name: [phosphate](n) + ADP <=> [phosphate](n+1) + AMP


name: α1-agonists bind ADRA1A,B,D (Bos taurus)


name: H(+) + NADH + uridine(16) in tRNA => 5,6-dihydrouridine(16) in tRNA + NAD(+)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-(2S,3R,9R)-pristinol + diphosphate


name: Adenylate cyclase converts ATP into cyclic AMP (Caenorhabditis elegans)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Canis familiaris)


name: (R)-glycerate + AH2 + H(+) => A + D-glyceraldehyde + H2O


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Homo sapiens)


name: (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-glycerol + H(+) => 1,2-di-(9Z-octadecenoyl)-glycerol + H2O


name: SENP1,2,5 proteolytically process SUMO2 (Plasmodium falciparum)


name: Formation of TRAP coactivator complex (Gallus gallus)


name: (1S)-1,23-dihydroxy-24,25,26,27-tetranorcalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (1S)-1-hydroxy-23-oxo-24,25,26,27-tetranorcalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Bos taurus)


name: Formation of NR-MED1 Coactivator Complex (Homo sapiens)


name: SLC7A8-mediated uptake of neutral amino acids (Rattus norvegicus)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Drosophila melanogaster)


name: Exocytosis of ficolin-rich granule membrane proteins (Dictyostelium discoideum)


name: USP13 deubiquitinates BECN1,USP10 (Mus musculus)


name: 4-phosphooxy-L-aspartyl-tRNA(Asn) + NH4(+) = H(+) + L-asparaginyl-tRNA(Asn) + phosphate


name: type 2 proteinase activated receptor binding


name: Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose (Mycobacterium tuberculosis)


name: Replication transcription complex binds SARS-CoV-1 genomic RNA (Homo sapiens)


name: H(+) + hexadecanoate + sn-glycerol 3-phosphocholine => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: Association of procollagen type V (Xenopus tropicalis)


name: PEX19 binds class I peroxisomal membrane proteins (Canis familiaris)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Drosophila melanogaster)


name: guaethol + O2 + reduced [NADH--hemoprotein reductase] = acetaldehyde + catechol + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: H2O + N-(9Z-octadecenoyl)-taurine = (9Z)-octadecenoate + taurine


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Mus musculus)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Saccharomyces cerevisiae)


name: (15Z)-tetracosenamide + H2O => (15Z)-tetracosenoate + NH4(+)


name: Resynthesis of excised residue by POLB (Mus musculus)


name: (R)-(3-(acetylhydroxyamino)-2-hydroxypropyl)phosphonate + CO2 + succinate => 2-oxoglutarate + 3-(N-acetyl-N-hydroxy)aminopropylphosphonate + O2


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Xenopus tropicalis)


name: 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + H2O + O2 <=> a 2'-deoxycytidine in single-stranded DNA + CO2 + glyoxal + succinate


name: GNLY is transferred to the phagosome (Bos taurus)


name: Translocation of tBID to mitochondria (Danio rerio)


name: (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Rattus norvegicus)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Rattus norvegicus)


name: 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+)


name: 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP => 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Rattus norvegicus)


name: [pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate


name: "([Pyruvate, water dikinase] phosphate) phosphotransferase"


name: SEMA7A binds to PLXNC1 (Drosophila melanogaster)


name: PIAS2-2 SUMOylates THRA with SUMO3 (Bos taurus)


name: Keratin type I binds keratin type II (Rattus norvegicus)


name: Mitochondrial recruitment of Drp1 (Saccharomyces cerevisiae)


name: p-6Y-VEGFR2 binds PLCG1 (Canis familiaris)


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Dictyostelium discoideum)


name: Cleavage of uracil by TDG glycosylase (Gallus gallus)


name: FUNDC1 is phosphorylated by CK2 (Dictyostelium discoideum)


name: ATP6AP1 binds V-ATPase (Drosophila melanogaster)


name: alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ (Sus scrofa)


name: 3-oxodecanedioyl-CoA + CoA => acetyl-CoA + octanedioyl-CoA


name: [thyroglobulin]-L-tyrosine + H(+) + H2O2 + iodide = [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH <=> isodeoxycholate + NADP(+)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Canis familiaris)


name: Oxytocin receptor bind oxytocin (Rattus norvegicus)


name: Beta-catenin translocates to the nucleus (Xenopus tropicalis)


name: HTR3A antagonists bind HTR3A pentamer (Mus musculus)


name: SAICAR => AICAR + Fumarate (Rattus norvegicus)


name: 5-methyl-CMP + diphosphate + H(+) => 5-methyl-CTP + H2O


name: H2O2 + tetradecanoate <=> (2S)-hydroxytetradecanoate + H2O


name: GBF1 recruits ARF:GDP to the ERGIC (Saccharomyces cerevisiae)


name: TRAF1 is cleaved by caspases (Homo sapiens)


name: 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> cholesta-5,7-dien-3beta,24S-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AMP(out) + UDP-alpha-D-galactose(in) <=> AMP(in) + UDP-alpha-D-galactose(out)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Sus scrofa)


name: Phosphorylation of Neurofascin (Homo sapiens)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Dictyostelium discoideum)


name: deoxyhumulone + dimethylallyl diphosphate = diphosphate + H(+) + lupulone


name: 5-methyluridine(54) in tRNA + [TtuB sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + ATP + H2O => 5-methyl-2-thiouridine(54) in tRNA + [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + AMP + diphosphate + 2 H(+)


name: glandicoline B + S-adenosyl-L-methionine = H(+) + meleagrin + S-adenosyl-L-homocysteine


name: (3R)-hydroxydocosanoyl-CoA + NAD(+) => 3-oxodocosanoyl-CoA + H(+) + NADH


name: Degradation of multiubiquitinated Cyclin B (Canis familiaris)


name: STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction (Homo sapiens)


name: an aromatic primary alcohol + O2 => an aromatic aldehyde + H2O2


name: holo-[citrate lyase ACP] + S-acetylphosphopantotheine <=> (R)-4'-phosphopantetheine + acetyl-[citrate lyase ACP]


name: a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GD1b (d18:1(4E)) + H(+) + UDP


name: ORC6 is phosphorylated on T195 (Gallus gallus)


name: PIPOX oxidises PPCA to P6C (Canis familiaris)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Danio rerio)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Plasmodium falciparum)


name: POLZ extends translesion synthesis (Bos taurus)


name: 2-O-sulfo-alpha,alpha-trehalose + octadecanoyl-CoA <=> 2-O-sulfo-2'-O-octadecanoyl-alpha,alpha-trehalose + CoA


name: N-hydroxylation of 4-aminobiphenyl (Danio rerio)


name: benzoyl-CoA + H(+) + NADPH + O2 <=> 3-hydroxybenzoyl-CoA + H2O + NADP(+)


name: PA is converted to CDP-DAG by CDS2 (Schizosaccharomyces pombe)


name: (-)-dehydrodiconiferyl alcohol + H(+) + NADPH => (S)-isodihydrodehydrodiconiferyl alcohol + NADP(+)


name: factor VII -> factor VIIa (Mus musculus)


name: ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine => ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Bos taurus)


name: N-WASP binds ARP2/3 and G-actin (Caenorhabditis elegans)


name: Translocation of peptide bound MHC class I complex to cell surface (Rattus norvegicus)


name: GMP + methylglyoxal => N(2)-(1-hydroxy-2-oxopropyl)-GMP


name: (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + O2 => (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O2


name: ARFRP1 recruits ARL1 to the TGN (Caenorhabditis elegans)


name: ATP + L-phenylalanine + tRNA(Phe) <=> AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)


name: PKC phosphorylates GRK2 (Drosophila melanogaster)


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Mus musculus)


name: S-adenosyl-L-methionine + salicylate => methyl salicylate + S-adenosyl-L-homocysteine


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)


name: a carboxylate + D-aspartate => an N-acyl-D-aspartate + H2O


name: F2R:ARRB1 binds MAPKs, SRC-1 (Mus musculus)


name: a quaternary ammonium(in) + ADP + H(+) + phosphate => a quaternary ammonium(out) + ATP + H2O


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-sn-glycero-3-phosphocholine = 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: apo-[aequorin]--coelenterazine => apo-[aequorin] + coelenterazine


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Caenorhabditis elegans)


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Plasmodium falciparum)


name: 2-phenylacetamide + CO2 + H2O => L-phenylalanine + O2


name: Tyrosinase oxidises tyrosine to dopaquinone (Bos taurus)


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Drosophila melanogaster)


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Homo sapiens)


name: a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose <=> a ganglioside GM1 (d18:1(4E)) + H(+) + UDP


name: N-myristoylation of GAG polyprotein by NMT2 (Homo sapiens)


name: p-S92,203-BRF1 binds 14-3-3 (Drosophila melanogaster)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose => alpha-D-Gal-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: neutral L-amino acid transmembrane transporter activity


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Bos taurus)


name: 2-oxoglutarate + L-proline + O2 => cis-3-hydroxy-L-proline + CO2 + succinate


name: CO2 + H2O + kainate + succinate => 2-oxoglutarate + O2 + prekainate


name: alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose = beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: GLI proteins bind PTCH1 gene (Homo sapiens)


name: H2O + N-benzylformamide = benzylamine + formate


name: Phosphorylation of PLC-gamma1 (Homo sapiens)


name: NTPDase3 hydrolyzes nucleoside triphosphates (Canis familiaris)


name: (6Z,9Z,12Z)-octadecatrienoate + H2O => (10S)-hydroxy-(6Z,12Z)-octadecadienoate


name: (3R)-hydroxytetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O


name: (Z)-glucotropeolin + H2O => (Z)-phenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: p-PKR dimer phosphorylates PPP2R5A (Homo sapiens)


name: Bile salts are translocated from the peroxisomal matrix to the cytosol (Homo sapiens)


name: CCDC59:TTF1 binds SFTPB gene (Homo sapiens)


name: SDK1 homophillic interaction (Sus scrofa)


name: propanoyl-CoA + succinate <=> propanoate + succinyl-CoA


name: hexanal + hydrogen cyanide => (2S)-2-hydroxyheptanenitrile


name: ARTN binds RET:GFRA1,GFRA3 (Homo sapiens)


name: Rsu-1 interacts with Pinch1 (Caenorhabditis elegans)


name: LMAN family proteins bind glycosylated cargo (Canis familiaris)


name: CS acetylates OA to citrate (Mus musculus)


name: 4-[(2-hydroxyethoxy)carbonyl]benzoate + H2O = ethylene glycol + H(+) + terephthalate


name: p-PKR dimer phosphorylates MKK6 (Caenorhabditis elegans)


name: NEU4 hydrolyses Neu5Ac from glycoconjugates (Bos taurus)


name: PHF8 demethylates MeK21-histone H4 (Rattus norvegicus)


