name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Canis familiaris)


name: MT-MMPs are sorted to the plasma membrane (Canis familiaris)


name: L-tetrahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-tetrahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: an omega-methyl-medium-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] <=> an omega-hydroxy-medium-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: small conductance calcium-activated potassium channel activity


name: Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)


name: SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Bos taurus)


name: CREB3L3 translocates from the cytosol to the nucleus (Homo sapiens)


name: LIG1 binds APEX1 and PCNA at SSB (Dictyostelium discoideum)


name: maltose + H2O => 2 D-glucose (sucrase-isomaltase) (Canis familiaris)


name: Recruitment of HDAC1 by p130 (RBL2) (Drosophila melanogaster)


name: NF1 is degraded by the proteasome (Canis familiaris)


name: DVL is recruited to the receptor (Drosophila melanogaster)


name: Translocation of YAP1 to the nucleus (Mus musculus)


name: PTK6 binds ARAP1 (Caenorhabditis elegans)


name: PEX19:class I PMP binds PEX3 (Schizosaccharomyces pombe)


name: H(+) + pre-flavunoidine => 2,6,9-trimethyl-13-oxatetracyclo[6.3.1.1(6,9).0(1,5)]tridecane carbocation + N,N-dimethyl-cadaverine


name: CBL ubiquitinates FRS2 and FGFR4 (Mus musculus)


name: Keratin type I/type II heterodimers form tetramers (Sus scrofa)


name: L-tyrosine + S-adenosyl-L-methionine <=> 3-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: estrone 3-sulfate(out) + pentanoate(in) => estrone 3-sulfate(in) + pentanoate(out)


name: RANBP2 SUMOylates HDAC4 with SUMO2,3 (Drosophila melanogaster)


name: 3-oxodecanoyl-[ACP] + H(+) + NADPH = (3R)-hydroxydecanoyl-[ACP] + NADP(+)


name: (-)-kolavenyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: ESR1:ESTG and EP300 are recruited to TFF3 promoter (Homo sapiens)


name: AMP + diphosphate + L-tryptophyl-[peptidyl-carrier protein] => ATP + holo-[peptidyl-carrier protein] + L-tryptophan


name: 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Gallus gallus)


name: Autophosphorylation of SRC (Drosophila melanogaster)


name: Activation of Rho by LARG and PDZ-RhoGEF (Sus scrofa)


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Bos taurus)


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H2O => (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA


name: Insertion of connexons into the plasma membrane resulting in the formation of hemi-channels (Homo sapiens)


name: N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Sus scrofa)


name: 2 ATP + 2 cob(II)alamin + 2 H2O + reduced [electron-transfer flavoprotein] <=> 2 adenosylcob(III)alamin + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate


name: (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADH => (1S,2S,4R)-limonene-1,2-diol + NAD(+)


name: fructose transmembrane transporter activity


name: SLC2A5 transports fructose from extracellular region to cytosol (Homo sapiens)


name: Expression of FABP6 regulated by NR1H2,3 (Homo sapiens)


name: H2O + S-3-(hexan-1-ol)-L-cysteine <=> 3-sulfanyl-1-hexanol + NH4(+) + pyruvate


name: Production of AA by iPLA2 upon FCGR activation (Gallus gallus)


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol => (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone


name: phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Xenopus tropicalis)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ATP + H2O + nitrate(out) = ADP + H(+) + nitrate(in) + phosphate


name: O2 + torulene <=> 3-methyl-2-butenal + 4'-apo-beta-carotenal


name: (9Z)-octadecenoate + H(+) + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => H2O + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Danio rerio)


name: (E)-4-coumaroyl-AMP + diphosphate => (E)-4-coumarate + ATP + H(+)


name: CoA + eicosanoate + H(+) => eicosanoyl-CoA + H2O


name: adenosylcob(III)alamin 5'-phosphate + H2O <=> adenosylcob(III)alamin + phosphate


name: type 4 metabotropic glutamate receptor binding


name: ATP + CoA + dodecanedioate => AMP + diphosphate + dodecanedioyl-CoA


name: NUDT16 hydrolyses IDP to IMP (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Canis familiaris)


name: COS binds to SMO (Drosophila melanogaster)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Canis familiaris)


name: ADP + H(+) + sucrose => ADP-alpha-D-glucose + D-fructose


name: 4-hydroxybenzoate + H(+) + NADPH + O2 <=> 3,4-dihydroxybenzoate + H2O + NADP(+)


name: (9Z)-hexadecenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA


name: 6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)


name: Active G alpha (z) binds RGS proteins (Rattus norvegicus)


name: inulin fructotransferase (DFA-III-forming) activity


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + succinate


name: Recruitment of AP-2 complex and clathrin (Bos taurus)


name: 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O <=> 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + CoA + H(+)


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Homo sapiens)


name: Autocatalytic activation of MMP7 (Homo sapiens)


name: a 1-acyl-sn-glycero-2,3-cyclic phosphate + ethanolamine => a 1-acyl-sn-glycero-3-phosphoethanolamine


name: MEOS oxidizes ethanol to acetaldehyde (Rattus norvegicus)


name: YAP1 binds ZO-2 (TJP2) (Caenorhabditis elegans)


name: (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+) => H2O + O2 + tyramine


name: RNF34 or RFFL ubiquitinates phosphorylated TP53 (Rattus norvegicus)


name: arsenite + 2 Fe(III)-[cytochrome c] + H2O = arsenate + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Canis familiaris)


name: Phosphorylated ERF translocates to the cytosol (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: TCR complex interacts with peptide antigen-presenting MHC Class I (Mus musculus)


name: 4 Fe(III)-[cytochrome cL] + H2O + methanol = 4 Fe(II)-[cytochrome cL] + formate + 5 H(+)


name: TRIM21 ubiquitinates SQSTM1 (Rattus norvegicus)


name: (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acyl coenzyme A: isopenicillin N acyltransferase activity


name: H2O + NADPH = adenosine 2',5'-bisphosphate + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Sus scrofa)


name: 3-phenylsuccinyl-CoA + succinate => phenylsuccinate + succinyl-CoA


name: PNP trimer transforms RBV to T-CONH2 (Saccharomyces cerevisiae)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)


name: indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose <=> 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP


name: CBL-mediated ubiquitination of CIN85 (Mus musculus)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Mus musculus)


name: c-src associates with Cx43 in gap junctions (Sus scrofa)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Sus scrofa)


name: archaetidylserine + H(+) <=> archaetidylethanolamine + CO2


name: GNLY binds the bacterial cell surface in the phagosome (Canis familiaris)


name: H2O + imidazole-4-acetaldehyde + NAD(+) => 2 H(+) + imidazole-4-acetate + NADH


name: 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O => 6-deoxy-6-sulfo-D-gluconate


name: 3'-N-debenzoyltaxol + benzoyl-CoA => CoA + H(+) + taxol


name: rebaudioside D + UDP-alpha-D-glucose <=> H(+) + rebaudioside M + UDP


name: CHUK, IKBKB phosphorylate RIPK1 at S25 (Mus musculus)


name: S2P hydrolyzes SREBP1A,1C,2 (Canis familiaris)


name: 2xPPCS ligates PPanK with Cys (Xenopus tropicalis)


name: D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + H2O <=> D-glycero-alpha-D-manno-heptose 1-phosphate + phosphate


name: Recruitment of POLB to the AP site (Canis familiaris)


name: H(+)(in) + lactose(in) => H(+)(out) + lactose(out)


name: CO2 + diphosphate + nicotinate beta-D-ribonucleotide => 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate


name: 4-aminobutanoate(out) + n H(+)(in) <=> 4-aminobutanoate(in) + n H(+)(out)


name: beta-D-fructose 6-phosphate => D-arabino-hex-3-ulose 6-phosphate


name: Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Homo sapiens)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Caenorhabditis elegans)


name: FDPS dimer transfers IPPP to GPP (Saccharomyces cerevisiae)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: GPR31 is a receptor for 12(S)-HETE (Mus musculus)


name: Recruitment of BCAR1 to PTK2 complex (Mus musculus)


name: coenzyme M + methyl-Co(III)-[methylated-thiol-specific corrinoid protein] => Co(I)-[methylated-thiol-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus (Plasmodium falciparum)


name: ATP + N(6)-(D-erythrulosyl)-L-lysyl-[protein] <=> ADP + H(+) + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein]


name: Activation of MMP9 intermediate form by MMPs (Mus musculus)


name: 2 H(+)(in) + orotate(in) <=> 2 H(+)(out) + orotate(out)


name: 2-demethylmenaquinol-10 + S-adenosyl-L-methionine => H(+) + menaquinol-10 + S-adenosyl-L-homocysteine


name: aspartic acid methylthiotransferase activity


name: ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Danio rerio)


name: PPM1D dephosphorylates RUNX2 (Sus scrofa)


name: H2O + prostaglandin F2alpha 1-glyceryl ester <=> glycerol + H(+) + prostaglandin F2alpha


name: Methionine sulfoxide is oxidised to methionine sulfone (Homo sapiens)


name: 3-sulfanylpropanoate + O2 => 3-sulfinopropanoate + H(+)


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Sus scrofa)


name: Addition of a third mannose to the N-glycan precursor by ALG2 (Homo sapiens)


name: The Ligand:GPCR:Gz complex dissociates (Mus musculus)


name: ATP + L-serine <=> diphosphate + L-seryl-5'-AMP


name: acetyl-CoA + UDP-N-acetylbacillosamine <=> CoA + H(+) + UDP-N,N'-diacetylbacillosamine


name: a short-chain 3-oxoacyl-CoA + CoA => a short-chain fatty acyl-CoA + acetyl-CoA


name: ATP + coproporphyrinogen III(in) + H2O <=> ADP + coproporphyrinogen III(out) + H(+) + phosphate


