name: an archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate + H(+) + UDP => an archaeal dolichyl alpha-D-glucosyl phosphate + UDP-alpha-D-glucuronate


name: AFG3L2 binds mitochondrial inner membrane proteins (Xenopus tropicalis)


name: ORC6 is phosphorylated on T195 (Canis familiaris)


name: SUMOylation of NR1I2 with SUMO3 (Sus scrofa)


name: ATP + H2O + hexacosanoate(in) = ADP + H(+) + hexacosanoate(out) + phosphate


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Homo sapiens)


name: (1R,2S,4S)-neoisodihydrocarveol + NAD(+) = (1R,4S)-isodihydrocarvone + H(+) + NADH


name: dimethylallyl diphosphate + isoechinulin A => dehydroechinulin + diphosphate


name: (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H(+) + NADPH => (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+)


name: kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin (Homo sapiens)


name: natural killer cell lectin-like receptor binding


name: N(alpha)-methyl-L-histidine + S-adenosyl-L-methionine => H(+) + N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-homocysteine


name: butanal + FMN + 2 H(+) + H2O + sulfite => butane-1-sulfonate + FMNH2 + O2


name: 2-oxoglutarate + an N(1)-methyladenosine in mRNA + O2 = an adenosine in mRNA + CO2 + formaldehyde + succinate


name: Activation of ISG15 by UBA7 E1 ligase (Mus musculus)


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Gallus gallus)


name: phosphoadenylyl-sulfate reductase (thioredoxin) activity


name: 17alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + progesterone + reduced [NADPH--hemoprotein reductase]


name: Defective ADA does not deaminate (deoxy)adenosine (Homo sapiens)


name: Nephrin dimer:KIRREL binds FYN (Sus scrofa)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Drosophila melanogaster)


name: 2-oxoglutarate + an N(1)-ethyl-2'-deoxyadenosine in single-stranded DNA + O2 = a 2'-deoxyadenosine in single-stranded DNA + acetaldehyde + CO2 + H(+) + succinate


name: MSK1 activates ATF1 (Drosophila melanogaster)


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Bos taurus)


name: 17beta-estradiol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + testosterone


name: (S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-dichlorophenol + CO2 + pyruvate + succinate


name: acetyl-CoA + N-terminal L-methionyl-L-tyrosyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-tyrosyl-[protein]


name: SUCLG1/A2 cleaves succinyl-CoA (Dictyostelium discoideum)


name: fluoroacetyl-CoA + H2O <=> CoA + fluoroacetate + H(+)


name: BTRC binds p-S344, 347 NFE2L2 (Danio rerio)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH => 1-hexadecanoyl-2-(9-hydroxynonanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 = CO2 + grixazone B + 4 H2O


name: 26S proteasome degrades PolyUb-RUNX2 (Drosophila melanogaster)


name: H(+) + oxidized [electron-transfer flavoprotein] + propanoyl-CoA = acryloyl-CoA + reduced [electron-transfer flavoprotein]


name: Autocatalytic activation of MMP7 (Sus scrofa)


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Xenopus tropicalis)


name: CSNK1G2 phosphorylates p-CERT1-2 (Caenorhabditis elegans)


name: IL21 binds IL21R:JAK1 (Canis familiaris)


name: 3-oxohexacosanoyl-CoA + H(+) + NADH => (3R)-hydroxyhexacosanoyl-CoA + NAD(+)


name: (E)-hept-2-enal + H2O + NADP(+) = (E)-hept-2-enoate + 2 H(+) + NADPH


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Rattus norvegicus)


name: misfolded CFTR is degraded by the 26S proteasome (Homo sapiens)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Homo sapiens)


name: FUOM isomerises alpha-Fuc to beta-Fuc (Homo sapiens)


name: 2 beta-L-arabinofuranose => beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O


name: MARC1,MARC2 reduce N-hydroxylated compounds (Canis familiaris)


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H(+) + NADPH => (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphocholine <=> 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: 2-acyl LPI is acylated to PI by MBOAT7 (Sus scrofa)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Drosophila melanogaster)


name: 10-deoxymethynolide + 6 CO2 + 6 CoA + 2 H2O + 5 NADP(+) => 5 (S)-methylmalonyl-CoA + 11 H(+) + malonyl-CoA + 5 NADPH


name: ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA (Bos taurus)


name: Basigin binds Matrix metalloproteinase-1 (Mus musculus)


name: H2O + N-(9Z-octadecenoyl)-L-serine => (9Z)-octadecenoate + L-serine


name: EHMT1:EHMT2 methylates IL8 promoter (Drosophila melanogaster)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Xenopus tropicalis)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> (6E,10E)-geranyllinalool + diphosphate


name: oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor


name: NADP(+) + prostaglandin I2 = 15-dehydro-prostaglandin I2 + H(+) + NADPH


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Canis familiaris)


name: N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: Recruitment of Profilin by Ena/VASP proteins (Mus musculus)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 <=> (8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Bos taurus)


name: 3-oxopropanoate + H2O + NAD(+) => 2 H(+) + malonate + NADH


name: MTRR reduces cob(II)alamin to meCbl (Rattus norvegicus)


name: adenosylcob(III)inamide-GDP + alpha-ribazole => adenosylcob(III)alamin + GMP + H(+)


name: AKT phosphorylates FOXO3 downstream of ESR1 and EGFR (Rattus norvegicus)


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Danio rerio)


name: RHOC translocates to the endoplasmic reticulum membrane (Schizosaccharomyces pombe)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Caenorhabditis elegans)


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Dictyostelium discoideum)


name: (2R,3S)-piscidate + (E)-caffeoyl-CoA <=> cimicifugate D + CoA


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Sus scrofa)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Rattus norvegicus)


name: ITP(in) + UTP(out) => ITP(out) + UTP(in)


name: 6-carboxyhexanoyl-CoA + NAD(+) <=> 6-carboxyhex-2-enoyl-CoA + H(+) + NADH


name: Activation of RAC1 by VAV (Homo sapiens)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Dictyostelium discoideum)


name: BTNL9 binds immune cell surfaces (Canis familiaris)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Canis familiaris)


name: UCHL3, SENP8 cleave NEDD8 (Caenorhabditis elegans)


name: N-acetylserotonin + S-adenosyl-L-methionine => H(+) + melatonin + S-adenosyl-L-homocysteine


name: IL12B:IL12B translocates from ER lumen to the extracellular region (Sus scrofa)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Mus musculus)


name: H(+) + NADH + phosphate => H2O + NAD(+) + phosphonate


name: PLK1 phosphorylates FIRMM at S744 (Danio rerio)


name: kainate receptor binds glutamate (Sus scrofa)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Xenopus tropicalis)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Xenopus tropicalis)


name: (9Z,12Z,15Z)-octadecatrienamide + H2O = (9Z,12Z,15Z)-octadecatrienoate + NH4(+)


name: MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine


name: geranylgeranyl diphosphate = beta-araneosene + diphosphate


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Homo sapiens)


name: S-methyl-5-thio-alpha-D-ribose 1-phosphate => S-methyl-5-thio-D-ribulose 1-phosphate


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Xenopus tropicalis)


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Mus musculus)


name: Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) (Sus scrofa)


name: [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + O2 => glycine betaine + 2 H(+) + phosphate


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Saccharomyces cerevisiae)


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Saccharomyces cerevisiae)


name: 4-hydroxy-6-(13-methyl-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA => 12-methyloctadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: H(+) + hnu + octadecanoate = CO2 + heptadecane


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Rattus norvegicus)


name: 2 glutathione + O2 <=> glutathione disulfide + H2O2


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Caenorhabditis elegans)


name: (12Z)-10-hydroxyoctadecenoate + H2O <=> 10,13-dihydroxyoctadecanoate


name: L-dopa(out) + L-phenylalanine(in) <=> L-dopa(in) + L-phenylalanine(out)


name: Intrinsic nucleotide exchange on RAS (Danio rerio)


name: (2E)-dodecenal + H(+) + NADPH => dodecanal + NADP(+)


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol <=> 1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: PSAP gets cleaved (Caenorhabditis elegans)


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Homo sapiens)


name: N-octanoyl-(2S)-hydroxyglycine <=> glyoxylate + octanamide


name: RUNX3:CBFB binds the ITGAL gene,(ITGA4 gene) promoter (Homo sapiens)


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)


name: SCUBE1, SCUBE3 oligomerize (Plasmodium falciparum)


name: propanoate + succinyl-CoA => propanoyl-CoA + succinate


name: Release of GABA at the synapse (Mus musculus)


name: deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Drosophila melanogaster)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H(+) + NADPH


name: Phosphorylated STAT1, STAT3 form dimers (Homo sapiens)


name: Activation of Latent HCMV Genome (Homo sapiens)


name: ATP + Fe(III)-petrobactin(out) + H2O <=> ADP + Fe(III)-petrobactin(in) + H(+) + phosphate


name: H2O + S-ethyl-L-cysteine <=> ethanethiol + NH4(+) + pyruvate


name: AMP + diphosphate + L-seryl-[peptidyl-carrier protein] => ATP + holo-[peptidyl-carrier protein] + L-serine


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine-phospho-ribonucleoside in mRNA + H2O = (N(7)-methyl 5'-triphospho-guanosine)-guanosine + a 5'-end phospho-ribonucleoside in mRNA + H(+)


name: CD28 homodimer binds B7-2 monomer (Bos taurus)


name: Caspase-1 active tetramer formation (Rattus norvegicus)


name: all-trans-retinol + H(+) + hexadecanoate => all-trans-retinyl hexadecanoate + H2O


