name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Gallus gallus)


name: (9Z)-octadecenoyl-CoA + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) <=> 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: PTPN18 binds ERBB2:EGFR heterodimers (Homo sapiens)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Homo sapiens)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)


name: a secondary alcohol + O2 => a ketone + H2O2


name: RNF181 binds BCL10 and Ubiquitin:E2 (Mus musculus)


name: Ferriheme is transferred from Methemoglobin to Hemopexin (Xenopus tropicalis)


name: ATP + citrate + D-ornithine => AMP + diphosphate + H(+) + N(5)-[(S)-citryl]-D-ornithine


name: Phosphopantetheine conjugation of the ACP domain of FAS (Drosophila melanogaster)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Caenorhabditis elegans)


name: CoA + H(+) + N-octadecanoyl-sphinga-4E,14Z-dienine => octadecanoyl-CoA + sphinga-4E,14Z-dienine


name: O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2 <=> 18-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Gallus gallus)


name: ROBO3.1 expression is stimulated by LHX2,(LHX9) (Homo sapiens)


name: acetyl-CoA + D-alanine => (2R)-2-amino-4-oxopentanoate + CoA


name: Dephosphorylation of p107 (RBL1) by PP2A (Drosophila melanogaster)


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Homo sapiens)


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine = 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Drosophila melanogaster)


name: chenodeoxycholate + NADP(+) => 3-oxochenodeoxycholate + H(+) + NADPH


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Rattus norvegicus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Gallus gallus)


name: RHOT1 binds effectors at the mitochondrial outer membrane (Homo sapiens)


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Xenopus tropicalis)


name: ADP(out) + ATP(in) + H(+)(out) + Mg(2+)(in) = ADP(in) + ATP(out) + H(+)(in) + Mg(2+)(out)


name: (S)-malate + UDP-N-acetyl-alpha-D-glucosamine = (S)-malyl N-acetyl-alpha-D-glucosaminide + H(+) + UDP


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Canis familiaris)


name: (9Z)-octadecenoate + 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) => 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + H2O


name: MDM2 ubiquitinates JMY (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in)


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Caenorhabditis elegans)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Canis familiaris)


name: 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 4beta-methylzymosterol-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate => 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: FAS-mediated dimerization of procaspase-8 (Canis familiaris)


name: Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex (Gallus gallus)


name: (2R,3S)-2,3-dimethylmalate <=> dimethylmaleate + H2O


name: SLC36A1-mediated uptake of glycine, proline, and alanine (Dictyostelium discoideum)


name: KCNJs transport K+ from the extracellular region to cytosol (Mus musculus)


name: nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Bos taurus)


name: p-T774-PKN1 phosphorylates PPP1R14A (Mus musculus)


name: Interaction of Tie2 and Grb2 (Bos taurus)


name: an alditol + NAD(+) => an aldose + H(+) + NADH


name: I-Smad competes with Co-Smad for R-Smad1/5/8 (Drosophila melanogaster)


name: IQGAP1 binds CLIP1 and microtubules (Bos taurus)


name: p75NTR:NADE promotes caspase2/3 activation (Mus musculus)


name: Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Gallus gallus)


name: Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 (Bos taurus)


name: p-S207 KARS displaces HINT1 (Bos taurus)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA


name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Dictyostelium discoideum)


name: STAB1 (FEEL-1) binds ligands (Homo sapiens)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Canis familiaris)


name: Cleavage of uracil by UNG glycosylase (Gallus gallus)


name: 2-dehydro-D-gluconate + FADH2 => D-gluconate + FAD + H(+)


name: Frataxin binds iron (Drosophila melanogaster)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Rattus norvegicus)


name: TXNIP binds reduced thioredoxin (Mus musculus)


name: 2-oxoglutarate + L-isoleucine + O2 <=> 3(1)-hydroxy-L-isoleucine + CO2 + succinate


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  upon TLR7/8 or 9 activation (Xenopus tropicalis)


name: 2 ATP + L-alanine + L-tryptophan => 2 ADP + cyclo(L-tryptophyl-L-alanyl) + 2 H(+) + 2 phosphate


name: (4R)-hydroxyeicosasphinganine + a fatty acyl-CoA = CoA + H(+) + N-acyl-4-hydroxyeicosasphinganine


name: citrate(in) + H(+)(in) => citrate(out) + H(+)(out)


name: RB1 translocates to the nucleus (Sus scrofa)


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Homo sapiens)


name: Slo3 Potassium Transport (Caenorhabditis elegans)


name: H2O + octadecanamide = NH4(+) + octadecanoate


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Danio rerio)


name: 2-deoxy-D-ribose + ATP = 2-deoxy-D-ribose 5-phosphate + ADP + H(+)


name: H2O + O2 + tyramine <=> (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NAD(+) + resolvin D2 = 7-oxoresolvin D2 + H(+) + NADH


name: Growth hormone receptor dimerizes (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone <=> 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: oxalate + succinyl-CoA <=> oxalyl-CoA + succinate


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Mus musculus)


name: MANBA hydrolyses GlcNAc:Man (Dictyostelium discoideum)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Gallus gallus)


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Homo sapiens)


name: ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Bos taurus)


name: BTK in active Gq-BTK complex is activated (Bos taurus)


name: beta-alanyl-5'-AMP + holo-[peptidyl-carrier protein] = AMP + beta-alanyl-[peptidyl-carrier protein] + H(+)


name: a 5'-end ribonucleotide-RNA + a ribonucleoside 5'-triphosphate + ATP + H2O <=> a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + AMP + 2 diphosphate + H(+)


name: Caspase-mediated cleavage of Desmoglein 1 (Homo sapiens)


name: dopamine(out) + 2 H(+)(in) => dopamine(in) + 2 H(+)(out)


name: 1-hexadecanoylglycerone 3-phosphate + octadecan-1-ol = 1-O-octadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: Activated PTK6 binds CDKN1B (Danio rerio)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Sus scrofa)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Bos taurus)


name: NAD(+) + sn-glycerol 3-phosphate => dihydroxyacetone phosphate + H(+) + NADH


name: Autocatalytic activation of MMP1 (Canis familiaris)


name: Activated PLC gamma dissociates from the PDGF receptor (Homo sapiens)


name: 2-hydroxyhexacosanoyl-CoA + sphinganine = CoA + H(+) + N-(2-hydroxyhexacosanoyl)-sphinganine


name: TP53 family members bind PPP1R13B or TP53BP2 (Danio rerio)


name: L-ascorbate 6-phosphate lactonase activity


name: H2O + L-ascorbate 6-phosphate = 3-dehydro-L-gulonate 6-phosphate


name: [deoxyhypusine synthase]-L-lysine + dehydrospermidine <=> [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine


name: AKR1B1 reduces Glc to D-sorbitol (Saccharomyces cerevisiae)


name: CO + CoA + methyl-Co(III)-[corrinoid Fe-S protein] => acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+)


name: Collagen type III degradation by MMP15 (Sus scrofa)


name: arginine + glycine => ornithine + guanidoacetate (Xenopus tropicalis)


name: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil


name: Recruitment of HDAC1 by p130 (RBL2) (Sus scrofa)


name: NOTCH1 stimulates HES1 transcription (Homo sapiens)


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: dodecanoyl-CoA + hexadecan-1-ol => CoA + hexadecanyl dodecanoate


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Bos taurus)


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)


name: 3-hydroxy-2-methylpyridine-5-carboxylate + NADH + O2 => 2-(acetamidomethylene)succinate + NAD(+)


name: SUMOylation of NOP58 with SUMO1 (Sus scrofa)


name: Addition of nucleotides 5 through 9 on the growing HIV-1 transcript (Homo sapiens)


name: L-phenylalanine(out) + L-serine(in) <=> L-phenylalanine(in) + L-serine(out)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Dictyostelium discoideum)


name: CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Mus musculus)


name: YAP1 binds ZO-2 (TJP2) (Xenopus tropicalis)


name: 4-hydroxy-L-proline(in) + Na(+)(in) <=> 4-hydroxy-L-proline(out) + Na(+)(out)


name: CO2 + H(+) + succinate + validoxylamine B => 2-oxoglutarate + O2 + validoxylamine A


name: UBQLNs bind UIM-containing adaptor proteins (Dictyostelium discoideum)


name: H(+) + heptan-2-one + NADH + NH4(+) => (2R)-heptan-2-amine + H2O + NAD(+)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Bos taurus)


name: adenosine(58) in tRNA + CO2 + formaldehyde + succinate => 2-oxoglutarate + N(1)-methyladenosine(58) in tRNA + O2


name: (R)-malate + NAD(+) = CO2 + NADH + pyruvate


name: H(+) + NADP(+) + 2 reduced [2Fe-2S]-[protein] => NADPH + 2 oxidized [2Fe-2S]-[protein]


name: 2 acetyl-CoA + 3 H(+) + 6 malonyl-CoA + 2 S-adenosyl-L-methionine => 4-O-demethylbarbatate + 6 CO2 + 8 CoA + H2O + 2 S-adenosyl-L-homocysteine


name: H(+) + L-xylono-1,4-lactone + NADPH => L-xylose + NADP(+)


name: Transport of MHC II:Ii complex along Golgi to TGN (Sus scrofa)


name: Association of beta-catenin with the destruction complex (Homo sapiens)


name: atRAL is reduced to atROL (Caenorhabditis elegans)


name: ethanolamine + phosphate => H2O + phosphoethanolamine


name: ATP + H2O + taurochenodeoxycholate(in) => ADP + H(+) + phosphate + taurochenodeoxycholate(out)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Caenorhabditis elegans)


name: (2E,6E,10E)-geranylgeraniol + UTP = (2E,6E,10E)-geranylgeranyl phosphate + H(+) + UDP


