name: Dimerization of PERK (Rattus norvegicus)


name: Raf dimer inhibitors bind RAF heterodimers (Sus scrofa)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Canis familiaris)


name: (S)-lactate + 2 H(+) + NADH => (S)-lactaldehyde + H2O + NAD(+)


name: Methylthio-ribulose-P = Methylthio-ribose-P (Bos taurus)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Caenorhabditis elegans)


name: (8S)-8-amino-7-oxononanoate + CO2 + L-lysyl-[protein] => (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 2 H(+)


name: Alpha-1-Microglobulin is cleaved (Canis familiaris)


name: 23,24-dihydrocucurbitacin B + NAD(+) <=> cucurbitacin B + H(+) + NADH


name: CRLF1:IL27 translocates to the extracellular region (Bos taurus)


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Mus musculus)


name: ADP + H(+) + N-phosphocreatine => ATP + creatine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CDP + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CTP


name: CDK5:p25 phosphorylates JUN (Homo sapiens)


name: S-adenosyl-L-methionine + syringetin => 7,3',5'-O-trimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: fumarate + menaquinol-8 <=> menaquinone-8 + succinate


name: p-STAT5A/B dissociates from the Growth Hormone receptor (Gallus gallus)


name: 2-acyl LPG is acylated to PG by LPGAT (Danio rerio)


name: Association of RAD51 with BRCA1 (Gallus gallus)


name: Factor I inactivates plasma Factor H-bound C3b (Xenopus tropicalis)


name: a menaquinol(in) + dimethyl sulfoxide(out) => a menaquinone(in) + dimethyl sulfide(out) + H2O(out)


name: (11R)-carlactone + O2 + reduced [NADPH--hemoprotein reductase] => (11R)-19-hydroxycarlactone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p85 regulatory unit of PI3K binds p-6Y-SYK (Gallus gallus)


name: 6-oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O = 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)


name: MAPKAPK5 phosphorylates TP53 (Sus scrofa)


name: Mitochondrial recruitment of Drp1 (Mus musculus)


name: Extracellular KSPG translocates to the lysosome for degradation (Bos taurus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: PA is hydrolyzed to 1-acyl LPA by PLA2[15] (Caenorhabditis elegans)


name: a long-chain fatty acyl-AMP + holo-[ACP] = a long-chain fatty acyl-[ACP] + AMP + H(+)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine = H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + sn-glycerol 3-phosphate


name: Autoglucosylation of GYG2 complexed with GYS2-a (Homo sapiens)


name: ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (Bos taurus)


name: cholest-4-en-3-one + H(+) + NADPH => 5beta-cholestan-3-one + NADP(+)


name: DNA nucleases bind monoubiquitinated ID2 complex (Rattus norvegicus)


name: 5,6-diaminouracil + D-ribose 5-phosphate => 5-amino-6-(5-phospho-D-ribosylamino)uracil + H2O


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + H(+) + phosphate


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Caenorhabditis elegans)


name: H(+) + raucaffricine + UDP => UDP-alpha-D-glucose + vomilenine


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Sus scrofa)


name: LFT binds to FT and DS (Drosophila melanogaster)


name: CYP2S1 4-hydroxylates atRA (Dictyostelium discoideum)


name: AKT binds PDPK1 (Caenorhabditis elegans)


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADPH => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+)


name: 2 H(+)(out) + L-alanyl-L-alanine(out) <=> 2 H(+)(in) + L-alanyl-L-alanine(in)


name: Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants (Homo sapiens)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Drosophila melanogaster)


name: a chlorophyll + H2O = a chlorophyllide + H(+) + phytol


name: DHFR dimer reduces FOLA to DHF (Schizosaccharomyces pombe)


name: a sterol + UDP-alpha-D-glucose <=> a sterol 3-beta-D-glucoside + H(+) + UDP


name: 1,2,3-tri-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+)


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Mus musculus)


name: Myosin phosphatase dephosphorylates PLK1 (Danio rerio)


name: FRS2 binds to active TrkA receptor (Bos taurus)


name: BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Caenorhabditis elegans)


name: Activated FGFR2 phosphorylates FRS3 (Canis familiaris)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: SUMOylation of TOP1 with SUMO1 (Saccharomyces cerevisiae)


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Bos taurus)


name: RAC2 translocates to the mitochondrial membrane (Canis familiaris)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Rattus norvegicus)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Danio rerio)


name: p190RhoGAP binds Plexin-B1 (Gallus gallus)


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Mus musculus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Dictyostelium discoideum)


name: IMPDH tetramers binds IMPDH inhibitors (Saccharomyces cerevisiae)


name: FAHD1 dimer hydrolyses OA to PYR (Rattus norvegicus)


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Rattus norvegicus)


name: S-adenosyl-L-methionine + tricetin <=> 3'-O-methyltricetin + H(+) + S-adenosyl-L-homocysteine


name: 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: candesartan + UDP-alpha-D-glucuronate = candesartan-2-N-beta-D-glucuronide + UDP


name: proton-transporting ATPase activity, rotational mechanism


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Homo sapiens)


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Mus musculus)


name: 13-cis-retinal + H(+) + NADH => 13-cis-retinol + NAD(+)


name: IL17RD binds p-2S MAP2Ks and MAPKs (Homo sapiens)


name: p75NTR and RHOA-GDI interact (Gallus gallus)


name: a quinone + H2O + L-methionyl-[protein] => a quinol + L-methionyl-(S)-S-oxide-[protein]


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Gallus gallus)


name: SMPD4 hydrolyzes sphingomyelin (ER membrane) (Homo sapiens)


name: Phosphorylation of cohesin by PLK1 at centromeres (Rattus norvegicus)


name: Arachidonic acid is oxidised to PGG2 by PTGS1 (Sus scrofa)


name: 2-carboxy-L-lyxonolactone + H2O <=> 2-carboxy-L-lyxonate + H(+)


name: (2R,3S)-2,3-dimethylmalate => dimethylmaleate + H2O


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Sus scrofa)


name: H2O + N-ethylglycine + O2 <=> ethylamine + glyoxylate + H2O2


name: 2 putrescine = NH4(+) + sym-homospermidine


name: ATP + streptomycin <=> 6-O-adenylylstreptomycin + diphosphate


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O = a 5'-end phospho-guanosine in mRNA + 2 H(+) + N(7)-methyl-GDP


name: alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose <=> alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose


name: SCF-FBXL7 ubiquitinates AURKA (Canis familiaris)


name: AJUBA binds centrosome-associated AURKA (Sus scrofa)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Rattus norvegicus)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Caenorhabditis elegans)


name: glycine betaine + 2 H(+) + NADPH => betaine aldehyde + H2O + NADP(+)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Sus scrofa)


name: 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) <=> 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: CO binds to Cytochrome c oxidase (Danio rerio)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Drosophila melanogaster)


name: spermine monoaldehyde => acrolein + spermidine


name: p-MAPK2/3 phosphorylates HSP27 (Sus scrofa)


name: a 5-formyl-2'-deoxycytidine in DNA + CO2 + H2O + succinate => 2-oxoglutarate + a 5-hydroxymethyl-2'-deoxycytidine in DNA + O2


name: Cleavage of C5 by C5 convertases (Gallus gallus)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Plasmodium falciparum)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: (6S)-NADPHX + ADP => AMP + H(+) + NADPH + phosphate


name: SAMD8 transfers phosphatidyl from PE onto C16DH CER (Plasmodium falciparum)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Canis familiaris)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Caenorhabditis elegans)


name: (2E,4E,6E)-octa-2,4,6-trienyl-[ACP] + AH2 + 3 H(+) + 4 malonyl-CoA => 2,4-dihydroxy-6-[(3E,5E,7E)-2-oxonona-3,5,7-trienyl]benzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP]


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (15S)-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate


name: HLCS biotinylates PC:Mn2+ (Xenopus tropicalis)


name: Activation of Ca-permeable Kainate receptors (Gallus gallus)


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + guaiacol + H(+) <=> catechol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine = H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine


name: an alpha-D-glucuronoside + H2O <=> an alcohol + D-glucuronate


name: AMY1-3 bind pramlintide (Canis familiaris)


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Bos taurus)


name: Recruitment of CBL to KIT (Caenorhabditis elegans)


name: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity


name: Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex (Homo sapiens)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Dictyostelium discoideum)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Dictyostelium discoideum)


name: E2F6 binds the PRC1 complex (Mus musculus)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+) => 1-O-alkyl-2-acyl-sn-glycerol + ATP


name: 8-carboxy-8-demethylriboflavin 5'-phosphate + 2 A + H2O + L-glutamate = 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 2 AH2 + CO2


name: ATM phosphorylates TP53 at S15 (Drosophila melanogaster)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Drosophila melanogaster)


name: (S)-miconazole(in) + ATP + H2O <=> (S)-miconazole(out) + ADP + H(+) + phosphate


name: H2O + N-acetyl-D-galactosamine + O2 = H(+) + H2O2 + N-acetyl-D-galactosaminate


name: RhoGTPase GEF's recruited to DCC (Rattus norvegicus)


name: 3-hydroxy-2,4-dioxopentyl phosphate + CoA => acetyl-CoA + dihydroxyacetone phosphate


name: (2E)-decenoyl-CoA + H(+) + oxaloacetate <=> (4-octa-1-enyl-2,5-dioxo-2,5-dihydro-3-furanyl)acetate + CoA + H2O


name: H(+)(out) + 2 nitrate(out) => H(+)(in) + 2 nitrate(in)


name: Beta-catenin recruits CBP/p300 (Rattus norvegicus)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA <=> (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: cholate + L-serine = H2O + L-serocholate


name: Free APC/C phosphorylated by Plk1 (Sus scrofa)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Homo sapiens)


name: 1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol


name: beta-alanyl-dopamine + H2O = beta-alanine + dopamine


name: Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Homo sapiens)


name: (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Furin cleaves pro-factor X to factor X (Bos taurus)


name: cholate + L-arginine <=> H2O + L-arginocholate


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Danio rerio)


name: dTDP-alpha-D-forosamine + H(+) + S-adenosyl-L-homocysteine => dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine


name: MHC class Ib protein binding, via lateral surface


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Bos taurus)


name: 8-oxo-dGMP + diphosphate + H(+) => 8-oxo-dGTP + H2O


name: CEBPA binds CDKN1A (p21) (Gallus gallus)


name: Activated FGFR2 binds SHC1 (Drosophila melanogaster)


name: Interaction of p38 MAPK with JLP (Homo sapiens)


name: SOX10 binds CDH19 gene promoter (Homo sapiens)


