name: Interaction of DAP12 and KIR3DS1 (Sus scrofa)


name: ADP + H(+) + O-phospho-L-homoserine => ATP + L-homoserine


name: CD28 homodimer binds B7-2 monomer (Homo sapiens)


name: ATP + H(+) + L-arginine <=> diphosphate + L-arginyl-AMP


name: RPE65 isomero-hydrolyses atREs to 11cROL (Xenopus tropicalis)


name: (2E)-geranyl diphosphate = (4E,6E)-allo-ocimene + diphosphate


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Bos taurus)


name: 5alpha-androstan-3,17-dione + H(+) + NADPH => 17beta-hydroxy-5alpha-androstan-3-one + NADP(+)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)


name: D-fructose + UDP-alpha-D-glucose <=> H(+) + sucrose + UDP


name: Deubiquitination of FancD2 (Gallus gallus)


name: Elastin cross-linking by lysyl oxidase (Mus musculus)


name: PAK phosphorylates p21 RAF1 on S338 (Drosophila melanogaster)


name: STAT1,STAT3,STAT6 bind IL13:IL13R type II (Homo sapiens)


name: FLT3LG dimer:FLT3 binds FLT3 (Sus scrofa)


name: 15-demethylaclacinomycin T + AH2 + O2 = 10-decarboxymethylaclacinomycin T + A + CO2 + H2O


name: ATP + gamma-L-glutamyl-L-glutamyl-[tubulin] + L-glutamate => ADP + H(+) + L-glutamyl-gamma-L-glutamyl-L-glutamyl-[tubulin] + phosphate


name: 3,4-dihydroxybenzoate + 2 H(+) + NADH + O2 <=> benzene-1,2,4-triol + CO2 + H2O + NAD(+)


name: ATP + D-tagatofuranose 6-phosphate <=> ADP + D-tagatofuranose 1,6-bisphosphate + H(+)


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Sus scrofa)


name: lyso-ornithine lipid acyltransferase activity


name: HSD11B2 dehydrogenates PREDL to PREDN (Xenopus tropicalis)


name: trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Mus musculus)


name: L-isoleucine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (1E,2S)-2-methylbutanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 3-amino-2-hydroxy-4-methoxybenzoate + ATP + nitrite = AMP + cremeomycin + diphosphate + H2O


name: Caspase-mediated cleavage of GAS2 (Canis familiaris)


name: 1-propanol + acetyl-CoA <=> CoA + propyl acetate


name: IFNG dimer binds IFNG inhibitors (Sus scrofa)


name: H2O + phenylacetonitrile => (Z)-phenylacetaldehyde oxime


name: BRAP binds KSR1:MARK3 (Dictyostelium discoideum)


name: MAPK4,6 translocate to the cytoplasm (Plasmodium falciparum)


name: Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol (Homo sapiens)


name: (S)-2,3-epoxysqualene + H2O => arabidiol


name: dodecanal + H2O + O2 = dodecanoate + H(+) + H2O2


name: 2-oxoglutarate + L-arginine = 5-guanidino-2-oxopentanoate + L-glutamate


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Gallus gallus)


name: dehydroprobetaenone I + 3 H(+) + 3 NADPH + 3 O2 => betaenone C + 3 H2O + 3 NADP(+)


name: (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H2O => (3R)-hydroxy-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Rattus norvegicus)


name: Autophosphorylation of LYN kinase (Bos taurus)


name: Spermine  => N-acetylated spermine (Canis familiaris)


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Homo sapiens)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Plasmodium falciparum)


name: TLE recruits HDAC1 to WNT promoters (Homo sapiens)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Xenopus tropicalis)


name: adenosine 3',5'-bisphosphate(in) + AMP(out) = adenosine 3',5'-bisphosphate(out) + AMP(in)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate => H2O + kynurenate


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: OPLAH hydrolyses OPRO to L-Glu (Bos taurus)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Canis familiaris)


name: 7,8-dihydromonapterin + 2 H(+) + 3 phosphate => 7,8-dihydromonapterin 3'-triphosphate + 3 H2O


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Danio rerio)


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)


name: betaenone B + 3 H2O + 3 NADP(+) => 3 H(+) + 3 NADPH + 3 O2 + probetaenone I


name: p-STAT1 dimerizes (Drosophila melanogaster)


name: TPI1 isomerizes GA3P to DHAP (Danio rerio)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Xenopus tropicalis)


name: 3-hydroxybenzyl alcohol + benzoyl-CoA = 3-hydroxy-benzyl benzoate + CoA


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Rattus norvegicus)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Saccharomyces cerevisiae)


name: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] => an (omega-1)-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Homo sapiens)


name: L-arginine + S-adenosyl-L-methionine <=> H(+) + N(omega)-methyl-L-arginine + S-adenosyl-L-homocysteine


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)


name: 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+) => 3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O2


name: MAPKAPK5 phosphorylates KALRN (Mus musculus)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Saccharomyces cerevisiae)


name: a dolichyl D-xylosyl phosphate + L-seryl-[protein] => 3-O-(beta-D-xylosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)


name: (3,5-dihydroxyphenyl)acetyl-CoA + O2 <=> 2-(3,5-dihydroxyphenyl)-2-oxoacetate + CoA + H(+)


name: a thymidine(6-4)thymidine in DNA => a thymidine dimer in DNA


name: H(+) + N,N-dihydroxy-L-dihomomethionine => (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O


name: PTK6 phosphorylates DOK1 (Caenorhabditis elegans)


name: 3'-phosphoadenylyl sulfate + a phenol => adenosine 3',5'-bisphosphate + an aryl sulfate + H(+)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + H2O = 1-O-(1Z-alkenyl)-sn-glycerol + phosphate


name: Dissociation of Cdc20 from APC/C complex (Gallus gallus)


name: 2-dehydro-D-glucose + H(+) + NADPH => D-mannose + NADP(+)


name: lutein + O2 => (3R)-hydroxy-beta-ionone + (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal


name: glycine + 3 S-adenosyl-L-methionine = glycine betaine + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: ATP + H2O + nitrate(out) => ADP + H(+) + nitrate(in) + phosphate


name: (9Z)-hexadecenoate + H2O <=> 10-hydroxyhexadecanoate


name: inositol tetrakisphosphate kinase activity


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Danio rerio)


name: Ubiquitinated geminin is degraded by the proteasome (Bos taurus)


name: GLUT1 tetramer binds 4xATP (Caenorhabditis elegans)


name: H2O + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] => N(alpha)-acetyl-L-methionine + N-terminal L-glutamyl-[protein]


name: POM121 and NDC1 bind the Nup93 complex (Rattus norvegicus)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Saccharomyces cerevisiae)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA <=> 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside = an anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-[(6-O-(E)-4-coumaroyl)glucoside] + CoA


name: CoA + H(+) + pentanoate => H2O + pentanoyl-CoA


name: Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Canis familiaris)


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Gallus gallus)


name: Formation of the Spliceosomal P complex and exon ligation (Rattus norvegicus)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Sus scrofa)


name: PDCD1 binds PDCD1 inhibitors (Canis familiaris)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Danio rerio)


name: RANBP2 SUMOylates TOP2A with SUMO1 (Homo sapiens)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-alpha-D-glucose => delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP


name: (2E,13Z)-eicosadienoyl-CoA + H(+) + NADPH => (13Z)-eicosenoyl-CoA + NADP(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2 H2O => 2 (9Z)-octadecenoate + 2 H(+) + sn-glycerol 3-phosphocholine


name: H(+) + N-tetracosanoyl-(4R)-hydroxysphinganine + NADPH + O2 => H2O + N-(2-hydroxytetracosanoyl)-(4R)-hydroxysphinganine + NADP(+)


name: RHOD:GTP translocates to the endosome membrane (Caenorhabditis elegans)


name: ST3GAL2,3 transfer Neu5Ac to gangliosides (Mus musculus)


name: SLC34A3 cotransports Pi, 2Na+ (Sus scrofa)


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Rattus norvegicus)


name: a 2-acyl-sn-glycerol 3-phosphate + H2O <=> a 2-acylglycerol + phosphate


name: CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP (Homo sapiens)


name: RHOF GAPs stimulate RHOF GTPase activity (Canis familiaris)


name: ADP + H(+) + phosphate + vincristine(out) => ATP + H2O + vincristine(in)


name: Activated FGFR1 binds PLCG1 (Gallus gallus)


name: AMP + H(+) + nonanoyl-CoA => CoA + nonanoyl-AMP


name: Hemoglobin A is protonated and carbamated causing release of oxygen (Mus musculus)


name: a 1-acyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: L-aspartate + O2 <=> H2O2 + iminosuccinate


name: p-STAT3 dimerizes (Drosophila melanogaster)


name: USP7 deubiquitinates TP53 and counteracts MDM2 (Rattus norvegicus)


name: L-aspartate + menaquinone-8 = iminosuccinate + menaquinol-8


name: chenodeoxycholate + D-glucose => beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O


name: bromide + L-tyrosine + NADP(+) => 3-bromo-L-tyrosine + NADPH


name: p-S225-SPHK1 localizes to cytosol (Caenorhabditis elegans)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 = A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Caenorhabditis elegans)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+) => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP


name: Phosphorylated ERF translocates to the cytosol (Drosophila melanogaster)


name: ERCC1:XPF cleaves flaps generated by SSA (Mus musculus)


name: decanoate ester + H2O => an aliphatic alcohol + decanoate + H(+)


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Canis familiaris)


name: (9Z)-hexadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) <=> (9Z)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: Phosphorylation of STAT1 at Ser727 (Gallus gallus)


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Mus musculus)


name: cyclohexane-1,3-dione + H2O => 5-oxohexanoate + H(+)


name: adenosine 3',5'-bisphosphate(out) + FMN(in) => adenosine 3',5'-bisphosphate(in) + FMN(out)


name: carnitine transmembrane transporter activity


name: a triacyl-sn-glycerol(in) <=> a triacyl-sn-glycerol(out)


name: Basigin binds MCT1, MCT3 and MCT4 (Caenorhabditis elegans)


name: SLC22A1 transports Cipro into renal cell (Sus scrofa)


