(+) + malonyl-[ACP] => 5-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA


name: HEY1 gene expression is stimulated by NOTCH4 (Homo sapiens)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA


name: ATP7A transports cytosolic Cu2+ to extracellular region (Homo sapiens)


name: Activation of RAC1 by VAV (Gallus gallus)


name: RPS6KA1-dependent phosphorylation of MITF-M (Xenopus tropicalis)


name: Vamp2 associated secretory vesicle to plasma membrane transport (Dictyostelium discoideum)


name: RET binds GFRA1,GFRA3 (Rattus norvegicus)


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Xenopus tropicalis)


name: an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH => a (2S,3S)-flavan-3-ol + 2 NADP(+)


name: D-lactate dehydrogenase (quinone) activity


name: rhamnetin + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: 2 AH2 + CO2 + hydrogen cyanide => 2 A + glycine


name: a jasmonyl-L-amino acid + H2O <=> a jasmonate + an L-alpha-amino acid


name: KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphate(in) = a 1,2-diacyl-sn-glycero-3-phosphate(out)


name: gamma-secretase cleaves EPHB2 (Xenopus tropicalis)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) <=> 3-(4-hydroxyphenyl)pyruvate + H(+) + NADH


name: PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL3 complex (Mus musculus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerone 3-phosphate + hexadecanoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoylglycerone 3-phosphate


name: dihydrocarveol + NAD(+) <=> dihydrocarvone + H(+) + NADH


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Rattus norvegicus)


name: S-adenosyl-L-methionine transmembrane transporter activity


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Homo sapiens)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Sus scrofa)


name: (9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = 17-hydroxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: dithioerythritol + thiosulfate = cis-1,2-dithiane-4,5-diol + 2 H(+) + hydrogen sulfide + sulfite


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Rattus norvegicus)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphate + H2O => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+)


name: Autocatalytic phosphorylation of FGFR3b (Mus musculus)


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O => (9Z)-octadecenoate + 1-hexadecanoyl-3-octadecanoyl-sn-glycerol + H(+)


name: IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Mus musculus)


name: Autophagosome maturation (Plasmodium falciparum)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Dictyostelium discoideum)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine


name: (2Z,6Z)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate


name: CoA + phenylacetyl-AMP => AMP + H(+) + phenylacetyl-CoA


name: Recruitment of IRF to activated TBK1/IKK epsilon (Gallus gallus)


name: PDE5A dimer binds PDE5A inhibitors (Sus scrofa)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Homo sapiens)


name: AH2 + 2 ATP + H2O + hydroxylamine => A + 2 ADP + H(+) + NH4(+) + 2 phosphate


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Caenorhabditis elegans)


name: ERBB2 KD mutants bind TKIs (Homo sapiens)


name: 2 Fe(2+) + 4 H2O + O2 = 6 H(+) + H2O2 + 2 iron(III) oxide-hydroxide


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Mus musculus)


name: carminate + 2 H(+) + UDP => kermesate + UDP-alpha-D-glucose


name: H2O + N(6)-methyl-dATP <=> diphosphate + H(+) + N(6)-methyl-dAMP


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Drosophila melanogaster)


name: dehydroepiandrosterone 3-sulfate + O2 + reduced [NADPH--hemoprotein reductase] => 16alpha-hydroxydehydroepiandrosterone 3-sulfate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glycyrrhetinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => glycyrrhetaldehyde + O2 + reduced [NADPH--hemoprotein reductase]


name: 17alpha-hydroxyprogesterone + NADPH + O2 => acetate + androst-4-ene-3,17-dione + H2O + NADP(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol


name: alpha-L-arabinopyanose + NADP(+) => H(+) + L-arabinono-1,4-lactone + NADPH


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-(2S,3R,9R)-pristinol + diphosphate


name: P2Y4 receptor can bind to UTP (Homo sapiens)


name: DHCR24 reduces LAN to 24,25-dhLAN (Canis familiaris)


