name: L-lysyl-[protein] + propanoyl-CoA = CoA + H(+) + N(6)-propanoyl-L-lysyl-[protein]


name: 13-(2-methylcrotonoyloxy)lupanine + CoA => (2E)-2-methylbut-2-enoyl-CoA + 13-hydroxylupanine


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Homo sapiens)


name: AMP + 2 H(+) + phenyl phosphate + phosphate => ATP + H2O + phenol


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(36-hydroxyhexatriacontadienoyl)-sphing-4-enine => a diacylglycerol + an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontadienoyl)-sphing-4-enine


name: 5,6-dihydrouracil + NADP(+) = H(+) + NADPH + uracil


name: SMURF1/2 dissociates from ub-PTCH1 (Mus musculus)


name: peptide-methionine (S)-S-oxide reductase activity


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Xenopus tropicalis)


name: Interleukin-1 receptor type 2 binds Interleukin 1 (Sus scrofa)


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Mus musculus)


name: PAK1 or PAK2 phosphorylates MYLK (Sus scrofa)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Homo sapiens)


name: ATP + CoA + hexacosanoate = AMP + diphosphate + hexacosanoyl-CoA


name: NCEH1 hydrolyzes cholesterol esters (Bos taurus)


name: Splicing of HIV RNA transcript (Homo sapiens)


name: ACSF2 ligates CoA-SH to MCFA (Mus musculus)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 => (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate


name: JAK1-mediated phosphorylation of RAF1 (Rattus norvegicus)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Sus scrofa)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Plasmodium falciparum)


name: (15Z)-tetracosenamide + H2O => (15Z)-tetracosenoate + NH4(+)


name: SREBP1A,1C,2:Importin beta-1 dissociates (Sus scrofa)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Canis familiaris)


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Sus scrofa)


name: CTLH E3 ligase ubiquitinates PKM-1 (Dictyostelium discoideum)


name: L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[NO transferase protein] <=> L-cysteinyl-[NO transferase protein] + S-nitroso-L-cysteinyl-[protein]


name: Phosphorylation of Chk1 by ATM upon DNA damage (Gallus gallus)


name: UCHL5 binds INO80 complex (Canis familiaris)


name: RRAGA,B hydrolyzes GTP (Rattus norvegicus)


name: PTK6 phosphorylates SFPQ (Caenorhabditis elegans)


name: (3R)-hydroxybutanoate tetramer + H2O = (3R)-hydroxybutanoate trimer + (R)-3-hydroxybutanoate + H(+)


name: Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) (Bos taurus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + malonyl-CoA <=> (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA + CO2 + CoA


name: chenodeoxycholoyl-CoA + glycine = CoA + glycochenodeoxycholate + H(+)


name: BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)


name: PTPN3 binds p-T183,Y185 MAPK12 (Sus scrofa)


name: NADPH + 2 O2 + prefumagillin <=> acetaldehyde + fumagillin + H2O + NADP(+)


name: STING binds c-di-GMP (Xenopus tropicalis)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Homo sapiens)


name: L-glutamate + sulfoacetaldehyde => 2-oxoglutarate + taurine


name: a sphingomyelin(out) => a sphingomyelin(in)


name: THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Dictyostelium discoideum)


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Danio rerio)


name: H2O + N(omega)-(ADP-D-ribosyl)-L-arginine => ADP-D-ribose + L-arginine


name: NOTCH4 gene transcription is inhibited by RUNX1 (Homo sapiens)


name: Ubiquitinated Orc1 is degraded by the proteasome (Homo sapiens)


name: p-Y705-STAT3 binds p-Y693-STAT4 (Caenorhabditis elegans)


name: RAB33B:GTP binds RIC1:RGP1 (Xenopus tropicalis)


name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Drosophila melanogaster)


name: Caspase-mediated cleavage of occludin (Caenorhabditis elegans)


name: a 1,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol


name: (R)-carnitine + 3-hydroxybutanoyl-CoA <=> CoA + O-3-hydroxybutanoyl-(R)-carnitine


name: THTPA:Mg2+ hydrolyzes ThTP to TDP (Bos taurus)


name: Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions (Bos taurus)


name: lactate + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate


name: Prolysyl oxidase activation (Homo sapiens)


name: Canonical WNT signaling through the atypical receptor RYK (Rattus norvegicus)


name: histone H3K4 dimethyltransferase activity


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)


name: DT A:B binds HBEGF and CD9 on the target cell surface (Homo sapiens)


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Homo sapiens)


name: ACSM2B-like proteins transform ST to ST-CoA (Danio rerio)


name: Interaction of Bcl10 to CARMA1 (Bos taurus)


name: (9Z)-octadecenoate + 13-hydroxy-octadecanoate + H(+) => 13-(9Z-octadecenoyloxy)-octadecanoate + H2O


name: PDE4A hydrolyses cAMP to AMP (Drosophila melanogaster)


name: 2-acyl LPC is acylated to PC by LPCAT (Canis familiaris)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Canis familiaris)


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Bos taurus)


name: HDAC3 containing complexes deacetylate histone (Homo sapiens)


name: Metallochaperone inserts 2Cu2+ into MT-CO2 (Sus scrofa)


name: erythromycin B + H(+) + S-adenosyl-L-homocysteine => erythromycin D + S-adenosyl-L-methionine


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Xenopus tropicalis)


name: (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] => (S)-corytuberine + 2 H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated FGFR4 phosphorylates FRS2 (Caenorhabditis elegans)


name: FOXA1 and GATA3 bind to CCND1 promoter (Canis familiaris)


name: D-serine + H2O + NAD(+) <=> 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Bos taurus)


name: Dimerized phospho-IRF3 migrates to the nucleus (Rattus norvegicus)


name: USP34 deubiquitinates AXIN1,AXIN2 (Mus musculus)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Drosophila melanogaster)


name: Exocytosis of platelet alpha granule contents (Mus musculus)


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Canis familiaris)


name: dsDNA:AIM2:ASC cluster binds procaspase-1 (Homo sapiens)


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Danio rerio)


name: 5-oxo-L-proline + butirosin B => gamma-L-glutamyl-butirosin B


name: Dissociation of insulin from insulin receptor (Bos taurus)


name: Gelatin degradation by MMP19 (Homo sapiens)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Rattus norvegicus)


name: 2-dehydro-D-gluconate + NADP(+) <=> 2,5-didehydro-D-gluconate + H(+) + NADPH


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1,2-dihexadecanoyl-sn-glycerol + H(+) + phosphocholine


name: MSTN gene expression is stimulated by FOXO1 and p-2S-SMAD2/3:SMAD4 (Homo sapiens)


name: (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + H(+) + oxidized [electron-transfer flavoprotein] + sarcosine = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + glycine + reduced [electron-transfer flavoprotein]


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Homo sapiens)


name: Activated FGFR3:p-FRS bind to PPTN11 (Gallus gallus)


name: RAS mutants bind inactive RAF (Homo sapiens)


name: 3'-ketolactose + H2O => 3-keto-beta-D-galactose + beta-D-glucose


name: D-sorbitol 6-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH


name: fumarate + L-arginine => 2-(N(omega)-L-arginino)succinate


name: HNP1-4 are stored in primary neutrophil granules (Rattus norvegicus)


name: GNRHR binds GNRHR peptide antagonists (Rattus norvegicus)


name: Caspase cleavage of DCC (Drosophila melanogaster)


name: H(+) + xanthine-8-carboxylate => pteridine-2,4,6,7-tetrol


name: PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 (Homo sapiens)


name: DAG stimulates protein kinase C-delta (Schizosaccharomyces pombe)


name: atRAL can spontaneously react with PE to form NRPE (Homo sapiens)


name: Association of procollagen type XXI (Rattus norvegicus)


name: NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + H2O + heme b => diphosphate + Fe(II)-heme o


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Mus musculus)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Rattus norvegicus)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Drosophila melanogaster)


name: Ligand-independent dimerization of PDGFR mutants (Homo sapiens)


name: a 4,5-saturated-(2E)-enoyl-CoA + NADP(+) = a (2E,4E)-dienoyl-CoA + H(+) + NADPH


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Drosophila melanogaster)


name: 2 hydroxylamine + 2 NAD(+) => 2 H(+) + hyponitrous acid + 2 NADH


name: (2Z,6Z)-farnesyl diphosphate <=> beta-bisabolene + diphosphate


name: RAN stimulates fusion of nuclear envelope (NE) membranes (Mus musculus)


name: 2 Na(+)(out) + taurodeoxycholate(out) = 2 Na(+)(in) + taurodeoxycholate(in)


name: 3-isopropenyl-6-oxoheptanoate + H(+) => 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one


name: Beta-catenin recruits CDC73 and LEO1 (Bos taurus)


name: CYP2F1 dehydrogenates 3-methylindole (Dictyostelium discoideum)


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Schizosaccharomyces pombe)


name: a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Caenorhabditis elegans)


name: SLC6A4 binds TCAs and SSRIs (Plasmodium falciparum)


name: 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + ATP + CoA = 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: Factor B binds to C3(H2O) (Xenopus tropicalis)


name: K63polyUb-TAK1 autophosphorylates (Gallus gallus)


name: PIAS4 SUMOylates HERC2 with SUMO1 (Rattus norvegicus)


name: E1 mediated ubiquitin activation (Schizosaccharomyces pombe)


name: Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Mus musculus)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Danio rerio)


name: DFF dissociates from importin-alpha:importin-beta (Xenopus tropicalis)


name: A + all-trans-zeta-carotene = AH2 + all-trans-neurosporene


name: ADRB2 in ADRB2:GRK complex is phosphorylated (Rattus norvegicus)


name: (R)-carnitine + crotonobetainyl-CoA => (R)-carnitinyl-CoA + crotonobetaine


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Homo sapiens)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Canis familiaris)


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Homo sapiens)


name: MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex (Homo sapiens)


name: SFTPs translocate from extracellular region to clathrin-coated vesicle (Canis familiaris)


name: chenodeoxycholate + lithocholoyl-CoA <=> chenodeoxycholoyl-CoA + lithocholate


name: SLC36A1-mediated uptake of glycine, proline, and alanine (Caenorhabditis elegans)


name: beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O <=> chenodeoxycholate + D-glucose


name: ATM binds PEX5 (Dictyostelium discoideum)


name: 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP] => (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP]


name: calciol + O2 + reduced [NADPH--hemoprotein reductase] = calcidiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Inner coat assembly and cargo binding (Mus musculus)


name: H2O + N(6)-acyl-L-lysyl-[protein] + NAD(+) => 2''-O-acyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: 3 Na(+)(out) + phosphate(out) => 3 Na(+)(in) + phosphate(in)


