name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Drosophila melanogaster)


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Dictyostelium discoideum)


name: (2S)-sakuranetin + O2 + reduced [NADPH--hemoprotein reductase] => (2S)-7-methylcarthamidin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a guanosine in RNA + glyoxal = an N(2)-(1-hydroxy-2-oxoethyl)-guanosine in RNA


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + ATP + H2O <=> 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + ADP + H(+) + phosphate


name: dihydrophloroglucinol + NADP(+) <=> 1,3,5-trihydroxybenzene + NADPH


name: H2O + L-alanyl-L-histidine => L-alanine + L-histidine


name: 4-hydroxybenzoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => benzoate + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-deoxy-D-glucose 6-phosphate + NAD(+) => 2-deoxy-6-phospho-D-glucono-1,5-lactone + H(+) + NADH


name: a 3'-end 2'-phospho-ribonucleotide-RNA + H(+) => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O


name: USP33 deubiquitinates ROBO1 (Bos taurus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in) => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: diphosphate + ent-isokaurene => ent-copalyl diphosphate


name: all-trans-4,4'-diaponeurosporene + FAD + H(+) <=> all-trans-4,4'-diapolycopene + FADH2


name: SLC7A8-mediated uptake of neutral amino acids (Bos taurus)


name: 5-deoxy-D-ribulose 1-phosphate = acetaldehyde + dihydroxyacetone phosphate


name: p-S215 FOXO3 translocates to the nucleus (Sus scrofa)


name: UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Dictyostelium discoideum)


name: TGFBR3_mem cleavage by MMPs (Canis familiaris)


name: STAT4 binds p-Y-IL23R in IL23:IL23 receptor (Sus scrofa)


name: Abortive initiation after formation of the first phosphodiester bond (Mus musculus)


name: Caspase-mediated cleavage of E-Cadherin (Bos taurus)


name: 3-(aminomethyl)indole + S-adenosyl-L-methionine <=> (1H-indol-3-yl)-N-methylmethanamine + H(+) + S-adenosyl-L-homocysteine


name: 7,8-dihydroneopterin 3'-triphosphate => 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Homo sapiens)


name: (-)-secoisolariciresinol + NADP(+) => (+)-lariciresinol + H(+) + NADPH


name: a 2-deoxy-alpha-D-glucoside + H2O = 2-deoxy-D-glucose + an alcohol


name: PARK2 K63-Ubiquitinates SNCAIP (Homo sapiens)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Danio rerio)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine => 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: FMNH2 + N-methylnicotinate + O2 => (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+)


name: 4-hydroxybutanoate + NADP(+) = H(+) + NADPH + succinate semialdehyde


name: ADP + H(+) + O-phospho-L-threonyl-[receptor-protein] => ATP + L-threonyl-[receptor-protein]


name: (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = pyruvate + salicylaldehyde


name: L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] <=> H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu)


name: 2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) <=> 4-CDP-2-C-methyl-D-erythritol + diphosphate


name: UCKL1 phosphorylates urindine, cytidine (Canis familiaris)


name: glutamate uptake by astrocytes (Drosophila melanogaster)


name: Fibronectin degradation by CTSG (Sus scrofa)


name: T2Rs bind bitter-tasting compounds (Homo sapiens)


name: salicylate + UDP-alpha-D-glucose = H(+) + salicylate 2-O-beta-D-glucoside + UDP


name: 3,4-dinitrotoluene + NADH + O2 => 4-methyl-6-nitrocatechol + NAD(+) + nitrite


name: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH


name: "diacetyl reductase [(R)-acetoin forming]"


name: Na+/H+ exchanger transport (at cell membrane) (Xenopus tropicalis)


name: TFIIS-mediated recovery of elongation from arrest (Homo sapiens)


name: HRH3 binds pitosilant (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ATP + CoA <=> (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + AMP + diphosphate


name: 4-acetamidobutanoate + H2O = 4-aminobutanoate + acetate


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Caenorhabditis elegans)


name: HCCS inserts heme into cytochrome c (Mus musculus)


name: 2',3'-cyclophospho-GMP + H2O = 3'-GMP + H(+)


name: IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Homo sapiens)


name: Phosphorylation of Cyclin A:Cdk2 at Tyr 15 (Homo sapiens)


name: Extracellular BTD hydrolyses BCTN (Danio rerio)


name: F inhibitors bind F on RSV virion (Homo sapiens)


name: HDAC6 deacetylates microtubules (Mus musculus)


name: NADPH transfers electrons to FDXR (Rattus norvegicus)


name: alpha-isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-D-maltotriose = cyclobis-(1->3)-alpha-D-isomaltosyl + D-maltotriose


name: Proglucagon translocates from the ER Lumen to secretory granules (Sus scrofa)


name: Autophosphorylation of PAK1,2,3 (Canis familiaris)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Sus scrofa)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Sus scrofa)


name: p-4Y-SIRPA:CD47:SKAP2 binds FYB (Homo sapiens)


name: (20S)-hydroxypregn-4-en-3-one + NAD(+) => H(+) + NADH + progesterone


name: IL4:IL4R:JAK2 binds IL2RG:JAK3 (Homo sapiens)


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + choline + H(+)


name: p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus (Canis familiaris)


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)


name: H2O + queuosine 5'-phosphate => D-ribose 5-phosphate + queuine


name: BTK in G alpha (12)-BTK complex is activated (Rattus norvegicus)


name: BIL binds GSTA1, FABP1 (Canis familiaris)


name: Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants (Homo sapiens)


name: ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC (Mus musculus)


name: phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP (Bos taurus)


name: adenosine(out) + 2 Na(+)(out) => adenosine(in) + 2 Na(+)(in)


name: NADP(+) + xylitol => H(+) + L-xylulose + NADPH


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Saccharomyces cerevisiae)


name: a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+) => a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose


name: ABHD10 hydrolyses MPAG (Xenopus tropicalis)


name: S-adenosyl-L-homocysteine + S-methyl-L-methionyl-[protein] => L-methionyl-[protein] + S-adenosyl-L-methionine


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Rattus norvegicus)


name: eicosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 2-hydroxyeicosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: 3,4,5-trihydroxybenzoate(in) + H(+)(in) => 3,4,5-trihydroxybenzoate(out) + H(+)(out)


name: diphosphate + macrophomene => all-trans-hexaprenyl diphosphate


name: RHOD:GTP recruits DAIPH2-3 to endosomes (Mus musculus)


name: 2 5,6-dihydroxyindole-2-carboxylate + O2 => 2 H2O + 2 indole-5,6-quinone-2-carboxylate


name: Formation of the SET1B complex (Saccharomyces cerevisiae)


name: H2O + L-threonyl-tRNA(Ser) => L-threonine + tRNA(Ser)


name: ATP + H2O + spermine(out) => ADP + H(+) + phosphate + spermine(in)


name: Duplex miRNA is loaded into Argonaute (Drosophila melanogaster)


name: CHRM2,4 bind acetylcholine (Xenopus tropicalis)


name: RHAG transports CO2 from cytosol to extracellular region (Gallus gallus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(in) + ATP + H2O <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(out) + ADP + H(+) + phosphate


name: S-adenosyl-L-methionine + uridine(1939) in 23S rRNA => 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: MIB2 ubiquitinates CYLD at K338, K530 (Drosophila melanogaster)


name: ACBD4,5 bind MCFA-CoA and LCFA-CoA (Homo sapiens)


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Canis familiaris)


name: methotrexate transmembrane transporter activity


name: 13-(9Z-hexadecenoyloxy)-octadecanoate + H2O => (9Z)-hexadecenoate + 13-hydroxy-octadecanoate + H(+)


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Xenopus tropicalis)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)


name: G-protein beta-gamma subunits rebind the alpha-GDP subunit (Sus scrofa)


name: ATP + H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out) <=> ADP + H(+) + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) + phosphate


name: Aquaporins passively transport urea out of cells (Rattus norvegicus)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Sus scrofa)


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Plasmodium falciparum)


name: ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Homo sapiens)


name: ATP binding to HSP90 triggers conformation change (Schizosaccharomyces pombe)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Sus scrofa)


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: (R)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH => (1S,2R)-ephedrine + NAD(+)


name: Activation of Potassium transport channels (Rattus norvegicus)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Sus scrofa)


name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 (Homo sapiens)


name: L-ornithine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) <=> L-ornithine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: SRC-1 phosphorylates SHB (Canis familiaris)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Sus scrofa)


name: citrate(out) + trans-aconitate(in) = citrate(in) + trans-aconitate(out)


name: Transport of Antigen peptide in to ER (Homo sapiens)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O <=> (9Z)-octadecenoate + 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: acetate + H(+) + holo-[citrate lyase ACP] => acetyl-[citrate lyase ACP] + H2O


name: PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Homo sapiens)


name: ATP + N(6)-(D-psicosyl)-L-lysyl-[protein] <=> ADP + H(+) + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein]


name: Activated FGFR1 phosphorylates SHC1 (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + taxusin => 2alpha-hydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Xenopus tropicalis)


name: PRKAA2 phosphorylates nuclear NFE2L2 (Mus musculus)


name: coenzyme M + methyl-Co(III)-[methylated-thiol-specific corrinoid protein] <=> Co(I)-[methylated-thiol-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: CUL9:RBX1 ubiquitinates BIRC5 (Homo sapiens)


name: a 2-acyl-4-prenylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4,6-diprenylphloroglucinol + diphosphate


name: D-xylose + NADP(+) <=> D-xylono-1,5-lactone + H(+) + NADPH


name: WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it (Homo sapiens)


name: H2O + protodioscin = 26-deglucoprotodioscin + D-glucose


name: geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphate


name: ATP + estrone 3-sulfate(out) + H2O => ADP + estrone 3-sulfate(in) + H(+) + phosphate


name: 5-dehydro-D-gluconate + NADP(+) => 2,5-didehydro-D-gluconate + H(+) + NADPH


name: biphenyl + H(+) + NADH + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)


name: D-sedoheptulose 7-phosphate = 2-epi-5-epi-valiolone + phosphate


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Sus scrofa)


name: ESTG binds ESR2:chaperone complex (Bos taurus)


name: SQSTM1 oligomer is phosphorylated (Homo sapiens)


name: (2R)-hydroxyhexadecanoyl-CoA <=> formyl-CoA + pentadecanal


name: p-6Y-SYK phosphorylates VAV1,2,3 (Homo sapiens)


name: AFG3L2 binds mitochondrial inner membrane proteins (Mus musculus)


