name: digoxin + 2 Fe(II)-[cytochrome c] + 3 H(+) = dihydrodigoxin + 2 Fe(III)-[cytochrome c]


name: (S)-1-pyrroline-5-carboxylate + 2 H2O + NAD(+) <=> H(+) + L-glutamate + NADH


name: prostaglandin E2(in) => prostaglandin E2(out)


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Plasmodium falciparum)


name: 1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol = an alkyl cinnamate + beta-D-glucose


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Saccharomyces cerevisiae)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Sus scrofa)


name: (5E)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,5E)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: L-olivosyl-oleandolide + S-adenosyl-L-methionine = H(+) + L-oleandrosyl-oleandolide + S-adenosyl-L-homocysteine


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3A (GRIN3A) (Homo sapiens)


name: SUMOylation of Histone H4 with SUMO3 (Rattus norvegicus)


name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA (Danio rerio)


name: Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Sus scrofa)


name: acetate + L-2,4-diaminobutanoate => (2S)-2-acetamido-4-aminobutanoate + H2O


name: H2O + 2 O2 + thiamine => H(+) + 2 H2O2 + thiamine acetate


name: ATP + glycyl-L-glutamine(out) + H2O <=> ADP + glycyl-L-glutamine(in) + H(+) + phosphate


name: ATP + CoA + propanoate <=> AMP + diphosphate + propanoyl-CoA


name: JMJD6 demethylates Me2R3-histone H3 (Rattus norvegicus)


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + S-adenosyl-L-methionine = a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide + H(+) + S-adenosyl-L-homocysteine


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Homo sapiens)


name: mTORC1 phosphorylates MAF1 (Mus musculus)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Bos taurus)


name: DVL is recruited to the receptor (Xenopus tropicalis)


name: 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH2 => A + H2O + quinoline-4-carboxylate


name: ATP + L-fucose <=> ADP + beta-L-fucose 1-phosphate + H(+)


name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Bos taurus)


name: (R)-4'-phosphopantetheine + H2O => (R)-pantetheine + phosphate


name: Disassembly of the destabilised 'destruction complex' (Drosophila melanogaster)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Schizosaccharomyces pombe)


name: IFN alpha/beta binds to IFNAR2 (Rattus norvegicus)


name: H(+) + N,N-dihydroxy-L-tetrahomomethionine <=> (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O


name: ATP + L-glutamate + oxidized coenzyme F420-2 <=> ADP + H(+) + oxidized coenzyme alpha-F420-3 + phosphate


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) => 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP


name: a beta-D-galactoside + acetyl-CoA <=> a 6-acetyl-beta-D-galactoside + CoA


name: (1R,2S)-ephedrine + NAD(+) => (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Rattus norvegicus)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Sus scrofa)


name: SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Rattus norvegicus)


name: TPMT transfers methyl group to 6TIMP, forming 6MeTIMP (Sus scrofa)


name: (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-dihomomethionine


name: ATP + L-glutamate + L-glutamyl-[tubulin] => ADP + gamma-L-glutamyl-L-glutamyl-[tubulin] + H(+) + phosphate


name: CoA + ergosteryl ester => an acyl-CoA + ergosterol


name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (Drosophila melanogaster)


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)


name: P-selectin binds P-selectin ligand (Mus musculus)


name: FMN + H(+) + oxidized coenzyme F420-0 => dehydro coenzyme F420-0 + FMNH2


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 4 H2O + 3 NAD(+) => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H(+) + 3 NADH + 3 O2


name: L-aspartate(out) + succinate(in) => L-aspartate(in) + succinate(out)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+) => a 1,2-diacyl-sn-glycerol + CDP-ethanolamine


name: 5'-deoxyadenosine + a 7(1)-hydroxybacteriochlorophyllide c + H(+) + L-methionine => a bacteriochlorophyllide c + H2O + S-adenosyl-L-methionine


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Mus musculus)


name: P4HB binds Collagen chains (Caenorhabditis elegans)


name: 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Rattus norvegicus)


name: SLC6A15-mediated amino acid uptake (Canis familiaris)


name: H(+) + NAD(+) + reduced [4Fe-4S]/[3Fe-4S]-[ferredoxin] = NADH + oxidized [4Fe-4S]/[3Fe-4S]-[ferredoxin]


name: EBI3:CANX binds IL12A (Rattus norvegicus)


name: H2O + N-acetyltyramine => acetate + tyramine


name: 3-methylbutanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 3 CO2 + 4 CoA + phlorisovalerophenone


name: SHC1 binds P-ERBB4 isoform dimers (Homo sapiens)


name: (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H(+) + NADPH <=> (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: diglucosyl-enterobactin + UDP-alpha-D-glucose => H(+) + triglucosyl-enterobactin + UDP


name: SIRT4 transfers ADPRib to GLUD (Gallus gallus)


name: MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate => (+)-cubenene + diphosphate


name: Proteasomal cleavage of substrate (Homo sapiens)


name: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome (Bos taurus)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Rattus norvegicus)


name: HGD dioxygenates homogentisate (Drosophila melanogaster)


name: Fillagrin and keratin intermediate filaments polymerize forming a network (Danio rerio)


name: ATP + thiamine => AMP + H(+) + thiamine diphosphate


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Drosophila melanogaster)


name: a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + H(+) + S-adenosyl-L-homocysteine


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Drosophila melanogaster)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 => (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: Inactive RAFs bind YWHAB (Gallus gallus)


name: a nucleoside 3',5'-cyclic phosphate + H2O => a nucleoside 5'-phosphate + H(+)


name: a monoamide of a dicarboxylate + H2O <=> a dicarboxylate + NH4(+)


name: CD28 homodimer binds B7-2 monomer (Sus scrofa)


name: Opioid receptors bind opioid peptides (Bos taurus)


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Dictyostelium discoideum)


name: 9-cis-retinal + H2O + NAD(+) => 9-cis-retinoate + 2 H(+) + NADH


name: DHODH:FMN binds DHODH inhibitors (Sus scrofa)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Canis familiaris)


name: SLC6A4 binds TCAs and SSRIs (Canis familiaris)


name: RHCE gene produces Rhesus C or E proteins (Homo sapiens)


name: MAOA inhibitors bind MAOA:FAD (Rattus norvegicus)


name: 26S proteasome degrades HIFalpha (Canis familiaris)


name: (2R,3S)-dihydrodehydrodiconiferyl alcohol + H(+) + NADPH => (S)-tetrahydrodehydrodiconiferyl alcohol + NADP(+)


name: PIAS1 SUMOylates SAFB with SUMO1 (Bos taurus)


name: PDE4A hydrolyses cAMP to AMP (Sus scrofa)


name: phosphate + sucrose 6(F)-phosphate = alpha-D-glucose 1-phosphate + beta-D-fructose 6-phosphate


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Drosophila melanogaster)


name: HV1-mediated H+ transfer (Xenopus tropicalis)


name: O2 + reduced [NADPH--hemoprotein reductase] + taxusin => 7beta-hydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetyl-CoA + N-terminal L-methionyl-L-lysyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein]


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Sus scrofa)


name: CTP(out) + UTP(in) => CTP(in) + UTP(out)


name: ganglioside GM2 (d18:1(4E)/18:0) + H2O = ganglioside GA2 (d18:1(4E)/18:0) + N-acetylneuraminate


name: Phosphorylation of USP8 by P-AKT (Homo sapiens)


name: PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Mus musculus)


name: Association of Cdh1 with the APC/C (Drosophila melanogaster)


name: PDCL binds G-protein beta and TRiC/CCT (Rattus norvegicus)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Xenopus tropicalis)


name: 5-methylcytosine + H(+) + H2O => NH4(+) + thymine


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Caenorhabditis elegans)


name: octadecanoyl-CoA + sphinganine = CoA + H(+) + N-(octadecanoyl)-sphinganine


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate <=> 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Caenorhabditis elegans)


name: CYP19A1 binds Aromatase inhibitors (Mus musculus)


name: H(+) + hnu + tetradecanoate = CO2 + tridecane


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Caenorhabditis elegans)


name: cytidine(3782) in 28S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(3782) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Rattus norvegicus)


name: (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone B


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Plasmodium falciparum)


name: Initial activation of proMMP9 by MMPs (Rattus norvegicus)


name: FBXL17 binds BACH1:MAFK (Drosophila melanogaster)


name: SLC22A1 transports Cipro into renal cell (Xenopus tropicalis)


name: RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Drosophila melanogaster)


name: (R)-pantoate + ATP => (R)-4-phosphopantoate + ADP + H(+)


name: Syndecans 2, (4) bind TGFB1 (Danio rerio)


name: PCho is dephosphorylated to Cho by PHOSPHO1 (Drosophila melanogaster)


name: N(omega),N(omega)-dimethyl-L-arginine + pyruvate => 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine


name: beta-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + ursodeoxycholate


name: 2-hydroxy-1-phenyl-1-propanone + NADP(+) = 1-phenyl-1,2-propanedione + H(+) + NADPH


name: GLB1 hydrolyses linker chain(2) (Homo sapiens)


name: H2O + N-acetylcadaverine = acetate + cadaverine


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)


name: (R)-mandelate + NAD(+) <=> H(+) + NADH + phenylglyoxylate


name: 7alpha-hydroxy-3,12-dioxo-5beta-cholanate + NADP(+) = dehydrocholate + H(+) + NADPH


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Schizosaccharomyces pombe)


name: S1P binds S1PR3 in response to E2 stimulation (Gallus gallus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Dictyostelium discoideum)


name: 2 H2O + 3 NADP(+) + NH4(+) = 5 H(+) + 3 NADPH + nitrite


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: A + H2O + prostaglandin H2 => (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2


name: Neurofascin interacts with syntenin-1 (Rattus norvegicus)


name: 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Dictyostelium discoideum)


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Gallus gallus)


name: NEMO binds polyubiquitinated IRAK1 (Canis familiaris)


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Danio rerio)