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Homo sapiens)


name: (3R)-piperidine-3-carboxamide + H2O = (3R)-piperidine-3-carboxylate + NH4(+)


name: Autophosphorylation of LYN kinase (Sus scrofa)


name: H(+) + NADH + oxomalonate => hydroxymalonate + NAD(+)


name: Inactivation of LCK by PTPN22 (Mus musculus)


name: ATP2B4 binds to NOS1, inhibiting it (Dictyostelium discoideum)


name: 1-deoxy-11beta-hydroxypentalenate + NAD(+) <=> 1-deoxy-11-oxopentalenate + H(+) + NADH


name: 18-hydroxy-9,10-epoxy-(12Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9,10-epoxy-(12Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Homo sapiens)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Caenorhabditis elegans)


name: RAC1 binds effectors at the ER membrane (Gallus gallus)


name: abieta-7,13-dien-18-oate + 2 H(+) + NADH => abieta-7,13-dien-18-al + H2O + NAD(+)


name: Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Canis familiaris)


name: ADP + glutathione(out) + glycochenodeoxycholate(out) + H(+) + phosphate => ATP + glutathione(in) + glycochenodeoxycholate(in) + H2O


name: PARP1 ADP-ribosylates SMAD3 and SMAD4 (Rattus norvegicus)


name: Autocatalytic phosphorylation of FGFR2b (Drosophila melanogaster)


name: Insertion of correct bases opposite the lesion by POLH (Canis familiaris)


name: WWTR1 binds SMAD2/3:SMAD4 heterotrimer (Canis familiaris)


name: proton-dependent oligopeptide secondary active transmembrane transporter activity


name: 4-chlorobenzoate + ATP + CoA = 4-chlorobenzoyl-CoA + AMP + diphosphate


name: DAP12 interacts with NKG2C (Canis familiaris)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Sus scrofa)


name: an adenosine in tRNA + CO2 + formaldehyde + succinate => 2-oxoglutarate + an N(1)-methyladenosine in tRNA + O2


name: C-ter TLR7 dimer binds imiquimod (Homo sapiens)


name: H2O + N(2)-(4-aminobutanoyl)-L-ornithine => 4-aminobutanoate + L-ornithine


name: NEDD4L ubiquitinates SMAD2/3 (Drosophila melanogaster)


name: H(+)(in) + 2 nitrate(in) => H(+)(out) + 2 nitrate(out)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Sus scrofa)


name: biphenyl-2,3-diol + H2O + NAD(+) => biphenyl-2-ol + H(+) + NADH + O2


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Gallus gallus)


name: Heterodimerization of CEACAMs (Homo sapiens)


name: Translocation of PLC-gamma1 to PIP2 (Danio rerio)


name: ADP + H(+) + phosphate + putrescine(in) => ATP + H2O + putrescine(out)


name: UHRF1:Chromatin binds DNMT1 (Homo sapiens)


name: D-arabinose 5-phosphate <=> D-ribulose 5-phosphate


name: 12-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 12,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Saccharomyces cerevisiae)


name: C-terminal Hh fragments are bound by lectins (Mus musculus)


name: PTPN18 binds ERBB2:EGFR heterodimers (Rattus norvegicus)


name: Translocation of ERBB4s80 to the nucleus (Homo sapiens)


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] => 2-heptanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl heptanoate + apo--[retinol-binding protein]


name: tBID binds to inactive BAK protein (Gallus gallus)


name: glycine + H2O + xanthurenate => 3-hydroxy-L-kynurenine + glyoxylate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine => H(+) + hexadecanoyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: ABCB9 transports peptides from cytosol to lysosomal lumen (Bos taurus)


name: 4,8-dimethylnonanoyl-CoA + H2O <=> 4,8-dimethylnonanoate + CoA + H(+)


name: chloride(out) + Na(+)(out) <=> chloride(in) + Na(+)(in)


name: 1-O-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + glutarate + H(+)


name: IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)


name: (2E)-butenoyl-[ACP] + H2O => (3R)-hydroxybutanoyl-[ACP]


name: H2O + validoxylamine A 7'-phosphate <=> phosphate + validoxylamine A


name: TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis (Homo sapiens)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Dictyostelium discoideum)


name: 24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 32-hydroxy-24,25-dihydrolanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] <=> N(alpha)-acetyl-L-methionine + N-terminal L-glutamyl-[protein]


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Rattus norvegicus)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Canis familiaris)


name: Binding of ERp57 (Caenorhabditis elegans)


name: DNMT3A binds Me2sR4-HIST1H4 (Canis familiaris)


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,3-di-(9Z-octadecenoyl)-glycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol


name: SPAM1 Binds Hyaluronic Acid (Mus musculus)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Plasmodium falciparum)


name: 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH => NADP(+) + prephenate


name: RhCG mediates ammonium efflux out of kidney collecting duct cells (Canis familiaris)


name: Binding of CBL to EGFR (Drosophila melanogaster)


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Canis familiaris)


name: (2Z,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate


name: PP2A demethylation by PPME1 (Canis familiaris)


name: 1-O-(1Z-hexadecenyl)-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+) => 1-O-(1Z-hexadecenyl)-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH


name: Small molecule inhibitor binds RIPK1, RIPK3 (Homo sapiens)


name: MTA is cleaved and phosphorylated (Xenopus tropicalis)


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Bos taurus)


name: Abortive initiation after formation of the first phosphodiester bond (Canis familiaris)


name: 1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O => 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: Phosphorylated PER transports from the cytosol to the nucleus (Drosophila melanogaster)


name: 3-hydroxybenzoate + pyruvate => chorismate


name: (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + CO2 + CoA


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Sus scrofa)


name: (2E)-but-2-enoyl-AMP + holo-[ACP] = (2E)-butenoyl-[ACP] + AMP + H(+)


name: ZFPM proteins bind GATA proteins (Danio rerio)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation  (Homo sapiens)


name: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2


name: alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ (Caenorhabditis elegans)


name: catechol + O2 = cis,cis-muconate + 2 H(+)


name: HLCS biotinylates 6xMCCC1:6xMCCC2 (Homo sapiens)


name: LAIR2 binds collagen (Rattus norvegicus)


name: a long-chain fatty acid(out) <=> a long-chain fatty acid(in)


name: calcitetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (1S)-1,25-dihydroxy-24-oxocalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: GPI-mannose ethanolamine phosphate phosphodiesterase activity


name: lithocholoyl-24-O-(beta-D-glucuronate) + UDP => lithocholate + UDP-alpha-D-glucuronate


name: Formation of eEF1B complex (Saccharomyces cerevisiae)


name: AXIN is ubiquitinated by SMURF2 (Sus scrofa)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate = (2R)-3-phosphoglycerate + alpha-D-glucose 1,6-bisphosphate + H(+)


name: ATP + H2O + leukotriene C4(out) <=> ADP + H(+) + leukotriene C4(in) + phosphate


name: acetyl-CoA + an omega-(methylsulfanyl)-2-oxoalkanoate + H2O = a 2-(omega-methylsulfanyl)alkylmalate + CoA + H(+)


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Homo sapiens)


name: Crk binds to the active PDGF receptor (Danio rerio)


name: (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol <=> 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA


name: PC carboxylates PYR to OA (Homo sapiens)


name: NDST1-4 N-deacetylates GlcNAc residues in heparan (Danio rerio)


name: Activated FGFR1 phosphorylates FRS3 (Caenorhabditis elegans)


name: PAKs phosphorylate MLC (Caenorhabditis elegans)


name: 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + NADP(+)


name: a 5'-end diphospho-adenosine in mRNA + GTP + H(+) => a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + diphosphate


name: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Plasmodium falciparum)


name: (2S,4S)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine = (2S)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Homo sapiens)


name: Assembly of the anterograde IFT train (Sus scrofa)


name: 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] + 6 CO2 + 7 CoA => acetyl-CoA + 6 H(+) + holo-[ACP] + 6 malonyl-CoA


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Canis familiaris)


name: De novo formation of eIF2:GTP (Canis familiaris)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Dictyostelium discoideum)


name: p-PKR dimer phosphorylates ILF3:ILF2 (Rattus norvegicus)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Xenopus tropicalis)


name: ATP + L-amino acyl-L-seryl-[protein] = (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + ADP + H(+) + phosphate


name: SLC2A9 transports Fru, Glc, urate (Sus scrofa)


name: AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Homo sapiens)


name: CHRNA9:CHRNA10 binds acetylcholine (Homo sapiens)


name: (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + H2O + 2 oxidized [adrenodoxin] => 5beta-cholestane-3alpha,7alpha,12alpha-triol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: SUMOylation of XPC with SUMO1 (Sus scrofa)


name: KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Mus musculus)


name: SLC22A12 exchanges extracellular urate for cytosolic LACT (Sus scrofa)


name: Na(+)(out) + O-butanoyl-(R)-carnitine(out) = Na(+)(in) + O-butanoyl-(R)-carnitine(in)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Gallus gallus)


name: H2O + N-formyl-L-kynurenine => formate + H(+) + L-kynurenine


name: acetyl-CoA + dodecanedioyl-CoA => 3-oxotetradecanedioyl-CoA + CoA


name: Unknown kinase phosphorylates NICD4 (Homo sapiens)


name: NR1H4 binds DCA, CDCA, LCHA (Bos taurus)


name: O-GlcNAcylation of RIPK3 (TLR4 signaling) (Rattus norvegicus)


name: DOLPP1 dephosphorylates DOLDP to DOLP (Bos taurus)


name: SKI complexes with the Smad complex, suppressing BMP2 signalling (Bos taurus)


name: MAP1LC3B binds KEAP1 and SQSTM1 (Dictyostelium discoideum)


name: glutarate(in) + prostaglandin F2alpha(out) => glutarate(out) + prostaglandin F2alpha(in)


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Rattus norvegicus)


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Schizosaccharomyces pombe)


name: 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Xenopus tropicalis)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] => acetyl-CoA + N-terminal L-seryl-[histone H2A]


name: AZD1979 + H2O => AZD1979 oxetane hydrolysis product + H(+)


name: FRK phosphorylates PTEN (Xenopus tropicalis)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + ouabain <=> dihydroouabain + 2 Fe(III)-[cytochrome c]


name: Association of DFF40 with chromatin (Canis familiaris)


name: [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 H(+) + 28 UDP => beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP-alpha-D-galactofuranose


