name: H2O + N-formylmethanofuran <=> formate + methanofuran


name: an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Homo sapiens)


name: ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA (Canis familiaris)


name: all-trans-zeaxanthin + 2 UDP-alpha-D-glucose = 2 H(+) + 2 UDP + zeaxanthin bis(beta-D-glucoside)


name: Cleavage of Procaspase-3 by the apoptosome (Canis familiaris)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Mus musculus)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Sus scrofa)


name: 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + CO2 + CoA => (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + H(+) + malonyl-CoA


name: TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 (Homo sapiens)


name: I-Smad competes with Co-Smad for R-Smad1/5/8 (Bos taurus)


name: 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(+) => 15-oxoprostaglandin E2 + H(+) + NADH


name: cis-2,3-dihydrodiol DDT dehydrogenase activity


name: 3-oxosphinganine + octadecanoyl-CoA => CoA + H(+) + N-octadecanoyl-3-oxosphinganine


name: c-FOS activation by phospho ERK1/2 (Bos taurus)


name: LIPs hydrolyse TG to DAG and RCOOH (Danio rerio)


name: beta-D-glucuronate + NAD(+) => D-glucaro-1,5-lactone + H(+) + NADH


name: IL3 stimulation induces Vav binding to Tec kinase (Bos taurus)


name: SCF:FBXL7 binds AURKA (Plasmodium falciparum)


name: ATP + H2O + indoxyl sulfate(in) => ADP + H(+) + indoxyl sulfate(out) + phosphate


name: TGFBR3 binding to ARRB1/2 (Canis familiaris)


name: FFAR1 binds fatty acids (Rattus norvegicus)


name: RBP3 regulates the transport of atROL from ROS to RPE (Sus scrofa)


name: 10-hydroxy-(11S,12S)-epoxy- (5Z,8Z,14Z)-eicosatrienoate + H2O = (10,11S,12R)-trihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: VIP receptors bind VIP (Canis familiaris)


name: alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + UDP-N-acetyl-alpha-D-glucosamine => alpha-D-Man-(1->3)-[alpha-D-GlcNAc-(1->2)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + H(+) + UDP


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Sus scrofa)


name: cortisol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 18-hydroxycortisol + H2O + 2 oxidized [adrenodoxin]


name: YWHAE dimer binds phosphorylated DENND1 proteins (Rattus norvegicus)


name: p-STAT5 dissociates from the receptor complex (Mus musculus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Mus musculus)


name: [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose => [(1->4)-alpha-D-glucosyl](n+1) + ADP + H(+)


name: H2O + N(2)-benzoyl-D-arginine-4-nitroanilide => 4-nitroaniline + H(+) + N(2)-benzoyl-D-arginine


name: NAGLU hydrolyses heparan chain(2) (Dictyostelium discoideum)


name: NEIL3 recognizes and binds to spiroiminodihydantoin (Homo sapiens)


name: PGM1:Mg2+ isomerises G6P to G1P (Drosophila melanogaster)


name: sphinganine 1-phosphate = hexadecanal + phosphoethanolamine


name: CYPs hydroxylate DHA to 14(R)-HDHA (Homo sapiens)


name: maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) (Canis familiaris)


name: 3-dehydro-4-methylzymosterol + CO2 + NADPH => 4beta-methylzymosterol-4alpha-carboxylate + NADP(+)


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Rattus norvegicus)


name: Phosphorylation of PLCgamma by PDGFR (Homo sapiens)


name: PARN deadenylates mRNA (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoylglycerol <=> 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: 3-hydroxybenzyl alcohol + acetyl-CoA = 3-hydroxy-benzyl acetate + CoA


name: E-cadherin degradation by ADAM10, ADAM15 (Gallus gallus)


name: 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol + CO2 + methylamine => carbofuran + H(+) + H2O


name: TGN-lysosomal vesicle coat assembly (Homo sapiens)


name: 1-O-(9Z)-octadecenoyl-2-O-acetyl-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 2-acetyl-sn-glycero-3-phosphocholine + H(+)


name: mitochondrial ribosomal large subunit rRNA binding


name: Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL (Homo sapiens)


name: (E)-non-2-enal + H2O + NAD(+) <=> (E)-non-2-enoate + 2 H(+) + NADH


name: p-BMAL1:p-CLOCK,NPAS2 binds F7 gene (Homo sapiens)


name: Degradation of ubiquitinated SMAD3 (Danio rerio)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Dictyostelium discoideum)


name: 3'-phosphoadenylyl sulfate + H2O <=> adenosine 5'-phosphosulfate + phosphate


name: N-atom dealkylation of caffeine (Rattus norvegicus)


name: PIDD1 associates with CRADD (Mus musculus)


name: Recruitment of GAB2 to PM and FCERI by binding to GRB2 (Homo sapiens)


name: WWOX binds ERBB4s80 (Drosophila melanogaster)


name: (3R)-3-isocyanylbutanoyl-AMP + holo-[ACP] = (3R)-3-isocyanylbutanoyl-[ACP] + AMP + H(+)


name: p-6Y-SYK phosphorylates BLNK (SLP65) (Homo sapiens)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Rattus norvegicus)


name: Butyrylcholinesterase hydrolyzes acyl Ghrelin (Canis familiaris)


name: Cis-Heterodimerization of nephrin and KIRREL (Mus musculus)


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Rattus norvegicus)


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Canis familiaris)


name: atROL binds to RBP2 (Caenorhabditis elegans)


name: Association of procollagen type XXII (Rattus norvegicus)


name: mRNA9a is translated to Nucleoprotein (Homo sapiens)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Homo sapiens)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Danio rerio)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Schizosaccharomyces pombe)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Danio rerio)


name: Conversion of C2 into C2a and C2b (Xenopus tropicalis)


name: Ub,pS335,S338,T NFE2L2 is degraded (Bos taurus)


name: ADP + daunorubicin(out) + H(+) + phosphate => ATP + daunorubicin(in) + H2O


name: nicotinamide + S-adenosyl-L-methionine = 1-methylnicotinamide + S-adenosyl-L-homocysteine


name: (2S)-2-amino-4-deoxychorismate => anthranilate + H(+) + pyruvate


name: HEXB cleaves the terminal GalNAc from DS (Mus musculus)


name: O2 + reduced [NADPH--hemoprotein reductase] + solavetivol => H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + solavetivone


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Rattus norvegicus)


name: hydrolase activity, acting on glycosyl bonds


name: G-protein alpha subunit is inactivated (Mus musculus)


name: HHAT palmitoylates Hh N-terminal fragment (Gallus gallus)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + CO2 + CoA


name: Removal of siRNA passenger strand (Gallus gallus)


name: OGG1beta translocates to mitochondria (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+) <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: (8S)-8-amino-7-oxononanoate + CO2 + L-lysyl-[protein] = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 2 H(+)


name: Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65) (Homo sapiens)


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Canis familiaris)


name: GTP:coenzyme F420 guanyltransferase activity


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Free APC/C phosphorylated by Plk1 (Xenopus tropicalis)


name: ethylnitronate + O2 <=> acetaldehyde + chemical entity + H(+) + nitrite


name: O2 + reduced [NADPH--hemoprotein reductase] + xanthotoxin <=> 5-hydroxyxanthotoxin + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Beta-catenin binds SOX proteins (Danio rerio)


name: peptidoglycan cross-bridge peptide endopeptidase activity


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Mus musculus)


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Caenorhabditis elegans)


name: acetyl-CoA + N-terminal L-prolyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-prolyl-[protein]


name: all-trans-undecaprenol + ATP => ADP + all-trans-undecaprenyl phosphate + H(+)


name: RETSAT reduces atROL to at-13,14-dhROL (Homo sapiens)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)


name: 1-O-alkyl-3-acylglycerol + an acyl-CoA => 1-O-alkyl-2,3-diacylglycerol + CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + UDP-alpha-D-galactose <=> 1,2-di-(9Z-octadecenoyl)-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP


name: 3-hydroxy-3-methylglutarate + malonyl-CoA <=> (3S)-hydroxy-3-methylglutaryl-CoA + malonate


name: DCC interaction with Ezrin (Homo sapiens)


name: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) => 2,3-dihydroxybenzoate + H(+) + NADH


name: 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Rattus norvegicus)


name: an N-(fatty acyl)-L-tryptophan + H2O => a fatty acid + L-tryptophan


name: (2E)-butenoyl-CoA + H2O => (2R)-hydroxybutanoyl-CoA


name: 2 2-oxoglutarate + 2 O2 + preaustinoid A <=> berkeleytrione + 2 CO2 + H2O + 2 succinate


name: cyclobis-(1->3)-alpha-D-isomaltosyl + H2O = alpha-isomaltosyl-(1->3)-isomaltose


name: phosphate + solabiose <=> alpha-D-glucose 1-phosphate + D-galactose


name: (9Z)-octadecenoate + H2O => (R)-10-hydroxyoctadecanoate


name: sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Bos taurus)


name: SFTPs translocate from extracellular region to clathrin-coated vesicle (Canis familiaris)


name: NAD-dependent histone decrotonylase activity


name: carnosine + H2O => beta-alanine + L-histidine


name: an N-acyl-D-glucosamine => an N-acyl-D-mannosamine


name: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Caenorhabditis elegans)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Xenopus tropicalis)


name: PAK1 phosphorylates myosin phosphatase (Sus scrofa)


name: Activated FGFR2:pFRS binds GRB2:SOS1 (Canis familiaris)


name: deoxycholoyl-CoA + NAD(+) => 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + H(+) + NADH


name: (20S)-ginsenoside C-K + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + O2 + reduced [NADPH--hemoprotein reductase]


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Rattus norvegicus)


name: a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H(+) => a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Bos taurus)


name: Duplex miRNA is loaded into Argonaute (Caenorhabditis elegans)


name: ADP-D-ribose + phosphate => ADP-alpha-D-ribose 1''-phosphate + H2O


name: (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) <=> 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: dimethylallyl diphosphate + 3 isopentenyl diphosphate => 3 diphosphate + nerylneryl diphosphate


name: PP2A dephosphorylates p-RHO to RHO (Caenorhabditis elegans)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Mus musculus)


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Mus musculus)


name: PRKAA2 regulated nuclear export of NFE2L2 (Sus scrofa)


name: (4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + A + acetone + H(+) + H2O => 4-farnesyl-3,5-dihydroxy-6-methylphthalide + AH2 + 2 O2


name: ATP + L-threonyl-[Fas-activated protein] <=> ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein]