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Bos taurus)


name: 2 H(+) + 3 H2O + hydrogen sulfide + 3 oxidized coenzyme F420-(gamma-L-Glu)(n) <=> 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Xenopus tropicalis)


name: chloride + FADH2 + L-tryptophan + O2 <=> 5-chloro-L-tryptophan + FAD + 2 H2O


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-leucine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-leucine


name: 5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) (Gallus gallus)


name: (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Mus musculus)


name: 5,6-dihydrouridine(20a) in tRNA + NADP(+) => H(+) + NADPH + uridine(20a) in tRNA


name: L-tryptophan(in) + Na(+)(in) => L-tryptophan(out) + Na(+)(out)


name: 3'-phosphoadenylyl sulfate + quercetin 3-sulfate => adenosine 3',5'-bisphosphate + H(+) + quercetin 3,3'-bissulfate


name: GGCT transforms gGluCys to OPRO (Rattus norvegicus)


name: Defective OPN1LW causes CBP (Homo sapiens)


name: [(1->4)-3,6-bisphospho-alpha-D-glucosyl](n) + n AMP + 2n H(+) + n phosphate => [(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O


name: ROCK activation by RHO (Rattus norvegicus)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + (E)-4-coumaroyl-CoA => (E)-4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA


name: SLC22A1 transports Cipro into renal cell (Caenorhabditis elegans)


name: 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + 6 CO2 + 7 CoA + H2O => acetyl-CoA + 5 H(+) + 6 malonyl-CoA


name: p-S158,221-HuR binds mRNA (Gallus gallus)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Bos taurus)


name: NFE2L2-dependent PGD gene expression (Homo sapiens)


name: a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GD1a + CMP + H(+)


name: 2-oxoglutarate + 3-hydroxy-L-kynurenine = 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-glutamate


name: IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 (Sus scrofa)


name: Disassembly of tight junctions (Bos taurus)


name: USP33 deubiquitinates CCP110,ARRB (Sus scrofa)


name: H2O + isomaltose => beta-D-glucose + D-glucose


name: (3Z,5E)-dodecadienoate + CoA + H(+) => (3Z,5E)-dodecadienoyl-CoA + H2O


name: 5beta-androstane-3,17-dione + H(+) + NADPH = 3beta-hydroxy-5beta-androstane-17-one + NADP(+)


name: PEX19:class I PMP binds PEX3 (Xenopus tropicalis)


name: O2 + quercetin => 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Caenorhabditis elegans)


name: L-aspartate(out) + L-tyrosine(in) => L-aspartate(in) + L-tyrosine(out)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Homo sapiens)


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Rattus norvegicus)


name: citrate(out) + fumarate(in) <=> citrate(in) + fumarate(out)


name: DLST transfers succinyl to CoA (Bos taurus)


name: Proteasomal cleavage of substrate (Rattus norvegicus)


name: an aromatic oxo-acid + L-glutamate => 2-oxoglutarate + an aromatic L-alpha-amino acid


name: a very-long-chain 3-oxoacyl-CoA + CO2 + CoA => a very-long-chain acyl-CoA + H(+) + malonyl-CoA


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Bos taurus)


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Canis familiaris)


name: The receptor is activated (Gallus gallus)


name: ATP + H2O + L-ectoine(out) <=> ADP + H(+) + L-ectoine(in) + phosphate


name: PKA phosphorylates GLI3 (Drosophila melanogaster)


name: ROS oxidize FOXO4 cysteine residues (Homo sapiens)


name: CDK4 inhibitors bind CDK4 (Canis familiaris)


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Rattus norvegicus)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Bos taurus)


name: (3R)-3-isocyanylbutanoyl-AMP + holo-[ACP] => (3R)-3-isocyanylbutanoyl-[ACP] + AMP + H(+)


name: cytidine(48) in tRNA precursor + S-adenosyl-L-methionine <=> 5-methylcytidine(48) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: ULK complex translocates to the ER (Mus musculus)


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Rattus norvegicus)


name: arginine + H2O => ornithine + urea (Gallus gallus)


name: diphosphate + isoechinulin B => dimethylallyl diphosphate + neoechinulin B


name: odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Canis familiaris)


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Canis familiaris)


name: Autophosphorylation of PDGF alpha/beta receptors (Xenopus tropicalis)


name: a 5'-end diphospho-adenosine in mRNA + H(+) + phosphate => a 5'-end triphospho-adenosine in mRNA + H2O


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Danio rerio)


name: dihydrochelirubine + O2 + reduced [NADPH--hemoprotein reductase] = 12-hydroxydihydrochelirubine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5-dehydroepisterol + 2 H2O + NADP(+) => episterol + H(+) + NADPH + O2


name: glyoxylate + L-alanine => glycine + pyruvate


name: guanosine(in) + Na(+)(in) => guanosine(out) + Na(+)(out)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Caenorhabditis elegans)


name: Guanine + H2O => Xanthine + NH4+ (Sus scrofa)


name: a D-5-monosubstituted hydantoin = a L-5-monosubstituted hydantoin


name: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+)


name: Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + O2 = CO2 + formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + succinate


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-glycerol + phosphate


name: H(+) + menaquinol-10 + S-adenosyl-L-homocysteine => 2-demethylmenaquinol-10 + S-adenosyl-L-methionine


name: Initial activation of proMMP13 by plasmin and trypsin (Sus scrofa)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine + ethanolamine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + L-serine


name: Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA (Homo sapiens)


name: an aliphatic alcohol + H(+) + hexadecanoate => H2O + hexadecanoate ester


name: 5,6-dihydrouridine(17) in tRNA + NADP(+) <=> H(+) + NADPH + uridine(17) in tRNA


name: (2E,4E)-hexadienoyl-CoA + H(+) + NADPH <=> (3E)-hexenoyl-CoA + NADP(+)


name: H2O + trihexanoylglycerol => 2,3-dihexanoyl-sn-glycerol + H(+) + hexanoate


name: FGAM + ATP => AIR + ADP + Pi (Bos taurus)


name: DERA cleaves dR5P to GA3P and CH3CHO (Bos taurus)


name: (2E,13Z)-eicosadienoyl-CoA + H2O => (R)-3-hydroxy-(13Z)-eicosenoyl-CoA


name: TIFA oligomerization (Rattus norvegicus)


name: PLC beta-mediated PIP2 hydrolysis (Gallus gallus)


name: 2-phenylacetaldehyde + H2O2 + NH4(+) => 2-phenylethylamine + H2O + O2


name: Autoubiquitination of phospho-COP1(Ser-387 ) (Bos taurus)


name: p-S225-SPHK1 localizes to cytosol (Bos taurus)


name: Endocytosis of Ca impermeable AMPA receptors (Sus scrofa)


name: C1-Inh binds and inactivates C1r, C1s (Bos taurus)


name: Inactivation of LCK by PTPN22 (Canis familiaris)


name: ST6GALNAC5,6 transfer Neu5Ac to GM1b (Sus scrofa)


name: S-(hydroxymethyl)glutathione dehydrogenase (NAD(P)+) activity


name: TRPA1 tetramer binds TRPA1 antagonists (Danio rerio)


name: FRAT proteins bind GSK3beta (Rattus norvegicus)


name: 2 L-ascorbate + N-dodecanoylglycine + O2 <=> H2O + 2 monodehydro-L-ascorbate radical + N-dodecanoyl-(2S)-hydroxyglycine


name: [(1->4)-beta-D-glucosyl](n+1) + H(+) + UDP => [(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose


name: β1,2-agonists bind ADRB1,2 (Gallus gallus)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Rattus norvegicus)


name: ILK interacts with beta-1 integrin (Sus scrofa)


name: SUMOyation of DNMT1 with SUMO1 (Rattus norvegicus)


name: H2O + L-methionyl-tRNA(Leu) <=> H(+) + L-methionine + tRNA(Leu)


name: 1,6-dihydroxyphenazine + S-adenosyl-L-methionine <=> 1-hydroxy-6-methoxyphenazine + H(+) + S-adenosyl-L-homocysteine


name: P2Y10 receptor can bind to LPA (Danio rerio)


name: MSH2 variant:MSH3-defective DNA mismatch repair (Homo sapiens)


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Caenorhabditis elegans)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O <=> 2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + hexadecanoate


name: p-SLP-76 binds ADAP (Xenopus tropicalis)


name: (R)-4'-phosphopantetheine + CO2 => H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine


name: GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate + H2O => diphosphate + tau-cadinol


name: PLK1 phosphorylates FOXM1 (Canis familiaris)


name: butanoyl-CoA + H(+) + malonyl-[ACP] <=> 3-oxohexanoyl-[ACP] + CO2 + CoA


name: RSF complex binds the centromere (Mus musculus)


name: CYP8B1 12-hydroxylates 4CHOL7a,27DONE (Mus musculus)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Xenopus tropicalis)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O


name: p62:MEKK3 binds to TRAF6 (Gallus gallus)


name: mannitol transmembrane transporter activity


name: protein-glycine ligase activity, elongating


name: MyD88 interacts with the activated TLR receptor 7, 8 or 9  (Homo sapiens)


name: ATP + N-acetyl-D-muramate <=> ADP + H(+) + N-acetyl-alpha-D-muramate 1-phosphate


name: H2O2 + N-acetyl-D-galactosamino-1,5-lactone => N-acetyl-D-galactosamine + O2


name: Exocytosis of platelet dense granule content (Drosophila melanogaster)


name: all-trans-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: 5-N(alpha)-glycyl-dTMP in DNA + AH2 + S-adenosyl-L-methionine = 5'-deoxyadenosine + 5-C(alpha)-glycyl-dTMP in DNA + A + H(+) + L-methionine