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Schizosaccharomyces pombe)


name: (3R)-hydroxy-beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial => (3R)-3-hydroxy-10'-apo-beta-carotenal + O2


name: 1-acyl LPI is acylated to PI by MBOAT7 (Sus scrofa)


name: ITCH polyubiquitinates MLKL at K50 (Bos taurus)


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Xenopus tropicalis)


name: (2E)-geranyl diphosphate + isopentenyl diphosphate = (2Z,6E)-farnesyl diphosphate + diphosphate


name: USF1 is phosphorylated by p-MAPK14 (Homo sapiens)


name: RAC1:GTP binds NOX3 complex (Mus musculus)


name: RRAGC,D exchanges GTP for GDP (Danio rerio)


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: L-phenylalanine <=> (E)-cinnamate + NH4(+)


name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 (Sus scrofa)


name: sBAFF trimer binds BAFFR (Canis familiaris)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Homo sapiens)


name: NNMT transfers CH3 from AdoMet to PY (Canis familiaris)


name: Multiubiquitination of APC/C-associated Cdh1 (Homo sapiens)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Dictyostelium discoideum)


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Sus scrofa)


name: a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[alpha-D-galactopyranosyl-(1->2)-alpha-D-glucopyranosyl]-sn-glycerol + H(+) + UDP


name: (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + NADPH = (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + NADP(+)


name: Recruitment of Karyopherin Beta to form a Trimeric Complex (Homo sapiens)


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Rattus norvegicus)


name: 4-hydroxybutanoate + ATP + CoA <=> 4-hydroxybutanoyl-CoA + ADP + phosphate


name: SULTs transfer (SO4)2- group to PREG (Canis familiaris)


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine <=> 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: Glucosylation of collagen propeptide hydroxylysines (Drosophila melanogaster)


name: AKT phosphorylates caspase-9 (Mus musculus)


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + H2O => (9Z)-hexadecenoate + 1,3-di-(9Z)-hexadecenoylglycerol + H(+)


name: ORC1 binds to DNA at origin of replication sites (Homo sapiens)


name: SLCO4C1 mediates the transport of digoxin (Caenorhabditis elegans)


name: CYP21A2 21-hydroxylates PROG (Dictyostelium discoideum)


name: 1-O-hexadecylglycerone 3-phosphate + H(+) + octadecanoate => 1-octadecanoylglycerone 3-phosphate + hexadecan-1-ol


name: PIP2 hydrolysis (Drosophila melanogaster)


name: ADP + H(+) + thiamine diphosphate = adenosine thiamine triphosphate + phosphate


name: (S)-alpha-hydroxyglutarate-gamma-lactone + H2O = 2-hydroxyglutarate + H(+)


name: MECP2 binds GPRIN1 gene promoter (Homo sapiens)


name: a D-hexose + ATP => a D-hexose 6-phosphate + ADP + H(+)


name: Coumarin is 7-hydroxylated by CYP2A13 (Bos taurus)


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Drosophila melanogaster)


name: a globoside Gb3Cer (d18:1(4E)) + H(+) + UDP => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose


name: GBF1 stimulates ARF nucleotide exchange (Mus musculus)


name: Association of procollagen type X (Bos taurus)


name: myo-inositol + S-adenosyl-L-methionine = 1D-3-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: CDK4 inhibitors bind CDK4 (Mus musculus)


name: PDE6 hydrolyses cGMP to GMP (Rattus norvegicus)


name: COMT binds COMT Inhibitors (Schizosaccharomyces pombe)


name: A + peniprequinolone => AH2 + yaequinolone E


name: BOD1L1 binds SET1A complex (Canis familiaris)


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Sus scrofa)


name: a sterol ester + H2O => a fatty acid + a sterol + H(+)


name: cis-1,2-dithiane-4,5-diol + 2 H(+) + hydrogen sulfide + sulfite => dithioerythritol + thiosulfate


name: ATP + CoA + tetracosanoate = AMP + diphosphate + tetracosanoyl-CoA


name: beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Homo sapiens)


name: adenosine 3',5'-bisphosphate(in) + ADP(out) => adenosine 3',5'-bisphosphate(out) + ADP(in)


name: SORL1 transports APP(18-770) from endosome lumen to Golgi lumen (Homo sapiens)


name: Two NPFF receptors can bind neuropeptide FF (Danio rerio)


name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Mus musculus)


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Canis familiaris)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Dictyostelium discoideum)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Homo sapiens)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Caenorhabditis elegans)


name: H2O + L-isoleucine + NAD(+) <=> (S)-3-methyl-2-oxopentanoate + H(+) + NADH + NH4(+)


name: Collagen type XII degradation by MMP12 (Canis familiaris)


name: C1-Inh binds and inactivates C1r, C1s (Mus musculus)


name: SUMOylation of PIAS4 with SUMO1 (Rattus norvegicus)


name: GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) (Homo sapiens)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Saccharomyces cerevisiae)


name: PAK2 autophorylates (Xenopus tropicalis)


name: (4R)-hydroxysphinganine + 2-hydroxyhexacosanoyl-CoA = CoA + H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: FAD + H(+) + hexanoyl-CoA = (2E)-hexenoyl-CoA + FADH2


name: MYSM1 deubiquitinates Histone H2A (Homo sapiens)


name: CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Caenorhabditis elegans)


name: (S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate <=> 2-(3,5-dihydroxyphenyl)-2-oxoacetate + L-glutamate


name: 3-sulfino-L-alanine(out) + L-aspartate(in) => 3-sulfino-L-alanine(in) + L-aspartate(out)


name: (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoyl-CoA + O2


name: H2O + N-tetracosanoylsphinganine <=> sphinganine + tetracosanoate


name: DOLK phosphorylates DCHOL to DOLP (Rattus norvegicus)


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Homo sapiens)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Bos taurus)


name: hydrogen sulfide + NADP(+) + n sulfur => NADPH + (n+1) sulfur


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)


name: acetoacetate + succinyl-CoA = acetoacetyl-CoA + succinate


name: UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Sus scrofa)


name: a CDP-1,2-diacyl-sn-glycerol + diphosphate => a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+)


name: LIPC dimer hydrolyses TAG to DAG and FA (Rattus norvegicus)


name: 2-glyceryl-prostaglandin H2 => 2-glyceryl-prostaglandin E2


name: lithocholate + UDP-alpha-D-glucuronate = H(+) + lithocholoyl-3-O-(beta-D-glucuronate) + UDP


name: AH2 + cremeomycin = 2-hydroxy-4-methoxybenzoate + A + N2


name: ATP + docosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] = AMP + diphosphate + docosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: Cables link CDK5 and ABL1 (Homo sapiens)


name: PIP3 recruits AKT to the membrane (Saccharomyces cerevisiae)


name: (-)-lariciresinol + NADP(+) = (-)-pinoresinol + H(+) + NADPH


name: a long-chain fatty aldehyde + holo-[ACP] + NADP(+) <=> a long-chain fatty acyl-[ACP] + H(+) + NADPH


name: MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin (Homo sapiens)


name: 3-hydroxyisoheptadecanoyl-CoA + NADP(+) => 3-oxoisoheptadecanoyl-CoA + H(+) + NADPH


name: dopamine neurotransmitter receptor activity, coupled via Gs


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Homo sapiens)


name: EDNRA, EDNRB bind non-selective ERAs (Gallus gallus)


name: L-glutamine(out) + L-threonine(in) + Na(+)(out) => L-glutamine(in) + L-threonine(out) + Na(+)(in)


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Drosophila melanogaster)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Sus scrofa)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetylneuraminate => a ganglioside GM3 (d18:1(4E)) + H2O


name: (20S)-ginsenoside Rd + 2 H2O => (20S)-ginsenoside C-K + 2 D-glucose


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Sus scrofa)


name: 1,4-dihydroxy-2-naphthoate + all-trans-undecaprenyl diphosphate + H(+) = 2-demethylmenaquinol-11 + CO2 + diphosphate


name: Activation of Rap1 by cytosolic GEFs (Mus musculus)


name: Release of E3 from polyubiquitinated substrate (Rattus norvegicus)


name: P2Y5 receptor can bind to LPA (Xenopus tropicalis)


name: an aldopyranose + NAD(+) => aldono-1,5-lactone + H(+) + NADH


name: MAPKAPK2/3-mediated removal of PRC1.4 complex stimulates p14ARF transcription (Homo sapiens)


name: PIAS1 SUMOylates SATB2 with SUMO3 (Sus scrofa)


name: Digestion of triacylglycerols by extracellular PTL:colipase (Homo sapiens)


name: Orc1 is phosphorylated by cyclin A/CDK2 (Sus scrofa)


name: AcK-NFE2L2 and MAFK bind the GSTA1 gene (Homo sapiens)


name: (3R)-vestitone + NADP(+) <=> 2'-hydroxyformononetin + 2 H(+) + NADPH


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Xenopus tropicalis)


name: H(+) + NADPH + prostaglandin D2 => 11beta-prostaglandin F2 + NADP(+)


name: a ganglioside GM1 + GDP-beta-L-fucose => a ganglioside Fuc-GM1 + GDP + H(+)


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + presilphiperfolan-8beta-ol