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Rattus norvegicus)


name: 2-hydroxyoctadecanoyl-CoA + sphinganine <=> CoA + H(+) + N-(2-hydroxyoctadecanoyl)-sphinganine


name: Binding of RRN3 to RNA Polymerase I (Canis familiaris)


name: BPHL hydrolyses VACV to ACV (Mus musculus)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Canis familiaris)


name: ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans (Homo sapiens)


name: COPI vesicle uncoating at the ER (Canis familiaris)


name: 6-phospho-D-gluconate + NAD(+) => 6-phospho-2-dehydro-D-gluconate + H(+) + NADH


name: (+)-minovincinine + acetyl-CoA <=> (+)-echitovenine + CoA


name: NOX2 generates superoxide from oxygen (Rattus norvegicus)


name: glutathione + prostaglandin J2 => prostaglandin J2-S-(S)-glutathione


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Sus scrofa)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Mus musculus)


name: 2 a 1-acyl-sn-glycerol => a 1,2-diacyl-sn-glycerol + glycerol


name: FAD + H(+) + pentadecanoyl-CoA <=> (2E)-pentadecenoyl-CoA + FADH2


name: an alpha-(gamma-L-glutamyl)-L-amino acid = 5-oxo-L-proline + an L-alpha-amino acid


name: Neuropeptide S receptor binds neuropeptide S (Bos taurus)


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Bos taurus)


name: ATP + D-arabinose = ADP + D-arabinose 5-phosphate + H(+)


name: H(+) + N,N',N''-triacetylchitotrionate => H2O + N,N',N''-triacetylchitotriono-1,5-lactone


name: ELANE, CTSG or PRTN3 binds bacteria (Homo sapiens)


name: all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: 3-oxo-(10Z,13Z,16Z)-docosatrienoyl-CoA + CO2 + CoA => (8Z,11Z,14Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Gallus gallus)


name: GLUT1 tetramer binds 4xATP (Mus musculus)


name: alpha-nootkatol + O2 + reduced [NADPH--hemoprotein reductase] <=> (+)-nootkatone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Syk activation leads to SLP-76 activation (Mus musculus)


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Mus musculus)


name: H2O + prostaglandin F2alpha-CoA => CoA + H(+) + prostaglandin F2alpha


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Bos taurus)


name: Cation influx mediated by TRPC3/6/7 (Gallus gallus)


name: ATP + H2O + L-alanyl-L-histidine(out) = ADP + H(+) + L-alanyl-L-histidine(in) + phosphate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine => H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine


name: FECH binds Fe2+ to PRIN9 to form heme (Sus scrofa)


name: D-sorbitol 6-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH


name: Cargo Recognition And Sorting (Mus musculus)


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Rattus norvegicus)


name: 3 ATP = 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 diphosphate


name: ADRA2A,B,C bind ADR,NAd (Caenorhabditis elegans)


name: 2 Fe(III)-[leghemoglobin] + NADPH = 2 Fe(II)-[leghemoglobin] + H(+) + NADP(+)


name: DAG stimulates protein kinase C-delta (Gallus gallus)


name: (R)-beta-alanopine + H2O + NAD(+) <=> beta-alanine + H(+) + NADH + pyruvate


name: CYP3A4 oxidizes PREDN,PREDL (Gallus gallus)


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Plasmodium falciparum)


name: Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Sus scrofa)


name: D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate = diphosphate + lydicene


name: CEBPB homodimerization (Rattus norvegicus)


name: glycyl-L-aspartate(in) + 2 H(+)(in) => glycyl-L-aspartate(out) + 2 H(+)(out)


name: 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: BCDX2 complex stabilizes RAD51 filament (Sus scrofa)


name: a menaquinol + 2 nitric oxide = a menaquinone + H2O + nitrous oxide


name: SALMs 1-3 bind to PSD-95 family members (Homo sapiens)


name: 2-hydroxyheptadecanoyl-CoA + CO2 + succinate => 2-oxoglutarate + heptadecanoyl-CoA + O2


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Bos taurus)


name: Cross-linking of FCGRIIA with IgG-coated Ag (Rattus norvegicus)


name: ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA (Sus scrofa)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Sus scrofa)


name: CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Bos taurus)


name: a ganglioside GA2 (d18:1(4E)) + H(+) + UDP => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Mus musculus)


name: N-terminal protein N-methyltransferase activity


name: D-glucose(out) + H(+)(in) <=> D-glucose(in) + H(+)(out)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine


name: CFTR binds components of the ERAD machinery for ubiquitination and degradation (Bos taurus)


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Homo sapiens)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate = ectocarpin B + H2O


name: 2-oxoglutarate + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactose + L-glutamate


name: ALPK1:ADP-heptose binds TIFA (Sus scrofa)


name: 2-oxoglutarate + L-lysyl-[collagen] + O2 => (5R)-5-hydroxy-L-lysyl-[collagen] + CO2 + succinate


name: dihydrorhizobitoxine + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + rhizobitoxine


name: (20S)-ginsenoside Rb2 + 2 H2O = (20S)-ginsenoside C-Y + 2 D-glucose


name: Fibronectin degradation by MMP14 (Sus scrofa)


name: 1,8-cineole + diphosphate => (2E)-geranyl diphosphate + H2O


name: 7-oxocholesterol + H(+) + NADPH => 7alpha-hydroxycholesterol + NADP(+)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Sus scrofa)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Canis familiaris)


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)


name: resorcinol + S-adenosyl-L-methionine => 3-methoxyphenol + H(+) + S-adenosyl-L-homocysteine


name: dihydrophloroglucinol + NADP(+) => 1,3,5-trihydroxybenzene + NADPH


name: [5-(aminomethyl)furan-3-yl]methyl diphosphate + gamma-L-glutamyltyramine => (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 <=> 1-O-methyl-(9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: AMP + diphosphate + nonadecanoyl-CoA => ATP + CoA + nonadecanoate


name: SUMOylation of NOP58 with SUMO1 (Mus musculus)


name: CTSG cleaves CASP1(1-404) (Homo sapiens)


name: TP53 binds the NDRG1 gene promoter (Homo sapiens)


name: Phosphorylation of SRC-1 (Caenorhabditis elegans)


name: LCNs bind lipids (Drosophila melanogaster)


name: VD3 translocates from ER membrane to extracellular region (Homo sapiens)


name: carbovir + IMP => carbovir monophosphate + inosine (Gallus gallus)


name: 3-O-(beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-L-Fuc)-L-threonyl-[EGF-like domain protein] + H(+) + UDP => 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-alpha-D-galactose


name: 2 AH2 + all-trans-zeta-carotene => 15-cis-phytoene + 2 A


name: Dopachrome is transformed to DHICA by DCT (Homo sapiens)


name: A1 and A3 receptors bind adenosine (Caenorhabditis elegans)


name: 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH => L-threo-tetrahydrobiopterin + 2 NADP(+)


name: 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine <=> 8-demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Danio rerio)


name: (E)-ferulate + ATP + CoA = (E)-feruloyl-CoA + ADP + phosphate


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Schizosaccharomyces pombe)


name: GGT dimers hydrolyse GSH (Canis familiaris)


name: Formation of collagen fibrils (Drosophila melanogaster)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Drosophila melanogaster)


name: RHOB binds effectors on endosomes (Xenopus tropicalis)


name: a 1,3-diacyl-sn-glycerol + H2O = a fatty acid + a monoacylglycerol + H(+)


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Caenorhabditis elegans)


name: 3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate + H(+)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Xenopus tropicalis)


name: n H(+)(out) + spermine(in) => n H(+)(in) + spermine(out)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Dictyostelium discoideum)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Schizosaccharomyces pombe)


name: cyclic nucleotide-activated monoatomic ion channel activity


name: AKR1B15 reduces EST17b to E1 (Mus musculus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: CDP-DAG is converted to PI by CDIPT (Homo sapiens)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)


name: Receptor CCR7 binds CCL19 and 21 ligands (Danio rerio)


name: PAK binds RAC and bPIX (Rattus norvegicus)


name: NADH + 2 oxidized [2Fe-2S]-[ferredoxin] => H(+) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Activation of Calcineurin (Drosophila melanogaster)


name: (1-deoxy-D-fructos-1-yl)amine + 6-amino-2-oxohexanoate + H2O2 => H2O + N(2)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2


name: (3beta)-hydroxy-cholest-5-en-26-al + NADPH + O2 = (3beta)-hydroxy-cholest-5-en-26-oate + H2O + NADP(+)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: L-glutamine(out) + L-serine(in) + Na(+)(out) = L-glutamine(in) + L-serine(out) + Na(+)(in)


name: CCNK binds CDK12 (Dictyostelium discoideum)


name: CoA + H(+) + olivetolate => 3,5,7-trioxododecanoyl-CoA


name: ATP + UDP-N-acetyl-alpha-D-glucosamine => ADP + H(+) + UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate


name: 2-all-trans-hexaprenylphenol + CO2 => 4-hydroxy-3-all-trans-hexaprenylbenzoate + H(+)


name: H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UTP => diphosphate + UDP-N-acetyl-alpha-D-galactosamine


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Schizosaccharomyces pombe)


name: (R)-sec-butylamine + H2O + NAD(+) = butan-2-one + H(+) + NADH + NH4(+)


name: UDP-beta-L-arabinofuranose(in) + UMP(out) <=> UDP-beta-L-arabinofuranose(out) + UMP(in)


name: EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue (Mus musculus)


name: 4-hydroxy-L-threonine + ATP = 4-(phosphooxy)-L-threonine + ADP + H(+)


name: 5alpha-pregnan-20beta-ol-3-one + NAD(+) = 5alpha-pregnane-3,20-dione + H(+) + NADH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA


name: 2xENPP1 hydrolyzes FAD to FMN (Sus scrofa)


name: CYP3A4,5 oxidise AFB1 to AFXBO (Homo sapiens)


name: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Dictyostelium discoideum)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Homo sapiens)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Canis familiaris)


name: guanosine(out) + H(+)(out) => guanosine(in) + H(+)(in)


name: 8-oxo-dGTP + 2 H2O => 8-oxo-dGMP + 2 H(+) + 2 phosphate


name: glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Rattus norvegicus)


name: cholesteryl (9Z-octadecenoate) + H2O <=> (9Z)-octadecenoate + cholesterol + H(+)


name: (24S)-7alpha-dihydroxycholesterol + NAD(+) <=> (24S)-7alpha,24-dihydroxycholest-4-en-3-one + H(+) + NADH


name: ERK5 translocates to the nucleus (Mus musculus)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Canis familiaris)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Rattus norvegicus)


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Bos taurus)


name: D-ribulose 5-phosphate + L-tryptophan => (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + formaldehyde + H(+) + H2O + hydroxyacetone + phosphate


name: all-trans-zeaxanthin + O2 = (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone


name: (R)-carnitine + 4,8-dimethylnonanoyl-CoA => CoA + O-4,8-dimethylnonanoyl-(R)-carnitine