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Mus musculus)


name: eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Canis familiaris)


name: 2 Na(+)(out) + propanoate(out) = 2 Na(+)(in) + propanoate(in)


name: MIA2 and MIA3 load procollagen VII into COPII vesicles (Mus musculus)


name: CSNK1D phosphorylates SEC23 (Schizosaccharomyces pombe)


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Canis familiaris)


name: CDO binds promyogenic cadherins (Gallus gallus)


name: ATP + L-glutamyl-tRNA(Gln) <=> 5-phosphooxy-L-glutamyl-tRNA(Gln) + ADP


name: Transport of the export-competent mRNP complex through the NPC (Gallus gallus)


name: H2O + phosphoethanolamine => acetaldehyde + NH4(+) + phosphate


name: (2E)-geranyl diphosphate = beta-myrcene + diphosphate


name: glutathione + thiosulfate = H(+) + S-sulfanylglutathione + sulfite


name: WWP2 ubiquitinates NOTCH3 (Gallus gallus)


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Gallus gallus)


name: ABCB11 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)


name: Na+/H+ exchanger transport (at cell membrane) (Mus musculus)


name: dopamine + hexadecanoyl-CoA => CoA + H(+) + N-hexadecanoyl-dopamine


name: a ubiquinone + reduced [electron-transfer flavoprotein] <=> a ubiquinol + H(+) + oxidized [electron-transfer flavoprotein]


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Bos taurus)


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Mus musculus)


name: ZIP8 mediates zinc influx into cells (Sus scrofa)


name: NMT1/2 transfer MYS to GNAT1 (Saccharomyces cerevisiae)


name: a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH


name: RHOGDI binds to and sequesters RHO1:GDP complex to the cytosol (Drosophila melanogaster)


name: SARS-CoV-2 3a binds to STING (Homo sapiens)


name: p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Danio rerio)


name: an N-acetylarylalkylamine + H2O <=> acetate + an aralkylamine


name: a 5,6-dihydrouridine in mRNA + NAD(+) <=> a uridine in mRNA + H(+) + NADH


name: acetone + 2 ATP + 3 H2O + hydrogencarbonate => acetoacetate + 2 AMP + 4 H(+) + 4 phosphate


name: an N-(fatty acyl)-L-leucine + H2O => a fatty acid + L-leucine


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) (Xenopus tropicalis)


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Dictyostelium discoideum)


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Canis familiaris)


name: asperaculane G + O2 + reduced [NADPH--hemoprotein reductase] = aculene D + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: RHOT2 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: Calmodulin activates Cam-PDE 1 (Plasmodium falciparum)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Homo sapiens)


name: an N-(fatty acyl)-L-methionine + H2O => a fatty acid + L-methionine


name: a menaquinone(in) + dimethyl sulfide(out) + H2O(out) => a menaquinol(in) + dimethyl sulfoxide(out)


name: S-adenosyl-L-methionine + uridine(47) in tRNA(Phe) <=> 3-[(3S)-3-amino-3-carboxypropyl]uridine(47) in tRNA(Phe) + H(+) + S-methyl-5'-thioadenosine


name: (3R)-hydroxyoctadecanoyl-CoA => (2E)-octadecenoyl-CoA + H2O


name: GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Homo sapiens)


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Canis familiaris)


name: glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ (Gallus gallus)


name: H(+) + hexadecanoyl-CoA + malonyl-[ACP] = 3-oxooctadecanoyl-[ACP] + CO2 + CoA


name: DEGS1 dehydrogenates dihydroceramide (Schizosaccharomyces pombe)


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Mus musculus)


name: Plk1-mediated phosphorylation of Nlp (Gallus gallus)


name: H(+) + hercynine + S-adenosyl-L-homocysteine => N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-methionine


name: 1,2,3-trioctanoylglycerol + H2O => dioctanoylglycerol + H(+) + octanoate


name: PLA1A hydrolyses PS to 2-acyl LPS (Rattus norvegicus)


name: [Glu(-Cys)](n+1)-Gly + glycine => [Glu(-Cys)](n)-Gly + glutathione + H(+)


name: PHGDH tetramer dehydrogenates 3PG (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Bos taurus)


name: TFIIH binds GG-NER site to form a verification complex (Gallus gallus)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Mus musculus)


name: PARVB interacts with Alpha-actinin (Gallus gallus)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Bos taurus)


name: D-galactono-1,5-lactone + H(+) + NADPH => D-galactose + NADP(+)


name: formate + N-terminal L-methionyl-[peptide] => H2O + N-terminal N-formyl-L-methionyl-[peptide]


name: Autophosphorylation of PAK1,2,3 (Saccharomyces cerevisiae)


name: LUM (lumican) binds integrin alpha2beta1 (Mus musculus)


name: 3 3-oxopropanoate + 3 H(+) + H2O2 + 2 nitrate + nitrite => H2O + 3 O2 + 3 propionate 3-nitronate


name: Dephosphorylation of CK2-modified condensin I (Bos taurus)


name: cadaverine(in) + L-lysine(out) <=> cadaverine(out) + L-lysine(in)


name: 2 Na(+)(out) + taurohyocholate(out) = 2 Na(+)(in) + taurohyocholate(in)


name: Activated FGFR4 phosphorylates PPTN11 (Xenopus tropicalis)


name: (3R)-3-isocyanylbutanoate + ATP + H(+) = (3R)-3-isocyanylbutanoyl-AMP + diphosphate


name: Nectin-1:PVRL3 trans heterodimer formation (Gallus gallus)


name: (+)-copalyl diphosphate + H2O <=> (+)-copalol + diphosphate


name: USP13 deubiquitinates BECN1,USP10 (Homo sapiens)


name: ME1 tetramer decarboxylates OA to PYR (Bos taurus)


name: (2S,4S)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine => (2S)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: Cleavage of thymine by TDG glycosylase (Bos taurus)


name: mycophenolic acid O-acyl-beta-D-glucuronide + UDP => mycophenolate + UDP-alpha-D-glucuronate


name: CTDNEP1:CNEP1R1 dephosphorylates LPIN (Caenorhabditis elegans)


name: 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + H2O => beta-D-Gal-(1<->1')-Cer + H(+) + sulfate


name: AUF1 binds translation and heat shock proteins (Homo sapiens)


name: ATP + hydroxylamine + L-glutamate => ADP + L-glutamine hydroxamate + phosphate


name: H2O + NAD(+) + propanal => 2 H(+) + NADH + propanoate


name: (2E)-geranyl diphosphate => diphosphate + limonene


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Caenorhabditis elegans)


name: HBEGF-bound EGFR forms a heterodimer with GPNMB (Gallus gallus)


name: BIL:ALB scavenges O2.- (Xenopus tropicalis)


name: 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-seryl-[protein] + H(+) + UDP


name: ATP + daunorubicin(in) + H2O => ADP + daunorubicin(out) + H(+) + phosphate


name: PTPN1 and PTPN2 dephosphorylate MET (Canis familiaris)


name: ADP + H(+) + phospho-[DNA-directed RNA polymerase] => [DNA-directed RNA polymerase] + ATP


name: AKT1 phosphorylates eNOS (Drosophila melanogaster)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH


name: H2O + N-hydroxy-L-aspartate + NADP(+) => L-aspartate + NADPH + O2


name: Li(+)(in) + melibiose(in) => Li(+)(out) + melibiose(out)


name: (2E,9Z)-hexadecadienoyl-CoA + FADH2 => (9Z)-hexadecenoyl-CoA + FAD + H(+)


name: Elastin cross-linking by lysyl oxidase (Gallus gallus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Mus musculus)


name: D-xylono-1,4-lactone 5-phosphate + H2O => 5-phospho-D-xylonate + H(+)


name: tetrapeptide transmembrane transporter activity


name: UNC119B binds myristoylated proteins (Homo sapiens)


name: G6PC hydrolyzes G6P to Glc and Pi (liver) (Rattus norvegicus)


name: p-S585-IL3RB binds 14-3-3 proteins (Bos taurus)


name: Nuclear translocation of catalytic domain of Mst3 (Bos taurus)


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Bos taurus)


name: PON1,3 hydrolyse ATVL to ATV (Canis familiaris)


name: Formation of the NSL complex (Mus musculus)


name: Phosphorylation of MDM4 by ATM (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: NEIL3 cleaves spiroiminodihydantoin (Xenopus tropicalis)


name: flavanone 7-O-beta-D-glucoside + UDP-beta-L-rhamnose => flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] + H(+) + UDP


name: (+)-abscisic acid 8'-hydroxylase activity


name: adenine + dehypoxanthine futalosine => 6-amino-6-deoxyfutalosine + H2O


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Canis familiaris)


name: (9Z)-hexadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) => (9Z)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: PSIP1 binds MEN1 associated with MLL2 complex (Homo sapiens)


name: 3-oxobutanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxybutanoyl-[ACP] + NADP(+)


name: 7,8-dihydroneopterin + O2 = 7,8-dihydroxanthopterin + formate + glycolaldehyde + H(+)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Caenorhabditis elegans)


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Sus scrofa)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Bos taurus)


name: H(+) + oxidized [electron-transfer flavoprotein] + pentanoyl-CoA <=> (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 1,3-di-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-glycerol


name: GTP + pyruvate = GDP + H(+) + phosphoenolpyruvate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: FANCD2 deubiquitination by USP1:WDR48 (Canis familiaris)


name: anthranilate + malonyl-CoA = CoA + N-malonylanthranilate


name: LARG activation by G alpha 12/13 (Mus musculus)


name: CD22 binds itself to form homo-oligomers (Sus scrofa)


name: Activated type I receptor phosphorylates SMAD2/3 directly (Caenorhabditis elegans)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Caenorhabditis elegans)


name: phosphate + sucrose => H2O + sucrose 6(F)-phosphate


name: L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] => H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu)


name: P4HB forms mixed disulphides with Hh precursors (Bos taurus)


name: STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Bos taurus)


name: ADP(out) + FMN(in) => ADP(in) + FMN(out)


name: ATP(in) + CoA(in) + H(+)(out) + octadecanoate(out) = AMP(in) + diphosphate(in) + H(+)(in) + octadecanoyl-CoA(in)


name: dihydroprecondylocarpine acetate = acetate + catharanthine + H(+)


name: Recruitment of p190RhoGEF to p-FAK (Bos taurus)


name: (2Z,6Z)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate


name: (9Z)-octadecenoyl-CoA + 1-decanoylglycerol => 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Dictyostelium discoideum)


name: 1-butanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-hexadecyl-sn-glycero-3-phosphocholine => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Drosophila melanogaster)


name: CFTR transports Cl- from cytosol to extracellular region (Xenopus tropicalis)


name: B-WICH complex binds rDNA promoter (Homo sapiens)


name: BLT receptors can bind LTB4 (Sus scrofa)


name: RAC3 binds ER effectors (Canis familiaris)


name: [thioredoxin]-dithiol + NADP(+) <=> [thioredoxin]-disulfide + H(+) + NADPH


name: AH2 + androst-4-ene-3,17-dione + O2 <=> A + H2O + testololactone


name: SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Danio rerio)


name: Activated FGFR4 phosphorylates FRS2 (Gallus gallus)


name: Activation of Protein Kinase C novel isoforms (Saccharomyces cerevisiae)


name: chloride(out) + L-serine(out) + 2 Na(+)(out) <=> chloride(in) + L-serine(in) + 2 Na(+)(in)


name: Ubiquitinated Orc1 enters the cytosol (Xenopus tropicalis)


name: an N-acetyl-L-cysteine-S-conjugate + H2O = acetate + an S-substituted L-cysteine


name: Melatonin receptors can bind melatonin (Caenorhabditis elegans)


name: SERPINB13 binds cathepsin L (Homo sapiens)


