name: beta-D-Gal-(1<->1')-Cer + CMP-N-acetyl-beta-neuraminate => CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide


name: Elastin degradation by MMP14 (Rattus norvegicus)


name: Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Rattus norvegicus)


name: Formation of VAF (virus-activated factor) complex (Homo sapiens)


name: 1-hexadecanoyl-2-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = (6Z,9Z,12Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: apulose + ATP => ADP + apulose 4-phosphate + H(+)


name: CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Drosophila melanogaster)


name: Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)


name: DSCAM/DSCAML1 homodimerization (Homo sapiens)


name: 2 juglone + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H(+)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Xenopus tropicalis)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Rattus norvegicus)


name: an inositol-1-phosphoceramide + H2O <=> 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)


name: Activation of conventional Protein Kinase C (Canis familiaris)


name: beta-alanine + urea => 3-guanidinopropanoate + H2O


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Sus scrofa)


name: (+)-guaia-6,9-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Mus musculus)


name: GAA hydrolyzes lysosomal glycogen (Schizosaccharomyces pombe)


name: Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa (Homo sapiens)


name: NADP(+) + UDP-beta-L-rhamnose => H(+) + NADPH + UDP-4-dehydro-beta-L-rhamnose


name: inhibitory MHC class I receptor activity


name: Translocation of PLC-gamma1 to PIP2 (Danio rerio)


name: methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Bos taurus)


name: CDO binds promyogenic cadherins (Sus scrofa)


name: a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin] => a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid + 8 oxidized 2[4Fe-4S]-[ferredoxin]


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Mus musculus)


name: RHOC binds effectors at the plasma membrane (Sus scrofa)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Bos taurus)


name: RFC dissociates after sliding clamp formation (Dictyostelium discoideum)


name: guanosine(in) + H(+)(in) => guanosine(out) + H(+)(out)


name: (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + oxidized [electron-transfer flavoprotein] + pentanoyl-CoA


name: FPGS-2 transforms THF to THFPG (Homo sapiens)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + 2 succinate => 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 O2


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate => 2 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Gallus gallus)


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: fructose 1,6-bisphosphate 1-phosphatase activity


name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Bos taurus)


name: Loading of acetylcholine in synaptic vesicles (Bos taurus)


name: ATP + diphthine-[translation elongation factor 2] + NH4(+) => AMP + diphosphate + diphthamide-[translation elongation factor 2] + H(+)


name: Release of acetylcholine at the synapse (Canis familiaris)


name: Active G alpha (q) binds RGS proteins (Homo sapiens)


name: RND1 binds effectors (Rattus norvegicus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Sus scrofa)


name: BTRC binds p-S344, 347 NFE2L2 (Sus scrofa)


name: 5alpha-androstan-3,17-dione + H(+) + NADPH => androsterone + NADP(+)


name: (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA + NADP(+)


name: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)


name: cytidine(32) in tRNA + S-adenosyl-L-methionine => 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: ent-kaur-16-en-19-al + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = ent-kaur-16-en-19-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a triacylglycerol + CoA => a 1,2-diacylglycerol + an acyl-CoA


name: H2O + octanoyl-[ACP] => H(+) + holo-[ACP] + octanoate


name: a 3-(all-trans-polyprenyl)benzene-1,2-diol + H2O + NADP(+) => a 2-all-trans-polyprenylphenol + H(+) + NADPH + O2


name: beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + H2O = D-glucose + N-octadecanoylsphing-4-enine


name: B3GNT5 transfers GlcNAc to LacCer (Drosophila melanogaster)


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Canis familiaris)


name: ATP + H2O + 4 Na(+)(in) <=> ADP + H(+) + 4 Na(+)(out) + phosphate


name: 8-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 8,20-dihydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) <=> H(+) + NADPH + testosterone


name: (9Z,12Z,15Z)-octadecatrienoate + O2 = (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate


name: RTC completes synthesis of the minus strand genomic RNA complement (Homo sapiens)


name: 2 alpha,alpha'-trehalose 6-mycolate => alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose


name: glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol (Mycobacterium tuberculosis)


name: Cleavage of Procaspase-7 by the apoptosome (Danio rerio)


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Canis familiaris)


name: thyroid-stimulating hormone receptor activity


name: AMP + an acyl-CoA + H(+) => an acyl-AMP + CoA


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Mus musculus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Xenopus tropicalis)


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Sus scrofa)


name: an anthocyanidin 3-O-beta-D-glucoside + malonyl-CoA = an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: Sustained activation of SRC kinase by SHP2 (Gallus gallus)


name: GTSE1 binds microtubule lattice in interphase cells (Mus musculus)


name: 4-hydroxybutanoyl-CoA + AMP + diphosphate => 4-hydroxybutanoate + ATP + CoA


name: an alk-2-enal + H(+) + NADPH => an n-alkanal + NADP(+)


name: (+)-epi-isozizaene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (R)-lipoate + GTP + H(+) => (R)-lipoyl-GMP + diphosphate


name: lactose + H2O => D-glucose + D-galactose (Bos taurus)


name: NCOA2(869-1464) binds KAT6A(1-1118) (Canis familiaris)


name: 2-oxoglutarate + O2 + octanoyl-CoA => 2-hydroxyoctanoyl-CoA + CO2 + succinate


name: NANP dephosphorylates Neu5Ac-9-P to Neu5Ac (Drosophila melanogaster)


name: 2-methyl-cis-aconitate + H2O => 2-methylcitrate


name: (2E,6E)-farnesyl diphosphate = diphosphate + germacrene C


name: PI is hydrolyzed to 2-acyl LPI by PLA2[13] (Homo sapiens)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Homo sapiens)


name: LIAS synthesizes lipoyl-GCSH (Gallus gallus)


name: CSNK1A1 and ADRBK1 dissociate from p-SMO dimer (Drosophila melanogaster)


name: a 4,5-saturated-(2E)-enoyl-CoA + NADP(+) <=> a (2E,4E)-dienoyl-CoA + H(+) + NADPH


name: H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + N-succinyl-L-glutamate + NADH


name: ME1 tetramer decarboxylates MAL to PYR (Homo sapiens)


name: 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA => (9Z)-octadecenoyl-CoA + 1-O-hexadecylglycerol


name: NAD(+) + resolvin E1 => 18-oxo-resolvin E1 + H(+) + NADH


name: Assembly of gap junction plaques (Homo sapiens)


name: butan-2-one + H(+) + NADH + O2 <=> 1-hydroxy-2-butanone + H2O + NAD(+)


name: 1,2-diacyl-sn-glycero-3-phospho-N-acyl-L-serine + H2O <=> 1-acyl-sn-glycero-3-phospho-N-acyl-L-serine + a fatty acid + H(+)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Bos taurus)


name: D-erythrose 4-phosphate + D-xylulose 5-phosphate = beta-D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: FLVCR1-1 transports heme from cytosol to extracellular region (Bos taurus)


name: CO2 + phosphate + phosphoenolpyruvate => diphosphate + oxaloacetate


name: ADP + beta-D-fructose 6-phosphate => AMP + beta-D-fructose 1,6-bisphosphate + H(+)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Gallus gallus)


name: GDP + H(+) + N-acetyl-D-glucosamine 6-phosphate => GTP + N-acetyl-D-glucosamine


name: 7,8-dihydromethanopterin + AH2 => 5,6,7,8-tetrahydromethanopterin + A


name: HSF1 trimer translocates to the nucleus (Sus scrofa)


name: (11Z,14Z,17Z)-eicosatrienamide + H2O = (11Z,14Z,17Z)-eicosatrienoate + NH4(+)


name: (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NADP(+) = 4-methylcatechol + CO2 + NADPH


name: FGAM + ATP => AIR + ADP + Pi (Canis familiaris)


name: Endocytosis of SARS-CoV-2 Virion (Homo sapiens)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Drosophila melanogaster)


name: 2,3-dihydroxybenzoyl-5'-AMP + diphosphate => 2,3-dihydroxybenzoate + ATP + H(+)


name: 2-oxoadipate + CoA + NAD(+) => CO2 + glutaryl-CoA + NADH


name: SLMB binds phosphorylated cytosolic PER, facilitating its ubiquitination (Drosophila melanogaster)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Bos taurus)


name: miR-92b binds 3'UTR of NLK mRNA (Homo sapiens)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphate <=> 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate


name: PTPN22 dephosphorylates ZAP70 (Homo sapiens)


name: PIAS2,3,4 SUMOylate RORA with SUMO1 (Bos taurus)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Gallus gallus)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Rattus norvegicus)


name: ESTG binds ESR1:chaperone complex (Sus scrofa)


name: Loading of acetylcholine in synaptic vesicles (Danio rerio)


name: p-Y7-CLEC1B dimer:PDPN binds SYK (Rattus norvegicus)


name: (2E)-nonenoyl-CoA + FADH2 => FAD + H(+) + nonanoyl-CoA


name: 2-oxoaldehyde + H2O + NADP(+) <=> a 2-oxocarboxylate + 2 H(+) + NADPH


name: Proinsulin translocates from the endoplasmic reticulum to the Golgi (Bos taurus)


name: 3-sulfino-L-alanine(out) + L-aspartate(in) <=> 3-sulfino-L-alanine(in) + L-aspartate(out)


name: 2-oxoglutarate + UDP-4-amino-4-deoxy-beta-L-arabinose = L-glutamate + UDP-beta-L-threo-pentopyranos-4-ulose


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Rattus norvegicus)


name: REG3A,REG3G binds bacterial peptidoglycan (Rattus norvegicus)


name: BPHL hydrolyses VACV to ACV (Sus scrofa)


name: PTK2 is recruited to methylated ESR1 (Bos taurus)


name: ATP:coenzyme F420 adenylyltransferase activity


name: STAT1 and STAT3 dimers translocate to the nucleus (Caenorhabditis elegans)


name: Phosphorylation of ZAP-70 by Lck (Homo sapiens)


name: Interleukin-5 is a homodimer (Canis familiaris)


name: PP1 dephosphorylates phosphorylated TIM (Drosophila melanogaster)


name: Cleavage of Procaspase‑9 to caspase‑9 (Rattus norvegicus)


name: 2 Na(+)(out) + scyllo-inositol(out) = 2 Na(+)(in) + scyllo-inositol(in)


name: coenzyme M + methyl-Co(III)-[methylamine-specific corrinoid protein] => Co(I)-[methylamine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Drosophila melanogaster)


name: DDX41 ubiquitination by TRIM21 (Mus musculus)


name: arginine + H2O => ornithine + urea [ARG2] (Sus scrofa)


name: GGCT transforms gGluCys to OPRO (Xenopus tropicalis)


name: 1,9-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: cyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucuronate = cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + H(+) + UDP