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: PXLP-K56-SRR dimer deaminates D-Ser (Bos taurus)


name: CYP19A1 hydroxylates ANDST to E1 (Rattus norvegicus)


name: 2'-aminobiphenyl-2,3-diol + NAD(+) => 9H-carbazole + H(+) + NADH + O2


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Xenopus tropicalis)


name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Bos taurus)


name: prostaglandin E2(out) => prostaglandin E2(in)


name: single base insertion or deletion binding


name: Formation of Cyclin E:Cdk2 complexes (Drosophila melanogaster)


name: acetyl-CoA + cyathin A3 = 11-O-acetylcyathin A3 + CoA


name: ATP + H2O + prostaglandin E1(in) <=> ADP + H(+) + phosphate + prostaglandin E1(out)


name: LIG1 bound to POLB ligates SSB (Mus musculus)


name: Casein kinase II phosphorylates PTEN (Mus musculus)


name: (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] => (2S)-dihydrotricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Caspase-mediated cleavage of occludin (Homo sapiens)


name: diiodine + 2 H2O => 2 H(+) + H2O2 + 2 iodide


name: Formation of MSH1:PMS2 Complex (Caenorhabditis elegans)


name: 3-(methylsulfanyl)propanoyl-CoA + AMP + diphosphate => 3-(methylsulfanyl)propanoate + ATP + CoA


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Mus musculus)


name: bPIX exchanges GTP for GDP on RAC, activating it (Mus musculus)


name: SRD5A3 dehydrogenates TEST to DHTEST (Plasmodium falciparum)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH


name: BRD7 promotes EP300-mediated acetylation of TP53 (Sus scrofa)


name: RAB5 and GAPVD1 bind AP-2 (Rattus norvegicus)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Homo sapiens)


name: futalosine + H2O => dehypoxanthine futalosine + hypoxanthine


name: a triacylglycerol + all-trans-retinol <=> a 1,3-diacylglycerol + an all-trans-retinyl ester


name: Interaction of Bcl10 to CARMA1 (Homo sapiens)


name: 8'-apo-beta-carotenol + O2 = (3E,5E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Saccharomyces cerevisiae)


name: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD(+) => 6-oxocyclohex-1-ene-1-carbonyl-CoA + H(+) + NADH


name: ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 (Bos taurus)


name: Prolactin receptor is internalized (Sus scrofa)


name: 3-methylundecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: NPHP4 protein binds LATS proteins (Sus scrofa)


name: FMN + formaldehyde + 2 H(+) + H2O + methanesulfinate => dimethyl sulfone + FMNH2 + O2


name: acetoacetate + acetyl-CoA => acetate + acetoacetyl-CoA


name: PNPLA5 hydrolyzes TAG (Caenorhabditis elegans)


name: (24S)-7alpha-dihydroxycholesterol + NAD(+) = (24S)-7alpha,24-dihydroxycholest-4-en-3-one + H(+) + NADH


name: Defective CYP11B2 does not oxidise 11DCORST (Homo sapiens)


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Bos taurus)


name: structural constituent of chitin-based cuticle


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Rattus norvegicus)


name: ATP + D-ribose 5-phosphate + H(+) => ADP-D-ribose + diphosphate


name: betaine aldehyde + H2O + NAD(+) => glycine betaine + 2 H(+) + NADH


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Canis familiaris)


name: estrone + UDP-alpha-D-glucuronate = estrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: Keratin filament formation (Rattus norvegicus)


name: Recruitment of POLB to oxidatively damaged AP site (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: DSPG and CSPG translocate to the lysosome for degradation (Sus scrofa)


name: L-lysyl-[lipoyl-carrier protein] + N(6)-[(R)-dihydrolipoyl]-5'-AMP = AMP + 2 H(+) + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein]


name: (E)-isoeugenol + O2 = acetaldehyde + vanillin


name: (E)-cinnamoyl-CoA + AMP + diphosphate => (E)-cinnamate + ATP + CoA


name: MAOB:FAD oxidatively deaminates TYR (Dictyostelium discoideum)


name: The Ligand:GPCR:G12/13 complex dissociates (Drosophila melanogaster)


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Homo sapiens)


name: ORC1 translocates to the nucleus (Schizosaccharomyces pombe)


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Mus musculus)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Rattus norvegicus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Bos taurus)


name: SUMOylation of MDC1 with SUMO1 (Mus musculus)


name: H2O + O-phospho-L-homoserine <=> L-threonine + phosphate


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA => (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA + H2O


name: CFTR transports Cl- from cytosol to extracellular region (Sus scrofa)


name: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively (Sus scrofa)


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Bos taurus)


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-corvol ether B + diphosphate


name: ABCB1 transports PREDN,PREDL out of hepatic cells (Dictyostelium discoideum)


name: SREBP1A,1C,2 binds SCAP:INSIG:oxysterol and is retained in the endoplasmic reticulum (Homo sapiens)


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Homo sapiens)


name: dopamine neurotransmitter receptor activity, coupled via Gi/Go


name: 2 Na(+)(out) + tauroallocholate(out) => 2 Na(+)(in) + tauroallocholate(in)


name: 5'-dehydroadenosine + H2O + O2 = 9-riburonosyladenine + H(+) + H2O2


name: 3-oxododecanedioyl-CoA + CoA => acetyl-CoA + decanedioyl-CoA


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 <=> 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O


name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Rattus norvegicus)


name: 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine => L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine


name: H2O + N-tetradecanoylsphing-4-enine => sphing-4-enine + tetradecanoate


name: ERK1/2/5 activate RSK1/2/3 (Rattus norvegicus)


name: Some HSPGs are secreted to the plasma membrane (Drosophila melanogaster)


name: hercynine + L-cysteine + O2 = H2O + S-(hercyn-2-yl)-L-cysteine S-oxide


name: Formation of ORC(2-5) complex (Rattus norvegicus)


name: beta-nicotinamide D-ribonucleotide + H2O = NH4(+) + nicotinate beta-D-ribonucleotide


name: ADO oxidises 2AET to HTAU (Caenorhabditis elegans)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Canis familiaris)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Schizosaccharomyces pombe)


name: CoA + ethyl acetate => acetyl-CoA + ethanol


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)


name: Insulin binds the insulin receptor (Danio rerio)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Sus scrofa)


name: RUNX3 binds TEADs and YAP1 (Caenorhabditis elegans)


name: Ethylene is oxidized to Ethylene oxide by CYP1A1 (Bos taurus)


name: CaMKII autophosphorylates (Homo sapiens)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Plasmodium falciparum)


name: MTMR14, MTMR3 dephosphorylate PI3P (Xenopus tropicalis)


name: RHOF binds effectors at the plasma membrane (Caenorhabditis elegans)


name: a 1-acyl-sn-glycero-3-phosphate + a fatty acyl-[ACP] => a 1,2-diacyl-sn-glycero-3-phosphate + holo-[ACP]


name: [protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide => [protein]-dithiol + 2 AH2 + H(+) + sulfite


name: Transport of L1 into endosomes (Drosophila melanogaster)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + 2 glutathione <=> (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: poly-ADP-D-ribose modification-dependent protein binding


name: 2-hexyl-5-(5-hydroxypentyl)resorcinol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-hexyl-5-pentylresorcinol + O2 + reduced [NADPH--hemoprotein reductase]


name: Interaction of Tie2 with Ang1 (Homo sapiens)


name: 5'-deoxyadenosine + [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + A + H(+) + L-methionine => [mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + AH2 + S-adenosyl-L-methionine


name: RAC2 GEFs activate RAC2 (Xenopus tropicalis)


name: UVSSA:USP7 deubiquitinates ERCC6 (Bos taurus)


name: Resumption of elongation after recovery from pausing (Xenopus tropicalis)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Dictyostelium discoideum)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Saccharomyces cerevisiae)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: Formation of FACT complex (Caenorhabditis elegans)


name: sphinga-(4E,8Z)-dienine + tetracosanoyl-CoA <=> CoA + H(+) + N-tetracosanoylsphinga-(4E,8Z)-dienine


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 (Sus scrofa)


name: ILK interacts with beta-1 integrin (Canis familiaris)


name: 4 monapinone A + O2 = 2 dinapinone A + 2 H2O


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Bos taurus)


name: p-T182 MAPKAPK5 phosphorylates FOXO3 (Mus musculus)


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH = a long-chain fatty acyl-CoA + n CO2 + n CoA + H2O + 2n NADP(+)


name: LRRC16A binds F-actin capping protein (Bos taurus)


name: ATP + S-sulfanyl-L-cysteine + tRNA(Cys) = (S)-sulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Mus musculus)


name: (S)-scoulerine + S-adenosyl-L-methionine = (S)-tetrahydrocolumbamine + H(+) + S-adenosyl-L-homocysteine


name: SHC1 in the RET complex is phosphorylated (Xenopus tropicalis)


name: p-Y7-CLEC1B dimer:PDPN binds SYK (Canis familiaris)


name: Transport of MHC heterotrimer to ER exit site (Bos taurus)


name: ALOX5 oxidises 15S-HpETE to LXA4/B4 (Homo sapiens)


name: DSCAM/DSCAML1 homodimerization (Bos taurus)


name: CXCL12 gene expression is stimulated by ERBB4s80:ESR1:estrogen (Homo sapiens)


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Bos taurus)


name: glycine + hexadecanoyl-CoA = CoA + H(+) + N-hexadecanoylglycine


name: 2 Na(+)(out) + taurodeoxycholate(out) => 2 Na(+)(in) + taurodeoxycholate(in)


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Homo sapiens)


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Rattus norvegicus)


name: D-phenylalanyl-tRNA(Phe) + H2O <=> D-phenylalanine + H(+) + tRNA(Phe)


name: USP13 deubiquitinates BECN1,USP10 (Rattus norvegicus)


name: 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoserine + H2O => (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphoserine + H(+)


name: RET binds GFRA1,GFRA2 (Canis familiaris)


name: SCF(SKP2) polyubiquitinates RUNX2 (Drosophila melanogaster)


name: L-alanine + L-cysteine => H2O + L-alanyl-L-cysteine


name: Activated FGFR4 binds PLCG1 (Mus musculus)


name: Association of GABA B receptor with G protein beta-gamma subunits (Drosophila melanogaster)


name: RGGT:CHM binds RABs (Drosophila melanogaster)


name: triphosphoric monoester hydrolase activity


name: 26S proteasome processes p-7S-p100:RELB to form p52:RELB (Canis familiaris)


name: SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Danio rerio)


name: PTP-RO interacts with p-c-Kit complex (Danio rerio)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] => 4-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: JAK1-mediated phosphorylation of RAF1 (Homo sapiens)


name: Exocytosis of ficolin-rich granule membrane proteins (Xenopus tropicalis)


name: MEN1 binds MLL2 complex (Rattus norvegicus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate <=> 7-epi-sesquithujene + diphosphate


name: SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors (Homo sapiens)


name: p-4Y-SIRPA:CD47:SKAP2 binds FYB (Sus scrofa)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Danio rerio)


name: Type XII and XIV collagens associate with type I and type II fibrils. (Rattus norvegicus)