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Bos taurus)


name: S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = H(+) + S-methyl-5'-thioadenosine + spermine


name: GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress (Homo sapiens)


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Canis familiaris)


name: Caspase mediated cleavage of alpha-II-Fodrin (Sus scrofa)


name: p-MAPKAPK3 phosphorylates BMI1 (Gallus gallus)


name: ATP + benzoate + CoA <=> AMP + benzoyl-CoA + diphosphate


name: Formation of soluble VTN:C5b-C9  (Sus scrofa)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Xenopus tropicalis)


name: gibberellin A34 + S-adenosyl-L-methionine => O-methyl gibberellin A34 + S-adenosyl-L-homocysteine


name: L-asparaginyl-[protein] + UDP-alpha-D-glucose => H(+) + N(4)-(beta-D-glucosyl)-L-asparaginyl-[protein] + UDP


name: Complement factor I complex formation (Xenopus tropicalis)


name: n H(+)(in) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(in) => n H(+)(out) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(out)


name: aspulvinone H + 2 diphosphate => aspulvinone E + 2 dimethylallyl diphosphate


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Sus scrofa)


name: HLA-A specific inhibitory MHC class I receptor activity


name: [thioredoxin]-disulfide + dADP + H2O <=> [thioredoxin]-dithiol + ADP


name: docosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 2-hydroxydocosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Bos taurus)


name: NADP(+) + nonan-2-one => (3E)-nonen-2-one + H(+) + NADPH


name: 4-methylphenol + H2O + 2 oxidized [azurin] = 4-hydroxybenzyl alcohol + 2 H(+) + 2 reduced [azurin]


name: oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor


name: Activation of JAK kinases (Homo sapiens)


name: MDM2 translocates to the nucleus (Canis familiaris)


name: (2Z,6Z)-farnesyl diphosphate + H2O = (6Z)-nerolidol + diphosphate


name: 11-cis-retinal + H(+) + NADH => 11-cis-retinol + NAD(+)


name: acetyl-CoA + S-(2-aminoethyl)-L-cysteine = CoA + H(+) + S-(2-acetamidoethyl)-L-cysteine


name: (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate => (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Xenopus tropicalis)


name: Glycoproteins with lesser folding defects get transported back to the ER and the CNX/CRT complex (Homo sapiens)


name: phycourobilin-L-cysteinyl(84)-[R-phycocyanin alpha-subunit] = (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[R-phycocyanin alpha-subunit]


name: "R-phycocyanin alpha-cysteine-84 phycourobilin lyase/isomerase"


name: CoA + glyoxylate + NADP(+) <=> H(+) + NADPH + oxalyl-CoA


name: n 3'-phosphoadenylyl sulfate + dermatan 4'-sulfate = n adenosine 3',5'-bisphosphate + dermatan 4',6'-bissulfate + n H(+)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Rattus norvegicus)


name: ABCA12 transports lipids from cytosol to extracellular region (Canis familiaris)


name: 3',3'-c-di-AMP + H2O <=> 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H(+)


name: 2,3-dimethylsuccinate(out) + 3 Na(+)(out) => 2,3-dimethylsuccinate(in) + 3 Na(+)(in)


name: Activated FGFR4 phosphorylates SHC1 (Xenopus tropicalis)


name: ADP + D-glucose => AMP + D-glucose 6-phosphate + H(+)


name: 4',7,8-trihydroxy-3'-methoxyflavone-7-olate + H(+) + S-adenosyl-L-homocysteine => 3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine


name: 3-hydroxyglutarate(out) + 3 Na(+)(out) => 3-hydroxyglutarate(in) + 3 Na(+)(in)


name: n adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate + 2 H(+) => n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate


name: Formation of the PCAF-ATAC complex (Gallus gallus)


name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Bos taurus)


name: TOPORS SUMOylates IKBKE with SUMO1 (Gallus gallus)


name: a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GD1c + CMP + H(+)


name: 1-deoxypentalenate + 2-oxoglutarate + O2 = 1-deoxy-11beta-hydroxypentalenate + CO2 + succinate


name: (S)-stylopine + S-adenosyl-L-methionine = (S)-cis-N-methylstylopine + S-adenosyl-L-homocysteine


name: D-xylono-1,4-lactone + H(+) + NADPH => D-xylofuranose + NADP(+)


name: carboxymethoxysuccinate => fumarate + glycolate


name: H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine


name: factor VII -> factor VIIa (Xenopus tropicalis)


name: MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB (Homo sapiens)


name: ERCC6 binds stalled RNA Pol II (Gallus gallus)


name: (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one + H(+) + NADPH => 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP(+)


name: 8-oxo-GTP + H2O <=> 8-oxo-GMP + diphosphate + H(+)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Danio rerio)


name: MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)


name: GDP-beta-L-fucose + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate = GDP + H(+) + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: snRNA Cap hypermethylation (Gallus gallus)


name: ATP + chloramphenicol(in) + H2O = ADP + chloramphenicol(out) + H(+) + phosphate


name: hexadecan-1-ol + NADP(+) = H(+) + hexadecanal + NADPH


name: PXLP-K56-SRR dimer deaminates D-Ser (Caenorhabditis elegans)


name: a phosphate monoester + H2O <=> an alcohol + phosphate


name: Activated FGFR4 phosphorylates FRS2 (Homo sapiens)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Bos taurus)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine => 4-methyl-2-oxopentanoate + L-kynurenine


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Caenorhabditis elegans)


name: A + H2O + N(6),N(6)-dimethyl-L-lysyl-[protein] <=> AH2 + formaldehyde + N(6)-methyl-L-lysyl-[protein]


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Sus scrofa)


name: a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL (Homo sapiens)


name: AH2 + cholesterol + O2 <=> 25-hydroxycholesterol + A + H2O


name: a sphingoid 1-phosphate + H2O = a sphingoid base + phosphate


name: CYP1B1 4-hydroxylates EST17b (Mus musculus)


name: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H(+) + phosphate


name: Cleavage of ethenoadenine by MPG glycosylase (Mus musculus)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: PAO:FAD oxidises NASPM to PTCN (Sus scrofa)


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Gallus gallus)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Danio rerio)


name: CoA + H(+) + N-hexadecanoylsphinga-(4E,8E)-dienine => hexadecanoyl-CoA + sphinga-(4E,8E)-dienine


name: an N-acyl-D-aspartate + H2O => a carboxylate + D-aspartate


name: Caspase-7 translocates to the nucleus (Gallus gallus)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Rattus norvegicus)


name: H2O + rhodomycin D = 10-carboxy-13-deoxycarminomycin + H(+) + methanol


name: NADH + nitrobenzene + O2 <=> catechol + NAD(+) + nitrite


name: XDH dehydrogenates hypoxanthine to form xanthine (Xenopus tropicalis)


name: maltodextrin transmembrane transporter activity


name: 3-oxoeicosanoyl-CoA + H(+) + NADH => (3R)-hydroxyeicosanoyl-CoA + NAD(+)


name: androst-4-ene-3,17-dione + H(+) + NADPH => 5beta-androstane-3,17-dione + NADP(+)


name: PARVB/Affixin interacts with alpha PIX (Gallus gallus)


name: 2 H(+)(in) + menaquinol-8 + nitrate = 2 H(+)(out) + H2O + menaquinone-8 + nitrite


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1,2-dihexanoylglycerol <=> 1,2-dihexanoyl-3-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + CoA


name: (S)-malate + UDP-N-acetyl-alpha-D-glucosamine => (S)-malyl N-acetyl-alpha-D-glucosaminide + H(+) + UDP


name: RHOBTB1 binds interacting proteins at the endosome membrane (Bos taurus)


name: H2O + L-canavanine <=> L-homoserine + N-hydroxyguanidine


name: Vesicular inhibitory amino acid transport (Caenorhabditis elegans)


name: NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Mus musculus)


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Bos taurus)


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Gallus gallus)


name: a nucleoside + phosphate => a nucleoside 5'-phosphate + H2O


name: H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate = GMP + GTP + 2 H(+)


name: Salvage - Sepiapterin is reduced to BH2 (Danio rerio)


name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Rattus norvegicus)


name: XYLB phosphorylates D-xylulose (Mus musculus)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O <=> a 5'-end phospho (purine-ribonucleoside) in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: 2 H(+) + 2 NADPH + octadecanoyl-CoA = CoA + 2 NADP(+) + octadecan-1-ol


name: D-glucose + FMN => alpha-D-glucose 1-phosphate + riboflavin


name: Active ALK phosphorylates JAK3 (Canis familiaris)


name: UGT1A3 lactonizes ATV to ATVL (Rattus norvegicus)


name: MAPK6 is degraded by the 26S proteasome (Caenorhabditis elegans)


name: butanoyl-CoA + phosphate => butanoyl phosphate + CoA


name: GBA1:SAPC hydrolyzes GlcCer (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol <=> 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Rattus norvegicus)


name: a ganglioside GT1c + H(+) + UDP => a ganglioside GT2 + UDP-alpha-D-galactose


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Canis familiaris)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Xenopus tropicalis)


name: SCD5 desaturates ST-CoA to OLE-CoA (Homo sapiens)


name: NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Canis familiaris)


name: TDO tetramer dioxygenates L-Trp to NFK (Mus musculus)


name: EXA4 is converted to EXC4 by LTC4S (Bos taurus)


name: ULK complex translocates to the ER (Rattus norvegicus)