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Saccharomyces cerevisiae)


name: VAV exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate = 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: D-lysine + H2O + O2 <=> 6-amino-2-oxohexanoate + H2O2 + NH4(+)


name: A + protoaustinoid A => AH2 + protoaustinoid B


name: CAD hexamer transforms CAP to N-carb-L-Asp (Caenorhabditis elegans)


name: ATP + H2O + L-glutamine = AMP + 2 H(+) + N(5)-phospho-L-glutamine + phosphate


name: Syk activation leads to SLP-76 activation (Rattus norvegicus)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Saccharomyces cerevisiae)


name: (S)-beta-bisabolene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Haptoglobin binds Hemoglobin (Mus musculus)


name: (-)-(R)-19-hydroxytabersonine + acetyl-CoA => (-)-(R)-19-O-acetyltabersonine + CoA


name: ATP + glycine + holo-[peptidyl-carrier protein] = AMP + diphosphate + glycyl-[peptidyl-carrier protein]


name: Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex (Homo sapiens)


name: SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Saccharomyces cerevisiae)


name: GST dimers cleave AZA to 6MP (Xenopus tropicalis)


name: Activation of tandem pore domain in a weak inwardly rectifying  K+ channels (Rattus norvegicus)


name: 3-oxoadipate + NADP(+) = H(+) + maleylacetate + NADPH


name: 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Keratin tetramers bind to form unit length filaments (Danio rerio)


name: GGCT transforms gGluCys to OPRO (Xenopus tropicalis)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)


name: 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH => (6R)-5,6,7,8-tetrahydrobiopterin + 2 NADP(+)


name: Expression of ZSCAN4 in the embryo (Homo sapiens)


name: Initial activation of proMMP13 by MMP3 (Gallus gallus)


name: 2 H(+) + NADH + O2 + precorrin-3A = H2O + NAD(+) + precorrin-3B


name: MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)


name: an aldehyde + H2O2 => a primary alcohol + O2


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Schizosaccharomyces pombe)


name: Formation of collagen fibres (Sus scrofa)


name: meso-2,6-diaminoheptanedioate + NADP(+) = (S)-2,3,4,5-tetrahydrodipicolinate + 2 H(+) + NADPH + NH4(+)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Bos taurus)


name: SHP2 dephosphorylates Tyr 992 on EGFR (Drosophila melanogaster)


name: DAG stimulates protein kinase C-delta (Drosophila melanogaster)


name: ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] => ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate


name: 3-oxopropanoate + CoA + NADP(+) = acetyl-CoA + CO2 + NADPH


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Homo sapiens)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Gallus gallus)


name: acetyl-CoA + D-glutamate <=> CoA + H(+) + N-acetyl-D-glutamate


name: GBF1 stimulates nucleotide exchange on ARF4 (Schizosaccharomyces pombe)


name: 15-methylhexadecasphinganine 1-phosphate + ADP + H(+) => 15-methylhexadecasphinganine + ATP


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Homo sapiens)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + 2 H2O <=> 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + 2 chloride + 2 H(+)


name: Methylation of GMP-cap by RNA Methyltransferase (Bos taurus)


name: PTPRJ dephosphorylates active FLT3 (Canis familiaris)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine => 2-oxo-3-sulfanylpropanoate + L-kynurenine


name: NOX4, NOX5 reduce O2 to O2.- (Rattus norvegicus)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Mus musculus)


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Xenopus tropicalis)


name: adenosine(4) in tRNA(His) + S-adenosyl-L-methionine <=> 2'-O-methyladenosine(4) in tRNA(His) + H(+) + S-adenosyl-L-homocysteine


name: (S)-methylmalonyl-CoA + pyruvate => oxaloacetate + propanoyl-CoA


name: 8-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase] => 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Canis familiaris)


name: L-rhamnonate => 2-dehydro-3-deoxy-L-rhamnonate + H2O


name: RAC1 and CDC42 activate PAK3 (Drosophila melanogaster)


name: ethylamine + H2O + NAD(+) => acetaldehyde + H(+) + NADH + NH4(+)


name: Binding of ATP to P2X receptors (Canis familiaris)


name: GGT hydrolyses RCTR2 to RCTR3 (Homo sapiens)


name: GOPC promotes translocation of CFTR to lysosomes (Danio rerio)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: H2O + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a 1,2-diacyl-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)


name: butyl benzoate + CoA => benzoyl-CoA + butan-1-ol


name: ATP + L-homoserine <=> ADP + H(+) + O-phospho-L-homoserine


name: IL21 receptor JAK phosphorylation (Mus musculus)


name: chloride(out) + formate(in) => chloride(in) + formate(out)


name: heptan-2-one + hydrogen cyanide = (2S)-2-hydroxy-2-methylheptanenitrile


name: (+)-isoborneol + NAD(+) => (1S,4S)-camphor + H(+) + NADH


name: H(+) + N(1)-methylpseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-homocysteine => pseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-methionine


name: LDH tetramer reduces PYR to LACT (Mus musculus)


name: MBTPS2 (S2P) cleaves CREB3L3 (Sus scrofa)


name: 7,8-dihydroneopterin 3'-triphosphate <=> 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: ALK fusions phosphorylate IRS1 (Homo sapiens)


name: 6-chloro-D-tryptophan + FAD + 2 H2O => chloride + D-tryptophan + FADH2 + O2


name: arginine + H2O => ornithine + urea [ARG1] (Sus scrofa)


name: L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphoenolpyruvate => N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + pyruvate


name: DAG activation of TRPC channels (Homo sapiens)


name: H(+) + maleylacetate + NADPH => 3-oxoadipate + NADP(+)


name: A + beta-cyclopiazonate => AH2 + alpha-cyclopiazonate


name: Multiubiquitination of APC/C-associated Cdh1 (Rattus norvegicus)


name: fluoride + S-adenosyl-L-methionine => 5'-deoxy-5'-fluoroadenosine + L-methionine


name: PLA1A hydrolyses PS to 2-acyl LPS (Mus musculus)


name: Activation of TAK1 complex bound to activated TLR4 complex (Bos taurus)


name: MAPK12 phosphorylates PTPN3 (Bos taurus)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) (Sus scrofa)


name: Removal of remaining Flap (Rattus norvegicus)


name: H2O + NADP(+) + testololactone => androst-4-ene-3,17-dione + H(+) + NADPH + O2


name: Collagen type V degradation by MMP2,9,10 (Mus musculus)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Dictyostelium discoideum)


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Bos taurus)


name: (11R)-hydroxymethyl carlactonoate + CO2 + succinate => (11R)-methyl carlactonoate + 2-oxoglutarate + O2


name: 4-aminobutanoyl-[BtrI ACP] + ATP + L-glutamate => 4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + ADP + H(+) + phosphate


name: ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Rattus norvegicus)


name: ferric-vibriobactin transmembrane transporter activity


name: D-arabinose(out) + H(+)(out) = D-arabinose(in) + H(+)(in)


name: SLC26A4 transports I- from cytosol to extracellular region (Mus musculus)


name: Phosphorylation of LIMK-1 by PAK (Drosophila melanogaster)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Caenorhabditis elegans)


name: SUCLG1/G2 cleaves succinyl-CoA (Dictyostelium discoideum)


name: Caspase mediated cleavage of C-IAP1 (Sus scrofa)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-octanoylsphinganine + O2 = 2 Fe(III)-[cytochrome b5] + H2O + N-octanoyl-4-hydroxysphinganine


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Dictyostelium discoideum)


name: 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + rhizobitoxine => dihydrorhizobitoxine + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: holo-[(hydroxy)phthioceranic acid synthase] + octadecanoyl-AMP = AMP + H(+) + octadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: dimethylallyl diphosphate + L-tryptophan = 4-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: Src phosphorylate WASP,N-WASP (Homo sapiens)


name: AFG3L2 degrades mitochondrial matrix proteins (Caenorhabditis elegans)


name: hypotaurine + pyruvate = 2-sulfinoacetaldehyde + L-alanine


name: an aromatic (S)-hydroxynitrile => an aromatic aldehyde + hydrogen cyanide


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Drosophila melanogaster)


name: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)


name: Vamp2 associated secretory vesicle to plasma membrane transport (Homo sapiens)


name: 6-deoxyerythronolide B + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = erythronolide B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Caenorhabditis elegans)


name: Exchange of oxygen with sulfur in MoCo (Sus scrofa)


name: IL12B:IL23A translocates from ER lumen to extracellular space (Bos taurus)


name: MAPK1-dependent phosphorylation of MITF-M (Gallus gallus)


name: UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Rattus norvegicus)


name: 4-(hydroxy(methyl)phosphoryl)-2-oxobutanoate + L-glutamate => 2-oxoglutarate + L-phosphinothricin


name: OPS is added to the carrier sulfide (Mycobacterium tuberculosis)


name: MAPK4,6 translocate to nucleus (Sus scrofa)


name: CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate => acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)


name: Digestion of diacylglycerols by extracellular PTL:colipase (Homo sapiens)


name: Docking of Mature Histone mRNA complex:TAP at the NPC (Drosophila melanogaster)


name: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside


name: 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Caenorhabditis elegans)


name: baicalin + H2O <=> baicalein + D-glucuronate + H(+)


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Bos taurus)


name: 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Sus scrofa)


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Xenopus tropicalis)


name: a ganglioside GM3 + N-acetyl-beta-D-galactosamine => a ganglioside GM2 + H2O


name: DHODH:FMN oxidises (S)-DHO to orotate (Sus scrofa)


name: GFAP binds LAMP2a multimer (Homo sapiens)


name: dimethyl sulfide + H2O + menaquinone-8 => dimethyl sulfoxide + menaquinol-8


name: AH2 + O2 + protoaustinoid A = A + berkeleyone A + H2O


name: 3''-dehydroorientin <=> 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: H(+) + L-methionine = 3-(methylsulfanyl)propanamine + CO2


name: ALOX5 oxidises DHA to 7-HDHA (Mus musculus)


name: Integrin alpha2beta1 binds laminin-332 (Homo sapiens)


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Caenorhabditis elegans)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Saccharomyces cerevisiae)


name: WHSC1 binds DNA DSBs (Schizosaccharomyces pombe)


name: FarC-PTP4A2 binds RABGGTB (Dictyostelium discoideum)


name: H(+) + L-2-aminopentanoate + NADH + pyruvate => (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H2O + NAD(+)


name: (5-hydroxyindol-3-yl)acetaldehyde + H2O + NAD(+) => (5-hydroxyindol-3-yl)acetate + 2 H(+) + NADH