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Canis familiaris)


name: PGRMC2:Hemes translocate to the nucleus (Homo sapiens)


name: eIF5B:GTP is hydrolyzed and released (Gallus gallus)


name: a (3R)-3-isocyanyl-fatty acid + ATP + holo-[ACP] <=> a (3R)-3-isocyanyl-fatty acyl-[ACP] + AMP + diphosphate


name: Monoubiquitinated PTEN translocates to the nucleus (Danio rerio)


name: cytidine(56) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(56) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: (6Z,9Z,12Z)-octadecatrienoate + H2O <=> (10S)-hydroxy-(6Z,12Z)-octadecadienoate


name: 5alpha-cholesta-7,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 7-dehydrodesmosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate + [(1->4)-alpha-D-galacturonosyl](n-2) => [(1->4)-alpha-D-galacturonosyl](n)


name: quercitrin + UDP-beta-L-rhamnose => H(+) + quercetin 3,7-bis-O-alpha-L-rhamnoside + UDP


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose => alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP + H(+)


name: EFNB:GRB4 binds GIT1 (Drosophila melanogaster)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Rattus norvegicus)


name: TTR:RBP:atROL binds to STRA6 receptor (Bos taurus)


name: Phosphorylation of complexed TSC2 by PKB (Schizosaccharomyces pombe)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)


name: 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(+) + NADPH = 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADP(+)


name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Xenopus tropicalis)


name: NR2E1 associated with transcription repressors binds PTEN promoter (Homo sapiens)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Gallus gallus)


name: RIPK1 is cleaved by CASP8:FLIP(L) (Sus scrofa)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Drosophila melanogaster)


name: Dimerization of Tie2/Ang1 complex (Mus musculus)


name: ADRM1:26S proteaseome binds UCHL5 (Caenorhabditis elegans)


name: p-S225-SPHK1 localizes to cytosol (Dictyostelium discoideum)


name: hexadecanoyl-CoA + L-cysteinyl-[protein] => CoA + S-hexadecanoyl-L-cysteinyl-[protein]


name: H(+) + N,N-dihydroxy-L-phenylalanine = (E)-phenylacetaldehyde oxime + CO2 + H2O


name: ATP + L-amino acyl-L-cysteinyl-[protein] = (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + ADP + H(+) + phosphate


name: PLK1 binds phosphorylated condensin II complex (Rattus norvegicus)


name: (10bR,4aS)-noroxomaritidine + H(+) + NADPH <=> (10bR,4aS)-oxomaritidine + NADP(+)


name: ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => ent-cassa-12,15-dien-2-one + O2 + reduced [NADPH--hemoprotein reductase]


name: dGTP + methylglyoxal => N(2)-(1-hydroxy-2-oxopropyl)-dGTP


name: Phosphorylation of Chk1 by ATR (Gallus gallus)


name: The exocyst complex binds to RAB3IP in the ciliary targeting complex (Sus scrofa)


name: cholest-4-en-3-one + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> (25S)-3-oxocholest-4-en-26-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Fibulin binds elastic fibres (Mus musculus)


name: H(+) + L-ornithine + NADPH + pyruvate => H2O + N(5)-[1(S)-1-carboxyethyl]-L-ornithine + NADP(+)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2 <=> (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanedioate + H(+) + H2O2


name: Lactoferrin scavenges iron ions (Drosophila melanogaster)


name: WT1, NR5A1 (SF1), GATA4, ZFPM2 bind the SRY gene (Homo sapiens)


name: NUMB:ITCH bind and ubiquitnate GLI1 (Sus scrofa)


name: tBID binds to inactive BAK protein (Rattus norvegicus)


name: CREB3L4 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Homo sapiens)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Canis familiaris)


name: PIAS1,3 SUMOylate MBD1 with SUMO1 (Mus musculus)


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-pyrethrolone <=> CoA + pyrethrin I


name: CYP4F22 20-hydroxylates TrXA3 (Homo sapiens)


name: TLR processing at low pH (Canis familiaris)


name: 6-oxocineole + H(+) + NADH => 2-exo-hydroxy-1,8-cineole + NAD(+)


name: dimethylallyl diphosphate + L-tryptophan <=> 7-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Gallus gallus)


name: ATP + butanoate + H(+) + NADPH = AMP + butanal + diphosphate + NADP(+)


name: (2Z,6E)-farnesyl diphosphate <=> (-)-gamma-cadinene + diphosphate


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Xenopus tropicalis)


name: acrolein + spermidine => spermine monoaldehyde


name: L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine


name: 3-methylsulfanylpropanal + CO2 => 4-methylsulfanyl-2-oxobutanoate + H(+)


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Rattus norvegicus)


name: GTP + IMP + L-aspartate => GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate


name: CDP-2,3-bis-O-(phytanyl)-sn-glycerol + L-serine = 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine + CMP + H(+)


name: ferruginol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + sugiol


name: [Rab1 protein]-L-serine + H(+) + phosphocholine => [Rab1 protein]-O-phosphocholine-L-serine + H2O


name: COPII coat binds TRAPPCII and RAB1:GDP (Rattus norvegicus)


name: RHOD translocates to the Golgi membrane (Canis familiaris)


name: fumonisin B1 + 2 H2O = (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + 2 H(+) + 2 tricarballylate


name: itaconate + L-cysteinyl-[protein] = S-(2,3-dicarboxypropyl)-L-cysteinyl-[protein]


name: DNA-binding transcription repressor activity, RNA polymerase II-specific


name: SEMA5A binds to PLXNB3 (Rattus norvegicus)


name: an N-acyl-aromatic L-alpha-amino acid + H2O = a carboxylate + an aromatic L-alpha-amino acid


name: 4 AH2 + all-trans-4,4'-diapolycopene + 4 O2 => 4 A + all-trans-4,4'-diapolycopene-4,4'-dial + 6 H2O


name: ADP + H(+) + phosphate + protoporphyrin IX(out) => ATP + H2O + protoporphyrin IX(in)


name: 1-octadecanoyl 2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-[(9Z)-octadecenoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Xenopus tropicalis)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Gallus gallus)


name: 2 H(+) + isoproturon + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 1-methyl-3-[4-(propan-2-yl)phenyl]urea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PTPN3 binds p-T183,Y185 MAPK12 (Xenopus tropicalis)


name: Cytosolic DUSPs dephosphorylate MAPKs (Plasmodium falciparum)


name: 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase]


name: APC/C:Cdh1-mediated degradation of Skp2 (Canis familiaris)


name: DBC1 is phosphorylated by ATM/ART (Homo sapiens)


name: Thrombin-activated PARs activate Gq (Gallus gallus)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate => 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate


name: acetyl-CoA + 8 H(+) + holo-[ACP] + 8 malonyl-CoA = 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + 8 CO2 + 9 CoA + 2 H2O


name: ATP + L-tryptophan + tRNA(Trp) => AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)


name: (9Z,12Z)-octadecadienoyl-CoA + H(+) + malonyl-CoA <=> (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 2-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Sus scrofa)


name: chloride(out) + L-valine(out) + 2 Na(+)(out) <=> chloride(in) + L-valine(in) + 2 Na(+)(in)


name: JET binds phosphorylated nuclear TIM, facilitating its ubiquitination (Drosophila melanogaster)


name: a nucleoside 3'-phosphate + H(+) => a nucleoside 2',3'-cyclic phosphate + H2O


name: 2 (2E,6E)-farnesyl diphosphate + H(+) + NADPH => 2 diphosphate + NADP(+) + squalene


name: african-3-ene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + germacrene D


name: p-Y420-FYN is phosphorylated on S21 (Mus musculus)


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Rattus norvegicus)


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Sus scrofa)


name: 3-oxosphinganine + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoyl-3-oxosphinganine


name: MRSBs reduce L-methyl-(R)-S-oxide to L-methionine (Canis familiaris)


name: MUS81:EME1,EME2 cleaves D-loop (Homo sapiens)


name: all-trans-violaxanthin + 2 L-ascorbate <=> all-trans-zeaxanthin + 2 H2O + 2 L-dehydroascorbate


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Bos taurus)


name: A + D-proline <=> 1-pyrroline-2-carboxylate + AH2


name: (R)-2-hydroxyglutarate + acetoacetate => (S)-3-hydroxybutanoate + 2-oxoglutarate


name: Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Homo sapiens)


name: choline + H(+) + sulfate => choline sulfate + H2O


name: D-xylotetraose + O2 => D-xylotetraono-1,5-lactone + H2O2


name: ABC-type oligogalacturonide transporter activity


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Mus musculus)


name: Integrase binds viral DNA ends (Homo sapiens)


name: Active G alpha (q) binds RGS proteins (Caenorhabditis elegans)


name: (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecenyl)-glycerol <=> 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: 5-phosphomethyl-dUMP in DNA + L-serine <=> 5-O-(L-seryl)-dTMP in DNA + phosphate


name: ATP + CoA + nonanoate => AMP + diphosphate + nonanoyl-CoA


name: (-)-beta-santalene + diphosphate => (2E,6E)-farnesyl diphosphate


name: FOXO1,FOXO3 binds CAV1 gene promoter (Homo sapiens)


name: Activated TP receptor binds G-protein  G13 (Drosophila melanogaster)


name: Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Canis familiaris)


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Plasmodium falciparum)


name: 2-oxoglutarate + AH2 + fumitremorgin B + 2 O2 = A + CO2 + H2O + succinate + verruculogen