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Homo sapiens)


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Canis familiaris)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O => a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine


name: 2 chloride(out) + hydrogencarbonate(in) = 2 chloride(in) + hydrogencarbonate(out)


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)


name: 13-cis-retinol + a fatty acyl-CoA <=> 13-cis-retinyl ester + CoA


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Gallus gallus)


name: 16-epivellosimine + acetyl-CoA = CoA + vinorine


name: 3-aminopropanal + H2O2 + NH4(+) => H2O + O2 + propane-1,3-diamine


name: 2-oxoglutarate + a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + O2 => a 5'-end triphospho-guanosine-ribonucleotide-snRNA + CO2 + formaldehyde + H(+) + succinate


name: H(+) + indole-3-pyruvate + NADH + NH4(+) => H2O + L-tryptophan + NAD(+)


name: Phosphorylation and activation of CHEK2 by ATM (Homo sapiens)


name: 3',4',5,7-tetrahydroxy-3-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => quercetin + S-adenosyl-L-methionine


name: Clathrin internalises EPH:EFN complexes (Canis familiaris)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => (9Z)-octadecenoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-hexacosanoylsphinganine = a 1,2-diacyl-sn-glycerol + N-(hexacosanoyl)-sphinganine-1-(1D-myo-inositol)


name: 2-oxoglutarate + L-glutamate + O2 = (3R)-3-hydroxy-L-glutamate + CO2 + succinate


name: IL21 receptor STAT phosphorylation (Gallus gallus)


name: 5-HT2 receptor can bind serotonin (Gallus gallus)


name: L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: ATP6AP1 binds V-ATPase (Xenopus tropicalis)


name: 3-dehydro-D-glucose + D-glucose => 3-dehydro-alpha,alpha-trehalose + H2O


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Rattus norvegicus)


name: DCXR tetramer reduces L-xylulose to xylitol (Canis familiaris)


name: receptor serine/threonine kinase binding


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Mus musculus)


name: TNF-alpha inhibitors bind to TNF(1-233) trimer (Bos taurus)


name: MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Canis familiaris)


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Rattus norvegicus)


name: 5,6-dihydrouridine(47) in tRNA + NADP(+) = H(+) + NADPH + uridine(47) in tRNA


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 8-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5 H(+) + 3 O2 + obtusifoliol + 6 reduced [2Fe-2S]-[ferredoxin] <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: 4-methylumbelliferone + acetate + H(+) => 4-methylumbelliferyl acetate + H2O


name: ATM phosphorylates WHSC1 (Rattus norvegicus)


name: (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + CO2 + CoA


name: ATP + D-alanine + holo-[D-alanyl-carrier protein] <=> AMP + D-alanyl-[D-alanyl-carrier protein] + diphosphate


name: An atROL isomerase isomerises atROL to 11cROL (Homo sapiens)


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Danio rerio)


name: 1-deoxy-D-xylulose + ATP => 1-deoxy-D-xylulose 5-phosphate + ADP + H(+)


name: ABCG4 may mediate cholesterol efflux (Rattus norvegicus)


name: D-glyceraldehyde + H(+) + NADH <=> glycerol + NAD(+)


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Danio rerio)


name: Formation of the PCAF-ATAC complex (Rattus norvegicus)


name: IL1F10(?-152) binds IL1RAPL1 (Homo sapiens)


name: a (9Z,12E)-hexadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (9Z)-hexadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Gallus gallus)


name: PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Bos taurus)


name: (E)-non-2-enoate + 2 H(+) + NADPH => (E)-non-2-enal + H2O + NADP(+)


name: HSD17B1 hydrogenates E1 to EST17b (Mus musculus)


name: D-glucosamine 6-phosphate <=> D-galactosamine 6-phosphate


name: GATA4, GATA6, and ISL1:LDB1 bind the HAND2 gene (Homo sapiens)


name: H2O + mycophenolyl-CoA = CoA + H(+) + mycophenolate


name: cytidine(34) in mitochondrial tRNA + S-adenosyl-L-methionine = 5-methylcytidine(34) in mitochondrial tRNA + H(+) + S-adenosyl-L-homocysteine


name: apo-[ACP] + CoA <=> adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]


name: prostaglandin E1 = H2O + prostaglandin A1


name: (Z)-beta-farnesene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Furin cleaves pro-factor IX to factor IX (Homo sapiens)


name: Phosphorylation of LIMK-1 by PAK (Bos taurus)


name: depalmitoylated eNOS translocates from plasma membrane (Bos taurus)


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Danio rerio)


name: H(+) + nicotinate + phenyl 5-phospho-alpha-D-ribofuranoside => nicotinate beta-D-ribonucleotide + phenol


name: RAB33B:GTP binds RIC1:RGP1 (Dictyostelium discoideum)


name: L-arabinitol + NAD(+) => H(+) + L-xylulose + NADH


name: (3E)-2-oxohex-3-enedioate + H(+) = 2-oxopent-4-enoate + CO2


name: (2Z,6Z)-farnesyl diphosphate => (1S,5S,6S)-alpha-bergamotene + diphosphate


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)


name: PPT2 hydrolyses PALMCoA to PALM (Rattus norvegicus)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)


name: GluN1:GluN2B (GRIN1:GRIN2B) di-heterotetramers bind LIN7:CASK:APBA1, DLG1 and KIF17 (Homo sapiens)


name: SUCLG1/G2 cleaves succinyl-CoA (Xenopus tropicalis)


name: p25-bound CDK5 phosphorylates CDC25A (Homo sapiens)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Homo sapiens)


name: bromide + L-tyrosine + NADP(+) = 3-bromo-L-tyrosine + NADPH


name: L-serine + taurocholate <=> L-serocholate + taurine


name: 2 cob(II)alamin-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] => 2 cob(I)alamin-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein]


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Danio rerio)


name: HOXD3 chromatin is activated (Homo sapiens)


name: Release of novel PDGFs as latent factors (Sus scrofa)


name: 2,4,5-trichlorocyclohexa-2,5-dien-1-ol + H2O = 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + chloride + H(+)


name: cGMP binds CNG channel to form cGMP:CNG channel (Sus scrofa)


name: Interaction of integrin alpha9beta1 with Tenascin-C (Mus musculus)


name: Autoproteolytic cleavage of Hh precursors (Sus scrofa)


name: a 5'-end triphospho-(purine-ribonucleoside) in mRNA + H2O <=> a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) + phosphate


name: a 3-demethylubiquinol + S-adenosyl-L-methionine <=> a ubiquinol + H(+) + S-adenosyl-L-homocysteine


name: a uridine in 12S rRNA + S-adenosyl-L-methionine = a 5-methyluridine in 12S rRNA + H(+) + S-adenosyl-L-homocysteine


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O <=> a 2'-deoxyribonucleoside + H(+) + triphosphate


name: (6R)-10-formyltetrahydrofolate + H2O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH


name: SUMOylation of PML with SUMO3 (Rattus norvegicus)


name: p38 MAPK activation by VEGFR (Rattus norvegicus)


name: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO2 + NADH


name: NPAS4 binds RET gene enhancer (Homo sapiens)


name: glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex (Rattus norvegicus)


name: (R)-pantetheine + CO2 => H(+) + N-[(R)-pantothenoyl]-L-cysteine


name: PHF20 binds TP53 dimethylated on K370 and K382 (Canis familiaris)


name: 2-trans-(+)-abscisate + UDP-alpha-D-glucose = beta-D-glucopyranosyl trans-(+)-abscisate + UDP


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 <=> A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O


name: Caspase-mediated cleavage of MASK (Gallus gallus)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Canis familiaris)


name: (E,E)-piperate + ATP + CoA <=> (E,E)-piperoyl-CoA + AMP + diphosphate


name: voltage-gated sodium channel activity involved in Purkinje myocyte action potential


name: chloride(out) + nitrate(in) => chloride(in) + nitrate(out)


name: bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE (Mus musculus)


name: holo-[peptidyl-carrier protein] + L-cysteinyl-5'-AMP = AMP + H(+) + L-cysteinyl-[peptidyl-carrier protein]


name: 3-sulfanylpropanoate + O2 => 3-sulfinopropanoate + H(+)


name: folate(in) + H(+)(in) => folate(out) + H(+)(out)


name: 3-oxodecanedioyl-CoA + CoA => acetyl-CoA + octanedioyl-CoA


name: (2R,3S)-3-methylmalate + NAD(+) = 3-carboxy-2-oxobutanoate + H(+) + NADH


name: 2 (+)-geodin + 2 H2O => 2 dihydrogeodin + 2 H(+) + O2


name: Opioid receptors bind opioid peptides (Rattus norvegicus)


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Mus musculus)


name: MTTP binds lomitapide (Rattus norvegicus)


name: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) => a 3-oxosteroid + CO2 + NADH


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione => (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Homo sapiens)


name: (R)-N-methylcoclaurine + (S)-N-methylcoclaurine + O2 + reduced [NADPH--hemoprotein reductase] = berbamunine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane (Homo sapiens)


name: p-PKR dimer phosphorylates SPHK1 (Rattus norvegicus)


name: C3 convertases spontaneously dissociate (Mus musculus)


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Caenorhabditis elegans)


name: PARVB interacts with Alpha-actinin (Caenorhabditis elegans)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Rattus norvegicus)


name: p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Sus scrofa)


name: tBID binds to inactive BAX protein (Mus musculus)


name: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA => 10-deacetylbaccatin III + CoA


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: (4-hydroxyphenyl)acetaldehyde + H2O + NAD(+) = 4-hydroxyphenylacetate + 2 H(+) + NADH


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Mus musculus)


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Saccharomyces cerevisiae)


name: an alkylmercury + H(+) = an alkane + Hg(2+)


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Rattus norvegicus)


name: 5,10-methylenetetrahydromethanopterin + NAD(+) => 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH


name: Retromer recycles WLS to the Golgi (Sus scrofa)


name: 2-oxoglutarate + gibberellin A53 + O2 = CO2 + gibberellin A44 + succinate


name: ATP + sedoheptulose <=> ADP + D-sedoheptulose 7-phosphate + H(+)


