name: granulocyte macrophage colony-stimulating factor complex binding


name: HDAC8 deacetylates histones (Gallus gallus)


name: 2 H(+) + NADH + O2 + salicylate <=> catechol + CO2 + H2O + NAD(+)


name: The bound receptor dimerizes (Xenopus tropicalis)


name: SULT1A3,4 dimers sulfate DA to DAOS (Sus scrofa)


name: ATP + H2O + K(+)(in) => ADP + H(+) + K(+)(out) + phosphate


name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex (Gallus gallus)


name: a medium-chain (3S)-3-hydroxyacyl-CoA => a medium-chain (2E)-enoyl-CoA + H2O


name: Aquaporin-9 passively transports glycerol into cell (Caenorhabditis elegans)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Drosophila melanogaster)


name: 1(F)-beta-D-fructosylsucrose + D-glucose => 2 sucrose


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Schizosaccharomyces pombe)


name: GPR35 binds kynurenic acid (Rattus norvegicus)


name: TRAF6/or TRAF2 ubiquitination within dsRNA:Mda5:Ips1:Traf6/ or Traf2 complex (Gallus gallus)


name: Degradation of Ub-SMAD7 (Rattus norvegicus)


name: all-trans-lycopaoctaene + 2 diphosphate + NADP(+) => 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADPH


name: (9Z,12Z)-octadecadienoate + O2 = (13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Canis familiaris)


name: PDCL binds G-protein beta and TRiC/CCT (Xenopus tropicalis)


name: (+)-copalyl diphosphate + H2O => diphosphate + nezukol


name: AH2 + gentamicin X2 + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + A + geneticin + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: Excision of 8-oxoguanine by OGG1 glycosylase (Canis familiaris)


name: a 1,2-diacyl-sn-glycerol + N-(hexacosanoyl)-sphinganine-1-(1D-myo-inositol) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-hexacosanoylsphinganine


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-glucosamine = beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + H(+) + UDP


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Drosophila melanogaster)


name: Cho transports from the extracellular space to the cytosol (Xenopus tropicalis)


name: Protesomal degradation of K48polyUb-TRAF3 (Sus scrofa)


name: hexadecan-1-ol + NAD(+) => H(+) + hexadecanal + NADH


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + H(+) + phosphate


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Mus musculus)


name: a sphingomyelin(in) => a sphingomyelin(out)


name: (E)-caffeate + hydrocaffeoyl-CoA <=> (E)-caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)propanoate


name: Exocytosis of Proactivator polypeptide (Homo sapiens)


name: [thioredoxin]-disulfide + prostamide F2alpha = [thioredoxin]-dithiol + prostamide H2


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] <=> H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein]


name: Inactivation of Wee1 kinase (Danio rerio)


name: alpha-D-glucose 6-phosphate => beta-D-glucose 6-phosphate


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Sus scrofa)


name: SEC24A,B:SEC23A bind SEC22B (Sus scrofa)


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Plasmodium falciparum)


name: AMP + diphosphate + N(4)-acetylcytidine(34) in elongator tRNA(Met) => acetate + ATP + cytidine(34) in elongator tRNA(Met)


name: 2-deoxy-scyllo-inosamine + NADP(+) = 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADPH


name: NAD(+) + spermidine <=> dehydrospermidine + H(+) + NADH


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Gallus gallus)


name: H2O + L-isoleucine-(+)-7-isojasmonate = (+)-7-isojasmonate + L-isoleucine


name: Trans-autophosphorylation of ERBB2 heterodimers (Danio rerio)


name: laricitrin + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + syringetin


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Xenopus tropicalis)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Danio rerio)


name: H(+) + methyl isocyanate + viridicatin => (-)-cyclopenine


name: PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 (Homo sapiens)


name: pro-SFTPC translocates from ER membrane to multivesicle body (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + 2 H2O => 2 a carboxylate + 2 H(+) + sn-glycero-3-phosphoethanolamine


name: (1S,2S)-pseudoephedrine + NAD(+) => (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: 2 H(+) + heme b => Fe(2+) + protoporphyrin IX


name: a ganglioside GA2 + H(+) + UDP => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-galactosamine


name: (E)-caffeoylpyruvate + H2O => (E)-caffeate + H(+) + pyruvate


name: Dephosphorylation of TYK2 by PTP1B (Gallus gallus)


name: guanosine(18) in tRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: STAT3-dependent DNMT1 gene expression (Homo sapiens)


name: SLC22A1 transports Cipro into hepatic cell (Gallus gallus)


name: (2S)-2-aminobutanoate + H2O + NAD(+) = 2-oxobutanoate + H(+) + NADH + NH4(+)


name: N-(4-oxobutylpyrrolinium) ion => 1-formylpyrrolizidine


name: Deubiquitination of RNF41 by P-USP8 (Drosophila melanogaster)


name: (R)-amygdalin + H2O <=> (R)-prunasin + D-glucose


name: RRAGA,B exchanges GDP for GTP (Drosophila melanogaster)


name: Frataxin transfers Fe2+ to ACO2 (Rattus norvegicus)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Rattus norvegicus)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GLI proteins bind CDC73 (Xenopus tropicalis)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Canis familiaris)


name: 2 Na(+)(out) + pyruvate(out) => 2 Na(+)(in) + pyruvate(in)


name: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Canis familiaris)


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O => 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + H(+) + phosphate


name: HLA-A specific activating MHC class I receptor activity


name: E2F6 binds the PRC1 complex (Drosophila melanogaster)


name: (E)-caffeoyl-CoA + putrescine <=> CoA + H(+) + N-caffeoylputrescine


name: H2O + isopenicillin N + phenylacetyl-CoA <=> CoA + H(+) + L-2-aminoadipate + penicillin G


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate => alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: ROS,RNS oxidize ACO2:4Fe-4S (Canis familiaris)


name: an oxidized polyvinyl alcohol + n H2O2 => a polyvinyl alcohol + n O2


name: Disassociation of Processive Complex and Completed Telomere End (Canis familiaris)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Mus musculus)


name: uridine(31) in tRNA <=> pseudouridine(31) in tRNA


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Sus scrofa)


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Bos taurus)


name: D-apionate + NAD(+) <=> 3-oxoisoapionate + H(+) + NADH


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + cholesterol => 1-hexadecanoyl-sn-glycero-3-phosphocholine + a cholesterol ester


name: an (R)-2-haloacid + H2O <=> a (2R)-2-hydroxycarboxylate + a halide anion + H(+)


name: (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + 2 glutathione <=> (17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + glutathione disulfide + H2O


name: ABC7, mABC1 and mABC2 mediate heme transport (Bos taurus)


name: H(+) + octanoate + octanoylglycerol => dioctanoylglycerol + H2O


name: Dephosphorylation of Gab1 by SHP2 (Gallus gallus)


name: H2O + thiamine <=> 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)


name: adenosine 3',5'-bisphosphate(out) + NAD(+)(in) <=> adenosine 3',5'-bisphosphate(in) + NAD(+)(out)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Sus scrofa)


name: 2-aminoprop-2-enoate + 2-methyl-3-sulfanylbutan-1-ol => S-(4-hydroxy-3-methylbutan-2-yl)-L-cysteine


name: guanosine(966) in 16S rRNA + S-adenosyl-L-methionine <=> H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine


name: 4-methyl-2-oxopentanoate + H(+) + NADH + NH4(+) => H2O + L-leucine + NAD(+)


name: deoxynucleotide transmembrane transporter activity


name: IL21:IL21R:JAK1 binds IL2RG:JAK3 (Homo sapiens)


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-GMP <=> GMP + H(+) + lactate


name: PARG dePARylates PARP1,PARP2 (Sus scrofa)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Homo sapiens)


name: L-serine + NAD(+) = 2-aminomalonate semialdehyde + H(+) + NADH


name: an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H2O <=> a thymidine in DNA + ADP-D-ribose


name: Autocatalytic phosphorylation of FGFR2b (Canis familiaris)


name: Inactive G alpha (q) reassociates with G beta:gamma (Sus scrofa)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Xenopus tropicalis)


name: PI3 binds the bacterial surface (Homo sapiens)


name: phosphatidylinositol 3-kinase activator activity


name: mitochondrial ATP-gated potassium channel activity


name: GSTO dimers reduce DeHA to AscH- (Mus musculus)


name: Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Rattus norvegicus)


name: (S)-3'-hydroxy-N-methylcoclaurine + S-adenosyl-L-methionine <=> (S)-reticuline + H(+) + S-adenosyl-L-homocysteine


name: H2O + N-(15Z-tetracosenoyl)-taurine = (15Z)-tetracosenoate + taurine


name: an (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Rattus norvegicus)


name: NOTCH1 associates with negative regulators NUMB and ITCH (Homo sapiens)


name: D-serine(in) + L-alanine(out) + Na(+)(out) <=> D-serine(out) + L-alanine(in) + Na(+)(in)


name: protein serine/threonine/tyrosine kinase activity


name: SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Sus scrofa)


name: BIRC(cIAP1/2) ubiquitinates RIPK1 (Rattus norvegicus)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Xenopus tropicalis)


name: Formation of MHC I:Nef Complex (Homo sapiens)


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Mus musculus)


name: Activated type I receptor phosphorylates SMAD2/3 directly (Sus scrofa)


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Plasmodium falciparum)


name: mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins (Mycobacterium tuberculosis)


name: PLA2G2A binds bacterial phospholipids (Xenopus tropicalis)


name: Mature NOTCH heterodimer traffics to the plasma membrane (Mus musculus)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Rattus norvegicus)


name: Discoidal HDL binds membrane-associated free cholesterol (Rattus norvegicus)


name: acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) => CO + CoA + methyl-Co(III)-[corrinoid Fe-S protein]


name: Hydrolysis of PIP3 to PI(3,4)P2 (Canis familiaris)


name: (R)-carnitine + decanoyl-CoA => CoA + O-decanoyl-(R)-carnitine


name: NIPAs transport Mg2+ from extracellular region to cytosol (Mus musculus)


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Caenorhabditis elegans)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Gallus gallus)


name: GP1b-IX-V binds 14-3-3-zeta (Homo sapiens)


name: The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Drosophila melanogaster)


name: PGH2 is isomerised to PGE2 by PTGES (Danio rerio)


name: PDK isozymes phosphorylate PDHC subunit E1 (Sus scrofa)