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Caenorhabditis elegans)


name: guanosine(34) in tRNA + queuine = guanine + queuosine(34) in tRNA


name: REL binds to DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)


name: p-PKR dimer phosphorylates SPHK1 (Gallus gallus)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Sus scrofa)


name: 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + H2O <=> 5'-triphosphoadenylyl-(2'->5')-adenosine + AMP + H(+)


name: Phosphorylation of YAP by LATS1 (Homo sapiens)


name: N-atom dealkylation of caffeine (Mus musculus)


name: glycine + L-arginocholate => glycocholate + L-arginine


name: Fusion of late-endosome derived vesicles at the TGN (Canis familiaris)


name: Phosphorylation (Ser5) of RNA pol II CTD (Xenopus tropicalis)


name: 1-deoxysphinganine + a fatty acyl-CoA => CoA + H(+) + N-acyl-1-deoxysphinganine


name: H(+)(out) + L-glutamate(out) => H(+)(in) + L-glutamate(in)


name: Endocytosis of TRAM (TICAM2) (Rattus norvegicus)


name: Dopamine is oxidised to noradrenaline (Danio rerio)


name: Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 (Danio rerio)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Mus musculus)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose <=> a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + H(+) + UDP


name: 9beta-pimara-7,15-dien-19-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> 9beta-pimara-7,15-dien-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NADP(+) + reduced riboflavin => 2 H(+) + NADPH + riboflavin


name: Loading of antigenic peptides on to class I MHC (Mus musculus)


name: CYP1A2 hydroxylates AFB1 to AFM1 (Danio rerio)


name: Phosphorylation of GAB2 by SFKs (Mus musculus)


name: PKR binds activating host RNA (Drosophila melanogaster)


name: 2 L-ascorbate + O2 = 2 H2O + 2 L-dehydroascorbate


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Schizosaccharomyces pombe)


name: H2O + tuberculosinyl diphosphate => (13S)-edaxadiene + diphosphate


name: Autophosphorylation of PKC-theta (Drosophila melanogaster)


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Rattus norvegicus)


name: (S)-coclaurine + S-adenosyl-L-methionine <=> (S)-N-methylcoclaurine + H(+) + S-adenosyl-L-homocysteine


name: [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA = [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl](n) + n CoA


name: Mcm4,6,7 trimer forms and associates with the replication fork (Saccharomyces cerevisiae)


name: 3-(2,3-dihydroxyphenyl)propanoate + O2 = (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate + H(+)


name: Secreted CD14 binds LPS (Canis familiaris)


name: loading of Serotonin in synaptic vesicles (Schizosaccharomyces pombe)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+) => 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP


name: "[heparan sulfate]-glucosamine 3-sulfotransferase 1"


name: Active calmodulin binds CAMK2 (Drosophila melanogaster)


name: ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Rattus norvegicus)


name: Monoubiquitination of FANCD2:FANCI (Rattus norvegicus)


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphinganine + H2O <=> beta-D-glucose + N-hexadecanoylsphinganine


name: H2O + pristanoyl-CoA = 2,6,10,14-tetramethylpentadecanoate + CoA + H(+)


name: alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+) => GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate


name: RAP1A exchanges GDP for GTP (Saccharomyces cerevisiae)


name: factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain (Canis familiaris)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Caenorhabditis elegans)


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Schizosaccharomyces pombe)


name: 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O <=> (9Z)-octadecenoate + 1',3'-bis-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H(+)


name: 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + progesterone + reduced [NADPH--hemoprotein reductase]


name: Receptor FFAR3 binds carboxylates (Mus musculus)


name: Expression of ANGPTL3 regulated by NR1H2 or NR1H3 (Homo sapiens)


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Drosophila melanogaster)


name: 15alpha-stemmadenine intermediate II + NADP(+) = 15alpha-stemmadenine intermediate I + NADPH


name: 3-hydroxy-3-methylglutarate + succinyl-CoA => (3S)-hydroxy-3-methylglutaryl-CoA + succinate


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Danio rerio)


name: Tetramerization of procollagen VI (Sus scrofa)


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: EDA:EDAR binds EDARADD (Rattus norvegicus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Rattus norvegicus)


name: prostaglandin E2 <=> H2O + prostaglandin A2


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Schizosaccharomyces pombe)


name: ATP + xylitol = ADP + H(+) + xylitol 5-phosphate


name: 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine => adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Homo sapiens)


name: Interleukin-35 translocates from the ER lumen to the extracellular region (Mus musculus)


name: nocamycin E + S-adenosyl-L-methionine <=> nocamycin I + S-adenosyl-L-homocysteine


name: Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD+PEST domain mutants (Homo sapiens)


name: chloride(out) + oxalate(in) <=> chloride(in) + oxalate(out)


name: H2O + N(tele)-phospho-L-histidyl-[protein] => L-histidyl-[protein] + phosphate


name: RNASEL cleaves cellular ssRNA (Mus musculus)


name: cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Gallus gallus)


name: pseudouridine(35) in tRNA(Tyr) => uridine(35) in tRNA(Tyr)


name: a short-chain 3-oxoacyl-CoA + H(+) + NADH => a short-chain (3S)-3-hydroxyacyl-CoA + NAD(+)


name: carbaryl + H(+) + H2O => 1-naphthol + CO2 + methylamine


name: LGALS3 gene expression is stimulated by RUNX1 and RUNX2 (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2 H2O => 2 H(+) + 2 hexadecanoate + sn-glycerol 3-phosphocholine


name: SOX17 and TFAP2C bind the PRDM1 gene (Homo sapiens)


name: MDM2 homodimers auto-ubiquitinate (Bos taurus)


name: SRC family kinases phosphorylate ERBB2 (Canis familiaris)


name: VENTX binds the IL6 gene promoter (Homo sapiens)


name: FN3KRP phosphorylates PsiAm, RibAm (Gallus gallus)


name: Excess cysteine yields lanthionine and H2S (Schizosaccharomyces pombe)


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Dictyostelium discoideum)


name: Tropoelastin forms aggregate globules (Homo sapiens)


name: CSNK2-mediated phosphorylation of DVL (Mus musculus)


name: GLUT7 and GLUT11 transport glucose and fructose (Rattus norvegicus)


name: a 1,3-diacyl-sn-glycerol + H2O => a fatty acid + a monoacylglycerol + H(+)


name: 8'-apo-beta-carotenol + O2 => (3E,5E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal


name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) <=> 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH


name: 4-hydroxy-3-all-trans-decaprenylbenzoate + H(+) <=> 2-all-trans-decaprenylphenol + CO2


name: 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA => 16-hydroxyhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: Cho is acetylated to AcCho by CHAT (Bos taurus)


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Caenorhabditis elegans)


name: carnosine(in) + 2 H(+)(in) => carnosine(out) + 2 H(+)(out)


name: [(2->1)-beta-D-fructosyl](n) + sucrose => [(2->1)-beta-D-fructosyl](n+1) + D-glucose


name: PSGs bind proteoglycans and TGF-beta1 (Xenopus tropicalis)


name: PKR binds activating host RNA (Homo sapiens)


name: (3R)-hydroxy-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA = (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H2O


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Drosophila melanogaster)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Gallus gallus)


name: PLK1 phosphorylates NUDC (Gallus gallus)


name: 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoserine + CoA => (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Bos taurus)


name: ATP + sedoheptulose = ADP + D-sedoheptulose 7-phosphate + H(+)


name: 2xENPP1 hydrolyzes FAD to FMN (Xenopus tropicalis)


name: Association of Nek2A with MCC:APC/C (Gallus gallus)


name: Cleavage of Procaspase‑9 to caspase‑9 (Sus scrofa)


name: 2-acyl LPS is acylated to PS by LPSAT (Drosophila melanogaster)


name: CoA + H(+) + N-hexacosanoyl-eicosan-(4R)-hydroxysphinganine => (4R)-hydroxyeicosasphinganine + hexacosanoyl-CoA


name: gastrin-releasing peptide receptor binding


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Danio rerio)


name: ACSM2B-like proteins transform ST to ST-CoA (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 2 H(+) + 2 NADPH <=> (9Z)-octadecen-1-ol + CoA + 2 NADP(+)


name: F protein binds NCL on host cell surface (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + di-(9Z)-octadecenoylglycerol


name: a 2-acyl-sn-glycerol 3-phosphate + CoA => an acyl-CoA + sn-glycerol 3-phosphate


name: SYK binds to p-Y65,Y76-FCER1G (Bos taurus)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Danio rerio)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 A = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 AH2


name: oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: chloride(in) + 2 hydrogencarbonate(out) => chloride(out) + 2 hydrogencarbonate(in)


name: IMP + NADP(+) + NH4(+) = GMP + 2 H(+) + NADPH


name: RAC2 binds effectors at the mitochondrial outer membrane (Mus musculus)


name: a 1-[(17Z)-hexacos-17-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-hexacosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 5-formimidoyltetrahydrofolate + 2 H(+) <=> (6R)-5,10-methenyltetrahydrofolate + NH4(+)


name: Elastin degradation by MMP14 (Gallus gallus)


name: RUNX3 binds TEADs and YAP1 (Mus musculus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine


name: AH2 + ATP + 2 Co(II)-[methylamine-specific corrinoid protein] + H2O <=> A + ADP + 2 Co(I)-[methylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: Caveolin-1 binds Basigin (Canis familiaris)


name: n 3'-phosphoadenylyl sulfate + dermatan => n adenosine 3',5'-bisphosphate + dermatan 4'-sulfate + n H(+)


name: ISGylation of DDX58 (Plasmodium falciparum)


name: ATP + thiamine phosphate <=> ADP + thiamine diphosphate


name: pyridoxamine 5'-phosphate + pyruvate => L-alanine + pyridoxal 5'-phosphate


name: Activation of TWIK-related K+ channel (TREK) (Homo sapiens)


name: ATP + CoA + docosanoate => AMP + diphosphate + docosanoyl-CoA


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)


name: benzylamine + formate => H2O + N-benzylformamide


name: L-aspartate(out) + L-tryptophan(in) => L-aspartate(in) + L-tryptophan(out)


name: OSM binds LIFR:JAKs,OSMR:JAKs (Homo sapiens)


name: Secreted CD14 binds LPS (Rattus norvegicus)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Sus scrofa)


name: N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine => N-[omega-(9Z,12Z)-octadecadienoyloxy]-acylsphin-4-enine + O2


name: (3S)-hydroxytetradecanedioyl-CoA + NAD(+) <=> 3-oxotetradecanedioyl-CoA + H(+) + NADH


name: Dimerized phospho-IRF3 migrates to the nucleus (Homo sapiens)


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Caenorhabditis elegans)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Bos taurus)


name: methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity


name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol (Caenorhabditis elegans)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 8-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Mus musculus)


name: FUT2 transfers Fuc to LeA to form LeB (Xenopus tropicalis)


name: thromboxane B2(in) => thromboxane B2(out)


name: H2O + N,N-dimethylglycine + O2 => formaldehyde + H2O2 + sarcosine


name: Liganded Gz-activating GPCR acts as a GEF for Gz (Drosophila melanogaster)


name: HCAR2 binds HCAR2 ligands (Mus musculus)


