name: DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine


name: AMP + H2O => adenosine + orthophosphate [NT5C1B] (Sus scrofa)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Gallus gallus)


name: acetophenone + 2 ATP + H2O + hydrogencarbonate = 3-oxo-3-phenylpropanoate + 2 ADP + 2 H(+) + 2 phosphate


name: RHOB GAPs stimulate RHOB GTPase activity (Saccharomyces cerevisiae)


name: chloride(out) + creatine(out) + 2 Na(+)(out) => chloride(in) + creatine(in) + 2 Na(+)(in)


name: acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative => an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O


name: (9Z)-octadecenoyl-CoA + H2O <=> (9Z)-octadecenoate + CoA + H(+)


name: alpha-maltose 6'-phosphate + H2O => D-glucose + D-glucose 6-phosphate


name: H2O2 + NAD(+) => 1,2-dihydro-beta-NAD + H(+) + O2


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Sus scrofa)


name: acetyl-CoA + AH2 + H(+) + 3 malonyl-CoA + 2 S-adenosyl-L-methionine => A + clavatol + 3 CO2 + 4 CoA + H2O + 2 S-adenosyl-L-homocysteine


name: PE is hydrolyzed to 2-acyl LPE by PLA2G4C (Schizosaccharomyces pombe)


name: Tyrosine is hydroxylated to dopa (Sus scrofa)


name: MTMR8 binds MTMR9 (Dictyostelium discoideum)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Gallus gallus)


name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes (Homo sapiens)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Canis familiaris)


name: trans-2-enoyl-CoA reductase (NADH) activity


name: NCEH1 hydrolyzes cholesterol esters (Mus musculus)


name: LDLR:LDL complex => LDLR + LDL (Sus scrofa)


name: 2 a plastoquinone + 2 H2O + 4 hnu <=> 2 a plastoquinol + O2


name: (+)-artemisinic alcohol + NAD(+) <=> (+)-artemisinic aldehyde + H(+) + NADH


name: Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Xenopus tropicalis)


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Drosophila melanogaster)


name: H2O2 + tetradecanoate = (2R)-hydroxytetradecanoate + H2O


name: MAP2K1 binds MAPK3 (Saccharomyces cerevisiae)


name: (+)-6-exo-hydroxycamphor + H2O + NADP(+) => (1R,4R)-camphor + H(+) + NADPH + O2


name: 3-aminocoumarate + ATP + H(+) + nitrite => 3-diazocoumarate + AMP + diphosphate + H2O


name: 2-(acylamino)ethyl fatty acid + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylethanolamine


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose => alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP + H(+)


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Xenopus tropicalis)


name: Transfer of NEDD8 to AcM-UBE2M (Bos taurus)


name: GLI3R translocates to the nucleus (Drosophila melanogaster)


name: glutathione + prostaglandin A2 <=> prostaglandin A2-S-(S)-glutathione


name: a triacyl-sn-glycerol + H2O => a 1,3-diacyl-sn-glycerol + a fatty acid + H(+)


name: P4HB mediates disulfide bond formation in Proinsulin (Bos taurus)


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Danio rerio)


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Danio rerio)


name: Necl-1:Necl-2 trans heterodimer interaction (Homo sapiens)


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Xenopus tropicalis)


name: PLG(20-810) binds anti-fibrinolytics (Sus scrofa)


name: H2O + L-seryl-tRNA(Ser) => L-serine + tRNA(Ser)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR3 (Canis familiaris)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Sus scrofa)


name: (3R)-3-{[carboxy(hydroxy)methyl]amino}butanoate + 2-oxoglutarate + O2 = (3R)-3-isocyanylbutanoate + 2 CO2 + 2 H2O + succinate


name: p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)


name: H(+) + NADPH + 2 phytyl diphosphate = (14E,18E)-lycopadiene + 2 diphosphate + NADP(+)


name: LDHAL6B reduces PYR to LACT (Canis familiaris)


name: Importin-8 imports AGO2:miRNA into the nucleus (Homo sapiens)


name: PAN2-PAN3 complex partially deadenylates mRNA (Sus scrofa)


name: androst-5-en-3beta,7alpha,17beta-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => androst-5-en-3beta,17beta-diol + O2 + reduced [NADPH--hemoprotein reductase]


name: Transfer of LPS onto TLR4 (Homo sapiens)


name: CALCR binds gepants (Caenorhabditis elegans)


name: ERK5 translocates to the nucleus (Rattus norvegicus)


name: Phosphorylation of Cyclin A:Cdk2 at Tyr 15 (Drosophila melanogaster)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Saccharomyces cerevisiae)


name: dTDP-beta-L-rhamnose + N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol <=> alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + dTDP + H(+)


name: a [peptide](out) + ATP + H2O = a [peptide](in) + ADP + H(+) + phosphate


name: Cargo Recognition And Sorting (Homo sapiens)


name: 3alpha-hydroxy-5alpha-pregnan-20-one + NAD(+) => 5alpha-pregnane-3,20-dione + H(+) + NADH


name: (8Z,11Z,14Z)-eicosatrienoate + O2 <=> (8R)-hydroperoxy-(9E,11Z,14Z)-eicosatrienoate


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Homo sapiens)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Canis familiaris)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: EXA4 is converted to EXC4 by LTC4S (Dictyostelium discoideum)


name: SFTPD binds with itself to form SFTPD 12mer (Sus scrofa)


name: acetyl-CoA + N-terminal L-prolyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-prolyl-[protein]


name: H(+) + NADPH + UDP-4-dehydro-beta-L-rhamnose = NADP(+) + UDP-beta-L-rhamnose


name: Arachidonic acid is oxidised to PGG2 by PTGS2 (Mus musculus)


name: p-S256-Aquaporin-2 passively transports water into cell (Mus musculus)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Schizosaccharomyces pombe)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Schizosaccharomyces pombe)


name: TMEM55B translocates to the nucleus (Sus scrofa)


name: (S)-5-carboxymethyl-tetronate + o-quinone methide => H(+) + penilactone D


name: Elongating transcript encounters a lesion in the template (Mus musculus)


name: FGFR1c binds to FGF (Caenorhabditis elegans)


name: LONP1 binds mitochondrial inner membrane proteins (Saccharomyces cerevisiae)


name: CBL ubiquitinates PI3K (Xenopus tropicalis)


name: Binding of A1CF to stem-looped RNA (Xenopus tropicalis)


name: GUK1 phosphorylates 6TGMP to 6TGDP (Drosophila melanogaster)


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Mus musculus)


name: (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine => 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoserine + CoA


name: 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O => (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + catechol + H(+)


name: hydrogen sulfide + O-succinyl-L-serine = L-cysteine + succinate


name: all-trans-retinyl hexadecanoate + CoA => all-trans-retinol + hexadecanoyl-CoA


name: H2O + plasmodiophorol B => plasmodiophorol C


name: NOTCH3 binds activated EGFR (Mus musculus)


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Rattus norvegicus)


name: Regeneration of eEF1A:GTP by eEF1B activity (Rattus norvegicus)


name: L-arginine(in) + L-phenylalanine(out) => L-arginine(out) + L-phenylalanine(in)


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O <=> 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)


name: SUMOylation of RARA with SUMO2 (Rattus norvegicus)


name: SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Caenorhabditis elegans)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Rattus norvegicus)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Caenorhabditis elegans)


name: Estrogen receptor binds IGF1R and SHC1 in response to estrogen (Gallus gallus)


name: "Catalysing the translocation of inorganic anions and their chelates"


name: alpha-secretase cleaves the p75NTR extracellular domain (Gallus gallus)


name: Receptor CCR10 binds CCL27 and 28 ligands (Canis familiaris)


name: Sequestration of BAD protein by 14-3-3 (Mus musculus)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Drosophila melanogaster)


name: 7-oxoheptanoyl-[ACP] + a fatty aldehyde + H(+) + 2 H2O + oxidized [flavodoxin] => a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin]


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Mus musculus)


name: an (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (2R)-2-O-(alpha-D-mannosyl)-glycerate(out) + N(pros)-phospho-L-histidyl-[protein] = (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate(in) + L-histidyl-[protein]


name: (S)-lactate + 2 Fe(III)-[cytochrome c] => 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Mus musculus)


name: dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 3 H2O + 2 NADP(+) => dTDP-beta-L-evernosamine + H(+) + 2 NADPH + 2 O2


name: (2S)-hydroxybutanoate + NAD(+) = 2-oxobutanoate + H(+) + NADH


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol <=> a 1,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: CARKD dehydrates S-NAD(P)HX to NADPH (Homo sapiens)


name: CBL monoubiquitinates activated MET (Sus scrofa)


name: SFTPB binds itself (Dictyostelium discoideum)


name: Interaction of PECAM-1 and SHP-1 (Canis familiaris)


name: LDH tetramer oxidises LACT to PYR (Bos taurus)


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Canis familiaris)


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Canis familiaris)


name: CTP + di-trans,poly-cis-dolichol <=> a dolichyl phosphate + CDP + H(+)


name: 2 Fe(II)-[cytochrome c] + H(+) + nitroxyl + O2 => 2 Fe(III)-[cytochrome c] + H2O + nitrite


name: NFE2L2-dependent SRXN1 gene expression (Homo sapiens)


name: CYP2S1 4-hydroxylates atRA (Caenorhabditis elegans)


name: Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)


name: H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate


name: "oxaloacetate decarboxylase (Na(+) extruding)"


name: SENP1,2,5 proteolytically process SUMO1 (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate <=> (1R,4S)-camphene + diphosphate


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Rattus norvegicus)


name: ATP + CoA + octanedioate = AMP + diphosphate + octanedioyl-CoA


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Canis familiaris)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Sus scrofa)


name: (E)-feruloyl-CoA + (E)-feruloylacetyl-CoA + H2O => CO2 + 2 CoA + curcumin


name: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate => 4-carboxy-2-hydroxy-cis,cis-muconate + H2O