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene <=> H2O + rhodopin


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Sus scrofa)


name: PKM dephosphorylates PEP to PYR (Rattus norvegicus)


name: Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Xenopus tropicalis)


name: anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine => 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine


name: ERBB2 KD mutants do not bind osimertinib (Homo sapiens)


name: SDH complex dehydrogenates succinate (Homo sapiens)


name: HDAC8 deacetylates histones (Sus scrofa)


name: Ub,pS335,S338,T NFE2L2 is degraded (Rattus norvegicus)


name: Collagen type V degradation by MMP2,9,10 (Xenopus tropicalis)


name: (2E)-3-(3-hydroxyphenyl)prop-2-enoate + H(+) + NADH + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD(+)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Bos taurus)


name: ULK1 phosphorylates Beclin-1 (Gallus gallus)


name: (1S)-1,25-dihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin] => 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: MAOB inhibitors bind MAOB:FAD (Mus musculus)


name: (2S)-3-sulfolactaldehyde + H2O + NADP(+) = (2S)-3-sulfolactate + 2 H(+) + NADPH


name: IL37(?-218):p-S423,S425-SMAD3 translocates to the nucleus (Homo sapiens)


name: SMAC (DIABLO) forms dimer (Rattus norvegicus)


name: cholesteryl hexadecanoate + CoA => cholesterol + hexadecanoyl-CoA


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + UDP-alpha-D-galactose => 1,2-di-(9Z-octadecenoyl)-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP


name: Dissociation of RAS:RAF complex (Caenorhabditis elegans)


name: Acitretin binds to RAR:RXR (Gallus gallus)


name: GAB1 phosphorylation by EGFR kinase (Mus musculus)


name: (2E)-dodecenoyl-[ACP] + H(+) + NADPH = dodecanoyl-[ACP] + NADP(+)


name: Ca2+ influx through voltage gated Ca2+ channels (Homo sapiens)


name: Cis-homodimerization of nectins (Gallus gallus)


name: a ganglioside GD1a + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GD1a + H(+) + UDP


name: ADP + H(+) + L-isoleucine(in) + phosphate => ATP + H2O + L-isoleucine(out)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Dictyostelium discoideum)


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Caenorhabditis elegans)


name: holothin + pseudomonoyl-CoA C <=> CoA + pseudomonic acid C--holothin


name: a ganglioside GM4 (d18:1(4E)) + CMP + H(+) => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate


name: TGFBR3(1-783) binds to TGFB1,TGFB2 (Homo sapiens)


name: Spontaneous hydrolysis of C3 thioester (Homo sapiens)


name: a long-chain 3-oxo-fatty acyl-CoA + H(+) + NADH => a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD(+)


name: PE is converted to PS by PTDSS2 (Sus scrofa)


name: UCP1 imports a proton (Xenopus tropicalis)


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Mus musculus)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Danio rerio)


name: CoA + H(+) + N-acetyl-S-benzyl-L-cysteine => acetyl-CoA + S-benzyl-L-cysteine


name: L-cysteinyl-[protein] + tetradecanoyl-CoA = CoA + S-tetradecanoyl-L-cysteinyl-[protein]


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Xenopus tropicalis)


name: RAC2 GAPs stimulate RAC2 GTPase activity (Rattus norvegicus)


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Gallus gallus)


name: L-histidine(out) + L-phenylalanine(in) => L-histidine(in) + L-phenylalanine(out)


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Xenopus tropicalis)


name: (indol-3-yl)butanoate + ATP + L-glutamine => (indol-3-yl)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: Growing HA is extruded from the cell by ABCC5 (Sus scrofa)


name: Molybdenum ion transfer onto molybdopterin (Sus scrofa)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Xenopus tropicalis)


name: Expression of cell division cycle 42 (Homo sapiens)


name: ATP + C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + H2O = AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + diphosphate + H(+) + phosphate


name: glyoxylate(out) + oxalate(in) => glyoxylate(in) + oxalate(out)


name: 5,6-dihydrouridine(20) in tRNA + NAD(+) <=> H(+) + NADH + uridine(20) in tRNA


name: H2O + progoitrin <=> (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: 2 a menaquinol + n H(+)(in) + O2 <=> 2 a menaquinone + n H(+)(out) + 2 H2O(in)


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Rattus norvegicus)


name: Expression of CCRN4L (NOCTURNIN) (Homo sapiens)


name: GRK2 sequesters activated Gq (Sus scrofa)


name: catechol + NAD(+) + nitrite => NADH + nitrobenzene + O2


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Homo sapiens)


name: ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Bos taurus)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Caenorhabditis elegans)


name: CTP(out) + GDP(in) <=> CTP(in) + GDP(out)


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Canis familiaris)


name: CPO transforms COPRO3 to PPGEN9 (Rattus norvegicus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine => a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + H(+) + S-adenosyl-L-homocysteine


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Rattus norvegicus)


name: p-S MAPK6 phosphorylates NCOA3 (Homo sapiens)


name: I(1,4,5)P3 binds ITPR3 tetramer (Mus musculus)


name: (E)-4-coumaraldehyde + CoA + NADP(+) = (E)-4-coumaroyl-CoA + H(+) + NADPH


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Rattus norvegicus)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Bos taurus)


name: Dopa is decarboxylated to dopamine (Drosophila melanogaster)


name: 2-hexadecanoylglycerol + H2O => glycerol + H(+) + hexadecanoate


name: FMNL2 binds CDC42:GTP (Caenorhabditis elegans)


name: Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (Rattus norvegicus)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Rattus norvegicus)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Dictyostelium discoideum)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Drosophila melanogaster)


name: cholesteryl (7Z)-octadecenoate + CoA => (7Z)-octadecenoyl-CoA + cholesterol


name: dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine => dTDP-alpha-D-desosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: ATR activation at DNA DSBs (Rattus norvegicus)


name: (E)-cinnamate + H(+) + NADPH + O2 = H2O + NADP(+) + trans-2-coumarate


name: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O2 <=> 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)


name: 2 H2O + L-cystine-bis-glycine => 2 glycine + L-cystine


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Plasmodium falciparum)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: 2-oxoglutarate + jasmonate + O2 => (1R,2R)-12-hydroxyjasmonate + CO2 + succinate


name: RAC2 GAPs stimulate RAC2 GTPase activity (Danio rerio)


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Rattus norvegicus)


name: daunorubicin + 2 H2O + NADP(+) => 13-dihydrodaunorubicin + H(+) + NADPH + O2


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Mus musculus)


name: Excess homocysteine yields homolanthionine and H2S (Canis familiaris)


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Schizosaccharomyces pombe)


name: H2O + phenylglyoxylyl-CoA => CoA + H(+) + phenylglyoxylate


name: GLYAT-like proteins transfer glycine to ST-CoA to form SUA (Homo sapiens)


name: 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Rattus norvegicus)


name: TTC19 clears UQCRFS1 fragments from Complex III (Caenorhabditis elegans)


name: p-STAT1 binds p-STAT3 (Canis familiaris)


name: an alpha-D-glucuronoside + H2O => an alcohol + D-glucuronate


name: HERC2 and PIAS4 are recruited to DNA DSBs (Drosophila melanogaster)


name: ABC7, mABC1 and mABC2 mediate heme transport (Gallus gallus)


name: an L-aminoacyl-L-amino acid + H2O <=> 2 an L-alpha-amino acid


name: eicosan-1-ol + hexadecanoyl-CoA => CoA + eicosanyl hexadecanoate


name: ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+) + NADPH => ergosterol + NADP(+)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Plasmodium falciparum)


name: chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) (Rattus norvegicus)


name: CSNK2-mediated phosphorylation of DVL (Homo sapiens)


name: CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein] => L-lysyl-[protein] + lactoyl-CoA


name: 2 H(+) + malonate + NADPH => 3-oxopropanoate + H2O + NADP(+)


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Canis familiaris)


name: estrone + H(+) + NADH => 17alpha-estradiol + NAD(+)


name: Autophosphorylation of BTK/ITK (Gallus gallus)


name: Cdh1:APC/C complex binds EHMT1:EHMT2 (Homo sapiens)


name: FOXO1,FOXO3 bind ABCA6 gene promoter (Homo sapiens)


name: CYP2F1 dehydrogenates 3-methylindole (Mus musculus)


name: glycine(in) + Na(+)(in) = glycine(out) + Na(+)(out)


name: 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pikromycin


name: Fibulin binds elastic fibres (Homo sapiens)


name: (S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) => ATP + H(+) + L-2-aminoadipate + NADPH


name: 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one <=> 3-isopropenyl-6-oxoheptanoate + H(+)


name: L-isoleucine(in) + Na(+)(in) = L-isoleucine(out) + Na(+)(out)


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Xenopus tropicalis)


name: ATP + L-erythrulose => ADP + H(+) + L-erythrulose 1-phosphate


name: AKR1B1 reduces Glc to D-sorbitol (Mus musculus)


name: H(+) + N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP => N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: decanoate + H(+) + holo-[ACP] => decanoyl-[ACP] + H2O


name: ATP + H2O + L-arabinose(out) = ADP + H(+) + L-arabinose(in) + phosphate


name: 5-methyldeoxycytidine 5'-phosphate + ATP = 5-methyldeoxycytidine diphosphate + ADP


name: (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + CO2 + CoA


name: Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Mus musculus)


name: 2-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate <=> 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: (3S)-1-hydroxy-3-methylpentan-2-one + H(+) + NADH + NH4(+) => (S)-isoleucinol + H2O + NAD(+)


name: SESN1,2 binds L-leucine and dissociates from GATOR2 (Bos taurus)


name: Two FPP molecules dimerize to form presqualene diphosphate (Xenopus tropicalis)


name: O2 + prosolanapyrone II => H2O2 + prosolanapyrone III


name: RAC2 translocates to the phagocytic vesicle membrane (Bos taurus)


name: Arachidonic acid is oxidised to PGG2 by PTGS2 (Rattus norvegicus)


name: alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: phosphatidylinositol bisphosphate phosphatase activity


name: ADP-D-ribose + diphosphate => ATP + D-ribose 5-phosphate + H(+)


name: L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Schizosaccharomyces pombe)


name: N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Caenorhabditis elegans)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Canis familiaris)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate


name: 5 AH2 + 2 H(+) + heme b + 4 O2 <=> 5 A + beta-staphylobilin + Fe(2+) + formaldehyde + 4 H2O


name: H2O + melibiose <=> D-galactose + D-glucose


name: diphosphate + RNA(n)-3'-uridine ribonucleotide => RNA(n) + UTP


name: NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841 (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(9Z,12Z,15Z-octadecatrienoyl)-4'-phosphopantetheine


name: PGAM5 dodecamer dephosphorylates p-S336-ME1 (Homo sapiens)


name: Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)


name: (9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphate => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: glucoraphanin + H2O => (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Caenorhabditis elegans)


name: a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GM1 (d18:1(4E)) + H2O


name: (2E)-butenoyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-(2E)-butenoyl-L-lysyl-[protein]


