name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Homo sapiens)


name: Defective SLC2A10 does not transport Glc from extracellular region to cytosol (Homo sapiens)


name: Phosphorylation of Platelet Sec-1 (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine


name: SGSH hydrolyses Heparan sulfate chain(2) (Drosophila melanogaster)


name: Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Xenopus tropicalis)


name: chloride(out) + glycine(out) + 3 Na(+)(out) = chloride(in) + glycine(in) + 3 Na(+)(in)


name: Kinesin-5 is a homotetramer (Schizosaccharomyces pombe)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine => 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Saccharomyces cerevisiae)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => (R)-nephthenol + diphosphate


name: (2E)-octadecenoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + octadecanoyl-CoA + oxidized [electron-transfer flavoprotein]


name: carnosine(out) + 2 H(+)(out) = carnosine(in) + 2 H(+)(in)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Drosophila melanogaster)


name: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Rattus norvegicus)


name: IL24 binds IL20RA:JAK1:IL20RB (Rattus norvegicus)


name: 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate


name: apo-[BtrI ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[BtrI ACP]


name: D-tagatofuranose 1,6-bisphosphate <=> D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate


name: a 2-oxocarboxylate + L-asparagine => 2-oxosuccinamate + an L-alpha-amino acid


name: p-AMPK:AMP binds the ULK complex (Canis familiaris)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Canis familiaris)


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)


name: NUDT12 hydrolyses NADH to NMNH (Canis familiaris)


name: acetyl-CoA + L-seryl-[protein] <=> CoA + O-acetyl-L-seryl-[protein]


name: IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation  (Mus musculus)


name: 2,5-dicarboxyfuran + 2 H(+) + 3 H2O2 => 5-hydroxymethylfurfural + 2 H2O + 3 O2


name: CCND3,(CCND1,CCND2) binds RUNX1 (Gallus gallus)


name: a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase


name: G-protein coupled bile acid receptor binds lithocholic acid (Homo sapiens)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)


name: MTORC1 dissociates from ULK complex (Xenopus tropicalis)


name: DLD dimer dehydrogenates dihydrolipoyl (Homo sapiens)


name: (3R)-hydroxybutanoate pentamer + H2O <=> (3R)-hydroxybutanoate tetramer + (R)-3-hydroxybutanoate + H(+)


name: p-PKR dimer phosphorylates PPP2R5A (Bos taurus)


name: Activated protein C binds Protein S (Homo sapiens)


name: GDP-N,N'-diacetylbacillosamine + H2O = 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H(+)


name: Src phosphorylate WASP,N-WASP (Canis familiaris)


name: Low conductance potassium channels in pancreatic beta cells open in response to epinephrine (Homo sapiens)


name: H(+)(out) + shikimate(out) => H(+)(in) + shikimate(in)


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Homo sapiens)


name: ERBB4 ubiquitination by WWP1/ITCH (Bos taurus)


name: putrescine + spermidine = propane-1,3-diamine + sym-homospermidine


name: a short-chain (3R)-hydroxy fatty acyl-CoA + NAD(+) = a short-chain 3-oxoacyl-CoA + H(+) + NADH


name: CO binds to Cytochrome c oxidase (Bos taurus)


name: p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Rattus norvegicus)


name: TP53I3 oxidoreductase generates unstable semiquinones (Bos taurus)


name: DPP4(1-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Canis familiaris)


name: C-terminal L-cysteinyl-[HypE protein] + carbamoyl adenylate = AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + H(+)


name: ORC1 binds to H4K20me2 (Drosophila melanogaster)


name: PRMT1 arginine-methylates RUNX1 (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2 = dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+)


name: benzaldehyde + hydrogen cyanide <=> (S)-mandelonitrile


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Mus musculus)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Drosophila melanogaster)


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Sus scrofa)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Saccharomyces cerevisiae)


name: Interleukin-16 is secreted (Xenopus tropicalis)


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Canis familiaris)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Bos taurus)


name: CYP26A1,B1,C1 4-hydroxylate atRA (Homo sapiens)


name: kinetensin-(1-8) + L-leucine => H2O + kinetensin


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Mus musculus)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Xenopus tropicalis)


name: CoA + H(+) + N-terminal N(6)-hexadecanoylglycyl-[protein] => hexadecanoyl-CoA + N-terminal glycyl-[protein]


name: Formation of AT-AC C complex (Homo sapiens)


name: D-glucuronate + H(+) => D-glucurono-3,6-lactone + H2O


name: 3,3'-biflaviolin + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 flaviolin + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: A + H2O + spermidine = 4-aminobutanal + AH2 + propane-1,3-diamine


name: 4-hydroxy-17beta-estradiol + S-adenosyl-L-methionine <=> 4-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine


name: cholestanol + O2 + reduced [NADPH--hemoprotein reductase] => (22S)-22-hydroxycholestanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Rattus norvegicus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Dictyostelium discoideum)


name: GRK2 sequesters activated Gq (Bos taurus)


name: Thr-180 of ULK1 is phosphorylated (Bos taurus)


name: carnosine(out) + H(+)(out) = carnosine(in) + H(+)(in)


name: acetyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4 CO2 + 4 CoA + orcinol


name: ZnT1 mediates the efflux of zinc from the cell (Drosophila melanogaster)


name: PLK1 phosphorylates FIRRM at S43 (Gallus gallus)


name: a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + S-adenosyl-L-homocysteine => a 5'-end triphospho-guanosine-ribonucleotide-snRNA + S-adenosyl-L-methionine


name: Initial proteolyis of Ii by aspartic proteases to lip22 (Bos taurus)


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Mus musculus)


name: IL21:IL21R:JAK1 binds IL2RG:JAK3 (Mus musculus)


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine = 1,3,3'-tri-O-methyl-4alpha-mannobiose + H(+) + S-adenosyl-L-homocysteine


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Mus musculus)


name: GNRHR binds GNRHR peptide agonists (Bos taurus)


name: eicosanoyl-CoA + O2 <=> (2E)-eicosenoyl-CoA + H2O2


name: (+)-pulegone reductase, (-)-menthone as substrate, activity


name: (S)-4-hydroxymandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (E)-4-hydroxyphenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase]


name: Dissociation of the SPINK5:KLK5 complex at low pH (Sus scrofa)


name: AH2 + gentamicin X2 + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + A + geneticin + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Gallus gallus)


name: CCNK binds CDK13 (Dictyostelium discoideum)


name: Autophosphorylation of point mutants of ALK (Homo sapiens)


name: a 2,3-saturated fatty acid + H2O2 <=> a 3-hydroxy fatty acid + H2O


name: T2-induced deoxynucleotide kinase activity


name: PP2A mediated localization of RB1 protein in chromatin (Rattus norvegicus)


name: ESR1 binds ESR1 antagonists (Drosophila melanogaster)


name: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol


name: p-S256-Aquaporin-2 passively transports water into cell (Drosophila melanogaster)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Canis familiaris)


name: PKA/PKG phosphorylate Rap1GAP2 (Mus musculus)


name: 16S rRNA (guanine(966)-N(2))-methyltransferase activity


name: ITPA hydrolyses XTP to XMP (Dictyostelium discoideum)


name: Pks5 transforms LFCA adenylate ester to mycocerosyl (Mycobacterium tuberculosis)


name: Interaction of Bnip-2 with Cdc42 (Homo sapiens)


name: L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-glucose <=> 3''-deamino-3''-hydroxykanamycin X + H(+) + UDP


name: 2-dehydro-3-deoxy-D-gluconate(out) + H(+)(out) => 2-dehydro-3-deoxy-D-gluconate(in) + H(+)(in)


name: Phosphorylation and activation of VAV (Homo sapiens)


name: Caspase-mediated cleavage of Desmoglein 2 (Caenorhabditis elegans)


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Drosophila melanogaster)


name: acetyl-CoA + N-terminal L-cysteinyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-cysteinyl-[protein]


name: EPHB phosphorylates TIAM1 (Xenopus tropicalis)


name: H(+) + keto-D-tagaturonate + NADH => D-mannonate + NAD(+)


name: a ubiquinone + keto-D-fructose = 5-dehydro-D-fructose + a ubiquinol


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Sus scrofa)


name: putrescine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + S-methyl-5'-thioadenosine + spermidine


name: Mitochondrial BTD hydrolyses BCTN (Mus musculus)


name: mTORC1 phosphorylates AKT1S1 (Homo sapiens)


name: allulose 6-phosphate 3-epimerase activity


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Xenopus tropicalis)


name: 3,4-dihydroxybenzoate + bromide + 2 H(+) + NADPH + O2 => 3-bromo-4,5-dihydroxybenzoate + 2 H2O + NADP(+)


name: 1-nonadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Mus musculus)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Homo sapiens)


name: SUMOylation of HIPK2 with SUMO1 (Bos taurus)


name: 2 H(+) + O2 + 2 sulochrin => 2 (2R)-bisdechlorogeodin + 2 H2O


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)


name: a menaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine <=> 5'-deoxyadenosine + an 8-methylmenaquinone + 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(20)-[histone H4] + O2 => CO2 + formaldehyde + L-lysyl(20)-[histone H4] + succinate


name: apo-[aryl-carrier protein] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[aryl-carrier protein]


name: RCC1 stimulates GDP to GTP exchange on RAN (Schizosaccharomyces pombe)


name: H(+)(in) + phosphate(in) + sulfate(out) = H(+)(out) + phosphate(out) + sulfate(in)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Rattus norvegicus)


name: 3-methylbutanoyl-CoA + H2O = 3-methylbutanoate + CoA + H(+)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Canis familiaris)


name: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA = 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate


name: SCF-beta-TrCP ubiquitinylates IkB (Gallus gallus)


name: 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+) => 7,8-dihydroxykynurenate + O2


name: ROS oxidize thioredoxin and activate MAP3K5 (Saccharomyces cerevisiae)


name: BGN binds Collagen types I, VI, (IX) (Rattus norvegicus)


name: 5alpha-androst-1-ene-3,17-dione + A + H2O = 5alpha-androstan-1,3,17-trione + AH2


name: (9Z)-hexadecenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA


name: daidzein + O2 + reduced [NADPH--hemoprotein reductase] <=> 2'-hydroxydaidzein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SDH complex dehydrogenates succinate (Danio rerio)


name: a [peptide](out) + ATP + H2O = a [peptide](in) + ADP + H(+) + phosphate


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: 4-methylpentan-1-ol + NADP(+) => 4-methylpentanal + H(+) + NADPH


name: lithocholate + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + hyodeoxycholate + oxidized [NADPH--hemoprotein reductase]


name: RNF8 and RNF168 ubiquitinate H2AFX (Schizosaccharomyces pombe)


