name: chromate transmembrane transporter activity


name: RHOC binds effectors at the plasma membrane (Gallus gallus)


name: 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Rattus norvegicus)


name: nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical  HDL + chylomicron (Mus musculus)


name: aclacinomycin T + H2O <=> 15-demethylaclacinomycin T + methanol


name: A + dihydroserpentine = AH2 + serpentine


name: NUDT12 hydrolyses NADH to NMNH (Bos taurus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA => 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Homo sapiens)


name: miR-17 microRNA binds CNOT6L mRNA (Homo sapiens)


name: 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+) => a 1-acylglycerone 3-phosphate + a long chain fatty alcohol


name: HuR binds the CRM1 nuclear export machinery (Sus scrofa)


name: TCF:Beta-catenin binds SOX proteins (Drosophila melanogaster)


name: Metallochaperone inserts Cu2+ into MT-CO1 (Homo sapiens)


name: 1-chloro-3-nitrobenzene + NADH + O2 => 4-chlorocatechol + NAD(+) + nitrite


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Bos taurus)


name: E2F1 binds PMAIP1 (NOXA) promoter (Homo sapiens)


name: an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O <=> an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Xenopus tropicalis)


name: acetyl-CoA + 2 AH2 + 9 H(+) + malate + 6 malonyl-CoA + 5 NADPH + 2 S-adenosyl-L-methionine => 2 A + 6 CO2 + 7 CoA + 6 H2O + 5 NADP(+) + 2 S-adenosyl-L-homocysteine + trihazone A


name: activated chicken MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)


name: 2-oxoglutarate + L-2,4-diaminobutanoate = L-aspartate 4-semialdehyde + L-glutamate


name: (E)-2-methylpropanal oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-valine


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Mus musculus)


name: Activation of Rac1 by VAV2 (Mus musculus)


name: Active ALK phosphorylates IRS1 (Mus musculus)


name: SETD8 monomethylates histone H4 (Danio rerio)


name: PVR:PVRL3 trans heterodimer interaction (Danio rerio)


name: (S)-2-hydroxypropyl-coenzyme M => (S)-1,2-epoxypropane + coenzyme M


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Mus musculus)


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Caenorhabditis elegans)


name: HINT1 binds MITF-M (Caenorhabditis elegans)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Drosophila melanogaster)


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Saccharomyces cerevisiae)


name: creatinine(in) + H(+)(out) => creatinine(out) + H(+)(in)


name: GST trimers transfer GS from GSH to luminal substrates (Rattus norvegicus)


name: alpha-D-glucose 1-phosphate + CTP + H(+) => CDP-D-glucose + diphosphate


name: 5-oxopentanoate + H2O + NADP(+) = glutarate + 2 H(+) + NADPH


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Canis familiaris)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Xenopus tropicalis)


name: SUMOylation of TOPORS with SUMO1 (Dictyostelium discoideum)


name: 7,8-dihydropteroate + diphosphate => (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate


name: HCO3- transport through ion channel (Danio rerio)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 6beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glutarate(out) + 3 Na(+)(out) = glutarate(in) + 3 Na(+)(in)


name: ATP + coproporphyrin III(in) + H2O <=> ADP + coproporphyrin III(out) + H(+) + phosphate


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + H2O => 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + NH4(+)


name: SORD tetramer oxidizes xylitol to D-xylulose (Schizosaccharomyces pombe)


name: 4-aminobutanoate(out) + L-glutamate(in) => 4-aminobutanoate(in) + L-glutamate(out)


name: PTPN6 dephosphorylates JAK3 (Homo sapiens)


name: RNA polymerase II CTD heptapeptide repeat P6 isomerase activity


name: ATP + D-glucose => ADP + D-glucose 6-phosphate + H(+)


name: LINC01139 promotes phosphorylation of HIF1A by PTK6 (Bos taurus)


name: SLC25A1 exchanges CIT and MAL (Sus scrofa)


name: ERBB3 binds RNF41 ubiquitin ligase (Rattus norvegicus)


name: (2S)-2-acetamido-4-aminobutanoate => H2O + L-ectoine


name: 2-exo-hydroxy-1,8-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 1,8-cineole + O2 + reduced [NADPH--hemoprotein reductase]


name: indole-3-pyruvate imine dimer => CO2 + NH4(+) + protodeoxyviolaceinate


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Dictyostelium discoideum)


name: 2,3,5,6-tetrachlorohydroquinone + H2O + NADP(+) => 2,3,5,6-tetrachlorophenol + NADPH + O2


name: EP3 receptor can bind PGE2 (Homo sapiens)


name: Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen (Canis familiaris)


name: SLC9B2 exchanges Na+ for H+ (Bos taurus)


name: The ABCC family mediates organic anion transport (Dictyostelium discoideum)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Saccharomyces cerevisiae)


name: MRN complex binds shortened telomeres (Mus musculus)


name: a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + 2 S-adenosyl-L-homocysteine => a 5'-end 5'-phospho-ribonucleoside-RNA + 2 S-adenosyl-L-methionine


name: 7-carboxymellein + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => 7-methylmellein + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: 7-oxopregnenolone + H(+) + NADPH = 7beta-hydroxypregnenolone + NADP(+)


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Bos taurus)


name: (R)-salsolinol + S-adenosyl-L-methionine => H(+) + N-methyl-(R)-salsolinol + S-adenosyl-L-homocysteine


name: agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O = 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate


name: (3R)-3-hydroxy-2,3-dihydrotabersonine + A => (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + AH2


name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex (Rattus norvegicus)


name: Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Gallus gallus)


name: PDCL promotes G-protein beta 5 folding (Xenopus tropicalis)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Xenopus tropicalis)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) <=> 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH


name: HIPK2 phosphorylates RUNX1 (Caenorhabditis elegans)


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Canis familiaris)


name: eIF3 and eIF1A bind to the 40S subunit (Dictyostelium discoideum)


name: O2 + reduced [NADPH--hemoprotein reductase] + trans-5-O-(4-coumaroyl)-D-quinate <=> 5-O-[(E)-caffeoyl]-D-quinate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GSDMD oligomerizes into arc-, slit-shaped structures (Rattus norvegicus)


name: a fatty acid + a monoacylglycerol + H(+) => a 1,2-diacylglycerol + H2O


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Bos taurus)


name: all-trans-retinyl hexadecanoate + H2O => 11-cis-retinol + H(+) + hexadecanoate


name: p-STAT1dimer:KPNA1 binds KPNB1 (Rattus norvegicus)


name: 3xPPCDC:3FMN decarboxylates PPC (Dictyostelium discoideum)


name: ATP + creatine <=> ADP + H(+) + N-phosphocreatine


name: Kinesin-7 is a dimer (Rattus norvegicus)


name: linalool + O2 + reduced [NADPH--hemoprotein reductase] <=> (6E)-8-hydroxylinalool + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + O-acyl-(R)-carnitine <=> (R)-carnitine + a fatty acid + H(+)


name: SUMOylation of TOP1 with SUMO1 (Schizosaccharomyces pombe)


name: all-trans-3,4-didehydroretinol + NAD(+) = all-trans-3,4-didehydroretinal + H(+) + NADH


name: cAMP induces dissociation of inactive PKA tetramers (Homo sapiens)


name: 2-acyl LPC is acylated to PC by LPCAT (Sus scrofa)


name: IL9 binds IL9R:JAK1 and IL2RG:JAK3 (Sus scrofa)


name: 2 a ubiquinol + phenylglyoxylyl-CoA => 2 a ubiquinone + H2O + phenylacetyl-CoA


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate <=> colnelenate + H2O


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Canis familiaris)


name: 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 3 AH2 + CO2 + H(+) => 3 A + FMN + H2O + L-glutamate + O2


name: 2 methanethiol + NAD(+) = dimethyl disulfide + H(+) + NADH


name: S-adenosyl-L-methionine + scutellarein 4'-methyl ether = ladanein + S-adenosyl-L-homocysteine


name: RvD1-6 translocate from cytosol to extracellular region (Homo sapiens)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Sus scrofa)


name: GLYCTK phosphorylates DGA to 3PDGA (Homo sapiens)


name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Xenopus tropicalis)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Caenorhabditis elegans)


name: hydroxymethylbilane = H2O + uroporphyrinogen III


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Bos taurus)


name: H(+) + IDP + phosphoenolpyruvate => ITP + pyruvate


name: 2 AH2 + 2 archaetidylglycerol + 4 S-adenosyl-L-methionine = 4 5'-deoxyadenosine + 2 A + glycerol dibiphytanyl glycerol tetraether glycerophospholipid + 4 H(+) + 4 L-methionine


name: 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] => 24,25-dihydrolanosterol + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin]


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Dictyostelium discoideum)


name: a carotenoid psi-end group => a carotenoid beta-end derivative


name: 16S rRNA pseudouridine(516) synthase activity


name: hydroperoxy icosatetraenoate isomerase activity


name: MARK3 phosphorylates KSR1 (Mus musculus)


name: H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphate => N-acyl-15-methylhexadecasphing-4-enine + phosphate


name: CYP19A1 binds Aromatase inhibitors (Drosophila melanogaster)


name: erythronolide B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 6-deoxyerythronolide B + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: NADPH + sanguinarine => dihydrosanguinarine + NADP(+)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Rattus norvegicus)


name: KCNH2:KCNE transport K+ from cytosol to extracellular region (Sus scrofa)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Rattus norvegicus)


name: 6-phospho-2-dehydro-D-gluconate + ADP + H(+) => 2-dehydro-D-gluconate + ATP


name: MAGED1 binds NPAS4 (Drosophila melanogaster)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O => a 5'-end phospho (purine-ribonucleoside) in mRNA + 2 H(+) + N(7)-methyl-GDP


name: GABRR pentamers:GABA transports extracellular Cl- to cytosol (Gallus gallus)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 19-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Defective SGSH does not hydrolyse Heparan sulfate chain(2) (Homo sapiens)


name: (E,E)-piperoyl-CoA + pyrrolidine = CoA + H(+) + piperyline


name: Pro-beta-NGF and mature beta-NGF are secreted (Sus scrofa)


name: glycerol + H(+) + octanoate => 1-octanoylglycerol + H2O


name: ARL2:GTP binds ARL2BP (Xenopus tropicalis)


name: SLC46A1 transports FOLA from extracellular region to cytosol (Canis familiaris)