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Canis familiaris)


name: SPRY2 is serine phosphorylated in response to MAPK activation (Gallus gallus)


name: K63polyUb-TRAF6 ubiquitinates TAK1 (Homo sapiens)


name: acetaldehyde + H(+) + NADH + NH4(+) => ethylamine + H2O + NAD(+)


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Rattus norvegicus)


name: (2R)-O-phospho-3-sulfolactate = H(+) + phosphoenolpyruvate + sulfite


name: miR-20 microRNAs bind CNOT6L mRNA (Homo sapiens)


name: H(+)(in) + L-glutamate(in) = H(+)(out) + L-glutamate(out)


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 2 A + 3 H2O = [DsrC protein]-dithiol + 2 AH2 + 2 H(+) + sulfite


name: CASP9 is phosphorylated at T412 (Canis familiaris)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate => 2 Fe(III)-[cytochrome c] + L-gulono-1,4-lactone


name: 5-HT2 receptor can bind serotonin (Canis familiaris)


name: acetyl-CoA + docosanoyl-CoA = 3-oxotetracosanoyl-CoA + CoA


name: COQ2 ligates all-E-10PrP2 to PHB (Sus scrofa)


name: di-(9Z)-octadecenoylglycerol + H2O = (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+)


name: EHMT1,EHMT2 trimethylates lysine-16 of ATF7IP (Homo sapiens)


name: ATP + D-ribulose 5-phosphate <=> ADP + D-ribulose 1,5-bisphosphate + H(+)


name: di-trans,poly-cis-dolichol + NADP(+) => di-trans,cis-polyprenol + H(+) + NADPH


name: 2-methylhexadecanoate + ATP + CoA => 2-methylhexadecanoyl-CoA + AMP + diphosphate


name: "Hydron translocation or charge separation linked to oxidoreductase reactions"


name: 2 a thiol + L-cysteinyl-[sulfatase] + O2 <=> 3-oxo-L-alanyl-[sulfatase] + an organic disulfide + H(+) + H2O + hydrogen sulfide


name: CASP4, CASP5 cleave GSDMD (Gallus gallus)


name: AhpC reduces peroxidated lipids (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: D-aspartate + H2O + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate


name: CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl-[protein] + succinate => 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + O2


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3) = beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: a 1,2-diacyl-sn-glycerol + lipid A 1,4'-bis(2-aminoethyl diphosphate) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A hexaacyl 1-(2-aminoethyl diphosphate)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 = (8R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate


name: B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain (Rattus norvegicus)


name: 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Gallus gallus)


name: allocryptopine + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-cis-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase]


name: H(+)(in) + L-alanyl-L-valine(in) => H(+)(out) + L-alanyl-L-valine(out)


name: PA is converted to CDP-DAG by CDS1 (Rattus norvegicus)


name: Phosphorylation of LAT by p-SYK (Homo sapiens)


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)


name: AH2 + 2 aquacob(III)alamin => A + 2 cob(II)alamin + 2 H(+) + 2 H2O


name: oxidoreductase activity, acting on CH or CH2 groups


name: S-1-propenyl-L-cysteine sulfoxide = (E)-prop-1-en-1-SO-peroxol + 2-aminoprop-2-enoate


name: (4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O => 3-oxoadipate + H(+)


name: CD59 inhibits MAC formation (Sus scrofa)


name: Translocation of PMAIP1 (NOXA) to mitochondria (Bos taurus)


name: 3-iodo-L-tyrosine + iodide + NADP(+) => 3,5-diiodo-L-tyrosine + H(+) + NADPH


name: p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene (Homo sapiens)


name: adenosine 3',5'-bisphosphate + estrone 3-sulfate + H(+) => 3'-phosphoadenylyl sulfate + estrone


name: Association of  PARVA with TESK1 (Sus scrofa)


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Caenorhabditis elegans)


name: 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxylate + H(+) => 2,3,6,8,9-pentahydroxy-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracen-1-one + CO2


name: Activated NOD2 oligomerizes (Canis familiaris)


name: Disassociation of PLC-gamma1 from LAT (Mus musculus)


name: Autophosphorylation of LYN kinase (Gallus gallus)


name: D-serine(in) + L-glutamine(out) + Na(+)(out) <=> D-serine(out) + L-glutamine(in) + Na(+)(in)


name: TAB2 binds to ubiquitinated IAP2:BEN:UEV1A E3 ligase complex and activates TAK1 kinase (Drosophila melanogaster)


name: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO2


name: Fibrillin C-terminal processing (Canis familiaris)


name: Interaction of SHP-1 or SHP-2 with phospho PD-1 (Homo sapiens)


name: acetate + cytosine + H(+) => H2O + N(4)-acetylcytosine


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Canis familiaris)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Rattus norvegicus)


name: didemethylasterriquinone D + dimethylallyl diphosphate <=> asterriquinone C1 + diphosphate


name: CASP8 cleaves N4BP1 at D424, D490 (Gallus gallus)


name: (S)-malate(out) + 2-oxoglutarate(in) => (S)-malate(in) + 2-oxoglutarate(out)


name: acetyl-CoA + N-terminal L-methionyl-L-isoleucyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein]


name: FDPS dimer transfers IPPP to GPP (Caenorhabditis elegans)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2)


name: 2,5-dihydroxybenzoyl-CoA + H2O + NAD(+) => 2-hydroxybenzoyl-CoA + H(+) + NADH + O2


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Homo sapiens)


name: chlorophyllide b + 2 H2O + NADP(+) => 7(1)-hydroxychlorophyllide a + H(+) + NADPH + O2


name: ATR phosphorylates TP53 (Rattus norvegicus)


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: HSP70 binds to HSP40:nascent protein (Saccharomyces cerevisiae)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Homo sapiens)


name: Translocation of COP1 from the nucleus to the cytoplasm (Dictyostelium discoideum)


name: L-glutamine(in) + L-valine(out) + Na(+)(out) => L-glutamine(out) + L-valine(in) + Na(+)(in)


name: SUMOylation of BLM with SUMO2,3 (Xenopus tropicalis)


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP


name: ABCA4 mediates atRAL transport (Homo sapiens)


name: RHOB GAPs stimulate RHOB GTPase activity (Caenorhabditis elegans)


name: 3 S-adenosyl-L-methionine => 3 H(+) + nicotianamine + 3 S-methyl-5'-thioadenosine


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Danio rerio)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Homo sapiens)


name: Initial activation of proMMP2 by MMP14 (Sus scrofa)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate


name: G alpha (q) in G (q):RGS complex is inactivated (Saccharomyces cerevisiae)


name: FA anion flip-flops to the opposite surface (Canis familiaris)


name: SUCLG1/A2 cleaves succinyl-CoA (Canis familiaris)


name: Translocation of STAT1 dimer to nucleus (Sus scrofa)


name: PAOX:FAD oxidises NASPN to SPM (Caenorhabditis elegans)


name: MAP2K2 binds MAPK1 (Schizosaccharomyces pombe)


name: biphenyl-2,2',3-triol + H2O + NAD(+) => biphenyl-2,2'-diol + H(+) + NADH + O2


name: a 1-acyl-sn-glycero-3-phosphocholine + a cholesterol ester => a 1,2-diacyl-sn-glycero-3-phosphocholine + cholesterol


name: 4-hydroxybutanoate + ATP + CoA => 4-hydroxybutanoyl-CoA + AMP + diphosphate


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H(+) + NADPH => CDP-alpha-D-abequose + NADP(+)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Schizosaccharomyces pombe)


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Bos taurus)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Danio rerio)


name: ATP + gamma-L-glutamyl-L-cysteine + glycine <=> ADP + glutathione + H(+) + phosphate


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Rattus norvegicus)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Bos taurus)


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Dictyostelium discoideum)


name: TXLNA (IL14) binds syntaxin4 (Mus musculus)


name: (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[C-phycocyanin alpha-subunit] => phycocyanobilin-L-cysteinyl(84)-[C-phycocyanin alpha-subunit]


name: a very-long-chain (3R)-3-hydroxyacyl-CoA => a very-long-chain (2E)-enoyl-CoA + H2O


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Gallus gallus)


name: a hydroperoxyeicosatetraenoate => an oxoeicosatetraenoate + H2O


name: 2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)


name: Aquaporin-3 passively transports water out of cell (Rattus norvegicus)


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Mus musculus)


name: TNF-α:TNFR1 binds NSMAF (Xenopus tropicalis)


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Mus musculus)


name: 2 glutathione + L,L-homocystine <=> glutathione disulfide + 2 L-homocysteine


name: 2 a Fe(II)-siderophore + H(+) + NAD(+) = 2 a Fe(III)-siderophore + NADH


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Canis familiaris)


name: CARKD dehydrates S-NAD(P)HX to NADPH (Danio rerio)


name: RASA1 stimulates RAS GTPase activity (Xenopus tropicalis)


name: arginine + H2O => ornithine + urea [ARG2] (Canis familiaris)


name: Free APC/C phosphorylated by Plk1 (Mus musculus)


name: FPGS-2 transforms THF to THFPG (Caenorhabditis elegans)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Mus musculus)


name: ABP1 binds SHANK proteins (Rattus norvegicus)


name: beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Drosophila melanogaster)


name: Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 (Sus scrofa)


name: RHOA GAPs stimulate RHOA GTPase activity (Bos taurus)


name: PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Rattus norvegicus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + lathosterol + O2 = 7-dehydrocholesterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (Homo sapiens)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose <=> a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)


name: N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1248) in human 18S rRNA + S-methyl-5'-thioadenosine


name: Small molecule inhibitor binds RIPK1, RIPK3 (Canis familiaris)


name: GLA hydrolyzes PSAP(195-273):Gb3Cer:PE (Mus musculus)


name: (3S)-hydroxytetradecanoyl-CoA + H2O <=> (3S)-hydroxytetradecanoate + CoA + H(+)


name: PGH2 is degraded to 12S-HHT and MDA by TBXAS1 (Sus scrofa)


name: glycerol + phosphate => H2O + sn-glycerol 1-phosphate


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Schizosaccharomyces pombe)


name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate (Sus scrofa)


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Saccharomyces cerevisiae)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Homo sapiens)


name: (7S,17S)-dihydroperoxy-(4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoate => (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Homo sapiens)


name: Necl-2:Nectin 3 trans heterodimer interaction (Homo sapiens)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Canis familiaris)


