name: acetyl-CoA + N-terminal L-aspartyl-L-aspartyl-L-aspartyl-[protein] => CoA + H(+) + N-terminal N-acetyl-L-aspartyl-L-aspartyl-L-aspartyl-[protein]


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate => 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: PPM1A dephosphorylates nuclear SMAD2/3 (Sus scrofa)


name: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) => (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP => an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose


name: Reduction of disulphide bonds in MHC II antigens (Bos taurus)


name: BORA binds PLK1 and AURKA (Xenopus tropicalis)


name: DMBT1 binds SFTPD 12mer, SFTPAs (Bos taurus)


name: GDIs block activation of RHOA (Canis familiaris)


name: a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose <=> 1,2-diacyl-3-O-[alpha-D-glucosyl-(1-> 2)-alpha-D-glucosyl]-sn-glycerol + H(+) + UDP


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)


name: a 5'-end triphospho-(purine-ribonucleoside) in mRNA + GDP + H(+) = a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + diphosphate


name: chondroitin 4'-sulfate = dermatan 4'-sulfate


name: Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA (Bos taurus)


name: Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) (Homo sapiens)


name: 2-oxoglutarate + L-aspartyl-[protein] + O2 => (3S)-3-hydroxy-L-aspartyl-[protein] + CO2 + succinate


name: all-trans-retinyl tetradecanoate + CoA => all-trans-retinol + tetradecanoyl-CoA


name: (R)-carnitine(in) + glycine betaine(out) <=> (R)-carnitine(out) + glycine betaine(in)


name: H(+) + 2 monodehydro-L-ascorbate radical + NADH <=> 2 L-ascorbate + NAD(+)


name: a ganglioside GT3 + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GT2 + H(+) + UDP


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Mus musculus)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Bos taurus)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Schizosaccharomyces pombe)


name: PAK1-3 autophosphorylates (Homo sapiens)


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Homo sapiens)


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Canis familiaris)


name: a ganglioside GP1c (d18:1(4E)) + H2O => a ganglioside GQ1c (d18:1(4E)) + N-acetylneuraminate


name: AMOT proteins bind WWTR1 (TAZ) (Xenopus tropicalis)


name: a carboxylate(out) + nicotinate(in) <=> a carboxylate(in) + nicotinate(out)


name: Binding of calnexin/calreticulin to the unfolded protein (Homo sapiens)


name: Keratin tetramers bind to form unit length filaments (Canis familiaris)


name: Exocytosis of secretory granule lumen proteins (Bos taurus)


name: a ganglioside GT1b (d18:1(4E)) + N-acetylneuraminate => a ganglioside GQ1b (d18:1(4E)) + H2O


name: (3R)-hydroxyhexanoyl-CoA + NAD(+) => 3-oxohexanoyl-CoA + H(+) + NADH


name: 9-cis-4-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 9-cis-4-oxoretinoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate <=> (+)-aristolochene + diphosphate


name: Active ARF recruits coatomer (Schizosaccharomyces pombe)


name: CHL1 interacts with Ankyrin-G (Homo sapiens)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Mus musculus)


name: hexadecanoyl-CoA + N-terminal glycyl-[protein] = CoA + H(+) + N-terminal N(6)-hexadecanoylglycyl-[protein]


name: Activated calmodulin binds ADCY1,ADCY8 (Homo sapiens)


name: uridine(35) in tRNA(Tyr) => pseudouridine(35) in tRNA(Tyr)


name: 4 CO2 + 4 CoA + dihydropinosylvin => 3-phenylpropanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: NQO2:FAD dimer reduces quinones to hydroquinones (Bos taurus)


name: (2S,3S)-2-methylcitrate <=> 2-methyl-trans-aconitate + H2O


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Mus musculus)


name: a 2-acylglycerol + ATP = a 2-acyl-sn-glycerol 3-phosphate + ADP + H(+)


name: (2S)-2-hydroxyphytanate + O2 <=> 2-oxophytanate + H2O2


name: (cis-prenyl)n-diphosphate + isopentenyl diphosphate = (cis-prenyl)(n+1)-diphosphate + diphosphate


name: MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Canis familiaris)


name: ALOX5 is phosphorylated by MAPKAP2 (Mus musculus)


name: H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Canis familiaris)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Sus scrofa)


name: H2O + monoacyl-sn-glycero-3-phosphate <=> a monoacylglycerol + phosphate


name: 1-phospho-alpha-D-glucuronate + H(+) + UTP <=> diphosphate + UDP-alpha-D-glucuronate


name: SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Bos taurus)


name: PDCL promotes G-protein beta 5 folding (Caenorhabditis elegans)


name: indolepyruvate ferredoxin oxidoreductase activity


name: Trans-homophilic interaction of PECAM-1 (Homo sapiens)


name: 2 H(+) + triphosphate => H2O + trimetaphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)


name: 5-hydroxythiophene-2-carbonyl-CoA + H2O <=> 4-carboxy-2-thioxobutanoyl-CoA


name: acetone + H(+) + NADPH + O2 = H2O + methyl acetate + NADP(+)


name: "acetone monooxygenase (methyl acetate-forming)"


name: 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Homo sapiens)


name: chloride(out) + Cs(+)(in) + 2 hydrogencarbonate(in) => chloride(in) + Cs(+)(out) + 2 hydrogencarbonate(out)


name: PDGFR mutants bind type I TKIs (Homo sapiens)


name: carboxyspermidine + H2O + NADP(+) => H(+) + L-aspartate 4-semialdehyde + NADPH + putrescine


name: MATEs mediate extrusion of xenobiotics (Homo sapiens)


name: Collagen type VII binds integrin alpha2beta1 (Mus musculus)


name: alizarin + UDP-alpha-D-glucose <=> 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP


name: ATP + L-aspartate => 4-phospho-L-aspartate + ADP


name: chloride(out) + D-methionine(out) + 2 Na(+)(out) => chloride(in) + D-methionine(in) + 2 Na(+)(in)


name: Mitochondrial recruitment of Drp1 (Schizosaccharomyces pombe)


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O => a 1-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Saccharomyces cerevisiae)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Sus scrofa)


name: 2-oxoglutarate + L-hyoscyamine + O2 <=> (6S)-6-hydroxyhyoscyamine + CO2 + succinate


name: [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine => [phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine


name: a (3R)-2'-hydroxyisoflavanone + H(+) + NADPH => a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+)


name: (8Z,11Z,14Z)-eicosatrienoate + 2 O2 => prostaglandin G1


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + H2O = 1-O-hexadecyl-sn-glycerol + acetate + H(+)


name: 19-(4-hydroxyphenyl)nonadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Canis familiaris)


name: H(+) + hexadecanoyl-CoA + malonyl-CoA = 3-oxooctadecanoyl-CoA + CO2 + CoA


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Schizosaccharomyces pombe)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Rattus norvegicus)


name: (9Z)-octadecenoate + 1-hexadecanoylglycerone 3-phosphate = 1-(9Z)-octadecenoylglycerone 3-phosphate + hexadecanoate


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Bos taurus)


name: MVB Vesicle Formation (Caenorhabditis elegans)


name: 2',3'-cGAMP(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) => 2',3'-cGAMP(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: 3''-dehydropuerarin => 1,5-anhydro-D-erythro-hex-1-en-3-ulose + daidzein


name: Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B (Bos taurus)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Dictyostelium discoideum)


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Mus musculus)


name: NOX4, NOX5 reduce O2 to O2.- (Mus musculus)


name: "mannan-binding lectin-associated serine protease-2"


name: PPA2A dephosphorylates SPRY2 (Sus scrofa)


name: 9 CO2 + 10 CoA + 7 H2O + 13 NADP(+) + S-adenosyl-L-homocysteine + soppiline A => acetyl-CoA + 20 H(+) + 9 malonyl-CoA + 13 NADPH + S-adenosyl-L-methionine


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Bos taurus)


name: dimethylallyl diphosphate + 2 isopentenyl diphosphate <=> (2Z,6Z)-farnesyl diphosphate + 2 diphosphate


name: D-ribulose 1-phosphate => dihydroxyacetone phosphate + glycolaldehyde


name: ASPG hydrolyses L-Asn to L-Asp (Mus musculus)


name: IMP + methylamine => H(+) + H2O + N(6)-methyl-AMP


name: a D-alpha-amino acid + a quinone + H2O = a 2-oxocarboxylate + a quinol + NH4(+)


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Saccharomyces cerevisiae)


name: (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) = (2Z,4Z)-2-hydroxyhepta-2,4-diene-1,7-dioate + CO2


name: ARFGAPs stimulate ARF GTPase activity (Dictyostelium discoideum)


name: beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = D-glucose + sphing-4-enine


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Canis familiaris)


name: CDC42 GDIs block activation of CDC42 (Homo sapiens)


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Danio rerio)


name: [eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Canis familiaris)


name: (2E)-2-hydroxypenta-2,4-dienoate + anthranilate + H(+) => (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Dictyostelium discoideum)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Sus scrofa)


name: C-13(2)-carboxypyropheophorbide a + methanol => H2O + pheophorbide a


name: POU5F1 (OCT4), SOX2, NANOG, KLF4, PBX1, SMAD2 bind the NANOG promoter (Homo sapiens)


name: H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol = a fatty acid + H(+) + long chain acyl-3-O-beta-D-galactosyl-sn-glycerol


name: H2O + UDP-2,3-diacyl-alpha-D-glucosamine <=> 2,3-diacyl-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP


name: cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity


name: CUBN dissociates from 25(OH)D (Caenorhabditis elegans)


name: (2Z,6Z)-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphate


name: PRODH oxidises L-Pro to 1PYR-5COOH (Drosophila melanogaster)


name: adenosine in double-stranded RNA + H(+) + H2O => inosine in double-stranded RNA + NH4(+)


name: (S)-3-amino-3-phenylpropanoate + 2-oxoglutarate <=> 3-oxo-3-phenylpropanoate + L-glutamate


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Rattus norvegicus)