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Sus scrofa)


name: Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Sus scrofa)


name: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein]


name: cyclomaltodextrin + H2O = linear maltodextrin


name: 4 Fe(III)-[cytochrome cL] + H2O + methanol <=> 4 Fe(II)-[cytochrome cL] + formate + 5 H(+)


name: 2-MAG is transacylated to DAG by PNPLA2/3 (Homo sapiens)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] <=> 16alpha-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-hydroxy-L-kynurenine + pyruvate = H2O + L-alanine + xanthurenate


name: PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (13E)-labda-7,13-dien-15-yl diphosphate


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Drosophila melanogaster)


name: CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine (Dictyostelium discoideum)


name: a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+) = a very-long-chain 3-oxoacyl-CoA + H(+) + NADH


name: (6Z,9Z,12Z,15Z)-octadecatetraenoate + H2O <=> (10S)-hydroxy-(6Z,12Z,15Z)-octadecatrienoate


name: acetoacetate + coenzyme M + NADP(+) => 2-oxopropyl-coenzyme M + CO2 + NADPH


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Schizosaccharomyces pombe)


name: Bile salts dissociate from FABP6 (Mus musculus)


name: L1-FGFR cis-heterodimerization (Caenorhabditis elegans)


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Mus musculus)


name: 2,4-dinitrophenyl-S-glutathione(in) + ATP + H2O = 2,4-dinitrophenyl-S-glutathione(out) + ADP + H(+) + phosphate


name: SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Mus musculus)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Rattus norvegicus)


name: glutamate uptake by astrocytes (Danio rerio)


name: (R)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + salutaridine


name: Transhomodimerization of Nectin-like (Necl) proteins (Sus scrofa)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1,2-dihexadecanoyl-sn-glycerol + H(+) + phosphocholine


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Homo sapiens)


name: IRE1 dimer autophosphorylates (Caenorhabditis elegans)


name: Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) (Canis familiaris)


name: DKK promotes clathrin-dependent internalization of LRP6 (Sus scrofa)


name: DUS2:EPRS reduces uridine to dihydrouridine in tRNAs (Homo sapiens)


name: ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA (Danio rerio)


name: AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Sus scrofa)


name: Masitinib-resistant KIT mutants do not bind masitinib (Homo sapiens)


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Sus scrofa)


name: 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialurate + H(+) => FMNH2 + O2


name: n H(+)(out) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanine(out) = n H(+)(in) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanine(in)


name: RNF181 binds BCL10 and Ubiquitin:E2 (Rattus norvegicus)


name: Collagen type XXV ectomain shedding (Xenopus tropicalis)


name: 2,3-epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O <=> (3Z)-6-oxohex-3-enoyl-CoA + formate + H(+)


name: estrone 3-sulfate(out) + propanoate(in) => estrone 3-sulfate(in) + propanoate(out)


name: H2O + L-leucine + O2 <=> 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: Interleukin-5 is a homodimer (Sus scrofa)


name: MDC1 associates with gamma-H2AFX at nuclear foci (Drosophila melanogaster)


name: Rsu-1 interacts with Pinch1 (Gallus gallus)


name: Inner coat assembly and cargo binding (Drosophila melanogaster)


name: 11-hydroxysugiol + O2 + reduced [NADPH--hemoprotein reductase] = 11,20-dihydroxysugiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2'-deoxyuridine(in) + H(+)(in) <=> 2'-deoxyuridine(out) + H(+)(out)


name: ERK1/2 phosphorylates MSK1 (Mus musculus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Bos taurus)


name: RHOQ translocates to the Golgi-associated vesicle membranes (Drosophila melanogaster)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP


name: 2-oxoglutarate + L-aspartyl-[protein] + O2 <=> 3-hydroxy-L-aspartyl-[protein] + CO2 + succinate


name: (3,5-dihydroxyphenyl)acetyl-CoA + O2 = 2-(3,5-dihydroxyphenyl)-2-oxoacetate + CoA + H(+)


name: RBX1:CUL3 dissociates from forming autophagosome (Danio rerio)


name: FNTA:FNTB transfers FARN to GNGT1 (Rattus norvegicus)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP => 1D-myo-inositol hexakisphosphate + ADP + H(+)


name: Trimming of peptides in ER (Drosophila melanogaster)


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Homo sapiens)


name: (+)-isomalbrancheamide B + bromide + FAD + 2 H(+) => (+)-isomalbrancheamide D + FADH2


name: Binding of ERp57 (Drosophila melanogaster)


name: H2O + S-hexadecanoyl-L-cysteinyl-[protein] <=> H(+) + hexadecanoate + L-cysteinyl-[protein]


name: (2E,6E)-farnesyl diphosphate = (-)-alpha-gurjunene + diphosphate


name: 2 dimethylallyl diphosphate = (R)-lavandulyl diphosphate + diphosphate


name: Extracellular KSPG translocates to the lysosome for degradation (Canis familiaris)


name: 2-oxoglutarate + O2 + taurine => aminoacetaldehyde + CO2 + H(+) + succinate + sulfite


name: SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol (Canis familiaris)


name: all-trans-retinol + NAD(+) = all-trans-retinal + H(+) + NADH


name: a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: (R)-carnitine + Co(I)-[quaternary-amine-specific corrinoid protein] + H(+) => (3R)-4-(dimethylamino)-3-hydroxybutanoate + methyl-Co(III)-[quaternary-amine-specific corrinoid protein]


name: ADP + di-trans,octa-cis-undecaprenyl phosphate + H(+) => ATP + di-trans,octa-cis-undecaprenol


name: H(+) + heptan-2-one + NADH + NH4(+) => (2S)-heptan-2-amine + H2O + NAD(+)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Saccharomyces cerevisiae)


name: a 3-acylpyruvate + H2O <=> a carboxylate + H(+) + pyruvate


name: H(+) + N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine


name: D-mannose + GDP + H(+) => GDP-alpha-D-mannose + H2O


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: Phosphorylated GAB1 recruits PI3K to MET (Canis familiaris)


name: 4-methylpentanoyl-CoA + H2O = 4-methylpentanoate + CoA + H(+)


name: 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-dien-19-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-lactaldehyde + pyruvate => 2-dehydro-3-deoxy-L-rhamnonate


name: SCD5 desaturates ST-CoA to OLE-CoA (Canis familiaris)


name: RHOQ binds GOPC:CFTR (Rattus norvegicus)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Rattus norvegicus)


name: 7-dehydrodesmosterol + H(+) + NADPH = desmosterol + NADP(+)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + GTP => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + diphosphate + GMP


name: DAG is acylated to TAG by DGAT1/2 (Danio rerio)


name: 2-glutathionyl-2-methylbut-3-en-1-ol + NAD(+) => 2-glutathionyl-2-methylbut-3-enal + H(+) + NADH


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Danio rerio)


name: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate


name: RAC2:GTP binds NOX2 complex (Sus scrofa)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] <=> 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin]


name: L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Canis familiaris)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Gallus gallus)


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Homo sapiens)


name: Ragulator binds Rag dimers (Canis familiaris)


name: 4-methylpentanal + 2 H2O + 2 oxidized [adrenodoxin] + pregnenolone => (20R,22R)-20,22-dihydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: (S)-N-acetyl-1-phenylethylamine + H2O = (S)-1-phenylethylamine + acetate


name: EGFR non-clathrin mediated endocytosis (Mus musculus)


name: RAS GEFs promote RAS nucleotide exchange (Canis familiaris)


name: 2 hydrogencarbonate(out) + oxalate(in) => 2 hydrogencarbonate(in) + oxalate(out)


name: IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Bos taurus)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)


name: Caspase-mediated cleavage of PKC theta (Mus musculus)


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Canis familiaris)


name: 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine => [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: RHOG binds effectors at the plasma membrane (Gallus gallus)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + diphosphate => (2E)-geranyl diphosphate + 3-[(Z)-2-isocyanoethenyl]-1H-indole


name: (2R,3S)-tartrate + NAD(+) <=> dihydroxyfumarate + H(+) + NADH


name: Fe(II)-hydroxyheme i => Fe(II)-heme a + H2O


name: a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 10-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RHOA:GTP translocates to the ER membrane (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O <=> 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: ACSS3 ligates CoA to CH3COO- (Bos taurus)


name: Formation of CSL NCOR corepressor complex (Gallus gallus)


name: fumarate + L-arginine => 2-(N(omega)-L-arginino)succinate


name: PDE5A dimer binds PDE5A inhibitors (Drosophila melanogaster)


name: a fatty aldehyde + H2O + NAD(+) = a fatty acid + 2 H(+) + NADH


name: TP53 stimulates transcription of RRM2B gene (Homo sapiens)


name: EHMT1:EHMT2 dimethylates TP53 (Sus scrofa)


name: "prokaryotic ubiquitin-like protein ligase"


name: ORC6 translocates to the nucleus (Sus scrofa)


name: Formation of PRC2-EZH2 complex (Bos taurus)


name: brevianamide F + dimethylallyl diphosphate <=> deoxybrevianamide E + diphosphate


name: a ketone + H(+) + NADH => a secondary alcohol + NAD(+)


name: Protein 4.1 binds CASK (Xenopus tropicalis)


name: a 2-acylglycerol + H2O = a carboxylate + glycerol + H(+)


name: succinate-semialdehyde dehydrogenase (NADP+) activity


name: MDM2 ubiquitinates DYRK2 (Canis familiaris)


name: Cis-heterodimerization of L1 and Axonin-1 (Homo sapiens)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Canis familiaris)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Xenopus tropicalis)


name: Part of the ICD migrates to the nucleus (Gallus gallus)


name: 2 glutathione + L-cystine = glutathione disulfide + 2 L-cysteine


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Danio rerio)


name: Disassociation of CLIP from MHC II (Rattus norvegicus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + octadecanoate


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Gallus gallus)


name: alpha-secretase cleaves the p75NTR extracellular domain (Canis familiaris)


name: Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Caenorhabditis elegans)


name: Na(+)(out) + propanoate(out) <=> Na(+)(in) + propanoate(in)


name: PDK isozymes phosphorylate PDHC subunit E1 (Bos taurus)


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Bos taurus)


name: ATF2 acetylates histone H2B, H4 (Canis familiaris)


name: RAC1 and CDC42 activate PAK1 (Homo sapiens)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Caenorhabditis elegans)


name: STRA6 transports atROL from extracellular region to cytosol (Bos taurus)


name: (S)-nicotine + 2 Fe(III)-[cytochrome c] <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + N-methylmyosmine


name: malate dehydrogenase (decarboxylating) (NADP+) activity


name: SDHAF4 binds to FAD-SDHA (Schizosaccharomyces pombe)


name: Activated FGFR1 phosphorylates SHC1 (Homo sapiens)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Rattus norvegicus)


