name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + holo-[ACP] => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + tetradecanoyl-[ACP]


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Canis familiaris)


name: MTORC1 dissociates from ULK complex (Sus scrofa)


name: Transport of the export-competent mRNP complex through the NPC (Rattus norvegicus)


name: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2


name: CTP + N,N-diacetyllegionaminate = CMP-N,N-diacetyllegionaminate + diphosphate


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + cholesterol <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z-octadecenoate)


name: 2 H(+) + NADH + O2 + phenazine-1-carboxylate <=> 1-hydroxyphenazine + CO2 + H2O + NAD(+)


name: ppDVL binds DAAM1 (Caenorhabditis elegans)


name: Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Mus musculus)


name: (indol-3-yl)acetate + NH4(+) => (indol-3-yl)acetonitrile + 2 H2O


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Canis familiaris)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Schizosaccharomyces pombe)


name: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate


name: SDK2 homophillic interaction (Canis familiaris)


name: CBL dissociates from ubiquitinated p-SPRY2 (Sus scrofa)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + glycerol + H(+)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Mus musculus)


name: an N-acyl-D-mannosamine + NAD(+) => an N-acyl-D-mannosaminolactone + H(+) + NADH


name: uridine(31) in tRNA = pseudouridine(31) in tRNA


name: H2O2 + imidazole-4-acetaldehyde + NH4(+) => H2O + histamine + O2


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Mus musculus)


name: Association of Acrosin Heavy and Light Chain (Mus musculus)


name: (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate => (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2


name: P2Y9 receptor can bind to LPA (Homo sapiens)


name: eicosanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(2-oxohenicosyl)pyran-2-one + 3 CO2 + 4 CoA


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Canis familiaris)


name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Gallus gallus)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Canis familiaris)


name: diphosphate + H2O + L-threonylcarbamoyladenylate => ATP + hydrogencarbonate + L-threonine


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose => dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O


name: gamma-secretase cleaves EPHB2 (Bos taurus)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Canis familiaris)


name: H(+) + NADPH + prostaglandin D2-ethanolamide => 11beta-prostaglandin F2-ethanolamide + NADP(+)


name: FOXO1,FOXO3 and SMAD3 bind TRIM63 gene promoter (Homo sapiens)


name: Formation of ADAR2  homodimer (Sus scrofa)


name: 4-methylsulfanyl-2-oxobutanoate + an aromatic L-alpha-amino acid => an aromatic oxo-acid + L-methionine


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Mus musculus)


name: 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3beta-hydroxy-5alpha-androstan-17-one + O2 + reduced [NADPH--hemoprotein reductase]


name: 5-methyldeoxycytidine diphosphate + ADP => 5-methyldeoxycytidine 5'-phosphate + ATP


name: (2E,6E)-farnesyl diphosphate = alpha-guaiene + diphosphate


name: Kinesin-13 is a dimer (Rattus norvegicus)


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Homo sapiens)


name: RDH5 oxidises 11cROL to 11cRAL (Sus scrofa)


name: ULK1 Translocates to the mitochondria (Caenorhabditis elegans)


name: (E)-coniferaldehyde + H2O + NAD(+) <=> (E)-ferulate + 2 H(+) + NADH


name: p-AMPK:AMP binds the ULK complex (Homo sapiens)


name: Monoiodinated tyrosine can be deiodinated (Danio rerio)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP => an N-acylsphing-4-enine + UDP-alpha-D-glucose


name: beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose <=> beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP + H(+)


name: H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) => 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Sus scrofa)


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Rattus norvegicus)


name: acetylsalicylate + H2O = acetate + H(+) + salicylate


name: a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: Connexin oligomerization in endoplasmic reticulum membrane (Xenopus tropicalis)


name: D-galactose(in) + H(+)(in) <=> D-galactose(out) + H(+)(out)


name: PSMD14 cleaves K63-linked ubiquitin (Xenopus tropicalis)


name: Receptor CCR6 binds CCL20 ligand (Mus musculus)


name: JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)


name: (R)-beta-alanopine + H2O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate


name: 2 Fe(2+) + 2 H2O + H2O2 => 6 H(+) + 2 iron(III) oxide-hydroxide


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O => a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: H2O + N(omega)-methyl-L-arginine = L-citrulline + methylamine


name: STAT4 binds IL12RB2:IL12RB2 (Xenopus tropicalis)


name: (3E)-decenoyl-CoA + NADP(+) => (2E,4E)-decadienoyl-CoA + H(+) + NADPH


name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Sus scrofa)


name: (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2


name: USP13 deubiquitinates BECN1,USP10 (Canis familiaris)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Gallus gallus)


name: SGT1:HSP90 binds inactive NLRP3 (Sus scrofa)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Homo sapiens)


name: Hh-Np traffics to the plasma membrane (Drosophila melanogaster)


name: Formation of translation initiation complexes containing mRNA that does not circularize (Saccharomyces cerevisiae)


name: 1D-myo-inositol 2-phosphate + H2O => myo-inositol + phosphate


name: apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + ATP + biotin = AMP + diphosphate + H(+) + holo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)]


name: USP33 deubiquitinates CCP110,ARRB (Xenopus tropicalis)


name: BIL binds GSTA1, FABP1 (Caenorhabditis elegans)


name: ATP hydrolysis by HSP70 (Plasmodium falciparum)


name: 9,10-epoxyoctadecanoate + H2O => 9,10-dihydroxyoctadecanoate


name: hydrolase activity, acting on ester bonds


name: MAOA:FAD deaminates 3MT to HVA (Dictyostelium discoideum)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine + ethanolamine


name: a ribonucleoside 5'-triphosphate + phytyl phosphate => a ribonucleoside 5'-diphosphate + phytyl diphosphate


name: AKT1S1 (PRAS40) binds mTORC1 (Rattus norvegicus)


name: a long-chain fatty acyl-CoA + a sterol <=> a sterol ester + CoA


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Xenopus tropicalis)


name: GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Bos taurus)


name: 2-oxoglutarate + 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + CO2 + succinate


name: RHOD:GTP translocates to the endosome membrane (Drosophila melanogaster)


name: 3-methylbutanoyl-CoA + 3 H(+) + 3 malonyl-CoA => 3 CO2 + 4 CoA + phlorisovalerophenone


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 2 Fe(III)-[cytochrome b5] + 2 H2O + N-acyl-(4E,8E,10E)-sphingatrienine


name: D-glucose(out) + N(pros)-phospho-L-histidyl-[protein] => D-glucose 6-phosphate(in) + L-histidyl-[protein]


name: DAG stimulates protein kinase C-delta (Schizosaccharomyces pombe)


name: PPT2 hydrolyses PALMCoA to PALM (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O <=> a 1-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: inositol heptakisphosphate kinase activity


name: Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)


name: BP180 interacts intracellularly with plectin and integrin beta4 (Canis familiaris)