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Homo sapiens)


name: 3-hydroxy-L-kynurenine + pyruvate <=> H2O + L-alanine + xanthurenate


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Bos taurus)


name: Binding of ADAR1 homodimer to dsRNA duplex (Sus scrofa)


name: (indol-3-yl)acetyl-AMP + CoA <=> (indol-3-yl)acetyl-CoA + AMP + H(+)


name: beta-alanine(out) + chloride(out) + 2 Na(+)(out) = beta-alanine(in) + chloride(in) + 2 Na(+)(in)


name: 8-O-methyldihydrosterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => aflatoxin B2 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase]


name: a fatty acyl-CoA + phytol = a fatty acid phytyl ester + CoA


name: IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Bos taurus)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Mus musculus)


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Mus musculus)


name: pS181-S-Farn-Me KRAS4B binds BCL2L1 (Sus scrofa)


name: CALCA(83-119) binds CALCR (Mus musculus)


name: CASP9 is phosphorylated at T412 (Danio rerio)


name: Ubiquitinated Orc1 is degraded by the proteasome (Schizosaccharomyces pombe)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Danio rerio)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Rattus norvegicus)


name: XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Mus musculus)


name: IKK-beta is recruited (Rattus norvegicus)


name: 19-hydroxytestosterone + O2 + reduced [NADPH--hemoprotein reductase] => 19-oxotestosterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 5,10-methylenetetrahydromethanopterin + NADP(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Plasmodium falciparum)


name: USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Saccharomyces cerevisiae)


name: (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate = (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O


name: VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Rattus norvegicus)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Xenopus tropicalis)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Caenorhabditis elegans)


name: MLH1 variants-defective DNA mismatch repair (Homo sapiens)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: H2O + kynuramine + O2 <=> 3-(2-aminophenyl)-3-oxopropanal + H2O2 + NH4(+)


name: Binding and activation of MAP Kinase (Homo sapiens)


name: RUNX1 binds to TNFRSF18 (GITR) gene promoter and intron 1 (Homo sapiens)


name: DKC1 binds SHQ1 (Saccharomyces cerevisiae)


name: Neurotensin receptors can bind neurotensins (Danio rerio)


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Dictyostelium discoideum)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Bos taurus)


name: The anterograde IFT train dissociates (Sus scrofa)


name: 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin] => (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin]


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Xenopus tropicalis)


name: LTA4 is hydolysed to LTB4 by LTA4H (Drosophila melanogaster)


name: TIRAP binds PIP2-rich regions in the plasma membrane (Mus musculus)


name: HOXB2 gene is transcribed (Homo sapiens)


name: protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Mus musculus)


name: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol (Dictyostelium discoideum)


name: ATP + H2O + hydrogenselenide = AMP + 2 H(+) + phosphate + selenophosphate


name: (9Z)-octadecenoyl-CoA + 1-decanoylglycerol => 1-decanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: Oligomerization  of BAK at the mitochondrial membrane (Sus scrofa)


name: H2O + propanoyl-CoA <=> adenosine 3',5'-bisphosphate + 2 H(+) + propanoyl-4'-phosphopantetheine


name: 12-octadecanoyloxy-octadecanoate + H2O <=> 12-hydroxyoctadecanoate + H(+) + octadecanoate


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Bos taurus)


name: 1-O-alkyl-2-acyl-sn-glycerol + an acyl-CoA <=> 1-O-alkyl-2,3-diacyl-sn-glycerol + CoA


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Xenopus tropicalis)


name: Dephosphorylation of TYK2 by PTP1B (Homo sapiens)


name: FMNH2 + N-acetyl-S-methyl-L-cysteine + O2 = (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: Formation of eIF2:GDP:eIF2B intermediate (Schizosaccharomyces pombe)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Xenopus tropicalis)


name: 7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) => 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: 2-acyl LPS is acylated to PS by LPSAT (Schizosaccharomyces pombe)


name: trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP


name: Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Canis familiaris)


name: 2,5-didehydro-D-gluconate + AH2 => 2-dehydro-D-gluconate + A


name: 2-oxoglutarate + O2 + prekainate = CO2 + H2O + kainate + succinate


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Mus musculus)


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Rattus norvegicus)


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Canis familiaris)


name: N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose <=> beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + H(+) + UDP


name: Phosphorylation of MDM4 by CHEK2 (Canis familiaris)


name: (2E)-geranyl diphosphate => beta-myrcene + diphosphate


name: D-xylose(in) + H(+)(in) = D-xylose(out) + H(+)(out)


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Rattus norvegicus)


name: NFKB1:RELA translocates from the cytosol to the nucleus (Canis familiaris)


name: succinate(in) + urate(out) = succinate(out) + urate(in)


name: CTP(out) + dCMP(in) => CTP(in) + dCMP(out)


name: Autocatalytic phosphorylation of FGFR1c (Drosophila melanogaster)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Canis familiaris)


name: Interaction of E3 ligase with ISG15:E2 complex (Homo sapiens)


name: 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H(+) = deacetylpyripyropene E


name: polyol transmembrane transporter activity


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Homo sapiens)


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Dictyostelium discoideum)


name: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = 5alpha-cholestane-3beta,5,6beta-triol


name: an omega-oxo fatty acid + H2O + NAD(+) => a dicarboxylate + 2 H(+) + NADH


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Mus musculus)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Homo sapiens)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Danio rerio)


name: ATP + H2O + N-acetyl-L-aspartate(in) <=> ADP + H(+) + N-acetyl-L-aspartate(out) + phosphate


name: Resynthesis of excised residue by POLB (Bos taurus)


name: AKT phosphorylates FOXO transcription factors (Danio rerio)


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b (d18:1(4E)) + CMP + H(+)


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + (E)-caffeoyl-CoA = (R)-rosmarinate + CoA


name: Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 (Danio rerio)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Drosophila melanogaster)


name: USP33 deubiquitinates ROBO1 (Mus musculus)


name: Intrinsic nucleotide exchange on RAS (Rattus norvegicus)


name: N(pros)-phospho-L-histidyl-[protein](out) + sucrose = L-histidyl-[protein] + sucrose 6(G)-phosphate(in)


name: 2 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) <=> 2 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: 2-oxoglutarate + ATP + hydrogencarbonate = (S)-oxalosuccinate + ADP + H(+) + phosphate


name: ATP + L-pyrrolysine + tRNA(Pyl) <=> AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl)


name: Activated FGFR2 binds FRS2 (Homo sapiens)


name: FGAM + ATP => AIR + ADP + Pi (Xenopus tropicalis)


name: Ferriheme is transferred from Methemoglobin to Hemopexin (Mus musculus)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 <=> (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2


name: 7-carboxy-7-deazaguanine + ATP + NH4(+) <=> 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate


name: IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Dictyostelium discoideum)


name: (8Z,11Z,14Z)-eicosatrienamide + H2O => (8Z,11Z,14Z)-eicosatrienoate + NH4(+)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Bos taurus)


name: PRKN ubiquitinates MOM substrates (Canis familiaris)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Homo sapiens)


name: Formation of alternative pathway C5 convertase (Homo sapiens)


name: (R)-4'-phosphopantetheine + H2O = (R)-pantetheine + phosphate


name: 6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine + H2O = N-acetyl-D-glucosamine + N-acetyl-D-muramate 6-phosphate


name: (8Z,11Z,14Z)-eicosatrienoate + 2 O2 = prostaglandin G1


name: Anthrax lef cleaves target cell MAP2K1 (MEK1) (Homo sapiens)


name: diphosphate + fumigaclavine C => dimethylallyl diphosphate + fumigaclavine A


name: H(+) + N-acyl-15-methylhexadecasphinganine + NADPH + O2 <=> H2O + N-acyl-4-hydroxy-15-methylhexadecasphinganine + NADP(+)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminoadipate => 2-oxoadipate + L-kynurenine


name: a carboxylate + L-homoserine lactone => an N-acyl-L-homoserine lactone + H2O


name: Kinesins move along microtubules consuming ATP (Homo sapiens)


name: (8R,9R)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate => (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O


name: Gi activation by P2Y purinoceptor 12 (Xenopus tropicalis)


name: (6R)-10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinose <=> (6S)-5,6,7,8-tetrahydrofolate + H(+) + UDP-4-deoxy-4-formamido-beta-L-arabinose


name: RHOG GEFs activate RHOG (Xenopus tropicalis)


name: 1-O-(alk-1-enyl)-sn-glycero-3-phosphate + H2O => 1-O-(alk-1-enyl)-sn-glycerol + phosphate


name: KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 (Schizosaccharomyces pombe)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (3S,6E)-nerolidol + diphosphate


name: Acitretin binds to RAR:RXR (Canis familiaris)


name: AH2 + prostaglandin G3 <=> A + H2O + prostaglandin H3


name: Exocytosis of platelet alpha granule contents (Gallus gallus)


name: putrescine + spermidine => propane-1,3-diamine + sym-homospermidine


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Sus scrofa)


name: adenosine 3',5'-bisphosphate + firefly L-sulfoluciferin + H(+) => 3'-phosphoadenylyl sulfate + firefly L-luciferin


name: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 5,10-methylenetetrahydromethanopterin + H2O => 5,6,7,8-tetrahydromethanopterin + formaldehyde


name: The Ligand:GPCR:Gi complex dissociates (Bos taurus)


name: Late core complex dimerizes (Homo sapiens)


name: DNMT3B:DNMT3L methylates cytosine in DNA (Homo sapiens)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Homo sapiens)


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Gallus gallus)


name: diphthamide-[translation elongation factor 2] + NAD(+) <=> H(+) + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] + nicotinamide


name: Extracellular BTD hydrolyses BCTN (Rattus norvegicus)


name: a sphingomyelin + H2O = an N-acylsphing-4-enine 1-phosphate + choline + H(+)


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Mus musculus)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Bos taurus)


name: RAC2 binds effectors at the mitochondrial outer membrane (Rattus norvegicus)


name: 1-O-alkylglycerone 3-phosphate + H(+) + NADPH = 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O => a 1-acyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: Caspase-mediated cleavage of MASK (Bos taurus)


name: an octanoate ester + H2O = an aliphatic alcohol + H(+) + octanoate


name: beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose => beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP + H(+)


name: alpha-D-mannose 1-phosphate <=> D-mannose 6-phosphate


name: D-apiitol + NAD(+) = aldehydo-D-apiose + H(+) + NADH


name: 9S,10-epoxy-(10,12Z)-octadecadienoate + H(+) + L-aspartyl-[protein] => 9-O-10-oxo-(12Z)-octadecenoate L-aspartatyl ester-[protein]


name: acetyl-CoA + N-terminal L-methionyl-L-lysyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein]


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Danio rerio)


name: 2 fonsecin B + H(+) + NADPH + O2 = bifonsecin B + 2 H2O + NADP(+)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Homo sapiens)


name: RHOU binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: 2 L-threonine => H2O + L-threonyl-L-threonine


