name: a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1b + CMP + H(+)


name: (3S)-3,6-diaminohexanoate + acetyl-CoA => (3S)-6-acetamido-3-aminohexanoate + CoA + H(+)


name: 3-dehydro-4-O-phospho-L-erythronate + H(+) <=> CO2 + dihydroxyacetone phosphate


name: GDIs bind RHOH (Dictyostelium discoideum)


name: H(+) + hexanoyl-CoA + oxidized [electron-transfer flavoprotein] <=> (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]


name: H(+) + o-quinone methide + penilactone D <=> penilactone B


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Dictyostelium discoideum)


name: VEGFR2 autophosphorylates (Canis familiaris)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + ouabagenin = dihydroouabagenin + 2 Fe(III)-[cytochrome c]


name: PDE4A hydrolyses cAMP to AMP (Bos taurus)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Drosophila melanogaster)


name: AOX1 oxidises PXL to PDXate (Xenopus tropicalis)


name: ent-cassa-12,15-dien-2beta,3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: histidine => urocanate + NH4+ (Rattus norvegicus)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O <=> (9Z,12Z)-octadecadienoate + di-(9Z,12Z)-octadecadienoylglycerol + H(+)


name: H2O + lactobiono-1,5-lactone => H(+) + lactobionate


name: 2-oxoglutarate + O2 + pentalenolactone D => CO2 + H2O + pentalenolactone E + succinate


name: MCM3 binds MCM5 (Dictyostelium discoideum)


name: 2-oxoglutarate + O2 + thymine <=> 5-hydroxymethyluracil + CO2 + succinate


name: guanosine(in) + H(+)(out) = guanosine(out) + H(+)(in)


name: MTORC1 dissociates from ULK complex (Caenorhabditis elegans)


name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Mus musculus)


name: catechol + S-adenosyl-L-methionine => guaiacol + H(+) + S-adenosyl-L-homocysteine


name: ADH5 oxidises S-HMGSH to S-FGSH (Xenopus tropicalis)


name: ADP + H(+) + pyridoxal 5'-phosphate => ATP + pyridoxal


name: dimethyl sulfide + 2 Fe(III)-[cytochrome c2] + H2O => dimethyl sulfoxide + 2 Fe(II)-[cytochrome c2] + 2 H(+)


name: GAB1 phosphorylation by EGFR kinase (Sus scrofa)


name: Collagen type XIII binds Integrin alpha1beta1 (Sus scrofa)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-phenylalanyl-[tubulin] + H2O => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-phenylalanine


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) = a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Canis familiaris)


name: BIL dissociates from GSTA1, FABP1 (Danio rerio)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)


name: RISC binds inexactly matching target RNAs (Rattus norvegicus)


name: NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)


name: Casein kinase II phosphorylates PTEN (Schizosaccharomyces pombe)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Mus musculus)


name: RAC2 translocates to the phagocytic vesicle membrane (Gallus gallus)


name: an N-acetyl-L-cysteine-S-conjugate + CoA + H(+) => acetyl-CoA + an S-substituted L-cysteine


name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Bos taurus)


name: (2R)-octan-2-ol + NADP(+) => 2-octanone + H(+) + NADPH


name: MITF-M dimer binds GMPR gene (Homo sapiens)


name: (2R)-3-phosphoglycerate + GTP + H(+) = 3-[(R)-glyceryl]-diphospho-5'-guanosine + diphosphate


name: The receptor:G-protein complex releases GDP (Caenorhabditis elegans)


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Rattus norvegicus)


name: a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine


name: Phosphorylation of Syntaxin-4 (Saccharomyces cerevisiae)


name: 7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O => 7,8-dihydroneopterin 3'-phosphate + H(+)


name: 2-hydroxy-2-methylpropanal + H(+) + NADH => 2-methylpropane-1,2-diol + NAD(+)


name: H2O + 3 O2 + 3 propionate 3-nitronate = 3 3-oxopropanoate + 3 H(+) + H2O2 + 2 nitrate + nitrite


name: ALAD condenses 2 dALAs to form PBG (Schizosaccharomyces pombe)


name: PKM dephosphorylates PEP to PYR (Danio rerio)


name: peptidase activator activity involved in apoptotic process


name: EP300,CREBBP bind SOH-C481-FOXO4 (Homo sapiens)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Dictyostelium discoideum)


name: (S)-malate + NADP(+) = CO2 + NADPH + pyruvate


name: UROS transforms HMB to URO3 (Drosophila melanogaster)


name: phosphoenolpyruvate carboxykinase (GTP) activity


name: L-glutamate(in) + 2 Na(+)(in) => L-glutamate(out) + 2 Na(+)(out)


name: ADP + dimethylallyl diphosphate => diphosphate + N(6)-(dimethylallyl)adenosine 5'-diphosphate


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Caenorhabditis elegans)


name: 3,5-dichlorocatechol + O2 => (2E,4E)-2,4-dichloromuconate + 2 H(+)


name: H2O + N-octadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-octadecanoyl ethanolamine


name: H(+)(in) + L-alanine(in) <=> H(+)(out) + L-alanine(out)


name: TP53RK phosphorylates TP53 (Canis familiaris)


name: 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + macrocyclic archaeol => AH2 + archaeol + 2 S-adenosyl-L-methionine


name: a globoside Gb4Cer + H(+) + UDP => a globoside Gb3Cer + UDP-N-acetyl-alpha-D-galactosamine


name: TPMT transfers methyl group to 6TIMP, forming 6MeTIMP (Canis familiaris)


name: Loss of SAR1B GTPase (Saccharomyces cerevisiae)


name: MCPH1 sequesters condensin II (Bos taurus)


name: Thr-180 of ULK1 is phosphorylated (Mus musculus)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: citrate(out) + maleate(in) = citrate(in) + maleate(out)


name: D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H(+) + H2O2


name: phomoidride A + S-adenosyl-L-methionine <=> (-)-phomoidride B + H(+) + methanol + S-adenosyl-L-homocysteine


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Caenorhabditis elegans)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 = 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O


name: (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S,14S)-dihydroperoxy-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoate


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2 => (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanedioate + H(+) + H2O2


name: D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose


name: ALOX5 binds ALOX5 inhibitors (Rattus norvegicus)


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Dictyostelium discoideum)


name: JAK1 binds IL4R in IL13-bound IL13R type II (Homo sapiens)


name: Dephosphorylation of STAT1 by SHP2 (Gallus gallus)


name: ERCC5 and RPA bind TC-NER site (Sus scrofa)


name: 3-oxodocosanoyl-CoA + H(+) + NADPH => (3R)-hydroxydocosanoyl-CoA + NADP(+)


name: IL35 binds IL12RB2:IL12RB2 receptor (Rattus norvegicus)


name: adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine => H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine


name: 1-beta-D-galactosyl-dodecanoyl-sn-glycerol + dodecanoate + H(+) => 1-beta-D-galactosyl-2,3-didodecanoyl-sn-glycerol + H2O


name: SFTPD binds with itself to form SFTPD 12mer (Bos taurus)


name: Release of novel PDGFs as latent factors (Sus scrofa)


name: ABHD4 hydrolyses NAPE (Drosophila melanogaster)


name: holo-[citrate lyase ACP] + S-acetylphosphopantotheine = (R)-4'-phosphopantetheine + acetyl-[citrate lyase ACP]


name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-(2S,3R,9R)-pristinol + diphosphate


name: NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)


name: NOX2 generates superoxide anion from oxygen (Xenopus tropicalis)


name: gp130:JAKs bind CNTFR (Rattus norvegicus)


name: 2-oxoglutarate + hexanoyl-CoA + O2 => 2-hydroxyhexanoyl-CoA + CO2 + succinate


name: Activation of RAS by p-KIT bound SOS1 (Xenopus tropicalis)


name: a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GP1c (d18:1(4E)) + CMP + H(+)


name: 8-oxo-GTP + H2O = 8-oxo-GDP + H(+) + phosphate


name: Lysosomal degradation of gap junction plaques (Canis familiaris)


name: Expression of IRX2 during nephron development (Homo sapiens)


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Bos taurus)


name: CaMKK autophosphorylates in the nucleus (Schizosaccharomyces pombe)


name: H(+) + L-rhamnonate => H2O + L-rhamnono-1,4-lactone


name: benzylthiol + O2 => benzothialdehyde + H2O2


name: (E)-4-hydroxynon-2-en-1-ol + NADP(+) = (E)-4-hydroxynon-2-enal + H(+) + NADPH


name: 7,8-dihydrofolate + ADP + H(+) + phosphate => 7,8-dihydropteroate + ATP + L-glutamate


name: myo-inositol + S-adenosyl-L-methionine = 1D-1-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: CyP60 chaperones Basigin (Rattus norvegicus)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate => adenosine 5'-tetraphosphate + AMP + 2 H(+)


name: SUMOylation of DAXX with SUMO1 (Sus scrofa)


name: ESR1 binds the AXIN1 gene (Homo sapiens)


name: luteolin 4',7-dimethyl ether + S-adenosyl-L-homocysteine => diosmetin + S-adenosyl-L-methionine


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Gallus gallus)


name: H2O + ML-236C carboxylate => 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate


name: 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+) => L-tyrosine + NADPH + S-adenosyl-L-methionine


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)


name: ATP + L-tryptophan => diphosphate + L-tryptophyl-5'-AMP


name: Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Saccharomyces cerevisiae)


name: ATPase-coupled L-glutamine transmembrane transporter activity


name: 1-O-alkyl-sn-glycero-3-phosphate + acetyl-CoA <=> 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA


name: (2R)-3-phosphoglycerate + ADP + H(+) => (R)-glycerate + ATP


name: DAG and Ca+2 bind to PKC and tether it to membrane (Danio rerio)


name: PC is exchanged with PI by PITPNB (Rattus norvegicus)


name: MHC class I protein binding, via lateral surface


name: Loading of antigenic peptides (Canis familiaris)


name: SDK2 homophillic interaction (Caenorhabditis elegans)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Caenorhabditis elegans)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Canis familiaris)


name: 2 L-ascorbate + N-dodecanoylglycine + O2 = H2O + 2 monodehydro-L-ascorbate radical + N-dodecanoyl-(2S)-hydroxyglycine


name: H2O + N-methylhexanamide => hexanoate + methylamine


name: chlorate(out) + 2 Na(+)(out) = chlorate(in) + 2 Na(+)(in)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Dictyostelium discoideum)


name: L-valine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-valine + oxidized [NADPH--hemoprotein reductase]