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: protein tyrosine phosphatase activity, via thiol-phosphate intermediate


name: Proglucagon translocates from the ER Lumen to secretory granules (Rattus norvegicus)


name: 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: Formation of Pol zeta complex (Gallus gallus)


name: cholesterol + 6 H(+) + 3 O2 + 6 reduced [adrenodoxin] = 4-methylpentanal + 4 H2O + 6 oxidized [adrenodoxin] + pregnenolone


name: isoorientin + S-adenosyl-L-methionine => H(+) + isoscoparin + S-adenosyl-L-homocysteine


name: TGFBR3 translocation to plasma membrane (Canis familiaris)


name: AGK:Mg2+ phosphorylates MAG, DAG (Bos taurus)


name: PTPS is phosphorylated by cGMP-dependant protein kinase II (Mus musculus)


name: 2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Homo sapiens)


name: Protein Kinase B (AKT) phosphorylates KSRP (Drosophila melanogaster)


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex  (Rattus norvegicus)


name: Activated ERBB2 binds PTK6 (BRK) (Danio rerio)


name: 3alpha-hydroxy-5alpha-pregnan-20-one + NAD(+) <=> 5alpha-pregnane-3,20-dione + H(+) + NADH


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Caenorhabditis elegans)


name: thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators (Gallus gallus)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Bos taurus)


name: Activated FGFR4 mutants phosphorylate PLCG1 (Homo sapiens)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Homo sapiens)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Plasmodium falciparum)


name: JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 (Homo sapiens)


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Rattus norvegicus)


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Dictyostelium discoideum)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Danio rerio)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Xenopus tropicalis)


name: MAOB inhibitors bind MAOB:FAD (Xenopus tropicalis)


name: PKA phosphorylates MAPKAPK5 (Bos taurus)


name: glycyl-L-glutamate(out) + 3 H(+)(out) = glycyl-L-glutamate(in) + 3 H(+)(in)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Mus musculus)


name: MAOB inhibitors bind MAOB:FAD (Canis familiaris)


name: HMG CoA => acetoacetic acid + acetyl CoA (Bos taurus)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Sus scrofa)


name: SUMOylation of NR3C1 (GR) with SUMO1 (Rattus norvegicus)


name: Activation of Potassium transport channels (Danio rerio)


name: CYP2D6 4-hydroxylates debrisoquine (Drosophila melanogaster)


name: Protein 4.1 binds CASK (Drosophila melanogaster)


name: C3PO hydrolyzes cleaved passenger strand (Schizosaccharomyces pombe)


name: 5-hydroxyuridine + ATP <=> 5-hydroxyuridine 5'-phosphate + ADP + H(+)


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Xenopus tropicalis)


name: Some HSPGs are secreted to the plasma membrane (Mus musculus)


name: 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose = 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP


name: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O <=> (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H(+)


name: IL36RN, IL1F10 bind IL1RL2 (Canis familiaris)


name: Nuclear VBC complex ubiquitinylates HIF-alpha (Mus musculus)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Rattus norvegicus)


name: [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine <=> [LarE protein]-dehydroalanine + H(+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: H(+) + O-beta-D-glucosyl-cis-zeatin + UDP => cis-zeatin + UDP-alpha-D-glucose


name: Activation of BAD by calcineurin (Canis familiaris)


name: a 1,2-diacyl-sn-glycerol + CoA => a 1-acyl-sn-glycerol + an acyl-CoA


name: Potassium voltage-gated channels close in reponse to PKA (Bos taurus)


name: beta-D-glucose 1-phosphate + glycerol => 2-O-(alpha-D-glucopyranosyl)glycerol + phosphate


name: MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Rattus norvegicus)


name: cholesterol + glycyl-L-cysteinyl-[protein] + H(+) = [protein]-C-terminal glycyl cholesterol ester + N-terminal L-cysteinyl-[protein]


name: 2-phenylacetate + CoA + H(+) => H2O + phenylacetyl-CoA


name: TRAF6 is K63 poly-ubiquitinated (Bos taurus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Gallus gallus)


name: PTPRZ dephosphorylates ligand-bound ALK dimers (Rattus norvegicus)


name: L-alanine(out) + L-aspartate(in) => L-alanine(in) + L-aspartate(out)


name: (Z)-3-ureidoacrylate + H(+) + H2O => (Z)-3-aminoacrylate + CO2 + NH4(+)


name: 3-dehydro-L-gulonate 6-phosphate => H2O + L-ascorbate 6-phosphate


name: Release of 40S and 60S subunits from the 80S ribosome  (Drosophila melanogaster)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Mus musculus)


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) <=> 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADPH


name: avenacoside A + H2O => 26-desgluco-avenacoside A + D-glucose


name: (3R)-hydroxy-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA <=> (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H2O


name: Expression of PRDM1 in primordial germ cells (Homo sapiens)


name: Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 (Homo sapiens)


name: (5,6,15R)-trihydroxy-(7E,9E,11Z,13E,17Z)-eicosapentaenoate => (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + O2


name: chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] = alpha-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: UGTs glucuronate APAP to APAP-GlcA (Bos taurus)


name: lactate transmembrane transporter activity


name: TFIIS-mediated recovery of elongation from arrest (Xenopus tropicalis)


name: HSP70 binds to HSP40:nascent protein (Bos taurus)


name: a very long-chain fatty acid(in) + ATP + H2O = a very long-chain fatty acid(out) + ADP + H(+) + phosphate


name: 2'-deoxyinosine(out) + H(+)(out) => 2'-deoxyinosine(in) + H(+)(in)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O => (6S)-5,6,7,8-tetrahydrofolate + formaldehyde


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycerol + H(+) + phosphocholine


name: Caspase 3-mediated cleavage of PKC delta (Xenopus tropicalis)


name: PGG2 is reduced to PGH2 by PTGS2 (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate <=> 1-(9Z-octadecenoyl)-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: Formation of the SET1A complex (Saccharomyces cerevisiae)


name: all-trans-heptaprenyl diphosphate + sn-glycerol 1-phosphate => 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate


name: Translocation of Vav1 to CD28 (Homo sapiens)


name: ACO2 isomerizes citrate (Dictyostelium discoideum)


name: BRAP autoubiquitinates (Rattus norvegicus)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Canis familiaris)


name: 4-methylsulfanyl-2-oxobutanoate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-methionine


name: L-cysteine(out) + Na(+)(out) => L-cysteine(in) + Na(+)(in)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: ATP + D-maltose(out) + H2O <=> ADP + D-maltose(in) + H(+) + phosphate


name: NFkB complex translocates from the cytosol to the nucleus (Rattus norvegicus)


name: NEK6/NEK7 phosphorylates NUP98 (Sus scrofa)


name: (6R)-10-formyltetrahydrofolate + GDP-alpha-D-perosamine = (6S)-5,6,7,8-tetrahydrofolate + GDP-N-formyl-alpha-D-perosamine + H(+)


name: (3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) <=> [(3R)-hydroxybutanoate](n+1) + CoA


name: beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + H(+) + UDP => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-glucosamine


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Canis familiaris)


name: (1S)-1,23,25-trihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin] => (1S)-1,25-dihydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: Receptor FFAR3 binds carboxylates (Homo sapiens)


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Drosophila melanogaster)


name: FeHM dissociates from MetHb (Rattus norvegicus)


name: ULK1 is dephosphorylated (Canis familiaris)


name: CMP-beta-3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + diphosphate => 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + CTP


name: HTRA1 hydrolyzes ACAN (Aggrecan) (Mus musculus)


name: PIAS1 SUMOylates SATB2 with SUMO3 (Homo sapiens)


name: glyoxylate + N(omega),N('omega)-dimethyl-L-arginine => 5-(3,3'-dimethylguanidino)-2-oxopentanoate + glycine


name: NPPA(124-151) binds NPR1 (Canis familiaris)


name: folate + H(+) + NADPH => 7,8-dihydrofolate + NADP(+)


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2A (GRIN2A) (Caenorhabditis elegans)


name: 2-oxoglutarate + H(+) + L-glutamine + NADH => 2 L-glutamate + NAD(+)


name: D-ribitol 5-phosphate + NADP(+) <=> D-ribulose 5-phosphate + H(+) + NADPH


name: 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-[citrate lyase ACP] <=> diphosphate + holo-[citrate lyase ACP]


name: CTLH E3 ligase ubiquitinates LDHA (Mus musculus)


name: CARM1 methylates arginine-27 of histone H3 (H3R26) (Sus scrofa)


name: Regulation of KIF20A (MKL2) by phosphorylation (Mus musculus)


name: p-ULK1 phosphorylates DENND3 (Mus musculus)


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Dictyostelium discoideum)


name: CSF3R binds CSF3 dimer (Canis familiaris)


name: POLZ elongates POLI-incorporated dNMP (Plasmodium falciparum)


name: CP110 and CEP97 dissociate from the centriole (Homo sapiens)


name: 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA => 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: H2O + N-acyl-sn-glycero-3-phosphoethanolamine <=> an N-acylethanolamine + H(+) + sn-glycerol 3-phosphate


name: Caspase-mediated cleavage of Etk (Rattus norvegicus)


name: 2-dehydro-3-deoxy-D-gluconate + ATP => 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+)


name: 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphocholine + CoA => (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Gallus gallus)


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Canis familiaris)


name: B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Sus scrofa)


name: ATM phosphorylates TP53 at S15 (Canis familiaris)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Mus musculus)


name: apo-[corrinoid adenosyltransferase] + cob(II)yrinate a,c diamide => cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase]


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] = 1,5-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Ubiquitinated RNF41 binds P-USP8 (Rattus norvegicus)


name: CHRM2,4 bind acetylcholine (Danio rerio)


name: DHF is reduced to tetrahydrofolate (THF) (Caenorhabditis elegans)


name: LAG3 (CD233) binds MHC II (Mus musculus)