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Rattus norvegicus)


name: H2O + N(8)-acetylspermidine => acetate + spermidine


name: dAMP(in) + phosphate(out) => dAMP(out) + phosphate(in)


name: a quinol + beta-nicotinamide D-riboside => 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+)


name: H2O + ochratoxin A => L-phenylalanine + ochratoxin alpha


name: 2 9-riburonosylhypoxanthine + 2 H(+) => 2 5'-dehydroinosine + O2


name: GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol (Danio rerio)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Homo sapiens)


name: 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA <=> 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: D-maltotriose + O2 <=> D-maltotriono-1,5-lactone + H2O2


name: decanoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxododecanoyl-[ACP] + CO2 + holo-[ACP]


name: RNA demethylases demethylate N6-methyladenosine RNA (Xenopus tropicalis)


name: Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Mus musculus)


name: 1-O-(9Z)-hexadecenyl (9Z)-octadecenoate + CoA => (9Z)-hexadecen-1-ol + (9Z)-octadecenoyl-CoA


name: ERK1/2/5 activate RSK1/2/3 (Saccharomyces cerevisiae)


name: Met1-linked polyubiquitin deubiquitinase activity


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Homo sapiens)


name: CMP-N-acetyl-beta-neuraminate(in) + UMP(out) => CMP-N-acetyl-beta-neuraminate(out) + UMP(in)


name: Estrogen-responsive CHD1 gene transcription (Homo sapiens)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Xenopus tropicalis)


name: TGFBR3 complex binds to TGFBR2 (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylethanolamine <=> 2-(acylamino)ethyl fatty acid + a monoacyl-sn-glycero-3-phosphocholine


name: Fe-coproporphyrin III + 2 H(+) + 2 H2O2 <=> 2 CO2 + 4 H2O + heme b


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Rattus norvegicus)


name: cytidine(49) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(49) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2) => H2O + N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,2)


name: Phospholipase C-gamma1 binds to the activated EGF receptor (Rattus norvegicus)


name: glycine + octanoyl-CoA = CoA + H(+) + N-octanoylglycine


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Gallus gallus)


name: VEGFA-165 dimer binds VEGFR2 dimer (Canis familiaris)


name: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose => alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: fumarate + L-aspartate <=> iminosuccinate + succinate


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Schizosaccharomyces pombe)


name: N-acetylindoxyl + O2 <=> H2O + N-acetylisatin


name: glutathione S,S-dioxide + H2O = glutathione + H(+) + sulfite


name: Duplex miRNA is loaded into Argonaute (Canis familiaris)


name: 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: FeHM dissociates from MetHb (Homo sapiens)


name: n H(+)(in) + spermine(out) => n H(+)(out) + spermine(in)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Homo sapiens)


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Danio rerio)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Danio rerio)


name: Group 3 - Selective Cl- transport (Sus scrofa)


name: MRE11 binds cytosolic DNA (Rattus norvegicus)


name: SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ (Mus musculus)


name: ATP + H(+) + IC-asc-C7 => diphosphate + IC-asc-C7-AMP


name: H2O + hypothiocyanous acid => H(+) + H2O2 + thiocyanate


name: 2'''-acetyl-6'''-hydroxyneomycin C + H2O <=> 6'''-deamino-6'''-hydroxyneomycin C + acetate


name: STAT1 and STAT3 dimers translocate to the nucleus (Danio rerio)


name: Change of PKC theta conformation (Sus scrofa)


name: (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine <=> 4-(trimethylamino)butanal + glycine


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Sus scrofa)


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Bos taurus)


name: CoA + glutathione + NADP(+) = CoA-glutathione + H(+) + NADPH


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2A (GRIN2A) (Canis familiaris)


name: H2O + sucrose 6(F)-phosphate => phosphate + sucrose


name: The BH3 radical can decay to dihydrobiopterin (BH2) (Homo sapiens)


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Xenopus tropicalis)


name: cyclopentylamine + H2O + NADP(+) = cyclopentanone + H(+) + NADPH + NH4(+)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + H(+)(in) <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + H(+)(out)


name: lathosterol + NADP(+) <=> 5alpha-cholesta-7,24-dien-3beta-ol + H(+) + NADPH


name: SPHK2 binds SPHK2 inhibitors (Schizosaccharomyces pombe)


name: ATP + hydrogencarbonate + propanoyl-CoA => ADP + H(+) + methylmalonyl-CoA + phosphate


name: SUMOylation of TOP2B with SUMO1 (Rattus norvegicus)


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: 3 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) => 3 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: Defective CYP27B1 does not hydroxylate CDL (Homo sapiens)


name: Activated FGFR1 binds FRS3 (Xenopus tropicalis)


name: Polymeric PGN binds to PGRP-LCx at the plasma membrane (Drosophila melanogaster)


name: 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O => (9Z,12Z)-octadecadienoate + glycerol + H(+)


name: SUMOylation of NR1I2 with SUMO3 (Rattus norvegicus)


name: DOLPP1 dephosphorylates DOLDP to DOLP (Dictyostelium discoideum)


name: G-protein subunits dissociate from WNT:FZD complex (Homo sapiens)


name: H2O + juvenile hormone I = H(+) + juvenile hormone I carboxylate + methanol


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Homo sapiens)


name: TP53 family members bind the TP53I3 (PIG3) gene promoter (Homo sapiens)


name: 25(OH)D translocates from lysosomal lumen to cytosol (Homo sapiens)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Schizosaccharomyces pombe)


name: SCD desaturates ST-CoA to OLE-CoA (Xenopus tropicalis)


name: The Kiss receptor GPR54 binds kisspeptin (Canis familiaris)


name: JAK2 phosphorylation of IRS-1/2 (Homo sapiens)


name: ATP + formate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide => ADP + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate


name: CLPXP binds mitochondrial matrix proteins (Homo sapiens)


name: (3R)-hydroxytetracosanoyl-CoA => (2E)-tetracosenoyl-CoA + H2O


name: p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Xenopus tropicalis)


name: Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Canis familiaris)


name: H2O + L-alanyl-L-threonine = L-alanine + L-threonine


name: Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)


name: ME2 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)


name: D-glyceraldehyde 3-phosphate + L-arginine => H(+) + N(2)-(2-carboxyethyl)-L-arginine + phosphate


name: Active calmodulin binds CAMK2 (Plasmodium falciparum)


name: Phosphorylation of Platelet Sec-1 (Drosophila melanogaster)


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Bos taurus)


name: RHOU binds effectors at the plasma membrane (Bos taurus)


name: PIAS2-1 SUMOylates PARK7 with SUMO1 (Caenorhabditis elegans)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Danio rerio)


name: a Fe(III)-siderophore(in) + ADP + H(+) + phosphate => a Fe(III)-siderophore(out) + ATP + H2O


name: POLZ extends translesion synthesis (Drosophila melanogaster)


name: PAK phosphorylates p21 RAF1 on S338 (Mus musculus)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Bos taurus)


name: Antizyme OAZ binds to Ornithine decarboxylase (Canis familiaris)


name: DCAKD phosphorylates DP-CoA (Caenorhabditis elegans)


name: pyrimidine-specific mismatch base pair DNA N-glycosylase activity


name: factor VIIIa + factor IXa -> factor VIIIa:factor IXa (Mus musculus)


name: H(+)(out) + L-lysine(out) => H(+)(in) + L-lysine(in)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Drosophila melanogaster)


name: beta-D-glucose 6-phosphate => beta-D-glucose 1-phosphate


name: 5,6,7,8-tetrahydromethanopterin + A = 7,8-dihydromethanopterin + AH2


name: histone H3K9 monomethyltransferase activity


name: NADP(+) + octanoyl-CoA => (2E)-octenoyl-CoA + H(+) + NADPH


name: H2O + L-leucine + NAD(+) <=> 4-methyl-2-oxopentanoate + H(+) + NADH + NH4(+)


name: 2-dehydro-3-deoxy-D-arabinonate <=> 2,5-dioxopentanoate + H2O


name: 2-heptyl-3-hydroxy-4(1H)-quinolone + O2 = CO + H(+) + N-octanoylanthranilate


name: H2O + N-(9Z-octadecenoyl)-(4R)-hydroxysphinganine <=> (4R)-hydroxysphinganine + (9Z)-octadecenoate


name: HSP90:FKBP4:PTGES3 binds HSF1 trimer (Homo sapiens)


name: MAOB:FAD oxidatively deaminates TYR (Bos taurus)


name: (7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate = diphosphate + N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate


name: type 7 metabotropic glutamate receptor binding


name: Activated FGFR4 mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out)


name: chloroacetaldehyde + H2O + NADP(+) => chloroacetate + 2 H(+) + NADPH


name: 2-(1-hydroxyethyl)thiamine diphosphate + 2-oxobutanoate => (S)-2-ethyl-2-hydroxy-3-oxobutanoate + thiamine diphosphate


name: Insulin secretory granule translocates to cell cortex (Homo sapiens)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Mus musculus)


name: PGAM5 dodecamer dephosphorylates p-S336-ME1 (Mus musculus)


name: dihydrobisanhydrobacterioruberin + diphosphate => dimethylallyl diphosphate + H2O + isopentenyldehydrorhodopin


name: 3,5,6-trichloropyridin-2-ol + FADH2 + O2 = 3,6-dichloropyridine-2,5-dione + chloride + FAD + 2 H(+) + H2O


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine => 2 a 1-acyl-sn-glycero-3-phosphocholine


name: (9Z,12Z)-octadecadienoate + O2 => (13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H(+) => (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O


name: HIPK2 phosphorylates RUNX1 and EP300 (Canis familiaris)


name: MRSBs reduce L-methyl-(R)-S-oxide to L-methionine (Danio rerio)


name: A + L-sorbopyranose = 1-dehydro-L-sorbose + AH2


name: Formation of TRAP coactivator complex (Sus scrofa)


name: P2X7 mediates loss of intracellular K+ (Sus scrofa)


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Rattus norvegicus)