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA => [N,O(9)-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: OPTN binds polyUb-RIPK1 within the TNFR1 complex (Sus scrofa)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Saccharomyces cerevisiae)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Danio rerio)


name: Autoglucosylation of GYG2 complexed with GYS2-b (Sus scrofa)


name: ARHGAP35 stimulates RHOA GTPase activity (Homo sapiens)


name: CYTH proteins bind ARF1:GTP (Gallus gallus)


name: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP


name: 1,7-dimethylxanthine + H(+) + NADH + O2 = 7-methylxanthine + formaldehyde + H2O + NAD(+)


name: Activated FGFR4 phosphorylates PPTN11 (Homo sapiens)


name: MRE11 binds cytosolic DNA (Caenorhabditis elegans)


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Xenopus tropicalis)


name: Interaction of KIT and sSCF (Danio rerio)


name: TYSND1 cleaves TYSND1 (Canis familiaris)


name: (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + O2 + reduced [NADPH--hemoprotein reductase]


name: Caspase-mediated cleavage of Tau (Mus musculus)


name: 2-methylpropanoyl-CoA + H2O = 2-methylpropanoate + CoA + H(+)


name: USP17 deubiquitinates SUDS3 (Rattus norvegicus)


name: an N-acylsphinganine + H2O => a fatty acid + sphinganine


name: PGAM5 dodecamer dephosphorylates p-S336-ME1 (Canis familiaris)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Canis familiaris)


name: H2O + L-arginine + NAD(+) => 5-guanidino-2-oxopentanoate + H(+) + NADH + NH4(+)


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = an anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] + CoA + H(+)


name: FADH2 + O2 + styrene => (S)-styrene oxide + FAD + H(+) + H2O


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: inulobiose => bis-D-fructose 2',1:2,1'-dianhydride + H2O


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + H2O => (9Z)-hexadecenoate + 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + H(+)


name: (R)-vicianin + H2O = mandelonitrile + vicianose


name: Galanin receptors can bind galanin (Homo sapiens)


name: ATP + glycyl-L-proline(out) + H2O => ADP + glycyl-L-proline(in) + H(+) + phosphate


name: H2O + NADP(+) + vanillin = 2 H(+) + NADPH + vanillate


name: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate


name: SMURF1 binds phosphorylated PARD6A (Canis familiaris)


name: YME1L1 proteolyzes unassembled proSMDT1 (Homo sapiens)


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Xenopus tropicalis)


name: 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA (Homo sapiens)


name: isoxazolin-5-one + O-acetyl-L-serine = 3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate + H(+)


name: a 3',5'-unsubstituted flavanone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => a 3',5'-dihydroxyflavanone + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Association of procollagen type XV (Canis familiaris)


name: (2R)-2-phosphoglycerate + H2O => (R)-glycerate + phosphate


name: Co(I)-[dimethylamine-specific corrinoid protein] + dimethylamine + H(+) => methyl-Co(III)-[dimethylamine-specific corrinoid protein] + methylamine


name: an NDP-alpha-D-glucose + D-glucose = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H(+)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Sus scrofa)


name: HS-GAGs translocate to the lysosome for degradation (Sus scrofa)


name: dimethyl sulfoxide + H2O + NAD(+) => dimethyl sulfone + H(+) + NADH


name: Expression of ABCG5 regulated by NR1H2,3 (Homo sapiens)


name: 4-O-demethylbarbatate + S-adenosyl-L-methionine <=> proatranorin I + S-adenosyl-L-homocysteine


name: p62 is recruited and forms a complex with TRAF6 (Danio rerio)


name: PI3K synthesizes PIP3 downstream of ALK (Mus musculus)


name: ARF1:GTP binds Golgin TRIP11 (Rattus norvegicus)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Sus scrofa)


name: L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: GTSE1 binds microtubule lattice in interphase cells (Sus scrofa)


name: EHD proteins interact with Rabenosyn-5 (Canis familiaris)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Gallus gallus)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Bos taurus)


name: alpha-D-ribose 1,5-bisphosphate + ATP <=> 5-phospho-alpha-D-ribose 1-diphosphate + ADP


name: mito-STARD7 transports Q10 to outer mitochondrial membrane (Bos taurus)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H(+)


name: NTRK3 binds GRB2:SOS1 through SHC1 (Homo sapiens)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Mus musculus)


name: Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Bos taurus)


name: D-mannose 6-phosphate + H2O + phosphoenolpyruvate => 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate


name: PTGFR binds PTGFR agonists (Danio rerio)


name: OCT1 transports organic cations into hepatic cells (Mus musculus)


name: Type XII and XIV collagens associate with type I and type II fibrils. (Xenopus tropicalis)


name: an N-(fatty acyl)-L-tyrosine + H2O => a fatty acid + L-tyrosine


name: acrolein + hydrogen cyanide = (2S)-2-hydroxybut-3-enenitrile


name: acetyl-CoA + vanillin => 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA


name: Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it (Sus scrofa)


name: p-S225-SPHK1 localizes to cytosol (Canis familiaris)


name: 1-acyl LPC is acylated to PC by LPCAT (Bos taurus)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] => 6alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: all-trans-nonaprenyl diphosphate + H(+) + homogentisate = 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate


name: glyoxylate + H2O + propanoyl-CoA = 3-methylmalate + CoA + H(+)


name: Caspase-mediated cleavage of Tau (Sus scrofa)


name: ATP + NH4(+) + UTP => ADP + CTP + 2 H(+) + phosphate


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-choline = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: 5-aminopentanoate + NH4(+) => 5-aminopentanamide + H2O


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + NADP(+) => (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + NADPH


name: (3S,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol = (+)-medicarpin + H2O


name: Necl-1:Necl-2 trans heterodimer interaction (Sus scrofa)


name: Soluble PROCR binds PRTN3:CD177 (Rattus norvegicus)


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Sus scrofa)


name: [(1->3)-beta-D-glucosyl](n) + phosphate => [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: Tryptophan is hydroxylated (Rattus norvegicus)


name: (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate => (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2


name: KLK5 cleaves and activates KLK8 (Bos taurus)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Danio rerio)


name: acetylsalicylate + L-lysyl-[protein] = H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate


name: HMOX1 translocates from the cytosol to the nucleoplasm (Bos taurus)


name: PTPN3 dephosphorylates MAPK12 (Homo sapiens)


name: FUT3 transfers Fuc to Type 1 DSGG to form dsLeA (Canis familiaris)


name: succinylCoA + GDP + Pi <=> succinate + CoASH + GTP (Gallus gallus)


name: 2 3-phenylpyruvate + H(+) => H2O + phenguignardate


name: glutamine + H2O => glutamate + NH4+ [GLS] (Gallus gallus)


name: Phosphorylation of CD28 (Xenopus tropicalis)


name: Discoidal HDL binds membrane-associated free cholesterol (Bos taurus)


name: DUOX1,2 reduce O2 to H2O2 (Rattus norvegicus)


name: H(+) + steviolmonoside + UDP => steviol + UDP-alpha-D-glucose


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Canis familiaris)


name: KIR2DS2 interacting with HLA-C group 1 (Cw3) (Mus musculus)


name: 9,10-epoxy-(12Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-9,10-epoxy-(12Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p-Y701-STAT1 binds p-Y705-STAT3 (Drosophila melanogaster)


name: double-stranded DNA exodeoxyribonuclease activity


name: p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 (Mus musculus)


name: a 5-hydroxy anthocyanidin + UDP-alpha-D-glucose = an anthocyanin 5-O-beta-D-glucoside + H(+) + UDP


name: HSF1 trimer binds HSE on the target gene (Homo sapiens)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Canis familiaris)


name: Formation of anchoring fibrils (Mus musculus)


name: PTPRJ dephosphorylates MET (Rattus norvegicus)


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Sus scrofa)


name: H2O + nicotinate beta-D-ribonucleotide => beta-D-ribosylnicotinate + phosphate


name: cytidine(1400) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1400) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: FUT1,2 transfer fucose to gangliosides (Canis familiaris)


name: 3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine = 3',4,7-trihydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: dihydrosterigmatocystin + S-adenosyl-L-methionine = 8-O-methyldihydrosterigmatocystin + H(+) + S-adenosyl-L-homocysteine


name: RHOF auto-activates (Caenorhabditis elegans)


name: diphosphate + GMP = 5-phospho-alpha-D-ribose 1-diphosphate + guanine


name: CoA + H(+) + O-acyltropine => an acyl-CoA + tropine


name: 3,3'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine => isorhamnetin + S-adenosyl-L-methionine


name: 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + H(+) + NADH => (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + NAD(+)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Gallus gallus)


name: New CENPA-containing nucleosomes are deposited at the centromere (Homo sapiens)


name: RAC1 binds PAK1-3 (Drosophila melanogaster)


name: ULK3:SUFU dissociates (Drosophila melanogaster)


name: TXN2 binds CysS248-MPST (Xenopus tropicalis)


name: MAP2K2 binds MAPK1 (Saccharomyces cerevisiae)


name: Addition of galactose to Core 6 glycoprotein (Rattus norvegicus)


name: PRODH oxidises L-Pro to 1PYR-5COOH (Schizosaccharomyces pombe)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Mus musculus)


name: Viral inhibitor of caspase-8 activation (UL36) binds caspase-8 (Homo sapiens)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Rattus norvegicus)


name: a ganglioside GT1a (d18:1(4E)) + CMP + H(+) => a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: (9Z)-octadecenoyl-CoA + 1-decanoylglycerol <=> 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: phycoerythrobilin-L-cysteinyl(84)-[C-phycoerythrin beta-subunit] <=> (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[C-phycoerythrin beta-subunit]


name: (-)-5-epi-eremophilene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Interleukin-2 receptor alpha binds interleukin-2 (Canis familiaris)


name: H2O + prostaglandin E2 1-glyceryl ester <=> glycerol + H(+) + prostaglandin E2


name: 2-methyl-cis-aconitate + H2O => 3-hydroxybutane-1,2,3-tricarboxylate


name: (9Z)-hexadecenoyl-CoA + [Wnt protein]-L-serine => [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + CoA