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Homo sapiens)


name: PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Bos taurus)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Xenopus tropicalis)


name: a 2'-deoxycytidine in single-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in single-stranded DNA + O2


name: p75NTR and RHOA-GDI interact (Danio rerio)


name: Exocytosis of secretory granule lumen proteins (Saccharomyces cerevisiae)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Drosophila melanogaster)


name: Assembly of gap junction plaques (Homo sapiens)


name: epitestosterone + H(+) + NADPH = 5beta-dihydroepitestosterone + NADP(+)


name: H2O + N-methylmyosmine = pseudooxynicotine


name: Recruitment of Grb2 to pFAK:NCAM1 (Rattus norvegicus)


name: Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA (Homo sapiens)


name: Elastin cross-linking by lysyl oxidase (Bos taurus)


name: ATP + estrone 3-sulfate(out) + H2O = ADP + estrone 3-sulfate(in) + H(+) + phosphate


name: H2O + N-(9Z-octadecenoyl)-L-isoleucine => (9Z)-octadecenoate + L-isoleucine


name: GDP-alpha-D-rhamnose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: PPT2 hydrolyses PALMCoA to PALM (Homo sapiens)


name: H2O + NADP(+) + vanillin <=> 2 H(+) + NADPH + vanillate


name: SLC16A10-mediated uptake of aromatic amino acids (Plasmodium falciparum)


name: ADP + H(+) + Ni(2+)(in) + phosphate => ATP + H2O + Ni(2+)(out)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+) => a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O


name: (8Z,11Z,14Z)-eicosatrienoate + NH4(+) => (8Z,11Z,14Z)-eicosatrienamide + H2O


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Gallus gallus)


name: Phosphorylation of LIMK-1 by PAK (Homo sapiens)


name: 15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: Formation of hydroxylysyl-pyridinoline cross-links (Caenorhabditis elegans)


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Rattus norvegicus)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Homo sapiens)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose <=> beta-D-glucosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: (2E,6E)-farnesyl diphosphate => calarene + diphosphate


name: (S)-(-)-citronellal + H2O + NADP(+) => (S)-(-)-citronellate + 2 H(+) + NADPH


name: Acitretin binds to RAR:RXR (Drosophila melanogaster)


name: 24-methylenecycloartanol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = 6-(alpha-D-glucosaminyl)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Sus scrofa)


name: NQO1 interaction with ODC (Rattus norvegicus)


name: (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NAD(+) <=> 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADH


name: Passive I- efflux mediated by SLC5A8 (Bos taurus)


name: a ribonucleoside 3'-phosphate + H2O = a ribonucleoside + phosphate


name: BACH1 translocates from the cytosol to the nucleoplasm (Drosophila melanogaster)


name: PLK2 phosphorylates NPM1 (Gallus gallus)


name: EPHAs bind EFNAs (Caenorhabditis elegans)


name: diphosphate + longifolene => (2E,6E)-farnesyl diphosphate


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Bos taurus)


name: 8 AMP + 8 diphosphate + 8 H(+) + PF1022C + 4 S-adenosyl-L-homocysteine => 3 (R)-3-phenyllactate + (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine


name: Beta-catenin:TCF associates with BCL9 and PYGO (Danio rerio)


name: GGT dimers hydrolyse APAP-SG (Canis familiaris)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Gallus gallus)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(out) + ADP + H(+) + phosphate => (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(in) + ATP + H2O


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Rattus norvegicus)


name: carboxyspermidine + H(+) => CO2 + spermidine


name: 4-nitroaniline + 5D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one => 4-nitrophenyl-3-ketovalidamine


name: Pancreatic proteases degrade TCN1:RCbl (Sus scrofa)


name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol (Homo sapiens)


name: glycero-2-phosphocholine + H2O = glycerol + H(+) + phosphocholine


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Rattus norvegicus)


name: [(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose <=> [(1->4)-beta-D-glucosyl](n+1) + H(+) + UDP


name: Transport of SEC22B, TAP and PLC from ER to ERGIC (Mus musculus)


name: (E)-coniferol + A <=> (E)-coniferaldehyde + AH2


name: L-amino acid transmembrane transporter activity


name: Glutamine transport from astrocytes (Homo sapiens)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)


name: 3,4-dihydroxyphthalate + H(+) => 3,4-dihydroxybenzoate + CO2


name: RHOQ GAPs stimulate RHOQ GTPase activity (Drosophila melanogaster)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Plasmodium falciparum)


name: a neolactoside IV(3)-alpha-NeuGc-nLc4Cer + UDP-N-acetyl-alpha-D-galactosamine <=> a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer + H(+) + UDP


name: 3 Na(+)(out) + phosphate(out) <=> 3 Na(+)(in) + phosphate(in)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Mus musculus)


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Canis familiaris)


name: SCF-beta-TrCP ubiquitinylates IkB (Mus musculus)


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Schizosaccharomyces pombe)


name: a [peptide]-C-terminal (2S)-2-hydroxyglycine => a [peptide]-C-terminal amide + glyoxylate


name: protein C-terminal leucine carboxyl O-methyltransferase activity


name: PGRMC2 binds Hemes (Dictyostelium discoideum)


name: MTTP lipidates APOB-100, forming a pre-VLDL (Mus musculus)


name: Loading of PCNA - Sliding Clamp Formation (Drosophila melanogaster)


name: S1P binds S1PR3 in response to E2 stimulation (Rattus norvegicus)


name: chlorophyllide a + H(+) + NADPH + O2 = 7(1)-hydroxychlorophyllide a + H2O + NADP(+)


name: (S)-2,3-diaminopropanoate + ATP + citrate <=> 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + AMP + diphosphate


name: G-protein subunits dissociate from WNT:FZD complex (Sus scrofa)


name: Caspase mediated cleavage of APC (Mus musculus)


name: a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine => a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]


name: (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate => (7R,8S)-7,8-diammoniononanoate + ATP + CO2


name: SGMS2 transfers phosphocholine onto ceramide (Canis familiaris)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: PTK6 phosphorylates ARHGAP35 (Homo sapiens)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated FGFR4 phosphorylates PLCG1 (Xenopus tropicalis)


name: propane-1,3-diamine + sym-homospermidine => putrescine + spermidine


name: 4-nitrophenyl-3-ketovalidamine <=> 4-nitroaniline + 5D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one


name: (2E)-geranyl diphosphate => diphosphate + terpinolene


name: 3-amino-2-hydroxy-4-methoxybenzoate + ATP + nitrite => AMP + cremeomycin + diphosphate + H2O


name: 2-acetyl-3,4a,8,10,11,12a-hexahydroxy-1,4,4a,5,12,12a-hexahydrotetracene-1,12-dione + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + TAN-1612


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Bos taurus)


name: Mitochondrial BTD hydrolyses BCTN (Homo sapiens)


name: SUMOylation of MDC1 with SUMO1 (Xenopus tropicalis)


name: cyclohex-1-ene-1-carbonyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = cyclohexa-1,5-diene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]


name: a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-GMP => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O


name: Oxytocin receptor bind oxytocin (Xenopus tropicalis)


name: Expression of ARFGAP1 (GAP) (Homo sapiens)


name: ABCB1 transports xenobiotics out of the cell (Bos taurus)


name: (S)-dihydroorotate + menaquinone-8 = menaquinol-8 + orotate


name: (R)-adrenaline(in) + 2 H(+)(out) => (R)-adrenaline(out) + 2 H(+)(in)


name: (E)-6-(methylsulfanyl)hexanal oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-trihomomethionine


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADH + O2 => 4beta-hydroxymethyl-4alpha-methylzymosterol + H2O + NAD(+)


name: Class IV antihypertensives bind LTCC multimer (Caenorhabditis elegans)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 <=> 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O


name: H2O + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => (9Z)-octadecenoate + H(+) + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: PARVB interacts with Alpha-actinin (Mus musculus)


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Canis familiaris)


name: 3-methyl-2-oxobutanoate + L-alanine => L-valine + pyruvate


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Mus musculus)


name: L-phenylalanine(out) + S-methylmercury-L-cysteine(in) = L-phenylalanine(in) + S-methylmercury-L-cysteine(out)


name: an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + S-adenosyl-L-methionine = an N-methylornithine lipid + H(+) + S-adenosyl-L-homocysteine


name: O-acetyl-15alpha-stemmadenine + O2 <=> H2O2 + precondylocarpine acetate


name: citrate(out) + tartrate(in) => citrate(in) + tartrate(out)


name: Addition of galactose to Core 6 glycoprotein (Sus scrofa)


name: a ganglioside GM2 + H(+) + UDP => a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine


name: SLC7A10-mediated uptake of small neutral amino acids (Rattus norvegicus)


name: Translocation of ERBB4s80 to the nucleus (Rattus norvegicus)


name: 2-hydroxy-3-oxopropanoate + H(+) + NADPH => (R)-glycerate + NADP(+)


name: A + butanoyl-CoA = (2E)-butenoyl-CoA + AH2


name: FFAR1 binds rosiglitazone (Rattus norvegicus)


name: BTK in G alpha (12)-BTK complex is activated (Drosophila melanogaster)


name: 2 H(+) + O2 + rifamycin B => H2O2 + rifamycin O


name: RBKS phosphorylates ribose to R5P (Mus musculus)


name: acetyl-CoA + S-(2-succino)-L-cysteine = CoA + H(+) + N-acetyl-S-(2-succino)-L-cysteine


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Xenopus tropicalis)


name: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate


name: (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH => (1R,2S)-ephedrine + NAD(+)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Schizosaccharomyces pombe)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Danio rerio)


name: Spermidine  => N-acetylated spermidine (Schizosaccharomyces pombe)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Caenorhabditis elegans)


name: SREBP1A,1C,2 binds Importin beta-1 (Xenopus tropicalis)


name: dodecanoyl-CoA + NAD(+) => (2E)-dodecenoyl-CoA + H(+) + NADH


name: a 1,2-diacylglycerol + H2O <=> a fatty acid + a monoacylglycerol + H(+)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Homo sapiens)


name: ATP + holo-[peptidyl-carrier protein] + L-arginine => AMP + diphosphate + L-arginyl-[peptidyl-carrier protein]