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Xenopus tropicalis)


name: 4-hydroxy-3-all-trans-heptaprenylbenzoate + H(+) <=> 2-all-trans-heptaprenylphenol + CO2


name: UGTs glucuronate APAP to APAP-GlcA (Sus scrofa)


name: eNOS synthesizes NO (Caenorhabditis elegans)


name: CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Drosophila melanogaster)


name: p-4Y-SIRPA:CD47 binds PTPN6,PTPN11 (Homo sapiens)


name: (E)-sinapyl alcohol + NADP(+) = (E)-sinapaldehyde + H(+) + NADPH


name: FMNH2 + N-methylnicotinate + O2 <=> (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+)


name: tRNA (adenine) methyltransferase activity


name: PANK2 phosphorylates PanK (Xenopus tropicalis)


name: H2O + methylglyoxal + NAD(+) <=> 2 H(+) + NADH + pyruvate


name: an N-acylsphinganine + H2O = a fatty acid + sphinganine


name: myricetin + UDP-beta-L-rhamnose <=> H(+) + myricetin 3-O-alpha-L-rhamnoside + UDP


name: Receptor FFAR1 binds free fatty acids (Bos taurus)


name: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate


name: (R)-prunasin + D-glucose => (R)-amygdalin + H2O


name: ADP + beta-alanyl-L-lysine + H(+) + phosphate => ATP + beta-alanine + L-lysine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine <=> 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: LONP1 degrades mitochondrial matrix proteins (Saccharomyces cerevisiae)


name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] (Mus musculus)


name: H2O + L-cysteinyl-tRNA(Cys) = H(+) + L-cysteine + tRNA(Cys)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Homo sapiens)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Danio rerio)


name: cyclic nucleotide-dependent protein kinase activity


name: biotinate sulfoxide + H(+) + NADH = biotin + H2O + NAD(+)


name: Formation of the SET1B complex (Drosophila melanogaster)


name: Relaxin receptor 1 binds relaxin 2 and 3 (Bos taurus)


name: Multi-ubiquitination of APOBEC3G (Homo sapiens)


name: SLC35D2 exchanges UDP-D-glucose for UMP (Caenorhabditis elegans)


name: CoA + H(+) + N-terminal N-hexadecanoyl-L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester => hexadecanoyl-CoA + N-terminal L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester


name: PGH2 is isomerised to PGE2 by PTGES (Canis familiaris)


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Sus scrofa)


name: LC3:ATG7 dimer binds ATG3 (Drosophila melanogaster)


name: GDP is exchanged for GTP on DRheb (Drosophila melanogaster)


name: SUMOylation of Histone H4 with SUMO1 (Saccharomyces cerevisiae)


name: NOTCH1 PEST domain mutants bind DLL1  (Homo sapiens)


name: acetyl-CoA + an S-substituted L-cysteine => an N-acetyl-L-cysteine-S-conjugate + CoA + H(+)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+) => (R)-glycerate + ADP-alpha-D-glucose


name: plasmodiophorol C => H2O + plasmodiophorol B


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O <=> a 5'-end phospho (purine-ribonucleoside) in mRNA + 2 H(+) + N(7)-methyl-GDP


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Mus musculus)


name: (E)-but-1-en-1-SO-peroxol = (Z)-butanethial oxide


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Drosophila melanogaster)


name: 3-oxooctacosanyol-CoA + H(+) + NADPH <=> (3R)-hydroxyoctacosanoyl-CoA + NADP(+)


name: an (S)-2-haloacid + H2O <=> a (2R)-2-hydroxycarboxylate + a halide anion + H(+)


name: Formation of caspase-1 p10/p20 dimer (Homo sapiens)


name: D-allose 6-phosphate = D-allulose 6-phosphate


name: a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: type 5 metabotropic glutamate receptor binding


name: 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+) => an inositol-1-phosphoceramide + H2O


name: chlorohydroquinone + O2 => 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H(+)


name: p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Drosophila melanogaster)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Homo sapiens)


name: Hydrolysis of PIP3 to PI(3,4)P2 (Sus scrofa)


name: 2-oxoglutarate + butyl sulfate + O2 = butanal + CO2 + H(+) + succinate + sulfate


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Drosophila melanogaster)


name: adenosine(1408) in 16S rRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methyladenosine(1408) in 16S rRNA + S-adenosyl-L-homocysteine


name: corticosterone + NAD(+) <=> 11-dehydrocorticosterone + H(+) + NADH


name: di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate => (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate


name: CIT (citron kinase) binds activated RHOA, RHOB, RHOC and RAC1 (Homo sapiens)


name: RBX1:CUL3 dissociates from forming autophagosome (Dictyostelium discoideum)


name: (2E,6E)-farnesyl diphosphate = alpha-himachalene + diphosphate


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP


name: NEUROG3-dependent synthesis of NEUROD1 (Homo sapiens)


name: chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex (Bos taurus)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Caenorhabditis elegans)


name: ATP + GDP = AMP + guanosine 3',5'-bis(diphosphate)


name: D-glucose + strictosidine aglycone => 3alpha(S)-strictosidine + H2O


name: arginine + H2O => ornithine + urea [ARG1] (Rattus norvegicus)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Homo sapiens)


name: 32-oxoeburicol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 32-hydroxyeburicol + O2 + reduced [NADPH--hemoprotein reductase]


name: CDH11 canonical mRNA is translated into CDH11 canonical protein isoform (Homo sapiens)


name: Multiubiquitination of Nek2A (Bos taurus)


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-alpha-D-galactose = H(+) + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP


name: 3-oxoisoapionate 4-phosphate + H(+) => CO2 + L-erythrulose 1-phosphate


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Mus musculus)


name: 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine => 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate <=> 1,3-di-(9Z)-hexadecenoylglycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a (Bos taurus)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Danio rerio)


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Rattus norvegicus)


name: 5-dehydro-4-deoxy-D-glucarate + H(+) => 2,5-dioxopentanoate + CO2 + H2O


name: 10-formyldihydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 7,8-dihydrofolate


name: CO2 + phosphate + succinate + uridine-5'-aldehyde => 2-oxoglutarate + O2 + UMP


name: gamma-glutamyl hercynylcysteine sulfoxide synthase activity


name: pppA(2'-5')pG <=> 3',2'-cGAMP + diphosphate


name: MAF1 translocates to the nucleus (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O => a 1-acyl-sn-glycero-3-phosphate + a fatty acid + H(+)


name: NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: (R)-3-methyl-2-oxopentanoate + H2O2 + NH4(+) => D-isoleucine + H2O + O2


name: 2,6-dichlorohydroquinone + FADH2 + O2 => 2-chloro-6-hydroxy-1,4-benzoquinone + chloride + FAD + 2 H(+) + H2O


name: citrate(out) + fumarate(in) = citrate(in) + fumarate(out)


name: 3-iodo-L-tyrosine + iodide + NADP(+) = 3,5-diiodo-L-tyrosine + H(+) + NADPH


name: D-cellotriose + O2 => D-cellotriono-1,5-lactone + H2O2


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Canis familiaris)


name: GBF1 stimulates nucleotide exchange on ARF4 (Mus musculus)


name: Cargo Recognition And Sorting (Canis familiaris)


name: Association of procollagen type XIV (Rattus norvegicus)


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Caenorhabditis elegans)


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Sus scrofa)


name: ENPP7 hydrolyzes sphingomyelin (Caenorhabditis elegans)


name: Cytosolic PLK1 translocates to the nucleus (Gallus gallus)


name: cyclohexanone + H(+) + NADH + NH4(+) => cyclohexylamine + H2O + NAD(+)


name: (indol-3-yl)butanoate + ATP + L-glutamine <=> (indol-3-yl)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers (Homo sapiens)


name: (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + 2-oxoglutarate + AH2 + H(+) + O2 => (2S)-5,5-dimethylpiperidine-2-carboxylate + A + 2 CO2 + H2O + succinate


name: JAK1-mediated phosphorylation of RAF1 (Sus scrofa)


name: 3-oxoglycyrrhetinate + H(+) + NADPH => 3alpha-hydroxyglycyrrhetinate + NADP(+)


name: calcium-dependent protein kinase regulator activity


name: Kinesin-5 is a homotetramer (Rattus norvegicus)


name: OSM binds LIFR:JAKs,OSMR:JAKs (Mus musculus)


name: H2O + oxaloacetate = acetate + H(+) + oxalate


name: 3'-phosphoadenylyl sulfate + taurocholate <=> adenosine 3',5'-bisphosphate + H(+) + taurocholate 7-sulfate


name: TIMM23 SORT inserts proteins into inner membrane (Homo sapiens)


name: Glypican-1 (GPC1) binds SLIT2 (Bos taurus)


name: Interaction of Tie2 and Shc1 (Homo sapiens)


name: Dephosphorylation of AKT by PP2A (Mus musculus)


name: CDC14A,B bind MAPK6 (Schizosaccharomyces pombe)


name: (3Z)-phytochromobilin + 2 oxidized [2Fe-2S]-[ferredoxin] = biliverdin IXalpha + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 3-(all-trans-nonaprenyl)benzene-1,2-diol + H2O + NADP(+) => 2-all-trans-nonaprenylphenol + H(+) + NADPH + O2


name: Retinoic acid activates HOXD4 chromatin (Homo sapiens)


name: (S)-lactate(out) + Na(+)(out) = (S)-lactate(in) + Na(+)(in)


name: 3-oxochol-4-en-24-oyl-CoA + NAD(+) <=> 3-oxochol-4,6-dien-24-oyl-CoA + H(+) + NADH


name: 3-methylbutanoyl-CoA + S-adenosyl-L-methionine <=> CoA + H(+) + N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine


name: RNF41 binds neuregulin-activated ERBB3 (Rattus norvegicus)


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Schizosaccharomyces pombe)


name: (12R-hydroxy-9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA => (12R)-hydroxy-(9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphocholine


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Xenopus tropicalis)


name: ABCG4 may mediate cholesterol efflux (Saccharomyces cerevisiae)


name: Interaction of E3 with substrate and E2-Ub complex (Mus musculus)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Danio rerio)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Mus musculus)


name: Caspase-mediated cleavage of Acinus (Mus musculus)


name: Methylation of GMP-cap by RNA Methyltransferase (Drosophila melanogaster)


name: TXA2 is hydrolysed to TXB2 (Homo sapiens)


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Gallus gallus)


name: MARK3 phosphorylates KSR1 (Drosophila melanogaster)


name: CDK5 phosphorylates NTRK2 (Homo sapiens)


name: Re-integration of insulin receptor into plasma membrane (Xenopus tropicalis)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18] => acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18]


name: FNTB inhibitors bind FNTA:FNTB (Gallus gallus)


name: 5-methyl-CTP + H2O => 5-methyl-CMP + diphosphate + H(+)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Gallus gallus)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Mus musculus)