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Xenopus tropicalis)


name: Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Canis familiaris)


name: deamido-NAD(+)(in) + NAD(+)(out) = deamido-NAD(+)(out) + NAD(+)(in)


name: structural constituent of peritrophic membrane


name: H(+) + hexadecanoyl-CoA + NADPH => CoA + hexadecanal + NADP(+)


name: Disassociation and translocation of STATs to the nucleus (Canis familiaris)


name: ALDH2 transforms GTN to NO (Gallus gallus)


name: trypanothione-disulfide reductase (NADPH) activity


name: MTRR reduces cob(II)alamin to meCbl (Mus musculus)


name: PAK1 autophosphorylates (Drosophila melanogaster)


name: 2-aminomalonate semialdehyde + H(+) = aminoacetaldehyde + CO2


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Mus musculus)


name: p-STAT1:p-STAT4 translocates to the nucleus (Gallus gallus)


name: maltose + H2O => 2 D-glucose (sucrase-isomaltase) (Sus scrofa)


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Danio rerio)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 10,11-epoxy-(7Z,13Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol (Homo sapiens)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Rattus norvegicus)


name: (E)-4-coumaroyl-CoA + H(+) + NADPH => dihydro-4-coumaroyl-CoA + NADP(+)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Gallus gallus)


name: 2 [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 = [thyroglobulin]-dehydroalanine + [thyroglobulin]-L-thyroxine + 2 H2O


name: SGMS2 transfers phosphocholine onto ceramide (Homo sapiens)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Xenopus tropicalis)


name: Formation of the Spliceosomal B* complex (Homo sapiens)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine


name: Activated TLR5/TLR15 homodimer recruits MyD88 adaptor (Gallus gallus)


name: Release of GABA at the synapse (Canis familiaris)


name: Association of procollagen type VIII (Drosophila melanogaster)


name: a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine <=> an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine


name: Metallochaperone inserts 2Cu2+ into MT-CO2 (Sus scrofa)


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,24R-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine => H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide


name: dihydrochelirubine + O2 + reduced [NADPH--hemoprotein reductase] <=> 12-hydroxydihydrochelirubine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine <=> 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Danio rerio)


name: Exocytosis of tertiary granule membrane proteins (Rattus norvegicus)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Sus scrofa)


name: 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + CO2 + CoA => (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + H(+) + malonyl-CoA


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Rattus norvegicus)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + CoA => (13S,14R)-1,13-dihydroxy-N-methylcanadine + acetyl-CoA


name: Fibrillin-1 degradation by MMP14 (Bos taurus)


name: H(+) + 2 L-arginine + 3 NADH + 4 O2 <=> 4 H2O + 2 L-citrulline + 3 NAD(+) + 2 nitric oxide


name: (2Z,6E)-farnesyl diphosphate => (6R,7S)-2,2,6-trimethyl-10-methylenebicyclo[5.4.0]undec-1(11)-ene + diphosphate


name: 1-aci-nitro-2-(1H-indol-3-yl)ethane + glutathione = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H2O


name: AKT3 phosphorylates TBX3 (Drosophila melanogaster)


name: indolelactate dehydrogenase (NAD+) activity


name: SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane (Homo sapiens)


name: PLK3 phosphorylates TP53 (Xenopus tropicalis)


name: BCL2 binds BCL2 antagonists (Sus scrofa)


name: Parenchymal atROL translocates to HSCs (Canis familiaris)


name: 4-hydroxy-6-methylpretetramide + NADPH + O2 => 4-dedimethylamino-4-oxo-anhydrotetracycline + H2O + NADP(+)


name: A + all-trans-zeta-carotene <=> AH2 + all-trans-neurosporene


name: carbamate + H(+) + H2O => hydrogencarbonate + NH4(+)


name: alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose <=> alpha-D-mannosyl-(1->3)-alpha-D-galactosyl-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: acetyl-CoA + N-acetylneuraminate <=> CoA + N-acetyl-7-O-acetylneuraminate


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Mus musculus)


name: glycine + pyruvate => glyoxylate + L-alanine


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+) => 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-choline


name: Activated FGFR3 phosphorylates SHC1 (Homo sapiens)


name: Displacement of C2a/Bb by CR1 (Homo sapiens)


name: butanoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (2E)-butenoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: "butanoyl-CoA dehydrogenase complex (NAD(+), ferredoxin)"


name: IFNAR1:TYK2 binds TYK2 inhibitors (Bos taurus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: ULK1 Translocates to the mitochondria (Mus musculus)


name: Autocatalytic phosphorylation of FGFR1b (Canis familiaris)


name: 2-dehydro-D-glucose + L-phenylalanine => (2S)-3-phenyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O


name: glutathione(in) + urate(out) => glutathione(out) + urate(in)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Gallus gallus)


name: UCHL1, UCHL3 cleave ubiquitin adducts (Bos taurus)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Sus scrofa)


name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Homo sapiens)


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Caenorhabditis elegans)


name: CDO binds promyogenic cadherins (Homo sapiens)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Schizosaccharomyces pombe)


name: Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Bos taurus)


name: (7R,8S)-7,8-diammoniononanoate + CO2 = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + 2 H(+)


name: H(+) + N(2)-(ADP-D-ribosyl)-dGMP + nicotinamide => dGMP + NAD(+)


name: IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Sus scrofa)


name: glutamine + H2O => glutamate + NH4+ [GLS] (Sus scrofa)


name: Activation of IKK complex (Rattus norvegicus)


name: "Acting on ATP; involved in cellular and subcellular movement"


name: 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA = 1-butanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: a 3-oxo-5beta-steroid + NADP(+) => a 3-oxo-Delta(4)-steroid + H(+) + NADPH


name: mature RAS proteins translocate to plasma membrane (Caenorhabditis elegans)


name: MITF-M-dependent GMPR expression (Homo sapiens)


name: NPC1L1 binds ezetimibe (Caenorhabditis elegans)


name: a 3-vinylbacteriochlorophyllide d + H2O => a bacteriochlorophyllide d


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2 = 2-dehydro-D-glucose + an aliphatic amine + H2O2


name: "fructosyl amine oxidase (glucosone-forming)"


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Xenopus tropicalis)


name: (E)-cinnamate + UDP-alpha-D-glucose => 1-O-(trans-cinnamoyl)-beta-D-glucose + UDP


name: ATP + histamine + L-glutamate => ADP + H(+) + N(alpha)-gamma-L-glutamylhistamine + phosphate


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP-beta-L-colitose => alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP + H(+)


name: PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Canis familiaris)


name: Phosphorylation of p-KIT on Y900 by Src kinases (Mus musculus)


name: O2 + piceatannol <=> 3,4-dihydroxybenzaldehyde + 3,5-dihydroxybenzaldehyde


name: NEIL3 cleaves spiroiminodihydantoin (Bos taurus)


name: Co(I)-[glycine betaine-specific corrinoid protein] + H(+) + methyl-coenzyme M => coenzyme M + methyl-Co(III)-[glycine betaine-specific corrinoid protein]


name: S-adenosyl 3-(methylsulfanyl)propylamine + spermidine => H(+) + S-methyl-5'-thioadenosine + thermospermine


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-alpha-D-galactose <=> H(+) + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP


name: D-erythrose 4-phosphate + L-erythrulose = beta-D-fructose 6-phosphate + glycolaldehyde


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Plasmodium falciparum)


name: prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer (Sus scrofa)


name: 7-deoxyloganate + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + loganate + oxidized [NADPH--hemoprotein reductase]


name: AMP + diphosphate + hexanal + NADP(+) => ATP + H(+) + hexanoate + NADPH


name: ATP + CoA + eicosanoate => AMP + diphosphate + eicosanoyl-CoA


name: 2-methylpropanal + CoA + NAD(+) => 2-methylpropanoyl-CoA + H(+) + NADH


name: POU5F1 (OCT4), SOX2, NANOG, ZSCAN10, PRDM14, SMAD2, FOXP1-ES bind the POU5F1 (OCT4) promoter (Homo sapiens)


name: 5-(3-methylguanidino)-2-oxopentanoate + L-alanine => N(omega)-methyl-L-arginine + pyruvate


name: Association of procollagen type XX (Caenorhabditis elegans)


name: 5,6,7,8-tetrahydropteridine + NADP(+) => 6,7-dihydropteridine + H(+) + NADPH


name: 3-bromo-L-tyrosyl-[protein] + H2O => H(+) + hypobromite + L-tyrosyl-[protein]


name: AKT phosphorylates MKRN1 (Dictyostelium discoideum)


name: 3beta-hydroxy-5alpha-androstane-7,17-dione + H(+) + NADPH <=> 3beta,7beta-dihydroxy-5alpha-androstan-17-one + NADP(+)


name: H2O + triacetate lactone <=> H(+) + triacetate


name: Activated TAK1 leaves endosome membrane (Gallus gallus)


name: OCT1 transports organic cations into hepatic cells (Rattus norvegicus)


name: MAPK1 phosphorylates SOX10 (Xenopus tropicalis)


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Rattus norvegicus)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Xenopus tropicalis)


name: Vitronectin prevents C9 polymerization (Gallus gallus)


name: calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity


name: cAMP hydrolysis by Cam-PDE 1 (Homo sapiens)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + ethanolamine


name: HMGCR dimer reduces bHMG-CoA to MVA (Dictyostelium discoideum)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Rattus norvegicus)


name: corticosterone + H(+) + NADPH <=> 5beta-dihydrocorticosterone + NADP(+)


name: Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Xenopus tropicalis)


name: Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide <=> Ni(2+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Sus scrofa)


name: N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine <=> H(+) + N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP


name: L-cysteinyl-tRNA(Cys) + phosphate => H(+) + hydrogen sulfide + O-phospho-L-seryl-tRNA(Cys)


name: (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecenyl)-glycerol => 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: Activated FGFR2 binds SHC1 (Homo sapiens)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Mus musculus)


name: 2-hydroxyhexadecanoyl-CoA + sphinganine <=> CoA + H(+) + N-(2-hydroxyhexadecanoyl)-sphinganine


name: Binding of Pol kappa and REV1 complex to the lesion on the template DNA strand (Gallus gallus)


name: IDUA hydrolyses Heparan sulfate chain(6) (Xenopus tropicalis)