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Danio rerio)


name: Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Sus scrofa)


name: Interaction of other tyrosine kinases with p-KIT (Sus scrofa)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + D-alanine + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine


name: UDP-alpha-D-glucose + vomilenine => H(+) + raucaffricine + UDP


name: S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity


name: NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Schizosaccharomyces pombe)


name: DVL2 binds phosphorylated WWTR1 (TAZ) (Xenopus tropicalis)


name: L-arabinitol + NADP(+) => H(+) + L-arabinose + NADPH


name: diphosphate + sobralene => (2E,6E,10E)-geranylgeranyl diphosphate


name: AICAR + 10-Formyl-THF => FAICAR + THF (Schizosaccharomyces pombe)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Homo sapiens)


name: Expression of DLL1 in presomitic mesoderm (Homo sapiens)


name: Dimerization of procollagen type VI (Mus musculus)


name: GSS:Mg2+ dimer synthesizes GSH (Homo sapiens)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Schizosaccharomyces pombe)


name: RBBP7 binds histone H3 (Caenorhabditis elegans)


name: 3-hydroxyisovaleryl-CoA <=> 3-methyl-(2E)-butenoyl-CoA + H2O


name: SLC45A3 transports Glc from extracellular region to cytosol (Danio rerio)


name: 5,6-dihydrouridine(20a) in tRNA + NADP(+) = H(+) + NADPH + uridine(20a) in tRNA


name: ATP + cob(II)yrinate + H2O + L-glutamine = ADP + cob(II)yrinate c monoamide + H(+) + L-glutamate + phosphate


name: 2 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 2 H(+) + O2 = 2 aureusidin 6-O-beta-glucoside + 2 H2O


name: a 2'-deoxyribonucleoside + a ribonucleoside 5'-phosphate => a 2'-deoxyribonucleoside 5'-phosphate + a ribonucleoside


name: candesartan O-beta-D-glucuronoside + UDP => candesartan + UDP-alpha-D-glucuronate


name: 4-hydroxybenzaldehyde + acetate => 3-hydroxy-3-(4-hydroxyphenyl)propanoate


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Bos taurus)


name: Endocytosis of TGFBR3:ARRB complex (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate = beta-myrcene + diphosphate


name: NICD4 traffics to the nucleus (Rattus norvegicus)


name: FH tetramer hydrates fumarate to L-malate (Caenorhabditis elegans)


name: Re-integration of insulin receptor into plasma membrane (Canis familiaris)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Plasmodium falciparum)


name: cyclic nucleotide phosphodiesterase activator activity


name: Beclin-1 complex translocates to the ER (Rattus norvegicus)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Mus musculus)


name: 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: 2 hydrogencarbonate(out) + Mn(2+)(out) => 2 hydrogencarbonate(in) + Mn(2+)(in)


name: pseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-homocysteine


name: SPHK2 binds SPHK2 inhibitors (Dictyostelium discoideum)


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(out) + ADP + H(+) + phosphate => 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(in) + ATP + H2O


name: 4-nitrobenzaldehyde + H(+) + NADPH = 4-nitrobenzyl alcohol + NADP(+)


name: VAV1 is a GEF for Rho/Rac family GTPases (Drosophila melanogaster)


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Bos taurus)


name: Adenylate cyclase converts ATP into cyclic AMP (Canis familiaris)


name: PKC-delta translocates to plasma membrane (Mus musculus)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16alpha,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: BIL translocates to the nucleus (Homo sapiens)


name: TRAIL binds TRAIL receptors (Rattus norvegicus)


name: Monoiodinated tyrosine can be deiodinated (Drosophila melanogaster)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Danio rerio)


name: Ubiquitinated DVL is degraded by the proteasome (Rattus norvegicus)


name: MHC class II antigen processing (Homo sapiens)


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Danio rerio)


name: FUT2 transfers Fuc to LeA to form LeB (Sus scrofa)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] => 16alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + isovitexin 2''-O-beta-D-glucoside + UDP => isovitexin + UDP-alpha-D-glucose


name: D-sorbitol dehydrogenase (acceptor) activity


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Canis familiaris)


name: 2 A + a carotenoid beta-end derivative = a carotenoid chi-end derivative + 2 AH2


name: PITPNM1,2,3 exchange PI for PA (Canis familiaris)


name: POLD,POLE binds deISGylated PCNA after TLS (Mus musculus)


name: benzoyl-CoA + glycine = CoA + H(+) + N-benzoylglycine


name: a very-long-chain 2,3-saturated fatty acyl-CoA + O2 => a very-long-chain (2E)-enoyl-CoA + H2O2


name: guanosine(2535) in 23S rRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methylguanosine(2535) in 23S rRNA + S-adenosyl-L-homocysteine


name: 3',3'-cGAMP(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) <=> 3',3'-cGAMP(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: H(+)(out) + L-leucine(in) = H(+)(in) + L-leucine(out)


name: CBL binds InlB-activated MET (Homo sapiens)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Canis familiaris)


name: "type I site-specific deoxyribonuclease"


name: B3GNT5 transfers GlcNAc to LacCer (Danio rerio)


name: Interleukin-12 dissociates from Interleukin-12 receptor (Rattus norvegicus)


name: L-lysyl-[glycine-cleavage complex H protein] + N(6)-octanoyl-L-lysyl-[lipoyl-carrier protein] => L-lysyl-[lipoyl-carrier protein] + N(6)-octanoyl-L-lysyl-[glycine-cleavage complex H protein]


name: AKT1S1 (PRAS40) binds mTORC1 (Mus musculus)


name: NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)


name: 3beta-hydroxyandrost-5-en-17-one + O2 + reduced [NADPH--hemoprotein reductase] = 3beta,7alpha-dihydroxyandrost-5-en-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PDP1,2 dephosphorylate p-lipo-PDH (Rattus norvegicus)


name: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+)


name: dimethyl sulfoxide + H2O + NAD(+) => dimethyl sulfone + H(+) + NADH


name: CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Dictyostelium discoideum)


name: 3-oxochol-4-en-24-oyl-CoA + NAD(+) <=> 3-oxochol-4,6-dien-24-oyl-CoA + H(+) + NADH


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate <=> 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Xenopus tropicalis)


name: H2O + N-acetylputrescine + O2 <=> 4-acetamidobutanal + H2O2 + NH4(+)


name: O2 + phylloquinone + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein reductase]


name: H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol = a fatty acid + H(+) + long chain acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: Interaction of Csk with PAG (Canis familiaris)


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Mus musculus)


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Rattus norvegicus)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine => a diacylglycerol + an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine


name: G protein-coupled estrogen receptor 1 binds estrogen non-classically (Canis familiaris)


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Rattus norvegicus)


name: Bile salts and acids dissociate from ALB (Sus scrofa)


name: p-PKR dimer phosphorylates PTPN2 (Homo sapiens)


name: JAK1-activated RAF1 phosphorylates MAPKs (Rattus norvegicus)


name: activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin (Bos taurus)


name: cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + cholesterol


name: Interaction of integrin alpha8beta1 with Tenascin-C (Canis familiaris)


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Mus musculus)


name: PAF receptor binds platelet activating factor (Homo sapiens)


name: a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycerol => a triacyl-sn-glycerol + glycerol


name: Cross-linking of FCGRIA with IgG-coated Ag (Rattus norvegicus)


name: D-xylobiose + O2 => D-xylobiono-1,5-lactone + H2O2


name: G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) (Homo sapiens)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 = (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate


name: an N-choloyl-L-alpha-amino acid + H2O => an L-alpha-amino acid + cholate


name: (Z,E)-alpha- farnesene synthase activity


name: H2O + sepiapterin <=> 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+)


name: FMN(in) + NAD(+)(out) => FMN(out) + NAD(+)(in)


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Canis familiaris)


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Mus musculus)


name: RHOD binds effectors at the mitochondrial outer membrane (Xenopus tropicalis)


name: a quinone + 2 H(+) + hydrogen sulfide + sulfite = a quinol + thiosulfate


name: EDNRA, EDNRB bind non-selective ERAs (Xenopus tropicalis)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Sus scrofa)


name: 4-O-demethylbarbatate + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin II


name: The acetyl group from acetyl-CoA is transferred to the NAT1 (Danio rerio)


name: (2E)-geranyl diphosphate + H2O = diphosphate + sabinene hydrate


name: L-glutamate(in) + N-acetyl-L-cysteine(out) => L-glutamate(out) + N-acetyl-L-cysteine(in)


name: dihydroxyacetone phosphate + H2O => dihydroxyacetone + phosphate


name: chloroorienticin B + dTDP-beta-L-vancosamine <=> chloroeremomycin + dTDP + H(+)


name: 1D-myo-inositol 3-phosphate + H2O <=> myo-inositol + phosphate


name: a hydroperoxyeicosatetraenoate = an oxoeicosatetraenoate + H2O


name: CDKN1B is phosphorylated in response to estrogen (Gallus gallus)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Homo sapiens)


name: ent-kaur-16-en-19-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => ent-kaur-16-en-19-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: D-histidine + S-adenosyl-L-methionine <=> (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: Formation of p-STAT1 homodimer (Sus scrofa)


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Saccharomyces cerevisiae)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Plasmodium falciparum)


name: 2-(acetamidomethylene)succinate + NADP(+) => 3-hydroxy-2-methylpyridine-5-carboxylate + NADPH + O2


name: D-galactono-1,4-lactone + H2O = D-galactonate + H(+)


name: activating MHC class I receptor activity


name: a cholesterol ester + H2O <=> a fatty acid + cholesterol + H(+)


name: 7-deoxyloganin + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + loganin + oxidized [NADPH--hemoprotein reductase]


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Rattus norvegicus)


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Canis familiaris)


name: RHOD GAPs stimulate RHOD GTPase activity (Bos taurus)


name: cholesteryl (9Z,12Z)-octadecadienoate(out) => cholesteryl (9Z,12Z)-octadecadienoate(in)


name: LIG1 binds APEX1 and PCNA at SSB (Homo sapiens)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Canis familiaris)


name: Rap1 signal termination by Rap1GAPs (Dictyostelium discoideum)


name: TBK1 is phosphorylated within the activated TLR4 complex (Sus scrofa)


name: atROL binds to RBP2 (Xenopus tropicalis)


name: XDH oxidizes hypoxanthine to form xanthine (Canis familiaris)


name: D-galactosamine 6-phosphate = alpha-D-galactosamine 1-phosphate


name: Dissociation of RAS:RAF1 mutant complex (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine


name: Association of Golgi  transport vesicles with microtubules (Bos taurus)


name: glycerol transmembrane transporter activity


name: 3-(3-hydroxyphenyl)propanoate(out) + H(+)(out) => 3-(3-hydroxyphenyl)propanoate(in) + H(+)(in)


name: Pellino binds hp-IRAK1:TRAF6 (Sus scrofa)


