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Includes DNA primase, DNA polymerase, DNA helicase, and other proteins."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1623212", "l": "plastid NADH dehydrogenase complex (plastoquinone)", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "NCIT:C164625", "l": "Start Chromosome Arm", "d": ["The chromosomal arm that contains the beginning of the range. (BRIDG)"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0106126", "l": "reservosome membrane", "d": ["The lipid bilayer surrounding a reservosome."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044317", "l": "rod spherule", "d": ["A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. 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SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754952", "l": "membrane-bound IgG", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0000148", "l": "1,3-beta-D-glucan synthase complex", "d": ["A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0106003", "l": "amyloid-beta complex", "d": ["Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. 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Soluble multimeric form is the main pathogenic species linked to Alzheimer's disease."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0098525", "l": "excitatory neuromuscular junction of somatic myotube", "d": ["A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2331619", "l": "Protoplasm of Type N enteroendocrine cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.858242952019168", "identifiers": [{"i": "GO:0043673", "l": "sexine", "d": ["The outer, sculptured layer of the exine, which lies above the nexine."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2610642", "l": "IL12B-IL12RB1-IL12RB2 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0521060", "l": "Ascus (fungus)", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821253", "l": "ATPase dependent transmembrane transport complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2611292", "l": "ITGA4-ITGB1-CD53 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2330705", "l": "Plasma membrane of lymphocyte", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120134", "l": "proximal portion of axoneme", "d": ["The portion of the axoneme that is close to the base of the cilium."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "72.472488299857119", "identifiers": [{"i": "GO:0005816", "l": "spindle pole body", "d": ["The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005723", "l": "alpha-heterochromatin", "d": ["A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3820698", "l": "viral capsid, turret", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325541", "l": "suberin network", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754261", "l": "ITGA3-ITGB1-CD63 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2612889", "l": "transcription factor TFIIIC2 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005633", "l": "ascus lipid droplet", "d": ["Any particle of coalesced lipids in an ascus or ascospore. 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An example of this component is found in Escherichia coli."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "MESH:D060527", "l": "Corneal Keratocytes", "d": [], "t": []}, {"i": "UMLS:C0229130", "l": "Structure of corneal corpuscle", "d": [], "t": []}, {"i": "SNOMEDCT:7884002", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166723", "l": "chitosome membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0170051", "l": "box C/D methylation guide scaRNP complex", "d": ["A ribonucleoprotein complex containing a small CB-specific RNA (scaRNA), with a short sequence motif (GU/UG wobble stem) for CB localization that is capable of methylation of target RNAs."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034996", "l": "RasGAP-Fyn-Lyn-Yes complex", "d": ["A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. 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Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1521178", "l": "2p14.1", "d": [], "t": []}, {"i": "NCIT:C25026", "l": "2p14.1", "d": ["A chromosome band present on 2p"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2324787", "l": "Protoplasm of enteroendocrine cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167335", "l": "site of polarized growth", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0005610", "l": "laminin-5 complex", "d": ["A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:1990249", "l": "nucleotide-excision repair, DNA damage recognition complex", "d": ["A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. 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SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1622067", "l": "gas vesicle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3896307", "l": "Rvs161p-Rvs167p complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167496", "l": "protein phosphatase 4 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2338671", "l": "Plasma membrane of Type P enteroendocrine cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990901", "l": "old cell pole", "d": ["The cell pole distal from the most recent cell division."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990329", "l": "IscS-TusA complex", "d": ["A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. 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This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824514", "l": "MUB1-RAD6-UBR2 ubiquitin ligase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230600", "l": "Intranuclear body, rod shaped", "d": [], "t": []}, {"i": "SNOMEDCT:89235004", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2336127", "l": "Nerve ending within Golgi tendon organ", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2752533", "l": "subplasmalemmal coating", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120228", "l": "outer dynein arm docking complex", "d": ["A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230713", "l": "Distinctive arrangement of cytoplasmic filaments", "d": [], "t": []}, {"i": "SNOMEDCT:11874005", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1180035", "l": "Lipid bilayer of wall of smooth endoplasmic reticulum vesicle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4689786", "l": "Kir6.1-SURx complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031526", "l": "brush border membrane", "d": ["The portion of the plasma membrane surrounding the brush border."