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Canis familiaris)


name: H2O + lovastatin => (S)-2-methylbutanoate + H(+) + monacolin J


name: H(+) + NADH + NH4(+) + oxaloacetate => H2O + L-aspartate + NAD(+)


name: PI3K synthesizes PIP3 downstream of ALK (Bos taurus)


name: formaldehyde + mycothiol = S-(hydroxymethyl)mycothiol


name: BLVRA:Zn2+, BLVRB reduce BV to BIL (Sus scrofa)


name: Deacetylation of cleaved cohesin (Bos taurus)


name: apoTF:TFRC dimer translocates from endosome membrane to plasma membrane (Bos taurus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Gallus gallus)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Dictyostelium discoideum)


name: MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix (Gallus gallus)


name: Formation of hydroxylysyl-pyridinoline cross-links (Rattus norvegicus)


name: ADO oxidises 2AET to HTAU (Drosophila melanogaster)


name: (9Z)-octadecenoate + H(+) + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine => H2O + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Canis familiaris)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Gallus gallus)


name: Activated ATM phosphorylates ABL1 (Canis familiaris)


name: STAT1,STAT3,STAT6 bind IL13:IL13R type II (Sus scrofa)


name: [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B <=> (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B + H2O


name: Formation of RAD52 heptameric ring structure complexes (Gallus gallus)


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)


name: 2-methoxy-6-(all-trans-hexaprenyl)phenol + H(+) + NADPH + O2 = 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + H2O + NADP(+)


name: tRNA-specific adenosine deaminase activity


name: OCT3 mediates renal uptake of organic cations (Canis familiaris)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24R)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SUMOylation of ING2 with SUMO1 (Bos taurus)


name: LIG1 binds POLB at long-patch BER site (Sus scrofa)


name: TNF-mediated dimerization of procaspase-8 (Bos taurus)


name: Netrin-1 induced DCC clustering (Danio rerio)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: ATP + D-tyrosine + tRNA(Tyr) <=> AMP + D-tyrosyl-tRNA(Tyr) + diphosphate + H(+)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Xenopus tropicalis)


name: 2-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: apolipoprotein(a) + LDL => Lp(a) (Homo sapiens)


name: H2O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one


name: IL24 binds IL20RA:JAK1:IL20RB (Gallus gallus)


name: H2O + luteolin 7-O-beta-D-glucoside <=> beta-D-glucose + luteolin


name: MeSeO2H is reduced to MeSeOH by TXNRD1 (Caenorhabditis elegans)


name: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate => 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Rattus norvegicus)


name: (n-1) H2O + RNA(n) <=> n a ribonucleoside 5'-phosphate + n H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O <=> 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)


name: 2-phenylethanol + benzoyl-CoA = CoA + phenethyl benzoate


name: PTGFR binds PTGFR agonists (Xenopus tropicalis)


name: a fatty acid + H(+) + long chain acyl-3-O-beta-D-galactosyl-sn-glycerol => H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol


name: ATP + L-glutamate + tyramine = ADP + gamma-L-glutamyltyramine + H(+) + phosphate


name: ribose phosphate diphosphokinase activity


name: phosphate + thiamine => H2O + thiamine phosphate


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Xenopus tropicalis)


name: 5-hydroxy-2,4-dioxopentanoate + H(+) + NADH => 2-dehydro-3-deoxy-D-arabinonate + NAD(+)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Rattus norvegicus)


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Homo sapiens)


name: FDPS dimer transfers IPPP to DMAPP (Dictyostelium discoideum)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)


name: Group 3 - Selective Cl- transport (Caenorhabditis elegans)


name: transmembrane histidine kinase cytokinin receptor activity


name: 5-dehydro-2-deoxy-D-gluconate + ATP = 6-phospho-5-dehydro-2-deoxy-D-gluconate + ADP + H(+)


name: CCNK binds CDK13 (Drosophila melanogaster)


name: CMP-N-acetyl-beta-neuraminate + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] <=> 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+)


name: diphosphate + P(1),P(4)-bis(5'-adenosyl) tetraphosphate => 2 ATP + H(+)


name: MMP14 (MT1-MMP) binds TIMP2 (Drosophila melanogaster)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: diphosphate + gamma-curcumene => (2E,6E)-farnesyl diphosphate


name: Glucagon-like receptor 2 binds GLP2 (Xenopus tropicalis)


name: an S-alkyl-L-cysteine S-oxide <=> 2-aminoprop-2-enoate + an S-alkyl sulfenate


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Xenopus tropicalis)


name: a ganglioside GM1 (d18:1(4E)) + H2O <=> a ganglioside GM2 (d18:1(4E)) + D-galactose


name: 3-O-(alpha-L-fucosyl)-L-threonyl-[protein] + UDP-alpha-D-glucose = 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[protein] + H(+) + UDP


name: H(+) + hyodeoxycholate 6-O-(beta-D-glucuronate) + UDP => hyodeoxycholate + UDP-alpha-D-glucuronate


name: MTMR4 dephosphorylates SMAD2/3 (Sus scrofa)


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Saccharomyces cerevisiae)


name: MeSebGalNac is hydrolysed to MeSeH and bGalNac (Homo sapiens)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Homo sapiens)


name: Dimerization of p-S446-IRF5 (Sus scrofa)


name: 5'-triphosphoadenylyl-(2'->5')-adenosine + H2O => AMP + ATP + H(+)


name: Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs (Homo sapiens)


name: ATP + L-cysteine + L-glutamate <=> ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate


name: mycothiol-dependent formaldehyde dehydrogenase activity


name: Calcium Influx through Voltage-gated Calcium Channels (Drosophila melanogaster)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Mus musculus)


name: benzoyl-CoA + H2O + oxidized 2[4Fe-4S]-[ferredoxin] <=> 4-hydroxybenzoyl-CoA + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Bos taurus)


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Homo sapiens)


name: Endorepellin binds alpha2beta1 integrin (Drosophila melanogaster)


name: (4R)-hydroxysphinganine + a fatty acid => an N-acyl-(4R)-4-hydroxysphinganine + H2O


name: GBF1 stimulates nucleotide exchange on ARF4 (Homo sapiens)


name: [HPr protein]-O-phospho-L-serine + H(+) + phosphate <=> [HPr protein]-L-serine + diphosphate


name: NEUROG3-dependent synthesis of NKX2-2 (Homo sapiens)


name: CFTR transports Cl- from cytosol to extracellular region (Gallus gallus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Schizosaccharomyces pombe)


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-dGTP => dGTP + glycolate + H(+)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Sus scrofa)


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O = 1-dodecanoyl-sn-glycerol + H(+) + phosphocholine


name: ANKLE2 is deacetylated by SIRT2 (Bos taurus)


name: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: H(+) + prunetin-C(8)-beta-D-glucuronide + UDP => prunetin + UDP-alpha-D-glucuronate


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + A + 2 H2O => (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + AH2 + O2


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Rattus norvegicus)


name: 1-(9Z,12Z-octadecadienoyl)-2-acyl-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ATP + D-fructose <=> ADP + D-fructose 6-phosphate + H(+)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Bos taurus)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) + H2O = 1-O-alkyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + phosphate


name: ARL1:GTP binds ARFIP2 (Canis familiaris)


name: TTPA binds alpha-TOH (Rattus norvegicus)


name: H(+) + H2O + N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase] => N-hydroxy-L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Gallus gallus)


name: ADRM1:26S proteaseome binds USP14 (Plasmodium falciparum)


name: Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation<br> (Drosophila melanogaster)


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Saccharomyces cerevisiae)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Canis familiaris)


name: (9Z)-tetradecenoate + ATP + CoA = (9Z)-tetradecenoyl-CoA + AMP + diphosphate


name: TIFA oligomerization (Xenopus tropicalis)


name: dehydroepiandrosterone 3-sulfate(in) + pentanoate(out) = dehydroepiandrosterone 3-sulfate(out) + pentanoate(in)


name: a dolichyl beta-D-mannosyl phosphate + H2O = a dolichyl phosphate + D-mannose + H(+)


name: PGRMC2:Hemes dissociates (Dictyostelium discoideum)


name: MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Homo sapiens)


name: TCR binds microbial lipid-based antigen via CD1 (Mus musculus)


name: Expression of POU3F1 in anterior neural plate (Homo sapiens)


name: TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Homo sapiens)


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2B (GRIN2B) (Homo sapiens)


name: 2 a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Dictyostelium discoideum)


name: DNA polymerase epsilon binds at the origin (Xenopus tropicalis)


name: p-S446-IRF5 dimer translocates to the nucleus (Bos taurus)


name: Formation of hydroxyallysine by LOX (Danio rerio)


name: (9Z,12Z)-octadecadienoyl-CoA + 2-(9Z-octadecenoyl)-glycerol <=> 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: UCKL1 phosphorylates urindine, cytidine (Schizosaccharomyces pombe)


name: (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMNH2 + O2 = benzaldehyde + FMN + H(+) + H2O + N-acetyl-S-hydroxy-L-cysteine


name: H2O + N(6)-dodecanoyl-L-lysyl-[protein] + NAD(+) = 2''-O-dodecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Xenopus tropicalis)


name: Digestion of triacylglycerols by extracellular PTL:colipase (Rattus norvegicus)


name: caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity


name: 5alpha-pregnane-3,20-dione + H(+) + NADH => 3alpha-hydroxy-5alpha-pregnan-20-one + NAD(+)


name: (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: H(+)(out) + thiamine(in) => H(+)(in) + thiamine(out)


name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 => 8-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate


name: SRC-1 phosphorylates PTK2-beta (Sus scrofa)


name: ADGRG heterodimer translocates to plasma membrane (Homo sapiens)


name: ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1) (Homo sapiens)


name: Activation of TAK1-TAB2 complex (Rattus norvegicus)


name: (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H2O <=> 4-hydroxy-2-oxohexanoate


name: a globoside Gb3Cer (d18:1(4E)) + H2O = a fatty acid + a lysoGb3(d18:1(4E))


name: Homodimerization of VEGF proteins (Rattus norvegicus)


name: TRAF6 oligomer autoubiquitinates (Mus musculus)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Danio rerio)


name: ATP + dihydrostreptomycin 6-phosphate <=> ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + H(+)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Drosophila melanogaster)


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Sus scrofa)


name: 3,8-divinyl chlorophyllide a + ATP + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin] => ADP + bacteriochlorophyllide g + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate


name: (10S)-hydroxy-(6Z,12Z,15Z)-octadecatrienoate => (6Z,9Z,12Z,15Z)-octadecatetraenoate + H2O