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Schizosaccharomyces pombe)


name: 2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine <=> 2-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine


name: diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate


name: L-lysyl-5'-AMP + tRNA(Lys) <=> AMP + H(+) + L-lysyl-tRNA(Lys)


name: H2O + N-terminal L-tryptophanyl-L-alpha-aminoacyl-[peptide] <=> L-tryptophan + N-terminal L-alpha-aminoacyl-[peptide]


name: transmembrane receptor protein serine/threonine kinase binding


name: PMM1,2 isomerise Man6P to Man1P (Saccharomyces cerevisiae)


name: Caspase cleavage of DCC (Canis familiaris)


name: Defective GALNT3 does not transfer GalNAc to mucins (Homo sapiens)


name: IL35 binds IL6ST:IL6ST receptor (Rattus norvegicus)


name: (S)-2-methyl-3-oxopropanoate + CoA + NAD(+) => CO2 + NADH + propanoyl-CoA


name: acetyl-CoA + oxalate = acetate + oxalyl-CoA


name: SLC29A1 transports RBV from cytosol to extracellular region (Bos taurus)


name: 4-guanidinobutanoate + L-ornithine => 4-aminobutanoate + L-arginine


name: S-adenosyl-L-methionine + uridine(747) in 23S rRNA => 5-methyluridine(747) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Canis familiaris)


name: IRE1 binds IRE1 forming dimer (Xenopus tropicalis)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (R)-octopamine = (4-hydroxyphenyl)acetaldehyde + NH4(+)


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Bos taurus)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Saccharomyces cerevisiae)


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Saccharomyces cerevisiae)


name: NUDT16 hydrolyses IDP to IMP (Danio rerio)


name: I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Bos taurus)


name: 2-hydroxybenzoyl-CoA + malonyl-CoA = 4-hydroxycoumarin + CO2 + 2 CoA


name: LRRC16A binds F-actin capping protein (Caenorhabditis elegans)


name: 2-oxoglutarate + L-lysyl-[protein] + O2 => (3S)-3-hydroxy-L-lysyl-[protein] + CO2 + succinate


name: adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine


name: ITPA hydrolyses XTP to XMP (Dictyostelium discoideum)


name: H2O + N-octadecanoyl-(4R)-hydroxysphinganine = (4R)-hydroxysphinganine + octadecanoate


name: Role of myosins in phagosome formation (Gallus gallus)


name: NTPDase4 hydrolyzes nucleoside diphosphates (Rattus norvegicus)


name: Beta-catenin is released from the destruction complex (Mus musculus)


name: Conversion of Glycerol to Glycerol-3-phosphate (Drosophila melanogaster)


name: 2,3-epoxyphylloquinone + [protein]-dithiol => [protein]-disulfide + H2O + phylloquinone


name: Association of procollagen type I (Bos taurus)


name: SLC25A10 mediates exchange of malate and phosphate (Saccharomyces cerevisiae)


name: B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac (Xenopus tropicalis)


name: STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Canis familiaris)


name: Autophosphorylation of PDGF alpha receptors (Danio rerio)


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Caenorhabditis elegans)


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Gallus gallus)


name: dUTP + H2O => dUMP + pyrophosphate (Xenopus tropicalis)


name: SLC25A1 exchanges CIT and MAL (Danio rerio)


name: estrone 3-sulfate(out) + n H(+)(out) = estrone 3-sulfate(in) + n H(+)(in)


name: Recruitment of SYK to p-DAP12 (Canis familiaris)


name: H2O + phenylglyoxylyl-CoA <=> CoA + H(+) + phenylglyoxylate


name: factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) (Xenopus tropicalis)


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Mus musculus)


name: cholesterol + PAPS => cholesterol sulfate + PAP (Danio rerio)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Caenorhabditis elegans)


name: TRPs transport extracellular Ca2+ to cytosol (Gallus gallus)


name: acetyl-CoA + 6 H(+) + 5 malonyl-CoA + 2 NADPH => 2-hydroxy-5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 3 H2O + 2 NADP(+)


name: 3 H2O + hydrogen sulfide + 3 NADP(+) = 4 H(+) + 3 NADPH + sulfite


name: "assimilatory sulfite reductase (NADPH)"


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Dictyostelium discoideum)


name: H2O + NAD(+) + pentanal <=> 2 H(+) + NADH + pentanoate


name: STUB1 (CHIP) ubiquitinates SMAD3 (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + di-trans,poly-cis-dolichol => a 1-acyl-sn-glycero-3-phosphocholine + acyldolichol


name: Orexin 2 receptor can bind orexin-B neuropeptide (Sus scrofa)


name: Translocation of BMF to mitochondria (Bos taurus)


name: ATP + hydrogencarbonate + tetracosanoyl-CoA = 2-carboxytetracosanoyl-CoA + ADP + H(+) + phosphate


name: NPAS4 binds INS gene promoter (Homo sapiens)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Dictyostelium discoideum)


name: AR binds AR agonists (Xenopus tropicalis)


name: 20-hydroxyecdysone 22-phosphate + H2O = 20-hydroxyecdysone + phosphate


name: Ligand-independent dimerization of PDGFR mutants (Homo sapiens)


name: 1-heptadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-heptadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: Dephosphorylation of pL1 (Y1176) (Homo sapiens)


name: p-Y-STAT3 binds p-STAT5 (Dictyostelium discoideum)


name: Secretion of SOD3 (Schizosaccharomyces pombe)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Caenorhabditis elegans)


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Mus musculus)


name: ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Gallus gallus)


name: fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Sus scrofa)


name: Activated thrombin (factor IIa) cleaves PAR3,4, activating them (Gallus gallus)


name: NADP(+) + prostaglandin D2 <=> 15-oxoprostaglandin D2 + H(+) + NADPH


name: DEGS2 oxygenates dihydroceramide (Caenorhabditis elegans)


name: (25R)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25R)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SLC25A12,13 exchange L-Glu and L-Asp (Xenopus tropicalis)


name: adenosine + H(+) + H2O <=> inosine + NH4(+)


name: (6Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Gallus gallus)


name: CBP and p300 binds NF-kB complex (Mus musculus)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Schizosaccharomyces pombe)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine <=> 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: (4Z,15Z)-bilirubin IXalpha + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = biliverdin IXalpha + reduced coenzyme F420-(gamma-L-Glu)(n)


name: 2,6,10,14-tetramethylpentadecanal + H2O + NAD(+) <=> 2,6,10,14-tetramethylpentadecanoate + 2 H(+) + NADH


name: H(+) + NADH + ubiquinone-10 => NAD(+) + ubiquinol-10


name: butan-1-ol + hexanoyl-CoA <=> butyl hexanoate + CoA


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)


name: (R)-carnitine + 4-(trimethylamino)butanoyl-CoA = (R)-carnitinyl-CoA + 4-(trimethylamino)butanoate


name: alpha-D-mannose 1-phosphate + GTP + H(+) <=> diphosphate + GDP-alpha-D-mannose


name: LZTFL1 binds the BBSome and prevents its traffic to the cilium (Bos taurus)


name: ZnT3 transports zinc into synaptic vesicles (Homo sapiens)


name: USP34 deubiquitinates AXIN1,AXIN2 (Gallus gallus)


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Mus musculus)


name: an acyl-CoA + sn-glycero-3-phosphoethanolamine => a monoacyl-sn-glycero-3-phosphoethanolamine + CoA


name: USP7 deubiquitinates TP53 and counteracts MDM2 (Drosophila melanogaster)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] = akuammicine + formate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NEXT3 is cleaved to produce NICD3 (Xenopus tropicalis)


name: Translocation of PKC theta to plasma membrane (Mus musculus)


name: 4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Danio rerio)


name: TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) (Homo sapiens)


name: 3-oxohexanoyl-CoA + CoA => acetyl-CoA + butanoyl-CoA


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Canis familiaris)


name: acetyl-CoA + anthranilate <=> CoA + N-acetylanthranilate


name: (2E,6E)-farnesyl diphosphate + H2O = diphosphate + trichobrasilenol


name: AUF1 binds translation and heat shock proteins (Sus scrofa)


name: PGM2:Mg2+ isomerises R1P to R5P (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Bos taurus)


name: 2-methyl-3-oxopropanoate + CoA + H2O + NAD(+) <=> H(+) + hydrogencarbonate + NADH + propanoyl-CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol <=> 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: H(+) + NADP(+) + 2 reduced [rubredoxin] <=> NADPH + 2 oxidized [rubredoxin]


name: H(+) + NADH + zerumbone => 10-hydroxy-alpha-humulene + NAD(+)


name: Caspase-mediated cleavage of Desmoglein 2 (Gallus gallus)


name: hydrogen cyanide + piperonal = (2S)-2-(2H-1,3-benzodioxol-5-yl)-2-hydroxyacetonitrile


name: [protein]-dithiol + 2 AH2 + H(+) + sulfite => [protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide


name: Trimming of peptides in ER (Xenopus tropicalis)


name: AcCho is hydrolyzed to Cho and acetate by ACHE (Dictyostelium discoideum)


name: MARK4 binds ODF2 in the centriole (Homo sapiens)


name: NADH + 2 O2 <=> H(+) + NAD(+) + 2 superoxide


name: a lactoside III(4)-a-Fuc-Lc4Cer + GDP-beta-L-fucose => a lactoside IV(2),III(4)-a-[Fuc]2-Lc4Cer + GDP + H(+)


name: AGRP gene expression is stimulated by FOXO1 (Homo sapiens)


name: 3-(pyrazol-1-yl)-L-alanine + H2O => L-serine + pyrazole


name: 4alpha-formylzymosterol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 <=> 4alpha-carboxyzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O <=> C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Mus musculus)


name: (2E)-geranyl diphosphate <=> beta-pinene + diphosphate


name: H2O + hexanal + NADP(+) => 2 H(+) + hexanoate + NADPH


name: SUMOylation of DDX5 with SUMO1 (Bos taurus)


name: HTR1A binds HTR1A agonists (Gallus gallus)


name: LONP1 binds mitochondrial inner membrane proteins (Homo sapiens)


name: (2E)-hexadecenoyl-[ACP] + H2O => (3R)-hydroxyhexadecanoyl-[ACP]


name: (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA + NAD(+) = 3,22-dioxochol-4-en-24-oyl-CoA + H(+) + NADH


name: histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen (Homo sapiens)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Rattus norvegicus)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Bos taurus)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Danio rerio)


name: Thiosulfate can transfer its sulfur atom to glutathione (Bos taurus)


name: RAC1 GEFs activate RAC1 (Caenorhabditis elegans)


name: a 1,3-diacylglycerol + H2O => a 1-acyl-sn-glycerol + a fatty acid + H(+)


name: demethylphylloquinol + S-adenosyl-L-methionine => H(+) + phylloquinol + S-adenosyl-L-homocysteine


name: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate


name: H(+) + malonyl-CoA + S-anthraniloyl-L-cysteinyl-[PqsD protein] => (2-aminobenzoyl)acetyl-CoA + CO2 + L-cysteinyl-[PqsD protein]