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Rattus norvegicus)


name: Coumarin is 7-hydroxylated by CYP2A6 (Caenorhabditis elegans)


name: ING2-bound EP300 acetylates TP53 (Xenopus tropicalis)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Sus scrofa)


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)


name: H(+) + NADPH + NH4(+) + pentanal => H2O + NADP(+) + pentylamine


name: Caspase mediated cleavage of HIP-55 (Drosophila melanogaster)


name: WLS dissociates from retromer (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate + H2O = 4-terpineol + diphosphate


name: D-xylulose 5-phosphate + phosphate => acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O


name: carboxylic acid transmembrane transporter activity


name: Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane (Homo sapiens)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine => a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine


name: AP2 binds chlorpromazine (Gallus gallus)


name: Beta-catenin:TCF associates with BCL9 and PYGO (Bos taurus)


name: a ganglioside GQ1b (d18:1(4E)) + H2O = a ganglioside GT1b (d18:1(4E)) + N-acetylneuraminate


name: AGFG1 binds VAMP7 (Drosophila melanogaster)


name: ATP + L-glutamate + putrescine => ADP + gamma-L-glutamylputrescine + H(+) + phosphate


name: B3GNT5 transfers GlcNAc to LacCer (Drosophila melanogaster)


name: USP3,SAGA deubiquitinate Histone H2A,H2B (Xenopus tropicalis)


name: S100A7 or S100A7A binds Zn2+ (Gallus gallus)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Canis familiaris)


name: D-cellopentaono-1,5-lactone + H2O => D-cellopentaonate + H(+)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Saccharomyces cerevisiae)


name: Dynamin is recruited to the gap junction plaque (Mus musculus)


name: p85 regulatory unit of PI3K binds p-6Y-SYK (Mus musculus)


name: TRIM21 ubiquitinates SQSTM1 (Canis familiaris)


name: Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Bos taurus)


name: an alkyl thiol + NH4(+) + pyruvate => an S-alkyl-L-cysteine + H2O


name: Autophosphorylation of PTK2 at Y397 (Canis familiaris)


name: Neuroglobin binds oxygen (Caenorhabditis elegans)


name: α1-agonists bind ADRA1A,B,D (Gallus gallus)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Canis familiaris)


name: methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine


name: GDP-alpha-D-mannose + N,N'-diacetylchitobiosyl diphosphodolichol = beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: miR-106 microRNAs bind PTEN mRNA (Homo sapiens)


name: SEC24A,B:SEC23A bind SEC22B (Saccharomyces cerevisiae)


name: chelirubine + NADH => dihydrochelirubine + NAD(+)


name: dimethylallyl diphosphate + 5 isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + 5 diphosphate


name: RCC1 stimulates GDP to GTP exchange on RAN (Rattus norvegicus)


name: CERT1-2 complex dissociates (Danio rerio)


name: AMP + ATP <=> ADP + ADP [AK2] (Danio rerio)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Canis familiaris)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Homo sapiens)


name: Interaction of GRB2:SOS complex with p-SHC1 (Mus musculus)


name: (4S)-3(1),4-dihydroxy-L-isoleucine + CO2 + succinate => 2-oxoglutarate + 3(1)-hydroxy-L-isoleucine + O2


name: (S)-2-amino-6-oxohexanoate + holo-[LYS2 peptidyl-carrier protein] + NADP(+) => H(+) + L-2-aminoadipyl-[LYS2 peptidyl-carrier protein] + NADPH


name: LIG3 ligates remaining SSBs in MMEJ (Mus musculus)


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Bos taurus)


name: Activation of Rap1 by cytosolic GEFs (Gallus gallus)


name: p-MAPK2/3 phosphorylates HSP27 (Mus musculus)


name: Disassembly of SR-BI-bound spherical HDL (Mus musculus)


name: L-erythrulose 1-phosphate <=> D-erythrulose 4-phosphate


name: (2S)-2-methylbutanoyl-CoA + H(+) + malonyl-[ACP] => (4S)-4-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA


name: ADP + beta-citrylglutamate + H(+) + phosphate => ATP + citrate + L-glutamate


name: Translocation of PLC-gamma1 to PIP2 (Saccharomyces cerevisiae)


name: alpha-D-glucose + ATP <=> ADP + alpha-D-glucose 6-phosphate + H(+)


name: BTNL9 binds immune cell surfaces (Xenopus tropicalis)


name: (2Z,6Z)-farnesyl diphosphate + isopentenyl diphosphate => diphosphate + nerylneryl diphosphate


name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Canis familiaris)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Saccharomyces cerevisiae)


name: (indol-3-yl)acetonitrile + sulfate + sulfur => (Z)-(indol-3-yl)-N-(sulfonatooxy)methanimidothioate


name: 4-hydroxy-3-all-trans-octaprenylbenzoate + H(+) => 2-all-trans-octaprenylphenol + CO2


name: decan-1-ol + NADP(+) => decanal + H(+) + NADPH


name: 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O <=> 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Mus musculus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine <=> 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin


name: RHAG transports CO2 from cytosol to extracellular region (Sus scrofa)


name: ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 (Canis familiaris)


name: 2 H(+) + NADH + octadecanoate => H2O + NAD(+) + octadecanal


name: p-Y705-STAT3 binds p-Y693-STAT4 (Gallus gallus)


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Danio rerio)


name: high-density lipoprotein particle receptor activity


name: (11R)-19-oxocarlactone + O2 + reduced [NADPH--hemoprotein reductase] => (11R)-carlactonoate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone <=> H(+) + N,N',N'',N'''-tetraacetylchitotetraonate


name: 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Danio rerio)


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Caenorhabditis elegans)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Rattus norvegicus)


name: Activated IKBKB phosphorylates IRF5 (Bos taurus)


name: USP16,USP21 deubiquitinate Histone H2A (Homo sapiens)


name: H2O + N(omega)-hydroxy-L-arginine => hydroxyurea + L-ornithine


name: Recruitment of elongation factors to form elongation complex (Mus musculus)


name: peptide transmembrane transporter activity


name: Glutathione is taken up by the bacterium (Homo sapiens)


name: Release of E3 from polyubiquitinated substrate (Mus musculus)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Mus musculus)


name: 3'-tRNA processing endoribonuclease activity


name: acetyl-CoA + 6 H(+) + 6 malonyl-CoA = 6 CO2 + 7 CoA + H2O + naphtopyrone YWA1


name: Phosphorylation and activation of eIF4G by activated S6K1 (Mus musculus)


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Mus musculus)


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Mus musculus)


name: kaempferol + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + quercetin


name: PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Homo sapiens)


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Sus scrofa)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Schizosaccharomyces pombe)


name: NMRK2 phosphorylates NAR to yield NAMN (Dictyostelium discoideum)


name: 3-oxoisoheptadecanoyl-CoA + H(+) + NADPH => 3-hydroxyisoheptadecanoyl-CoA + NADP(+)


name: Dopa is decarboxylated to dopamine (Sus scrofa)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Homo sapiens)


name: 3-hydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine <=> 3-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine


name: CoA + H(+) + malonate => H2O + malonyl-CoA


name: GAB1 phosphorylation by EGFR kinase (Drosophila melanogaster)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Sus scrofa)


name: LC3 binds ATG7 dimer (Schizosaccharomyces pombe)


name: [protein]-C-terminal-L-glutamine + H2O => [protein]-C-terminal-L-glutamate + NH4(+)


name: 3-(3-hydroxyphenyl)pyruvate + L-glutamate => 2-oxoglutarate + 3-hydroxy-L-phenylalanine


name: KDM5A-D demethylate Me2K5-histone H3 (Bos taurus)


name: POU5F1 (OCT4), SOX2, NANOG bind the EOMES promoter (Homo sapiens)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Canis familiaris)


name: Phosphorylation of PLCgamma by PDGFR (Xenopus tropicalis)


name: (R)-benzodiazepinedione + dimethylallyl diphosphate => (2S,3R,11R)-aszonalenin + diphosphate


name: AMP + diphosphate + hexacosanoyl-CoA => ATP + CoA + hexacosanoate


name: guanine + H(+) + H2O => NH4(+) + xanthine


name: Factor D cleaves C3b-bound Factor B (Homo sapiens)


name: FABP5:atRA translocates from cytosol to nucleoplasm (Rattus norvegicus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Gallus gallus)


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + H(+) + S-adenosyl-L-homocysteine => (4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + S-adenosyl-L-methionine


name: (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+) => (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH


name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa (Bos taurus)


name: T-type VDCC bind T-type VDCC blockers (Sus scrofa)


name: INF-gamma induced phosphorylation of L13a (Homo sapiens)


name: perillyl-alcohol dehydrogenase (NAD+) activity


name: FN1 binds Collagen types I-V, VII (Canis familiaris)


name: NT5C3B hydrolyses 7MGP to 7MG (Canis familiaris)


name: Degradation of multiubiquitinated Securin (Mus musculus)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate


name: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine


name: FAD + H(+) + H2O + lithocholate <=> chenodeoxycholate + FADH2


name: H(+) + rifamycin SV + S-adenosyl-L-homocysteine => 27-O-demethylrifamycin SV + S-adenosyl-L-methionine


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: P2Y5 receptor can bind to LPA (Danio rerio)


name: alpha-humulene + O2 + reduced [NADPH--hemoprotein reductase] <=> 10-hydroxy-alpha-humulene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PLC gamma 2-mediated PIP2 hydrolysis (Mus musculus)


name: DENND4s exchange GTP for GDP on RAB10 (Canis familiaris)


name: histamine + S-adenosyl-L-methionine = H(+) + N(tau)-methylhistamine + S-adenosyl-L-homocysteine


name: a long-chain fatty aldehyde + H(+) + 2 NADPH + O2 => a long-chain alkane + formate + H2O + 2 NADP(+)


name: 2 Fe(III)-[cytochrome c3] + H2 <=> 2 Fe(II)-[cytochrome c3] + 2 H(+)


name: Prolactin receptor is internalized (Xenopus tropicalis)


name: 2-methylbutanoyl-CoA + ethanol = CoA + ethyl 2-methylbutanoate


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Drosophila melanogaster)


name: Acyl Ghrelin and C-Ghrelin are secreted (Gallus gallus)


name: 14-3-3 zeta binding allows recruitment of PI3K (Canis familiaris)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Mus musculus)


name: (1S,2S)-1,2-dihydronaphthalene-1,2-diol + NADP(+) = H(+) + NADPH + naphthalene-1,2-diol