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Sus scrofa)


name: Proinsulin translocates from the endoplasmic reticulum to the Golgi (Bos taurus)


name: p-T,Y MAPKs dimerize (Schizosaccharomyces pombe)


name: CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + octadecan-1-ol = 1-O-octadecyl (9Z)-octadecenoate + CoA


name: PIAS1,3 SUMOylate ESR1 with SUMO1 (Sus scrofa)


name: alpha-D-galactosyl-(1->3)-1D-myo-inositol + raffinose <=> myo-inositol + stachyose


name: CMP + 2 H(+) + 2 phosphate => CTP + 2 H2O


name: ATP + D-tagatofuranose 6-phosphate = ADP + D-tagatofuranose 1,6-bisphosphate + H(+)


name: PLCG2 translocates from cytosol to plasma membrane (Rattus norvegicus)


name: Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Bos taurus)


name: (R)-glycerate + ADP-alpha-D-glucose => (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Schizosaccharomyces pombe)


name: 4-nitroquinoline N-oxide + 2 H(+) + 2 NADH => 4-(hydroxyamino)quinoline N-oxide + H2O + 2 NAD(+)


name: (S)-2-hydroxyglutarate + O2 <=> 2-oxoglutarate + H2O2


name: L-alanine(in) + L-phenylalanine(out) = L-alanine(out) + L-phenylalanine(in)


name: glyoxylate dehydrogenase (acylating) activity


name: acetyl-CoA + holo-[ACP] = acetyl-[ACP] + CoA


name: AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate <=> A + semiviriditoxin


name: (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O => (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Bos taurus)


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Gallus gallus)


name: PIAS4 SUMOylates PARP1 with SUMO1 (Mus musculus)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + soppiline B = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + soppiline C


name: a globoside Gb4Cer + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside IV3GalNAc-Gb4Cer + H(+) + UDP


name: (9Z)-octadecenoate + 1,2-di-(9Z-octadecenoyl)-glycerol + H(+) => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O


name: Dissociation of CANX from nonameric complex (Homo sapiens)


name: Transport of MHC heterotrimer to ER exit site (Canis familiaris)


name: 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP (Gallus gallus)


name: RUNX1 binds ELF2 (Drosophila melanogaster)


name: a short-chain fatty acyl-CoA + H2O <=> a short-chain fatty acid + CoA + H(+)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Sus scrofa)


name: p-MAPK2/3 phosphorylates HSP27 (Drosophila melanogaster)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Saccharomyces cerevisiae)


name: Phosphorylation of LAT by p-SYK (Homo sapiens)


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)


name: MEMO1 binds RHOA:GTP:DIAPH1 (Caenorhabditis elegans)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Mus musculus)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Saccharomyces cerevisiae)


name: CBX4 SUMOylates BMI1 in PRC1 with SUMO1 (Homo sapiens)


name: 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + pyruvate => L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphoenolpyruvate


name: butanoate + NAD(+) => (2E)-2-butenoate + H(+) + NADH


name: DCN (decorin) degradation by MMP14 (Danio rerio)


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Homo sapiens)


name: ADP + beta-L-arabinose 1-phosphate + H(+) => ATP + L-arabinose


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Mus musculus)


name: Canonical WNT signaling through the atypical receptor RYK (Bos taurus)


name: intracellularly ATP-gated calcium channel activity


name: SEC31:SEC13 and v-SNARE recruitment (Gallus gallus)


name: DLD dimer dehydrogenates dihydrolipoyl (Mus musculus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Dictyostelium discoideum)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Gallus gallus)


name: Epsin family proteins bind ubiquitinated cargo (Canis familiaris)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Rattus norvegicus)


name: futalosine + H2O <=> dehypoxanthine futalosine + hypoxanthine


name: TBK1 phosphorylates STAT6 at Ser407 (Xenopus tropicalis)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane (Rattus norvegicus)


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Xenopus tropicalis)


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: D-ribitol 5-phosphate + NADP(+) => D-ribulose 5-phosphate + H(+) + NADPH


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Sus scrofa)


name: CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + sitosterol = (22S)-22-hydroxysitosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Drosophila melanogaster)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Drosophila melanogaster)


name: androst-4-ene-3,17-dione + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 1alpha-hydroxyandrost-4-ene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Sus scrofa)


name: apo-[peptidyl-carrier protein] + CoA => adenosine 3',5'-bisphosphate + H(+) + holo-[peptidyl-carrier protein]


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Bos taurus)


name: Transport of trimeric ENV precursor to Golgi apparatus (Homo sapiens)


name: ZNF420 binds TP53AIP1 gene (Homo sapiens)


name: p-PKR dimer phosphorylates DHX9 (Canis familiaris)


name: Ragulator binds Rag dimers (Mus musculus)


name: Dissociation of IRS-P from insulin receptor (Homo sapiens)


name: CoA + H(+) + O-(2-acetamidoethyl)-L-serine => acetyl-CoA + O-(2-aminoethyl)-L-serine


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Bos taurus)


name: (Z)-3-ureidoacrylate + H2O = (Z)-3-aminoacrylate + carbamate + H(+)


name: an aldehyde + H2O + NAD(+) <=> a carboxylate + 2 H(+) + NADH


name: guaiacol + O2 + reduced [NADH--hemoprotein reductase] => catechol + formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: Replication transcription complex binds SARS-CoV-2 genomic RNA (Homo sapiens)


name: DCC interaction with Netrin-1 (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O


name: SCF(beta-TrCP) ubiquitinates p-GLI2 (Homo sapiens)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Xenopus tropicalis)


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Canis familiaris)


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Drosophila melanogaster)


name: Exchange of oxygen with sulfur in MoCo (Drosophila melanogaster)


name: acetoin + CO2 => acetaldehyde + H(+) + pyruvate


name: Recruitment of Dna2 endonuclease (Saccharomyces cerevisiae)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Gallus gallus)


name: K+-independent Li+/Ca2+ exchanger transport (Saccharomyces cerevisiae)


name: HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Danio rerio)


name: 1,2-dihydro-alpha-santonin + NAD(+) => alpha-santonin + H(+) + NADH


name: an N-(acyl)-sphingosyl-1,3-cyclic phosphate + ethanolamine => an N-(acyl)-sphingosylphosphoethanolamine


name: ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA (Sus scrofa)


name: L-threonyl-[protein] + UDP-alpha-D-glucose = 3-O-(alpha-D-glucosyl)-L-threonyl-[protein] + H(+) + UDP


name: Arachidonic acid  is converted to 12-oxoETE by ALOX12 (Bos taurus)


name: PNPLA4 hydrolyzes retinyl palmitate (Rattus norvegicus)


name: bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer (Canis familiaris)


name: 2 glutathione amide + H2O2 => glutathione amide disulfide + 2 H2O


name: p-T,Y MAPK dimers translocate to nucleus (Gallus gallus)


name: RFC binding displaces Pol Alpha on the C-strand of the telomere (Sus scrofa)


name: 6-methoxycoumarin + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + scopoletin


name: Release of 40S and 60S subunits from the 80S ribosome  (Saccharomyces cerevisiae)


name: IL22 binds IL22RA1:JAK1 receptor complex (Gallus gallus)


name: (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2 => (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2


name: STAT3-dependent MIR-21 gene expression (Homo sapiens)


name: 3-oxo-L-alanyl-[sulfatase] + 5'-deoxyadenosine + 2 H(+) + hydrogen sulfide + L-methionine => H2O + L-cysteinyl-[sulfatase] + S-adenosyl-L-methionine


name: 2 Fe(II)-[cytochrome c] + H(+) + sulfur => 2 Fe(III)-[cytochrome c] + hydrogen sulfide


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Sus scrofa)


name: HTRA2 binds NDUFA13 (GRIM-19) (Homo sapiens)


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Saccharomyces cerevisiae)


name: H2O + neurotensin = L-isoleucyl-L-leucine + neurotensin(1-11)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Sus scrofa)


name: H2O + N-hexanoyl-sphinganine => hexanoate + sphinganine


name: H2O + L,L-cystathionine = 2-oxobutanoate + L-cysteine + NH4(+)


name: PANK4 hydrolyzes PPANT to pantetheine (Homo sapiens)


name: RHOD binds effectors at the endosome membrane (Gallus gallus)


name: NAD(+) + pyridoxine <=> H(+) + NADH + pyridoxal


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-(4R)-hydroxysphinganine = a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1-(10Z-heptadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: 5'-dehydroadenosine + H2O + O2 => 9-riburonosyladenine + H(+) + H2O2


name: Thrombin-activated PARs:Gq (active) dissociate (Mus musculus)


name: anthraniloyl-CoA + methanol <=> CoA + O-methyl anthranilate


name: PIAS1,4 SUMOylates BRCA1 with SUMO2,3 (Gallus gallus)


name: 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate synthase] + 9 CO2 + 9 CoA + 9 H2O + 18 NADP(+) => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 27 H(+) + 9 malonyl-CoA + 18 NADPH


name: monoatomic anion:monoatomic cation symporter activity


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Gallus gallus)


name: folate(in) + H(+)(in) = folate(out) + H(+)(out)


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Homo sapiens)


name: 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O => 24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2


name: (11R)-methyl carlactonoate + S-adenosyl-L-homocysteine => (11R)-carlactonoate + S-adenosyl-L-methionine


name: DKC1 binds SHQ1 (Dictyostelium discoideum)


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Plasmodium falciparum)


name: H2O + nicotinamide = NH4(+) + nicotinate


name: light-activated voltage-gated calcium channel activity


name: N-formyl-D-kynurenine => D-tryptophan + O2


name: Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Canis familiaris)


name: MTMR4 dephosphorylates SMAD2/3 (Bos taurus)


name: D-cellopentaose + O2 <=> D-cellopentaono-1,5-lactone + H2O2


name: acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase]


name: cortisone + O2 + reduced [NADPH--hemoprotein reductase] <=> 6beta-hydroxycortisone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Sus scrofa)


name: H2O + S-[(2E,6E,10E)-geranylgeranyl]-L-glutathione = L-glutamate + S-[(2E,6E,10E)-geranylgeranyl]-L-cysteinylglycine


name: Viral serpin blocks caspase-8 activity (Homo sapiens)


name: NEU2 hydrolyzes Neu5Ac from glycoconjugates (Rattus norvegicus)


name: IP receptor can bind prostacyclin (Bos taurus)


name: RANBP2 SUMOylates SP100 with SUMO1 (Sus scrofa)


name: RHOA:GTP translocates to the ER membrane (Xenopus tropicalis)


name: myricetin + S-adenosyl-L-methionine <=> H(+) + laricitrin + S-adenosyl-L-homocysteine


name: IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Mus musculus)


name: ATP + D-ribose 5-phosphate => 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)


name: holo-[peptidyl-carrier protein] + L-tryptophyl-5'-AMP = AMP + L-tryptophyl-[peptidyl-carrier protein]


name: 2,3-dihydroxybenzoate + H(+) = catechol + CO2


name: acetyl-CoA + dihydroxyacetone phosphate = 3-hydroxy-2,4-dioxopentyl phosphate + CoA