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031604", "l": "nuclear proteasome core complex, alpha-subunit complex", "d": ["The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990326", "l": "collagen type XXVIII trimer", "d": ["A collagen homotrimer of alpha1(XXVIII) chains."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034977", "l": "ABIN2-NFKB1-MAP3K8 complex", "d": ["A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325735", "l": "retromer, cargo-selective complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0140364", "l": "GW body", "d": ["A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0048269", "l": "methionine adenosyltransferase complex", "d": ["A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990717", "l": "axonemal central bridge", "d": ["Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3548381", "l": "viral capsid, decoration", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.858242952019168", "identifiers": [{"i": "GO:0035839", "l": "non-growing cell tip", "d": ["A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "MESH:D000088242", "l": "Paraspeckles", "d": [], "t": []}, {"i": "UMLS:C1167109", "l": "Paraspeckles", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070618", "l": "Grb2-Sos complex", "d": ["A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3893394", "l": "pre-synaptic active zone component", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167295", "l": "respiratory chain complex III location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1514293", "l": "Pre-Condensed Chromosomes", "d": [], "t": []}, {"i": "NCIT:C13451", "l": "Pre-Condensed Chromosomes", "d": ["It refers to the chromosome status during the prophase of mitotic division. (NCI)"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.583239357332701", "identifiers": [{"i": "GO:0090533", "l": "cation-transporting ATPase complex", "d": ["Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1268445", "l": "Nucleus AND/OR associated structure", "d": [], "t": []}, {"i": "SNOMEDCT:108352009", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1180011", "l": "Membrane protein of endoplasmic reticulum cistern", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2612417", "l": "Sec translocation complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0098029", "l": "icosahedral viral capsid, spike", "d": ["A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4691113", "l": "pathogen inclusion lumen", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166732", "l": "clathrin coat of trans-Golgi network vesicle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.613571896142687", "identifiers": [{"i": "GO:0045171", "l": "intercellular bridge", "d": ["A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821307", "l": "host cell synaptic vesicle membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166738", "l": "trans-Golgi network transport vesicle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754987", "l": "monomeric IgA1 antibody", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990037", "l": "Lewy body core", "d": ["The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "UMLS:C1521404", "l": "4q28-q31", "d": [], "t": []}, {"i": "NCIT:C13918", "l": "4q28-q31", "d": ["A chromosome band present on 4q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0045098", "l": "type III intermediate filament", "d": ["A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230898", "l": "Collagen protofibrils", "d": [], "t": []}, {"i": "SNOMEDCT:17420003", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325623", "l": "proteasome regulatory particle (sensu Eukarya) location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821086", "l": "H-NS-Hha complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0032159", "l": "septin cap", "d": ["A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044308", "l": "axonal spine", "d": ["A spine that originates from the axon, usually from the initial segment."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754394", "l": "Kv4.2-KChIP1 channel complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2611212", "l": "IL4-IL4R-IL2RG complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0036362", "l": "ascus membrane", "d": ["A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824290", "l": "L-glutamate dehydrogenase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4235142", "l": "pituitary gonadotropin complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1180306", "l": "Inner dynein arm of axoneme of flagellum", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5162778", "l": "Dohle body | Blood | Hematology and Cell counts", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071061", "l": "alpha6-beta4 integrin-CD151 complex", "d": ["A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5451127", "l": "nuclear bridge", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:1902912", "l": "pyruvate kinase complex", "d": ["A protein complex which is capable of pyruvate kinase activity."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3896422", "l": "IRE1-RACK1-PP2A complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166894", "l": "mitochondrial large ribosomal subunit", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2323120", "l": "Cytoplasm of epithelial cell of nephron", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821287", "l": "transport vesicle lumen", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4327141", "l": "endopeptidase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2953980", "l": "Cytoskeleton of neural cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3549076", "l": "viral inner capsid", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167347", "l": "yeast-form cell wall", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4323128", "l": "Segment of photoreceptor", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4327250", "l": "intranuclear rod", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3546236", "l": "MVB-tubule complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3813159", "l": "periciliary membrane compartment", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C0596142", "l": "Autosome", "d": [], "t": []}, {"i": "NCIT:C32168", "l": "Autosome", "d": ["A chromosome not involved in sex determination. 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In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0098564", "l": "trans-Golgi network transport vesicle lumen", "d": ["The volume enclosed within the membrane of a trans-Golgi network transport vesicle."