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) => 5alpha-androstan-3,17-dione + H(+) + NADPH


name: PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Rattus norvegicus)


name: ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC (Homo sapiens)


name: AMP + diphosphate + H(+) + N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine => ATP + citrate + N(6)-acetyl-N(6)-hydroxy-L-lysine


name: 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 23S,25-dihydroxy-24-oxocholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: NID1 degradation by MMP19 (Homo sapiens)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Plasmodium falciparum)


name: baicalein + UDP-alpha-D-glucuronate <=> baicalin + UDP


name: (R)-lactate + H(+) + sulfate => (R)-2-O-sulfolactate + H2O


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Caenorhabditis elegans)


name: 4-aminobutanoate + L-lysine => H2O + N(2)-(4-aminobutanoyl)-L-lysine


name: Conversion of glyoxylate to oxalate (Caenorhabditis elegans)


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Caenorhabditis elegans)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Danio rerio)


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Mus musculus)


name: Unwinding of DNA for the Nascent Transcript: Second Transition (Drosophila melanogaster)


name: (3S)-3-hydroxy-D-aspartate <=> H2O + iminosuccinate


name: CA4:Zn2+ hydrates CO2 to HCO3- (Mus musculus)


name: 3,4-dihydroxyphenylacetate + O2 => 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)


name: ACSS3 ligates CoA to CH3COO- (Canis familiaris)


name: H(+) + N(4)-(beta-D-glucosyl)-L-asparaginyl-[protein] + UDP => L-asparaginyl-[protein] + UDP-alpha-D-glucose


name: Formation of cap binding complex (CBC) (Caenorhabditis elegans)


name: eNOS associates with Caveolin-1 (Bos taurus)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Sus scrofa)


name: YKI binds to HTH and TSH and activates transcription (Drosophila melanogaster)


name: Deubiquitination of RNF41 by P-USP8 (Gallus gallus)


name: Nectin 2 binds CD226 (Rattus norvegicus)


name: 5-methylsulfanyl-2,3-dioxopentyl phosphate <=> 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Schizosaccharomyces pombe)


name: a 3-oxoacyl-[ACP] + H(+) + NADH => a (3R)-hydroxyacyl-[ACP] + NAD(+)


name: HP1 alpha binds Histone H3K9(me)3 (Gallus gallus)


name: KRAB-ZFP binds retroelement DNA in chromatin (Rattus norvegicus)


name: ATAT acetylates microtubules (Xenopus tropicalis)


name: a guanosine in RNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in RNA + S-adenosyl-L-homocysteine


name: NFE2L2-dependent PRDX1 gene expression (Homo sapiens)


name: ADP + D-mannose 6-phosphate + H(+) => ATP + D-mannose


name: PI(3,5)P2 transports from the late endosome membrane to the Golgi membrane (Homo sapiens)


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Homo sapiens)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Sus scrofa)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oate = 3-oxochola-4,6-dien-24-oate + H2O


name: 5,10-methylenetetrahydromethanopterin + H(+) => 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2


name: MAPK4,6 translocate to nucleus (Schizosaccharomyces pombe)


name: Fe(III)-[cytochrome c] + H2O + nitric oxide = Fe(II)-[cytochrome c] + 2 H(+) + nitrite


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + octadecanoyl-CoA => (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: H2O + N-(4-aminobutylpyrrolinium) ion + O2 = H2O2 + N-(4-oxobutylpyrrolinium) ion + NH4(+)


name: Heterodimerization of CEACAMs (Bos taurus)


name: Phosphorylation of PLC-gamma1 (Xenopus tropicalis)


name: "Acid--ammonia (or amine) ligases (amide synthases)"


name: LC3 binds ATG7 dimer (Rattus norvegicus)


name: H2O + NADP(+) + nitrosobenzene = H(+) + NADPH + nitrobenzene


name: cytokinin riboside 5'-monophosphate phosphoribohydrolase activity


name: a 2-iminocarboxylate + H2O <=> a 2-oxocarboxylate + NH4(+)


name: a ubiquinone + ethanol => a ubiquinol + acetaldehyde


name: butanoyl-CoA + H(+) + NADH => butanal + CoA + NAD(+)


name: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = 3-((4-bromophenyl)sulfanyl)-2-oxopropanoate + L-glutamate


name: ATP + glycerol 2-phosphate(out) + H2O <=> ADP + glycerol 2-phosphate(in) + H(+) + phosphate


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Rattus norvegicus)


name: (S)-3-(imidazol-5-yl)lactate + NAD(+) => 3-(imidazol-5-yl)pyruvate + H(+) + NADH


name: H(+)(in) + L-histidine(in) + L-ornithine(out) = H(+)(out) + L-histidine(out) + L-ornithine(in)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Canis familiaris)


name: Autocatalytic activation of MMP1 (Homo sapiens)


name: RUNX3 binds SRC (Drosophila melanogaster)


name: (2S)-2-aminobutanoate + 3-(4-hydroxyphenyl)pyruvate => 2-oxobutanoate + L-tyrosine


name: Degradation of ubiquitinated beta catenin by the proteasome (Canis familiaris)


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Mus musculus)


name: hydrolase activity, acting on acid halide bonds


name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)


name: (5S)-hydroperoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate = (5S,6S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: POU5F1 (OCT4), SOX2, NANOG bind the TSC22D1 promoter (Homo sapiens)


name: 9H-carbazole + H(+) + NADPH + O2 = 2'-aminobiphenyl-2,3-diol + NADP(+)


name: CREBBP, EP300 acetylates NFE2L2 (Sus scrofa)


name: P2X1-mediated entry of Ca++ from plasma (Danio rerio)


name: SREBP1A,1C,2 translocates to the nucleus (Sus scrofa)


name: Activation of Ca2+ activated Potassium channels with small conductance (Dictyostelium discoideum)


name: a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH => a long-chain fatty acyl-CoA + n CO2 + n CoA + H2O + 2n NADP(+)


name: A + 2 ADP + H(+) + NH4(+) + 2 phosphate => AH2 + 2 ATP + H2O + hydroxylamine


name: 7,8-dihydromonapterin 3'-triphosphate + 3 H2O = 7,8-dihydromonapterin + 2 H(+) + 3 phosphate


name: PIAS1 SUMOylates SATB1 with SUMO1 (Bos taurus)


name: (+)-lariciresinol + H(+) + NADPH => (-)-secoisolariciresinol + NADP(+)


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Mus musculus)


name: Melanocortin receptors bind melanocortins (Bos taurus)


name: p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane (Drosophila melanogaster)


name: 5-deoxy-D-ribose + ATP => 5-deoxy-alpha-D-ribose 1-phosphate + ADP + H(+)


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Mus musculus)


name: ATG10 dissociates from ATG12:ATG5 (Rattus norvegicus)


name: DPP4(1-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Rattus norvegicus)


name: hexadecan-1-ol + O2 = H2O2 + hexadecanal


name: H2O + limonene 1,2-epoxide + NAD(+) => (4R)-limonene + H(+) + NADH + O2


name: Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)


name: (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate => [5-(aminomethyl)furan-3-yl]methyl diphosphate + gamma-L-glutamyltyramine


name: AXIN is ubiquitinated by SMURF2 (Danio rerio)


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Rattus norvegicus)


name: (+)-kolavelool + S-adenosyl-L-methionine <=> (+)-O-methylkolavelool + H(+) + S-adenosyl-L-homocysteine


name: 3-ethylmalate + CoA + H(+) => butanoyl-CoA + glyoxylate + H2O


name: chloride + L-tyrosine + NADP(+) <=> 3-chloro-L-tyrosine + NADPH


name: SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Mus musculus)


name: nocamycin I + S-adenosyl-L-homocysteine => nocamycin E + S-adenosyl-L-methionine


name: a triacylglycerol + all-trans-retinol => a 1,3-diacylglycerol + an all-trans-retinyl ester


name: 3-phenylpropylamine + pyruvate <=> 3-phenylpropanal + L-alanine


name: C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + L-glutamate => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + H2O


name: chrysobactin transmembrane transporter activity


name: DARC  is a non-specific receptor for many chemokines (Bos taurus)


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Homo sapiens)


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Xenopus tropicalis)


name: RHOD GAPs stimulate RHOD GTPase activity (Homo sapiens)


name: Recruitment of SHC1 is mediated by Y593 of the common beta chain (Rattus norvegicus)


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Schizosaccharomyces pombe)


name: Dynamin is recruited to the gap junction plaque (Homo sapiens)


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Mus musculus)


name: p-S215 FOXO1 positively regulates RAG gene expression  (Homo sapiens)


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Mus musculus)


name: (S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O


name: (2E,6E)-farnesyl diphosphate + H2O => diphosphate + kunzeaol


name: chloride + FADH2 + L-tryptophan + O2 = 6-chloro-L-tryptophan + FAD + 2 H2O


name: 12-hydroperoxy-(10E,14Z)-eicosadienoate => (11Z,14Z)-eicosadienoate + O2


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H(+) + phosphocholine


name: a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) <=> a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Gallus gallus)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Dictyostelium discoideum)


name: HCCS inserts heme into cytochrome c (Saccharomyces cerevisiae)


name: 1-haloalkane + H2O => a halide anion + a primary alcohol + H(+)


name: trans-4-hydroxy-L-prolyl-[protein] + UDP-beta-L-arabinofuranose => H(+) + O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-prolyl-[protein] + UDP


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H(+) + UDP


name: AH2 + Latia luciferin + 2 O2 => A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin


name: SUMOylation of MKL1 with SUMO1 (Rattus norvegicus)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Mus musculus)


name: BACH1 translocates from the cytosol to the nucleoplasm (Xenopus tropicalis)


name: A4GALT transfers galactose to LacCer (Canis familiaris)


name: an alcohol + H(+) + sn-glycerol 3-phosphate => a sn-glycero-3-phosphodiester + H2O


name: carboxyspermidine dehydrogenase II activity


name: MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Rattus norvegicus)


name: galactitol + NADP(+) <=> D-galactose + H(+) + NADPH


name: Syndecans 2, (4) bind TGFB1 (Bos taurus)


name: (8S)-8-amino-7-oxononanoate + L-lysine = (7R,8S)-7,8-diammoniononanoate + (S)-2-amino-6-oxohexanoate


name: H2O + mevastatin => (S)-2-methylbutanoate + compactin diol lactone + H(+)


name: Phosphorylation of IKKs complex mediated by MEKK1 (Gallus gallus)


name: Disassociation of Processive Complex and Completed Telomere End (Sus scrofa)


name: 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + H(+) + S-adenosyl-L-homocysteine => 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Sus scrofa)


name: precorrin-6B + 2 S-adenosyl-L-methionine = CO2 + 3 H(+) + precorrin-8X + 2 S-adenosyl-L-homocysteine