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Bos taurus)


name: SLC6A15-mediated amino acid uptake (Danio rerio)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O = (17E)-cheilanthenediol


name: (3R)-3-[(carboxymethyl)amino]butanoate + 2 2-oxoglutarate + 2 O2 => (3R)-3-isocyanylbutanoate + 3 CO2 + 2 H2O + 2 succinate


name: 5,6,7,8-tetrahydromethanopterin + formaldehyde <=> 5,10-methylenetetrahydromethanopterin + H2O


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Caenorhabditis elegans)


name: an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H2O => an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-cysteinylglycine + L-glutamate


name: gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity


name: (9R,10S)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-(9R,10S)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: OPLAH hydrolyses OPRO to L-Glu (Rattus norvegicus)


name: SPP1 (osteopontin) binds integrins alphaVbeta1, alphaVbeta3, alphaVbeta5 (Homo sapiens)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NAD(+) <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH


name: PHF8 demethylates histone H4K20me1 (Canis familiaris)


name: Dissociation of insulin from insulin receptor (Rattus norvegicus)


name: L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Danio rerio)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] <=> 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: WLS dissociates from retromer (Mus musculus)


name: a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA = (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)


name: cyclohexane-1-carbonyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = cyclohex-1-ene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]


name: "cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein)"


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin <=> 2-hydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: hydroxyurea + O-acetyl-L-serine <=> acetate + H(+) + O-ureido-L-serine


name: 3',5'-cyclic GMP(in) => 3',5'-cyclic GMP(out)


name: Collagen type III degradation by MMP1,8,9,13 (Gallus gallus)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Gallus gallus)


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Homo sapiens)


name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)


name: myricetin + S-adenosyl-L-methionine = 7-O-methylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: Association of Cks1 with SCF(Skp2) complex (Caenorhabditis elegans)


name: D-galactose + NAD(+) <=> D-galactono-1,4-lactone + H(+) + NADH


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: beta-D-Delta(4)-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O = 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc


name: 3 H(+) + 3 NADPH + 3 O2 + probetaenone I => betaenone B + 3 H2O + 3 NADP(+)


name: H(+) + indole-3-pyruvate = CO2 + indole-3-acetaldehyde


name: (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) => H(+) + NADH + O2 + p-cumate


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Canis familiaris)


name: Autophosphorylation of PDGF beta receptors (Sus scrofa)


name: H(+) + NADH + 2 NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] => NAD(+) + 2 NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: HHAT palmitoylates Hh N-terminal fragment (Sus scrofa)


name: an acyl-CoA + H(+) + malonyl-CoA = a 3-oxoacyl-CoA + CO2 + CoA


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Canis familiaris)


name: H(+) + ilicicolin A epoxide + NADPH + O2 => 16-hydroxy-ilicicolin A epoxide + H2O + NADP(+)


name: Beta-catenin translocates to the nucleus (Danio rerio)


name: cladofulvin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 2 nataloe emodin + O2 + reduced [NADPH--hemoprotein reductase]


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Canis familiaris)


name: G/T mismatch-specific thymine-DNA glycosylase activity


name: PIN1 binds p-S345-NCF1 (Xenopus tropicalis)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Drosophila melanogaster)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate <=> (+)-thujopsene + diphosphate


name: Activation and association of ATM kinase at the DNA damage sites (Gallus gallus)


name: 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + H(+) + 2 H2O = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4(+)


name: GGA3 associates with activated MET receptor (Bos taurus)


name: Dephosphorylation of p107 (RBL1) by PP2A (Canis familiaris)


name: Interaction of Nectins with Afadin (Gallus gallus)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Xenopus tropicalis)


name: a [peptide](out) + ATP + H2O <=> a [peptide](in) + ADP + H(+) + phosphate


name: a triacylglycerol + H2O <=> a 1,3-diacylglycerol + a fatty acid + H(+)


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Bos taurus)


name: Cross-linking of FCGRIIA with IgG-coated Ag (Bos taurus)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Schizosaccharomyces pombe)


name: chloride + glycolate + H(+) => chloroacetate + H2O


name: (2E,6E)-farnesyl diphosphate + H2O => diphosphate + patchoulol


name: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose <=> a neolactoside IV(3)-alpha-NeuNAc,III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H(+) + O2 <=> aureusidin 6-O-beta-glucoside + H2O


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Xenopus tropicalis)


name: an L-alpha-amino acid + H2O + O2 => a 2-oxocarboxylate + H2O2 + NH4(+)


name: a 1,2-diacyl-sn-glycerol + N-tetracosanoylsphinganine-(1D-myo-inositol) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-tetracosanoylsphinganine


name: Budding of COPII coated vesicle (Sus scrofa)


name: a (Z)-N-(sulfonatooxy)alkenimidothioate <=> an epithionitrile + sulfate


name: an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose <=> an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+)


name: 2-oxoglutarate + N(6)-acetyl-L-lysine = 6-acetamido-2-oxohexanoate + L-glutamate


name: SRXN1 reduces hyperoxidized PRDX1 dimer (Rattus norvegicus)


name: 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H(+)


name: acetyl-CoA + L-methionine => CoA + H(+) + N(alpha)-acetyl-L-methionine


name: BLT receptors can bind LTB4 (Bos taurus)


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Rattus norvegicus)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Sus scrofa)


name: a 2'-unsubstituted isoflavone + O2 + reduced [NADPH--hemoprotein reductase] <=> a 2'-hydroxyisoflavone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated JNKs phosphorylate c-JUN (Danio rerio)


name: Protein P tetramer binds protein L (Homo sapiens)


name: nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Canis familiaris)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Homo sapiens)


name: PDPK1 phosphorylates SGK1 (Canis familiaris)


name: ZNF423 recruits NuRD to EBF2 target genes (Homo sapiens)


name: NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP (Bos taurus)


name: SHP-1 and SHP-2 bind pBTLA (Rattus norvegicus)


name: snRNA Cap hypermethylation (Canis familiaris)


name: nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs (Homo sapiens)


name: (13E)-labda-7,13-dien-15-ol + diphosphate => geranylgeranyl diphosphate + H2O


name: Active FLT3 binds to ABL2 (Homo sapiens)


name: (S)-codamine + H(+) + S-adenosyl-L-homocysteine => (S)-reticuline + S-adenosyl-L-methionine


name: TBC1D7 binds the TSC1-TSC2 complex (Homo sapiens)


name: M6PR transports activated ARSA to the lysosome (Rattus norvegicus)


name: a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine


name: [thioredoxin]-disulfide + H2O + L-methionyl-[protein] <=> [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]


name: mandelate + O2 = H2O2 + phenylglyoxylate


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 (Dictyostelium discoideum)


name: D-maltotriono-1,5-lactone + H2O2 => D-maltotriose + O2


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Mus musculus)


name: Phosphorylation of LIMK-1 by PAK (Xenopus tropicalis)


name: a 2'-deoxyribonucleoside 5'-phosphate + 2 H(+) + 2 phosphate => a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O


name: 8-amino-8-demethylriboflavin + S-adenosyl-L-methionine <=> 8-demethyl-8-(methylamino)riboflavin + H(+) + S-adenosyl-L-homocysteine


name: a ribonucleoside 5'-diphosphate + ATP => a ribonucleoside 5'-triphosphate + ADP


name: a 3'-end 3'-phospho-ribonucleotide-RNA + GTP = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + diphosphate + GMP


name: "RNA 3'-terminal-phosphate cyclase (GTP)"


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + ADP + H(+) => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + ATP


name: L-threonine(in) + Na(+)(in) <=> L-threonine(out) + Na(+)(out)


name: LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)


name: dAMP(out) + phosphate(in) = dAMP(in) + phosphate(out)


name: dhurrin + H(+) + UDP => (S)-4-hydroxymandelonitrile + UDP-alpha-D-glucose


name: a [peptide]-C-terminal (2S)-2-hydroxyglycine = a [peptide]-C-terminal amide + glyoxylate


name: MECP2:CREB1 binds SST gene promoter (Homo sapiens)


name: ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Schizosaccharomyces pombe)


name: TTR:RBP:atROL binds to STRA6 receptor (Gallus gallus)


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Gallus gallus)


name: SMPD1 hydrolyzes SPHM (Caenorhabditis elegans)


name: MBTPS1 (S1P) cleaves CREB3L3 (Gallus gallus)


name: Phosphorylation of pPTK2 by SRC (Mus musculus)


name: N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-taurine => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2


name: Recruitment of SYK to phosphorylated ITAMs (Bos taurus)


name: (S)-scoulerine + H(+) + H2O2 => (S)-reticuline + O2


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Bos taurus)


name: odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 (Homo sapiens)


name: AMP + ATP <=> ADP + ADP [AK2] (Bos taurus)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Drosophila melanogaster)


name: Active ARF recruits coatomer (Mus musculus)


name: CES1,CES2 hydrolyze ASA- to ST (Danio rerio)


name: FLVCR1-1 transports heme from cytosol to extracellular region (Gallus gallus)


name: Assembly of hexameric IL-6 receptor (Xenopus tropicalis)


name: TLE tetramers bind TCF/LEF at WNT promoters (Canis familiaris)


name: cholate + UDP-alpha-D-glucuronate <=> choloyl-24-O-(beta-D-glucuronate) + UDP


name: ESPL1 (Separase) cleaves centromeric cohesin (Homo sapiens)


name: 3 Na(+)(out) + thiosulfate(out) = 3 Na(+)(in) + thiosulfate(in)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Danio rerio)


name: Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA (Drosophila melanogaster)


name: p-S MAPK6 phosphorylates NCOA3 (Xenopus tropicalis)


name: N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine => H(+) + phosphocholine + S-adenosyl-L-homocysteine


name: dTDP-6-deoxy-beta-L-talose + NAD(+) <=> dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADH


name: Formation of Elongin complex (Drosophila melanogaster)


name: H(+) + N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine => N-methylethanolamine phosphate + S-adenosyl-L-methionine


name: L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-methionine = 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-homocysteine