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Sus scrofa)


name: IRAK4-activated IRAK1 autophosphorylates (Homo sapiens)


name: (E)-caffeoyl-CoA + S-adenosyl-L-methionine <=> (E)-feruloyl-CoA + H(+) + S-adenosyl-L-homocysteine


name: hexadecanoyl-CoA + tetradecan-1-ol => CoA + tetradecanyl hexadecanoate


name: NEU2 hydrolyzes Neu5Ac from glycoconjugates (Sus scrofa)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Caenorhabditis elegans)


name: H2O + L-2-amino-4-chloropent-4-enoate <=> 2-oxopent-4-enoate + chloride + H(+) + NH4(+)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)


name: MEN1 binds MLL1 complex (Rattus norvegicus)


name: Factor IIa inhibitors (peptide) binds IIa (Homo sapiens)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: rifamycin SV hemiaminal <=> H(+) + rifamycin SV ortho-naphthoquinone carboxamide


name: (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: daunorubicin + H(+) + NADPH + O2 <=> doxorubicin + H2O + NADP(+)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Sus scrofa)


name: 12-epi-fischerindole U + 2-oxoglutarate + chloride + H(+) + O2 <=> 12-epi-fischerindole G + CO2 + H2O + succinate


name: 1-amino-1-deoxy-scyllo-inositol + ATP => 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + H(+)


name: 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one (Schizosaccharomyces pombe)


name: a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine


name: ERK1/2/5 activate RSK1/2/3 (Canis familiaris)


name: N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + O2 + reduced [NADPH--hemoprotein reductase] => 2-oxo-N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: all-trans-4-hydroxyretinol + H2O + 2 oxidized [adrenodoxin] => all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: atRAL can spontaneously react with PE to form NRPE (Homo sapiens)


name: acetyl-CoA + 10 AH2 + 2 H(+) + 7 malonyl-CoA + 5 S-adenosyl-L-methionine <=> 10 A + 7 CO2 + 8 CoA + dehydroprobetaenone I + 6 H2O + 5 S-adenosyl-L-homocysteine


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Schizosaccharomyces pombe)


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Mus musculus)


name: (+)-cis-trans-nepetalactol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 7-deoxyloganetate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a D-alpha-amino acid + acetyl-CoA = an N-acetyl-D-amino acid + CoA + H(+)


name: H2O + O-(ADP-D-ribosyl)-L-tyrosyl-[protein] <=> ADP-D-ribose + L-tyrosyl-[protein]


name: L-histidyl-[protein] + N(7)-methyl-GTP <=> diphosphate + N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein]


name: MAPKAPK2 phosphorylates HSF1 (Drosophila melanogaster)


name: DS is cleaved from its proteoglycan (Homo sapiens)


name: H2O + S-inosyl-L-homocysteine = inosine + L-homocysteine


name: USP34 deubiquitinates AXIN1,AXIN2 (Canis familiaris)


name: isopentenyl diphosphate + neryl diphosphate => (2Z,6Z)-farnesyl diphosphate + diphosphate


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Danio rerio)


name: (9Z)-octadecenoate + (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + H(+) => (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O


name: EP300 is recruited to MYC and BCL2 genes (Mus musculus)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Rattus norvegicus)


name: a sterol ester + H2O = a fatty acid + a sterol + H(+)


name: voltage-gated monoatomic anion channel activity


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Homo sapiens)


name: (9Z)-octadecenoate + sphing-4-enine => H2O + N-(9Z-octadecenoyl)-sphing-4-enine


name: Association of procollagen type XXII (Bos taurus)


name: N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Danio rerio)


name: (2S)-2-phospholactate + GTP + H(+) <=> (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate


name: (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate = sulfate + sulforaphane


name: choline(in) + n H(+)(out) => choline(out) + n H(+)(in)


name: 11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione = (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoate


name: PIR oxygenates quercetin (Dictyostelium discoideum)


name: ATP + D-glyceraldehyde <=> ADP + D-glyceraldehyde 3-phosphate + H(+)


name: 8-oxo-GDP + H2O = 8-oxo-GMP + H(+) + phosphate


name: H(+) + NAD(+) + 2 reduced [cytochrome P450] => NADH + 2 oxidized [cytochrome P450]


name: GSTO1 dimer reduces methylarsonate to methylarsonite (Homo sapiens)


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: SLC29A1 transports RBV from cytosol to extracellular region (Canis familiaris)


name: CA4:Zn2+ hydrates CO2 to HCO3- (Drosophila melanogaster)


name: Cleavage of ethenocytosine by TDG glycosylase  (Gallus gallus)


name: Fluid-phase proteolytic cleavage of factor B (Gallus gallus)


name: IL4I1:FAD oxidises L-Phe to kPPV (Sus scrofa)


name: PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates (Sus scrofa)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Bos taurus)


name: 16-hydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => hexadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: NME1,2 hexamers phosphorylate RBV-DP (Caenorhabditis elegans)


name: HEXB cleaves the terminal GalNAc from DS (Rattus norvegicus)


name: O2 + pratensein + reduced [NADPH--hemoprotein reductase] = 5-hydroxypseudobaptigenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + CO2 + CoA => (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + malonyl-CoA


name: UDP-glucose-glycoprotein glucose phosphotransferase activity


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Canis familiaris)


name: ATP(in) + CoA(in) + decanoate(out) + H(+)(out) => AMP(in) + decanoyl-CoA(in) + diphosphate(in) + H(+)(in)


name: 2-hydroxybenzoyl-CoA + H(+) + NADH + O2 => 2,5-dihydroxybenzoyl-CoA + H2O + NAD(+)


name: H2O + neryl diphosphate = 1,8-cineole + diphosphate


name: (9Z)-hexadecenoate + 5-hydroxy-octadecanoate + H(+) => 5-(9Z-hexadecenoyloxy)-octadecanoate + H2O


name: (9Z)-octadecenoate + L-asparagine => H2O + N-(9Z-octadecenoyl)-L-asparagine


name: Association of Cdh1 with the APC/C (Mus musculus)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Mus musculus)


name: NAD(+) + succinate => fumarate + H(+) + NADH


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + sophoraflavanone B = H(+) + H2O + leachianone G + oxidized [NADPH--hemoprotein reductase]


name: miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + 3 H2O + miltiradien-20-al + 2 oxidized [NADPH--hemoprotein reductase]


name: (S)-3-amino-3-phenylpropanoate + pyruvate => 3-oxo-3-phenylpropanoate + L-alanine


name: delphinidin + UDP-alpha-D-galactose <=> delphinidin 3-O-beta-D-galactoside + H(+) + UDP


name: H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Danio rerio)


name: CYP26A1,B1 4-hydroxylate atRA (Danio rerio)


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Rattus norvegicus)


name: DSB inducing agents induce double strand DNA breaks (Homo sapiens)


name: RUNX2:CBFB binds the LGALS3 gene promoter (Homo sapiens)


name: AMP + diphosphate + L-tyrosinal + NADP(+) <=> ATP + H(+) + L-tyrosine + NADPH


name: (6E)-8-hydroxygeraniol + NADP(+) <=> (6E)-8-oxogeraniol + H(+) + NADPH


name: 2 ADP + 2 H(+) + hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 phosphate => 2 ATP + 2 H2O + hydrogenobyrinate + 2 L-glutamine


name: UDP + zolarsartan O-beta-D-glucuronoside => UDP-alpha-D-glucuronate + zolasartan


name: RUNX3 binds the NOTCH1 coactivator complex (Rattus norvegicus)


name: Movement of clathrin coated vesicles into early endosome (Mus musculus)


name: Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Sus scrofa)


name: ISGylation of host proteins (Sus scrofa)


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Bos taurus)


name: ethanolamine transmembrane transporter activity


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Dictyostelium discoideum)


name: 3-hydroxy-L-kynurenine(out) + L-tryptophan(in) => 3-hydroxy-L-kynurenine(in) + L-tryptophan(out)


name: (20S)-ginsenoside Rd + UDP-alpha-D-glucose <=> (20S)-ginsenoside Rb1 + H(+) + UDP


name: NAD(+) + pyridoxal => 4-pyridoxolactone + H(+) + NADH


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Gallus gallus)


name: USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Sus scrofa)


name: RUNX1 binds PRC1 complexes (Mus musculus)


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Rattus norvegicus)


name: (+)-dehydrodiconiferyl acid + a quinone <=> (+)-dehydrodiconiferyl acid ketone + a quinol


name: oxoglutarate dehydrogenase (succinyl-transferring) activity


name: FOXO3,FOXO4 bind STK11 gene promoter (Homo sapiens)


name: a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 2'-phosphate + H(+)


name: D-glyceraldehyde + H2O + NADP(+) = (R)-glycerate + 2 H(+) + NADPH


name: (2E)-geranyl diphosphate + umbelliferone <=> 8-geranylumbelliferone + diphosphate


name: valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Saccharomyces cerevisiae)


name: organic hydroxy compound transmembrane transporter activity


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Gallus gallus)


name: Nuclear JET binds CRY, facilitating its ubiquitination (Drosophila melanogaster)


name: Autocatalytic activation of MMP1 (Xenopus tropicalis)


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Sus scrofa)


name: (2S)-hesperidin + H2O = (2S)-hesperetin + rutinose


name: 3'-N-debenzoyltaxol + A + H2O => 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2


name: H2O + O-acyl-(R)-carnitine = (R)-carnitine + a fatty acid + H(+)


name: CYSLT2 binds LTC4,LTD4,LTE4 (Canis familiaris)


name: SMURF1/2 ubiquitinates PRICKLE1 (Danio rerio)


name: dimethylallyl diphosphate + H2O + isopentenyldehydrorhodopin => dihydrobisanhydrobacterioruberin + diphosphate


name: 5-fluorocytidine + ATP => 5-fluorocytidine 5'-phosphate + ADP + H(+)


name: 2-methylhexenoyl-CoA + reduced [electron-transfer flavoprotein] => 2-methylhexanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: H(+) + L-glutamyl-tRNA(Glu) + NADPH => (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Caenorhabditis elegans)


name: p52:RELB translocates from cytosol to nucleus (Bos taurus)


name: N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = H(+) + N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Bos taurus)


name: 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+) => 1-(5-phospho-beta-D-ribosyl)-ATP + H2O