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Mus musculus)


name: decanoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = dec-9-enoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2',3'-cyclophospho-AMP + H2O = adenosine 2'-phosphate + H(+)


name: (R)-carnitine transmembrane transporter activity


name: octanoate + sphing-4-enine => H2O + N-octanoylsphing-4-enine


name: TLE forms non-functional complexes with AES (Homo sapiens)


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Dictyostelium discoideum)


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Homo sapiens)


name: allantoate + 2 H(+) + 2 H2O = (S)-ureidoglycolate + CO2 + 2 NH4(+)


name: RAC1:GTP binds NOX3 complex (Homo sapiens)


name: (20S)-protopanaxadiol + UDP-alpha-D-glucose <=> (20S)-ginsenoside C-K + H(+) + UDP


name: COX10 transforms heme to heme O (Canis familiaris)


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-dGTP => dGTP + H(+) + lactate


name: MYC positively regulates MAPKAPK5 gene expression (Homo sapiens)


name: METAP1/2 demethylates GNAT1 (Canis familiaris)


name: carminomycin + 2 H2O + NADP(+) => 13-dihydrocarminomycin + H(+) + NADPH + O2


name: osmolarity-sensing monoatomic cation channel activity


name: S100A7 or S100A7A binds Zn2+ (Homo sapiens)


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O => a 2-acyl-sn-glycero-3-phosphocholine + H(+) + hexanoate


name: Sprouty sequesters CBL away from active EGFR (Canis familiaris)


name: ZnT5 transports zinc into the golgi apparatus (Dictyostelium discoideum)


name: AMP + cremeomycin + diphosphate + H2O => 3-amino-2-hydroxy-4-methoxybenzoate + ATP + nitrite


name: CHRM2 binds CHRM2 antagonists (Drosophila melanogaster)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Homo sapiens)


name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y (Homo sapiens)


name: ULK1 Translocates to the mitochondria (Xenopus tropicalis)


name: NCOA2(869-1464) binds KAT6A(1-1118) (Drosophila melanogaster)


name: SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Caenorhabditis elegans)


name: Translocation of PTK2 to Focal complexes (Homo sapiens)


name: D-alanine transmembrane transporter activity


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Xenopus tropicalis)


name: Hydrolysis of PIP2 by PLCG (Gallus gallus)


name: chrysophanol-9-anthrone + O2 = chrysophanol + H2O


name: 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + S-adenosyl-L-methionine <=> 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: [thyroglobulin]-L-tyrosine + H(+) + H2O2 + iodide <=> [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA


name: a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + a 5'-end dephospho-ribonucleoside-RNA = a ribonucleotidyl-ribonucleotide-RNA + GMP + H(+)


name: 3',5'-di-O-methyltricetin + S-adenosyl-L-methionine = 3',4',5'-O-trimethyltricetin + H(+) + S-adenosyl-L-homocysteine


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Bos taurus)


name: 3'-phosphoadenylyl sulfate + androsterone = adenosine 3',5'-bisphosphate + androsterone 3alpha-sulfate + H(+)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Bos taurus)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Bos taurus)


name: all-trans-zeaxanthin + 2 UDP-alpha-D-glucose => 2 H(+) + 2 UDP + zeaxanthin bis(beta-D-glucoside)


name: (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal => all-trans-zeaxanthin + O2


name: IL35 binds IL6ST:IL6ST receptor (Sus scrofa)


name: UCHL1, UCHL3 cleave ubiquitin adducts (Xenopus tropicalis)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Drosophila melanogaster)


name: H(+) + N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: benzoate + S-adenosyl-L-methionine => methyl benzoate + S-adenosyl-L-homocysteine


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Drosophila melanogaster)


name: SHC1 in the RET complex is phosphorylated (Rattus norvegicus)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Sus scrofa)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Schizosaccharomyces pombe)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Rattus norvegicus)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Rattus norvegicus)


name: 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol => 4-O-[(D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)


name: ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA (Xenopus tropicalis)


name: [phosphate](n) + ATP <=> [phosphate](n+1) + ADP


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Canis familiaris)


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Gallus gallus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + CoA + H(+)


name: O2 + tetracosanoyl-CoA <=> (2E)-tetracosenoyl-CoA + H2O2


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Xenopus tropicalis)


name: holo-[citrate lyase ACP] + S-acetylphosphopantotheine => (R)-4'-phosphopantetheine + acetyl-[citrate lyase ACP]


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Bos taurus)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid A (E. coli) <=> a 2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A


name: D-arabinitol + NADP(+) <=> D-xylulose + H(+) + NADPH


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Dictyostelium discoideum)


name: KCNJs transport K+ from the extracellular region to cytosol (Rattus norvegicus)


name: a 5'-end triphospho-guanosine-ribonucleotide-snRNA + S-adenosyl-L-methionine = a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + S-adenosyl-L-homocysteine


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Canis familiaris)


name: D-sedoheptulose 7-phosphate => 2-epi-5-epi-valiolone + phosphate


name: H2O + L-tyrosine => NH4(+) + phenol + pyruvate


name: YAP1 binds TEAD1 (Caenorhabditis elegans)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-3-(O-farnesylgeranyl)glycerol 1-phosphate <=> 2,3-bis-O-(geranylfarnesyl)-sn-glycerol 1-phosphate + diphosphate


name: (E)-ferulate + ATP + CoA = (E)-feruloyl-CoA + AMP + diphosphate


name: AH2 + cannabichromenate => A + cannabinerolate


name: Phosphopantetheine conjugation of the ACP domain of FAS (Xenopus tropicalis)


name: Pro-HNP1-4 are cleaved to biologically active defensin (Rattus norvegicus)


name: Accumulation of M1 at the inner leaflet of the lipid bilayer (Homo sapiens)


name: LC3 binds ATG7 dimer (Caenorhabditis elegans)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Homo sapiens)


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Saccharomyces cerevisiae)


name: 5alpha-ergosta-7,22-diene-3beta,5-diol <=> ergosterol + H2O


name: RHOT1 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: H(+) + soyasapogenol B 3-O-beta-D-glucuronate + UDP => soyasapogenol B + UDP-alpha-D-glucuronate


name: 2 H(+) + NADPH + vanillate => H2O + NADP(+) + vanillin


name: (R)-carnitine(in) + Na(+)(in) => (R)-carnitine(out) + Na(+)(out)


name: Formation of the CTF18-RFC(7s) complex (Homo sapiens)


name: 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Saccharomyces cerevisiae)


name: (S)-allantoin(in) + H(+)(in) => (S)-allantoin(out) + H(+)(out)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)


name: (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO2 => (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+)


name: F-actin capping protein is a heterodimer (Bos taurus)


name: ferrous iron transmembrane transporter activity


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Rattus norvegicus)


name: chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate


name: acetyl-CoA + S-methyl-L-cysteine = CoA + H(+) + N-acetyl-S-methyl-L-cysteine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine


name: H(+)(in) + sucrose(out) = H(+)(out) + sucrose(in)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Rattus norvegicus)


name: BCMO1:Fe2+ cleaves betaC to atRAL (Danio rerio)


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Mus musculus)


name: MRN bound to shortened telomeres activates ATM (Sus scrofa)


name: ABCB4 transports PC from plasma membrane to extracellular region (Canis familiaris)


name: PIP3 binds to RhoA and activates it (Xenopus tropicalis)


name: RFC binding displaces Pol Alpha (Caenorhabditis elegans)


name: (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADH <=> H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+)


name: ITP(out) + UTP(in) <=> ITP(in) + UTP(out)


name: Latent TGF-beta-3 binds integrins (Gallus gallus)


name: (2E)-hexadecenoyl-CoA + H2O2 => hexadecanoyl-CoA + O2


name: YWHAZ binds p-CBY:CTNNB1 (Xenopus tropicalis)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA


name: A + O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine = AH2 + alstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Saccharomyces cerevisiae)


name: GNRHR binds GNRHR peptide agonists (Danio rerio)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate


name: PIP2 hydrolysis (Schizosaccharomyces pombe)


name: CRYM reduces P2C to PPCA (Saccharomyces cerevisiae)


name: 8-demethyl-8-(methylamino)riboflavin + H(+) + S-adenosyl-L-homocysteine => 8-amino-8-demethylriboflavin + S-adenosyl-L-methionine


name: D-sorbitol(out) + N(pros)-phospho-L-histidyl-[protein] <=> D-sorbitol 6-phosphate(in) + L-histidyl-[protein]


name: uridine(2604) in 23S rRNA = pseudouridine(2604) in 23S rRNA


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: an (omega-1)-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase]


name: alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose <=> alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: Src kinases phosphorylate VAV (Mus musculus)


name: 11a-hydroxytigecycline + H2O + NADP(+) => H(+) + NADPH + O2 + tigecycline


name: KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose (Homo sapiens)


name: 2-methylbutanamine + H2O + NAD(+) => 2-methylbutanal + H(+) + NADH + NH4(+)


name: P2Y9 receptor can bind to LPA (Canis familiaris)


name: Sulfite is oxidized to sulfate (Rattus norvegicus)


name: TPI1 isomerizes GA3P to DHAP (Dictyostelium discoideum)


name: CYP2J2 oxidises ARA (Drosophila melanogaster)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Drosophila melanogaster)