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754162", "l": "mammalian U12-type spliceosomal complex C", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3156028", "l": "SAGA DUBm complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "57.390599068896485", "identifiers": [{"i": "GO:0005929", "l": "cilium", "d": ["A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. 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The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2612458", "l": "very-low-density lipoprotein particle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0033102", "l": "acidocalcisome membrane", "d": ["The lipid bilayer surrounding an acidocalcisome."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.184450420133103", "identifiers": [{"i": "GO:0097441", "l": "basal dendrite", "d": ["A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "NCIT:C13716", "l": "Internal Ribosome Entry Site", "d": ["Internal ribosome entry site (IRES) is a translational cis-acting element that directs ribosomes to the start codon by a cap-independent mechanism. IRESs are usually about 450 nucleotides in length and were first identified in picornavirus RNAs. IRESs can fold into a stable secondary hairpin structure to be incompatible with efficient translation by ribosomal scanning. (NCI)"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0180022", "l": "RQC-trigger complex", "d": ["A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (Human TRIP4)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "72.078676747242454", "identifiers": [{"i": "GO:0019867", "l": "outer membrane", "d": ["The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0032998", "l": "Fc-epsilon receptor I complex", "d": ["A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "55.534857311150013", "identifiers": [{"i": "GO:0005739", "l": "mitochondrion", "d": ["A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. 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"t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "MESH:D055212", "l": "Photoreceptor Connecting Cilium", "d": [], "t": []}, {"i": "UMLS:C1819304", "l": "Photoreceptor Connecting Cilium", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824480", "l": "platelet-derived growth factor receptor-ligand complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2752177", "l": "neuronal cell body membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "72.078676747242454", "identifiers": [{"i": "GO:0071736", "l": "IgG immunoglobulin complex, circulating", "d": ["A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood 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"UMLS:C5450980", "l": "EGO-GSE complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2612852", "l": "methyltransferase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4327154", "l": "mitochondrial iron-sulfur cluster assembly complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1622069", "l": "SCF2 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1818833", "l": "myosin IX complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "73.223880475427393", "identifiers": [{"i": "GO:0005875", "l": "microtubule associated complex", "d": ["Any multimeric complex connected to a microtubule."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4325626", "l": "Palmitoyltransferase ERF2-SHR5 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0333748", "l": "Guarnieri bodies", "d": [], "t": []}, {"i": "SNOMEDCT:24645001", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0333777", "l": "Fingerprint bodies", "d": [], "t": []}, {"i": "SNOMEDCT:52114003", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097420", "l": "skein-like inclusion", "d": ["Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1621530", "l": "nuclear proteasome regulatory particle, base subcomplex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.184450420133103", "identifiers": [{"i": "UMLS:C1521555", "l": "6q12", "d": [], "t": []}, {"i": "NCIT:C25093", "l": "6q12", "d": 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[], "t": []}, {"i": "NCIT:C39632", "l": "4q31.1", "d": ["A chromosome band present on 4q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2336937", "l": "Set of cytoplasmic organelles of erythrocyte", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3549086", "l": "T=1 icosahedral viral capsid", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824386", "l": "taurine dioxygenase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1180360", "l": "Transverse part of intercalated disc", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3896423", "l": "IRE1alpha-RACK1-PP2A complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3269112", "l": "nuclear stress granule", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4236577", "l": "presynaptic cytoskeleton", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1516545", "l": "Chromosome Territory", "d": [], "t": []}, {"i": "NCIT:C13436", "l": "Chromosome Territory", "d": ["The physical volume occupied by a specific chromosome in the interphase nucleus. The territories from distinct chromosomes do not appear to overlap, preventing an intermingling of the decondensed chromatin. Relative to a nuclear landmark (e.g. nucleolus), chromosome territories appear to differ from cell to cell."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2247019", "l": "BRCA2-MAGE-D1 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167227", "l": "integrin complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0061802", "l": "anterior cell cortex", "d": ["The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "84.815870212838959", "identifiers": [{"i": "UMLS:C1520263", "l": "10p13", "d": [], "t": []}, {"i": "NCIT:C13479", "l": "10p13", "d": ["A chromosome band present on 10p"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4236711", "l": "endoplasmic reticulum subcompartment", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "66.914131229068573", "identifiers": [{"i": "UMLS:C0010851", "l": "Cytoskeletal Filaments", "d": [], "t": []}, {"i": "NCIT:C32603", "l": "Cytoskeleton Filament", "d": ["A group of three types of polymeric protein structures that impart shape to a cell and are involved in cellular motility, organelle localization and vesicular targeting."