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Rattus norvegicus)


name: 3-(methylsulfanyl)acryloyl-CoA + 2 H2O <=> acetaldehyde + CO2 + CoA + methanethiol


name: L-glutamate(out) + N-acetyl-L-cysteine(in) => L-glutamate(in) + N-acetyl-L-cysteine(out)


name: AVPR1A,2 bind AVPR antagonists (Rattus norvegicus)


name: catechol + H(+) + NADH => cis-1,2-dihydrobenzene-1,2-diol + NAD(+)


name: MLCL is acylated to CL by LCLAT1 (ER) (Danio rerio)


name: ACVRL1 binds BMP9,BMP10 (Rattus norvegicus)


name: Formation of Pol zeta complex (Sus scrofa)


name: 6-hydroxyhexan-6-olide = 6-oxohexanoate + H(+)


name: Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Canis familiaris)


name: adenosine 5'-phosphosulfate + H2O = AMP + 2 H(+) + sulfate


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Caenorhabditis elegans)


name: PLK1 phosphorylates FIRRM at S43 (Danio rerio)


name: a fatty acid + CoA + H(+) => a fatty acyl-CoA + H2O


name: 15-hydroxypentadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA => 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: D-histidine(in) + H(+)(in) + L-ornithine(out) => D-histidine(out) + H(+)(out) + L-ornithine(in)


name: Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)


name: Sulfite is oxidized to sulfate (Sus scrofa)


name: ATPase-coupled monoatomic cation transmembrane transporter activity


name: LCAT:spherical HDL complex <=> LCAT + spherical HDL (Gallus gallus)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate => 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + NADP(+) + phosphate = [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + H(+) + NADPH


name: "[amino-group carrier protein]-5-phospho-L-glutamate reductase"


name: GPCR neuropeptide receptor binds neuropeptides B and W (Bos taurus)


name: 1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: Cross-linking of FCGRIIA with IgG-coated Ag (Homo sapiens)


name: p-T774-PKN1 phosphorylates PPP1R14A (Bos taurus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Sus scrofa)


name: chloride(out) + Cs(+)(in) + 2 hydrogencarbonate(in) = chloride(in) + Cs(+)(out) + 2 hydrogencarbonate(out)


name: 8-desmethylnovobiocic acid + S-adenosyl-L-methionine = H(+) + novobiocic acid + S-adenosyl-L-homocysteine


name: a 2-oxocarboxylate + H(+) = an aldehyde + CO2


name: (9Z,12Z)-octadecadienoate + AH2 + O2 => (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O


name: Removal of remaining Flap (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O = (3S,6E)-nerolidol + diphosphate


name: Activated FGFR3 binds PLCG1 (Drosophila melanogaster)


name: FGFR4 binds HS:KLB:FGF19 (Xenopus tropicalis)


name: TLR9 processing at neutral pH (Sus scrofa)


name: a flavonol 3-O-beta-D-glucoside + malonyl-CoA => a flavonol 3-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Rattus norvegicus)


name: ME1 tetramer decarboxylates OA to PYR (Drosophila melanogaster)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Caenorhabditis elegans)


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Danio rerio)


name: GTP + L-glutamate + oxidized coenzyme F420-0 <=> GDP + H(+) + oxidized coenzyme F420-1 + phosphate


name: nocardicin E + S-adenosyl-L-methionine = H(+) + isonocardicin A + S-methyl-5'-thioadenosine


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Mus musculus)


name: prostaglandin F2alpha(out) = prostaglandin F2alpha(in)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Bos taurus)


name: JAG1 gene expression is inhibited by RUNX3 (Homo sapiens)


name: butan-1-ol + propanoyl-CoA => butyl propanoate + CoA


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> diphosphate + fusoxypene B


name: a (2E)-enoyl-[ACP] + H2O => a (3R)-hydroxyacyl-[ACP]


name: adenosine 3',5'-bisphosphate + H(+) + thyroxine sulfate => 3'-phosphoadenylyl sulfate + thyroxine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: H(+) + H2O + juvenile hormone III + oxidized [NADPH--hemoprotein reductase] => methyl (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase]


name: ATM phosphorylates TTC5 (Dictyostelium discoideum)


name: (2S)-2-amino-4-deoxychorismate + FMN = 3-(1-carboxyvinyloxy)anthranilate + FMNH2


name: FDPS dimer transfers IPPP to GPP (Schizosaccharomyces pombe)


name: anhydrotetracycline + H(+) + NADPH + O2 <=> 5a,11a-dehydrotetracycline + H2O + NADP(+)


name: aclacinomycin T + dTDP-2-deoxy-beta-L-fucose => aclacinomycin S + dTDP + H(+)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Danio rerio)


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Mus musculus)


name: alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose = [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + H(+) + UDP


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine => a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine


name: CYTH proteins stimulate ARF1 GTPase activity (Saccharomyces cerevisiae)


name: guanidinoacetate + H2O => glycine + urea


name: LDL + LDLR => LDL:LDLR complex (Homo sapiens)


name: RAS proteins are depalmitoylated (Gallus gallus)


name: Fibulin binds elastic fibres (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> delta-araneosene + diphosphate


name: 1-octadecanoyl-2-(15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+)


name: H(+) + L-glutamyl 5-phosphate + NADPH => L-glutamate 5-semialdehyde + NADP(+) + phosphate


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Dictyostelium discoideum)


name: ATP + holo-[peptidyl-carrier protein] + L-proline <=> AMP + diphosphate + L-prolyl-[peptidyl-carrier protein]


name: Lactoperoxidase (LPO) produces OSCN- (Rattus norvegicus)


name: RAC3 binds effectors at the plasma membrane (Drosophila melanogaster)


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Rattus norvegicus)


name: 3 H(+) + NADPH + O2 + 2 rubrofusarin B <=> 2 H2O + NADP(+) + nigerone


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + hexadecanoyl-CoA => 1-O-hexadecyl-2-acetyl-3-hexadecanoyl-sn-glycerol + CoA


name: Laminins bind galactosyl sulfatide and related sulfated glycolipids (Homo sapiens)


name: Dephosphorylation of EPSP yields chorismate (Mycobacterium tuberculosis)


name: (20S)-ginsenoside Rd + UDP-alpha-D-glucose = (20S)-ginsenoside Rb1 + H(+) + UDP


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 => prostaglandin G2


name: (25S)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => (25S)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: CYP26C1 4-hydroxylates 9cRA (Homo sapiens)


name: D-glucose(out) + N(pros)-phospho-L-histidyl-[protein] = D-glucose 6-phosphate(in) + L-histidyl-[protein]


name: 3 H(+) + H2O + urea-1-carboxylate <=> 2 CO2 + 2 NH4(+)


name: RANBP2 SUMOylates MDM2 with SUMO1 (Sus scrofa)


name: a 27-hydroxysterol + UDP-alpha-D-glucose => a sterol 27-beta-D-glucoside + H(+) + UDP


name: ADK phosphorylates RBV (Dictyostelium discoideum)


name: C3 convertases spontaneously dissociate (Canis familiaris)


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Mus musculus)


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione <=> (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O


name: MEN1 binds MLL1 complex (Drosophila melanogaster)


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Mus musculus)


name: desmethylnectriapyrone + S-adenosyl-L-methionine => H(+) + nectriapyrone + S-adenosyl-L-homocysteine


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Sus scrofa)


name: cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate <=> (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Homo sapiens)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Xenopus tropicalis)


name: S-methyl-1-thiol-D-ribulose 5-phosphate => S-methyl-5-thio-D-ribulose 1-phosphate


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CMP + H(+) => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Canis familiaris)


name: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate


name: 2-(hydroxyimino)propanoate + acetone <=> acetone oxime + pyruvate


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Canis familiaris)


name: uridine(2605) in 23S rRNA = pseudouridine(2605) in 23S rRNA


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Saccharomyces cerevisiae)


name: 1,4-dihydroxy-2-naphthoate + all-trans-dodecaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-12 + CO2 + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate


name: BTNL8 binds resting T cell surface (Xenopus tropicalis)


name: Autocatalytic phosphorylation of FGFR1b (Mus musculus)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Caenorhabditis elegans)


name: CaMKII binds activated NMDA receptor (Homo sapiens)


name: (9Z)-hexadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: SHP1 and SHP2 bind the common beta chain (Mus musculus)


name: Activated FMNL3 binds G-actin (Mus musculus)


name: CHRM1,3,5 bind acetylcholine (Rattus norvegicus)


name: L-cystine(out) + L-glutamate(in) = L-cystine(in) + L-glutamate(out)


name: ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE (Danio rerio)


name: inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ (Gallus gallus)


name: (S)-methioninol + H2O + NAD(+) <=> 1-hydroxy-4-(methythio)butan-2-one + H(+) + NADH + NH4(+)


name: 2-oxoglutarate + [2-(trimethylamino)ethyl]phosphonate + O2 = [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + CO2 + succinate


name: histone H3K36 methyltransferase activity


name: ATXN3 deubiquitinates polyUb-PARK2 (Rattus norvegicus)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Bos taurus)


name: USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Saccharomyces cerevisiae)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA = 3-oxochol-4,6-dien-24-oyl-CoA + H2O


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Mus musculus)


name: (11Z)-3-oxoicosenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(11Z)-eicosenoyl-CoA + NADP(+)


name: PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Drosophila melanogaster)


name: H(+)(in) + uridine(in) <=> H(+)(out) + uridine(out)


name: H(+)(out) + L-alanyl-L-leucyl-L-alanine(out) = H(+)(in) + L-alanyl-L-leucyl-L-alanine(in)


name: (5'S,6'R)-C-glycyluridine + O2 = CO2 + H2O + uridine-5'-carboxamide


name: adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O + 4 L-glutamine = adenosylcob(III)yrate + 4 ADP + 4 H(+) + 4 L-glutamate + 4 phosphate


name: "adenosylcobyric acid synthase (glutamine-hydrolyzing)"


name: (S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) <=> ATP + H(+) + L-2-aminoadipate + NADPH


name: adenosine(4) in tRNA(His) + S-adenosyl-L-methionine => 2'-O-methyladenosine(4) in tRNA(His) + H(+) + S-adenosyl-L-homocysteine


name: cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Canis familiaris)


name: holo-[cytochrome c] => apo-[cytochrome c] + heme b


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Saccharomyces cerevisiae)


name: H2O + L-seryl-tRNA(Thr) <=> L-serine + tRNA(Thr)


name: 23,24-dihydrocucurbitacin B + NAD(+) = cucurbitacin B + H(+) + NADH


name: H2O + hypoxanthine + NAD(+) <=> H(+) + NADH + xanthine


name: Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: CNRs bind CNR agonists (Rattus norvegicus)


name: deoxycholoyl-CoA + ursodeoxycholate <=> deoxycholate + ursodeoxycholoyl-CoA