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Sus scrofa)


name: "non-specific serine/threonine protein kinase"


name: ATP + phosphate + pyruvate <=> AMP + diphosphate + H(+) + phosphoenolpyruvate


name: octadecanoyl-CoA + serotonin <=> CoA + H(+) + N-octadecanoyl-serotonin


name: 3-nitropropanoate + NADP(+) => 3-nitroacrylate + H(+) + NADPH


name: PIP3 binds to RhoA and activates it (Homo sapiens)


name: ADP + ATP <=> adenosine 5'-tetraphosphate + AMP


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: "benzil reductase [(S)-benzoin forming]"


name: (R)-malate(in) + 2 H(+)(in) => (R)-malate(out) + 2 H(+)(out)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Rattus norvegicus)


name: benzyl acetate + H2O + NADP(+) => H(+) + NADPH + O2 + phenylacetone


name: Further sulfation on galactose residues produces KSPG (Homo sapiens)


name: (10E)-octadecenoate + H2O = 10-hydroxyoctadecanoate


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)


name: D-aspartate(out) + H(+)(out) + K(+)(in) + 3 Na(+)(out) = D-aspartate(in) + H(+)(in) + K(+)(out) + 3 Na(+)(in)


name: a dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine => a dolichyl N-acetyl-alpha-D-glucosaminyl phosphate + UDP


name: all-trans-zeaxanthin + O2 => (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal


name: Association of DFF with alpha:beta importin (Canis familiaris)


name: SEMA4D interacts with CD45 (Rattus norvegicus)


name: A + D-proline => 1-pyrroline-2-carboxylate + AH2


name: holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Sus scrofa)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Saccharomyces cerevisiae)


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate => alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-galctosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Bos taurus)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Canis familiaris)


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Xenopus tropicalis)


name: (2S)-naringenin 4',7-dimethyl ether + O2 + reduced [NADPH--hemoprotein reductase] <=> (2S)-carthamidin-4',7-dimethyl ether + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SUMOylation of NCOA1 with SUMO1 (Gallus gallus)


name: NAD(+) + UDP-alpha-D-glucuronate => CO2 + NADH + UDP-beta-L-threo-pentopyranos-4-ulose


name: Cho is phosphorylated to PCho by CHK dimer (Bos taurus)


name: CHEK1 phosphorylates TP53 (Mus musculus)


name: UDP-alpha-D-galactose(in) + UMP(out) <=> UDP-alpha-D-galactose(out) + UMP(in)


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Rattus norvegicus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = diphosphate + somaliensene A


name: RHOA:GTP binds ROCK, activating it (Danio rerio)


name: ZnT8 transports zinc into the Golgi apparatus (Dictyostelium discoideum)


name: Binding of the MCC complex to the APC/C complex (Gallus gallus)


name: A + H2O + isoquinoline = AH2 + isoquinolin-1(2H)-one


name: RHOC binds effectors at the plasma membrane (Bos taurus)


name: FMNH2 + O2 + sulfoacetate = FMN + glyoxylate + 2 H(+) + H2O + sulfite


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoserine + ethanolamine


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Gallus gallus)


name: (13E)-labda-7,13-dien-15-yl diphosphate = diphosphate + labda-7,13(16),14-triene


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Rattus norvegicus)


name: H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Gallus gallus)


name: 2,4,6-trichlorophenol + S-adenosyl-L-methionine => 2,4,6-trichloroanisole + S-adenosyl-L-homocysteine


name: NLRC5 binds IKBKB and CHUK (Rattus norvegicus)


name: 2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA


name: Assembly of EGFR complex in clathrin-coated vesicles (Homo sapiens)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Canis familiaris)


name: Recruitment of VAV and BTK to p-SLP-76 (Mus musculus)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Gallus gallus)


name: (S)-3-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O


name: LTA trimer binds TNFRSF1A,1B,14 (Sus scrofa)


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Canis familiaris)


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)


name: acetyl-CoA + dodecanoyl-CoA => 3-oxotetradecanoyl-CoA + CoA


name: H2O + L-asparagine + O2 <=> 2-oxosuccinamate + H2O2 + NH4(+)


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Homo sapiens)


name: 1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + octanoate


name: 2-deoxy-alpha-L-fucosylaclacinomycin S + dTDP + H(+) => aclacinomycin S + dTDP-2-deoxy-beta-L-fucose


name: CXADR binds to AMICA1 (Canis familiaris)


name: 1-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + 1-O-alkyl-sn-glycero-3-phosphoethanolamine = 1-O-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-O-alkyl-sn-glycero-3-phosphocholine


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O => 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate


name: GST dimers cleave AZA to 6MP (Dictyostelium discoideum)


name: Phosphorylated FOXO1A is excluded from the nucleus (Rattus norvegicus)


name: RGS proteins bind GNB5 and CCT/TRiC (Sus scrofa)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Drosophila melanogaster)


name: Autocleavage of ESPL1 (Separase) (Plasmodium falciparum)


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Rattus norvegicus)


name: sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP (Gallus gallus)


name: Two FPP molecules dimerize to form presqualene diphosphate (Rattus norvegicus)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Homo sapiens)


name: (11R)-carlactone + O2 + reduced [NADPH--hemoprotein reductase] <=> (11R)-19-hydroxycarlactone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP => 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose


name: (S)-2-benzylsuccinate + succinyl-CoA => (S)-2-benzylsuccinyl-CoA + succinate


name: CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Homo sapiens)


name: ATXN3 family cleave Ub chains (Plasmodium falciparum)


name: 1alpha-hydroxyandrost-4-ene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => androst-4-ene-3,17-dione + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + H2O <=> a 5'-end phospho-adenosine in mRNA + 2 H(+) + N(7)-methyl-GDP


name: ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA (Danio rerio)


name: BTN2A2 binds T cell surface (Homo sapiens)


name: 2-oxoglutarate + CO2 => (S)-oxalosuccinate + H(+)


name: H(+)(in) + inosine(in) = H(+)(out) + inosine(out)


name: PC is exchanged with PI by PITPNB (Drosophila melanogaster)


name: holo-[peptidyl-carrier protein] + L-seryl-5'-AMP = AMP + L-seryl-[peptidyl-carrier protein]


name: FGFR4 binds to FGF (Caenorhabditis elegans)


name: ribosomal protein S6 glutamate-glutamate ligase activity


name: Factor Xa inhibitors bind Va:Xa (Mus musculus)


name: galactosamine transmembrane transporter activity


name: 3-oxoadipate + succinyl-CoA = 3-oxoadipyl-CoA + succinate


name: PERP binds desmosomes (Caenorhabditis elegans)


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Mus musculus)


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Canis familiaris)


name: factor VIIIa + factor IXa -> factor VIIIa:factor IXa (Homo sapiens)


name: ABC7, mABC1 and mABC2 mediate heme transport (Homo sapiens)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Schizosaccharomyces pombe)


name: L,L-cystathionine = 2-aminobut-2-enoate + L-cysteine


name: GEF dissociates from DRheb-GTP (Drosophila melanogaster)


name: ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A <=> ADP + alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: BLM mediates dissolution of double Holliday junction (Homo sapiens)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Bos taurus)


name: Interleukin-1 family are secreted (Rattus norvegicus)


name: D-arabinose 5-phosphate <=> D-glyceraldehyde 3-phosphate + glycolaldehyde


name: TFAP2C homodimer binds MYC and KDM5B (Bos taurus)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Sus scrofa)


name: GLUT7 and GLUT11 transport glucose and fructose (Xenopus tropicalis)


name: acetate + ATP + holo-[citrate lyase ACP] => acetyl-[citrate lyase ACP] + AMP + diphosphate


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + H(+)(in) = (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + H(+)(out)


name: a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2


name: 5alpha-cholest-8-en-3beta-ol + NADP(+) = H(+) + NADPH + zymosterol


name: ASP-3026- resistant ALK mutants don't bind ASP-3026 (Homo sapiens)


name: Dissociation of the TP:G13 complex (Bos taurus)


name: FOXG1 binds FOXO:SMAD complexes (Homo sapiens)


name: SERPINA6 binds PREDN (Drosophila melanogaster)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADPH = all-trans-lycopaoctaene + 2 diphosphate + NADP(+)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Rattus norvegicus)


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Schizosaccharomyces pombe)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)


name: H2O + L-valine + NADP(+) = 3-methyl-2-oxobutanoate + H(+) + NADPH + NH4(+)


name: The Ligand:GPCR:Gq complex dissociates (Homo sapiens)


name: RNA Pol II initiates transcription from damaged DNA template (Mus musculus)


name: H2O + trithionate <=> H(+) + sulfate + thiosulfate


name: AH2 + diphosphate + nonaflavuxanthin => A + all-trans-lycopene + dimethylallyl diphosphate + H2O


name: (-)-4'-methoxycyclopeptine + 2-oxoglutarate + O2 => (Z)-4'-methoxydehydrocyclopeptine + CO2 + H2O + succinate


name: Activated FGFR1 phosphorylates SHC1 (Danio rerio)


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Canis familiaris)


name: 1-acyl-sn-glycero-3-phospho-N-acyl-L-serine + a fatty acid + H(+) => 1,2-diacyl-sn-glycero-3-phospho-N-acyl-L-serine + H2O


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Gallus gallus)


name: [thioredoxin]-dithiol + arsenate + H(+) <=> [thioredoxin]-disulfide + arsenite + H2O


name: Activation of Rho by LARG and PDZ-RhoGEF (Xenopus tropicalis)


name: acetaldehyde + desmosterol => (24R,24(1)R)-fucosterol epoxide


name: CO2 + CoA + olivetol => 3,5,7-trioxododecanoyl-CoA


name: hexanoyl-CoA + L-seryl-[protein] => CoA + O-hexanoyl-L-seryl-[protein]


name: Defective CYP11A1 does not cleave 20a,22b-DHCHOL (Homo sapiens)


name: N-(9Z-octadecenoyl) ethanolamine + phosphate => H2O + N-(9Z-octadecenoyl)-ethanolamine phosphate


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+) => (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + NADPH


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Mus musculus)