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Canis familiaris)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate => benzyl thiocyanate + sulfate


name: all-trans-4,4'-diapolycopene + FADH2 => all-trans-4,4'-diaponeurosporene + FAD + H(+)


name: NF-kappaB translocates from the cytosol to the nucleus (Xenopus tropicalis)


name: Phosphorylation of YAP by LATS2 (Sus scrofa)


name: 1-(9S,13S-12-oxo-10,15Z-phytodienoyl)-2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = (9S,13S,15Z)-12-oxophyto-10-15-dienoate + 2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+)


name: ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Homo sapiens)


name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Drosophila melanogaster)


name: Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 and inhibited by VENTX:TCF4,LEF1 (Homo sapiens)


name: SERPINC1 binds SERPINC1 activators (Homo sapiens)


name: GLI1 binds HHIP gene, PTCH2 gene and BOC gene promoters (Homo sapiens)


name: all-trans-3-hydroxyretinol + H2O + 2 oxidized [adrenodoxin] => all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: D-glucuronate(out) + H(+)(out) => D-glucuronate(in) + H(+)(in)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Homo sapiens)


name: Phosphorylation of cPLA2 by ERK-2 (Schizosaccharomyces pombe)


name: NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)


name: HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Mus musculus)


name: 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Rattus norvegicus)


name: 4-hydroxybenzoate + all-trans-decaprenyl diphosphate <=> 4-hydroxy-3-all-trans-decaprenylbenzoate + diphosphate


name: (R)-2-hydroxyglutarate + FAD + H(+) => 2-oxoglutarate + FADH2


name: CREB3L3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Danio rerio)


name: (4R)-hydroxysphing-(8E)-enine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphing-(8E)-enine


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Caenorhabditis elegans)


name: AH2 + menaquinone-9 <=> A + beta-dihydromenaquinone-9


name: RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Homo sapiens)


name: 1-phenylpropan-1-one + L-alanine => 1-phenylpropylamine + pyruvate


name: 15,17(3)-seco-F430-17(3)-acid + ATP = ADP + coenzyme F430 + phosphate


name: (2E,6E)-farnesyl phosphate + CDP + H(+) => (2E,6E)-farnesol + CTP


name: (R)-tembetarine + H(+) + S-adenosyl-L-homocysteine => (R)-reticuline + S-adenosyl-L-methionine


name: ATF2 acetylates histone H2B, H4 (Rattus norvegicus)


name: EET(1) is hydrolysed to DHET(1) by EPHX2 (Rattus norvegicus)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Gallus gallus)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Dictyostelium discoideum)


name: K63polyUb-TAK1 autophosphorylates (Gallus gallus)


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(8)-citryl-spermidine <=> H(+) + holo-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8)-citryl-spermidine


name: methylammonium transmembrane transporter activity


name: p-Y705-STAT3 dimerizes (Canis familiaris)


name: ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine


name: Efflux of glucose and orthophosphate from the endoplasmic reticulum (Gallus gallus)


name: G-protein subunits dissociate from WNT:FZD complex (Homo sapiens)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Canis familiaris)


name: LIPs hydrolyze TG to DAG and LCFA (Canis familiaris)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Caenorhabditis elegans)


name: (9Z)-octadecenoate + H(+) + sn-glycero-3-phospho-L-serine => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O


name: SYK autophosphorylates at the activated BCR (Mus musculus)


name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Canis familiaris)


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Mus musculus)


name: atrochrysone carboxyl-[ACP] + H2O = atrochrysone carboxylate + H(+) + holo-[ACP]


name: ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2 <=> ergosterol + 2 H2O + NADP(+)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Homo sapiens)


name: 3-oxo-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + NADP(+)


name: Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Rattus norvegicus)


name: alpha-D-galactose 1-phosphate + 2 H(+) + UMP => H2O + UDP-alpha-D-glucose


name: TBX5 and KAT5 bind the SRF gene (Homo sapiens)


name: a 1,2-diacyl-3-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base <=> a 1,2-diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base


name: RAS proteins are depalmitoylated (Mus musculus)


name: SYK binds to p-Y65,Y76-FCER1G (Homo sapiens)


name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Gallus gallus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2xTRAP hydrolyzes FMN to RIB (Bos taurus)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Bos taurus)


name: Pink1 is cleaved on healthy mitochondria (Sus scrofa)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Bos taurus)


name: 9beta-pimara-7,15-dien-19-ol + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Caspase-mediated cleavage of Desmoglein 3 (Gallus gallus)


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Gallus gallus)


name: CDC42 GEFs activate CDC42 (Mus musculus)


name: nitric oxide + superoxide = peroxynitrite


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Bos taurus)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: 15-cis-4,4'-diapophytoene + FAD + H(+) => all-trans-4,4'-diapophytofluene + FADH2


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-L-ribitol <=> 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex  (Homo sapiens)


name: GSDME (1-270) binds cardiolipin (Sus scrofa)


name: (10bR,4aS)-oxomaritidine + NADP(+) => (10bR,4aS)-noroxomaritidine + H(+) + NADPH


name: Release of docked serotonin loaded synaptic vesicle (Mus musculus)


name: Ghrelin O-acyltransferase octanoylates Proghrelin (Canis familiaris)


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe (Homo sapiens)


name: Dissociation of  transcript with 5'-GMP from GT (Rattus norvegicus)


name: GABA loaded synaptic vesicle Docking and Priming (Xenopus tropicalis)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)


name: Inactivation of Myt1 kinase (Caenorhabditis elegans)


name: Phosphorylation and activation of eIF4B by activated S6K1 (Homo sapiens)


name: LRP1:Hemopexin:heme is endocytosed (Rattus norvegicus)


name: Duplex siRNA is loaded into Argonaute (Gallus gallus)


name: ATP + H(+) + L-glutamate => diphosphate + L-glutamyl-5'-AMP


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Schizosaccharomyces pombe)


name: Formation of AT-AC C complex (Xenopus tropicalis)


name: Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region (Homo sapiens)


name: MECP2 binds the SIN3A co-repressor complex (Xenopus tropicalis)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Xenopus tropicalis)


name: Elongation by Pol zeta complex (Gallus gallus)


name: Slo3 Potassium Transport (Drosophila melanogaster)


name: Ubiquitinated geminin is degraded by the proteasome (Sus scrofa)


name: Spike Trimer Translocates to the Plasma Membrane (Homo sapiens)


name: an (11Z,14Z)-icosadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Danio rerio)


name: Parenchymal atROL translocates to HSCs (Mus musculus)