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Caenorhabditis elegans)


name: FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Homo sapiens)


name: HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane (Danio rerio)


name: Recruitment of DNA2 endonuclease to the C strand (Bos taurus)


name: BGN binds Collagen types I, VI, (IX) (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol = a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a monoacyl-sn-glycero-3-phosphocholine


name: NAD(+) + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + NADH + UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose


name: hydrogen sulfide + O-succinyl-L-homoserine = L-homocysteine + succinate


name: 1,6-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: 6-O-methyl-N-deacetylisoipecoside aglycone + D-glucose => 6-O-methyl-N-deacetylisoipecoside + H2O


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine => H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Caenorhabditis elegans)


name: STING recruits TBK1 and STAT6 (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate => beta-ylangene + diphosphate


name: Nascent SH localizes to Golgi membrane (Homo sapiens)


name: SFTPAs translocate from ER membrane to extracellular region (Gallus gallus)


name: 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-O-octadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Sus scrofa)


name: chlorophyllide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 7(1)-hydroxychlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 4-amino-4-deoxychorismate + L-glutamate => chorismate + L-glutamine


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Sus scrofa)


name: a ganglioside GM2 (d18:1(4E)) + H(+) + UDP => a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Xenopus tropicalis)


name: a short-chain 2,3-saturated fatty acyl-CoA + O2 = a short-chain (2E)-enoyl-CoA + H2O2


name: (E)-sinapaldehyde + CoA + NADP(+) = (E)-sinapoyl-CoA + H(+) + NADPH


name: 18S-resolvin E1 => (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: (20S)-ginsenoside F2 + UDP-alpha-D-glucose => (20S)-ginsenoside Rd + H(+) + UDP


name: CoA + hexadecanyl (9E)-octadecenoate => (9E)-octadecenoyl-CoA + hexadecan-1-ol


name: [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + H(+) + NADPH => [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + NADP(+) + phosphate


name: citrate(out) + tartrate(in) = citrate(in) + tartrate(out)


name: PRKD1,2,3 phosphorylates CERT1-2 (Danio rerio)


name: 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + H2O => 2-methylpropanoate + 2-oxopent-4-enoate + H(+)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Sus scrofa)


name: 2-oxoglutarate + DIBOA beta-D-glucoside + O2 => CO2 + succinate + TRIBOA beta-D-glucoside


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Bos taurus)


name: 4 Fe(III)-[cytochrome c] + H2O + hydroxylamine = 4 Fe(II)-[cytochrome c] + 5 H(+) + nitrite


name: SIAH1:UBE2L6:Ubiquitin binds SNCA (Homo sapiens)


name: 5-phosphomethyl-dUMP in DNA + putrescine => 5-N(alpha)-putrescinyl-dTMP in DNA + phosphate


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Canis familiaris)


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Danio rerio)


name: alpha-secretase cleaves the p75NTR extracellular domain (Bos taurus)


name: Activation of Ca permeable AMPA receptors (Danio rerio)


name: CoA + O-3-methylbutanoyl-(R)-carnitine => (R)-carnitine + 3-methylbutanoyl-CoA


name: AKT phosphorylates p21Cip1 and p27Kip1 (Caenorhabditis elegans)


name: Kinesins bind microtubules (Rattus norvegicus)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA


name: 2-amino-5-chloromuconate 6-semialdehyde => 2-amino-5-chlorophenol + O2


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)


name: ATXN3 deubiquitinates polyUb-PARK2 (Gallus gallus)


name: SH pentamer transports K+ (Homo sapiens)


name: 6-hydroxyquinolin-2(1H)-one + AH2 => A + H2O + quinolin-6-ol


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Bos taurus)


name: 3-dehydro-L-gulonate + NADP(+) = 2,3-dioxo-L-gulonate + H(+) + NADPH


name: (9Z)-octadecenoate + glycerol + H(+) => 2-(9Z-octadecenoyl)-glycerol + H2O


name: glyoxal + GTP => N(2)-(1-hydroxy-2-oxoethyl)-GTP


name: sulfur transfer to carrier protein (Mycobacterium tuberculosis)


name: 4-methyl-2-oxopentanoate + H(+) = 3-methylbutanal + CO2


name: histone H2AK5 acetyltransferase activity


name: p-S318,221-HuR binds mRNA (Gallus gallus)


name: an N,N-dimethylornithine lipid + S-adenosyl-L-methionine <=> an N,N,N-trimethylornithine lipid + H(+) + S-adenosyl-L-homocysteine


name: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate


name: AKR1B15 reduces EST17b to E1 (Drosophila melanogaster)


name: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> H(+) + menaquinol-8 + S-adenosyl-L-homocysteine


name: calcium-dependent protein kinase inhibitor activity


name: Formation of Ragulator complex (Xenopus tropicalis)


name: DENND3 exchanges GTP for GDP on RAB12 (Mus musculus)


name: phosphotransferase activity, paired acceptors


name: (S)-2-methyl-3-oxopropanoate + CoA + H2O + NAD(+) <=> H(+) + hydrogencarbonate + NADH + propanoyl-CoA


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Canis familiaris)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Canis familiaris)


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Danio rerio)


name: 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + zealexin A1 => (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced [NADPH--hemoprotein reductase]


name: DENND3 exchanges GTP for GDP on RAB12 (Dictyostelium discoideum)


name: THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 (Mus musculus)


name: cortisol + H(+) + NADPH => 20beta-dihydrocortisol + NADP(+)


name: Autophosphorylation of insulin receptor (Canis familiaris)


name: Phosphorylation of RAF (Rattus norvegicus)


name: (11S)-hydroperoxy-(4Z,7Z,9E,13Z,16Z,19Z)-docosahexaenoate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2


name: 4-O-demethylbarbatate + S-adenosyl-L-methionine => proatranorin I + S-adenosyl-L-homocysteine


name: melibiose(in) + Na(+)(in) => melibiose(out) + Na(+)(out)


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Canis familiaris)


name: (indol-3-yl)acetate + ATP + H(+) <=> (indol-3-yl)acetyl-AMP + diphosphate


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Homo sapiens)


name: PSD-95 binds NMDA receptor (Homo sapiens)


name: anthranilate + 2 ATP + O-methyl-L-tyrosine + S-adenosyl-L-methionine => (-)-4'-methoxycyclopeptine + 2 AMP + 2 diphosphate + 2 H(+) + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose => 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: Activated protein C:PROCR binds F2R (Mus musculus)


name: a 5'-end dephospho-ribonucleoside-RNA + phosphate => a 5'-end 5'-phospho-ribonucleoside-RNA + H2O


name: MAP3K5 phosphorylates MKK3 and MKK6 (Canis familiaris)


name: RRAGA,B exchanges GDP for GTP (Rattus norvegicus)


name: H2O + L-alaninamide => L-alanine + NH4(+)


name: chloride(out) + 2 hydrogencarbonate(in) + Li(+)(in) => chloride(in) + 2 hydrogencarbonate(out) + Li(+)(out)


name: Frataxin transfers Fe2+ to ACO2 (Bos taurus)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Canis familiaris)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Bos taurus)


name: Inhibition of integrin activation by sequestering PIP5KIgamma (Bos taurus)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Mus musculus)


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + H(+)


name: dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Plasmodium falciparum)


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate = (-)-7-epi-alpha-selinene + diphosphate


name: an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-alpha-D-galactose = an alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H(+) + UDP


name: IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)


name: Fusion of ERC and phagosome (Rattus norvegicus)


name: chorismate + NH4(+) => (2S)-2-amino-4-deoxychorismate + H2O


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Homo sapiens)


name: H(+) + heptan-4-one + NADPH + O2 => H2O + NADP(+) + propyl butanoate


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Rattus norvegicus)


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Drosophila melanogaster)


name: glycine + L-histidocholate => glycocholate + L-histidine


name: SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Bos taurus)


name: Phosphorylation of SLP-76 by p-SYK (Canis familiaris)


name: L-arginyl-[protein] + phosphate => H2O + N(omega)-phospho-L-arginyl-[protein]


name: ATP + H(+) + NADPH + nonanoate => AMP + diphosphate + NADP(+) + nonanal


name: USP28 deubiquitinates CLSPN and MYC (Schizosaccharomyces pombe)


name: Adenylate cyclase produces cAMP (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate => (+)-alpha-barbatene + diphosphate


name: UGT1A10 transfers GlcA from UDP-GlcA to GCTN (Homo sapiens)


name: Nef Binds and activates the Src-family tyrosine kinase Lck (Homo sapiens)


name: Expression of Lanosterol Demethylase (CYP51A1) (Homo sapiens)


name: Thrombin-activated PARs activate G12/13 (Sus scrofa)


name: 4-phospho-L-aspartate + H(+) + NADPH => L-aspartate 4-semialdehyde + NADP(+) + phosphate


name: (2R)-heptan-2-amine + H2O + NAD(+) = H(+) + heptan-2-one + NADH + NH4(+)


name: glutamine + H2O => glutamate + NH4+ [GLS] (Drosophila melanogaster)


name: Thrombin binding to GP1b:IX:V (Homo sapiens)


name: H2O + nicotinamide <=> NH4(+) + nicotinate


name: CHRM1,3,5 bind acetylcholine (Mus musculus)


name: 3,3',5-triiodo-L-thyronine(out) + L-tyrosine(in) <=> 3,3',5-triiodo-L-thyronine(in) + L-tyrosine(out)


name: PKR binds activating host RNA (Caenorhabditis elegans)


name: Interaction of E3 with substrate and E2-Ub complex (Danio rerio)


name: L-arginine + O2 => 4-guanidinobutanamide + CO2 + H2O


name: Calmodulin dissociates KRAS4B from the plasma membrane (Canis familiaris)


name: GSK3 phosphorylates p-GLI3 (Gallus gallus)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Rattus norvegicus)


name: SUMOylation of EP300 with SUMO1 (Gallus gallus)


name: ASPG hydrolyses L-Asn to L-Asp (Caenorhabditis elegans)


name: DCD is processed into DCD(63-110) (Homo sapiens)


name: NAD(+) + UDP-alpha-D-glucose = H(+) + NADH + UDP-3-oxo-alpha-D-glucose


name: IL37, IL37(?-218) translocates from cytosol to extracellular region (Bos taurus)


name: D-mannitol(out) + N(pros)-phospho-L-histidyl-[protein] => D-mannitol 1-phosphate(in) + L-histidyl-[protein]


name: 2-dehydropantoate <=> 3-methyl-2-oxobutanoate + formaldehyde


name: 1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H(+)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Mus musculus)


name: 3,4-dihydroxybenzaldehyde + acetyl-CoA => 3-hydroxy-3-(3,4-dihydroxyphenyl)propanoyl-CoA


name: D-galactose + NAD(+) = D-galactono-1,5-lactone + H(+) + NADH


name: Release of GNB5:RGS dimers from CCT/TRiC (Bos taurus)


name: Oxidative damage to the AP site (Caenorhabditis elegans)


name: H(+) + L-cysteinyl-[protein] + lactate => H2O + S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein]