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Caenorhabditis elegans)


name: 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2


name: chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols (Rattus norvegicus)


name: (R)-mevalonate + CoA + 2 NADP(+) => (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH


name: glutathione + H2O => L-cysteinylglycine + L-glutamate


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Rattus norvegicus)


name: Caspase-mediated cleavage of Lamin A (Sus scrofa)


name: OCT3 mediates renal uptake of organic cations (Gallus gallus)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Homo sapiens)


name: PDGF binds to extracellular matrix proteins (Sus scrofa)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Mus musculus)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Saccharomyces cerevisiae)


name: a dolichyl phosphate + H2O <=> di-trans,poly-cis-dolichol + phosphate


name: CDK1 phosphorylates RUNX2 (Canis familiaris)


name: (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA <=> (E)-2-benzylidenesuccinyl-CoA + H2O


name: dodecanal + H2O + O2 <=> dodecanoate + H(+) + H2O2


name: ATP + carbamoyl phosphate + H2O <=> carbamoyl adenylate + diphosphate + phosphate


name: H2O + neurotensin = L-leucine + neurotensin-(1-12)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Caenorhabditis elegans)


name: factor IXa associates with cell membrane (Homo sapiens)


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Homo sapiens)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Canis familiaris)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Mus musculus)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Mus musculus)


name: Activated JNKs phosphorylate c-JUN (Caenorhabditis elegans)


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Mus musculus)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)


name: SEMA4D interacts with Plexin-B1:Met (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = H(+) + hexadecanoate + hexadecanoyl-sn-glycero-3-phosphocholine


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Gallus gallus)


name: EET(1) is hydrolysed to DHET(1) by EPHX2 (Bos taurus)


name: ADP + D-cystine(in) + H(+) + phosphate => ATP + D-cystine(out) + H2O


name: glycolate + NAD(+) => glyoxylate + H(+) + NADH


name: H2O + N-(4-aminobenzoyl)-L-glutamate <=> 4-aminobenzoate + L-glutamate


name: 6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O = 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA


name: formate + H(+) + menaquinone-8 => CO2 + menaquinol-8


name: Nuclear translocation of p38 MAPK (Homo sapiens)


name: IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Xenopus tropicalis)


name: racemase and epimerase activity, acting on hydroxy acids and derivatives


name: "Acting on hydroxy acids and derivatives"


name: (11Z,14Z,17Z)-eicosatrienoate + O2 => 12-hydroperoxy-(10E,14Z,17Z)-eicosatrienoate


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine


name: (S)-4-hydroxy-2-oxohexanoate = propanal + pyruvate


name: PTPN11 dephosphorylates RUNX1 (Mus musculus)


name: chloride(out) + 2 Na(+)(out) + O-butanoyl-(R)-carnitine(out) <=> chloride(in) + 2 Na(+)(in) + O-butanoyl-(R)-carnitine(in)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] => a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + H(+) + H2O + oxidized [flavodoxin]


name: TFAM binds to mitochondrial promoters (Schizosaccharomyces pombe)


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) <=> (2S)-2-acetolactate + H(+) + NADPH


name: L1 interaction with Integrins (Homo sapiens)


name: formate + H(+) + hydroxymethylphosphonate => 2-hydroxyethylphosphonate + O2


name: an acyl-AMP + diphosphate => a carboxylate + ATP + H(+)


name: 4-methylumbelliferone beta-D-glucuronate(in) + ATP + H2O => 4-methylumbelliferone beta-D-glucuronate(out) + ADP + H(+) + phosphate


name: A + D-gluconate = 2-dehydro-D-gluconate + AH2


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-valine + O2 <=> 2-dehydro-D-glucose + H2O2 + L-valine


name: ARL1 recruits TGN Golgin homodimers (Xenopus tropicalis)


name: Caspase-3 cleaves pro-interleukin-16 (Xenopus tropicalis)


name: CoA + H(+) + hexadecanedioate => H2O + hexadecanedioyl-CoA


name: alpha-D-glucose 6-phosphate => alpha-D-glucose 1-phosphate


name: (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] => (1R,5S)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: beta-catenin is replaced by repression complexes at the promoter (Canis familiaris)


name: (1Z,2S)-2-methylbutanal oxime = (2S)-2-methylbutanenitrile + H2O


name: Activated FGFR2 phosphorylates PLCG1 (Canis familiaris)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Homo sapiens)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Canis familiaris)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + H2O <=> [(1->4)-N-acetyl-beta-D-glucosaminyl](n-2) + N,N'-diacetylchitobiose


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Factor H binds to C3b (Xenopus tropicalis)


name: Tail-anchored protein:ASNA1:ADP binds WRB:CAMLG at the endoplasmic reticulum membrane (Homo sapiens)


name: Activated TP receptor binds G-protein  G13 (Homo sapiens)


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Danio rerio)


name: GCL ligates L-Glu to L-Cys (Rattus norvegicus)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Rattus norvegicus)


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Bos taurus)


name: Activation of cytosolic AMPK by phosphorylation (Homo sapiens)


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Rattus norvegicus)


name: 2 A + canthaxanthin + 3 H2O => 2 AH2 + echinenone + 2 O2


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Rattus norvegicus)


name: Tyrosine is monoiodinated (Rattus norvegicus)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Canis familiaris)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Homo sapiens)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Mus musculus)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-choline => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Bos taurus)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Bos taurus)


name: (R)-carnitinyl-CoA = crotonobetainyl-CoA + H2O


name: USP17 deubiquitinates SUDS3 (Homo sapiens)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Caenorhabditis elegans)


name: (2R)-2,3-bisphosphoglycerate + 2 H(+) => cyclic (2R)-2,3-bisphosphoglycerate + H2O


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside <=> an anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-[(6-O-(E)-4-coumaroyl)glucoside] + CoA


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Canis familiaris)


name: acetyl-CoA + 3 H(+) + 3 malonyl-CoA = 3 CO2 + 4 CoA + tetraacetate lactone


name: LUM (lumican) binds integrin alpha2beta1 (Drosophila melanogaster)


name: Parenchymal atROL translocates to HSCs (Danio rerio)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Homo sapiens)


name: Cleavage of mRNA at the 3'-end (Homo sapiens)


name: C-terminal L-cysteinyl-[HypE protein] + carbamoyl adenylate => AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + H(+)


name: eIF5B:GTP is hydrolyzed and released (Bos taurus)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Gallus gallus)


name: BCHE hydrolyzes ASA- (Drosophila melanogaster)


name: Deubiquitinated PTEN translocates to the cytosol (Drosophila melanogaster)


name: a menaquinol + 4 H(+)(out) + NAD(+) => a menaquinone + 5 H(+)(in) + NADH


name: Orexin 2 receptor can bind orexin-B neuropeptide (Danio rerio)


name: PTK6 phosphorylates ARAP1 (Caenorhabditis elegans)


name: B4GALT5/6 transfer Gal to GlcCer (Homo sapiens)


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Sus scrofa)


name: Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants (Homo sapiens)


name: all-trans-4-oxoretinol + NAD(+) => all-trans-4-oxoretinal + H(+) + NADH


name: diphthine methyl ester-[translation elongation factor 2] + H2O = diphthine-[translation elongation factor 2] + H(+) + methanol


name: SENP1,2,5 proteolytically process SUMO2 (Homo sapiens)


name: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters


name: "Exonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters"


name: Spermidine  => N-acetylated spermidine (Rattus norvegicus)


name: androsterone 3alpha-sulfate(out) + 2 Na(+)(out) <=> androsterone 3alpha-sulfate(in) + 2 Na(+)(in)


name: SOAT can transport taurolithocholate-3-sulphate (Canis familiaris)


name: cob(I)alamin + S-adenosyl-L-methionine <=> methylcob(III)alamin + S-adenosyl-L-homocysteine


name: gamma-tocopherol + S-adenosyl-L-methionine => (+)-alpha-tocopherol + H(+) + S-adenosyl-L-homocysteine


name: STRAP binds phosphorylated TGF-beta receptor complex (Homo sapiens)


name: H2O + O-phospho-D-serine => D-serine + phosphate


name: 8-hydroxycopalyl diphosphate <=> (13R)-manoyl oxide + diphosphate


name: Gq/11-coupled serotonin receptor activity


name: Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) (Bos taurus)


name: extracellularly glycine-gated chloride channel activity


name: GLRA:GLRB:Gly transports extracellular Cl- to cytosol (Homo sapiens)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + tetradecanoyl-CoA = (9Z)-tetradecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SUMOylation of PCNA with SUMO1 (Danio rerio)


name: UBP43 binds IFNAR2 and prevents JAK1 interaction (Gallus gallus)


name: 4-dedimethylamino-4-oxo-anhydrotetracycline + H2O + NADP(+) => 4-hydroxy-6-methylpretetramide + NADPH + O2


name: Activated FGFR4 phosphorylates FRS3 (Danio rerio)


name: UGTs glucuronate APAP to APAP-GlcA (Homo sapiens)


name: (2Z,6Z)-farnesyl diphosphate <=> (E)-gamma-bisabolene + diphosphate


name: (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + (3R)-all-trans-3-hydroxyretinal