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Drosophila melanogaster)


name: a 1-acylglycerone 3-phosphate + hexadecan-1-ol => 1-O-hexadecylglycerone 3-phosphate + a fatty acid + H(+)


name: Deubiquitinated PTEN translocates to the cytosol (Dictyostelium discoideum)


name: H2O2 + iminosuccinate => L-aspartate + O2


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA


name: an N-acyl-(4R)-4-hydroxysphinganine + H(+) + mannosyldiinositol-1-phosphate => an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O


name: SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Homo sapiens)


name: 15-hydroxypentadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA => 4-hydroxy-6-(16-hydroxy-2-oxohexadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: Translocation of PKC theta to plasma membrane (Schizosaccharomyces pombe)


name: ATP + S-sulfanyl-L-cysteine + tRNA(Cys) => (S)-sulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate


name: Defective B3GALTL does not transfer glucose to O-fucosyl-proteins (Homo sapiens)


name: a long-chain (3S)-3-hydroxy fatty acyl-CoA => a long-chain (2E)-enoyl-CoA + H2O


name: 3-chloro-L-alanine + thioglycolate <=> chloride + H(+) + S-carboxymethyl-L-cysteine


name: 3-oxohexanoyl-[ACP] + H(+) + NADPH = (3R)-hydroxyhexanoyl-[ACP] + NADP(+)


name: 2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> H(+) + hexadecanoate + sn-glycerol 3-phosphocholine


name: a 3'-end 2'-deoxyribonucleotide-3'-(L-tyrosyl phosphate)-DNA + H2O <=> a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H(+) + L-tyrosine


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Plasmodium falciparum)


name: 3-oxo-5,6-didehydrosuberyl-CoA + 2 H(+) + NADPH => 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + H2O + NADP(+)


name: 3-phenylpyruvate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-phenylalanine


name: Dephosphorylation of TYK2 by PTP1B (Rattus norvegicus)


name: S1PR1 binds S1PR1 agonists (Canis familiaris)


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Canis familiaris)


name: MSR1 (SCARA1, SR-A) binds ligands (Homo sapiens)


name: COPII coat binds TRAPPCII and RAB1:GDP (Bos taurus)


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Homo sapiens)


name: SHC1-2 bound to MET recruits GRB2:SOS1 (Canis familiaris)


name: IRAK interacts with TRAF6 (Mus musculus)


name: ERBB4s80 binds STMN1 gene (Homo sapiens)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Xenopus tropicalis)


name: Opsins act as GEFs for G alpha-t (Homo sapiens)


name: HTR1A binds HTR1A antagonists (Canis familiaris)


name: 2 benzoyl-CoA + L-ornithine => 2 CoA + 2 H(+) + N(2),N(5)-dibenzoyl-L-ornithine


name: HMGCR dimer reduces bHMG-CoA to MVA (Xenopus tropicalis)


name: acetyl-CoA + succinyl-CoA => 3-oxoadipyl-CoA + CoA


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: TLR4-induced ripoptosome assembly (Rattus norvegicus)


name: DARC  is a non-specific receptor for many chemokines (Sus scrofa)


name: (E)-sinapyl alcohol + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol + H(+) + UDP


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Rattus norvegicus)


name: a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)


name: 2 Fe(III)-[cytochrome c] + 2 thiosulfate => 2 Fe(II)-[cytochrome c] + 2 H(+) + tetrathionate


name: 2 N(omega)-hydroxy-L-arginine + NADPH + 2 O2 => H(+) + 2 H2O + 2 L-citrulline + NADP(+) + 2 nitric oxide


name: Recruited STAT5 is phosphorylated (Sus scrofa)


name: (3R)-hydroxybutanoate dimer + H2O <=> 2 (R)-3-hydroxybutanoate + H(+)


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Gallus gallus)


name: a 1,2-diacylglycerol + a fatty acid + H(+) => a triacylglycerol + H2O


name: (9Z)-hexadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = (9Z)-16-hydroxyhexadec-9-enoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DENND6A,B exchange GTP for GDP on RAB14 (Mus musculus)


name: STK11 (LKB1) phosphorylates NUAK1 (Canis familiaris)


name: TXLNA (IL14) binds syntaxin3 (Caenorhabditis elegans)


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Canis familiaris)


name: SRD5A3 reduces pPNOL to DCHOL (Bos taurus)


name: L1 interaction with Integrins (Xenopus tropicalis)


name: chloride(out) + L-pipecolate(out) + 2 Na(+)(out) = chloride(in) + L-pipecolate(in) + 2 Na(+)(in)


name: 2-oxoglutarate + O2 + octanoyl-CoA = 2-hydroxyoctanoyl-CoA + CO2 + succinate


name: MAD2 associates with the Mad1 kinetochore complex (Xenopus tropicalis)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Homo sapiens)


name: 2,5-dihydroxybenzoate + CoA + H(+) => 2,5-dihydroxybenzoyl-CoA + H2O


name: SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Rattus norvegicus)


name: H2O + N(2)-(4-aminobutanoyl)-L-lysine => 4-aminobutanoate + L-lysine


name: SLC50A1 transports Glc from cytosol to extracellular region (Xenopus tropicalis)


name: H(+) + hexadecanoyl-CoA + NADH => CoA + hexadecanal + NAD(+)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Caenorhabditis elegans)


name: 1-dodecanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA


name: Defective MPDU1 does not promote transfer of Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 by ALG12 (Homo sapiens)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Caenorhabditis elegans)


name: 1,4-diguanidinobutane + H2O => agmatine + urea


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Caenorhabditis elegans)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + H2O => 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H(+)


name: IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Homo sapiens)


name: GRB2:GAB1 binds to phosphorylated EGFR (Xenopus tropicalis)


name: 4-aminobutanal + H2O + NADP(+) => 4-aminobutanoate + 2 H(+) + NADPH


name: Activated PCLG1 dissociates from NTRK3 (Gallus gallus)


name: ADP(out) + dADP(in) = ADP(in) + dADP(out)


name: myo-inositol + phosphate => 1D-myo-inositol 4-phosphate + H2O


name: gamma-L-glutamyl-butirosin B <=> 5-oxo-L-proline + butirosin B


name: PKC-delta translocates to plasma membrane (Bos taurus)


name: Production of AA by iPLA2 upon FCGR activation (Rattus norvegicus)


name: 2-oxosuccinamate + H2O2 + NH4(+) => H2O + L-asparagine + O2


name: NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)


name: 3',5'-cyclic GMP(in) <=> 3',5'-cyclic GMP(out)


name: D-apionolactone + H2O => D-apionate + H(+)


name: Phosphorylation of WWTR1 (TAZ) by LATS2 (Mus musculus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Canis familiaris)


name: di-trans,octa-cis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl di-trans,octa-cis-undecaprenyl phosphate + GDP


name: 2 Na(+)(out) + taurohyodeoxycholate(out) <=> 2 Na(+)(in) + taurohyodeoxycholate(in)


name: G protein-coupled histamine receptor binding


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Xenopus tropicalis)


name: NAD(+) + ribitol => D-ribulose + H(+) + NADH


name: 4-methylsulfanyl-2-oxobutanoate + H(+) + NADPH => (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NADP(+)


name: N-acetyl-D-glucosamine 6-phosphate => N-acetyl-D-mannosamine 6-phosphate


name: 3beta,7alpha-dihydroxyandrost-5-en-17-one + NADP(+) => 3beta-hydroxy-5-androstene-7,17-dione + H(+) + NADPH


name: dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] <=> (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: (24S)-25-epoxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S,25)-epoxy-7alpha-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: "blood group B branched chain alpha-1,3-galactosidase"


name: SMAD6 gene expression is stimulated by RUNX2 and SMAD1 (Homo sapiens)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Rattus norvegicus)


name: Cap-bound mRNA is activated by helicases  (Canis familiaris)


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Danio rerio)


name: ATP + NH4(+) + XMP = AMP + diphosphate + GMP + 2 H(+)


name: SUMOylation of NR1I2 with SUMO3 (Bos taurus)


name: Initial activation of proMMP2 by MMP1, 7 (Gallus gallus)


name: RPS6KA1-dependent phosphorylation of MITF-M (Gallus gallus)


name: Mitochondrial BTD hydrolyses BCTN (Sus scrofa)


name: a primary alcohol + O2 = an aldehyde + H2O2


name: NLRP3 activation by elicitor proteins (Homo sapiens)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Bos taurus)


name: PRDX1 overoxidizes (Dictyostelium discoideum)


name: ANKH transports PPi from cytosol to extracellular region (Mus musculus)


name: 3alpha-hydroxyglycyrrhetinate + NADP(+) <=> 3-oxoglycyrrhetinate + H(+) + NADPH


name: RAC2 GDIs block activation of RAC2 (Caenorhabditis elegans)


name: Phosphorylated MOB1A proteins associate with LATS proteins (Canis familiaris)


name: P2Y2 receptor binds ATP and UTP (Canis familiaris)


name: a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-(4R)-hydroxysphinganine


name: L-phenylalanine(in) + L-serine(out) => L-phenylalanine(out) + L-serine(in)


name: Formation of VAF (virus-activated factor) complex (Bos taurus)


name: mitochondrial protein-transporting ATPase activity


name: SUMOylation of PML with SUMO3 (Bos taurus)


name: ATP + H(+) + H2O + O-ureido-D-serine = ADP + CO2 + D-cycloserine + NH4(+) + phosphate


name: Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Sus scrofa)


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Canis familiaris)


name: 2,2-dihydroxyspirilloxanthin = 2-oxospirilloxanthin + H2O


name: S-Farn-Me KRAS4B binds calmodulin (Drosophila melanogaster)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + ATP + CoA => (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-GTP = GTP + H(+) + lactate


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Schizosaccharomyces pombe)


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Homo sapiens)


name: ALK binds ligand midkine (MDK) (Homo sapiens)


name: Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Homo sapiens)


name: RAC1:GTP binds NOX3 complex (Sus scrofa)


name: salicyl alcohol + UDP-alpha-D-glucose => H(+) + salicin + UDP


name: H(+) + luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] + UDP => luteolin 7-O-beta-D-glucuronide + UDP-alpha-D-glucuronate


name: acetyl-CoA + streptothricin F => CoA + H(+) + N(beta)-acetylstreptothricin F


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Xenopus tropicalis)


name: SEMA4D interacts with Plexin-B1:Met (Rattus norvegicus)


name: chloride(out) + 2 Na(+)(out) + sarcosine(out) => chloride(in) + 2 Na(+)(in) + sarcosine(in)


name: H(+) + NADH + pyruvate => (R)-lactate + NAD(+)


name: a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP(+) = an (R)-2-alkyl-3-oxoalkanoate + H(+) + NADPH