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Xenopus tropicalis)


name: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate <=> a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate


name: dec-9-enoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => decanoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Auto-ubiquitination of TRAF3 (Bos taurus)


name: Co-precorrin-2 + S-adenosyl-L-methionine = Co-precorrin-3 + H(+) + S-adenosyl-L-homocysteine


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: H(+) + H2O + hydroxyatrazine <=> ethylamine + N-isopropylammelide


name: a phosphatidylglycerol phosphate + H2O <=> a phosphatidylglycerol + phosphate


name: CPT1A,B transfers PALM to CAR (Mus musculus)


name: H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] => N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase]


name: CoA + H(+) + N-(9Z,12Z-octadecadienoyl)-glycine => (9Z,12Z)-octadecadienoyl-CoA + glycine


name: Formation of the cap-binding eIF4F complex (Mus musculus)


name: E2F7 and E2F8 homo- and heterodimers inhibit E2F1 expression (Homo sapiens)


name: L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: "type III protein arginine methyltransferase"


name: CoA(out) + NAD(+)(in) => CoA(in) + NAD(+)(out)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Bos taurus)


name: (9Z)-octadecenoyl-CoA + hexadecan-1-ol <=> CoA + hexadecanyl (9Z)-octadecenoate


name: (2E,6E)-farnesyl diphosphate + H2O => diphosphate + discoidol


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Rattus norvegicus)


name: a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GD1b (d18:1(4E)) + H2O


name: CYP7B1 7-hydroxylates 25OH-CHOL (Bos taurus)


name: 3-methylbutanoyl-CoA + H(+) + malonyl-[ACP] = 5-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA


name: 5-guanidino-2-oxopentanoate + H(+) => 4-guanidinobutanal + CO2


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Xenopus tropicalis)


name: glyphosate + H2O + O2 = aminomethylphosphonate + glyoxylate + H(+) + H2O2


name: SRD5A3 dehydrogenates TEST to DHTEST (Caenorhabditis elegans)


name: DHFR2 reduces FOLA to DHF (Homo sapiens)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Xenopus tropicalis)


name: VCAM1 binds Integrin alpha4beta1 (Bos taurus)


name: (2R,4S)-ketoconazole(in) + ATP + H2O <=> (2R,4S)-ketoconazole(out) + ADP + H(+) + phosphate


name: 2-methyl-3-oxopropanoate + L-alanine => (R)-3-amino-2-methylpropanoate + pyruvate


name: 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Gallus gallus)


name: Virion-associated M2 protein mediated ion infusion (Homo sapiens)


name: Thrombin-activated PARs:G12/13 (active) dissociate (Caenorhabditis elegans)


name: STUB1 ubiquitinates RIPK3 at K55, K363 (Sus scrofa)


name: deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Bos taurus)


name: 2-hexadecanoylglycerol + H2O = glycerol + H(+) + hexadecanoate


name: 2-methoxy-4-vinylphenol + H(+) + NADH = 4-ethyl-2-methoxyphenol + NAD(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 <=> 8-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate


name: EP2 and EP4 receptors can bind PGE2 (Homo sapiens)


name: AH2 + L-isoleucyl-[protein] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + methylcyclopropylglycine-[protein]


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O <=> 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate


name: GLB1 hydrolyzes SapB/C:LacCer (Drosophila melanogaster)


name: 2-oxoglutarate + decanoyl-CoA + O2 <=> 2-hydroxydecanoyl-CoA + CO2 + succinate


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Sus scrofa)


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Drosophila melanogaster)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O = acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative


name: L3MBTL1 binds TP53 monomethylated on K382 (Sus scrofa)


name: 2 H(+) + hexadecanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (6Z)-hexadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Sus scrofa)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: MYSM1 deubiquitinates Histone H2A (Rattus norvegicus)


name: 13-(beta-D-glucosyloxy)docosanoate + H(+) + UDP => 13-hydroxydocosanoate + UDP-alpha-D-glucose


name: IL21 receptor STAT phosphorylation (Mus musculus)


name: NFE2L2 binds the SRXN1 gene (Homo sapiens)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Sus scrofa)


name: MRN complex binds CDK2 and RBBP8 (Canis familiaris)


name: Phosphorylation of CARMA1 (Rattus norvegicus)


name: H(+) + isatin + NADPH <=> 3-hydroxyindolin-2-one + NADP(+)


name: 3-dehydro-6-deoxo-28-norteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 6-dehydro-28-norteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: SPRY2 is serine phosphorylated in response to MAPK activation (Homo sapiens)


name: Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Drosophila melanogaster)


name: H2O + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD(+) => (S)-2,3-diaminopropanoate + 2-oxoglutarate + H(+) + NADH


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Mus musculus)


name: (9Z)-octadecenoate + 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H(+) => 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H2O


name: L-arginine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) <=> L-arginine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: SUMOylation of TDG with SUMO2,3 (Danio rerio)


name: GRB2:SOS interacts with p-KIT (Mus musculus)


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Xenopus tropicalis)


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Gallus gallus)


name: MTMR14, MTMR3 dephosphorylate PI3P (Schizosaccharomyces pombe)


name: DCC interacts with DIP13alpha (Rattus norvegicus)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Mus musculus)


name: ATP + hydrogencarbonate + propanoyl-CoA => (S)-methylmalonyl-CoA + ADP + H(+) + phosphate


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate


name: AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Bos taurus)


name: (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O => (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2


name: PIAS4 SUMOylates NR4A2 with SUMO2,3 (Homo sapiens)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Dictyostelium discoideum)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Xenopus tropicalis)


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Mus musculus)


name: (20S)-protopanaxadiol + 2 D-glucose => (20S)-ginsenoside Rg3 + 2 H2O


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Mus musculus)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16,17-epoxy-(7Z,10Z,13Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: mRNA9 is translated to Nucleoprotein (Homo sapiens)


name: H2O + N-(aminomethyl)urea = N-(hydroxymethyl)urea + NH4(+)