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + NADP(+) <=> 1-(9Z)-octadecenoylglycerone 3-phosphate + H(+) + NADPH


name: PTEN undergoes monoubiquitination (Drosophila melanogaster)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Drosophila melanogaster)


name: H2O + N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein] <=> 3-deoxyglucosone + L-lysyl-[protein] + phosphate


name: RORC gene expression is stimulated by RUNX3:CBFB (Homo sapiens)


name: (1R,4R,5S)-acoradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2,6,9-trimethyl-13-oxatetracyclo[6.3.1.1(6,9).0(1,5)]tridecane carbocation + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: VCAM1 binds Integrin alpha4beta1 (Homo sapiens)


name: misfolded CFTR is degraded by the 26S proteasome (Canis familiaris)


name: 3-oxo-3-phenylpropanoate + 2 ADP + 2 H(+) + 2 phosphate => acetophenone + 2 ATP + H2O + hydrogencarbonate


name: ALOX12 oxidises LTA4 to LXA4/B4 (Danio rerio)


name: Release of platelet secretory granule components (Canis familiaris)


name: DNA polymerase epsilon binds at the origin (Schizosaccharomyces pombe)


name: H2O + NAD(+) + rifamycin SV para-naphthoquinone carboxamide => NADH + O2 + rifamycin SV


name: IL21 receptor JAK phosphorylation (Rattus norvegicus)


name: 15alpha-stemmadenine intermediate I + H2O + NADPH = (16R)-deshydroxymethyl-stemmadenine + formate + NADP(+)


name: dopamine + pyruvate = (R)-salsolinol-1-carboxylate + H2O


name: Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)


name: CHRM2 binds CHRM2 antagonists (Xenopus tropicalis)


name: a 4-hydroxynonen-1-ol + NADP(+) = a 4-hydroxynonenal + H(+) + NADPH


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Bos taurus)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Plasmodium falciparum)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Gallus gallus)


name: Formation of Malonyl-CoA from Acetyl-CoA (liver) (Drosophila melanogaster)


name: D-glucosamine 6-phosphate = D-galactosamine 6-phosphate


name: coelenterazine h dioxetanone <=> CO2 + excited coelenteramide h monoanion + H(+)


name: ITP + N-acetyl-D-glucosamine = H(+) + IDP + N-acetyl-D-glucosamine 6-phosphate


name: H2O + L-asparagine + O2 = 2-oxosuccinamate + H2O2 + NH4(+)


name: H2O + L-valine + O2 <=> 3-methyl-2-oxobutanoate + H2O2 + NH4(+)


name: Activated FGFR4:p-FRS bind to PPTN11 (Canis familiaris)


name: CLN3 transports GalCer to plasma membrane (Drosophila melanogaster)


name: SMURF1 ubiquitinates RHOA (Mus musculus)


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Canis familiaris)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Xenopus tropicalis)


name: tBID activates BAK protein (Homo sapiens)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Xenopus tropicalis)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Dictyostelium discoideum)


name: H2O + L-isoleucine-(+)-12-hydroxy-7-isojasmonate <=> L-isoleucine + tuberonate


name: (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] = (R)-mandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (R)-carnitine + tetradecanoyl-CoA = CoA + O-tetradecanoyl-(R)-carnitine


name: Recruitment of CDK11p58 to the centrosomes (Canis familiaris)


name: ADP-riboxanated L-argininyl-[protein] + H(+) + NH4(+) => ADP-1-deoxy-1,O(4)-didehydro-D-ribose + L-arginyl-[protein]


name: TIRAP binds PIP2-rich regions in the plasma membrane (Rattus norvegicus)


name: Association of procollagen type XIX (Drosophila melanogaster)


name: AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Canis familiaris)


name: Exocytosis of secretory granule lumen proteins (Danio rerio)


name: an N-(acyl)-sphingosylphosphocholine + H2O <=> an N-acyl-sphingoid base + H(+) + phosphocholine


name: 2-demethylmenaquinol-13 + S-adenosyl-L-methionine = H(+) + menaquinol-13 + S-adenosyl-L-homocysteine


name: LCAT:spherical HDL complex <=> LCAT + spherical HDL (Bos taurus)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Schizosaccharomyces pombe)


name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression (Bos taurus)


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O => 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: A + chrodrimanin F = AH2 + chrodrimanin H


name: 9alpha-copalyl diphosphate => 9beta-pimara-7,15-diene + diphosphate


name: NFE2 binds the beta globin locus control region (Mus musculus)


name: CDK5:p25 phosphorylates PRDX1 (Homo sapiens)


name: 3 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) = 3 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: PIAS1,3 SUMOylates NR5A1 with SUMO2 (Bos taurus)


name: maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) (Mus musculus)


name: 2-oxobutanoate + CoA + NAD(+) <=> CO2 + NADH + propanoyl-CoA


name: 2-[(E)-caffeoyl]-D-threo-isocitrate(3-) + CoA => (E)-caffeoyl-CoA + D-threo-isocitrate


name: 2-aminophenoxazin-3-one + AH2 + 2 H2O => 2 2-aminophenol + A + O2


name: 2-methylpropanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein]


name: Caspase-8 and FLIP(L) processing at DISC (Canis familiaris)


name: Caspase-mediated cleavage of MST3 (Xenopus tropicalis)


name: Phosphorylation and activation of VAV1 (Sus scrofa)


name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Homo sapiens)


name: quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Homo sapiens)


name: Exocytosis of azurophil granule lumen proteins (Sus scrofa)


name: 12-phosphooxy-(9Z)-octadecenoate + H2O = 12-hydroxy-(9Z)-octadecenoate + phosphate


name: (R)-5-phosphomevalonate + ATP <=> ADP + CO2 + isopentenyl phosphate + phosphate


name: Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 (Gallus gallus)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Homo sapiens)


name: Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Bos taurus)


name: dGTP(out) + UTP(in) <=> dGTP(in) + UTP(out)


name: Phosphorylation of PKC-theta (Sus scrofa)


name: Ca permeable AMPA receptor ligand binding (Mus musculus)


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Mus musculus)


name: Degradation of ubiquitinated SKI/SKIL (Sus scrofa)


name: (25R)-cholest-5-ene-3beta,26-diol + O2 + reduced [NADPH--hemoprotein reductase] = (25R)-cholest-5-en-3beta,7alpha,26-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Gallus gallus)


name: H(+) + NADH + presqualene diphosphate => diphosphate + NAD(+) + squalene


name: p-PKR dimer phosphorylates CDK1 (Drosophila melanogaster)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Sus scrofa)


name: CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Gallus gallus)


name: UGCG transfers glucose to ceramide (Bos taurus)


name: NADPH + 2 O2 + prefumagillin => acetaldehyde + fumagillin + H2O + NADP(+)


name: a 1,2-diacyl-sn-glycerol + an alpha-D-mannosyl-6-(1D-myo-inositol phospho)-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base


name: a globoside GalGb4Cer (d18:1(4E)) + H(+) + UDP => a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose


name: acetate + L-cysteine => hydrogen sulfide + O-acetyl-L-serine


name: ATP + L-glutamine + tRNA(Gln) => AMP + diphosphate + L-glutaminyl-tRNA(Gln)


name: CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin (Xenopus tropicalis)


name: (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-dichlorophenol + CO2 + pyruvate + succinate


name: RBL2 gene expression is stimulated by FOXO1,FOXO3,FOXO4 (Homo sapiens)


name: beta-D-galacturonate + NAD(+) => D-galactaro-1,5-lactone + H(+) + NADH


name: a carboxylate + glycerol + H(+) => a 2-acylglycerol + H2O


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + silphinene = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + silphinene-15-oate


name: H2O + testololactone <=> H(+) + testolate


name: TBK1 phosphorylates STAT6 at Ser407 (Homo sapiens)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPC (Sus scrofa)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Caenorhabditis elegans)


name: SERPINA6 binds PREDN (Rattus norvegicus)


name: 3 hydrogencarbonate(out) + Na(+)(out) <=> 3 hydrogencarbonate(in) + Na(+)(in)


name: a (2S)-2-hydroxycarboxylate + NADP(+) <=> a 2-oxocarboxylate + H(+) + NADPH


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate) + H2O => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate


name: Degradation of ubiquitinated beta catenin by the proteasome (Caenorhabditis elegans)


name: acetate + L-lysyl-[alpha-tubulin] => H2O + N(6)-acetyl-L-lysyl-[alpha-tubulin]


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Rattus norvegicus)


name: ATP + H2O + phosphate(out) = ADP + H(+) + 2 phosphate(in)


name: Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching (Homo sapiens)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Bos taurus)


name: Surface deployment of platelet alpha granule membrane components (Rattus norvegicus)


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Drosophila melanogaster)


name: CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Homo sapiens)


name: TRAF3/or TRAF6 interacts with IPS-1 (Gallus gallus)


name: CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)


name: [(1->3)-alpha-D-glucosyl](n) + phosphate = [(1->3)-alpha-D-glucosyl](n-1) + beta-D-glucose 1-phosphate


name: Aquaporin-9 passively transports glycerol into cell (Bos taurus)


name: H(+) + indole-3-carboxylate <=> CO2 + indole


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Danio rerio)


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)


name: a long-chain fatty acid + ATP + L-cysteinyl-[protein] = AMP + diphosphate + S-(long-chain fatty acyl)-L-cysteinyl-[protein]


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Rattus norvegicus)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate => 1,3-di-(9Z)-hexadecenoylglycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Dictyostelium discoideum)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Dictyostelium discoideum)


name: ATP + L-seryl-[rhodopsin] <=> ADP + H(+) + O-phospho-L-seryl-[rhodopsin]


name: H(+)(out) + N,N-dimethylglycine(out) => H(+)(in) + N,N-dimethylglycine(in)


name: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Bos taurus)


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Gallus gallus)


name: 24,25-dihydrolanosterol + NADP(+) => H(+) + lanosterol + NADPH


name: (R)-4-phosphopantoate + ATP + beta-alanine => (R)-4'-phosphopantothenate + AMP + diphosphate + H(+)


name: LIPs hydrolyze TG to DAG and LCFA (Rattus norvegicus)


name: H(+) + L-arginine + NADH + O2 = H2O + N(omega)-hydroxy-L-arginine + NAD(+)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Rattus norvegicus)


name: diphosphate + sesquisabinene A => (2E,6E)-farnesyl diphosphate


name: CHDH oxidises Cho to BETALD (Mus musculus)


name: DUOX1,2 reduce O2 to H2O2 (Mus musculus)


name: (2E)-geranyl diphosphate = (1S,4R)-camphene + diphosphate


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-dodecanoyl-sn-glycerol + H(+) + phosphocholine


name: peroxisome membrane class-2 targeting sequence binding


name: 4beta-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 4beta,7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTGS2 dimer oxidises EPA to PGH3 (Mus musculus)


name: ICMT methylates S-Farn RAS proteins (Rattus norvegicus)


name: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP => 8-desmethylnovobiocic acid + AMP + diphosphate