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Rattus norvegicus)


name: (R)-carnitine + 2-methylbutanoyl-CoA => CoA + O-2-methylbutanoyl-(R)-carnitine


name: gibberellin A4 + S-adenosyl-L-methionine => O-methyl gibberellin A4 + S-adenosyl-L-homocysteine


name: n 3'-phosphoadenylyl sulfate + chondroitin 4'-sulfate = n adenosine 3',5'-bisphosphate + chondroitin 4',6'-bissulfate + n H(+)


name: Basigin binds MCT1, MCT3 and MCT4 (Xenopus tropicalis)


name: CO2 + itaconate => H(+) + trans-aconitate


name: Endophilins recruit synaptojanins to the clathrin-coated pit (Gallus gallus)


name: Cleaved KMT2A dimers translocate to the nucleus (Rattus norvegicus)


name: H2O + N-(2-phenylethyl)acetamide = 2-phenylethylamine + acetate


name: G alpha (q) inhibits PI3K alpha (Bos taurus)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O <=> (11R,12R)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: 2 glutathione + thiosulfate => glutathione disulfide + 2 H(+) + hydrogen sulfide + sulfite


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Dictyostelium discoideum)


name: adenine + alpha-D-ribose 1-methylphosphonate 5-triphosphate => ATP + methylphosphonate


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc6S derivative + GDP-beta-L-fucose => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc6S derivative + GDP + H(+)


name: BP230 is recruited to the hemidesmosome (Homo sapiens)


name: PI is exchanged with PC by PITPNB (Rattus norvegicus)


name: GUCA binds Ca2+ to form GUCA:Ca2+ (Bos taurus)


name: PSAP(195-273) forms a dimer (Canis familiaris)


name: TRAIL:TRAIL receptor trimers bind FADD (Gallus gallus)


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Homo sapiens)


name: (R)-3-hydroxybutanoate(out) + H(+)(out) = (R)-3-hydroxybutanoate(in) + H(+)(in)


name: anthocyanin A10 + malonyl-CoA => anthocyanin A11 + CoA


name: 7,8-dihydropteroate + H(+) + NADH => (6S)-5,6,7,8-tetrahydropteroate + NAD(+)


name: STAT5 is recruited by JAK2 (Gallus gallus)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Saccharomyces cerevisiae)


name: Histone H3.3 deposition at telomere (Mus musculus)


name: UDP-glucose is oxidised to UDP-glucuronate (Caenorhabditis elegans)


name: N-myristoylation of eNOS (Saccharomyces cerevisiae)


name: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)


name: 2-oxoglutaramate + glycine => glyoxylate + L-glutamine


name: IRE1 binds IRE1 forming dimer (Gallus gallus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-octanoylsphinganine + O2 <=> 2 Fe(III)-[cytochrome b5] + H2O + N-octanoyl-4-hydroxysphinganine


name: ADP + H(+) + phosphate + sulfate(in) => ATP + H2O + sulfate(out)


name: Complement factor B binds to surface-bound C3b fragment (Gallus gallus)


name: (4Z,15Z)-bilirubin IXalpha + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> biliverdin IXalpha + reduced coenzyme F420-(gamma-L-Glu)(n)


name: O2 + 4 semiviriditoxin <=> 2 (M)-viriditoxin + 2 H2O


name: SRC-1 bound to ARRB2 is not activated (Homo sapiens)


name: H2O + N-acetyl-L-aspartyl-L-glutamate => L-glutamate + N-acetyl-L-aspartate


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Bos taurus)


name: Phosphorylation of MDM4 by ATM (Mus musculus)


name: eNOS:NOSIP translocation from caveolae to intracellular compartments (Sus scrofa)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 2 O2 = 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Sus scrofa)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Gallus gallus)


name: L-phenylalanine(out) + L-tryptophan(in) <=> L-phenylalanine(in) + L-tryptophan(out)


name: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+) => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Plasmodium falciparum)


name: PLC gamma 2-mediated PIP2 hydrolysis (Bos taurus)


name: 2,5-dioxopentanoate + H2O + NAD(+) = 2-oxoglutarate + 2 H(+) + NADH


name: (2Z,6Z)-farnesyl diphosphate => (E)-beta-farnesene + diphosphate


name: 1,8-cineole + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-exo-hydroxy-1,8-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (1R,4R)-camphor + H(+) + NADPH + O2 <=> (+)-6-exo-hydroxycamphor + H2O + NADP(+)


name: GPR35 binds kynurenic acid (Danio rerio)


name: A4GALT transfers galactose to LacCer (Rattus norvegicus)


name: RAC3 GAPs stimulate RAC3 GTPase activity (Sus scrofa)


name: an anthocyanidin + H(+) + UDP-alpha-D-glucose = an anthocyanidin 3-O-beta-D-glucoside + UDP


name: a ganglioside GQ1c + CMP + H(+) => a ganglioside GT1c + CMP-N-acetyl-beta-neuraminate


name: BPHL hydrolyses VACV to ACV (Homo sapiens)


name: N(2)-(1-hydroxy-2-oxopropyl)-GMP => GMP + methylglyoxal


name: PIP3 binds to RhoA and activates it (Sus scrofa)


name: diphosphate + limonene => (2E)-geranyl diphosphate


name: (9Z)-octadecenoyl-CoA + 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate => (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: 2-hydroxydocosanoate + 2 Fe(III)-[cytochrome b5] + H2O => docosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H2O = alpha-D-glucose 1-phosphate + alpha-D-mannose derivative + H(+)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Canis familiaris)


name: KRAS4B recycles to the plasma membrane (Bos taurus)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Caenorhabditis elegans)


name: 3-deoxyfructose + NADP(+) <=> 3-deoxyglucosone + H(+) + NADPH


name: NEDD4L ubiquitinates SMAD2/3 (Bos taurus)


name: CO2 + menaquinol-8 => formate + H(+) + menaquinone-8


name: COX7A1 gene expression is stimulated by EBF2 (Homo sapiens)


name: Homodimerization  of DFF40 (Canis familiaris)


name: Interaction of MyoD:E protein with MEF2 (Mus musculus)


name: dodecanoyl-CoA + H(+) + malonyl-[ACP] <=> 3-oxotetradecanoyl-[ACP] + CO2 + CoA


name: ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine = (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine


name: butanoate(in) + estrone 3-sulfate(out) => butanoate(out) + estrone 3-sulfate(in)


name: 2-methoxy-4-vinylphenol + CO2 => (E)-ferulate + H(+)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 26-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-2-(11Z,14Z,17Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = (11Z,14Z,17Z-eicosatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Neurolysin degrades neurotensin (Rattus norvegicus)


name: (+)-alpha-santalene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Gallus gallus)


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Canis familiaris)


name: 1,2-didecanoylglycerol + H2O => decanoate + decanoylglycerol + H(+)


name: (2E)-octenal + H2O + NAD(+) <=> (2E)-octenoate + 2 H(+) + NADH


name: Collagen type III degradation by MMP14 (Xenopus tropicalis)


name: Exocytosis of azurophil granule membrane proteins (Caenorhabditis elegans)


name: MMP14 (MT1-MMP) binds TIMP2 (Sus scrofa)


name: ATP + viomycin => ADP + H(+) + O-phosphoviomycin


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + AH2 + O2 => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + A + 2 H2O


name: USP9X binds Ub:PEX5L (Drosophila melanogaster)


name: a cardiolipin + ethanolamine => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)


name: ATP + L-threonyl-[rhodopsin] = ADP + H(+) + O-phospho-L-threonyl-[rhodopsin]


name: hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Homo sapiens)


name: ATXN3 deubiquitinates polyUb-PARK2 (Canis familiaris)


name: (E)-hex-2-en-1-ol + NADP(+) => (E)-hex-2-enal + H(+) + NADPH


name: cAMP activates EPAC2 (Saccharomyces cerevisiae)


name: N-octanoyl-(2S)-hydroxyglycine = glyoxylate + octanamide


name: ASPA deacetylates NAA to acetate and L-aspartate (Bos taurus)


name: IMPAD1 hydrolyses PAP to AMP (Mus musculus)


name: CYP3A4, CYP2B6 bind ritonavir (Mus musculus)


name: 2 Fe(III)-[cytochrome] + H2O + nicotinate = 6-hydroxynicotinate + 2 Fe(II)-[cytochrome] + 2 H(+)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Homo sapiens)


name: 2-oxoglutarate + L-phosphinothricin => 4-(hydroxy(methyl)phosphoryl)-2-oxobutanoate + L-glutamate


name: Galanin receptors can bind galanin (Mus musculus)


name: 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O => a fatty acid + acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+)


name: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: Resynthesis of excised residue by POLB (Xenopus tropicalis)


name: ATP + L-histidyl-[protein] => ADP + H(+) + N(tele)-phospho-L-histidyl-[protein]


name: 2-chlorobenzoate + H(+) + NADH + O2 <=> catechol + chloride + CO2 + NAD(+)


name: Expression of peptide bound class I MHC on cell surface (Homo sapiens)