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + tetradecanoyl-CoA => 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: 2-oxoglutarate(out) + maleate(in) => 2-oxoglutarate(in) + maleate(out)


name: A + cannabigerolate => AH2 + cannabichromenate


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Bos taurus)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: Deubiquitinated PTEN translocates to the cytosol (Rattus norvegicus)


name: RHOB binds effectors on endosomes (Sus scrofa)


name: TFB1M dimethylates adenosine-936 and adenosine-937 of 12S rRNA yielding 6-dimethyladenosine-936 and 6-dimethyladenosine-937 (Homo sapiens)


name: Activation of cytosolic AMPK by phosphorylation (Rattus norvegicus)


name: Formation of PRC2-EZH2 complex (Drosophila melanogaster)


name: (+)-secoisolariciresinol + NADP(+) => (-)-lariciresinol + H(+) + NADPH


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (8Z,11Z,14Z)-eicosatrienoate => 1-hexadecanoyl-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol


name: H(+) + NADH + propanal => 1-propanol + NAD(+)


name: NaS1 co-transports sulphate and a sodium ion (Mus musculus)


name: 2-oxoglutarate + an alkane-alpha,omega-diamine = an omega-aminoaldehyde + L-glutamate


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Sus scrofa)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Mus musculus)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Rattus norvegicus)


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Sus scrofa)


name: fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 (Homo sapiens)


name: (3R)-citramalyl-CoA + succinate => (3R)-citramalate + succinyl-CoA


name: UROS transforms HMB to URO3 (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-6-sulfoquinovose => a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H(+) + UDP


name: GUSB tetramer hydrolyses CS/HS precursor (Mus musculus)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Sus scrofa)


name: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Rattus norvegicus)


name: MLNR (GPR38) is a receptor for motilin (Sus scrofa)


name: an alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+) => an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate


name: (S)-2-chloropropanoate + NADP(+) => 2-chloroacrylate + H(+) + NADPH


name: 11-cis-retinal--[retinol-binding protein] + H(+) + NADH => 11-cis-retinol--[retinol-binding protein] + NAD(+)


name: 2 H(+) + H2O + N-carbamoylsarcosine <=> CO2 + NH4(+) + sarcosine


name: 2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen


name: 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+)


name: p-S10 CDKN1B translocates to the cytosol (Mus musculus)


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Drosophila melanogaster)


name: (2R,3S)-beta-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Sus scrofa)


name: genistein + O2 + reduced [NADPH--hemoprotein reductase] => 2'-hydroxygenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MDM2 polyubiquitinates RUNX3 (Mus musculus)


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Canis familiaris)


name: (R)-dihydrolipoamide + acetyl-CoA <=> (R)-S(6)-acetyldihydrolipoamide + CoA


name: ADP + glutathione(out) + H(+) + phosphate + tauroursodeoxycholate(out) => ATP + glutathione(in) + H2O + tauroursodeoxycholate(in)


name: a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GM2 + H(+) + UDP


name: dAMP(out) + phosphate(in) <=> dAMP(in) + phosphate(out)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Homo sapiens)


name: Release of CSK from SRC (Drosophila melanogaster)


name: SLCO4C1 mediates the transport of digoxin (Xenopus tropicalis)


name: a (3R)-hydroxyacyl-[ACP] + L-ornithine <=> a lyso-ornithine lipid + H(+) + holo-[ACP]


name: RBX1:CUL3 dissociates from forming autophagosome (Mus musculus)


name: PTGIR binds PTGIR agonists (Xenopus tropicalis)


name: Inhibition of integrin activation by sequestering PIP5KIgamma (Rattus norvegicus)


name: 2-oxoglutarate + L-proline + O2 => CO2 + succinate + trans-4-hydroxy-L-proline


name: E2F6 binds RAD51 gene promoter (Homo sapiens)


name: DEGS1 dehydrogenates dihydroceramide (Homo sapiens)


name: TTLLs polyglutamylate tubulin (Bos taurus)


name: PANK4 hydrolyzes PPANT to pantetheine (Bos taurus)


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Xenopus tropicalis)


name: 9beta-pimara-7,15-dien-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-dien-19-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: acetylglucosamine-inositol-phosphate is dephosphorylated (Mycobacterium tuberculosis)


name: cytidine(839) in 12S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(839) in 12S rRNA + S-adenosyl-L-homocysteine


name: ATP + H2O + tauroursodeoxycholate(in) = ADP + H(+) + phosphate + tauroursodeoxycholate(out)


name: a ribonucleoside 5'-phosphate + 2 H(+) + 2 phosphate => a ribonucleoside 5'-triphosphate + 2 H2O


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Mus musculus)


name: acetyl-CoA + 5 H(+) + holo-[ACP] + 5 malonyl-CoA = 3,5,7,9,11-pentaoxododecanoyl-[ACP] + 5 CO2 + 6 CoA


name: AICAR + 10-Formyl-THF => FAICAR + THF (Schizosaccharomyces pombe)


name: IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation  (Rattus norvegicus)


name: 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine => 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + S-adenosyl-L-methionine


name: LTA4 is converted to EXA4 by ALOX15 (Mus musculus)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Sus scrofa)


name: ATP + L-seryl-[protein] <=> ADP + H(+) + O-phospho-L-seryl-[protein]


name: 2-hydroxyphytanoyl-CoA + CO2 + succinate => 2-oxoglutarate + O2 + phytanoyl-CoA


name: a fatty acid + H(+) + sn-glycero-3-phospho-1D-myo-inositol => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: H(+) + hispidin + NADH + O2 => 3-hydroxyhispidin + H2O + NAD(+)


name: (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate <=> (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate


name: an R-cob(III)alamin + apo-[alkylcobalamin reductase] + glutathione => an S-substituted glutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+)


name: H2O + hexan-2-amine + NAD(+) = H(+) + hexan-2-one + NADH + NH4(+)


name: H(+)(out) + L-histidine(out) => H(+)(in) + L-histidine(in)


name: PDE4A hydrolyses cAMP to AMP (Drosophila melanogaster)


name: N-acetyl-alpha-D-glucosamine 1-phosphate <=> N-acetyl-D-glucosamine 6-phosphate


name: LMF1,2 transport LIPC dimer from ER lumen to extracellular region (Homo sapiens)


name: NADP(+) + scytalone => H(+) + NADPH + naphthalene-1,3,6,8-tetrol


name: an N-carbamoyl-L-alpha-amino acid + 2 H(+) + H2O <=> an L-alpha-amino acid + CO2 + NH4(+)


name: a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-galactose => a 1,2-diacyl-3-O-[alpha-D-galactopyranosyl-(1->2)-alpha-D-glucopyranosyl]-sn-glycerol + H(+) + UDP


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Caenorhabditis elegans)


name: histidine => urocanate + NH4+ (Danio rerio)


name: acetyl-CoA + dopamine => CoA + H(+) + N-acetyl-dopamine


name: (2E)-geranyl diphosphate + isopentenyl diphosphate <=> (2Z,6E)-farnesyl diphosphate + diphosphate


name: ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Homo sapiens)


name: ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus (Gallus gallus)


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Mus musculus)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Rattus norvegicus)


name: glycyl-L-proline(out) + H(+)(out) <=> glycyl-L-proline(in) + H(+)(in)


name: TNIPs bind TNFAIP3 (A20) (Rattus norvegicus)


name: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + H(+) + NADPH + O2 <=> [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + H2O + NADP(+)


name: Interaction of E3 ligase with ISG15:E2 complex (Caenorhabditis elegans)


name: aurachin B + H(+) + H2O <=> 3,4-dihydroxy-2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide


name: L-Glutamate binds GRM1 (mGluR1) (Homo sapiens)


name: K+-independent Li+/Ca2+ exchanger transport (Caenorhabditis elegans)


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Rattus norvegicus)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Rattus norvegicus)


name: p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Rattus norvegicus)


name: estrone + PAPS => estrone 3-sulfate + PAP (Mus musculus)


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Xenopus tropicalis)


name: 3-phosphonopyruvate + H(+) = CO2 + phosphonoacetaldehyde


name: Formation of Cyclin E:Cdk2 complexes (Homo sapiens)


name: ATP + D-alanine + holo-[D-alanyl-carrier protein] <=> AMP + D-alanyl-[D-alanyl-carrier protein] + diphosphate


name: HSD17B3-like proteins reducde ANDST to TEST (Caenorhabditis elegans)


name: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine = 3',4',5-trihydroxy-3,7-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: an n-alkanal + NADP(+) <=> an alk-2-enal + H(+) + NADPH


name: ESCRT Disassembly (Schizosaccharomyces pombe)


name: KIR2DL4 interacting with HLA-G (Homo sapiens)


name: glutarate(in) + kynurenate(out) = glutarate(out) + kynurenate(in)


name: 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP-alpha-D-glucose => an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside + H(+) + UDP


name: 2 N(omega)-hydroxy-L-arginine + NADPH + 2 O2 <=> H(+) + 2 H2O + 2 L-citrulline + NADP(+) + 2 nitric oxide


name: SUMOylation of XPC with SUMO1 (Mus musculus)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Caenorhabditis elegans)


name: [phosphate](n) + D-glucose => [phosphate](n-1) + D-glucose 6-phosphate + H(+)


name: The Immunoglobulin of the BCR binds antigen (Bos taurus)


name: 3-methoxybenzoate + ATP + H(+) + NADPH => 3-methoxybenzaldehyde + AMP + diphosphate + NADP(+)


name: (2R,3R)-dihydroquercetin + H(+) + NADPH + O2 = (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Rattus norvegicus)


name: (5R)-5-hydroxy-L-lysyl-[collagen] + H2O2 + L-methionyl-[collagen] <=> [collagen]-(5R)-5-hydroxy-L-lysyl-N-S-L-methionyl-[collagen] + H(+) + 2 H2O