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Bos taurus)


name: galactitol + NAD(+) => H(+) + keto-L-tagatose + NADH


name: Conversion of Glycerol to Glycerol-3-phosphate (Homo sapiens)


name: RHOD binds effectors at the Golgi membrane (Rattus norvegicus)


name: PTPN11 is phosphorylated (Canis familiaris)


name: ORC6 binds KPNA1 or KPNA6 (Xenopus tropicalis)


name: Caspase-mediated cleavage of Lamin A (Rattus norvegicus)


name: 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine => 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: SRD5A2 binds SRD5A2 inhibitors (Caenorhabditis elegans)


name: 4-methyl-2-oxopentanoate(out) + H(+)(out) <=> 4-methyl-2-oxopentanoate(in) + H(+)(in)


name: 2'-deamino-2'-hydroxyparomamine + H(+) + UDP => 2-deoxystreptamine + UDP-alpha-D-glucose


name: Uncleaved Pink1 accumulates in damaged mitochondria (Caenorhabditis elegans)


name: Active G alpha (q) binds RGS proteins (Mus musculus)


name: CO2 + serotonin => 5-hydroxy-L-tryptophan + H(+)


name: 2xTPK1:Mg2+ phosphorylates THMN (Dictyostelium discoideum)


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Mus musculus)


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Sus scrofa)


name: 3-hydroxy-L-kynurenine + S-adenosyl-L-methionine => 3-hydroxy-4-methyl-L-kynurenine + H(+) + S-adenosyl-L-homocysteine


name: phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate (Saccharomyces cerevisiae)


name: (S)-5'-oxoaverantin + 2 H(+) + NADH => (1'S,5'R)-5'-hydroxyaverantin + NAD(+)


name: Phosphorylated heterodimers of ERBB2 KD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K (Homo sapiens)


name: IRS1 recruits GRB2 to active LTK (Rattus norvegicus)


name: Hydrolysis of Ran:GTP to Ran:GDP (Homo sapiens)


name: SUMOylation of NOP58 with SUMO2 (Xenopus tropicalis)


name: CK2:FACT phosphorylates TP53 (Homo sapiens)


name: D-fructose + phosphate => beta-D-fructose 1-phosphate + H2O


name: catechol + S-adenosyl-L-methionine <=> guaiacol + H(+) + S-adenosyl-L-homocysteine


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Canis familiaris)


name: Formation of the CE:GMP intermediate complex (Schizosaccharomyces pombe)


name: D-arabinose 5-phosphate => D-ribulose 5-phosphate


name: Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: C3G stimulates nucleotide exchange on Rap1 (Canis familiaris)


name: Free APC/C phosphorylated by Plk1 (Gallus gallus)


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Sus scrofa)


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Sus scrofa)


name: H(+) + 2 methylcob(III)alamin-[methionine synthase] + NADP(+) + 2 S-adenosyl-L-homocysteine = 2 cob(II)alamin-[methionine synthase] + NADPH + 2 S-adenosyl-L-methionine


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 7-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + isochorismate + L-glutamate => AMP + diphosphate + H(+) + isochorismoyl-L-glutamate


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Mus musculus)


name: ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Saccharomyces cerevisiae)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H(+) + 3 NADH + 3 O2 <=> 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 4 H2O + 3 NAD(+)


name: demethylspheroidene + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + spheroidene


name: L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-glucosyl-L-tyrosyl-[glycogenin] + H(+) + UDP


name: cytidine(48) in tRNA precursor + S-adenosyl-L-methionine => 5-methylcytidine(48) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexanoyl-CoA = 1-hexadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + CoA


name: a fatty acid(in) + ATP + H2O = a fatty acid(out) + ADP + H(+) + phosphate


name: Photons induce isomerization of 11c-retinyl to at-retinyl (Rattus norvegicus)


name: UDP-alpha-D-glucose(in) + UMP(out) <=> UDP-alpha-D-glucose(out) + UMP(in)


name: H2O + L-arabino-1,4-lactone 5-phosphate <=> 5-phospho-L-arabinonate + H(+)


name: 8 CO2 + 9 CoA + 7 H2O + 13 NADP(+) + wortmanamide B => 5-aminopentanoate + acetyl-CoA + 20 H(+) + 8 malonyl-CoA + 13 NADPH


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Mus musculus)


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Caenorhabditis elegans)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Bos taurus)


name: 4-O-(beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + H2O <=> 4-O-(beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose


name: 9,10-epoxyoctadecanoate + H2O = 9,10-dihydroxyoctadecanoate


name: Hydrolysis of PC to PA by PLD (Dictyostelium discoideum)


name: O2 + prostaglandin I2 + reduced [NADPH--hemoprotein reductase] => 19-hydroxy-prostaglandin I2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: monocyclic sesterterpenediol synthase activity


name: CoA + O-heptanoyl-L-seryl-[protein] => heptanoyl-CoA + L-seryl-[protein]


name: (2S)-dihydrotricetin + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: RUNX2 binds SMAD1 in the nucleus (Homo sapiens)


name: Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + H(+) + H2O <=> Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine] + N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine


name: PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Bos taurus)


name: AR binds AR antagonists (Canis familiaris)


name: 3-oxo-(13Z)-eicosenoyl-CoA + H(+) + NADPH = (R)-3-hydroxy-(13Z)-eicosenoyl-CoA + NADP(+)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Xenopus tropicalis)


name: (20S)-ginsenoside Rb1 + H(+) + UDP => (20S)-ginsenoside Rd + UDP-alpha-D-glucose


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Mus musculus)


name: Dopa is oxidized to dopaquinone by TYR (Canis familiaris)


name: N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Canis familiaris)


name: DBI, ACBD7 bind MCFA-CoA and LCFA-CoA (Plasmodium falciparum)


name: 4-aminobutanoate + glyoxylate <=> glycine + succinate semialdehyde


name: NEIL1 cleaves DHU from damaged DNA (Sus scrofa)


name: Dephosphorylation of STAT1 by SHP2 (Bos taurus)


name: uridine(54) in tRNA => pseudouridine(54) in tRNA


name: HuR:mRNA complex translocates from the nucleus to the cytosol (Sus scrofa)


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Bos taurus)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Caenorhabditis elegans)


name: alpha-D-mannosyl-(1->3)-alpha-D-galactosyl-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+) => alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose


name: 3-methylbutanoyl-CoA + H2O = 3-methylbutanoate + CoA + H(+)


name: acetoin + aldehydo-D-ribose 5-phosphate <=> 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde


name: 5-(carboxyamino)imidazole ribonucleotide mutase activity


name: 2-oxoglutarate + L-arogenate => L-glutamate + prephenate


name: 3-phosphooxypyruvate + H(+) + NADH => (2R)-3-phosphoglycerate + NAD(+)


name: 2,3-epoxyphylloquinone + 4-carboxy-L-glutamyl-[protein] + H(+) + H2O <=> CO2 + L-glutamyl-[protein] + O2 + phylloquinol


name: UGT1A3 lactonizes ATV to ATVL (Mus musculus)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Homo sapiens)


name: factor XII -> factor XIIa (Xenopus tropicalis)


name: 3-hydroxy-4-methyl-L-kynurenine + H2O <=> 3-hydroxy-4-methylanthranilate + H(+) + L-alanine


name: mRNA1 is translated to pp1a (Homo sapiens)


name: TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Homo sapiens)


name: COASY transfers an adenylyl group from ATP to PPANT (Xenopus tropicalis)


name: dIMP + H2O = 2-deoxy-D-ribose 5-phosphate + hypoxanthine


name: small conductance calcium-activated potassium channel inhibitor activity


name: Degradation of ubiquitinated SKI/SKIL (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + tauro-alpha-muricholate => adenosine 3',5'-bisphosphate + H(+) + tauro-alpha-muricholate 7-sulfate


name: PIAS1 SUMOylates SATB1 with SUMO1 (Caenorhabditis elegans)


name: Cleavage and polyadenylation of Intronless Pre-mRNA (Gallus gallus)


name: DLD dimer dehydrogenates dihydrolipoyl (Caenorhabditis elegans)


name: CCA tRNA nucleotidyltransferase activity


name: L-aspartate(in) + L-tryptophan(out) => L-aspartate(out) + L-tryptophan(in)


name: Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers (Homo sapiens)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Dictyostelium discoideum)


name: VAV1 is a GEF for Rho/Rac family GTPases (Rattus norvegicus)


name: Interaction of Tie2 with Ang1 (Danio rerio)


name: NAD(+) + pyridoxal <=> 4-pyridoxolactone + H(+) + NADH


name: 2-oxoglutaramate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + L-glutamine


name: H(+) + NADPH + prostaglandin D2-ethanolamide = 11beta-prostaglandin F2-ethanolamide + NADP(+)


name: OAT2 and OAT4 mediate transport of sulphate conjugates (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + hexadecanoate


name: N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Drosophila melanogaster)


name: N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) <=> 5alpha-pregnane-3,20-dione + H(+) + NADPH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: 3-hydroxyoctadecanoyl-CoA + NADP(+) => 3-oxooctadecanoyl-CoA + H(+) + NADPH


name: NTRK2-activated PI3K generates PIP3 (Homo sapiens)


name: PDPK1 phosphorylates SGK1 (Saccharomyces cerevisiae)


name: an acyl-CoA + L-lysyl-[protein] <=> CoA + H(+) + N(6)-acyl-L-lysyl-[protein]


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Schizosaccharomyces pombe)


name: D-glycero-D-manno-heptose 1,7-bisphosphate + H2O => D-glycero-D-manno-heptose 1-phosphate + phosphate


name: H2O + tetradecanoyl-[ACP] => H(+) + holo-[ACP] + tetradecanoate


name: OCT3 mediates renal uptake of organic cations (Bos taurus)


name: 2-acyl LPG is acylated to PG by LPGAT (Saccharomyces cerevisiae)


name: NRXNs bind CASK:Protein 4.1 (Sus scrofa)


name: (S)-homoeriodictyol + H(+) + S-adenosyl-L-homocysteine => (S)-eriodictyol + S-adenosyl-L-methionine


name: (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Rattus norvegicus)


name: 2 Na(+)(out) + phosphate(out) => 2 Na(+)(in) + phosphate(in)


name: chloride(out) + 2 hydrogencarbonate(in) <=> chloride(in) + 2 hydrogencarbonate(out)


name: fluoroacetaldehyde + L-threonine => 4-fluoro-L-threonine + acetaldehyde


name: TRAF6 is K63 poly-ubiquitinated (Canis familiaris)


name: [L-4-(L-arginin-2-N-yl)aspartate](n) + H2O => [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate


name: Insertion of correct bases opposite the lesion by POLH (Mus musculus)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Canis familiaris)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Dictyostelium discoideum)


name: Oligomerization of BAX at the mitochondrial membrane (Sus scrofa)