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Canis familiaris)


name: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O


name: S-adenosyl-L-methionine + tyramine <=> H(+) + N-methyltyramine + S-adenosyl-L-homocysteine


name: H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol = a fatty acid + H(+) + long chain 2-acyl-3-O-beta-D-galactosyl-sn-glycerol


name: Arachidonic acid is oxidised to 12R-HpETE by ALOX12B (Canis familiaris)


name: HSP90 is inactivated by binding to benzaquinoid ansamycins (Homo sapiens)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Schizosaccharomyces pombe)


name: (R)-reticuline + S-adenosyl-L-methionine => (R)-tembetarine + H(+) + S-adenosyl-L-homocysteine


name: JMJD1C demethylates H3K9 mono- and di-methylation (Homo sapiens)


name: ERBB2 T862A does not bind sapitinib (Homo sapiens)


name: RB1 translocates to the nucleus (Danio rerio)


name: PAF receptor binds platelet activating factor (Xenopus tropicalis)


name: IkB is ubiquitinated and degraded (Sus scrofa)


name: TMED2:TMED10 tetramer binds GPI anchored proteins (Gallus gallus)


name: isopentenyl diphosphate + neryl diphosphate <=> (2Z,6Z)-farnesyl diphosphate + diphosphate


name: Expression of ANGPTL3 regulated by NR1H2 or NR1H3 (Homo sapiens)


name: H2O + L-tryptophan => indole + NH4(+) + pyruvate


name: GALK1 phosphorylates Gal to Gal1P (Canis familiaris)


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Bos taurus)


name: glyoxylate + L-ornithine => 5-amino-2-oxopentanoate + glycine


name: HSD11B2 dehydrogenates PREDL to PREDN (Schizosaccharomyces pombe)


name: BTK in G alpha (12)-BTK complex is activated (Bos taurus)


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Xenopus tropicalis)


name: CLN3 transports GalCer to plasma membrane (Caenorhabditis elegans)


name: Release of mature NEDD8 (Schizosaccharomyces pombe)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Rattus norvegicus)


name: ethyl (9Z)-octadecenoate + H2O => (9Z)-octadecenoate + ethanol + H(+)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Gallus gallus)


name: a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H(+)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Bos taurus)


name: (+)-isomalbrancheamide B + chloride + FAD + 2 H(+) <=> (+)-malbrancheamide + FADH2


name: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H(+)


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Rattus norvegicus)


name: (R)-cembrene A + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: guanosine + phosphate => alpha-D-ribose 1-phosphate + guanine


name: 26S proteosome degrades ODC holoenzyme complex (Schizosaccharomyces pombe)


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Canis familiaris)


name: OPTN recruits CYLD to the TNFR1 complex (Bos taurus)


name: Type X collagen associates with collagen type II fibrils (Bos taurus)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Plasmodium falciparum)


name: Parkin transfers Ub to misfolded proteins (Schizosaccharomyces pombe)


name: PIAS4 SUMOylates VDR with SUMO2 (Danio rerio)


name: H(+) + N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine


name: aflatoxin reductase (coenzyme F420) activity


name: H2O + N-tetracosanoylsphinganine <=> sphinganine + tetracosanoate


name: PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs (Homo sapiens)


name: (2Z)-2-hydroxypenta-2,4-dienoate + fumarate + H(+) => (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O


name: dGTP + methylglyoxal <=> N(2)-(1-hydroxy-2-oxopropyl)-dGTP


name: Tyrosine phosphorylation of PRLR (Homo sapiens)


name: enterobactin transmembrane transporter activity


name: 2-oxoglutarate + D-lysine = 6-amino-2-oxohexanoate + D-glutamate


name: 2 H(+)(in) + orotate(in) => 2 H(+)(out) + orotate(out)


name: [protein]-C-terminal glycine + N-terminal glycyl-[protein] => a glycyl-glycyl-[protein] + H2O


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(out) => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(in)


name: ATP + cholate + CoA => AMP + choloyl-CoA + diphosphate


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Bos taurus)


name: (S)-1-phenylethanol + NAD(+) <=> acetophenone + H(+) + NADH


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Gallus gallus)


name: JAK2 is phosphorylated, activated (Mus musculus)


name: (9Z,12Z)-octadecadienoate + 1-hexadecanoylglycerone 3-phosphate = 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate


name: Creatine transport across the plasma membrane (Canis familiaris)


name: (S)-3-amino-2-methylpropanoate + pyruvate => (S)-2-methyl-3-oxopropanoate + L-alanine


name: eIF3 and eIF1A bind to the 40S subunit (Canis familiaris)


name: Integrin alphaIIb beta3 activation (Mus musculus)


name: Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Rattus norvegicus)


name: Defective HEXB does not cleave the terminal GalNAc from DS (Homo sapiens)


name: UCKL1 phosphorylates urindine, cytidine (Schizosaccharomyces pombe)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Bos taurus)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Mus musculus)


name: MTA2-NuRD complex deacetylates TP53 (Caenorhabditis elegans)


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Saccharomyces cerevisiae)


name: 3-bromo-4,5-dihydroxybenzoate + bromide + 3 H(+) + NADPH + O2 => 3,5-dibromobenzene-1,2-diol + CO2 + 2 H2O + NADP(+)


name: RAC1 and CDC42 activate PAK3 (Mus musculus)


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Canis familiaris)


name: STAMBPL1 is a deubiquitinase (Homo sapiens)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Bos taurus)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Mus musculus)


name: ATP + butanoate + CoA = AMP + butanoyl-CoA + diphosphate


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Gallus gallus)


name: Monoubiquitinated PTEN translocates to the nucleus (Gallus gallus)


name: G alpha (z) inhibits adenylate cyclase (Rattus norvegicus)


name: MAPK-dependent phosphorylation of KARS (Canis familiaris)


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Xenopus tropicalis)


name: all-trans-8'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + 2,6-dimethyldeca-2,4,6,8-tetraenedial


name: a 2'-deoxyribonucleoside 3'-phosphate + H2O <=> a 2'-deoxyribonucleoside + phosphate


name: 2,6-dihydroxypyridine + 4-(methylamino)butanoate + H(+) => 2,6-dihydroxypseudooxynicotine + H2O


name: butanal + H2O + NADP(+) <=> butanoate + 2 H(+) + NADPH


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Danio rerio)


name: SUMOylation of MDC1 with SUMO2,3 (Mus musculus)


name: anthranilate + S-adenosyl-L-methionine => O-methyl anthranilate + S-adenosyl-L-homocysteine


name: L-asparaginyl-[protein] + NAD(+) <=> H(+) + N(4)-(ADP-D-ribosyl)-L-asparaginyl-[protein] + nicotinamide


name: an anthocyanidin 3,5-di-O-beta-D-glucoside + 2 H(+) + UDP => an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose


name: P2Y2 receptor binds ATP and UTP (Xenopus tropicalis)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP + H2O => (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dCMP


name: AH2 + ATP + ilicicolinate B => A + AMP + diphosphate + ilicicolin B


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Canis familiaris)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Danio rerio)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Danio rerio)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)


name: 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate => 1D-myo-inositol hexakisphosphate + H2O


name: 1-octadecanoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoserine + 9,10-epoxyoctadecanoate + H(+)


name: H(+) + L-arginine + L-canaline => L-canavanine + L-ornithine


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Canis familiaris)


name: menaquinol-8 + nitrate <=> H2O + menaquinone-8 + nitrite


name: a secondary alkyl amine + H2O + NADP(+) => a ketone + H(+) + NADPH + NH4(+)


name: 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + H(+) + UDP


name: Activated FGFR3:p-FRS bind to PPTN11 (Bos taurus)


name: Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 (Gallus gallus)


name: beta-D-glucosyl crocetin + UDP-alpha-D-glucose => bis(beta-D-glucosyl) crocetin + UDP


name: (4R)-hydroxyeicosasphinganine + a fatty acyl-CoA => CoA + H(+) + N-acyl-4-hydroxyeicosasphinganine


name: DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)


name: Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Dictyostelium discoideum)


name: FURIN translocates to the plasma membrane (Bos taurus)


name: 4-aminobutanoate + ATP + L-histidine => ADP + H(+) + L-homocarnosine + phosphate


name: DLD dimer dehydrogenates dihydrolipoyl (Homo sapiens)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Saccharomyces cerevisiae)


name: cis-2-enoyl-CoA reductase (NADPH) activity


name: a tetracycline + H(+) + NADPH + O2 = a (1S,10aS)-3-(CONH2)-1-(Me2N)-3,3a,4,6-(HO)4-2,5-dioxo-1H,10aH,11H,11aH-cyclopenta[b]anthracene + CO + H2O + NADP(+)


name: S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + H(+) + S-methyl-5'-thioadenosine


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)


name: a chlorophyll + H2O => a chlorophyllide + H(+) + phytol


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Rattus norvegicus)


name: 2-hydroxyethane-1-sulfonate + NAD(+) <=> H(+) + NADH + sulfoacetaldehyde


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Rattus norvegicus)


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Mus musculus)


name: Exchange of oxygen with sulfur in MoCo (Canis familiaris)


name: Autoubiquitination of phospho-COP1(Ser-387 ) (Sus scrofa)


name: a 1,2-saturated acyl-CoA + an acyl-CoA + H2O => an (R)-2-alkyl-3-oxoalkanoate + 2 CoA + H(+)


name: erythromycin C + H2O + NADP(+) => erythromycin D + H(+) + NADPH + O2


name: IP receptor can bind prostacyclin (Canis familiaris)


name: chloride(out) + L-valine(out) + 2 Na(+)(out) = chloride(in) + L-valine(in) + 2 Na(+)(in)


name: 3-hydroxypyruvate + H(+) => CO2 + glycolaldehyde


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: Interaction of Tie2 and p85 of PI3K (Canis familiaris)


name: D-galactosamine 6-phosphate => alpha-D-galactosamine 1-phosphate


name: proton-transporting ATP synthase activity, rotational mechanism


name: D-cellotetraonate + H(+) => D-cellotetraono-1,5-lactone + H2O


name: depalmitoylated eNOS translocates from plasma membrane (Saccharomyces cerevisiae)


name: NADP(+) + nicotinate <=> nicotinamide + nicotinate-adenine dinucleotide phosphate


name: a 2-oxocarboxylate + H(+) + NADH + NH4(+) => an L-alpha-amino acid + H2O + NAD(+)


name: dGDP(out) + UTP(in) <=> dGDP(in) + UTP(out)


name: (-)-yatein + 2-oxoglutarate + O2 => (-)-deoxypodophyllotoxin + CO2 + H2O + succinate


name: small RNA binding translational repressor activity


name: 2,3-didehydroadipoyl-CoA + acetyl-CoA <=> 3-oxo-5,6-didehydrosuberyl-CoA + CoA


name: estrone 3-sulfate(out) + pentanoate(in) <=> estrone 3-sulfate(in) + pentanoate(out)


name: [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n) + n ATP + n D-aspartate => [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + n ADP + n H(+) + n phosphate


name: beta-amyrin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 11-oxo-beta-amyrin + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane (Homo sapiens)


name: H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol <=> a fatty acid + H(+) + long chain 2-acyl-3-O-beta-D-galactosyl-sn-glycerol


name: SHC1 phosphorylation by ERBB2 heterodimers (Drosophila melanogaster)


name: VEGFA gene expression is inhibited by the TFAP2A homodimer (Homo sapiens)


name: H(+) + NADPH + O2 + theobromine = 7-methylxanthine + formaldehyde + H2O + NADP(+)


name: NRXNs bind CASK:Protein 4.1 (Bos taurus)