name: CoA + O-3-oxobutanoyl-(R)-carnitine => (R)-carnitine + acetoacetyl-CoA


name: GNRHR binds GNRHR peptide antagonists (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: (indol-3-yl)acetyl-AMP + CoA => (indol-3-yl)acetyl-CoA + AMP + H(+)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Drosophila melanogaster)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Bos taurus)


name: Proteasome mediated degradation of COP1 (Rattus norvegicus)


name: ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate


name: p-Y705-STAT3 binds p-Y693-STAT4 (Canis familiaris)


name: 3-oxoeicosanoyl-CoA + H(+) + NADPH = (3R)-hydroxyeicosanoyl-CoA + NADP(+)


name: Protein Kinase B (AKT) phosphorylates KSRP (Drosophila melanogaster)


name: Activation of GIRK/Kir3 Channels (Sus scrofa)


name: AMOT proteins bind WWTR1 (TAZ) (Mus musculus)


name: maleate(in) + sulfate(out) => maleate(out) + sulfate(in)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E,19Z)-docosahexaenoate


name: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate


name: POLD,POLE binds deISGylated PCNA after TLS (Caenorhabditis elegans)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Caenorhabditis elegans)


name: O-GlcNAcylation of RIPK3 (TLR4 signaling) (Mus musculus)


name: adenosylcob(III)alamin + apo-[corrinoid adenosyltransferase] + triphosphate => ATP + cob(I)alamin-[corrinoid adenosyltransferase]


name: HOXB2 chromatin is activated (Homo sapiens)


name: Nitrogen dioxide is reduced to NO by F420 (Homo sapiens)


name: ecdysone + phosphate => ecdysone 22-phosphate + H2O


name: (7Z,10Z,13Z,16Z)-docosatetraenoate + glycerol + H(+) => 1-(7Z,10Z,13Z,16Z-docosatetraenoyl)-glycerol + H2O


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Dictyostelium discoideum)


name: apigenin + UDP-alpha-D-glucose <=> H(+) + isovitexin + UDP


name: GST dimers conjugate GSH with cytosolic substrates (Danio rerio)


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Homo sapiens)


name: A + ADP + 2 Co(I)-[methylamine-specific corrinoid protein] + 3 H(+) + phosphate => AH2 + ATP + 2 Co(II)-[methylamine-specific corrinoid protein] + H2O


name: 3,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: PAKs autophosphorylate (Drosophila melanogaster)


name: fraxetin + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sideretin (reduced form)


name: SUMOylation of TDG with SUMO1 (Rattus norvegicus)


name: CO binds to free ferrohemoglobin (Bos taurus)


name: CXXC1 and WDR82 bind SET1A complex (Drosophila melanogaster)


name: (1R,4S)-isodihydrocarvone + A => (S)-carvone + AH2


name: PTK2 autophosphorylates (Rattus norvegicus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Bos taurus)


name: fumarate(in) + 2 H(+)(in) = fumarate(out) + 2 H(+)(out)


name: Ubiquitinated TP53 translocates to the cytosol (Danio rerio)


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Canis familiaris)


name: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an (omega-1)-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: butyrolactone II + dimethylallyl diphosphate <=> butyrolactone I + diphosphate


name: L-glutamate + N(2)-acetyl-L-ornithine => L-ornithine + N-acetyl-L-glutamate


name: PDE3A inhibitors bind PDE3A (Plasmodium falciparum)


name: an N-acyl-D-glutamate + H2O = a carboxylate + D-glutamate


name: 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-methionine = 3-methoxy,4-hydroxy-5-all-trans-polyprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 (Homo sapiens)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Canis familiaris)


name: Dephosphorylation of phospho-Cdh1 (Schizosaccharomyces pombe)


name: CHIT1 hydrolyses CHIT to 3xADGP (Mus musculus)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O = (17E)-cheilanthenediol


name: ESR-associated SRC autophosphorylates (Canis familiaris)