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 5'-deoxyadenosine + 8-methyladenosine(2503) in 23S rRNA + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,2,3,5-tetrahydroxybenzene + 1,3,5-trihydroxybenzene


name: WLS dissociates from retromer (Drosophila melanogaster)


name: Phosphorylation of USP8 by P-AKT (Dictyostelium discoideum)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Rattus norvegicus)


name: A + a 3-oxosteroid = a 3-oxo-Delta(1)-steroid + AH2


name: AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] => 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase]


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)


name: Exocytosis of ficolin-rich granule lumen proteins (Saccharomyces cerevisiae)


name: (R)-glycerate + ATP = (2R)-2-phosphoglycerate + ADP + H(+)


name: Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR recruit GRB2:SOS1 through SHC1  (Homo sapiens)


name: AH2 + S-adenosyl-L-methionine + UTP = 3'-deoxy-3',4'-didehydro-UTP + 5'-deoxyadenosine + A + H(+) + H2O + L-methionine


name: 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + NADP(+)


name: 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA <=> 3-oxopropanoyl-CoA + methanethiol


name: Follitropin is a heterodimer (Gallus gallus)


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Canis familiaris)


name: Integrator complex processes the 3' end of snRNA (Canis familiaris)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Caenorhabditis elegans)


name: 5,10-methylenetetrahydromethanopterin + NAD(+) <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Schizosaccharomyces pombe)


name: 3 H2O + hydrogen sulfide + 3 NADP(+) => 4 H(+) + 3 NADPH + sulfite


name: Displacement of TDG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate <=> allo-aromadendrene + diphosphate


name: RNF8 and RNF168 ubiquitinate H2AFX (Canis familiaris)


name: a quinone + D-glucose => a quinol + D-glucono-1,5-lactone


name: AMP + diphosphate + H(+) + L-glutamate + NAD(+) => ATP + deamido-NAD(+) + H2O + L-glutamine


name: SARS-CoV-2 nsp3 deISGylates ISGylated IFIH1 (Homo sapiens)


name: LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) (Homo sapiens)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Drosophila melanogaster)


name: 2 (S)-lactate(out) + thromboxane B2(in) => 2 (S)-lactate(in) + thromboxane B2(out)


name: Caspase-mediated cleavage of Lamin A (Xenopus tropicalis)


name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate (Homo sapiens)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Bos taurus)


name: NPAS4 stimulates RET gene expression (Homo sapiens)


name: 3-oxo-(11Z)-hexadecenoyl-CoA + CO2 + CoA => (9Z)-tetradecenoyl-CoA + H(+) + malonyl-CoA


name: 3xPPCDC:3FMN decarboxylates PPC (Canis familiaris)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Mus musculus)


name: tBID binds to inactive BAX protein (Mus musculus)


name: ATP + H2O + sphing-4-enine(in) => ADP + H(+) + phosphate + sphing-4-enine(out)


name: ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE (Xenopus tropicalis)


name: estrone 3-sulfate(out) + n H(+)(out) => estrone 3-sulfate(in) + n H(+)(in)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Sus scrofa)


name: L-galactonate + NAD(+) => H(+) + keto-D-tagaturonate + NADH


name: 8-chloroquinolin-2(1H)-one + AH2 => 8-chloroquinoline + A + H2O


name: [(1->2)-beta-D-mannosyl](n+1) + GDP + H(+) => [(1->2)-beta-D-mannosyl](n) + GDP-alpha-D-mannose


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Mus musculus)


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Bos taurus)


name: PPP1R3C binds to glycogen:GYG1:GYS1 (Drosophila melanogaster)


name: 9alpha-copalyl diphosphate = diphosphate + stemod-13(17)-ene


name: SEC31:SEC13 and v-SNARE recruitment (Saccharomyces cerevisiae)


name: GTP + H2O => 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Bos taurus)


name: agmatine + benzoate => H2O + N(4)-benzoylagmatine


name: acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) <=> CO + CoA + methyl-Co(III)-[corrinoid Fe-S protein]


name: GRIK3 homomer binds glutamate (Homo sapiens)


name: Caspase cleavage of UNC5A (Homo sapiens)


name: PGM1:Mg2+ isomerises G6P to G1P (Dictyostelium discoideum)


name: ADP + H(+) + O-phospho-L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] => ATP + L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase]


name: 2-aminomuconate 6-semialdehyde + CO2 => 2-amino-3-carboxymuconate 6-semialdehyde + H(+)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Dictyostelium discoideum)


name: ATP + benzoate + H(+) <=> benzoyl-AMP + diphosphate


name: 5-amino-1-(beta-D-ribosyl)imidazole + ATP => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+)


name: hexadecanoyl-CoA + octan-1-ol = CoA + octyl hexadecanoyl


name: RHOQ binds effectors at the plasma membrane (Sus scrofa)


name: PHF8 demethylates histone H4K20me1 (Sus scrofa)


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + [thyroglobulin]-3-iodo-L-tyrosine + H2O2 => [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: MKRN1 polyubiquitinates PTEN (Schizosaccharomyces pombe)


name: ST3GAL5 transfers NeuNAc to ceramides (Sus scrofa)


name: 5-guanidino-2-oxopentanoate + H(+) + NADPH + NH4(+) => H2O + L-arginine + NADP(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 9-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a pyrimidine ribonucleoside + H2O => a pyrimidine nucleobase + D-ribose


name: 16alpha-hydroxydehydroepiandrosterone 3-sulfate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dehydroepiandrosterone 3-sulfate + O2 + reduced [NADPH--hemoprotein reductase]


name: NADP(+) + shikimate => 3-dehydroshikimate + H(+) + NADPH


name: CDP(out) + CDP-L-ribitol(in) => CDP(in) + CDP-L-ribitol(out)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol <=> an N-acylsphing-4-enine + cholesteryl 3-beta-D-glucoside


name: (+)-5-epi-aristolochene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => capsidiol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Defective LCT does not hydrolyze Lac (Homo sapiens)


name: Phosphorylated HSL dimer translocates from the cytosol to the lipid particle (Homo sapiens)


name: GDIs block activation of RHOG (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: p-S363,S380,T573 RS6K translocates to the nucleus (Canis familiaris)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Drosophila melanogaster)


name: (2Z,6E)-farnesyl diphosphate <=> (E)-beta-farnesene + diphosphate


name: ADP-Ribosylation of HNP-1 (Homo sapiens)


name: KLK5 cleaves and activates KLK8 (Homo sapiens)


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Schizosaccharomyces pombe)


name: N(pros)-phospho-L-histidyl-[protein] + N,N'-diacetylchitobiose(out) = diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein]


name: (S)-scoulerine + 2-oxoglutarate + O2 = (S)-3-O-demethylscoulerine + CO2 + formaldehyde + succinate


name: Caspase-mediated cleavage of GAS2 (Xenopus tropicalis)


name: D-ribulose + H(+) + NADH => D-arabinitol + NAD(+)


name: ADIPOQ trimer binds ADIPOR dimers (Bos taurus)


name: 2 L-arginine + 4 O2 + 3 reduced [flavodoxin] => 5 H(+) + 4 H2O + 2 L-citrulline + 2 nitric oxide + 3 oxidized [flavodoxin]


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Canis familiaris)


name: glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho]-glycerol + CoA


name: p-EPHs bind SRC,FYN,YES,LYN (Homo sapiens)


name: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO2


name: transcription regulatory region nucleic acid binding


name: anserine + H(+) + S-adenosyl-L-homocysteine => carnosine + S-adenosyl-L-methionine


name: Phosphorylation of TSC2 by PKB (Homo sapiens)


name: alpha-maltotetraose + beta-maltose => alpha-maltopentaose + beta-D-glucose


name: TP53 binds TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D genes (Homo sapiens)


name: OPLAH hydrolyses OPRO to L-Glu (Caenorhabditis elegans)


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Xenopus tropicalis)


name: cytidine(1404) in 16S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(1404) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[quaternary-amine-specific corrinoid protein] <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[quaternary-amine-specific corrinoid protein] + H(+)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Neuromedin-U receptors bind neuromedins U, S (Mus musculus)


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Rattus norvegicus)


name: Binding of IP3 to IP3 receptor (Mus musculus)


name: 3-oxooctanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxyoctanoyl-[ACP] + NADP(+)


name: 3-hydroxybenzoate + ATP + H(+) + NADPH <=> 3-hydroxybenzaldehyde + AMP + diphosphate + NADP(+)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Bos taurus)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine => 1-tetradecanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: A + an aldehyde + H2O = a carboxylate + AH2 + H(+)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1 (Homo sapiens)


name: pro-RAS proteins are farnesylated (Drosophila melanogaster)


name: 12-hydroxyoctadecanoate + ATP + CoA <=> 12-hydroxyoctadecanoyl-CoA + AMP + diphosphate


name: 3-hydroxybutane-1,2,3-tricarboxylate <=> pyruvate + succinate


name: HMGB1 binds TLR4:LY96 (Rattus norvegicus)


name: cyclo(L-phenylalanyl-L-leucyl) + O2 => cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2


name: N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine <=> H(+) + N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + UDP


name: RIPK1 is cleaved by CASP8 (Gallus gallus)


name: a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-methionine = a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine


name: L-phenylalanine + oxaloacetate => 3-phenylpyruvate + L-aspartate


name: PXLP-K56-SRR dimer deaminates L-Ser (Canis familiaris)


name: (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NAD(+) => (S)-cystathionine ketimine + 2 H(+) + NADH


name: IRAK2 induces TRAF6 oligomerization (Rattus norvegicus)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + H(+)


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] <=> 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]


name: (S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-nandinine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: L-2,4-diaminobutanoate + pyruvate = L-alanine + L-aspartate 4-semialdehyde


name: (R)-adrenaline(in) + 2 H(+)(out) = (R)-adrenaline(out) + 2 H(+)(in)


name: PRICKLE1 is degraded by the proteasome (Danio rerio)


name: RHOG binds effectors at the plasma membrane (Xenopus tropicalis)


name: H2O + NAD(+) + sulfoacetaldehyde <=> 2 H(+) + NADH + sulfoacetate


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Rattus norvegicus)


name: Integrin alpha6beta1, alpha7beta1, alpha1beta1, alpha2beta1 bind laminin-111 (Homo sapiens)


name: cytidine(32) in tRNA(Thr) + S-adenosyl-L-methionine => H(+) + N(3)-methylcytidine(32) in tRNA(Thr) + S-adenosyl-L-homocysteine


name: 3-hydroxypropanoate + NAD(+) <=> 3-oxopropanoate + H(+) + NADH


name: (2E,6E)-farnesyl diphosphate + orsellinate => diphosphate + ilicicolinate B