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "84.187358309157389", "identifiers": [{"i": "GO:0005791", "l": "rough endoplasmic reticulum", "d": ["The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3813157", "l": "messenger ribonucleoprotein complex location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230855", "l": "Transverse orientation of cristae of mitochondrion", "d": [], "t": []}, {"i": "SNOMEDCT:62518009", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0098983", "l": "symmetric, GABA-ergic, inhibitory synapse", "d": ["A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167402", "l": "intercellular bridge", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3159044", "l": "endonuclear canal", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034673", "l": "inhibin-betaglycan-ActRII complex", "d": ["A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2611201", "l": "integrin alphaIIb-beta3 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "73.943982515046912", "identifiers": [{"i": "GO:0042470", "l": "melanosome", "d": ["A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. 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Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "UMLS:C1520680", "l": "16p11.2-p11.1", "d": [], "t": []}, {"i": "NCIT:C24963", "l": "16p11.2-p11.1", "d": ["A chromosome band present on 16p"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0032116", "l": "SMC loading complex", "d": ["A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. 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Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2338846", "l": "Zone of cell body of spermatozoon", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4323158", "l": "Metaphase cell nucleus", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "85.510657888247053", "identifiers": [{"i": "GO:0005700", "l": "polytene chromosome", "d": ["A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0170010", "l": "nonsense-mediated decay complex", "d": ["A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0061793", "l": "chromatin lock complex", "d": ["A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0042564", "l": "NLS-dependent protein nuclear import complex", "d": ["A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "87.167921677548108", "identifiers": [{"i": "GO:0001533", "l": "cornified envelope", "d": ["A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0101002", "l": "ficolin-1-rich granule", "d": ["Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. 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It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034468", "l": "glycosome lumen", "d": ["The volume enclosed by the membrane of a glycosome."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4085353", "l": "flagellar pocket collar", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "69.566124125303446", "identifiers": [{"i": "GO:0030425", "l": "dendrite", "d": ["A neuron projection that has a short, tapering, morphology. 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An example of this component is found in Mus musculus."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2610231", "l": "polycystin complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824309", "l": "DnaB-DnaC-Rep-PriC complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3542979", "l": "Endoplasmic reticulum related to cell surface", "d": [], "t": []}, {"i": "SNOMEDCT:609332005", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166668", "l": "spectrin location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0043699", "l": "leucosome", "d": ["A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. 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Examples of this complex are found in Archaeal species."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "79.042693372152272", "identifiers": [{"i": "UMLS:C1268448", "l": "Cytokeratin filaments", "d": [], "t": []}, {"i": "NCIT:C13368", "l": "Keratin Filament", "d": ["A class of intermediate filaments that form a network within epithelial cells and anchor to desmosomes, thus imparting tensile strength to the tissue"], "t": []}, {"i": "SNOMEDCT:115569001", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754988", "l": "monomeric IgA2 antibody", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0099115", "l": "chromosome, subtelomeric region", "d": ["A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. 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It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0061845", "l": "neuron projection branch point", "d": ["The location where a secondary projection arises from a neuron projection."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097142", "l": "PUMA-BCL-2 complex", "d": ["A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824307", "l": "phi-X174-type preprimosome", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5379979", "l": "MutSgamma complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070466", "l": "alpha2-beta1 integrin-alpha3(VI) complex", "d": ["A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0045278", "l": "plasma membrane respiratory chain complex IV", "d": ["A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0099126", "l": "transforming growth factor beta complex", "d": ["A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0033620", "l": "Mei2 nuclear dot complex", "d": ["A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0060053", "l": "neurofilament cytoskeleton", "d": ["Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044612", "l": "nuclear pore linkers", "d": ["A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4329038", "l": "cleavage furrow leading edge", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "47.437878864984363", "identifiers": [{"i": "GO:0005911", "l": "cell-cell junction", "d": ["A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167000", "l": "plastid small ribosomal subunit", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0005825", "l": "half bridge of spindle pole body", "d": ["Structure adjacent to the plaques of the spindle pole body."