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Rattus norvegicus)


name: SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Sus scrofa)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Rattus norvegicus)


name: Latent TGF-beta-1 is cleaved by FURIN (Mus musculus)


name: (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 = (3R,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: (2E)-tetradecenedioyl-CoA + H2O = (3S)-hydroxytetradecanedioyl-CoA


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + H2O + 2 oxidized [adrenodoxin]


name: p-S MAPK6,4 phosphorylate MAPKAPK5 (Bos taurus)


name: alpha-eudesmol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: PTPN11 binds p-Y759-IL6ST (Gallus gallus)


name: 4-deoxy-6-O-methyl-L-threo-hex-4-enopyranuronate + [(1->4)-alpha-D-galacturonosyl methyl ester](n-1) => [(1->4)-alpha-D-galacturonosyl methyl ester](n)


name: H(+) + NADPH + vanillin <=> 4-hydroxy-3-methoxy-benzenemethanol + NADP(+)


name: an omega-oxo fatty acid + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => an omega-hydroxy fatty acid + O2 + reduced [NADPH--hemoprotein reductase]


name: L-cysteine + O-succinyl-L-homoserine = H(+) + L,L-cystathionine + succinate


name: H2O + N(2),6-disulfo-D-glucosamine => H(+) + N-sulfo-D-glucosamine + sulfate


name: adenosine 2',5'-bisphosphate + H2O <=> AMP + phosphate


name: Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 (Drosophila melanogaster)


name: 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + beta-D-Gal-(1<->1')-Cer


name: 15-methylhexadecasphinganine + a carboxylate => H2O + N-acyl-15-methylhexadecasphinganine


name: 2-oxoglutarate(out) + hexanedioate(in) => 2-oxoglutarate(in) + hexanedioate(out)


name: alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + UDP-N-acetyl-alpha-D-glucosamine => alpha-D-Man-(1->3)-[alpha-D-GlcNAc-(1->2)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + H(+) + UDP


name: 3-hydroxyisoheptadecanoyl-CoA + NADP(+) = 3-oxoisoheptadecanoyl-CoA + H(+) + NADPH


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Schizosaccharomyces pombe)


name: a dicarboxylate(in) + dehydroepiandrosterone 3-sulfate(out) = a dicarboxylate(out) + dehydroepiandrosterone 3-sulfate(in)


name: chorismate + NH4(+) <=> 4-amino-4-deoxychorismate + H2O


name: 4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH <=> 3 CO2 + 4 CoA + H2O + isoliquiritigenin + NADP(+)


name: SUMOylation of TDG with SUMO2,3 (Rattus norvegicus)


name: SLC46A1 transports hemes from extracellular region to cytosol (Sus scrofa)


name: Squalene is oxidized to its epoxide (Bos taurus)


name: Dermatan sulfate can be further sulfated on position 2 of iduronate (Canis familiaris)


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Sus scrofa)


name: WNTs are secreted in exosomes (Xenopus tropicalis)


name: 6-hydroxy-L-homoarginine <=> (S)-2-amino-6-oxohexanoate + guanidine


name: (11Z)-eicosenoyl-CoA + H(+) + malonyl-CoA => (13Z)-3-oxodocosenoyl-CoA + CO2 + CoA


name: Na(+)(out) + uridine(out) = Na(+)(in) + uridine(in)


name: NH4(+) + uridine => cytidine + H(+) + H2O


name: a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine => 1-hexadecanoyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: 2 H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UMP => H2O + UDP-N-acetyl-alpha-D-galactosamine


name: 2 A + 2 AMP + 2 diphosphate + H(+) + N-benzoyl-L-phenylalaninol => 2 AH2 + 2 ATP + benzoate + L-phenylalanine


name: pseudouridine(2604) in 23S rRNA => uridine(2604) in 23S rRNA


name: AH2 + cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + A + cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: guanosine 3'-diphosphate 5'-triphosphate + H2O <=> diphosphate + GTP + H(+)


name: Cleavage of ERBB4m80 by gamma-scretase complex (Caenorhabditis elegans)


name: (2R)-3-phospho-glyceroyl phosphate + 2-deoxy-alpha-D-ribose 1-phosphate => (2R)-3-phosphoglycerate + 2-deoxy-alpha-D-ribose 1,5-bisphosphate + H(+)


name: GTP-binding activates eEF2 (Mus musculus)


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: AMP + diphosphate + flavunoidine + H(+) => (2S)-5,5-dimethylpiperidine-2-carboxylate + 10-hydroxy-pre-flavunoidine + ATP


name: alpha-D-glucose 1-phosphate => alpha-D-glucose 6-phosphate


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Saccharomyces cerevisiae)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Saccharomyces cerevisiae)


name: 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H(+)


name: 4-thiouridine 5'-phosphate + ADP + H(+) => 4-thiouridine + ATP


name: Dissociation of L13a from the 60s ribosomal subunit (Plasmodium falciparum)


name: Noradrenaline translocates to the cytosol (Homo sapiens)


name: a monoamide of a dicarboxylate + H2O = a dicarboxylate + NH4(+)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Canis familiaris)


name: D-ribitol 1-phosphate + H2O <=> phosphate + ribitol


name: AKR1B1 reduces Glc to D-sorbitol (Mus musculus)


name: 2 H(+) + N(6)-dimethyladenosine(2085) in 23S rRNA + 2 S-adenosyl-L-homocysteine => adenosine(2085) in 23S rRNA + 2 S-adenosyl-L-methionine


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-hexanoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: dAMP(in) + NAD(+)(out) = dAMP(out) + NAD(+)(in)


name: oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor


name: 3-hydroxyicosanoyl-CoA + NADP(+) = 3-oxoeicosanoyl-CoA + H(+) + NADPH


name: gibberellin A9 carboxyl methyltransferase activity


name: LTBP1, LTBP3 bind TGF-Beta (Homo sapiens)


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Saccharomyces cerevisiae)


name: CoA + H(+) + N-dodecanoyl-taurine => dodecanoyl-CoA + taurine


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Xenopus tropicalis)


name: 3-methylbutanol + NAD(+) => 3-methylbutanal + H(+) + NADH


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Homo sapiens)


name: 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+) => L-dopa + O2


name: Association of NuMA with microtubules (Homo sapiens)


name: NPAS4 binds INS gene promoter (Homo sapiens)


name: 5-(methylsulfanyl)-D-ribose + ATP => ADP + H(+) + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: LC3 de-lipidation by ATG4 (Dictyostelium discoideum)


name: (R)-2-methyl-3-oxopropanoate + CoA + H2O + NAD(+) => H(+) + hydrogencarbonate + NADH + propanoyl-CoA


name: AAMP binds EGFR (Caenorhabditis elegans)


name: NCOA3 binds ESR1:estrogen:TFGA gene (Mus musculus)


name: 1-deoxysphinganine + a fatty acyl-CoA => CoA + H(+) + N-acyl-1-deoxysphinganine


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: CBL binds and ubiquitinates phosphorylated Sprouty (Canis familiaris)


name: p-BMAL1:p-CLOCK,NPAS2 binds BHLHE41 (DEC2) gene (Homo sapiens)


name: isopyridoxal + NAD(+) <=> 5-pyridoxolactone + H(+) + NADH


name: Ub-RibC-AXIN is degraded by the proteasome (Homo sapiens)


name: 7-methylxanthine + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + theobromine


name: (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + homogentisate => 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate


name: TORC2 complex phosphorylates SGK1 (Canis familiaris)


name: Formation of soluble VTN:C5b-C9  (Canis familiaris)


name: Phosphorylation of SLP-76 by p-SYK (Rattus norvegicus)


name: Translocation of active Cdc25C to the nucleus (Drosophila melanogaster)


name: glutarate(out) + urate(in) => glutarate(in) + urate(out)


name: 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA => a 1-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA


name: PXLP-K56-SRR dimer deaminates D-Ser (Dictyostelium discoideum)


name: CBLL1 binds SRC-phosphorylated CDH1 complex (Homo sapiens)


name: PGM1:Mg2+ isomerises G1P to G6P (Drosophila melanogaster)


name: POLB-mediated DNA strand displacement synthesis (Sus scrofa)


name: H2O + S-(1-hydroxy-3-methylhexan-3-yl)-L-cysteine => 3-methyl-3-sulfanylhexan-1-ol + NH4(+) + pyruvate


name: AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate = A + semiviriditoxin


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Gallus gallus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-oxononanoate + H(+) => 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O


name: TDP1 and TDP2 process unligatable DSB ends (Gallus gallus)


name: p-S10 CDKN1B translocates to the cytosol (Gallus gallus)


name: NOTCH1 associates with negative regulators NUMB and ITCH (Homo sapiens)


name: 4-methylpent-2-enoyl-CoA + H2O => (R)-2-hydroxy-4-methylpentanoyl-CoA


name: adenosine 3',5'-bisphosphate + H(+) + S-alkyl thiosulfate => 3'-phosphoadenylyl sulfate + a thiol


name: Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Mus musculus)


name: 3',5-dihydroxy-3,4',7-trimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine


name: FUK phosphorylates beta-Fuc to Fuc1P (Rattus norvegicus)


name: (1H-indol-3-yl)-N-methylmethanamine + S-adenosyl-L-methionine = gramine + H(+) + S-adenosyl-L-homocysteine


name: estrone 3-sulfate(in) => estrone 3-sulfate(out)


name: OCT2 mediates tubular uptake of organic cations in the kidney (Sus scrofa)


name: Activated FGFR3 phosphorylates SHC1 (Canis familiaris)


name: SMG6 hydrolyzes mRNA with premature termination codon (Mus musculus)


name: AKT phosphorylates IKKalpha (Danio rerio)


name: SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Mus musculus)


name: Dissociation of the Gi alpha:G olf complex (Rattus norvegicus)