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Homo sapiens)


name: isopropylmalate transmembrane transporter activity


name: paromamine + UDP-alpha-D-kanosamine => H(+) + kanamycin C + UDP


name: 17-(4-hydroxyphenyl)heptadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] = 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: cholesterol + H(+) + NADPH + O2 => 26-hydroxycholesterol + H2O + NADP(+)


name: SLC2A5 transports fructose from extracellular region to cytosol (Saccharomyces cerevisiae)


name: TIRAP binds PIP2-rich regions in the plasma membrane (Sus scrofa)


name: a long-chain fatty acid + H(+) + hnu = a long-chain alkane + CO2


name: (20S)-ginsenoside F1 + UDP-alpha-D-glucose = (20S)-ginsenoside Rg1 + H(+) + UDP


name: alpha-pinene oxide <=> (Z)-2-methyl-5-isopropylhexa-2,5-dienal


name: DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)


name: Hikeshi binds HSP70s:ATP (Dictyostelium discoideum)


name: Phosphorylated PKN1 binds androgen receptor (AR) (Rattus norvegicus)


name: 4-hydroxybenzoate + 2 H(+) + NADPH => 4-hydroxybenzaldehyde + H2O + NADP(+)


name: MYLK (MLCK) Active Calmodulin Binding (Bos taurus)


name: Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Bos taurus)


name: ABHD4 hydrolyses NAPE (Canis familiaris)


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Mus musculus)


name: ATP + L-arabinose <=> ADP + beta-L-arabinose 1-phosphate + H(+)


name: SUMOylation of UBE2I with SUMO1 (Dictyostelium discoideum)


name: NMRK1 phosphorylates NR to yield NMN (Drosophila melanogaster)


name: cis-aconitate(in) + citrate(out) = cis-aconitate(out) + citrate(in)


name: 8-oxo-dADP + H2O <=> 8-oxo-dAMP + H(+) + phosphate


name: 6-oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O <=> 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)


name: (3S)-hydroxytetradecanoyl-CoA + H2O = (3S)-hydroxytetradecanoate + CoA + H(+)


name: (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2


name: ADRM1:26S proteaseome binds USP14 (Saccharomyces cerevisiae)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Rattus norvegicus)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Sus scrofa)


name: H2O + L-alanyl-tRNA(Thr) => H(+) + L-alanine + tRNA(Thr)


name: ent-kaur-16-en-19-al + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-kaur-16-en-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 Na(+)(in) + tauroallocholate(in) => 2 Na(+)(out) + tauroallocholate(out)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: CDK4 inhibitors bind CDK4 (Homo sapiens)


name: Active MTORC1 phosphorylates ULK1 (Canis familiaris)


name: MIB2 ubiquitinates CFLAR  (Drosophila melanogaster)


name: Association of Emi1 with Cdh1 (Drosophila melanogaster)


name: COX10 transforms heme to heme O (Homo sapiens)


name: (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate <=> 5-methylsulfinylpentyl nitrile + sulfate + sulfur


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Homo sapiens)


name: (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2


name: TCF:Beta-catenin binds SOX proteins (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ethanolamine => (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl) ethanolamine + H2O


name: RHOB GEFs activate RHOB (Caenorhabditis elegans)


name: 1D-myo-inositol 2,5-bisphosphate + H2O <=> 1D-myo-inositol 2-phosphate + phosphate


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Caenorhabditis elegans)


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Rattus norvegicus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Rattus norvegicus)


name: Oxidative demethylation of 3-meC damaged DNA by ALKBH2 (Homo sapiens)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Rattus norvegicus)


name: 6-deoxocastasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> castasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: G-protein alpha subunit is inactivated (Drosophila melanogaster)


name: 13,14-dihydro-15-oxo-prostaglandin E2 + NADP(+) = 15-oxoprostaglandin E2 + H(+) + NADPH


name: glyoxylate + L-serine => 3-hydroxypyruvate + glycine


name: Endosomal TLRs pass through the Golgi (Xenopus tropicalis)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Gallus gallus)


name: IL37, IL37(?-218) binds IL18BP (Bos taurus)


name: GSDME (1-270) binds PIPs (Rattus norvegicus)


name: 3 (R)-methylmalonyl-CoA + 9 H(+) + long-chain fatty acyl-[mycocerosate synthase] + 6 NADPH = 3 CO2 + 3 CoA + 3 H2O + 6 NADP(+) + trimethylated-mycocerosoyl-[mycocerosate synthase]


name: glycine betaine + 3 H(+) + 3 S-adenosyl-L-homocysteine => glycine + 3 S-adenosyl-L-methionine


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Homo sapiens)


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Sus scrofa)


name: H2O + L-fucono-1,4-lactone <=> H(+) + L-fuconate


name: (+)-artemisinic alcohol + O2 + reduced [NADPH--hemoprotein reductase] = (+)-artemisinic aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: ARL1 recruits TGN Golgin homodimers (Caenorhabditis elegans)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Mus musculus)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Caenorhabditis elegans)


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Bos taurus)


name: Superoxide reduces cytochrome c (Gallus gallus)


name: IL4I1:FAD oxidises L-Phe to kPPV (Plasmodium falciparum)


name: (2R)-3-phosphoglycerate + ATP <=> (2R)-3-phospho-glyceroyl phosphate + ADP


name: (4S)-4-hydroxy-2-oxoheptanedioate => (4Z)-2-oxohept-4-enedioate + H2O


name: an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + GDP-alpha-D-mannose <=> GDP + H(+) + mannosylinositol phosphorylphytoceramide


name: 1-hexadecanoyl-sn-glycero-3-phosphate + ethanolamine + H(+) => 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O


name: 2-thiocytidine 5'-phosphate + ADP + H(+) => 2-thiocytidine + ATP


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Drosophila melanogaster)


name: (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H(+) => (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Gallus gallus)


name: (9Z)-hexadecenoate + ethanol + H(+) => ethyl (9Z)-hexadecenoate + H2O


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)


name: D-arabinose 5-phosphate => D-glyceraldehyde 3-phosphate + glycolaldehyde


name: SLC45A3 transports Glc from extracellular region to cytosol (Homo sapiens)


name: solasodine + UDP-alpha-D-glucose <=> H(+) + solasodine 3-beta-D-glucoside + UDP


name: (2E)-but-2-enal + hydrogen cyanide => (2S,3E)-2-hydroxypent-3-enenitrile


name: D-ribitol 5-phosphate + NAD(+) => D-ribulose 5-phosphate + H(+) + NADH


name: aliphatic (S)-hydroxynitrile lyase activity


name: ATXN3 binds polyUb-PARK2 (Canis familiaris)


name: chloride(in) + L-isoleucine(in) + 2 Na(+)(in) => chloride(out) + L-isoleucine(out) + 2 Na(+)(out)


name: 2 a 2-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: 3 hydrogencarbonate(out) + Na(+)(out) = 3 hydrogencarbonate(in) + Na(+)(in)


name: NPM1-ALK- and p-STAT3-dependent IRF4 gene expression (Homo sapiens)


name: ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE (Rattus norvegicus)


name: ATP + L-threonine <=> diphosphate + L-threonyl-5'-AMP


name: ROCK1,ROCK2 are activated (Canis familiaris)


name: Caspase 3-mediated cleavage of PKC delta (Gallus gallus)


name: n 3'-phosphoadenylyl sulfate + dermatan 4'-sulfate <=> n adenosine 3',5'-bisphosphate + dermatan 4',6'-bissulfate + n H(+)


name: NAD(+) + pyridoxine = H(+) + NADH + pyridoxal


name: Phosphorylated Emi1 binds the beta-TrCP in the SCF complex (Homo sapiens)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Mus musculus)


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Rattus norvegicus)


name: GATA4, SMAD1:SMAD4, MEF2C, TBX20, and NKX2-5 bind the NKX2-5 gene (Homo sapiens)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)


name: MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB (Rattus norvegicus)


name: H(+) + 2 malonyl-CoA + nicotinyl-CoA = 4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one + 2 CO2 + 3 CoA


name: PSIP1 binds MEN1 associated with MLL2 complex (Mus musculus)


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Sus scrofa)


name: STAT4 binds p-Y-IL23R in IL23:IL23 receptor (Canis familiaris)


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Xenopus tropicalis)


name: Aquaporin-1 passively transports water out of cell (Canis familiaris)


name: Expression of MESP1 in cardiogenesis (Homo sapiens)


name: (2E,4Z)-2-chloromuconate + 2 H(+) => 3-chlorocatechol + O2


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Mus musculus)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Homo sapiens)


name: N-hydroxylation of 4-aminobiphenyl (Homo sapiens)


name: Activation of conventional Protein Kinase C (Schizosaccharomyces pombe)


name: Phosphorylation of cPLA2 by ERK-2 (Mus musculus)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Rattus norvegicus)


name: (E)-2-benzylidenesuccinyl-CoA + H2O => (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA


name: guaiacol + O2 + reduced [NADH--hemoprotein reductase] = catechol + formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: PTGS2 dimer binds PTGS2 inhibitors (Bos taurus)


name: nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical  HDL + chylomicron (Rattus norvegicus)


name: 9beta-pimara-7,15-dien-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-dien-19-al + O2 + reduced [NADPH--hemoprotein reductase]


name: Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)


name: AH2 + L-cysteine + Mo-molybdopterin <=> A + H2O + L-alanine + thio-Mo-molybdopterin


name: acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose => CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + H(+)


name: trans-4-hydroxy-L-proline + ubiquinone-10 = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H(+) + ubiquinol-10


name: AH2 + barbiturate + H(+) => A + H2O + uracil


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Canis familiaris)


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Homo sapiens)


name: estrone + H(+) + NADPH => 17beta-estradiol + NADP(+)


name: PIAS1,4 SUMOylates BRCA1 with SUMO2,3 (Homo sapiens)


name: 2-amino-2-deoxy-D-gluconate(out) + N(pros)-phospho-L-histidyl-[protein] = 2-amino-2-deoxy-D-gluconate 6-phosphate(in) + L-histidyl-[protein]


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => diphosphate + fusoxypene C