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = H2O + 2 oxidized [adrenodoxin] + secalciferol


name: MEOS oxidizes ethanol to acetaldehyde (Dictyostelium discoideum)


name: 7alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase]


name: ULK1 is dephosphorylated (Rattus norvegicus)


name: NLRP3 activation by small molecules (Canis familiaris)


name: type 1 parathyroid hormone receptor binding


name: a long-chain (2E)-enoyl-CoA + H2O => a long-chain (3S)-3-hydroxy fatty acyl-CoA


name: 3-(all-trans-heptaprenyl)benzene-1,2-diol + H2O + NADP(+) => 2-all-trans-heptaprenylphenol + H(+) + NADPH + O2


name: coelenterazine h + O2 <=> CO2 + excited coelenteramide h monoanion + H(+) + hnu


name: 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP => 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+)


name: ATP + H2O + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(in) = ADP + H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(out) + phosphate


name: PPM1D dephosphorylates RUNX2 (Drosophila melanogaster)


name: 2-phenylacetaldehyde + AH2 + NH4(+) => 2-phenylethylamine + A + H2O


name: 2 A + 2 AMP + 2 diphosphate + H(+) + N-benzoyl-L-phenylalaninol => 2 AH2 + 2 ATP + benzoate + L-phenylalanine


name: ALOX5 is phosphorylated by MAPKAP2 (Bos taurus)


name: Dephosphorylation of phospho-Cdh1 (Gallus gallus)


name: AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Caenorhabditis elegans)


name: UDP-alpha-D-galactose(in) + UDP-N-acetyl-alpha-D-galactosamine(out) <=> UDP-alpha-D-galactose(out) + UDP-N-acetyl-alpha-D-galactosamine(in)


name: Activation of proMMP8 (Caenorhabditis elegans)


name: (S)-malate(in) + 2 thiosulfate(out) => (S)-malate(out) + 2 thiosulfate(in)


name: Proteasome-mediated degradation of PolyUb-FBXL7 (Rattus norvegicus)


name: MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) (Drosophila melanogaster)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: RUNX1 binds the SWI/SNF complex (Bos taurus)


name: Cleavage of the signal peptide of Preproghrelin (Homo sapiens)


name: H(+) + NADPH + O2 + tetracycline <=> 11a-hydroxytetracycline + H2O + NADP(+)


name: MSH2:MSH6 exchanges ADP for ATP (Canis familiaris)


name: a N-(2-hydroxyacyl)sphing-4-enine + UDP-alpha-D-galactose <=> H(+) + N-(2-hydroxyacyl)-beta-D-galactosyl-sphing-4-enine + UDP


name: dimethylallyl diphosphate + H2O + isopentenyldehydrorhodopin = dihydrobisanhydrobacterioruberin + diphosphate


name: (E)-sinapyl alcohol + acetyl-CoA = (E)-sinapoyl actetate + CoA


name: 3-oxochola-4,17-dien-22-oyl-CoA + H2O <=> 17-hydroxy-3-oxochol-4-en-22-oyl-CoA


name: 4 H(+) + uroporphyrinogen III <=> 4 CO2 + coproporphyrinogen III


name: RhCG mediates ammonium influx into kidney collecting duct cells (Drosophila melanogaster)


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Bos taurus)


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Danio rerio)


name: (Z)-3-aminoacrylate + H(+) + H2O <=> 3-oxopropanoate + NH4(+)


name: Keratin filaments bind cell-cell adhesion complexes (Canis familiaris)


name: chloride(in) + dopamine(in) + 2 Na(+)(in) => chloride(out) + dopamine(out) + 2 Na(+)(out)


name: SREBP1A,2 binds the DHCR7 promoter (Homo sapiens)


name: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Caenorhabditis elegans)


name: glycine + octanoyl-CoA = CoA + H(+) + N-octanoylglycine


name: MYD88 binds to TUB (Drosophila melanogaster)


name: Cdc45 associates with the pre-replicative complex at the origin (Drosophila melanogaster)


name: 3 H(+) + hydrogen sulfide + L-aspartate 4-semialdehyde + reduced 2[4Fe-4S]-[ferredoxin] <=> H2O + L-homocysteine + oxidized 2[4Fe-4S]-[ferredoxin]


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A => 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: Basigin interacts with CD43 (Canis familiaris)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + 2 O2 => (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E)-docosapentaenoate


name: 2-hydroxy-3-oxosuccinate + 2 H(+) + NADH => (R)-glycerate + CO2 + NAD(+)


name: Activated NTRK3 promotes SRC autophosphorylation (Gallus gallus)


name: EP1 receptor can bind PGE2 (Mus musculus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Sus scrofa)


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Canis familiaris)


name: an N-(fatty acyl)-L-glutamine + H2O <=> a fatty acid + L-glutamine


name: Active FLT3 dimer binds GRB2 (Homo sapiens)


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Drosophila melanogaster)


name: H2O + N-acetyl-D-glucosamine + O2 = H(+) + H2O2 + N-acetyl-D-glucosaminate


name: C-19 gibberellin 2-beta-dioxygenase activity


name: 6,7-dichloro-L-tryptophan + FAD + 2 H2O => 7-chloro-L-tryptophan + chloride + FADH2 + O2


name: NPPA(124-151) binds NPR1 (Xenopus tropicalis)


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Mus musculus)


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Homo sapiens)


name: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methyladenosine(1067) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + gamma-curcumene


name: chrodrimanin E + CO2 + H2O + succinate => 2-oxoglutarate + chrodrimanin H + O2


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Dictyostelium discoideum)


name: AKT1S1 (PRAS40) binds mTORC1 (Sus scrofa)


name: UBA1 adenylates ubiquitin in the cytosol (Schizosaccharomyces pombe)


name: ERBB3 binds RNF41 ubiquitin ligase (Bos taurus)


name: (2E,6E)-farnesyl diphosphate = (-)-alpha-isocomene + diphosphate


name: (9Z)-hexadecenoyl-CoA + hexadecan-1-ol <=> 1-O-hexadecyl (9Z)-hexadecenoate + CoA


name: (S)-1-phenylethanol + NAD(+) <=> acetophenone + H(+) + NADH


name: Formation of MCM2-7 complex (Saccharomyces cerevisiae)


name: 2'-deoxyribonucleotide-DNA + H(+) + S-methyl-L-cysteinyl-[protein] => (2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-[protein]


name: CGRP receptor can bind calcitonin gene-related peptides (Bos taurus)


name: RUNX3 binds the NOTCH1 coactivator complex (Canis familiaris)


name: 2 (S)-methylmalonyl-CoA + 10 H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 3 malonyl-CoA + 5 NADPH => C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)


name: a plastoquinone + (n+1) H(+)(in) + NADPH <=> a plastoquinol + n H(+)(out) + NADP(+)


name: a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H2O = a 5'-end dephospho-2'-deoxyribonucleoside-DNA + phosphate


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Sus scrofa)


name: (R)-8-oxocitronellyl enol + NADP(+) <=> (6E)-8-oxogeranial + H(+) + NADPH


name: a ubiquinol + 2 H(+)(in) + nitrate <=> a ubiquinone + 2 H(+)(out) + H2O + nitrite


name: 2 Fe(III)-[cytochrome c] + H2O + pseudooxynicotine => 4-oxo-4-(pyridin-3-yl)butanal + 2 Fe(II)-[cytochrome c] + 2 H(+) + methylamine


name: 3,4-dihydroxybenzoate + CO2 + NADH => (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Gallus gallus)


name: ATM phosphorylates TP53BP1 at DNA DSBs (Bos taurus)


name: glutamate:gamma-aminobutyric acid antiporter activity


name: ADP + arsenite(out) + H(+) + phosphate => arsenite(in) + ATP + H2O


name: 17alpha-estradiol 17-O-(beta-D-glucuronate) + H(+) + UDP => 17alpha-estradiol + UDP-alpha-D-glucuronate


name: Recruitment of XPA and release of CAK  (Drosophila melanogaster)


name: SPPL2a/b cleaves TNF(1-76) (Rattus norvegicus)


name: ATP + H(+) + NADPH + pentanoate => AMP + diphosphate + NADP(+) + pentanal


name: PKC-delta is activated (Xenopus tropicalis)


name: acetyl-CoA + H2O + oxaloacetate <=> citrate + CoA + H(+)


name: linear 1,3-beta-D-glucan synthase activity


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Rattus norvegicus)


name: Adenylate cyclase converts ATP into cyclic AMP (Dictyostelium discoideum)


name: PRKCI phosphorylates ELF3 (Rattus norvegicus)


name: (S)-lactate + NAD(+) => H(+) + NADH + pyruvate


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Mus musculus)


name: Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 (Rattus norvegicus)


name: myo-inositol + phosphate => 1D-myo-inositol 2-phosphate + H2O


name: (2S)-2-acetolactate + H(+) => (R)-acetoin + CO2


name: 4-(gamma-L-glutamylamino)butanal + H2O + NAD(+) <=> 4-(gamma-L-glutamylamino)butanoate + 2 H(+) + NADH


name: 3-methylbutanal + H(+) + NADH => 3-methylbutanol + NAD(+)


name: glycine + tetradecanoyl-CoA <=> CoA + H(+) + N-tetradecanoylglycine


name: (R)-mandelamide + H2O <=> (R)-mandelate + NH4(+)


name: Fe(III)-heme b-[protein] + H2O + nitric oxide => Fe(II)-heme b-[protein] + 2 H(+) + nitrite


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Danio rerio)


name: poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Xenopus tropicalis)


name: benzoate + H(+) + NADH + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Danio rerio)


name: deoxynogalonate + O2 => H(+) + H2O + nogalonate


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA => 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: Autophosphorylation of PAK (Homo sapiens)


name: 6'''-deamino-6'''-hydroxyneomycin C + acetate => 2'''-acetyl-6'''-hydroxyneomycin C + H2O


name: ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Mus musculus)


name: CLPXP binds mitochondrial matrix proteins (Bos taurus)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Xenopus tropicalis)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: SPRY2 translocates to the plasma membrane (Sus scrofa)


name: (-)-alpha-acorenol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: RNASEL cleaves cellular ssRNA (Sus scrofa)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Sus scrofa)


name: (3Z)-hex-3-en-1-yl acetate + CoA => (3Z)-hex-3-en-1-ol + acetyl-CoA


name: a 1-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: 2-oxoadipate + acetyl-CoA + H2O => (R)-dihomocitrate + CoA + H(+)


name: G-protein beta-gamma subunits rebind the alpha-GDP subunit (Gallus gallus)


name: a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + a 5'-end dephospho-ribonucleoside-RNA => a ribonucleotidyl-ribonucleotide-RNA + GMP + H(+)


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate <=> diphosphate + ent-13-epi-manoyl oxide