name: CYP46A1 24-hydroxylates CHOL (Xenopus tropicalis)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Drosophila melanogaster)


name: a 2-oxo-3-(phosphooxy)propyl medium-chain 3-oxoalkanoate + holo-[ACP] => a medium-chain 3-oxoacyl-[ACP] + dihydroxyacetone phosphate


name: ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate <=> ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate


name: adenosine in double-stranded RNA + H(+) + H2O = inosine in double-stranded RNA + NH4(+)


name: 20cooh-LTB4 is converted to 18cooh-LTB4 (Homo sapiens)


name: ADPRM hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Drosophila melanogaster)


name: vascular endothelial growth factor receptor 3 binding


name: thiosulfate transmembrane transporter activity


name: AMP + diphosphate + diphthamide-[translation elongation factor 2] + H(+) => ATP + diphthine-[translation elongation factor 2] + NH4(+)


name: G alpha (q) binds to Trio family RhoGEFs (Canis familiaris)


name: ALOX5 oxidises EPA to 5-HEPE (Mus musculus)


name: (2R)-3-phospho-glyceroyl phosphate + 2-deoxy-alpha-D-ribose 1-phosphate => (2R)-3-phosphoglycerate + 2-deoxy-alpha-D-ribose 1,5-bisphosphate + H(+)


name: ATP + H2O + methionine(out) <=> ADP + H(+) + methionine(in) + phosphate


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Mus musculus)


name: Release of STAT1 dimer from active receptor unit (Sus scrofa)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: CoA + H(+) + N-docosanoyl-3-ketodihydrosphingosine => 3-oxosphinganine + docosanoyl-CoA


name: ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] <=> ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase]


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Canis familiaris)


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Mus musculus)


name: Retromer recycles WLS to the Golgi (Mus musculus)


name: (9Z)-octadecenoate + L-serine => H2O + N-(9Z-octadecenoyl)-L-serine


name: 2-methylcyclohexanone + H(+) + NADPH + NH4(+) => (1S)-2-methyl-cyclohexylamine + H2O + NADP(+)


name: PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Canis familiaris)


name: PLB1 hydrolyses RPALM to atROL (Canis familiaris)


name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Homo sapiens)


name: Association of DFF with alpha:beta importin (Bos taurus)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-methionine


name: L-glutamate + L-glutamate 5-semialdehyde => 2-oxoglutarate + L-ornithine


name: alpha-carotene epsilon hydroxylase activity


name: LTA trimer binds TNFRSF1A,1B,14 (Danio rerio)


name: ADP + cyclic (2R)-2,3-bisphosphoglycerate + phosphate => (2R)-2,3-bisphosphoglycerate + ATP + H(+)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Homo sapiens)


name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 (Homo sapiens)


name: CYP51A1 demethylates LNSOL (Canis familiaris)


name: (R)-6-hydroxynicotine + AH2 => (R)-nicotine + A + H2O


name: LDLR:LDL complex => LDLR + LDL (Homo sapiens)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Rattus norvegicus)


name: CO + H(+) + N-formylanthranilate => 3-hydroxy-1H-quinolin-4-one + O2


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Xenopus tropicalis)


name: D-ribitol 5-phosphate + NAD(+) = D-ribulose 5-phosphate + H(+) + NADH


name: H2A-H2B histone complex chaperone activity


name: MPG glycosylase mediated recognition and binding of hypoxanthine (Homo sapiens)


name: a tRNA with a 3' CCA end + ATP + 2 CTP <=> a tRNA with a 3' CCACCA end + 3 diphosphate


name: 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Homo sapiens)


name: HIPK2 phosphorylates MECP2 (Mus musculus)


name: IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Sus scrofa)


name: 2-oxo-dADP + H2O => 2-oxo-dAMP + H(+) + phosphate


name: 1-eicosanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + eicosanoyl-CoA


name: CYCS:APAF1 binds procaspase-9 (Canis familiaris)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Danio rerio)


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Sus scrofa)


name: GNRHR binds chemical antagonists (Xenopus tropicalis)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Danio rerio)


name: Part of the ICD migrates to the nucleus (Xenopus tropicalis)


name: N-acetyl-alpha-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N,N'-diacetylchitobiosyl diphosphodolichol + UDP


name: ATP + dodecanoate(out) + H2O = ADP + dodecanoate(in) + H(+) + phosphate


name: L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Saccharomyces cerevisiae)


name: PKC phosphorylates sphingosine kinase 1 (Rattus norvegicus)


name: (E)-hept-2-enal + H2O + NADP(+) <=> (E)-hept-2-enoate + 2 H(+) + NADPH


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 O2 => 2 CO2 + 2 formaldehyde + L-lysyl(9)-[histone H3] + 2 succinate


name: TBC1D7 binds the TSC1-TSC2 complex (Bos taurus)


name: Condensin II complex binds H4K20me1-containing nucleosomes (Gallus gallus)


name: 7-chloroindole-3-pyruvate imine dimer + 2 H2O => 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2


name: D-loop extension by DNA polymerases (Bos taurus)


name: 9alpha-copalyl diphosphate <=> diphosphate + isopimara-8(14),15-diene


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Rattus norvegicus)


name: O2 + octanedioyl-CoA = (2E)-octenedioyl-CoA + H2O2


name: MPI isomerises Fru6P to Man6P (Gallus gallus)


name: acetochlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => ethyl formate + H2O + N-(2-ethyl-6-methylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H2O + O2 + salicylaldehyde = H(+) + H2O2 + salicylate


name: glyoxylate + NH4(+) + urea => (S)-2-ureidoglycine + H2O


name: glycyl-L-histidine + H2O = glycine + L-histidine


name: 5-(9Z-octadecenoyloxy)-octadecanoate + H2O => (9Z)-octadecenoate + 5-hydroxy-octadecanoate + H(+)


name: CoA + NADP(+) + succinate semialdehyde => H(+) + NADPH + succinyl-CoA


name: (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + CO2 + CoA


name: RAC1 GDIs block activation of RAC1 (Rattus norvegicus)


name: L-methionine + S-adenosyl-L-methionine => S-adenosyl-L-homocysteine + S-methyl-L-methionine


name: Role of myosins in phagosome formation (Mus musculus)


name: L-lysyl(9)-[histone H3] + 2 S-adenosyl-L-methionine => 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 S-adenosyl-L-homocysteine


name: (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O => (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol


name: LUM (lumican) binds integrin alpha2beta1 (Homo sapiens)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Rattus norvegicus)


name: NT5C2 tetramer dephosphorylates RBV-MP (Sus scrofa)


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Sus scrofa)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Bos taurus)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: holo-[(phenol)carboxyphthiodiolenone synthase] + icosanoyl-AMP <=> AMP + H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: IFNG dimer binds IFNGR (Rattus norvegicus)


name: USP45 deubiquitinates ERCC1 (Sus scrofa)


name: (S)-3'-hydroxy-N-methylcoclaurine + S-adenosyl-L-methionine = (S)-reticuline + H(+) + S-adenosyl-L-homocysteine


name: 15-cis-4,4'-diapophytoene + 2 diphosphate => 2 (2E,6E)-farnesyl diphosphate


name: Trimerization of TRAIL:TRAIL receptor complex (Rattus norvegicus)


name: (13E)-labda-7,13-dien-15-yl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphate


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Drosophila melanogaster)


name: 3-oxosphinganine + hexadecanoyl-CoA = CoA + H(+) + N-hexadecanoyl-3-oxosphinganine


name: Autophosphorylation of PDGF alpha/beta receptors (Danio rerio)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Bos taurus)


name: 17beta-hydroxy-5alpha-androstan-3-one + UDP-alpha-D-glucuronate <=> 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + H(+) + UDP


name: receptor serine/threonine kinase binding


name: basic amino acid transmembrane transporter activity


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Danio rerio)


name: oxalate + succinyl-CoA => oxalyl-CoA + succinate


name: SLC45A3 transports Glc from extracellular region to cytosol (Xenopus tropicalis)


name: TDO tetramer dioxygenates L-Trp to NFK (Rattus norvegicus)


name: 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA => 3-methylundecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: Activation of Cdc25C (Rattus norvegicus)


name: 5-O-[(E)-caffeoyl]-shikimate + H2O = (E)-caffeate + H(+) + shikimate


name: (10S)-hydroxy-(12Z)-octadecenoate => (9Z,12Z)-octadecadienoate + H2O


name: SALMs1-3 bind each other in cis interactions (Bos taurus)


name: 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NAD(+) <=> 3-dehydro-4alpha-methylzymosterol + CO2 + NADH


name: Recruitment of CBL to KIT (Homo sapiens)


name: catechol + H(+) + NADPH => (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+)


name: Na(+)(in) + O-acetyl-(R)-carnitine(in) => Na(+)(out) + O-acetyl-(R)-carnitine(out)


name: Active LTK recruits GRB2:SOS1 (Mus musculus)


name: Release of platelet secretory granule components (Danio rerio)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Drosophila melanogaster)


name: gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity


name: adenosine 3',5'-bisphosphate + H(+) + omega-sulfo-beta-dihydromenaquinone-9 => 3'-phosphoadenylyl sulfate + omega-hydroxy-beta-dihydromenaquinone-9


name: Translocation of TRAF6 to CBM complex (Homo sapiens)


name: dihydrocarvone + H(+) + NADPH + O2 => 4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Sus scrofa)


name: MAPKs phosphorylate PP2A (Canis familiaris)


name: holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Mus musculus)


name: a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Conversion of C4 into C4a and C4b (Canis familiaris)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (R)-axinyssene + diphosphate


name: GALNT3 transfers GalNAc to FGF23 (Mus musculus)


name: Active ALK phosphorylates JAK3 (Homo sapiens)


name: 1-nonadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: 2-oxobutanoate + glycine => (2S)-2-aminobutanoate + glyoxylate