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Danio rerio)


name: a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+) => a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: 2 H(+) + 2 NADPH + 2 O2 + tetracenomycin B2 => 8-demethyltetracenomycin C + H2O + 2 NADP(+)


name: 4 H(+) + 6 H2O + ophiobolin C + 4 oxidized [NADPH--hemoprotein reductase] => 4 O2 + ophiobolin F + 4 reduced [NADPH--hemoprotein reductase]


name: hydroxyacetone + NAD(+) => H(+) + methylglyoxal + NADH


name: RHOT2 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: 2 H(+) + hexadecanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (4Z)-hexadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (S)-lactate + L-phenylalanine = H2O + N-[(S)-lactoyl]-L-phenylalanine


name: glycoursodeoxycholate(out) + 2 Na(+)(out) => glycoursodeoxycholate(in) + 2 Na(+)(in)


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Bos taurus)


name: glycine(in) + H(+)(in) <=> glycine(out) + H(+)(out)


name: CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+) => 2 H(+) + 2 H2O + N(2)-succinyl-L-arginine


name: (2S,9S)-annullatin H + 2 A = (2S,9S)-annullatin D + 2 AH2


name: S100A7 or S100A7A binds Zn2+ (Bos taurus)


name: L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: hZIP5 mediates zinc uptake by cells (Homo sapiens)


name: MTMR6 binds MTMR9 (Schizosaccharomyces pombe)


name: Collagen IX is cross-linked to the surface of collagen type II fibrils (Canis familiaris)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Bos taurus)


name: p52:RELB translocates from cytosol to nucleus (Mus musculus)


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Danio rerio)


name: 3-carboxy-2-oxobutanoate + H(+) + NADH => (2R,3S)-3-methylmalate + NAD(+)


name: dGMP + inosine => 2'-deoxyguanosine + IMP


name: a 2-(omega-methylsulfanyl)alkylmalate = a 3-(omega-methylsulfanyl)alkylmalate


name: auxin influx transmembrane transporter activity


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Danio rerio)


name: XYLTs transfer Xyl to core protein (Caenorhabditis elegans)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: 2 H(+) + H2O + N-carbamoyl-L-aspartate = CO2 + L-aspartate + NH4(+)


name: H2O + N-(4-aminobutylpyrrolinium) ion + O2 <=> H2O2 + N-(4-oxobutylpyrrolinium) ion + NH4(+)


name: Translocation of Vav1 to CD28 (Canis familiaris)


name: PAK1 phosphorylates FLNA (Caenorhabditis elegans)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 <=> N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate


name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol (Bos taurus)


name: CDC14A,B bind MAPK6 (Xenopus tropicalis)


name: De novo formation of eIF2:GTP (Homo sapiens)


name: HMOX1 translocates from the cytosol to the nucleoplasm (Danio rerio)


name: PTK2 binds activated MET (Caenorhabditis elegans)


name: H2O + L-cysteine = H(+) + hydrogen sulfide + NH4(+) + pyruvate


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Homo sapiens)


name: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Xenopus tropicalis)


name: alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose <=> beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 H(+) + 2 UDP


name: D-cysteine(out) + L-alanine(in) <=> D-cysteine(in) + L-alanine(out)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Sus scrofa)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene = 1,2,4-trichlorobenzene + chloride + H(+)


name: H2O + S-[(2E,6E,10E)-geranylgeranyl]-L-glutathione => L-glutamate + S-[(2E,6E,10E)-geranylgeranyl]-L-cysteinylglycine


name: acetate + ATP + holo-[citrate lyase ACP] <=> acetyl-[citrate lyase ACP] + AMP + diphosphate


name: 1-(1Z-octadecenyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine => 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: H(+) + loliose + UDP => sucrose + UDP-alpha-D-galactose


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Sus scrofa)


name: Alpha-1-Microglobulin is cleaved (Homo sapiens)


name: Defective SRD5A3 does not reduce pPNOL to DCHOL (Homo sapiens)


name: 2-oxoglutarate + L-arginine + O2 <=> 5-hydroxy-L-arginine + CO2 + succinate


name: a carboxylate + ergosterol + H(+) => ergosteryl ester + H2O


name: [thioredoxin]-disulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin]


name: RET binds GFRA1,GFRA3 (Caenorhabditis elegans)


name: 2 Fe(III)-[cytochrome c] + H2O + lupanine = 17-hydroxylupanine + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: "lupanine 17-hydroxylase (cytochrome c)"


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Saccharomyces cerevisiae)


name: O2 + reduced [NADPH--hemoprotein reductase] + secologanin <=> 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + secoxyloganin


name: XPO1-dependent export of p-S69,S73 MITF-M (Drosophila melanogaster)


name: PSGs bind proteoglycans and TGF-beta1 (Xenopus tropicalis)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Homo sapiens)


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Homo sapiens)


name: 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oyl-CoA + AMP + diphosphate => 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oate + ATP + CoA


name: NEU1 hydrolyses Neu5Ac from glycoconjugates (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphoethanolamine


name: acacetin + H(+) + S-adenosyl-L-homocysteine => apigenin + S-adenosyl-L-methionine


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine => [thioredoxin]-dithiol + H(+) + phosphate + sarcosine


name: p-Y420-FYN is phosphorylated on S21 (Bos taurus)


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Sus scrofa)


name: 1,2-dioctanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O => H(+) + octanoate + octanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: (glutathione)4[2Fe(III)-2S] cluster(in) + ATP + H2O = (glutathione)4[2Fe(III)-2S] cluster(out) + ADP + H(+) + phosphate


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Canis familiaris)


name: 27-hydroxysterol binds ESR1, ESR2 (Bos taurus)


name: BCL2 binds BCL2 antagonists (Canis familiaris)


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Xenopus tropicalis)


name: proton-transporting ATPase activity, rotational mechanism


name: Association of GABA B receptor with G protein beta-gamma subunits (Bos taurus)


name: p-STAT1 dimer binds KPNA1 (Canis familiaris)


name: adenosine(1618) in 23S rRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(1618) in 23S rRNA + S-adenosyl-L-homocysteine


name: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Canis familiaris)


name: ornithine => putrescine + CO2 (Xenopus tropicalis)


name: dGMP(in) + NAD(+)(out) <=> dGMP(out) + NAD(+)(in)


name: MFAP2, MFAP5 bind microfibrils (Rattus norvegicus)


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Sus scrofa)


name: protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity


name: L-tyrosyl-L-isoleucyl-L-leucine + neurotensin(1-10) => H2O + neurotensin


name: Autophosphorylation of PDGF alpha/beta receptors (Gallus gallus)


name: RNA(n)-3'-guanine ribonucleotide => 2',3'-cyclophospho-GMP + RNA(n)


name: 3'-phosphoadenylyl sulfate + a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol <=> 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+)


name: RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Rattus norvegicus)


name: H(+) + NADH + O2 + salicylate = 2,5-dihydroxybenzoate + H2O + NAD(+)


name: 2 H2O + ITP <=> 2 H(+) + IMP + 2 phosphate


name: Activated FGFR4 phosphorylates PPTN11 (Gallus gallus)


name: IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Bos taurus)


name: aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH4(+) => H(+) + 4 H2O + phosphate + pyridoxal 5'-phosphate


name: 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + nonanedioate


name: Formation of the CE:GMP intermediate complex (Gallus gallus)


name: diphosphate + phenylacetyl-AMP => 2-phenylacetate + ATP + H(+)


name: (+)-sesamin dicatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) => (+)-sesamin monocatechol + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Sus scrofa)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Homo sapiens)


name: IRAK4 is activated by autophosphorylation (Homo sapiens)


name: CRLF1:IL27 translocates to the extracellular region (Canis familiaris)


name: N-acetylserotonin + S-adenosyl-L-methionine => H(+) + melatonin + S-adenosyl-L-homocysteine


name: K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Bos taurus)


name: Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Gallus gallus)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Mus musculus)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Canis familiaris)


name: SLC22A18 exchanges extracellular organic cations for cytosolic H+ (Sus scrofa)


name: acetyl-CoA + aminomethylphosphonate <=> 2-N-acetamidomethylphosphonate + CoA


name: Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate (Homo sapiens)


name: tBID binds to inactive BAK protein (Gallus gallus)


name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter (Homo sapiens)


name: Transport of VPU to Plasma Membrane (Homo sapiens)


name: 5,6,7,8-tetrahydromethanopterin + A <=> 7,8-dihydromethanopterin + AH2


name: WWTR1 binds SMAD2/3:SMAD4 heterotrimer (Sus scrofa)


name: 4,8-dihydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase] <=> 4,5,8-trihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Mus musculus)


name: 2 H(+)(in) + L-alanyl-L-aspartate(in) => 2 H(+)(out) + L-alanyl-L-aspartate(out)


name: PI3K binds membrane-associated estrogen receptors (Gallus gallus)


name: Elongation of pre-rRNA transcript (Schizosaccharomyces pombe)


name: ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Caenorhabditis elegans)


name: UBQLNs bind UIM-containing adaptor proteins (Gallus gallus)


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Gallus gallus)


name: an N-acetoxyarylamine + CoA => acetyl-CoA + an N-hydroxyarylamine


name: VTN binds collagens I, IV and VI (Homo sapiens)


name: baicalein + UDP-alpha-D-glucuronate <=> baicalin + UDP


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 1-O-methyl-(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatrienoate


name: H2O + N-(octadecanoyl)-sphinganine = octadecanoate + sphinganine


name: DCN binds collagen I, II, III, VI fibrils (Canis familiaris)


name: IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex  (Homo sapiens)


name: Addition of galactose to Core 6 glycoprotein (Homo sapiens)


name: Autophosphorylation of SRC (Rattus norvegicus)


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Saccharomyces cerevisiae)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Caenorhabditis elegans)


name: Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Homo sapiens)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Bos taurus)


name: CYP3A4 binds CYP3A4 inhibitors (Mus musculus)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Saccharomyces cerevisiae)


name: Cleavage of p-STK3 (p-MST2) by caspase 3 (Xenopus tropicalis)


name: Dissociation of BRAF/RAF fusion complex (Homo sapiens)


name: Active ALK phosphorylates PLCG1 (Canis familiaris)