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Bos taurus)


name: Proteasomal cleavage of substrate (Dictyostelium discoideum)


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycerol + CDP-choline = a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: JLP interacts with CDO complex (Homo sapiens)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Bos taurus)


name: GGPS1 hexamer transfers IPPP to DMAPP (Saccharomyces cerevisiae)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Sus scrofa)


name: a triacylglycerol + all-trans-retinol = a diacylglycerol + an all-trans-retinyl ester


name: miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 11-oxomiltiradiene + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: NADP(+) + prostaglandin F2alpha <=> H(+) + NADPH + prostaglandin D2


name: gibberellin A20 + S-adenosyl-L-methionine = gibberellin A20 methyl ester + S-adenosyl-L-homocysteine


name: formate(in) + oxalate(out) => formate(out) + oxalate(in)


name: isoxazolin-5-one + O-acetyl-L-serine <=> 3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate + H(+)


name: (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA = (E)-2-benzylidenesuccinyl-CoA + H2O


name: PP2A demethylation by PPME1 (Canis familiaris)


name: PKR binds activating host RNA (Mus musculus)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen (Danio rerio)


name: JMJD1C demethylates H3K9 mono- and di-methylation (Sus scrofa)


name: Association of DFF40 with chromatin (Homo sapiens)


name: 3-hydroxybutane-1,2,3-tricarboxylate <=> 2-methyl-cis-aconitate + H2O


name: SLC9B2 exchanges Na+ for H+ (Gallus gallus)


name: MAPKAPK2 phosphorylates RIPK1 at S320 (Mus musculus)


name: H2O + L-serine + NAD(+) <=> 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose <=> [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n+1)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + salvigenin = 8-hydroxysalvigenin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PDPK1 phosphorylates PKN1,2,3 (Homo sapiens)


name: Expression of DUX4 in the zygote (Homo sapiens)


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Dictyostelium discoideum)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Mus musculus)


name: ERBB2 promotes PTK6 autophosphorylation (Homo sapiens)


name: L-arginyl-[protein] + methylglyoxal <=> N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein]


name: (13Z)-docosenamide + H2O => (13Z)-docosenoate + NH4(+)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Bos taurus)


name: Translocation of COP1 from the nucleus to the cytoplasm (Sus scrofa)


name: 13-methyltetradecanal + phosphoethanolamine => 15-methylhexadecasphinganine 1-phosphate


name: digitoxin + 2 Fe(II)-[cytochrome c] + 3 H(+) => dihydrodigitoxin + 2 Fe(III)-[cytochrome c]


name: (1E,2S)-2-methylbutanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => L-isoleucine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: RhCG mediates ammonium efflux out of kidney collecting duct cells (Dictyostelium discoideum)


name: ARV1 transports CHOL from ER membrane to plasma membrane (Sus scrofa)


name: H2O2 + N-(4-oxobutylpyrrolinium) ion + NH4(+) => H2O + N-(4-aminobutylpyrrolinium) ion + O2


name: SUMOylation of Histone H4 with SUMO3 (Drosophila melanogaster)


name: 1-hexadecanoylglycerone 3-phosphate + tetradecan-1-ol = 1-O-tetradecylglycerone 3-phosphate + H(+) + hexadecanoate


name: a dicarboxylate(in) + L-sepiapterin(out) <=> a dicarboxylate(out) + L-sepiapterin(in)


name: carboxymethoxysuccinate <=> fumarate + glycolate


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)


name: a 1-acyl-sn-glycero-3-phosphocholine + a triacylglycerol => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacylglycerol


name: InlB:MET dimer trans-autophophorylates (Homo sapiens)


name: JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Mus musculus)


name: 1D-myo-inositol hexakisphosphate + ATP = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP


name: MLXIPL:MLX binds ACACA gene promoter (Homo sapiens)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 => (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO2 + H2O + succinate


name: S-adenosyl-L-methionine + uridine(32) in tRNA = 2'-O-methyluridine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => 24,25-dihydrolanosterol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] 4'-O-beta-D-glucuronide + UDP


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Rattus norvegicus)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + parthenolide => (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase]


name: dTTP + 2 H2O => dTMP + 2 H(+) + 2 phosphate


name: BRAF autophosphorylates downstream of RAP1 and NGF (Gallus gallus)


name: hexadecane + O2 + reduced [NADPH--hemoprotein reductase] = 9-hexadecanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (1R,4R)-5-oxo-1,2-campholide = [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)


name: Extracellular BTD hydrolyses BCTN (Bos taurus)


name: 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate => beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O


name: an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] <=> a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + variediene


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Rattus norvegicus)


name: (6S)-5,6,7,8-tetrahydrofolate + NADP(+) <=> 7,8-dihydrofolate + H(+) + NADPH


name: Autophosphorylation of PDGF alpha/beta receptors (Danio rerio)


name: 4-(trimethylamino)butanal + H2O + NAD(+) <=> 4-(trimethylamino)butanoate + 2 H(+) + NADH


name: 3,3',5-triiodo-L-thyronine + A + H(+) + iodide = AH2 + L-thyroxine


name: PA is converted to CDP-DAG by CDS1 (Caenorhabditis elegans)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Schizosaccharomyces pombe)


name: 2-demethylmenaquinone-8 + H2O + trimethylamine => 2-demethylmenaquinol-8 + H(+) + trimethylamine N-oxide


name: TRIM27 binds PTEN (Caenorhabditis elegans)


name: Translocation of COP1 from the nucleus to the cytoplasm (Homo sapiens)


name: GRK5 sequesters activated Gq (Homo sapiens)


name: (R)-carnitine + propanoyl-CoA => CoA + O-propanoyl-(R)-carnitine


name: an adenosine in mRNA + S-adenosyl-L-methionine => an N(1)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: Cleavage of 3-methyladenine by MPG glycosylase  (Canis familiaris)


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Sus scrofa)


name: 5,10-dihydrophenazine-1,6-dicarboxylate + O2 = H2O2 + phenazine-1,6-dicarboxylate


name: hydrogencarbonate(in) + Na(+)(in) => hydrogencarbonate(out) + Na(+)(out)


name: Complement factor I complex formation (Drosophila melanogaster)


name: dolabradiene + O2 + reduced [NADPH--hemoprotein reductase] <=> 15,16-epoxydolabrene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => a fatty acid + H(+) + sn-glycero-3-phospho-1D-myo-inositol


name: XPC binds RAD23 and CETN2 (Rattus norvegicus)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Danio rerio)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Xenopus tropicalis)


name: H2O + O2 + spermine <=> H2O2 + NH4(+) + spermine monoaldehyde


name: (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2


name: AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)


name: (-)-geosmin + acetone => (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O


name: TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)


name: CYP7B1 7-hydroxylates 25OH-CHOL (Canis familiaris)


name: RNF41 binds neuregulin-activated ERBB3 (Drosophila melanogaster)


name: N-[omega-(9Z,12Z)-octadecadienoyloxy]-acylsphin-4-enine + O2 = N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine


name: H2O + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD(+) <=> (S)-2,3-diaminopropanoate + 2-oxoglutarate + H(+) + NADH


name: H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate


name: LPA-binding receptors bind LPA (Mus musculus)


name: (3R)-hydroxy-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + NADP(+) => 3-oxo-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H(+) + NADPH


name: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters


name: "Exonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters"


name: mitogen-activated protein kinase kinase kinase kinase binding


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Homo sapiens)


name: EHD proteins interact with Rabenosyn-5 (Homo sapiens)


name: 2 H(+) + Ni-sirohydrochlorin => Ni(2+) + sirohydrochlorin


name: ADP-alpha-D-glucose + sn-glycerol 3-phosphate = 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + ADP + H(+)


name: CDH11 forms homotypic trans dimer (Homo sapiens)


name: D-arabinitol + NADP(+) = D-xylulose + H(+) + NADPH


name: butanoyl-CoA + hexan-1-ol = CoA + hexyl butanoate


name: SENP1,2,5 proteolytically process SUMO2 (Xenopus tropicalis)


name: DNA-PKcs autophosphorylates (Bos taurus)


name: 2-oxo-3-sulfanylpropanoate + L-cysteinyl-[protein] = pyruvate + S-sulfanyl-L-cysteinyl-[protein]


name: H2O + O2 + urate => 5-hydroxyisourate + H2O2


name: p-PKR dimer phosphorylates MAPT (Mus musculus)


name: butanoyl-CoA + NADP(+) <=> (2E)-butenoyl-CoA + H(+) + NADPH


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Rattus norvegicus)


name: 2 ATP + L-proline + L-tryptophan = 2 AMP + brevianamide F + 2 diphosphate + 2 H(+)


name: glyoxylate + L-tyrosine <=> 3-(4-hydroxyphenyl)pyruvate + glycine


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Homo sapiens)


name: G13 activation by TP receptor (Rattus norvegicus)


name: 1,3,3'-tri-O-methyl-4alpha-mannobiose + H(+) + S-adenosyl-L-homocysteine => 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine


name: (3S)-3-isopropenyl-6-oxoheptanoate + H(+) => (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one


name: CRK,CRKL recruits RAC1 GEF to activated MET (Bos taurus)


name: Formation of DRIP coactivator complex (Sus scrofa)


name: Activation of Ca-permeable Kainate receptors (Bos taurus)


name: ATM phosphorylates EYA1-4 (Canis familiaris)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O <=> diphosphate + ophiobolin F


name: 2-oxoglutarate + a 5-formyl-2'-deoxycytidine in DNA + O2 <=> a 5-carboxyl-2'-deoxycytidine in DNA + CO2 + H(+) + succinate


name: IRAK2 induces TRAF6 oligomerization (Bos taurus)