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Rattus norvegicus)


name: PRKN polyubiquitinates RIPK3 (Bos taurus)


name: ADP + D-kanosamine 6-phosphate + H(+) => ATP + kanosamine


name: an N-(acyl)-sphingosylphosphocholine(in) + ATP + H2O => ADP + an N-(acyl)-sphingosylphosphocholine(out) + H(+) + phosphate


name: eNOS binds NOSIP (Dictyostelium discoideum)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Sus scrofa)


name: a fatty acyl-CoA + sphinga-4E,14Z-dienine = an N-acyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: glucuronoside transmembrane transporter activity


name: (2E,9Z)-octadecadienoyl-CoA + H2O <=> (3S)-hydroxy-(9Z-octadecenoyl)-CoA


name: p62 is recruited and forms a complex with TRAF6 (Homo sapiens)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Homo sapiens)


name: UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out) = UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in)


name: Activated FGFR3 phosphorylates PPTN11 (Gallus gallus)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Sus scrofa)


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Mus musculus)


name: H(+) + isopentadecanoyl-CoA + malonyl-CoA <=> 3-oxoisoheptadecanoyl-CoA + CO2 + CoA


name: trans-Golgi Network Coat Activation (Schizosaccharomyces pombe)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Dictyostelium discoideum)


name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Schizosaccharomyces pombe)


name: PDPK1 phosphorylates AKT2 (Rattus norvegicus)


name: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + oxidized dithiothreitol <=> 1,4-dithiothreitol + 2,3-epoxyphylloquinone


name: hexacosenoyl-CoA + sphinganine => CoA + H(+) + N-hexacosenoylsphinganine


name: oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor


name: "With a quinone or similar compound as acceptor"


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Saccharomyces cerevisiae)


name: acetyl-CoA + H2O => acetate + CoA + H(+)


name: maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) (Dictyostelium discoideum)


name: ABCC4 accumulation of dense granule contents (Danio rerio)


name: 3'-phosphoadenylyl sulfate + 3beta-hydroxyandrost-5-en-17-one <=> adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate + H(+)


name: GTP + H(+) + phosphoenolpyruvate <=> diphosphate + enolpyruvoyl-2-diphospho-5'-guanosine


name: (ethylene terephthalate)(n) + H2O = (ethylene terephthalate)(n-1) + 4-[(2-hydroxyethoxy)carbonyl]benzoate + H(+)


name: PRLR is phosphorylated at Ser-349 (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Dictyostelium discoideum)


name: Endocytosis of cya:lef:(pagA(197-794):ANTXR1 oligomer) (plasma membrane to endosome membrane) (Homo sapiens)


name: (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + NADH


name: CMP-N-acetyl-beta-neuraminate + N-acetyl-beta-lactosamine <=> CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine


name: 2 (S)-lactate(in) + prostaglandin E1(out) <=> 2 (S)-lactate(out) + prostaglandin E1(in)


name: acetyl-CoA + L-glutamate 5-semialdehyde = CoA + H(+) + N-acetyl-L-glutamate 5-semialdehyde


name: L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase]


name: ADP + D-glucose 6-phosphate + H(+) => ATP + D-glucose


name: cis-zeatin + UDP-alpha-D-glucose => H(+) + O-beta-D-glucosyl-cis-zeatin + UDP


name: GDIs block activation of RHOG (Drosophila melanogaster)


name: MUS81 binds EME1, EME2 (Schizosaccharomyces pombe)


name: G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxy-fatty acyl)-dihydroceramide => a 1,2-diacyl-sn-glycerol + inositol-1-phospho-N-(2-hydroxy-fatty acyl)-dihydroceramide


name: 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O => (Z)-24-ethylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2


name: (R)-carnitine + 2,6-dimethylheptanoyl-CoA => CoA + O-2,6-dimethylheptanoyl-(R)-carnitine


name: 4 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) => 4 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: 3,3',5-trihydroxybibenzyl + 4 CO2 + 4 CoA => 3-(3-hydroxyphenyl)-propanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: WDR5 binds Me2sR3-replicative histone H3 (Caenorhabditis elegans)


name: MAOB:FAD oxidatively deaminates of PEA (Bos taurus)


name: 2 glutathione + NADP(+) => glutathione disulfide + H(+) + NADPH


name: Expression of ZIC1 in the neural plate border (Homo sapiens)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Homo sapiens)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine <=> [(1->4)-N-acetyl-beta-D-glucosaminyl](n+1) + H(+) + UDP


name: GSK3 phosphorylates p-GLI3 (Mus musculus)


name: 1D-myo-inositol 2,3-bisphosphate + H2O => 1D-myo-inositol 2-phosphate + phosphate


name: phycocyanobilin-L-cysteinyl(155)-[C-phycocyanin beta-subunit] => (2R,3E)-phycocyanobilin + apo-L-cysteinyl(155)-[C-phycocyanin beta-subunit]


name: Metallochaperone inserts 2Cu2+ into MT-CO2 (Mus musculus)


name: 3,6-anhydro-L-galactonate + 2 H(+) + NADPH => 3,6-anhydro-alpha-L-galactopyranose + H2O + NADP(+)


name: EXA4 is converted to EXC4 by LTC4S (Mus musculus)


name: Cytoslic carboxylases translocate to mitochondrial matrix (Xenopus tropicalis)


name: 2-oxoglutarate + a methylated nucleobase within DNA + O2 = a nucleobase within DNA + CO2 + formaldehyde + succinate


name: FLVCR1-1 transports heme from cytosol to extracellular region (Drosophila melanogaster)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Rattus norvegicus)


name: (9Z)-hexadecenoate + O2 + reduced [NADPH--hemoprotein reductase] => (9Z)-16-hydroxyhexadec-9-enoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 (3R)-hydroxydecanoyl-[ACP] + H2O => (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + H(+) + 2 holo-[ACP]


name: soyasapogenol B 3-O-beta-D-glucuronate + UDP-alpha-D-galactose => H(+) + soyasaponin III + UDP


name: 3'-phosphoadenylyl sulfate + choline <=> adenosine 3',5'-bisphosphate + choline sulfate + H(+)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Bos taurus)


name: SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP (Mus musculus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Drosophila melanogaster)


name: H2O + inosine <=> D-ribose + hypoxanthine


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Homo sapiens)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Sus scrofa)


name: 5-aminomethyl-dUMP in DNA + acetyl-CoA = 5-acetylaminomethyl-dUMP in DNA + CoA + H(+)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Xenopus tropicalis)


name: 2,3-dihydroxybenzoate + ATP + holo-[ACP] <=> 2,3-dihydroxybenzoyl-[ACP] + AMP + diphosphate


name: a 3-dehydro-D-guloside = a 3-dehydro-D-glucoside


name: SERPING1 variant does not bind factor XIIa (Homo sapiens)


name: (9Z)-octadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-octadecenyl (9Z)-octadecenoate + CoA


name: Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize (Homo sapiens)


name: acetyl-CoA + 6 H(+) + 6 malonyl-CoA => 6 CO2 + 7 CoA + H2O + naphtopyrone YWA1


name: diphosphate + ent-cassa-12,15-diene => ent-copalyl diphosphate


name: Endostatin degradation by cathepsins (Bos taurus)


name: Syndecans 1, 2 & 4 bind VTN (Bos taurus)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Dictyostelium discoideum)


name: Stalling of DNA replication fork and RPA binding (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate <=> (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate


name: Interleukin-1 family precursors are cleaved by caspase-1 (Homo sapiens)


name: H2O + L-asparagine => L-aspartate + NH4(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(out) + ADP + H(+) + phosphate => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(in) + ATP + H2O


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 5-hydroxy-L-tryptophan => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2


name: M6PR transports activated ARSA to the lysosome (Canis familiaris)


name: Activated ATM phosphorylates ABL1 (Bos taurus)


name: chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols (Sus scrofa)


name: Interaction of PECAM-1 and PLC gamma1 (Sus scrofa)


name: EPS15 and HGS bind ubiquitinated MET (Rattus norvegicus)


name: 1H-imidazole + acetyl-CoA <=> CoA + N-acetylimidazole


name: (3S)-hydroxydecanoyl-CoA => (2E)-decenoyl-CoA + H2O


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Canis familiaris)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)


name: (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + AH2 + O2 = (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + A + 2 H2O


name: ALDH3A2-2 oxidizes pristanal to pristanate (Saccharomyces cerevisiae)


name: GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Homo sapiens)


name: acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]


name: D-serine + H2O + O2 = 3-hydroxypyruvate + H2O2 + NH4(+)


name: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine <=> deacetoxyvindoline + H(+) + S-adenosyl-L-homocysteine


name: spermine dialdehyde <=> acrolein + N-(4-aminobutyl)-3-aminopropanal


name: H2 + n sulfur => H(+) + hydrogen sulfide + (n-1) sulfur


name: 3-oxoisoapionate + ATP <=> 3-oxoisoapionate 4-phosphate + ADP + H(+)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Rattus norvegicus)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Xenopus tropicalis)


name: NICD4 traffics to the nucleus (Rattus norvegicus)


name: PXLP-K333-GADL1 decarboxylates CSA to HTAU (Homo sapiens)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Plasmodium falciparum)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Drosophila melanogaster)


name: diphosphate + O-[5'-(adenylyl-(5'->3')-adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein] => ATP + O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein]


name: SAR1 Activation And Membrane Binding (Caenorhabditis elegans)


name: phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A (Homo sapiens)


name: an N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O <=> 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + O2


name: S-adenosyl-L-methionine + TRIBOA beta-D-glucoside = DIMBOA beta-D-glucoside + H(+) + S-adenosyl-L-homocysteine


name: ARL3:GTP binds the UNC119B complex (Bos taurus)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Saccharomyces cerevisiae)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Sus scrofa)


name: 13-cis-retinal + H(+) + NADPH => 13-cis-retinol + NADP(+)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Mus musculus)


name: BRAP binds KSR1:MARK3 (Plasmodium falciparum)


name: Aquaporins passively transport glycerol out of cells (Homo sapiens)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + eicosanoyl-CoA <=> 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA


name: 2 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone <=> 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate


name: IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Canis familiaris)