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Canis familiaris)


name: an N-acyl-D-aspartate + H2O <=> a carboxylate + D-aspartate


name: CBL binds and ubiquitinates phosphorylated Sprouty (Homo sapiens)


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] <=> atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: GNLY is transferred to the phagosome (Canis familiaris)


name: Defective TALDO1 does not transform SH7P, GA3P to Fru(6)P, E4P (Homo sapiens)


name: Caspase-mediated cleavage of claspin (Mus musculus)


name: H2O + tetradecanoyl-CoA = adenosine 3',5'-bisphosphate + 2 H(+) + tetradecanoyl-4'-phosphopantetheine


name: Activation of BAD by calcineurin (Sus scrofa)


name: (8Z,11Z,14Z)-heptadecatrienal + CO2 + H2O => (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + H(+)


name: aklavinone + H(+) + NADPH + O2 => epsilon-rhodomycinone + H2O + NADP(+)


name: a guanosine in RNA + S-adenosyl-L-methionine => an N(7)-methylguanosine in RNA + S-adenosyl-L-homocysteine


name: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone


name: 2 L-ascorbate + N-tetradecanoylglycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-tetradecanoyl-(2S)-hydroxyglycine


name: 3-oxohexadecanoyl-[ACP] + CO2 + CoA => H(+) + malonyl-[ACP] + tetradecanoyl-CoA


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Drosophila melanogaster)


name: Activation of MMP9 intermediate form by MMPs (Canis familiaris)


name: CHM binds RGGT (Saccharomyces cerevisiae)


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)


name: Myristoylation of tBID by NMT1 (Xenopus tropicalis)


name: 2 H(+) + hexadecanoyl-CoA + 2 malonyl-CoA <=> 4-hydroxy-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA


name: 6-hydroxytryprostatin B + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + tryprostatin A


name: orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2 (Gallus gallus)


name: KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Canis familiaris)


name: Mitochondrial BTD hydrolyses BCTN (Bos taurus)


name: H(+)(out) + sulfate(out) => H(+)(in) + sulfate(in)


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Saccharomyces cerevisiae)


name: H(+) + octadecanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-octadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: a uridine in mRNA + H(+) + NADPH => a 5,6-dihydrouridine in mRNA + NADP(+)


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Dictyostelium discoideum)


name: HRH2 binds hist (Drosophila melanogaster)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR3 (Drosophila melanogaster)


name: an N-acyl-sphingoid base + an oligoglycosyl-(1->4)-D-glucose => an oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: A1 and A3 receptors bind adenosine (Bos taurus)


name: H2O + L-xylono-1,4-lactone => H(+) + L-xylonate


name: Lsm1-7 Complex binds deadenylated mRNA (Canis familiaris)


name: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) <=> a 3-oxosteroid + CO2 + NADH


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: Cleavage of P-ERBB4jmA isoforms by ADAM17 (Homo sapiens)


name: SARS-CoV-2 nsp16 binds to U1 snRNA (Homo sapiens)


name: XPO1 (CRM1) binds to BACH1:Hemes (Rattus norvegicus)


name: 2-methylpropanoyl-CoA + H2O <=> 2-methylpropanoate + CoA + H(+)


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Gallus gallus)


name: CTP(out) + dGTP(in) => CTP(in) + dGTP(out)


name: CO binds to Cytochrome c oxidase (Canis familiaris)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Canis familiaris)


name: AMPK (complex) phosphorylates ULK1 (complex) (Xenopus tropicalis)


name: Degradation of ubiquitinated SKI/SKIL (Danio rerio)


name: Serine phosphorylation of STATs (Mus musculus)


name: NR1H2,3 binds the EEPD1 gene (Homo sapiens)


name: (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + H(+) + phosphate => (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate


name: Integrin alpha5beta1 binds FN1 dimer (Mus musculus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)


name: pteridine-2,4,6,7-tetrol => H(+) + xanthine-8-carboxylate


name: oxidoreductase activity, acting on a heme group of donors


name: Phosphorylated MAPKs phosphorylate ATF-2 (Saccharomyces cerevisiae)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Rattus norvegicus)


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Xenopus tropicalis)


name: diphosphate + L-glutamyl-5'-AMP => ATP + H(+) + L-glutamate


name: (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b5] + H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + squalene


name: (2E)-geraniol + ATP => (2E)-geranyl phosphate + ADP + H(+)


name: (13Z)-3-oxodocosenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(13Z)-docosenoyl-CoA + NADP(+)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Canis familiaris)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH => (R)-mevalonate + CoA + 2 NAD(+)


name: SST gene expression is stimulated by MECP2 and CREB1 (Homo sapiens)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Mus musculus)


name: Formation of fatty acid synthase (FAS) dimer (Dictyostelium discoideum)


name: a ganglioside GQ1b (d18:1(4E)) + H2O => a ganglioside GT1b (d18:1(4E)) + N-acetylneuraminate


name: (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+) => D-ribulose 5-phosphate


name: H(+) + heptanoyl-CoA + malonyl-[ACP] <=> 3-oxononanoyl-[ACP] + CO2 + CoA


name: Potassium voltage-gated channels close in reponse to PKA (Danio rerio)


name: USP19 binds HIF1A,BIRC2,BIRC3 (Homo sapiens)


name: Inactive G alpha (i) reassociates with G beta:gamma (Caenorhabditis elegans)


name: (4R,8Z)-4-hydroxysphing-8-enine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Rattus norvegicus)


name: MRRF binds 55S ribosome:mRNA:tRNA (Canis familiaris)


name: 5alpha-androstan-3,17-dione + H(+) + NADH => androsterone + NAD(+)


name: 2-demethylmenaquinol-6 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-hexaprenyl diphosphate + H(+)


name: RNASEs bind bacterial phospholipids (Mus musculus)


name: TOPORS SUMOylates SIN3A with SUMO1 (Xenopus tropicalis)


name: 6-acetamido-2-oxohexanoate + L-glutamate => 2-oxoglutarate + N(6)-acetyl-L-lysine


name: p-4Y-SIRPA:CD47 binds PTK2B (Mus musculus)


name: FAS-mediated dimerization of procaspase-8 (Mus musculus)


name: 2xTNFR2 binds TNFA trimer:TNFR2 (Rattus norvegicus)


name: S-adenosyl-L-methionine + uridine(2634) in 25S rRNA <=> H(+) + N(3)-methyluridine(2634) in 25S rRNA + S-adenosyl-L-homocysteine


name: A + O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine <=> AH2 + alstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine


name: bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE (Dictyostelium discoideum)


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Homo sapiens)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Homo sapiens)


name: FGFR2c binds to FGF (Drosophila melanogaster)


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Gallus gallus)


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Caenorhabditis elegans)


name: dUMP + 2 H(+) + 2 phosphate => dUTP + 2 H2O


name: PREDL:ALB dissociates (Canis familiaris)


name: 7-dehydrocholesterol + hnu = previtamin D3


name: NAD(+) + resolvin D1 = 17-oxoresolvin D1 + H(+) + NADH


name: a dolichyl phosphate + H2O => di-trans,poly-cis-dolichol + phosphate


name: H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol = a fatty acid + H(+) + long chain acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: L-aspartate(in) + L-tyrosine(out) = L-aspartate(out) + L-tyrosine(in)


name: Activation of TAK1 complex bound to activated TLR4 complex (Gallus gallus)


name: (2S)-hesperetin 7-O-beta-D-glucoside + H(+) + UDP => (2S)-hesperetin + UDP-alpha-D-glucose


name: sequestered tissue factor -> tissue factor (Rattus norvegicus)


name: 2 A + all-trans-zeta-carotene => 2 AH2 + all-trans-lycopene


name: MSH2:MSH6 exchanges ADP for ATP (Gallus gallus)


name: arginine + H2O => ornithine + urea [ARG2] (Plasmodium falciparum)


name: Binding of TFIIE to the growing preinitiation complex (Saccharomyces cerevisiae)


name: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal


name: 5-pyridoxolactone + H(+) + NADH => isopyridoxal + NAD(+)


name: a 5'-end phospho-ribonucleoside in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP => a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O


name: 2-methylpropanoate + ATP + CoA = 2-methylpropanoyl-CoA + AMP + diphosphate


name: 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O = 2-nonadioyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: carbonyl sulfide + H2O <=> CO2 + H(+) + hydrogen sulfide


name: Complement factor I binds to MCP, CR1:C4b, C3b (Sus scrofa)


name: Hh-Npp binds CDON and PTCH (Canis familiaris)


name: TRIKA2 binds K63polyUb-TRAF6 oligomer (Sus scrofa)


name: gamma-secretase cleaves EPHB2 (Xenopus tropicalis)


name: FH tetramer hydrates fumarate to L-malate (Rattus norvegicus)


name: 9-cis-4-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase] = 9-cis-4-oxoretinoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Caspase-mediated cleavage of Z0-2 (Rattus norvegicus)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Xenopus tropicalis)


name: H2O + L-glutamate 5-semialdehyde + NADP(+) = 2 H(+) + L-glutamate + NADPH


name: Recruitment of Plk1 to centrosomes (Sus scrofa)


name: ATP + holo-[peptidyl-carrier protein] + L-glutamate => AMP + diphosphate + L-glutamyl-[peptidyl-carrier protein]


name: TLR9 processing at neutral pH (Homo sapiens)


name: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H2O => 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate


name: H(+)(in) + L-glutamate(in) <=> H(+)(out) + L-glutamate(out)


name: 2 Na(+)(out) + tauronorcholate(out) <=> 2 Na(+)(in) + tauronorcholate(in)


name: PTK2 autophosphorylates downstream of EGFR (Homo sapiens)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Bos taurus)


name: AJUBA facilitates AURKA autophosphorylation (Mus musculus)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Xenopus tropicalis)


name: BRAP binds KSR1:MARK3 (Caenorhabditis elegans)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Danio rerio)