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Bos taurus)


name: 3-(hydrohydroxyphosphoryl)pyruvate + CO2 => 1-carboxyvinyl carboxyphosphonate + H(+)


name: Rheb in the MTORC1 complex hydrolyses GTP (Sus scrofa)


name: 1D-myo-inositol hexakisphosphate + H(+) + phosphate => 6-diphospho-1D-myo-inositol pentakisphosphate + H2O


name: 24-methylenecycloartanol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: D-glucosamine 6-phosphate(in) + L-histidyl-[protein] => D-glucosamine(out) + N(pros)-phospho-L-histidyl-[protein]


name: 2-oxoglutarate + GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+) => GDP-4-dehydro-alpha-D-rhamnose + L-glutamate


name: HLTF polyubiquitinates monoubiquitinated PCNA (Mus musculus)


name: (E)-prop-1-en-1-SO-peroxol = (Z)-propanethial S-oxide


name: atROL binds RBP1 to form RBP1:atROL (Caenorhabditis elegans)


name: Phosphorylation and activation of VAV (Mus musculus)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Dictyostelium discoideum)


name: Expression U2 small nuclear ribonucleoprotein A' (Homo sapiens)


name: Formation of NR-NCOR Corepressor Complex (Gallus gallus)


name: erythritol + NADP(+) => D-erythrose + H(+) + NADPH


name: beta-alanyl-[peptidyl-carrier protein] + tryptamine = beta-alanyl-tryptamine + H(+) + holo-[peptidyl-carrier protein]


name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Drosophila melanogaster)


name: (R)-3-(indol-3-yl)lactoyl-CoA = (E)-3-(indol-3-yl)acryloyl-CoA + H2O


name: NUMB:ITCH ubiquitinates GLI1 (Rattus norvegicus)


name: Digestion of diacylglycerols by extracellular PTL:colipase (Homo sapiens)


name: KRAS4B recycles to the plasma membrane (Sus scrofa)


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Xenopus tropicalis)


name: PNPLA7 hydrolyzes LysoPtdCho (Homo sapiens)


name: A4GALT transfers galactose to LacCer (Homo sapiens)


name: threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate (Homo sapiens)


name: (S)-miconazole(in) + ATP + H2O => (S)-miconazole(out) + ADP + H(+) + phosphate


name: 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+) => 4alpha-methyl-5alpha-cholest-8-en-3-one + H(+) + NADPH


name: 1,2,3-tributanoylglycerol + H2O <=> butanoate + dibutanoylglycerol + H(+)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Drosophila melanogaster)


name: ERBB2 TMD/JMD mutants bind trastuzumab (Homo sapiens)


name: USP2 deubiquitinates MDM2,MDM4 (Canis familiaris)


name: (1S,4S)-bornane-2,5-dione + FMNH2 + O2 = (1S,4S)-5-oxo-1,2-campholide + FMN + H(+) + H2O


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Bos taurus)


name: C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+) => 2 (S)-methylmalonyl-CoA + 10 H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 3 malonyl-CoA + 5 NADPH


name: H2O + substance P = L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-7)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol => a 1,2-diacylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Homo sapiens)


name: alpha-maltopentaose + phosphate = alpha-D-glucose 1-phosphate + alpha-maltotetraose


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Schizosaccharomyces pombe)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Mus musculus)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H(+) + UDP


name: N-methylethanolamine phosphate + S-adenosyl-L-methionine <=> H(+) + N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Drosophila melanogaster)


name: cAMP induces dissociation of inactive PKA tetramers (Rattus norvegicus)


name: 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine => 4',7-dihydroxy-3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol => a 1,3-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: folate + H(+) + NADPH => 7,8-dihydrofolate + NADP(+)


name: homogentisate + O2 <=> 4-maleylacetoacetate + H(+)


name: "pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase"


name: Loading of dopamine into synaptic veiscles (Rattus norvegicus)


name: 4-methylumbelliferone sulfate + phenol <=> 4-methylumbelliferone + phenyl sulfate


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-galactosamine => N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: H2O2 oxidizes Cys residues to form Cys-sulfenic acid (Homo sapiens)


name: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + H2O + NADP(+) <=> 3-oxo-5,6-didehydrosuberyl-CoA + 2 H(+) + NADPH


name: L-seryl-[EGF-like domain protein] + UDP-alpha-D-glucose => 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: chlorophyllide b + H(+) + NADH => 7(1)-hydroxychlorophyllide a + NAD(+)


name: ATP + H2O + hydrogenselenide => AMP + 2 H(+) + phosphate + selenophosphate


name: (3S)-hydroxydocosanoyl-CoA + NAD(+) <=> 3-oxodocosanoyl-CoA + H(+) + NADH


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Caenorhabditis elegans)


name: benzoate transmembrane transporter activity


name: RHOF GAPs stimulate RHOF GTPase activity (Caenorhabditis elegans)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Canis familiaris)


name: Trimerization of cytosolic HSF1 (Caenorhabditis elegans)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) <=> 6-lactoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH


name: CLIP1-LTK fusion binds PI3K to activate AKT (Homo sapiens)


name: acetyl-CoA + trans-glutaconate = (2E)-glutaconyl-CoA + acetate


name: 26S proteasome degrades Ub-NFE2L2 (Danio rerio)


name: 3-(3,4-dihydroxyphenyl)propanoate + NAD(+) => (E)-caffeate + H(+) + NADH


name: HRSP12 deaminates 2AA to 2OBUTA (Homo sapiens)


name: Formation of eEF1B complex (Dictyostelium discoideum)


name: DHCR24 reduces LAN to 24,25-dhLAN (Caenorhabditis elegans)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Sus scrofa)


name: hexacosanoyl-CoA + sphinganine = CoA + H(+) + N-hexacosanoylsphinganine


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Rattus norvegicus)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Caenorhabditis elegans)


name: CARM1 methylates arginine-18 (H3R17) of histone H3 (Bos taurus)


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Caenorhabditis elegans)


name: Association of procollagen type VI (Sus scrofa)


name: PDSS1,2 ligates FPP to IPPP (Sus scrofa)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Dictyostelium discoideum)


name: methylenetetrahydrofolate dehydrogenase (NAD+) activity


name: Formation of lysyl-pyrrole cross-links (Sus scrofa)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Mus musculus)


name: atROL binds RBP1 (parenchymal cell) (Rattus norvegicus)


name: 6alpha-hydroxy-28-norteasterone + O2 + reduced [NADPH--hemoprotein reductase] => 28-norteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: WNT ligands traffic to the plasma membrane (Rattus norvegicus)


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2A (GRIN2A) (Caenorhabditis elegans)


name: p-BMAL1:p-CLOCK,NPAS2 binds NAMPT gene (Homo sapiens)


name: LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Bos taurus)


name: DEGS2 oxygenates dihydroceramide (Schizosaccharomyces pombe)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O => 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2 = 2-dehydro-D-glucose + H2O2 + L-phenylalanine


name: ABCG4 may mediate cholesterol efflux (Bos taurus)


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)


name: 2-oxoglutarate(out) + hexanedioate(in) = 2-oxoglutarate(in) + hexanedioate(out)


name: Ferriheme is transferred from Methemoglobin to Hemopexin (Rattus norvegicus)


name: 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(2552) in 23S rRNA


name: 5-methylcytidine(2278) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(2278) in 25S rRNA + S-adenosyl-L-methionine


name: 3'-phosphoadenylyl sulfate + a ganglioside GM1b => adenosine 3',5'-bisphosphate + an 8-O-sulfo-ganglioside GM1b + H(+)


name: NTRK2-phosphorylated FRS2 binds GRB2 (Xenopus tropicalis)


name: MYO9B inactivates RHOA (Rattus norvegicus)


name: H2O + peregrinol diphosphate => diphosphate + viteagnusin D


name: [prokaryotic ubiquitin-like protein]-C-terminal-L-glutamate + NH4(+) => [prokaryotic ubiquitin-like protein]-C-terminal-L-glutamine + H2O


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Rattus norvegicus)


name: PRTPRF, PTPRS, PTPRD bind LRRC4B (Drosophila melanogaster)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Gallus gallus)


name: H(+) + pyrrole-2-carboxylate => 1H-pyrrole + CO2


name: a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + H(+) + NADH


name: IL24 binds to IL22RA1:JAK1:IL20RB (Sus scrofa)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + H(+) + phosphate


name: 4-hydroxymandelonitrile + UDP-alpha-D-glucose = H(+) + taxiphyllin + UDP


name: 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4beta-methylzymosterol-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Rattus norvegicus)


name: Y693-STAT4 dimer translocates to the nucleus (Gallus gallus)


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)


name: SMAD4 MH2 Domain Mutants do not bind phosphorylated SMAD2 and SMAD3 (Homo sapiens)


name: BIL dissociates from GSTA1, FABP1 (Sus scrofa)


name: Phosphorylated YBX1 translocates to the nucleus (Xenopus tropicalis)


name: H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + H2O => (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + phosphate


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Homo sapiens)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Dictyostelium discoideum)


name: (E)-cinnamate + H(+) + NADH => 3-phenylpropanoate + NAD(+)


name: (6E)-8-oxogeraniol + NAD(+) <=> (6E)-8-oxogeranial + H(+) + NADH


name: 2-dehydro-3-deoxy-L-rhamnonate + NAD(+) => 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Rattus norvegicus)


name: NLK translocates to nucleus (Homo sapiens)


name: USF1 is phosphorylated by p-MAPK14 (Gallus gallus)


name: chloride(out) + 2 Na(+)(out) + O-butanoyl-(R)-carnitine(out) => chloride(in) + 2 Na(+)(in) + O-butanoyl-(R)-carnitine(in)


name: di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine => di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP


name: Adenylate cyclase produces cAMP (Gallus gallus)


name: ESTG binds ESR2:chaperone complex (Danio rerio)


name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Homo sapiens)


name: (9Z)-18-hydroxyoctadecenoyl-CoA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9Z)-octadecenoyl-CoA + O2 + reduced [NADPH--hemoprotein reductase]


name: NAD-dependent protein demyristoylase activity


name: H2O + N(6)-tetradecanoyl-L-lysyl-[protein] + NAD(+) = 2''-O-tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: SCF-beta-TrCP ubiquitinylates IkB (Xenopus tropicalis)


name: SUMOylation of UBE2I with SUMO1 (Xenopus tropicalis)


name: CYB5A:heme reduces Asc.- to AscH- (Mus musculus)


name: SMURF2 monoubiquitinates SMAD3 (Homo sapiens)


name: PAN2-PAN3 complex partially deadenylates mRNA (Saccharomyces cerevisiae)


name: Caspase-mediated cleavage of Desmoglein 3 (Xenopus tropicalis)


name: 3 H(+) + hexanoyl-CoA + 3 malonyl-CoA = 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Homo sapiens)


name: 4-acetamidobutanal + H2O2 + propane-1,3-diamine => H2O + N(8)-acetylspermidine + O2