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Saccharomyces cerevisiae)


name: ATP + Co(2+)(out) + H2O = ADP + Co(2+)(in) + H(+) + phosphate


name: ARHGAP35 stimulates RHOA GTPase activity (Danio rerio)


name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 (Canis familiaris)


name: chenodeoxycholate + glycine = glycochenodeoxycholate + H2O


name: CSKMT methylates Citrate Synthase (Canis familiaris)


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Canis familiaris)


name: Activation of RAC1 by VAV2/3 (Xenopus tropicalis)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NADP(+) = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 H(+) + 8 NADPH


name: nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement (Homo sapiens)


name: E-cadherin degradation by MMP9, KLK7 (Rattus norvegicus)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Bos taurus)


name: 16alpha-hydroxydehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) <=> 16alpha-hydroxydehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: NOTCH1 PEST domain mutants stimulate MYC transcription (Homo sapiens)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Xenopus tropicalis)


name: ADP-1-deoxy-1,O(4)-didehydro-D-ribose + L-arginyl-[protein] = ADP-riboxanated L-argininyl-[protein] + H(+) + NH4(+)


name: H2O + L-ectoine => (2S)-2-acetamido-4-aminobutanoate


name: 16 ATP + 16 H2O + N2 + 8 reduced [2Fe-2S]-[ferredoxin] = 16 ADP + 6 H(+) + H2 + 2 NH4(+) + 8 oxidized [2Fe-2S]-[ferredoxin] + 16 phosphate


name: 2-oxoglutarate + O-phospho-L-serine <=> 3-phosphooxypyruvate + L-glutamate


name: p-STAT1:p-STAT4 translocates to the nucleus (Caenorhabditis elegans)


name: Dissociation of the P2Y purinoceptor 12:Gi complex (Bos taurus)


name: FDPS dimer transfers IPPP to DMAPP (Mus musculus)


name: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine = H(+) + N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine


name: 12,13-epoxy-(9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-12,13-epoxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Danio rerio)


name: RNA polymerase II cis-regulatory region sequence-specific DNA binding


name: TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Homo sapiens)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Canis familiaris)


name: CHSY1 transfers GalNAc to chondroitin (Drosophila melanogaster)


name: USP2 binds the heterodimer of MDM2 and MDM4 (Canis familiaris)


name: 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + diphosphate => ATP + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycerol + H(+) + phosphocholine


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Sus scrofa)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Caenorhabditis elegans)


name: GRKs bind ADRB2:Catecholamine (Canis familiaris)


name: PA is converted to CDP-DAG by CDS1 (Schizosaccharomyces pombe)


name: a 1-acylglycerol + hexadecanoyl-CoA <=> an hexadecanoyl-acylglycerol + CoA


name: oxoglutarate dehydrogenase (NADP+) activity


name: PTK6 phosphorylates STAP2 (Mus musculus)


name: Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol (Homo sapiens)


name: USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Rattus norvegicus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Bos taurus)


name: Nephrin dimer:KIRREL binds FYN (Rattus norvegicus)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA


name: 1,2-didecanoyl-sn-glycerol + ATP => 1,2-didecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: acetyl-CoA + oxalate <=> acetate + oxalyl-CoA


name: (2S)-methylpentadecanoyl-CoA + O2 => 2-methyl-(2E)-pentadecenoyl-CoA + H2O2


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Homo sapiens)


name: Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Sus scrofa)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Homo sapiens)


name: AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA => adenosine(37) in tRNA + L-threonylcarbamoyladenylate


name: Discoidal HDL binds membrane-associated free cholesterol (Homo sapiens)


name: Interaction of PECAM-1 and PLC gamma1 (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid IVA = a 2-acyl-sn-glycero-3-phosphocholine + a lipid IVB


name: CDH11 associates with catenins (Gallus gallus)


name: 2-oxoglutarate + N(2)-acetyl-L-ornithine <=> L-glutamate + N-acetyl-L-glutamate 5-semialdehyde


name: L-Glutamine transport into neurons (Bos taurus)


name: epitestosterone + H(+) + NADPH <=> 5beta-dihydroepitestosterone + NADP(+)


name: cis-1,2-dihydro-3-ethylcatechol + NAD(+) <=> 3-ethylcatechol + H(+) + NADH


name: ESR1 binds ESR1 antagonists (Mus musculus)


name: L-lysyl-L-proline + N-acetyl-L-seryl-L-aspartate => goralatide + H2O


name: SLC29A1 transports RBV from extracellular region to cytosol (Danio rerio)


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Homo sapiens)


name: RAF phosphorylates MAP2K dimer (Caenorhabditis elegans)


name: PDPK1 binds PIP2 (Dictyostelium discoideum)


name: Dissociation of IRS-P from insulin receptor (Canis familiaris)


name: SENP1,2,5 proteolytically process SUMO3 (Dictyostelium discoideum)


name: PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Schizosaccharomyces pombe)


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Sus scrofa)


name: ATP + ethanolamine + L-glutamate => ADP + gamma-L-glutamylethanolamide + H(+) + phosphate


name: 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate => glycyrrhizin + H2O


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Danio rerio)


name: 2-oxoglutarate + 4-(trimethylamino)butanoate + O2 => carnitine + CO2 + succinate


name: 8 H(+) + 10 malonyl-CoA <=> 10 CO2 + 10 CoA + 2 H2O + tetracenomycin F2


name: 17beta-hydroxyestr-4-en-3-one + H(+) + NADPH => 17beta-hydroxy-5beta-estran-3-one + NADP(+)


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Schizosaccharomyces pombe)


name: 3-(carbamoylamino)-2-methylpropanoate + H(+) => 5,6-dihydrothymine + H2O


name: H2O + N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine => L-asparagine + N-acetyl-D-glucosamine


name: 11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione => (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoate


name: 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+)


name: NEU3 hydrolyzes Neu5Ac from glycoconjugates (Xenopus tropicalis)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine


name: AH2 + O2 + protoaustinoid B = A + H2O + preaustinoid A


name: a ganglioside GQ1b (d18:1(4E)) + H2O <=> a ganglioside GT1b (d18:1(4E)) + N-acetylneuraminate


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene + A = 1,1'-dihydroxy-3,4-didehydro-1,2-dihydrolycopene + AH2


name: CDK4 phosphorylates RUNX2 (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + 5,7-dihydroxy-4-methylphthalide => 4-farnesyl-3,5-dihydroxy-6-methylphthalide + diphosphate


name: PARK2 autoubiquitinates (Saccharomyces cerevisiae)


name: 3-(all-trans-decaprenyl)benzene-1,2-diol + H2O + NADP(+) => 2-all-trans-decaprenylphenol + H(+) + NADPH + O2


name: Transhomodimerization of Nectins (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: an alpha-amino acid ester + H2O <=> an alcohol + an alpha-amino acid + H(+)


name: Salvage - Sepiapterin is reduced to BH2 (Bos taurus)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Dictyostelium discoideum)


name: 2 H(+) + H2O + thiocyanate => carbonyl sulfide + NH4(+)


name: OCT3 mediates renal clearance of organic cations (Canis familiaris)


name: 26-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase] = 26-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: CTP + 2 H2O = CMP + 2 H(+) + 2 phosphate


name: Translocation of ERBB4s80 to the nucleus (Sus scrofa)


name: benzoyl-AMP + CoA => AMP + benzoyl-CoA + H(+)


name: RAC2 GAPs stimulate RAC2 GTPase activity (Sus scrofa)


name: phycocyanobilin-L-cysteinyl(84)-[allophycocyanin alpha-subunit] => (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[allophycocyanin alpha-subunit]


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Dictyostelium discoideum)


name: Caspase-mediated cleavage of plectin-1 (Homo sapiens)


name: (6S)-NADPHX + ADP <=> AMP + H(+) + NADPH + phosphate


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate => alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: AMP + beta-D-fructose 1,6-bisphosphate + H(+) => ADP + beta-D-fructose 6-phosphate


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-phenylalanine => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-phenylalanyl-[tubulin] + H2O


name: Activated FGFR2:p-FRS bind to PPTN11 (Homo sapiens)


name: FAD + glutaryl-CoA + 2 H(+) => (2E)-butenoyl-CoA + CO2 + FADH2


name: PP2A methylation by LCMT1 (Xenopus tropicalis)


name: 11-O-acetylcyathatriol + A <=> 11-O-acetylcyathin A3 + AH2


name: p-Y705-STAT3 binds p-Y693-STAT4 (Bos taurus)


name: cAMP induces dissociation of inactive PKA tetramers (Bos taurus)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Bos taurus)


name: NOTCH3 coactivator complex binds DLGAP5 gene promoter (Homo sapiens)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Drosophila melanogaster)


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Caenorhabditis elegans)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (9R)-hydroxy-(10E,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + sn-glycero-3-phospho-1D-myo-inositol <=> H(+) + myo-inositol + sn-glycerol 3-phosphate


name: Release of p-STAT2:p-STAT1 dimer (Homo sapiens)


name: Exocytosis of Proactivator polypeptide (Bos taurus)


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Canis familiaris)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Sus scrofa)


name: Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)


name: 5-N(alpha)-glycyl-dTMP in DNA + AH2 + S-adenosyl-L-methionine => 5'-deoxyadenosine + 5-C(alpha)-glycyl-dTMP in DNA + A + H(+) + L-methionine


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + octanoyl-CoA => 1-O-hexadecyl-2-acetyl-3-octanoyl-sn-glycerol + CoA


name: adenosine 3',5'-bisphosphate + H(+) + O-sulfo-L-tyrosine-[protein] => 3'-phosphoadenylyl sulfate + L-tyrosyl-[protein]


name: glycine(out) + H(+)(in) + Na(+)(out) => glycine(in) + H(+)(out) + Na(+)(in)


name: Degradation of ubiquitinated SMAD3 (Homo sapiens)


name: STAT4 binds IL12RB2:IL12RB2 (Homo sapiens)


name: beta-alanine(out) + n H(+)(in) <=> beta-alanine(in) + n H(+)(out)


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Bos taurus)


name: Dissociation of Cdc20 from APC/C complex (Canis familiaris)


name: GTP + L-lysyl-[protein] => diphosphate + H(+) + N(epsilon)-GMP-L-lysyl-[protein]