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Drosophila melanogaster)


name: RHOB GEFs activate RHOB (Drosophila melanogaster)


name: PSAP(195-273) dimer binds PE (Homo sapiens)


name: H2O + isopimara-7,15-dienal + NADP(+) <=> 2 H(+) + isopimarate + NADPH


name: (S)-piperazine-2-carboxamide + H2O <=> (S)-piperazine-2-carboxylate + NH4(+)


name: Autocatalytic activation of MMP7 (Bos taurus)


name: TBC1D25 (OATL1) binds ATG8 homologues (Canis familiaris)


name: CYP19A1 hydroxylates TEST to EST17b (Drosophila melanogaster)


name: (9Z)-octadecenoate + 2-(9Z,12Z-octadecadienoyl)-glycerol + H(+) => 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O


name: SIRT1 deacetylates HINT1 dimer (Canis familiaris)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADH = all-trans-lycopaoctaene + 2 diphosphate + NAD(+)


name: LIPC dimer binds heparin (Xenopus tropicalis)


name: WNT5A binds FZD and ROR receptors (Bos taurus)


name: a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Bos taurus)


name: uridylyl-uridylyl-ribonucleotide-RNA <=> a 3'-end uridylyl-2',3'-cyclophospho-uridine-RNA + a 5'-end dephospho-ribonucleoside-RNA


name: CHRM2 binds CHRM2 antagonists (Mus musculus)


name: glutathione(in) + taurocholate(out) <=> glutathione(out) + taurocholate(in)


name: cis-abienol + diphosphate => 8-hydroxycopalyl diphosphate


name: H2O + N-(dodecanoyl)-sphinganine = dodecanoate + sphinganine


name: H2O + N(tele)-phospho-L-histidyl-[protein] <=> L-histidyl-[protein] + phosphate


name: PTEN undergoes monoubiquitination (Homo sapiens)


name: H2O + L-isoleucine-(+)-12-hydroxy-7-isojasmonate = L-isoleucine + tuberonate


name: guanosine(in) + H(+)(in) => guanosine(out) + H(+)(out)


name: p-PKR dimer phosphorylates CDK1 (Canis familiaris)


name: 4-hydroxybenzoate + UDP-alpha-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP


name: H2O + O2 + pyridoxamine 5'-phosphate => H2O2 + NH4(+) + pyridoxal 5'-phosphate


name: LTA4 is converted to EXA4 by ALOX15 (Homo sapiens)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Drosophila melanogaster)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Drosophila melanogaster)


name: EXA4 is converted to EXC4 by LTC4S (Homo sapiens)


name: ATM binds PEX5 (Drosophila melanogaster)


name: Delta(1)-dihydrotestosterone + H2O => 1,17beta-dihydroxyandrostan-3-one


name: a ribonucleoside 3',5'-bisphosphate + H2O <=> a ribonucleoside 5'-phosphate + phosphate


name: 2,6,10,14-tetramethylpentadecanoate + ATP + CoA => AMP + diphosphate + pristanoyl-CoA


name: (4Z)-2-oxohept-4-enedioate + CO2 => (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+)


name: indole + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase]


name: Allergen dependent IgE bound FCERI aggregation (Mus musculus)


name: SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate (Xenopus tropicalis)


name: (S)-2-hydroxypropyl-coenzyme M + NAD(+) <=> 2-oxopropyl-coenzyme M + H(+) + NADH


name: Activation of GIRK/Kir3 Channels (Bos taurus)


name: Expression of HSP90B1 (Xenopus tropicalis)


name: H(+) + 2 H2O + monacolin L carboxylate + oxidized [NADPH--hemoprotein reductase] => dihydromonacolin L carboxylate + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+)


name: H2O + monoglucosyl-enterobactin <=> [N-(2,3-dihydroxybenzoyl)-L-seryl]2-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine + H(+)


name: GGT dimers hydrolyse APAP-SG (Rattus norvegicus)


name: 1-O-alkyl-sn-glycero-3-phosphate + an acyl-CoA = 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + CoA


name: eNOS translocation from Golgi to Caveolae (Drosophila melanogaster)


name: NCOA1 recruits EP300 to TGFA promoter (Mus musculus)


name: 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+) => 1-hexanoyl-sn-glycero-3-phosphocholine + H2O


name: diphosphate + sophoraflavanone B => (2S)-naringenin + dimethylallyl diphosphate


name: H(+) + H2O + isoguanine = NH4(+) + xanthine


name: H2O + N-hexadecanoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: oxaloacetate(in) + sulfate(out) => oxaloacetate(out) + sulfate(in)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine <=> 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA


name: Exocytosis of azurophil granule lumen proteins (Mus musculus)


name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity


name: THEM86B hydrolyses PMCHO, PMETAM (Rattus norvegicus)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Bos taurus)


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Sus scrofa)


name: 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O = 14,15-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Drosophila melanogaster)


name: VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Drosophila melanogaster)


name: 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O <=> (9Z,12Z)-octadecadienoate + a 1-acyl-sn-glycero-3-phosphocholine + H(+)


name: PIAS1,2-1 SUMOylates XRCC4 with SUMO1 (Gallus gallus)


name: 4-carboxy-2-thioxobutanoyl-CoA => 5-hydroxythiophene-2-carbonyl-CoA + H2O


name: S-adenosyl-L-methionine + syringetin <=> 3,3',5'-O-trimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: (S)-versiconol + NADP(+) <=> (2S-3S)-versiconal hemiacetal + H(+) + NADPH


name: SARDH:FAD oxidatively demethylates SARC to Gly (Bos taurus)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Danio rerio)


name: Binding of APOBEC-1 to form editosome (Bos taurus)


name: ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in) => ATP(in) + H2O(in) + Zn(2+)(out)


name: 2 dopamine + O2 = 2 dopamine quinone + 2 H2O


name: 5-taurinomethyluridine(34) in tRNA + AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] => 5-taurinomethyl-2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]


name: 4-oxo-4-(pyridin-3-yl)butanal + H2O + NADP(+) <=> 4-oxo-4-(pyridin-3-yl)butanoate + 2 H(+) + NADPH


name: PIAS1 SUMOylates THRB with SUMO1. (Homo sapiens)


name: 2-oxoglutarate + L-isoleucine + O2 => 3(1)-hydroxy-L-isoleucine + CO2 + succinate


name: RAC3 binds effectors at the plasma membrane (Homo sapiens)


name: kaempferol + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + quercetin


name: (3R)-3-hydroxy-10'-apo-beta-carotenal + O2 = (3R)-hydroxy-beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: (23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA + NADP(+) => (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA + H(+) + NADPH


name: HIF-alpha translocates from cytosol to nucleus (Bos taurus)


name: Casein kinase II phosphorylates PTEN (Sus scrofa)


name: FDPS dimer transfers IPPP to DMAPP (Rattus norvegicus)


name: AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide => H2O + NADH


name: 3,4-dihydroxyphenylethyleneglycol + NAD(+) <=> 3,4-dihydroxymandelaldehyde + H(+) + NADH


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Mus musculus)


name: ADP-alpha-D-ribose 1''-phosphate + H(+) => ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O


name: CO2 + methanol + pyropheophorbide a => H(+) + H2O + pheophorbide a


name: 6 H(+) + 2 hydrogen sulfide + 2 sulfite => 4 H2O + O2 + 4 sulfur


name: Association of procollagen type XV (Rattus norvegicus)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3) => beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: Activation of MASPs (Xenopus tropicalis)


name: ADP + H(+) + phosphate + taurolithocholate 3-sulfate(out) => ATP + H2O + taurolithocholate 3-sulfate(in)


name: FAD + H(+) + H2O + squalene => FADH2 + hydroxysqualene


name: H(+)(in) + L-glutamine(out) + Na(+)(out) => H(+)(out) + L-glutamine(in) + Na(+)(in)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 6 isopentenyl diphosphate => 6 diphosphate + tetra-trans,hexa-cis-undecaprenyl diphosphate


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Danio rerio)


name: Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)


name: 17alpha-estradiol 3-O-(beta-D-glucuronate) + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucosiduronate + H(+) + UDP


name: TRAPPC complexes exchange GTP for GDP on RAB1 (Caenorhabditis elegans)


name: Oxytocin receptor bind oxytocin (Sus scrofa)


name: 2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity


name: FAD + 2 H(+) + H2O + N-(2-methylpropyl)hydroxylamine => 2-methylpropan-1-amine + FADH2 + O2


name: Recruitment of XPA and release of CAK  (Sus scrofa)


name: MAOB inhibitors bind MAOB:FAD (Rattus norvegicus)


name: Formation of a heteromeric BMP receptor complex (Rattus norvegicus)


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Mus musculus)


name: CYP79F1 trihomomethionine monooxygenase activity


name: 2-all-trans-octaprenylphenol + H(+) + NADPH + O2 = 3-(all-trans-octaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: ATP Hydrolysis By Myosin (Canis familiaris)


name: Activated FGFR4 binds SHC1 (Mus musculus)


name: (S)-corytuberine + S-adenosyl-L-methionine => magnoflorine + S-adenosyl-L-homocysteine


name: p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Gallus gallus)


name: NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Bos taurus)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Drosophila melanogaster)


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Canis familiaris)


name: (3R)-hydroxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA + NADP(+) => (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + H(+) + NADPH


name: hexadecanoyl-CoA + tetradecan-1-ol <=> CoA + tetradecanyl hexadecanoate


name: succinyl-CoA + glycine => delta-aminolevulinate + CoA SH + CO2 (Gallus gallus)


name: a neolactoside IV(3)-beta-GlcNAc-nLc4Cer + UDP-alpha-D-galactose <=> beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer + H(+) + UDP


name: D-galactose + NADP(+) <=> D-galactono-1,5-lactone + H(+) + NADPH


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Sus scrofa)


name: hexanal + NADP(+) = (E)-hex-2-enal + H(+) + NADPH


name: ALOXE3 isomerises 12R-HpETE to HXA3 (Mus musculus)


name: Interleukin-16 is secreted (Mus musculus)


name: Release of Cytochrome c from mitochondria (Canis familiaris)


name: IL22 binds IL22RA1:JAK1 receptor complex (Xenopus tropicalis)