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Rattus norvegicus)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Dictyostelium discoideum)


name: 2-oxoglutarate + cephalosporin C => (7R)-7-(5-carboxy-5-oxopentanamido)deacetylcephalosporanate + D-glutamate


name: ATP + streptidine <=> 6-O-adenylylstreptidine + diphosphate


name: (R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = AMP + diphosphate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: 2 H(+)(in) + nitrate + ubiquinol-8 = 2 H(+)(out) + H2O + nitrite + ubiquinone-8


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Canis familiaris)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Bos taurus)


name: a sphingoid base + ATP <=> a sphingoid 1-phosphate + ADP + H(+)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Sus scrofa)


name: (R)-glycerate + NAD(+) => 3-hydroxypyruvate + H(+) + NADH


name: N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine = N-acyl-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoate (4E)-octadecasphin-4-enine


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Canis familiaris)


name: CYP3A4 binds CYP3A4 inhibitors (Homo sapiens)


name: FPGS-2 transforms THF to THFPG (Drosophila melanogaster)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane (Sus scrofa)


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Canis familiaris)


name: GSTO1 dimer reduces methylarsonate to methylarsonite (Caenorhabditis elegans)


name: [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine


name: BRISC complex deubiquitinates NLRP3 (Gallus gallus)


name: AH2 + O2 + pregna-4,9(11)-diene-3,20-dione => 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O


name: 1,4-dihydroxy-2-naphthoate + all-trans-undecaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-11 + CO2 + diphosphate


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Rattus norvegicus)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Gallus gallus)


name: Internal Methylation of mRNA (Xenopus tropicalis)


name: JAK2 transphosphorylates and is activated in response to Erythropoietin (Homo sapiens)


name: class II DNA-(apurinic or apyrimidinic site) endonuclease activity


name: SodB reduces superoxide to H2O2 (Homo sapiens)


name: (6E)-8-hydroxygeranial + NAD(+) = (6E)-8-oxogeranial + H(+) + NADH


name: Disassociation and translocation of STATs to the nucleus (Sus scrofa)


name: TP53 stimulates APAF1 gene expression (Homo sapiens)


name: luteolin + UDP-alpha-D-glucuronate => H(+) + luteolin 7-O-beta-D-glucuronide + UDP


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O => 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Sus scrofa)


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Bos taurus)


name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Bos taurus)


name: HAO2 tetramer oxidises 2OH-PALM (Sus scrofa)


name: Mcm4,6,7 trimer forms and associates with the replication fork (Xenopus tropicalis)


name: Formation of Cyclin E:Cdk2 complexes (Bos taurus)


name: Spherical HDL binds membrane-associated free cholesterol and phospholipids (Bos taurus)


name: dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine => dTDP-alpha-D-forosamine + H(+) + S-adenosyl-L-homocysteine


name: Interleukin-5 receptor alpha subunit binds Interleukin-5 (Mus musculus)


name: Furin cleaves pro-factor X to factor X (Homo sapiens)


name: Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)5 (PP-Dol)1 by ALG3 (Homo sapiens)


name: Co-precorrin-7 + S-adenosyl-L-methionine = Co-precorrin-8X + H(+) + S-adenosyl-L-homocysteine


name: H(+) + L-valine = 2-methylpropan-1-amine + CO2


name: O-acetyl-L-serine + pyrazole => 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)


name: GUK1 phosphorylates 6TGMP to 6TGDP (Homo sapiens)


name: Recruitment of CstF to the CPSF Bound Pre-mRNA (Drosophila melanogaster)


name: chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 3,8-divinyl chlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate => alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Schizosaccharomyces pombe)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Canis familiaris)


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Xenopus tropicalis)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Xenopus tropicalis)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Caenorhabditis elegans)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Caenorhabditis elegans)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Drosophila melanogaster)


name: cholesterol + NADP(+) <=> 7-dehydrocholesterol + H(+) + NADPH


name: (6E)-8-hydroxygeraniol + NAD(+) = (6E)-8-hydroxygeranial + H(+) + NADH


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Canis familiaris)


name: Bitter compound binds bitter taste receptor (TAS2R) (Danio rerio)


name: an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] => a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: (S)-eriodictyol + 2-oxoglutarate + O2 = (2R,3R)-dihydroquercetin + CO2 + succinate


name: A + H2O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH2


name: ATP + methylphosphonate <=> adenine + alpha-D-ribose 1-methylphosphonate 5-triphosphate


name: (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate => (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2


name: H2O + L-isoleucine-(+)-12-hydroxy-7-isojasmonate => L-isoleucine + tuberonate


name: Hemoglobin A binds O2, releasing H+ and CO2 (Homo sapiens)


name: ABCG4 may mediate cholesterol efflux (Gallus gallus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: (4S)-4-hydroxy-L-glutamate + H(+) + NADH => (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + 2 H2O + NAD(+)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Canis familiaris)


name: 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O <=> (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+)


name: USP10 deubiquitinates SNX3, CFTR (Mus musculus)


name: rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity


name: (2E)-butenoyl-CoA + (R)-carnitine = CoA + O-(2E)-butenoyl-(R)-carnitine


name: JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Rattus norvegicus)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Homo sapiens)


name: SUMOylation of CREBBP with SUMO1 (Homo sapiens)


name: Cis-homodimerization of nectins (Homo sapiens)


name: a ribonucleoside 5'-diphosphate + ADP => a ribonucleoside 5'-phosphate + ATP


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Dictyostelium discoideum)


name: ub UBXN7 is degraded by the 26S proteasome (Schizosaccharomyces pombe)


name: (2E,13Z)-eicosadienoyl-CoA + H2O => (R)-3-hydroxy-(13Z)-eicosenoyl-CoA


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Dictyostelium discoideum)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Mus musculus)


name: H(+) + N(2)-acetyl-L-citrulline + phosphate => carbamoyl phosphate + N(2)-acetyl-L-ornithine


name: a [peptide](out) + ATP + H2O <=> a [peptide](in) + ADP + H(+) + phosphate


name: hexadecan-1-ol + NAD(+) <=> H(+) + hexadecanal + NADH


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose <=> a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + H(+) + UDP


name: RAC2 translocates to the phagocytic vesicle membrane (Bos taurus)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Dictyostelium discoideum)


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Gallus gallus)


name: H(+) + O-phospho-L-threonine => (R)-1-aminopropan-2-yl phosphate + CO2


name: H(+) + H2O + NADP(+) + rifampicin para-naphthoquinone carboxamide => NADPH + O2 + rifampicin


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Rattus norvegicus)


name: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate


name: PE is converted to PS by PTDSS2 (Mus musculus)


name: ZnT1 mediates the efflux of zinc from the cell (Sus scrofa)


name: PI4P transports from the Golgi membrane to the plasma membrane (Homo sapiens)


name: (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Canis familiaris)


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Danio rerio)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Canis familiaris)


name: hexadecanoyl-CoA + O2 => (2E)-hexadecenoyl-CoA + H2O2


name: 3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O2 <=> 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Mus musculus)


name: eIF3 and eIF1A bind to the 40S subunit (Homo sapiens)


name: L-aspartate(in) + L-glutamine(out) <=> L-aspartate(out) + L-glutamine(in)


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Homo sapiens)


name: LTBP1, LTBP3 bind TGF-Beta (Mus musculus)


name: (9E)-octadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,9E)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-glucuronate <=> 3-O-[beta-D-GlcA-(1->3)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP


name: D-fructose + D-glucose <=> D-glucono-1,5-lactone + D-sorbitol


name: (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4(+) => H2O + O2 + serotonin


name: POU5F1 (OCT4), SOX2, NANOG, KLF4, PBX1, SMAD2 bind the NANOG promoter (Homo sapiens)


name: RDH12 reduces atRAL to atROL (Sus scrofa)


name: TRAIL-mediated dimerization of procaspase-8 (Sus scrofa)


name: Synthesis of dolichyl-phosphate-glucose (Gallus gallus)


name: a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H2O => a 3-carboxymethyl-3-hydroxyacyl-[ACP]


name: argininosuccinate <=> fumarate + arginine (Rattus norvegicus)


name: RAC1:GTP binds NOX1 complex (Mus musculus)


name: Interaction of PECAM-1 and SHP-1 (Sus scrofa)


name: 6-amino-2-oxohexanoate + H2O2 => 5-aminopentanoate + CO2 + H2O


name: diphosphate + talarodiene => (2E,6E,10E)-geranylgeranyl diphosphate


name: EPOR binds EPOR agonists (Canis familiaris)


name: a fatty acid + beta-D-glucosyl-(1<->1)-sphing-4-enine => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O


name: Carbonic anhydrase dehydrates bicarbonate (plasma membrane) (Caenorhabditis elegans)


name: (13Z)-docosenoyl-CoA + sphing-4-enine => CoA + H(+) + N-(13Z-docosenoyl)-sphing-4-enine


name: benzil + H(+) + NADPH => (S)-benzoin + NADP(+)


name: ATP + CoA + undecanoate => AMP + diphosphate + undecanoyl-CoA


name: H(+) + NADH + uridine(20b) in tRNA => 5,6-dihydrouridine(20b) in tRNA + NAD(+)


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Sus scrofa)


name: TGFBR3 binding to ARRB1/2 (Xenopus tropicalis)


name: WLS dissociates from retromer (Mus musculus)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Caenorhabditis elegans)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Homo sapiens)


name: Removal of miRNA passenger strand (Homo sapiens)


name: Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA (Homo sapiens)


name: OTUD7A hydrolyses K11diUb (Canis familiaris)


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)


name: 4-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase] => 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: UCKL1 phosphorylates urindine, cytidine (Saccharomyces cerevisiae)


name: SREBP1A,1C,2 binds Importin beta-1 (Sus scrofa)


name: MAPK6 is degraded by the 26S proteasome (Plasmodium falciparum)


name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) (Sus scrofa)


name: 3-(4-hydroxyphenyl)pyruvate + L-kynurenine = H2O + kynurenate + L-tyrosine


name: PTPN22 dissociates from CSK (Canis familiaris)


name: 5-HT2 receptor can bind serotonin (Danio rerio)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+) => beta-D-fructose 6-phosphate + GDP-alpha-D-mannose