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Schizosaccharomyces pombe)


name: an anthocyanidin + H(+) + UDP-alpha-D-glucose <=> an anthocyanidin 3-O-beta-D-glucoside + UDP


name: an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O => an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity


name: PIAS1,4 SUMOylates BRCA1 with SUMO2,3 (Sus scrofa)


name: H(+) + isopentenyl phosphate + phosphate => H2O + isopentenyl diphosphate


name: 3',5'-cyclic GMP + NAD(+) <=> H(+) + N(2)-(ADP-D-ribosyl)-3',5'-cyclic GMP + nicotinamide


name: H2O + queuosine 5'-phosphate = D-ribose 5-phosphate + queuine


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Caenorhabditis elegans)


name: Initial activation of proMMP2 by MMP1, 7 (Danio rerio)


name: 3-hydroxytetradecanoate + ATP + CoA => 3-hydroxytetradecanoyl-CoA + AMP + diphosphate


name: 4-methylamino-L-phenylalanine + S-adenosyl-L-methionine = 4-dimethylamino-L-phenylalanine + H(+) + S-adenosyl-L-homocysteine


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Bos taurus)


name: Expression of ZIC2 in anterior neural plate (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N-(20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: ATP + H2O + Mn(2+)(in) => ADP + H(+) + Mn(2+)(out) + phosphate


name: Activated PCLG1 dissociates from NTRK2 (Rattus norvegicus)


name: STAT binds to p-11Y PDGFRA extracellular domain dimers  (Homo sapiens)


name: TPX2 binds AURKA at centrosomes (Homo sapiens)


name: dodecanoyl-CoA + hexadecan-1-ol = CoA + hexadecanyl dodecanoate


name: H(+) + N,N-dihydroxy-L-isoleucine = (1E,2S)-2-methylbutanal oxime + CO2 + H2O


name: OCT1 transports organic cations into hepatic cells (Sus scrofa)


name: p-Y420-FYN is phosphorylated on S21 (Homo sapiens)


name: (22S)-22-hydroxycampest-4-en-3-one + O2 + reduced [NADPH--hemoprotein reductase] = (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4 H(+) + N(6)-dimethyladenosine(1914)/N(6)-dimethyladenosine(1915) in 18S rRNA + 4 S-adenosyl-L-homocysteine => adenosine(1914)/adenosine(1915) in 18S rRNA + 4 S-adenosyl-L-methionine


name: 3-oxoisoapionate 4-phosphate + H(+) = CO2 + L-erythrulose 1-phosphate


name: (3R)-hydroxydodecanoyl-[ACP] <=> (2E)-dodecenoyl-[ACP] + H2O


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Rattus norvegicus)


name: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity


name: IKK complex is activated by PKR (Sus scrofa)


name: Autophosphorylation of PAK1 (Mus musculus)


name: 7beta-hydroxytaxusin + O2 + reduced [NADPH--hemoprotein reductase] = 2alpha,7beta-dihydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H(+) + S-adenosyl-L-homocysteine => (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine


name: STAT3 binds TSLP:IL7R:CRLF2 (Homo sapiens)


name: abieta-7,13-dien-18,18-diol <=> abieta-7,13-dien-18-al + H2O


name: IL37 binds 2x(CASP1(120-197):CASP1(317-404)) (Canis familiaris)


name: dodecan-1-ol + NADP(+) => dodecanal + H(+) + NADPH


name: CCNK binds CDK12 (Caenorhabditis elegans)


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Danio rerio)


name: (5S,9S,10S)-drim-7-en-11-ol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: 15-oxoprostaglandin E2 + H(+) + NADPH => NADP(+) + prostaglandin E2


name: 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + CO2 + CoA => (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + malonyl-CoA


name: Cleavage of DFF45 (224) by caspase-3 (Homo sapiens)


name: 3-demethylubiquinol-10 + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + ubiquinol-10


name: SRC-1 phosphorylates p-Y397-PTK2 (Homo sapiens)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Danio rerio)


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Gallus gallus)


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Gallus gallus)


name: ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi (Bos taurus)


name: ProGIP translocates from the ER Lumen to secretory granules (Homo sapiens)


name: formate + GTP + H(+) => CO2 + dGTP + H2O


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Drosophila melanogaster)


name: Translocation of activated BAD protein to mitochondria (Rattus norvegicus)


name: chloride(out) + 2 hydrogencarbonate(in) = chloride(in) + 2 hydrogencarbonate(out)


name: cyclo(L-leucyl-L-leucyl) + 4 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] + pulcherriminic acid


name: Thyrotropin-releasing hormone receptor binds thyrotropin (Bos taurus)


name: RAF phosphorylates MAP2K dimer (Mus musculus)


name: PEX3:PEX19:class I PMP dissociates (Bos taurus)


name: H(+)(in) + thiamine(out) <=> H(+)(out) + thiamine(in)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O <=> (S)-2-amino-6-oxoheptanedioate


name: delta-cadinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H2O => 6-deoxy-6-sulfo-D-gluconate + H(+)


name: 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity


name: TFPA2A homodimer and NPM1 bind the NOP2 gene promoter (Homo sapiens)


name: 7alpha-hydroxycholest-4-en-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ARSA removes sulfate from PSAP(195-273):Sulfatide (Mus musculus)


name: Collagen type XII degradation by MMP12 (Mus musculus)


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Gallus gallus)


name: 1,1,1-trichloroethane reductive dehalogenase activity


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Xenopus tropicalis)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Dictyostelium discoideum)


name: D-ribose + H2O + NADP(+) => D-ribonate + 2 H(+) + NADPH


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Caenorhabditis elegans)


name: RHOC activates endoplasmic reticulum effectors (Schizosaccharomyces pombe)


name: coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] => coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n)


name: (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + S-adenosyl-L-methionine <=> (2R)-4-(dimethylsulfaniumyl)-2-hydroxybutanoate + S-adenosyl-L-homocysteine


name: 1D-myo-inositol 2,3,4,5-tetrakisphosphate + H2O <=> 1D-myo-inositol 2,4,5-triphosphate + phosphate


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Rattus norvegicus)


name: H2O + streptothricin D <=> streptothricin D acid


name: Autoproteolytic cleavage of Hh precursors (Gallus gallus)


name: RHOU binds effectors at the plasma membrane (Drosophila melanogaster)


name: a globoside DSGG + CMP + H(+) => a globoside MSGG + CMP-N-acetyl-beta-neuraminate


name: B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Danio rerio)


name: 2-(3,5-dihydroxyphenyl)-2-oxoacetate + CoA + H(+) => (3,5-dihydroxyphenyl)acetyl-CoA + O2


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine = (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: beta-D-Gal-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP => N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Drosophila melanogaster)


name: Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)


name: L-asparagine transmembrane transporter activity


name: PSMD14 cleaves K63-linked ubiquitin (Plasmodium falciparum)


name: Phosphorylated SHC recruits GRB2:SOS1 (Rattus norvegicus)


name: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(+) + NADPH + O2 => 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + H2O + NADP(+)


name: D-sedoheptulose 1,7-bisphosphate + H2O <=> D-sedoheptulose 7-phosphate + phosphate


name: RNASEL cleaves cellular ssRNA (Homo sapiens)


name: 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NAD(+) => anthraniloyl-CoA + 2 H(+) + 2 NADH + O2


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene = 1,2,4-trichlorobenzene + chloride + H(+)


name: ribonucleotidyl-uridine-RNA => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-uridine-RNA


name: H(+) + indolmycin + S-adenosyl-L-homocysteine => N-demethylindolmycin + S-adenosyl-L-methionine


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O = beta-eudesmol + diphosphate


name: 2-oxoglutarate + deacetoxycephalosporin C + O2 = CO2 + deacetylcephalosporin C + succinate


name: luteolin + UDP-alpha-D-glucose => H(+) + isoorientin + UDP


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Xenopus tropicalis)


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Saccharomyces cerevisiae)


name: a 4,5-saturated-(2E)-enoyl-CoA + NADP(+) => a (2E,4E)-dienoyl-CoA + H(+) + NADPH


name: E2F6 binds APAF1 gene promoter (Homo sapiens)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Rattus norvegicus)


name: NRXNs bind CASK:Protein 4.1 (Danio rerio)


name: p-SHC1 binds integrin alpha5beta1:fibronectin (Sus scrofa)


name: bisphenol A + H(+) + NADH + O2 => 2,2-bis(4-hydroxyphenyl)-1-propanol + H2O + NAD(+)


name: TSEN complex cleaves the intron from pre-tRNA (Homo sapiens)


name: (6R)-10-formyltetrahydrofolate + H2O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH


name: 2-oxoglutarate(in) + citrate(out) => 2-oxoglutarate(out) + citrate(in)


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Mus musculus)


name: SLMB binds to and ubiquitinates phosphorylated CI (Drosophila melanogaster)


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Rattus norvegicus)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Saccharomyces cerevisiae)


name: PKR inhibitors bind PKR (Canis familiaris)


name: Proton-coupled di- and tri-peptide cotransport (Rattus norvegicus)


name: 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate <=> H2O + ML-236C carboxylate


name: ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H2O + L-glutamine = ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + L-glutamate + phosphate


name: "lipid II isoglutaminyl synthase (glutamine-hydrolyzing)"


name: ESR1 binds to TFF1 gene promoter (Homo sapiens)


name: Regulation of KIF23 (MKLP1) by phosphorylation (Xenopus tropicalis)


name: ADP(out) + CoA(in) => ADP(in) + CoA(out)


name: Activated CIT binds KIF14 and PRC1 (Drosophila melanogaster)


name: 2-oxoglutarate(out) + glutarate(in) => 2-oxoglutarate(in) + glutarate(out)


name: Recruitment of IRF to activated TBK1/IKK epsilon (Gallus gallus)


name: ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate => ATP + L-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine


name: (2S,6S)-2,6-diaminoheptanedioate + acetate => H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate


name: androst-5-en-3beta,17beta-diol + O2 + reduced [NADPH--hemoprotein reductase] => androst-5-en-3beta,7alpha,17beta-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PPM1D dephosphorylates RUNX2 (Caenorhabditis elegans)


name: IL12 bound to IL12R internalises (Sus scrofa)


name: H2O2 + L-xylo-hex-3-ulonolactone => L-gulono-1,4-lactone + O2


name: 3-oxohexadecanedioyl-CoA + H(+) + NADH => (3R)-hydroxyhexadecanedioyl-CoA + NAD(+)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Mus musculus)


name: The distal appendage proteins recruit TTBK2 (Sus scrofa)


name: NADH + 2 O2 => H(+) + NAD(+) + 2 superoxide


name: L-methionyl-[protein] + S-adenosyl-L-methionine <=> S-adenosyl-L-homocysteine + S-methyl-L-methionyl-[protein]


name: TYK2-dependent STAT1 and STAT3 phosphorylation (Homo sapiens)


name: SHANK proteins bind GKAPs (Homo sapiens)


name: LTD4 is converted to LTE4 by DPEP1/2 (Mus musculus)


name: Movement of clathrin coated vesicles into early endosome (Caenorhabditis elegans)


name: 1,4-diguanidinobutane + H2O <=> agmatine + urea


name: Sprouty sequesters CBL away from active EGFR (Mus musculus)


name: L-gulonate + NAD(+) => H(+) + keto-D-fructuronate + NADH


name: acetaldehyde + fumagillin + H2O + NADP(+) => NADPH + 2 O2 + prefumagillin


name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Dictyostelium discoideum)


name: (S)-cystathionine ketimine + 2 H(+) + NADPH <=> (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NADP(+)


name: Furin cleaves pro-protein Z to protein Z (Danio rerio)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Rattus norvegicus)


name: Initial proteolyis of Ii by aspartic proteases to lip22 (Bos taurus)


name: H2O + N-acetyl-4-O-acetylneuraminate <=> acetate + H(+) + N-acetylneuraminate


name: SUMOylation of TOP2A with SUMO1 (Dictyostelium discoideum)


name: A4GNT transfers GlcNAc to core 2 mucins (Canis familiaris)


name: chloride(out) + L-methionine(out) + 2 Na(+)(out) => chloride(in) + L-methionine(in) + 2 Na(+)(in)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Danio rerio)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Drosophila melanogaster)


name: CARMA1:BCL10:MALT1 complex recruits TAK1 and IKK (Homo sapiens)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Xenopus tropicalis)