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-mannosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-alpha-D-mannosaminouronate


name: 2xTRAP hydrolyzes FMN to RIB (Plasmodium falciparum)


name: AcK-NFE2L2-dependent P6GD gene expression (Homo sapiens)


name: Activation of Rho by LARG and PDZ-RhoGEF (Gallus gallus)


name: asnovolin H => (3R)-[(10S)-11-epoxyfarnesyl]-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate + H(+)


name: beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP => beta-D-gentiobiosyl crocetin + UDP-alpha-D-glucose


name: GGPS1 hexamer transfers IPPP to DMAPP (Mus musculus)


name: CRHR2-2 binds CRH,UCN,UCN2,UCN3 (Rattus norvegicus)


name: dodecanedioyl-CoA + O2 = (2E)-dodecenedioyl-CoA + H2O2


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Bos taurus)


name: Phosphorylation of CARMA1 by PKC-theta (Bos taurus)


name: Phosphorylation of c-Abl and Arg by ATM (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphate + a 1-acyl-sn-glycero-3-phosphocholine <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphate


name: O2 + proatranorin II + reduced [NADPH--hemoprotein reductase] <=> H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin III


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol => a 1-acyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol


name: CYP7A1 7-hydroxylates CHOL (Xenopus tropicalis)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone <=> 2alpha,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: chloride(out) + 2 hydrogencarbonate(in) => chloride(in) + 2 hydrogencarbonate(out)


name: GALK1 phosphorylates Gal to Gal1P (Danio rerio)


name: glutathione + prostaglandin J2 = prostaglandin J2-S-(S)-glutathione


name: Histone H2A is dubiquitinated by the PR-DUB complex (Drosophila melanogaster)


name: H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate <=> CO2 + N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Homo sapiens)


name: Association of beta-catenin with the destruction complex (Caenorhabditis elegans)


name: asperlicin E + H2O + NAD(+) => asperlicin C + H(+) + NADH + O2


name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Bos taurus)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Saccharomyces cerevisiae)


name: (9Z)-octadecenoate + 1-hexadecanoylglycerone 3-phosphate => 1-(9Z)-octadecenoylglycerone 3-phosphate + hexadecanoate


name: (+)-cis-trans-nepetalactol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 7-deoxyloganetate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: SUMOylation of PIAS4 with SUMO1 (Gallus gallus)


name: 2,3',4,6-tetrahydroxybenzophenone + 3 CO2 + 4 CoA => 3-hydroxybenzoyl-CoA + 2 H(+) + 3 malonyl-CoA


name: DAXX binds Ub-MDM2 and USP7 (Bos taurus)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 reduced [electron-transfer flavoprotein] => H(+) + L-prolyl-[peptidyl-carrier protein] + 2 oxidized [electron-transfer flavoprotein]


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Plasmodium falciparum)


name: DVL1 is ubiquitinated by HECW1 (Drosophila melanogaster)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Rattus norvegicus)


name: Active IRS recruits PI3K to the plasma membrane and activates it (Homo sapiens)


name: p-S225-SPHK1 localizes to cytosol (Sus scrofa)


name: MECP2 mutants P302R,K304E,K305R,R306C,(R306H) do not bind NCoR/SMRT complex (Homo sapiens)


name: 3-maleylpyruvate + H(+) => 2,5-dihydroxybenzoate + O2


name: FAAH hydrolyses AEA to AA and ETA (Mus musculus)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate


name: (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + H2O = (-)-geosmin


name: Exocytosis of tertiary granule membrane proteins (Schizosaccharomyces pombe)


name: (E)-sinapate + ATP + CoA = (E)-sinapoyl-CoA + AMP + diphosphate


name: SRD5A3 reduces pPNOL to DCHOL (Drosophila melanogaster)


name: (9Z)-octadecenoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H(+) => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Saccharomyces cerevisiae)


name: 4-aminobenzoate + 2 H(+) + NADH + O2 = 4-aminophenol + CO2 + H2O + NAD(+)


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Plasmodium falciparum)


name: all-trans-hexaprenyl diphosphate + H2O <=> colleterpenol + diphosphate


name: Defective AVP mutants do not bind AVPR2 (Homo sapiens)


name: 4-aminobutanoate + L-arginine <=> 4-guanidinobutanoate + L-ornithine


name: a 1-acylglycerol + H2O = a fatty acid + glycerol + H(+)


name: (2R)-3-sulfopropanediol + H2O + 2 NAD(+) => (2R)-3-sulfolactate + 3 H(+) + 2 NADH


name: Connexin oligomerization in endoplasmic reticulum membrane (Sus scrofa)


name: L-threonine + uridine-5'-aldehyde <=> (5'S,6'S)-C-glycyluridine + acetaldehyde


name: a (3R)-3-[(carboxymethyl)amino]fatty acid + H(+) + holo-[ACP] => a (2E)-enoyl-[ACP] + glycine + H2O


name: BTLA interacts with HVEM (Canis familiaris)


name: ent-kaur-16-ene + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] = ent-kaur-16-en-19-oate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: PGM2:Mg2+ isomerises R1P to R5P (Danio rerio)


name: (R)-3-hydroxybutanoate(in) + 2 Na(+)(in) => (R)-3-hydroxybutanoate(out) + 2 Na(+)(out)


name: 20-hydroxyecdysone 22-phosphate + H2O => 20-hydroxyecdysone + phosphate


name: GGPS1 hexamer transfers IPPP to DMAPP (Homo sapiens)


name: OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA (Rattus norvegicus)


name: Recruitment of HDAC1 by p130 (RBL2) (Bos taurus)


name: 2-oxoglutarate + gibberellin A15 + O2 = CO2 + gibberellin A24 + H2O + succinate


name: cyclohexa-1,5-diene-1-carbonyl-CoA + H2O <=> 6-hydroxycyclohex-1-ene-1-carbonyl-CoA


name: C-terminal Hh fragments are bound by lectins (Gallus gallus)


name: docosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-docosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2 H2O + NADP(+) + stigmasterol => H(+) + NADPH + O2 + sitosterol


name: CO2 + 3 H2O + pentadecanal => H(+) + 2 H2O2 + hexadecanoate


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Xenopus tropicalis)


name: a beta-D-galactoside + acetyl-CoA => a 6-acetyl-beta-D-galactoside + CoA


name: 4-methylphenol + H2O + 4 oxidized [azurin] => 4-hydroxybenzaldehyde + 4 H(+) + 4 reduced [azurin]


name: IDS hydrolyses Heparan sulfate chain(5) (Mus musculus)


name: ent-cassa-12,15-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-11beta-hydroxycassa-12,15-diene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ERBB4 ubiquitination by WWP1/ITCH (Rattus norvegicus)


name: L-alanine(in) + L-serine(out) => L-alanine(out) + L-serine(in)


name: 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol + H(+) + UDP => (E)-sinapyl alcohol + UDP-alpha-D-glucose


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine <=> 4-O-([2-N-acetyl-alpha-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Bos taurus)


name: (6S)-5,6,7,8-tetrahydropteroate + NAD(+) <=> 7,8-dihydropteroate + H(+) + NADH


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Canis familiaris)


name: goralatide + H2O <=> L-lysyl-L-proline + N-acetyl-L-seryl-L-aspartate


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O => [DsrC protein]-S-sulfo-L-cysteine/L-cysteine + 3 AH2 + H(+)


name: Inactivation of APC/C via CDC20 sequestration (Canis familiaris)


name: glycocholate(out) + n H(+)(out) => glycocholate(in) + n H(+)(in)


name: chanoclavine-I + NAD(+) = chanoclavine-I aldehyde + H(+) + NADH


name: (R)-mandelonitrile + UDP-alpha-D-glucose => (R)-prunasin + H(+) + UDP


name: (9Z,12Z)-octadecadienoyl-CoA + 2 H(+) + 2 NADPH => (9Z,12Z)-octadecadien-1-ol + CoA + 2 NADP(+)


name: H2O + L-alanyl-L-glutamine => L-alanine + L-glutamine


name: Dab2 is recruited to the junctional plaques (Sus scrofa)


name: (2R,3S,4S)-3,4-leucopelargonidin + NADP(+) <=> (2R,3R)-dihydrokaempferol + H(+) + NADPH


name: gadusol + H(+) + S-adenosyl-L-homocysteine => demethylgadusol + S-adenosyl-L-methionine


name: type 2 fibroblast growth factor receptor binding


name: KLF5 gene expression is enhanced by CEBPA (Homo sapiens)


name: Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer (Homo sapiens)


name: ATP + holo-[peptidyl-carrier protein] + L-arginine <=> AMP + diphosphate + L-arginyl-[peptidyl-carrier protein]


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Homo sapiens)


name: D-arabino-hex-3-ulose 6-phosphate => D-ribulose 5-phosphate + formaldehyde


name: RAC3 translocates to the endoplasmic reticulum membrane (Caenorhabditis elegans)


name: NQO2:FAD dimer reduces quinones to hydroquinones (Mus musculus)


name: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Danio rerio)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) (Rattus norvegicus)


name: METAP1/2 demethylates GNAT1 (Xenopus tropicalis)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+) => 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH


name: guanosine 3'-diphosphate 5'-triphosphate + H2O = guanosine 3',5'-bis(diphosphate) + H(+) + phosphate


name: Interaction of particulate antigens with dendritic cell receptors (Gallus gallus)


name: H2O + L-alanyl-L-glutamate <=> L-alanine + L-glutamate


name: CoA + H(+) + N-tetracosanoylsphinganine => sphinganine + tetracosanoyl-CoA


name: 9-cis-retinol + NAD(+) => 9-cis-retinal + H(+) + NADH


name: Necl-1:Necl-2 trans heterodimer interaction (Bos taurus)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => (9Z)-octadecenoate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Caenorhabditis elegans)


name: a 2,3-diacyl-sn-glycerol + H2O = a 3-acyl-sn-glycerol + a fatty acid + H(+)


name: 2 glyphosate + O2 = 2 aminomethylphosphonate + 2 glyoxylate + 2 H(+)


name: pro-SFTPB translocates from ER membrane to multivesicle body (Sus scrofa)