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230827", "l": "Multivesicular body, internal vesicles", "d": [], "t": []}, {"i": "SNOMEDCT:621009", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2246609", "l": "DNA helicase A complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2248765", "l": "DNA polymerase III, proofreading complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3548790", "l": "half bridge of mitotic spindle pole body", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824306", "l": "DnaB-DnaC-DnaT-PriA-PriB complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0071747", "l": "IgA B cell receptor complex", "d": ["An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "69.96998809416209", "identifiers": [{"i": "GO:0032838", "l": "plasma membrane bounded cell projection cytoplasm", "d": ["All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3893357", "l": "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1623311", "l": "oral apparatus", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3546520", "l": "CHD-type complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1621412", "l": "contractile vacuolar membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2340314", "l": "Lipid bilayer of wall of trans Golgi cistern", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1622552", "l": "protein acetyltransferase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824591", "l": "USF1-USF2 heterodimer", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1660840", "l": "chromoplast inner membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3546706", "l": "dendritic branch point", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0035102", "l": "PRC1 complex", "d": ["A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2753501", "l": "interleukin-27 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0016011", "l": "dystroglycan complex", "d": ["A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4326870", "l": "apical plasma membrane urothelial plaque", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1820200", "l": "pigment granule", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167320", "l": "extrinsic component of membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034692", "l": "E.F.G complex", "d": ["A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. 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The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4690716", "l": "EDS1-PAD4 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:1902672", "l": "right anterior basal body", "d": ["Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230692", "l": "Melanosome, completely melanized", "d": [], "t": []}, {"i": "SNOMEDCT:88026008", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5451129", "l": "spore membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167507", "l": "serine-pyruvate aminotransferase, type 1 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "UMLS:C1520184", "l": "Xq13.1-q13.3", "d": [], "t": []}, {"i": "NCIT:C25140", "l": "Xq13.1-q13.3", "d": ["A chromosome band present on Xq"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044310", "l": "osmiophilic body", "d": ["A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3269086", "l": "BID-BCL-2 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "51.026485262539374", "identifiers": [{"i": "GO:0043005", "l": "neuron projection", "d": ["A prolongation or process extending from a nerve cell, e.g. an axon or dendrite."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3546209", "l": "autotransporter system complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "76.554670414377497", "identifiers": [{"i": "NCIT:C13555", "l": "3q", "d": ["Distal (long) arm of chromosome 3"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2246703", "l": "eukaryotic 48S preinitiation complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990530", "l": "Cdc50p-Drs2p complex", "d": ["A protein complex that functions as a phospholipid-translocating P-Type ATPase. 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In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2611286", "l": "SRF-myogenin-E12 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754392", "l": "protocadherin-alpha-v7-protocadherin-gamma-b2 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4236760", "l": "endothelial cell-matrix adhesion via fibronectin", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166926", "l": "mRNA cap complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2325685", "l": "Cytosol of neural cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0097591", "l": "ventral disc lateral crest", "d": ["Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). 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It contains a histone-fold/TFIID-TAF/NF-Y domain. Similar sequences have been identified in Schizosaccharomyces pombe. The Drosophila gene Chrac-16 also encodes a component of the chromatin accessibility complex. (from FlyBase 0043002, 0043001, and NCI)"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754871", "l": "catenin-TCF7L2 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1517655", "l": "Karyosome", "d": [], "t": []}, {"i": "NCIT:C32893", "l": "Karyosome", "d": ["A cluster of highly aggregated chromatin."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5450344", "l": "gamma-tubulin large complex, mitotic spindle pole body", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2612830", "l": "Itgax-Itgb2 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325703", "l": "megasporocyte nucleus", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.858242952019168", "identifiers": [{"i": "GO:0097217", "l": "sieve area", "d": ["A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "85.510657888247053", "identifiers": [{"i": "UMLS:C1521538", "l": "6p21.2", "d": [], "t": []}, {"i": "NCIT:C13487", "l": "6p21.2", "d": ["A chromosome band present on 6p"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2752460", "l": "host cell endoplasmic reticulum membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0061202", "l": "clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane", "d": ["The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "84.187358309157389", "identifiers": [{"i": "UMLS:C1520771", "l": "17q21.1", "d": [], "t": []}, {"i": "NCIT:C13504", "l": "17q21.1", "d": ["A chromosome band present on 17q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0106095", "l": "m7G(5')pppN diphosphatase complex", "d": ["A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "79.616479785166973", "identifiers": [{"i": "GO:0034708", "l": "methyltransferase complex", "d": ["A protein complex that possesses methyltransferase activity."