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Canis familiaris)


name: H2O + N-docosanoylglycine => docosanoate + glycine


name: a 7-hydroxyisoflavone + UDP-alpha-D-glucose => a 7-hydroxyisoflavone 7-O-beta-D-glucoside + H(+) + UDP


name: 15,16-dihydrobiliverdin + oxidized 2[4Fe-4S]-[ferredoxin] = biliverdin IXalpha + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(28-hydroxyoctacosanoyl)-sphing-4-enine = a diacylglycerol + N-(28-(9Z,12Z-octadecadienoyloxy)-octacosanoyl)-sphing-4-enine


name: NH4(+) + oxaloacetate => 2-oxosuccinamate + H2O


name: 2-oxoglutarate + O2 + octadecanoyl-CoA => 2-hydroxyoctadecanoyl-CoA + CO2 + succinate


name: SUMOylation of Histone H4 with SUMO3 (Drosophila melanogaster)


name: Activated P2Y purinoceptor 12 binds G-protein Gi (Xenopus tropicalis)


name: dehydro coenzyme F420-0 + FMNH2 => FMN + H(+) + oxidized coenzyme F420-0


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Bos taurus)


name: zinc ion transmembrane transporter activity


name: "Catalysing the translocation of hydrons"


name: TLE tetramers bind TCF/LEF at WNT promoters (Caenorhabditis elegans)


name: a 5'-end ribonucleotide-tRNA(His) + ATP + GTP + H2O <=> a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)


name: NICD1 in complex with RBPJ (CSL) recruits MAML (Mus musculus)


name: 11-hydroxycucurbitadienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cucurbitadienol + O2 + reduced [NADPH--hemoprotein reductase]


name: (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 <=> (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate


name: oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor


name: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome (Homo sapiens)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Rattus norvegicus)


name: cholesterol + NAD(+) <=> cholest-5-en-3-one + H(+) + NADH


name: CAMK2 binds MAP3K7 (Drosophila melanogaster)


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine


name: Phosphorylation of COP1 at Ser-387  by ATM (Sus scrofa)


name: PRC2 trimethylates histone H3 at lysine-27 (Canis familiaris)


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Gallus gallus)


name: TXNIP binds reduced thioredoxin (Bos taurus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + octanoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-octanoyl-sn-glycerol + CoA


name: 2 L-leucyl-tRNA(Leu) => cyclo(L-leucyl-L-leucyl) + 2 H(+) + 2 tRNA(Leu)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Xenopus tropicalis)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)


name: Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs (Homo sapiens)


name: Phosphorylation of Syntaxin-4 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base => a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: (S)-ureidoglycolate + NAD(+) = H(+) + N-carbamoyl-2-oxoglycine + NADH


name: PP2A demethylation by PPME1 (Bos taurus)


name: uridine(38/39) in tRNA <=> pseudouridine(38/39) in tRNA


name: isoorientin + S-adenosyl-L-methionine = H(+) + isoscoparin + S-adenosyl-L-homocysteine


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O <=> 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA + H(+)


name: Transcription of DDIT3 (CHOP, GADD153) in response to heme deficiency (Homo sapiens)


name: prostaglandin G2 => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2


name: dibenzothiophene 5,5-dioxide + FMN-N(5)-peroxide = 2'-hydroxybiphenyl-2-sulfinate + FMN-N(5)-oxide + 2 H(+)


name: CSNK2-mediated phosphorylation of DVL (Bos taurus)


name: 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (5Z,8Z,11Z,14Z)-eicosatetraenedioate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid (Gallus gallus)


name: 3-hydroxyoctanoyl-CoA => (2E)-octenoyl-CoA + H2O


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 => (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Canis familiaris)


name: GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Rattus norvegicus)


name: beta-nicotinamide D-ribonucleotide + H2O = D-ribose 5-phosphate + H(+) + nicotinamide


name: PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA (Rattus norvegicus)


name: D-glucarate transmembrane transporter activity


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Dictyostelium discoideum)


name: 2 Na(+)(in) + pyruvate(in) => 2 Na(+)(out) + pyruvate(out)


name: CO2 + L-xylulose => 3-dehydro-L-gulonate + H(+)


name: Activated protein C cleaves factor Va to factor Vi intermediate form (Mus musculus)


name: TGFBR1 is recruited to tight junctions by PARD6A (Homo sapiens)


name: Dissociation of cytosolic HSF1:HSP90 complex (Rattus norvegicus)


name: 2-glutathionyl-2-methylbut-3-en-1-ol + H2O + 2 NAD(+) = 2-glutathionyl-2-methylbut-3-enoate + 3 H(+) + 2 NADH


name: FMNH2 + N-acetyl-S-benzyl-L-cysteine + O2 => (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: NTRK3 phosphorylates SHC1 (Homo sapiens)


name: (3S)-hydroxy-(9Z-octadecenoyl)-CoA + NAD(+) <=> 3-oxo-(9Z-octadecenoyl)-CoA + H(+) + NADH


name: MECP2 binds CRH gene promoter (Homo sapiens)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Danio rerio)


name: [DsrC protein]-trisulfide + 2 a quinol + H(+) => [DsrC protein]-dithiol + 2 a quinone + 2 H(+) + hydrogen sulfide


name: a (Z)-N-(sulfonatooxy)alkenimidothioate => an alkenyl isothiocyanate + sulfate


name: Histidine is decarboxylated to histamine (Homo sapiens)


name: HLCS biotinylates 6x(PCCA:PCCB) (Sus scrofa)


name: a flavonol 7-O-beta-D-glucoside + malonyl-CoA = a flavonol 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: an N-acylsphing-4-enine + CoA + H(+) => a fatty acyl-CoA + sphing-4-enine


name: a triacyl-sn-glycerol + glycerol => a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycerol


name: UDP-alpha-D-glucuronate(in) + UDP-N-acetyl-alpha-D-glucosamine(out) => UDP-alpha-D-glucuronate(out) + UDP-N-acetyl-alpha-D-glucosamine(in)


name: (2R,3R)-dihydroquercetin + H(+) + NADPH + O2 <=> (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+)


name: D-cellotetraono-1,5-lactone + H2O = D-cellotetraonate + H(+)


name: (R)-lanthionine ketimine + 2 H(+) + NADPH = (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+)


name: sitosterol + UDP-alpha-D-glucose <=> H(+) + sitosteryl 3-beta-D-glucoside + UDP


name: Formation of Cyclin B:Cdc2 complexes (Sus scrofa)


name: NADP(+) + octadecan-1-ol = H(+) + NADPH + octadecanal


name: CO2 + propanoyl-CoA => (R)-methylmalonyl-CoA + H(+)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate


name: a ganglioside GD1alpha + CMP + H(+) => a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Bos taurus)


name: 2 H(+) + O2 + pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-ol


name: (3R)-hydroxyhexadecanoyl-[ACP] <=> (2E)-hexadecenoyl-[ACP] + H2O


name: guanosine(34) in tRNA(Tyr) + queuine = guanine + queuosine(34) in tRNA(Tyr)


name: MPI isomerises Fru6P to Man6P (Bos taurus)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol <=> an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Mus musculus)


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Sus scrofa)


name: H(+) + NADP(+) + 2 reduced [adrenodoxin] <=> NADPH + 2 oxidized [adrenodoxin]


name: an acylcholine + H2O = a carboxylate + choline + H(+)


name: phenylboronic acid monooxygenase activity


name: SUCLG1/A2 cleaves succinyl-CoA (Drosophila melanogaster)


name: Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Homo sapiens)


name: USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Schizosaccharomyces pombe)


name: glycine betaine + L-homocysteine = L-methionine + N,N-dimethylglycine


name: CSN polymer binds CaPO4 (Canis familiaris)


name: 3,5,7-trioxododecanoyl-CoA <=> CO2 + CoA + olivetol


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Homo sapiens)


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexanoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: cordypyrone B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cordypyrone A + O2 + reduced [NADPH--hemoprotein reductase]


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Caenorhabditis elegans)


name: a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1c (d18:1(4E)) + CMP + H(+)


name: LDH tetramer reduces PYR to LACT (Canis familiaris)


name: 2,3-dihydrobiochanin A + NADP(+) <=> biochanin A + 2 H(+) + NADPH


name: SLC19A2/3 transport extracellular THMN to cytosol (Caenorhabditis elegans)


name: H2O + pyrazinamide => NH4(+) + pyrazine-2-carboxylate


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Sus scrofa)


name: sulfate(in) + thiosulfate(out) => sulfate(out) + thiosulfate(in)


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-GMP = GMP + H(+) + lactate


name: STING binds c-di-GMP (Rattus norvegicus)


name: AMP + diphosphate + H(+) + L-seryl-tRNA(Ser) => ATP + L-serine + tRNA(Ser)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Dictyostelium discoideum)


name: mTORC1 phosphorylates AKT1S1 (Sus scrofa)


name: H2O + sucrose 6(F)-phosphate => phosphate + sucrose


name: 2-demethylmenaquinol-12 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-dodecaprenyl diphosphate + H(+)


name: 1,2-dioctadecanoyl-sn-glycerol + phosphate => 1,2-dioctadecanoyl-sn-glycero-3-phosphate + H2O


name: Joining of adjacent Okazaki fragments of the C-strand (Canis familiaris)


name: (S)-tetrahydrocolumbamine + O2 + reduced [NADPH--hemoprotein reductase] => (S)-canadine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + a ribonucleoside 5'-triphosphate => a 5'-end NTP-ribonucleotide-RNA + AMP + H(+)


name: NEIL1 recognizes and binds DHU-dsDNA (Homo sapiens)


name: Inactivation of MAP2K1 by CDK1 (Gallus gallus)


name: L-glucitol + NAD(+) = H(+) + keto-L-fructose + NADH


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Xenopus tropicalis)


name: H(+) + soyasaponin III + UDP => soyasapogenol B 3-O-beta-D-glucuronate + UDP-alpha-D-galactose


name: NADSYN1 hexamer amidates NAAD to NAD+ (Plasmodium falciparum)


name: p52:RELB translocates from cytosol to nucleus (Homo sapiens)


name: tRNA pseudouridine(32) synthase activity


name: Activation of MT-MMPs by FURIN (Rattus norvegicus)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Sus scrofa)


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Rattus norvegicus)


name: H2O + neopikromycin + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: (3R)-hydroxybutanoate pentamer + [(3R)-hydroxybutanoate](n-5) + H(+) => [(3R)-hydroxybutanoate](n) + H2O


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Gallus gallus)


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Mus musculus)