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Xenopus tropicalis)


name: ITSN1 exchanges GTP for GDP on CDC42, activating it (Homo sapiens)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate


name: "unsaturated chondroitin disaccharide hydrolase"


name: 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + H2O + NAD(+) => aurachin C + H(+) + NADH + O2


name: H2O + octanedioyl-CoA => CoA + H(+) + octanedioate


name: alpha-D-tagatopyranose 1-phosphate + ATP => ADP + D-tagatofuranose 1,6-bisphosphate + H(+)


name: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + H(+) + L-tyrosine methyl ester 4-sulfate


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Sus scrofa)


name: 5-formimidoyltetrahydrofolate + 2 H(+) <=> (6R)-5,10-methenyltetrahydrofolate + NH4(+)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine


name: 2-oxoglutarate + L-lysyl-[protein] + O2 = 4-hydroxy-L-lysyl-[protein] + CO2 + succinate


name: (2E,6E,10E)-geranylgeraniol + CTP => (2E,6E,10E)-geranylgeranyl phosphate + CDP + H(+)


name: (E)-ferulate + glycine => H2O + N-feruloylglycine


name: 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) = (+)-costunolide + H2O


name: H(+) + NADH + O2 + quinolin-2-ol => 5,6-dihydroquinoline-2,5,6-triol + NAD(+)


name: Formation of NR-NCOR Corepressor Complex (Rattus norvegicus)


name: Transhomodimerization of Nectin-like (Necl) proteins (Sus scrofa)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Sus scrofa)


name: ATP + H2O + sphing-4-enine(in) = ADP + H(+) + phosphate + sphing-4-enine(out)


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Bos taurus)


name: CoA + GTP + succinate <=> GDP + phosphate + succinyl-CoA


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Rattus norvegicus)


name: D-glutamate + D-glutamine <=> gamma-D-glutamyl-D-glutamate + NH4(+)


name: L-tryptophan(in) + Na(+)(in) <=> L-tryptophan(out) + Na(+)(out)


name: The ABCC family mediates organic anion transport (Sus scrofa)


name: ATP + CoA + malonate <=> AMP + diphosphate + malonyl-CoA


name: 2-dehydro-3-deoxy-L-fuconate + NAD(+) = 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH


name: Activated FGFR4 binds FRS3 (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-[(5Z,8Z,11Z,14Z)-eicosatetraenoylamino]ethyl (9Z)-octadecenoate


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Mus musculus)


name: L-galactono-1,4-lactone + O2 = H(+) + H2O2 + L-ascorbate


name: LONP1 degrades mitochondrial inner membrane proteins (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Schizosaccharomyces pombe)


name: 2'-deoxymugineate + 2-oxoglutarate + O2 => CO2 + mugineate + succinate


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Rattus norvegicus)


name: LONP1 binds mitochondrial matrix proteins (Drosophila melanogaster)


name: H2O + hexano-6-lactone + NADP(+) => cyclohexanone + H(+) + NADPH + O2


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Schizosaccharomyces pombe)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol => 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: A + H2O + N(6)-methyl-L-lysyl-[protein] <=> AH2 + formaldehyde + L-lysyl-[protein]


name: (S)-2,3-diaminopropanoate + oxalyl-CoA = CoA + N(3)-oxalyl-L-2,3-diaminopropanoate


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Saccharomyces cerevisiae)


name: H2O + protodioscin <=> 26-deglucoprotodioscin + D-glucose


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + O2 <=> (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Homo sapiens)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H2O => (3R)-hydroxy-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA


name: TCR binds microbial lipid-based antigen via CD1 (Mus musculus)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Schizosaccharomyces pombe)


name: (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) = 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: H(+) + malonyl-[ACP] + octanoyl-[ACP] => 3-oxodecanoyl-[ACP] + CO2 + holo-[ACP]


name: Transfer of NEDD8 to AcM-UBE2M (Dictyostelium discoideum)


name: pyridine + thiamine <=> 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine