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Rattus norvegicus)


name: 4-O-(beta-D-glucosyl)-trans-sinapate + H(+) + UDP => (E)-sinapate + UDP-alpha-D-glucose


name: Re-integration of insulin receptor into plasma membrane (Gallus gallus)


name: (9Z)-hexadecenoate + ATP + CoA => (9Z)-hexadecenoyl-CoA + AMP + diphosphate


name: OGG1beta G12E does not translocate to mitochondria (Homo sapiens)


name: a (4S)-2,3-dehydroflavan-3,4-diol + H(+) = a 4-H-anthocyanidin with a 3-hydroxy group + H2O


name: myo-inositol + phosphate => 1D-myo-inositol 5-phosphate + H2O


name: Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Canis familiaris)


name: alpha-secretase cleaves the p75NTR extracellular domain (Homo sapiens)


name: 3 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 O2 => 3 CO2 + 3 formaldehyde + L-lysyl(4)-[histone H3] + 3 succinate


name: Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL (Mus musculus)


name: FGFR3b binds to FGF (Caenorhabditis elegans)


name: PAK1,2,3 phosphorylates MAPK6,4 (Rattus norvegicus)


name: a 5'-end guanosine-5'-diphospho-5'-(2'-deoxyribonucleoside)-DNA + H2O <=> a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + GMP + 2 H(+)


name: D-xylobiose + O2 => D-xylobiono-1,5-lactone + H2O2


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Rattus norvegicus)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Caenorhabditis elegans)


name: Translocation of CaN:CaM:NFAT to nucleus (Gallus gallus)


name: Activated FYN binds GRIN2B (Homo sapiens)


name: ergosterol + UDP-alpha-D-glucose <=> ergosteryl 3-beta-D-glucoside + H(+) + UDP


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate => (3R)-3-hydroxy-3-(thiiran-2-yl)propanenitrile + sulfate


name: GSS:Mg2+ dimer synthesizes GSH (Schizosaccharomyces pombe)


name: Importin-8 imports AGO2:miRNA into the nucleus (Mus musculus)


name: CSNK1D phosphorylates SEC23 (Saccharomyces cerevisiae)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Danio rerio)


name: Cleavage of Procaspase-7 by the apoptosome (Canis familiaris)


name: Cleavage of uracil by TDG glycosylase (Canis familiaris)


name: D-glucose 6-phosphate + NAD(+) => 6-phospho-D-glucono-1,5-lactone + H(+) + NADH


name: transcription elongation factor activity


name: [(1->4)-beta-D-mannosyl](n) + phosphate => [(1->4)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate


name: Spherical HDL binds C and E apolipoproteins (Homo sapiens)


name: a 2'-deoxyribonucleoside 3'-phosphate + H2O => a 2'-deoxyribonucleoside + phosphate


name: STUB1 polyubiquitinates RUNX2 (Canis familiaris)


name: Factor H binds to membrane-associated C3b (Canis familiaris)


name: HLCS biotinylates PC:Mn2+ (Canis familiaris)


name: IFNAR1:TYK2 binds TYK2 inhibitors (Mus musculus)


name: ATP + L-seryl-[low-density-lipoprotein receptor] => ADP + H(+) + O-phospho-L-seryl-[low-density-lipoprotein receptor]


name: SLC43A1 (LAT3)-mediated uptake of large neutral amino acids (Canis familiaris)


name: PXLP-K56-SRR dimer deaminates D-Ser (Dictyostelium discoideum)


name: ATP + L-threonyl-[Goodpasture antigen-binding protein] = ADP + H(+) + O-phospho-L-threonyl-[Goodpasture antigen-binding protein]


name: prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer (Rattus norvegicus)


name: 16alpha-hydroxydehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in) => 16alpha-hydroxydehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: bilirubin transmembrane transporter activity


name: 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine => 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + H(+) + S-adenosyl-L-homocysteine


name: MTMR6 binds MTMR9 (Drosophila melanogaster)


name: ZnT1 mediates the efflux of zinc from the cell (Gallus gallus)


name: (5S)-hydroperoxy-(6E,8Z)-eicosadienoate => (5Z,8Z)-eicosadienoate + O2


name: Phosphorylation of MEK4 by MEKK1 (Homo sapiens)


name: cadaverine + H2O + O2 => 5-aminopentanal + H2O2 + NH4(+)


name: 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate = dihydroxyacetone phosphate + L-aspartate 4-semialdehyde


name: hydrogencarbonate(in) + selenite(in) + Zn(2+)(in) => hydrogencarbonate(out) + selenite(out) + Zn(2+)(out)


name: ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Xenopus tropicalis)


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Dictyostelium discoideum)


name: Joining of adjacent Okazaki fragments (Drosophila melanogaster)


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Gallus gallus)


name: ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA (Rattus norvegicus)


name: 13-hydroxy-octadecanoate + H(+) + octadecanoate => 13-octadecanoyloxy-octadecanoate + H2O


name: H2O + N-formyl-L-kynurenine = formate + H(+) + L-kynurenine


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + 2 H2O + NAD(+) = (4S)-4-hydroxy-L-glutamate + H(+) + NADH


name: CTP(out) + IDP(in) => CTP(in) + IDP(out)


name: Phosphorylation of IFNGR1 by JAK kinases (Danio rerio)


name: an n-alkanal + NAD(+) <=> an alk-2-enal + H(+) + NADH


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 6alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate => (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2


name: CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: PI is hydrolyzed to 2-acyl LPI by PLA2[13] (Rattus norvegicus)


name: H(+) + ilicicolin C + NADPH + O2 = ascochlorin + 2 H2O + NADP(+)


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-acyl-2-[(7Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: STAT4 binds p-Y-IL23R in IL23:IL23 receptor (Mus musculus)


name: (9Z,12Z)-octadecadienoate + O2 => (13R)-hydroperoxy-(9Z,11E)-octadecadienoate


name: CoA + H(+) + N-eicosanoyl-taurine => eicosanoyl-CoA + taurine


name: (E,E)-feruperate + O2 + reduced [NADPH--hemoprotein reductase] => (E,E)-piperate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate => all-trans-decaprenyl diphosphate + 7 diphosphate


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Mus musculus)


name: TOPORS SUMOylates IKBKE with SUMO1 (Homo sapiens)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Caenorhabditis elegans)


name: PLK1 phosphorylates BORA (Caenorhabditis elegans)


name: AKT can phosphorylate NR4A1 (NUR77) (Caenorhabditis elegans)


name: (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + NAD(+) => (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H(+) + NADH


name: RHOA binds effectors at the ER membrane (Sus scrofa)


name: an acyl-CoA + episterol <=> an episterol ester + CoA


name: Adenylate cyclase produces cAMP (Rattus norvegicus)


name: 2-cis-(+)-abscisate + UDP-alpha-D-glucose = beta-D-glucopyranosyl cis-(+)-abscisate + UDP


name: 10-oxooctadecanoate + H(+) + NADH => 10-hydroxyoctadecanoate + NAD(+)


name: H2O + neurotensin-(1-8) <=> L-arginine + neurotensin-(1-7)


name: Bcl-2 and Bcl-XL bind NLRP1 (Gallus gallus)


name: 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA <=> 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: Edg-3 sphingosine 1-phosphate receptor binding


name: poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] (Homo sapiens)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Gallus gallus)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+) => a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Rattus norvegicus)


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene + A => 1,1'-dihydroxy-3,4-didehydro-1,2-dihydrolycopene + AH2


name: SEMA7A binds to PLXNC1 (Caenorhabditis elegans)


name: an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: APEH hydrolyses NAc-Ser-protein (Dictyostelium discoideum)


name: GLB1 hydrolyses linker chain(2) (Rattus norvegicus)


name: p38 MAPK activation by VEGFR (Bos taurus)


name: RIP3 binds TRIF to mediate necroptosis (Mus musculus)


name: KAT5 acetylates ATM at DNA DSBs (Mus musculus)


name: RANBP2 SUMOylates PML with SUMO2 (Bos taurus)


name: RHOA binds effectors at the ER membrane (Canis familiaris)


name: Phosphorylated SMO changes conformation and is activated (Drosophila melanogaster)


name: ATP + Co(2+) + H2O + hydrogenobyrinate a,c-diamide <=> ADP + cob(II)yrinate a,c diamide + 5 H(+) + phosphate


name: monodehydroascorbate reductase (NADH) activity


name: N-acetylserotonin + S-adenosyl-L-methionine = H(+) + melatonin + S-adenosyl-L-homocysteine


name: FGFR2IIIa TM binds ligand and full length receptors to inhibit signaling (Homo sapiens)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Schizosaccharomyces pombe)


name: (Z)-2-methylureidoacrylate + H(+) + H2O <=> (Z)-2-methylaminoacrylate + CO2 + NH4(+)


name: 5 H(+) + L-pipecolate + malonyl-CoA + 3 NADPH = (1R,8aS)-octahydroindolizin-1-ol + CO2 + CoA + 2 H2O + 3 NADP(+)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Danio rerio)


name: racemase and epimerase activity, acting on carbohydrates and derivatives


name: C-ter TLR7 dimer binds imiquimod (Sus scrofa)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: 1'-hydroxy-demethylspheroidene + AH2 => 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene + A


name: perivine + S-adenosyl-L-methionine = 2 H(+) + S-adenosyl-L-homocysteine + vobasine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) <=> 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + a 1,2-diacyl-sn-glycerol


name: ITCH polyubiquitinates TP73 (Homo sapiens)


name: 6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+) => 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH


name: H(+) + keto-D-tagatose + NADH => galactitol + NAD(+)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Plasmodium falciparum)


name: Cleavage of hypoxanthine by MPG glycosylase (Bos taurus)


name: (4S)-4-hydroxy-2-oxoglutarate <=> glyoxylate + pyruvate


name: ATP + L-tryptophan = diphosphate + L-tryptophyl-5'-AMP


name: H(+) + L-homocitrulline + phosphate => carbamoyl phosphate + L-lysine


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Canis familiaris)


name: (E,E)-sorbate + H(+) = (E)-1,3-pentadiene + CO2


name: adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + H(+) => 3'-phosphoadenylyl sulfate + dopamine


name: CDKN1B is phosphorylated in response to estrogen (Mus musculus)


name: PDE6 hydrolyses cGMP to GMP (Xenopus tropicalis)


name: SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ (Gallus gallus)


name: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H(+) + NADPH => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+)


name: an aldose + H(+) + NADH => an alditol + NAD(+)


name: NR1D1 (REV-ERBA) binds heme, the CLOCK gene, and recruits corepressors (Homo sapiens)


name: 6-hydroxyphenazine-1-carboxylate + 2 H(+) + NADH + O2 <=> 1,6-dihydroxyphenazine + CO2 + H2O + NAD(+)


name: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA => 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O


name: 3-O-(alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + H(+) + UDP


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Gallus gallus)