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Bos taurus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SFTPA/SFTPD binds TLR2:TLR1 (Homo sapiens)


name: p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs (Homo sapiens)


name: GRK2 sequesters activated Gq (Canis familiaris)


name: (6E)-8-hydroxygeranial + NADP(+) <=> (6E)-8-oxogeranial + H(+) + NADPH


name: an oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> an N-acyl-sphingoid base + an oligoglycosyl-(1->4)-D-glucose


name: chrodrimanin C + H(+) + NADPH + O2 => chrodrimanin H + H2O + NADP(+)


name: 6-deoxo-28-norcastasterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 6alpha-hydroxy-28-norcastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 11-hydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => ferruginol + O2 + reduced [NADPH--hemoprotein reductase]


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Homo sapiens)


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Mus musculus)


name: PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: (4R)-hydroxysphinganine + tetracosanoate => H2O + N-tetracosanoyl-(4R)-hydroxysphinganine


name: G alpha (z) inhibits adenylate cyclase (Xenopus tropicalis)


name: O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2 = 18-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation and release of IRF7 (Homo sapiens)


name: AKT1 binds eNOS complex via HSP90 (Mus musculus)


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate => 2-oxoglutarate + GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: H2O + N(5)-phenyl-L-glutamine <=> aniline + H(+) + L-glutamate


name: CYGB:O2 dissociates (Xenopus tropicalis)


name: an alpha-L-fucoside + H2O => an alcohol + L-fucose


name: Dentin phosphoprotein binds integrin alphaVbeta1 (Bos taurus)


name: H2O + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> H(+) + N-hexadecanoylethanolamine + sn-glycerol 3-phosphate


name: [HPr protein]-L-serine + ATP = [HPr protein]-O-phospho-L-serine + ADP + H(+)


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Xenopus tropicalis)


name: ATP + N-acyl-15-methylhexadecasphing-4-enine = ADP + H(+) + N-acyl-15-methylhexadecasphing-4-enine-1-phosphate


name: RPE65 isomero-hydrolyses atREs to 11cROL (Canis familiaris)


name: NADP(+) + nonan-1-ol <=> H(+) + NADPH + nonanal


name: 1D-myo-inositol 1,2-bisphosphate + H2O => 1D-myo-inositol 2-phosphate + phosphate


name: (24S)-hydroxycholesterol 24-sulfate + 3'-phosphoadenylyl sulfate => (24S)-hydroxycholesterol 3,24-disulfate + adenosine 3',5'-bisphosphate + H(+)


name: 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: ATP + D-galactose(out) + H2O <=> ADP + D-galactose(in) + H(+) + phosphate


name: OCT3 mediates renal clearance of organic cations (Rattus norvegicus)


name: "With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"


name: DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)


name: 4-hydroxy-3-[(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-2-one + H(+) + NADPH + O2 <=> 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H2O + NADP(+)


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Danio rerio)


name: Kinesin-5 is a homotetramer (Caenorhabditis elegans)


name: ATP + L-threonine <=> ADP + H(+) + O-phospho-L-threonine


name: H2O + juvenile hormone I <=> H(+) + juvenile hormone I carboxylate + methanol


name: A + Fe(II)-heme o + H2O = AH2 + Fe(II)-heme i


name: DVL is recruited to the receptor (Rattus norvegicus)


name: 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O => (9Z,12Z)-octadecadienoate + AH2 + O2


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Mus musculus)


name: ACAT1 tetramer acetylates IDH2 dimer (Danio rerio)


name: "Hydron translocation linked to the hydrolysis of diphosphate"


name: STAMBPL1 is a deubiquitinase (Drosophila melanogaster)


name: NTHL1 glycosylase mediated recognition and binding of cytosine glycol (Homo sapiens)


name: Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE (Homo sapiens)


name: H2O + kaempferol 3-O-beta-D-glucoside = beta-D-glucose + kaempferol


name: D-tyrosine + H2O + O2 => 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Drosophila melanogaster)


name: glycine + N-carbamoyl-2-oxoglycine => (S)-2-ureidoglycine + glyoxylate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine


name: CBL binds and ubiquitinates phosphorylated Sprouty (Danio rerio)


name: Collagen type III degradation by MMP14 (Caenorhabditis elegans)


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Mus musculus)


name: SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)


name: cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Rattus norvegicus)


name: H(+)(in) + malonate(out) + phosphate(in) <=> H(+)(out) + malonate(in) + phosphate(out)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-hexanoyl ethanolamine => H2O + N-hexanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine


name: PhosphoChREBP (Thr 653) is exported to cytosol (Rattus norvegicus)


name: (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA + NADP(+)


name: Association of mTERF with the termination sequence (Homo sapiens)


name: 2-oxoglutarate + H(+) <=> CO2 + succinate semialdehyde


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-(9Z-octadecaenoyl)-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + malonyl-CoA <=> (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA + CO2 + CoA


name: 24,25-dihydrolanosterol + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] = 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: LHX2,(LHX9) binds the ROBO3 gene promoter (Homo sapiens)


name: (1S,2S)-1,2-dihydronaphthalene-1,2-diol + NADP(+) <=> H(+) + NADPH + naphthalene-1,2-diol


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Drosophila melanogaster)


name: an N-acyl-D-amino acid + H2O <=> a carboxylate + a D-alpha-amino acid


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Rattus norvegicus)


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Bos taurus)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Homo sapiens)


name: PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body (Danio rerio)


name: (E)-sinapaldehyde + H(+) + NADPH => (E)-sinapyl alcohol + NADP(+)


name: H(+) + NADH + O2 + protoviolaceinate = H2O + NAD(+) + violaceinate


name: 6-hydroxynicotinate + H2O + O2 <=> 2,6-dihydroxynicotinate + H2O2


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Danio rerio)


name: 2 H(+)(out) + L-aspartate(out) => 2 H(+)(in) + L-aspartate(in)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)


name: Phosphorylated SHC1 in complex with ligand-responsive p-6Y-EGFR mutants recruits GRB2:SOS1 complex (Homo sapiens)


name: N(6)-(D-erythrulosyl)-L-lysyl-[protein] + phosphate => H2O + N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein]


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Xenopus tropicalis)


name: ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate => ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate


name: 2'-deoxyuridine + ATP = ADP + dUMP + H(+)


name: a ganglioside GT3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GT2 (d18:1(4E)) + H(+) + UDP


name: AcK685-p-Y705,S727 STAT3 and SIN3A bind the IL2RG promoter (Homo sapiens)


name: chenodeoxycholoyl-CoA + NAD(+) = 7alpha-hydroxy-3-oxochol-24-oyl-CoA + H(+) + NADH


name: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA => acetyl-CoA + vanillin


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Canis familiaris)


name: SPHK1 binds PKR (Caenorhabditis elegans)


name: PPM1D dephosphorylates RUNX2 (Gallus gallus)


name: HGFAC cleaves pro-HGF to form HGF dimer (Rattus norvegicus)


name: WLS dissociates from retromer (Gallus gallus)


name: (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> (R)-mandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Homo sapiens)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen (Homo sapiens)


name: COPII coat binds TRAPPCII and RAB1:GDP (Saccharomyces cerevisiae)


name: ERCC6 binds stalled RNA Pol II (Xenopus tropicalis)


name: GLI1 is degraded by the proteasome after ubiquitination by ITCH (Homo sapiens)


name: JMJD6 demethylates MeR4-HIST1H4 (Gallus gallus)


name: butanoyl-CoA + ethanol = CoA + ethyl butanoate


name: sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen (Rattus norvegicus)


name: 2xPPCS ligates PPanK with Cys (Saccharomyces cerevisiae)


name: alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucuronate => beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: MERTK receptor binds ligands (Gas6 or Protein S) (Xenopus tropicalis)


name: L-aspartate 4-semialdehyde + pyruvate <=> (S)-2,3-dihydrodipicolinate + H(+) + 2 H2O


name: 3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-methionine => H(+) + pterostilbene + S-adenosyl-L-homocysteine


name: butachlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = butyl formate + H2O + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 3-oxo-(5Z-tetradecenoyl)-CoA + CoA <=> (3Z)-dodecenoyl-CoA + acetyl-CoA


name: 3-phenylpyruvate + H(+) <=> 2-phenylacetaldehyde + CO2


name: dGTP(out) + UTP(in) => dGTP(in) + UTP(out)


name: Na(+)(in) + uracil(in) => Na(+)(out) + uracil(out)


name: diphthine methyl ester-[translation elongation factor 2] + H2O <=> diphthine-[translation elongation factor 2] + H(+) + methanol


name: NAD(+) + octanoyl-CoA => (2E)-octenoyl-CoA + H(+) + NADH


name: GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH => GDP-6-deoxy-alpha-D-talose + NADP(+)


name: SULT1A1 dimer sulfonates NHABP (Drosophila melanogaster)


name: (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate => (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glutathione


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2


name: DHI and DHICA polymerize forming eumelanin (Dictyostelium discoideum)


name: 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: a quaternary ammonium(out) + ATP + H2O => a quaternary ammonium(in) + ADP + H(+) + phosphate


name: SLC46A1 transports hemes from extracellular region to cytosol (Caenorhabditis elegans)


name: YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Mus musculus)


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + H(+) + hexanoate


name: 2 Fe(III)-[cytochrome c] + H2O + nitrous oxide => 2 Fe(II)-[cytochrome c] + 2 H(+) + 2 nitric oxide


name: CYP46A1 24-hydroxylates CHOL (Danio rerio)


name: Addition of GlcNAc to position 5 by MGAT5 (Rattus norvegicus)


name: DHFR dimer binds DHFR inhibitors (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: Co-precorrin-3 + H(+) + S-adenosyl-L-homocysteine => Co-precorrin-2 + S-adenosyl-L-methionine


name: H2O + N(6)-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] = H(+) + L-lysyl-[protein] + lactate


name: Nociceptin receptor binds to nociceptin (Homo sapiens)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Caenorhabditis elegans)


name: ALPI dimer hydrolyses phosphate monoesters (Gallus gallus)


name: a ganglioside GD1a (d18:1(4E)) + N-acetylneuraminate => a ganglioside GT1a (d18:1(4E)) + H2O


name: IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments (Canis familiaris)


name: MAOB inhibitors bind MAOB:FAD (Danio rerio)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)


name: 4-methyl-2-oxopentanoate + H(+) <=> 3-methylbutanal + CO2


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O => 2-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Mitochondrial BTD hydrolyses BCTN (Rattus norvegicus)


name: 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine => diphosphate + IMP


name: Phosphorylated STAT1, STAT3 form dimers (Drosophila melanogaster)


name: AFG3L2 binds mitochondrial inner membrane proteins (Gallus gallus)


name: DCC interacts with DIP13alpha (Homo sapiens)


name: AH2 + an N-acyleicosasphinganine + O2 => A + an N-acyleicosasphing-4-enine + 2 H2O