name: ADP + H(+) + K(+)(out) + phosphate => ATP + H2O + K(+)(in)


name: cholesteryl (9Z-octadecenoate)(in) = cholesteryl (9Z-octadecenoate)(out)


name: (S)-muconolactone = cis,cis-muconate + H(+)


name: dUTP + H2O => dUMP + pyrophosphate (Homo sapiens)


name: H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2


name: HDAC3 containing complexes deacetylate histone (Mus musculus)


name: guanosine + NAD(+) <=> H(+) + N(2)-(ADP-D-ribosyl)-guanosine + nicotinamide


name: 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + dimethylallyl diphosphate <=> 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + diphosphate


name: Phosphorylated PER is phosphorylated by CK2 (Drosophila melanogaster)


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Danio rerio)


name: CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 (Mus musculus)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Danio rerio)


name: Aquaporins passively transport urea into cells (Sus scrofa)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + di-trans,octa-cis-undecaprenyl diphosphate <=> (Kdo)2-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Dictyostelium discoideum)


name: (2E)-geraniol + benzoyl-CoA <=> (2E)-geranyl benzoate + CoA


name: nocardicin G + S-adenosyl-L-methionine => H(+) + isonocardicin C + S-methyl-5'-thioadenosine


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Gallus gallus)


name: ATP + H2O + nitrate(out) => ADP + H(+) + nitrate(in) + phosphate


name: H(+) + keto-D-fructose + NADH = D-sorbitol + NAD(+)


name: (S)-lactate(in) + urate(out) = (S)-lactate(out) + urate(in)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain (Homo sapiens)


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Mus musculus)


name: Oligomerization of BAX at the mitochondrial membrane (Homo sapiens)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Homo sapiens)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Drosophila melanogaster)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Drosophila melanogaster)


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Mus musculus)


name: p-Y397-PTK2 binds SRC (Canis familiaris)


name: H2O2 + L-ascorbate => 2 H2O + L-dehydroascorbate


name: TDG excises 5-carboxylcytosine (Rattus norvegicus)


name: PTPRD binds SLITRK1-6 (Rattus norvegicus)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Bos taurus)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Dictyostelium discoideum)


name: MAF1 translocates to the nucleus (Bos taurus)


name: I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Rattus norvegicus)


name: SUMOylation of NR1H4 with SUMO1 (Bos taurus)


name: TNRC6A binds AGO2:miRNA (Drosophila melanogaster)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Canis familiaris)


name: ATP + CoA + pentadecanoate <=> AMP + diphosphate + pentadecanoyl-CoA


name: NAD(+) <=> 3'cADPR + H(+) + nicotinamide


name: ABC-type iron-sulfur cluster transporter activity


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)


name: L-serine + tRNA(Thr) => H2O + L-seryl-tRNA(Thr)


name: N-hydroxy-L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]


name: acetone + H(+) + NADH + O2 = H2O + hydroxyacetone + NAD(+)


name: 2-(3-methylsulfanyl)propylmalate + CoA + H(+) => 2-(5-methylsulfanyl)oxopentanoate + acetyl-CoA + H2O


name: JMJD6 demethylates Me2sR4-HIST1H4 (Sus scrofa)


name: acetyl-CoA + 6 H(+) + 5 malonyl-CoA + 2 NADPH => 2-hydroxy-5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 3 H2O + 2 NADP(+)


name: GDIs block activation of RHOG (Dictyostelium discoideum)


name: 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol <=> 1alpha,2beta,25-trihydroxycholecalciferol + 3-hydroxypropanal


name: TRAF6 is auto-ubiquitinated (Danio rerio)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Mus musculus)


name: glycyl-L-aspartate(out) + 2 H(+)(out) = glycyl-L-aspartate(in) + 2 H(+)(in)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: Cytosolic folate export across the plasma membrane (Mus musculus)


name: D-sorbitol + NADP(+) = D-glucose + H(+) + NADPH


name: MVD decarboxylates MVA5PP to IPPP (Danio rerio)


name: UDP-alpha-D-glucose + vitexin => H(+) + UDP + vitexin 2''-O-beta-D-glucoside


name: mitochondrial transcription factor activity


name: STUB1 polyubiquitinates RUNX2 (Canis familiaris)


name: sequestered tissue factor -> tissue factor (Homo sapiens)


name: Interleukin-1 family precursors are cleaved by caspase-1 (Canis familiaris)