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Xenopus tropicalis)


name: 32-hydroxyeburicol + O2 + reduced [NADPH--hemoprotein reductase] <=> 32-oxoeburicol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Gallus gallus)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Bos taurus)


name: ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG (Mus musculus)


name: 1'-hydroxyversicolorone + H(+) + NADPH + O2 = (2S,3S)-versiconal hemiacetal acetate + H2O + NADP(+)


name: 2 5'-dehydroinosine + O2 <=> 2 9-riburonosylhypoxanthine + 2 H(+)


name: a 5'-end NTP-ribonucleotide-RNA + H2O => a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + diphosphate + H(+)


name: 7(1)-hydroxychlorophyllide a + H(+) + NADPH + O2 => chlorophyllide b + 2 H2O + NADP(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O => 1,2-dihexadecanoyl-sn-glycerol + H(+) + phosphoethanolamine


name: beta-D-fructose 1,6-bisphosphate <=> D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-mannose 1-phosphate = (2R)-3-phosphoglycerate + alpha-D-mannose 1,6-bisphosphate + H(+)


name: H(+) + H2O + N-terminal L-asparaginyl-[protein] <=> N-terminal L-aspartyl-[protein] + NH4(+)


name: (2E)-geranial + H(+) + NADPH + O2 <=> (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate + H2O + NADP(+)


name: C3PO hydrolyzes cleaved passenger strand (Xenopus tropicalis)


name: a globoside Gb3Cer + UDP-alpha-D-galactose = a globoside GalGb3Cer + H(+) + UDP


name: HIPK2 phosphorylates TP53 (Mus musculus)


name: aminodiacetate + FMN + glyoxylate + H2O => FMNH2 + nitrilotriacetate + O2


name: EPS15 and HGS bind CBL-monoubiquitinated MET engaged with Listeria InlB (Homo sapiens)


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Bos taurus)


name: beta-D-gentiobiosyl crocetin + UDP-alpha-D-glucose = beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP


name: Association of Golgi  transport vesicles with microtubules (Canis familiaris)


name: RAC2:GTP binds NOX2 complex (Danio rerio)


name: CERT1-2 complex binds ceramide (Drosophila melanogaster)


name: H2O + N-(long-chain fatty acyl)ethanolamine => a long-chain fatty acid + ethanolamine


name: S2P hydrolyzes SREBP1A,1C,2 (Xenopus tropicalis)


name: 4-epi-eremophilene + O2 + reduced [NADPH--hemoprotein reductase] = 4-epi-eremophilene-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Schizosaccharomyces pombe)


name: Expression of SALL1 in metanephric mesenchyme (Homo sapiens)


name: CO2 + H2O + uridine-5'-carboxamide => (5'S,6'R)-C-glycyluridine + O2


name: a ribonucleoside 5'-phosphate + ATP <=> a ribonucleoside 5'-diphosphate + ADP


name: ATP + H2O + iron(III) dicitrate(out) <=> ADP + H(+) + iron(III) dicitrate(in) + phosphate


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Xenopus tropicalis)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 <=> 15-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate


name: 2 H(+) + H2O + N-carbamoylputrescine => CO2 + NH4(+) + putrescine


name: glycerol-1-phosphate dehydrogenase (NAD+) activity


name: NAD(+) + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H(+) + NADH


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Homo sapiens)


name: 8 H(+) + 10 malonyl-CoA => 10 CO2 + 10 CoA + 2 H2O + tetracenomycin F2


name: D-xylofuranose + NADP(+) <=> D-xylono-1,4-lactone + H(+) + NADPH


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Rattus norvegicus)


name: 1-(5-phospho-beta-D-ribosyl)-ATP + H2O <=> 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)


name: fibrin multimer -> fibrin multimer, crosslinked + NH4+ (Sus scrofa)


name: Transfer of LPS onto TLR4 (Gallus gallus)


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Canis familiaris)


name: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)


name: N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: Activation of Ca2+ activated Potassium channels with large conductance (Gallus gallus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Homo sapiens)


name: Expression of Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) (Homo sapiens)


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Xenopus tropicalis)


name: Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) (Homo sapiens)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Xenopus tropicalis)


name: 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP <=> AMP + diphosphate + H(+) + staphyloferrin B


name: 1-pyrroline-2-carboxylate + H2O => trans-3-hydroxy-L-proline


name: flavokermesate + UDP-alpha-D-glucose <=> flavokermesate 7-C-beta-D-glucoside + 2 H(+) + UDP


name: 1D-myo-inositol hexakisphosphate + O-diphospho-L-seryl-[protein] => 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + O-phospho-L-seryl-[protein]


name: (S)-2,3-dihydrodipicolinate + H(+) + 2 H2O => L-aspartate 4-semialdehyde + pyruvate


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Canis familiaris)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2 = (2S)-3-(4-hydroxyphenyl)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2


name: cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Mus musculus)


name: Neurofascin binds Ankyrin-G (Homo sapiens)


name: H2O + mycophenolic acid O-acyl-beta-D-glucuronide = D-glucuronate + H(+) + mycophenolate


name: "mycophenolic acid acyl-glucuronide esterase"


name: Spermidine  => N-acetylated spermidine (Mus musculus)


name: 6-tuliposide A <=> D-glucose + tulipalin A


name: 7-cyano-7-deazaguanine + guanosine(15) in tRNA <=> 7-cyano-7-carbaguanosine(15) in tRNA + guanine


name: (2S)-ethylmalonyl-CoA + NADP(+) = (2E)-butenoyl-CoA + CO2 + NADPH


name: N-dodecanoyl-(2S)-hydroxyglycine => dodecanamide + glyoxylate


name: ATP + D-allose(out) + H2O <=> ADP + D-allose(in) + H(+) + phosphate


name: MKL1 translocates from cytosol to the nucleus (Drosophila melanogaster)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Bos taurus)


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Bos taurus)


name: 2-oxoglutarate + heptyl sulfate + O2 <=> CO2 + H(+) + heptanal + succinate + sulfate


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Sus scrofa)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] = 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin]


name: FGFR1b binds to FGF (Drosophila melanogaster)


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Sus scrofa)


name: DHNTP is dephosphorylated by PTPS to PTHP (Rattus norvegicus)


name: RIP2 is K63 polyubiquitinated (Canis familiaris)


name: 2-oxobutanoate + L-histidine => (2S)-2-aminobutanoate + 3-(imidazol-5-yl)pyruvate


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Dictyostelium discoideum)


name: [protein]-C-terminal glycine + NAD(+) => [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide


name: a long-chain fatty acid(out) => a long-chain fatty acid(in)


name: a cardiolipin + H2O => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Drosophila melanogaster)


name: 7,8-dihydroxycoumarin + S-adenosyl-L-methionine => 7-hydroxy-8-methoxycoumarin + H(+) + S-adenosyl-L-homocysteine


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Drosophila melanogaster)


name: (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + CO2 + CoA


name: ATP + L-threonyl-[tau protein] <=> ADP + H(+) + O-phospho-L-threonyl-[tau protein]


name: CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Bos taurus)


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Schizosaccharomyces pombe)


name: 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + NAD(+) <=> CO2 + cycloeucalenone + NADH


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Saccharomyces cerevisiae)


name: 7-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Canis familiaris)


name: EHMT1:EHMT2 dimethylates TP53 (Homo sapiens)


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Rattus norvegicus)


name: CYP21A2 oxidises 17HPROG (Rattus norvegicus)


name: 2-cis,4-trans-xanthoxin + NAD(+) <=> 2-cis-(+)-abscisic aldehyde + H(+) + NADH


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O => diphosphate + preaspterpenacid acid I


name: a 2-(omega-methylsulfanyl)alkylmalate = a 3-(omega-methylsulfanyl)alkylmalate


name: SLC50A1 transports Glc from cytosol to extracellular region (Homo sapiens)


name: 3-methyl-2-oxobutanoate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] <=> CO2 + N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]


name: MSX2 binds RUNX2 gene promoter (Homo sapiens)


name: L-alanine + oxomalonate <=> aminomalonate + pyruvate


name: methylazoxymethanol + UDP-alpha-D-glucose <=> cycasin + H(+) + UDP


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Homo sapiens)


name: Plk1-mediated phosphorylation of Nlp (Xenopus tropicalis)


name: L-alanine + phosphonoacetaldehyde => (2-aminoethyl)phosphonate + pyruvate


name: an N-(fatty acyl)-L-leucine + H2O = a fatty acid + L-leucine


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine => di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP


name: a medium chain fatty acid + 2 H(+) + NADH => a medium-chain fatty aldehyde + H2O + NAD(+)


name: 2-oxoglutarate + O2 + prekainate => CO2 + H2O + kainate + succinate


name: 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine


name: HIPK2 phosphorylates RUNX1 (Drosophila melanogaster)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Bos taurus)


name: [thioredoxin]-dithiol + L-methionine (S)-S-oxide => [thioredoxin]-disulfide + H2O + L-methionine


name: HTR1A binds HTR1A antagonists (Gallus gallus)


name: (4R)-hydroxysphinganine + docosanoyl-CoA => CoA + H(+) + N-docosanoyl-(4R)-hydroxysphinganine


name: 3 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) = 3 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: 4-(trifluoromethyl)benzyl alcohol + NAD(+) <=> 4-(trifluoromethyl)benzaldehyde + H(+) + NADH


name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Mus musculus)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Caenorhabditis elegans)


name: USP30 binds ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)


name: L-alanine + taurocholate <=> L-alanocholate + taurine


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Gallus gallus)


name: RAC1:GTP binds NOX3 complex (Bos taurus)


name: bPIX exchanges GTP for GDP on RAC, activating it (Caenorhabditis elegans)


name: H2O + L-homocysteine + oxidized 2[4Fe-4S]-[ferredoxin] => 3 H(+) + hydrogen sulfide + L-aspartate 4-semialdehyde + reduced 2[4Fe-4S]-[ferredoxin]


name: 3 Na(+)(out) + succinate(out) = 3 Na(+)(in) + succinate(in)


name: NADP(+) + pyridoxine <=> H(+) + NADPH + pyridoxal


name: Interleukin-1 family are secreted (Homo sapiens)


name: TPMT transfers methyl group to 6TIMP, forming 6MeTIMP (Homo sapiens)