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Rattus norvegicus)


name: 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (+)-exo-beta-bergamotene + 3 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 5-dehydro-6-demethoxyfumagillol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: a 2'-deoxyguanosine in DNA + H(+) + lactate => an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Homo sapiens)


name: Phosphorylated OPTN translocates to the nucleus (Bos taurus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Bos taurus)


name: L-tryptophan <=> 2-aminoprop-2-enoate + indole


name: a ubiquinol = a ubiquinone + 2 e(-) + 2 H(+)


name: H2O + malonaldehyde + O2 <=> 3-oxopropanoate + H(+) + H2O2


name: AKT phosphorylates CREB1 (Caenorhabditis elegans)


name: Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Rattus norvegicus)


name: 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate => (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Mus musculus)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Saccharomyces cerevisiae)


name: galactitol 1-phosphate + NAD(+) = H(+) + keto-D-tagatose 6-phosphate + NADH


name: H2O + N-acetylputrescine + O2 = 4-acetamidobutanal + H2O2 + NH4(+)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Drosophila melanogaster)


name: Phosphorylation of PLCgamma by PDGFR (Sus scrofa)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Bos taurus)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Xenopus tropicalis)


name: D-mannonate => 2-dehydro-3-deoxy-D-gluconate + H2O


name: H(+) + phosphate + thiamine diphosphate => H2O + thiamine triphosphate


name: CTP(in) + GTP(out) => CTP(out) + GTP(in)


name: 2 Na(+)(out) + uridine(out) => 2 Na(+)(in) + uridine(in)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Canis familiaris)


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Mus musculus)


name: HEXA cleaves the terminal GalNAc from DS (Rattus norvegicus)


name: 3-hydroxyphenylacetate + H(+) + NADPH + O2 = H2O + homogentisate + NADP(+)


name: (+)-thujan-3-ol + NADP(+) => (+)-thujan-3-one + H(+) + NADPH


name: gentamicin X2 + methylcob(III)alamin + S-adenosyl-L-methionine => 5'-deoxyadenosine + cob(III)alamin + geneticin + L-methionine


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Plasmodium falciparum)


name: hypoxanthine + NH4(+) => adenine + H(+) + H2O


name: TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome (Homo sapiens)


name: HSD17B13 binds lipid droplets (Saccharomyces cerevisiae)


name: ATP-dependent H2AZ histone chaperone activity


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Canis familiaris)


name: 5alpha-androst-1-ene-3,17-dione + H2O = 1-hydroxy-5alpha-androstan-3,17-dione


name: [prokaryotic ubiquitin-like protein]-C-terminal-L-glutamine + H2O => [prokaryotic ubiquitin-like protein]-C-terminal-L-glutamate + NH4(+)


name: 3',5'-cyclic AMP(out) => 3',5'-cyclic AMP(in)


name: PAQR3 binds inactive RAFs (Rattus norvegicus)


name: IRE1 binds IRE1 forming dimer (Schizosaccharomyces pombe)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => diphosphate + neoverrucosan-5beta-ol


name: (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate => di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate


name: avenacoside B + H2O => 26-desgluco-avenacoside B + D-glucose


name: emodin + H(+) + H2O => emodin anthrone + O2


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate <=> ectocarpin A + H2O


name: (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate <=> 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O


name: eIF5B:GTP is hydrolyzed and released (Drosophila melanogaster)


name: GLYAT-like proteins transfer glycine to ST-CoA to form SUA (Canis familiaris)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Danio rerio)


name: NTPDase8 hydrolyzes nucleoside triphosphates (Mus musculus)


name: L-glutamate + NH4(+) => H2O + L-glutamine


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Plasmodium falciparum)


name: (20S)-ginsenoside Rd + H(+) + UDP => (20S)-ginsenoside F2 + UDP-alpha-D-glucose


name: nocardicin E + S-adenosyl-L-methionine => H(+) + isonocardicin A + S-methyl-5'-thioadenosine


name: 3-oxopropanoate + CoA + H2O + NAD(+) <=> acetyl-CoA + H(+) + hydrogencarbonate + NADH


name: (S)-malate(out) + citrate(in) => (S)-malate(in) + citrate(out)


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Bos taurus)


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,3-di-(9Z-octadecenoyl)-glycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-(9Z-octadecenoyl)-sn-glycerol


name: diphthine methyl ester-[translation elongation factor 2] + H2O => diphthine-[translation elongation factor 2] + H(+) + methanol


name: PKM dephosphorylates PEP to PYR (Sus scrofa)


name: Dentin phosphoprotein binds integrin alphaVbeta1 (Homo sapiens)


name: 15-dehydro-prostaglandin I2 + H(+) + NADPH => NADP(+) + prostaglandin I2


name: Translocation of PLC-gamma1 to PIP2 (Drosophila melanogaster)


name: SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Homo sapiens)


name: AH2 + O2 + preaustinoid A <=> A + H2O + preaustinoid A1


name: an S-substituted L-cysteine + H2O => a thiol + NH4(+) + pyruvate


name: (Z)-phenylacetaldehyde oxime => (E)-phenylacetaldehyde oxime


name: 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+) => ATP + D-ribose 5-phosphate


name: a ubiquinone + H(+) + NADH <=> a ubiquinol + NAD(+)


name: 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol) => 2 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3  phosphorylates STAT1,STAT3 (Gallus gallus)


name: Activated ATM phosphorylates ABL1 (Rattus norvegicus)


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Sus scrofa)


name: IDO1 dioxygenates L-Trp to NFK (Bos taurus)


name: FAD + H(+) + hexanoyl-CoA <=> (2E)-hexenoyl-CoA + FADH2


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Canis familiaris)


name: MITF-M dimer binds the CDKN2A gene (Homo sapiens)


name: 3-phosphooxypyruvate + L-glutamate => 2-oxoglutarate + O-phospho-L-serine


name: O2 + quinine + reduced [NADPH--hemoprotein reductase] = 3-hydroxyquinine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Latent TGF-beta-3 binds integrins (Mus musculus)


name: 2-methoxyestrone + UDP-alpha-D-glucuronate <=> 2-methoxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Xenopus tropicalis)


name: 4-hydroxystyrene + CO2 => (E)-4-coumarate + H(+)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z-octadecenoate) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + cholesterol


name: MITF-M-dependent CCNB1 gene expression (Homo sapiens)


name: DNA-PKcs autophosphorylates (Canis familiaris)


name: PLK2 phosphorylates CENPJ (Gallus gallus)


name: Internalisation of the insulin receptor (Canis familiaris)


name: H2O + trihexadecanoylglycerol = 2,3-dihexadecanoyl-sn-glycerol + H(+) + hexadecanoate


name: 5-pyridoxate + NADPH + O2 => 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+)


name: 2xPPCS ligates PPanK with Cys (Danio rerio)


name: CUL1, SKP1, FBXL5 bind (Saccharomyces cerevisiae)


name: LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] (Rattus norvegicus)


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Mus musculus)


name: Caspase-mediated cleavage of occludin (Sus scrofa)


name: beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol => cholesteryl 3-beta-D-glucoside + N-(9Z-octadecenoyl)-sphing-4-enine


name: 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Nef Binds and activates the Src-family tyrosine kinase Fyn (Homo sapiens)


name: Laminins:Nidogens binds HSPG2 (Homo sapiens)


name: (11Z)-octadecenoyl-CoA + H2O <=> (11Z)-octadecenoate + CoA + H(+)


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Caenorhabditis elegans)


name: bis(beta-D-glucosyl) crocetin + UDP-alpha-D-glucose <=> beta-D-gentiobiosyl beta-D-glucosyl crocetin + H(+) + UDP


name: HYKK phosphorylates 5HLYS (Drosophila melanogaster)


name: PTPN1 dephosphorylates PTK6 (Homo sapiens)


name: Initial resection of double-strand break ends (Mus musculus)


name: Syndecans 1, 2 & 4 bind VTN (Mus musculus)


name: RAC3 GAPs stimulate RAC3 GTPase activity (Bos taurus)


name: CFHR dimers bind C3b (Rattus norvegicus)


name: FGFRL1 binds SPRED1/2 (Xenopus tropicalis)


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Rattus norvegicus)


name: EP400 binds CDKN1A promoter (Homo sapiens)


name: 2-oxobutanoate + methanethiol + NH4(+) => H2O + L-methionine


name: 3-methylbutanal reductase (NADPH) activity


name: ME1 tetramer decarboxylates MAL to PYR (Sus scrofa)


name: NOSTRIN mediated translocation of eNOS from plasma membrane (Homo sapiens)


name: (S)-1-phenylethylamine + H2O + NAD(+) <=> acetophenone + H(+) + NADH + NH4(+)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Saccharomyces cerevisiae)


name: Ghrelin O-acyltransferase octanoylates Proghrelin (Sus scrofa)


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Caenorhabditis elegans)


name: (E)-feruloyl-AMP + CoA = (E)-feruloyl-CoA + AMP + H(+)


name: H2O + L-glutamate + O2 = 2-oxoglutarate + H2O2 + NH4(+)


name: PKR binds activating host RNA (Sus scrofa)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Rattus norvegicus)


name: 2 S-adenosyl-L-methionine + squalene => 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + 9-hydroxy-octadecanoate <=> 1,3-di-(9Z,12Z)-octadecadienoylglycerol + 9-(9Z,12Z-octadecadienoyloxy)-octadecanoate


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphate


name: diphosphate + phomopsene => (2E,6E,10E)-geranylgeranyl diphosphate


name: (2E,6E)-farnesyl diphosphate <=> (+)-gamma-cadinene + diphosphate


name: PTK2 binds activated EGFR (Mus musculus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine


name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria (Canis familiaris)


name: Creatine transport across the plasma membrane (Xenopus tropicalis)


name: 1-hydroxy-5alpha-androstan-3,17-dione + A => 5alpha-androstan-1,3,17-trione + AH2


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Canis familiaris)


name: Myosin phosphatase dephosphorylates PLK1 (Gallus gallus)


name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Xenopus tropicalis)