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Homo sapiens)


name: ATG7:ATG3:LC3 dissociates (Caenorhabditis elegans)


name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Rattus norvegicus)


name: (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+) => (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+)


name: H2O + nitrite + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + nitrate + 2 reduced [2Fe-2S]-[ferredoxin]


name: 5,6-dihydrouracil + NADP(+) => H(+) + NADPH + uracil


name: cAMP induces dissociation of inactive PKA tetramers (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + sulfate


name: TP receptor can bind thromboxane (Rattus norvegicus)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycerol + UDP-alpha-D-galactose = 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Canis familiaris)


name: Degradation of ubiquitinated SKI/SKIL (Gallus gallus)


name: LIAS synthesizes lipoyl-GCSH (Gallus gallus)


name: NADH:ubiquinone reductase (non-electrogenic) activity


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Gallus gallus)


name: PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins (Rattus norvegicus)


name: beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp + H2O => alpha-D-mannopyranose + beta-D-mannopyranosyl-(1->2)-D-mannopyranose


name: 3'-dehydrocarminate + H2O2 => carminate + O2


name: Nuclear translocation of catalytic domain of Mst3 (Homo sapiens)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3  phosphorylates STAT1,STAT3 (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-hedycaryol + diphosphate


name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene (Homo sapiens)


name: IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Mus musculus)


name: acetyl-CoA + N-terminal L-methionyl-L-isoleucyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein]


name: AMP + H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase] => holo-[(phenol)carboxyphthiodiolenone synthase] + icosanoyl-AMP


name: Clusterin binds C5b-C7, C8, C9 (Mus musculus)


name: (7Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Canis familiaris)


name: ATP + CoA + OPC-6 <=> AMP + diphosphate + OPC-6-CoA


name: L-arginine(in) + L-methionine(out) + Na(+)(out) <=> L-arginine(out) + L-methionine(in) + Na(+)(in)


name: acetyl-CoA + 8 H(+) + holo-[ACP] + 8 malonyl-CoA <=> 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + 8 CO2 + 9 CoA + 2 H2O


name: ornithine decarboxylase inhibitor activity


name: ADORA2A,B bind Ade-Rib (Canis familiaris)


name: CDK4 inhibitors bind CDK4 (Rattus norvegicus)


name: TCN2 binds RCbl in the circulation (Sus scrofa)


name: SMURF2 monoubiquitinates SMAD3 (Homo sapiens)


name: (20S)-hydroxypregn-4-en-3-one + NADP(+) => H(+) + NADPH + progesterone


name: D-glucosamine 6-phosphate <=> D-galactosamine 6-phosphate


name: 2-oxoglutarate + [2-(trimethylamino)ethyl]phosphonate + O2 => [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + CO2 + succinate


name: H(+) + L,L-cystathionine + succinate => L-cysteine + O-succinyl-L-homoserine


name: (2R)-3-sulfolactate <=> H(+) + pyruvate + sulfite


name: Assembly of an Active Transcription Complex (Homo sapiens)


name: COMT transfers Met to DOPAC to form HVA (Bos taurus)


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Dictyostelium discoideum)


name: L-altrarate <=> 5-dehydro-4-deoxy-D-glucarate + H2O


name: phosphorelay response regulator activity


name: IkB is ubiquitinated and degraded (Sus scrofa)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Xenopus tropicalis)


name: Tankyrase binds AXIN (Rattus norvegicus)


name: [protein]-dithiol + ATP + S-hydroxy-S-oxy-L-cysteinyl-[peroxiredoxin] <=> [protein]-disulfide + ADP + phosphate + S-hydroxy-L-cysteinyl-[peroxiredoxin]


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Mus musculus)


name: 3-oxooctanoyl-[ACP] + CO2 + CoA => H(+) + hexanoyl-CoA + malonyl-[ACP]


name: ADP + thiamine triphosphate => ATP + thiamine diphosphate


name: cytidine transmembrane transporter activity


name: Activated FGFR1 phosphorylates SHC1 (Sus scrofa)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Xenopus tropicalis)


name: glycochenodeoxycholate + NAD(+) => 7-oxoglycolithocholate + H(+) + NADH


name: IL20 binds to IL22RA1:JAK1:IL20RB (Mus musculus)


name: CYSLT2 binds LTC4,LTD4,LTE4 (Homo sapiens)


name: 2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine = 2-heptyl-1-methoxy-4(1H)-quinolinone + H(+) + S-adenosyl-L-homocysteine


name: RAS GEFs promote RAS nucleotide exchange (Homo sapiens)


name: archaeosine(15) in tRNA + L-glutamate => 7-cyano-7-carbaguanosine(15) in tRNA + H2O + L-glutamine


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Sus scrofa)


name: acetaldehyde + glycine => D-allo-threonine


name: Activated JNKs phosphorylate c-JUN (Bos taurus)


name: H(+)(out) + K(+)(in) + L-aspartate(out) + 3 Na(+)(out) <=> H(+)(in) + K(+)(out) + L-aspartate(in) + 3 Na(+)(in)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Rattus norvegicus)


name: ADP + H(+) + Na(+)(out) + phosphate => ATP + H2O + Na(+)(in)


name: LIG1 binds APEX1 and PCNA at SSB (Plasmodium falciparum)


name: KAT6A acetylates TP53 (Canis familiaris)


name: ADP(in) + ATP(out) <=> ADP(out) + ATP(in)


name: 4-acetoxybenzyl alcohol + NAD(+) = 4-acetoxybenzaldehyde + H(+) + NADH


name: imaginal disc growth factor receptor binding


name: H2O + NAD(+) + octanal = 2 H(+) + NADH + octanoate


name: Formation of the pre-incision complex in GG-NER (Homo sapiens)


name: SGT1:HSP90 binds inactive NLRP3 (Canis familiaris)


name: Translocation of PDK1 to Plasma membrane (Xenopus tropicalis)


name: HIF-alpha translocates from cytosol to nucleus (Xenopus tropicalis)


name: H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+) => (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADH


name: Activation of TAK1 complex bound to activated TLR4 complex (Rattus norvegicus)


name: (1R,2R,3R)-prephytoene diphosphate = 15-cis-phytoene + diphosphate


name: cytidine(1407) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1407) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 2 [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 <=> [thyroglobulin]-dehydroalanine + [thyroglobulin]-L-thyroxine + 2 H2O


name: naphtopyrone YWA1 => H(+) + H2O + norrubrofusarin


name: TCR binds self-lipid-based antigen via CD1 (Gallus gallus)


name: Phosphorylated MAPKs translocate into the nucleus (Drosophila melanogaster)


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Rattus norvegicus)


name: FAS-mediated dimerization of procaspase-8 (Gallus gallus)


name: N-hydroxy-L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Gallus gallus)


name: L-galactonate + NADP(+) <=> aldehydo-D-galacturonate + H(+) + NADPH


name: 2-butyne-1,4-diol + NAD(+) => 4-hydroxy-2-butynal + H(+) + NADH


name: acetyl-CoA + 2 H(+) + 3 malonyl-CoA <=> 3 CO2 + 4 CoA + orsellinate


name: indole-3-pyruvate imine dimer => chromopyrrolate + H(+) + NH4(+)