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Bos taurus)


name: Sulfhydrylation and ring cleavage of precursor Z (Homo sapiens)


name: isovitexin + UDP-alpha-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Bos taurus)


name: WLS binds WNT ligands in the Golgi (Canis familiaris)


name: 3',3'-c-di-GMP + H2O <=> 5'-phosphoguanylyl(3'->5')guanosine + H(+)


name: SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Bos taurus)


name: all-trans-retinol + an acyl-CoA <=> an all-trans-retinyl ester + CoA


name: glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 (Rattus norvegicus)


name: VDR agonists bind VDR (Canis familiaris)


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Xenopus tropicalis)


name: dihydroferuloyl-CoA + NADP(+) = (E)-feruloyl-CoA + H(+) + NADPH


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Canis familiaris)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)


name: thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Xenopus tropicalis)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Xenopus tropicalis)


name: Cross-linking of FCGRIIIA with IgG-coated Ag (Mus musculus)


name: Activated IKK phosphorylates I-kappaB (Rattus norvegicus)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Gallus gallus)


name: 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Canis familiaris)


name: CTP(out) + dGTP(in) = CTP(in) + dGTP(out)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = (11R,12R)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: (2E,6E)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate


name: G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) (Danio rerio)


name: 4'-hydroxyacetophenone + H(+) + NADPH + O2 <=> 4-acetoxyphenol + H2O + NADP(+)


name: a monoacyl-sn-glycero-3-phosphocholine + H2O <=> a monoacylglycerol + H(+) + phosphocholine


name: CDK and DDK associate with the Mcm10:pre-replicative complex (Mus musculus)


name: 4-acetoxybenzaldehyde + H(+) + NADH => 4-acetoxybenzyl alcohol + NAD(+)


name: ASIC trimers:H+ transport extracellular Na+ to cytosol (Mus musculus)


name: BIRC(cIAP1/2) ubiquitinates RIPK1 (Xenopus tropicalis)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Rattus norvegicus)


name: p-SHC1 binds integrin alpha5beta1:fibronectin (Bos taurus)


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Canis familiaris)


name: voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization


name: Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)


name: ATP + ethanolamine + L-glutamate = ADP + gamma-L-glutamylethanolamide + H(+) + phosphate


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Canis familiaris)


name: MEF2C gene expression is inhibited by MECP2 (Homo sapiens)


name: SULT1A3,4 dimers sulfate DA to DAOS (Canis familiaris)


name: Beta-catenin recruits SMARCA4 (Danio rerio)


name: L-allo-threonine + NADP(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADPH


name: Zinc is an agonist of GPR39 (Mus musculus)


name: (9Z,12Z)-octadecadien-1-ol + 1-hexadecanoylglycerone 3-phosphate => 1-O-(9Z,12Z)-octadecadienylglycerone 3-phosphate + H(+) + hexadecanoate


name: all-trans-hexaprenyl diphosphate <=> diphosphate + talaropentaene


name: STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+)


name: CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 (Drosophila melanogaster)


name: glutathione(in) + 3 Na(+)(in) => glutathione(out) + 3 Na(+)(out)


name: 4-hydroxybenzoate + all-trans-nonaprenyl diphosphate => 4-hydroxy-3-all-trans-nonaprenylbenzoate + diphosphate


name: 2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine <=> 2-heptyl-1-methoxy-4(1H)-quinolinone + H(+) + S-adenosyl-L-homocysteine


name: diphosphate + syn-copalol => 9alpha-copalyl diphosphate + H2O


name: allokutznerene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Saccharomyces cerevisiae)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Canis familiaris)


name: (S)-malate + succinyl-CoA = (S)-malyl-CoA + succinate


name: a CDP-1,2-diacyl-sn-glycerol + choline => a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: 16alpha-hydroxygypsogenate + UDP-alpha-D-glucose <=> 16alpha-hydroxygypsogenate 28-beta-D-glucoside + UDP


name: (2Z,6E,10E)-geranylgeranyl diphosphate + diphosphate => (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate


name: factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer (Gallus gallus)


name: deoxylimonoate + H2O <=> deoxylimononate D-ring-lactone + H(+)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-valyl-[protein] => acetyl-CoA + N-terminal L-valyl-[protein]


name: (11R)-methyl carlactonoate + 2-oxoglutarate + O2 = (11R)-hydroxymethyl carlactonoate + CO2 + succinate


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Bos taurus)


name: JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin (Homo sapiens)


name: p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Xenopus tropicalis)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+) => D-methionine + H2O + O2


name: 5,6-dihydrothymine + H2O => 3-(carbamoylamino)-2-methylpropanoate + H(+)


name: a 1-acyl-sn-glycero-3-phosphate + dodecanoyl-CoA <=> a 1-acyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: fumonisin B1 + 2 H2O => (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + 2 H(+) + 2 tricarballylate


name: myo-inositol + O2 <=> D-glucuronate + H(+) + H2O


name: Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Gallus gallus)


name: glyoxal + H2O + O2 => glyoxylate + H(+) + H2O2


name: WNT ligands traffic to the Golgi (Caenorhabditis elegans)


name: Activation of STAT5a/b by JAK2 (Gallus gallus)


name: 2'-deoxyguanosine + ATP <=> ADP + dGMP + H(+)


name: diphosphate + isopimara-8(14),15-diene => (+)-copalyl diphosphate


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Sus scrofa)


name: FAD + H(+) + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + FADH2


name: (24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O => (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA


name: 3-oxochol-4-en-22-oyl-CoA + A <=> 3-oxochola-4,17-dien-22-oyl-CoA + AH2


name: 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: 2,3-dihydroxy-p-cumate + H(+) + NADH => (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+)


name: Co-precorrin-6B + NAD(+) => Co-precorrin-6A + H(+) + NADH


name: 5,6-dihydrouridine(20b) in tRNA + NADP(+) = H(+) + NADPH + uridine(20b) in tRNA


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Mus musculus)


name: Formation of the Spliceosomal E complex (Rattus norvegicus)


name: a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1alpha + CMP + H(+)


name: naphthalene-1,2-diol + O2 => 2-hydroxychromene-2-carboxylate + H(+)


name: H(+) + NADH + O2 + phenol = catechol + H2O + NAD(+)


name: Interleukin-27 dissociates from Interleukin-27 receptor (Mus musculus)


name: H(+) + malonyl-[ACP] + octanoyl-CoA = 3-oxodecanoyl-[ACP] + CO2 + CoA


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Plasmodium falciparum)


name: adenosine(1832) in 18S rRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(1832) in 18S rRNA + S-adenosyl-L-homocysteine


name: TNF-α is cleaved by ADAM17 (TACE) (Homo sapiens)


name: TGFBR3_mem cleavage by MMPs (Homo sapiens)


name: H2O + N(1)-acetylspermine + O2 => H2O2 + N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine


name: IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Homo sapiens)


name: The Ligand:GPCR:G12/13 complex dissociates (Canis familiaris)


name: H2O + O2 + spermidine <=> 3-aminopropanal + H2O2 + putrescine


name: 5-oxo-L-proline(out) + 2 Na(+)(out) = 5-oxo-L-proline(in) + 2 Na(+)(in)


name: PRC1 SUMOylates CASP8AP2 with SUMO1 (Sus scrofa)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)


name: ATP + beta-alanine + dopamine = AMP + beta-alanyl-dopamine + diphosphate + H(+)


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Bos taurus)


name: CHUK, IKBKB phosphorylate CYLD at S418 (Drosophila melanogaster)


name: digoxin + 2 Fe(II)-[cytochrome c] + 3 H(+) => dihydrodigoxin + 2 Fe(III)-[cytochrome c]


name: Na(+)(out) + xanthine(out) = Na(+)(in) + xanthine(in)


name: FOXF1 binds CDH11 gene promoter (Homo sapiens)


name: ATP + beta-nicotinamide D-ribonucleotide + H(+) <=> diphosphate + NAD(+)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Bos taurus)


name: CS acetylates OA to citrate (Danio rerio)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Bos taurus)


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Danio rerio)


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Gallus gallus)


name: H2O + N(1),N(12)-diacetylspermine + O2 <=> 3-acetamidopropanal + H2O2 + N(1)-acetylspermidine


name: SHP2 dephosphorylates Tyr 992 on EGFR (Homo sapiens)


name: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H(+)


name: siderophore-iron transmembrane transporter activity


name: TFIIIC-class transcription factor complex binding


name: Kinetochore capture of astral microtubules (Xenopus tropicalis)


name: 5'-deoxyadenosine + A + dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + H(+) + L-methionine + NH4(+) => AH2 + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + S-adenosyl-L-methionine


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Gallus gallus)


name: ADP + beta-alanyl-L-arginine + H(+) + phosphate => ATP + beta-alanine + L-arginine


name: cyclohexanecarbaldehyde + hydrogen cyanide = (2S)-2-cyclohexyl-2-hydroxyacetonitrile


name: COMT transfers Met to DOPAC to form HVA (Xenopus tropicalis)


name: Formation of the SET1B complex (Schizosaccharomyces pombe)


name: peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate


name: O2 + preaspterpenacid acid I + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + preaspterpenacid acid II


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Mus musculus)


name: HOXD3 gene is transcribed (Homo sapiens)


name: choline(out) + n H(+)(in) <=> choline(in) + n H(+)(out)


name: fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 (Canis familiaris)


name: S-adenosyl-L-methionine + uridine(1498) in 16S rRNA => H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine


name: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate


name: p-PKR dimer phosphorylates PTPN2 (Danio rerio)