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Danio rerio)


name: p75NTR:NgR complex interacts with the axonal inhibitor LINGO1 (Canis familiaris)


name: PG and CDP-DAG are converted to CL by CRLS1 (Drosophila melanogaster)


name: lithocholoyl-CoA + ursodeoxycholate <=> lithocholate + ursodeoxycholoyl-CoA


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Bos taurus)


name: (2S)-versicolorone + H(+) + NADPH + O2 = (3S)-versiconol acetate + H2O + NADP(+)


name: 2-oxoglutarate + H(+) + O2 + trihazone A = 2 CO2 + H2O + succinate + trihazone D


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Rattus norvegicus)


name: FAR2 reduces PalmCoA to HXOL (Canis familiaris)


name: Aquaporin-1 passively transports water into cell (Rattus norvegicus)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B3)


name: H2O + octanoyl-[ACP] <=> H(+) + holo-[ACP] + octanoate


name: (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH


name: dATP + H2O => 2-deoxyribose 5-triphosphate + adenine


name: PTPN7 dephosphorylates p-T,Y-MAPKs (Mus musculus)


name: a 1,2-diacylglycerol + an all-trans-retinyl ester => a triacylglycerol + all-trans-retinol


name: Dissociation of the SPINK5:KLK5 complex at low pH (Homo sapiens)


name: Phosphorylation of Platelet Sec-1 (Sus scrofa)


name: 26-hydroxyhexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 26-oxohexacosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Canis familiaris)


name: NSL acetylates histone H4 (Drosophila melanogaster)


name: D-ribulose 1-phosphate <=> dihydroxyacetone phosphate + glycolaldehyde


name: PPT2 hydrolyses PALMCoA to PALM (Canis familiaris)


name: AMP + diphosphate + lithocholoyl-CoA => ATP + CoA + lithocholate


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Canis familiaris)


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Saccharomyces cerevisiae)


name: 2,2'-iminodipropanoate + H2O + NAD(+) <=> H(+) + L-alanine + NADH + pyruvate


name: a 1-acyl-sn-glycero-3-phosphate + a fatty acyl-[ACP] = a 1,2-diacyl-sn-glycero-3-phosphate + holo-[ACP]


name: 2 Na(+)(in) + propanoate(in) => 2 Na(+)(out) + propanoate(out)


name: WLS:WNT complex is internalized for maturation into exosomes (Caenorhabditis elegans)


name: CHEK1 phosphorylates RAD51 (Saccharomyces cerevisiae)


name: (1S,4S)-dihydrocarvone + H(+) + NADH => (1S,2R,4S)-neodihydrocarveol + NAD(+)


name: a Fe(III)-siderophore(out) + ATP + H2O = a Fe(III)-siderophore(in) + ADP + H(+) + phosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine => 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Fe-coproporphyrin III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + heme b + 2 L-methionine


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Caenorhabditis elegans)


name: ATP + glutathione(in) + H2O + taurochenodeoxycholate(in) = ADP + glutathione(out) + H(+) + phosphate + taurochenodeoxycholate(out)


name: KDM5A-D demethylate Me3K5-histone H3 (Sus scrofa)


name: dihydroxyacetone phosphate + iminosuccinate <=> H(+) + 2 H2O + phosphate + quinolinate


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Danio rerio)


name: acetyl-CoA + N-terminal L-glutamyl-L-glutamyl-L-glutamyl-[protein] <=> CoA + H(+) + N-terminal N-acetyl-L-glutamyl-L-glutamyl-L-glutamyl-[protein]


name: 3-maleylpyruvate + H2O = H(+) + maleate + pyruvate


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Danio rerio)


name: FLT3LG dimer:FLT3 binds FLT3 (Mus musculus)


name: 3'-dephospho-CoA(in) + AMP(out) <=> 3'-dephospho-CoA(out) + AMP(in)


name: benzyl alcohol + NAD(+) = benzaldehyde + H(+) + NADH


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Bos taurus)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Xenopus tropicalis)


name: PKN1 stimulates association of AR with NCOA2 (Sus scrofa)


name: gamma-L-glutamyl-D-alanine + NH4(+) => D-alanine + L-glutamine


name: 15alpha-stemmadenine intermediate II + H2O <=> (16R)-deshydroxymethyl-stemmadenine + formate


name: Basigin binds Matrix metalloproteinase-1 (Xenopus tropicalis)


name: Interaction of PAK1 with Rac1-GTP (Mus musculus)


name: H(+) + heptadecanoate + hnu => CO2 + hexadecane


name: TP53 family members bind PPP1R13B or TP53BP2 (Bos taurus)


name: RB1 binds condensin II (Dictyostelium discoideum)


name: ABCB1 transports PREDN,PREDL out of hepatic cells (Gallus gallus)


name: 13-cis-retinal + H2O + NAD(+) => 13-cis-retinoate + 2 H(+) + NADH


name: GLTP transports GSL from plasma membrane to ER membrane (Rattus norvegicus)


name: Active ARF recruits coatomer to the Golgi (Mus musculus)


name: (+)-valencene + O2 + reduced [NADPH--hemoprotein reductase] => alpha-nootkatol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Homo sapiens)


name: 2 a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycero-3-phospho-1D-myo-inositol


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Sus scrofa)


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP-beta-L-colitose <=> alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP + H(+)


name: chloride(out) + dopamine(out) + 2 Na(+)(out) => chloride(in) + dopamine(in) + 2 Na(+)(in)


name: bromide + S-adenosyl-L-methionine <=> bromomethane + S-adenosyl-L-homocysteine


name: Release of p-STAT2:p-STAT1 dimer (Sus scrofa)


name: estrone + H(+) + NADH => 17beta-estradiol + NAD(+)


name: 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2 => 3'-N-debenzoyltaxol + A + H2O


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA


name: ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine <=> ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate


name: ADAT1 deaminates adenosine-37 in tRNA(Ala) (Homo sapiens)


name: 1,6-didemethyltoxoflavin + S-adenosyl-L-methionine <=> H(+) + reumycin + S-adenosyl-L-homocysteine


name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] <=> 2-hexadecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl hexadecanoate + apo--[retinol-binding protein]


name: MARC1,MARC2 reduce N-hydroxylated compounds (Bos taurus)


name: (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADP(+) = (22S)-22-hydroxycampest-4-en-3-one + H(+) + NADPH


name: Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Danio rerio)


name: 2 Na(+)(in) + tetrahydroxoborate(in) = 2 Na(+)(out) + tetrahydroxoborate(out)


name: ATP binding to HSP90 triggers conformation change (Bos taurus)


name: ATP + L-glutamate + L-glutamyl-[protein] <=> ADP + gamma-L-glutamyl-L-glutamyl-[protein] + H(+) + phosphate


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Danio rerio)


name: (2E)-geranyl diphosphate + H2O <=> (1S,2S,4R)-endo-fenchol + diphosphate


name: Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Caenorhabditis elegans)


name: Transfer of ubiquitin from E1 to E2 (Drosophila melanogaster)


name: D-tagatopyranose 1-phosphate + NH4(+) => D-galactosamine 6-phosphate + H2O


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Dictyostelium discoideum)


name: Association of Ran-GTP with importin-beta (Homo sapiens)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Xenopus tropicalis)


name: 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+) => 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-L-ribitol


name: Dimerization of KIT upon SCF binding (Sus scrofa)


name: FUNDC1 is phosphorylated by CK2 (Bos taurus)


name: (2E,9Z)-octadecadienoyl-CoA + FADH2 => (9Z)-octadecenoyl-CoA + FAD + H(+)


name: RHOBTB3 hydrolyzes ATP (Drosophila melanogaster)


name: KAT5 acetylates ATM at DNA DSBs (Bos taurus)


name: Anti-MET small tyrosine kinase inhibitors bind MET (Bos taurus)


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Xenopus tropicalis)


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Schizosaccharomyces pombe)


name: AKT phosphorylates PHF20 (Gallus gallus)


name: H(+) + H2O + hydroxyalbendazole + oxidized [NADPH--hemoprotein reductase] => albendazole + O2 + reduced [NADPH--hemoprotein reductase]


name: hydroxylamine + O2 = H(+) + H2O + nitrite


name: Addition of nucleotides between position +11 and +30 (Sus scrofa)


name: chloride(out) + creatine(out) + 2 Na(+)(out) = chloride(in) + creatine(in) + 2 Na(+)(in)


name: [thioredoxin]-dithiol + H2O2 <=> [thioredoxin]-disulfide + 2 H2O


name: (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one + 5-cis-10'-apo-lycopenal => 5-cis-lycopene + O2


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Homo sapiens)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: Recruitment of Rad17-RFC complex to DNA (Schizosaccharomyces pombe)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Drosophila melanogaster)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Bos taurus)


name: NaS2 co-transports sulphate and two sodium ions (Canis familiaris)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Saccharomyces cerevisiae)


name: Phosphorylation of PKC theta (Canis familiaris)