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Danio rerio)


name: Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Drosophila melanogaster)


name: FADH2-C4alpha-hydroperoxide + H(+) + NADPH + rifamycin SV <=> FADH2 + H2O + NADP(+) + rifamycin SV hemiaminal


name: menadiol + 2 O2 => 2 H(+) + menadione + 2 superoxide


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol = a 1-acyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol


name: 1D-myo-inositol 1,4,5-trisphosphate + phosphate => 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O


name: Activated PCLG1 dissociates from NTRK3 (Bos taurus)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Gallus gallus)


name: Autocatalytic phosphorylation of FGFR1b (Danio rerio)


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate = CO2 + 2 H2O + NADP(+) + proviolacein


name: 13,14-dihydro-15-oxo-PGF2alpha + NADP(+) <=> 15-oxoprostaglandin F2alpha + H(+) + NADPH


name: COX10 transforms heme to heme O (Mus musculus)


name: TLR8 dimer binds TLR7, TLR8 ligands (Homo sapiens)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Mus musculus)


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Xenopus tropicalis)


name: chloride + FADH2 + melleolide F + O2 = 6'-chloromelleolide F + FAD + H(+) + 2 H2O


name: a quinol + 4 H(+)(out) + NAD(+) => a quinone + 5 H(+)(in) + NADH


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Caenorhabditis elegans)


name: Degradation of ubiquitinated SMAD3 (Gallus gallus)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Schizosaccharomyces pombe)


name: D-glyceraldehyde 3-phosphate => dihydroxyacetone phosphate


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+) => 2-dehydro-3-deoxy-D-gluconate + ATP


name: SFTPD binds with itself to form SFTPD 12mer (Danio rerio)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Drosophila melanogaster)


name: 4,4'-diaponeurosporenal + H2O + NAD(+) => 4,4'-diaponeurosporenoate + 2 H(+) + NADH


name: albendazole + H(+) + NADPH + O2 => albendazole S-oxide + H2O + NADP(+)


name: Insertion of MHC II:Ii complex in to the plasma membrane (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => avermitilol + diphosphate


name: (S)-dihydroorotate + NADP(+) => H(+) + NADPH + orotate


name: ATP + glutathione(in) + glycocholate(in) + H2O = ADP + glutathione(out) + glycocholate(out) + H(+) + phosphate


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Homo sapiens)


name: L-methionine(in) + S-methylmercury-L-cysteine(out) <=> L-methionine(out) + S-methylmercury-L-cysteine(in)


name: Axonal transport of NGF:Trk complexes (Canis familiaris)


name: Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Rattus norvegicus)


name: CO2 + H(+) + H2O + kaempferol + succinate => (2R,3R)-dihydrokaempferol + 2-oxoglutarate + O2


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Xenopus tropicalis)


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Gallus gallus)


name: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH


name: α2-agonists bind ADRA2A,B,C (Rattus norvegicus)


name: a medium chain fatty acid + ATP + H(+) = a medium-chain fatty acyl-AMP + diphosphate


name: IKKε (IKBKE) is ubiquitinated within the activated TLR3 complex (Homo sapiens)


name: Fibronectin degradation by ADAM8 (Sus scrofa)


name: 2 Fe(III)-[cytochrome c] + hydroxylamine => 2 Fe(II)-[cytochrome c] + 2 H(+) + nitroxyl


name: N-methyl-D-dopa + O2 => (3R)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2


name: 3-chloro-cis,cis-muconate + H(+) => (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate


name: (20S)-ginsenoside C-K + H(+) + UDP => (20S)-protopanaxadiol + UDP-alpha-D-glucose


name: UDP-alpha-D-glucuronate(out) + UDP-alpha-D-xylose(in) => UDP-alpha-D-glucuronate(in) + UDP-alpha-D-xylose(out)


name: 12-methyloctadecanoate + ATP + CoA <=> 12-methyloctadecanoyl-CoA + AMP + diphosphate


name: Formation of a Nef:ARF1:CD4 complex (Homo sapiens)


name: Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Mus musculus)


name: LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: ATP + H2O + leukotriene C4(in) => ADP + H(+) + leukotriene C4(out) + phosphate


name: RANBP2 SUMOylates PML with SUMO1 (Sus scrofa)


name: THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 (Gallus gallus)


name: acetyl-CoA + N-terminal L-cysteinyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-cysteinyl-[protein]


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Drosophila melanogaster)


name: AGO1,2:small RNA complexes interact with chromatin (Homo sapiens)


name: Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)


name: 5beta-androstane-3,17-dione + H(+) + NADPH => 3beta-hydroxy-5beta-androstane-17-one + NADP(+)


name: (3R)-3-hydroxy-L-arginyl-[RCC1 domain-containing protein] + CO2 + succinate => 2-oxoglutarate + L-arginyl-[RCC1 domain-containing protein] + O2


name: ZnT2 facilitates zinc vesicular sequestration (Homo sapiens)


name: 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide c + H(+) + L-methionine => a 7(1)-hydroxybacteriochlorophyllide c + H2O + S-adenosyl-L-methionine


name: H(+) + H2O + O-carbamoyl-L-serine => CO2 + 2 NH4(+) + pyruvate


name: STARD10 binds LPCAT1 and PC (Canis familiaris)


name: phosphate + solabiose => alpha-D-glucose 1-phosphate + D-galactose


name: (S)-malate(in) + citrate(out) => (S)-malate(out) + citrate(in)


name: 2 chloride(out) + glycine betaine(out) + 3 Na(+)(out) <=> 2 chloride(in) + glycine betaine(in) + 3 Na(+)(in)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: FN3K phosphorylates ketosamines (Caenorhabditis elegans)


name: MATS binds to HPO dimer (Drosophila melanogaster)


name: Degradation of newly synthesized ApoB-48 (Rattus norvegicus)


name: SHC1 binds P-ERBB4 isoform dimers (Rattus norvegicus)


name: G-protein coupled bile acid receptor binds lithocholic acid (Homo sapiens)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Schizosaccharomyces pombe)


name: SENP1,2,5 proteolytically process SUMO1 (Sus scrofa)


name: aldosterone + H(+) + NADPH = 5beta-dihydroaldosterone + NADP(+)


name: KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Caenorhabditis elegans)


name: HSF1 acetylation at Lys80 (Gallus gallus)


name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] (Gallus gallus)


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Sus scrofa)


name: FGFR1c binds to Klotho-bound FGF23 (Sus scrofa)


name: RHOB translocates to the endosome membrane (Gallus gallus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: Cleavage of Procaspase-3 by the apoptosome (Homo sapiens)


name: Activated FGFR2 binds PLCG1 (Canis familiaris)


name: ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Danio rerio)


name: HSPG2 (perlecan) binds alpha-dystroglycan (Homo sapiens)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Mus musculus)


name: L-lysyl-[glycine-cleavage complex H protein] + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => L-lysyl-[lipoyl-carrier protein] + N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein]


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Xenopus tropicalis)


name: Dimerized phospho-IRF3 migrates to the nucleus (Canis familiaris)


name: 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + H2O + NADP(+) => 2-methoxy-6-(all-trans-hexaprenyl)phenol + H(+) + NADPH + O2


name: saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity


name: 3-O-(5'-adenylyl)-L-threonyl-[protein] + H2O <=> AMP + H(+) + L-threonyl-[protein]


name: Translocation of activated BAX to the mitochondria (Sus scrofa)


name: Pancreatic proteases degrade TCN1:RCbl (Xenopus tropicalis)


name: 1-aci-nitro-2-(1H-indol-3-yl)ethane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (E)-(indol-3-yl)acetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase]


name: O2 + reduced [NADPH--hemoprotein reductase] + typhasterol = 7-oxatyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SFTPB,C, PC, PG translocate from lamellar body to extracellular region. (Gallus gallus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Schizosaccharomyces pombe)


name: an N-acyl-L-alpha-aminoacyl-tRNA + H2O <=> a tRNA + an N-acyl-L-amino acid + H(+)


name: purine nucleotide transmembrane transporter activity


name: NCOA1 binds ESR1:estrogen:TGFA gene (Rattus norvegicus)


name: [protein]-C-terminal-L-glutamine + H2O = [protein]-C-terminal-L-glutamate + NH4(+)


name: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> all-trans-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Bos taurus)


name: 2 Fe(II)-[cytochrome c] + 2 H(+) + N-methylmyosmine => (S)-nicotine + 2 Fe(III)-[cytochrome c]


name: ACY1:Zn2+ dimer hydrolyses mercapturic acids (Sus scrofa)


name: CHST14 transfers SO4(2-) to GalNAc in dermatan or DS (Danio rerio)


name: (3R)-3-methyl-D-ornithine + ATP + L-lysine = (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + ADP + H(+) + phosphate


name: (Z)-beta-farnesene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: NR3C2 binds fludrocortisone (Plasmodium falciparum)


name: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine => H(+) + N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine


name: ATP + N(6)-(D-erythrulosyl)-L-lysine <=> ADP + H(+) + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysine


name: nucleotide-sugar transmembrane transporter activity


name: Expression of ID4 in the nephric duct (Homo sapiens)


name: 4-methyl-2-oxopentanoate + H(+) => 3-methylbutanal + CO2


name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)


name: KCNJ11:ABCC9 binds nicorandil (Rattus norvegicus)


name: biphenyl-2-ol + H(+) + NADH + O2 => biphenyl-2,3-diol + H2O + NAD(+)


name: MBTPS2 (S2P) cleaves CREB3L3 (Gallus gallus)


name: Autophosphorylation of ALK fusions (Homo sapiens)


name: Association of procollagen type XIV (Dictyostelium discoideum)


name: SMURF2 monoubiquitinates SMAD3 (Drosophila melanogaster)


name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Sus scrofa)


name: Active ALK binds PLCG1 (Canis familiaris)


name: (2E)-nonenoyl-CoA + H2O2 => nonanoyl-CoA + O2


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Caenorhabditis elegans)


name: (Z)-3-ureidoacrylate + H2O => (Z)-3-aminoacrylate + carbamate + H(+)


name: REG3A,REG3G binds bacterial peptidoglycan (Drosophila melanogaster)


name: YOD1 binds VCP (Saccharomyces cerevisiae)


name: acetyl-CoA + 7 H(+) + 7 malonyl-CoA <=> 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + 7 CO2 + 8 CoA + 2 H2O


name: a globoside GalGb4Cer + H2O = an N-acyl-sphingoid base + beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc


name: CMP-N-acetyl-beta-neuraminate(in) + UMP(out) <=> CMP-N-acetyl-beta-neuraminate(out) + UMP(in)


name: goralatide + H2O = L-lysyl-L-proline + N-acetyl-L-seryl-L-aspartate


name: Closure of gap junction (Rattus norvegicus)


name: ERBB4s80 forms a complex with estrogen receptor ESR1 (Mus musculus)


name: PA is converted to CDP-DAG by CDS2 (Saccharomyces cerevisiae)


name: 1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] => 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein]


name: 1,6-didemethyltoxoflavin + S-adenosyl-L-methionine => H(+) + reumycin + S-adenosyl-L-homocysteine


name: ATPase-coupled nonpolar-amino acid transporter activity


name: RhBG mediates ammonium influx into kidney collecting duct cells (Rattus norvegicus)


name: Fgr may phosphorylate p38 MAPK (Caenorhabditis elegans)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Drosophila melanogaster)


name: 3-oxochol-4-en-22-oyl-CoA + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochol-4-en-22-oyl-CoA + H2O + NAD(+)


name: FRS2 is phosphorylated by active TrkA receptor (Canis familiaris)


name: TMEM55B translocates to the nucleus (Mus musculus)


name: 2-methylbutanamine + H2O + NADP(+) <=> 2-methylbutanal + H(+) + NADPH + NH4(+)


name: 2-hydroxy-3-methylnonanoyl-CoA + CO2 + succinate => 2-oxoglutarate + 3-methylnonanoyl-CoA + O2