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Mus musculus)


name: (2E)-geranyl diphosphate => beta-pinene + diphosphate


name: Phosphorylation of MDM4 by CHEK2 (Rattus norvegicus)


name: a 14alpha-formyl steroid + O2 + reduced [NADPH--hemoprotein reductase] = a Delta(14) steroid + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Tachykinin receptor 1 (NK1) binds to substance P (Homo sapiens)


name: RBX1:CUL3 dissociates from forming autophagosome (Sus scrofa)


name: AP1G2 binds HGS and CHMP2A (Mus musculus)


name: UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG (Bos taurus)


name: a ganglioside GQ1c + H2O => a ganglioside GT1c + N-acetylneuraminate


name: glutarate(in) + succinate(out) = glutarate(out) + succinate(in)


name: H(+) + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP => N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine


name: (22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity


name: SUMOylation of RAD52 with SUMO1 (Bos taurus)


name: 2-phenylsuccinyl-CoA + succinate => phenylsuccinate + succinyl-CoA


name: Kinesin-1 is a heterotetramer (Drosophila melanogaster)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) + H2O <=> 1-O-alkyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + phosphate


name: 3,6-dichloropyridine-2,5-diol + FADH2 + O2 => 6-chloro-3-hydroxypyridine-2,5-dione + chloride + FAD + 2 H(+) + H2O


name: CO2 + L-aspartate + NH4(+) => 2 H(+) + H2O + N-carbamoyl-L-aspartate


name: (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+) => (2R,3R)-dihydroquercetin + H(+) + NADPH + O2


name: PTK6 binds AKT1 (Caenorhabditis elegans)


name: MDM2 translocates to the cytosol (Rattus norvegicus)


name: L-lysyl-[lipoyl-carrier protein] + N(6)-octanoyl-L-lysyl-[glycine-cleavage complex H protein] <=> L-lysyl-[glycine-cleavage complex H protein] + N(6)-octanoyl-L-lysyl-[lipoyl-carrier protein]


name: (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H(+) + NADPH <=> (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: 3-oxocholan-24-oyl-CoA + H(+) + NADH => lithocholoyl-CoA + NAD(+)


name: Activated FGFR4 phosphorylates SHC1 (Caenorhabditis elegans)


name: 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol


name: CYP8B1 12-hydroxylates 4CHOL7a,27DONE (Xenopus tropicalis)


name: 6-hydroxyphenazine-1-carboxylate + 2 H(+) + NADH + O2 => 1,6-dihydroxyphenazine + CO2 + H2O + NAD(+)


name: DCD peptide binds bacterial membrane phospholipids (Homo sapiens)


name: 2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine + H2O <=> H(+) + prostaglandin E2 + sn-glycero-3-phosphoethanolamine


name: NTPDase2 hydrolyzes nucleoside triphosphates (Danio rerio)


name: acetyl-CoA + 2 AH2 + 9 H(+) + malate + 6 malonyl-CoA + 5 NADPH + 2 S-adenosyl-L-methionine = 2 A + 6 CO2 + 7 CoA + 6 H2O + 5 NADP(+) + 2 S-adenosyl-L-homocysteine + trihazone A


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: STING binds cyclic GMP-AMP (Gallus gallus)


name: Phosphorylation of Cdh1 by Cyclin B1:Cdc2 (Homo sapiens)


name: H2O + tetradecanoyl-CoA <=> CoA + H(+) + tetradecanoate


name: D-glucuronate(out) + H(+)(out) = D-glucuronate(in) + H(+)(in)


name: Factor B binds to surface-associated C3b (Danio rerio)


name: NRXNs binds CASK tripartite complex (Homo sapiens)


name: aceneuramate = N-acetyl-D-mannosamine + pyruvate


name: D-glucose 6-phosphate <=> 1D-myo-inositol 3-phosphate


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)


name: ETA is phosphorylated to PETA by CHK/ETNK (Plasmodium falciparum)


name: 1-propanol + NAD(+) <=> H(+) + NADH + propanal


name: PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release (Gallus gallus)


name: 3'-phosphoadenylyl sulfate + alpha,alpha-trehalose => 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+)


name: NTRK2-phosphorylated FRS2 binds GRB2 (Sus scrofa)


name: (2E)-geranyl diphosphate <=> beta-thujene + diphosphate


name: 2'-deoxycytidine(in) + H(+)(in) <=> 2'-deoxycytidine(out) + H(+)(out)


name: cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Schizosaccharomyces pombe)


name: H2O + limonene 1,2-epoxide = limonene-1,2-diol


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Mus musculus)


name: (9Z)-octadecenoate + L-lysine => H2O + N-(9Z-octadecenoyl)-L-lysine


name: butyrolactone II + dimethylallyl diphosphate <=> butyrolactone I + diphosphate


name: 4-hydroxyestrone + O2 => (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+)


name: 6-trans-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-6-trans-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + L-serine + NAD(+) => 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: CD28 homodimer binds B7-1 homodimer (Rattus norvegicus)


name: (E)-4-coumaroyl-CoA + H2O => (R)-3-(4-hydroxyphenyl)lactoyl-CoA


name: H(+) + NADH + phylloquinone => NAD(+) + phylloquinol


name: chenodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP => chenodeoxycholate + UDP-alpha-D-glucuronate


name: chloride(out) + formate(in) = chloride(in) + formate(out)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[11-hydroxy-(9Z)-octadecenoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + mature tRNA + nicotinamide => 2'-phospho-[ligated tRNA] + NAD(+)


name: Autocatalytic activation of bound proMMP2 (Drosophila melanogaster)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Gallus gallus)


name: CNIH2,3 bind GRIA1 (Drosophila melanogaster)


name: 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide => beta-nicotinamide D-ribonucleotide + diphosphate


name: [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + CO2 + succinate => 2-oxoglutarate + [ribosomal protein uS12]-L-proline + O2


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Canis familiaris)


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Mus musculus)


name: VEGFA-165 dimer binds VEGFA inhibitors (Xenopus tropicalis)


name: a D-alpha-amino acid + a quinone + H2O <=> a 2-oxocarboxylate + a quinol + NH4(+)


name: H2O + O-phospho-L-seryl-[myosin light chain] <=> L-seryl-[myosin light chain] + phosphate


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Bos taurus)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Dictyostelium discoideum)


name: ERBB3 binds RNF41 ubiquitin ligase (Danio rerio)


name: L,L-cystathionine <=> 2-aminobut-2-enoate + L-cysteine


name: aromatic amino acid:proton symporter activity


name: Ubiquitination of phospho-p27/p21 (Sus scrofa)


name: diisopropyl fluorophosphate + H2O <=> diisopropyl phosphate + fluoride + 2 H(+)


name: AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Rattus norvegicus)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Danio rerio)


name: ATP + H2O + L-isoleucine(out) <=> ADP + H(+) + L-isoleucine(in) + phosphate


name: USP24 deubiquitinates DDB2 (Mus musculus)


name: HRH1 binds HRH1 inverse agonists (Gallus gallus)


name: CO binds to free ferrohemoglobin (Canis familiaris)


name: D-alanine + L-glutamine <=> gamma-L-glutamyl-D-alanine + NH4(+)


name: (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] <=> 13-hydroxy-alpha-tocopherol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: sporulenol <=> (R)-tetraprenyl-beta-curcumene + H2O


name: "Activator" RAF:YWHAB dimer binds RAS:GTP (Gallus gallus)


name: ferric triacetylfusarinine C:proton symporter activity


name: cholesterol + PAPS => cholesterol sulfate + PAP (Homo sapiens)


name: 2 (3R)-hydroxydecanoyl-[ACP] + H2O <=> (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + H(+) + 2 holo-[ACP]


name: MHC class II antigen processing (Caenorhabditis elegans)


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Homo sapiens)


name: N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate => H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH


name: B4GALTs transfer Gal to the keratan chain (Canis familiaris)


name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Saccharomyces cerevisiae)


name: OTULIN,USP5 cleaves UBB yielding ubiquitin (Canis familiaris)


name: butanoyl-CoA + H(+) + malonyl-[ACP] => 3-oxohexanoyl-[ACP] + CO2 + CoA


name: Cathelicidin LL-37 binds to bacterial cell wall (Mus musculus)


name: hexadecanoyl-[ACP] + sn-glycerol 3-phosphate = 1-hexadecanoyl-sn-glycero-3-phosphate + holo-[ACP]


name: 3-O-methylmyricetin + H(+) + S-adenosyl-L-homocysteine => myricetin + S-adenosyl-L-methionine


name: p62 binds ubiquitinated mitochondrial substrates (Gallus gallus)


name: DHNTP is dephosphorylated by PTPS to PTHP (Homo sapiens)


name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid (Homo sapiens)


name: Internalization of ubiquitinated FLT3 (Mus musculus)


name: an hexadecanoyl-acylglycerol + CoA => a 1-acylglycerol + hexadecanoyl-CoA


name: Unknown kinase phosphorylates RBV-MP (Homo sapiens)


name: (S)-lactate(in) + H(+)(in) => (S)-lactate(out) + H(+)(out)


name: NADP(+) + octadecan-1-ol => H(+) + NADPH + octadecanal


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Gallus gallus)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate = (+)-aristolochene + diphosphate