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Rattus norvegicus)


name: guanine + queuosine(34) in tRNA(Tyr) => guanosine(34) in tRNA(Tyr) + queuine


name: cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine => H(+) + N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine


name: 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 (Homo sapiens)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Xenopus tropicalis)


name: (2R,3S)-iso(homo)2citrate + NAD(+) = 2-oxoheptanedioate + CO2 + NADH


name: 1-O-alkyl-2-acyl-sn-glycerol + an acyl-CoA => 1-O-alkyl-2,3-diacyl-sn-glycerol + CoA


name: XDH oxidizes hypoxanthine to form xanthine (Dictyostelium discoideum)


name: L-glutamine(out) + L-serine(in) + Na(+)(out) <=> L-glutamine(in) + L-serine(out) + Na(+)(in)


name: Acidification of Tf:TfR1 containing endosome (Homo sapiens)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Homo sapiens)


name: xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity


name: Insulin binds the insulin receptor (Canis familiaris)


name: Activation of claspin (Drosophila melanogaster)


name: RHOD:GTP translocates to the endosome membrane (Schizosaccharomyces pombe)


name: Receptors CCR1, 2 and 8 bind CCL16 ligand (Bos taurus)


name: PTK2 autophosphorylates downstream of EGFR (Bos taurus)


name: PRKCB (PKC-beta) phosphorylates CARMA1 (Rattus norvegicus)


name: Opsins act as GEFs for G alpha-t (Rattus norvegicus)


name: a 2-methyl-branched fatty aldehyde + H2O + NAD(+) <=> a 2-methyl fatty acid + 2 H(+) + NADH


name: Reduction of presqualene diphosphate to form squalene (Mus musculus)


name: ATP + Fe(III)-enterobactin(out) + H2O => ADP + Fe(III)-enterobactin(in) + H(+) + phosphate


name: IL6R binds IL6R inhibitors (Gallus gallus)


name: 1-(9Z-octadecenoyl)-sn-glycerol + ATP => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: p-STAT5 binds the NOX4 promoter (Homo sapiens)


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Bos taurus)


name: Bacterial GUSB hydrolyses BDG to BIL (Homo sapiens)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Rattus norvegicus)


name: 5 H(+)(in) + menaquinone-8 + NADH = 4 H(+)(out) + menaquinol-8 + NAD(+)


name: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O


name: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + H(+) + S-adenosyl-L-homocysteine


name: Expression of SIX1 in metanephric mesenchyme (Homo sapiens)


name: PLK1 phosphorylates NUDC (Caenorhabditis elegans)


name: Activation of ISG15 by UBA7 E1 ligase (Caenorhabditis elegans)


name: NNT dimer transfers proton from NADPH to NAD+ (Mus musculus)


name: H2O + malonaldehyde + O2 => 3-oxopropanoate + H(+) + H2O2


name: (E)-feruloyl-CoA + tyramine = CoA + H(+) + N-[(E)-feruloyl]tyramine


name: H2 + methanophenazine => dihydromethanophenazine


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Gallus gallus)


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-nonadecanoyl-sn-glycero-3-phosphocholine <=> 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: glycyl-L-histidine + H2O => glycine + L-histidine


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Sus scrofa)


name: sphinga-(4E,8E)-dienine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoylsphinga-(4E,8E)-dienine


name: Defective MPI does not  isomerize Fru6P to Man6P (Homo sapiens)


name: δ12-PGJ3 spontaneously dehydrates to  15d-PGJ3 (Homo sapiens)


name: FITM1, FITM2 bind TAGs (Saccharomyces cerevisiae)


name: Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton (Sus scrofa)


name: (2E)-geranyl diphosphate + 7 isopentenyl diphosphate => all-trans-nonaprenyl diphosphate + 7 diphosphate


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Rattus norvegicus)


name: 5D-5-O-methyl-chiro-inositol + NADP(+) <=> 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH


name: N-acetyl-alpha-neuraminate(out) + 2 Na(+)(out) = N-acetyl-alpha-neuraminate(in) + 2 Na(+)(in)


name: a 2-oxocarboxylate + L-asparagine = 2-oxosuccinamate + an L-alpha-amino acid


name: H2O2 + 2 L-ascorbate => 2 H2O + 2 monodehydro-L-ascorbate radical


name: CBL binds TGFBR2 (Drosophila melanogaster)


name: CYP2F1 dehydrogenates 3-methylindole (Canis familiaris)


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Schizosaccharomyces pombe)


name: O2 + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO


name: chloramphenicol(in) + H(+)(out) => chloramphenicol(out) + H(+)(in)


name: Formation of VAF (virus-activated factor) complex (Sus scrofa)


name: L-alanine + L-glutamate => H2O + L-alanyl-L-glutamate


name: a globoside NORint (d18:1(4E)) + H(+) + UDP => a globoside NOR1 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates (Homo sapiens)


name: a 3alpha-hydroxysteroid + NADP(+) = a 3-oxosteroid + H(+) + NADPH


name: [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + H(+) + NADPH + O2 => [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B + H2O + NADP(+)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 = 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Homo sapiens)


name: NEIL1 cleaves FapyG from damaged DNA (Sus scrofa)


name: SUMOylation of RXRA with SUMO1 (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = a 1-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Danio rerio)


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: pre-VLDL translocates from RER membrane to SER lumen (Gallus gallus)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Canis familiaris)


name: Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Homo sapiens)


name: ERK1/2/5 activate RSK1/2/3 (Schizosaccharomyces pombe)


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: H(+) + phenylglyoxylate => benzaldehyde + CO2


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Cleavage of thymine by TDG glycosylase (Gallus gallus)


name: XDH dehydrogenates xanthine to form urate (Mus musculus)


name: a ubiquinone + H(+) + NADH => a ubiquinol + NAD(+)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Rattus norvegicus)


name: Activation of GIRK/Kir3 Channels (Canis familiaris)


name: creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Homo sapiens)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Sus scrofa)


name: GIP receptor binds gastric inhibitory peptide (Homo sapiens)


name: 2-amino-4-hydroxypteridine + H(+) + H2O => 2,4-dihydroxypteridine + NH4(+)


name: GBF1 recruits ARF:GDP to the Golgi (Plasmodium falciparum)


name: N-acyl-15-methylhexadecasphing-4-enine + phosphate => H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphate


name: SREBP1A,2 binds the MVK promoter (Homo sapiens)


name: The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)


name: HCCS inserts heme into cytochrome c (Bos taurus)


name: dCMP + H(+) + UDP => 2'-deoxycytidine + UTP


name: Recruitment of IRF3 to activated ZBP1:TBK1 (Homo sapiens)


name: aldehydo-D-glucose 6-phosphate + L-lysyl-[protein] => H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein]


name: allyl alcohol + NADP(+) <=> acrolein + H(+) + NADPH


name: Phosphorylated TIM transports from the cytosol to the nucleus (Drosophila melanogaster)


name: Defective ARSB does not hydrolyse C4S/C6S chains (Homo sapiens)


name: chloride(in) + 2 hydrogencarbonate(out) + K(+)(out) => chloride(out) + 2 hydrogencarbonate(in) + K(+)(in)


name: (S)-2-hydroxyglutarate + O2 => 2-oxoglutarate + H2O2


name: p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)


name: Association of Golgi  transport vesicles with microtubules (Mus musculus)


name: L-seryl-[protein] + UDP-alpha-D-xylose <=> 3-O-(beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP


name: L-glutamine(in) + L-methionine(out) + Na(+)(out) <=> L-glutamine(out) + L-methionine(in) + Na(+)(in)


name: ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Bos taurus)


name: Activated FGFR4 binds FRS3 (Homo sapiens)


name: 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+) => 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-glycerol


name: GRKs bind ADRB2:Catecholamine (Rattus norvegicus)


name: alpha,alpha-trehalose 6-phosphate + H(+) + TDP => D-glucose 6-phosphate + TDP-alpha-D-glucose


name: (2S)-ethylmalonyl-CoA + H(+) => butanoyl-CoA + CO2


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Mus musculus)


name: 3-phosphonopyruvate + acetyl-CoA + H2O = (R)-2-(phosphonomethyl)malate + CoA + H(+)


name: chorismate + L-glutamine <=> 4-amino-4-deoxychorismate + L-glutamate


name: CGRP receptor can bind calcitonin gene-related peptides (Gallus gallus)


name: Exocytosis of azurophil granule lumen proteins (Rattus norvegicus)


name: (2S)-2-hydroxy-2-methyl-3,3-dimethylbutanenitrile => 3,3-dimethylbutan-2-one + hydrogen cyanide


name: POLB-mediated DNA strand displacement synthesis (Canis familiaris)


name: PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release (Canis familiaris)


name: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + H(+) + UDP


name: betaine aldehyde + H2O + NADP(+) => glycine betaine + 2 H(+) + NADPH


name: SALM2 associate with AMPA and NMDA receptors (Homo sapiens)


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Caenorhabditis elegans)


name: Influx of extracellular calcium (Homo sapiens)


name: (2E,6E)-farnesol + NAD(+) = (2E,6E)-farnesal + H(+) + NADH


name: PIAS1 SUMOylates SATB1 with SUMO2,3 (Rattus norvegicus)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Sus scrofa)


name: 3-dehydro-6-deoxoteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase]


name: Interaction of nephrin with adherens junction-associated proteins (Homo sapiens)


name: BTRC binds p-S344, 347 NFE2L2 (Rattus norvegicus)


name: Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + succinate


name: Journey of cargo through Golgi complex (Bos taurus)


name: Phosphorylation of PLC-gamma1 (Rattus norvegicus)


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Homo sapiens)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(36-hydroxyhexatriacontenoyl)-sphing-4-enine <=> a diacylglycerol + an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontenoyl)-sphing-4-enine


name: Autoubiquitination of phospho-COP1(Ser-387 ) (Homo sapiens)


name: MPP5 binds SARS-CoV-1 E pentamer (Homo sapiens)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: stevioside + UDP-alpha-D-glucose => H(+) + rebaudioside E + UDP


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Drosophila melanogaster)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) <=> [thioredoxin]-dithiol + glycine + H(+) + phosphate


name: D-arabinose + NAD(+) => D-arabinono-1,4-lactone + H(+) + NADH


name: isopentenyl diphosphate + neryl diphosphate <=> (2Z,6Z)-farnesyl diphosphate + diphosphate


name: MEN1 binds SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: XP-C binds to RAD23B forming a heterodimer (Gallus gallus)


name: 19-(4-hydroxyphenyl)nonadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] => 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates (Homo sapiens)


name: a hydroperoxide + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] => an alcohol + H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: (3S)-hydroxyoctanoyl-CoA + NAD(+) = 3-oxooctanoyl-CoA + H(+) + NADH


name: BRAF autophosphorylates downstream of RAP1 and NGF (Caenorhabditis elegans)


name: alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+) => alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Danio rerio)


name: Excision of FapyG by OGG1 glycosylase (Saccharomyces cerevisiae)


name: Factor I inactivates Factor H-boundC3b (Canis familiaris)


name: 4,8-dimethylnonanoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(4,8-dimethylnonanoyl)-4'-phosphopantetheine


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Canis familiaris)