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Canis familiaris)


name: NR3C2 binds fludrocortisone (Gallus gallus)


name: (3R)-hydroxy-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + NADP(+) => 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + H(+) + NADPH


name: 2-O-(long-chain fatty acyl)-3-O-mycolipenoyl-trehalose + CoA => 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + a mycolipenoyl-CoA


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Caenorhabditis elegans)


name: CBL-mediated ubiquitination of CIN85 (Rattus norvegicus)


name: (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+) => (+)-dehydrodiconiferyl acid + 2 a quinone + H2O


name: ent-7alpha-hydroxykaur-16-en-19-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => ent-kaur-16-en-19-oate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Canonical WNT signaling through the atypical receptor RYK (Rattus norvegicus)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Bos taurus)


name: Beta-catenin migrates to the nucleus (Rattus norvegicus)


name: CYTH proteins bind ARF1:GTP (Dictyostelium discoideum)


name: a ganglioside GT2 + H(+) + UDP => a ganglioside GT3 + UDP-N-acetyl-alpha-D-galactosamine


name: CYP4A11 12-hydroxylates DDCX (Canis familiaris)


name: NTP Binds Active Site of RNA Polymerase II (Gallus gallus)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Bos taurus)


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Dictyostelium discoideum)


name: PIAS3 SUMOylates PGR with SUMO1 (Homo sapiens)


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Gallus gallus)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Danio rerio)


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Gallus gallus)


name: Phosphorylated OPTN translocates to the nucleus (Homo sapiens)


name: [DsbD protein]-dithiol + [thioredoxin]-disulfide = [DsbD protein]-disulfide + [thioredoxin]-dithiol


name: Fibrillin-1 degradation by MMP14 (Homo sapiens)


name: 13-cis-retinoate + 2 H(+) + NADH => 13-cis-retinal + H2O + NAD(+)


name: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) <=> 5-amino-6-(D-ribitylamino)uracil + riboflavin


name: citrate(out) + 4 Na(+)(out) => citrate(in) + 4 Na(+)(in)


name: [Rab1 protein]-L-serine + CDP-choline <=> [Rab1 protein]-O-phosphocholine-L-serine + CMP + H(+)


name: GLUT7 and GLUT11 transport glucose and fructose (Canis familiaris)


name: (8S)-8-amino-7-oxononanoate + CO2 + CoA => 6-carboxyhexanoyl-CoA + H(+) + L-alanine


name: L-histidocholate + taurine => L-histidine + taurocholate


name: 3-hydroxyisopentadecanoyl-CoA + NADP(+) = 3-oxoisopentadecanoyl-CoA + H(+) + NADPH


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 11-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Rattus norvegicus)


name: AMPK (complex) phosphorylates ULK1 (complex) (Bos taurus)


name: Vamp8 associated secretory vesicle to plasma membrane transport (Caenorhabditis elegans)


name: LONP1 binds mitochondrial matrix proteins (Mus musculus)


name: (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) <=> catechol + H(+) + NADPH


name: 11-cis-retinol + NAD(+) = 11-cis-retinal + H(+) + NADH


name: 3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-seryl-[protein] + ATP => 3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phospho-alpha-D-mannosyl)-L-seryl-[protein] + ADP + H(+)


name: Activation of EPACs by cAMP (Homo sapiens)


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Homo sapiens)


name: alpha,alpha-trehalose + phosphate => alpha-D-glucose + alpha-D-glucose 1-phosphate


name: ADP + ATP => adenosine 3'-diphosphate,5'-diphosphate + AMP


name: PGRMC2:Hemes translocate to the nucleus (Rattus norvegicus)


name: a globoside NOR1 + UDP-N-acetyl-alpha-D-galactosamine => a globoside NORint + H(+) + UDP


name: Generation of CLIP from lip10 (Rattus norvegicus)


name: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Homo sapiens)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Homo sapiens)


name: G6PC hydrolyzes G6P to Glc and Pi (liver) (Drosophila melanogaster)


name: 2-MAG is transacylated to DAG by PNPLA2/3 (Drosophila melanogaster)


name: SPRY2 is serine phosphorylated in response to MAPK activation (Sus scrofa)


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Homo sapiens)


name: MITF-M dimer binds the BIRC7 promoter (Homo sapiens)


name: Activation of TWIK-related K+ channel (TREK) (Danio rerio)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CTP + H(+) => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Homo sapiens)


name: formate + H(+) + UTP <=> CO2 + dUTP + H2O


name: PLC-gamma1 hydrolyses PIP2 (Xenopus tropicalis)


name: a long-chain fatty acid + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] => a long-chain fatty acyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: decanoyl-AMP + diphosphate => ATP + decanoate + H(+)


name: D-glucose + D-glucose 6-phosphate => alpha,alpha-trehalose 6-phosphate + H2O


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Homo sapiens)


name: H(+)(out) + N-acetyl-L-aspartyl-L-glutamate(out) <=> H(+)(in) + N-acetyl-L-aspartyl-L-glutamate(in)


name: alpha-D-mannosyl-(1->4)-[3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose + GDP + H(+) => [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose + GDP-alpha-D-mannose


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Dictyostelium discoideum)


name: FMN + formaldehyde + 2 H(+) + H2O + sulfite => FMNH2 + methanesulfonate + O2


name: acetyl-CoA + trans-glutaconate <=> (2E)-glutaconyl-CoA + acetate


name: Formation of Cyclin E:Cdk2 complexes (Sus scrofa)


name: 16alpha-hydroxydehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) = 16alpha-hydroxydehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: Formation of the MCC complex (Sus scrofa)


name: ANKLE2 binds VRK1,(VRK2) (Caenorhabditis elegans)


name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Caenorhabditis elegans)


name: NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP (Gallus gallus)


name: RHOG binds effectors at the ER membrane (Canis familiaris)


name: malate(out) + 3 Na(+)(out) = malate(in) + 3 Na(+)(in)


name: GALNT3 transfers GalNAc to FGF23 (Sus scrofa)


name: angiotensin-(1-7) + H2O <=> angiotensin-(1-5) + L-histidyl-L-proline


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Gallus gallus)


name: a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a triacylglycerol => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Caenorhabditis elegans)


name: IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Gallus gallus)


name: S-adenosyl-L-methionine + xanthotoxol = H(+) + S-adenosyl-L-homocysteine + xanthotoxin


name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Canis familiaris)


name: guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine


name: all-trans-retinyl hexadecanoate + H2O => all-trans-retinol + H(+) + hexadecanoate


name: 5alpha-androst-1-ene-3,17-dione + A + H2O = 5alpha-androstan-1,3,17-trione + AH2


name: ADP + H(+) + streptomycin 3''-phosphate => ATP + streptomycin


name: 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP-alpha-D-glucose = 4-O-{[(2R)-2-alpha-D-glucosyl-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n H(+) + n UDP


name: dihydromacarpine + H(+) + O2 => H2O2 + macarpine


name: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Bos taurus)


name: NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates (Homo sapiens)


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Homo sapiens)


name: guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine <=> H(+) + N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine


name: kallikrein binds SERPING1 (Canis familiaris)


name: DENND3 exchanges GTP for GDP on RAB12 (Homo sapiens)


name: 2 H(+) + hexanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 5-hexenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PAK1-3 dimer disassociates (Canis familiaris)


name: E2F1 binds RAD51 gene promoter (Homo sapiens)


name: p38 MAPK phosphorylates PPARGC1A (Homo sapiens)


name: (22S)-22-hydroxycholestanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholestanol + O2 + reduced [NADPH--hemoprotein reductase]


name: SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC (Homo sapiens)


name: 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (1S)-1,25-dihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin]


name: acetate + D-glucose + H(+) => 6-acetyl-D-glucose + H2O


name: PRC1 SUMOylates CTBP1 with SUMO2,3 (Bos taurus)


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Mus musculus)


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Plasmodium falciparum)


name: an N(3)-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in mRNA + S-adenosyl-L-methionine


name: AMP + ATP <=> ADP + ADP [AK2] (Plasmodium falciparum)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Sus scrofa)


name: coelenterazine h dioxetanone => CO2 + excited coelenteramide h monoanion + H(+)


name: 2-hydroxybenzoyl-CoA + malonyl-CoA <=> 4-hydroxycoumarin + CO2 + 2 CoA


name: 6-linalyl-2-O,3-dimethylflaviolin + diphosphate => (2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin


name: hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate => phosphate + S-methyl-5'-thioinosine


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Bos taurus)


name: B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Sus scrofa)


name: 3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Caenorhabditis elegans)


name: C-terminal Hh fragments are bound by lectins (Sus scrofa)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Schizosaccharomyces pombe)


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Mus musculus)


name: 1-hydroxylimonen-2-one + H(+) + NADPH + O2 = 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: (+)-vincadifformine + acetate + NADP(+) => dihydroprecondylocarpine acetate + NADPH


name: Autocatalytic phosphorylation of FGFR4 (Homo sapiens)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Drosophila melanogaster)


name: L-erythro-N-acylsphing-4-enine + UDP-alpha-D-glucose <=> beta-D-glucosyl-L-erythro-N-acylsphing-4-enine + H(+) + UDP


name: LPA-binding receptors bind LPA (Bos taurus)


name: IL4I1:FAD oxidises L-Phe to kPPV (Mus musculus)


name: HMGCR dimer reduces bHMG-CoA to MVA (Sus scrofa)


name: Arachidonic acid is oxidised to PGG2 by PTGS1 (Canis familiaris)


name: a D-alpha-amino acid + a quinone + H2O => a 2-oxocarboxylate + a quinol + NH4(+)


name: ABC7, mABC1 and mABC2 mediate heme transport (Sus scrofa)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Danio rerio)


name: angiotensin II + L-histidyl-L-leucine => angiotensin I + H2O


name: a 1,2-diacyl-sn-glycerol + lipid A 1-(2-aminoethyl diphosphate) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A


name: EGFR activates PLC-gamma1 by phosphorylation (Canis familiaris)