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Danio rerio)


name: N,N',N''-triacetylchitotriose + O2 => H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone


name: L-leucine(in) + L-phenylalanine(out) => L-leucine(out) + L-phenylalanine(in)


name: a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)


name: Exocytosis of platelet dense granule content (Canis familiaris)


name: JMJD6 demethylates Me2R3-histone H3 (Caenorhabditis elegans)


name: a 3-demethylubiquinol + S-adenosyl-L-methionine <=> a ubiquinol + H(+) + S-adenosyl-L-homocysteine


name: XDH oxidizes hypoxanthine to form xanthine (Homo sapiens)


name: ATP + guanidinoacetate <=> ADP + H(+) + phosphoguanidinoacetate


name: Mitochondrial recruitment of Drp1 (Bos taurus)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Bos taurus)


name: IL12B translocates from the cytosol to the extracellular region (Canis familiaris)


name: (R)-carnitine + propanoyl-CoA => CoA + O-propanoyl-(R)-carnitine


name: a ganglioside GA1 + UDP-N-acetyl-alpha-D-glucosamine = a ganglioside beta-DGlcNAc-(1->6)-GA1 + H(+) + UDP


name: KCNIP3 binds NPAS4 gene promoter (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => H(+) + hexadecanoate + hexadecanoyl-sn-glycero-3-phosphocholine


name: H2O + substance P <=> L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-7)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Rattus norvegicus)


name: nitrate(out) + nitrite(in) => nitrate(in) + nitrite(out)


name: (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate


name: eicosan-1-ol + hexadecanoyl-CoA = CoA + eicosanyl hexadecanoate


name: acetone + H(+) + NADH => NAD(+) + propan-2-ol


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Saccharomyces cerevisiae)


name: PP2A dephosphorylates RAF1 (Caenorhabditis elegans)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Danio rerio)


name: P2Y2 receptor binds ATP and UTP (Mus musculus)


name: a (Z)-alkenyl glucosinolate + H2O => a (Z)-N-(sulfonatooxy)alkenimidothioate + D-glucose + H(+)


name: cholesterol + H(+) + NADPH + O2 => 7-dehydrocholesterol + 2 H2O + NADP(+)


name: beta-D-apiofuranosyl-(1->6)-D-glucopyranose + dalpatein + H(+) => dalpatein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O


name: HPN heterodimer cleaves pro-HGF to form HGF dimer (Rattus norvegicus)


name: sphinganine + UDP-alpha-D-galactose <=> beta-D-galactosyl-(1<->1')-sphinganine + H(+) + UDP


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Mus musculus)


name: sphinganine + tetradecanoyl-CoA => CoA + H(+) + N-(tetradecanoyl)-sphinganine


name: SEC4C,D bind GOSR2 and STX5 (Caenorhabditis elegans)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Danio rerio)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoate + H2O = (10S)-hydroxy-(6Z,12Z,15Z)-octadecatrienoate


name: Maresins translocate from cytosol to extracellular region (Homo sapiens)


name: Activated FGFR2 binds FRS2 (Gallus gallus)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Bos taurus)


name: DNA endonuclease activity, producing 3'-phosphomonoesters


name: "Endodeoxyribonucleases producing other than 5'-phosphomonoesters"


name: GSK3B phosphorylates RUNX2 (Homo sapiens)


name: ATP + CoA + dodecanoate = AMP + diphosphate + dodecanoyl-CoA


name: SGT1 binds HSP90 (Schizosaccharomyces pombe)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + sphing-4-enine => 2 Fe(III)-[cytochrome b5] + 2 H2O + sphinga-4E,14Z-dienine


name: WLS dissociates from retromer (Bos taurus)


name: FDPS dimer transfers IPPP to DMAPP (Saccharomyces cerevisiae)


name: glycine + octadecanoyl-CoA => CoA + H(+) + N-octadecanoylglycine


name: H2O + N-acetylcadaverine => acetate + cadaverine


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Canis familiaris)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Dictyostelium discoideum)


name: Granzyme-B activates BID by cleavage (Gallus gallus)


name: E2F1 binds the CDT1 gene promoter (Homo sapiens)


name: malvidin 3-O-beta-D-glucoside + UDP => malvidin + UDP-alpha-D-glucose


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Gallus gallus)


name: 4,5,8-trihydroxycasbene + 2 NAD(+) <=> 2 H(+) + jolkinol C + 2 NADH


name: RAB1:GTP recruits GBF1 to the ERGIC (Schizosaccharomyces pombe)


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate => 1D-myo-inositol hexakisphosphate + H2O


name: 2 fonsecin B + H(+) + NADPH + O2 => aurasperone B + 2 H2O + NADP(+)


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Rattus norvegicus)


name: mating-type factor pheromone receptor activity


name: (+)-premalbrancheamide + chloride + FAD + 2 H(+) <=> (+)-malbrancheamide B + FADH2


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Bos taurus)


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Homo sapiens)


name: DAG kinase produces phosphatidic acid from DAG (Xenopus tropicalis)


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Schizosaccharomyces pombe)


name: a long-chain primary fatty alcohol + H2O + 2 NAD(+) <=> a long-chain fatty acid + 3 H(+) + 2 NADH


name: (2S,3S)-3-methylphenylalanine + 2-oxoglutarate => (3S)-2-oxo-3-phenylbutanoate + L-glutamate


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Bos taurus)


name: NFE2 binds the beta globin locus control region (Sus scrofa)


name: PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Bos taurus)


name: S-adenosyl-L-methionine + uridine(2843) in 25S rRNA <=> H(+) + N(3)-methyluridine(2843) in 25S rRNA + S-adenosyl-L-homocysteine


name: PC is hydrolyzed to 2-acyl LPC by PLA2G4C (Schizosaccharomyces pombe)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Danio rerio)


name: ALAD condenses 2 dALAs to form PBG (Dictyostelium discoideum)


name: N-terminal L-cysteinyl-[protein] + O2 = H(+) + N-terminal S-hydroxy-S-oxy-L-cysteinyl-[protein]


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Homo sapiens)


name: ABHD6,12 hydrolyse 3AG (Drosophila melanogaster)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Xenopus tropicalis)


name: CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + succinate => 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + O2


name: SFTPD gene produces SFTPD protein (Homo sapiens)


name: AKR1C1 hydrogenates PREDN,PREDL (Mus musculus)


name: a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] => 7-oxoheptanoyl-[ACP] + a fatty aldehyde + H(+) + 2 H2O + oxidized [flavodoxin]


name: guanosine(2922) in 27S pre-rRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(2922) in 27S pre-rRNA + H(+) + S-adenosyl-L-homocysteine


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(in) + ATP + H2O <=> (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(out) + ADP + H(+) + phosphate


name: (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) (Rattus norvegicus)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+) => (Z)-glucotropeolin + H2O


name: CSKMT methylates Citrate Synthase (Danio rerio)


name: a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O


name: 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: a 2'-deoxyribonucleoside 5'-diphosphate + H2O => a 2'-deoxyribonucleoside 5'-phosphate + H(+) + phosphate


name: Release of the SLBP independent Histone mRNA from the NPC (Schizosaccharomyces pombe)


name: adenine(in) + H(+)(in) = adenine(out) + H(+)(out)


name: MFAP2, MFAP5 bind microfibrils (Homo sapiens)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Rattus norvegicus)


name: ent-kaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] => ent-7alpha-hydroxykaur-16-en-19-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cis-cis-nepetalactone + H(+) + NADH => cis-cis-nepetalactol + NAD(+)


name: an N-(fatty acyl)-L-isoleucine + H2O <=> a fatty acid + L-isoleucine


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Drosophila melanogaster)


name: PLC-gamma 1 binds to p-EGFRvIII mutant (Homo sapiens)


name: CBY1 binds beta-catenin (Rattus norvegicus)


name: CLN3 transports GalCer to plasma membrane (Saccharomyces cerevisiae)


name: 5 CO2 + 5 CoA + H2O + naphthalene-1,3,6,8-tetrol => 5 H(+) + 5 malonyl-CoA


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Mus musculus)


name: L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-homocysteine


name: PTK6 phosphorylates KHDRBS3 (Mus musculus)


name: GBA2 hydrolyzes GlcCer (plasma membrane) (Sus scrofa)


name: ECE1 cleaves EDN1(53-90) (Rattus norvegicus)


name: MITF-M dimer and TFAP2A bind the IRF4 gene (Homo sapiens)


name: (S)-malyl N-acetyl-alpha-D-glucosaminide + H2O = (S)-malyl alpha-D-glucosaminide + acetate


name: TNFRSF6B binds TNFSF6,14,15 (Homo sapiens)


name: NaS1 co-transports sulphate and a sodium ion (Homo sapiens)


name: CMKLR1 binds Resolvin E1 (Gallus gallus)


name: Phosphorylation of H2AX at S139 by ATM at the site of DSB (Gallus gallus)


name: acetyl-coenzyme A:acetyl alcohol acetyltransferase activity


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphate = a 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Mus musculus)


name: 4-hydroxy-2-oxobutanal + L-lysyl-[protein] + phosphate => H2O + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein]


name: (2E)-tetracosenoyl-CoA + H(+) + NADH = NAD(+) + tetracosanoyl-CoA


name: HSD17B11 dehydrogenates EST17b to E1 (Canis familiaris)


name: (R)-4'-phospho-S-sulfopantetheine + H2O => (R)-S-sulfopantetheine + phosphate


name: NT5C2 tetramer dephosphorylates RBV-MP (Caenorhabditis elegans)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  (Xenopus tropicalis)


name: 3-oxohexanoyl-[ACP] + CO2 + CoA => butanoyl-CoA + H(+) + malonyl-[ACP]


name: 2-methylpropan-1-amine + FMNH2 + O2 = FMN + 2 H(+) + H2O + N-(2-methylpropyl)hydroxylamine


name: a (2R)-2-hydroxycarboxylate + NAD(+) <=> a 2-oxocarboxylate + H(+) + NADH


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Dictyostelium discoideum)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Xenopus tropicalis)


name: Recruitment of POLB to the AP site (Dictyostelium discoideum)


name: histone H3K27 monomethyltransferase activity


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Rattus norvegicus)


name: benzoyl-CoA + H(+) + NADPH + O2 = 3-hydroxybenzoyl-CoA + H2O + NADP(+)


name: 3'-phosphoadenylyl sulfate + an alcohol => adenosine 3',5'-bisphosphate + an alkyl sulfate + H(+)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Canis familiaris)


name: L-arginocholate + taurine => L-arginine + taurocholate


name: decanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-decenoyl-CoA + reduced [electron-transfer flavoprotein]


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Rattus norvegicus)


name: PP2A-PP2R5C dephosphorylates MDM2 (Xenopus tropicalis)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Drosophila melanogaster)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Dictyostelium discoideum)


name: NDUF subunits bind to form the FP subcomplex (Rattus norvegicus)


name: an acyl-CoA + zymosterol = CoA + zymosterol ester


name: NEIL1 cleaves DHU from damaged DNA (Canis familiaris)


name: Recruitment of Dna2 endonuclease (Sus scrofa)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Bos taurus)


name: RNF20:RNF40 monoubiquitinates Histone H2B (Bos taurus)