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Drosophila melanogaster)


name: a 3-oxosteroid + H(+) + NADPH => a 3beta-hydroxysteroid + NADP(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: SRD5A3 dehydrogenates TEST to DHTEST (Canis familiaris)


name: MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) (Schizosaccharomyces pombe)


name: PTK6 translocates to the nucleus (Xenopus tropicalis)


name: H(+) + NADPH + O2 + protoviolaceinate = H2O + NADP(+) + violaceinate


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Homo sapiens)


name: 2 5'-deoxyadenosine + a bacteriochlorophyllide f + 2 H(+) + 2 L-methionine => a bacteriochlorophyllide d + H2O + 2 S-adenosyl-L-methionine


name: N(2)-(1-hydroxy-2-oxopropyl)-GDP => GDP + methylglyoxal


name: ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 (Mus musculus)


name: NR3C1 binds NR3C1 agonists (Mus musculus)


name: IL1F10(?-152) binds IL1RAPL1 (Mus musculus)


name: USP3,SAGA deubiquitinate Histone H2A,H2B (Sus scrofa)


name: pre-sodorifen diphosphate <=> diphosphate + sodorifen


name: PD1n-3, PD2n-3 translocate from cytosol to extracellular region (Homo sapiens)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Canis familiaris)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Xenopus tropicalis)


name: Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Mus musculus)


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Canis familiaris)


name: STAT5 is recruited by JAK2 (Mus musculus)


name: ADP + H(+) + phosphate + urea-1-carboxylate => ATP + hydrogencarbonate + urea


name: (4R)-hydroxysphinganine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoyl-(4R)-hydroxysphinganine


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Mus musculus)


name: maltose + H2O => 2 D-glucose (maltase-glucoamylase) (Caenorhabditis elegans)


name: PLK1 phosphorylates GTSE1 (Rattus norvegicus)


name: SRD5A3 dehydrogenates TEST to DHTEST (Saccharomyces cerevisiae)


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] => H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein]


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Bos taurus)


name: ORC1 translocates to the nucleus (Saccharomyces cerevisiae)


name: Phosphorylation of SHP2 by SFKs (Sus scrofa)


name: nsp12 acquires Fe-S cluster cofactors (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-acyl-4-hydroxy-15-methylhexadecasphinganine => a 1,2-diacyl-sn-glycerol + N-acyl-4-hydroxy-15-methylhexadecasphinganine-1-phosphocholine


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Drosophila melanogaster)


name: a fatty aldehyde + CO2 + H2O => a (2R)-2-hydroperoxy fatty acid + H(+)


name: HOMER binds SHANK proteins (Homo sapiens)


name: (R)-noradrenaline(in) + 2 H(+)(out) <=> (R)-noradrenaline(out) + 2 H(+)(in)


name: CYP2A13 oxidises AFM1 to AFM1E (Drosophila melanogaster)


name: (E,E)-2,4-hexadien-1-ol + NADP(+) = (E,E)-2,4-hexadienal + H(+) + NADPH


name: Active MTORC1 phosphorylates ULK1 (Rattus norvegicus)


name: CoA + O-fatty acyl-L-seryl-[protein] => a fatty acyl-CoA + L-seryl-[protein]


name: Keratin filaments bind cell-cell adhesion complexes (Xenopus tropicalis)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Sus scrofa)


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Mus musculus)


name: GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Canis familiaris)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate => 5-oxo-(6E,8Z,11Z,14Z)-eicosatetraenoate + H2O


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Mus musculus)


name: Activated FGFR3 phosphorylates SHC1 (Rattus norvegicus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Bos taurus)


name: Association of NuMA with microtubules (Sus scrofa)


name: The phagophore extends from the PIP3-enriched structure (Schizosaccharomyces pombe)


name: O2 + piceatannol = 3,4-dihydroxybenzaldehyde + 3,5-dihydroxybenzaldehyde


name: snRNP nuclear import and release (Gallus gallus)


name: PSAP(195-273) forms a dimer (Homo sapiens)


name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Dictyostelium discoideum)


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Mus musculus)


name: H(+) + N-hexadecanoylsphing-4-enine + phosphocholine => H2O + N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Danio rerio)


name: (5Z)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: SORD oxidizes D-sorbitol to Fru (Caenorhabditis elegans)


name: ATP + H2O + voriconazole(in) => ADP + H(+) + phosphate + voriconazole(out)


name: 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 7-oxocholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADH + O2 + orcinol <=> 2,3,5-trihydroxytoluene + H2O + NAD(+)


name: FOXP3 gene expression is stimulated by RUNX1:CBFB (Homo sapiens)


name: CYB5A:heme reduces Asc.- to AscH- (Rattus norvegicus)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Canis familiaris)


name: LMF1,2 bind LIPC dimer (Xenopus tropicalis)


name: 19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] => 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: SUCLG1/G2 cleaves succinyl-CoA (Xenopus tropicalis)


name: ALOX5 oxidises EPA to 5-HEPE (Homo sapiens)


name: Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG (Homo sapiens)


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Sus scrofa)


name: 4-nitro-6-oxohepta-2,4-dienedioate => 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2 => (1-deoxy-D-fructos-1-yl)amine + an aldehyde + H2O2


name: acetyl-CoA + hexanoyl-CoA => 3-oxooctanoyl-CoA + CoA


name: 5alpha-cholest-8,14-dien-3beta-ol + H(+) + NADPH = 5alpha-cholest-8-en-3beta-ol + NADP(+)


name: HGSNAT oligomer acetylates Heparan chain(1) (Dictyostelium discoideum)


name: TRPs transport extracellular Ca2+ to cytosol (Dictyostelium discoideum)


name: Deamination at C6 position of adenosine in Editosome (ADAR2) (Mus musculus)


name: 8-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase] <=> 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Rattus norvegicus)


name: 6-deoxocastasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = castasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: chloride(out) + Cs(+)(in) + 2 hydrogencarbonate(in) <=> chloride(in) + Cs(+)(out) + 2 hydrogencarbonate(out)


name: 1D-myo-inositol hexakisphosphate + H2O <=> 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Dictyostelium discoideum)


name: Autophosphorylation of PAK (Canis familiaris)


name: Dissociation of L13a from the 60s ribosomal subunit (Xenopus tropicalis)


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + sesquithujene


name: PYGB b dimer:AMP complex <=> PGYB dimer, b form + 2 AMP (Homo sapiens)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Danio rerio)


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H(+) + ubiquinol-10 => trans-4-hydroxy-L-proline + ubiquinone-10


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + pentadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA


name: RHOD binds effectors at the Golgi membrane (Sus scrofa)


name: alfacalcidol + O2 + reduced [NADPH--hemoprotein reductase] = calcitriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + L-isoleucine + O2 => (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: SUMOylation of HIPK2 with SUMO1 (Gallus gallus)


name: GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP (Homo sapiens)


name: cis-beta-D-glucosyl-2-hydroxycinnamate + H2O = beta-D-glucose + cis-2-coumarate


name: leukotriene B4 12-hydroxy dehydrogenase activity


name: CAD hexamer transforms CAP to N-carb-L-Asp (Mus musculus)


name: 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+) => an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: 17beta-estradiol + UDP-alpha-D-glucuronate => 17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Bos taurus)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Schizosaccharomyces pombe)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)


name: GBA3 hydrolyzes GlcCer (cytosol) (Canis familiaris)


name: IL19 binds IL20RA:JAK1:IL20RB (Rattus norvegicus)


name: Formation of P-TEFb complex (Sus scrofa)


name: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O = 2-formylglutarate + NH4(+)


name: C2CD3 binds the mother centriole (Rattus norvegicus)


name: p-Y701-STAT1 binds p-Y705-STAT3 (Sus scrofa)


name: RHOF binds effectors at the plasma membrane (Drosophila melanogaster)


name: 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Dictyostelium discoideum)


name: Aquaporins passively transport water out of cells (Sus scrofa)


name: (20S)-ginsenoside Rg3 + 2 D-glucose => (20S)-ginsenoside Rb1 + 2 H2O


name: Caspase mediated cleavage of C-IAP1 (Rattus norvegicus)


name: Formation of CDK4/6:CCND complexes (Schizosaccharomyces pombe)


name: a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 <=> a (8S,9R)-5-glyceryl-2'-deoxycytidine in DNA + CO2 + glyoxylate


name: Binding of RRN3 to RNA Polymerase I (Homo sapiens)


name: DENND5A,B exchange GTP for GDP on RAB39 (Drosophila melanogaster)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Canis familiaris)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Saccharomyces cerevisiae)


name: PTEN gene transcription is stimulated by TP53 (Homo sapiens)


name: PIAS1,3 SUMOylate NRIP1 with SUMO1 (Xenopus tropicalis)


name: (3R)-hydroxyhexadecanoyl-CoA => (2E)-hexadecenoyl-CoA + H2O


name: (Z)-(indol-3-yl)-N-(sulfonatooxy)methanimidothioate => (indol-3-yl)acetonitrile + sulfate + sulfur


name: P4HB forms mixed disulphides with Hh precursors (Sus scrofa)


name: alpha-humulene + O2 + reduced [NADPH--hemoprotein reductase] = 10-hydroxy-alpha-humulene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: chloramphenicol(out) + H(+)(in) => chloramphenicol(in) + H(+)(out)


name: (3R)-3-hydroxy-L-aspartate <=> NH4(+) + oxaloacetate


name: PRC2 trimethylates histone H3 at lysine-27 (Sus scrofa)


name: CoA + H(+) + N-eicosanoyl-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + eicosanoyl-CoA


name: (S)-2-ureidoglycine + H2O <=> (S)-ureidoglycolate + NH4(+)


name: SUMOylation of Histone H4 with SUMO1 (Sus scrofa)