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Homo sapiens)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)


name: glycine(in) + H(+)(out) + Na(+)(in) => glycine(out) + H(+)(in) + Na(+)(out)


name: Substrate translocates into late endosomal lumen (Homo sapiens)


name: an alcohol + H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => a hydroperoxide + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein]


name: a medium-chain (2E)-enoyl-CoA + H2O => a medium-chain (3R)-hydroxyacyl-CoA


name: Autocatalytic activation of bound proMMP2 (Caenorhabditis elegans)


name: Phosphorylation of GAB2 by SFKs (Sus scrofa)


name: BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV (Xenopus tropicalis)


name: Phosphorylation of PLCgamma by PDGFR (Mus musculus)


name: [protein]-disulfide + H(+) + NADH => [protein]-dithiol + NAD(+)


name: H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-L-phenylalanine = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + L-phenylalanine


name: 4-guanidinobutanal + H2O + NAD(+) <=> 4-guanidinobutanoate + 2 H(+) + NADH


name: CXXC1 and WDR82 bind SET1A complex (Canis familiaris)


name: O2 + reduced [NADPH--hemoprotein reductase] + ursodeoxycholate <=> beta-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetate + H(+) + hydroquinone => 4-acetoxyphenol + H2O


name: Interleukin-1 receptor type 1: Interleukin 1 binds Interleukin-1 receptor accessory protein, membrane associated isoform (Homo sapiens)


name: APRT catalyzes the conversion of adenine to AMP (Xenopus tropicalis)


name: S-methyl-5-thio-D-ribulose 1-phosphate => S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: dihydro-ML-236C carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N-acetylserotonin => acetate + serotonin


name: ATP + CoA + propanoate => AMP + diphosphate + propanoyl-CoA


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O => a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+) + N(7)-methyl-GMP


name: SUMOylation of Histone H4 with SUMO1 (Gallus gallus)


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Homo sapiens)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Mus musculus)


name: (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate + 2 H(+) + NADH => 2-hydroxy-5-carboxymethylmuconate semialdehyde + H2O + NAD(+)


name: gibberellin A12 aldehyde + O2 + reduced [NADPH--hemoprotein reductase] => gibberellin A12 + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: (E)-caffeyl aldehyde + CoA + NADP(+) = (E)-caffeoyl-CoA + H(+) + NADPH


name: Phosphorylation of CRMPs by Cdk5 (Danio rerio)


name: ATP + CoA + octanoate <=> AMP + diphosphate + octanoyl-CoA


name: hexacosanoyl-CoA + NADP(+) => (2E)-hexacosenoyl-CoA + H(+) + NADPH


name: NOTCH1 gene expression is inhibited by MECP2 (Homo sapiens)


name: p115-RhoGEF activation of RHOA (Rattus norvegicus)


name: GRK5 sequesters activated Gq (Homo sapiens)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Sus scrofa)


name: 2,3-saturated fatty aldehyde + NADP(+) => (2E)-fatty aldehyde + H(+) + NADPH


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate = 2-(9Z-octadecenoyl)-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: GSTO dimers reduce DeHA to AscH- (Rattus norvegicus)


name: SREBP1A,2 binds the LSS promoter (Homo sapiens)


name: a nitrile + H2O => an aliphatic aldoxime


name: CO2 + gibberellin A14 + H(+) + succinate => 2-oxoglutarate + gibberellin A14 aldehyde + O2


name: holothin + pseudomonoyl-CoA C => CoA + pseudomonic acid C--holothin


name: formate + H(+) + methanol => 2 formaldehyde + H2O


name: Activated AKT phosphorylates RUNX2 (Homo sapiens)


name: diphosphate + prekainate => dimethylallyl diphosphate + L-glutamate


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] => 1,4-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CYP17A1 17-hydroxylates PREG (Homo sapiens)


name: medium-chain fatty acyl-CoA dehydrogenase activity


name: Dissociation of phospho-Cdh1 from the APC/C complex (Drosophila melanogaster)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Sus scrofa)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Homo sapiens)


name: Release of noradrenaline  at the synapse (Caenorhabditis elegans)


name: 4-aminobutanoyl-[BtrI ACP] + CO2 => gamma-L-glutamyl-[BtrI ACP] + H(+)


name: H2O + neurotensin => L-tyrosyl-L-isoleucyl-L-leucine + neurotensin(1-10)


name: 3-O-(5'-adenylyl)-L-threonyl-[protein] + H2O => AMP + H(+) + L-threonyl-[protein]


name: USP5 cleaves polyubiquitin (Rattus norvegicus)


name: D-cellobiono-1,5-lactone + H2O = 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)


name: SOAT1,2 transfer acyl group to CHOL forming CHEST (Rattus norvegicus)


name: ent-cassa-12,15-dien-2beta,3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] => ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Sus scrofa)


name: IL34 dimer binds SDC1 (Rattus norvegicus)


name: "With a quinone or similar compound as acceptor"


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Bos taurus)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Schizosaccharomyces pombe)


name: a jasmonyl-L-amino acid + H2O = a jasmonate + an L-alpha-amino acid


name: 2,4,5-trichlorocyclohexa-2,5-dien-1-ol + chloride + H(+) => (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + H2O


name: RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA (Dictyostelium discoideum)


name: 5beta-cholestane-3alpha,7alpha-diol + O2 + reduced [NADPH--hemoprotein reductase] = 5beta-cholestane-3alpha,7alpha,25-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PELI1 binds activated RIPK1:RIPK3 (Bos taurus)


name: L-threonyl-[protein] + NAD(+) <=> H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-threonyl-[protein]


name: 3-dehydro-L-gulonate 6-phosphate + H(+) = CO2 + L-xylulose 5-phosphate


name: 4-hydroxybenzoate + ATP + holo-[4-hydroxyphenylalkanoate synthase] => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + diphosphate


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Bos taurus)


name: 5alpha-androstane-3beta,17beta-diol + NADP(+) => 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH


name: 5-phosphomethyl-dUMP in DNA + ADP + H(+) => 5-hydroxymethyl-dUMP in DNA + ATP


name: a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester => a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol


name: (R,R)-chrysanthemyl diphosphate + H2O = (R,R)-chrysanthemol + diphosphate


name: Caspase-mediated cleavage of GAS2 (Sus scrofa)


name: 6beta-hydroxycortisone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cortisone + O2 + reduced [NADPH--hemoprotein reductase]


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Plasmodium falciparum)


name: 2-oxoglutarate + L-isoleucine + O2 => (4S)-4-hydroxy-L-isoleucine + CO2 + succinate


name: (9Z,12Z)-octadecadienoate + O2 = (9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: ATP + thiamine diphosphate <=> ADP + thiamine triphosphate


name: 4-hydroxy-3-all-trans-decaprenylbenzoate + H(+) => 2-all-trans-decaprenylphenol + CO2


name: D-ornithine(out) + L-ornithine(in) => D-ornithine(in) + L-ornithine(out)


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Homo sapiens)


name: T1R1/T1R3 dimer is the umami taste receptor (Sus scrofa)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + H(+) + NADPH <=> 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP(+)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Sus scrofa)


name: (3R)-hydroxydodecanoyl-[ACP] + NADP(+) => 3-oxododecanoyl-[ACP] + H(+) + NADPH


name: AH2 + Latia luciferin + 2 O2 <=> A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin


name: Expression of SIX2 in metanephric mesenchyme (Homo sapiens)


name: Translocation of active caspase-8 to the mitochondrial membrane (Homo sapiens)


name: NAALADases hydrolyse NAAG (Canis familiaris)


name: HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12) (Caenorhabditis elegans)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose <=> beta-D-Gal-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: Autophosphorylation of PAK1 (Schizosaccharomyces pombe)


name: Clathrin-mediated endocytosis of DT:HBEGF:CD9 (Homo sapiens)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Caenorhabditis elegans)


name: 2 H(+) + L-pyrrolysine + NADH + NH4(+) => (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + NAD(+)


name: Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)


name: H2O + naphtopyrone YWA1 = acetoacetate + H(+) + naphthalene-1,3,6,8-tetrol


name: Bradykinin receptors B1 and B2 bind to bradykinin (Homo sapiens)


name: H2O + L-seryl-tRNA(Ala) = L-serine + tRNA(Ala)


name: VAV1 is a GEF for Rho/Rac family GTPases (Bos taurus)


name: 7,8-dihydroneopterin 3'-phosphate + H2O => 7,8-dihydroneopterin + phosphate


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Drosophila melanogaster)


name: PI3K synthesizes PIP3 downstream of ALK mutants (Homo sapiens)


name: H2O + lanosteryl ester => a carboxylate + H(+) + lanosterol


name: KDM1A is recruited to MYC and BCL2 genes (Canis familiaris)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Gallus gallus)


name: 2 A + all-trans-4,4'-diapolycopene-4,4'-dial + 2 H2O = 2 AH2 + all-trans-4,4'-diapolycopene-4,4'-dioate + 2 H(+)


name: beta-D-glucosyl crocetin + UDP-alpha-D-glucose = bis(beta-D-glucosyl) crocetin + UDP


name: lorlatinib-resistant ALK mutants don't bind lorlatinib (Homo sapiens)


name: heptan-1-ol + NADP(+) = H(+) + heptanal + NADPH


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)


name: SCARB1:ligand is endocytosed (Mus musculus)


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Mus musculus)


name: a D-glucoside + NAD(+) <=> a 3-dehydro-D-glucoside + H(+) + NADH


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Rattus norvegicus)


name: 2-demethylmenaquinone-8 + H(+) + NADPH = 2-demethylmenaquinol-8 + NADP(+)


name: (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = (11R,12R)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: 4-acetoxybenzyl alcohol + NAD(+) => 4-acetoxybenzaldehyde + H(+) + NADH


name: H2O + N-(9Z-octadecenoyl)-L-glutamine <=> (9Z)-octadecenoate + L-glutamine


name: acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O => D-xylulose 5-phosphate + phosphate


name: 4-hydroxyprotoasukamycin + H2O + NAD(+) => H(+) + NADH + O2 + protoasukamycin


name: NPHP4 protein binds LATS proteins (Canis familiaris)


name: (R)-2-benzylsuccinyl-CoA + succinate => (R)-2-benzylsuccinate + succinyl-CoA


name: SMG6 hydrolyzes mRNA with premature termination codon (Homo sapiens)


name: p-PLINs translocate from lipid droplet surface to cytosol (Homo sapiens)


name: 3-{[(1S,2R,4aR,6R,8aS)-2-(but-2-en-2-yl)-3,4a,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-5-(2-methylpropyl)-2,3-dihydro-1H-pyrrol-2-one + O2 <=> H2O2 + myceliothermophin E


name: Dopamine synaptic vesicle docking and priming (Bos taurus)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Danio rerio)


name: diphosphate + thiamine phosphate => 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+)


name: FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Drosophila melanogaster)


name: PP2A dephosphorylates RAF1 (Homo sapiens)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Sus scrofa)


name: AH2 + O2 + preaustinoid A = A + H2O + preaustinoid A1


name: SUMOylation of TOP2A with SUMO1 (Sus scrofa)


name: O2 + proatranorin I + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin IV


name: CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Rattus norvegicus)