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+)


name: 3,4,6-trichlorocatechol + O2 = (2Z,4E)-2,3,5-trichloromuconate + H(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex (Homo sapiens)


name: H(+) + momilactone A + NADH => 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide + NAD(+)


name: 5beta-pregnan-3,20-dione + H(+) + NADPH => 20alpha-hydroxy-5beta-pregnan-3-one + NADP(+)


name: ATP + gamma-L-glutamyl-L-glutamyl-[tubulin] + L-glutamate <=> ADP + H(+) + L-glutamyl-gamma-L-glutamyl-L-glutamyl-[tubulin] + phosphate


name: SCF-FBXL18 ubiquitinates FBXL7 (Rattus norvegicus)


name: (2S)-3-sulfolactaldehyde + D-sedoheptulose 7-phosphate => 6-deoxy-6-sulfo-D-fructose + D-erythrose 4-phosphate


name: Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex (Homo sapiens)


name: ESR binds STRN (Drosophila melanogaster)


name: TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III (Bos taurus)


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Drosophila melanogaster)


name: STAT4 binds p-Y-IL23R in IL23:IL23 receptor (Canis familiaris)


name: NAD(+) + shikimate => 3-dehydroshikimate + H(+) + NADH


name: Retromer recycles WLS to the Golgi (Drosophila melanogaster)


name: an aliphatic alcohol + H(+) + hexadecanoate => H2O + hexadecanoate ester


name: SCNN channels transport extracellular Na+ to cytosol (Rattus norvegicus)


name: (S)-malate(in) + malonate(out) => (S)-malate(out) + malonate(in)


name: Interaction of Tie2 and Grb14 (Canis familiaris)


name: 3-hydroxy-L-kynurenine + pyruvate = H2O + L-alanine + xanthurenate


name: H(+) + NADH + O2 + propene => 1,2-epoxypropane + H2O + NAD(+)


name: a ganglioside GalGal-GD1b (d18:1(4E)) + H(+) + UDP => a ganglioside Gal-GD1b (d18:1(4E)) + UDP-alpha-D-galactose


name: Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription (Homo sapiens)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Caenorhabditis elegans)


name: allocholate + lithocholoyl-CoA = allocholoyl-CoA + lithocholate


name: RCHY1 monoubiquitinates POLH (Danio rerio)


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Sus scrofa)


name: UGCG transfers glucose to ceramide (Mus musculus)


name: 2 H(+) + H2O + N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase] => L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: H2O + L-arginine + NAD(+) = 5-guanidino-2-oxopentanoate + H(+) + NADH + NH4(+)


name: an N-acylsphing-4-enine + phosphate => an N-acylsphing-4-enine 1-phosphate + H2O


name: 4-amino-3-all-trans-hexaprenylbenzoate + diphosphate => 4-aminobenzoate + all-trans-hexaprenyl diphosphate


name: (Z)-2-methylureidoacrylate + H2O <=> (Z)-2-methylaminoacrylate + carbamate + H(+)


name: Interleukin-27 translocates from the ER lumen to the extracellular region (Bos taurus)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Xenopus tropicalis)


name: TBC1D10A (EPI64) binds ARF6:GTP (Sus scrofa)


name: Conversion of glyoxylate to oxalate (Xenopus tropicalis)


name: 2 L-dopa + O2 <=> 2 H2O + 2 L-dopaquinone


name: 5-phosphomethyl-dUMP in DNA + glycine = 5-N(alpha)-glycyl-dTMP in DNA + phosphate


name: 3-oxohexacosanoyl-CoA + H(+) + NADH = (3R)-hydroxyhexacosanoyl-CoA + NAD(+)


name: SUCLG1/G2 cleaves succinyl-CoA (Bos taurus)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Saccharomyces cerevisiae)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Gallus gallus)


name: RHOH binds effectors at the plasma membrane (Bos taurus)


name: menaquinone-7 + succinate => fumarate + menaquinol-7


name: [collagen]-L-lysyl-N-S-L-methionyl-[collagen] + bromide + H(+) + H2O => hypobromite + L-lysyl-[collagen] + L-methionyl-[collagen]


name: a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + H(+) + UDP => a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose


name: cis-(homo)3aconitate + H2O => (2R,3S)-iso(homo)3citrate


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Mus musculus)


name: ADRA1A,B,D bind ADR,NAd (Canis familiaris)


name: L-histidine(in) + Na(+)(in) <=> L-histidine(out) + Na(+)(out)


name: Contactin-1 (CNTN1) binds NOTCH1 (Homo sapiens)


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Saccharomyces cerevisiae)


name: CD4 binds Interleukin-16 (Canis familiaris)


name: (9Z)-tetradecenoate(out) + ATP(in) + CoA(in) + H(+)(out) <=> (9Z)-tetradecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: diphosphate + H2O + Na(+)(in) = H(+) + Na(+)(out) + 2 phosphate


name: FeHM dissociates from MetHb (Gallus gallus)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Canis familiaris)


name: Caspase 3-mediated cleavage of PKC delta (Caenorhabditis elegans)


name: 12-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 12-hydroxyoctadecanoate + H(+)


name: Phosphorylation of APC component of the destruction complex (Rattus norvegicus)


name: alpha-maltose 6'-phosphate + H2O => D-maltose + phosphate


name: Aquaporin-4 passively transports water out of cell (Sus scrofa)


name: choline + H(+) + sphing-4-enine 1-phosphate => H2O + sphing-4-enine-phosphocholine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 7-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 12-methyloctadecanoate + ATP + CoA => 12-methyloctadecanoyl-CoA + AMP + diphosphate


name: HSF1 trimer translocates to the nucleus (Homo sapiens)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Mus musculus)


name: Gq-BTK complex dissociates to Active BTK and Gq (Gallus gallus)


name: FGAM + ATP => AIR + ADP + Pi (Drosophila melanogaster)


name: H(+) + juvenile hormone III carboxylate + methanol => H2O + juvenile hormone III


name: D-phenylalanyl-tRNA(Phe) + H2O <=> D-phenylalanine + H(+) + tRNA(Phe)


name: acetyl-CoA + ergosta-5,7,22,24(28)-tetraen-3beta-ol <=> CoA + ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate


name: a (2E)-2-fatty-enoyl-AMP + diphosphate => a (2E)-enoyl fatty acid + ATP + H(+)


name: ALDH7A1 oxidises BETALD to BET (Dictyostelium discoideum)


name: (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Homo sapiens)


name: Dissociation of cytosolic HSF1:HSP90 complex (Schizosaccharomyces pombe)


name: a 2'-deoxyribonucleoside 5'-diphosphate + dTDP => a 2'-deoxyribonucleoside 5'-phosphate + dTTP


name: SH pentamer transports K+ (Homo sapiens)


name: Formation of pre-mRNPs (Caenorhabditis elegans)


name: RFC dissociates after sliding clamp formation (Mus musculus)


name: GUCYs converts GTP to cGMP (Mus musculus)


name: Phosphorylation of E proteins by p38 MAPK (Homo sapiens)


name: 1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol <=> an alkyl cinnamate + beta-D-glucose


name: L-cysteine + S-sulfanyl-L-cysteine = L-alanine + S-disulfanyl-L-cysteine


name: AcCho is hydrolyzed to Cho and acetate by ACHE (Danio rerio)


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Drosophila melanogaster)


name: KIR2DS1 interacting with HLA-C group 2 (Cw4) (Rattus norvegicus)


name: SARS virus buds into ERGIC lumen (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Homo sapiens)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Dictyostelium discoideum)


name: Histone H3.3 deposition at telomere (Homo sapiens)


name: type 2 metabotropic GABA receptor binding


name: factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) (Bos taurus)


name: 6,8-dimethyl-6,7-didehydroergoline + H(+) + NADH => festuclavine + NAD(+)


name: (6E)-8-hydroxygeraniol + NAD(+) = (6E)-8-oxogeraniol + H(+) + NADH


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O => 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)


name: histone H3K122 acetyltransferase activity


name: A + Delta(1)-dihydrotestosterone + H2O = 17beta-hydroxyandrostan-1,3-dione + AH2


name: [thioredoxin]-dithiol + L-methionine (S)-S-oxide => [thioredoxin]-disulfide + H2O + L-methionine


name: 11-oxo-beta-amyrin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 11alpha-hydroxy-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase]


name: OSCAR binds collagen and SP-D (Xenopus tropicalis)


name: SUMOylation of HDAC2 with SUMO1 (Schizosaccharomyces pombe)


name: Beclin-1 complex phosphorylates PtdIns (Sus scrofa)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Canis familiaris)


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Danio rerio)


name: Coumarin is 7-hydroxylated by CYP2A13 (Rattus norvegicus)


name: TP53 binds STK11 and NUAK1 (Canis familiaris)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)


name: ANGPTL8 binds ANGPTL3 (Canis familiaris)


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Xenopus tropicalis)


name: (R)-pantolactone + A => 2-dehydropantolactone + AH2


name: ATP + D-maltose(out) + H2O = ADP + D-maltose(in) + H(+) + phosphate


name: Collagen type II degradation by MMP15 (Gallus gallus)


name: ABP1 binds SHANK proteins (Mus musculus)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Sus scrofa)


name: (Z)-4'-methoxydehydrocyclopeptine + CO2 + H2O + succinate => (-)-4'-methoxycyclopeptine + 2-oxoglutarate + O2


name: HLA-B specific inhibitory MHC class I receptor activity


name: CoA + kaempferol 3-O-(6-O-malonyl-beta-D-glucoside) => kaempferol 3-O-beta-D-glucoside + malonyl-CoA


name: (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate => (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O


name: glutaryl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-glutaryl-L-lysyl-[protein]


name: adenosine(1408) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(1408) in 16S rRNA + S-adenosyl-L-homocysteine


name: Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Gallus gallus)


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: 2-oxobutanoate + H(+) + NADH => (2S)-hydroxybutanoate + NAD(+)


name: 3-deoxy-alpha-D-manno-oct-2-ulosonate <=> D-arabinose + pyruvate


name: adenosine 5'-phosphosulfate + H2O => AMP + 2 H(+) + sulfate


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Homo sapiens)


name: PTK6 phosphorylates KHDRBS1 (Xenopus tropicalis)


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Dictyostelium discoideum)


name: 3'-phosphoadenylyl sulfate + glycodeoxycholate = 3alpha-sulfoglycodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: 2-methylbutanoyl-CoA + hexan-1-ol => CoA + hexyl 2-methylbutanoate


name: ATP + chloramphenicol(in) + H2O <=> ADP + chloramphenicol(out) + H(+) + phosphate


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Sus scrofa)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Homo sapiens)


name: (1S,5R)-carveol + NADP(+) => (R)-carvone + H(+) + NADPH


name: Activation of RAC1 by VAV2/3 (Homo sapiens)