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Rattus norvegicus)


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Homo sapiens)


name: H(+)(in) + lactose(out) => H(+)(out) + lactose(in)


name: ATR activation at DNA DSBs (Canis familiaris)


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Mus musculus)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: (9Z-octadecenoyl)-glycerol + phosphate => (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O


name: IGF1R phosphorylates SHC1 (Homo sapiens)


name: Association of Ku heterodimer with viral DNA ends (Homo sapiens)


name: 6-sulfo-D-quinovose + FMNH2 + O2 => 6-dehydro-D-glucose + FMN + 2 H(+) + H2O + sulfite


name: Melanin-concentrating hormone receptors bind MCH (Gallus gallus)


name: Aquaporins passively transport water into cells (Schizosaccharomyces pombe)


name: Association of LBP with LPS (Gallus gallus)


name: Loss of SAR1B GTPase (Caenorhabditis elegans)


name: 3-methyl-(2E)-butenoyl-CoA + H2O => 3-hydroxyisovaleryl-CoA


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate


name: HMGCR dimer reduces bHMG-CoA to MVA (Mus musculus)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O = (14R,15R)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: Uncoupled eNOS favours the formation of superoxide (Dictyostelium discoideum)


name: p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + H2O => (-)-alpha-acorenol + diphosphate


name: phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity


name: Hyperphosphorylated IRAK1 associates with TRAF6 (Sus scrofa)


name: 1D-5-O-methyl-myo-inositol + NAD(+) => 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH


name: MET dimers autophosphorylate (Homo sapiens)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Mus musculus)


name: RAC2 translocates to the phagocytic vesicle membrane (Danio rerio)


name: IL12B:IL23A translocates from ER lumen to extracellular space (Sus scrofa)


name: (S)-2-hydroxyglutarate + a quinone <=> 2-oxoglutarate + a quinol


name: L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH


name: Latent TGF-beta-1 is cleaved by FURIN (Drosophila melanogaster)


name: DeHA hydrolyses to threonate and oxalate (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate


name: dodecanoyl-CoA + H(+) + malonyl-CoA = 3-oxotetradecanoyl-CoA + CO2 + CoA


name: 6 Fe(II)-[cytochrome c] + 8 H(+) + nitrite => 6 Fe(III)-[cytochrome c] + 2 H2O + NH4(+)


name: [protein]-dithiol + NADP(+) => [protein]-disulfide + H(+) + NADPH


name: (3R,6R)-6-hydroxy-3-isopropenylheptanoate + H(+) => (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Homo sapiens)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Drosophila melanogaster)


name: p-S54-PDE4B hydrolyses cAMP (Xenopus tropicalis)


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Rattus norvegicus)


name: 2-oxoglutarate + a 1,N(6)-etheno-2'-deoxyadenosine in single-stranded DNA + H2O + O2 = a 2'-deoxyadenosine in single-stranded DNA + CO2 + glyoxal + succinate


name: a 1-acyl-sn-glycerol + an acyl-CoA => a 1,2-diacyl-sn-glycerol + CoA


name: ALOX5 oxidises 15S-HpETE to LXA4/B4 (Bos taurus)


name: Formation of ADAR1 homodimer (Homo sapiens)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Homo sapiens)


name: RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160  (Homo sapiens)


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O = 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + H(+) + phosphate


name: EGFR binds EGF ligand (Rattus norvegicus)


name: FITM1, FITM2 bind TAGs (Xenopus tropicalis)


name: 2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O


name: JAK1 binds IL4R in IL4-bound IL4R1 (Gallus gallus)


name: SENP1,2,5 proteolytically process SUMO1 (Homo sapiens)


name: a 3-oxo-fatty acyl-CoA + H(+) + NADPH => a 3-hydroxy-fatty acyl-CoA + NADP(+)


name: hexadecanoyl-CoA + octadecan-1-ol = CoA + octadecanyl hexadecanoate


name: a 1-acyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-acyl-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: sphinganine 1-phosphate(in) => sphinganine 1-phosphate(out)


name: gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling


name: CHRM1,3,5 bind acetylcholine (Sus scrofa)


name: Protonated weak acid translocates across the plasma membrane (Homo sapiens)


name: 2xPDKX:2xZn2+ phosphorylates PDX (Schizosaccharomyces pombe)


name: FA core complex:HSP70s binds PKR (Gallus gallus)


name: PARVB interacts with Alpha-actinin (Canis familiaris)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Sus scrofa)


name: H2O + N(1)-(3-aminopropyl)agmatine = spermidine + urea


name: FA core complex assembles at DNA interstrand crosslinks (ICLs) (Canis familiaris)


name: H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate => 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate


name: H(+) + NAD(+) + 2 superoxide => NADH + 2 O2


name: FN1 binds Collagen types I-V, VII (Rattus norvegicus)


name: Recruitment of transition zone proteins (Gallus gallus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP + H2O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dUMP


name: NDST1-4 N-deacetylates GlcNAc residues in heparan (Drosophila melanogaster)


name: ATG7:ATG3:LC3 dissociates (Rattus norvegicus)


name: (2S)-sakuranetin + O2 + reduced [NADPH--hemoprotein reductase] <=> (2S)-7-methylcarthamidin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTENP1 mRNA binds miR-20 RISC (Homo sapiens)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Bos taurus)


name: PTPN1 and PTPN2 dephosphorylate MET (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: (2R,5R)-isopulegone + NADP(+) <=> (6R)-isopiperitenone + H(+) + NADPH


name: p-Y348-SYK phosphorylates VAV family (Homo sapiens)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Mus musculus)


name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription (Homo sapiens)


name: high-density lipoprotein particle binding


name: PSIP1 binds MEN1 associated with MLL2 complex (Rattus norvegicus)


name: Translocation of PKC theta to plasma membrane (Dictyostelium discoideum)


name: 7-beta-hydroxysteroid dehydrogenase (NADP+) activity


name: ATP + L-seryl-[rhodopsin] = ADP + H(+) + O-phospho-L-seryl-[rhodopsin]


name: (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit] => phycoviolobilin-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit]


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Dictyostelium discoideum)


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Saccharomyces cerevisiae)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sphing-4-enine <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + sphing-4-enine


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Mus musculus)


name: Grb7 binds to the active PDGF receptor (Sus scrofa)


name: Exocytosis of azurophil granule lumen proteins (Bos taurus)


name: factor VII -> factor VIIa (Homo sapiens)


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate


name: Recruitment of VAV1 to p-6Y-SYK (Rattus norvegicus)


name: 3-hydroxyisopentadecanoyl-CoA + NADP(+) <=> 3-oxoisopentadecanoyl-CoA + H(+) + NADPH


name: E2F6 binds TFDP1 (Drosophila melanogaster)


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Homo sapiens)


name: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 <=> 2 vanillin


name: PIAS1 SUMOylates DDX5 with SUMO2 (Homo sapiens)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Homo sapiens)


name: RIP2 induces K63-linked ubiquitination of NEMO (Mus musculus)


name: FAHD1 dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Xenopus tropicalis)


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] => (S)-eriodictyol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Homo sapiens)


name: Active Rac1 interacts with Plexin-B1:Sema4D (Homo sapiens)


name: Na+/H+ exchanger transport (at cell membrane) (Dictyostelium discoideum)


name: RHOC GAPs stimulate RHOC GTPase activity (Homo sapiens)


name: Activation of Talin (Caenorhabditis elegans)


name: SFKs phosphorylate PLCG1 (Rattus norvegicus)


name: extracellular matrix constituent conferring elasticity


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Drosophila melanogaster)


name: (9Z)-octadecen-1-ol + 1-hexadecanoylglycerone 3-phosphate = 1-O-(9Z)-octadecenylglycerone 3-phosphate + H(+) + hexadecanoate


name: uridine(31) in tRNA => pseudouridine(31) in tRNA


name: KLRC1:KLRD1 heterodimer interacts with HLA-E (Gallus gallus)


name: a 1,2-diacyl-sn-glycerol + a sterol = a 1-acyl-sn-glycerol + a sterol ester


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)


name: REST binds promoter and the first intron of NPAS4 gene (Homo sapiens)


name: Interaction of Tie2 and Shp2 (Rattus norvegicus)


name: a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + 4 H2O + 3 NAD(+) => a 3beta-hydroxy-4,4-dimethylsteroid + 2 H(+) + 3 NADH + 3 O2


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: ATP + H2O + phosphinate(out) = ADP + H(+) + phosphate + phosphinate(in)


name: a dicarboxylate(in) + indoxyl sulfate(out) = a dicarboxylate(out) + indoxyl sulfate(in)


name: ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 (Canis familiaris)


name: PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Homo sapiens)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Danio rerio)


name: PEX7 binds cargo proteins containing PTS2 (Gallus gallus)


name: ME3 tetramer decarboxylates MAL to PYR (Sus scrofa)


name: pppGp(2'-5')A = 2',3'-cGAMP + diphosphate


name: 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+) => 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O


name: Disassociation of PLC-gamma1 from LAT (Homo sapiens)


name: (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O = (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate


name: 2'-O-methyluridine(1369) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(1369) in 16S rRNA


name: sequestered tissue factor -> tissue factor (Danio rerio)


name: Activation of conventional Protein Kinase C (Homo sapiens)


name: BESTs transport cytosolic HCO3- to extracellular region (Mus musculus)


name: 2 caldariellaquinol + n H(+)(in) + O2 => 2 caldariellaquinone + n H(+)(out) + 2 H2O


name: H(+) + NADH + O2 + pyrrole-2-carboxylate = 5-hydroxypyrrole-2-carboxylate + H2O + NAD(+)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Plasmodium falciparum)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Mus musculus)


name: H(+) + L-proline betaine + NADH + O2 => formaldehyde + H2O + N-methyl-L-proline + NAD(+)