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Caenorhabditis elegans)


name: biphenyl-2,2',3-triol + H(+) + NADH + O2 = biphenyl-2,2',3,3'-tetraol + H2O + NAD(+)


name: D-sorbitol + O2 => D-sorbopyranose + H2O2


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Sus scrofa)


name: TRAIL-mediated dimerization of procaspase-8 (Mus musculus)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Rattus norvegicus)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Sus scrofa)


name: SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol (Rattus norvegicus)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Canis familiaris)


name: (R)-glycerate + GDP-alpha-D-mannose => (2R)-2-O-(alpha-D-mannosyl)-glycerate + GDP + H(+)


name: PLK1 phosphorylates GORASP1 (Mus musculus)


name: 4-aminobenzoate + H(+) + pyruvate => 4-amino-4-deoxychorismate


name: Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Homo sapiens)


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 = CO2 + cylindrospermopsin + succinate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-hexadecanoylsphinganine => a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-sphinganine-1-phosphocholine


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Bos taurus)


name: Nectin-2:Nectin 3 trans heterodimer interaction (Rattus norvegicus)


name: 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Bos taurus)


name: KIT mutants bind GRB2-SOS (Homo sapiens)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Gallus gallus)


name: ALDH7A1 oxidises BETALD to BET (Sus scrofa)


name: (9Z,12Z)-octadecadienoate + glycerol + H(+) => 2-(9Z,12Z-octadecadienoyl)-glycerol + H2O


name: 4-hydroxyphenylacetate + H(+) + NADH + O2 = H2O + homogentisate + NAD(+)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Canis familiaris)


name: SPHK2 phosphorylates sphingoid (Homo sapiens)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Caenorhabditis elegans)


name: H(+) + hydrogencarbonate + NADH + propanoyl-CoA => 2-methyl-3-oxopropanoate + CoA + H2O + NAD(+)


name: PDGF dimer binds two receptors simultaneously (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] = 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)


name: H2O + N(1)-(3-aminopropyl)agmatine => spermidine + urea


name: [thyroglobulin]-3-iodo-L-tyrosine + H(+) + H2O2 + iodide = [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O


name: AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Rattus norvegicus)


name: Casein kinase II phosphorylates PTEN (Dictyostelium discoideum)


name: all-trans-4-hydroxy-13,14-dihydroretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-13,14-dihydroretinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoserine + ethanolamine


name: CoA + tetradecanyl hexadecanoate => hexadecanoyl-CoA + tetradecan-1-ol


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Mus musculus)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Schizosaccharomyces pombe)


name: (2E,6E)-farnesyl diphosphate + 3,5-dimethylorsellinate = (3R)-3-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylate + diphosphate + H(+)


name: 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate => 10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate


name: 3-sulfanylpentan-1-ol-L-cysteine = 2-aminoprop-2-enoate + 3-sulfanyl-1-pentanol


name: FN3K phosphorylates ketosamines (Rattus norvegicus)


name: SLCO3A1 isoform 1 has abroad substrate specificity (Mus musculus)


name: p38MAPK phosphorylates MSK1 (Sus scrofa)


name: Trafficking of GluR1-containing  AMPA receptors (Mus musculus)


name: CYCS:APAF1 binds procaspase-9 (Danio rerio)


name: Cleavage of uracil by UNG glycosylase (Canis familiaris)


name: Dimerized phospho-IRF3 migrates to the nucleus (Rattus norvegicus)


name: group III metabotropic glutamate receptor activity


name: Complement factor I binds to MCP, CR1:C4b, C3b (Homo sapiens)


name: RCC1 stimulates GDP to GTP exchange on RAN (Plasmodium falciparum)


name: Activated FGFR3 binds FRS2 (Drosophila melanogaster)


name: 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol => a 1-acyl-sn-glycero-3-phosphoethanolamine + a triacyl-sn-glycerol


name: Formation of the CE:GMP intermediate complex (Rattus norvegicus)


name: IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Mus musculus)


name: acetyl-CoA + hexanoyl-CoA = 3-oxooctanoyl-CoA + CoA


name: H2O + hexanedioyl-CoA <=> CoA + H(+) + hexanedioate


name: (3R)-3-hydroxydecanoyl-CoA <=> (2E)-decenoyl-CoA + H2O


name: 3-epihydroxymugineate + CO2 + H(+) + succinate => 2-oxoglutarate + mugineate + O2


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Sus scrofa)


name: Phosphorylated AMPK binds AMP (Sus scrofa)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Caenorhabditis elegans)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Mus musculus)


name: p300 acetylates RELA subunit (Bos taurus)


name: Collagen type V degradation by MMP2,9,10 (Homo sapiens)


name: PRKACA phosphorylates TNNI3 (Canis familiaris)


name: RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)


name: 2 Na(+)(in) + taurodeoxycholate(in) => 2 Na(+)(out) + taurodeoxycholate(out)


name: inorganic cation transmembrane transporter activity


name: Dopa is decarboxylated to dopamine (Rattus norvegicus)


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Homo sapiens)


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Canis familiaris)


name: AMP + H(+) + octanoyl-[ACP] => holo-[ACP] + octanoyl-AMP


name: Interaction of Plectin with Integrin beta 4 (Rattus norvegicus)


name: (2Z,6E)-farnesyl diphosphate => (-)-beta-curcumene + diphosphate


name: Aggrecan binds Hyaluronan and HAPLN1 (Canis familiaris)


name: 3-oxoeicosasphinganine + CO2 + CoA => H(+) + L-serine + octadecanoyl-CoA


name: melibiose:monoatomic cation symporter activity


name: E-cadherin degradation by ADAM10, ADAM15 (Mus musculus)


name: an (S)-2-haloacid + H2O = a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: a fatty acid + S-adenosyl-L-methionine <=> a fatty acid methyl ester + S-adenosyl-L-homocysteine


name: PKCdelta phosphorylates HuR (Homo sapiens)


name: NCOA3 binds ESR1:estrogen:TFGA gene (Rattus norvegicus)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Drosophila melanogaster)


name: Fibronectin degradation by CTSG (Canis familiaris)


name: 2-hydroxytetracosenoyl-CoA + sphinganine = CoA + H(+) + N-(2-hydroxytetracosenoyl)-sphinganine


name: Ligand-independent dimerization of ALK fusions (Homo sapiens)


name: Caspase 3-mediated cleavage of DFF45 (117) (Rattus norvegicus)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Caenorhabditis elegans)


name: Guanine + H2O => Xanthine + NH4+ (Drosophila melanogaster)


name: Caspase-mediated cleavage of Desmoglein 3 (Bos taurus)


name: Transcription of respiratory syncytial virus subgenomic positive sense mRNAs (Homo sapiens)


name: beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + H(+) + UDP => alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP-alpha-D-galactofuranose


name: an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-R + H(+) + UDP


name: "GlcNAc-beta-1,3-Gal beta-1,6-N-acetylglucosaminyltransferase (distally acting)"


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Schizosaccharomyces pombe)


name: ATP + CoA + octadecanoate = AMP + diphosphate + octadecanoyl-CoA


name: Formation of hair keratin fibres (Homo sapiens)


name: an N-(fatty acyl)-L-lysine + H2O = a fatty acid + L-lysine


name: dehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in) => dehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out)


name: Ubiquitinated Orc1 enters the cytosol (Dictyostelium discoideum)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate = african-1-ene + diphosphate


name: chlorophyll a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 7(1)-hydroxychlorophyll a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Canis familiaris)


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Bos taurus)


name: CARNMT1 methylates CARN to Anserine (Schizosaccharomyces pombe)


name: (2R)-3-phosphoglycerate + GDP-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)


name: Class IV antihypertensives bind LTCC multimer (Bos taurus)


name: SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Drosophila melanogaster)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Mus musculus)


name: D-alanine(out) + H(+)(out) => D-alanine(in) + H(+)(in)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Rattus norvegicus)


name: Lactoperoxidase (LPO) produces OSCN- (Mus musculus)


name: 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Drosophila melanogaster)


name: ATP + holo-[CmaA peptidyl-carrier protein] + L-alloisoleucine => AMP + diphosphate + L-alloisoleucyl-[CmaA peptidyl-carrier protein]


name: ANO1 inhibitors bind ANO1 (Canis familiaris)


name: UDP-N-acetylglucosamine transmembrane transporter activity


name: Phosphorylation of SLP-76 by p-SYK (Mus musculus)


name: H(+) + hispidin + NADH + O2 = 3-hydroxyhispidin + H2O + NAD(+)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Plasmodium falciparum)


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: a 3-acyl-sn-glycerol + H2O => a fatty acid + glycerol + H(+)


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Rattus norvegicus)


name: glycerol + NAD(+) => D-glyceraldehyde + H(+) + NADH


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Schizosaccharomyces pombe)


name: HSD11B2 dehydrogenates PREDL to PREDN (Drosophila melanogaster)


name: 3-phenylpropanoate + NAD(+) <=> (E)-cinnamate + H(+) + NADH


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR (Rattus norvegicus)


name: SARS-CoV-2 M protein binds MAP1LC3B (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate


name: ME1 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)


name: 1-heptadecanoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA => 1-heptadecanoyl-sn-glycero-3-phosphate + dodecanoyl-CoA


name: H2O + taurochenodeoxycholate => chenodeoxycholate + taurine


name: RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)


name: H2O + succinyl-CoA <=> CoA + H(+) + succinate


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: L-aspartate(out) + L-phenylalanine(in) => L-aspartate(in) + L-phenylalanine(out)


name: H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1248) in human 18S rRNA + S-methyl-5'-thioadenosine => N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine


name: PTK2 autophosphorylates (Xenopus tropicalis)


name: ascochlorin + 2 H2O + NADP(+) => H(+) + ilicicolin C + NADPH + O2


name: SALL4 binds the PTEN gene promoter (Homo sapiens)


name: L-leucine + neurotensin-(1-12) => H2O + neurotensin


name: erythromycin D + H(+) + NADPH + O2 => erythromycin C + H2O + NADP(+)


name: L-tryptophan + O2 => N-formyl-L-kynurenine


name: beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Dictyostelium discoideum)


name: RAC3 translocates to the endoplasmic reticulum membrane (Bos taurus)


name: [(1->4)-alpha-D-galacturonosyl](n) + H2O = [(1->4)-alpha-D-galacturonosyl](n-2) + alpha-D-galacturonosyl-(1->4)-D-galacturonate


name: H2O + N-hexadecanoylethanolamine <=> ethanolamine + hexadecanoate


name: Spherical HDL binds C and E apolipoproteins (Bos taurus)


name: PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane (Homo sapiens)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Canis familiaris)


name: ROCK activation by RHO (Canis familiaris)