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Mus musculus)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Sus scrofa)


name: (2-hydroxyphenyl)acetate + CO2 => 3-phenylpyruvate + O2


name: H(+)(out) + L-histidine(out) = H(+)(in) + L-histidine(in)


name: ATP + glutathione(in) + H2O => ADP + glutathione(out) + H(+) + phosphate


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Canis familiaris)


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Canis familiaris)


name: NADP(+) + nicotinate = nicotinamide + nicotinate-adenine dinucleotide phosphate


name: mycophenolyl-CoA + propanoyl-CoA <=> (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + CoA


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Schizosaccharomyces pombe)


name: Recruitment of PAK to NCK (Homo sapiens)


name: Association of procollagen type XXIV (Canis familiaris)


name: cytidine(839) in 12S rRNA + S-adenosyl-L-methionine => H(+) + N(4)-methylcytidine(839) in 12S rRNA + S-adenosyl-L-homocysteine


name: FMO2:FAD:Mg2+ S-oxidises MTZ (Homo sapiens)


name: 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate (Gallus gallus)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: ABL1 phosphorylates YAP1 (Caenorhabditis elegans)


name: PGLYRP3,4 binds bacterial peptidoglycan (Mus musculus)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Rattus norvegicus)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Bos taurus)


name: STAT3 is phosphorylated downstream of active ALK (Homo sapiens)


name: H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] => (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Danio rerio)


name: 2 H(+) + 3 N-(2,3-dihydroxybenzoyl)-L-serine => enterobactin + 3 H2O


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Rattus norvegicus)


name: CYP21A2 21-hydroxylates PROG (Homo sapiens)


name: Autoglucosylation of GYG2 complexed with GYS2-a (Canis familiaris)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Danio rerio)


name: Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Gallus gallus)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Bos taurus)


name: D-allo-threonine => acetaldehyde + glycine


name: PDK isozymes phosphorylate PDHC subunit E1 (Mus musculus)


name: Phosphorylated Cdc6 is exported from the nucleus (Homo sapiens)


name: H2O + L-glutamate 5-semialdehyde + NAD(+) => 2 H(+) + L-glutamate + NADH


name: a fatty acyl-[ACP] + sn-glycerol 3-phosphate => a 1-acyl-sn-glycero-3-phosphate + holo-[ACP]


name: SUMOylation of DDX17 with SUMO1 (Dictyostelium discoideum)


name: MRN complex binds DNA double strand breaks (Homo sapiens)


name: (24S)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Bos taurus)


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Mus musculus)


name: PRTPRF, PTPRS, PTPRD bind LRRC4B (Homo sapiens)


name: dimethyl sulfone + FMNH2 + O2 => FMN + formaldehyde + 2 H(+) + H2O + methanesulfinate


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Schizosaccharomyces pombe)


name: acetyl-CoA + 5 H(+) + 6 malonyl-CoA => 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + 6 CO2 + 7 CoA + H2O


name: RHOG GAPs stimulate RHOG GTPase activity (Xenopus tropicalis)


name: (9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: vWF binds to collagen (Canis familiaris)


name: acetylenedicarboxylate + H(+) + H2O = CO2 + pyruvate


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol <=> 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Mus musculus)


name: D-leucine + H2O + O2 <=> 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: 1,2,3-tributanoylglycerol + H2O <=> butanoate + dibutanoylglycerol + H(+)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out) => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in)


name: p-4Y-PLCG1 dissociates from activated FGFR3 (Homo sapiens)


name: a carboxylate + ATP + H(+) = an acyl-AMP + diphosphate


name: hexanoyl-CoA + tyramine => CoA + H(+) + N-hexanoyltyramine


name: transmitter-gated monoatomic ion channel activity


name: mRNP complex dissociates from cytosolic face of NPC (Gallus gallus)


name: GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate <=> GDP + H(+) + methyl 8-{[alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc]oxy}nonanoate


name: RIC1:RGP1 recruits RAB6:GDP to the TGN (Schizosaccharomyces pombe)


name: Cleavage of p-STK3 (p-MST2) by caspase 3 (Drosophila melanogaster)


name: tBID activates BAK protein (Mus musculus)


name: Reduction of disulphide bonds in MHC II antigens (Rattus norvegicus)


name: ATP + L-glutamate + L-glutamyl-[beta-tubulin] = ADP + gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + H(+) + phosphate


name: an N-alkylglycine + H2O + O2 = an alkylamine + glyoxylate + H2O2


name: SCD desaturates ST-CoA to OLE-CoA (Schizosaccharomyces pombe)


name: 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AH2 + O2 => (2R)-2-(4-aminophenyl)-L-seryl-[peptidyl-carrier protein] + A + H2O


name: ESR-associated SRC autophosphorylates (Danio rerio)


name: mannose-1-phosphate guanylyltransferase (GDP) activity


name: Phosphorylation of USP8 by P-AKT (Mus musculus)


name: Association of Ku heterodimer with ends of DNA double-strand break (Homo sapiens)


name: D-glucurono-3,6-lactone + H(+) + NADPH => L-gulono-1,4-lactone + NADP(+)


name: (E)-2,4-dihydroxycinnamoyl-CoA <=> CoA + umbelliferone


name: Proteasome degrades polyubiquitinated PTEN (Dictyostelium discoideum)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: a ganglioside GM2 (d18:1(4E)) + H2O => a ganglioside GA2 (d18:1(4E)) + N-acetylneuraminate


name: SOX17, TFAP2C, and PRDM1 (BLIMP1) bind the NANOS3 gene (Homo sapiens)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Caenorhabditis elegans)


name: PGH2 is isomerised to PGD2 by HPGDS (Sus scrofa)


name: 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Tetrastatin binds integrin alphaVbeta3 (Xenopus tropicalis)


name: Formation of HIF:CBP:p300 complex at promoters (Sus scrofa)


name: gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)


name: Activation of ISG15 by UBA7 E1 ligase (Plasmodium falciparum)


name: a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA => a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA


name: CBL ubiquitinates FRS2 and FGFR1 (Bos taurus)


name: L-arginine(in) + L-leucine(out) = L-arginine(out) + L-leucine(in)


name: Relaxin receptor 2 binds relaxin 2 and INSL3 (Canis familiaris)


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Gallus gallus)


name: ANKLE2 binds VRK1,(VRK2) (Gallus gallus)


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Saccharomyces cerevisiae)


name: FeHM dissociates from MetHb (Bos taurus)


name: H2O + NADP(+) + pentylamine <=> H(+) + NADPH + NH4(+) + pentanal


name: Insulin receptor de-phosphorylation (Xenopus tropicalis)


name: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate


name: alfacalcidol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> calcitriol + H2O + 2 oxidized [adrenodoxin]


name: RPA binds to the Flap (Rattus norvegicus)


name: non-membrane spanning protein tyrosine kinase activity


name: Persulfide sulfur is dioxygenated (Xenopus tropicalis)


name: (2S)-2-nitrosobutanedioate + H(+) + NADPH + O2 <=> 2-nitrobutanedioate + H2O + NADP(+)


name: beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B3) => H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3)


name: "galactan exo-1,6-beta-galactobiohydrolase (non-reducing end)"


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Rattus norvegicus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate => dimethylallyl diphosphate + 4 isopentenyl diphosphate


name: mito-STARD7 transports Q10 to outer mitochondrial membrane (Xenopus tropicalis)


name: CDK2 phosphorylates TP53 (Rattus norvegicus)


name: Activated FGFR1 binds FRS2 (Rattus norvegicus)


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Gallus gallus)


name: oxLDL:CD36 binds TLR4:TLR6 (Gallus gallus)


name: (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O => (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate


name: Dissociation of the Gi alpha:G olf complex (Mus musculus)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Homo sapiens)


name: AMP + CoA + diphosphate + 2 H(+) + tenuazonic acid => acetoacetyl-CoA + ATP + L-isoleucine


name: Activation of Rap1 by membrane-associated GEFs (Rattus norvegicus)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Danio rerio)


name: Furin cleaves pro-protein Z to protein Z (Mus musculus)


name: POM121 binds the Nup107-Nup160 complex (Homo sapiens)


name: CTP(in) + ITP(out) => CTP(out) + ITP(in)


name: Activated FGFR3:p-SHC1 binds GRB2:SOS1 (Mus musculus)


name: O2 + paromamine = 6'-oxoparomamine + H2O2


name: p-Y-STATs translocate to nucleus (Caenorhabditis elegans)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Rattus norvegicus)


name: HP1 alpha binds Histone H3K9(me)3 (Sus scrofa)


name: 7-dehydrocholesterol + hnu => previtamin D3


name: 3-dehydro-L-gulonate + NAD(+) => 2,3-dioxo-L-gulonate + H(+) + NADH


name: D-maltopentaose + H2O = alpha-D-glucose + D-maltotetraose


name: PP2A-B56 dephosphorylates centromeric cohesin (Gallus gallus)


name: Translocation of p-IRF7:p-IRF7 to nucleus (Xenopus tropicalis)


name: p-Y701-STAT1 dimerizes (Drosophila melanogaster)


name: H(+)(out) + L-galactose(out) <=> H(+)(in) + L-galactose(in)


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Plasmodium falciparum)


name: beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3) => H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1)


name: 1-hexadecanoyl-2-[9-hydroperoxy-(10E-octadecenoyl)]-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-hydroperoxy-10E-octadecenoate + H(+)


name: 3-hydroxydocosanoyl-CoA + NADP(+) => 3-oxodocosanoyl-CoA + H(+) + NADPH


name: H(+)(in) + L-lysine(in) => H(+)(out) + L-lysine(out)


name: 2 ATP + butan-2-one + 3 H2O + hydrogencarbonate = 3-oxopentanoate + 2 AMP + 4 H(+) + 4 phosphate


name: 6-phospho-D-gluconate + NADP(+) <=> 6-phospho-2-dehydro-D-gluconate + H(+) + NADPH


name: keto-D-fructose 6-phosphate => D-allulose 6-phosphate


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Caenorhabditis elegans)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Homo sapiens)


name: TetraHCA is translocated from the mitochondrial matrix to the cytosol (Homo sapiens)


name: NUDT16 hydrolyses IDP to IMP (Bos taurus)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Saccharomyces cerevisiae)


name: SUMOylation of PML with SUMO3 (Danio rerio)


name: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 (Mus musculus)


name: a ubiquinone + keto-D-fructose = 5-dehydro-D-fructose + a ubiquinol


name: NPAS4 stimulates IQSEC3 gene expression (Homo sapiens)


name: KAT5 acetylates ATM at DNA DSBs (Gallus gallus)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Sus scrofa)


name: (S)-malate(in) + sulfate(out) = (S)-malate(out) + sulfate(in)


name: (2S)-pristanoyl-CoA + O2 <=> (2E)-pristenoyl-CoA + H2O2


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GA2 (d18:1(4E)) + H(+) + UDP


name: I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol (Bos taurus)


name: (3S)-hydroxyoctadecanoyl-CoA + NAD(+) => 3-oxooctadecanoyl-CoA + H(+) + NADH


name: phycoerythrobilin-L-cysteinyl(84)-[C-phycoerythrin alpha-subunit] = (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[C-phycoerythrin alpha-subunit]


name: ATP + hexadecanoate + holo-[ACP] <=> AMP + diphosphate + hexadecanoyl-[ACP]


name: CMP(out) + CMP-N-acetyl-beta-neuraminate(in) = CMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: Transfer of NEDD8 to AcM-UBE2M (Rattus norvegicus)


name: H(+) + H2O + N,N-dihydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase] => N-hydroxy-L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase]