name: D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + H2O => D-glycero-alpha-D-manno-heptose 1-phosphate + phosphate


name: CD isomers transform to BT, BTCA, BZ, ODHBT (Homo sapiens)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Rattus norvegicus)


name: NTP Binds Active Site of RNA Polymerase II (Drosophila melanogaster)


name: XIAP dissociates from ub-TLE (Sus scrofa)


name: I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Rattus norvegicus)


name: (2E)-docosenoyl-CoA + reduced [electron-transfer flavoprotein] => docosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: (R)-carnitine(out) + Na(+)(out) <=> (R)-carnitine(in) + Na(+)(in)


name: phosphate + S-sulfo-L-cysteine => O-phospho-L-serine + thiosulfate


name: pimelyl-[acyl-carrier protein] methyl ester esterase activity


name: LDL translocates from endosome lumen to lysosome lumen (Mus musculus)


name: 3-oxo-2-methylhexadecanoyl-CoA + CoA => propanoyl-CoA + tetradecanoyl-CoA


name: dTDP-alpha-D-glucose => dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O


name: (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + NADP(+)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Canis familiaris)


name: SAICAR => AICAR + Fumarate (Canis familiaris)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: LIPC dimer hydrolyses TAG to DAG and FA (Xenopus tropicalis)


name: UBA1 adenylates ubiquitin in the cytosol (Saccharomyces cerevisiae)


name: H2O + N-acetyl-L-glutamate 5-semialdehyde <=> acetate + L-glutamate 5-semialdehyde


name: PHLPP dephosphorylates S473 in AKT (Rattus norvegicus)


name: Caspase-mediated cleavage of Etk (Mus musculus)


name: ATP binding to HSP90 triggers conformation change (Gallus gallus)


name: angiotensin-(1-9) + L-leucine => angiotensin I + H2O


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: pre-VLDL translocates from RER membrane to SER lumen (Rattus norvegicus)


name: 2 L-ascorbate + N-(9Z,12Z,15Z)-octadecatrienoylglycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = A + H2O + prostaglandin H2


name: (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+) => (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H(+) + NADPH


name: IL20 binds to IL22RA1:JAK1:IL20RB (Canis familiaris)


name: an N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP + H(+) => a ganglioside GM4 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: dAMP(in) + NAD(+)(out) <=> dAMP(out) + NAD(+)(in)


name: (-)-vetispiradiene + diphosphate => (2E,6E)-farnesyl diphosphate


name: RHOD translocates to the Golgi membrane (Homo sapiens)


name: HGSNAT oligomer acetylates Heparan chain(1) (Canis familiaris)


name: L-cysteine(in) + L-phenylalanine(out) = L-cysteine(out) + L-phenylalanine(in)


name: 2-chloro-6-hydroxy-1,4-benzoquinone + 2 chloride + FAD + 3 H(+) => 2,4,6-trichlorophenol + FADH2 + O2


name: SCF-FBXL18 ubiquitinates FBXL7 (Bos taurus)


name: PKC phosphorylates sphingosine kinase 1 (Dictyostelium discoideum)


name: (E)-cinnamate + H(+) + NADPH + O2 <=> H2O + NADP(+) + trans-2-coumarate


name: LINC01139 promotes phosphorylation of HIF1A by PTK6 (Xenopus tropicalis)


name: 4-chlorocatechol + O2 => 3-chloro-cis,cis-muconate + 2 H(+)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Danio rerio)


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Bos taurus)


name: ATP + L-histidyl-[protein] <=> ADP + H(+) + N(tele)-phospho-L-histidyl-[protein]


name: CHEK2 phosphorylates BRCA1 (Homo sapiens)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate <=> 3-hydroxypent-4-ene nitrile + sulfate + sulfur


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Mus musculus)


name: Conversion of Glycerol to Glycerol-3-phosphate (Rattus norvegicus)


name: a dicarboxylate(in) + estrone 3-sulfate(out) => a dicarboxylate(out) + estrone 3-sulfate(in)


name: a D-alpha-amino acid + H2O + O2 => a 2-oxocarboxylate + H2O2 + NH4(+)


name: prostaglandin D2 11-ketoreductase activity


name: Phosphorylation of MEF2 proteins by p38 (Bos taurus)


name: myo-inositol + pyrroloquinoline quinone <=> H(+) + pyrroloquinoline quinol + scyllo-inosose


name: 4-hydroxy-3-all-trans-nonaprenylbenzoate + H(+) = 2-all-trans-nonaprenylphenol + CO2


name: a 1,4-lactone + H2O = a 4-hydroxyacid + H(+)


name: ADP + H(+) + sphinganine 1-phosphate => ATP + sphinganine


name: H2O + phytanoyl-CoA => 3,7,11,15-tetramethylhexadecanoate + CoA + H(+)


name: 4-CDP-2-C-methyl-D-erythritol 2-phosphate => 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Dictyostelium discoideum)


name: 5 (S)-methylmalonyl-CoA + 11 H(+) + malonyl-CoA + 5 NADPH => 10-deoxymethynolide + 6 CO2 + 6 CoA + 2 H2O + 5 NADP(+)


name: protein-phosphocysteine-glucosamine phosphotransferase system transporter activity


name: hexadecan-1-ol + O2 => H2O2 + hexadecanal


name: Cytosolic PLK1 translocates to the nucleus (Rattus norvegicus)


name: H(+)(in) + N-(4-aminobenzoyl)-L-glutamate(in) => H(+)(out) + N-(4-aminobenzoyl)-L-glutamate(out)


name: DNA-directed 5'-3' RNA polymerase activity


name: PTPN12 dephosphorylates EGFR at Y1172 (Y1148) (Sus scrofa)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Mus musculus)


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Rattus norvegicus)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O <=> 1,2-diacyl-sn-glycero-3-phospho-L-serine-N-glycine + [protein]-C-terminal <stereo>L-</stereo>amino acid


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Homo sapiens)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Danio rerio)


name: PKC alpha interacts with and phosphorylates KIT (Homo sapiens)


name: Activation of GIRK/Kir3 Channels (Gallus gallus)


name: cholesteryl octadecanoate + CoA => cholesterol + octadecanoyl-CoA


name: phenylacetyl-coenzyme A:glycine N-acyltransferase activity


name: aldehyde dehydrogenase (quinone) activity


name: glycine + H(+) + tRNA(Ala) => glycyl-tRNA(Ala) + H2O


name: 3-oxohexacosanoyl-CoA + H(+) + NADPH => (3R)-hydroxyhexacosanoyl-CoA + NADP(+)


name: Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) (Homo sapiens)


name: L-iditol + NAD(+) <=> H(+) + keto-L-sorbose + NADH


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Sus scrofa)


name: PTPRF, PTPRS, PTPRD bind Liprins (Drosophila melanogaster)


name: 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine <=> 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: cAMP hydrolysis by Cam-PDE 1 (Canis familiaris)


name: 3,4-dihydroxybenzoate + O2 = 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + H2O => 5-amino-6-(5-phospho-D-ribitylamino)uracil + NH4(+)


name: ROS,RNS oxidize ACO2:4Fe-4S (Sus scrofa)


name: RHOF GAPs stimulate RHOF GTPase activity (Gallus gallus)


name: HOXB4 gene is transcribed (Homo sapiens)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA => (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + malonyl-CoA


name: chenodeoxycholate + lithocholoyl-CoA = chenodeoxycholoyl-CoA + lithocholate


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Canis familiaris)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Bos taurus)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Xenopus tropicalis)


name: LIPC dimer hydrolyses TAG to DAG and FA (Gallus gallus)


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Xenopus tropicalis)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Sus scrofa)


name: malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] (Gallus gallus)


name: angiotensin I + H2O = angiotensin-(1-9) + L-leucine


name: TBC1D25 (OATL1) binds ATG8 homologues (Mus musculus)


name: (1S)-2-methyl-cyclohexylamine + H2O + NADP(+) = 2-methylcyclohexanone + H(+) + NADPH + NH4(+)


name: malonate(in) + sulfate(out) <=> malonate(out) + sulfate(in)


name: delta-tocopherol + S-adenosyl-L-methionine => beta-tocopherol + H(+) + S-adenosyl-L-homocysteine


name: NMRK2 phosphorylates NAR to yield NAMN (Homo sapiens)


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Bos taurus)


name: oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: an aromatic primary alcohol + NAD(+) = an aromatic aldehyde + H(+) + NADH


name: arsenate + D-glyceraldehyde 3-phosphate + NAD(+) = 1-arsono-3-phospho-D-glycerate + H(+) + NADH


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Mus musculus)


name: acetyl-CoA + cortisol => CoA + cortisol 21-acetate


name: Interaction of PAK1 with Rac1-GTP (Canis familiaris)


name: 2-oxoglutarate + hexanoyl-CoA + O2 = 2-hydroxyhexanoyl-CoA + CO2 + succinate


name: NR1H2,3 binds the APOC1 gene (Homo sapiens)


name: 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine => 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine


name: 7,8-dihydroneopterin 3'-triphosphate => 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde triphosphate


name: ATP-dependent chromatin remodeler activity


name: Endocytosis of TGFBR3:ARRB complex (Canis familiaris)


name: ULK3 phosphorylates GLI (Drosophila melanogaster)


name: a menaquinone + succinate => a menaquinol + fumarate


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Drosophila melanogaster)


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Mus musculus)


name: n H(+)(in) + taurocholate(in) => n H(+)(out) + taurocholate(out)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Caenorhabditis elegans)