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Sus scrofa)


name: hexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 9-hydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-phenylalanine + pyruvate <=> 3-phenylpyruvate + L-alanine


name: GSK3B phosphorylates p-NFE2L2 (Rattus norvegicus)


name: SALM1 binds NMDA receptor (Canis familiaris)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)


name: Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)


name: carboxynorspermidine + H2O + NADP(+) => H(+) + L-aspartate 4-semialdehyde + NADPH + propane-1,3-diamine


name: Interaction of integrin alphaVbeta3 with Tenascin (Canis familiaris)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O => (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 glutathione


name: ECE2 cleaves EDN1(53-90) (Xenopus tropicalis)


name: ALDH7A1 oxidises BETALD to BET (Homo sapiens)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Homo sapiens)


name: SFTPB,C, PC, PG translocate from lamellar body to extracellular region. (Gallus gallus)


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Canis familiaris)


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Rattus norvegicus)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADP(+) = 7,12-dioxo-lithocholate + H(+) + NADPH


name: 5-hydroxy-3-methyl-L-tyrosine + S-adenosyl-L-methionine = 5-hydroxy-3-methyl-O-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: Release of SEPT4 from mitochondria (Homo sapiens)


name: geranylgeranyl diphosphate = tuberculosinyl diphosphate


name: C5b:C6:C7 translocates to the plasma membrane (Sus scrofa)


name: H2O + sn-glycero-3-phospho-L-serine <=> H(+) + L-serine + sn-glycerol 3-phosphate


name: NPHP4 protein binds LATS proteins (Rattus norvegicus)


name: acetyl-CoA + S-benzyl-L-cysteine = CoA + H(+) + N-acetyl-S-benzyl-L-cysteine


name: alpha-D-glucose 1-phosphate + GDP-alpha-D-mannose => alpha-D-mannose 1-phosphate + GDP-alpha-D-glucose


name: 2 (S)-lactate(in) + prostaglandin E2(out) => 2 (S)-lactate(out) + prostaglandin E2(in)


name: ATP + diphosphate <=> ADP + H(+) + triphosphate


name: Proton-coupled histidine and di-peptide cotransport (Xenopus tropicalis)


name: USP9X (FAM) deubiquitinates SMAD4 (Drosophila melanogaster)


name: Budding of connexon-containing transport vesicles from the Golgi (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycero-3-phosphate + a fatty acid + H(+)


name: daidzein + O2 + reduced [NADPH--hemoprotein reductase] = 2'-hydroxydaidzein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TMEM55B translocates to the nucleus (Bos taurus)


name: STING binds TRIM32 or TRIM56  (Bos taurus)


name: AKT phosphorylates PHF20 (Rattus norvegicus)


name: a 3'-hydroxy,5'-unsubstituted flavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => a 3',5'-unsubstituted flavanone + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-oxohexanoate + L-glutamate => 2-oxoglutarate + L-2-aminohexanoate


name: 2-heptyl-4(1H)-quinolone + H(+) + NADH + O2 = 2-heptyl-3-hydroxy-4(1H)-quinolone + H2O + NAD(+)


name: Activated MET binds RANBP9 and SOS1 (Bos taurus)


name: Degradation multiubiquitinated Cyclin A (Bos taurus)


name: (E)-ferulate + UDP-alpha-D-glucose => 1-O-[(E)-feruloyl]-beta-D-glucose + UDP


name: TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 (Bos taurus)


name: 2'-deoxyadenosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + adenine


name: MSH2 variant:MSH3-defective DNA mismatch repair (Homo sapiens)


name: 2-phenylacetate + H(+) <=> CO2 + toluene


name: phosphate + pseudouridine => H2O + psi-UMP


name: succinate-semialdehyde dehydrogenase (NADP+) activity


name: ent-copalyl diphosphate synthase activity


name: [protein]-peptidylproline (omega=180) => [protein]-peptidylproline (omega=0)


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Canis familiaris)


name: Profilin:G-actin binds MKL1 (Sus scrofa)


name: 2 chloride(in) + oxalate(out) => 2 chloride(out) + oxalate(in)


name: EGFR phosphorylates NOTCH3 (Gallus gallus)


name: CHRM2 binds CHRM2 antagonists (Bos taurus)


name: ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE (Dictyostelium discoideum)


name: an (S)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H(+)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Dictyostelium discoideum)


name: 4 H(+) + uroporphyrinogen III => 4 CO2 + coproporphyrinogen III


name: Tankyrase ADP-ribosylates AXIN (Sus scrofa)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 <=> 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Danio rerio)


name: 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O <=> 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol


name: HGSNAT oligomer acetylates Heparan chain(1) (Rattus norvegicus)


name: a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)


name: PSGs bind proteoglycans and TGF-beta1 (Homo sapiens)


name: STAT3 is phosphorylated downstream of active ALK (Gallus gallus)


name: Formation of MSH2:MSH3 Complex (Canis familiaris)


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Sus scrofa)


name: p-S115 MAPKAPK5 translocates to the cytosol (Bos taurus)


name: Receptor CCR6 binds CCL20 ligand (Homo sapiens)


name: "arabinogalactan exo alpha-(1,3)-beta-L-arabinopyranosyl-(1->3)-L-arabinofuranosidase (non-reducing end)"


name: dimethylamine + L-citrulline => H2O + N(omega),N(omega)-dimethyl-L-arginine


name: SUMOylation of DAXX with SUMO1 (Xenopus tropicalis)


name: PDPK1 phosphorylates SGK1 (Dictyostelium discoideum)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Rattus norvegicus)


name: p-Y-STAT1,3,5 dimer translocates from the cytosol to the nucleoplasm (Homo sapiens)


name: HAO2 tetramer oxidises 2OH-PALM (Xenopus tropicalis)


name: C20 sphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (4R)-hydroxyeicosasphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: butan-2-one + hydrogen cyanide => 2-hydroxy-2-methylbutanenitrile


name: 4-acetamidobutanoate + H2O = 4-aminobutanoate + acetate


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Drosophila melanogaster)


name: PAAP-A proteolyzes IGF:IGFBP4 (Mus musculus)


name: 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-octadecyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: Part of pro-beta-NGF is processed to mature beta-NGF (Canis familiaris)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Homo sapiens)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(32-hydroxydotriacontanoyl)-sphing-4-enine = a diacylglycerol + N-(32-(9Z,12Z-octadecadienoyloxy)-dotricontanoyl)-sphing-4-enine


name: (3S)-hydroxyhexadecanedioyl-CoA => (2E)-hexadecenedioyl-CoA + H2O


name: methyl transfer-driven active transmembrane transporter activity


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Mus musculus)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Caenorhabditis elegans)


name: FZ and VANG bind to STAN homodimer (Drosophila melanogaster)


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Gallus gallus)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose <=> a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Bos taurus)


name: BPI binds LPS on the bacterial surface (Homo sapiens)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Bos taurus)


name: 15-oxoprostaglandin E2 + H(+) + NADPH => NADP(+) + prostaglandin E2


name: 3-oxosphinganine + hexadecanoyl-CoA = CoA + H(+) + N-hexadecanoyl-3-oxosphinganine


name: AUF1 (hnRNP D0) is ubiquitinylated (Mus musculus)


name: an N(2)-acyl-L-glutamine + H2O <=> a carboxylate + L-glutamine


name: C4b binding protein displaces C2a (Homo sapiens)


name: a dihydroceramide + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a phytoceramide + 2 Fe(III)-[cytochrome b5] + H2O


name: ATP + H2O + L-ornithine(out) <=> ADP + H(+) + L-ornithine(in) + phosphate


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Danio rerio)


name: A + H2O + progoitrin => AH2 + gluconapin + O2


name: 2 H(+) + O2 + p-xylene + 2 reduced [2Fe-2S]-[ferredoxin] => 4-methylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Sus scrofa)


name: 4-O-(beta-D-glucosyl)-(E)-coniferol + H2O => (E)-coniferol + D-glucose


name: 2-hydroxyglutarate + FAD + H(+) = 2-oxoglutarate + FADH2


name: CBX4 SUMOylates BMI1 in PRC1 with SUMO1 (Bos taurus)


name: 2 AH2 + all-trans-4,4'-diapolycopene-4,4'-dioate + 2 H(+) => 2 A + all-trans-4,4'-diapolycopene-4,4'-dial + 2 H2O


name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Drosophila melanogaster)


name: D-sedoheptulose 7-phosphate <=> 2-epi-valiolone + phosphate


name: Tenascins C, R, (X, N) bind fibronectin matrix (Xenopus tropicalis)


name: H(+) + IDP + N-acetyl-D-glucosamine 6-phosphate => ITP + N-acetyl-D-glucosamine


name: trans-4-hydroxy-L-proline betaine <=> cis-4-hydroxy-D-proline betaine


name: Rev multimer-bound HIV mRNA associates with Crm1 (Homo sapiens)


name: erinacine Q2 + H(+) + UDP => 11-O-acetylcyathatriol + UDP-alpha-D-glucose


name: Release of activated MAD2 from kinetochores (Homo sapiens)


name: Formation of eIF2:GDP:eIF2B intermediate (Gallus gallus)


name: 2-oxospirilloxanthin + H2O => 2,2-dihydroxyspirilloxanthin


name: chlorophyllide a + NADP(+) => 3,8-divinyl chlorophyllide a + H(+) + NADPH


name: CO2 + 2 H2O + heme b => H(+) + H2O2 + harderoheme III


name: CYP19A1 hydroxylates ANDST to E1 (Sus scrofa)


name: G alpha (q) in G (q):RGS complex is inactivated (Sus scrofa)


name: Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants (Homo sapiens)


name: EDTA + FMNH2 + O2 => ethylenediaminetriacetate + FMN + glyoxylate + 2 H(+) + H2O


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Drosophila melanogaster)


name: "D-arabinan exo alpha-(1,3)/(1,5)-arabinofuranosidase (non-reducing end)"


name: Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)


name: H(+)(out) + L-lysine(out) <=> H(+)(in) + L-lysine(in)


name: Expression of Acetyl CoA Carboxylase 2 (ACACB, ACC2) (Homo sapiens)


name: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O => (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H(+)


name: Formation of hRSV A dsRNA intermediate form (Homo sapiens)


name: CTNNB1:TCF7L2,LEF1 binds the CCND1 gene promoter (Homo sapiens)


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Gallus gallus)


name: TRMT13 2'-O-methylates adenosine-4 in tRNA (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 3-acyl-sn-glycerol = a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Homo sapiens)


name: Conversion of glyoxylate to oxalate (Rattus norvegicus)


name: RB1 recruits APC/C:Cdh1 complex to SKP2 (Homo sapiens)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Homo sapiens)


name: 2 1-(9Z-octadecenoyl)-glycerol <=> 1,2-di-(9Z-octadecenoyl)-glycerol + glycerol