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Dictyostelium discoideum)


name: 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al => 2 H(+) + O2 + pentalen-13-ol + 2 reduced [2Fe-2S]-[ferredoxin]


name: (S)-2-ureidoglycine + glyoxylate => glycine + N-carbamoyl-2-oxoglycine


name: p-STAT1 binds p-STAT3 (Caenorhabditis elegans)


name: pyridoxine + UDP-alpha-D-glucose <=> 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP


name: 2-methyl-2-(methylamino)propanoate(out) + chloride(out) + 2 Na(+)(out) => 2-methyl-2-(methylamino)propanoate(in) + chloride(in) + 2 Na(+)(in)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Gallus gallus)


name: 3'-dephospho-CoA + ATP <=> ADP + CoA + H(+)


name: beta-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + ursodeoxycholate


name: CDP-1L-myo-inositol + diphosphate => 1D-myo-inositol 3-phosphate + CTP + H(+)


name: NADP(+) + rhazimol <=> 2 H(+) + NADPH + rhazimal


name: ADP + H(+) + O-phospho-L-seryl-[tyrosine-3-monooxygenase] => ATP + L-seryl-[tyrosine-3-monooxygenase]


name: Cargo-carrying vesicles bud from the TGN (Caenorhabditis elegans)


name: PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate + 5,7-dihydroxy-4-methylphthalide => 4-farnesyl-3,5-dihydroxy-6-methylphthalide + diphosphate


name: PTK2 is recruited to methylated ESR1 (Caenorhabditis elegans)


name: 7,12-dioxo-lithocholate + H(+) + NADPH => 3alpha,7beta-dihydroxy-12-oxo-5beta-cholan-24-oate + NADP(+)


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Xenopus tropicalis)


name: CMP-N-acetyl-beta-neuraminate + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] = 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + CMP + H(+)


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Rattus norvegicus)


name: p38MAPK phosphorylates MSK1 (Schizosaccharomyces pombe)


name: glutathione(out) + taurocholate(in) => glutathione(in) + taurocholate(out)


name: H2O + lovastatin <=> (S)-2-methylbutanoate + H(+) + monacolin J


name: adenosine(1832) in 18S rRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(1832) in 18S rRNA + S-adenosyl-L-homocysteine


name: KHK dimer phosphorylates Fru to Fru 1-P (Bos taurus)


name: EDNRA,EDNRB bind EDNs (Rattus norvegicus)


name: A + asnovolin A + H2O => AH2 + asnovolin J + O2


name: CERT1-2 complex binds ceramide (Bos taurus)


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Homo sapiens)


name: Activated FGFR4 phosphorylates FRS3 (Rattus norvegicus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Gallus gallus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 = prostaglandin G2


name: p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane (Rattus norvegicus)


name: 7-dehydrodesmosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 5alpha-cholesta-7,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: adenosine(in) + H(+)(in) <=> adenosine(out) + H(+)(out)


name: (1S,8aR)-delta-cadinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 2 glutathione amide + NAD(+) <=> glutathione amide disulfide + H(+) + NADH


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Bos taurus)


name: Dimerization of phosphorylated IRF3/IRF7 (Bos taurus)


name: ERBB4s80:STAT5A complex translocates to the nucleus (Sus scrofa)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Xenopus tropicalis)


name: L-pentahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Saccharomyces cerevisiae)


name: HNF1A-dependent synthesis of HNF4G protein (Homo sapiens)


name: bromochloromethane + H2O <=> bromide + chloride + formaldehyde + 2 H(+)


name: Activation of WASP and N-WASP by CDC42 (Homo sapiens)


name: (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine => ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine


name: Factor D cleaves C3(H2O)-bound Factor B (Xenopus tropicalis)


name: Activated FGFR3 binds PLCG1 (Danio rerio)


name: (9Z)-octadecenoyl-CoA + decan-1-ol = 1-O-decyl-(9Z)-octadecenoate + CoA


name: ECHS1 hydrates methacrylyl-CoA (Drosophila melanogaster)


name: ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Sus scrofa)


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Caenorhabditis elegans)


name: glutarate(in) + glycocholate(out) <=> glutarate(out) + glycocholate(in)


name: 5S-HpETE is dehydrated to LTA4 by ALOX5 (Rattus norvegicus)


name: lanosterol + O2 + reduced [NADPH--hemoprotein reductase] = 32-hydroxylanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-galactaro-1,5-lactone + H(+) + NADH => beta-D-galacturonate + NAD(+)


name: (9Z,12Z)-octadecadienoate + O2 <=> 9-hydroperoxy-(10E,12Z)-octadecadienoate


name: (Z)-beta-ocimene + diphosphate => (2E)-geranyl diphosphate


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Sus scrofa)


name: G-protein alpha subunit is inactivated (Mus musculus)


name: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) <=> benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH


name: FAD + H(+) + H2O + lithocholate <=> chenodeoxycholate + FADH2


name: H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP => diphosphate + UDP-N-acetyl-alpha-D-glucosamine


name: IFN alpha/beta binds to IFNAR2 (Rattus norvegicus)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP-alpha-D-glucose = 2 H(+) + ternatin C5 + UDP


name: MHC Class I interacts with CD160 (Canis familiaris)


name: Activated FGFR3:p-SHC1 binds GRB2:SOS1 (Drosophila melanogaster)


name: SARS-CoV-2 8 binds class I MHC (Homo sapiens)


name: PDE5A dimer binds PDE5A inhibitors (Drosophila melanogaster)


name: an N,N-dimethylornithine lipid + S-adenosyl-L-methionine = an N,N,N-trimethylornithine lipid + H(+) + S-adenosyl-L-homocysteine


name: ATF2 acetylates histone H2B, H4 (Gallus gallus)


name: bilirubin IXalpha bis-beta-D-glucuronoside(out) => bilirubin IXalpha bis-beta-D-glucuronoside(in)


name: IL21 receptor JAK phosphorylation (Mus musculus)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Schizosaccharomyces pombe)


name: guanine + queuosine(34) in tRNA(Asp) => guanosine(34) in tRNA(Asp) + queuine


name: Interaction of integrin alphaIIbbeta3 with Fibronectin (Caenorhabditis elegans)


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Drosophila melanogaster)


name: H(+) + rebeccamycin + S-adenosyl-L-homocysteine => 4'-demethylrebeccamycin + S-adenosyl-L-methionine


name: GGT hydrolyses RCTR1 to RCTR2 (Homo sapiens)


name: L-serine + NAD(+) = aminoacetaldehyde + CO2 + NADH


name: eNoSC dimethylates histone H3 at lysine-9 (Canis familiaris)


name: H(+) + N-hydroxy-L-aspartate + NADPH + O2 = H2O + N,N-dihydroxy-L-aspartate + NADP(+)


name: Formation of PPAT dimers (Gallus gallus)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Homo sapiens)


name: WLS is endocytosed to the early endosome (Gallus gallus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: a 5-hydroxy anthocyanidin + UDP-alpha-D-glucose <=> an anthocyanin 5-O-beta-D-glucoside + H(+) + UDP


name: (2R,9Z)-2-hydroperoxyoctadecenoate => (9Z)-octadecenoate + O2


name: RAC2 binds effectors at the ER membrane (Xenopus tropicalis)


name: PCSK1 hydrolyzes proGIP to GIP (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Gallus gallus)


name: alpha-D-mannose 1-phosphate + D-mannose => beta-D-mannopyranosyl-(1->2)-D-mannopyranose + phosphate


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Bos taurus)


name: acetaldehyde + H(+) + pyruvate <=> acetoin + CO2


name: 15-methylhexadecasphinganine 1-phosphate = 13-methyltetradecanal + phosphoethanolamine


name: polyamine transmembrane transporter activity


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-(4R)-hydroxysphinganine <=> a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine


name: STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Rattus norvegicus)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HTR3A antagonists bind HTR3A pentamer (Sus scrofa)


name: a ganglioside GD3 + H2O => a ganglioside GM3 + N-acetylneuraminate


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Mus musculus)


name: a ganglioside GM1 (d18:1(4E)) + H2O <=> a ganglioside GM2 (d18:1(4E)) + D-galactose


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Canis familiaris)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)


name: ADH5 oxidises S-HMGSH to S-FGSH (Canis familiaris)


name: apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + ATP + biotin = AMP + diphosphate + H(+) + holo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]


name: Tachykinin receptor 1 (NK1) binds to substance P (Sus scrofa)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Xenopus tropicalis)


name: GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1 (Homo sapiens)


name: Reinsertion of L1 into the plasma membrane (Mus musculus)


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Rattus norvegicus)


name: ADP-alpha-D-glucose + D-fructose <=> ADP + H(+) + sucrose


name: fumarate + H(+) + nitrite => 2-nitrobutanedioate


name: Activated FGFR1 phosphorylates FRS2 (Drosophila melanogaster)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Dictyostelium discoideum)


name: XYLB phosphorylates D-xylulose (Canis familiaris)


name: Docking of Mature Replication Dependent Histone mRNA with the NPC (Gallus gallus)


name: 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine => beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O


name: DOLPP1 dephosphorylates DOLDP to DOLP (Xenopus tropicalis)


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Bos taurus)


name: RHOG translocates to the ER membrane (Mus musculus)


name: 18-HEPE + O2 => (5S)-hydroperoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate


name: p-Y705-STAT3 binds p-Y693-STAT4 (Sus scrofa)


name: D-fructose + D-glucose => D-glucono-1,5-lactone + D-sorbitol


name: GAR + 10-Formyl-THF => FGAR + THF (Saccharomyces cerevisiae)


name: MAPK1 phosphorylates SOX10 (Canis familiaris)


name: HMG CoA => acetoacetic acid + acetyl CoA (Danio rerio)


name: NAD(+) + trans-4-hydroxycyclohexane-1-carboxylate = 4-oxocyclohexane-1-carboxylate + H(+) + NADH