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + tryptamine => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + serotonin


name: L-serine + taurocholate = L-serocholate + taurine


name: H2O2 oxidises ferrohemoglobin to MetHb (Gallus gallus)


name: alectinib resistant ALK mutants don't bind alectinib (Homo sapiens)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Schizosaccharomyces pombe)


name: butan-1-ol + hexanoyl-CoA = butyl hexanoate + CoA


name: NADK2 dimer phosphorylates NAD+ to NADP+ (Plasmodium falciparum)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Drosophila melanogaster)


name: (5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O => (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2


name: Formation of C-strand Okazaki fragments (Canis familiaris)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Homo sapiens)


name: keto-D-tagatose 6-phosphate => aldehydo-D-galactose 6-phosphate


name: octadecanoyl-CoA + taurine = CoA + H(+) + N-octadecanoyl-taurine


name: Cleavage of Intronless Pre-mRNA at 3'-end (Homo sapiens)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Sus scrofa)


name: PPP1CC dephosphorylates PLK1 (Bos taurus)


name: Transfer of ISG15 from E1 to E2 (UBCH8) (Drosophila melanogaster)


name: 3-phenylpyruvate + L-glutamate => 2-oxoglutarate + L-phenylalanine


name: sulfur:ferric ion oxidoreductase activity


name: phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate (Drosophila melanogaster)


name: 2 H(+) + L-aspartate + 3 NADPH + 3 O2 = 2-nitrobutanedioate + 4 H2O + 3 NADP(+)


name: An unknown BILR reduces BIL to D-UBGN (Homo sapiens)


name: EGFR phosphorylates NOTCH3 (Mus musculus)


name: a 1,3-diacylglycerol + H2O => a 3-acyl-sn-glycerol + a fatty acid + H(+)


name: Activated FGFR2 phosphorylates FRS3 (Gallus gallus)


name: 2-hydroxy-2,3-dihydrogenistein <=> genistein + H(+) + H2O


name: nuclear thyroid hormone receptor binding


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Homo sapiens)


name: H(+) + hexacosanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-hexacosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: I(1,3,4,6)P4 transports from the cytosol to the nucleus (Homo sapiens)


name: PYCARD recruits procaspase-1 via CARD (Homo sapiens)


name: dADP(in) + H(+)(in) + phosphate(out) => dADP(out) + H(+)(out) + phosphate(in)


name: Acireductone is oxidized to MOB (Danio rerio)


name: p52:RELB translocates from cytosol to nucleus (Canis familiaris)


name: gibberellin A12 + 5 H(+) + 3 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => CO2 + gibberellin A9 + 4 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O <=> a 1,2-diacyl-sn-glycerol + phosphate


name: Active LTK binds GRB2:TNK2 (Mus musculus)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-alkyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine + H(+)


name: 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = alpha-D-glucose 1-phosphate + D-gluconate


name: tryptophan hydroxylase activator activity


name: IFN alpha/beta binds to IFNAR2 (Gallus gallus)


name: USP13 and OTUD3 deubiquitinate PTEN (Gallus gallus)


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Bos taurus)


name: D-cellopentaonate + H(+) => D-cellopentaono-1,5-lactone + H2O


name: H(+) + N-octadecanoylsphing-4-enine + phosphocholine => H2O + N-(octadecanoyl)-sphing-4-enine-1-phosphocholine


name: benzoyl-CoA + H2O + oxidized 2[4Fe-4S]-[ferredoxin] => 4-hydroxybenzoyl-CoA + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Schizosaccharomyces pombe)


name: 4-aminoimidazole + H(+) + H2O => imidazol-4-one + NH4(+)


name: NEIL2 recognizes and binds 5-OHU-dsDNA (Homo sapiens)


name: TFR2 dimer binds 2xholoTF (Homo sapiens)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Mus musculus)


name: PP2A-B56 dephosphorylates centromeric cohesin (Sus scrofa)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Dictyostelium discoideum)


name: (S)-malate(in) + succinate(out) => (S)-malate(out) + succinate(in)


name: Glucagon-like receptor 2 binds GLP2 (Bos taurus)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + 2 O2 <=> (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E)-docosapentaenoate


name: L-serine + taurocholate <=> L-serocholate + taurine


name: ABCB9 transports peptides from cytosol to lysosomal lumen (Caenorhabditis elegans)


name: MITF-M-dependent BIRC7 gene expression (Homo sapiens)


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Canis familiaris)


name: GLI proteins bind SUFU (Xenopus tropicalis)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Sus scrofa)


name: glycocholate + L-histidine => glycine + L-histidocholate


name: FAM83B, (FAM83A, FAM83D) bind EGFR (Sus scrofa)


name: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H(+)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Sus scrofa)


name: TGFBR3_mem cleavage by MMPs (Rattus norvegicus)


name: CD274 gene expression downstream of ALK signaling (Homo sapiens)


name: SAR1 Activation And Membrane Binding (Plasmodium falciparum)


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Rattus norvegicus)


name: 3 (S)-methylmalonyl-CoA + a long-chain fatty acyl-CoA + 9 H(+) + holo-[mycolipanoate synthase] + 6 NADPH <=> 3 CO2 + 4 CoA + 3 H2O + long-chain mycolipanoyl-[mycolipanoate synthase] + 6 NADP(+)


name: P4HB mediates disulfide bond formation in Proinsulin (Sus scrofa)


name: RNF146 binds RibC-AXIN:TNKS complex (Sus scrofa)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Xenopus tropicalis)


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Homo sapiens)


name: ATP + beta-D-fructose 6-phosphate <=> ADP + beta-D-fructose 2,6-bisphosphate + H(+)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Homo sapiens)


name: (5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+)


name: abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase] = abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetoacetate(out) + H(+)(out) => acetoacetate(in) + H(+)(in)


name: Caspase-9 binds DCC:DIP13alpha complex (Mus musculus)


name: (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA + H2O => (3R)-hydroxy-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA


name: (R)-4-phosphopantoate + ADP + H(+) => (R)-pantoate + ATP


name: SALM2 associate with AMPA and NMDA receptors (Bos taurus)


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Bos taurus)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Saccharomyces cerevisiae)


name: 2 Fe(II)-[cytochrome c] + fumarate + 2 H(+) => 2 Fe(III)-[cytochrome c] + succinate


name: ADP + thiamine diphosphate <=> AMP + thiamine triphosphate


name: S-adenosyl-L-methionine + tyramine = H(+) + N-methyltyramine + S-adenosyl-L-homocysteine


name: H(+)(out) + malonate(in) + phosphate(out) => H(+)(in) + malonate(out) + phosphate(in)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + acetyl-CoA <=> 1-O-(1Z)-alkenyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: SLC25A1 exchanges CIT and MAL (Caenorhabditis elegans)


name: H(+)(in) + shikimate(in) => H(+)(out) + shikimate(out)


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-delta-cadinol + diphosphate


name: Activation of STAT5a/b by JAK2 (Bos taurus)


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Mus musculus)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 1-O-methyl-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: apo-[D-alanyl-carrier protein] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[D-alanyl-carrier protein]


name: SMURF1/2 dissociates from ub-PTCH1 (Canis familiaris)


name: 17alpha-hydroxypregnenolone 3-sulfate(out) + 2 Na(+)(out) = 17alpha-hydroxypregnenolone 3-sulfate(in) + 2 Na(+)(in)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Drosophila melanogaster)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Rattus norvegicus)


name: transmembrane receptor protein tyrosine kinase inhibitor activity


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Caenorhabditis elegans)


name: Trimerization of HSF1 in the nucleus (Saccharomyces cerevisiae)


name: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)


name: NADP(+) + prostaglandin I2 => 15-dehydro-prostaglandin I2 + H(+) + NADPH


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-N-(acetyl)-sphing-4-enine


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + sphing-4-enine => 1-O-alkyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine + H(+)


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Bos taurus)


name: 2-oxoglutarate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate


name: NAGLU hydrolyses Heparan sulfate chain(4) (Rattus norvegicus)


name: CYP21A2 21-hydroxylates PROG (Bos taurus)


name: apigenin 4',7-dimethyl ether + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + ladanein + oxidized [NADPH--hemoprotein reductase]


name: Activated human JNKs migrate to nucleoplasm (Rattus norvegicus)


name: Activated FGFR3 phosphorylates SHC1 (Drosophila melanogaster)


name: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate


name: androst-5-ene-diol 3-sulfate(in) + 2 Na(+)(in) => androst-5-ene-diol 3-sulfate(out) + 2 Na(+)(out)


name: ATAT acetylates microtubules (Canis familiaris)


name: SLC17A3-2 transports cytosolic urate to extracellular region (Mus musculus)


name: Role of myosins in phagosome formation (Sus scrofa)


name: H2O + methylglyoxal + O2 => H(+) + H2O2 + pyruvate


name: (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-glutamate => (6S)-5-formyl-5,6,7,8-tetrahydrofolate + L-glutamate


name: UDP-glucose transmembrane transporter activity


name: 2-oxobutanoate + N(omega),N(omega)-dimethyl-L-arginine => (2S)-2-aminobutanoate + 5-(3,3-dimethylguanidino)-2-oxopentanoate


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Canis familiaris)


name: acetaldehyde dehydrogenase (acetylating) activity


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Drosophila melanogaster)


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Homo sapiens)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Danio rerio)


name: glutathione(out) + leukotriene C4(in) => glutathione(in) + leukotriene C4(out)


name: (6R)-L-erythro-6,7-dihydrobiopterin + (S)-4-hydroxymandelate + H2O => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + (S)-mandelate + O2


name: 2-dehydro-3-deoxy-L-rhamnonate + H2O => L-rhamnonate


name: an R-cob(III)alamin(out) + ATP + H2O <=> ADP + an R-cob(III)alamin(in) + H(+) + phosphate


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)


name: 2 ADP + cyclo(L-tryptophyl-L-alanyl) + 2 H(+) + 2 phosphate => 2 ATP + L-alanine + L-tryptophan


name: a ganglioside GD3 + H2O => a ganglioside GM3 + N-acetylneuraminate


name: ATP + N(6)-(D-fructosyl)-L-lysyl-[protein] <=> ADP + H(+) + N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein]


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Rattus norvegicus)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Danio rerio)


name: 4-imidazolone-5-propanoate + H2O <=> N-formimidoyl-L-glutamate


name: FLAD1 phosphorylates FMN (Drosophila melanogaster)


name: 5-(carboxymethyl)uridine(34) in tRNA + S-adenosyl-L-methionine => 5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA + S-adenosyl-L-homocysteine


name: SLC16A10-mediated uptake of aromatic amino acids (Xenopus tropicalis)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Cytoslic carboxylases translocate to mitochondrial matrix (Saccharomyces cerevisiae)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Homo sapiens)


name: HHAT palmitoylates Hh N-terminal fragment (Mus musculus)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Caenorhabditis elegans)


name: SUMOylation of TFAP2A with SUMO1 (Homo sapiens)


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Homo sapiens)


name: alpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + GDP + H(+) => a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E)) + GDP-beta-L-fucose


name: STAT1,STAT3,STAT6 bind IL13:IL13R type II (Gallus gallus)


name: anthocyanin A7 + malonyl-CoA => anthocyanin A9 + CoA


name: 2 dihydrogeodin + 2 H(+) + O2 = 2 (+)-geodin + 2 H2O


name: estrone 3-sulfate(in) + H(+)(out) = estrone 3-sulfate(out) + H(+)(in)


name: Furin cleaves pro-factor X to factor X (Gallus gallus)


name: H2O + N(6)-(6-phospho-D-fructosyl)-L-lysine => D-glucose 6-phosphate + L-lysine