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)


name: Glutamine transport from astrocytes (Saccharomyces cerevisiae)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Dictyostelium discoideum)


name: PTPN11 binds p-Y759-IL6ST (Rattus norvegicus)


name: AH2 + androst-4-ene-3,17-dione + O2 => A + H2O + testololactone


name: RUNX3 binds SRC (Caenorhabditis elegans)


name: cyclobis-(1->3)-alpha-D-isomaltosyl + H2O <=> alpha-isomaltosyl-(1->3)-isomaltose


name: 1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MAPKAPK5 phosphorylates KALRN (Gallus gallus)


name: Neuroglobin binds oxygen (Gallus gallus)


name: p-4Y-PLCG1 dissociates from activated FGFR3 (Homo sapiens)


name: alpha-secretase cleaves the p75NTR extracellular domain (Sus scrofa)


name: Formation of the PINCH-ILK-parvin complex (Bos taurus)


name: LEF1 binds the promoter of the CEBPA gene (Homo sapiens)


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Bos taurus)


name: H(+) + NADH + O2 + orcinol => 2,3,5-trihydroxytoluene + H2O + NAD(+)


name: Galanin receptors can bind galanin (Homo sapiens)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Gallus gallus)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Rattus norvegicus)


name: L-cysteine + S-sulfanyl-L-cysteine => L-alanine + S-disulfanyl-L-cysteine


name: luteolin + S-adenosyl-L-methionine <=> H(+) + luteolin 7-methyl ether + S-adenosyl-L-homocysteine


name: a 2-oxocarboxylate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid


name: Formation of the Flap Intermediate on the C-strand (Bos taurus)


name: 4-(trifluoromethyl)benzaldehyde + H(+) + NADH => 4-(trifluoromethyl)benzyl alcohol + NAD(+)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycerol + H(+)


name: TRAF1 binds TRAF2 within TNFR1 signaling complex (Homo sapiens)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Sus scrofa)


name: atRAL binds to RBP2 (Xenopus tropicalis)


name: GLI1 is degraded by the proteasome after ubiquitination by ITCH (Homo sapiens)


name: an N-(2-hydroxyacyl)-sphinganine + UDP-alpha-D-galactose => an N-(2-hydroxyacyl)-beta-D-galactosyl-sphinganine + H(+) + UDP


name: GNLY binds the bacterial cell surface in the phagosome (Canis familiaris)


name: amino acid:monoatomic cation antiporter activity


name: RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)


name: LGALS3 gene expression is stimulated by RUNX1 and RUNX2 (Homo sapiens)


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Rattus norvegicus)


name: cGMP-stimulated cyclic-nucleotide phosphodiesterase activity


name: asperlicin C + H(+) + NADPH + O2 = asperlicin E + H2O + NADP(+)


name: DEK binds TFAP2A homodimers (Drosophila melanogaster)


name: H(+) + UDP-alpha-D-glucuronate => CO2 + UDP-alpha-D-xylose


name: an anilide + H2O => a carboxylate + aniline + H(+)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + cholesterol = 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z,12Z)-octadecadienoate


name: ABCC1 transports cytosolic RCbl to extracellular region (Dictyostelium discoideum)


name: 1,4-benzoquinone + H(+) + NADH <=> hydroquinone + NAD(+)


name: (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone A


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA <=> an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + holo-[ACP]


name: 2-demethylmenaquinone-8 + H(+) + NADPH <=> 2-demethylmenaquinol-8 + NADP(+)


name: dihydroxyacetone phosphate + L-glutamate = (S)-serinol phosphate + 2-oxoglutarate


name: CYP17A1 cleaves 17aHPREG to DHA (Sus scrofa)


name: (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein] => (9Z,12Z)-octadecadienoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: 2 H(+) + hexanoyl-CoA + 2 malonyl-CoA => 4-hydroxy-6-pentylpyran-2-one + 2 CO2 + 3 CoA


name: ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Canis familiaris)


name: CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Drosophila melanogaster)


name: H2O + NAD(+) + perillyl aldehyde <=> 2 H(+) + NADH + perillate


name: (E)-caffeate + H(+) + shikimate => 5-O-[(E)-caffeoyl]-shikimate + H2O


name: MYLK (MLCK) Active Calmodulin Binding (Sus scrofa)


name: PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Rattus norvegicus)


name: 2'-O-methyluridine(1369) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(1369) in 16S rRNA


name: 4-O-deacetylvindoline + CO2 + succinate => 2-oxoglutarate + deacetoxyvindoline + O2


name: 3-oxochenodeoxycholate + H(+) + NADH <=> isochenodeoxycholate + NAD(+)


name: Hydrolysis of PIP3 to PI(3,4)P2 (Bos taurus)


name: a sphingomyelin(in) + ATP + H2O <=> a sphingomyelin(out) + ADP + H(+) + phosphate


name: XPO1 binds the beta-catenin:CBY complex (Rattus norvegicus)


name: NTRK2-phosphorylated FRS2 binds GRB2 (Bos taurus)


name: carnosine(out) + H(+)(out) => carnosine(in) + H(+)(in)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Danio rerio)


name: ITCH polyubiquitinates TP73 (Homo sapiens)


name: Removal of fibrillar collagen N-propeptides (Canis familiaris)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Mus musculus)


name: deoxyviolaceinate + H(+) + O2 = CO2 + deoxyviolacein + H2O


name: 2 H(+)(in) + N-formyl-L-methionyl-L-leucyl-L-phenylalanine(in) => 2 H(+)(out) + N-formyl-L-methionyl-L-leucyl-L-phenylalanine(out)


name: ALDH3B1 oxidises HXAL to PALM (Saccharomyces cerevisiae)


name: H2O + L-dehydroascorbate <=> 2,3-dioxo-L-gulonate


name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate (Homo sapiens)


name: L1 interaction with Integrins (Xenopus tropicalis)


name: (13E)-labda-7,13-dien-15-yl diphosphate => diphosphate + labda-7,13(16),14-triene


name: (11Z)-eicosenoate + (4R)-hydroxysphinganine => H2O + N-(11Z-eicosenoyl)-(4R)-hydroxysphinganine


name: (2E,6E)-farnesyl diphosphate = (-)-beta-barbatene + diphosphate


name: AFG3L2 binds mitochondrial inner membrane proteins (Rattus norvegicus)


name: CatSper Channel Mediated Calcium Transport (Sus scrofa)


name: Aquaporins passively transport glycerol into cells (Xenopus tropicalis)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Homo sapiens)


name: ABCAs mediate lipid influx (Dictyostelium discoideum)


name: Release of p-STAT2:p-STAT1 dimer (Gallus gallus)


name: 1,4-benzoquinone + H(+) + NADPH => hydroquinone + NADP(+)


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Canis familiaris)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Sus scrofa)


name: Formation of fatty acid synthase (FAS) dimer (Rattus norvegicus)


name: O-GlcNAcylation of RIPK3 (TLR4 signaling) (Homo sapiens)


name: Mature NOTCH heterodimer traffics to the plasma membrane (Homo sapiens)


name: Phosphorylation of RAD51 by tyrosine kinase Abelson family protein members (Gallus gallus)


name: p‑Y705-STAT3 dissociates from IL19:IL20RA:p-JAK1:IL20RB (Rattus norvegicus)


name: nsp12 misincorporates a nucleotide in nascent RNA minus strand (Homo sapiens)


name: 2-oxoglutarate + L-ectoine + O2 = 5-hydroxyectoine + CO2 + succinate


name: Thr-180 of ULK1 is phosphorylated (Canis familiaris)


name: Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants (Homo sapiens)


name: PCho is dephosphorylated to Cho by PHOSPHO1 (Homo sapiens)


name: 2-oxopropyl-coenzyme M + H(+) + NADH => (S)-2-hydroxypropyl-coenzyme M + NAD(+)


name: Formation of MCM2-7 complex (Gallus gallus)


name: PXLP-K56-SRR dimer deaminates L-Ser (Schizosaccharomyces pombe)


name: alpha-L-arabinopyanose + NADP(+) = H(+) + L-arabinono-1,4-lactone + NADPH


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Rattus norvegicus)


name: Dopachrome is transformed to DHICA by DCT (Sus scrofa)


name: Passive I- efflux mediated by SLC5A8 (Rattus norvegicus)


name: nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical  HDL + chylomicron (Mus musculus)


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + H2O = 1D-myo-inositol 2,3,4,5-tetrakisphosphate + phosphate


name: Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Homo sapiens)


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Mus musculus)


name: H2O + UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose <=> 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + H(+) + UDP


name: Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Bos taurus)


name: ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A <=> ADP + H(+) + lipid A-core


name: double-stranded DNA exodeoxyribonuclease activity


name: hydrogen cyanide + piperonal => (2S)-2-(2H-1,3-benzodioxol-5-yl)-2-hydroxyacetonitrile


name: JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Xenopus tropicalis)


name: H(+) + L-dopa + NADH <=> 3-(3,4-dihydroxyphenyl)propanoate + NAD(+) + NH4(+)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Sus scrofa)


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Dictyostelium discoideum)


name: CYP4F8 19-hydroxylates PGH2 (Homo sapiens)


name: 1-acyl LPS is acylated to PS by LPSAT (Drosophila melanogaster)


name: UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Homo sapiens)


name: Activated MAPK phosphorylates RAF1 (Caenorhabditis elegans)


name: PIAS4 SUMOylates RNF168 with SUMO1 (Rattus norvegicus)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)


name: Truncated Alpha-1-Microglobulin binds heme (Sus scrofa)


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Sus scrofa)


name: diphosphate + menaquinol-4 => (2E,6E,10E)-geranylgeranyl diphosphate + menadiol


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Xenopus tropicalis)


name: ZFP36 (TTP) recruits RNA degradation activities (Homo sapiens)


name: 16,17-didehydroprogesterone + H2O => 16alpha-hydroxyprogesterone


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Rattus norvegicus)


name: TGFBR2 phosphorylates TGFBR1 (Caenorhabditis elegans)


name: [sulfur carrier]-SH + AH2 + N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine <=> 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: (2E,6E)-farnesyl diphosphate <=> delta-cadinene + diphosphate


name: (2E,6E)-farnesyl diphosphate = (-)-delta-cadinene + diphosphate


name: SLC9B2 exchanges Na+ for H+ (Xenopus tropicalis)


name: glutathione + H(+) + succinate => H2O + S-succinylglutathione


name: a nucleoside 5'-phosphate + H2O => a nucleoside + phosphate


name: Transfer of Ub from E2 to substrate and release of E2 (Saccharomyces cerevisiae)


name: (+)-isomalbrancheamide B + bromide + FAD + 2 H(+) = (+)-isomalbrancheamide D + FADH2


name: SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Caenorhabditis elegans)


name: p-T68-CHEK2 dimerizes (Schizosaccharomyces pombe)


name: CDSN binds the cornified envelope (Rattus norvegicus)


name: Recruitment of POLB to oxidatively damaged AP site (Bos taurus)


name: CDC42 GEFs activate CDC42 (Canis familiaris)