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Bos taurus)


name: PIN1 binds p-S345-NCF1 (Xenopus tropicalis)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 => (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-eicosatrienoate


name: PTPRZ dephosphorylates ligand-bound ALK dimers (Bos taurus)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Drosophila melanogaster)


name: 2-oxoglutarate + an aromatic L-alpha-amino acid <=> an aromatic oxo-acid + L-glutamate


name: 3'-phosphoadenylyl sulfate + a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine = adenosine 3',5'-bisphosphate + H(+) + N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine


name: ATP + oxaloacetate => ADP + CO2 + phosphoenolpyruvate


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Homo sapiens)


name: ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus (Bos taurus)


name: PEX19:class I PMP binds PEX3 (Gallus gallus)


name: RNF111 ubiquitinates SUMOylated XPC (Mus musculus)


name: AH2 + hercynyl-SeGlcNAc selenoxide => 2-acetamidoglucal + A + H2O + selenoneine


name: CYLD deubiquitinates NEMO (Mus musculus)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Xenopus tropicalis)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Canis familiaris)


name: ADP + H(+) + streptomycin 6-phosphate => ATP + streptomycin


name: lactoferrin transmembrane transporter activity


name: IL34 dimer binds CSF1R (Xenopus tropicalis)


name: a dolichyl beta-D-glucosyl phosphate + chenodeoxycholate = a dolichyl phosphate + beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H(+)


name: phenylacetonitrile + sulfate + sulfur => (Z)-phenyl-N-(sulfonatooxy)methanimidothioate


name: biphenyl-2,2',3-triol + H(+) + NADH + O2 = biphenyl-2,2',3,3'-tetraol + H2O + NAD(+)


name: cyclohexan-1,2-dione + H2O => 6-oxohexanoate + H(+)


name: L-aspartate + O2 = H2O2 + iminosuccinate


name: 3-(imidazol-5-yl)pyruvate + H2O2 + NH4(+) => D-histidine + H2O + O2


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Xenopus tropicalis)


name: Clustering of Integrin alphaIIb beta3 complexes (Gallus gallus)


name: 1'-[1-acyl-2-(9-hydroxy-(10E,12Z)-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1,2-diacyl-sn-glycero-3-phospho]-glycerol + H2O <=> 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + 9-hydroxy-(10E,12Z)-octadecadienoate + H(+)


name: ribostamycin + UDP-N-acetyl-alpha-D-glucosamine => 2'''-acetyl-6'''-hydroxyneomycin C + H(+) + UDP


name: Phosphorylated KHDRBS1 translocates to the cytosol (Xenopus tropicalis)


name: p-S MAPK6 phosphorylates NCOA3 (Mus musculus)


name: 4-hydroxybenzoate + H(+) + NADH + O2 => 3,4-dihydroxybenzoate + H2O + NAD(+)


name: ATM phosphorylates RBBP8 (Schizosaccharomyces pombe)


name: di-(9Z)-octadecenoylglycerol + H2O => (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+)


name: OMA1 hydrolyses OPA1 (Xenopus tropicalis)


name: BCHE hydrolyzes ASA- (Rattus norvegicus)


name: Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)


name: ADD1:ADD2 binds DMTN (Dictyostelium discoideum)


name: glycine(in) + L-alanine(out) => glycine(out) + L-alanine(in)


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Bos taurus)


name: 15-hydroxypentadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA => 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: Excess homocysteine yields homolanthionine and H2S (Canis familiaris)


name: H2O + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] = N(alpha)-acetyl-L-methionine + N-terminal L-glutamyl-[protein]


name: 6-deoxyerythronolide B + 6 CO2 + 7 CoA + H2O + 6 NADP(+) => 6 (S)-methylmalonyl-CoA + 12 H(+) + 6 NADPH + propanoyl-CoA


name: beta-D-glucosylceramide + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H(+) + UDP


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Rattus norvegicus)


name: HTR1A binds 5HT (Drosophila melanogaster)


name: Receptor CCR6 binds CCL20 ligand (Sus scrofa)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Rattus norvegicus)


name: chloride(out) + 2 hydrogencarbonate(in) + Li(+)(in) => chloride(in) + 2 hydrogencarbonate(out) + Li(+)(out)


name: TASP1 cleaves KMT2A (Xenopus tropicalis)


name: p-STAT1:p-STAT4 translocates to the nucleus (Caenorhabditis elegans)


name: (E)-feruloyl-CoA + ADP + phosphate => (E)-ferulate + ATP + CoA


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Mus musculus)


name: ATP + di-trans,octa-cis-undecaprenol => ADP + di-trans,octa-cis-undecaprenyl phosphate + H(+)


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Dictyostelium discoideum)


name: [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + H2O = [CysO sulfur-carrier protein]-C-terminal Gly-Gly + H(+) + L-cysteine


name: "[CysO sulfur-carrier protein]-S-L-cysteine hydrolase"


name: protein C-terminal leucine carboxyl O-methyltransferase activity


name: TAT aminates HPP (Caenorhabditis elegans)


name: acetyl-CoA + 6 H(+) + holo-[ACP] + 6 malonyl-CoA => 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] + 6 CO2 + 7 CoA


name: AJUBA facilitates AURKA autophosphorylation (Rattus norvegicus)


name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: coenzyme M + methyl-Co(III)-[glycine betaine-specific corrinoid protein] <=> Co(I)-[glycine betaine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: D-glyceraldehyde + H(+) + NADH = glycerol + NAD(+)


name: butan-2-one + H(+) + NADH + O2 => 1-hydroxy-2-butanone + H2O + NAD(+)


name: an anthocyanidin + H(+) + UDP-alpha-D-glucose = an anthocyanidin 3-O-beta-D-glucoside + UDP


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Rattus norvegicus)


name: Disassociation of Telomerase RNP and the Chromosome End (Homo sapiens)


name: IL1 receptor antagonist protein binds Interleukin 1 receptors (Mus musculus)


name: (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + 2 glutathione => (17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + glutathione disulfide + H2O


name: 21-hydroxyprogesterone + H(+) + NADPH => 5beta-dihydrodeoxycorticosterone + NADP(+)


name: SMURF1/2 ubiquitinates PRICKLE1 (Rattus norvegicus)


name: 1-propanol + NADP(+) = H(+) + NADPH + propanal


name: (-)-yatein + 2-oxoglutarate + O2 = (-)-deoxypodophyllotoxin + CO2 + H2O + succinate


name: IRAK1 binds to MYD88 within the IL1R complex (Canis familiaris)


name: POLZ elongates POLI-incorporated dNMP (Rattus norvegicus)


name: (1'S,5'S)-averufin + NADPH + O2 => 1'-hydroxyversicolorone + H2O + NADP(+)


name: 1-heptadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-heptadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: PGM2:Mg2+ isomerises R1P to R5P (Plasmodium falciparum)


name: A + a 3-oxo-Delta(4)-steroid <=> a 3-oxo-Delta(1,4)-steroid + AH2


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Canis familiaris)


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Drosophila melanogaster)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Drosophila melanogaster)


name: Deubiquitinated PTEN translocates to the cytosol (Sus scrofa)


name: 5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 2-iminoacetate + 5'-deoxyadenosine + 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + H(+) + L-methionine


name: 9-hydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => hexadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: PF4 gene transcription is stimulated by RUNX1:CBFB (Homo sapiens)


name: PKCdelta phosphorylates HuR (Gallus gallus)


name: Expression of PLTP regulated by NR1H2 or NR1H3 (Homo sapiens)


name: ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Sus scrofa)


name: (E)-5-(methylsulfanyl)pentanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => L-dihomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Mus musculus)


name: 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O <=> 5alpha-cholestane-3beta,5,6beta-triol


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O = (-)-geosmin + acetone


name: Cleavage of thymine by TDG glycosylase (Schizosaccharomyces pombe)


name: 2 H(+) + hexacosanedioate + NADH => 26-oxohexacosanoate + H2O + NAD(+)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Canis familiaris)


name: H(+) + malonate + urea => 3-oxo-3-ureidopropanoate + H2O


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Sus scrofa)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Plasmodium falciparum)


name: GSTO1 dimer reduces methylarsonate to methylarsonite (Canis familiaris)


name: a 5'-end FAD-phospho-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + FMN + 2 H(+)


name: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacylglycerol => a 1-acyl-sn-glycero-3-phosphoethanolamine + a triacylglycerol


name: RHOV binds effectors at the plasma membrane (Canis familiaris)


name: H(+) + heptanoyl-CoA + malonyl-[ACP] <=> 3-oxononanoyl-[ACP] + CO2 + CoA


name: di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate => (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate


name: (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate + 7 diphosphate => (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Canis familiaris)


name: Delta(9)-tetrahydrocannabinolate + H(+) => CO2 + Delta(9)-tetrahydrocannabinol


name: CYTH proteins stimulate ARF1 GTPase activity (Schizosaccharomyces pombe)


name: D-glutamate + H2O + NAD(+) => 2-oxoglutarate + H(+) + NADH + NH4(+)


name: histone H3K4me/H3K4me2/H3K4me3 demethylase activity


name: H(+) + L-citrulline + phosphate => carbamoyl phosphate + L-ornithine


name: (11Z)-octadecenoyl-CoA + H2O => (11Z)-octadecenoate + CoA + H(+)


name: (2E,6E)-farnesol + ATP => (2E,6E)-farnesyl phosphate + ADP + H(+)


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Gallus gallus)


name: 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + H(+) + UDP


name: 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 <=> CO2 + grixazone B + 4 H2O


name: Excess cysteine yields lanthionine and H2S (Drosophila melanogaster)


name: Expression of LEUTX in the embryo (Homo sapiens)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Mus musculus)


name: a D-aminoacyl-tRNA + H2O => a D-alpha-amino acid + a tRNA + H(+)


name: GAB1 phosphorylation by EGFR kinase (Canis familiaris)


name: H2O + Xaa-L-Pro dipeptide = an L-alpha-amino acid + L-proline


name: Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Mus musculus)


name: Cleavage of DFF45 (224) by caspase-3 (Xenopus tropicalis)


name: hydrogen cyanide + L-cysteine <=> 3-cyano-L-alanine + H(+) + hydrogen sulfide


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 => (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: TPX2 promotes AURKA autophosphorylation (Homo sapiens)


name: Release of platelet secretory granule components (Drosophila melanogaster)


name: CoA + NAD(+) + propanal <=> H(+) + NADH + propanoyl-CoA


name: an N-acyl-L-homoserine lactone + H2O = an N-acyl-L-homoserine + H(+)


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Homo sapiens)


name: a monoacylglycerol + ATP = ADP + H(+) + monoacyl-sn-glycero-3-phosphate


name: 4 H(+) + 2 O2 + pentalenene + 4 reduced [2Fe-2S]-[ferredoxin] <=> 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al


name: 1-O-hexadecyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+) => 1-O-hexadecyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH


name: WNT5A binds FZD and ROR receptors (Rattus norvegicus)


name: formaldehyde + glutathione => S-(hydroxymethyl)glutathione


name: (5E)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,5E)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: Endosomal TLRs pass through the Golgi (Homo sapiens)


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Canis familiaris)


name: factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer (Gallus gallus)


name: aurachin C epoxide + H2O + NAD(+) => aurachin C + H(+) + NADH + O2


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Mus musculus)


name: Casein kinase II phosphorylates PTEN (Rattus norvegicus)


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Bos taurus)


name: RHOC translocates to the endoplasmic reticulum membrane (Mus musculus)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Canis familiaris)