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Sus scrofa)


name: B3GNT5 transfers GlcNAc to LacCer (Xenopus tropicalis)


name: (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Xenopus tropicalis)


name: (2S)-5,5-dimethyl-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + 2 H(+) + NADPH => (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + NADP(+)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Saccharomyces cerevisiae)


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Homo sapiens)


name: diphosphate + isoelisabethatriene => (2E,6E,10E)-geranylgeranyl diphosphate


name: beta-D-mannopyranosyl-(1->2)-D-mannopyranose + phosphate <=> alpha-D-mannose 1-phosphate + D-mannose


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Drosophila melanogaster)


name: L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)


name: p-PKR dimer phosphorylates SNCA (Rattus norvegicus)


name: hexadecanal dehydrogenase (acylating) activity


name: 2-methylpropanenitrile + H2O => (Z)-2-methylpropanal oxime


name: GPIb-IX-V binds to vWF:Collagen complex (Gallus gallus)


name: isorhamnetin + S-adenosyl-L-methionine = H(+) + rhamnacene + S-adenosyl-L-homocysteine


name: Transhomodimerization of Nectin-like (Necl) proteins (Canis familiaris)


name: ABL1 phosphorylates YAP1 (Canis familiaris)


name: 1-O-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + succinate


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Danio rerio)


name: an L-alpha-amino acid + ATP + L-arginine = ADP + H(+) + L-arginyl-L-alpha-amino acid + phosphate


name: "L-arginine-specific L-amino acid ligase"


name: 8-demethyl-8-formylriboflavin 5'-phosphate + A + H2O => 8-carboxy-8-demethylriboflavin 5'-phosphate + AH2 + H(+)


name: a secondary alcohol + NADP(+) => a ketone + H(+) + NADPH


name: CTP + pseudaminate <=> CMP-pseudaminate + diphosphate


name: 2-(L-cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = camalexin + CO2 + 2 H(+) + 4 H2O + hydrogen cyanide + 2 oxidized [NADPH--hemoprotein reductase]


name: a 2,3-dehydroacyl-CoA + AH2 => A + a 2,3-saturated acyl-CoA


name: ATP + histamine + L-glutamate = ADP + H(+) + N(alpha)-gamma-L-glutamylhistamine + phosphate


name: RBP3 transports 11cRAL to rod photoreceptor outer segment (Homo sapiens)


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Rattus norvegicus)


name: H2O + L-tryptophan + NAD(+) = H(+) + indole-3-pyruvate + NADH + NH4(+)


name: PRKCZ recruits RAS in response to estrogen stimulation (Bos taurus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + 2 S-adenosyl-L-homocysteine => a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine


name: STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Bos taurus)


name: 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose <=> (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + H(+) + UDP


name: (2Z,6Z)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Drosophila melanogaster)


name: ethylamine + N-isopropylammelide => H(+) + H2O + hydroxyatrazine


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Rattus norvegicus)


name: (E)-pent-2-en-1-ol + NADP(+) => (E)-2-pentenal + H(+) + NADPH


name: 2-oxoglutarate + H2O2 => (S)-2-hydroxyglutarate + O2


name: NAD(+) + resolvin D1 = 8-oxoresolvin D1 + H(+) + NADH


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Caenorhabditis elegans)


name: a 3-oxo-Delta(5)-steroid + H(+) + NADH => a 3beta-hydroxy-Delta(5)-steroid + NAD(+)


name: HEXB cleaves the terminal GalNAc from small HA fragments (Xenopus tropicalis)


name: H2O + UDP-N-acetyl-alpha-D-galactosamine = 2 H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UMP


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Sus scrofa)


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Bos taurus)


name: 3-amino-2,4-dihydroxybenzoate + S-adenosyl-L-methionine => 3-amino-2-hydroxy-4-methoxybenzoate + H(+) + S-adenosyl-L-homocysteine


name: Interleukin-23 binds interleukin-23 receptor (Rattus norvegicus)


name: 6beta-hydroxyestradiol-17beta + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase]


name: ABCB4 transports PC from plasma membrane to extracellular region (Dictyostelium discoideum)


name: CoA + H(+) + N-(2-hydroxyhexacosanoyl)-sphinganine => 2-hydroxyhexacosanoyl-CoA + sphinganine


name: formaldehyde + H2O + N-methyl-L-proline + NAD(+) => H(+) + L-proline betaine + NADH + O2


name: ATP + erythritol = ADP + D-erythritol 4-phosphate + H(+)


name: "erythritol kinase (D-erythritol 4-phosphate-forming)"


name: eicosanoyl-CoA + sphinganine => CoA + H(+) + N-eicosanoylsphinganine


name: 7-deoxyloganetic aldehyde + O2 + reduced [NADPH--hemoprotein reductase] = 7-deoxyloganetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Co(I)-[methylated-thiol-specific corrinoid protein] + methanethiol <=> hydrogen sulfide + methyl-Co(III)-[methylated-thiol-specific corrinoid protein]


name: Phosphorylated MOB1A proteins associate with LATS proteins (Danio rerio)


name: VLDL translocates from SER lumen to extracellular region (Mus musculus)


name: ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A => ADP + H(+) + lipid A-core


name: acetylglucosamine-inositol is deacetylated by Mca (Mycobacterium tuberculosis)


name: 3-phenylpyruvate + H(+) + NADH => (R)-3-phenyllactate + NAD(+)


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Bos taurus)


name: 6-hydroxyhexanoate + NAD(+) <=> 6-oxohexanoate + H(+) + NADH


name: Trimming of peptides by IRAP in endocytic vesicles (Gallus gallus)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + phosphate => hexadecanoyl phosphate + sn-glycerol 3-phosphate


name: Beta-defensins 1, 4A and 103 bind CCR6 (Sus scrofa)


name: Activated FGFR1 phosphorylates FRS2 (Rattus norvegicus)


name: 3-sulfino-L-alanine + H(+) = CO2 + hypotaurine


name: ATP + CoA + hexanoate = AMP + diphosphate + hexanoyl-CoA


name: H(+) + N,N-dihydroxy-L-dihomomethionine <=> (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O


name: MLKL binds IP4, IP5 and IP6  (Bos taurus)


name: phloretin + UDP-alpha-D-glucose = H(+) + trilobatin + UDP


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Danio rerio)


name: OLR1 binds to oxidized LDL (Canis familiaris)


name: Nephrin trans-homophilic interaction (Rattus norvegicus)


name: ADRM1 binds 26S proteasome (Caenorhabditis elegans)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Xenopus tropicalis)


name: Aquaporins passively transport glycerol out of cells (Danio rerio)


name: Activation of EPACs by cAMP (Canis familiaris)


name: 2-hydroxycyclohexan-1-one + H(+) + NADPH + O2 => 6-hydroxyhexan-6-olide + H2O + NADP(+)


name: p-S MAPK6 phosphorylates NCOA3 (Gallus gallus)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Saccharomyces cerevisiae)


name: NTPDase1 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Canis familiaris)


name: CYP2S1 4-hydroxylates atRA (Rattus norvegicus)


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Bos taurus)


name: 9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone


name: POLD,POLE complete replication of damaged DNA after TLS (Homo sapiens)


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Rattus norvegicus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Canis familiaris)


name: NTPDase1 hydrolyzes nucleoside diphosphates (Bos taurus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: butan-1-ol + propanoyl-CoA <=> butyl propanoate + CoA


name: oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor


name: histone H3K56me2/H3K56me3 demethylase activity


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine


name: SUMOylation of TOPORS with SUMO1 (Sus scrofa)


name: (2E,6E,10E)-geranylgeraniol + ATP => (2E,6E,10E)-geranylgeranyl phosphate + ADP + H(+)


name: 2xTPK1:Mg2+ phosphorylates THMN (Rattus norvegicus)


name: (+)-corvol ether A + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: p-STAT1 dissociates from IL6ST:IL6ST (Gallus gallus)


name: a dicarboxylate(in) + N-benzoylglycine(out) => a dicarboxylate(out) + N-benzoylglycine(in)


name: H2O + N-(9Z-octadecenoyl)-taurine => (9Z)-octadecenoate + taurine


name: 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O <=> 2-oxopent-4-enoate + salicylate


name: L-tyrosine transmembrane transporter activity


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Mus musculus)


name: 2-oxoglutarate + gibberellin A1 + O2 = CO2 + gibberellin A8 + succinate


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Mus musculus)


name: a (Z)-N-(sulfonatooxy)alkenimidothioate = an alkenyl isothiocyanate + sulfate


name: PA is hydrolyzed to 1-acyl LPA by PLA2[15] (Drosophila melanogaster)


name: 2 (S)-methylmalonyl-CoA + 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH => C35-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)


name: 2 H(+) + H2O + N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase] => L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: formaldehyde + mycothiol => S-(hydroxymethyl)mycothiol


name: RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Canis familiaris)


name: dimethylallyl diphosphate + harmol => 6-(3-dimethylallyl)harmol + diphosphate


name: Ca impermeable AMPA receptor ligand binding (Gallus gallus)


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-methyl-5'-thioadenosine => L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Xenopus tropicalis)


name: (2R)-2-phosphoglycerate + H2O = (R)-glycerate + phosphate


name: H(+) + NADH + presqualene diphosphate = diphosphate + NAD(+) + squalene


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Drosophila melanogaster)


name: molybdate ion transmembrane transporter activity


name: Multiubiquitination of Nek2A (Sus scrofa)


name: arsenate + 3 H(+) + 2 reduced [azurin] => arsenite + H2O + 2 oxidized [azurin]


name: AcK-NFE2L2 binds the PDGFA gene (Homo sapiens)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Caenorhabditis elegans)


name: HLCS biotinylates ACACA:Mn2+ (Mus musculus)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Gallus gallus)


name: 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + sugiol => ferruginol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Saccharomyces cerevisiae)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Homo sapiens)


name: a diacylglycerol + an all-trans-retinyl ester => a triacylglycerol + all-trans-retinol


name: 2-amino-4-hydroxypteridine + O2 <=> 2-amino-4,7-dihydroxypteridine + chemical entity


name: an aliphatic alcohol + butanoate + H(+) => a butanoate ester + H2O


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + CDP-choline => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: NEK6/NEK7 phosphorylates NUP98 (Bos taurus)


name: Dephosphorylation of p107 (RBL1) by PP2A (Dictyostelium discoideum)


name: alpha-D-galactose 1-phosphate + H(+) + UTP => diphosphate + UDP-alpha-D-galactose


name: Release of Cytochrome c from mitochondria (Homo sapiens)


name: lanosterol + S-adenosyl-L-methionine => eburicol + H(+) + S-adenosyl-L-homocysteine