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: crocetin + UDP-alpha-D-glucose => beta-D-glucosyl crocetin + UDP


name: H(+)(out) + L-phenylalanyl-L-leucine(out) => H(+)(in) + L-phenylalanyl-L-leucine(in)


name: cholesterol + NADP(+) => desmosterol + H(+) + NADPH


name: 1,4-dihydroxy-6-naphthoate + dihydroxyacetone => cyclic dehypoxanthinylfutalosinate


name: (8Z,11Z,14Z)-eicosatrienoate + O2 = 11-hydroperoxy-(8Z,12E,14Z)-eicosatrienoate


name: CDK1 phosphorylates MAPK6 (Canis familiaris)


name: DENND3 exchanges GTP for GDP on RAB12 (Rattus norvegicus)


name: H(+) + H2O + urethane = CO2 + ethanol + NH4(+)


name: CHRM4 binds CHRM4 antagonists (Xenopus tropicalis)


name: SARS-CoV-2 nsp6 binds TBK1 (Homo sapiens)


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Canis familiaris)


name: RHOT1 GEFs activate RHOT1 (Homo sapiens)


name: Release of GABA at the synapse (Rattus norvegicus)


name: Binding of RRN3 to RNA Polymerase I (Saccharomyces cerevisiae)


name: ATP + di-trans,octa-cis-undecaprenol <=> ADP + di-trans,octa-cis-undecaprenyl phosphate + H(+)


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Gallus gallus)


name: Dopa is oxidized to dopaquinone by TYR (Xenopus tropicalis)


name: H2O + juglone <=> naphthalene-1,2,4,8-tetrol


name: α1-agonists bind ADRA1A,B,D (Canis familiaris)


name: 3-hydroxyindolin-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => indolin-2-one + O2 + reduced [NADPH--hemoprotein reductase]


name: glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Canis familiaris)


name: (S)-scoulerine + 2-oxoglutarate + O2 <=> (S)-3-O-demethylscoulerine + CO2 + formaldehyde + succinate


name: H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1191) in yeast 18S rRNA + S-methyl-5'-thioadenosine


name: DENND3 exchanges GTP for GDP on RAB12 (Bos taurus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Sus scrofa)


name: CES1,CES2 hydrolyze ASA- to ST (Canis familiaris)


name: CysS248-MPST:TXN2 dissociates (Bos taurus)


name: PDK isozymes phosphorylate PDHC subunit E1 (Caenorhabditis elegans)


name: 2 L-glutamate + NADP(+) => 2-oxoglutarate + H(+) + L-glutamine + NADPH


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Drosophila melanogaster)


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate => a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Homo sapiens)


name: Expression of peptide bound class I MHC on cell surface (Mus musculus)


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Xenopus tropicalis)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Sus scrofa)


name: Activated ATM phosphorylates DCLRE1C (Homo sapiens)


name: Edited Kainate Receptor binds glutamate (Gallus gallus)


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine


name: Dopachrome is transformed to DHICA by DCT (Rattus norvegicus)


name: D-mannonate + NADP(+) => D-mannuronate + H(+) + NADPH


name: acetaldehyde + chemical entity + H(+) + nitrite => ethylnitronate + O2


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Rattus norvegicus)


name: a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Polyubiquitination of substrate (Danio rerio)


name: SETD6 methylates RELA in the NFkB complex (Rattus norvegicus)


name: dUTP(in) + UTP(out) => dUTP(out) + UTP(in)


name: 27-hydroxysterol binds ESR1, ESR2 (Drosophila melanogaster)


name: maleate(out) + sulfate(in) => maleate(in) + sulfate(out)


name: SCUBE1, SCUBE3 oligomerize (Canis familiaris)


name: SUMOylation of NPM1 with SUMO2,3 (Rattus norvegicus)


name: 3-(4-hydroxyphenyl)pyruvate + O2 = CO2 + homogentisate


name: L-phenylalanine = (E)-cinnamate + NH4(+)


name: Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Gallus gallus)


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Canis familiaris)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Homo sapiens)


name: Growing HA is extruded from the cell by ABCC5 (Caenorhabditis elegans)


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Bos taurus)


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Sus scrofa)


name: IL12A gene transcription and translation (Homo sapiens)


name: ATP + UTP => 3',3'-cUAMP + 2 diphosphate


name: CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate (Homo sapiens)


name: ATP + decanoate + H(+) = decanoyl-AMP + diphosphate


name: 1-O-alkyl-sn-glycero-3-phosphate + NADP(+) => 1-O-alkylglycerone 3-phosphate + H(+) + NADPH


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Danio rerio)


name: (9Z,12Z)-octadecadienoate + H2O => (12Z)-10-hydroxyoctadecenoate


name: p-T,Y MAPK dimers translocate to nucleus (Bos taurus)


name: citrate(in) + fumarate(out) => citrate(out) + fumarate(in)


name: 2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+)


name: SIRPA binds SFTPA oligomer, SFTPD oligomer (Canis familiaris)


name: SEMA4D interacts with CD72 (Homo sapiens)


name: (3S)-hydroxy-(9Z-octadecenoyl)-CoA + NAD(+) => 3-oxo-(9Z-octadecenoyl)-CoA + H(+) + NADH


name: Tyrosine phosphorylation of CRMPs by Fes (Rattus norvegicus)


name: [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] <=> [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Mus musculus)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Dictyostelium discoideum)


name: H2O + L-cysteinyl-tRNA(Cys) <=> H(+) + L-cysteine + tRNA(Cys)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: KDSR reduces 3-ketosphingoid (Sus scrofa)


name: AXL autophosphorylates on Y779 and Y821 (Bos taurus)


name: FA2H hydroxylates 1,2-saturated fatty acids (Xenopus tropicalis)


name: PLB1 hydrolyses RPALM to atROL (Gallus gallus)


name: 12-methyloctadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-(11-methylheptadecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: [glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O


name: DHRS7B reduces GO3P to HXDG3P (Homo sapiens)


name: RAC2 translocates to the mitochondrial membrane (Gallus gallus)


name: 3'-O-methyltricetin O methyl transferase activity


name: H2O + O-phospho-L-homoserine = L-threonine + phosphate


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Activation of RAC1 by the PXN:CRK complex (Danio rerio)


name: H(+) + N-methylphenylethanolamine + S-adenosyl-L-homocysteine => phenylethanolamine + S-adenosyl-L-methionine


name: REST recruits the BHC complex (Gallus gallus)


name: 4-hydroxy-L-threonine => glycine + glycolaldehyde


name: Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Rattus norvegicus)


name: 2-oxoglutarate + H(+) + NADH + NH4(+) => H2O + L-glutamate + NAD(+)


name: Protein 3a forms a homotetramer (Homo sapiens)


name: a long-chain fatty acid + ATP + L-cysteinyl-[protein] => AMP + diphosphate + S-(long-chain fatty acyl)-L-cysteinyl-[protein]


name: an aliphatic nitrile + 2 H2O => a carboxylate + NH4(+)


name: CoA + H(+) + N-hexanoyltyramine => hexanoyl-CoA + tyramine


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Rattus norvegicus)


name: (S)-lactaldehyde + NADP(+) <=> H(+) + methylglyoxal + NADPH


name: H2O + N,N-dimethylformamide => dimethylamine + formate


name: XDH dehydrogenates hypoxanthine to form xanthine (Rattus norvegicus)


name: CERT1-2 complex dissociates (Bos taurus)


name: 2-oxoglutarate + an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + O2 <=> a 2-hydroxyornithine lipid + CO2 + succinate


name: 3'-phosphoadenylyl sulfate + 3beta-androst-5-en-17-one 3-O-(beta-D-glucuronate) <=> 3beta-androst-5-en-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate => S-methyl-5-thio-D-ribulose 1-phosphate


name: Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Danio rerio)


name: AH2 + H(+) + hydroxylamine => A + H2O + NH4(+)


name: Factor Xa inhibitors binds Xa (Homo sapiens)


name: (2R)-ethylmalonyl-CoA + ADP + H(+) + phosphate => ATP + butanoyl-CoA + hydrogencarbonate


name: L-methionine(in) + Na(+)(in) = L-methionine(out) + Na(+)(out)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Mus musculus)


name: 2,3-dioctanoyl-sn-glycerol + H(+) + octanoate => 1,2,3-trioctanoylglycerol + H2O


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Mus musculus)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Drosophila melanogaster)


name: NTRK3 dimers trans-autophosphorylate (Rattus norvegicus)


name: (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H(+) + NADPH = (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: (9Z)-octadecenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphate => 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Mus musculus)


name: The exocyst complex binds to RAB3IP in the ciliary targeting complex (Canis familiaris)


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Canis familiaris)


name: CREB3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Homo sapiens)


name: CHUK, IKBKB phosphorylate RIPK1 at S25 (Sus scrofa)


name: H(+)(out) + NADH + NADP(+) => H(+)(in) + NAD(+) + NADPH


name: Auto-ubiquitination of TRAF3 within activated TLR3 complex (Homo sapiens)


name: LUBAC ubiquitinates CFLAR at K351, K353 (Homo sapiens)


name: (9Z)-octadecenoate + 9-hydroxy-octadecanoate + H(+) => 9-(9Z-octadecenoyloxy)-octadecanoate + H2O


name: Exocytosis of secretory granule lumen proteins (Homo sapiens)


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Danio rerio)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Gallus gallus)


name: ER calcium channels open in response to activated PKA (Drosophila melanogaster)


name: Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)


name: 2 H(+) + O2 + pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-ol


name: H2O + isopentenyl diphosphate = H(+) + isopentenyl phosphate + phosphate


name: 3-dehydro-D-glucose + D-glucose => 3-dehydro-alpha,alpha-trehalose + H2O


name: RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Drosophila melanogaster)


name: VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)


name: 9beta-pimara-7,15-dien-19-al + O2 + reduced [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-dien-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated PTK6 binds CDKN1B (Homo sapiens)


name: Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Bos taurus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: EP1 receptor can bind PGE2 (Rattus norvegicus)


name: (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADPH = (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+)


name: RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants (Homo sapiens)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)


name: 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA <=> 1-octanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Sus scrofa)


name: PAK1 phosphorylates myosin phosphatase (Bos taurus)


name: Recruitment of Telomerase RNP to the Telomeric Chromosome End (Bos taurus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4 (Canis familiaris)


name: ATP + N(1)-(3,4-dihydroxybenzoyl)-N(8)-citryl-spermidine + spermidine <=> AMP + diphosphate + H(+) + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine)


name: (3beta)-hydroxy-cholest-5-en-26-al + NADPH + O2 <=> (3beta)-hydroxy-cholest-5-en-26-oate + H2O + NADP(+)


name: Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Xenopus tropicalis)


name: Syk activation leads to SLP-76 activation (Sus scrofa)


name: MYSM1 deubiquitinates Histone H2A (Xenopus tropicalis)


name: catechol + O2 => (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H(+)


name: Phosphorylated FOXO1A is excluded from the nucleus (Drosophila melanogaster)


name: 3'-phosphoadenylyl sulfate + estrone 3-O-(beta-D-glucuronate) <=> adenosine 3',5'-bisphosphate + estrone 3-O-(3-sulfo-beta-D-glucuronate) + H(+)


name: N(alpha)-acetyl-L-methionine + N-terminal L-glutamyl-[protein] => H2O + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein]