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Homo sapiens)


name: 1,7-dimethylxanthine + S-adenosyl-L-methionine = caffeine + H(+) + S-adenosyl-L-homocysteine


name: (S)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH


name: Na+/H+ exchanger transport (at cell membrane) (Gallus gallus)


name: 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2


name: H(+) + NADH + O2 + quinolin-2-ol = H2O + NAD(+) + quinoline-2,8-diol


name: ADP + Ag(+)(out) + H(+) + phosphate => Ag(+)(in) + ATP + H2O


name: ADP-D-ribose + phosphate => ADP-alpha-D-ribose 1''-phosphate + H2O


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: WWP2 ubiquitinates NOTCH3 (Mus musculus)


name: H(+) + NADH + O2 + toluene = 4-methylphenol + H2O + NAD(+)


name: H2O + N-benzylformamide <=> benzylamine + formate


name: (1R,5S)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase]


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Canis familiaris)


name: 4-nitrocatechol + H(+) + NAD(+) + nitrite => 1,4-dinitrobenzene + NADH + O2


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Xenopus tropicalis)


name: 4'''-demalonylsalvianin + malonyl-CoA <=> CoA + salvianin


name: HBEGF-bound EGFR forms a heterodimer with GPNMB (Mus musculus)


name: L-phenylalanine(out) + S-methylmercury-L-cysteine(in) <=> L-phenylalanine(in) + S-methylmercury-L-cysteine(out)


name: TCR binds self-lipid-based antigen via CD1 (Gallus gallus)


name: chloride(out) + D-methionine(out) + 2 Na(+)(out) = chloride(in) + D-methionine(in) + 2 Na(+)(in)


name: RHOGEF2 binds to RHO1:GDP complex at the plasma membrane (Drosophila melanogaster)


name: Phosphorylated STATs are released (Gallus gallus)


name: ALDH7A1 oxidises BETALD to BET (Canis familiaris)


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)


name: 4-methyl-5-nitrocatechol + NADH + O2 = 2-hydroxy-5-methylquinone + H(+) + H2O + NAD(+) + nitrite


name: dATP + H2O => 2'-deoxyadenosine + H(+) + triphosphate


name: KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose (Homo sapiens)


name: sulfur compound transmembrane transporter activity


name: p-SHC1 binds integrin alpha5beta1:fibronectin (Homo sapiens)


name: H2O + L-methionine => 2-oxobutanoate + methanethiol + NH4(+)


name: benzoate + H(+) + NADH + O2 <=> (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: HRH1 binds HRH1 inverse agonists (Caenorhabditis elegans)


name: p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Homo sapiens)


name: 2-(9Z-octadecenoyl)-3-hexadecanoyl-sn-glycerol + H(+) + hexadecanoate => 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3B (GRIN3B) (Homo sapiens)


name: MTA is cleaved and phosphorylated (Caenorhabditis elegans)


name: 2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] <=> 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: H2O + indole-3-acetaldehyde + O2 <=> (indol-3-yl)acetate + H(+) + H2O2


name: Release of the SLBP independent Histone mRNA from the NPC (Mus musculus)


name: acetaldehyde + H(+) + phosphate => H2O + phosphonoacetaldehyde


name: NADP(+) + pyridine 3-methanol = H(+) + NADPH + pyridine-3-carbaldehyde


name: (2E,13Z)-docosadienoyl-CoA + H(+) + NADPH <=> (13Z)-docosenoyl-CoA + NADP(+)


name: 2 (S)-lactate(in) + prostaglandin E3(out) = 2 (S)-lactate(out) + prostaglandin E3(in)


name: MAOA:FAD deaminates DA to DOPAC (Homo sapiens)


name: Translocation of YAP1 to the nucleus (Gallus gallus)


name: Binding of the MCC complex to the APC/C complex (Dictyostelium discoideum)


name: FFAR1:FFAR1 ligands activate Gq (Homo sapiens)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)


name: (R)-3-hydroxy-2-methylpropanoate + NAD(+) => (R)-2-methyl-3-oxopropanoate + H(+) + NADH


name: SERPING1 variant is not secreted (Homo sapiens)


name: (2E)-decenedioyl-CoA + H2O = (3S)-hydroxydecanedioyl-CoA


name: Phosphorylation of PIP2 to PIP3 by PI3K (Gallus gallus)


name: BRF1 Complex recruits RNA degradation activities (Mus musculus)


name: ATP + N-(acetyl)-sphing-4-enine => ADP + H(+) + N-(acetyl)-sphing-4-enine-1-phosphate


name: an N-(acyl)-sphingosylphosphocholine(in) <=> an N-(acyl)-sphingosylphosphocholine(out)


name: RP2:ARL3:GDP:UNC119B dissociates (Mus musculus)


name: Hydrolysis of PC to PA by PLD (Xenopus tropicalis)


name: SGTA binds mislocalized membrane protein (Danio rerio)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Bos taurus)


name: (2R,3R)-dihydrokaempferol + 2-oxoglutarate + O2 = CO2 + H(+) + H2O + kaempferol + succinate


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H(+) + NADPH = (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: apo-Transferrin dissociates from the receptor complex (Mus musculus)


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine


name: H(+) + N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: SCF(SKP2) complex binds RUNX2 (Sus scrofa)


name: pH-gated monoatomic ion channel activity


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Mus musculus)


name: NUDT16 hydrolyses IDP to IMP (Bos taurus)


name: (9Z)-hexadecenoyl-CoA + AH2 + O2 = (9Z,12Z)-hexadecadienoyl-CoA + A + 2 H2O


name: Formation of the Spliceosomal Bact complex (Mus musculus)


name: NFE2 binds the beta globin locus control region (Sus scrofa)


name: p-S303,307-HSF1 binds YWHAE (14-3-3) (Mus musculus)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Mus musculus)


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Homo sapiens)


name: 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Caenorhabditis elegans)


name: glyoxylate + H2O + propanoyl-CoA <=> 2-hydroxyglutarate + CoA + H(+)


name: Latent TGF-beta-1 binds integrins (Homo sapiens)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)


name: PREDL:ALB dissociates (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H(+) + sn-glycerol 3-phosphocholine


name: HOMER binds SHANK proteins (Homo sapiens)


name: Caspase-mediated cleavage of occludin (Canis familiaris)


name: H2O + N(1)-acetylspermidine + O2 => 3-acetamidopropanal + H2O2 + putrescine


name: (indol-3-yl)acetate + ATP + L-lysine = ADP + H(+) + N(6)-[(indole-3-yl)acetyl]-L-lysine + phosphate


name: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively (Rattus norvegicus)


name: Cleavage of ethenoadenine by MPG glycosylase (Xenopus tropicalis)


name: L-Glutamine transport into neurons (Rattus norvegicus)


name: D-maltotriose + O2 => D-maltotriono-1,5-lactone + H2O2


name: ACLY tetramer transforms CIT to Ac-CoA (Sus scrofa)


name: ethylamine + N-isopropylammelide => H(+) + H2O + hydroxyatrazine


name: Caspase-mediated cleavage of Rock-1 (Drosophila melanogaster)


name: PP2A dephosphorylates KSR1 (Mus musculus)


name: FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 (Homo sapiens)


name: CoA + H(+) + N-(13Z-docosenoyl)-sphing-4-enine => (13Z)-docosenoyl-CoA + sphing-4-enine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-dodecanoyl-sn-glycero-3-phosphocholine = 1-dodecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: Mcm2-7 is phosphorylated by DDK (Homo sapiens)


name: 2-oxoglutarate + D-lysine = 6-amino-2-oxohexanoate + L-glutamate


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Sus scrofa)


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Sus scrofa)


name: A + H2O + quinoline => AH2 + quinolin-2(1H)-one


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Gallus gallus)


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Danio rerio)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Danio rerio)


name: HMGB1 release from cells (Saccharomyces cerevisiae)


name: PIAS2-2 SUMOylates SUZ12 with SUMO1 (Sus scrofa)


name: 4 (R)-3-phenyllactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine <=> 8 AMP + 8 diphosphate + 8 H(+) + PF1022B + 4 S-adenosyl-L-homocysteine


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate => 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Bos taurus)


name: CoA + NAD(+) + propanal => H(+) + NADH + propanoyl-CoA


name: 3-oxosphinganine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoyl-3-oxosphinganine


name: Noradrenaline is converted to adrenaline (Mus musculus)


name: guanosine(34) in tRNA(Tyr) + queuine <=> guanine + queuosine(34) in tRNA(Tyr)


name: CCNG2 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) (Homo sapiens)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Drosophila melanogaster)


name: MAPK1 phosphorylates SOX10 (Xenopus tropicalis)


name: (6S,9R)-vomifoliol + NAD(+) <=> (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH


name: acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein]


name: an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP-alpha-D-glucose = an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside + H(+) + UDP


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Caenorhabditis elegans)


name: 2-acyl LPG is acylated to PG by LPGAT (Danio rerio)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Homo sapiens)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Bos taurus)


name: beta-D-galactosyl-(1<->1)-sphing-4-enine + H2O = D-galactose + sphing-4-enine


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Canis familiaris)


name: Dynein motors transport misfolded proteins (Homo sapiens)


name: FPR2 binds FPR2 ligands (Xenopus tropicalis)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Canis familiaris)


name: 5-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 5-hydroxy-octadecanoate + H(+)


name: MIR150 microRNA binds 3'UTR of NOTCH3 mRNA (Homo sapiens)


name: diphosphate + manool => (+)-copalyl diphosphate + H2O


name: ADP(in) + dATP(out) => ADP(out) + dATP(in)


name: (9Z)-tetradecenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(11Z)-hexadecenoyl-CoA + CO2 + CoA


name: RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Mus musculus)


name: H(+) + N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine => L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine


name: PAAP-A proteolyzes IGF:IGFBP4 (Sus scrofa)


name: MTMR12 binds MTM1 (Schizosaccharomyces pombe)


name: ADP + ADP <=> AMP + ATP [AK2] (Canis familiaris)


name: (S)-piperazine-2-carboxamide + H2O = (S)-piperazine-2-carboxylate + NH4(+)


name: RAS:GTP binds RAL GDS proteins (Danio rerio)


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Rattus norvegicus)


name: (9Z)-hexadecenoate + 13-hydroxy-octadecanoate + H(+) => 13-(9Z-hexadecenoyloxy)-octadecanoate + H2O


name: (2E,6E,10E)-geranylgeranyl diphosphate + menadiol <=> diphosphate + menaquinol-4


name: Regeneration of eEF1A:GTP by eEF1B activity (Rattus norvegicus)


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Bos taurus)


name: PDCL releases folded G-beta from TRiC/CCT (Caenorhabditis elegans)