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Gallus gallus)


name: a ganglioside GT3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GT2 + H(+) + UDP


name: SARS-CoV-2 6 binds NUP98:RAE1 within NPC (Homo sapiens)


name: G13 activation by TP receptor (Rattus norvegicus)


name: HK1 phosphorylates Mannose to Man6P (Rattus norvegicus)


name: PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Sus scrofa)


name: CDKN2A (p14-ARF) SUMOylates WRN with SUMO1 (Homo sapiens)


name: phosphate + presqualene alcohol => H2O + presqualene phosphate


name: (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O


name: (12Z)-10-hydroxyoctadecenoate => (9Z,12Z)-octadecadienoate + H2O


name: coenzyme F420-0:L-glutamate ligase activity


name: SPHK1 phosphorylates sphingoid (Dictyostelium discoideum)


name: (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine <=> 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoserine + CoA


name: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate <=> 10-deacetyl-2-debenzoylbaccatin III


name: a long-chain (3R)-hydroxyacyl-CoA <=> a long-chain (2E)-enoyl-CoA + H2O


name: peonidin + UDP-alpha-D-galactose <=> peonidin 3-O-beta-D-galactoside + UDP


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Mus musculus)


name: adenosylcob(III)inamide phosphate + GDP + H(+) => adenosylcob(III)inamide + GTP


name: 5-dehydro-6-demethoxyfumagillol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => (+)-exo-beta-bergamotene + 3 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: RHOT2 binds effectors at the mitochondrial outer membrane (Saccharomyces cerevisiae)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)


name: 7,8-dihydroneopterin 3'-triphosphate => 7,8-dihydromonapterin 3'-triphosphate


name: O2 + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O2


name: Fibrillin C-terminal processing (Sus scrofa)


name: acetate + ATP + holo-[ACP] <=> acetyl-[ACP] + AMP + diphosphate


name: MAPK1,(MAPK3) phosphorylates NPAS4 (Homo sapiens)


name: phenol + S-adenosyl-L-methionine => anisole + H(+) + S-adenosyl-L-homocysteine


name: ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG (Homo sapiens)


name: 2 hydrogencarbonate(out) + sulfate(in) <=> 2 hydrogencarbonate(in) + sulfate(out)


name: (9Z)-octadecenoate + L-phenylalanine = H2O + N-(9Z-octadecenoyl)-L-phenylalanine


name: (2E,6E)-farnesyl diphosphate = (1E,4E)-germacrene B + diphosphate


name: Phosphorylation of beta and gamma subunits by LYN (Canis familiaris)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O => 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + H(+) + phosphoethanolamine


name: AMP + diphosphate + H(+) + L-asparagine + L-glutamate => ATP + H2O + L-aspartate + L-glutamine


name: Abortive termination of elongation after arrest (Drosophila melanogaster)


name: Active ALK recruits PI3K (Canis familiaris)


name: I(1,4,5)P3 binds ITPR3 tetramer (Dictyostelium discoideum)


name: GAA hydrolyzes lysosomal glycogen (Canis familiaris)


name: 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + CO2 + H2O + L-methionine => N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine


name: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively (Mus musculus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + cholesterol => 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z-octadecenoate)


name: 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + eicosanoyl-CoA


name: Collagen type XVIII endostatin release (Bos taurus)


name: beta-D-fructose 2-phosphate + phosphate => beta-D-fructose 2,6-bisphosphate + H2O


name: SREBP1A,1C binds the FASN promoter (Homo sapiens)


name: SPPL2a/b cleaves TNF(1-76) (Mus musculus)


name: D-glucose 6-phosphate + NAD(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADH


name: H2O + N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine <=> H(+) + L-aspartate + N-acetyl-beta-D-glucosaminylamine


name: PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) (Schizosaccharomyces pombe)


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Sus scrofa)


name: L-Glutamate loading of synaptic vesicle (Danio rerio)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Drosophila melanogaster)


name: 1,4-menthane-3,8-diol + H2O + NADP(+) => (-)-menthol + H(+) + NADPH + O2


name: H(+)(out) + L-aspartate(in) + L-glutamate(out) <=> H(+)(in) + L-aspartate(out) + L-glutamate(in)


name: CyP60 chaperones Basigin (Xenopus tropicalis)


name: a long-chain fatty acid + ethanolamine => H2O + N-(long-chain fatty acyl)ethanolamine


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Canis familiaris)


name: C4 deamination of cytidine (Mus musculus)


name: Release of docked serotonin loaded synaptic vesicle (Homo sapiens)


name: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + CMP + H(+) => a neolactoside nLc4Cer + CMP-N-acetyl-beta-neuraminate


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Drosophila melanogaster)


name: TFAP2A homodimer binds CDKN1A (p21) gene (Homo sapiens)


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Rattus norvegicus)


name: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate


name: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2 reduced [2Fe-2S]-[ferredoxin]


name: TFRC dimer binds 2xholoTF (Gallus gallus)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Canis familiaris)


name: ATP + L-glutamate + tRNA(Glx) <=> AMP + diphosphate + L-glutamyl-tRNA(Glx)


name: 1D-myo-inositol 1,4,5-trisphosphate + 2 ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 2 ADP + 2 H(+)


name: O2 + phylloquinone + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein reductase]


name: 5-HT2 receptor can bind serotonin (Homo sapiens)


name: 6-deoxycathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => campestanol + O2 + reduced [NADPH--hemoprotein reductase]


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Bos taurus)


name: Exocytosis of ficolin-rich granule lumen proteins (Mus musculus)


name: CFTR transports Cl- from cytosol to extracellular region (Danio rerio)


name: H(+) + soyasapogenol A 3-O-beta-D-glucuronate + UDP => soyasapogenol A + UDP-alpha-D-glucuronate


name: PDP1,2 dephosphorylate p-lipo-PDH (Canis familiaris)


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Xenopus tropicalis)


name: Activation of conventional Protein Kinase C (Danio rerio)


name: Activated TGFBR1 cannot phosphorylate SMAD2 and SMAD3 Phosphorylation Motif Mutants (Homo sapiens)


name: S1PR1 binds S1PR1 agonists (Mus musculus)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Danio rerio)


name: terpentedienyl diphosphate = diphosphate + terpentetriene


name: (2Z)-2-hydroxypenta-2,4-dienoate + fumarate + H(+) => (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O


name: MME:Zn2+ binds sacubitrilat (Xenopus tropicalis)


name: H2O + substance P => L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-6)


name: 4-hydroxy-6-(15-hydroxypentadecyl)-pyran-2-one + 2 CO2 + 3 CoA => 16-hydroxyhexadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: SUMOylation of MKL1 with SUMO1 (Sus scrofa)


name: 5-amino-2-oxopentanoate + H2O2 + NH4(+) => H2O + L-ornithine + O2


name: acenaphthene-1,2-dione + 2 H(+) + 2 NADPH => (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+)


name: ADRM1:26S proteaseome binds UCHL5 (Drosophila melanogaster)


name: NTPDase7 hydrolyzes nucleoside triphosphates (Homo sapiens)


name: STON2 is neddylated (Dictyostelium discoideum)


name: L-threonine O-3-phosphate phosphatase activity


name: guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine <=> H(+) + N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine


name: H(+) + N(omega)-methyl-L-arginine + NADH + O2 = H2O + N(delta)-hydroxy-N(omega)-methyl-L-arginine + NAD(+)


name: 25-hydroxyvitamin D3 sulfate(in) + n H(+)(in) => 25-hydroxyvitamin D3 sulfate(out) + n H(+)(out)


name: GAB1 phosphorylation by EGFR kinase (Rattus norvegicus)


name: Activation of NIK (Saccharomyces cerevisiae)


name: 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) = 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Sus scrofa)


name: DNMT1-dependent PTPN6 gene silencing (Homo sapiens)


name: 2-methylfumaryl-CoA + H2O => (2R,3S)-beta-methylmalyl-CoA


name: Interaction of Csk with PAG (Bos taurus)


name: CPO transforms COPRO3 to PPGEN9 (Saccharomyces cerevisiae)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)


name: a phosphatidylglycerol phosphate + H2O => a phosphatidylglycerol + phosphate


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Xenopus tropicalis)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> 1,6-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: LEAP2 binds bacteria (Rattus norvegicus)


name: (25R)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (25R)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: RAPGEF1 binds CRK,CRKL (Xenopus tropicalis)


name: RUNX1:CBFB binds CREBBP (Drosophila melanogaster)


name: Cleavage of mRNA at the 3'-end (Gallus gallus)


name: S-Farn-Me KRAS4B binds calmodulin (Homo sapiens)


name: (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+) => 3-chlorocatechol + H(+) + NADH


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Danio rerio)


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Canis familiaris)


name: MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Homo sapiens)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Drosophila melanogaster)


name: succinate-CoA ligase (ADP-forming) activity


name: PNP trimer transforms RBV to T-CONH2 (Homo sapiens)


name: H2O + N-acyl-15-methylhexadecasphing-4-enine = 15-methylhexadecasphing-4-enine + a fatty acid


name: 4 H(+) + N(6)-dimethyladenosine(N)/N(6)-dimethyladenosine(N+1) in rRNA + 4 S-adenosyl-L-homocysteine => adenosine(N)/adenosine(N+1) in rRNA + 4 S-adenosyl-L-methionine


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Saccharomyces cerevisiae)


name: Recruitment of SHC1 is mediated by Y593 of the common beta chain (Homo sapiens)


name: Cleavage of ERBB4m80 by gamma-scretase complex (Danio rerio)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O <=> a fatty acid + an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+)


name: PGH2 is reduced to PGF2a by AKR1C3 (Bos taurus)


name: ASA-,ST translocate from cytosol to ER lumen of hepatocytes (Homo sapiens)


name: 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH => aurachin B + H2O + NAD(+)


name: 4-hydroxybenzoyl-5'-AMP + holo-[4-hydroxyphenylalkanoate synthase] <=> 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + H(+)


name: 2-(glutathione-S-yl)-hydroquinone + glutathione => glutathione disulfide + hydroquinone


name: LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Gallus gallus)


name: 3-oxopropanoate + 2 H(+) + NADH => H2O + malonaldehyde + NAD(+)


name: a carboxylate + 2 H(+) + NADPH => an aldehyde + H2O + NADP(+)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Danio rerio)


name: Phosphorylation of Cx43 by c-src (Mus musculus)


name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Sus scrofa)


name: an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-N-acetyl-alpha-D-galactosamine => an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H(+) + UDP


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Bos taurus)


name: 2-(acetamidomethylene)succinate + NAD(+) => 3-hydroxy-2-methylpyridine-5-carboxylate + NADH + O2


name: Formation of TSC1:TSC2 complex (Bos taurus)


name: NLRP3 activation by small molecules (Bos taurus)


name: p-Y705,S727-STAT3 dimerizes (Drosophila melanogaster)


name: AH2 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + serpentine => A + ajmalicine + O2 + reduced [NADPH--hemoprotein reductase]


name: FGFR3c binds to FGF (Caenorhabditis elegans)


name: cyclohexanol + NAD(+) <=> cyclohexanone + H(+) + NADH


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Rattus norvegicus)


name: ALB binds extracellular heme (Canis familiaris)


name: Interaction of particulate antigens with dendritic cell receptors (Homo sapiens)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Rattus norvegicus)


name: 4-hydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 = 2,4-dibromophenol + CO2 + 4 H2O + 2 NADP(+)


name: Integrator complex processes the 3' end of snRNA (Sus scrofa)


name: FYN phosphorylates PAK2 (Canis familiaris)


name: GDIs block activation of RHOG (Xenopus tropicalis)


name: cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: DCC interaction with Ezrin (Drosophila melanogaster)


name: cytoskeleton-nuclear membrane anchor activity


name: H2O + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2) => beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: Activated PCLG1 dissociates from NTRK2 (Xenopus tropicalis)