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Canis familiaris)


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Schizosaccharomyces pombe)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Drosophila melanogaster)


name: The p75NTR:NgR:MDGI binds RHOA-GDI (Danio rerio)


name: Interaction of Tie2 and Grb2 (Canis familiaris)


name: a 1,2-diacyl-sn-glycerol + H2O <=> a 2-acylglycerol + a fatty acid + H(+)


name: GPR161 is internalized (Rattus norvegicus)


name: CERK phosphorylates CERA to form C1P (Homo sapiens)


name: formaldehyde + H2O2 + L-lysine => H2O + N(6)-methyl-L-lysine + O2


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Drosophila melanogaster)


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Dictyostelium discoideum)


name: TPX2 promotes AURKA autophosphorylation (Mus musculus)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Rattus norvegicus)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Caenorhabditis elegans)


name: allulose 6-phosphate 3-epimerase activity


name: ABC-type iron-sulfur cluster transporter activity


name: Necl-1:Nectin-1 trans heterodimer interaction (Homo sapiens)


name: carbaryl + H(+) + H2O <=> 1-naphthol + CO2 + methylamine


name: Active LTK phosphorylates IRS1 (Homo sapiens)


name: 4-phospho-L-aspartate + ADP => ATP + L-aspartate


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Sus scrofa)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O => (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Homo sapiens)


name: loading of Serotonin in synaptic vesicles (Canis familiaris)


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Rattus norvegicus)


name: Formation of NR-NCOR Corepressor Complex (Xenopus tropicalis)


name: chloride(out) + L-proline(out) + 2 Na(+)(out) <=> chloride(in) + L-proline(in) + 2 Na(+)(in)


name: a mannosylinositol-1-phospho-N-acyl-sphingoid base + H2O => an N-acyl-sphingoid base + H(+) + mannosylinositol-1-phosphate


name: 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP(+)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Schizosaccharomyces pombe)


name: 2-hydroxy-2,3-dihydrogenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase]


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Homo sapiens)


name: Caspase mediated cleavage of alpha-II-Fodrin (Homo sapiens)


name: 1-tetradecanoylglycerol + H2O <=> glycerol + H(+) + tetradecanoate


name: RUNX1 binds SIN3A,(SIN3B) co-repressor (Canis familiaris)


name: MECP2 mutants R133C ,D121G, R133H and S134F do not bind 5hmC-DNA (Homo sapiens)


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Gallus gallus)


name: ATP + D-galacturonate => 1-phospho-alpha-D-galacturonate + ADP + H(+)


name: CDP-DAG is converted to PI by CDIPT (Xenopus tropicalis)


name: N-hydroxy-L-pentahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Elongation of pre-rRNA transcript (Mus musculus)


name: ESTG binds ESR1:chaperone complex (Sus scrofa)


name: adenosylcob(III)inamide phosphate + ADP + H(+) => adenosylcob(III)inamide + ATP


name: D-lactate dehydrogenase (quinone) activity


name: HDAC1:2-containing complex deacetylate histones (Drosophila melanogaster)


name: PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) (Saccharomyces cerevisiae)


name: H2O + N-acetyl-D-galactosamine + O2 <=> H(+) + H2O2 + N-acetyl-D-galactosaminate


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: chloroacetaldehyde + H2O + NAD(+) = chloroacetate + 2 H(+) + NADH


name: 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = (2R)-2-O-(alpha-D-mannosyl)-glycerate + phosphate


name: (2E,4E)-tetradecadienoyl-CoA + H(+) + NADPH <=> (3E)-tetradecenoyl-CoA + NADP(+)


name: Phosphorylation of VAV (Rattus norvegicus)


name: brain-derived neurotrophic factor receptor binding


name: HMOX1 dimer, HMOX2 cleave heme (Bos taurus)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Plasmodium falciparum)


name: UDP-alpha-D-galacturonate(in) + UMP(out) = UDP-alpha-D-galacturonate(out) + UMP(in)


name: Na(+)(out) + O-butanoyl-(R)-carnitine(out) <=> Na(+)(in) + O-butanoyl-(R)-carnitine(in)


name: G-protein coupled bile acid receptor binds lithocholic acid (Xenopus tropicalis)


name: Synthesis of GABA by GAD2 (Gallus gallus)


name: Importin-8 imports AGO2:miRNA into the nucleus (Sus scrofa)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Mus musculus)


name: CAMK1 binds calmodulin (Canis familiaris)


name: ADP-alpha-D-glucose + D-glucose = ADP + alpha,alpha-trehalose + H(+)


name: NDUF subunits bind to form the IP subcomplex (Homo sapiens)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Drosophila melanogaster)


name: Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Rattus norvegicus)


name: D-glucose + DIBOA => DIBOA beta-D-glucoside + H2O


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA


name: LARG activation by G alpha 12/13 (Sus scrofa)


name: Interaction of E3 with substrate and E2-Ub complex (Xenopus tropicalis)


name: metal ion transmembrane transporter activity


name: O2 + prostaglandin E1 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy prostaglandin E1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Mus musculus)


name: 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 = H(+) + 2 H2O + 2 L-citrulline + NAD(+) + 2 nitric oxide


name: Proteasome degrades ubiquitinated NICD4 (Homo sapiens)


name: Hemoglobin:Haptoglobin:CD163 is endocytosed (Bos taurus)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Dictyostelium discoideum)


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Bos taurus)


name: α2-agonists bind ADRA2A,B,C (Homo sapiens)


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Rattus norvegicus)


name: D-maltobiono-1,5-lactone + H2O2 => D-maltose + O2


name: a long-chain fatty aldehyde + holo-[ACP] + NAD(+) <=> a long-chain fatty acyl-[ACP] + H(+) + NADH


name: Formation of the MCC complex (Caenorhabditis elegans)


name: MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: an alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate <=> an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: 2-methyl-cis-aconitate + H2O => (2S,3S)-2-methylcitrate


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine


name: DEGS2 oxygenates dihydroceramide (Dictyostelium discoideum)


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Rattus norvegicus)


name: PRKG is activated by binding to high levels of cGMP in the absence of WNT signaling (Homo sapiens)


name: KDM5A-D demethylate Me2K5-histone H3 (Schizosaccharomyces pombe)


name: Activation of proMMP7 by MMP3 (Gallus gallus)


name: oxalate(in) + sulfate(out) <=> oxalate(out) + sulfate(in)


name: Initial resection of double-strand break ends (Gallus gallus)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Danio rerio)


name: a 5'-end triphospho-guanosine in mRNA + H2O <=> a 5'-end diphospho-guanosine in mRNA + H(+) + phosphate


name: H2O + N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein] = 3-deoxyglucosone + L-lysyl-[protein] + phosphate


name: a 1,2-diacyl-sn-glycerol + an acyl-CoA <=> a triacyl-sn-glycerol + CoA


name: cysteine-type endopeptidase activator activity


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Canis familiaris)


name: SMURF1/2 dissociates from ub-PTCH1 (Drosophila melanogaster)


name: 2-oxoglutarate + L-histidyl-[ribosomal protein uL15] + O2 <=> (3S)-3-hydroxy-L-histidyl-[ribosomal protein uL15] + CO2 + succinate


name: FADH2-C4alpha-hydroperoxide + NADP(+) => FAD + 2 H(+) + NADPH + O2


name: an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-xylose = an anthocyanidin 3-O-beta-D-sambubioside + 2 H(+) + UDP


name: SALMs 1-3 bind to PSD-95 family members (Rattus norvegicus)


name: Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Dictyostelium discoideum)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] <=> a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester + apo--[retinol-binding protein]


name: (E)-feruloyl-CoA + H(+) + S-adenosyl-L-homocysteine => (E)-caffeoyl-CoA + S-adenosyl-L-methionine


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Caenorhabditis elegans)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Bos taurus)


name: Expression of Acetyl CoA Carboxylase 2 (ACACB, ACC2) (Homo sapiens)


name: [sulfur carrier]-SH + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + S-adenosyl-L-methionine = [sulfur carrier]-H + H(+) + L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose <=> L-glutamate + UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose


name: 4-coumaroyl-CoA + 2 H(+) + 3 malonyl-CoA = 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoA


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)


name: adenosine 5'-phosphosulfate + diphosphate => ATP + H(+) + sulfate


name: (+)-sesamin monocatechol + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) <=> (+)-sesamin dicatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n)


name: H(+) + NADPH + O2 + phenol = catechol + H2O + NADP(+)


name: TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 (Homo sapiens)


name: 3 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) => 3 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3)


name: NTPDase1 hydrolyzes nucleoside triphosphates (Rattus norvegicus)


name: butanal + CoA + NADP(+) => butanoyl-CoA + H(+) + NADPH


name: AMP + diphosphate + IC-asc-C9-CoA => ATP + CoA + IC-asc-C9


name: SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Rattus norvegicus)


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Rattus norvegicus)


name: isoorientin + O2 <=> 3''-dehydroisoorientin + H2O2


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Homo sapiens)


name: CO2 + hypotaurine => 3-sulfino-L-alanine + H(+)


name: DOCKs bind to RhoGEFs (Saccharomyces cerevisiae)


name: ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Sus scrofa)


name: a 3'-end 2'-deoxyribonucleotidyl-deoxyribonucleotide-DNA + H2O = a 2'-deoxyribonucleoside 5'-phosphate + a 3'-end 2'-deoxyribonucleotide-DNA + H(+)


name: ADP-D-glycero-beta-D-manno-heptose + L-seryl-[protein] => ADP + H(+) + O-(D-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein]