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4235128", "l": "chloroplast thylakoid membrane protein complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2246493", "l": "amyloplast inner membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1180038", "l": "Tip of cilium", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "UMLS:C1521468", "l": "5q12-q13", "d": [], "t": []}, {"i": "NCIT:C13874", "l": "5q12-q13", "d": ["A chromosome band present on 5q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821190", "l": "ventral disc lateral crest", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5137258", "l": "tryptase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824301", "l": "maltose transporter inhibitor complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4328789", "l": "dynamic microtubule bundle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3271527", "l": "tectonic-like complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1749471", "l": "nuclear membrane lumen", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.858242952019168", "identifiers": [{"i": "UMLS:C1710961", "l": "2q31", "d": [], "t": []}, {"i": "NCIT:C54239", "l": "2q31", "d": ["A chromosome band present on 2q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3271327", "l": "ribonucleoprotein granule", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167366", "l": "collagen type VII trimer location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166856", "l": "eukaryotic translation initiation factor 4F complex location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3893603", "l": "phosphatidylinositol 3-kinase complex, class I", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044615", "l": "nuclear pore nuclear basket", "d": ["A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). 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In vertebrates, Tpr is a major component."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "82.142077680952909", "identifiers": [{"i": "GO:0043667", "l": "pollen wall", "d": ["The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824264", "l": "molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2262697", "l": "cortical microtubule", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1819023", "l": "Chromosome passenger complex location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "79.042693372152272", "identifiers": [{"i": "GO:0030286", "l": "dynein complex", "d": ["Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0596975", "l": "mossy fiber", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3546341", "l": "coenzyme M methyltransferase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2331109", "l": "Plasma membrane of Type L enteroendocrine cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325664", "l": "chloroplast nucleoid", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0045251", "l": "electron transfer flavoprotein complex", "d": ["A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0019029", "l": "helical viral capsid", "d": ["The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0062074", "l": "pollen aperture", "d": ["An area where exine is reduced or absent, in the pollen wall."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821256", "l": "deuterosome", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0033593", "l": "BRCA2-MAGE-D1 complex", "d": ["A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.858242952019168", "identifiers": [{"i": "UMLS:C1520864", "l": "19q13.31", "d": [], "t": []}, {"i": "NCIT:C28650", "l": "19q13.31", "d": ["A chromosome band present on 19q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1819396", "l": "homodimeric decaprenyl diphosphate synthase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754328", "l": "alphaV-beta6 integrin-osteopontin complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4690291", "l": "K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230667", "l": "Pellicle, as in protozoal parasite", "d": [], "t": []}, {"i": "SNOMEDCT:15140004", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166859", "l": "transport protein particle complex location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2333064", "l": "Set of cytoplasmic organelles of epithelial cell of renal tubule", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3824238", "l": "RQC complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "67.652735569199962", "identifiers": [{"i": "GO:0000781", "l": "chromosome, telomeric region", "d": ["The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. 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The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. 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The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "55.193888465602839", "identifiers": [{"i": "GO:0030016", "l": "myofibril", "d": ["The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "44.748160609831366", "identifiers": [{"i": "GO:0043228", "l": "non-membrane-bounded organelle", "d": ["Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. 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In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2246674", "l": "CORVET complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4327162", "l": "tenascin complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230903", "l": "Basal lamina of epithelial cell or tissue", "d": [], "t": []}, {"i": "SNOMEDCT:32565005", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3268794", "l": "clathrin-sculpted monoamine transport vesicle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0098031", "l": "icosahedral viral capsid, collar", "d": ["A small disk located at the base of some icosahedral virus capsids."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0031039", "l": "macronucleus", "d": ["A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. 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In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. 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In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167097", "l": "Cdc73/Paf1 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "UMLS:C1521406", "l": "4q28.2-q31.1", "d": [], "t": []}, {"i": "NCIT:C38183", "l": "4q28.2-q31.1", "d": ["A chromosome band present on 4q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.386748736829375", "identifiers": [{"i": "UMLS:C2825751", "l": "22q13.31", "d": [], "t": []}, {"i": "NCIT:C81832", "l": "22q13.31", "d": ["A chromosome band present on 22q."