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Mus musculus)


name: IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Xenopus tropicalis)


name: D-proline(out) + H(+)(out) = D-proline(in) + H(+)(in)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + NAD(+) => androst-4-ene-3,11,17-trione + H(+) + NADH


name: 3-bromo-4-hydroxybenzoate + 2 H2O + NADP(+) => 4-hydroxybenzoate + bromide + 2 H(+) + NADPH + O2


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Sus scrofa)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O => (S)-2-amino-6-oxoheptanedioate


name: NTPDase7 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: 2-oxoglutarate + H(+) + isochorismate <=> 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2


name: a ganglioside GD1b (d18:1(4E)) + H(+) + UDP => a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Homo sapiens)


name: 1-O-(trans-4-coumaroyl)-beta-D-glucose + cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) betaine = beta-D-glucose + cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside] + H(+)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Xenopus tropicalis)


name: SPHK1 phosphorylates sphingosine in response to E2 stimulation (Homo sapiens)


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Sus scrofa)


name: 2 Fe(III)-[cytochrome c] + S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate = 2 Fe(II)-[cytochrome c] + 2 H(+) + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein]


name: IL10 dimer binds IL10RA:JAK1 (Danio rerio)


name: Association of GABA B receptor with G protein beta-gamma subunits (Sus scrofa)


name: ATP + formate <=> ADP + formyl phosphate


name: Activation of EPACs by cAMP (Drosophila melanogaster)


name: 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine => 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+)


name: D-glucose + H(+) + sulfate => D-glucose 6-sulfate + H2O


name: Clusterin binds C5b-C7, C8, C9 (Canis familiaris)


name: cytochrome-b5 reductase activity, acting on NAD(P)H


name: Ubiquitinated IkB is degraded (Canis familiaris)


name: holothin + pseudomonoyl-CoA C = CoA + pseudomonic acid C--holothin


name: 2 NADP(+) + tetrahydrocurcumin <=> curcumin + 2 H(+) + 2 NADPH


name: GALK1 phosphorylates Gal to Gal1P (Sus scrofa)


name: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH => 2,6-dioxo-6-phenylhexanoate + NADP(+)


name: ATP + lipid A disaccharide (E. coli) => ADP + H(+) + lipid IVA (E. coli)


name: PTPN3 dephosphorylates EPS15 (Sus scrofa)


name: RHOB binds effectors on endosomes (Drosophila melanogaster)


name: 5-dehydro-D-gluconate + H(+) + NADH => D-gluconate + NAD(+)


name: arbutin 6-phosphate + H2O => beta-D-glucose 6-phosphate + hydroquinone


name: 2 AH2 + all-trans-beta-carotene + 2 O2 => 2 A + echinenone + 3 H2O


name: [small archaeal modifier protein]-C-terminal Gly-Gly + ATP + H(+) <=> [small archaeal modifier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: Exocytosis of azurophil granule membrane proteins (Saccharomyces cerevisiae)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Sus scrofa)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Rattus norvegicus)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Xenopus tropicalis)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NMRK2 phosphorylates NR to yield NMN (Danio rerio)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Canis familiaris)


name: griseophenone D + S-adenosyl-L-methionine <=> griseophenone C + S-adenosyl-L-homocysteine


name: Synthesis of ENV polyprotein (Homo sapiens)


name: Hydrolysis of PIP2 by PLCG (Xenopus tropicalis)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Bos taurus)


name: CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD (Homo sapiens)


name: CYP3A4 oxidizes PREDN,PREDL (Danio rerio)


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Gallus gallus)


name: Activated FGFR2 binds PLCG1 (Danio rerio)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] = 1,9-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADP-D-glycero-beta-D-manno-heptose + L-seryl-[protein] <=> ADP + H(+) + O-(D-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein]


name: GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress (Rattus norvegicus)


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde = H(+) + H2O + quinolinate


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+) + octadecanoate


name: TP53 binds the IGFBP3 gene (Homo sapiens)


name: Ubiquitinated IkB is degraded (Danio rerio)


name: ATP + L-seryl-[I-kappa-B protein] <=> ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein]


name: PIAS1,3 SUMOylate MBD1 with SUMO1 (Homo sapiens)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+) <=> (6R)-5,10-methenyltetrahydrofolate + NADH


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)


name: CDO binds promyogenic cadherins (Rattus norvegicus)


name: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 => A + a 3-demethylubiquinol + H2O


name: Separation of sister chromatids (Rattus norvegicus)


name: EDNRA, EDNRB bind non-selective ERAs (Danio rerio)


name: USP17 deubiquitinates SUDS3 (Bos taurus)


name: a ubiquinol + Na(+)(out) + NAD(+) => a ubiquinone + H(+) + Na(+)(in) + NADH


name: AH2 + all-trans-beta-carotene + O2 <=> 4-hydroxy-all-trans-beta-carotene + A + H2O


name: guanyl-nucleotide exchange factor adaptor activity


name: H2O + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) <=> acetate + alpha-D-glucosaminyl-[heparan sulfate](n)


name: a (2E)-2-fatty-enoyl-AMP + holo-[ACP] => a (2E)-enoyl-[ACP] + AMP + H(+)


name: 5alpha-pregnane-3,20-dione + H(+) + NADH => 5alpha-pregnan-20beta-ol-3-one + NAD(+)


name: a ganglioside GM3 + H2O = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-acetylneuraminate


name: coenzyme M + methyl-Co(III)-[methanol-specific corrinoid protein] = Co(I)-[methanol-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: "[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase"


name: DCAKD phosphorylates DP-CoA (Homo sapiens)


name: (3R)-3-hydroxy-L-arginyl-[ribosomal protein eS6] + CO2 + succinate => 2-oxoglutarate + L-arginyl-[ribosomal protein eS6] + O2


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 9-hydroperoxy-(5Z,7E,11Z,14Z)-eicosatetraenoate


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Drosophila melanogaster)


name: CDP-alpha-D-abequose + NADP(+) <=> CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H(+) + NADPH


name: 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin] => glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine


name: pyruvate + taurine => L-alanine + sulfoacetaldehyde


name: NOTCH1 PEST domain mutants bind MYC promoter (Homo sapiens)


name: Joining of adjacent Okazaki fragments (Saccharomyces cerevisiae)


name: SUMOylation of TOP1 with SUMO1 (Danio rerio)


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Gallus gallus)


name: methylamine dehydrogenase (amicyanin) activity


name: 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + CMP + H(+) => CMP-N-acetyl-beta-neuraminate + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein]


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin] = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: cis-(homo)2aconitate + H2O => (2R,3S)-iso(homo)2citrate


name: 3-guanidinopropanoate + H2O => beta-alanine + urea


name: glutarate(out) + urate(in) <=> glutarate(in) + urate(out)


name: H(+) + hexanal + NADH => hexan-1-ol + NAD(+)


name: Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2 (Homo sapiens)


name: ADH5 oxidises S-HMGSH to S-FGSH (Canis familiaris)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Sus scrofa)


name: AMP + diphosphate => 5-phospho-alpha-D-ribose 1-diphosphate + adenine


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Caenorhabditis elegans)


name: [protein]-disulfide + 2 glutathione => [protein]-dithiol + glutathione disulfide


name: biliverdin IXalpha + CO + Fe(2+) + 3 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] => 8 H(+) + heme b + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin]


name: Cipro:ALB dissociates (Canis familiaris)


name: dibenzothiophene 5,5-dioxide + FMNH2 + NADH + O2 = 2'-hydroxybiphenyl-2-sulfinate + FMN + H(+) + H2O + NAD(+)


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Drosophila melanogaster)


name: acetyl-CoA + dodecanoyl-CoA <=> 3-oxotetradecanoyl-CoA + CoA


name: H2O + indole-3-acetamide <=> (indol-3-yl)acetate + NH4(+)


name: PITPNM1,2,3 exchange PI for PA (Plasmodium falciparum)


name: L-arginine + L-cysteinyl-[NO transferase protein] + NADPH + 2 O2 = 2 H2O + L-citrulline + NADP(+) + S-nitroso-L-cysteinyl-[NO transferase protein]


name: (3R)-3-amino-3-phenylpropanoyl-CoA + baccatin III = 3'-N-debenzoyl-2'-deoxytaxol + CoA


name: Fusion of early-endosome derived vesicles at the TGN (Rattus norvegicus)


name: aromatic (S)-hydroxynitrile lyase activity


name: Association of Cks1 with SCF(Skp2) complex (Gallus gallus)


name: fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Mus musculus)


name: Translocation of Ezrin to plasma membrane (Bos taurus)


name: a 3-oxosteroid + CO2 + NADH => a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+)


name: 5-N(alpha)-glycyl-dTMP in DNA + A + H2O => 5-aminomethyl-dUMP in DNA + AH2 + glyoxylate


name: SLC7A10-mediated uptake of small neutral amino acids (Homo sapiens)


name: HNF1B binds the IRX1 gene (Homo sapiens)


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Mus musculus)


name: Melanocortin receptors bind melanocortins (Xenopus tropicalis)


name: 32-hydroxy-24,25-dihydrolanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H(+) + H2O <=> NH4(+) + pre-mycofactocin


name: Integrin alpha5beta1 binds FN1 dimer (Caenorhabditis elegans)


name: Metallochaperone inserts 2Cu2+ into MT-CO2 (Drosophila melanogaster)


name: PPA2A dephosphorylates SPRY2 (Mus musculus)


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Homo sapiens)


name: H2O + herqueinone + NADP(+) => deoxyherqueinone + H(+) + NADPH + O2


name: LDLR:LDL complex => LDLR + LDL (Rattus norvegicus)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Canis familiaris)


name: a dolichyl beta-D-mannosyl phosphate + H2O => a dolichyl phosphate + D-mannose + H(+)


name: ADP + H(+) + methylmalonyl-CoA + phosphate => ATP + hydrogencarbonate + propanoyl-CoA


name: 2-(2-methylsulfanyl)ethylmaleate + H2O => 3-(2-methylsulfanyl)ethylmalate


name: p-PRKRA dimer binds PKR (Drosophila melanogaster)


name: myo-inositol + S-adenosyl-L-methionine => 1D-1-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: NKG2D homodimer interacting with ligands (Mus musculus)


name: CoA + octyl acetate => acetyl-CoA + octan-1-ol


name: ATP + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide => 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + diphosphate


name: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate


name: acetyl-CoA + L-methionine sulfone => CoA + H(+) + N-acetyl-L-methionine sulfone