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Plasmodium falciparum)


name: MAPK4,6 translocate to the cytoplasm (Canis familiaris)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Rattus norvegicus)


name: 3,4-dihydroxyphenylacetate + CoA + H(+) => 3,4-dihydroxyphenylacetyl-CoA + H2O


name: extracellularly ATP-gated monoatomic cation channel activity


name: P2X7 mediates loss of intracellular K+ (Homo sapiens)


name: L1 linked to actin cytoskeleton by ankyrin (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR4 (Canis familiaris)


name: PRKCB gene expression is stimulated by RUNX1 (Homo sapiens)


name: CDC42:GTP binds PAK2 (Caenorhabditis elegans)


name: glutamate uptake by astrocytes (Caenorhabditis elegans)


name: RUNX1 binds the SWI/SNF complex (Homo sapiens)


name: Na+-driven Cl-/HCO3- exchanger transport (Drosophila melanogaster)


name: Multiphospho-CERT1-2 binds PPM1L, VAPA/B (Bos taurus)


name: ADP-alpha-D-ribose 1''-phosphate + H2O <=> ADP-D-ribose + phosphate


name: Budding of vesicle with the HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum into the cytosol (Homo sapiens)


name: L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP


name: RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)


name: Activated FGFR1 phosphorylates SHC1 (Caenorhabditis elegans)


name: Polyubiquitinated NRIF binds to p62 (Sequestosome) (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: acetyl-CoA + hydrogen sulfide <=> CoA + thioacetate


name: ATP + hydrogencarbonate + NH4(+) => ADP + carbamoyl phosphate + H(+) + H2O


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Gallus gallus)


name: (20S)-protopanaxadiol + O2 + reduced [NADPH--hemoprotein reductase] = (20S)-protopanaxatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Homo sapiens)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Homo sapiens)


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: 2-dehydro-3-deoxy-6-phospho-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate


name: 4 PBGs bind to form HMB (Schizosaccharomyces pombe)


name: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate


name: WWOX binds TFAP2C (Caenorhabditis elegans)


name: H(+) + NADP(+) + 2 reduced [adrenodoxin] = NADPH + 2 oxidized [adrenodoxin]


name: Dephosphorylation of p107 (RBL1) by PP2A (Sus scrofa)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex (Homo sapiens)


name: ECHS1 hydrates methacrylyl-CoA (Bos taurus)


name: ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA (Dictyostelium discoideum)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Caenorhabditis elegans)


name: 15,16-epoxydolabrene + O2 + reduced [NADPH--hemoprotein reductase] => 3beta-hydroxy-15,16-epoxydolabrene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetoacetate + N,N,N-trimethylglycyl-CoA => 3-dehydrocarnitine + acetyl-CoA


name: Self-ubiquitination of RNF41 (Drosophila melanogaster)


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Schizosaccharomyces pombe)


name: RDH10,11 oxidise 11cROL to 11cRAL (Xenopus tropicalis)


name: H2O + S-(hercyn-2-yl)-L-cysteine S-oxide => 2-sulfenohercynine + NH4(+) + pyruvate


name: D-mannose 6-phosphate + H2O => D-mannose + phosphate


name: 2,5-dioxopiperazine + H2O => glycylglycine


name: Oxidative damage to the AP site (Dictyostelium discoideum)


name: XIAP dissociates from ub-TLE (Xenopus tropicalis)


name: 2-(9Z-octadecenoyl)-glycerol + eicosanoyl-CoA <=> 1-eicosanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: POLB-mediated DNA strand displacement synthesis (Sus scrofa)


name: 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 4 H(+) + molybdopterin => 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + cyclic pyranopterin phosphate + H2O


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Homo sapiens)


name: "Transferring alkyl or aryl groups, other than methyl groups"


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Drosophila melanogaster)


name: MIB2 ubiquitinates CFLAR  (Rattus norvegicus)


name: ATP + N-(hexanoyl)sphing-4-enine <=> ADP + H(+) + N-hexanoylsphing-4-enine 1-phosphate


name: Monoubiquitinated PTEN translocates to the nucleus (Drosophila melanogaster)


name: H2O + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] => ADP-D-ribose + L-arginyl-[protein]


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine = 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 4 H(+) + 3 L-methionine


name: "anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase"


name: FUOM isomerises alpha-Fuc to beta-Fuc (Canis familiaris)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Plasmodium falciparum)


name: FBXW7 WD mutants do not bind NICD1 (Homo sapiens)


name: (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] => (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: 2 ATP + 2 L-glutamate + N-acetyl-L-aspartate => 2 ADP + 2 H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate + 2 phosphate


name: dehydroepiandrosterone 3-sulfate + O2 + reduced [NADPH--hemoprotein reductase] => 16alpha-hydroxydehydroepiandrosterone 3-sulfate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)


name: PARG dePARylates PARP1,PARP2 (Mus musculus)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Mus musculus)


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Sus scrofa)


name: Interaction of Tie2 and Shp2 (Mus musculus)


name: 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2 => 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H(+)


name: (20S)-protopanaxatriol + UDP-alpha-D-glucose <=> (20S)-ginsenoside F1 + H(+) + UDP


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+) => 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADPH


name: mRNP complex dissociates from cytosolic face of NPC (Homo sapiens)


name: a carboxylate + ATP + H(+) + NADPH = AMP + an aldehyde + diphosphate + NADP(+)


name: glucoraphanin + H2O <=> (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = (9Z)-octadecenoate + (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + H(+)


name: L-lysyl-[protein] + propanoyl-CoA => CoA + H(+) + N(6)-propanoyl-L-lysyl-[protein]


name: EVL:PPL heterodimer binds the inner surface of the plasma membrane (Xenopus tropicalis)


name: CTP + UTP => cyclic CMP-UMP + 2 diphosphate


name: ALOX5 binds ALOX5 inhibitors (Xenopus tropicalis)


name: MLKL binds PDCD6IP and SDCBP (Homo sapiens)


name: H(+) + S-adenosyl-L-homocysteine + ubiquinol-7 => 3-demethylubiquinol-7 + S-adenosyl-L-methionine


name: CXXC1 and WDR82 bind SET1A complex (Dictyostelium discoideum)


name: dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Danio rerio)


name: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA <=> 10-deacetylbaccatin III + CoA


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Caenorhabditis elegans)


name: LDLR is bound by DAB2 and ARH (Mus musculus)


name: (+)-copalyl diphosphate = diphosphate + isopimara-8(14),15-diene


name: ATP + glycerol 2-phosphate(out) + H2O => ADP + glycerol 2-phosphate(in) + H(+) + phosphate


name: glyoxylate + urea => (S)-ureidoglycolate


name: voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


name: a (3R)-hydroxyacyl-[ACP] => a (2E)-enoyl-[ACP] + H2O


name: BTN3A1 binds prenylated phosphoantigens (Homo sapiens)


name: RSF complex binds the centromere (Homo sapiens)


name: ATP + geranoyl-CoA + hydrogencarbonate <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + H(+) + phosphate


name: ATP + 4 H(+)(in) + H2O <=> ADP + 5 H(+)(out) + phosphate


name: 11-cis-retinol + tetradecanoyl-CoA => 11-cis-retinyl tetradecanoate + CoA


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Danio rerio)


name: PRDX1 overoxidizes (Drosophila melanogaster)


name: Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Bos taurus)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Drosophila melanogaster)


name: eNOS synthesizes NO (Schizosaccharomyces pombe)


name: (R)-carnitine(out) + ATP + H2O = (R)-carnitine(in) + ADP + H(+) + phosphate


name: acetoacetate + acetyl-CoA <=> acetate + acetoacetyl-CoA


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Rattus norvegicus)


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Gallus gallus)


name: lysophosphatidic acid acyltransferase activity


name: Activation of RAS by p-KIT bound SOS1 (Rattus norvegicus)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Mus musculus)


name: Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Mus musculus)


name: (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate + ATP + CoA <=> (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate


name: cadaverine + H2O + O2 = 5-aminopentanal + H2O2 + NH4(+)


name: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + enolpyruvoyl-2-diphospho-5'-guanosine <=> dehydro coenzyme F420-0 + GMP + H(+)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Gallus gallus)


name: 2,6-dichlorobenzoquinone + chloride + FAD + H(+) + H2O => 2,4,6-trichlorophenol + FADH2 + O2


name: N,N'-diacetylchitobiose + phosphate => N-acetyl-alpha-D-glucosamine 1-phosphate + N-acetyl-D-glucosamine


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Gallus gallus)


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Xenopus tropicalis)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Xenopus tropicalis)


name: p-Y-STATs dissociate (Rattus norvegicus)


name: CXXC1 and WDR82 bind SET1B complex (Saccharomyces cerevisiae)


name: cis-aconitate + H2O <=> D-threo-isocitrate


name: a 3beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid + H(+) + NADH


name: Packaging of HIV virion on the host cell plasma membrane (Homo sapiens)


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-jasmololone = CoA + jasmolin II


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Homo sapiens)


name: butanoate(out) + dehydroepiandrosterone 3-sulfate(in) => butanoate(in) + dehydroepiandrosterone 3-sulfate(out)


name: (2E,6E)-farnesyl diphosphate + H2O => diphosphate + presilphiperfolan-8beta-ol


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Drosophila melanogaster)


name: ST3GAL2,3 transfer Neu5Ac to gangliosides (Rattus norvegicus)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH => (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: H(+) + S-adenosyl-L-homocysteine + vanillate => 3,4-dihydroxybenzoate + S-adenosyl-L-methionine


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Canis familiaris)


name: Exocytosis of ficolin-rich granule lumen proteins (Danio rerio)


name: Formation of the CTF18 complex (Gallus gallus)


name: a pyrimidine ribonucleoside 5'-phosphate + H2O => a pyrimidine nucleobase + D-ribose 5-phosphate


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O => a 5'-end phospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-GDP


name: 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + H2O2 <=> 3,4-dimethoxybenzaldehyde + glycolaldehyde + guaiacol + H2O


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: phosphate + streptomycin => H2O + streptomycin 6-phosphate