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Mus musculus)


name: VLDL translocates from SER lumen to extracellular region (Homo sapiens)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Sus scrofa)


name: Caspase-mediated cleavage of MASK (Homo sapiens)


name: PE is hydrolyzed to 2-acyl LPE by PLA2G4C (Rattus norvegicus)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Canis familiaris)


name: 15-methylhexadecasphinganine 1-phosphate => 13-methyltetradecanal + phosphoethanolamine


name: a menaquinol + 2 O2 <=> a menaquinone + 2 H(+) + 2 superoxide


name: H2O + L-saccharopine + O2 <=> (S)-2-amino-6-oxohexanoate + H2O2 + L-glutamate


name: Formation of NR-MED1 Coactivator Complex (Xenopus tropicalis)


name: 4-coumaroyl-CoA + S-adenosyl-L-methionine = CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine


name: Extracellular domains of STAN bind to each other in adjacent cells (Drosophila melanogaster)


name: acetyl-CoA + octadecanoyl-CoA = 3-oxoeicosanoyl-CoA + CoA


name: decanoyl-CoA + phytol <=> CoA + decanoate phytyl ester


name: fumitremorgin C + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin A


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Homo sapiens)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Rattus norvegicus)


name: NTRK2 phosphorylates FRS3 (Homo sapiens)


name: 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH => 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: Ferriheme is transferred from Methemoglobin to Hemopexin (Sus scrofa)


name: alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate


name: beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)


name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Bos taurus)


name: misfolded CFTR is degraded by the 26S proteasome (Sus scrofa)


name: GDP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosamine => GDP-beta-L-fucose + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Sus scrofa)


name: carnitine + CO2 + succinate => 2-oxoglutarate + 4-(trimethylamino)butanoate + O2


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)


name: SRD5A3 dehydrogenates TEST to DHTEST (Danio rerio)


name: H(+)(out) + L-alanyl-D-glutamate(out) => H(+)(in) + L-alanyl-D-glutamate(in)


name: NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = H(+) + NADH + UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose


name: (2E)-butenoyl-CoA + (R)-carnitine = CoA + O-(2E)-butenoyl-(R)-carnitine


name: 2 7-demethylsiderin + NADPH + O2 => desertorin A + 2 H2O + NADP(+)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Bos taurus)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Rattus norvegicus)


name: PI is hydrolyzed to 2-acyl LPI by PLA2[13] (Canis familiaris)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Drosophila melanogaster)


name: an adenosine in mRNA + CO2 + formaldehyde + succinate => 2-oxoglutarate + an N(1)-methyladenosine in mRNA + O2


name: 2 H(+) + O2 + octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] <=> (9Z)-octadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 15-oxoprostaglandin E1 + H(+) + NADPH => 13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+)


name: malonyl-[ACP] + S-adenosyl-L-methionine => malonyl-[ACP] methyl ester + S-adenosyl-L-homocysteine


name: Syndecan-1 binds fibronectin (Bos taurus)


name: 5 (S)-methylmalonyl-CoA + a medium-chain fatty acyl-CoA + 32 H(+) + 5 malonyl-CoA + 22 NADPH => a mycoketide-CoA + 10 CO2 + 10 CoA + 11 H2O + 22 NADP(+)


name: 4 AH2 + sn-3-O-(geranylgeranyl)glycerol 1-phosphate => 4 A + sn-3-O-phytanylglycerol 1-phosphate


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Schizosaccharomyces pombe)


name: ATM phosphorylates DYRK2 (Gallus gallus)


name: 2 9-riburonosylhypoxanthine + 2 H(+) => 2 5'-dehydroinosine + O2


name: 2 H(+) + O2 + octane + 2 reduced [rubredoxin] = H2O + octan-1-ol + 2 oxidized [rubredoxin]


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Mus musculus)


name: a (2R,3R)-flavan-3-ol + 2 NADP(+) <=> an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)


name: HSBP1 oligomer binds ESRs (Homo sapiens)


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Gallus gallus)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Mus musculus)


name: PP2A dephosphorylates BANF1 (Drosophila melanogaster)


name: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: AH2 + H(+) + 3 malonyl-CoA + propanoyl-CoA + 2 S-adenosyl-L-methionine <=> 2-ethyl-4,6-dihydroxy-3,5-dimethylbenzaldehyde + A + 3 CO2 + 4 CoA + H2O + 2 S-adenosyl-L-homocysteine


name: L-methionine <=> 2-aminobut-2-enoate + methanethiol


name: glyoxal + L-arginyl-[protein] => N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein]


name: H2O + N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine = L-asparagine + N-acetyl-D-glucosamine


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Xenopus tropicalis)


name: tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent


name: cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine <=> 5-methylcytidine(72) in tRNA(Thr) + H(+) + S-adenosyl-L-homocysteine


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Bos taurus)


name: USP45 deubiquitinates ERCC1 (Bos taurus)


name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate (Mus musculus)


name: cytidine(8) in tRNA + H(+) + H2O => NH4(+) + uridine(8) in tRNA


name: voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Caenorhabditis elegans)


name: DEGS2 oxygenates dihydroceramide (Canis familiaris)


name: beta-myrcene + O2 + reduced [NADPH--hemoprotein reductase] => (4R)-ipsdienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation Of Bloc-1 Complex (Bos taurus)


name: a carboxylate + H(+) + pyruvate => a 3-acylpyruvate + H2O


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Rattus norvegicus)


name: ATP + H2O + sulfate(out) => ADP + H(+) + phosphate + sulfate(in)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Canis familiaris)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA <=> 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Homo sapiens)


name: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Rattus norvegicus)


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Homo sapiens)


name: USP8 deubiquitinates RNF128 (Rattus norvegicus)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Homo sapiens)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Canis familiaris)


name: D inhibits WTS (Drosophila melanogaster)


name: a dicarboxylate(in) + urate(out) => a dicarboxylate(out) + urate(in)


name: 3'-phosphoadenylyl sulfate + dopamine <=> adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + H(+)


name: Expression of SMYD1 (BOP) in cardiogenesis (Homo sapiens)


name: alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose


name: BMP2 binds to the receptor complex (Sus scrofa)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Canis familiaris)


name: Phosphorylated PXN recruits the CRK complex (Canis familiaris)


name: 3,4-dihydroxyphenylacetate + FMN + H(+) + H2O => 4-hydroxyphenylacetate + FMNH2 + O2


name: 2-hydroxyethane-1-sulfonate + NAD(+) => H(+) + NADH + sulfoacetaldehyde


name: N,N',N'',N'''-tetraacetylchitotetraose + O2 => H2O2 + N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone


name: REG3A,REG3G binds bacterial peptidoglycan (Sus scrofa)


name: [protein]-disulfide + ADP + phosphate + S-hydroxy-L-cysteinyl-[peroxiredoxin] => [protein]-dithiol + ATP + S-hydroxy-S-oxy-L-cysteinyl-[peroxiredoxin]


name: 5-hydroxyisourate + H2O + NADP(+) => H(+) + NADPH + O2 + urate


name: KPNA2 translocates NBN to the nucleus (Canis familiaris)


name: TRPV1 binds TRPV1 blockers (Drosophila melanogaster)


name: CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus (Bos taurus)


name: CBX5 gene expression is inhibited by E2F6 (Homo sapiens)


name: GDP-alpha-D-mannose + H2O <=> D-mannose + GDP + H(+)


name: H(+) + NADPH + O2 + tigecycline <=> 11a-hydroxytigecycline + H2O + NADP(+)


name: AKT phosphorylates CBY1 (Rattus norvegicus)


name: 8-oxo-GTP + H2O = 8-oxo-GMP + diphosphate + H(+)


name: Interaction of GRB2:SOS complex with p-SHC1 (Homo sapiens)


name: hydrogencarbonate(out) + iodide(in) <=> hydrogencarbonate(in) + iodide(out)


name: NCOA1(868-1441) binds PAX3(1-319) (Bos taurus)


name: Polyubiquitinated NRIF migrates to the nucleus (Homo sapiens)


name: IDUA hydrolyses Heparan sulfate chain(1) (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA => 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: 2 ATP + H(+) = diphosphate + P(1),P(4)-bis(5'-adenosyl) tetraphosphate


name: MDM2 ubiquitinates JMY (Canis familiaris)


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine


name: E2F6 binds the PRC1 complex (Xenopus tropicalis)


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Canis familiaris)


name: O2 + proatranorin I + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin IV


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Gallus gallus)


name: AXL autophosphorylates on Y779 and Y821 (Rattus norvegicus)


name: 28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA (Homo sapiens)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Canis familiaris)


name: Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide => Ni(2+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: equisetin + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + trichosetin


name: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine = dihydrochelirubine + H(+) + S-adenosyl-L-homocysteine


name: 1-hydroxy-2-naphthoate + 2 H(+) + NADPH + O2 = CO2 + H2O + NADP(+) + naphthalene-1,2-diol


name: LTD4 is converted to LTE4 by DPEP1/2 (Canis familiaris)


name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Mus musculus)


name: 4',4'-dihydroxyechinenone => canthaxanthin + H2O


name: ADP(in) + FAD(out) <=> ADP(out) + FAD(in)


name: Phosphorylation (Ser5) of RNA pol II CTD (Drosophila melanogaster)


name: GMPS dimer transforms 6TXMP to 6TGMP (Dictyostelium discoideum)


name: H(+) + N-hydroxy-2-acetamidofluorene + NADPH => 2-acetamidofluorene + H2O + NADP(+)


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Bos taurus)


name: NPAS4 stimulates SYT10 gene expression (Homo sapiens)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Drosophila melanogaster)


name: CYP8B1 12-hydroxylates 4CHOL7aOLONE (Canis familiaris)


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Bos taurus)


name: a globoside NOR1 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a globoside NORint (d18:1(4E)) + H(+) + UDP


name: UVSSA:USP7 deubiquitinates ERCC6 (Xenopus tropicalis)


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Drosophila melanogaster)


name: AAMP binds to TBXA2R (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (5Z,8Z,11Z)-eicosatrienoate


name: Binding of TFIIE to the growing preinitiation complex (Caenorhabditis elegans)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Danio rerio)


name: TP53 binds promoters of MIR34 genes (Homo sapiens)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) (Caenorhabditis elegans)


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Caenorhabditis elegans)


name: Mitochondrial recruitment of Drp1 (Canis familiaris)


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Drosophila melanogaster)


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Dictyostelium discoideum)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Canis familiaris)


name: 22-hydroxydocosanoate + NAD(+) <=> 22-oxodocosanoate + H(+) + NADH


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: carbamoyl phosphate + descarbamoylnovobiocin = novobiocin + phosphate


name: MTA is cleaved and phosphorylated (Danio rerio)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Gallus gallus)


name: branched 1,3-beta-D-glucan synthase activity


name: Export of peptide loaded MHC class I complex to PM (Rattus norvegicus)


name: VRK1/VRK2 phosphorylate BANF1 (Rattus norvegicus)


name: acetate + an acyl-CoA => a carboxylate + acetyl-CoA


name: Association of profilin with monomeric actin (Canis familiaris)


name: Activated HOP is autophosphorylated and/or transphosphorylated (Drosophila melanogaster)


name: Trimming of peptides by IRAP in endocytic vesicles (Canis familiaris)


name: hexacosanoyl-CoA + sphinganine => CoA + H(+) + N-hexacosanoylsphinganine


name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (Bos taurus)