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O = 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + choline + H(+)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Gallus gallus)


name: H(+) + NADP(+) + 2 reduced [4Fe-4S]-[ferredoxin] = NADPH + 2 oxidized [4Fe-4S]-[ferredoxin]


name: hederagenin + O2 + reduced [NADPH--hemoprotein reductase] = gypsogenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + N,N-dimethylaniline + NADPH + O2 <=> H2O + N,N-dimethylaniline N-oxide + NADP(+)


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Rattus norvegicus)


name: diphosphate + dUMP + NH4(+) => dCTP + 2 H2O


name: Fgr may phosphorylate p38 MAPK (Gallus gallus)


name: (1'S,5'R)-5'-hydroxyaverantin + NAD(+) <=> (S)-5'-oxoaverantin + 2 H(+) + NADH


name: RHOD translocates to the Golgi membrane (Sus scrofa)


name: (+)-alpha-tocopherol + H(+) + S-adenosyl-L-homocysteine => gamma-tocopherol + S-adenosyl-L-methionine


name: C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+) => 2 (S)-methylmalonyl-CoA + 10 H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 3 malonyl-CoA + 5 NADPH


name: Association of HMGB1/HMGB2 with chromatin (Plasmodium falciparum)


name: BTN2A2 binds T cell surface (Sus scrofa)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Caenorhabditis elegans)


name: H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine <=> H(+) + N-acyl-15-methylhexadecasphing-4-enine + phosphocholine


name: 3-dehydroquinate + H(+) + NADH + NH4(+) => 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+)


name: 2 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol => 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a cardiolipin


name: SGTA binds Tail-anchored protein (Bos taurus)


name: CHPF,CHSY3 transfer GalNAc to chondroitin (Homo sapiens)


name: UCKL1 phosphorylates urindine, cytidine (Caenorhabditis elegans)


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Homo sapiens)


name: CO2 + gibberellin A20 + H2O => gibberellin A19 + H(+) + O2


name: AKT1 binds eNOS complex via HSP90 (Gallus gallus)


name: 2 H(+) + N-(2-carboxyethyl)putrescine + NADH => H2O + N-(4-aminobutyl)-3-aminopropanal + NAD(+)


name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Homo sapiens)


name: RUNX3 binds SMAD3 and SMAD4 (Bos taurus)


name: GTSE1 translocates to the nucleus (Canis familiaris)


name: H2O + trihexadecanoylglycerol => dihexadecanoylglycerol + H(+) + hexadecanoate


name: cortisol + O2 + reduced [NADPH--hemoprotein reductase] => 6beta-hydroxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Drosophila melanogaster)


name: Cross-linking of FCGRIIIA with IgG-coated Ag (Sus scrofa)


name: Degradation of ubiquitinated SMAD3 (Mus musculus)


name: JNK phosphorylates BIM, BAD and other targets (Canis familiaris)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Canis familiaris)


name: PIP3 binds to RhoA and activates it (Rattus norvegicus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Mus musculus)


name: ATP + H2O + L-cystine(out) => ADP + H(+) + L-cystine(in) + phosphate


name: Membrane proteases cleave Profilaggrin producing Filaggrin (Canis familiaris)


name: SLC22A1 transports Cipro into renal cell (Drosophila melanogaster)


name: L-arginine(out) + L-histidine(in) => L-arginine(in) + L-histidine(out)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 chloride + 2 FADH2 + 2 O2 = (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 FAD + 4 H2O


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Rattus norvegicus)


name: a 2,3-diacyl-sn-glycerol + an acyl-CoA => a triacyl-sn-glycerol + CoA


name: (3R)-hydroxy-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA <=> (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H2O


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Mus musculus)


name: 2 H2 + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 3 H(+) + NADH + 2 reduced [2Fe-2S]-[ferredoxin]


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Caenorhabditis elegans)


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Sus scrofa)


name: C20 sphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (4R)-hydroxyeicosasphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate => 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H(+) + UDP


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Dictyostelium discoideum)


name: SUMOylation of MDC1 with SUMO1 (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Dictyostelium discoideum)


name: FA anion diffuses laterally to UCP (Xenopus tropicalis)


name: N-hydroxy-L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: AH2 + S-methyl-1-thio-D-xylulose 5-phosphate = 1-deoxy-D-xylulose 5-phosphate + A + methanethiol


name: a ribonucleotidyl-ribonucleotide-RNA + H2O <=> a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+)


name: Ubiquitination of NEMO by TRAF6 (Canis familiaris)


name: a 3-hydroxy-fatty acyl-CoA => a (2E)-enoyl-CoA + H2O


name: Joining of adjacent Okazaki fragments of the C-strand (Rattus norvegicus)


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Rattus norvegicus)


name: glycine + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + sarcosine


name: cephalosporin C + CoA => acetyl-CoA + deacetylcephalosporin C


name: P4HB:4-Hyp collagen propeptides dissociates (Gallus gallus)


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Mus musculus)


name: (E)-4-coumaroyl-CoA + H(+) + NADPH => (E)-4-coumaraldehyde + CoA + NADP(+)


name: eicosanoate + sphing-4-enine => H2O + N-eicosanoyl-sphing-4-enine


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Dictyostelium discoideum)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Homo sapiens)


name: CES1 hydrolyses sacubitril to sacubitrilat (Rattus norvegicus)


name: O-atom dealkylation of dextromethorphan (Homo sapiens)


name: SCD desaturates ST-CoA to OLE-CoA (Dictyostelium discoideum)


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Gallus gallus)


name: NAD(+) + testosterone <=> androst-4-ene-3,17-dione + H(+) + NADH


name: (2E,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H(+) + NADPH => (11Z,14Z,17Z)-eicosatrienoyl-CoA + NADP(+)


name: glyoxylate + L-aspartate => glycine + oxaloacetate


name: Internalization of gap junction plaques (Homo sapiens)


name: NICD2 binds RBPJ and MAML in the nucleus (Gallus gallus)


name: p-DAPP1 (p-BAM32) binds PLCG2 (Gallus gallus)


name: Dephosphorylation of CK2-modified condensin I (Rattus norvegicus)


name: ABC7, mABC1 and mABC2 mediate heme transport (Canis familiaris)


name: Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity (Homo sapiens)


name: CK2:FACT phosphorylates TP53 (Drosophila melanogaster)


name: Association of procollagen type XVIII (Mus musculus)


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Homo sapiens)


name: Inactivation of APC/C via CDC20 sequestration (Xenopus tropicalis)


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Gallus gallus)


name: (6S)-5,6,7,8-tetrahydrofolate + vanillate = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 3,4-dihydroxybenzoate


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Drosophila melanogaster)


name: D-ribulose 5-phosphate <=> ribose 5-phosphate (Homo sapiens)


name: glutaryl-CoA + H2O <=> CoA + glutarate + H(+)


name: VEGFA-165 dimer binds VEGFA inhibitors (Sus scrofa)


name: FMN-N(5)-peroxide + thymine => (Z)-2-methylureidoacrylate + FMN-N(5)-oxide + 2 H(+)


name: shikimate 3-dehydrogenase (NADP+) activity


name: coelenterazine + O2 => CO2 + coelenteramide + hnu


name: PLK1 phosphorylates OPTN (Xenopus tropicalis)


name: Prolactin receptor is internalized (Homo sapiens)


name: p-S MAPK6 phosphorylates NCOA3 (Canis familiaris)


name: 2-oxoglutarate + dihydroclavaminate + O2 = clavaminate + CO2 + H2O + succinate


name: gypsogenin + O2 + reduced [NADPH--hemoprotein reductase] = gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Gallus gallus)


name: RBKS phosphorylates ribose to R5P (Dictyostelium discoideum)


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Homo sapiens)


name: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H(+) + O2 = aureusidin 6-O-beta-glucoside + H2O


name: ICMT methylates S-Farn RAS proteins (Drosophila melanogaster)


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)


name: D-erythrose 4-phosphate + H2O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH


name: "N-terminal methionine N(alpha)-acetyltransferase NatC"


name: Expression of EPHA4 in presomitic mesoderm (Homo sapiens)


name: 2 ATP + GTP => 3',3',3'-cAAG + 3 diphosphate


name: RCHY1 monoubiquitinates POLH (Canis familiaris)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Mus musculus)


name: Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA (Bos taurus)


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Gallus gallus)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Mus musculus)


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Bos taurus)


name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate (Homo sapiens)


name: Activation of ATP sensitive Potassium channels in muscle cells (Sus scrofa)


name: JMJD6 demethylates MeR3-histone H3 (Mus musculus)


name: 20S,23-dihydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 20S,23,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: dCDP + H(+) + phosphoenolpyruvate => dCTP + pyruvate


name: ATP + glycoursodeoxycholate(in) + H2O <=> ADP + glycoursodeoxycholate(out) + H(+) + phosphate


name: ABCA4 mediates atRAL transport (Mus musculus)


name: Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) (Sus scrofa)


name: H(+) + hnu + octanoate <=> CO2 + heptane


name: Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex (Homo sapiens)


name: Importin-8 binds AGO2:miRNA (Canis familiaris)


name: 2-acyl LPC is acylated to PC by LPCAT (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid IIA = a 2-acyl-sn-glycero-3-phosphocholine + a lipid IIB


name: AGK:Mg2+ phosphorylates MAG, DAG (Xenopus tropicalis)


name: an N-acylsphingoid base 1-phosphate(in) <=> an N-acylsphingoid base 1-phosphate(out)


name: chlorophyllide a + NADP(+) => 3,8-divinyl chlorophyllide a + H(+) + NADPH


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc (Rattus norvegicus)


name: 3-aminopropanal + H2O2 + N-acetylputrescine => H2O + N(1)-acetylspermidine + O2


name: 3'-phosphoadenylyl sulfate + 3beta-androst-5-en-17-one 3-O-(beta-D-glucuronate) => 3beta-androst-5-en-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: vanadium ion transmembrane transporter activity


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Xenopus tropicalis)


name: Migfilin interacts with VASP (Caenorhabditis elegans)


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Mus musculus)


name: [(1->4)-beta-D-mannosyl](n) + phosphate <=> [(1->4)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate


name: Dopa is oxidized to dopaquinone by TYR (Dictyostelium discoideum)


name: 1,4-benzoquinone + H(+) + NADH <=> hydroquinone + NAD(+)


name: RNA demethylases demethylate N6-methyladenosine RNA (Canis familiaris)