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Schizosaccharomyces pombe)


name: Translocation of STAT1 dimer to nucleus (Canis familiaris)


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Canis familiaris)


name: GMPS dimer transforms 6TXMP to 6TGMP (Gallus gallus)


name: NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Gallus gallus)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Danio rerio)


name: O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + H(+) + UDP


name: dimethylallyl diphosphate + L-tryptophan => 4-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: Association of Rb with Cyclin E:Cdk2 complexes (Bos taurus)


name: SMURF1/2 dissociates from ub-PTCH1 (Sus scrofa)


name: 3'-phosphoadenylyl sulfate + testosterone 17-O-(beta-D-glucuronate) <=> adenosine 3',5'-bisphosphate + H(+) + testosterone 17-O-(3-sulfo-beta-D-glucuronate)


name: methanethiol + S-adenosyl-L-methionine <=> dimethyl sulfide + H(+) + S-adenosyl-L-homocysteine


name: p-S207 KARS1 dimer translocates to the nucleus (Sus scrofa)


name: DOLK phosphorylates DCHOL to DOLP (Homo sapiens)


name: L-aspartate 4-semialdehyde + pyruvate <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O


name: NAD(+) + propanoyl-CoA = acryloyl-CoA + H(+) + NADH


name: IRF3 is phosphorylated by TBK1 (Sus scrofa)


name: 4-amino-4-deoxychorismate + H2O => chorismate + NH4(+)


name: NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity


name: a 3-(omega-methylsulfanyl)alkylmalate => a 2-(omega-methylsulfanyl)alkylmalate


name: hexadecanoyl-CoA + N-terminal glycyl-[protein] <=> CoA + H(+) + N-terminal N(6)-hexadecanoylglycyl-[protein]


name: Recruitment of Telomerase RNP to the Telomeric Chromosome End (Rattus norvegicus)


name: L-alanine(in) + L-phenylalanine(out) <=> L-alanine(out) + L-phenylalanine(in)


name: acetyl-CoA + N-terminal L-(Asp/Glu)3-[protein] <=> CoA + H(+) + N-terminal N-acetyl-L-(Asp/Glu)3-[protein]


name: 2,5-diformylfuran + H2O <=> 2-(dihydroxymethyl)-5-formylfuran


name: glycine + H2O + O2 => glyoxylate + H2O2 + NH4(+)


name: KSPG is secreted from the cell (Sus scrofa)


name: Activated ERBB2 binds PTK6 (BRK) (Bos taurus)


name: LONP1 binds mitochondrial inner membrane proteins (Sus scrofa)


name: box C/D methylation guide snoRNP complex binding


name: LARG activation by G alpha 12/13 (Canis familiaris)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + ATP => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+)


name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Bos taurus)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Rattus norvegicus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA


name: ERBB4 ubiquitination by WWP1/ITCH (Caenorhabditis elegans)


name: (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 => (7S,17S)-dihydroperoxy-(4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoate


name: NADP(+) + neomorphine <=> H(+) + NADPH + neomorphinone


name: 2 3-(4-hydroxyphenyl)pyruvate = aspulvinone E + H2O


name: 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Sus scrofa)


name: Ub-RibC-AXIN is degraded by the proteasome (Homo sapiens)


name: (1R,2R,3R)-prephytoene diphosphate + diphosphate => 2 (2E,6E,10E)-geranylgeranyl diphosphate


name: atROL binds RBP1 to form RBP1:atROL (Xenopus tropicalis)


name: TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Homo sapiens)


name: H(+) + propanoyl-CoA + sulfite => 3-sulfinopropanoyl-CoA + H2O


name: 3-dehydrocarnitine + acetyl-CoA = acetoacetate + N,N,N-trimethylglycyl-CoA


name: H2O + phosphocholine <=> choline + phosphate


name: Expression of PAX7 in the neural plate border (Homo sapiens)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Gallus gallus)


name: H2O + NAD(+) + succinate semialdehyde + trimethylamine => 4-(trimethylamino)butanoate + H(+) + NADH + O2


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Xenopus tropicalis)


name: NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity


name: Activated FGFR2 binds SHC1 (Gallus gallus)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Sus scrofa)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + ethanolamine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + choline


name: H2O + NADP(+) + pentalenolactone D => 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2


name: coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2


name: "coproporphyrinogen III oxidase (coproporphyrin-forming)"


name: diphosphate + L-serine = H(+) + O-phospho-L-serine + phosphate


name: C-ter TLR9 dimer binds HCQ (Rattus norvegicus)


name: a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] => an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: PE is hydrolyzed to 2-acyl LPE by PLA2G4C (Homo sapiens)


name: 1-hexadecanoylglycerone 3-phosphate + pentadecan-1-ol = 1-O-pentadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + CoA


name: PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV (Homo sapiens)


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Rattus norvegicus)


name: Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Mus musculus)


name: CHOL translocates from lysosome membrane to ER membrane (Drosophila melanogaster)


name: ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 (Homo sapiens)


name: Fe-coproporphyrin III + H(+) + H2O2 = CO2 + 2 H2O + harderoheme III


name: H(+) + NADPH + neopatulin = (E)-ascladiol + NADP(+)


name: STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Canis familiaris)


name: MME:Zn2+ binds sacubitrilat (Homo sapiens)


name: propionate transmembrane transporter activity


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)


name: ZnT8 transports zinc into the Golgi apparatus (Xenopus tropicalis)


name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Mus musculus)


name: ERKs are inactivated by protein phosphatase 2A (Bos taurus)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> mutildienyl diphosphate


name: (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + octanoyl-CoA => (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + CoA


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Rattus norvegicus)


name: (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H2O => (Z)-1-(glycyl-L-cystein-S-yl)-2-phenylacetohydroximate + L-glutamate


name: a 1,2-diacyl-sn-glycerol(in) = a 1,2-diacyl-sn-glycerol(out)


name: H(+) + NADPH + O2 + urate = 5-hydroxyisourate + H2O + NADP(+)


name: ATF6B:HSPA5 (ATF6-beta:BiP) dissociates and HSPA5 binds unfolded protein (Homo sapiens)


name: Activated glucocorticoid receptor binds NPAS4 gene promoter (Homo sapiens)


name: androst-5-en-3beta,17beta-diol + O2 + reduced [NADPH--hemoprotein reductase] = androst-5-en-3beta,7alpha,17beta-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RHOD binds effectors at the mitochondrial outer membrane (Rattus norvegicus)


name: abieta-7,13-diene + diphosphate => (+)-copalyl diphosphate


name: Vamp7 associated Lysosome to Plasma membrane transport (Xenopus tropicalis)


name: CYP17A1 17-hydroxylates P4 to 17aHPROG (Sus scrofa)


name: POLI incorporates dNMP opposite to damaged DNA base (Saccharomyces cerevisiae)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Sus scrofa)


name: (2-aminobenzoyl)acetate + CoA + H(+) => (2-aminobenzoyl)acetyl-CoA + H2O


name: AMP + diphosphate + L-tyrosinal + NADP(+) => ATP + H(+) + L-tyrosine + NADPH


name: (E)-sinapyl alcohol + NADP(+) => (E)-sinapaldehyde + H(+) + NADPH


name: Clusterin binds C5b-C7, C8, C9 (Homo sapiens)


name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Canis familiaris)


name: diphosphate + Fe(II)-heme o => (2E,6E)-farnesyl diphosphate + H2O + heme b


name: ATP + H2O + Mg(2+)(out) <=> ADP + H(+) + Mg(2+)(in) + phosphate


name: eicosanoyl-CoA + sphing-4-enine <=> CoA + H(+) + N-eicosanoyl-sphing-4-enine


name: PEX19:class I PMP binds PEX3 (Canis familiaris)


name: glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] (Homo sapiens)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Homo sapiens)


name: K63polyUb-TRAF6 ubiquitinates TAK1 (Sus scrofa)


name: Release of GABA at the synapse (Homo sapiens)


name: 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Danio rerio)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Canis familiaris)


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Bos taurus)


name: [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + ADP => [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ATP


name: NAD(+) + S-(hydroxymethyl)mycothiol => H(+) + NADH + S-formylmycothiol


name: H2O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Homo sapiens)


name: p-S276-RELA binds RELB (Drosophila melanogaster)


name: 2 H(+) + NADH + tetradecanoate => H2O + NAD(+) + tetradecanal


name: a ganglioside Fuc-GD1b + GDP + H(+) => a ganglioside GD1b + GDP-beta-L-fucose


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Sus scrofa)


name: cholate + deoxycholoyl-CoA = choloyl-CoA + deoxycholate


name: GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate <=> GDP + H(+) + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: Phosphorylated AP-1, Phospho JRA:Phospho KAY binds to a target gene and activates transcription (Drosophila melanogaster)


name: p-T38-PPP1R14A binds MLCP (Canis familiaris)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine


name: Sequestration of BAD protein by 14-3-3 (Canis familiaris)


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Bos taurus)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Drosophila melanogaster)


name: [thioredoxin]-disulfide + prostamide F2alpha <=> [thioredoxin]-dithiol + prostamide H2


name: Association of LBP with LPS (Homo sapiens)


name: ganglioside GT1b (d18:1(4E)/18:0) + H2O = ganglioside GD1b(d18:1(4E)/18:0) + N-acetylneuraminate


name: L-lysine + 2 S-adenosyl-L-methionine => 2 H(+) + N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine


name: (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O2 => (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + O2