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Canis familiaris)


name: PIP3 recruits PDK1 and AKT to the membrane (Gallus gallus)


name: ADP + H(+) + L-glutamine(in) + phosphate => ATP + H2O + L-glutamine(out)


name: 1-pyrroline-5-carboxylate + 2 H(+) + NADH => L-proline + NAD(+)


name: NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Mus musculus)


name: [(2E,6E,10E)-geranylgeranyl]-L-cysteine + H2O + O2 <=> (2E,6E,10E)-geranylgeranial + H2O2 + L-cysteine


name: H2O + N(1)-acetylspermine + O2 <=> 3-aminopropanal + H2O2 + N(1)-acetylspermidine


name: diphosphate-purine nucleoside kinase activity


name: L-lysine + 2 S-adenosyl-L-methionine => 2 H(+) + N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine


name: β3-agonists bind ADRB3 (Drosophila melanogaster)


name: SLITs bind keratan sulfate (Gallus gallus)


name: (9Z)-octadecenoyl-CoA + 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate <=> (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: glyoxylate + L-glutamine = 2-oxoglutaramate + glycine


name: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + H(+) + NADH <=> (5S,6R,15S)-trihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Xenopus tropicalis)


name: cytidine(56) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(56) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: L-ornithine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) => L-ornithine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Xenopus tropicalis)


name: The 60S subunit joins the translation initiation complex  (Homo sapiens)


name: Furin cleaves pro-prothrombin to prothrombin (Gallus gallus)


name: ROS oxidize thioredoxin and activate MAP3K5 (Sus scrofa)


name: IRAK4-activated IRAK1 autophosphorylates (Mus musculus)


name: 6-azauridine 5'-phosphate + ADP + H(+) => 6-azauridine + ATP


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sarpagine => 10-deoxysarpagine + O2 + reduced [NADPH--hemoprotein reductase]


name: 5,10-methylenetetrahydromethanopterin + NAD(+) <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH


name: A1 and A3 receptors bind adenosine (Canis familiaris)


name: TP73 tetramer translocates to the nucleus (Mus musculus)


name: Extracellular processing of novel PDGFs (Xenopus tropicalis)


name: 5-phospho-alpha-D-ribose 1-diphosphate + orotate => diphosphate + orotidine 5'-phosphate


name: 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine + H2O = 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + choline + H(+)


name: (2E)-geranyl diphosphate = (1R,5R)-beta-pinene + diphosphate


name: a 1,2-diacyl-sn-glycerol + CTP => a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H(+)


name: H2O + thymidine 3'-phosphate = phosphate + thymidine


name: 3'-phosphoadenylyl sulfate + omega-hydroxy-beta-dihydromenaquinone-9 = adenosine 3',5'-bisphosphate + H(+) + omega-sulfo-beta-dihydromenaquinone-9


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: L1-FGFR cis-heterodimerization (Xenopus tropicalis)


name: Interaction of ABL1 with CDO complex (Homo sapiens)


name: 2 H(+) + 3 H2O + hydrogen sulfide + 3 oxidized coenzyme F420-(gamma-L-Glu)(n) => 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Danio rerio)


name: (S)-2-amino-6-oxohexanoate + H2O2 + NH4(+) => H2O + L-lysine + O2


name: N-hydroxy-L-tetrahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-tetrahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylsphinganine = a 1,2-diacyl-sn-glycerol + an N-acylsphinganine-1-phosphocholine


name: acetyl-CoA + D-glucosamine 6-phosphate = CoA + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: C30 botryococcene + S-adenosyl-L-methionine => 20-methyl-21,22-didehydro-20,21-dihydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: a dolichyl beta-D-mannosyl phosphate + H2O => a dolichyl phosphate + D-mannose + H(+)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Drosophila melanogaster)


name: RNF152 polyubiquitinates RRAGA (Xenopus tropicalis)


name: JMJD6 demethylates MeR3-histone H3 (Canis familiaris)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Caenorhabditis elegans)


name: dihydrochanoclavine-I aldehyde = 6,8-dimethyl-6,7-didehydroergoline + H2O


name: 2 1,2-benzoquinone + 2 H2O => 2 catechol + O2


name: L-glutamate(in) + L-thyroxine(out) = L-glutamate(out) + L-thyroxine(in)


name: L-arogenate + NADP(+) => CO2 + L-tyrosine + NADPH


name: acetone + 2 ATP + 3 H2O + hydrogencarbonate => acetoacetate + 2 AMP + 4 H(+) + 4 phosphate


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 24S,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O => 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + H(+) + phosphate


name: CUBN dissociates from 25(OH)D (Caenorhabditis elegans)


name: L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine <=> H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine


name: The bound receptor dimerizes (Mus musculus)


name: an omega-hydroxy fatty acid + O2 + reduced [NADPH--hemoprotein reductase] <=> an omega-oxo fatty acid + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Mus musculus)


name: L-arginine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) => L-arginine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: CK2 phosphorylates condensin I subunits (Rattus norvegicus)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate


name: ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Rattus norvegicus)


name: CHUK, IKBKB and IKBKG form IKK complex (Mus musculus)


name: CXXC1 and WDR82 bind SET1B complex (Homo sapiens)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Bos taurus)


name: SHC1 phosphorylation by ERBB2 heterodimers (Sus scrofa)


name: CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate


name: 3 H(+) + precorrin-4 + S-adenosyl-L-homocysteine => precorrin-3B + S-adenosyl-L-methionine


name: acetyl-CoA + N-terminal L-methionyl-L-lysyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein]


name: a 2,3-saturated acyl-CoA + FAD + H(+) <=> a (2E)-enoyl-CoA + FADH2


name: ST6GALNAC2 transfers sialic acid to Core 1 mucins (Sus scrofa)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Homo sapiens)


name: H(+) + NADP(+) + 2 reduced [adrenodoxin] => NADPH + 2 oxidized [adrenodoxin]


name: ADP + amicoumacin A 2-phosphate + H(+) => amicoumacin A + ATP


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Homo sapiens)


name: Cleaved KMT2A dimers translocate to the nucleus (Rattus norvegicus)


name: TRiC/CCT binds unfolded G-protein beta subunit (Saccharomyces cerevisiae)


name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate => D-erythrose 4-phosphate + H2O + phosphoenolpyruvate


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Homo sapiens)


name: AMP + diphosphate + GMP + 2 H(+) => ATP + NH4(+) + XMP


name: Luteinizing hormone is a heterodimer (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP


name: H(+) + NADH + O2 + toluene <=> (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: cytidine(in) + H(+)(in) = cytidine(out) + H(+)(out)


name: 2-dehydro-L-idonate + H(+) + NADPH => L-idonate + NADP(+)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-T-muurolol + diphosphate


name: H2O + L-alanine + NAD(+) <=> H(+) + NADH + NH4(+) + pyruvate


name: 3-demethylubiquinol-7 + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + ubiquinol-7


name: Active LTK phosphorylates IRS1 (Mus musculus)


name: Release of SEPT4 from mitochondria (Sus scrofa)


name: (S)-1-aminoethylphosphonate + acetyl-CoA => [(1S)-1-acetamidoethyl]phosphonate + CoA


name: JAK1-activated RAF1 phosphorylates MAPKs (Bos taurus)


name: p-STAT1:p-STAT4 translocates to the nucleus (Drosophila melanogaster)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Schizosaccharomyces pombe)


name: fumarate(out) + 3 H(+)(out) => fumarate(in) + 3 H(+)(in)


name: chloride(in) + L-serine(in) + 2 Na(+)(in) => chloride(out) + L-serine(out) + 2 Na(+)(out)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] => 17-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Bos taurus)


name: (24S)-hydroxycholesterol + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => (24S)-hydroxycholesterol 3-linoleoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + diphosphate + H(+) => a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + H2O


name: IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Bos taurus)


name: 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: aclacinomycin A + O2 <=> aclacinomycin Y + H2O2


name: PXLP-K333-GADL1 decarboxylates acidic AAs (Sus scrofa)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen (Mus musculus)


name: IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Gallus gallus)


name: gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Caenorhabditis elegans)


name: Follicle-stimulating hormone receptor can bind FSH (Danio rerio)


name: hexanal + hydrogen cyanide <=> (2S)-2-hydroxyheptanenitrile


name: (3R)-3-hydroxy-4-oxobutanoate + H2O + NADP(+) + trimethylamine => (R)-carnitine + H(+) + NADPH + O2


name: (25R)-3beta,4beta-dihydroxycholest-5-en-26-al + H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-3beta,4beta-dihydroxycholest-5-en-26-oate + H2O + 2 oxidized [adrenodoxin]


name: 2 H(+)(out) + H2O + menaquinone-8 + nitrite => 2 H(+)(in) + menaquinol-8 + nitrate


name: GRB2:GAB1 binds to phosphorylated EGFR (Mus musculus)


name: CHOL translocates from lysosome membrane to ER membrane (Saccharomyces cerevisiae)


name: Cytosolic folate export across the plasma membrane (Canis familiaris)


name: Caspase-8 and FLIP(L) processing at TNFR signaling complex (Gallus gallus)


name: S1P binds S1PR3 in response to E2 stimulation (Sus scrofa)


name: Autophosphorylation of chicken IRAK4 (Gallus gallus)


name: L-seryl-[protein] + N-acetyl-D-galactosamine => 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H2O


name: 3 CO2 + 4 CoA + 3 H2O + long-chain mycolipanoyl-[mycolipanoate synthase] + 6 NADP(+) => 3 (S)-methylmalonyl-CoA + a long-chain fatty acyl-CoA + 9 H(+) + holo-[mycolipanoate synthase] + 6 NADPH


name: Loss of SAR1B GTPase (Drosophila melanogaster)


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Canis familiaris)


name: beta-heptaprene + diphosphate => all-trans-heptaprenyl diphosphate


name: 3,3'-diiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) => 3,3'-diiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Caenorhabditis elegans)


name: AFG3L2 binds mitochondrial inner membrane proteins (Homo sapiens)


name: NOX2 generates superoxide from oxygen (Xenopus tropicalis)


name: DHFR2 reduces FOLA to DHF (Canis familiaris)


name: H(+) + keto-L-fructose + NADH => L-glucitol + NAD(+)


name: chloride(out) + dopamine(out) + Na(+)(out) = chloride(in) + dopamine(in) + Na(+)(in)


name: Association of DFF with alpha:beta importin (Mus musculus)


name: Defective HGSNAT does not acetylate Heparan sulfate chain(3) (Homo sapiens)


name: (+)-costunolide + H2O => 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+)


name: pyruvate + taurine => L-alanine + sulfoacetaldehyde


name: RPS6KA1-dependent phosphorylation of MITF-M (Homo sapiens)