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: a 3'-end 3'-phospho-ribonucleotide-RNA + H(+) + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] => a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + L-histidyl-[RNA ligase]


name: H(+) + NADPH + O2 + phenylacetone => benzyl acetate + H2O + NADP(+)


name: ATP + H2O + spermidine(out) => ADP + H(+) + phosphate + spermidine(in)


name: dihydroprecondylocarpine acetate + NADPH <=> (+)-vincadifformine + acetate + NADP(+)


name: Phosphorylation of BRCA1-A complex at multiple sites by ATM (Rattus norvegicus)


name: (R)-pantoate + ATP + beta-alanine => (R)-pantothenate + AMP + diphosphate + H(+)


name: CMP-N-acetyl-beta-neuraminate + N-acetyl-beta-lactosamine => CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine


name: CTP(out) + UMP(in) <=> CTP(in) + UMP(out)


name: 2'-deoxyadenosine + H(+) + H2O <=> 2'-deoxyinosine + NH4(+)


name: 2-oxoglutarate(out) + heptanedioate(in) <=> 2-oxoglutarate(in) + heptanedioate(out)


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + acetyl-CoA <=> 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: (R)-6-hydroxynicotine + O2 = 6-hydroxy-N-methylmyosmine + H2O2


name: DBI, ACBD7 bind MCFA-CoA and LCFA-CoA (Mus musculus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Bos taurus)


name: ADP + CoA + H(+) + N(4)-acetylcytidine(34) in elongator tRNA(Met) + phosphate => acetyl-CoA + ATP + cytidine(34) in elongator tRNA(Met) + H2O


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Sus scrofa)


name: Superoxide reduces cytochrome c (Drosophila melanogaster)


name: 2-oxoglutarate + melatonin + O2 => 2-hydroxymelatonin + CO2 + succinate


name: Formation of eIF2:GDP:eIF2B intermediate (Bos taurus)


name: 2-oxoglutarate + O2 + UMP = CO2 + phosphate + succinate + uridine-5'-aldehyde


name: ITCH ubiquitinates DTX (Drosophila melanogaster)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Homo sapiens)


name: Neurofascin interacts with syntenin-1 (Bos taurus)


name: 2-oxoglutarate + L-asparaginyl-[ankyrin-repeat domain protein] + O2 => (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid + 8 oxidized 2[4Fe-4S]-[ferredoxin] => a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate <=> di-trans,poly-cis-polyprenyl diphosphate + n diphosphate


name: 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + H(+) + NADPH <=> 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-4H,6H,7H,8H-pyrrolo[1,2-a]pyrazine + NADP(+)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(N-acetyl-alpha-D-neuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+)


name: SGMS2 transfers phosphocholine onto ceramide (Caenorhabditis elegans)


name: ITPA hydrolyses ITP to IMP (Drosophila melanogaster)


name: SRC family kinases phosphorylate ERBB2 (Gallus gallus)


name: HJURP:CENPA complex localizes to the centromere (Homo sapiens)


name: Formation of MSH2:MSH3 Complex (Mus musculus)


name: Recruitment of DNA2 endonuclease to the C strand (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + 1-octanoylglycerol = 1-octanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: (2Z,6E)-farnesyl diphosphate + H2O <=> (6E)-nerolidol + diphosphate


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O => a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H(+)


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Drosophila melanogaster)


name: intramolecular oxidoreductase activity, transposing S-S bonds


name: RNA demethylases demethylate N6-methyladenosine RNA (Mus musculus)


name: Recruitment of CDK11p58 to the centrosomes (Sus scrofa)


name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Rattus norvegicus)


name: H(+) + N(6)-acetyl-L-lysyl-[protein] + phosphate => acetyl phosphate + L-lysyl-[protein]


name: 1,2-di-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphoethanolamine


name: an R-cob(III)alamin(in) <=> an R-cob(III)alamin(out)


name: COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates (Bos taurus)


name: 2-acyl LPG is acylated to PG by LPGAT (Mus musculus)


name: GAA hydrolyzes lysosomal glycogen (Homo sapiens)


name: (2E)-hexadecenedioyl-CoA + H2O => (3S)-hydroxyhexadecanedioyl-CoA


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Gallus gallus)


name: GDP-beta-L-fucose + Lc4Cer = a lactoside III(4)-a-Fuc-Lc4Cer + GDP + H(+)


name: H2O2 + phenylglyoxylate => mandelate + O2


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + veratrole = 3-methoxyphenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: (2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2


name: aclacinomycin A + O2 = aclacinomycin Y + H2O2


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) <=> 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + [thyroglobulin]-3-iodo-L-tyrosine + H2O2 = [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O


name: D-glutamine + H2O + O2 = 2-oxoglutaramate + H2O2 + NH4(+)


name: MITF-M dimer binds the ASAH1 gene (Homo sapiens)


name: PA is converted to CDP-DAG by CDS2 (Bos taurus)


name: SENP1,2,5 proteolytically process SUMO1 (Rattus norvegicus)


name: NSF ATPase activity dissociates cis-SNARE (Drosophila melanogaster)


name: (2E)-butenoyl-CoA + CO2 + Na(+)(out) => (2E)-glutaconyl-CoA + H(+) + Na(+)(in)


name: TBC1D3 associates with RAB5 (Homo sapiens)


name: SUMOylation of PML with SUMO3 (Drosophila melanogaster)


name: factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) (Gallus gallus)


name: 2 fonsecin B + H(+) + NADPH + O2 <=> bifonsecin B + 2 H2O + NADP(+)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA => 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Saccharomyces cerevisiae)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Mus musculus)


name: Cis-Heterodimerization of nephrin and KIRREL (Bos taurus)


name: p75NTR and RHOA-GDI interact (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + a mannosylinositol-1-phospho-N-acyl-sphingoid base => a 1,2-diacyl-sn-glycerol + an inositol phosphomannosylnositol-1-phospho-N-acylsphingoid base


name: H2O + N-(11Z-eicosenoyl)-sphinganine => (11Z)-eicosenoate + sphinganine


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Homo sapiens)


name: GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate (Homo sapiens)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + L-serine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine + ethanolamine


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O => 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Bos taurus)


name: beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP-alpha-D-galactofuranose => [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 H(+) + 28 UDP


name: RHOB GAPs stimulate RHOB GTPase activity (Xenopus tropicalis)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Drosophila melanogaster)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + NAD(+) <=> androst-4-ene-3,11,17-trione + H(+) + NADH


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-leucine + O2 = (2S)-4-methyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanoate + H(+) + H2O2


name: Formation of histidino-hydroxylysinonorleucine cross-links (Sus scrofa)


name: SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol <=> a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester


name: 2-oxoglutarate + hexyl sulfate + O2 <=> CO2 + H(+) + hexanal + succinate + sulfate


name: 4-hydroxy-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA => 2 H(+) + hexadecanoyl-CoA + 2 malonyl-CoA


name: TP53 binds the TP53AIP1 gene (Homo sapiens)


name: K63polyUb-TAK1 autophosphorylates (Homo sapiens)


name: cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (25R)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: D-ribose 2,5-bisphosphate + H(+) => alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Bos taurus)


name: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity


name: (22R,23R)-22,23-dihydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase] => (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (2Z,6Z)-farnesyl diphosphate <=> (E)-beta-farnesene + diphosphate


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Saccharomyces cerevisiae)


name: IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Canis familiaris)


name: all-trans-13,14-dihydroretinol + NAD(+) => all-trans-13,14-dihydroretinal + H(+) + NADH


name: 3-dimethylallyl-4-hydroxyphenylpyruvate + diphosphate => 3-(4-hydroxyphenyl)pyruvate + dimethylallyl diphosphate


name: an N-octadecanoyl-sphingoid base + CoA + H(+) => a sphingoid base + octadecanoyl-CoA


name: follicle-stimulating hormone receptor binding


name: ZnT8 transports zinc into the Golgi apparatus (Plasmodium falciparum)


name: Translocation of CaN:CaM:NFAT to nucleus (Xenopus tropicalis)


name: Basigin binds CD98 complex (Canis familiaris)


name: H(+)(in) + L-isoleucine(out) => H(+)(out) + L-isoleucine(in)


name: RNASEs bind bacterial LPS, PGN (Homo sapiens)


name: 2-methylbutanoyl-CoA + CO2 + NADH => (S)-3-methyl-2-oxopentanoate + CoA + NAD(+)


name: CDK5:p25 phosphorylates PRDX2 (Homo sapiens)


name: Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP (Homo sapiens)


name: NAGLU hydrolyses heparan chain(2) (Homo sapiens)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Bos taurus)


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)


name: Inactivation of APC/C via CDC20 sequestration (Schizosaccharomyces pombe)


name: (2S)-2-amino-4-deoxychorismate + H2O + L-glutamine <=> 4-amino-4-deoxychorismate + L-glutamate + NH4(+)


name: p-S225-SPHK1 localizes to cytosol (Mus musculus)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Saccharomyces cerevisiae)


name: AKR1B15 reduces EST17b to E1 (Schizosaccharomyces pombe)


name: 6-deoxo-28-nortyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 28-nortyphasterol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: GDP + glycolate + H(+) => H2O + N(2)-(1-hydroxy-2-oxoethyl)-GDP


name: CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Drosophila melanogaster)


name: 6-carboxyhexanoyl-CoA + NAD(+) = 6-carboxyhex-2-enoyl-CoA + H(+) + NADH


name: Translocation of p27 to the nucleoplasm (Rattus norvegicus)


name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Rattus norvegicus)


name: 2 L-ascorbate + N-decanoylglycine + O2 = H2O + 2 monodehydro-L-ascorbate radical + N-decanoyl-(2S)-hydroxyglycine


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Sus scrofa)


name: H2O + NADP(+) + penigequinolone B => H(+) + NADPH + yaequinolone D


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 = (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Bos taurus)


name: AKT1S1 (PRAS40) binds mTORC1 (Bos taurus)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H4] => acetyl-CoA + N-terminal L-seryl-[histone H4]


name: menaquinone-8 + sn-glycerol 3-phosphate <=> dihydroxyacetone phosphate + menaquinol-8