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADH => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+)


name: 2 L-ascorbate + N-(9Z-octadecenoyl)glycine + O2 <=> H2O + 2 monodehydro-L-ascorbate radical + N-(9Z-octadecenoyl)-(2S)-hydroxyglycine


name: CD320 binds extracellular TCN2:RCbl (Mus musculus)


name: (2S)-2-hydroxy-4-phenylbutanenitrile => 3-phenylpropanal + hydrogen cyanide


name: diphosphate + isoprene => dimethylallyl diphosphate


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Sus scrofa)


name: ADP + D-fructose 6-phosphate + H(+) => ATP + D-fructose


name: (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1R,6S)-isopiperitenol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (3R)-hydroxytetracosanoyl-CoA + NAD(+) => 3-oxotetracosanoyl-CoA + H(+) + NADH


name: DCD forms oligomeric complex (Homo sapiens)


name: (6E)-8-methylnon-6-enoyl-CoA + vanillylamine = capsaicin + CoA + H(+)


name: Interleukin-1 family are secreted (Gallus gallus)


name: The FA anion diffuses away laterally from UCP (Xenopus tropicalis)


name: Further sulfation on galactose residues produces KSPG (Drosophila melanogaster)


name: 3 O2 + obtusifoliol + 3 reduced [NADPH--hemoprotein reductase] = 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Dictyostelium discoideum)


name: 2-methoxy-6-(all-trans-nonaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine => 3-(all-trans-nonaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine


name: ABCB11 transports bile salts from cytosol to extracellular region (Dictyostelium discoideum)


name: beta-amyrin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 11-oxo-beta-amyrin + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: (S)-2-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Sus scrofa)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = (9Z)-octadecenoate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine


name: p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Mus musculus)


name: Recruitment of Telomerase RNP to the Telomeric Chromosome End (Sus scrofa)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Bos taurus)


name: Sequestration of tBID by BCL-2 (Bos taurus)


name: 2-methylbutanoyl-CoA + H2O => 2-methylbutanoate + CoA + H(+)


name: Cu(2+)(out) + L-ascorbate(in) => Cu(+)(out) + H(+) + monodehydro-L-ascorbate radical(in)


name: testosterone + UDP-alpha-D-glucuronate = H(+) + testosterone 17-O-(beta-D-glucuronate) + UDP


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Mus musculus)


name: 4beta-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-4beta,26-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: galactitol + NAD(+) <=> D-galactose + H(+) + NADH


name: Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) (Drosophila melanogaster)


name: D-allo-threonine + H2O + O2 = (R)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+)


name: ADP + coproporphyrin III(out) + H(+) + phosphate => ATP + coproporphyrin III(in) + H2O


name: FGAM + ATP => AIR + ADP + Pi (Danio rerio)


name: Activation of TAK1 complex bound to activated TLR4 complex (Sus scrofa)


name: NADPH + 2 O2 + prefumagillin <=> acetaldehyde + fumagillin + H2O + NADP(+)


name: H2O + L-serine + O2 <=> 3-hydroxypyruvate + H2O2 + NH4(+)


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Homo sapiens)


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Plasmodium falciparum)


name: 5,6-dihydrouracil + H2O <=> 3-(carbamoylamino)propanoate + H(+)


name: benzyl alcohol + NAD(+) => benzaldehyde + H(+) + NADH


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O => n acetate + chitosan


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine


name: TPMT transfers CH3 from AdoMet to 6MP (Bos taurus)


name: TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 (Mus musculus)


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Sus scrofa)


name: 1-acyl LPG is acylated to PG by LPGAT (Canis familiaris)


name: SMAD3 binds STUB1 (CHIP) (Canis familiaris)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Schizosaccharomyces pombe)


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: Condensin II complex binds H4K20me1-containing nucleosomes (Plasmodium falciparum)


name: HSD11B1 hydrogenates PREDN to PREDL in hepatic cell (Mus musculus)


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Rattus norvegicus)


name: adenosine 5'-phosphosulfate + H2O <=> AMP + 2 H(+) + sulfate


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Xenopus tropicalis)


name: (S)-canadine + S-adenosyl-L-methionine <=> (S)-cis-N-methylcanadine + S-adenosyl-L-homocysteine


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Danio rerio)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Canis familiaris)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Dictyostelium discoideum)


name: 3-methylundecanoyl-CoA + AMP + diphosphate => 3-methylundecanoate + ATP + CoA


name: 3'-dephospho-CoA(in) + ADP(out) = 3'-dephospho-CoA(out) + ADP(in)


name: Proteasome mediated degradation of COP1 (Canis familiaris)


name: (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+) => (R)-lanthionine ketimine + 2 H(+) + NADPH


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Mus musculus)


name: PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Mus musculus)


name: 16-epivellosimine + acetyl-CoA <=> CoA + vinorine


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: hexanoyl-CoA + NAD(+) <=> (2E)-hexenoyl-CoA + H(+) + NADH


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: docosanoate + glycerol + H(+) => 1-docosanoylglycerol + H2O


name: a thymidine(6-4)cytidine in DNA => a thymine-cytidine dinucleotide in DNA


name: Activation of TAK1 complex bound to pUb-TRAF6 (Homo sapiens)


name: GDIs block activation of RHOC (Canis familiaris)


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Rattus norvegicus)


name: MTMR12 binds MTM1 (Dictyostelium discoideum)


name: p53 positively regulates transcription of MIR34 microRNAs (Homo sapiens)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Sus scrofa)


name: Na(+)(out) + thymidine(out) <=> Na(+)(in) + thymidine(in)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base <=> a 1,2-diacyl-sn-glycerol + an alpha-D-mannosyl-6-(1D-myo-inositol phospho)-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Sus scrofa)


name: 18-hydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + octadecanoate + reduced [NADPH--hemoprotein reductase]


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Canis familiaris)


name: Activated PCLG1 dissociates from NTRK3 (Sus scrofa)


name: MET bound PI3K generates PIP3 (Rattus norvegicus)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 => (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate


name: ATP + holo-[peptidyl-carrier protein] + L-serine => AMP + diphosphate + L-seryl-[peptidyl-carrier protein]


name: an N-acyl-D-mannosamine => an N-acyl-D-glucosamine


name: pyrimidine nucleoside transmembrane transporter activity


name: 3-oxoeicosasphinganine + H(+) + NADPH => C20 sphinganine + NADP(+)


name: (5Z)-tetradecenoyl-CoA + acetyl-CoA => 3-oxo-(7Z-hexadecenoyl)-CoA + CoA


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Bos taurus)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Bos taurus)


name: coproporphyrinogen III + 2 H(+) + O2 <=> 2 CO2 + 2 H2O + protoporphyrinogen IX


name: an N-acyl-(4R)-4-hydroxysphinganine + CoA + H(+) => (4R)-hydroxysphinganine + a fatty acyl-CoA


name: ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine


name: Glycosylation of Hh (Drosophila melanogaster)


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Gallus gallus)


name: USP19 deubiquitinates RNF123 (Gallus gallus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: 15alpha-stemmadenine + NADP(+) = 15alpha-stemmadenine intermediate II + 2 H(+) + NADPH