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Rattus norvegicus)


name: 5-phosphomethyl-dUMP in DNA + putrescine = 5-N(alpha)-putrescinyl-dTMP in DNA + phosphate


name: FAAH hydrolyses AEA to AA and ETA (Bos taurus)


name: A1 and A3 receptors bind adenosine (Canis familiaris)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Mus musculus)


name: PIAS1,3 SUMOylate ESR1 with SUMO1 (Xenopus tropicalis)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Homo sapiens)


name: SYK is a substrate for JAK1 (Homo sapiens)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Xenopus tropicalis)


name: LONP1 binds mitochondrial inner membrane proteins (Caenorhabditis elegans)


name: (4R)-hydroxy-(6R)-2,2,6-trimethylcyclohexanone + NAD(+) => (6R)-2,2,6-trimethyl-1,4-cyclohexanedione + H(+) + NADH


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O => 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+)


name: 4-(gamma-L-glutamylamino)butanal + H2O + NADP(+) <=> 4-(gamma-L-glutamylamino)butanoate + 2 H(+) + NADPH


name: Translocation of PDK1 to Plasma membrane (Caenorhabditis elegans)


name: 26-hydroxyhexacosanoate + NAD(+) => 26-oxohexacosanoate + H(+) + NADH


name: H2O + wogonin 7-O-beta-D-glucuronate => D-glucuronate + H(+) + wogonin


name: MAPK4,6 translocate to nucleus (Homo sapiens)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Caenorhabditis elegans)


name: agmatine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + N(1)-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine


name: 3 a ubiquinol(in) + 2 H(+)(out) + nitrite(out) => 3 a ubiquinone(in) + 2 H2O(out) + NH4(+)(out)


name: ARSA removes sulfate from SM3 (Homo sapiens)


name: 2-(phosphinatomethylidene)butanedioate + H2O = phosphinomethylisomalate


name: ADP-1-deoxy-1,O(4)-didehydro-D-ribose + L-arginyl-[protein] => ADP-riboxanated L-argininyl-[protein] + H(+) + NH4(+)


name: H(+) + H2O + ladanein + oxidized [NADPH--hemoprotein reductase] => apigenin 4',7-dimethyl ether + O2 + reduced [NADPH--hemoprotein reductase]


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Danio rerio)


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Canis familiaris)


name: PTPN3 binds p-T183,Y185 MAPK12 (Drosophila melanogaster)


name: H2O + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine => a fatty acid + H(+) + N,1-diacyl-sn-glycero-3-phosphoethanolamine


name: PREDL:ALB dissociates (Xenopus tropicalis)


name: ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE (Sus scrofa)


name: phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] = (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit]


name: "C-phycoerythrin alpha-cysteine-82 phycoerythrobilin lyase"


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Mus musculus)


name: an alk-2-enal + H(+) + NADPH => an n-alkanal + NADP(+)


name: PIDD1 associates with CRADD (Bos taurus)


name: LPL hydrolyses TGs from mature CMs (Bos taurus)


name: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester <=> adenosine 3',5'-bisphosphate + H(+) + L-tyrosine methyl ester 4-sulfate


name: SodC reduces superoxide to H2O2 (Homo sapiens)


name: 2'-hydroxybiphenyl-2-sulfinate + FMN + H(+) + H2O + NAD(+) => dibenzothiophene 5,5-dioxide + FMNH2 + NADH + O2


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Mus musculus)


name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Schizosaccharomyces pombe)


name: acetyl-CoA + octan-1-ol = CoA + octyl acetate


name: chloride + H(+) + NH4(+) + pyruvate => 3-chloro-D-alanine + H2O


name: TBK1 phosphorylates STAT6 at Ser407 (Danio rerio)


name: (1R,5R)-beta-pinene + diphosphate => (2E)-geranyl diphosphate


name: DCC interacts with DIP13alpha (Canis familiaris)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)


name: glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 (Bos taurus)


name: Interaction of integrin alphaDbeta2 with fibrin (Mus musculus)


name: Proglucagon translocates from the ER Lumen to secretory granules (Xenopus tropicalis)


name: a ganglioside GM3 + H2O => an N-acyl-sphingoid base + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-nonadioyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: 2-hydroxybutanoate + NADP(+) <=> 2-oxobutanoate + H(+) + NADPH


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2 <=> (2S)-3-phenyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2


name: (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (5Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: RP2:ARL3:GDP:UNC119B dissociates (Homo sapiens)


name: GPX5,6 reduce H2O2 to H2O (Caenorhabditis elegans)


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Bos taurus)


name: AKT1 phosphorylates eNOS (Gallus gallus)


name: 2,4-dihydroxypteridine + NH4(+) => 2-amino-4-hydroxypteridine + H(+) + H2O


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Drosophila melanogaster)


name: Vesicular inhibitory amino acid transport (Rattus norvegicus)


name: 3-ADP-2-phosphoglycerate + H2O => 3-ADP-glycerate + phosphate


name: H(+)(in) + putrescine(in) <=> H(+)(out) + putrescine(out)


name: 2 Na(+)(out) + taurocholate(out) = 2 Na(+)(in) + taurocholate(in)


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Mus musculus)


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Schizosaccharomyces pombe)


name: Rag dimer formation (Saccharomyces cerevisiae)


name: an aromatic primary alcohol + NAD(+) <=> an aromatic aldehyde + H(+) + NADH


name: myricetin + UDP-beta-L-rhamnose => H(+) + myricetin 3-O-alpha-L-rhamnoside + UDP


name: SOAT can transport taurolithocholate-3-sulphate (Caenorhabditis elegans)


name: GPR37L binds prosaposin (Rattus norvegicus)


name: Initial activation of proMMP1 (Caenorhabditis elegans)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Rattus norvegicus)


name: 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA <=> 1-dodecanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Sus scrofa)


name: 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide => H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine


name: D-glucono-1,5-lactone + D-sorbitol => D-fructose + D-glucose


name: H2O + pentanoyl-CoA => CoA + H(+) + pentanoate


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Caenorhabditis elegans)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Drosophila melanogaster)


name: eIF3 and eIF1A bind to the 40S subunit (Rattus norvegicus)


name: AJUBA facilitates AURKA autophosphorylation (Homo sapiens)


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Mus musculus)


name: asc-DeltaC7-CoA + H2O2 => asc-C7-CoA + O2


name: ALDH4A1 oxidises L-GluSS to Glu (Sus scrofa)


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) => 4,5-dihydroxyphthalate + H(+) + NADH


name: 1D-chiro-inositol(out) + 2 Na(+)(out) <=> 1D-chiro-inositol(in) + 2 Na(+)(in)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Homo sapiens)


name: Collagen type XXV ectomain shedding (Mus musculus)


name: SUMOylation of NFKBIA with SUMO1 (Rattus norvegicus)


name: H(+)(in) + L-phenylalanyl-L-phenylalanine(in) => H(+)(out) + L-phenylalanyl-L-phenylalanine(out)


name: a fatty acid + L-lysine => an N-(fatty acyl)-L-lysine + H2O


name: 7-methylxanthosine + H2O <=> 7-methylxanthine + D-ribose + H(+)


name: Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Mus musculus)


name: indole-3-acetaldehyde reductase (NADPH) activity


name: ADP + H(+) + sulfate <=> adenosine 5'-phosphosulfate + phosphate


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Homo sapiens)


name: (S)-3-hydroxybutanoate + 2-oxoglutarate => (R)-2-hydroxyglutarate + acetoacetate


name: Phosphorylated FOXO1A is excluded from the nucleus (Homo sapiens)


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Danio rerio)


name: Caspase mediated cleavage of C-IAP1 (Drosophila melanogaster)


name: CoA + octyl benzoate => benzoyl-CoA + octan-1-ol


name: HTR1A binds HTR1A antagonists (Bos taurus)


name: PDCD1 binds PDCD1 inhibitors (Homo sapiens)


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)


name: D-maltohexaose + H2O <=> alpha-D-glucose + D-maltopentaose


name: (9Z)-tetradecenoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(9Z-tetradecenoyl)-4'-phosphopantetheine


name: Monoubiquitinated PTEN translocates to the nucleus (Dictyostelium discoideum)


name: [HPr protein]-L-serine + diphosphate => [HPr protein]-O-phospho-L-serine + H(+) + phosphate


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA (E. coli) <=> a 2-acyl-sn-glycero-3-phosphocholine + lipid IVB (E. coli)


name: YWHAB dimer dissociates from dephosphorylated RAF (Gallus gallus)


name: CRHR1,CRHR2-1 binds CRH,UCN (Sus scrofa)


name: alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+) => alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose


name: SFTPA/SFTPD binds TLR4:LY96 (Bos taurus)


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Dictyostelium discoideum)


name: (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+) <=> (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H(+) + NADH


name: Inactive G alpha (q) reassociates with G beta:gamma (Xenopus tropicalis)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Canis familiaris)


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein] = a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-lysyl-[protein]


name: Hemoglobin A binds O2, releasing H+ and CO2 (Canis familiaris)


name: H2O2 + pyridine <=> H2O + pyridine N-oxide


name: 3-hydroxyhexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 3,16-dihydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycerol + H(+) + phosphocholine


name: FA anion picks up a proton (Homo sapiens)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Schizosaccharomyces pombe)


name: Degradation of ubiquitinated SMAD2 (Canis familiaris)


name: ALDH3B2 oxidises HXAL to PALM (Dictyostelium discoideum)


name: WWTR1:p-2S-SMAD2,3:SMAD4 binds SERPINE1 gene promoter (Homo sapiens)


name: cholesterol ester + H2O -> cholesterol + fatty acid (Homo sapiens)


name: CO2 + 2 H2O + NADP(+) + violacein => 2 H(+) + NADPH + 2 O2 + protoviolaceinate


name: 1-O-alkyl-sn-glycero-3-phosphate + a fatty acid + H(+) => 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O


name: UBA1 adenylates ubiquitin in the nucleoplasm (Gallus gallus)


name: FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex (Mus musculus)


name: SCF-beta-TrCP ubiquitinylates IkB (Rattus norvegicus)


name: MAP3K5 phosphorylates MKK3 and MKK6 (Homo sapiens)


name: 3beta-hydroxy-5-androstene-7,17-dione + H(+) + NADPH => 3beta,7beta-dihydroxyandrost-5-en-17-one + NADP(+)


name: RNA polymerase III general transcription initiation factor binding


name: MAP2Ks and MAPKs bind to the activated RAF complex (Homo sapiens)


name: NEU2 hydrolyzes Neu5Ac from glycoconjugates (Danio rerio)


name: allodeoxycholoyl-CoA + cholate => allodeoxycholate + choloyl-CoA


name: miR-17 microRNA binds PTEN mRNA (Homo sapiens)


name: PTK6 phosphorylates ARAP1 (Rattus norvegicus)