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Xenopus tropicalis)


name: EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Bos taurus)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Drosophila melanogaster)


name: 26S proteasome degrades Ub-NFE2L2 (Caenorhabditis elegans)


name: ATP + L-rhamnulose = ADP + H(+) + L-rhamnulose 1-phosphate


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Homo sapiens)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Caenorhabditis elegans)


name: PXLP-K754-GLDC dimer decarboxylates Gly (Canis familiaris)


name: 5-methylcytidine(62) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine => cytidine(62) in tRNA(Asp) + S-adenosyl-L-methionine


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Gallus gallus)


name: Interaction of particulate antigens with dendritic cell receptors (Canis familiaris)


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 (Drosophila melanogaster)


name: GLI proteins bind SUFU (Drosophila melanogaster)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Plasmodium falciparum)


name: (11Z,14Z,17Z)-eicosatrienamide + H2O <=> (11Z,14Z,17Z)-eicosatrienoate + NH4(+)


name: FUT3 transfers L-fucose to Gal1,3GlcNAc (Canis familiaris)


name: (S)-4-hydroxymandelonitrile => 4-hydroxybenzaldehyde + hydrogen cyanide


name: 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + CoA + H(+)


name: carbohydrate derivative transmembrane transporter activity


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Caenorhabditis elegans)


name: SFTPB dimer,C translocate from multivesicle body to lamellar body (Canis familiaris)


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Canis familiaris)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + diphosphate <=> 5-amino-4-imidazolecarboxyamide + 5-phospho-alpha-D-ribose 1-diphosphate


name: NADH + O2 + rifamycin SV = H2O + NAD(+) + rifamycin SV para-naphthoquinone carboxamide


name: (S)-malate(in) + 2-oxoglutarate(out) <=> (S)-malate(out) + 2-oxoglutarate(in)


name: intracellularly gated calcium channel activity


name: ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Homo sapiens)


name: IKBKG subunit of IKK complex binds polyubiquinated RIP1 (Mus musculus)


name: L-glutamine + scyllo-inosose = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate


name: ADP + H(+) + O-phospho-L-seryl-[protein] => ATP + L-seryl-[protein]


name: CYP4F8 19-hydroxylates PGH2 (Sus scrofa)


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Bos taurus)


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Bos taurus)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + AH2 + O2 = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + A + 2 H2O


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Homo sapiens)


name: CYB5Rs reduce MetHb to HbA (Homo sapiens)


name: 2 H(+)(in) + H2 + ubiquinone-8 => 2 H(+)(out) + ubiquinol-8


name: RAR:RXR binds SUMO-CRABP2:atRA (Drosophila melanogaster)


name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Gallus gallus)


name: ZIP6 and ZIP14 mediate zinc influx into cells (Mus musculus)


name: Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Homo sapiens)


name: SRF stimulates NPAS4 gene transcription (Homo sapiens)


name: ATP + pyridoxine <=> ADP + H(+) + pyridoxine 5'-phosphate


name: N-formimidoylglycine + NH4(+) => 4-aminoimidazole + H(+) + 2 H2O


name: (9Z,12Z,15Z)-octadecatrienoate + O2 <=> (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: dodecanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4-hydroxy-6-(2-oxotridecyl)pyran-2-one + 3 CO2 + 4 CoA


name: a ganglioside GD3 + H2O <=> a ganglioside GM3 + N-acetylneuraminate


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Homo sapiens)


name: IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Homo sapiens)


name: a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + FMN + 2 H(+) => a 5'-end FAD-phospho-ribonucleoside in mRNA + H2O


name: PGA2 is isomerised to PGC2 (Homo sapiens)


name: ACY3:Zn2+ dimer hydrolyses mercapturic acids (Danio rerio)


name: (E)-coniferyl acetate + NADPH => (E)-isoeugenol + acetate + NADP(+)


name: a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Caenorhabditis elegans)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Gallus gallus)


name: 3beta-hydroxyandrost-5-en-17-one + NAD(+) <=> androst-5-ene-3,17-dione + H(+) + NADH


name: OCT1 transports organic cations out of hepatic cells (Caenorhabditis elegans)


name: mannose transmembrane transporter activity


name: RHOC translocates to the endoplasmic reticulum membrane (Mus musculus)


name: Formation of AT-AC C complex (Caenorhabditis elegans)


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)


name: campesterol + O2 + reduced [NADPH--hemoprotein reductase] => (22S)-22-hydroxycampesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Digestion of branched starch (amylopectin) by extracellular amylase (Canis familiaris)


name: XIAP binds CASP9 (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 9R-hydroperoxy(5Z,7E,11Z,14Z)-eicosatetraenoate


name: CO2 + isopentenyl phosphate + phosphate => (R)-3,5-bisphosphomevalonate + H(+)


name: 3-oxoadipate + NAD(+) <=> H(+) + maleylacetate + NADH


name: Receptor CCR7 binds CCL19 and 21 ligands (Canis familiaris)


name: RUNX1 binds SIN3A,(SIN3B) co-repressor (Sus scrofa)


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Drosophila melanogaster)


name: A1 and A3 receptors bind adenosine (Homo sapiens)


name: GDIs block activation of RHOB (Canis familiaris)


name: FP-1039 acts as a ligand-trap for FGFR2b-binding ligands in endometrial cancer (Homo sapiens)


name: EHMT1:EHMT2 dimethylates TP53 (Bos taurus)


name: STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Homo sapiens)


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Homo sapiens)


name: Ferriheme is transferred from Albumin to Hemopexin (Bos taurus)


name: NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP (Caenorhabditis elegans)


name: D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein] <=> 6-phospho-beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein]


name: PC is converted to PS by PTDSS1 (Mus musculus)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Danio rerio)


name: 1,5-anhydro-D-mannitol + NADP(+) <=> 1,5-anhydro-D-fructose + H(+) + NADPH


name: "Kdo2-lipid A phosphoethanolamine 7''-transferase"


name: CDC42 GEFs activate CDC42 (Dictyostelium discoideum)


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Sus scrofa)


name: Laminins:Nidogens binds collagen type IV networks (Rattus norvegicus)


name: a ganglioside GD3 (d18:1(4E)) + H2O = a ganglioside GM3 (d18:1(4E)) + N-acetylneuraminate


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Rattus norvegicus)


name: a globoside Gb3Cer + H2O <=> a fatty acid + a lysoGb3


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Xenopus tropicalis)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Mus musculus)


name: UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Mus musculus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Gallus gallus)


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Rattus norvegicus)


name: PDSS1,2 ligates FPP to IPPP (Homo sapiens)


name: ATP + D-mannose = ADP + D-mannose 6-phosphate + H(+)


name: Calmodulin activates Cam-PDE 1 (Gallus gallus)


name: SUMOylation of NFKB2 with SUMO1 (Mus musculus)


name: GDP-beta-L-colitose + NAD(+) => GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + H(+) + NADH


name: (20S)-ginsenoside F2 + H(+) + UDP => (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3-O-beta-D-glucoside <=> an anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] + CoA + H(+)


name: MRN activates ATM (Drosophila melanogaster)


name: Cytosolic JET binds to CRY, facilitating its ubiquitination (Drosophila melanogaster)


name: ACSS3 ligates CoA to CH3COO- (Homo sapiens)


name: SEC24A,B:SEC23A bind SEC22B (Homo sapiens)


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Dictyostelium discoideum)


name: Activation of RAS by p-KIT bound SOS1 (Canis familiaris)


name: CMBL hydrolyses OM to OLMS (Xenopus tropicalis)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Drosophila melanogaster)


name: pseudouridine(31) in tRNA => uridine(31) in tRNA


name: CHOL translocates from cytosol to mitochondrial intermembrane space (Rattus norvegicus)


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Xenopus tropicalis)


name: AOX1 oxidises PXL to PDXate (Homo sapiens)


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Canis familiaris)


name: formononetin + O2 + reduced [NADPH--hemoprotein reductase] => 2'-hydroxyformononetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O <=> a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+)


name: 2-deoxy-D-ribose 5-phosphate => acetaldehyde + D-glyceraldehyde 3-phosphate


name: Activation of HCN channels (Canis familiaris)


name: (2S)-2-nitrosobutanedioate + H(+) + NADPH + O2 = 2-nitrobutanedioate + H2O + NADP(+)


name: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesol + diphosphate


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Xenopus tropicalis)


name: macrocin + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + tylosin


name: EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Homo sapiens)


name: Formation of dsRNA structure by looping  (Homo sapiens)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Drosophila melanogaster)


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)


name: VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Schizosaccharomyces pombe)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Mus musculus)


name: cytosine + D-ribose 5-phosphate => CMP + H2O


name: H(+)(out) + L-leucyl-L-proline(out) => H(+)(in) + L-leucyl-L-proline(in)


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Homo sapiens)


name: p100:RELB binds active NIK:p-IKKA dimer (Rattus norvegicus)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Drosophila melanogaster)


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Danio rerio)


name: ME1 tetramer decarboxylates OA to PYR (Rattus norvegicus)


name: H(+) + NADH + O2 + theophylline => 3-methylxanthine + formaldehyde + H2O + NAD(+)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Mus musculus)


name: kaempferol 3-glucoside 7-O-rhamnosyltransferase activity


name: Cytosolic glycoconjugates translocate to the lysosome (Homo sapiens)


name: 2 H(+) + metoxuron + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 3-(3-chloro-4-methoxylphenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: GMPS dimer transforms 6TXMP to 6TGMP (Caenorhabditis elegans)


name: CTP(in) + UMP(out) => CTP(out) + UMP(in)