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Bos taurus)


name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (Bos taurus)


name: 3,4-dimethoxy-L-phenylalanine = 3,4-dimethoxy-(E)-cinnamate + NH4(+)


name: ADP + 2 H(+) + phosphoramidate => ATP + NH4(+)


name: LIPT2 transfers octanoyl group to GCSH (Xenopus tropicalis)


name: 3-(carbamoylamino)propanoate + 2 H(+) + H2O <=> beta-alanine + CO2 + NH4(+)


name: (4R,5R)-4,5-dihydroxycyclohex-2-ene-1-carbonyl-CoA + NADP(+) => (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carbonyl-CoA + H(+) + NADPH


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Canis familiaris)


name: Release of acetylcholine at the synapse (Rattus norvegicus)


name: H2O + L-seryl-tRNA(Thr) = L-serine + tRNA(Thr)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O <=> 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: 5-guanidino-2-oxopentanoate + S-adenosyl-L-methionine => (3R)-5-guanidino-3-methyl-2-oxopentanoate + H(+) + S-adenosyl-L-homocysteine


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Bos taurus)


name: 1-acyl LPE is acylated to PE by LPEAT (Canis familiaris)


name: Autophosphorylation of PAK (Xenopus tropicalis)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Schizosaccharomyces pombe)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Danio rerio)


name: TFRC dimer binds 2xholoTF (Mus musculus)


name: 3-hydroxydodecanoate + H(+) + NADPH + O2 <=> 3,12-dihydroxydodecanoate + H2O + NADP(+)


name: (R)-carnitine + an acyl-CoA = CoA + O-acyl-(R)-carnitine


name: Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition (Homo sapiens)


name: fumarate + H(+) + NADH => NAD(+) + succinate


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Rattus norvegicus)


name: (E)-cinnamoyl-CoA + CO2 + H2O2 => benzylmalonyl-CoA + H(+) + O2


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Dictyostelium discoideum)


name: 2-hydroxyoctanoate + O2 <=> 2-oxooctanoate + H2O2


name: NMRK2 phosphorylates NAR to yield NAMN (Homo sapiens)


name: carbazole 1,9a-dioxygenase [NAD(P)H] activity


name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria (Caenorhabditis elegans)


name: 7''-O-phosphohygromycin B + ADP + H(+) => ATP + hygromycin B


name: 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate + N-acetyl-beta-D-galactosamine


name: 1-hexadecanoyl-sn-glycero-3-phosphate + H2O => 1-hexadecanoyl-sn-glycerol + phosphate


name: alpha-D-glucose 1-phosphate + alpha-maltohexaose => alpha-maltoheptaose + phosphate


name: Degradation of ubiquitinated SKI/SKIL (Mus musculus)


name: RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)


name: 5-methylcytosine G/T mismatch specific DNA glycosylase mediated recognition and binding of thymine opposite guanine at CpG sequences (Gallus gallus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: AMP + decanoyl-CoA + diphosphate => ATP + CoA + decanoate


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Bos taurus)


name: Translocation of BMF to mitochondria (Mus musculus)


name: Syndecans 1, 2 & 4 bind VTN (Bos taurus)


name: a primary alcohol + 2 Fe(III)-[cytochrome c] <=> an aldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: AZD1979 oxetane hydrolysis product + H(+) => AZD1979 + H2O


name: acetyl-CoA + N-terminal L-methionyl-[tubulin] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]


name: a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione <=> a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O


name: a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GM1b (d18:1(4E)) + H2O


name: OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA (Drosophila melanogaster)


name: H2O + pyrrole-2-carboxylate = 1H-pyrrole + hydrogencarbonate


name: (Z)-(4-hydroxyphenyl)acetaldehyde oxime => 4-hydroxyphenylacetonitrile + H2O


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Mus musculus)


name: ATP + L-threonyl-[protein] => ADP + H(+) + O-phospho-L-threonyl-[protein]


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine <=> (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: Translocation of BMF to mitochondria (Sus scrofa)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: 3-hydroxy-3-(4-O-beta-D-glucosyl-3-methoxyphenyl)propanoate = 4-O-beta-D-glucosyl-vanillin + acetate


name: 1-phospho-alpha-D-glucuronate + ADP + H(+) => ATP + D-glucuronate


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Dictyostelium discoideum)


name: Activated FGFR4 phosphorylates FRS3 (Canis familiaris)


name: 2 ATP <=> 3',3'-c-di-AMP + 2 diphosphate


name: (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH => (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + NADP(+)


name: RAC1 GDIs block activation of RAC1 (Xenopus tropicalis)


name: p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Sus scrofa)


name: lysophosphatidic acid acyltransferase activity


name: IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Rattus norvegicus)


name: Interaction of NUMB with L1 (Homo sapiens)


name: PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Drosophila melanogaster)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Gallus gallus)


name: 1-octadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + pentanoate


name: Interaction of DAP12 and NKG2D (Homo sapiens)


name: PLC-gamma1 hydrolyses PIP2 (Danio rerio)


name: dehydrocholate + H(+) + NADPH => 7alpha-hydroxy-3,12-dioxo-5beta-cholanate + NADP(+)


name: CoA + O-(9Z)-octadecenoyl-(R)-carnitine => (9Z)-octadecenoyl-CoA + (R)-carnitine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] <=> a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester + apo--[retinol-binding protein]


name: (+)-copalyl diphosphate + H2O = (+)-copalol + diphosphate


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Homo sapiens)


name: hydrogencarbonate(out) + iodide(in) => hydrogencarbonate(in) + iodide(out)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Rattus norvegicus)


name: NH4(+) + pentanoate => H2O + pentanamide


name: ATP + CoA + isophthalate => AMP + diphosphate + isophthalyl-CoA


name: PDPK1 phosphorylates PKN1,2,3 (Sus scrofa)


name: Syk activation leads to SLP-76 activation (Bos taurus)


name: GGT dimers hydrolyse GSH (Saccharomyces cerevisiae)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Mus musculus)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Saccharomyces cerevisiae)


name: Cleavage of Procaspase-7 by the apoptosome (Sus scrofa)


name: hexanoyl-CoA + NADP(+) => (2E)-hexenoyl-CoA + H(+) + NADPH


name: a 1,3-diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base => a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O => (6S)-5,6,7,8-tetrahydrofolate + formaldehyde


name: aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate


name: CaMKK autophosphorylates in the cytosol (Canis familiaris)


name: Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 (Drosophila melanogaster)


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Sus scrofa)


name: bromide + FADH2 + melleolide F + O2 => 6'-bromomelleolide F + FAD + 2 H2O


name: p130 (RBL2) associates with MuvB to form DREAM complex (Canis familiaris)


name: 10-epi-gamma-eudesmol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Canis familiaris)


name: ATP + beta-D-fructose = ADP + beta-D-fructose 1-phosphate + H(+)


name: H2O + N-hexanoyl-sphinganine => hexanoate + sphinganine


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Drosophila melanogaster)


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: Further sulfation on galactose residues produces KSPG (Mus musculus)


name: Raf dimer inhibitors bind RAF heterodimers (Caenorhabditis elegans)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Plasmodium falciparum)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA <=> [O(7),N-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: L-seryl-tRNA(Sec) selenium transferase activity


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Bos taurus)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Canis familiaris)


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Rattus norvegicus)


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Sus scrofa)


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Xenopus tropicalis)


name: (E)-caffeoylpyruvate + H2O <=> (E)-caffeate + H(+) + pyruvate


name: Endocytosis of Ca impermeable AMPA receptors (Bos taurus)


name: cholesterol + PAPS => cholesterol sulfate + PAP (Danio rerio)


name: Caspase-mediated cleavage of Rock-1 (Sus scrofa)


name: 5-hydroxyuridine + ATP = 5-hydroxyuridine 5'-phosphate + ADP + H(+)


name: HMG CoA => acetoacetic acid + acetyl CoA (Sus scrofa)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Saccharomyces cerevisiae)


name: PIP3 recruits PDK1 and AKT to the membrane (Mus musculus)


name: butane-1-sulfonate + FMNH2 + O2 <=> butanal + FMN + 2 H(+) + H2O + sulfite


name: CBX3 and PRC1.6 associate with E2F6.com-1 (Drosophila melanogaster)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Sus scrofa)


name: BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose (Bos taurus)


name: Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Rattus norvegicus)


name: (25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 H2O + 2 oxidized [adrenodoxin]


name: H(+) + NADH + ubiquinone-10 <=> NAD(+) + ubiquinol-10


name: PDE3A hydrolyses cAMP to AMP (Homo sapiens)


name: L-cysteinyl-[protein] + methylglyoxal => S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein]


name: limonene-1,2-diol => H2O + limonene 1,2-epoxide


name: (2E,6E)-farnesyl diphosphate <=> (-)-vetispiradiene + diphosphate


name: PLC-gamma1 hydrolyses PIP2 (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate => (+)-guaia-6,9-diene + diphosphate


name: a short-chain fatty acyl-CoA + acetyl-CoA => a short-chain 3-oxoacyl-CoA + CoA


name: (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase] = 4-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TIFA oligomerization (Xenopus tropicalis)


name: MBTPS1 (S1P) cleaves CREB3L3 (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: CO2 + formaldehyde + L-lysyl(9)-[histone H3] + succinate => 2-oxoglutarate + N(6)-methyl-L-lysyl(9)-[histone H3] + O2


name: USP47 deubiquitinates POLB (Rattus norvegicus)


name: ME1 tetramer decarboxylates OA to PYR (Drosophila melanogaster)


name: CO2 + H2O + uridine-5'-carboxamide => (5'S,6'R)-C-glycyluridine + O2


name: Phosphorylation of STAT1 at Ser727 (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(+) + UDP


name: LPA-binding receptors bind LPA (Homo sapiens)