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Xenopus tropicalis)


name: ADP + H(+) + L-arginyl-L-alpha-amino acid + phosphate => an L-alpha-amino acid + ATP + L-arginine


name: C-ter TLR7 dimer binds imiquimod (Xenopus tropicalis)


name: 2 H(+) + H2O + N-carbamoylsarcosine => CO2 + NH4(+) + sarcosine


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Rattus norvegicus)


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Saccharomyces cerevisiae)


name: H2O + 4 porphobilinogen => hydroxymethylbilane + 4 NH4(+)


name: all-trans-4,4'-diapophytofluene + FAD + H(+) = all-trans-4,4'-diapo-zeta-carotene + FADH2


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Sus scrofa)


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Bos taurus)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate <=> (E,R)-alpha-bisabolene + diphosphate


name: Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) (Homo sapiens)


name: Phosphorylation of IL2RB Y338 enables SHC recruitment (Sus scrofa)


name: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH


name: TGFBR3 translocation to plasma membrane (Rattus norvegicus)


name: a beta-D-glucuronoside + alpha-D-glucose 1-phosphate => a 3-O-beta-D-glucosyl-beta-D-glucuronoside + phosphate


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Plasmodium falciparum)


name: NEU3 cleaves GM3 to form LacCer (plasma membrane) (Bos taurus)


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Xenopus tropicalis)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Bos taurus)


name: H2O + O2 + putrescine => 4-aminobutanal + H2O2 + NH4(+)


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Rattus norvegicus)


name: ESR1:ESTG and EP300 are recruited to TFF3 promoter (Sus scrofa)


name: PKCalpha phosphorylates HuR (Sus scrofa)


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine => diphthine methyl ester-[translation elongation factor 2] + 3 H(+) + 4 S-adenosyl-L-homocysteine


name: Transport of L1 into endosomes (Sus scrofa)


name: 5alpha-dihydrotestosterone sulfate(in) + 2 Na(+)(in) => 5alpha-dihydrotestosterone sulfate(out) + 2 Na(+)(out)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Canis familiaris)


name: Autocatalytic activation of proMMP2 (Bos taurus)


name: Delta(1)-piperideine-2-carboxylate + H2O => 6-amino-2-oxohexanoate


name: a 2'-deoxyribonucleoside + phosphate => a 2'-deoxyribonucleoside 3'-phosphate + H2O


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Homo sapiens)


name: 2 columbamine + O2 <=> 2 berberine + 2 H2O


name: 3-hydroxyhispidin + O2 = (E)-caffeoylpyruvate + CO2 + hnu


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: Dopa is oxidized to dopaquinone by TYR (Homo sapiens)


name: Transport (influx) of bile salts and acids by OATP-A (Sus scrofa)


name: Ribosomal scanning  (Schizosaccharomyces pombe)


name: Dimerized phospho-IRF3 migrates to the nucleus (Mus musculus)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Rattus norvegicus)


name: 4-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate <=> 17beta-estradiol 4-O-(beta-D-glucuronate) + H(+) + UDP


name: H2O + O(6)-methyl-dGTP => diphosphate + H(+) + O(6)-methyl-dGMP


name: Binding of AP1 transcriptional activator complexes to CCND1 promoter (Gallus gallus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Mus musculus)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Mus musculus)


name: a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+) => a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Bos taurus)


name: α1-agonists bind ADRA1A,B,D (Rattus norvegicus)


name: STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Homo sapiens)


name: (13E)-labda-7,13-dien-15-yl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: Src activation following P2Y purinoceptor activation (Homo sapiens)


name: IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Bos taurus)


name: DENND4s exchange GTP for GDP on RAB10 (Xenopus tropicalis)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Dictyostelium discoideum)


name: A + all-trans-3,4-didehydro-13,14-dihydroretinol <=> AH2 + all-trans-3,4-didehydroretinol


name: (R)-3-hydroxybutanoate + [(3R)-hydroxybutanoate](n-1) + H(+) => [(3R)-hydroxybutanoate](n) + H2O


name: bacteriochlorophyll a + 3 NADP(+) => geranylgeranyl-bacteriochlorophyllide a + 3 H(+) + 3 NADPH


name: mycophenolate + UDP-alpha-D-glucuronate => mycophenolic acid O-acyl-beta-D-glucuronide + UDP


name: NADP(+) + prostaglandin F2alpha => H(+) + NADPH + prostaglandin H2


name: 4-nitrocatechol + NADPH + O2 <=> 2-hydroxy-1,4-benzoquinone + H2O + NADP(+) + nitrite


name: MTMR4 binds phosphorylated SMAD2/3 (Drosophila melanogaster)


name: H(+) + NADH + O2 + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)


name: HEXB cleaves the terminal GalNAc from small HA fragments (Homo sapiens)


name: alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose = alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Sus scrofa)


name: 2-oxoglutarate + chrodrimanin E + O2 => chrodrimanin A + CO2 + succinate


name: COX15 transforms heme O to heme A (Rattus norvegicus)


name: JAK2 Phosphorylates IRS in Response to Leptin (Homo sapiens)


name: 1-O-hexadecyl-sn-glycero-3-phosphate + NADP(+) => 1-O-hexadecylglycerone 3-phosphate + H(+) + NADPH


name: lithocholate + NAD(+) => 3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: LRP2 binds extracellular TCN2:RCbl (Bos taurus)


name: L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: 3-O-(5'-adenylyl)-L-threonyl-[protein] + H2O = AMP + H(+) + L-threonyl-[protein]


name: AP2 binds chlorpromazine (Canis familiaris)


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Schizosaccharomyces pombe)


name: PEX3:PEX19:class I PMP dissociates (Rattus norvegicus)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1) = beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3)


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Schizosaccharomyces pombe)


name: PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + triacontanoate => H(+) + H2O + omega-hydroxy-triacontanoate + oxidized [NADPH--hemoprotein reductase]


name: D-xylose(out) + 2 Na(+)(out) => D-xylose(in) + 2 Na(+)(in)


name: adenosine(1914)/adenosine(1915) in 18S rRNA + 4 S-adenosyl-L-methionine <=> 4 H(+) + N(6)-dimethyladenosine(1914)/N(6)-dimethyladenosine(1915) in 18S rRNA + 4 S-adenosyl-L-homocysteine


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Canis familiaris)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Canis familiaris)


name: D-glucose 6-sulfate + NADP(+) => 6-sulfo-D-glucono-1,5-lactone + H(+) + NADPH


name: adenosine + H(+) + tuberculosinyl diphosphate => 1-tuberculosinyladenosine + diphosphate


name: Phosphorylated Cdc6 is exported from the nucleus (Saccharomyces cerevisiae)


name: an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + H(+) + UDP


name: "Linked to the hydrolysis of a nucleoside triphosphate"


name: 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Mus musculus)


name: CMP + phosphate => alpha-D-ribose 1,5-bisphosphate + cytosine


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Rattus norvegicus)


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Canis familiaris)


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Rattus norvegicus)


name: FN1 binds Collagen types I-V, VII (Xenopus tropicalis)


name: GPR161 is internalized (Xenopus tropicalis)


name: PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Mus musculus)


name: SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to PKL (Homo sapiens)


name: H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: KIT mutants bind type II TKIs (Homo sapiens)


name: NUMB:ITCH bind and ubiquitnate GLI1 (Canis familiaris)


name: 2,2-bis(4-hydroxyphenyl)-1-propanol + H2O + NAD(+) => bisphenol A + H(+) + NADH + O2


name: dodecanoyl-CoA + sn-glycerol 3-phosphate <=> 1-dodecanoyl-sn-glycerol 3-phosphate + CoA


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Drosophila melanogaster)


name: L-aspartate(in) + L-methionine(out) = L-aspartate(out) + L-methionine(in)


name: Thrombin-activated PARs activate G12/13 (Xenopus tropicalis)


name: (R)-2-hydroxy-3-methylbutyrate + NADP(+) = 3-methyl-2-oxobutanoate + H(+) + NADPH


name: all-trans-zeaxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => all-trans-antheraxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: D-maltohexaose + O2 <=> D-maltohexaono-1,5-lactone + H2O2


name: a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + O2 = a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + H2O + NAD(+)


name: AXIN is phosphorylated in the destruction complex (Homo sapiens)


name: H(+) + hexadecanoyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine


name: P2Y11 receptor can bind to ATP (Homo sapiens)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Dictyostelium discoideum)


name: 1-O-hexadecyl-2-acetyl-3-octanoyl-sn-glycerol + CoA => 1-O-hexadecyl-2-acetyl-sn-glycerol + octanoyl-CoA


name: 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: formaldehyde + H2O + NAD(+) => formate + 2 H(+) + NADH


name: an N-acylneuraminate + CTP = a CMP-N-acyl-beta-neuraminate + diphosphate


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Homo sapiens)


name: 2-dehydro-D-glucose + L-alanine => (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Bos taurus)


name: NCOA1 binds ESR1:estrogen:TGFA gene (Mus musculus)


name: MAP1LC3B binds KEAP1 and SQSTM1 (Homo sapiens)


name: NADP(+) + ursocholate <=> 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADPH