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine <=> 1,3,3'-tri-O-methyl-4alpha-mannobiose + H(+) + S-adenosyl-L-homocysteine


name: ATP + citrate + L-glutamate = ADP + beta-citrylglutamate + H(+) + phosphate


name: (9Z,12Z)-octadecadienamide + H2O <=> (9Z,12Z)-octadecadienoate + NH4(+)


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Xenopus tropicalis)


name: a hydroperoxide + H(+) + NADH = an alcohol + H2O + NAD(+)


name: Initial activation of proMMP13 by plasmin and trypsin (Bos taurus)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Gallus gallus)


name: N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyl,N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-homocysteine


name: (5S,9S,10S)-drim-7-en-11-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> (5S,10S)-(9R)-7-drimene-11,12-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SCF-beta-TrCP ubiquitinylates IkB (Homo sapiens)


name: RHOQ binds effectors at the plasma membrane (Rattus norvegicus)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Mus musculus)


name: 3-(2-aminophenyl)-3-oxopropanal = H2O + quinolin-4-ol


name: NRF1:PPARGC1B binds the ALAS1 promoter (Homo sapiens)


name: GBF1 recruits ARF:GDP to the ERGIC (Canis familiaris)


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O => 6-phospho-D-gluconate


name: a 3'-end ribonucleotide-RNA + a ribonucleoside 5'-phosphate + H(+) => a 3'-end ribonucleotidyl-ribonucleotide-RNA + H2O


name: 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine <=> 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + H(+) + S-adenosyl-L-homocysteine


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Rattus norvegicus)


name: (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 <=> (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Mus musculus)


name: Activated NOD2 oligomerizes (Dictyostelium discoideum)


name: HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Sus scrofa)


name: (3S,5S)-carbapenam-3-caboxylate + 2-oxoglutarate + O2 = (5R)-carbapenem-3-carboxylate + CO2 + H2O + succinate


name: acetyl-CoA + N-terminal L-threonyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-threonyl-[protein]


name: Recruitment Of Cytoplasmic Proteins To Vesicles (Canis familiaris)


name: Dopamine synaptic vesicle docking and priming (Mus musculus)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Dictyostelium discoideum)


name: Cleavage of hypoxanthine by MPG glycosylase (Gallus gallus)


name: (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O <=> 2-dehydro-3-deoxy-D-gluconate + NH4(+)


name: H2O + L,L-cystathionine => 2-oxobutanoate + L-cysteine + NH4(+)


name: a 2-acyl-sn-glycerol 3-phosphate + choline + H(+) => a 2-acyl-sn-glycero-3-phosphocholine + H2O


name: 5-methyltetrahydrosarcinapterin + coenzyme M + 2 Na(+)(in) = 5,6,7,8-tetrahydrosarcinapterin + methyl-coenzyme M + 2 Na(+)(out)


name: CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Mus musculus)


name: Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind GRB2:GAB1 (Homo sapiens)


name: IL6ST is tyrosine phosphorylated (Mus musculus)


name: H(+) + NADPH + prostaglandin H2 => NADP(+) + prostaglandin F2alpha


name: methanofuran + N(5)-formyl-5,6,7,8-tetrahydromethanopterin => 5,6,7,8-tetrahydromethanopterin + H(+) + N-formylmethanofuran


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Schizosaccharomyces pombe)


name: a ubiquinol + CO2 => a ubiquinone + formate + H(+)


name: (2E)-octenal + H2O + NAD(+) = (2E)-octenoate + 2 H(+) + NADH


name: CoA + H(+) + N(alpha)-acetyl-L-methionine => acetyl-CoA + L-methionine


name: MMP14:TIMP2 binds proMMP2 (Rattus norvegicus)


name: odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Homo sapiens)


name: an acyl-CoA + zymosterol => CoA + zymosterol ester


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Sus scrofa)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Caenorhabditis elegans)


name: 3-hydroxypentacecilide A + A <=> AH2 + chrodrimanin C


name: D-mannose 6-phosphate + H2O + phosphoenolpyruvate <=> 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate


name: Recruitment of VAV1 to p-6Y-SYK (Bos taurus)


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Rattus norvegicus)


name: Hh C-terminal fragments are degraded by the proteasome (Homo sapiens)


name: diphosphate + IC-asc-C7-AMP => ATP + H(+) + IC-asc-C7


name: beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + H2O = beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + lactose


name: RASA1 stimulates RAS GTPase activity (Drosophila melanogaster)


name: CoA + thiomarinol C => holothin + marinoloyl-CoA C


name: PRKCI phosphorylates NFE2L2 (Danio rerio)


name: dodecanoyl-CoA + H(+) + L-serine = 3-oxotetradecasphinganine + CO2 + CoA


name: NOTCH1 stimulates HES1 transcription (Homo sapiens)


name: formaldehyde + H2O + N-methyl-L-proline + NADP(+) => H(+) + L-proline betaine + NADPH + O2


name: TP53 stimulates IGFBP3 expression (Homo sapiens)


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Gallus gallus)


name: acrylate + H(+) + NADH <=> NAD(+) + propanoate


name: diphosphate + Fe(II)-heme o => (2E,6E)-farnesyl diphosphate + H2O + heme b


name: PTPN3 dephosphorylates EPS15 (Bos taurus)


name: ADRM1 binds 26S proteasome (Plasmodium falciparum)


name: agmatine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + N(1)-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine


name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Sus scrofa)


name: (R)-carnitine(in) + ADP + H(+) + phosphate => (R)-carnitine(out) + ATP + H2O


name: Phosphorylation of Syntaxin-4 (Rattus norvegicus)


name: Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphate + H(+) + hexadecanoate


name: a 1-acyl-sn-glycerol + H2O <=> a fatty acid + glycerol + H(+)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Saccharomyces cerevisiae)


name: FAD + H(+) + heptadecanoyl-CoA = FADH2 + trans-2-heptadecenoyl-CoA


name: cholesteryl (9Z-octadecenoate) + H2O = (9Z)-octadecenoate + cholesterol + H(+)


name: chlorophyllide a + H(+) + NADPH + O2 = 7(1)-hydroxychlorophyllide a + H2O + NADP(+)


name: (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate => (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate


name: 3-oxooctanoyl-[ACP] + CO2 + CoA => H(+) + hexanoyl-CoA + malonyl-[ACP]


name: RAC1 translocates to the endoplasmic reticulum membrane (Canis familiaris)


name: 6 (S)-methylmalonyl-CoA + 12 H(+) + malonyl-CoA + 5 NADPH <=> 7 CO2 + 7 CoA + 2 H2O + 5 NADP(+) + narbonolide


name: Recruitment of Grb2 to pFAK:NCAM1 (Rattus norvegicus)


name: CDC42 GDIs block activation of CDC42 (Sus scrofa)


name: (R)-2-hydroxy-fatty acid dehydrogenase activity


name: H(+)(out) + N,N-dimethylglycine(out) => H(+)(in) + N,N-dimethylglycine(in)


name: IGF1R phosphorylates SHC1 (Rattus norvegicus)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Mus musculus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: JAK2 phosphorylates STAT1/STAT3 (Homo sapiens)


name: Nectin-1:Nectin-4 trans heterodimer formation (Bos taurus)


name: LUBAC ubiquitinates RIPK1 at K627 (Homo sapiens)


name: 2-oxoglutarate + gibberellin A19 + O2 <=> CO2 + gibberellin A17 + H(+) + succinate


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Mus musculus)


name: Resumption of elongation after recovery from pausing (Drosophila melanogaster)


name: 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) (Homo sapiens)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Homo sapiens)


name: EET(1) is hydrolysed to DHET(1) by EPHX2 (Xenopus tropicalis)


name: Fe-coproporphyrin III + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + 2 CO2 + heme b + 2 L-methionine


name: SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 (Bos taurus)


name: Translocation of PLC-gamma1 to PIP2 (Rattus norvegicus)


name: 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H2O <=> alpha-D-glucose 1-phosphate + alpha-D-mannose derivative + H(+)


name: Interaction of ABL with ROBO1:SLIT2 (Mus musculus)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Gallus gallus)


name: GalNAc is transferred onto 3a (Homo sapiens)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Bos taurus)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Bos taurus)


name: STAT3 binds activated MET receptor (Sus scrofa)


name: 2-dehydro-3-deoxy-L-arabinonate + H2O => L-lyxonate


name: ACAD11 dehydrogenates BH-CoA (Danio rerio)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: 7-oxopregnenolone + H(+) + NADPH <=> 7beta-hydroxypregnenolone + NADP(+)


name: Terminal (3' end) cleavage of viral DNA (Homo sapiens)


name: HS-GAGs translocate to the lysosome for degradation (Mus musculus)


name: a ganglioside GT1b + CMP + H(+) => a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate


name: LDL + LDLR => LDL:LDLR complex (Mus musculus)


name: beta-D-Gal-(1<->1')-Cer + UDP-alpha-D-galactose => alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer + H(+) + UDP


name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Canis familiaris)


name: Thrombin, ELANE cleave C5 (Canis familiaris)


name: Aquaporins passively transport glycerol out of cells (Sus scrofa)


name: 7-epi-alpha-eudesmol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: LDLR is bound by DAB2 and ARH (Rattus norvegicus)


name: (1S,4R)-1-hydroxylimonen-2-one + NADPH + O2 <=> (3R)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Rattus norvegicus)


name: ATP + H(+) + L-glutamate <=> diphosphate + L-glutamyl-5'-AMP


name: a polyvinyl alcohol + n O2 => an oxidized polyvinyl alcohol + n H2O2


name: 2-demethylmenaquinol-6 + S-adenosyl-L-methionine <=> H(+) + menaquinol-6 + S-adenosyl-L-homocysteine


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Gallus gallus)


name: glycodeoxycholate(out) + 2 Na(+)(out) => glycodeoxycholate(in) + 2 Na(+)(in)


name: Interleukin-1 family precursors are cleaved by caspase-1 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate => (+)-beta-chamigrene + diphosphate


name: 3-oxochol-4-en-22-oate + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochol-4-en-22-oate + H2O + NAD(+)


name: ATP + H2O + selenate(out) = ADP + H(+) + phosphate + selenate(in)