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Homo sapiens)


name: dehydroprobetaenone I + H(+) + NADPH + O2 => epoxybetaenone + H2O + NADP(+)


name: ST6GALNAC5,6 transfer Neu5Ac to GM1b (Mus musculus)


name: 2 CO2 + 2 NH4(+) => 3 H(+) + H2O + urea-1-carboxylate


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Schizosaccharomyces pombe)


name: a 1-acyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) => a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2


name: 7-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: ACBD4,5 bind MCFA-CoA and LCFA-CoA (Mus musculus)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Caenorhabditis elegans)


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Canis familiaris)


name: eNOS translocation from Golgi to Caveolae (Saccharomyces cerevisiae)


name: (2Z,6E)-farnesyl diphosphate => diphosphate + gamma-cadinene


name: H2O + N-acetyl-L-phenylalanine <=> acetate + L-phenylalanine


name: SLC6A4 binds TCAs and SSRIs (Drosophila melanogaster)


name: L-homocysteine + L-serine => H2O + L,L-cystathionine


name: NADH + nitrobenzene + O2 => catechol + NAD(+) + nitrite


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Sus scrofa)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Canis familiaris)


name: COQ3 methylates DHDB (Schizosaccharomyces pombe)


name: [calmodulin]-L-lysine + S-adenosyl-L-methionine <=> [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine


name: Caspase-3 cleaves pro-interleukin-16 (Homo sapiens)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Bos taurus)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Sus scrofa)


name: 2-phenylacetaldehyde + H(+) + NADH => 2-phenylethanol + NAD(+)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + AH2 + O2 => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + A + 2 H2O


name: H2O + L-ectoine <=> (2S)-2-acetamido-4-aminobutanoate


name: Exocytosis of secretory granule lumen proteins (Gallus gallus)


name: CYP2D6 4-hydroxylates debrisoquine (Dictyostelium discoideum)


name: B4GALTs transfer Gal to the keratan chain (Homo sapiens)


name: AKT can phosphorylate NR4A1 (NUR77) (Danio rerio)


name: NADP(+) + tetradecanoyl-CoA => (2E)-tetradecenoyl-CoA + H(+) + NADPH


name: CYP1A2 S-demethylates 6MMP (Homo sapiens)


name: 2-(glutathione-S-yl)-hydroquinone + glutathione <=> glutathione disulfide + hydroquinone


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = daturadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E,10E)-geranylgeranyl diphosphate = diphosphate + isoelisabethatriene


name: STAMBPL1 is a deubiquitinase (Schizosaccharomyces pombe)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Mus musculus)


name: PLD6 dimer cleaves primary piRNA transcript to pre-piRNA (Homo sapiens)


name: a ribonucleoside 3',5'-bisphosphate + H2O => a ribonucleoside 5'-phosphate + phosphate


name: AH2 + dehydroprobetaenone I => A + probetaenone I


name: indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP


name: estrone 3-sulfate(out) + pentanoate(in) = estrone 3-sulfate(in) + pentanoate(out)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Bos taurus)


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Bos taurus)


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Gallus gallus)


name: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + ATP + CoA <=> [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + AMP + diphosphate


name: XDH oxidises 6MP to 6TU (Rattus norvegicus)


name: demethylphylloquinone + H(+) + NADPH <=> demethylphylloquinol + NADP(+)


name: dimethyl sulfone + FMNH2 + O2 = FMN + formaldehyde + 2 H(+) + H2O + methanesulfinate


name: KCNJ11:ABCC9 binds nicorandil (Gallus gallus)


name: acetyl-CoA + 9 H(+) + 4 malonyl-CoA + 5 NADPH = 7-methylmellein + 3 CO2 + 5 CoA + 4 H2O + 5 NADP(+)


name: dodecanoyl-[ACP] + H2O <=> dodecanoate + H(+) + holo-[ACP]


name: YWHAB dimer dissociates from dephosphorylated RAF (Caenorhabditis elegans)


name: Plasmin proteolyzes IGF:IGFBP-3:ALS (Homo sapiens)


name: 2-oxophytanate + H2O2 => (2S)-2-hydroxyphytanate + O2


name: CTSL bind CTSL inhibitors (Homo sapiens)


name: 4-phenylbutan-2-one + H(+) + NADH + NH4(+) => 4-phenylbutan-2-amine + H2O + NAD(+)


name: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate


name: Type II receptor phosphorylates type I receptor (Drosophila melanogaster)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Bos taurus)


name: octacosanoyl-CoA + sphinganine => CoA + H(+) + N-(octacosanoyl)-sphinganine


name: TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers bind the ERBB2 gene promoter and recruit YY1 (Homo sapiens)


name: 2-glyceryl-prostaglandin G2 => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2


name: a 3-methyl fatty acyl-CoA + AMP + diphosphate => 3-methyl fatty acid + ATP + CoA


name: 1,25(OH)2D binds VDR (Rattus norvegicus)


name: H2O + N(5)-acyl-L-ornithine ester => an alcohol + H(+) + N(5)-acyl-L-ornithine


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Canis familiaris)


name: RAB43 hydrolyses GTP (Schizosaccharomyces pombe)


name: SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Bos taurus)


name: IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Mus musculus)


name: MECP2 and SOX2 bind MIR137 gene (Homo sapiens)


name: ent-copalyl diphosphate => diphosphate + ent-atiserene


name: D-ribulose 5-phosphate <=> (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)


name: acetyl-CoA + H(+) + malonyl-CoA => acetoacetyl-CoA + CO2 + CoA


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Bos taurus)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Plasmodium falciparum)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Sus scrofa)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Sus scrofa)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Danio rerio)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Canis familiaris)


name: (2S)-2-aminobutanoate + 2-oxo-3-sulfanylpropanoate => 2-oxobutanoate + L-cysteine


name: L-tryptophan = (E)-3-(indol-3-yl)acrylate + NH4(+)


name: glycine betaine-activated nonselective monoatomic cation channel activity


name: (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + O2 + reduced [NADPH--hemoprotein reductase] <=> (20S)-ginsenoside C-K + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of STATs (Canis familiaris)


name: AMP(out) + FAD(in) => AMP(in) + FAD(out)


name: Endostatin degradation by cathepsins (Mus musculus)


name: methanol + NAD(+) => formaldehyde + H(+) + NADH


name: ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi (Drosophila melanogaster)


name: PTK6 phosphorylates CDKN1B (Rattus norvegicus)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Plasmodium falciparum)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Homo sapiens)


name: methanol + N,N-dimethyl-4-nitrosoaniline <=> 4-(hydroxylamino)-N,N-dimethylaniline + formaldehyde


name: Interaction of Nectins with Afadin (Mus musculus)


name: PDGFRs bind type II TKI (Xenopus tropicalis)


name: Conversion of glyoxylate to oxalate (Bos taurus)


name: NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex (Canis familiaris)