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Homo sapiens)


name: betaine aldehyde + H2O + NAD(+) = glycine betaine + 2 H(+) + NADH


name: GSK3B phosphorylates p-NFE2L2 (Gallus gallus)


name: Basigin interacts with CD43 (Bos taurus)


name: CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex (Gallus gallus)


name: (R)-2-(phosphonomethyl)malate + CoA + H(+) => 3-phosphonopyruvate + acetyl-CoA + H2O


name: Gap repair completes provirus integration (Homo sapiens)


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Saccharomyces cerevisiae)


name: (9S)-hydroperoxy-(10E,12Z)-octadecadienoate <=> colneleate + H2O


name: (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 => (3R,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: H2O + L-homocarnosine = 4-aminobutanoate + L-histidine


name: Galanin receptors can bind galanin (Gallus gallus)


name: benzaldehyde + glycine => L-threo-3-phenylserine


name: Scaffolding protein CKA binds BSK and phosphorylated HEP kinases (Drosophila melanogaster)


name: a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H2O = a lipid X + 2 H(+) + UMP


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Gallus gallus)


name: cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 <=> albonoursin + H2O2


name: Translocation of activated BAX to the mitochondria (Rattus norvegicus)


name: (2E)-octenoyl-CoA + H2O => (3S)-hydroxyoctanoyl-CoA


name: 4 H(+) + luteothin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = aureothin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: CTP(out) + UDP(in) <=> CTP(in) + UDP(out)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Rattus norvegicus)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Rattus norvegicus)


name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin (Gallus gallus)


name: (9Z,11E)-octadecadienoate + H2O = 10-hydroxy-(11E)-octadecenoate


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A => a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate)


name: Activation of HCN channels (Drosophila melanogaster)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-malate + NADP(+) => H(+) + NADPH + oxaloacetate


name: GMP + H2O <=> D-ribose 5-phosphate + guanine


name: RUNX1 binds the SWI/SNF complex (Mus musculus)


name: SALL4 recruits NuRD to PTEN gene (Bos taurus)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Xenopus tropicalis)


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 <=> CO2 + cylindrospermopsin + succinate


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Bos taurus)


name: 2,5-dioxopentanoate + H2O + NAD(+) => 2-oxoglutarate + 2 H(+) + NADH


name: all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate => all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + H(+) + UDP


name: Fusion of COPII vesicle with Golgi complex (Bos taurus)


name: Cleavage of Procaspase-7 by the apoptosome (Homo sapiens)


name: (S)-lactaldehyde + dihydroxyacetone phosphate => L-rhamnulose 1-phosphate


name: H(+) + NADH + O2 + salicylate => 2,3-dihydroxybenzoate + H2O + NAD(+)


name: Interaction of SHP1 and KIT (Rattus norvegicus)


name: (9Z,12Z,15Z)-octadecatrienamide + glyoxylate => N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine


name: 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + cyclic pyranopterin phosphate + H2O => 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 4 H(+) + molybdopterin


name: Chromokinesins form dimers (Gallus gallus)


name: 3-hydroxybenzoyl-CoA + AMP + diphosphate => 3-hydroxybenzoate + ATP + CoA


name: (+)-malbrancheamide B + bromide + FAD + 2 H(+) <=> (+)-malbrancheamide D + FADH2


name: abieta-7,13-dien-18-ol + O2 + reduced [NADPH--hemoprotein reductase] => abieta-7,13-dien-18,18-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5 AH2 + 2 H(+) + heme b + 4 O2 = 5 A + delta-staphylobilin + Fe(2+) + formaldehyde + 4 H2O


name: CHM binds RGGT (Dictyostelium discoideum)


name: 3-hydroxypropanal + H2O + NADP(+) => 3-hydroxypropanoate + 2 H(+) + NADPH


name: a fatty acid + ATP + CoA => a fatty acyl-CoA + AMP + diphosphate


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Rattus norvegicus)


name: acetate + propanoyl-CoA => acetyl-CoA + propanoate


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 oxidized [adrenodoxin] => (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Drosophila melanogaster)


name: 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + AH2 <=> (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + A


name: Rev multimer-bound HIV mRNA associates with Crm1 (Homo sapiens)


name: IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Canis familiaris)


name: T1R1/T1R3 dimer is the umami taste receptor (Canis familiaris)


name: Integrin alphaXbeta2 binds JAM3 (Bos taurus)


name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex (Rattus norvegicus)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Saccharomyces cerevisiae)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: aclacinomycin N + O2 => aclacinomycin A + H2O2


name: (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Rattus norvegicus)


name: F-actin capping protein is a heterodimer (Schizosaccharomyces pombe)


name: a globoside NORint (d18:1(4E)) + UDP-alpha-D-galactose <=> a globoside NOR2 (d18:1(4E)) + H(+) + UDP


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Homo sapiens)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+) => beta-D-fructose 6-phosphate + GDP-alpha-D-mannose


name: Recruitment of p190RhoGEF to p-FAK (Gallus gallus)


name: 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA


name: NMRK2 phosphorylates NR to yield NMN (Mus musculus)


name: all-trans-4,4'-diaponeurosporene + 3 FADH2 => 15-cis-4,4'-diapophytoene + 3 FAD + 3 H(+)


name: Nuclear translocation of catalytic domain of Mst3 (Saccharomyces cerevisiae)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Danio rerio)


name: (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] => (+)-6-endo-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: RUNX1 and ELF1, ELF2 or PAX5 bind the BLK gene promoter (Homo sapiens)


name: S-adenosyl-L-methionine + uridine(341) in tmRNA = 5-methyluridine(341) in tmRNA + H(+) + S-adenosyl-L-homocysteine


name: PTK6 phosphorylates KHDRBS1 (Bos taurus)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Mus musculus)


name: but-3-yn-1-ol + pyrroloquinoline quinone => but-3-ynal + H(+) + pyrroloquinoline quinol


name: (2E,6E)-farnesyl diphosphate => alpha-himachalene + diphosphate


name: 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate


name: ADP + alpha-D-glucose 1-phosphate + H(+) <=> ADP-alpha-D-glucose + phosphate


name: Latent TGF-beta-1 binds integrins (Mus musculus)


name: L-threonate + NAD(+) = 3-dehydro-D-erythronate + H(+) + NADH


name: RNF152 polyubiquitinates RRAGA (Xenopus tropicalis)


name: benzoic acid glucosyltransferase activity


name: D-arginine(in) + L-ornithine(out) => D-arginine(out) + L-ornithine(in)


name: complement component C1q complex binding


name: 3'-phosphoadenylyl sulfate + UDP-N-acetyl-alpha-D-galactosamine 4-sulfate = adenosine 3',5'-bisphosphate + H(+) + UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate


name: acetyl-CoA + alpha-D-galactosamine 1-phosphate => CoA + H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate


name: an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + 3 S-adenosyl-L-methionine = an N,N,N-trimethylornithine lipid + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: TGN-lysosomal vesicle coat assembly (Sus scrofa)


name: 2 Fe(III)-[cytochrome c] + S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein]


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Bos taurus)


name: 17beta-estradiol 17-sulfate(out) + 2 Na(+)(out) => 17beta-estradiol 17-sulfate(in) + 2 Na(+)(in)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Canis familiaris)


name: a 16alpha-hydroxysteroid + NAD(+) <=> a 16-oxosteroid + H(+) + NADH


name: H(+)(out) + L-phenylalanyl-L-phenylalanine(out) = H(+)(in) + L-phenylalanyl-L-phenylalanine(in)


name: a 1-acyl-sn-glycero-3-phosphocholine + H2O => a fatty acid + H(+) + sn-glycerol 3-phosphocholine


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)


name: Release of 40S and 60S subunits from the 80S ribosome  (Dictyostelium discoideum)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Sus scrofa)


name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen


name: CSF3 dimer:CSFR binds CSFR (Xenopus tropicalis)


name: 2-methoxy-4-vinylphenol + H(+) + NADH <=> 4-ethyl-2-methoxyphenol + NAD(+)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Schizosaccharomyces pombe)


name: L1-FGFR cis-heterodimerization (Homo sapiens)


name: BH2 binding can lead to eNOS uncoupling (Mus musculus)


name: ABCA4 mediates atRAL transport (Caenorhabditis elegans)


name: Dissociation of the Gi alpha:G olf complex (Rattus norvegicus)


name: ARFGAPs stimulate ARF GTPase activity (Schizosaccharomyces pombe)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Caenorhabditis elegans)


name: Activated AR binds RUNX2 (Canis familiaris)


name: D-sedoheptulose 7-phosphate = 2-epi-valiolone + phosphate


name: (2S)-2-hydroxyphytanate + O2 => 2-oxophytanate + H2O2


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Sus scrofa)


name: RAS proteins are depalmitoylated (Canis familiaris)


name: 1-(2-aminophenyl)decane-1,3-dione = 2-heptyl-4(1H)-quinolone + H2O


name: (2E)-butenoyl-CoA + H2O => (3R)-3-hydroxybutanoyl-CoA


name: GAB1 phosphorylation by EGFR kinase (Canis familiaris)


name: dihydrocarvone + H(+) + NADH => dihydrocarveol + NAD(+)


name: RANKL,sRANKL trimer binds RANK (Mus musculus)


name: NADP(+) + prenol <=> 3-methyl-2-butenal + H(+) + NADPH


name: dihydroxyacetone phosphate + glyceraldehyde 3-phosphate <=> fructose 1,6-bisphosphate (Gallus gallus)


name: RHOF GAPs stimulate RHOF GTPase activity (Drosophila melanogaster)


name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Canis familiaris)


name: YAP1 binds ZO-2 (TJP2) (Canis familiaris)


name: glutathione + leukotriene A4 => leukotriene C4


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Danio rerio)


name: Elongation of Extended Telomeric Chromosome End (Mus musculus)


name: IL10 negatively regulates plasma membrane-associated inflammatory mediators (Homo sapiens)


name: a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)


name: Inactivation of Rho-GTP by p190RhoGAP (Caenorhabditis elegans)


name: Activation of EPACs by cAMP (Dictyostelium discoideum)


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Xenopus tropicalis)


name: an aldehyde + FMN + 2 H(+) + H2O + sulfite => an alkanesulfonate + FMNH2 + O2


name: Association of procollagen type I (Danio rerio)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Sus scrofa)


name: GNRHR binds GNRHR peptide antagonists (Canis familiaris)