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Gallus gallus)


name: acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)


name: AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA => adenosine(37) in tRNA + L-threonylcarbamoyladenylate


name: H2O + L-aspartate + NADP(+) => H(+) + NADPH + NH4(+) + oxaloacetate


name: 5-dehydro-D-gluconate + NADP(+) <=> 2,5-didehydro-D-gluconate + H(+) + NADPH


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Saccharomyces cerevisiae)


name: Activated type I receptor phosphorylates SMAD2/3 directly (Gallus gallus)


name: ADP + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP


name: GBF1 recruits ARF:GDP to the ERGIC (Mus musculus)


name: 2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = H(+) + hexadecanoate + sn-glycerol 3-phosphocholine


name: SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Homo sapiens)


name: a 5'-end dephospho-2'-deoxyribonucleoside-DNA + ATP <=> a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + ADP + H(+)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Homo sapiens)


name: inositol 1,3,4,5 tetrakisphosphate binding


name: (+)-copalyl diphosphate <=> diphosphate + miltiradiene


name: spermidine:feruloyl CoA N-acyltransferase activity


name: (6R)-L-erythro-6,7-dihydrobiopterin + H(+) + NADH => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NAD(+)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Bos taurus)


name: Conversion of C4 into C4a and C4b (Sus scrofa)


name: 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: H(+) + morphinone + NADH => morphine + NAD(+)


name: [glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O


name: Caspase-8 processing within TLR4 complex (Bos taurus)


name: PDE3B hydrolyses cAMP to AMP (Bos taurus)


name: 2-oxoglutarate + L-histidine => 3-(imidazol-5-yl)pyruvate + L-glutamate


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ADP + H(+) + phosphate => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ATP + H2O


name: (1S,2S)-1,2-dihydronaphthalene-1,2-diol + NADP(+) => H(+) + NADPH + naphthalene-1,2-diol


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Canis familiaris)


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Rattus norvegicus)


name: USP5 cleaves polyubiquitin (Canis familiaris)


name: CYP2J2 oxidises ARA (Dictyostelium discoideum)


name: P4HB mediates disulfide bond formation in Proinsulin (Sus scrofa)


name: CYP8B1 12-hydroxylates 4CHOL7aOLONE (Canis familiaris)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Danio rerio)


name: NTPDase3 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: (S)-2,3,4,5-tetrahydrodipicolinate + 2 H(+) + NADPH + NH4(+) => meso-2,6-diaminoheptanedioate + NADP(+)


name: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H(+) + NADPH => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+)


name: 5'-pApG-3' + H2O <=> 5'-ApG-3' + phosphate


name: an N-acyl-sphingoid base + UDP-alpha-D-galactose => a D-galactosylceramide + H(+) + UDP


name: GLI translocates to the nucleus (Mus musculus)


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Caenorhabditis elegans)


name: H2O + hexanal + NADP(+) => 2 H(+) + hexanoate + NADPH


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + diphosphate + GMP => a 3'-end 3'-phospho-ribonucleotide-RNA + GTP


name: 3-hydroxyisopentadecanoyl-CoA + NADP(+) => 3-oxoisopentadecanoyl-CoA + H(+) + NADPH


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)


name: ATP + holo-[peptidyl-carrier protein] + L-tryptophan <=> AMP + diphosphate + L-tryptophyl-[peptidyl-carrier protein]


name: COASY phosphorylates DP-CoA (Rattus norvegicus)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)