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Bos taurus)


name: GSDMD (1-275) binds bacterial cardiolipin (Rattus norvegicus)


name: Proteasome mediated degradation of Cyclin D1 (Drosophila melanogaster)


name: TGFBR3 phosphorylation by TGFBR2 complex (Rattus norvegicus)


name: diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein] => ATP + L-tyrosyl-[protein]


name: D-arabinose(in) + H(+)(in) => D-arabinose(out) + H(+)(out)


name: 5alpha-dihydrotestosterone sulfate(out) + 2 Na(+)(out) => 5alpha-dihydrotestosterone sulfate(in) + 2 Na(+)(in)


name: NAD(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH


name: a ubiquinone + H(+) + NADH = a ubiquinol + NAD(+)


name: 4-aminobutanoate + L-arginine => H2O + N(2)-(4-aminobutanoyl)-L-arginine


name: Lamellar bodies bind the early cornified envelope (Bos taurus)


name: 2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate <=> 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: The ABCC family mediates organic anion transport (Canis familiaris)


name: Phosphorylation of Chk2 by ATM upon DNA damage (Gallus gallus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Mus musculus)


name: (3R)-hydroxyhexadecanoyl-CoA + NAD(+) => 3-oxohexadecanoyl-CoA + H(+) + NADH


name: 5,10-dihydrophenazine 1-carboxylate + O2 = H2O2 + phenazine-1-carboxylate


name: a rhodoquinone + succinate => a rhodoquinol + fumarate


name: Cleavage of uracil by UNG glycosylase (Mus musculus)


name: MAPK12 phosphorylates PTPN3 (Mus musculus)


name: anthocyanin 5-aromatic acyltransferase activity


name: (3R,4S,5S,6R)-pentachlorocyclohexene = (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + chloride + H(+)


name: ATP + GTP => diphosphate + pppA(2'-5')pG


name: Tropoelastin forms aggregate globules (Bos taurus)


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Dictyostelium discoideum)


name: ATP + beta-alanine + tryptamine => AMP + beta-alanyl-tryptamine + diphosphate + H(+)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 => 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate


name: Autocleavage of ESPL1 (Separase) (Caenorhabditis elegans)


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Mus musculus)


name: 2'-O-methyllicodione + H(+) + S-adenosyl-L-homocysteine => licodione + S-adenosyl-L-methionine


name: RAC3 GDIs block activation of RAC3 (Canis familiaris)


name: FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Rattus norvegicus)


name: Recruitment of AP-2 complex and clathrin (Rattus norvegicus)


name: NSF ATPase activity dissociates cis-SNARE (Saccharomyces cerevisiae)


name: Caspase-mediated cleavage of MASK (Xenopus tropicalis)


name: dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Drosophila melanogaster)


name: H(+) + NADH + O2 + protoviolaceinate => H2O + NAD(+) + violaceinate


name: (E)-hexadec-2-enoate(out) + ATP(in) + CoA(in) + H(+)(out) => (2E)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal => beta-cryptoxanthin + O2


name: [thioredoxin]-dithiol + tert-butyl hydroperoxide <=> [thioredoxin]-disulfide + H2O + tert-butanol


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate


name: 2,3-epoxyphylloquinone + 4-carboxy-L-glutamyl-[protein] + H(+) + H2O => CO2 + L-glutamyl-[protein] + O2 + phylloquinol


name: a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-glycerol 3-phosphate


name: Phospholipase C-gamma1 binds to the activated EGF receptor (Gallus gallus)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Rattus norvegicus)


name: ethyl butanoate + H2O + NADP(+) => H(+) + hexan-3-one + NADPH + O2


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Bos taurus)


name: GABRR pentamers:GABA transports extracellular Cl- to cytosol (Drosophila melanogaster)


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Bos taurus)


name: Interaction of Tie2 and Shc1 (Bos taurus)


name: 6-hydroxy-N-methylmyosmine + H2O2 => (R)-6-hydroxynicotine + O2


name: lipopolysaccharide glucosyltransferase II activity


name: The high affinity receptor complex binds to G-protein (Canis familiaris)


name: G alpha (12) binds BTK (Canis familiaris)


name: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) => 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Sus scrofa)


name: D-erythrulose 1-phosphate + H(+) + NADPH => D-erythritol 1-phosphate + NADP(+)


name: MAPK1-dependent phosphorylation of MITF-M (Canis familiaris)


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Caenorhabditis elegans)


name: (2Z,6E)-farnesyl diphosphate <=> beta-bisabolene + diphosphate


name: chloride transmembrane transporter activity


name: ORC1 binds to H4K20me2 (Dictyostelium discoideum)


name: 1,2-dioctanoyl-3-O-beta-D-galactosyl-sn-glycerol + H2O <=> H(+) + octanoate + octanoyl-3-(beta-D-galactosyl)-sn-glycerol


name: ATM phosphorylates RBBP8 (Canis familiaris)


name: Expression of TBX6 in paraxial mesoderm (Homo sapiens)


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Drosophila melanogaster)


name: 1-acyl LPC is acylated to PC by LPCAT (Canis familiaris)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: GPVI binds Fyn and Lyn (Xenopus tropicalis)


name: a 3-oxo-5alpha-steroid + NADP(+) => a 3-oxo-Delta(4)-steroid + H(+) + NADPH


name: CYP79F1 tetrahomomethionine monooxygenase activity


name: a 1-O-alkyl-2-acetyl-sn-glycerol + H(+) + phosphocholine => a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Sus scrofa)


name: beta-alaninamide + H2O => beta-alanine + NH4(+)


name: glyoxylate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine


name: BP180 interacts extracellularly with Laminin 332 (Homo sapiens)


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Gallus gallus)


name: CYP3A4 binds CYP3A4 inhibitors (Bos taurus)


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Drosophila melanogaster)


name: alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose <=> alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: hexadecane + O2 + reduced [NADPH--hemoprotein reductase] = 9-hexadecanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA


name: (2S)-2-hydroxy-3-methylbutanenitrile => 2-methylpropanal + hydrogen cyanide


name: AMP(out) + FMN(in) => AMP(in) + FMN(out)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Canis familiaris)


name: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+) <=> a (3R)-2'-hydroxyisoflavanone + H(+) + NADPH


name: GDP-alpha-D-rhamnose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate <=> alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: ASC binds Caspase-8 complex (Homo sapiens)


name: SOAT1,2 transfer acyl group to CHOL forming CHEST (Homo sapiens)


name: WNT ligands traffic to the Golgi (Homo sapiens)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Danio rerio)


name: Activated PLC gamma dissociates from the PDGF receptor (Canis familiaris)


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Saccharomyces cerevisiae)