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Mus musculus)


name: G-protein beta-gamma subunits rebind the alpha-GDP subunit (Homo sapiens)


name: NTF3-bound NTRK2 dimerizes (Homo sapiens)


name: K+-independent Li+/Ca2+ exchanger transport (Schizosaccharomyces pombe)


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA <=> (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA + H2O


name: SYK binds to p-Y65,Y76-FCER1G (Mus musculus)


name: 5-methylcytidine(2499) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(2499) in 23S rRNA + S-adenosyl-L-methionine


name: RGS proteins bind GNB5 and CCT/TRiC (Gallus gallus)


name: Phosphorylated YBX1 translocates to the nucleus (Rattus norvegicus)


name: DHF is reduced to tetrahydrofolate (THF) (Sus scrofa)


name: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate


name: TYRP1 oxidises DHICA to IQCA (Mus musculus)


name: N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: NTPDase2 hydrolyzes nucleoside triphosphates (Mus musculus)


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Bos taurus)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Rattus norvegicus)


name: intercellular adhesion molecule-3 receptor binding


name: AXIN mutants destabilize the destruction complex (Homo sapiens)


name: DHAP is converted to G3P by GPD1/GPD1L (Plasmodium falciparum)


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Homo sapiens)


name: a ubiquinone + D-alanine + H2O => a ubiquinol + NH4(+) + pyruvate


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 4beta-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Hemoglobin:Haptoglobin:CD163 is endocytosed (Rattus norvegicus)


name: Mitochondrial recruitment of Drp1 (Rattus norvegicus)


name: 2 H2O + ricinine => 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate + NH4(+)


name: PILRA binds PIANP, COLLEC12 trimer, NPDC1, CLEC4G (Bos taurus)


name: Interaction of integrin alphaVbeta3 with Tenascin (Caenorhabditis elegans)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Mus musculus)


name: DBT transfers BCAA to CoA (Canis familiaris)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Rattus norvegicus)


name: 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol


name: G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Sus scrofa)


name: 2 H2O + NADP(+) + versicolorin A => H(+) + NADPH + O2 + versicolorin B


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Mus musculus)


name: D-galactose 6-phosphate + NAD(+) => 6-phospho-D-galactono-1,5-lactone + H(+) + NADH


name: L-glutamate + N-acetyl-L-aspartate => H2O + N-acetyl-L-aspartyl-L-glutamate


name: Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Gallus gallus)


name: 4-methyl-3-oxohexanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxy-4-methylhexanoyl-[ACP] + NADP(+)


name: CEBPB homodimerization (Drosophila melanogaster)


name: a long-chain (2E)-enoyl-CoA + H2O => a long-chain (3R)-hydroxyacyl-CoA


name: NTPDase3 hydrolyzes nucleoside diphosphates (Bos taurus)


name: Elastin degradation by elastin-degrading extracellular proteinases (Sus scrofa)


name: N,N-dihydroxy-L-aspartate = (2S)-2-nitrosobutanedioate + H2O


name: alpha-himachalene + diphosphate => (2E,6E)-farnesyl diphosphate


name: benzoate + 2 H(+) + NADPH => benzaldehyde + H2O + NADP(+)


name: CES1trimer hydrolyses ACEI pro-drugs to ACEIs (Danio rerio)


name: MIB2 ubiquitinates CYLD at K338, K530 (Sus scrofa)


name: D-xylotriono-1,5-lactone + H2O2 => D-xylotriose + O2


name: RAC1:GTP binds NOX3 complex (Canis familiaris)


name: Protein 4.1 binds CASK (Caenorhabditis elegans)


name: Cdc45 associates with the pre-replicative complex at the origin (Sus scrofa)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine => 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O


name: 2-deoxyecdysone 22-phosphate + H2O => 2-deoxyecdysone + phosphate


name: pre-VLDL translocates from RER membrane to SER lumen (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (3E,7E)-dolathalia-3,7,11-triene + diphosphate


name: H2O + tridodecanoylglycerol => 2,3-didodecanoyl-sn-glycerol + dodecanoate + H(+)


name: H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] <=> N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate


name: [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + H2O + NADP(+) => [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + H(+) + NADPH + O2


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Dictyostelium discoideum)


name: corticosterone + NAD(+) => 11-dehydrocorticosterone + H(+) + NADH


name: H(+) + O-phospho-L-serine => CO2 + phosphoethanolamine


name: PHF8 demethylates histone H4K20me1 (Caenorhabditis elegans)


name: Na+-driven Cl-/HCO3- exchanger transport (Bos taurus)


name: AH2 + N-acetyl-S-hydroxy-L-cysteine => A + H2O + N-acetyl-L-cysteine


name: 2,5-dihydroxybenzoate + O2 = 3-maleylpyruvate + H(+)


name: an N-(fatty acyl)-L-serine + H2O <=> a fatty acid + L-serine


name: Interaction of integrin alphaVbeta3 with Tenascin (Gallus gallus)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Xenopus tropicalis)


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA <=> (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA + H2O


name: AMP + H2O => adenosine + orthophosphate [NT5C1B] (Rattus norvegicus)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Mus musculus)


name: NEIL3 cleaves 5-guanidinohydantoin (Bos taurus)


name: Autocleavage of ESPL1 (Separase) (Schizosaccharomyces pombe)


name: DVL2 binds phosphorylated WWTR1 (TAZ) (Mus musculus)


name: UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity


name: FMN + H(+) + oxidized coenzyme F420-0 <=> dehydro coenzyme F420-0 + FMNH2


name: 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate


name: adenosine + H(+) + tuberculosinyl diphosphate <=> 1-tuberculosinyladenosine + diphosphate


name: Loading of antigen peptide onto MHC class I molecule (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphocholine + a 1-acylglycerol => a 1,2-diacyl-sn-glycero-3-phosphocholine + glycerol


name: ATXN3 deubiquitinates polyUb-PARK2 (Mus musculus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + tetradecanoyl-CoA => 1-O-hexadecyl-2-acetyl-3-tetradecanoyl-sn-glycerol + CoA


name: (11Z)-octadecenoyl-CoA + NADP(+) => (2E,11Z)-octadecadienoyl-CoA + H(+) + NADPH


name: an S-substituted L-cysteine + glycine => an S-substituted L-cysteinylglycine + H2O


name: NFE2L2 dependent ATF4 expression (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: MHC class II antigen processing (Sus scrofa)


name: beta-D-fructose 1-phosphate => D-glyceraldehyde + dihydroxyacetone phosphate


name: 5-methyluridine(747) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(747) in 23S rRNA


name: quillate + UDP-alpha-D-glucose => quillaic acid 28-beta-D-glucoside + UDP


name: 2 H2O + ITP => 2 H(+) + IMP + 2 phosphate


name: H2O + malonaldehyde + NAD(+) <=> 3-oxopropanoate + 2 H(+) + NADH


name: all-trans-heptaprenyl diphosphate + sn-glycerol 1-phosphate = 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate


name: RHOA:GTP translocates to the ER membrane (Drosophila melanogaster)


name: L-aspartate(in) + L-tryptophan(out) = L-aspartate(out) + L-tryptophan(in)


name: 2-oxoglutarate + H(+) + O2 + trihazone A => 2 CO2 + H2O + succinate + trihazone D


name: PDPK1 binds PIP3 (Saccharomyces cerevisiae)


name: an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine = an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine


name: trans-zeatin-O-glucoside UDP glycosyltransferase activity


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-diphosphate + H2O <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + phosphate


name: Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Rattus norvegicus)


name: SRD5A2 dehydrogenates TEST to DHTEST (Sus scrofa)


name: neutral, basic amino acid:sodium:chloride symporter activity


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Sus scrofa)


name: CoA + H(+) + N-tetracosenoyl-heptadecasphing-4-enine => heptadecasphing-4-enine + tetracosenoyl-CoA


name: BRAF autophosphorylates downstream of RAP1 and NGF (Mus musculus)


name: β-blockers bind ADRB1,2,3 (Rattus norvegicus)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)


name: a ganglioside GA2 + UDP-alpha-D-galactose <=> a ganglioside GA1 + H(+) + UDP


name: TP53 forms homotetramers (Rattus norvegicus)


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) = 5alpha-androstan-3,17-dione + H(+) + NADPH


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Rattus norvegicus)


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Mus musculus)


name: CHSY1 transfers GlcA to chondroitin (Mus musculus)


name: TOPORS SUMOylates SIN3A with SUMO1 (Gallus gallus)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Caenorhabditis elegans)


name: H2O + N-(6-aminohexanoyl)-6-aminohexanoate => 2 6-aminohexanoate


name: 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH => 7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+)


name: UMPS dimer decarboxylates OMP to UMP (Sus scrofa)


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Canis familiaris)


name: Pol II elongation complex moves on the template as transcript elongates (Mus musculus)


name: NME1,2 hexamers phosphorylate RBV-DP (Bos taurus)


name: p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Bos taurus)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Mus musculus)


name: ADP-D-ribose + H2O => AMP + D-ribose 5-phosphate + 2 H(+)


name: TRAF6 binds to p75NTR:NRIF (Rattus norvegicus)


name: (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA + NAD(+) = 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + H(+) + NADH


name: RAC2 GEFs activate RAC2 (Canis familiaris)


name: RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity


name: a neolactoside IV(3)-alpha-GalNAc,IV(2)-alpha-Fuc-nLc4Cer(d18:0) + H2O = a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:0) + N-acetyl-alpha-D-galactosamine


name: 22-oxodocosanoate + H(+) + NADH => 22-hydroxydocosanoate + NAD(+)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Xenopus tropicalis)


name: D-erythrose 4-phosphate => D-erythrulose 4-phosphate


name: 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O <=> 2 AMP + H(+)


name: Autophosphorylation of insulin receptor (Danio rerio)


name: PRKACA phosphorylates PLN (Rattus norvegicus)


name: Interaction of integrin alphaVbeta3 with Tenascin (Sus scrofa)


name: [protein]-peptidylproline (omega=0) => [protein]-peptidylproline (omega=180)


name: holo-FDPS dimer binds NBPs (Homo sapiens)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> (R)-axinyssene + diphosphate


name: 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: kaempferol + S-adenosyl-L-methionine => H(+) + kaempferol 7-methyl ether + S-adenosyl-L-homocysteine


name: D-galactose(in) + 2 Na(+)(in) => D-galactose(out) + 2 Na(+)(out)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Sus scrofa)


name: 3-methylcyclohexanone + H(+) + NADH + NH4(+) => (1S)-3-methyl-cyclohexylamine + H2O + NAD(+)


name: MAF1 translocates to the nucleus (Sus scrofa)


name: Formation of classic pathway C5 convertase (Mus musculus)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Dictyostelium discoideum)


name: A + L-pipecolate => AH2 + H(+) + L-1-piperideine-6-carboxylate


name: alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity


name: ATP + H(+) + NADPH + picolinate = AMP + diphosphate + NADP(+) + picolinal


name: 3-methylbutanoyl-CoA + H2O => 3-methylbutanoate + CoA + H(+)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Mus musculus)


name: Telomere shortening during replicative exhaustion (Mus musculus)


name: [phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + H(+) + methanol


name: Active FLT3 phosphorylates CDKN1B (Bos taurus)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  upon TLR7/8 or 9 activation (Rattus norvegicus)


name: acetoacetate + H(+) + methylglyoxal = 3-hydroxyhexane-2,5-dione + CO2


name: SOCS3 binds activated PTK6 (Homo sapiens)


name: phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: GUK1 phosphorylates 6TGMP to 6TGDP (Saccharomyces cerevisiae)


name: Dicer cleaves pre-miRNA to yield duplex miRNA (Homo sapiens)