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)


name: CDK1 phosphorylates NUP98 (Drosophila melanogaster)


name: [thioredoxin]-dithiol + ADP => [thioredoxin]-disulfide + dADP + H2O


name: methyl tertiary butyl ether 3-monooxygenase activity


name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Homo sapiens)


name: CD28 homodimer binds B7-2 monomer (Rattus norvegicus)


name: acetate + N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine => H2O + N,N'-diacetylchitobiose


name: chloride(out) + L-cysteine(out) + 2 Na(+)(out) => chloride(in) + L-cysteine(in) + 2 Na(+)(in)


name: tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer (Homo sapiens)


name: BORA binds PLK1 and AURKA (Rattus norvegicus)


name: NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Bos taurus)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + AH2 + S-adenosyl-L-methionine = 5'-deoxyadenosine + 5-hydroxybenzimidazole + A + formate + 2 H(+) + L-methionine + NH4(+) + phosphate


name: Expression of STAT5 upregulated genes (Homo sapiens)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)


name: Formation of cap binding complex (CBC) (Dictyostelium discoideum)


name: 9alpha-hydroxy-3-oxochol-4-en-22-oate + H2O + NAD(+) => 3-oxochol-4-en-22-oate + H(+) + NADH + O2


name: cytoskeletal protein-membrane anchor activity


name: (E)-isoeugenol + acetate + NADP(+) <=> (E)-coniferyl acetate + NADPH


name: (3S,6E)-nerolidol + O2 + reduced [NADPH--hemoprotein reductase] <=> (3E)-4,8-dimethylnona-1,3,7-triene + but-3-en-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: GTP + 2 H2O = GMP + 2 H(+) + 2 phosphate


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + UDP


name: Cyclisation of GTP to precursor Z (Canis familiaris)


name: H2O + N-dodecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-dodecanoylethanolamine


name: H(+) + NADH + O2 + salicylate <=> 2,5-dihydroxybenzoate + H2O + NAD(+)


name: p-S207 KARS displaces HINT1 (Canis familiaris)


name: ATP + H(+) + salicylate = 2-hydroxybenzoyl-5'-AMP + diphosphate


name: ent-3beta-hydroxycassa-12,15-dien-2-one + 3 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => ent-cassa-12,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: NuRD complex binds SUMO2-6K-TRIM28:KRAB-ZNF:retroelement (Homo sapiens)


name: ATXN3 binds VCP (Caenorhabditis elegans)


name: WLS:WNT complex is internalized for maturation into exosomes (Drosophila melanogaster)


name: (E)-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA => (E)-pinosylvin + 4 CO2 + 4 CoA


name: (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + diphosphate => (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + dimethylallyl diphosphate


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Sus scrofa)


name: Caspase-mediated cleavage of gelsolin (Caenorhabditis elegans)


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + vanillate => 3,4-dihydroxybenzoate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: NADPH + O2 + trimethylamine <=> H2O + NADP(+) + trimethylamine N-oxide


name: (2E,6E)-farnesyl diphosphate => (+)-amorpha-4,11-diene + diphosphate


name: L-galactonate => 2-dehydro-3-deoxy-L-galactonate + H2O


name: [protein]-with a C-terminal TM segment(out) + ATP + H2O => [protein]-with a C-terminal TM segment(in) + ADP + H(+) + phosphate


name: alpha,beta-didehydrotryptophan + H2O2 => L-tryptophan + O2


name: 3-(2,4-dioxopentyl)-2,3,6,8,9-pentahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] <=> 2-acetyl-3,4a,8,10,11,12a-hexahydroxy-1,4,4a,5,12,12a-hexahydrotetracene-1,12-dione + H(+) + holo-[ACP]


name: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O2 => 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Canis familiaris)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Mus musculus)


name: histidine => urocanate + NH4+ (Homo sapiens)


name: 6,8-dimethyl-6,7-didehydroergoline + H2O => dihydrochanoclavine-I aldehyde


name: Formation of P-TEFb complex (Bos taurus)


name: PTK6 phosphorylates ARHGAP35 (Xenopus tropicalis)


name: CNTF binds CNTFR complex (Rattus norvegicus)


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Danio rerio)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Homo sapiens)


name: 3-hydroxypropanoate + ATP + CoA = 3-hydroxypropanoyl-CoA + AMP + diphosphate


name: Dissociation of the COP1-p53 complex (Mus musculus)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Sus scrofa)


name: GUCY2C trimer binds GUCA2A,B (Homo sapiens)


name: dimethylamine + formaldehyde + reduced [electron-transfer flavoprotein] => H(+) + H2O + oxidized [electron-transfer flavoprotein] + trimethylamine


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + CoA => 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA


name: 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA => 2-methylhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: RAC2 GDIs block activation of RAC2 (Danio rerio)


name: AMY1-3 bind IAPP(34-70) (Canis familiaris)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Homo sapiens)


name: lipoxin A4 + NAD(+) <=> 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H(+) + NADH


name: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + 2 H(+) => 3,4,5-trihydroxybenzoate + O2


name: (2Z,6Z)-farnesyl diphosphate = beta-acoradiene + diphosphate


name: ATP + L-histidyl-[protein] <=> ADP + H(+) + N(pros)-phospho-L-histidyl-[protein]


name: NADP(+) + taurochenodeoxycholate => 7-oxotaurolithocholate + H(+) + NADPH


name: SUMOylation of HIPK2 with SUMO1 (Caenorhabditis elegans)


name: a 3beta-hydroxy-Delta(5)-steroid + NADP(+) => a 3-oxo-Delta(5)-steroid + H(+) + NADPH


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Homo sapiens)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Schizosaccharomyces pombe)


name: CDK and DDK associate with the Mcm10:pre-replicative complex (Sus scrofa)


name: CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 (Mus musculus)


name: (2R,3R)-dihydroquercetin + H(+) + NADH + O2 = (2R,3R)-2,3-dihydrogossypetin + H2O + NAD(+)


name: a primary amine + S-adenosyl-L-methionine => a methylated primary amine + H(+) + S-adenosyl-L-homocysteine


name: acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18]


name: MMP14 (MT1-MMP) binds TIMP2 (Homo sapiens)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Bos taurus)


name: 2'-deoxyuridine + NH4(+) => 2'-deoxycytidine + H(+) + H2O


name: 2-methylpropanenitrile + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylpropanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate = diphosphate + silphinene


name: 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine <=> anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Schizosaccharomyces pombe)


name: inositol phosphorylceramide synthase activity


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Mus musculus)


name: Release of E3 from polyubiquitinated substrate (Dictyostelium discoideum)


name: (3R)-3-isocyanylbutanoate + ATP + H(+) => (3R)-3-isocyanylbutanoyl-AMP + diphosphate


name: 2-oxoglutarate + a (3R)-3-{[carboxy(hydroxy)methyl]amino}fatty acid + O2 = a (3R)-3-isocyanyl-fatty acid + 2 CO2 + 2 H2O + succinate


name: Association of procollagen type XXIII (Bos taurus)


name: CHRM4 binds CHRM4 antagonists (Sus scrofa)


name: ADP + alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A


name: PITPNM1,2,3 exchange PI for PA (Schizosaccharomyces pombe)


name: CTP(out) + dCTP(in) = CTP(in) + dCTP(out)


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Canis familiaris)


name: a medium-chain (3R)-hydroxyacyl-CoA + NAD(+) => a medium-chain 3-oxoacyl-CoA + H(+) + NADH


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate => 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate


name: a primary linear alkyl sulfate ester + H2O <=> a primary alcohol + H(+) + sulfate


name: a fatty acid + L-serine => an N-(fatty acyl)-L-serine + H2O


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Bos taurus)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Canis familiaris)


name: SEPHS2 phosphorylates H2Se to form SELP (Homo sapiens)


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Homo sapiens)


name: CHOL translocates from lysosome membrane to ER membrane (Sus scrofa)


name: TP53 stimulates ARID3A gene expression (Homo sapiens)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Canis familiaris)


name: AMP + decanoyl-[ACP] + H(+) => decanoyl-AMP + holo-[ACP]


name: alpha,alpha-trehalose + phosphate <=> alpha-D-glucose + alpha-D-glucose 1-phosphate


name: Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)


name: 12-hydroxydodecanoate + NAD(+) <=> 12-oxododecanoate + H(+) + NADH


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Primary piRNA transcript translocates from nucleoplasm to cytosol (Homo sapiens)


name: H(+) + NADH + O2 + toluene => 2-hydroxytoluene + H2O + NAD(+)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPC (Xenopus tropicalis)


name: L-seryl-[protein] + UTP <=> diphosphate + uridylyl-L-seryl-[protein]


name: Defective mitochondrial BTD does not hydrolyse BCTN (Homo sapiens)


name: Interaction of Tie2 and Shp2 (Xenopus tropicalis)


name: MDM2 ubiquitinates TP53 (Canis familiaris)


name: HYAL1 hydrolyses Chondroitin chains (Mus musculus)


name: SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Bos taurus)


name: (2E)-3-methyl-5-phosphooxypent-2-enoate + H(+) => CO2 + isopentenyl phosphate


name: Viral dsRNA:TLR3 recruits TRIF (TICAM1) (Homo sapiens)


name: geranylgeranyl diphosphate <=> beta-araneosene + diphosphate


name: L-serine + phosphate => H2O + O-phospho-L-serine


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Schizosaccharomyces pombe)


name: NSF and SNAPs bind cis-SNARE complex (Caenorhabditis elegans)


name: 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O => (9Z)-octadecenoate + 1',3'-bis-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H(+)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Danio rerio)


name: JLP interacts with CDO complex (Homo sapiens)


name: Transhomodimerization of Nectins (Mus musculus)


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Sus scrofa)


name: ATM phosphorylates RBBP8 (Schizosaccharomyces pombe)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Rattus norvegicus)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Rattus norvegicus)


name: Phosphorylation of CRMPs by Cdk5 (Bos taurus)


name: 1-O-(9Z,12Z)-octadecadienylglycerone 3-phosphate + H(+) + hexadecanoate => (9Z,12Z)-octadecadien-1-ol + 1-hexadecanoylglycerone 3-phosphate


name: I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + 10-hydroperoxy-(8E)-octadecenoate + H(+)


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Drosophila melanogaster)


name: a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH


name: glycerol-3-phosphate transmembrane transporter activity