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230515", "l": "Infranuclear region of polarized cell", "d": [], "t": []}, {"i": "SNOMEDCT:49757006", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070556", "l": "TAF4B-containing transcription factor TFIID complex", "d": ["A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.386748736829375", "identifiers": [{"i": "GO:1990078", "l": "replication inhibiting complex", "d": ["A protein complex that inhibits multiple events of replication initiation during one replication cycle."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "75.674113164858127", "identifiers": [{"i": "MESH:D002891", "l": "Chromosomes, Human, Pair 21", "d": [], "t": []}, {"i": "UMLS:C0008664", "l": "Chromosomes, Human, Pair 21", "d": [], "t": []}, {"i": "NCIT:C13217", "l": "Human Chromosome 21", "d": ["The designation for each member of the second smallest human autosomal chromosome pair. Chromosome 21 spans around 47 million nucleotides and represents about 1.5% of the total DNA in normal diploid cells."], "t": []}, {"i": "SNOMEDCT:43009003", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "28.025435566862637", "identifiers": [{"i": "GO:0110165", "l": "cellular anatomical entity", "d": ["A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. 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The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "87.167921677548108", "identifiers": [{"i": "MESH:D059547", "l": "Stereocilia", "d": [], "t": []}, {"i": "UMLS:C0230626", "l": "Stereocilia", "d": [], "t": []}, {"i": "NCIT:C33614", "l": "Stereocilium", "d": ["A non-motile microvillus-like structure found in certain epithelial tissues. It is comprised of plasma membrane that is supported by longitudinal actin filaments."], "t": []}, {"i": "SNOMEDCT:36828001", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1748485", "l": "primary cell septum", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1902737", "l": "dendritic filopodium", "d": ["A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "82.597043153557706", "identifiers": [{"i": "GO:0022624", "l": "proteasome accessory complex", "d": ["A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990047", "l": "spindle matrix", "d": ["A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:1990742", "l": "microvesicle", "d": ["An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "UMLS:C1520387", "l": "11q13.3-q14.1", "d": [], "t": []}, {"i": "NCIT:C39290", "l": "11q13.3-q14.1", "d": ["A chromosome band present on 11q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3156853", "l": "periarbuscular membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821138", "l": "axonemal central pair", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031511", "l": "Mis6-Sim4 complex", "d": ["A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821171", "l": "lateral part of cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "UMLS:C1521634", "l": "7p22.2", "d": [], "t": []}, {"i": "NCIT:C38941", "l": "7p22.2", "d": ["A chromosome band present on 7p"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167374", "l": "fibrillar collagen trimer location", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167430", "l": "carbamoyl-phosphate synthase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0038143", "l": "ERBB3:ERBB2 complex", "d": ["A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. 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Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.08573956302773", "identifiers": [{"i": "UMLS:C0796365", "l": "8p22", "d": [], "t": []}, {"i": "NCIT:C13388", "l": "8p22", "d": ["A chromosome band present on 8p"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167002", "l": "proplastid", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325727", "l": "THO complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4235108", "l": "EARP complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754968", "l": "IgD immunoglobulin complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4327136", "l": "interleukin-10 receptor complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325834", "l": "viral glycoprotein", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2246387", "l": "IgG receptor complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034422", "l": "aleurone grain lumen", "d": ["The volume enclosed by the membrane of an aleurone grain."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "UMLS:C1512874", "l": "Internal Lumen of the Centriole", "d": [], "t": []}, {"i": "NCIT:C32851", "l": "Internal Lumen of the Centriole", "d": ["The space bounded by the nine microtubule triplets of the centriole."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "GO:0009654", "l": "photosystem II oxygen evolving complex", "d": ["A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230603", "l": "Cell membrane, lateral aspect of polarized cell", "d": [], "t": []}, {"i": "SNOMEDCT:56865006", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "68.213213433239261", "identifiers": [{"i": "GO:0045111", "l": "intermediate filament cytoskeleton", "d": ["Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. 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Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4326883", "l": "ADDL complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120513", "l": "2-(3-amino-3-carboxypropyl)histidine synthase complex", "d": ["A protein complex capable of catalysing the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the histidine residue of translation elongation factor 2 (EF2), which is the first step in the biosynthesis of diphthamide. The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2754982", "l": "membrane-bound IgA2", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.755328944123519", "identifiers": [{"i": "GO:0098981", "l": "cholinergic synapse", "d": ["A synapse that uses acetylcholine as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "NCIT:C164528", "l": "Genetic Location", "d": ["The location of the genetic or genomic sequence that is described by the test result."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0230928", "l": "Flagellum, bacterial", "d": [], "t": []}, {"i": "SNOMEDCT:41792001", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "MESH:D021961", "l": "Cell Membrane Structures", "d": [], "t": []}, {"i": "UMLS:C0887867", "l": "Cell Membrane Structures", "d": [], "t": []}, {"i": "SNOMEDCT:312241000", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.386748736829375", "identifiers": [{"i": "UMLS:C1520257", "l": "10p11.21", "d": [], "t": []}, {"i": "NCIT:C26075", "l": "10p11.21", "d": ["A chromosome band present on 10p"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097504", "l": "Gemini of coiled bodies", "d": ["Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). 