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Rattus norvegicus)


name: Binding of Syk tyrosine kinase (Homo sapiens)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Bos taurus)


name: Activated type I receptor phosphorylates SMAD2/3 directly (Homo sapiens)


name: p-6Y-VEGFR2 binds SHB  (Rattus norvegicus)


name: 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate => H2O + xanthurenate


name: Hemoglobin:Haptoglobin:CD163 is endocytosed (Sus scrofa)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Drosophila melanogaster)


name: H(+) + hydrogencarbonate + NADH + propanoyl-CoA => (S)-2-methyl-3-oxopropanoate + CoA + H2O + NAD(+)


name: (9Z)-octadecenoyl-CoA + 1-O-hexadecylglycerol => 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Dictyostelium discoideum)


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Drosophila melanogaster)


name: H(+) + NADH + O2 + propene <=> 1,2-epoxypropane + H2O + NAD(+)


name: (2E,6E)-farnesyl diphosphate + H(+) + NADPH + O2 => (2E,6E)-omega-hydroxy-farnesyl diphosphate + H2O + NADP(+)


name: SPHK2 binds SPHK2 inhibitors (Mus musculus)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Danio rerio)


name: CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Dictyostelium discoideum)


name: NEIL3 cleaves spiroiminodihydantoin (Mus musculus)


name: 4-hydroxybutanoate + NADP(+) <=> H(+) + NADPH + succinate semialdehyde


name: 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O <=> (9Z)-octadecenoate + 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H(+)


name: D-arabinonate + H(+) => D-arabinono-1,4-lactone + H2O


name: Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes (Rattus norvegicus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Drosophila melanogaster)


name: p-S207 KARS displaces HINT1 (Caenorhabditis elegans)


name: ARSA removes sulfate from PSAP(195-273):Sulfatide (Homo sapiens)


name: RNA polymerase III general transcription initiation factor activity


name: phosphate + sucrose 6(F)-phosphate => alpha-D-glucose 1-phosphate + beta-D-fructose 6-phosphate


name: Epsin family proteins bind ubiquitinated cargo (Sus scrofa)


name: Recruitment of Grb2 to pFAK:NCAM1 (Caenorhabditis elegans)


name: PDGF-AA clevage by Furin (Caenorhabditis elegans)


name: H2O + N-eicosanoylglycinate => eicosanoate + glycine


name: NADP(+) + octadecanoyl-CoA => (2E)-octadecenoyl-CoA + H(+) + NADPH


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Homo sapiens)


name: 2 L-glutamate + 2 oxidized [2Fe-2S]-[ferredoxin] => 2-oxoglutarate + 2 H(+) + L-glutamine + 2 reduced [2Fe-2S]-[ferredoxin]


name: alpha-D-ribose 1,5-bisphosphate + cytosine => CMP + phosphate


name: estrone 3-sulfate(out) + L-glutamate(in) => estrone 3-sulfate(in) + L-glutamate(out)


name: gibberellin A17,oxoglutarate:oxygen oxidoreductase activity


name: a medium-chain primary fatty alcohol + NADP(+) = a medium-chain fatty aldehyde + H(+) + NADPH


name: H(+) + N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: botD LC cleaves target cell VAMP2 (Homo sapiens)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Caenorhabditis elegans)


name: CysS248-MPST:TXN2 dissociates (Caenorhabditis elegans)


name: p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol (Rattus norvegicus)


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Mus musculus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 => 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O


name: 15-cis-phytoene + 4 A <=> 4 AH2 + all-trans-lycopene


name: Cysteine is degraded to serine and H2S (Sus scrofa)


name: aphidicolan-16beta-ol + diphosphate => 9alpha-copalyl diphosphate + H2O


name: a very long-chain fatty acyl-CoA + H2O => a very long-chain fatty acid + CoA + H(+)


name: (4S)-perillyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase]


name: Myosin phosphatase dephosphorylates PLK1 (Sus scrofa)


name: MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)


name: COPII coat binds TRAPPCII and RAB1:GDP (Schizosaccharomyces pombe)


name: (2E,6E)-farnesyl diphosphate = (-)-germacrene D + diphosphate


name: Assembly of the pre-incision complex in TC-NER (Homo sapiens)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: SALMs1-3 bind each other in cis interactions (Xenopus tropicalis)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Homo sapiens)


name: 2 H(+) + O2 + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H2O


name: 9alpha-copalyl diphosphate + H2O => diphosphate + syn-copalol


name: ent-cassa-12,15-dien-2beta,3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1-O-hexadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a 1-O-(1Z-hexadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: O2 + tetradecanoate <=> (2R)-2-hydroperoxytetradecanoate


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Canis familiaris)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Xenopus tropicalis)


name: ATP2B4 binds to NOS1, inhibiting it (Canis familiaris)


name: NEIL3 recognizes and binds to spiroiminodihydantoin in telomeric DNA (Homo sapiens)


name: GABA loaded synaptic vesicle Docking and Priming (Mus musculus)


name: D-xylobiose + O2 <=> D-xylobiono-1,5-lactone + H2O2


name: H2O + S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] => H(+) + L-cysteinyl-[protein] + lactate


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA


name: LIG3 ligates remaining SSBs in MMEJ (Homo sapiens)


name: glycoursodeoxycholate(out) + 2 Na(+)(out) <=> glycoursodeoxycholate(in) + 2 Na(+)(in)


name: alpha-isomaltosyl-(1->3)-isomaltose + H2O <=> 2 isomaltose


name: MDM2 forms homo- or heterodimers (Gallus gallus)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Dictyostelium discoideum)


name: 4-acetamidobutanoate + H2O => 4-aminobutanoate + acetate


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Drosophila melanogaster)


name: WLS is endocytosed to the early endosome (Gallus gallus)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Saccharomyces cerevisiae)


name: USP20, USP33 deubiquitinate ADRB2 (Drosophila melanogaster)


name: Parkin binds Ub:UBE2N:UBE2V1 (Danio rerio)


name: ST6GALNAC2 transfers sialic acid to Core 1 mucins (Sus scrofa)


name: 8-oxo-dGDP + H2O = 8-oxo-dGMP + H(+) + phosphate


name: ATP + beta-alanine + dopamine <=> AMP + beta-alanyl-dopamine + diphosphate + H(+)


name: Exocytosis of azurophil granule lumen proteins (Plasmodium falciparum)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Rattus norvegicus)


name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter (Homo sapiens)


name: hydroquinone + NADP(+) => 1,4-benzoquinone + H(+) + NADPH


name: Dopamine is oxidised to noradrenaline (Bos taurus)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO1 (Caenorhabditis elegans)


name: α2-agonists bind ADRA2A,B,C (Mus musculus)


name: Caspase mediated cleavage of alpha-II-Fodrin (Rattus norvegicus)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Sus scrofa)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Schizosaccharomyces pombe)


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: H2O + N-(octadecanoyl)-sphinganine <=> octadecanoate + sphinganine


name: ATP(in) + UDP(out) <=> ATP(out) + UDP(in)


name: Retromer recycles WLS to the Golgi (Canis familiaris)


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Bos taurus)


name: NLRP3 activation by small molecules (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate => (-)-alpha-gurjunene + diphosphate


name: RLBP1:11cRAL dissociates (Canis familiaris)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Caenorhabditis elegans)


name: AFG3L2 binds mitochondrial matrix proteins (Saccharomyces cerevisiae)


name: Phosphorylation of LAT by p-SYK (Sus scrofa)


name: M dimer gets exported from nucleus (Homo sapiens)


name: H(+) + phosphoenolpyruvate => 3-phosphonopyruvate


name: NMT1/2 transfer MYS to GNAT1 (Mus musculus)


name: H2O + N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine = D-glucose + N-acyl-15-methylhexadecasphing-4-enine


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Dictyostelium discoideum)


name: H2O + sphinga-4E,14Z-dienine-1-phosphate => phosphate + sphinga-4E,14Z-dienine


name: IL27 translocates from the cytosol to the extracellular space (Homo sapiens)


name: (S)-malate + NAD(+) => CO2 + NADH + pyruvate


name: H2O + streptothricin F => streptothricin F acid


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Caenorhabditis elegans)


name: 2 1-O-galloyl-beta-D-glucose <=> 1,6-bis-O-galloyl-beta-D-glucose + D-glucose


name: GPER:Heterotrimeric G-protein Gs binds ESTG (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (-)-spiroviolene + diphosphate


name: NAD(+) <=> 3'cADPR + H(+) + nicotinamide


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Xenopus tropicalis)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Canis familiaris)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Dictyostelium discoideum)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: 3-(aminomethyl)indole + S-adenosyl-L-methionine = (1H-indol-3-yl)-N-methylmethanamine + H(+) + S-adenosyl-L-homocysteine


name: 2-methylpropanoyl phosphate + ADP => 2-methylpropanoate + ATP


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Caenorhabditis elegans)


name: Relocalization of nuclearly localized Cyclin D1 to the cytoplasm (Sus scrofa)


name: RHOA:GTP binds ROCK, activating it (Xenopus tropicalis)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Rattus norvegicus)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Danio rerio)


name: Recruitment of PLCgamma to membrane (Sus scrofa)


name: glutaryl-CoA + H(+) + malonyl-[ACP] => 3-oxo-6-carboxyhexanoyl-[ACP] + CO2 + CoA


name: 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H(+) => deacetylpyripyropene E


name: Opioid receptors bind opioid peptides (Mus musculus)


name: Production of AA by iPLA2 upon FCGR activation (Mus musculus)


name: RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)


name: PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Mus musculus)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN2D (GRIN2D) (Homo sapiens)


name: H(+)(in) + thiamine(out) => H(+)(out) + thiamine(in)


name: TRAF6 is auto-ubiquitinated (Mus musculus)


name: 2 H(+) + NADH + phosphonoacetate => H2O + NAD(+) + phosphonoacetaldehyde


name: D-gluconate(in) + H(+)(in) <=> D-gluconate(out) + H(+)(out)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Sus scrofa)


name: VTN binds Plasminogen activator inhibitor- 1 (Sus scrofa)


name: 4-aminobenzoate + all-trans-hexaprenyl diphosphate => 4-amino-3-all-trans-hexaprenylbenzoate + diphosphate


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Bos taurus)