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Canis familiaris)


name: (R)-laudanine + H(+) + S-adenosyl-L-homocysteine => (R)-reticuline + S-adenosyl-L-methionine


name: ST8SIA5 transfers Neu5Ac to gangliosides (Homo sapiens)


name: ethanol + N,N-dimethyl-4-nitrosoaniline = 4-(hydroxylamino)-N,N-dimethylaniline + acetaldehyde


name: NGEF exchanges GTP for GDP on RHOA (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane (Homo sapiens)


name: RUNX1 binds the CR1 gene promoter (Homo sapiens)


name: Activated FGFR2 phosphorylates FRS3 (Bos taurus)


name: 7-methylmellein + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 7-carboxymellein + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Type XII and XIV collagens associate with type I and type II fibrils. (Sus scrofa)


name: cyclobutadithymidine in DNA => a thymidine dimer in DNA


name: Unwinding DNA for the nascent transcript (Mus musculus)


name: Import of PIC to the Host Nucleus (Homo sapiens)


name: H2O + sphing-4-enine-phosphocholine <=> H(+) + phosphocholine + sphing-4-enine


name: 3 S-adenosyl-L-methionine + tricetin = 3',4',5'-O-trimethyltricetin + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: SLC2A5 transports fructose from extracellular region to cytosol (Drosophila melanogaster)


name: a (2R,3S)-2-alkyl-3-hydroxyalkanoate + ATP = a cis-3-alkyl-4-alkyloxetan-2-one + AMP + diphosphate


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Canis familiaris)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Gallus gallus)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Caenorhabditis elegans)


name: ATP + domoate(in) + H2O => ADP + domoate(out) + H(+) + phosphate


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Drosophila melanogaster)


name: ADP + H(+) + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysine => ATP + N(6)-(D-erythrulosyl)-L-lysine


name: (S)-1-phenylethylamine + H2O + NAD(+) => acetophenone + H(+) + NADH + NH4(+)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Rattus norvegicus)


name: 2-oxobutanoate + H(+) + hydrogen sulfide + NH4(+) => H2O + L-homocysteine


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Danio rerio)


name: Receptor FFAR3 binds carboxylates (Rattus norvegicus)


name: alpha-santonin + H(+) + NADPH => 1,2-dihydro-alpha-santonin + NADP(+)


name: PLK2 phosphorylates NPM1 (Xenopus tropicalis)


name: H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate


name: steviol + UDP-alpha-D-glucose <=> H(+) + steviolmonoside + UDP


name: (R)-3-hydroxy-2-methylpropanoate + NAD(+) <=> (R)-2-methyl-3-oxopropanoate + H(+) + NADH


name: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate


name: an N-acyl-sphingoid base + beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-D-Glc => a ganglioside GM1 + H2O


name: (+)-isoborneol + NAD(+) <=> (1S,4S)-camphor + H(+) + NADH


name: JAK2-activated MAPKs phosphorylate YBX1 (Rattus norvegicus)


name: HCCS inserts heme into cytochrome c (Canis familiaris)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP => delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-alpha-D-glucose


name: H(+) + NAD(+) + reduced 2[4Fe-4S]-[ferredoxin] = NADH + oxidized 2[4Fe-4S]-[ferredoxin]


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Caenorhabditis elegans)


name: galactarate => (2S,3R)-dihydroxy-5-oxohexanedioate + H2O


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Schizosaccharomyces pombe)


name: divinyl chlorophyllide a 8-vinyl-reductase activity


name: NAD(+) + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate = H(+) + NADH + UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate


name: formaldehyde + H2O + N-methyl-L-proline + NADP(+) => H(+) + L-proline betaine + NADPH + O2


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Plasmodium falciparum)


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Drosophila melanogaster)


name: PRDM9 binds recombination hotspot motifs in DNA (Homo sapiens)


name: 7-cyano-7-carbaguanosine(15) in tRNA + H2O + L-glutamine <=> archaeosine(15) in tRNA + L-glutamate


name: p130 (RBL2) associates with MuvB to form DREAM complex (Xenopus tropicalis)


name: (E)-non-2-enal + H2O + NAD(+) => (E)-non-2-enoate + 2 H(+) + NADH


name: Prolactin-releasing hormone receptor binds PRH (Canis familiaris)


name: STAT1 and STAT3 dimers translocate to the nucleus (Danio rerio)


name: Endosomal TLRs pass through the Golgi (Bos taurus)


name: a ganglioside GA2 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GM2 (d18:1(4E)) + H2O


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Rattus norvegicus)


name: Defective SLC20A2 does not cotransport Pi, Na+ from extracellular region to cytosol (Homo sapiens)


name: (E)-sinapate + UDP-alpha-D-glucose => 1-O-(trans-sinapoyl)-beta-D-glucose + UDP


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + CO2 + CoA


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Mus musculus)


name: N(6)-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] => L-lysyl-[protein] + methylglyoxal


name: 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + O2 <=> CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate


name: 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + L-aspartate 4-semialdehyde => 2,3-dioxopropyl phosphate + 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate


name: p-T774-PKN1 phosphorylates PPP1R14A (Caenorhabditis elegans)


name: indole-3-acetonitrile nitrile hydratase activity


name: 3-hydroxypentacecilide A + H(+) + NADPH + O2 <=> chrodrimanin F + H2O + NADP(+)


name: an N-acylsphing-4-enine + UDP-alpha-D-galactose <=> H(+) + N-acyl-D-galactosylsphing-4-enine + UDP


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Rattus norvegicus)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Canis familiaris)


name: Disassociation of CLIP from MHC II (Bos taurus)


name: GP1BA variant binds to VWF multimer:collagen (Homo sapiens)


name: neryl diphosphate + olivetolate <=> cannabinerolate + diphosphate


name: RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)


name: (R)-carnitine(out) + O-octanoyl-(R)-carnitine(in) => (R)-carnitine(in) + O-octanoyl-(R)-carnitine(out)


name: SMAD7:NEDD4L complex translocates to the cytosol (Homo sapiens)


name: 2 formate + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 2 CO2 + H(+) + NADH + 2 reduced [2Fe-2S]-[ferredoxin]


name: ectocarpin A + H2O => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: GSDME (1-270) binds cardiolipin (Homo sapiens)


name: alpha,alpha-trehalose 6-phosphate + GDP + H(+) => D-glucose 6-phosphate + GDP-alpha-D-glucose


name: a 2'-deoxyadenosine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + O2


name: BLT receptors can bind LTB4 (Mus musculus)


name: p-STAT1dimer:KPNA1 binds KPNB1 (Homo sapiens)


name: PIAS1 SUMOylates NR2C1 (TR2) (Homo sapiens)


name: (E)-4-hydroxynon-2-en-1-ol + NAD(+) = (E)-4-hydroxynon-2-enal + H(+) + NADH


name: 1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: 3-methylbutanoate + ATP + CoA <=> 3-methylbutanoyl-CoA + AMP + diphosphate


name: Keratin filament formation (Mus musculus)


name: a 5'-end diphospho-guanosine in mRNA + GTP + H(+) <=> a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + diphosphate


name: Orexin 2 receptor can bind orexin-B neuropeptide (Homo sapiens)


name: ERKs are inactivated by protein phosphatase 2A (Homo sapiens)


name: 4-(trimethylamino)butanoate + 2 H(+) + NADH => 4-(trimethylamino)butanal + H2O + NAD(+)


name: (2E,4E)-tetradecadienoyl-CoA + H(+) + NADPH => (3E)-tetradecenoyl-CoA + NADP(+)


name: D-apionolactone + H(+) + NADH => D-apiofuranose + NAD(+)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Drosophila melanogaster)


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Sus scrofa)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Xenopus tropicalis)


name: SEPHS2 phosphorylates H2Se to form SELP (Dictyostelium discoideum)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Rattus norvegicus)


name: ERO1B oxidizes P4HB (Caenorhabditis elegans)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Bos taurus)


name: Activation of Rap1 by cytosolic GEFs (Homo sapiens)


name: an acyl-CoA + sn-glycerol 3-phosphate <=> a 1-acyl-sn-glycero-3-phosphate + CoA


name: high molecular weight kininogen receptor binding


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxyhexacosanoyl)-sphinganine <=> a 1,2-diacyl-sn-glycerol + Ins-1-P-Cer(d18:0/2-OH-26:0)


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Dictyostelium discoideum)


name: IKKε (IKBKE) is phosphorylated within the activated TLR3 complex (Homo sapiens)


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Rattus norvegicus)


name: ATP + CoA + malonate <=> AMP + diphosphate + malonyl-CoA


name: ANKLE2 is deacetylated by SIRT2 (Danio rerio)


name: estrone + PAPS => estrone 3-sulfate + PAP (Rattus norvegicus)


name: (S)-carvone + AH2 => (1R,4S)-isodihydrocarvone + A


name: dimethyl sulfoxide + menaquinol-8 = dimethyl sulfide + H2O + menaquinone-8


name: HSD17B13 binds lipid droplets (Homo sapiens)


name: AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Canis familiaris)


name: ATP + L-lombricine = ADP + H(+) + N-phospho-L-lombricine


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Sus scrofa)


name: Recruitment of POLB to the AP site (Sus scrofa)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Bos taurus)


name: cytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Gly)(GCC) + H(+) + S-adenosyl-L-homocysteine


name: PGRMC2:Hemes dissociates (Schizosaccharomyces pombe)


name: L1-EGFR trans-heterodimerization (Mus musculus)


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Canis familiaris)


name: P-selectin binds P-selectin ligand (Bos taurus)