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + H2O = H(+) + octadecanoate + sn-glycerol 3-phosphocholine


name: eNOS translocation from Golgi to Caveolae (Mus musculus)


name: a 12-hydroxyjasmonyl-L-alpha-amino acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => a jasmonyl-L-amino acid + O2 + reduced [NADPH--hemoprotein reductase]


name: benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Danio rerio)


name: (2E)-hexadecenoyl-CoA + H(+) + NADPH = hexadecanoyl-CoA + NADP(+)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Gallus gallus)


name: 6-aminopenicillanate + a carboxylate => a penicillin + H2O


name: beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + GDP-beta-L-fucose = beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-D-glucosamine + GDP + H(+)


name: Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 (Homo sapiens)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Danio rerio)


name: all-trans-hexaprenyl diphosphate => diphosphate + talaropentaene


name: argininosuccinate <=> fumarate + arginine (Drosophila melanogaster)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Canis familiaris)


name: 2 Na(+)(in) + tauroursodeoxycholate(in) => 2 Na(+)(out) + tauroursodeoxycholate(out)


name: a dicarboxylate(out) + dehydroepiandrosterone 3-sulfate(in) => a dicarboxylate(in) + dehydroepiandrosterone 3-sulfate(out)


name: H2O + indole-3-acetaldehyde + O2 => (indol-3-yl)acetate + H(+) + H2O2


name: snRNA 2'-O-ribose methylation guide activity


name: Autophosphorylation of PAK (Xenopus tropicalis)


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Canis familiaris)


name: (6E,10E)-geranyllinalool + O2 + reduced [NADPH--hemoprotein reductase] <=> (3E,7E)-4,8,12-trimethyltrideca 1,3,7,11-tetraene + but-3-en-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Neuroglobin binds oxygen (Caenorhabditis elegans)


name: Vamp8 associated secretory vesicle to plasma membrane transport (Sus scrofa)


name: Phosphorylation of DCC by Fyn (Bos taurus)


name: 3''-dehydroorientin <=> 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: 1D-chiro-inositol(out) + 2 Na(+)(out) => 1D-chiro-inositol(in) + 2 Na(+)(in)


name: ATP + carbamoyl phosphate + H2O + kanamycin A => 6''-O-carbamoylkanamycin A + AMP + diphosphate + H(+) + phosphate


name: TBC1D25 (OATL1) binds ATG8 homologues (Bos taurus)


name: holo-FDPS dimer binds NBPs (Homo sapiens)


name: N(7)-methyl-GTP + S-adenosyl-L-homocysteine => GTP + S-adenosyl-L-methionine


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Rattus norvegicus)


name: SIRPA binds SFTPA oligomer, SFTPD oligomer (Bos taurus)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Bos taurus)


name: Recruitment of POLB to oxidatively damaged AP site (Xenopus tropicalis)


name: TFAP2C translocates to the nucleus (Canis familiaris)


name: Formation of hydroxylysyl-pyrrole cross-links (Xenopus tropicalis)


name: HRH2 binds HRH2 antagonists (Drosophila melanogaster)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Homo sapiens)


name: L-ribulose 5-phosphate = D-xylulose 5-phosphate


name: TFIIH binds GG-NER site to form a verification complex (Mus musculus)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 <=> CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate


name: (2E)-geranyl diphosphate + H2O = (1S,2S,4R)-endo-fenchol + diphosphate


name: (2S)-2-phospholactate + GTP + H(+) = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate


name: FBXO5 gene expression is stimulated by E2F1 (Homo sapiens)


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Xenopus tropicalis)


name: H(+) + O-carbamoyl-L-serine <=> 2-aminoprop-2-enoate + CO2 + NH4(+)


name: 2-oxoglutarate + N(6)-methyladenosine in U6 snRNA + O2 = adenosine in U6 snRNA + CO2 + formaldehyde + succinate


name: Elongation of Extended Telomeric Chromosome End (Rattus norvegicus)


name: RGS proteins bind GNB5 and CCT/TRiC (Bos taurus)


name: 3'-AMP(in) + ADP(out) + H(+)(out) = 3'-AMP(out) + ADP(in) + H(+)(in)


name: adenosine 3',5'-bisphosphate + choline sulfate + H(+) => 3'-phosphoadenylyl sulfate + choline


name: SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Mus musculus)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Homo sapiens)


name: (4Z,15Z)-bilirubin IXalpha + NAD(+) => biliverdin IXalpha + H(+) + NADH


name: hyodeoxycholate + UDP-alpha-D-glucuronate <=> hyodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP


name: H(+) + hexadecanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-hexadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: CDP-DAG is converted to PI by CDIPT (Rattus norvegicus)


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: ATP + H(+) + octadecanoate = diphosphate + octadecanoyl-AMP


name: ALKBH2 binds alkylated DNA containing 1-meA (Homo sapiens)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Bos taurus)


name: 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Sus scrofa)


name: Calcineurin binds and dephosphorylates NFAT (Drosophila melanogaster)


name: SRXN1 reduces hyperoxidized PRDX1 dimer (Drosophila melanogaster)


name: ATP + di-trans,octa-cis-undecaprenol = ADP + di-trans,octa-cis-undecaprenyl phosphate + H(+)


name: "Linked to the hydrolysis of a nucleoside triphosphate"


name: NADP(+) + sn-glycerol 1-phosphate => dihydroxyacetone phosphate + H(+) + NADPH


name: glyoxylate + L-2-aminoadipate <=> 2-oxoadipate + glycine


name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate (Caenorhabditis elegans)


name: DDO oxidizes D-Asp to OA (Drosophila melanogaster)


name: (+)-epi-isozizaene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (5R)-albaflavenol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ferruginol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + pisiferate


name: Co(2+)(out) + 2 hydrogencarbonate(out) = Co(2+)(in) + 2 hydrogencarbonate(in)


name: Aquaporin-7 passively transports glycerol out of cell (Canis familiaris)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Mus musculus)


name: NT5C2 tetramer dephosphorylates RBV-MP (Dictyostelium discoideum)


name: epothilone D + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = epothilone B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: p-4Y-PLCG1 dissociates from activated FGFR2 mutants (Homo sapiens)


name: PLK1 hyperphosphorylates Condensin II complex (Dictyostelium discoideum)


name: (R)-glycerate + alpha-D-mannose 6-phosphate => (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate + H2O


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Bos taurus)


name: isodeoxycholate + NAD(+) => 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => beta-geranylfarnesene + diphosphate


name: Release of 40S and 60S subunits from the 80S ribosome  (Mus musculus)


name: 2 oxidized [2Fe-2S]-[ferredoxin] + primary fluorescent chlorophyll catabolite = 3 H(+) + red chlorophyll catabolite + 2 reduced [2Fe-2S]-[ferredoxin]


name: CES1 hydrolyses sacubitril to sacubitrilat (Sus scrofa)


name: SMAC (DIABLO) forms dimer (Homo sapiens)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Schizosaccharomyces pombe)


name: guanosine(2922) in 27S pre-rRNA + S-adenosyl-L-methionine => 2'-O-methylguanosine(2922) in 27S pre-rRNA + H(+) + S-adenosyl-L-homocysteine


name: formate + H(+) + menaquinone-8 <=> CO2 + menaquinol-8


name: (E)-coniferaldehyde + H2O + NAD(+) => (E)-ferulate + 2 H(+) + NADH


name: Na(+)(out) + xanthine(out) => Na(+)(in) + xanthine(in)


name: Formation of MHC II alpha beta heterodimer (Homo sapiens)


name: MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Homo sapiens)


name: chrysophanol-9-anthrone + O2 => chrysophanol + H2O


name: Caspase 8 or 10 recruitment to IPS1 complex followed by their dimerization (Gallus gallus)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Saccharomyces cerevisiae)


name: D-mannose(out) + H(+)(out) = D-mannose(in) + H(+)(in)


name: histone H3K27 acetyltransferase activity


name: EP300 acetylates histone H2A, H2B, H3, H4 (Xenopus tropicalis)


name: phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate (Rattus norvegicus)


name: H2O + N-acyl-L-aspartate => a carboxylate + L-aspartate


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] => (9R)-hydroxy-(10E,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: C3 convertases spontaneously dissociate (Xenopus tropicalis)


name: H(+) + prephenate = 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2


name: H(+) + NADPH + S-nitroso-CoA => NADP(+) + sulfinamide-CoA


name: H2O + N-(4-aminobutylpyrrolinium) ion + O2 = H2O2 + N-(4-oxobutylpyrrolinium) ion + NH4(+)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Gallus gallus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Gallus gallus)


name: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methyladenosine(1067) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Canis familiaris)


name: AH2 + S-adenosyl-L-methionine + UTP <=> 3'-deoxy-3',4'-didehydro-UTP + 5'-deoxyadenosine + A + H(+) + H2O + L-methionine


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Sus scrofa)


name: beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate


name: ATP + H(+)(in) + H2O + K(+)(out) = ADP + 2 H(+)(out) + K(+)(in) + phosphate


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)


name: D-alanyl-5'-AMP + holo-[D-alanyl-carrier protein] = AMP + D-alanyl-[D-alanyl-carrier protein] + H(+)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Bos taurus)


name: losartan + UDP-alpha-D-glucuronate <=> losartan-1-N-beta-D-glucuronide + UDP


name: SLC44A1 transports Cho from cytosol to mitochondrial matrix (Homo sapiens)


name: chloride(out) + L-isoleucine(out) + 2 Na(+)(out) = chloride(in) + L-isoleucine(in) + 2 Na(+)(in)


name: D-glucarate(in) + H(+)(in) => D-glucarate(out) + H(+)(out)


name: Resynthesis of excised residue by POLB (Homo sapiens)


name: SLC6A15-mediated amino acid uptake (Gallus gallus)


name: H2O + N(2)-(4-aminobutanoyl)-L-arginine <=> 4-aminobutanoate + L-arginine


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Bos taurus)


name: CO2 + NADPH + pyruvate => (S)-malate + NADP(+)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Sus scrofa)


name: 4 H2O + O2 + 4 sulfur = 6 H(+) + 2 hydrogen sulfide + 2 sulfite


name: 3-methoxybenzaldehyde + hydrogen cyanide <=> (2S)-2-hydroxy-2-(3-methoxyphenyl)acetonitrile


name: 26S proteasome degrades HIFalpha (Canis familiaris)


name: Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Xenopus tropicalis)


name: RAC2:GTP binds NOX2 complex (Mus musculus)


name: BRCA1 binds phosphorylated RBBP8 (Sus scrofa)


name: BAP1 binds BAP1-interacting complex (Mus musculus)


name: Activated FGFR2 phosphorylates FRS3 (Canis familiaris)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Rattus norvegicus)


name: (6S)-5,6,7,8-tetrahydrofolate + formaldehyde => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O


name: glutamine + H2O => glutamate + NH4+ [GLS] (Caenorhabditis elegans)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Bos taurus)


name: p62:MEKK3 binds to TRAF6 (Canis familiaris)


name: C3PO hydrolyzes cleaved passenger strand (Bos taurus)


name: succinate-CoA ligase (GDP-forming) activity


name: ATP + L-valine + tRNA(Val) <=> AMP + diphosphate + L-valyl-tRNA(Val)


name: Estrogen receptor binds IGF1R and SHC1 in response to estrogen (Sus scrofa)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Homo sapiens)