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Xenopus tropicalis)


name: stretch-activated, monoatomic cation-selective, calcium channel activity


name: HOXD1 chromatin is activated (Homo sapiens)


name: guanosine(2270) in 21S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2270) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Bos taurus)


name: DEK binds TFAP2A homodimers (Canis familiaris)


name: Ca2+ influx through voltage gated Ca2+ channels (Drosophila melanogaster)


name: (2E,9Z)-hexadecadienoyl-[ACP] + H2O => (3R)-hydroxy-(9Z)-hexadecenoyl-[ACP]


name: KCNJs transport K+ from the extracellular region to cytosol (Drosophila melanogaster)


name: 19-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase]


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: ACLY tetramer transforms CIT to Ac-CoA (Sus scrofa)


name: HSF1 trimer translocates to the nucleus (Sus scrofa)


name: [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-beta-macrocarpene + O2 + reduced [NADPH--hemoprotein reductase]


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol => a 1,3-diacyl-sn-glycerol + a monoacyl-sn-glycero-3-phosphocholine


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Saccharomyces cerevisiae)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 4-[(E)-2-isocyanoethenyl]phenol + 2 CO2 + H2O + succinate


name: USP8 deubiquitinates LRIG1 (Gallus gallus)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Dictyostelium discoideum)


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Gallus gallus)


name: Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Homo sapiens)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Homo sapiens)


name: CO2 + deoxyviolacein + 2 H2O + NAD(+) => 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate


name: p-EFNB binds GRB4 (Caenorhabditis elegans)


name: WLS is endocytosed to the early endosome (Sus scrofa)


name: Trimming of peptides in ER (Dictyostelium discoideum)


name: an N-acyl-(2S)-hydroxyglycine + H2O + 2 monodehydro-L-ascorbate radical => an N-acylglycine + 2 L-ascorbate + O2


name: D-tagatofuranose 1,6-bisphosphate => D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate


name: (+)-valencene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-nootkatol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-acyl LPS is acylated to PS by LPSAT (Caenorhabditis elegans)


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Bos taurus)


name: H(+) + lactose + UDP => D-glucose + UDP-alpha-D-galactose


name: ULK1 phosphorylates ATG13 and RB1CC1 (Gallus gallus)


name: alpha-ribazole 5'-phosphate + H2O => alpha-ribazole + phosphate


name: Minus strand DNA synthesis resumes (Homo sapiens)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Rattus norvegicus)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Canis familiaris)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Rattus norvegicus)


name: (2R,3S)-tartrate + NAD(+) => 2-hydroxy-3-oxosuccinate + H(+) + NADH


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)


name: 4-guanidinobutanoate + NH4(+) => 4-guanidinobutanamide + H2O


name: (E)-3-(indol-3-yl)acryloyl-CoA + (R)-3-(indol-3-yl)lactate = (E)-3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA


name: (2S)-ethylmalonyl-CoA + NADP(+) => (2E)-butenoyl-CoA + CO2 + NADPH


name: TP73 tetramer translocates to the nucleus (Rattus norvegicus)


name: ATP + L-seryl-[myosin light chain] = ADP + H(+) + O-phospho-L-seryl-[myosin light chain]


name: H2O + phosphoenolpyruvate <=> phosphate + pyruvate


name: HGFAC cleaves pro-HGF to form HGF dimer (Mus musculus)


name: [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) = [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: ABCB1 transports xenobiotics out of the cell (Sus scrofa)


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Canis familiaris)


name: (-)-(E)-beta-caryophyllene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 2 5,6-dihydroxyindole-2-carboxylate + O2 <=> 2 H2O + 2 indole-5,6-quinone-2-carboxylate


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Bos taurus)


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Plasmodium falciparum)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Mus musculus)


name: myo-inositol + phosphate => a myo-inositol phosphate + H2O


name: heptan-1-ol + NADP(+) => H(+) + heptanal + NADPH


name: ARTN binds RET:GFRA1,GFRA3 (Gallus gallus)


name: KCTD1 binds TFAP2 homo- and heterodimers (Mus musculus)


name: a long-chain fatty acid + 3 H(+) + 2 NADH => a long-chain primary fatty alcohol + H2O + 2 NAD(+)


name: CDC6 association with ORC(1-6) at replication origins (Homo sapiens)


name: 5-(3-methylguanidino)-2-oxopentanoate + glycine => glyoxylate + N(omega)-methyl-L-arginine


name: (2S)-2-nitrosobutanedioate + H2O => N,N-dihydroxy-L-aspartate


name: RHOH binds effectors at the plasma membrane (Bos taurus)


name: PKC autophosphorylates (Saccharomyces cerevisiae)


name: 13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+) => 15-oxoprostaglandin F1alpha + H(+) + NADPH


name: (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: CYP21A2 oxidises 17HPROG (Canis familiaris)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Gallus gallus)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Drosophila melanogaster)


name: Polyubiquitinated RUNX3 translocates to the cytosol (Sus scrofa)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O


name: 3-phenyllactate + NADP(+) = 3-phenylpyruvate + H(+) + NADPH


name: HDACs deacetylate p-STAT3 dimers (Dictyostelium discoideum)


name: CD59 inhibits MAC formation (Homo sapiens)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O => (9Z)-octadecenoate + 1,3-dihexadecanoylglycerol + H(+)


name: CTP + H(+) + N(5)-phospho-L-glutamine = diphosphate + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Gallus gallus)


name: LTA trimer binds TNFRSF1A,1B,14 (Xenopus tropicalis)


name: acetyl-CoA + an acyl-CoA = a 3-oxoacyl-CoA + CoA


name: (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+) = biphenyl-2,3-diol + H(+) + NADH


name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Drosophila melanogaster)


name: heptan-2-one + hydrogen cyanide => (2S)-2-hydroxy-2-methylheptanenitrile


name: GPR35 binds kynurenic acid (Homo sapiens)


name: 2 3-(4-hydroxyphenyl)pyruvate + O2 <=> 2 4-hydroxyphenylacetate + 2 CO2


name: DAG activation of TRPC channels (Mus musculus)


name: FOXG1 binds FOXO:SMAD complexes (Canis familiaris)


name: D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate


name: formononetin + UDP-alpha-D-glucose <=> ononin + UDP


name: LDH tetramer oxidises LACT to PYR (Canis familiaris)


name: chenodeoxycholate + NADP(+) = 3-oxochenodeoxycholate + H(+) + NADPH


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Homo sapiens)


name: AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)


name: 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + H2O => 2-O-(alpha-D-glucopyranosyl)glycerol + phosphate


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Sus scrofa)


name: T1R2/T1R3 dimer is a sweet taste receptor (Mus musculus)


name: SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Sus scrofa)


name: DLD dimer dehydrogenates dihydrolipoyl (Mus musculus)


name: HYKK phosphorylates 5HLYS (Canis familiaris)


name: 1,3,7-trimethylurate + H(+) + NADH + O2 = 1,3,7-trimethyl-5-hydroxyisourate + H2O + NAD(+)


name: a 3-oxo acid + succinyl-CoA => a 3-oxoacyl-CoA + succinate


name: (+)-copalyl diphosphate => diphosphate + miltiradiene


name: (2E,6E)-farnesyl diphosphate = calarene + diphosphate


name: PLK1 phosphorylates FIRRM at S43 (Rattus norvegicus)


name: 2 H(+) + malonate + NADH => 3-oxopropanoate + H2O + NAD(+)


name: Disassociation of Processive Complex and Completed Telomere End (Rattus norvegicus)


name: ALOX15 oxidises 17(S)-Hp-DHA to PDX (Sus scrofa)


name: BRD7 binds TP53 and EP300 (Mus musculus)


name: Parathyroid hormone receptor can bind parathyroid hormone (Bos taurus)


name: PIAS1,3 SUMOylate ESR1 with SUMO1 (Homo sapiens)


name: A + rhodopin => (3E)-3,4-didehydrorhodopin + AH2


name: H2O + N-acetyl-L-lysine = acetate + L-lysine


name: (2E,15Z)-tetracosadienoyl-CoA + H2O => (3R)-hydroxy-(15Z)-tetracosenoyl-CoA


name: (6R)-5,10-methenyltetrahydrofolate + H2O + N(1)-(5-phospho-beta-D-ribosyl)glycinamide <=> (6S)-5,6,7,8-tetrahydrofolate + 2 H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide


name: a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate => a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O


name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Mus musculus)


name: RNA exonuclease activity, producing 5'-phosphomonoesters


name: VRK1/VRK2 phosphorylate BANF1 (Canis familiaris)


name: Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Bos taurus)


name: HERC2 and PIAS4 are recruited to DNA DSBs (Rattus norvegicus)


name: CoA + H(+) + N(2)-succinyl-L-arginine => L-arginine + succinyl-CoA


name: RSV F binds TLR4:LY96:CD14 (Homo sapiens)


name: 15,9'-di-cis-phytofluene + a plastoquinol => 15-cis-phytoene + a plastoquinone


name: a cholesterol ester(in) => a cholesterol ester(out)


name: (E)-caffeate + ATP + H(+) + 2 malonyl-CoA = AMP + 2 CO2 + 2 CoA + diphosphate + hispidin


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Bos taurus)


name: ITP + N-acetyl-D-glucosamine <=> H(+) + IDP + N-acetyl-D-glucosamine 6-phosphate


name: dihydrochanoclavine-I aldehyde + NADP(+) = chanoclavine-I aldehyde + H(+) + NADPH


name: beta-L-fucose + NADP(+) <=> H(+) + L-fucono-1,5-lactone + NADPH


name: malvidin + UDP-alpha-D-glucose => malvidin 3-O-beta-D-glucoside + UDP


name: SARS-CoV-2 N binds to 14-3-3 proteins (Homo sapiens)


name: CHD1L is recruited to GG-NER site (Bos taurus)


name: Interaction of MyoD:E protein with MEF2 (Rattus norvegicus)