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Homo sapiens)


name: 10-hydroxydecanoate + NAD(+) => 10-oxodecanoate + H(+) + NADH


name: Translocation of activated BAD protein to mitochondria (Xenopus tropicalis)


name: Activation of BAD by calcineurin (Mus musculus)


name: 15-oxoprostaglandin E2 + H(+) + NADPH => 13,14-dihydro-15-oxo-prostaglandin E2 + NADP(+)


name: p-Y693-STAT4, p-Y705-STAT3 dissociate from IL23:IL23 receptor (Homo sapiens)


name: (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA + H(+) + NADPH => (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+)


name: PNPLA6 hydrolyzes LysoPtdCho (Canis familiaris)


name: 4-methyl-2-oxopentanoate(out) + H(+)(out) => 4-methyl-2-oxopentanoate(in) + H(+)(in)


name: ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) <=> ADP-D-glycero-beta-D-manno-heptose + diphosphate


name: MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Bos taurus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Saccharomyces cerevisiae)


name: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) <=> (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Gallus gallus)


name: DOLK phosphorylates DCHOL to DOLP (Bos taurus)


name: Trafficking of nonameric complex in the endocytic pathway (Canis familiaris)


name: Epithelial cadherin binds to KLRG1 (Homo sapiens)


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Rattus norvegicus)


name: Inactive G alpha (z) reassociates with G beta:gamma (Sus scrofa)


name: acetyl-CoA + N-terminal L-leucyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-leucyl-[protein]


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Bos taurus)


name: FAD-dependent urate hydroxylase activity


name: (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-2,6-dimethyloct-6-enoyl-CoA + NAD(+) <=> (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + H(+) + NADH


name: ABC-type phosphonate transporter activity


name: [DsbA protein]-dithiol + a quinone => [DsbA protein]-disulfide + a quinol


name: GSDME expression mediated by TP53, TP63 (Homo sapiens)


name: Na(+)(in) + O-propanoyl-(R)-carnitine(in) => Na(+)(out) + O-propanoyl-(R)-carnitine(out)


name: H2O + Xaa-L-Pro dipeptide => an L-alpha-amino acid + L-proline


name: AXIN is phosphorylated in the destruction complex (Sus scrofa)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Gallus gallus)


name: GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)


name: RANBP2 SUMOylates SP100 with SUMO2 (Rattus norvegicus)


name: a ganglioside GD1a (d18:1(4E)) + CMP + H(+) => a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + ATP + CoA = (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoyl-CoA + AMP + diphosphate


name: CDC42 GEFs activate CDC42 (Schizosaccharomyces pombe)


name: NOTCH1 HD domain mutants bind DLL4 (Homo sapiens)


name: 7,8-dihydroneopterin 3'-phosphate + H2O => 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate


name: 2 L-cysteine + NAD(+) = H(+) + L-cystine + NADH


name: CO2 + H2O + NAD(+) + naphthalene-1,2-diol => 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2


name: L-cysteinyl-[protein] + octadecanoyl-CoA = CoA + S-octadecanoyl-L-cysteinyl-[protein]


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Dictyostelium discoideum)


name: a cytidine in RNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in RNA + H(+) + S-adenosyl-L-homocysteine


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-prolyl-[protein] => acetyl-CoA + N-terminal L-prolyl-[protein]


name: NADP(+) + xylitol => D-xylose + H(+) + NADPH


name: Hemes bind to CLEC1B dimer (Mus musculus)


name: adenosylcob(III)inamide phosphate + GTP + H(+) <=> adenosylcob(III)inamide-GDP + diphosphate


name: [thioredoxin]-disulfide + dGDP + H2O = [thioredoxin]-dithiol + GDP


name: H(+) + roseoflavin + S-adenosyl-L-homocysteine => 8-demethyl-8-(methylamino)riboflavin + S-adenosyl-L-methionine


name: (11Z)-eicosenoyl-CoA + AH2 + O2 <=> (8Z,11Z)-eicosadienoyl-CoA + A + 2 H2O


name: glycine + phenylacetyl-CoA = CoA + H(+) + phenylacetylglycine


name: RHAG transports CO2 from extracellular region to cytosol (Caenorhabditis elegans)


name: Extracellular BTD hydrolyses BCTN (Homo sapiens)


name: ATP + taurocyamine => ADP + H(+) + N-phosphotaurocyamine


name: pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity


name: CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 (Bos taurus)


name: Formation of translation initiation complexes containing mRNA that does not circularize (Bos taurus)


name: D-arabinitol + NADP(+) => D-xylulose + H(+) + NADPH


name: (E)-ferulate + UDP-alpha-D-glucose <=> 1-O-[(E)-feruloyl]-beta-D-glucose + UDP


name: AFG3L2 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Canis familiaris)


name: IL18:IL18R1 binds IL18RAP (Rattus norvegicus)


name: ERCC1:XPF cleaves flaps generated by SSA (Sus scrofa)


name: H2O + Met-enkephalin-Arg-Phe = L-arginyl-L-phenylalanine + Met-enkephalin


name: 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O => 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + 2 H(+) + phosphate


name: 5alpha-cholest-7-en-3-one + 2 H(+) + 3 NADPH + 3 O2 = (25S)-Delta7-dafachronate + 4 H2O + 3 NADP(+)


name: bis(myo-inositol) 1,3'-phosphate + 2 GDP-alpha-D-mannose => 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + 2 GDP + 2 H(+)


name: OSCAR binds collagen and SP-D (Homo sapiens)


name: 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA => 8 H(+) + malonamoyl-[OxyC ACP] + 8 malonyl-CoA


name: glycyl-L-leucine(out) + H(+)(out) = glycyl-L-leucine(in) + H(+)(in)


name: alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP-beta-L-fucose = a neolactoside IV(3)-alpha-Gal,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Gallus gallus)


name: 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H(+)


name: bPIX exchanges GTP for GDP on RAC, activating it (Homo sapiens)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Caenorhabditis elegans)


name: alpha-D-glucose + alpha-D-glucose 1-phosphate => alpha,alpha-trehalose + phosphate


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O => 1,2-dihexadecanoyl-sn-glycerol + phosphate


name: H2O + N-deacetylipecoside = dopamine + secologanin


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Dictyostelium discoideum)


name: The phagophore extends from the PIP3-enriched structure (Dictyostelium discoideum)


name: H(+) + malonyl-[ACP] + pentanoyl-CoA => 3-oxoheptanoyl-[ACP] + CO2 + CoA


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Canis familiaris)


name: (22R,23R)-22,23-dihydroxycampesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (22S)-22-hydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: POM121 binds the Nup107-Nup160 complex (Rattus norvegicus)


name: desmosterol + O2 + reduced [NADPH--hemoprotein reductase] => (24Z),26-hydroxydesmosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dab2 is recruited to the junctional plaques (Rattus norvegicus)


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Drosophila melanogaster)


name: 4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + ADP + H(+) + phosphate => 4-aminobutanoyl-[BtrI ACP] + ATP + L-glutamate


name: CDK1 phosphorylates LBR (Canis familiaris)


name: 1-hexadecanoyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + butanoate + H(+)


name: epothilone D + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> epothilone B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2-oxoglutarate + L-2-aminohexanoate = 2-oxohexanoate + L-glutamate


name: CYP2S1 4-hydroxylates atRA (Mus musculus)


name: (11Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate <=> 1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: Insulin receptor de-phosphorylation (Gallus gallus)


name: 3-oxosphinganine + docosanoyl-CoA => CoA + H(+) + N-docosanoyl-3-ketodihydrosphingosine


name: Sprouty sequesters CBL away from active EGFR (Homo sapiens)


name: Activated FGFR2:p-FRS bind to PPTN11 (Mus musculus)


name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 (Mus musculus)


name: eicosanoate + glycerol + H(+) => 1-eicosanoylglycerol + H2O


name: H(+) + L-valine <=> 2-methylpropan-1-amine + CO2


name: apigenin + UDP-alpha-D-glucose = apigenin 7-O-beta-D-glucoside + H(+) + UDP


name: PLK1 phosphorylates GTSE1 (Homo sapiens)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Xenopus tropicalis)


name: Formation of ORC(1-5) complex (Rattus norvegicus)


name: DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates


name: KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Bos taurus)


name: a fatty acid + an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: The phagophore extends from the PIP3-enriched structure (Bos taurus)


name: RAC1 and CDC42 activate PAK2 (Caenorhabditis elegans)


name: dodecanal + H2O + O2 => dodecanoate + H(+) + H2O2


name: RHOB binds effectors on endosomes (Caenorhabditis elegans)


name: SPRY2 is phosphorylated by phosphorylated MNK1 (Sus scrofa)


name: Unknown sepiapterin synthase transforms PTHP to sepiapterin (Homo sapiens)


name: a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+) => a very-long-chain 3-oxoacyl-CoA + H(+) + NADH


name: eicosanoyl-CoA + FAD + H(+) => (2E)-eicosenoyl-CoA + FADH2


name: an acyl phosphate + sn-glycerol 3-phosphate => a 1-acyl-sn-glycero-3-phosphate + phosphate


name: DOLPP1 dephosphorylates DOLDP to DOLP (Gallus gallus)