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) <=> 4,5-dihydroxyphthalate + H(+) + NADH


name: glyoxylate + oxaloacetate => 3-oxalomalate


name: (10E)-octadecenoate + H2O <=> 10-hydroxyoctadecanoate


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Rattus norvegicus)


name: (2S)-2-aminobutanoate + glyoxylate => 2-oxobutanoate + glycine


name: (3R)-hydroxytetradecanoyl-[ACP] + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = H(+) + holo-[ACP] + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine


name: Syndecans 1, 2, 4, (3) bind FGF2 (Homo sapiens)


name: a 1,2-diacyl-sn-glycerol + a glycerophospholipid => a monoacylglycerophospholipid + a triacyl-sn-glycerol


name: IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Gallus gallus)


name: Cytosolic PP2A dephosphorylates phosphorylated PER complexed with TIM and DCO (Drosophila melanogaster)


name: (2R)-3-phospho-glyceroyl phosphate <=> (2R)-2,3-bisphosphoglycerate + H(+)


name: (1S,2S)-pseudoephedrine + NAD(+) = (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: all-trans-retinal + H2O + NAD(+) = all-trans-retinoate + 2 H(+) + NADH


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Sus scrofa)


name: (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-tetrahomomethionine


name: 1-(9Z-octadecenoyl)-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate


name: agmatine + H2O + O2 <=> H2O2 + N-amidino-(2R)-hydroxypyrrolidine + NH4(+)


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene + A => 1'-hydroxy-demethylspheroidene + AH2


name: OCT2 mediates tubular secretion of organic cations in the kidney (Gallus gallus)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Canis familiaris)


name: Formation of Cyclin A:Cdk2 complexes (Gallus gallus)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Drosophila melanogaster)


name: propan-2-ol:coenzyme F420 oxidoreductase activity


name: (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,12Z,15Z)-hexadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: an anthocyanidin 3-O-sophoroside + 2 H(+) + UDP => an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose


name: Mitochondrial FPGS-1 transforms THF to THFPG (Rattus norvegicus)


name: Transport of GAG to the Plasma Membrane (Homo sapiens)


name: GEFs activate RhoA,B,C (Caenorhabditis elegans)


name: VD3 dissociates from GC (Rattus norvegicus)


name: (2E)-butenoyl-[ACP] + AMP + H(+) => (2E)-but-2-enoyl-AMP + holo-[ACP]


name: Engulfment of particulate antigen into phagocytic vesicle (Rattus norvegicus)


name: 4 H(+) + 5 malonyl-CoA <=> 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + 5 CoA + H2O


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine


name: 3-(2,4-dioxopentyl)-3,6,8,9-tetrahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2 = 3-(2,4-dioxopentyl)-2,3,6,8,9-pentahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+)


name: H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine => adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine


name: (+)-copalyl diphosphate = (12E)-labda-8(17),12,14-triene + diphosphate


name: [DsbB protein]-dithiol + [protein]-disulfide => [DsbD protein]-disulfide + [protein]-dithiol


name: AKR1B1 reduces Glc to D-sorbitol (Danio rerio)


name: 2 a 2-acyl-sn-glycero-3-phosphocholine <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: ATP + Cu(+)(in) + H2O => ADP + Cu(+)(out) + H(+) + phosphate


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Caenorhabditis elegans)


name: (13Z)-docosenoate + NH4(+) => (13Z)-docosenamide + H2O


name: H2O + L-2-aminopentanoate + O2 <=> 2-oxopentanoate + H2O2 + NH4(+)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + cholesterol = 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoate


name: (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase] <=> 3beta-hydroxycostunolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH => 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+)


name: SIRT1 deacetylates HSF1 (Canis familiaris)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Mus musculus)


name: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] <=> an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-cis-N-methyltetrahydrothalifendine + O2 + reduced [NADPH--hemoprotein reductase] <=> 7-hydroxy-8-methoxy-11-methyl-17,19-dioxa-11-azatetracyclo[12.7.0.0(4,9).0(16,20)]henicosa-1(21),4(9),5,7,14,16(20)-hexaen-2-one + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + sphinganine 1-phosphate <=> phosphate + sphinganine


name: chloride(out) + L-lysine(out) + 2 Na(+)(out) = chloride(in) + L-lysine(in) + 2 Na(+)(in)


name: Interleukin-1 family are secreted (Bos taurus)


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Canis familiaris)


name: Enhanced autophagosome formation (Homo sapiens)


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Canis familiaris)


name: 2-methylpentanoate + ATP + CoA = 2-methylpentanoyl-CoA + AMP + diphosphate


name: ASAP1 stimulates GTPase activity of ARF4 (Sus scrofa)


name: SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Gallus gallus)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Mus musculus)


name: acetyl-CoA + H2O + pyruvate => (3R)-citramalate + CoA + H(+)


name: GNRHR binds chemical antagonists (Gallus gallus)


name: H(+) + menadione + NADPH => menadiol + NADP(+)


name: ALPK1:ADP-heptose binds TIFA (Canis familiaris)


name: EP1 subtype prostaglandin E2 receptor binding


name: 2 ATP + 2 H2O + protochlorophyllide a + reduced 2[4Fe-4S]-[ferredoxin] => 2 ADP + chlorophyllide a + oxidized 2[4Fe-4S]-[ferredoxin] + 2 phosphate


name: IRAK1 binds to MYD88 within the IL1R complex (Rattus norvegicus)


name: PGM2:Mg2+ isomerises R1P to R5P (Xenopus tropicalis)


name: S-adenosyl-L-methionine + uridine(2791) in 21S rRNA => 2'-O-methyluridine(2791) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine


name: NADH + oxidized 2[4Fe-4S]-[ferredoxin] => H(+) + NAD(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-decanoyl ethanolamine => H2O + N-decanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine


name: H(+) + homogentisate + phytyl diphosphate <=> 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate


name: acetyl-CoA + eicosanoyl-CoA <=> 3-oxodocosanoyl-CoA + CoA


name: CYP4F8 19-hydroxylates PGH2 (Rattus norvegicus)


name: D-methionine + H2O + O2 = 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+)


name: (+)-epi-isozizaene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (5S)-albaflavenol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 3-O-acetyl-4'-O-demethylpapaveroxine + H(+) => (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine


name: (2E,6E)-farnesyl diphosphate = diphosphate + germacrene D


name: dichloromethane + H2O => 2 chloride + formaldehyde + 2 H(+)


name: alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-3,6-dideoxy-alpha-D-mannose <=> alpha-D-Tyv-(1->3)-alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Canis familiaris)


name: USP8 deubiquitinates LRIG1 (Canis familiaris)


name: GOPC promotes translocation of CFTR to lysosomes (Canis familiaris)


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Gallus gallus)


name: n fibrin monomers -> fibrin multimer (Rattus norvegicus)


name: (20S)-ginsenoside Rg3 + UDP-alpha-D-glucose <=> (20S)-ginsenoside Rd + H(+) + UDP


name: TBC1D10A (EPI64) binds ARF6:GTP (Bos taurus)


name: D-cellobiose + O2 => D-cellobiono-1,5-lactone + H2O2


name: PSAP(195-273) forms a dimer (Sus scrofa)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Danio rerio)


name: "Linked to the hydrolysis of diphosphate"


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Homo sapiens)


name: n H(+)(out) + serotonin(in) => n H(+)(in) + serotonin(out)


name: USP19 deubiquitinates RNF123 (Homo sapiens)


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: (+)-artemisinic aldehyde + H(+) + NADH => (+)-artemisinic alcohol + NAD(+)


name: Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) (Homo sapiens)


name: Thrombin-activated PARs activate G12/13 (Canis familiaris)


name: H(+)(out) + L-threonine(in) => H(+)(in) + L-threonine(out)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Rattus norvegicus)


name: 9,9'-di-cis-zeta-carotene + a quinone => 7,9,9'-tri-cis-neurosporene + a quinol


name: IL12B translocates from the cytosol to the extracellular region (Bos taurus)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Danio rerio)


name: acetyl-CoA + propanoate => acetate + propanoyl-CoA


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Rattus norvegicus)


name: MRN bound to shortened telomeres activates ATM (Bos taurus)


name: H(+)(out) + inosine(in) => H(+)(in) + inosine(out)


name: STK11 (LKB1) phosphorylates NUAK1 (Homo sapiens)


name: acyl-phosphate glycerol-3-phosphate acyltransferase activity


name: (9Z,12Z)-octadecadienoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2,2-dihydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2-hydroxyspirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Palmostatin B binds RAS depalmitoylases (Dictyostelium discoideum)


name: 3-aminopentane + H2O + NAD(+) <=> H(+) + NADH + NH4(+) + pentan-3-one


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Drosophila melanogaster)


name: formyl-CoA + H2O => formate + CoASH (Homo sapiens)


name: AMP + H2O => IMP + NH4+ (AMPD) (Homo sapiens)


name: 2 H(+) + 2 NADPH + 2 O2 + tetracenomycin B2 <=> 8-demethyltetracenomycin C + H2O + 2 NADP(+)


name: LC3 de-lipidation by ATG4 (Dictyostelium discoideum)