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine <=> 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: Pol II elongation complex moves on the template as transcript elongates (Caenorhabditis elegans)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O <=> a 5'-end phospho-guanosine in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite => 4-nitro-6-oxohepta-2,4-dienedioate


name: 2-demethylmenaquinol-9 + S-adenosyl-L-methionine <=> H(+) + menaquinol-9 + S-adenosyl-L-homocysteine


name: 3-oxohexacosanoyl-CoA + CoA => acetyl-CoA + tetracosanoyl-CoA


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Canis familiaris)


name: Connexin 36 mediated neuronal gap junction communication (Danio rerio)


name: 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + silphinene-15-oate => 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + silphinene


name: all-trans-retinol--[retinol-binding protein] + NAD(+) => all-trans-retinal--[retinol-binding protein] + H(+) + NADH


name: 3,4-dihydroxyphenylacetate + chloride + NAD(+) => 4-chlorophenylacetate + NADH + O2


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Sus scrofa)


name: n adenosine 3',5'-bisphosphate + chondroitin 4',6'-bissulfate + n H(+) => n 3'-phosphoadenylyl sulfate + chondroitin 4'-sulfate


name: an alpha-Kdo-(2->6)-lipid IVA + CMP + H(+) => a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> (2E,6E,10E)-geranylgeraniol + diphosphate


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Caenorhabditis elegans)


name: TRAFs bind RANK:RANKL (Rattus norvegicus)


name: 3,7-dimethylocta-2,6-dienoate + 2 H(+) + NADPH => citral + H2O + NADP(+)


name: a 4,5-didehydrojasmonate + H(+) + NADPH <=> a jasmonate + NADP(+)


name: ATP + H2O + taurocholate(in) <=> ADP + H(+) + phosphate + taurocholate(out)


name: AH2 + NH4(+) + O2 <=> A + H(+) + H2O + hydroxylamine


name: 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine => guanosine(18) in tRNA + S-adenosyl-L-methionine


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Canis familiaris)


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Xenopus tropicalis)


name: 3-chloro-4-methylcatechol + NAD(+) + nitrite => 2-chloro-4-nitrotoluene + NADH + O2


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2 = (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate


name: H2O + lovastatin = H(+) + lovastatin carboxylate


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Homo sapiens)


name: RNASEs bind bacterial phospholipids (Rattus norvegicus)


name: H(+) + NADH + phenanthrene-3,4-diol => (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Rattus norvegicus)


name: GPRC6A can bind L-alpha amino acids and calcium (Rattus norvegicus)


name: Disassembly of SR-BI-bound spherical HDL (Bos taurus)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Bos taurus)


name: Activated FGFR3 phosphorylates PLCG1 (Drosophila melanogaster)


name: arsenite + H2O + 2 oxidized [azurin] <=> arsenate + 3 H(+) + 2 reduced [azurin]


name: Caspase-mediated cleavage of alpha adducin (Sus scrofa)


name: Complement factor I binds to extracellular Factor H:C3b (Homo sapiens)


name: 2 L-dopa + O2 = 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+)


name: LC3:ATG7 dimer binds ATG3 (Canis familiaris)


name: Activated protein C cleaves factor VIIIa (Bos taurus)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Drosophila melanogaster)


name: H2O + L-saccharopine + NAD(+) = (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADH


name: "saccharopine dehydrogenase (NAD(+), L-glutamate-forming)"


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Danio rerio)


name: Disassociation of PLC-gamma1 from LAT (Bos taurus)


name: ALDH3A2-1 oxidises HD2NAL to PALM (Sus scrofa)


name: (S)-2-amino-6-oxohexanoate + H2O + NADP(+) => 2 H(+) + L-2-aminoadipate + NADPH


name: 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O <=> a fatty acid + acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+)


name: 12 H(+) + 6 malonyl-CoA + NADH + 5 NADPH => (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + 6 CO2 + 6 CoA + 4 H2O + NAD(+) + 5 NADP(+)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Drosophila melanogaster)


name: folic acid transmembrane transporter activity


name: ATP + hydrogencarbonate + tetracosanoyl-CoA <=> 2-carboxytetracosanoyl-CoA + ADP + H(+) + phosphate


name: MIOX oxidises Ins to GlcA (Mus musculus)


name: Formation of TSC1:TSC2 complex (Xenopus tropicalis)


name: L-lyxonate => 2-dehydro-3-deoxy-L-arabinonate + H2O


name: (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Canis familiaris)


name: 8,12-diethyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine <=> 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: UGCG transfers glucose to ceramide (Danio rerio)


name: Metabotropic glutamate receptors bind glutamate (Caenorhabditis elegans)


name: USP13 and OTUD3 deubiquitinate PTEN (Dictyostelium discoideum)


name: a 4-H-anthocyanidin with a 3-hydroxy group + CO2 + 2 H2O + succinate => 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2


name: ADP + guanine(in) + H(+) + phosphate => ATP + guanine(out) + H2O


name: ALDH3B1 oxidises HXAL to PALM (Danio rerio)


name: H2O + NAD(+) + perillyl aldehyde => 2 H(+) + NADH + perillate


name: 5-deoxy-alpha-D-ribose 1-phosphate = 5-deoxy-D-ribulose 1-phosphate


name: PLCG2 translocates from cytosol to plasma membrane (Bos taurus)


name: Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Xenopus tropicalis)


name: DIAPH1 binds RHOA:GTP (Drosophila melanogaster)


name: phosphate + pyridoxamine <=> H2O + pyridoxamine 5'-phosphate


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Mus musculus)


name: D-arabinose(out) + H(+)(out) <=> D-arabinose(in) + H(+)(in)


name: (13Z)-docosenoyl-CoA + sphing-4-enine <=> CoA + H(+) + N-(13Z-docosenoyl)-sphing-4-enine


name: ATP + CoA + deoxycholate => AMP + deoxycholoyl-CoA + diphosphate


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Drosophila melanogaster)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Rattus norvegicus)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Mus musculus)


name: 5-HT2 receptor can bind serotonin (Bos taurus)


name: (E)-caffeoylpyruvate + CO2 + hnu => 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Plasmodium falciparum)


name: 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine => L-histidine + 3 S-adenosyl-L-methionine


name: SHP-1 and SHP-2 bind pBTLA (Canis familiaris)


name: H(+) + NADH + O2 + quinolin-2-ol => H2O + NAD(+) + quinoline-2,8-diol


name: MBTPS1 (S1P) cleaves CREB3L3 (Sus scrofa)


name: (E)-cinnamate + UDP-alpha-D-glucose <=> 1-O-(trans-cinnamoyl)-beta-D-glucose + UDP


name: 2'-O-methylguanosine(2270) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine => guanosine(2270) in 21S rRNA + S-adenosyl-L-methionine


name: a medium-chain 3-oxoacyl-CoA + H(+) + NADH => a medium-chain (3R)-hydroxyacyl-CoA + NAD(+)


name: Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS (Homo sapiens)


name: GAB1 phosphorylation by EGFR kinase (Danio rerio)


name: H(+)(out) + thymidine(out) => H(+)(in) + thymidine(in)


name: S-adenosyl-L-methionine + xanthotoxol <=> H(+) + S-adenosyl-L-homocysteine + xanthotoxin


name: 2-aminoprop-2-enoate + chloride + H(+) => 3-chloro-D-alanine


name: Translocation of STAT1 dimer to nucleus (Bos taurus)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Drosophila melanogaster)


name: EDNRA binds selective ERAs (Gallus gallus)


name: N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity


name: p-Y705,S727-STAT3 dimerizes (Bos taurus)


name: a neolactoside IV(3)-alpha-NeuGc-nLc4Cer + UDP-N-acetyl-alpha-D-galactosamine = a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer + H(+) + UDP


name: 19-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin] => 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: Fibronectin degradation by ADAM8 (Homo sapiens)


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Homo sapiens)


name: echinenone + H2O => 4,4-dihydroxy-all-trans-beta-carotene


name: loading of Serotonin in synaptic vesicles (Drosophila melanogaster)


name: GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Rattus norvegicus)


name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA (Mus musculus)


name: (S)-acetoin + H(+) + NADH => (S,S)-butane-2,3-diol + NAD(+)


name: CoA + GTP + succinate <=> GDP + phosphate + succinyl-CoA


name: 5 H(+) + 2 O2 + protochlorophyllide a + 4 reduced [2Fe-2S]-[ferredoxin] <=> 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + protochlorophyllide b


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Homo sapiens)


name: H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O


name: ATP + L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphate = AMP + diphosphate + H(+) + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase]


name: Two FPP molecules dimerize to form presqualene diphosphate (Bos taurus)


name: GRK2 sequesters activated Gq (Mus musculus)


name: DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Sus scrofa)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Sus scrofa)


name: a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)


name: beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-beta-L-fucose => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: DNA-PKcs autophosphorylates (Rattus norvegicus)


name: Formation of RAD50:MRE11 complex (Caenorhabditis elegans)


name: ent-copalyl diphosphate + H2O => (-)-ent-copalol + diphosphate


name: ITGA4:ITGB1 binds natalizumab (Gallus gallus)


name: PITPNM1,2,3 exchange PI for PA (Canis familiaris)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Rattus norvegicus)


name: H2O + N-(4-carboxy-4-oxobutanoyl)-L-ethylglycylglycine <=> 2-oxoglutarate + N-(2-aminobutanoyl)glycine


name: Formation of lysyl-pyrrole cross-links (Gallus gallus)


name: (2E)-geranyl diphosphate + H2O = 1,8-cineole + diphosphate


name: IRF1 binds the promoters of Interferon alpha and beta (Homo sapiens)