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Mus musculus)


name: Homodimerization of VEGF proteins (Bos taurus)


name: a 5'-end dephospho-2'-deoxyribonucleoside-DNA + phosphate => a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H2O


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Plasmodium falciparum)


name: Caspase mediated cleavage of alpha-II-Fodrin (Drosophila melanogaster)


name: Methylation of GMP-cap by RNA Methyltransferase (Saccharomyces cerevisiae)


name: GPLD1 hydrolyses GPI-anchors from proteins (Sus scrofa)


name: TBK1 is phosphorylated within the activated TLR4 complex (Gallus gallus)


name: a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 3' overhang single-stranded DNA endodeoxyribonuclease activity


name: RAC3 GAPs stimulate RAC3 GTPase activity (Danio rerio)


name: 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + H(+) + NADPH + O2 = 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + 2 H2O + NADP(+)


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Canis familiaris)


name: 2-oxoglutarate + 6-acetamido-3-aminohexanoate <=> 6-acetamido-3-oxohexanoate + L-glutamate


name: AXIN is ubiquitinated by SMURF2 (Mus musculus)


name: 5-fluorouridine + ATP = 5-fluorouridine 5'-phosphate + ADP + H(+)


name: 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 24 H(+) + 8 malonyl-CoA + 16 NADPH => 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+)


name: HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Danio rerio)


name: L-glutamine(in) + L-valine(out) + Na(+)(out) <=> L-glutamine(out) + L-valine(in) + Na(+)(in)


name: H2O + O2 + tryptamine = H2O2 + indole-3-acetaldehyde + NH4(+)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Gallus gallus)


name: ADP + gamma-L-glutamylspermine + H(+) + phosphate => ATP + L-glutamate + spermine


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Homo sapiens)


name: H(+) + L-homoserine + tRNA(Lys) => H2O + L-homoseryl-tRNA(Lys)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Drosophila melanogaster)


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Xenopus tropicalis)


name: dATP + H2O <=> 2-deoxyribose 5-triphosphate + adenine


name: decanoyl-[ACP] + H2O => decanoate + H(+) + holo-[ACP]


name: PTPN11 binds p-Y759-IL6ST (Xenopus tropicalis)


name: 9-cis-retinyl tetradecanoate + CoA => 9-cis-retinol + tetradecanoyl-CoA


name: New CENPA-containing nucleosomes are deposited at the centromere (Gallus gallus)


name: N-terminal L-aspartyl-[protein] + NH4(+) => H(+) + H2O + N-terminal L-asparaginyl-[protein]


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + malonyl-CoA => (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA + CO2 + CoA


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Mus musculus)


name: P2Y14 receptor can bind to UDP-glucose (Xenopus tropicalis)


name: 13-epi-manool + diphosphate => (+)-copalyl diphosphate + H2O


name: RLBP1:11cRAL dissociates (Dictyostelium discoideum)


name: acetate + L-lysine => H2O + N-acetyl-L-lysine


name: 2,2-dihydroxyspirilloxanthin => 2-oxospirilloxanthin + H2O


name: cyclic pyranopterin phosphate + diphosphate => (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate = (-)-delta-cadinene + diphosphate


name: p-3Y-SHC1 dissociates from IGF1R (Sus scrofa)


name: BCL2 binds BCL2 antagonists (Gallus gallus)


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Sus scrofa)


name: PREX2 binds PTEN and inhibits it (Xenopus tropicalis)


name: GAB1 phosphorylation by EGFR kinase (Gallus gallus)


name: H2O + N(8)-acetylspermidine + O2 = 4-acetamidobutanal + H2O2 + propane-1,3-diamine


name: CO2 + succinate + trans-4-hydroxy-L-prolyl-[Skp1 protein] => 2-oxoglutarate + L-prolyl-[Skp1 protein] + O2


name: Phosphorylation of ARM by CKIalpha (Drosophila melanogaster)


name: Branching and elongation of mother and daughter filaments (Danio rerio)


name: 2 H(+) + 2 phosphate + UMP => 2 H2O + UTP


name: 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA => 1-dodecanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: 15-methylhexadecasphing-4-enine + a fatty acyl-CoA => CoA + H(+) + N-acyl-15-methylhexadecasphing-4-enine


name: allodeoxycholate + beta-muricholoyl-CoA => allodeoxycholoyl-CoA + beta-muricholate


name: HGSNAT oligomer acetylates Heparan chain(1) (Sus scrofa)


name: LIG1 binds APEX1 and PCNA at SSB (Mus musculus)


name: SCF-FBXL7 ubiquitinates AURKA (Schizosaccharomyces pombe)


name: Phosphorylation and activation of VAV2/VAV3 by SYK (Rattus norvegicus)


name: Binding of RRN3 to RNA Polymerase I (Schizosaccharomyces pombe)


name: (R)-pantoate + NADP(+) => 2-dehydropantoate + H(+) + NADPH


name: acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-4-O-acetylneuraminate


name: Flipping of the N-glycan precursor to inside the ER (Homo sapiens)


name: 2,4'-dihydroxyacetophenone + O2 <=> 4-hydroxybenzoate + formate + 2 H(+)


name: RHOH binds effectors at the plasma membrane (Dictyostelium discoideum)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Gallus gallus)


name: (9Z)-hexadecenoyl-[ACP] + L-lysyl-[protein] <=> H(+) + holo-[ACP] + N(6)-[(9Z)-hexadecenoyl]-L-lysyl-[protein]


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Bos taurus)


name: Addition of the third nucleotide on the nascent transcript (Dictyostelium discoideum)


name: H2O + O2 + retinal = H(+) + H2O2 + retinoate


name: 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: pppA(2'-5')pG = 3',2'-cGAMP + diphosphate


name: 2 Fe(III)-[cytochrome c] + L-gulono-1,4-lactone => 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate


name: Surface deployment of platelet alpha granule membrane components (Gallus gallus)


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Rattus norvegicus)


name: ATP + beta-alanine + L-histidine <=> ADP + carnosine + H(+) + phosphate


name: TP53BP1 recruits DCLRE1C to ATM (Bos taurus)


name: ESR1:ESTG binds to proximal and distal regions of the CTSD promoter (Homo sapiens)


name: GP1b signaling involves c-Src (Sus scrofa)


name: Na(+)(in) + urate(out) => Na(+)(out) + urate(in)


name: N,N',N''-triacetylchitotriose + O2 = H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone


name: Activated TrkA receptor internalizes to endosomes (Canis familiaris)


name: SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Danio rerio)


name: (9Z)-hexadecenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA


name: (2Z,6Z)-farnesyl diphosphate <=> (-)-alpha-cedrene + diphosphate


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Bos taurus)


name: an acyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + an acyl-4'-phosphopantetheine + 2 H(+)


name: AH2 + androst-4-ene-3,17-dione + O2 => A + H2O + testololactone


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a medium chain fatty acid + ATP + CoA <=> a medium-chain fatty acyl-CoA + AMP + diphosphate


name: H2O + sphing-4-enine-phosphocholine => H(+) + phosphocholine + sphing-4-enine


name: Addition of the third nucleotide on the nascent transcript (Sus scrofa)


name: NCOA1 recruits EP300 to TGFA promoter (Bos taurus)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Rattus norvegicus)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Rattus norvegicus)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: indole-3-pyruvate + L-phenylalanine => 3-phenylpyruvate + L-tryptophan


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Xenopus tropicalis)


name: Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Homo sapiens)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-glutaminyl-[protein] => acetyl-CoA + N-terminal L-methionyl-L-glutaminyl-[protein]


name: 1-propanol + NADP(+) <=> H(+) + NADPH + propanal


name: H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] <=> L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate


name: CTP + D-ribitol 5-phosphate + H(+) <=> CDP-L-ribitol + diphosphate


name: RNF8 and RNF168 ubiquitinate H2AFX (Mus musculus)


name: (20S)-protopanaxatriol + UDP-alpha-D-glucose => (20S)-ginsenoside Rh1 + H(+) + UDP


name: PNPLA4 hydrolyzes TAG (Xenopus tropicalis)


name: ASIC trimers:H+ transport extracellular Na+ to cytosol (Caenorhabditis elegans)


name: H2O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Gallus gallus)


name: Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Gallus gallus)


name: (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(out) <=> (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(in)


name: a ribonucleotide in rRNA + S-adenosyl-L-methionine <=> a 2'-O-methylribonucleotide in rRNA + H(+) + S-adenosyl-L-homocysteine


name: ACO2 isomerizes citrate (Caenorhabditis elegans)


name: 2-dehydro-3-deoxy-D-arabinonate + NAD(+) <=> 5-hydroxy-2,4-dioxopentanoate + H(+) + NADH


name: PTPN3 dephosphorylates EPS15 (Homo sapiens)


name: glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Homo sapiens)


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Xenopus tropicalis)


name: 3'-N-debenzoyltaxol + benzoyl-CoA <=> CoA + H(+) + taxol


name: 5-O-[(E)-caffeoyl]-D-quinate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + trans-5-O-(4-coumaroyl)-D-quinate


name: 5-dehydroepisterol + 2 Fe(III)-[cytochrome b5] + 2 H2O => episterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Schizosaccharomyces pombe)


name: IL34 dimer binds SDC1 (Xenopus tropicalis)


name: a fatty acid + taurine => an N-fatty acyl-taurine + H2O


name: 2-oxoglutarate + an N(1)-ethyl-2'-deoxyadenosine in single-stranded DNA + O2 => a 2'-deoxyadenosine in single-stranded DNA + acetaldehyde + CO2 + H(+) + succinate


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Bos taurus)


name: H(+) + malonyl-[ACP] + propanoyl-CoA = 3-oxopentanoyl-[ACP] + CO2 + CoA


name: 26Sproteasome degrades K48polyUb-NIK (Mus musculus)


name: L-methionine + tetrahydropteroyltri-L-glutamate => 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine


name: GLB1 hydrolyses a glycosaminoglycan (Homo sapiens)


name: UBXN1 binds BRCA1:BARD1 heterodimer (Canis familiaris)


name: glyoxylate + L-methionine <=> 4-methylsulfanyl-2-oxobutanoate + glycine


name: (9Z)-heptadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z)-heptadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Formation of the MLL4 complex (Homo sapiens)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Rattus norvegicus)


name: Recruitment of PLCgamma to membrane (Mus musculus)


name: an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose => a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + H(+) + UDP


name: 1,2,3-tripropanoylglycerol + H2O = dipropanoylglycerol + H(+) + propanoate


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Rattus norvegicus)


name: NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity


name: H2O + NADP(+) <=> ADP-D-ribose 2'-phosphate + H(+) + nicotinamide


name: AH2 + N-acyl-15-methylhexadecasphinganine + O2 => A + 2 H2O + N-acyl-15-methylhexadecasphing-4-enine