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Mus musculus)


name: S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = H(+) + S-methyl-5'-thioadenosine + thermospermine


name: H2O + N-formylmethanofuran => formate + methanofuran


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Bos taurus)


name: AKR1C3 reduces atRAL to atROL (Homo sapiens)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)


name: TP53 binds the FANCC gene (Homo sapiens)


name: Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids (Mus musculus)


name: HMIT co-transports myo-inositol with a proton (Caenorhabditis elegans)


name: (S)-lactate(out) + 2 Na(+)(out) <=> (S)-lactate(in) + 2 Na(+)(in)


name: eIF3 and eIF1A bind to the 40S subunit (Sus scrofa)


name: a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GP1c (d18:1(4E)) + CMP + H(+)


name: GDP-beta-L-fucose + L-threonyl-[protein] => 3-O-(alpha-L-fucosyl)-L-threonyl-[protein] + GDP + H(+)


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate


name: Endocytosis of protein 3a (Homo sapiens)


name: Formation of C-strand Okazaki fragments (Rattus norvegicus)


name: Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Rattus norvegicus)


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Saccharomyces cerevisiae)


name: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+) = a (3R)-2'-hydroxyisoflavanone + H(+) + NADPH


name: 2xENPP1 hydrolyzes FAD to FMN (Schizosaccharomyces pombe)


name: MAP2K6 phosphorylates PIP4K2B (Bos taurus)


name: 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA => 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA


name: CSPG is secreted (Drosophila melanogaster)


name: 6-demethylmitomycin A + S-adenosyl-L-methionine => mitomycin A + S-adenosyl-L-homocysteine


name: chloride(out) + D-alanine(out) + 2 Na(+)(out) <=> chloride(in) + D-alanine(in) + 2 Na(+)(in)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)


name: (2R,4S)-2,4-diaminopentanoate + H2O + NADP(+) = (2R)-2-amino-4-oxopentanoate + H(+) + NADPH + NH4(+)


name: CoA + H(+) + N-dodecanoyl-taurine => dodecanoyl-CoA + taurine


name: [phosphate](n) + a dolichyl diphosphate <=> [phosphate](n+1) + a dolichyl phosphate


name: Autocatalytic activation of proMMP2 (Canis familiaris)


name: Binding of ADAR1 homodimer to dsRNA duplex (Mus musculus)


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Dictyostelium discoideum)


name: cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine <=> H(+) + N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine


name: Binding of CBL to EGFR (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + taurochenodeoxycholate => adenosine 3',5'-bisphosphate + H(+) + taurochenodeoxycholate 7-sulfate


name: Class IV antihypertensives bind LTCC multimer (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate <=> (-)-7-epi-alpha-selinene + diphosphate


name: 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate => H2O + monacolin L carboxylate


name: GRB2-1:SOS1 binds p-Y-SHC (Canis familiaris)


name: fluorescent chlorophyll catabolite monooxygenase (deformylase) activity


name: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H(+) + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite


name: "mitogen-activated protein kinase kinase kinase"


name: 1-O-(trans-cinnamoyl)-beta-D-glucose + UDP => (E)-cinnamate + UDP-alpha-D-glucose


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Gallus gallus)


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Xenopus tropicalis)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Plasmodium falciparum)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Mus musculus)


name: (25S)-3beta-hydroxy-5-cholestenoyl-CoA + AMP + diphosphate => (25S)-3beta-hydroxy-5-cholestenoate + ATP + CoA


name: cholesterol + PAPS => cholesterol sulfate + PAP (Bos taurus)


name: H2O + N-(9Z-octadecenoyl)-L-leucine => (9Z)-octadecenoate + L-leucine


name: TGN-lysosomal vesicle coat assembly (Bos taurus)


name: reduced coenzyme F420 dehydrogenase activity


name: IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Rattus norvegicus)


name: H(+)(out) + L-glutamine(in) + Na(+)(in) => H(+)(in) + L-glutamine(out) + Na(+)(out)


name: SMURF1/2 dissociates from ub-PTCH1 (Gallus gallus)


name: H2O + N(omega)-alpha-(ADP-D-ribosyl)-L-arginyl-[dinitrogen reductase] = ADP-D-ribose + L-arginyl-[dinitrogen reductase]


name: CDC42:GTP binds CBL:Beta-Pix (Canis familiaris)


name: H2O + N-eicosanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = (9Z)-octadecenoate + H(+) + N-eicosanoyl-sn-glycero-3-phosphoethanolamine


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Homo sapiens)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Mus musculus)


name: L-histidyl-[protein] + N(7)-methyl-GTP = diphosphate + N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein]


name: H2O + octanoyl-CoA <=> CoA + H(+) + octanoate


name: pro-RAS proteins are farnesylated (Danio rerio)


name: a dipeptide(out) + ATP + H2O = a dipeptide(in) + ADP + H(+) + phosphate


name: (R,S)-butane-2,3-diol + NAD(+) <=> (R)-acetoin + H(+) + NADH


name: uridine(65) in tRNA => pseudouridine(65) in tRNA


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Canis familiaris)


name: L-isoleucyl-L-leucine + neurotensin(1-11) => H2O + neurotensin


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Homo sapiens)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Mus musculus)


name: (3R)-3-hydroxybutanoyl-CoA + H2O = (R)-3-hydroxybutanoate + CoA + H(+)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Xenopus tropicalis)


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Bos taurus)


name: PTK6 phosphorylates KHDRBS1 (Homo sapiens)


name: Growing HA is extruded from the cell by ABCC5 (Danio rerio)


name: 9-decenoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-(non-8-en-1-yl)-pyran-2-one + 2 CO2 + 3 CoA


name: Growth hormone receptor dimerizes (Gallus gallus)


name: 3beta-androst-5-en-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3beta-androst-5-en-17-one 3-O-(beta-D-glucuronate)


name: 4-methyl-2-oxopentanoate + H2O2 => 2-hydroxy-4-methylpentanoate + O2


name: Active LTK phosphorylates IRS1 (Rattus norvegicus)


name: (+)-dehydrodiconiferyl acid + 2 a quinone + H2O <=> (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Sus scrofa)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Bos taurus)


name: PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Bos taurus)


name: p25-bound CDK5 phosphorylates CDC25B (Homo sapiens)


name: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 11-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate


name: RHOB translocates to the endosome membrane (Mus musculus)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Gallus gallus)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Xenopus tropicalis)


name: MIB2 ubiquitinates CYLD at K338, K530 (Bos taurus)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Rattus norvegicus)


name: AH2 + prostaglandin G2 = A + H2O + prostaglandin H2


name: NTRK3 dimers trans-autophosphorylate (Mus musculus)


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hexadecanoyloxy-octadecanoate


name: ASA- (GI) translocates from cytosol to extracellular region (Homo sapiens)


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Bos taurus)


name: MRRF binds 55S ribosome:mRNA:tRNA (Drosophila melanogaster)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O <=> (9Z)-octadecenoate + 1,3-di-(9Z-octadecenoyl)-glycerol + H(+)


name: diphosphate + ent-manool => ent-copalyl diphosphate + H2O


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Mus musculus)


name: Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Drosophila melanogaster)


name: Homer1,2,3 binds mGluR1a,5 (Rattus norvegicus)


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: 3,5,7,9,11-pentaoxododecanoyl-[ACP] <=> 6,8-dihydroxy-3-(2-oxopropyl)-isocoumarin + H2O + holo-[ACP]


name: oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor


name: H2O + N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) <=> 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: histone H3K56 acetyltransferase activity


name: LIN7, CASK and APBA1 bind (Drosophila melanogaster)


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Mus musculus)


name: Defective CHSY1 does not transfer GlcA to chondroitin (Homo sapiens)


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Bos taurus)


name: 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phospho-L-serine + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + octadecanoyl-CoA


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: Vamp2 associated secretory vesicle to plasma membrane transport (Canis familiaris)


name: 3-amino-4-hydroxybenzoate + H(+) + NADPH + O2 => 3-amino-2,4-dihydroxybenzoate + H2O + NADP(+)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Schizosaccharomyces pombe)


name: glutarate(in) + prostaglandin F2alpha(out) <=> glutarate(out) + prostaglandin F2alpha(in)


name: 5-hydroxymethyluracil + CO2 + succinate => 2-oxoglutarate + O2 + thymine


name: NAD(+) + S-(2-aminoethyl)-L-cysteine <=> (4S)-5,6-dihydro-4H-1,3-thiazine-4-carboxylate + 2 H(+) + NADH + NH4(+)


name: anthocyanin A6 + malonyl-CoA => anthocyanin A8 + CoA


name: Formation of MCM2-7 complex (Canis familiaris)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Bos taurus)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: ULK1 phosphorylates Beclin-1 (Homo sapiens)


name: C2CD3 binds the mother centriole (Sus scrofa)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Homo sapiens)


name: AMP(in) + diphosphate(in) + H(+)(in) + tetradecanoyl-CoA(in) => ATP(in) + CoA(in) + H(+)(out) + tetradecanoate(out)


name: (E)-caffeyl aldehyde + CoA + NADP(+) <=> (E)-caffeoyl-CoA + H(+) + NADPH


name: Enzyme-bound ATP is released (Rattus norvegicus)


name: Noradrenaline clearance from the synaptic cleft (Bos taurus)


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Canis familiaris)


name: 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol => calcitetrol + H2O + 2 oxidized [adrenodoxin]


name: Rnd1 interacts with Plexin-B1:Sema4D (Gallus gallus)


name: p-S MAPKAPK5 phosphorylates HSPB1 (Homo sapiens)


name: acetone + H(+) + NADH + O2 <=> H2O + hydroxyacetone + NAD(+)


name: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal


name: acetyl-CoA + tryptamine = CoA + H(+) + N-acetyltryptamine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine => H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine


name: PP2A methylation by LCMT1 (Caenorhabditis elegans)


name: SHC1 binds P-ERBB4 isoform dimers (Bos taurus)


name: 2-oxoglutarate + O2 + pentyl sulfate <=> CO2 + H(+) + pentanal + succinate + sulfate


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O => diphosphate + sesterfisherol


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Caenorhabditis elegans)


name: GSTZ1 dimer dehalogenates DCA (Bos taurus)


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: cAMP hydrolysis by Cam-PDE 1 (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O <=> a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)


name: FGFR2b binds to FGF (Caenorhabditis elegans)


name: 2beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + testosterone


name: HYAL1 hydrolyses (HA)50 (Canis familiaris)