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Canis familiaris)


name: 3-(methylsulfanyl)propanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> 3-(methylsulfanyl)acryloyl-CoA + reduced [electron-transfer flavoprotein]


name: Electron transfer from ubiquinol to cytochrome c of complex III (Homo sapiens)


name: 3beta-hydroxy-beta-cyclocitral + crocetin dialdehyde => (3R)-3-hydroxy-8'-apo-beta-carotenal + O2


name: (E)-sinapyl alcohol + O2 = (E)-sinapaldehyde + H2O2


name: DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-cinerolone => cinerin II + CoA


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Canis familiaris)


name: Regulation of KIF23 (MKLP1) by phosphorylation (Canis familiaris)


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Homo sapiens)


name: H2O + N-acetylputrescine + O2 => 4-acetamidobutanal + H2O2 + NH4(+)


name: MADD exchanges GTP for GDP on RAB27 (Mus musculus)


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Homo sapiens)


name: Translocation of caspase-3 to the nucleus (Rattus norvegicus)


name: Recruitment of PAK to the membrane by binding active RAC1 (Gallus gallus)


name: L-dopa + O2 => 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)


name: (E)-isoeugenol + S-adenosyl-L-methionine <=> (E)-isomethyleugenol + H(+) + S-adenosyl-L-homocysteine


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Saccharomyces cerevisiae)


name: ATP + H2O + L-alanylglycine(out) <=> ADP + H(+) + L-alanylglycine(in) + phosphate


name: 2-methylsulfanyl-N(6)-(Delta(2)-isopentenyl)adenosine in tRNA + H(+) + NADPH + O2 = 2-methylsulfanyl-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine in tRNA + H2O + NADP(+)


name: mTORC1 binds RHEB:GTP (Xenopus tropicalis)


name: a 3-(omega-methylsulfanyl)alkylmalate => a 2-(omega-methylsulfanyl)alkylmaleate + H2O


name: SYK binds to integrin alphaIIb beta3 (Drosophila melanogaster)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Danio rerio)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Saccharomyces cerevisiae)


name: dihydromacarpine + H(+) + S-adenosyl-L-homocysteine => 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine


name: Interleukin-2 receptor alpha binds interleukin-2 (Sus scrofa)


name: ADAMTS13 cleaves VWF multimer (Sus scrofa)


name: Tachykinin receptor 1 (NK1) binds to substance P (Sus scrofa)


name: beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => all-trans-beta-carotene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 3,5-dimethylcyclohexanamine + H2O + NADP(+) => 3,5-dimethylcyclohexanone + H(+) + NADPH + NH4(+)


name: TREM,CD300 binds lipids (Xenopus tropicalis)


name: OGG1beta translocates to mitochondria (Drosophila melanogaster)


name: 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one (Homo sapiens)


name: SCF(SKP2) polyubiquitinates RUNX2 (Mus musculus)


name: 2-hydroxyadipate + NAD(+) => 2-oxoadipate + H(+) + NADH


name: (5S)-hydroxy-(6E,8Z)-octadecadienoate + glutathione disulfide + H2O => (5S)-hydroperoxy-(6E,8Z)-octadecadienoate + 2 glutathione


name: UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Mus musculus)


name: Ubiquitinated RNF41 binds P-USP8 (Bos taurus)


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Sus scrofa)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Mus musculus)


name: L-xylose + NADP(+) <=> H(+) + L-xylono-1,4-lactone + NADPH


name: 4-amino-5-aminomethyl-2-methylpyrimidine + H2O => 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)


name: COASY transfers an adenylyl group from ATP to PPANT (Canis familiaris)


name: a 1,2-saturated fatty acid + H2O2 => a 2-hydroxy fatty acid + H2O


name: (9Z,12Z)-octadecadienoate + glycerol + H(+) => 1-(9Z,12Z-octadecadienoyl)-glycerol + H2O


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Plasmodium falciparum)


name: CoA + H(+) + N-octadecanoyl-taurine => octadecanoyl-CoA + taurine


name: IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Homo sapiens)


name: AURKB phosphorylates TP53 (Xenopus tropicalis)


name: H2O + NADP(+) + senecionine N-oxide => NADPH + O2 + senecionine


name: 4 monapinone A + O2 <=> 2 dinapinone A + 2 H2O


name: RUNX3:CBFB binds the RORC gene promoter (Homo sapiens)


name: Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements (Sus scrofa)


name: PGRMC2:Hemes translocate to the nucleus (Dictyostelium discoideum)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-(9Z-octadecenoyl)-glycerol <=> 1,2-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: calcitetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (1S)-1,25-dihydroxy-24-oxocalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: Autocatalytic phosphorylation of FGFR3b (Gallus gallus)


name: PTK2beta binds alphaVbeta3 (Mus musculus)


name: Isomerization of GlcNAc6P to GlcNAc1P (Caenorhabditis elegans)


name: 16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate <=> 16alpha,17beta-estriol 16-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: (2S)-2-hydroxy-2-phenylpropanenitrile => acetophenone + hydrogen cyanide


name: RHOA:GTP:RTKN binds LIN7B (Rattus norvegicus)


name: (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + trans-aconitate


name: Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)


name: L-leucine(out) + L-ornithine(in) + Na(+)(out) = L-leucine(in) + L-ornithine(out) + Na(+)(in)


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Canis familiaris)


name: RHOC binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Mus musculus)


name: (2S)-2-amino-4-deoxychorismate + H2O => chorismate + NH4(+)


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Gallus gallus)


name: Expression of Proteasome activator complex subunit 2 (Homo sapiens)


name: ferruginol + O2 + reduced [NADPH--hemoprotein reductase] <=> 11-hydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 7,8-dihydropteroate + H2O => 4-aminobenzoate + 6-hydroxymethyl-7,8-dihydropterin


name: H(+) + NADPH + O2 + theophylline = 3-methylxanthine + formaldehyde + H2O + NADP(+)


name: JAK2 phosphorylation of GHR (Rattus norvegicus)


name: inosine + L-homocysteine => H2O + S-inosyl-L-homocysteine


name: L-phenylalanyl-L-methionine + L-tyrosylglycylglycine => H2O + Met-enkephalin


name: (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + O2 = (3R,6R)-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Xenopus tropicalis)


name: Hydrolysis of phosphatidylcholine (Danio rerio)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Homo sapiens)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Bos taurus)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Drosophila melanogaster)


name: 6-methyl-3,7-dioxodecanedioyl-CoA => (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H2O


name: 2-all-trans-nonaprenylphenol + CO2 => 4-hydroxy-3-all-trans-nonaprenylbenzoate + H(+)


name: SLC2A5 transports fructose from extracellular region to cytosol (Rattus norvegicus)


name: Translocation of ERBB4s80 to the nucleus (Canis familiaris)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Rattus norvegicus)


name: Interaction of integrin alphaDbeta2 with fibrin (Gallus gallus)


name: 4-methylcatechol + NAD(+) + nitrite => 3-nitrotoluene + NADH + O2


name: 1D-myo-inositol hexakisphosphate + ATP => 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Bos taurus)


name: Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Homo sapiens)


name: (9Z)-octadecenoate + taurine => H2O + N-(9Z-octadecenoyl)-taurine


name: GUCA binds Ca2+ to form GUCA:Ca2+ (Saccharomyces cerevisiae)


name: 3-oxododecanoyl-CoA + H(+) + NADH => (3S)-3-hydroxydodecanoyl-CoA + NAD(+)


name: [sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + S-adenosyl-L-methionine <=> 2-thio-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + H(+) + L-methionine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine => 2 a 1-acyl-sn-glycero-3-phosphocholine


name: beta-D-Gal-(1<->1')-Cer + H(+) + sulfate => 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + H2O


name: CYP26C1 4-hydroxylates 9cRA (Danio rerio)


name: p190RhoGAP binds Plexin-B1 (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> H2O + leukotriene A4


name: (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4(+) => H2O + O2 + serotonin


name: 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O <=> ADP + H(+) + N-acetyl-D-muramate 6-phosphate


name: H2O + N(1)-acetylspermidine + O2 <=> 3-aminopropanal + H2O2 + N-acetylputrescine


name: PGLYRP3,4 binds bacterial peptidoglycan (Xenopus tropicalis)


name: a nitrile + 2 H2O <=> a carboxylate + NH4(+)


name: 6-deoxy-6-sulfo-D-fructose + ATP => 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H(+)


name: H(+)(out) + L-alanine(out) => H(+)(in) + L-alanine(in)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Bos taurus)


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Homo sapiens)


name: E2-mediated FOS gene expression (Homo sapiens)


name: (3S)-hydroxyeicosanoyl-CoA + NAD(+) => 3-oxoeicosanoyl-CoA + H(+) + NADH


name: TFRC dimer binds 2xholoTF (Mus musculus)


name: D-isoleucine + H2O + O2 <=> (R)-3-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: Dissociation of L13a from the 60s ribosomal subunit (Sus scrofa)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Dictyostelium discoideum)


name: atRAL binds to RBP2 (Xenopus tropicalis)


name: IL10 dimer binds IL10RA:JAK1 (Xenopus tropicalis)


name: HMGB1 binds TLR4:LY96 (Canis familiaris)


name: Furin cleaves pro-protein C to protein C (Danio rerio)


name: (S)-methylmalonyl-CoA + H(+)(out) + Na(+)(in) <=> CO2 + Na(+)(out) + propanoyl-CoA


name: coelenterazine h dioxetanone => coelenterazine h + O2


name: (1R,5S)-carveol + NAD(+) <=> (S)-carvone + H(+) + NADH


name: DVL1 is ubiquitinated by HECW1 (Bos taurus)


name: 3alpha(S)-strictosidine + H2O => secologanin + tryptamine


name: MDH2 dimer dehydrogenates MAL (Danio rerio)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Mus musculus)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Caenorhabditis elegans)


name: RHOBTB3 hydrolyzes ATP (Canis familiaris)


name: PIAS1,3 SUMOylates NR5A1 with SUMO2 (Sus scrofa)


name: dTDP-beta-L-daunosamine + epsilon-rhodomycinone <=> dTDP + H(+) + rhodomycin D


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Canis familiaris)


name: acetyl-CoA + an aliphatic alcohol = an acetyl ester + CoA


name: TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers and YY1 stimulate ERBB2 gene expression (Homo sapiens)


name: D-glucose + NADP(+) = 6-dehydro-D-glucose + H(+) + NADPH


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Rattus norvegicus)


name: PLCG1 binds to p-ERBB2:p-EGFR (Homo sapiens)