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)


name: LARG activation by G alpha 12/13 (Caenorhabditis elegans)


name: Beta-catenin translocates to the nucleus (Mus musculus)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 bromide + 3 FADH2 + 3 O2 <=> (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 FAD + 6 H2O


name: 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA => (9Z)-octadecenoyl-CoA + 1-O-hexadecylglycerol


name: SREBP1A,1C,2:Importin beta-1 dissociates (Homo sapiens)


name: Autophosphorylation of PAK (Mus musculus)


name: (S)-carvone + H(+) + NADH => (1R,5S)-carveol + NAD(+)


name: CoA + glycocholate + H(+) => choloyl-CoA + glycine


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Rattus norvegicus)


name: FPR2 binds FPR2 ligands (Rattus norvegicus)


name: MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex (Homo sapiens)


name: TP53 family members bind the CASP1 gene (Homo sapiens)


name: a 1,2-saturated acyl-CoA + an acyl-CoA + H2O => an (R)-2-alkyl-3-oxoalkanoate + 2 CoA + H(+)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Bos taurus)


name: Addition of the third nucleotide on the nascent transcript (Bos taurus)


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Danio rerio)


name: 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H(+) + 2 H2O + phthalate => 2 H2O2 + Reactive Blue 5


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Mus musculus)


name: [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) = [TtuB sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: Cleavage of ERBB4m80 by gamma-scretase complex (Homo sapiens)


name: H2O + NADH <=> AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Rattus norvegicus)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Rattus norvegicus)


name: Formation of Processive Complex (Homo sapiens)


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Bos taurus)


name: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Drosophila melanogaster)


name: Bile salts and acids bind ALB (Homo sapiens)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Drosophila melanogaster)


name: C3d-complexed antigen binds to complement receptor (Sus scrofa)


name: Synthesis of GAG polyprotein (Homo sapiens)


name: 3-(3-methylsulfanyl)propylmalate <=> 2-(2-methylsulfanyl)propylmaleate + H2O


name: n adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate + n H(+) => n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Homo sapiens)


name: N-hexanoyl-sphing-4-enine-1-phosphocholine <=> choline + N-(hexanoyl)-sphing-4-enine-1,3-cyclic phosphate


name: H(+) + L-ribulose + NADH => L-arabinitol + NAD(+)


name: a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+) => a 1,2-diacyl-sn-glycerol + ATP


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Mus musculus)


name: (2-aminoethyl)phosphonate + 2-oxoglutarate + O2 <=> (1R)-(2-amino-1-hydroxyethyl)phosphonate + CO2 + succinate


name: ATPase synthesizes ATP (Drosophila melanogaster)


name: TRAF6 is auto-ubiquitinated (Rattus norvegicus)


name: di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate => di-trans,octa-cis-undecaprenyl diphosphate + H2O


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Mus musculus)


name: ALDHs oxidise atRAL to atRA (Bos taurus)


name: 4',7-dihydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => 4',7,8-trihydroxyflavone + S-adenosyl-L-methionine


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: ZnT8 transports zinc into the Golgi apparatus (Sus scrofa)


name: 2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 2'-hydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Homo sapiens)


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Canis familiaris)


name: 3-hydroxyindolin-2-one + NADP(+) => H(+) + isatin + NADPH


name: alpha-D-mannopyranose + beta-D-mannopyranosyl-(1->2)-D-mannopyranose => beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp + H2O


name: Activated protein C:PROCR binds F2R (Homo sapiens)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Canis familiaris)


name: a ganglioside GM3 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD3 + CMP + H(+)


name: (19E)-geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + NADPH


name: 6-O-alpha-D-glucopyranosyl-D-fructose + H2O <=> alpha-D-glucose + D-fructose


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Mus musculus)


name: Two FPP molecules dimerize to form presqualene diphosphate (Sus scrofa)


name: Formation of DSIF complex  (Schizosaccharomyces pombe)


name: L-cystine(in) + L-glutamate(out) => L-cystine(out) + L-glutamate(in)


name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Dictyostelium discoideum)


name: NEUROG3-dependent synthesis of PAX4 protein (Homo sapiens)


name: L-cysteine + succinate => hydrogen sulfide + O-succinyl-L-serine


name: HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Dictyostelium discoideum)


name: eburicol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 14-demethyleburicol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: n a quinone + n H(+) + n hydrogen sulfide <=> n a quinol + n sulfur


name: Unwinding DNA for the nascent transcript (Homo sapiens)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-(O-farnesylgeranyl)glycerol 1-phosphate


name: ABCA7:Apo1A-mediated phospholipid efflux (Mus musculus)


name: 5-formyltetrahydrofolate transmembrane transporter activity


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Caenorhabditis elegans)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)


name: (1R,2S,4R)-borneol + NAD(+) <=> (1R,4R)-camphor + H(+) + NADH


name: Formation of the IGF:IGFBP3:ALS complex (Danio rerio)


name: 2-methyloctadecanoyl-CoA + H2O = 2-methyloctadecanoate + CoA + H(+)


name: a percarboxylic acid + H2O => a carboxylate + H(+) + H2O2


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 <=> CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate


name: RNF41 binds neuregulin-activated ERBB3 (Bos taurus)


name: PICALM binds R-SNAREs (Caenorhabditis elegans)


name: (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+) => (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADPH


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Canis familiaris)


name: 2-methyl-3-oxobutanoyl-CoA + CoA => acetyl-CoA + propanoyl-CoA


name: H(+) + N(4)-aminopropylspermidine + S-methyl-5'-thioadenosine => S-adenosyl 3-(methylsulfanyl)propylamine + spermidine


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Mus musculus)


name: PRKN binds p-S-Ub:MOM proteins (Saccharomyces cerevisiae)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Rattus norvegicus)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Schizosaccharomyces pombe)


name: an N-(ultra-long-chain-acyl)-sphingoid base + CoA + H(+) => a sphingoid base + an ultra-long-chain fatty acyl-CoA


name: Reduction of desmosterol to cholesterol (Xenopus tropicalis)


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Caenorhabditis elegans)


name: 16alpha,17alpha-dihydroxypregnenolone + O2 + reduced [NADPH--hemoprotein reductase] = 3beta,16alpha-dihydroxy-androst-5-en-17-one + acetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Nuclear DUSPs dephosphorylate MAPKs (Canis familiaris)


name: Loading of claspin onto DNA during replication origin firing (Rattus norvegicus)


name: Interleukin-12 binds Interleukin-12 receptor (Rattus norvegicus)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + dodecanoyl-[ACP] <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + holo-[ACP]


name: (2E,6E)-farnesyl diphosphate = (+)-beta-chamigrene + diphosphate


name: PRLR binds SCF beta-TrCP complex (Rattus norvegicus)


name: 12-epi-hapalindole U => 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole


name: dihydrochelirubine + H(+) + O2 => chelirubine + H2O2


name: Cleavage of C3 by C3 convertases (Danio rerio)


name: G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Mus musculus)


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Sus scrofa)


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Schizosaccharomyces pombe)


name: Glycosylation of ENV polyprotein (Homo sapiens)


name: EP400 binds CDKN1A promoter (Rattus norvegicus)


name: 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + CoA => (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA


name: MASTL (GWL) phosphorylates ARPP19 (Drosophila melanogaster)


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Mus musculus)


name: 8 A + a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid => a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 8 AH2


name: Caspase-mediated cleavage of E-Cadherin (Rattus norvegicus)


name: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Exocytosis of tertiary granule lumen proteins (Xenopus tropicalis)


name: RBKS phosphorylates ribose to R5P (Canis familiaris)


name: a 4,5-saturated-(2E)-enoyl-CoA + NADP(+) => a (2E,4Z)-dienoyl-CoA + H(+) + NADPH


name: Formation of dehydro-lysinonorleucine cross-links (Xenopus tropicalis)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Danio rerio)


name: holo-[peptidyl-carrier protein] + L-arginyl-AMP = AMP + H(+) + L-arginyl-[peptidyl-carrier protein]


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Xenopus tropicalis)


name: DDIT4 binds 14-3-3 dimer (Xenopus tropicalis)


name: H2O + tritetradecanoylglycerol => 2,3-ditetradecanoyl-sn-glycerol + H(+) + tetradecanoate


name: VWF variant does not bind GPIb:IX:V (Homo sapiens)


name: CD28 homodimer binds B7-1 homodimer (Canis familiaris)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Canis familiaris)


name: Casein kinase II phosphorylates PTEN (Homo sapiens)


name: Phenol can form a sulfate conjugate (Xenopus tropicalis)


name: (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 <=> 3beta-hydroxy-beta-cyclocitral + crocetin dialdehyde


name: (2S)-naringenin 4',7-dimethyl ether + H(+) + S-adenosyl-L-homocysteine => (2S)-sakuranetin + S-adenosyl-L-methionine


name: PAK1-3 autophosphorylates (Xenopus tropicalis)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 => (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O


name: Hh C-terminal fragments are degraded by the proteasome (Homo sapiens)


name: 4-hydroxyphenylacetonitrile + O2 + reduced [NADPH--hemoprotein reductase] = (S)-4-hydroxymandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Mevalonate-5-phosphate is further phosphorylated. (Drosophila melanogaster)


name: ent-sandaracopimara-8(14),15-diene + O2 + reduced [NADPH--hemoprotein reductase] => ent-sandaracopimaradien-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ALDH2 transforms GTN to NO (Saccharomyces cerevisiae)


name: Fibulin-1 and -2 bind fibronectin (Rattus norvegicus)


name: glutathione(in) + taurocholate(out) => glutathione(out) + taurocholate(in)


name: Release of platelet cytosolic components (Caenorhabditis elegans)


name: 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + 2 H(+) + NADPH => D-glucosamine 6-phosphate + NADP(+)


name: L-threonine => 2-aminobut-2-enoate + H2O