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Bos taurus)


name: CYP19A1 hydroxylates ANDST to E1 (Homo sapiens)


name: PTN and MDK bind to PTPRZ (Canis familiaris)


name: H2O + N-acetyltyramine <=> acetate + tyramine


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Drosophila melanogaster)


name: Autophagosome maturation (Dictyostelium discoideum)


name: L-arginine(in) + L-cystine(out) => L-arginine(out) + L-cystine(in)


name: (3S)-hydroxyhexadecanedioyl-CoA + NAD(+) => 3-oxohexadecanedioyl-CoA + H(+) + NADH


name: (3R)-1,4-thiomorpholine-3-carboxylate + NAD(+) = 3,4-dehydrothiomorpholine-3-carboxylate + 2 H(+) + NADH


name: ERCC1:XPF cleaves flaps generated by SSA (Rattus norvegicus)


name: hydroxyurea + O-acetyl-L-serine = acetate + H(+) + O-ureido-L-serine


name: (2E)-2-butenoate + ATP + H(+) => (2E)-but-2-enoyl-AMP + diphosphate


name: 2xPPCS ligates PPanK with Cys (Bos taurus)


name: 6,7-dihydropteridine + H(+) + NADH => 5,6,7,8-tetrahydropteridine + NAD(+)


name: NAD(+) + taurochenodeoxycholate = 7-oxotaurolithocholate + H(+) + NADH


name: ATP + holo-[peptidyl-carrier protein] + L-alanine = AMP + diphosphate + L-alanyl-[peptidyl-carrier protein]


name: Interaction of integrin alpha8beta1 with Tenascin-C (Bos taurus)


name: Collagen type XII degradation by MMP12 (Gallus gallus)


name: O2 + piceatannol => 3,4-dihydroxybenzaldehyde + 3,5-dihydroxybenzaldehyde


name: Separation of elongating transcript from template (Gallus gallus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine => 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine


name: serine-type D-Ala-D-Ala carboxypeptidase activity


name: cholesterol + H(+) + NADH + O2 <=> 7-dehydrocholesterol + 2 H2O + NAD(+)


name: 2 H(+) + monuron + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3-(4-chlorophenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ATP + H2O + tetracosanoate(in) = ADP + H(+) + phosphate + tetracosanoate(out)


name: H2O + N-acetyl-D-mannosamine + phosphoenolpyruvate = N-acetylneuraminate + phosphate


name: p-STAT1 dissociates from IL6ST:IL6ST (Canis familiaris)


name: devancoaminyl-vancomycin + dTDP-beta-L-4-epi-vancosamine => chloroorienticin B + dTDP + H(+)


name: indole-3-pyruvate imine dimer <=> CO2 + NH4(+) + protodeoxyviolaceinate


name: 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA (Dictyostelium discoideum)


name: GTP-bound RAC contributes to JNK activation (Canis familiaris)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Saccharomyces cerevisiae)


name: ethylenediaminediacetate + 2 FMN + 2 glyoxylate + 3 H(+) + 2 H2O => EDTA + 2 FMNH2 + 2 O2


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Sus scrofa)


name: NACT co-transports trivalent citrate and a sodium ion (Bos taurus)


name: CoA + N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] => acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein]


name: O2 + sym-homospermidine <=> H2O2 + N-(4-aminobutylpyrrolinium) ion + NH4(+)


name: 1-O-alkyl-2-acyl-sn-glycerol + CDP-ethanolamine => 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: Furin cleaves pro-protein S to protein S (Canis familiaris)


name: Activated FGFR2 binds FRS2 (Canis familiaris)


name: Inactive G alpha (i) reassociates with G beta:gamma (Gallus gallus)


name: (E)-ferulate + ATP + H(+) => (E)-feruloyl-AMP + diphosphate


name: SRD5A2 binds SRD5A2 inhibitors (Canis familiaris)


name: HSPG2 (perlecan) degradation by MMP14, MMP15 (Homo sapiens)


name: Activated protein C is released from PROCR (Sus scrofa)


name: IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Canis familiaris)


name: gamma-secretase cleaves EPHB2 (Danio rerio)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: 5,6-dihydrouridine(20b) in tRNA + NAD(+) <=> H(+) + NADH + uridine(20b) in tRNA


name: prephenate dehydrogenase (NADP+) activity


name: delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity


name: 14-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate


name: 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + H(+) + NADPH + O2 => H2O + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate + NADP(+)


name: 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine => a 1,2-diacyl-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: SLP-76 stimulates PLC gamma 2 (Sus scrofa)


name: DLD dimer dehydrogenates dihydrolipoyl (Caenorhabditis elegans)


name: 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP <=> 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Canis familiaris)


name: 8-methylmenaquinone-6 + succinate = 8-methylmenaquinol-6 + fumarate


name: glutaryl-CoA + H2O => CoA + glutarate + H(+)


name: (1R,5R)-sabinene + diphosphate => (2E)-geranyl diphosphate


name: WWTR1 (TAZ), TBX5, and PCAF form a complex (Canis familiaris)


name: AH2 + Latia luciferin + 2 O2 = A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin


name: Tetramerization of procollagen VI (Caenorhabditis elegans)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NADP(+) <=> 3-(4-hydroxyphenyl)pyruvate + H(+) + NADPH


name: IRS1 recruits GRB2 to active LTK (Homo sapiens)


name: Aquaporin-9 passively transports glycerol into cell (Saccharomyces cerevisiae)


name: 24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: [(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-beta-D-glucosyl](n+1) + H(+) + UDP


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Canis familiaris)


name: alfacalcidol + O2 + reduced [NADPH--hemoprotein reductase] <=> calcitriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: auxin influx transmembrane transporter activity


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)


name: Interaction of APS and p-KIT (Rattus norvegicus)


name: Formation of pre-mRNPs (Saccharomyces cerevisiae)


name: Inactivation of Wee1 kinase (Gallus gallus)


name: ATP + holo-[peptidyl-carrier protein] + L-serine <=> AMP + diphosphate + L-seryl-[peptidyl-carrier protein]


name: E2F6 binds the PRC1 complex (Canis familiaris)


name: trans-Golgi Network Coat Assembly (Homo sapiens)


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Mus musculus)


name: L-tyrosine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: CD38 hydrolyses NAD+ to NAM and ADP-ribose (Canis familiaris)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Bos taurus)


name: 2 AH2 + all-trans-4,4'-diaponeurosporene + 2 O2 = 4,4'-diaponeurosporenal + 2 A + 3 H2O


name: L-threonyl-[protein] + octanoyl-CoA = CoA + O-octanoyl-L-threonyl-[protein]


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Caenorhabditis elegans)


name: SESN1,2,3 bind AMPK (Caenorhabditis elegans)


name: L-glutaminyl-[protein] + L-lysyl-[protein] => [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4(+)


name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] (Drosophila melanogaster)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Mus musculus)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z,12Z)-octadecadienoate + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+)


name: protoaphin aglucone <=> H2O + xanthoaphin


name: O-atom dealkylation of dextromethorphan (Drosophila melanogaster)


name: PINK1 phosphorylates Ub on MOM proteins (Danio rerio)


name: Raf dimer inhibitors bind RAF heterodimers (Mus musculus)


name: NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) (Homo sapiens)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Dictyostelium discoideum)


name: ISGylation of DDX58 (Caenorhabditis elegans)


name: IL6R binds IL6R inhibitors (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)


name: Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)


name: Cleavage of Procaspase-3 by the apoptosome (Gallus gallus)


name: L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Schizosaccharomyces pombe)


name: B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac (Danio rerio)


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Mus musculus)


name: 16,17-epoxy-(7Z,10Z,13Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA <=> (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H2O


name: ATP + CoA + isophthalate = AMP + diphosphate + isophthalyl-CoA


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)


name: ALOX12 oxidises LTA4 to LXA4/B4 (Canis familiaris)


name: TBC1D3 associates with RAB5 (Drosophila melanogaster)


name: a medium-chain fatty acyl-CoA + acetyl-CoA <=> a medium-chain 3-oxoacyl-CoA + CoA


name: Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)


name: PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Homo sapiens)


name: MME:Zn2+ binds sacubitrilat (Gallus gallus)


name: alpha-tubulin:GTP + Cofactor B -> alpha-tubulin:GTP: Cofactor B (Homo sapiens)


name: 1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity


name: candesartan + UDP-alpha-D-glucuronate = candesartan O-beta-D-glucuronoside + UDP


name: STAB1:ligand is endocytosed (Gallus gallus)


name: N-hydroxy-L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase]


name: D-octopine + H2O + NAD(+) = H(+) + L-arginine + NADH + pyruvate


name: (3R)-citramalate <=> 2-methylmaleate + H2O


name: [1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + H(+) + UDP


name: DAG and Ca+2 bind to PKC and tether it to membrane (Rattus norvegicus)


name: (6E)-8-hydroxygeranial + NADP(+) = (6E)-8-oxogeranial + H(+) + NADPH


name: succinate + FAD <=> fumarate + FADH2 (Gallus gallus)


name: Binding of CBL to EGFR (Canis familiaris)


name: a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione => a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O


name: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Canis familiaris)


name: RBBP7 binds histone H3 (Schizosaccharomyces pombe)


name: ATP + L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) = ADP + H(+) + L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Canis familiaris)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Canis familiaris)


name: 3-dehydro-L-gulonate + ATP => 3-dehydro-L-gulonate 6-phosphate + ADP + H(+)


name: H2O + N-acetyl-L-phenylalanine => acetate + L-phenylalanine


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + H(+)(in) <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + H(+)(out)


name: Exocytosis of ficolin-rich granule membrane proteins (Schizosaccharomyces pombe)


name: ATP + cob(II)yrinate c monoamide + H2O + L-glutamine = ADP + cob(II)yrinate a,c diamide + H(+) + L-glutamate + phosphate


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Bos taurus)


name: (S)-allantoin(out) + H(+)(out) => (S)-allantoin(in) + H(+)(in)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + H(+) + hexadecanoate


name: 2'-deoxycytidine + ATP => ADP + dCMP + H(+)


name: 3-chloro-D-alanine + H2O => chloride + H(+) + NH4(+) + pyruvate