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Xenopus tropicalis)


name: sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen (Homo sapiens)


name: Thr-180 of ULK1 is phosphorylated (Gallus gallus)


name: mTORC1 phosphorylates MAF1 (Rattus norvegicus)


name: D-glutamate + NH4(+) => D-glutamine + H2O


name: 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: ATP + streptomycin = 6-O-adenylylstreptomycin + diphosphate


name: NTPDase4 hydrolyzes nucleoside diphosphates (Bos taurus)


name: SHPK phosphorylates Sedo to Sedo7P (Homo sapiens)


name: L-pentahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: H(+) + H2O + N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase] => N-hydroxy-L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: (R)-glycerate + ADP-alpha-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Homo sapiens)


name: (+)-minovincinine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-vincadifformine + O2 + reduced [NADPH--hemoprotein reductase]


name: GDP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosamine => GDP-beta-L-fucose + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine


name: Rsu-1 interacts with Pinch1 (Dictyostelium discoideum)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Saccharomyces cerevisiae)


name: a cytidine in mRNA + S-adenosyl-L-methionine => an N(3)-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: Re-integration of insulin receptor into plasma membrane (Sus scrofa)


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate = ectocarpin A + H2O


name: L1-FGFR cis-heterodimerization (Homo sapiens)


name: a fatty acid methyl ester + S-adenosyl-L-homocysteine => a fatty acid + S-adenosyl-L-methionine


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Danio rerio)


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Dictyostelium discoideum)


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Caenorhabditis elegans)


name: STAP2 recruits STAT3 to PTK6 (Homo sapiens)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Drosophila melanogaster)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Sus scrofa)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Schizosaccharomyces pombe)


name: ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate <=> AMP + diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Rattus norvegicus)


name: WWTR1 (TAZ) binds ZO-2 (TJP2) (Sus scrofa)


name: (S)-malate + UDP-N-acetyl-alpha-D-glucosamine = (S)-malyl N-acetyl-alpha-D-glucosaminide + H(+) + UDP


name: SALMs 1-3 bind to PSD-95 family members (Rattus norvegicus)


name: Release of GABA at the synapse (Sus scrofa)


name: Phosphorylated Cdc6 is exported from the nucleus (Sus scrofa)


name: PE is converted to PS by PTDSS2 (Plasmodium falciparum)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + UMP = (6S)-5,6,7,8-tetrahydrofolate + 5-methyl-UMP + NADP(+)


name: postsynaptic neurotransmitter receptor activity


name: NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Sus scrofa)


name: A + ergothioneine + H2O => 2-sulfenohercynine + AH2 + H(+)


name: SLC6A4 binds TCAs and SSRIs (Homo sapiens)


name: alpha,alpha-trehalose + hexadecanoyl-CoA => 2-O-hexadecanoyl-alpha,alpha-trehalose + CoA


name: NADP(+) + prostaglandin F2alpha => 15-oxoprostaglandin F2alpha + H(+) + NADPH


name: DHNTP is dephosphorylated by PTPS to PTHP (Rattus norvegicus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)


name: Exocytosis of azurophil granule lumen proteins (Homo sapiens)


name: DVL1 is ubiquitinated by HECW1 (Bos taurus)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Bos taurus)


name: DCC interacts with DIP13alpha (Rattus norvegicus)


name: FMNH2 + N-acetyl-S-methyl-L-cysteine + O2 = (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: 2 chloride(in) + K(+)(in) + Na(+)(in) => 2 chloride(out) + K(+)(out) + Na(+)(out)


name: CPTP transports C1P from plasma membrane to Golgi membrane (Caenorhabditis elegans)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Rattus norvegicus)


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Canis familiaris)


name: CHMP7 binds CC2D1B (Drosophila melanogaster)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Sus scrofa)


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Mus musculus)


name: (-)-menthol + H(+) + NADPH + O2 <=> 1,4-menthane-3,8-diol + H2O + NADP(+)


name: 2-methyl-cis-aconitate + H2O => (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate


name: (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase] = acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: GP1b signaling involves c-Src (Gallus gallus)


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Rattus norvegicus)


name: pro-beta-NGF homodimer transits to the golgi apparatus (Homo sapiens)


name: Caspase-8 processing within TLR3 complex (Homo sapiens)


name: ARFRP1 recruits ARL1 to the TGN (Gallus gallus)


name: linear 1,3-beta-D-glucan synthase activity


name: [(1->2)-beta-D-glucosyl](n)(in) + ATP + H2O = [(1->2)-beta-D-glucosyl](n)(out) + ADP + H(+) + phosphate


name: 9-cis-10'-apo-beta-carotenal + beta-ionone => 9-cis-beta-carotene + O2


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane (Canis familiaris)


name: eNoSC deacetylates histone H3 (Saccharomyces cerevisiae)


name: bromide + L-tyrosine + NADP(+) <=> 3-bromo-L-tyrosine + NADPH


name: cGMP is degraded by PDEs (Canis familiaris)


name: a diacylglycerol + H2O <=> a fatty acid + a monoacylglycerol + H(+)


name: isorhamnetin + S-adenosyl-L-methionine => 3',4'-O-dimethylquercetin + 2 H(+) + S-adenosyl-L-homocysteine


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Bos taurus)


name: gibberellin A12 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> gibberellin A15 + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H2O + N-acetyl-L-aspartyl-L-glutamate => L-glutamate + N-acetyl-L-aspartate


name: A + a 3-oxo-5beta-steroid <=> a 3-oxo-Delta(4)-steroid + AH2


name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 (Schizosaccharomyces pombe)


name: Phosphorylation of DLC2 by MAPK8 (Bos taurus)


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Sus scrofa)


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Homo sapiens)


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-heptanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl heptanoate + apo--[retinol-binding protein]


name: ADP + H(+) + O-phospho-L-seryl-[Goodpasture antigen-binding protein] => ATP + L-seryl-[Goodpasture antigen-binding protein]


name: (E)-3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA => (E)-3-(indol-3-yl)acryloyl-CoA + (R)-3-(indol-3-yl)lactate


name: trans-Golgi Network Lysosomal Vesicle Scission (Gallus gallus)


name: 2-oxoglutarate + 3-methyldodecanoyl-CoA + O2 => 2-hydroxy-3-methyldodecanoyl-CoA + CO2 + succinate


name: H2O + hexan-2-amine + NAD(+) => H(+) + hexan-2-one + NADH + NH4(+)


name: H(+) + NADH + phylloquinone <=> NAD(+) + phylloquinol


name: H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol = a fatty acid + H(+) + long chain 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Danio rerio)


name: 2-phenylethanol + benzoyl-CoA = CoA + phenethyl benzoate


name: corticosterone + NAD(+) <=> 11-dehydrocorticosterone + H(+) + NADH


name: 5beta-dihydroepitestosterone + NADP(+) => epitestosterone + H(+) + NADPH


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Rattus norvegicus)


name: CSF3R binds CSF3 dimer (Canis familiaris)


name: PLK2 phosphorylates CENPJ (Mus musculus)


name: 5beta-dihydrotestosterone + H(+) + NADPH <=> 5beta-androstane-3beta,17beta-diol + NADP(+)


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine => H(+) + kanamycin X + UDP


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Drosophila melanogaster)


name: a fatty acyl-CoA + hexadecasphinganine <=> CoA + H(+) + N-acylhexadecasphinganine


name: PLK1 hyperphosphorylates Condensin II complex (Caenorhabditis elegans)


name: D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose


name: NR1H2,3 binds the EEPD1 gene (Homo sapiens)


name: (E)-4-coumaroyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] <=> CoA + H(+) + myricetin 3-O-[(6-O-(E)-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: chlorophyllide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 7(1)-hydroxychlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: CO2 + phosphate + succinate + uridine-5'-aldehyde => 2-oxoglutarate + O2 + UMP


name: T1R1/T1R3 dimer is the umami taste receptor (Danio rerio)


name: H(+) + orotidine 5'-phosphate <=> CO2 + UMP


name: AFG3L2 degrades mitochondrial matrix proteins (Canis familiaris)


name: [amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ATP => [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + ADP


name: diphosphate + N(6)-[(R)-dihydrolipoyl]-5'-AMP => (R)-dihydrolipoate + ATP + H(+)


name: Interaction of SHP-1 or SHP-2 with phospho PD-1 (Homo sapiens)


name: Tenascins C, R, (X, N) bind lecticans (Gallus gallus)


name: a ganglioside Gal-GD1b (d18:1(4E)) + GDP-beta-L-fucose => a ganglioside Gal(Fuc)-GD1b (d18:1(4E)) + GDP + H(+)


name: a ganglioside GalNAc-GD1a (d18:1(4E)) + H(+) + UDP => a ganglioside GD1a (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-pyrethrolone <=> CoA + pyrethrin I


name: NEIL2 cleaves 5-OHU from damaged DNA (Sus scrofa)


name: PKC-delta translocates to plasma membrane (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate => diphosphate + valerena-4,7(11)-diene


name: Caspase-mediated cleavage of claspin (Bos taurus)


name: 2,5-dihydroxybenzoyl-CoA + H2O + NAD(+) => 2-hydroxybenzoyl-CoA + H(+) + NADH + O2


name: 2 H(+)(in) + H2 + ubiquinone-8 = 2 H(+)(out) + ubiquinol-8


name: CO2 + H(+) + nonanal + succinate + sulfate => 2-oxoglutarate + nonyl sufate + O2


name: ASICs bind STOML3, (STOM) (Rattus norvegicus)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Sus scrofa)


name: candesartan + UDP-alpha-D-glucuronate <=> candesartan-2-N-beta-D-glucuronide + UDP


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Mus musculus)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Gallus gallus)


name: L-cysteinyl-[SCAN] + S-nitroso-L-cysteinyl-[protein] => L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[SCAN]


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Homo sapiens)


name: H2O + O2 + spermine => 3-aminopropanal + H2O2 + spermidine


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Rattus norvegicus)


name: "galactan exo-1,6-beta-galactobiohydrolase (non-reducing end)"


name: cytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-methionine <=> 2'-O-methylcytidine(4) in tRNA(Gly)(GCC) + H(+) + S-adenosyl-L-homocysteine


name: a triacylglycerol + H2O <=> a 1,2-diacylglycerol + a fatty acid + H(+)


name: PCK1 phosphorylates OA to yield PEP (Sus scrofa)


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Homo sapiens)