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + 2-oxoglutarate + H(+) + H2O => GDP-4-dehydro-alpha-D-rhamnose + L-glutamate


name: ATM recognizes H2AFX-Nucleosomes (Homo sapiens)


name: a fatty acid + glycerol + H(+) => a 2-acylglycerol + H2O


name: (2E,6E,10E)-geranylgeranyl diphosphate = cembrene C + diphosphate


name: ACBD6 binds LCFA-CoA (Caenorhabditis elegans)


name: DREAM complex binds the TOP2A gene promoter (Homo sapiens)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Bos taurus)


name: LTA4 is converted to EXA4 by ALOX15 (Bos taurus)


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Homo sapiens)


name: A + H2O + isoquinoline <=> AH2 + isoquinolin-1(2H)-one


name: Cipro is imported by organic cation transporters (Homo sapiens)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Bos taurus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Danio rerio)


name: eicosanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-nonadecylpyran-2-one + 2 CO2 + 3 CoA


name: (R)-lipoate(out) + 2 Na(+)(out) <=> (R)-lipoate(in) + 2 Na(+)(in)


name: 6alpha-hydroxycastasterone + O2 + reduced [NADPH--hemoprotein reductase] = castasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + (S)-mandelate + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + (S)-4-hydroxymandelate + H2O


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol => all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol


name: G-beta:G-gamma inhibits Adenylate cyclase (Danio rerio)


name: HRH2 binds HRH2 antagonists (Drosophila melanogaster)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Homo sapiens)


name: 3-oxotetracosanoyl-CoA + H(+) + NADPH => (3R)-hydroxytetracosanoyl-CoA + NADP(+)


name: 7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) <=> 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: H2O + NAD(+) + NH4(+) => 2 H(+) + hydroxylamine + NADH


name: VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Homo sapiens)


name: (+)-epi-isozizaene + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => albaflavenone + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: diphosphate + N-geranyl-L-glutamate => (2E)-geranyl diphosphate + L-glutamate


name: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) => a very-long-chain 3-oxoacyl-CoA + H(+) + NADPH


name: 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: ROCK activation by RHO (Caenorhabditis elegans)


name: 1-hydroxy-6-methoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-methionine <=> 1,6-dimethoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-homocysteine


name: 1-docosanoylglycerol + H2O => docosanoate + glycerol + H(+)


name: ATP + beta-alanine + histamine = AMP + carcinine + diphosphate + H(+)


name: Aquaporins passively transport glycerol into cells (Caenorhabditis elegans)


name: 2-oxobutanoate + L-glutamine <=> (2S)-2-aminobutanoate + 2-oxoglutaramate


name: (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + AH2 => (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + A


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Mus musculus)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + ATP <=> 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: RHOD binds effectors at the Golgi membrane (Xenopus tropicalis)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Rattus norvegicus)


name: 1-O-hexadecyl-sn-glycero-3-phosphate + ADP + H(+) => 1-O-hexadecyl-sn-glycerol + ATP


name: p-S54,92,203-BRF1 binds 14-3-3 (Homo sapiens)


name: 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O => (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: L-seryl-[protein] + UDP-alpha-D-xylose => 3-O-(beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP


name: 12 H(+) + 6 malonyl-CoA + NADH + 5 NADPH = (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + 6 CO2 + 6 CoA + 4 H2O + NAD(+) + 5 NADP(+)


name: H2O + N(omega)-(ADP-D-ribosyl)-L-arginine <=> ADP-D-ribose + L-arginine


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Bos taurus)


name: ABCE1 binds RNASEL, inhibiting it (Sus scrofa)


name: Pink1 is cleaved on healthy mitochondria (Canis familiaris)


name: 6-O-alpha-D-glucopyranosyl-D-fructose + H2O = alpha-D-glucose + D-fructose


name: Carbonic anhydrase dehydrates bicarbonate (plasma membrane) (Canis familiaris)


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Homo sapiens)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Bos taurus)


name: 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = H(+) + lipid A disaccharide (E. coli) + UDP


name: ARV1 transports CHOL from ER membrane to plasma membrane (Rattus norvegicus)


name: Calcium Influx through Voltage-gated Calcium Channels (Rattus norvegicus)


name: RNA polymerase II core promoter sequence-specific DNA binding


name: ZFP36 (TTP) recruits RNA degradation activities (Homo sapiens)


name: 9alpha-copalyl diphosphate => (12E)-9alpha-labda-8(17),12,14-triene + diphosphate


name: a 2-acylphloroglucinol 1-O-beta-D-glucoside + UDP => a 2-acylphloroglucinol + UDP-alpha-D-glucose


name: SLC25A10 mediates exchange of malate and phosphate (Caenorhabditis elegans)


name: PTK6 phosphorylates KHDRBS2 (Xenopus tropicalis)


name: ADH5 oxidises S-HMGSH to S-FGSH (Dictyostelium discoideum)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)


name: KAT5 HAT complex acetylates TCF4 gene at histone H4 (Homo sapiens)


name: acetyl-CoA + D-aspartate => CoA + H(+) + N-acetyl-D-aspartate


name: L-alanine + L-glutamine => H2O + L-alanyl-L-glutamine


name: CALCR binds erenumab (Drosophila melanogaster)


name: Palmostatin B binds RAS depalmitoylases (Caenorhabditis elegans)


name: GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Drosophila melanogaster)


name: Cannabinoid receptors can bind cannabinoids (Canis familiaris)


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Canis familiaris)


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Bos taurus)


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Xenopus tropicalis)


name: SUMOylation of Histone H4 with SUMO1 (Dictyostelium discoideum)


name: SARS-CoV-2 nsp9 binds to 7SL RNA (Homo sapiens)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Caenorhabditis elegans)


name: H2O + L-alanine + O2 => H2O2 + NH4(+) + pyruvate


name: PIP2 hydrolysis (Dictyostelium discoideum)


name: A + H2O + uracil <=> AH2 + barbiturate + H(+)


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Canis familiaris)


name: (+)-larreatricin + AH2 + O2 = (+)-3'-hydroxylarreatricin + A + H2O


name: [glutaredoxin]-dithiol + arsenate + glutathione + H(+) <=> arsenite + glutathionyl-S-S-[glutaredoxin] + H2O


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Canis familiaris)


name: GLUT1 tetramer binds 4xATP (Gallus gallus)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 <=> (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine


name: IKKbeta phosphorylates IkB causing NF-kB to dissociate (Gallus gallus)


name: PDE4A binds PDE4A inhibitors (Canis familiaris)


name: (2S)-3-sulfolactaldehyde + H(+) + NADH => (2S)-3-sulfopropanediol + NAD(+)


name: ATP + beta-D-fructose 6-phosphate => ADP + beta-D-fructose 2,6-bisphosphate + H(+)


name: 3-hydroxy-4-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) => 3,4-dihydroxybenzoate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: Polyubiquitination of substrate (Bos taurus)


name: (+)-kolavelool + S-adenosyl-L-methionine = (+)-O-methylkolavelool + H(+) + S-adenosyl-L-homocysteine


name: CoA + H(+) + N-tetradecanoyl-3-oxosphinganine => 3-oxosphinganine + tetradecanoyl-CoA


name: a quinone + glutathione + H(+) + hydrogen sulfide => a quinol + S-sulfanylglutathione


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-epicubenol + diphosphate


name: Separation of elongating transcript from template (Canis familiaris)


name: 2-oxoglutarate + L-asparagine <=> 2-oxosuccinamate + L-glutamate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA => 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Plasmodium falciparum)


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Mus musculus)


name: 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine <=> 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: RHOQ binds effectors at the plasma membrane (Dictyostelium discoideum)


name: Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA (Sus scrofa)


name: H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone => N,N',N''-triacetylchitotriose + O2


name: eburicol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 14-demethyleburicol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: CDC42 GEFs activate CDC42 (Gallus gallus)


name: p-PKR dimer phosphorylates DHX9 (Bos taurus)


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Gallus gallus)


name: Activated PCLG1 dissociates from NTRK2 (Bos taurus)


name: 3-sulfino-L-alanine + H(+) <=> CO2 + hypotaurine


name: dGMP(out) + NAD(+)(in) => dGMP(in) + NAD(+)(out)


name: AKAP5 recruits PKC to ROBO2 (Homo sapiens)


name: beta-D-glucose 1-phosphate + D-glucose => kojibiose + phosphate


name: CYP2C19 5-hydroxylates omeprazole (Dictyostelium discoideum)


name: gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity


name: cholesteryl 3-beta-D-glucoside + H2O <=> cholesterol + D-glucose


name: (R)-dihydrocamalexate + O2 + reduced [NADPH--hemoprotein reductase] = camalexin + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E)-geranyl diphosphate => (1S,5S)-beta-pinene + diphosphate


name: 2-hydroxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP => 2-hydroxyestrone + UDP-alpha-D-glucuronate


name: copper chelate transmembrane transporter activity


name: H(+) + hexan-3-one + NADPH + O2 = H2O + NADP(+) + propyl propanoate


name: RPE65 isomero-hydrolyses atREs to 11cROL (Mus musculus)


name: ACER2 hydrolyzes ceramide (Golgi) (Drosophila melanogaster)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Schizosaccharomyces pombe)


name: Conversion of glyoxylate to oxalate (Drosophila melanogaster)


name: androst-4-ene-3,17-dione + H(+) + NADH => NAD(+) + testosterone


name: STAB1 (FEEL-1) binds ligands (Danio rerio)


name: (1S,4S)-camphor + H(+) + NADH => (+)-isoborneol + NAD(+)


name: Syndecan-1 binds fibronectin (Mus musculus)


name: Formation of the pre-incision complex in GG-NER (Canis familiaris)


name: a 2'-deoxycytidine in double-stranded DNA + CO2 + glyoxal + succinate => 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + H2O + O2


name: ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Canis familiaris)


name: an (R)-2-haloacid + H2O = a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: SAMD8 transfers phosphatidyl from PE onto C16DH CER (Caenorhabditis elegans)


name: a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + H(+) + NADPH + O2 => a (Z)-omega-(methylsulfinyl)-alkyl-glucosinolate + H2O + NADP(+)


name: RAC3 translocates to the endoplasmic reticulum membrane (Sus scrofa)


name: NLK translocates to nucleus (Gallus gallus)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Canis familiaris)


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Xenopus tropicalis)


name: ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] (Gallus gallus)


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Gallus gallus)


name: Formation of Malonyl-CoA from Acetyl-CoA (liver) (Dictyostelium discoideum)