name: HMGCR dimer reduces bHMG-CoA to MVA (Caenorhabditis elegans)


name: 8 H(+) + heme b + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> biliverdin IXalpha + CO + Fe(2+) + 3 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: H(+)(out) + L-cysteine(in) + Na(+)(in) => H(+)(in) + L-cysteine(out) + Na(+)(out)


name: Thrombin binding to GP1b:IX:V (Bos taurus)


name: H2O + N(1)-acetylspermine + O2 = 3-acetamidopropanal + H2O2 + spermidine


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Drosophila melanogaster)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Rattus norvegicus)


name: Histone acetyltransferases are recruited to the TFF1 gene (Xenopus tropicalis)


name: L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 (Homo sapiens)


name: Hydrolysis of PIP2 by PLCG (Rattus norvegicus)


name: Myristoylated NPHP3 translocates into the ciliary membrane (Rattus norvegicus)


name: Discoidal HDL binds membrane-associated free cholesterol (Mus musculus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Plasmodium falciparum)


name: alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + CMP + H(+) => alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + CMP-N-acetyl-beta-neuraminate


name: ATP + beta-alanine + L-ornithine <=> ADP + beta-alanyl-L-ornithine + H(+) + phosphate


name: protein-arginine omega-N symmetric methyltransferase activity


name: (1R,2S,4R)-borneol + NAD(+) = (1R,4R)-camphor + H(+) + NADH


name: MADD exchanges GTP for GDP on RAB27 (Gallus gallus)


name: rhamnetin + S-adenosyl-L-methionine = 7,4'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine


name: Defective SLC5A5 does not cotransport Na+ with I- from extracellular region to cytosol (Homo sapiens)


name: The IFT-A complex recruits TULP3 (Rattus norvegicus)


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol (Homo sapiens)


name: MBTPS2 (S2P) cleaves CREB3L1 (Homo sapiens)


name: miR-33 binds to the 3'UTR of the ABCA1 mRNA (Homo sapiens)


name: LIPC dimer hydrolyses TAG to DAG and FA (Sus scrofa)


name: Recruitment of GRB2:SOS to p-5Y-LAT (Rattus norvegicus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)


name: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(+) => 2-oxo-2H-pyran-4,6-dicarboxylate + H2O


name: D-mannose 6-phosphate => alpha-D-mannose 1-phosphate


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Homo sapiens)


name: BAR domain proteins recruit dynamin (Sus scrofa)


name: (S)-4-hydroxymandelate + CO2 => 3-(4-hydroxyphenyl)pyruvate + O2


name: ATP + cholate(in) + H2O => ADP + cholate(out) + H(+) + phosphate


name: PEX7 binds cargo proteins containing PTS2 (Dictyostelium discoideum)


name: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] <=> acetate + androst-4-ene-3,17-dione + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-glutamate 5-semialdehyde <=> (S)-1-pyrroline-5-carboxylate + H(+) + H2O


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Canis familiaris)


name: Activation of conventional Protein Kinase C (Bos taurus)


name: a guanosine in mRNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in mRNA + S-adenosyl-L-homocysteine


name: TFAP2A,TFAP2C homodimers bind the CGA gene (Homo sapiens)


name: 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP = AMP + diphosphate + H(+) + staphyloferrin B


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H2O <=> 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + H(+) + phosphate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => (9Z)-octadecenoate + H(+) + sn-glycerol 3-phosphocholine


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Rattus norvegicus)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Rattus norvegicus)


name: MLCL transports from the IM to the ER (Homo sapiens)


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Dictyostelium discoideum)


name: MT-MMPs are sorted to the plasma membrane (Danio rerio)


name: UCHL1, UCHL3 cleave ubiquitin adducts (Sus scrofa)


name: beta-L-fucose + NADP(+) => H(+) + L-fucono-1,5-lactone + NADPH


name: (S)-nicotine + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + 2 H(+) + N-methylmyosmine


name: 13-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: Defective NPC does not transport GCK1:GKRP from cytosol to nucleoplasm (Homo sapiens)


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] => atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: ROCK1,ROCK2 are activated (Homo sapiens)


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA = [O(7),N-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Canis familiaris)


name: solasodine + UDP-alpha-D-glucose => H(+) + solasodine 3-beta-D-glucoside + UDP


name: 5-hydroxyuridine(34) in tRNA + carboxy-S-adenosyl-L-methionine = 5-carboxymethoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: Release Of ADP From Myosin (Caenorhabditis elegans)


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)


name: (+)-piperitol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (+)-pinoresinol + O2 + reduced [NADPH--hemoprotein reductase]


name: L-arginine + S-adenosyl-L-methionine = H(+) + N(omega)-methyl-L-arginine + S-adenosyl-L-homocysteine


name: PPO oxidises PPGEN9 to PRIN9 (Homo sapiens)


name: p-Y693-STAT4 dimerizes (Drosophila melanogaster)


name: FAM83B, (FAM83A, FAM83D) bind EGFR (Xenopus tropicalis)


name: H2O + O2 + spermine => H2O2 + NH4(+) + spermine monoaldehyde


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Homo sapiens)


name: Truncated Alpha-1-Microglobulin binds heme (Danio rerio)


name: a quinone + an aldehyde + H2O => a carboxylate + a quinol + H(+)


name: 4-(methylamino)butanoate + H2O + O2 = H2O2 + methylamine + succinate semialdehyde


name: 6-methylsalicylate + H(+) <=> 3-methylphenol + CO2


name: ARL2:GTP:ARL2BP binds SLC25A4 (Mus musculus)


name: LIPs hydrolyze TG to DAG and LCFA (Bos taurus)


name: Cdc45 associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)


name: BRAF autophosphorylates downstream of RAP1 and NGF (Sus scrofa)


name: CYP1A2, 3A4 oxidise AFB1 to AFNBO (Sus scrofa)


name: Slo3 Potassium Transport (Dictyostelium discoideum)


name: SLC4A4 cotransports Na+ with 3HCO3- (Caenorhabditis elegans)


name: AMPK (complex) phosphorylates ULK1 (complex) (Saccharomyces cerevisiae)


name: 2-heptyl-4(1H)-quinolone + CO2 + CoA + H2O => (2-aminobenzoyl)acetate + H(+) + octanoyl-CoA


name: 2-oxoglutarate(in) + glutarate(out) => 2-oxoglutarate(out) + glutarate(in)


name: Cleavage of Intronless Pre-mRNA at 3'-end (Gallus gallus)


name: 5-hydroxymethyl-dUMP + H2O <=> 2-deoxy-D-ribose 5-phosphate + 5-hydroxymethyluracil


name: E2F6 forms the PRC1L4 complex (Homo sapiens)


name: USP21 deubiquitinates RIPK1,DDX58 (Homo sapiens)


name: 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA + H2O => 5-methylaminomethyl-2-selenouridine(34) in tRNA + phosphate


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + phosphate => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + NH4(+)


name: Phosphorylation of GAB2 by SYK/FYN (Homo sapiens)


name: Potassium voltage-gated channels close in reponse to PKA (Homo sapiens)


name: photoreceptor cyclic-nucleotide phosphodiesterase activity


name: SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 (Sus scrofa)


name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor


name: Myristoylated NPHP3 translocates into the ciliary membrane (Homo sapiens)


name: glutathione amide disulfide + 2 H2O => 2 glutathione amide + H2O2


name: H2O + sn-glycero-3-phospho-1D-myo-inositol => 1D-myo-inositol 1-phosphate + glycerol + H(+)


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Drosophila melanogaster)


name: 3-(4-aminophenyl)pyruvate + L-glutamate => 2-oxoglutarate + 4-amino-L-phenylalanine


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Sus scrofa)


name: Recruitment of ITK to SLP-76 (Sus scrofa)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + H(+) + NADH


name: mitochondrial large ribosomal subunit binding


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Homo sapiens)


name: 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate => 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O


name: SMURF1/2 ubiquitinates PTCH1 (Homo sapiens)


name: ATP + erythritol <=> ADP + D-erythritol 4-phosphate + H(+)


name: L-methionyl-[protein] + S-adenosyl-L-methionine => S-adenosyl-L-homocysteine + S-methyl-L-methionyl-[protein]


name: Activated FGFR1 phosphorylates FRS2 (Bos taurus)


name: 3-oxosphinganine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoyl-3-oxosphinganine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine


name: APEH hydrolyses NAc-Ser-protein (Sus scrofa)


name: KCNK dimers transport K+ from cytosol to extracellular region (Gallus gallus)


name: Viral Spike Binds to ACE2 on Uninfected Cell (Homo sapiens)


name: Formation of the CTF18 complex (Caenorhabditis elegans)


name: L-arginine transmembrane transporter activity


name: 1D-myo-inositol 3-phosphate + H2O => myo-inositol + phosphate


name: SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)


name: p75NTR and RHOA-GDI interact (Mus musculus)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Sus scrofa)


name: α1-antagonists bind ADRA1A,B,D (Xenopus tropicalis)


name: 2 7-demethylsiderin + NADPH + O2 <=> desertorin A + 2 H2O + NADP(+)


name: (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+) => catechol + H(+) + NADPH


name: ATP + L-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate


name: hydrogencarbonate(in) + Na(+)(in) => hydrogencarbonate(out) + Na(+)(out)


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Xenopus tropicalis)


name: (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 <=> (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + (3R)-all-trans-3-hydroxyretinal


name: (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMNH2 + O2 => benzaldehyde + FMN + H(+) + H2O + N-acetyl-S-hydroxy-L-cysteine


name: Addition of GlcNAc to the glycan on the A arm (Danio rerio)


name: RAC1,RAC2,RHOG activate PI3K (Gallus gallus)


name: Granzyme-B activates BID by cleavage (Rattus norvegicus)


name: ATP + thiamine => ADP + H(+) + thiamine phosphate


name: a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Phosphorylation and activation of PLCG (Bos taurus)


name: C20 sphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (4R)-hydroxyeicosasphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: dihydro-ML-236C carboxylate + O2 + reduced [NADPH--hemoprotein reductase] <=> 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PLK1 phosphorylates FIRMM at S744 (Homo sapiens)


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Mus musculus)


name: citrate(out) + succinate(in) <=> citrate(in) + succinate(out)