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + testosterone = 1alpha-hydroxytestosterone + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Xenopus tropicalis)


name: 26S proteasome degrades HIFalpha (Mus musculus)


name: Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) (Homo sapiens)


name: DNA-PKcs autophosphorylates (Canis familiaris)


name: MECP2 mutants P302R,K304E,K305R,R306C,(R306H) do not bind NCoR/SMRT complex (Homo sapiens)


name: E2F6:TFDP1/2 binds the E2F1 gene promoter (Homo sapiens)


name: H(+) + hyocholate 6-O-(beta-D-glucuronate) + UDP => hyocholate + UDP-alpha-D-glucuronate


name: (5S)-albaflavenol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => albaflavenone + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H(+) + menadione + NADH => menadiol + NAD(+)


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Homo sapiens)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Mus musculus)


name: TIMM23 SORT inserts proteins into inner membrane (Homo sapiens)


name: GDP-6-deoxy-alpha-D-talose + NAD(+) <=> GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADH


name: SRC phosphorylates PTK2 (Caenorhabditis elegans)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Homo sapiens)


name: 2'-N-acetylparomamine + H(+) + UDP => 2-deoxystreptamine + UDP-N-acetyl-alpha-D-glucosamine


name: USP14 deubiquitinates NLRC5 (Gallus gallus)


name: RET binds GFRA1,GFRA2 (Drosophila melanogaster)


name: ATP + L-seryl-[Goodpasture antigen-binding protein] <=> ADP + H(+) + O-phospho-L-seryl-[Goodpasture antigen-binding protein]


name: 1-aminocyclopropane-1-carboxylate + H(+) + S-methyl-5'-thioadenosine => S-adenosyl-L-methionine


name: hexadecanoyl-CoA + N-terminal L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester => CoA + H(+) + N-terminal N-hexadecanoyl-L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester


name: (2E)-geranyl diphosphate + diphosphate => dimethylallyl diphosphate + isopentenyl diphosphate


name: 5 H(+) + 4 H2O + 2 L-citrulline + 2 nitric oxide + 3 oxidized [flavodoxin] => 2 L-arginine + 4 O2 + 3 reduced [flavodoxin]


name: mitochondrion-endoplasmic reticulum membrane tether activity


name: Interaction of NCAM1 with GFRalpha-1 (Homo sapiens)


name: an omega-hydroxy-very-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase]


name: 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Bos taurus)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Sus scrofa)


name: an acyl phosphate + H2O => a carboxylate + H(+) + phosphate


name: Opioid dissociates from MOR (Homo sapiens)


name: Cytosolic DUSPs dephosphorylate MAPKs (Danio rerio)


name: (Z)-2-methylpropanal oxime => 2-methylpropanenitrile + H2O


name: F subunits form trimers at plasma membrane rafts (Homo sapiens)


name: L-fucose(out) + 2 Na(+)(out) <=> L-fucose(in) + 2 Na(+)(in)


name: a (7Z,10Z)-hexadecadienoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => a (7Z,10Z,13Z)-hexadecatrienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SUMOylation of NR3C1 (GR) with SUMO1 (Sus scrofa)


name: ornithine decarboxylase regulator activity


name: ALKBH3 in complex with ASCC1:ASCC2:ASCC3 binds alkylated DNA containing 1-etA (Homo sapiens)


name: GSDME (1-270) binds cardiolipin (Canis familiaris)


name: ATP binding to HSP90 triggers conformation change (Dictyostelium discoideum)


name: GST trimers transfer GS from GSH to luminal substrates (Bos taurus)


name: 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin] => a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin]


name: SORL1 transports APP(18-770) from endosome lumen to Golgi lumen (Homo sapiens)


name: DDR2 binds collagen type I, II, III, V, X fibrils (Rattus norvegicus)


name: SLC2A9 transports Fru, Glc, urate (Dictyostelium discoideum)


name: FA2H hydroxylates 1,2-saturated fatty acids (Caenorhabditis elegans)


name: A4GNT transfers GlcNAc to core 2 mucins (Homo sapiens)


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Rattus norvegicus)


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-mannosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-alpha-D-mannosaminouronate


name: Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation (Gallus gallus)


name: 2-oxoglutarate + GDP-alpha-D-perosamine <=> GDP-4-dehydro-alpha-D-rhamnose + L-glutamate


name: 1D-myo-inositol 5-phosphate + H2O = myo-inositol + phosphate


name: a (9Z)-hexadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (9Z,12E)-hexadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: S-adenosyl-L-methionine + scutellarein 7-methyl ether = H(+) + ladanein + S-adenosyl-L-homocysteine


name: D-glucose(out) + Na(+)(out) <=> D-glucose(in) + Na(+)(in)


name: an L-polyhomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = an L-N-hydroxypolyhomomethionine + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 dopamine + O2 = 2 dopamine quinone + 2 H2O


name: (2S)-2-amino-3-butenoate + H2O = 2-oxobutanoate + NH4(+)


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)


name: SOCS-1 and SOCS-3 binds to p-JAK2 (Bos taurus)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Drosophila melanogaster)


name: HS-GAGs translocate to the lysosome for degradation (Canis familiaris)


name: H(+) + phosphocholine + sphing-4-enine => H2O + sphing-4-enine-phosphocholine


name: mannose-1-phosphate guanylyltransferase (GTP) activity


name: Autophosphorylation of insulin receptor (Bos taurus)


name: Cytosolic PLK1 translocates to the nucleus (Mus musculus)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH (Homo sapiens)


name: Formation of MSH2:MSH3 Complex (Bos taurus)


name: (9Z)-octadecenoyl-CoA + H2O => adenosine 3',5'-bisphosphate + 2 H(+) + S-(9Z-octadecenoyl)-4'-phosphopantetheine


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Sus scrofa)


name: a (2R,3R)-dihydroflavonol + CO2 + succinate => 2-oxoglutarate + a (2S)-flavan-4-one + O2


name: NUMB:ITCH ubiquitinates GLI1 (Bos taurus)


name: PAK1 phosphorylates myosin phosphatase (Drosophila melanogaster)


name: AADAC deacetylates PHEN (Rattus norvegicus)


name: a globoside NOR1 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside NORint (d18:1(4E)) + H(+) + UDP


name: 11-cis-retinal + H2O + NAD(+) => 11-cis-retinoate + 2 H(+) + NADH


name: dodecanoyl-[ACP] + H2O <=> dodecanoate + H(+) + holo-[ACP]


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Sus scrofa)


name: desmosterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-25-epoxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of soluble VTN:C5b-C9  (Homo sapiens)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Mus musculus)


name: acetyl-CoA + L-glutamate 5-semialdehyde <=> CoA + H(+) + N-acetyl-L-glutamate 5-semialdehyde


name: PIPOX oxidises PPCA to P6C (Mus musculus)


name: (R)-S-lactoylglutathione + H2O <=> (R)-lactate + glutathione + H(+)


name: E2-mediated FOS gene expression (Homo sapiens)


name: 3-dehydro-4-O-phospho-L-erythronate + H(+) + NADH => 4-O-phospho-D-threonate + NAD(+)


name: an N-(fatty acyl)-L-methionine + H2O <=> a fatty acid + L-methionine


name: p-PKR dimer phosphorylates SPHK1 (Sus scrofa)


name: OPTN binds TBK1 within the activated TLR4 complex (Mus musculus)


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Mus musculus)


name: D-glucarate + 3 H(+) + NADH => D-glucurono-3,6-lactone + 2 H2O + NAD(+)


name: glyoxylate + N(omega),N(omega)-dimethyl-L-arginine => 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine


name: NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Drosophila melanogaster)


name: extracellular matrix structural constituent


name: CASP4, CASP5 cleave GSDMD (Gallus gallus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Canis familiaris)


name: Defective MTR does not transfer CH3 group from MeCbl to HCYS (Homo sapiens)


name: amino-acid betaine transmembrane transporter activity


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Canis familiaris)


name: (4R)-limonene + diphosphate => (2E)-geranyl diphosphate


name: indolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 3-hydroxyindolin-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: pseudouridine(746) in 23S rRNA => uridine(746) in 23S rRNA


name: ACVRL1 binds BMP9,BMP10 (Rattus norvegicus)


name: AAC1 imports a proton (Dictyostelium discoideum)


name: 25-hydroxyvitamin D2 + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,25-dihydroxyvitamin D2 + H2O + 2 oxidized [adrenodoxin]


name: CYTH proteins bind ARF1:GTP (Rattus norvegicus)


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)


name: HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Canis familiaris)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O => (9Z)-octadecenoate + 1,3-dihexadecanoylglycerol + H(+)


name: Synthesis of ALAS2 nascent polypeptide (Gallus gallus)


name: H2O + N(8)-acetylspermidine + O2 => 4-acetamidobutanal + H2O2 + propane-1,3-diamine


name: Formation of AT-AC C complex (Xenopus tropicalis)


name: (R)-carnitine + hexadecanedioyl-CoA = CoA + O-hexadecanedioyl-L-carnitine


name: alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: Spermine  => N-acetylated spermine (Bos taurus)


name: GLI3R translocates to the nucleus (Sus scrofa)


name: Removal of miRNA passenger strand (Bos taurus)


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Gallus gallus)


name: Estrogen stimulates dimerization of plasma membrane estrogen receptors (Rattus norvegicus)


name: (20S)-ginsenoside Rg3 + UDP-alpha-D-glucose <=> (20S)-ginsenoside Rd + H(+) + UDP


name: beta-D-fructose 6-phosphate + phosphate => beta-D-fructose 1,6-bisphosphate + H2O


name: SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Canis familiaris)


name: Phosphorylated MAPKs phosphorylate ATF-2 (Gallus gallus)


name: Myoglobin:oxygen dissociates (Sus scrofa)


name: 2-oxoglutarate + gibberellin A9 + O2 = CO2 + gibberellin A4 + succinate


name: D-erythrose 4-phosphate + H2O + phosphoenolpyruvate <=> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate


name: an N-acylsphing-4-enine + H2O => a fatty acid + sphing-4-enine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + N-hexadecanoyl-(4R)-hydroxysphinganine = a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine


name: SEC4C,D bind GOSR2 and STX5 (Dictyostelium discoideum)