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Xenopus tropicalis)


name: 24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase] = 32-hydroxy-24,25-dihydrolanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + (S)-mandelate + O2 => (6R)-L-erythro-6,7-dihydrobiopterin + (S)-4-hydroxymandelate + H2O


name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Mus musculus)


name: 2 (S)-lactate(in) + prostaglandin H2(out) => 2 (S)-lactate(out) + prostaglandin H2(in)


name: Multiple proteins are localized at replication fork (Homo sapiens)


name: L-lysyl-[histone] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: ATM phosphorylates TTC5 (Rattus norvegicus)


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Drosophila melanogaster)


name: 4-O-(beta-D-glucosyl)-(E)-coniferol + H2O => (E)-coniferol + D-glucose


name: valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)


name: cholesteryl 3-beta-D-xyloside + N-(9Z-octadecenoyl)-sphing-4-enine => beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + cholesterol


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Bos taurus)


name: luteolin + UDP-alpha-D-glucose <=> H(+) + isoorientin + UDP


name: 3-(4-hydroxyphenyl)pyruvate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tyrosine


name: dodecanoyl-CoA + FAD + H(+) <=> (2E)-dodecenoyl-CoA + FADH2


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Xenopus tropicalis)


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Homo sapiens)


name: 1-hexadecanoylglycerone 3-phosphate + tetradecan-1-ol => 1-O-tetradecylglycerone 3-phosphate + H(+) + hexadecanoate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Bos taurus)


name: Interaction of Tie2 and Grb14 (Sus scrofa)


name: FGFR1c binds to Klotho-bound FGF23 (Xenopus tropicalis)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP-N-acetyl-beta-neuraminate <=> an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP + H(+)


name: p-S446-IRF5 dimer translocates to the nucleus (Canis familiaris)


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Drosophila melanogaster)


name: ESTG binds ESR2:chaperone complex (Xenopus tropicalis)


name: glyoxylate(in) + oxalate(out) => glyoxylate(out) + oxalate(in)


name: acetyl-CoA + L-methionine = CoA + H(+) + N(alpha)-acetyl-L-methionine


name: SUMOylation of NFKB2 with SUMO1 (Sus scrofa)


name: AMP + diphosphate + dodecanoyl-CoA => ATP + CoA + dodecanoate


name: cysteine-type endopeptidase activity involved in apoptotic process


name: The PIDDosome activates CASP2 (Homo sapiens)


name: isoepoxydon + NADP(+) => H(+) + NADPH + phyllostine


name: Heterodimerization of E proteins with Myod (Homo sapiens)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1)


name: precorrin-2 + S-adenosyl-L-methionine <=> H(+) + precorrin-3A + S-adenosyl-L-homocysteine


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Dictyostelium discoideum)


name: 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide] => an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide]


name: a 5'-end ribonucleotide-tRNA(His) + ATP + GTP + H2O => a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)


name: 1,7-dimethylxanthine + S-adenosyl-L-methionine = caffeine + H(+) + S-adenosyl-L-homocysteine


name: (S)-cis-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] <=> allocryptopine + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Bos taurus)


name: Inactive G alpha (q) reassociates with G beta:gamma (Gallus gallus)


name: GBF1 stimulates ARF nucleotide exchange (Saccharomyces cerevisiae)


name: 13-cis-retinyl hexadecanoate + CoA => 13-cis-retinol + hexadecanoyl-CoA


name: ERBB4s80:ESR1 binds ERBB4 gene promoter (Homo sapiens)


name: Fibronectin degradation by ADAM8 (Gallus gallus)


name: a short-chain (3R)-hydroxy fatty acyl-CoA = a short-chain (2E)-enoyl-CoA + H2O


name: TP53 binds the IKBIP gene promoter (Homo sapiens)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Canis familiaris)


name: DHFR dimer binds DHFR inhibitors (Caenorhabditis elegans)


name: H2O + octadecanoyl-CoA <=> CoA + H(+) + octadecanoate


name: MMACHC:cob(II)alamin binds MMADHC (Caenorhabditis elegans)


name: 2'-O-methylcytidine(1920) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(1920) in 23S rRNA + S-adenosyl-L-methionine


name: 1-nitrocyclohexan + NADP(+) <=> 1-nitrocyclohexene + H(+) + NADPH


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Xenopus tropicalis)


name: PIAS1 SUMOylates THRB with SUMO1. (Rattus norvegicus)


name: Activated PCLG1 dissociates from NTRK3 (Rattus norvegicus)


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Canis familiaris)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Canis familiaris)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Drosophila melanogaster)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Bos taurus)


name: T1R1/T1R3 dimer is the umami taste receptor (Bos taurus)


name: 3beta-hydroxyandrost-5-en-17-one + O2 + reduced [NADPH--hemoprotein reductase] = 3beta,7alpha-dihydroxyandrost-5-en-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: A + keto-L-sorbose = 5-dehydro-D-fructose + AH2


name: (4R)-hydroxysphinganine + docosanoyl-CoA = CoA + H(+) + N-docosanoyl-(4R)-hydroxysphinganine


name: MAPK12 phosphorylates PTPN3 (Gallus gallus)


name: PDCL promotes G-protein beta 5 folding (Mus musculus)


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Mus musculus)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Xenopus tropicalis)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + 1,3-di-(9Z,12Z)-octadecadienoylglycerol + H(+) => 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O


name: RHOG binds effectors at the ER membrane (Homo sapiens)


name: H2O + progoitrin = (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Canis familiaris)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Xenopus tropicalis)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Caenorhabditis elegans)


name: 3-hydroxyhexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 3,16-dihydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + 7 CO2 + 8 CoA + 2 H2O => acetyl-CoA + 7 H(+) + 7 malonyl-CoA


name: 3',3'-cGAMP(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) <=> 3',3'-cGAMP(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: IL12 bound to IL12R internalises (Bos taurus)


name: CDC42 GEFs activate CDC42 (Saccharomyces cerevisiae)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Xenopus tropicalis)


name: HCO3- transport through ion channel (Caenorhabditis elegans)


name: Binding of RRN3 to RNA Polymerase I (Sus scrofa)


name: CTP(in) + GDP(out) => CTP(out) + GDP(in)


name: (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + H(+) + UDP => 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose


name: (9Z,12Z)-octadecadienoyl-CoA + AH2 + O2 <=> (9Z,12Z,15Z)-octadecatrienoyl-CoA + A + 2 H2O


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Dictyostelium discoideum)


name: E-cadherin degradation by PS1:NCSTN (Gamma-secretase) (Homo sapiens)


name: Full-length SPZ dimer is cleaved by EA/SPE serine protease (Drosophila melanogaster)


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Saccharomyces cerevisiae)


name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + 1,2-dihexanoylglycerol => 1,2-dihexanoyl-3-(7Z,10Z,13Z-hexadecatrienoyl)-glycerol + CoA


name: 2 (R)-3-phenyllactate + 2 (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine <=> 8 AMP + 8 diphosphate + 8 H(+) + PF1022A + 4 S-adenosyl-L-homocysteine


name: alpha-maltose 6'-phosphate + H2O => D-maltose + phosphate


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Danio rerio)


name: MMACHC dealkylates RCbl (Dictyostelium discoideum)


name: PICALM binds R-SNAREs (Canis familiaris)


name: ATP + CoA + hexanoate => AMP + diphosphate + hexanoyl-CoA


name: H2O + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = (9Z)-octadecenoate + H(+) + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: 2 S-adenosyl-L-methionine + sphing-4-enine => 2 H(+) + N,N-dimethylsphing-4-enine + 2 S-adenosyl-L-homocysteine


name: Activated PLC gamma dissociates from the PDGF receptor (Rattus norvegicus)


name: factor VIIIa + factor IXa -> factor VIIIa:factor IXa (Mus musculus)


name: S-adenosyl-L-methionine + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine


name: Nuclear translocation of catalytic domain of Mst3 (Gallus gallus)


name: HOXB1 activates HOXA2 expression (Homo sapiens)


name: MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) (Canis familiaris)


name: ARL6:GTP and the BBSome bind ciliary cargo (Canis familiaris)


name: 11beta,17beta-dihydroxyandrost-4-ene-3-one + NADP(+) => 11beta-hydroxyandrost-4-ene-3,17-dione + H(+) + NADPH


name: long-chain fatty acid omega-1 hydroxylase activity


name: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Canis familiaris)


name: ECHS1 hydrates methacrylyl-CoA (Mus musculus)


name: lipoxin B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-lipoxin B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTPN3 dephosphorylates MAPK12 (Mus musculus)


name: (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O => 2-formylbenzoate + pyruvate


name: Nucleotide exchange on RAB1 (Plasmodium falciparum)


name: Defective GUSB does not hydrolyse (HA)2 (Homo sapiens)


name: NLK phosphorylates TCF/LEF (Mus musculus)


name: Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 (Homo sapiens)


name: Defective SLC5A1 does not cotransport Glc and Na+ (Homo sapiens)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Sus scrofa)


name: a cytidine in tRNA + acetyl-CoA + ATP + H2O <=> ADP + an N(4)-acetylcytidine in tRNA + CoA + H(+) + phosphate


name: 1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: a 1,2-diacyl-sn-glycerol + CTP <=> a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H(+)


name: ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate + H(+) + H2O


name: Phosphorylation and activation of eIF4B by activated S6K1 (Canis familiaris)


name: CBLIF binds RCbl (Drosophila melanogaster)


name: 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = a fatty acid + acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+)


name: PAK1 phosphorylates LIMK1 (Rattus norvegicus)


name: H2O + N-(9Z-octadecenoyl)-L-leucine <=> (9Z)-octadecenoate + L-leucine


name: 11a-hydroxytetracycline + H2O + NADP(+) => H(+) + NADPH + O2 + tetracycline


name: N(pros)-phospho-L-histidyl-[protein] + N-acetyl-beta-D-muramate(out) => L-histidyl-[protein] + N-acetyl-beta-D-muramate 6-phosphate(in)


name: calcium-dependent phospholipase C activity


name: [thyroglobulin]-3-iodo-L-tyrosine + H(+) + H2O2 + iodide => [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O


name: sphingolipid delta-4 desaturase activity


name: Activated FGFR4 binds PLCG1 (Gallus gallus)