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Mus musculus)


name: VLDLR:PCSK9 binds Clathrin-coated vesicles (Sus scrofa)


name: CMP-5'-(N-acetyl-N-hydroxy-3-aminopropyl)phosphonate + H2O => 3-(N-acetyl-N-hydroxy)aminopropylphosphonate + CMP + H(+)


name: STAT binds to the active receptor (Gallus gallus)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Homo sapiens)


name: PSD-95 binds NMDA receptor (Rattus norvegicus)


name: 2 GTP + H(+) => diphosphate + P(1),P(4)-bis(5'-guanosyl) tetraphosphate


name: bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer (Sus scrofa)


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Sus scrofa)


name: 2-oxoglutarate + L-histidyl-[ankyrin-repeat domain protein] + O2 <=> (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: DHAP is converted to G3P by GPD1/GPD1L (Schizosaccharomyces pombe)


name: 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O <=> (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+)


name: Interaction of Tie2 with Ang1 (Bos taurus)


name: a 3-oxoacyl-[ACP] + acetyl-[ACP] + H2O <=> a 3-carboxymethyl-3-hydroxy-acyl-[ACP] + H(+) + holo-[ACP]


name: RPA binds to the Flap on the C-strand (Mus musculus)


name: TGFB1,TGFB2 bind TGFBR3 (Canis familiaris)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Gallus gallus)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Canis familiaris)


name: Formation of anchoring fibrils (Rattus norvegicus)


name: H(+) + methanol + sulfate => H2O + monomethyl sulfate


name: CysS248-MPST:TXN2 dissociates (Rattus norvegicus)


name: Spermine  => N-acetylated spermine (Saccharomyces cerevisiae)


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)


name: SUMOylation of PCNA with SUMO1 (Xenopus tropicalis)


name: 2 H2O + phenylpropanonitrile => 3-phenylpropanoate + NH4(+)


name: TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC (Drosophila melanogaster)


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Bos taurus)


name: L-arginine(in) + L-lysine(out) <=> L-arginine(out) + L-lysine(in)


name: chloride(out) + 2 hydrogencarbonate(in) + Li(+)(in) <=> chloride(in) + 2 hydrogencarbonate(out) + Li(+)(out)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Bos taurus)


name: lithocholate + NADP(+) <=> 3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: ATP + Cd(2+)(in) + H2O => ADP + Cd(2+)(out) + H(+) + phosphate


name: formyl-CoA + pentadecanal => (2R)-hydroxyhexadecanoyl-CoA


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (24S)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CHEK1 phosphorylates RAD51 (Canis familiaris)


name: NEK9 phosphorylates NEK6/NEK7 (Bos taurus)


name: KIR2DL2/3 interacting with HLA-C group 1 (Cw4) (Mus musculus)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Danio rerio)


name: IL10 positively regulates extracellular inflammatory mediators (Homo sapiens)


name: Activation of proMMP11 by FURIN (Homo sapiens)


name: GOLGA2 phosphorylated by CDK1 is unable to promote fusion of ER to Golgi transport vesicles with cis-Golgi (Homo sapiens)


name: 6beta-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase]


name: L-cystine(in) + Na(+)(in) = L-cystine(out) + Na(+)(out)


name: HJURP:CENPA complex localizes to the centromere (Bos taurus)


name: PhosphoChREBP (Thr 653) is exported to cytosol (Caenorhabditis elegans)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Homo sapiens)


name: snRNA 2'-O-ribose methylation guide activity


name: Melanocortin receptors bind melanocortins (Rattus norvegicus)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine => 1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerol + a sphingomyelin


name: 3-demethylubiquinol-7 + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + ubiquinol-7


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Caenorhabditis elegans)


name: cyclohexanone + H(+) + NADPH + O2 = H2O + hexano-6-lactone + NADP(+)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Drosophila melanogaster)


name: H(+)(out) + L-cystine(out) <=> H(+)(in) + L-cystine(in)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Mus musculus)


name: The Interleukin 1 receptor complex binds Tollip (Sus scrofa)


name: a ganglioside GD3 + CMP-N-acetyl-beta-neuraminate => a ganglioside GT3 + CMP + H(+)


name: 16alpha,17beta-estriol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 16alpha,17beta-estriol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate


name: RUNX1:CBFB binds the LGALS3 gene promoter (Homo sapiens)


name: p-S54-PDE4B hydrolyses cAMP (Rattus norvegicus)


name: ATP12A:ATP4B exchanges K+ for H+ (Homo sapiens)


name: snRNA Cap hypermethylation (Caenorhabditis elegans)


name: (9Z)-octadecenoate + glycine = H2O + N-(9Z-octadecenoyl)glycine


name: 5alpha-androst-1-ene-3,17-dione + A = AH2 + androsta-1,4-diene-3,17-dione


name: Mg2+ binds GRIN1:GRIN2 NMDA receptors (Homo sapiens)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycerol 3-phosphate + choline + H(+)


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Canis familiaris)


name: Expression of ADP-ribosylation factor 1 (Homo sapiens)


name: a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate = a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate


name: 3-dehydroshikimate + a quinol => a quinone + shikimate


name: Tetrastatin binds integrin alphaVbeta3 (Canis familiaris)


name: (S)-malate(in) + H(+)(out) + phosphate(out) => (S)-malate(out) + H(+)(in) + phosphate(in)


name: FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) (Drosophila melanogaster)


name: UCKL1 phosphorylates urindine, cytidine (Drosophila melanogaster)


name: (-)-pinoresinol + H(+) + NADPH => (-)-lariciresinol + NADP(+)


name: 2-(prostaglandin H2)-sn-glycero-3-phosphocholine = 2-(prostaglandin E2)-sn-glycero-3-phosphocholine


name: dimethylallyl diphosphate + L-tyrosine <=> 4-O-dimethylallyl-L-tyrosine + diphosphate


name: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Danio rerio)


name: microcin transmembrane transporter activity


name: TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Homo sapiens)


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Xenopus tropicalis)


name: USP2 deubiquitinates MDM2,MDM4 (Rattus norvegicus)


name: RAC3 translocates to the endoplasmic reticulum membrane (Gallus gallus)


name: Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) (Bos taurus)


name: RNA(n)-3'-adenine ribonucleotide <=> 2',3'-cyclophospho-AMP + RNA(n)


name: Arachidonic acid is oxidised to PGG2 by PTGS1 (Homo sapiens)


name: Loading and methylation of Sm proteins onto SMN Complexes (Mus musculus)


name: beta-D-fructose + beta-D-glucose 6-phosphate => H2O + sucrose 6(F)-phosphate


name: diphosphate + fusoxypene C => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out)


name: MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370 (Homo sapiens)


name: 1-eicosanoylglycerol + H2O = eicosanoate + glycerol + H(+)


name: deoxyherqueinone + H(+) + NADPH + O2 = H2O + herqueinone + NADP(+)


name: (9Z,12Z)-octadecadienoate + CoA + H(+) => (9Z,12Z)-octadecadienoyl-CoA + H2O


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-(4R)-hydroxysphinganine = (4R)-hydroxysphinganine + (5Z,8Z,11Z,14Z)-eicosatetraenoate


name: CXXC1 and WDR82 bind SET1B complex (Schizosaccharomyces pombe)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Drosophila melanogaster)


name: SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: Removal of miRNA passenger strand (Canis familiaris)


name: ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate => ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate


name: Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Mus musculus)


name: 2-(9Z-octadecenoyl)-glycerol + eicosanoyl-CoA = 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: (2E)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in) => (E)-hexadec-2-enoate(out) + ATP(in) + CoA(in) + H(+)(out)


name: (E)-coniferol + NADP(+) <=> (E)-coniferaldehyde + H(+) + NADPH


name: Caspase-mediated cleavage of Desmoglein 2 (Mus musculus)


name: (6R)-10-formyltetrahydrofolate + H2O + NADP(+) <=> (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH


name: mRNA2 is translated to Spike (Homo sapiens)


name: D-xylulose 1,5-bisphosphate + H2O => D-xylulose 5-phosphate + phosphate


name: CLN3 transports GalCer to plasma membrane (Caenorhabditis elegans)


name: 4-chlorophenylacetonitrile + 2 H2O => 4-chlorophenylacetate + NH4(+)


name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Homo sapiens)


name: XPO1 binds the beta-catenin:CBY complex (Bos taurus)


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Drosophila melanogaster)


name: USP8 deubiquitinates STAM2:HGS (Homo sapiens)


name: H(+) + menaquinone-8 + NADPH <=> menaquinol-8 + NADP(+)


name: 2,4,5-trichlorocyclohexa-2,5-dien-1-ol + H2O = 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + chloride + H(+)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Rattus norvegicus)


name: FUT3 transfers Fuc to Type 1 MSGG to form sLeA (Drosophila melanogaster)


name: E1 mediated ubiquitin activation (Sus scrofa)


name: RUNX1 binds PRC1 complexes (Drosophila melanogaster)


name: PAK1 binds ARHGEF6 (Drosophila melanogaster)


name: GREB1 translation is negatively regulated by miR-26A and B (Homo sapiens)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Bos taurus)


name: carbofuran + H(+) + H2O => 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol + CO2 + methylamine


name: PapA5 transforms mycocerosyl to PDIM (Mycobacterium tuberculosis)


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Schizosaccharomyces pombe)


name: Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Homo sapiens)


name: Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Sus scrofa)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Plasmodium falciparum)


name: lipid A phosphate methyltransferase activity


name: ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB (Canis familiaris)


name: acetyl-CoA + L-histidine <=> CoA + H(+) + N(alpha)-acetyl-L-histidine