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Caenorhabditis elegans)


name: G-protein alpha subunit is inactivated (Schizosaccharomyces pombe)


name: 17alpha-hydroxywithaferin A + UDP-alpha-D-glucose => 17alpha-sitoindoside IX + H(+) + UDP


name: acetone + H(+) + NADH + O2 = H2O + hydroxyacetone + NAD(+)


name: ALDH3B2 oxidises HXAL to PALM (Drosophila melanogaster)


name: 10-hydroxyoctadecanoate => (10E)-octadecenoate + H2O


name: p-T774-PKN1 phosphorylates CDC25C (Caenorhabditis elegans)


name: (E)-4-coumaroyl-CoA + 5-hydroxyanthranilate = avenanthramide A + CoA


name: BRCA1 binds phosphorylated RBBP8 (Rattus norvegicus)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Canis familiaris)


name: Translocation of PLC-gamma1 to PIP2 (Sus scrofa)


name: 3,4,5-trihydroxybenzoate + H(+) => 1,2,3-trihydroxybenzene + CO2


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP => an N-acylsphing-4-enine + UDP-alpha-D-galactose


name: AMP + diphosphate + omega-dicarboxyl-CoA => a dicarboxylate + ATP + CoA


name: carminate + O2 = 3'-dehydrocarminate + H2O2


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Drosophila melanogaster)


name: H2O + mycophenolyl-CoA <=> CoA + H(+) + mycophenolate


name: USP17 deubiquitinates SUDS3 (Drosophila melanogaster)


name: chloride(out) + D-tryptophan(out) + 2 Na(+)(out) => chloride(in) + D-tryptophan(in) + 2 Na(+)(in)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Rattus norvegicus)


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Xenopus tropicalis)


name: 1-octadecanoyl-2-nonanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + nonanoate


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Homo sapiens)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Rattus norvegicus)


name: anthranilate + 3 H(+) + NADH + O2 <=> catechol + CO2 + NAD(+) + NH4(+)


name: Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA (Canis familiaris)


name: 1,2-dichloroethane + H2O <=> 2-chloroethanol + chloride + H(+)


name: 1-octanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA


name: RNA polymerase II general transcription initiation factor binding


name: HCMV TRS1 binds PKR dimer (Homo sapiens)


name: alpha-maltopentaose + beta-maltose => alpha-maltohexaose + beta-D-glucose


name: Gq alpha activates Phospholipase C beta (Homo sapiens)


name: 2'-deoxyguanosine + IMP => dGMP + inosine


name: 27-hydroxysterol binds ESR1, ESR2 (Xenopus tropicalis)


name: TGFBR3(1-783) binds to TGFB1,TGFB2 (Canis familiaris)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Canis familiaris)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Sus scrofa)


name: ATP + cadaverine + L-glutamate => ADP + gamma-L-glutamylcadaverine + H(+) + phosphate


name: formaldehyde + H2O + NAD(+) + sulfite => methanesulfonate + NADH + O2


name: D-glyceraldehyde 3-phosphate + H(+) + pyruvate => 1-deoxy-D-xylulose 5-phosphate + CO2


name: Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Sus scrofa)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Canis familiaris)


name: CES1 hydrolyses sacubitril to sacubitrilat (Dictyostelium discoideum)


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Mus musculus)


name: D-glucose 6-phosphate + UDP-alpha-D-glucose <=> alpha,alpha-trehalose 6-phosphate + H(+) + UDP


name: (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H2O <=> 6-methyl-3,7-dioxodecanedioyl-CoA


name: (+)-malbrancheamide B + chloride + FAD + 2 H(+) <=> (+)-malbrancheamide + FADH2


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Sus scrofa)


name: 13-dihydrocarminomycin + H(+) + NADPH + O2 => carminomycin + 2 H2O + NADP(+)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Canis familiaris)


name: (2R)-2-hydroxy-2-methylbutanenitrile => butan-2-one + hydrogen cyanide


name: AFG3L2 binds mitochondrial matrix proteins (Xenopus tropicalis)


name: Cyclisation of GTP to precursor Z (Caenorhabditis elegans)


name: AKR1C3 reduces atRAL to atROL (Bos taurus)


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Rattus norvegicus)


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Xenopus tropicalis)


name: H(+) + NADPH + O2 + phenylacetyl-CoA => 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+)


name: 2-oxoglutarate + 3-methylbutanoyl-CoA + O2 => 2-hydroxy-3-methylbutanoyl-CoA + CO2 + succinate


name: structural constituent of pupal chitin-based cuticle


name: 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+) => a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: USP25 deubiquitinates DDX58 (Caenorhabditis elegans)


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Gallus gallus)


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: PA is converted to CDP-DAG by CDS2 (Mus musculus)


name: β1,2-agonists bind ADRB1,2 (Mus musculus)


name: AP1G2 binds HGS and CHMP2A (Canis familiaris)


name: OPN (osteopontin) degradation by MMP3, MMP7 (Canis familiaris)


name: p-6Y-VEGFR2 binds PLCG1 (Xenopus tropicalis)


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Mus musculus)


name: ATP + H2O + spermidine(out) <=> ADP + H(+) + phosphate + spermidine(in)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Canis familiaris)


name: AVP(20-28) binds AVPR1A,B (Gallus gallus)


name: 3,4,5-trihydroxybenzoate(out) + H(+)(out) = 3,4,5-trihydroxybenzoate(in) + H(+)(in)


name: Recruitment of p190RhoGEF to p-FAK (Caenorhabditis elegans)


name: CHDH oxidises Cho to BETALD (Caenorhabditis elegans)


name: Some HSPGs are secreted to the plasma membrane (Caenorhabditis elegans)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Mus musculus)


name: eIF2 activation (Caenorhabditis elegans)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Sus scrofa)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-tetracosanoylsphinganine + O2 <=> 2 Fe(III)-[cytochrome b5] + H2O + N-tetracosanoyl-(4R)-hydroxysphinganine


name: H(+)(out) + L-serine(in) + Na(+)(in) => H(+)(in) + L-serine(out) + Na(+)(out)


name: Formation of the Flap Intermediate on the C-strand (Rattus norvegicus)


name: acetyl-CoA + N-terminal L-methionyl-L-phenylalanyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-phenylalanyl-[protein]


name: (Z)-3-ureidoacrylate + H(+) + H2O = (Z)-3-aminoacrylate + CO2 + NH4(+)


name: SLCO4C1 mediates the transport of digoxin (Drosophila melanogaster)


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)


name: (2E)-pentadecenoyl-CoA + FADH2 => FAD + H(+) + pentadecanoyl-CoA


name: RHOC binds effectors at the plasma membrane (Canis familiaris)


name: H2O + L-alanine + xanthurenate => 3-hydroxy-L-kynurenine + pyruvate


name: Mcm4,6,7 trimer forms and associates with the replication fork (Dictyostelium discoideum)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Homo sapiens)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Canis familiaris)


name: CoA + H(+) + N-docosanoylsphinganine => docosanoyl-CoA + sphinganine


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine => a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine


name: IkB is ubiquitinated and degraded (Drosophila melanogaster)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Dictyostelium discoideum)


name: L-ascorbate(in) + monodehydro-L-ascorbate radical(out) <=> L-ascorbate(out) + monodehydro-L-ascorbate radical(in)


name: Formation of allysine by LOX (Mus musculus)


name: ATP + H(+) + octadecanoate = diphosphate + octadecanoyl-AMP


name: fumarate(in) + 2 H(+)(in) => fumarate(out) + 2 H(+)(out)


name: 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate = CO2 + deoxyviolacein + 2 H2O + NAD(+)


name: protein serine/threonine kinase activity


name: B4GALTs transfer Gal to a branch of keratan (Xenopus tropicalis)


name: 5alpha-androstan-3,17-dione + A = 5alpha-androst-1-ene-3,17-dione + AH2


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Sus scrofa)


name: 2 H(+) + Mg-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 <=> 3,8-divinyl protochlorophyllide a + 5 H2O + 3 NADP(+)


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Sus scrofa)


name: Recruitment of STATs (Xenopus tropicalis)


name: ferruginol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + pisiferate


name: Docking of Mature Replication Dependent Histone mRNA with the NPC (Rattus norvegicus)


name: 2,6-dichlorohydroquinone + chloride + glutathione disulfide + H(+) => 2,3,6-trichlorohydroquinone + 2 glutathione


name: PCSK9 binds PCSK9 inhibitors (Saccharomyces cerevisiae)


name: HSD11B1 hydrogenates PREDN to PREDL in hepatic cell (Gallus gallus)


name: PIP3 recruits PDPK1 to the membrane (Saccharomyces cerevisiae)


name: 3-aminopropanal + H2O2 + spermidine => H2O + O2 + thermospermine


name: Cleavage and polyadenylation of Intronless Pre-mRNA (Caenorhabditis elegans)


name: ATP + GTP <=> 3',2'-cGAMP + 2 diphosphate


name: lutein + O2 <=> (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R,6R)-hydroxy-alpha-ionone


name: Arachidonic acid  is converted to 12-oxoETE by ALOX12 (Canis familiaris)


name: CD55 (DAF) binds C3bBb, C4bC2a (Mus musculus)


name: HSF1 trimer translocates to the nucleus (Rattus norvegicus)


name: H2O + N-(2-phenylethyl)acetamide <=> 2-phenylethylamine + acetate


name: 8-chloroquinoline + A + H2O => 8-chloroquinolin-2(1H)-one + AH2


name: AH2 + chloroethene => A + chloride + ethene + H(+)


name: TP53RK phosphorylates TP53 (Rattus norvegicus)


name: 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide => 1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O


name: SUMOylation of RARA with SUMO2 (Bos taurus)


name: H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol <=> a fatty acid + H(+) + long chain acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: HIPK2 phosphorylates RUNX1 and EP300 (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + trichodiene


name: TP53 binds the complex of JMY, EP300 and TTC5 (Mus musculus)


name: SL (surrogate light chain) binds IgH to form pre-BCR (Sus scrofa)


name: CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine => 4-coumaroyl-CoA + S-adenosyl-L-methionine


name: CDP-ethanolamine + L-serine => CMP + H(+) + L-serine-phosphoethanolamine


name: 13-cis-retinol + a fatty acid + H(+) => an all-trans-retinyl ester + H2O


name: Phosphorylation of SHC1 by ERBB4 homodimers (Mus musculus)


name: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H2O => L-seryl-[protein] + N-acetyl-D-glucosamine


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Mus musculus)


name: Disassembly of tight junctions (Homo sapiens)


name: IFNG dimer binds IFNG inhibitors (Danio rerio)


name: CYP1B1 4-hydroxylates EST17b (Danio rerio)


name: 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O <=> (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: (-)-spiroviolene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: AUF1:mRNA complex is destroyed (Homo sapiens)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Danio rerio)


name: H(+) + isovitexin + UDP => apigenin + UDP-alpha-D-glucose


name: 4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O


name: RNF41 ubiquitinates activated ERBB3 (Homo sapiens)