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In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070088", "l": "polyhydroxyalkanoate granule", "d": ["An inclusion body located in the cytoplasm of prokaryotes that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990794", "l": "basolateral part of cell", "d": ["The region of a cell situated by the cell sides which interface adjacent cells and near the base. 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In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. 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Can be heterotrimeric or heterodimeric."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3821183", "l": "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1325539", "l": "Casparian strip", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3896478", "l": "Golgi cis cisterna membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.858242952019168", "identifiers": [{"i": "NCIT:C13544", "l": "18p", "d": ["Proximal (short) arm of chromosome 18"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "UMLS:C1520707", "l": "16q24.2-q24.3", "d": [], "t": []}, {"i": "NCIT:C13852", "l": "16q24.2-q24.3", "d": ["A chromosome band present on 16q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031080", "l": "nuclear pore outer ring", "d": ["A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates)."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1622086", "l": "filopodium membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3158687", "l": "PR-DUB complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2330545", "l": "Surface of smooth muscle cell", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5379848", "l": "ELL-EAF-EBP complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1817825", "l": "myosin complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166695", "l": "Prophase chromosome", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.429121476009584", "identifiers": [{"i": "UMLS:C1520623", "l": "15q11.2-q21.3", "d": [], "t": []}, {"i": "NCIT:C38590", "l": "15q11.2-q21.3", "d": ["A chromosome band present on 15q"], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167314", "l": "virion transport vesicle", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1166946", "l": "phragmoplast", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3823076", "l": "glucosidase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "71.707063856546881", "identifiers": [{"i": "GO:1905369", "l": "endopeptidase complex", "d": ["A protein complex which is capable of endopeptidase activity."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0042653", "l": "mitochondrial respiratory chain complex I, membrane segment", "d": ["The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "MESH:D057907", "l": "Post-Synaptic Density", "d": [], "t": []}, {"i": "UMLS:C1817671", "l": "Post-Synaptic Density", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3155704", "l": "type II terminal bouton", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4690690", "l": "SUMO ligase complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2323215", "l": "Set of cytoplasmic organelles of adipocyte", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3158696", "l": "NF-kappa p105/p65 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C2752532", "l": "other organism membrane", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3822732", "l": "endoribonuclease complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.386748736829375", "identifiers": [{"i": "GO:0005697", "l": "telomerase holoenzyme complex", "d": ["Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3548553", "l": "Flemming body", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0333745", "l": "Councilman body", "d": [], "t": []}, {"i": "SNOMEDCT:18958005", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C4512550", "l": "Entire intercellular canaliculus", "d": [], "t": []}, {"i": "SNOMEDCT:727315007", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "64.402443444347739", "identifiers": [{"i": "MESH:D002880", "l": "Chromosomes, Human, Pair 11", "d": [], "t": []}, {"i": "UMLS:C0008653", "l": "Chromosomes, Human, Pair 11", "d": [], "t": []}, {"i": "NCIT:C13206", "l": "Human Chromosome 11", "d": ["The designation for each member of the eleventh largest human autosomal chromosome pair. Chromosome 11 spans about 134.5 million base pairs and represents between 4 and 4.5% of the total DNA in normal diploid cells."], "t": []}, {"i": "SNOMEDCT:16312006", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990097", "l": "SeqA-DNA complex", "d": ["A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1167094", "l": "RNA polymerase II, holoenzyme", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C5380039", "l": "cytoplasmic microtubule minus-end", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005916", "l": "fascia adherens", "d": ["A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C0333831", "l": "Reilly body", "d": [], "t": []}, {"i": "SNOMEDCT:87369008", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3271859", "l": "ERBB4:ERBB2 heterodimer", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.08573956302773", "identifiers": [{"i": "GO:0044228", "l": "host cell surface", "d": ["The external part of the host cell wall and/or host plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "MESH:D000086942", "l": "Viral Envelope", "d": [], "t": []}, {"i": "UMLS:C1167398", "l": "Viral Envelope", "d": [], "t": []}, {"i": "SNOMEDCT:115427003", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C1749467", "l": "soluble", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "identifiers": [{"i": "UMLS:C3896313", "l": "Dom34-Hbs1 complex", "d": [], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1325725", "l": "Virus-like particle", "d": [], "t": []}, {"i": "NCIT:C14324", "l": "Virus-like Particle", "d": ["Non-infectious particle(s) derived from viral structural proteins. These particles are used as vaccines to stimulate a host immune response against the virus that the particles were derived from."], "t": []}], "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0042721", "l": "TIM22 mitochondrial import inner membrane insertion complex", "d": ["A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12."], "t": []}], "taxa": []}