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Xenopus tropicalis)


name: Recruitment of Dna2 endonuclease (Canis familiaris)


name: 3-oxododecanoyl-[ACP] + CO2 + CoA => decanoyl-CoA + H(+) + malonyl-[ACP]


name: Coumarin is 7-hydroxylated by CYP2A6 (Dictyostelium discoideum)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + ethanolamine


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Gallus gallus)


name: 12-phosphooxy-(9Z)-octadecenoate + H2O => 12-hydroxy-(9Z)-octadecenoate + phosphate


name: ISGylation of PKR (Caenorhabditis elegans)


name: MAP3K8 is phosphorylated (Xenopus tropicalis)


name: a 3-O-beta-D-glucosyl-beta-D-glucuronoside + phosphate = a beta-D-glucuronoside + alpha-D-glucose 1-phosphate


name: 2-oxoglutarate + decyl sulfate + O2 = CO2 + decanal + H(+) + succinate + sulfate


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Dictyostelium discoideum)


name: SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Drosophila melanogaster)


name: NLK translocates to nucleus (Saccharomyces cerevisiae)


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Dictyostelium discoideum)


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Schizosaccharomyces pombe)


name: SLC43A1 (LAT3)-mediated uptake of large neutral amino acids (Mus musculus)


name: 6-deoxy-6-sulfo-D-gluconate + H(+) => 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H2O


name: SLCO4C1 mediates the transport of digoxin (Mus musculus)


name: butyl 3-(methylsulfanyl)propanoate + CoA => 3-(methylsulfanyl)propanoyl-CoA + butan-1-ol


name: PDSS1,2 ligates FPP to IPPP (Plasmodium falciparum)


name: Activation of Potassium transport channels (Sus scrofa)


name: modified amino acid transmembrane transporter activity


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Rattus norvegicus)


name: MET phosphorylates SHC1-2 (Homo sapiens)


name: apo-[aequorin] + coelenterazine => apo-[aequorin]--coelenterazine


name: glycochenodeoxycholate + NADP(+) = 7-oxoglycolithocholate + H(+) + NADPH


name: di-trans,poly-cis-dolichol + hexadecanoyl-CoA <=> a dolichyl hexadecanoate + CoA


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Homo sapiens)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Xenopus tropicalis)


name: CO2 + 2 H2O + harderoheme III => Fe-coproporphyrin III + H(+) + H2O2


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base <=> a diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base


name: NAD(+) + pyridoxine => H(+) + NADH + pyridoxal


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Sus scrofa)


name: a hydroperoxide + 2 glutathione => an alcohol + glutathione disulfide + H2O


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Homo sapiens)


name: Thyrotropin-releasing hormone receptor binds thyrotropin (Mus musculus)


name: ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Plasmodium falciparum)


name: Defective TLR3 does not bind viral dsRNA (Homo sapiens)


name: Cytoslic carboxylases translocate to mitochondrial matrix (Bos taurus)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 => (6R)-L-erythro-6,7-dihydrobiopterin + H2O + L-tyrosine


name: dodecan-1-ol + NADP(+) = dodecanal + H(+) + NADPH


name: eicosanoyl-CoA + O2 = (2E)-eicosenoyl-CoA + H2O2


name: H2O + sphing-4-enine 1-phosphate <=> phosphate + sphing-4-enine


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Canis familiaris)


name: Transport of MHC II:Ii complex along Golgi to TGN (Rattus norvegicus)


name: acetylpyruvate + H2O = acetate + H(+) + pyruvate


name: Disassociation and translocation of STATs to the nucleus (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + a 1-acyl-sn-glycero-3-phosphoethanolamine + H(+) => 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O


name: 5-dehydro-D-gluconate + H(+) + NADPH => D-gluconate + NADP(+)


name: GNRHR binds GNRHR peptide antagonists (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IKBIP binds IKBKB and CHUK (Homo sapiens)


name: CRLF1:IL27 translocates to the extracellular region (Canis familiaris)


name: a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: AGK:Mg2+ phosphorylates MAG, DAG (Rattus norvegicus)


name: Docking of the TAP:EJC Complex with the NPC (Homo sapiens)


name: p300 acetylates RELA subunit (Canis familiaris)


name: acetyl-CoA + alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate => alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CoA


name: H(+) + S-adenosyl-L-homocysteine + spheroidene => demethylspheroidene + S-adenosyl-L-methionine


name: NO binds to Guanylate Cyclase (Homo sapiens)


name: rifamycin SV hemiaminal => H(+) + rifamycin SV ortho-naphthoquinone carboxamide


name: (3S)-3-hydroxy-L-asparaginyl-[hypoxia-inducible factor alpha subunit] + CO2 + succinate => 2-oxoglutarate + L-asparaginyl-[hypoxia-inducible factor alpha subunit] + O2


name: a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + H2O + NAD(+) => a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + O2


name: D-tyrosyl-tRNA(Tyr) + H2O = D-tyrosine + tRNA(Tyr)


name: Nephrin binds NCK (Caenorhabditis elegans)


name: Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)


name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 (Rattus norvegicus)


name: 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-octadecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 (Homo sapiens)


name: H(+) + H2O + isoguanine <=> NH4(+) + xanthine


name: TOPORS SUMOylates SIN3A with SUMO1 (Dictyostelium discoideum)


name: 2-deoxy-alpha-D-ribose 1-phosphate + thymine => phosphate + thymidine


name: luteolin + S-adenosyl-L-methionine => chrysoeriol + H(+) + S-adenosyl-L-homocysteine


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate <=> 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate


name: cAMP degradation by Phosphodiesterases (Xenopus tropicalis)


name: AJUBA binds centrosome-associated AURKA (Rattus norvegicus)


name: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-tyrosine = 2-aminoprop-2-enoate + phenol


name: 3beta-hydroxy-5-androstene-7,17-dione + H(+) + NADPH <=> 3beta,7beta-dihydroxyandrost-5-en-17-one + NADP(+)


name: H2O + N(2)-(4-aminobutanoyl)-L-arginine = 4-aminobutanoate + L-arginine


name: ATP + H(+) + IC-asc-C7 => diphosphate + IC-asc-C7-AMP


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Homo sapiens)


name: DAXX binds Ub-MDM2 and USP7 (Mus musculus)


name: Acireductone is oxidized to MOB (Drosophila melanogaster)


name: ABCF1 binds EIF2 (Drosophila melanogaster)


name: USP17L2 deubiquitinates RCE1 (Sus scrofa)


name: a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine => a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]


name: dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine = dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + H(+) + S-adenosyl-L-homocysteine


name: SLC25A11 exchanges 2-OG and MAL (Bos taurus)


name: glucoside transmembrane transporter activity


name: Translocation of RIAM to plasma membrane (Canis familiaris)


name: MASTL phosphorylates ENSA (Canis familiaris)


name: ULK1 Translocates to the mitochondria (Sus scrofa)


name: glyoxylate + NH4(+) => 2-iminoacetate + H2O


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Sus scrofa)


name: ANKLE2 binds PP2A (Drosophila melanogaster)


name: MAP1LC3B binds KEAP1 and SQSTM1 (Sus scrofa)


name: H2O + L-threonyl-tRNA(Ile) = L-threonine + tRNA(Ile)


name: an R-cob(III)alamin + apo-[alkylcobalamin reductase] + glutathione <=> an S-substituted glutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+)


name: Unknown nuclease cleaves pre-piRNA in ASZ1:DDX4:MOV10L1:6xMeR-PIWIL2:pre-piRNA:TDRD1:TDRD12 (Homo sapiens)


name: IL12RB1:TYK2 binds IL12RB2:JAK2 (Canis familiaris)


name: glycocholate + NAD(+) => 7-oxo-glycodeoxycholate + H(+) + NADH


name: 19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: 3-methyl fatty acid + ATP + CoA = a 3-methyl fatty acyl-CoA + AMP + diphosphate


name: (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 <=> 3-[(E)-2-isocyanovinyl]indole + 2 CO2 + H2O + succinate


name: (2E,6E)-farnesyl diphosphate => (+)-(E)-beta-caryophyllene + diphosphate


name: apulose + ATP => ADP + apulose 4-phosphate + H(+)


name: SALL4 recruits NuRD to PTEN gene (Gallus gallus)


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O => ADP-alpha-D-ribose 1''-phosphate + H(+)


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Caenorhabditis elegans)


name: LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (Homo sapiens)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Drosophila melanogaster)


name: Phosphorylation of p-KIT on Y900 by Src kinases (Bos taurus)


name: dADP(out) + H(+)(out) + phosphate(in) = dADP(in) + H(+)(in) + phosphate(out)


name: ADP + gamma-L-glutamyl-L-glutamyl-[protein] + H(+) + phosphate => ATP + L-glutamate + L-glutamyl-[protein]


name: glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Caenorhabditis elegans)


name: G6PC2 hydrolyzes G6P to form Glc and Pi (islet) (Homo sapiens)


name: (S)-malate + ubiquinone-8 <=> oxaloacetate + ubiquinol-8


name: CYP3A4 binds CYP3A4 inhibitors (Canis familiaris)


name: 2'-deamino-2'-hydroxyneamine + 2-oxoglutarate = 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate


name: Formation of RAD52 heptameric ring structure complexes (Dictyostelium discoideum)


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Sus scrofa)


name: RIPK3 binds p-S9-PRKN (Rattus norvegicus)


name: Caspase-1 active tetramer formation (Mus musculus)


name: Retromer recycles WLS to the Golgi (Dictyostelium discoideum)


name: D-ribulose 5-phosphate + L-tyrosine = (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + formaldehyde + H(+) + H2O + hydroxyacetone + phosphate


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Drosophila melanogaster)


name: SLC6A6-mediated uptake of taurine and beta-alanine (Sus scrofa)


name: ZIP6 and ZIP14 mediate zinc influx into cells (Danio rerio)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Rattus norvegicus)


name: a plastoquinone + H2O + L-arginine = 5-guanidino-2-oxopentanoate + a plastoquinol + NH4(+)


name: a 2'-deoxyribonucleoside 3'-phosphate + H2O <=> a 2'-deoxyribonucleoside + phosphate


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Danio rerio)


name: Canonical WNT signaling through the atypical receptor RYK (Drosophila melanogaster)


name: UIMC1 and FAM175A bind DNA DSBs (Sus scrofa)


name: HDAC10 deacetylates histone (Canis familiaris)


name: Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Xenopus tropicalis)


name: RND2 binds effectors (Rattus norvegicus)


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Danio rerio)