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Homo sapiens)


name: a 5'-end phospho-guanosine in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP => a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O


name: CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)


name: 3-oxohexacosanoyl-CoA + H(+) + NADPH = (3R)-hydroxyhexacosanoyl-CoA + NADP(+)


name: (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 3-[(E)-2-isocyanovinyl]indole + 2 CO2 + H2O + succinate


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Drosophila melanogaster)


name: 6-phospho-D-gluconate + NAD(+) <=> 6-phospho-2-dehydro-D-gluconate + H(+) + NADH


name: cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine <=> 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: dehydroabietadienal + H2O + NADP(+) = dehydroabietate + 2 H(+) + NADPH


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Canis familiaris)


name: JMJD1C demethylates H3K9 mono- and di-methylation (Rattus norvegicus)


name: Elastin cross-linking by lysyl oxidase (Rattus norvegicus)


name: Defective GFPT1 does not transfer an amino group from L-Gln to F6P to form GlcN6P (Homo sapiens)


name: E2F1/3:DP1/2 binds NOTCH1 promoter (Homo sapiens)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerol + CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA


name: secretion of WNT ligands (Gallus gallus)


name: L-threo-3-phenylserine => benzaldehyde + glycine


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Homo sapiens)


name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin (Sus scrofa)


name: 2,6-dihydroxybenzoate + H(+) <=> CO2 + resorcinol


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Bos taurus)


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Mus musculus)


name: GDP-alpha-D-mannose + phosphate => alpha-D-mannose 1-phosphate + GDP + H(+)


name: DHFR dimer binds DHFR inhibitors (Homo sapiens)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + S-adenosyl-L-methionine


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Dictyostelium discoideum)


name: 1-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: (3Z)-dodecenoyl-CoA + acetyl-CoA => 3-oxo-(5Z-tetradecenoyl)-CoA + CoA


name: Calmodulin dissociates KRAS4B from the plasma membrane (Caenorhabditis elegans)


name: EIF2AK4 (GCN2) binds tRNA (Homo sapiens)


name: Phosphorylation of p-KIT on Y900 by Src kinases (Rattus norvegicus)


name: Mitochondrial BTD hydrolyses BCTN (Canis familiaris)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa


name: NMT1/2 transfer MYS to GNAT1 (Canis familiaris)


name: decanoyl-AMP + holo-[ACP] = AMP + decanoyl-[ACP] + H(+)


name: 11-beta-hydroxysteroid dehydrogenase [NAD(P)+] activity


name: TCF7L1/TCF7L2/LEF1:CTNNB1 bind the MYC gene (Homo sapiens)


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Xenopus tropicalis)


name: ATP + 2 D-alanine => ADP + D-alanyl-D-alanine + H(+) + phosphate


name: Phosphopantetheine conjugation of the ACP domain of FAS (Canis familiaris)


name: all-trans-retinol + tetradecanoyl-CoA <=> all-trans-retinyl tetradecanoate + CoA


name: FGF2:TGFBR3 binding to GIPC1 (Xenopus tropicalis)


name: MAP3K5 phosphorylates MKK3 and MKK6 (Bos taurus)


name: MTMR14, MTMR3 dephosphorylate PI3P (Dictyostelium discoideum)


name: 3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: MTFMT formylates methionyl-tRNA (Homo sapiens)


name: H2O + L-ascorbate 6-phosphate <=> 3-dehydro-L-gulonate 6-phosphate


name: eicosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 2-hydroxyeicosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: beta-D-galactosyl-(1<->1')-N-hexadecanoylsphinganine + H2O = beta-D-galactose + N-hexadecanoylsphinganine


name: DIT and MIT combine to form triiodothyronine (Canis familiaris)


name: 9-ribosyl-trans-zeatin 5'-phosphate + H2O + NADP(+) => H(+) + N(6)-(dimethylallyl)adenosine 5'-phosphate + NADPH + O2


name: SUMOylation of DDX5 with SUMO1 (Mus musculus)


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Homo sapiens)


name: NADPH transfers electrons to FDXR (Drosophila melanogaster)


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Homo sapiens)


name: Activated FGFR4 phosphorylates PLCG1 (Gallus gallus)


name: an (R)-2-haloacid + H2O => a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: CMP + H(+) + saturated 1-archaetidyl-1D-myo-inositol 3-phosphate => 1D-myo-inositol 3-phosphate + CDP-2,3-bis-O-(phytanyl)-sn-glycerol


name: GRK2 sequesters activated Gq (Caenorhabditis elegans)


name: Hikeshi binds HSP70s:ATP (Saccharomyces cerevisiae)


name: prostaglandin H2 = (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde


name: factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Bos taurus)


name: 2-methylpropanoyl-CoA + H(+) + malonyl-[ACP] <=> 4-methyl-3-oxopentanoyl-[ACP] + CO2 + CoA


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)


name: 3-oxocholan-24-oyl-CoA + NAD(+) <=> 3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Danio rerio)


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Dictyostelium discoideum)


name: CBL ubiquitinates FRS2 and FGFR2 (Drosophila melanogaster)


name: butan-2-one + NADP(+) <=> but-3-en-2-one + H(+) + NADPH


name: CI75 transports from the cytosol to the nucleus (Drosophila melanogaster)


name: D-cysteine(in) + L-alanine(out) => D-cysteine(out) + L-alanine(in)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Gallus gallus)


name: AH2 + dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + O2 => A + dTDP-beta-L-evernitrose + H2O


name: (1R)-(1-hydroxyethyl)phosphonate + O2 <=> acetate + 2 H(+) + phosphate


name: Fe(II)-heme b-[protein] + 2 H(+) + nitrite => Fe(III)-heme b-[protein] + H2O + nitric oxide


name: HP1 alpha binds Histone H3K9(me)3 (Dictyostelium discoideum)


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Rattus norvegicus)


name: H2O + N,N'-diacetylchitobiono-1,5-lactone => H(+) + N,N'-diacetylchitobionate


name: Activated FGFR3:p-SHC1 binds GRB2:SOS1 (Gallus gallus)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Homo sapiens)


name: Interaction of DAP12 and TREM1 (Canis familiaris)


name: phenazine-1-carboxylate + S-adenosyl-L-methionine <=> 5-methyl-phenazine-1-carboxylate + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine => 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: dimethylallyl diphosphate + fumigaclavine A <=> diphosphate + fumigaclavine C


name: 2,6-dichlorobenzoquinone + H2O => 2-chloro-6-hydroxy-1,4-benzoquinone + chloride + 2 H(+)


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Caenorhabditis elegans)


name: luteolin + UDP-alpha-D-glucuronate <=> H(+) + luteolin 7-O-beta-D-glucuronide + UDP


name: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA <=> CoA + N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2]


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Danio rerio)


name: EP2 and EP4 receptors can bind PGE2 (Gallus gallus)


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Mus musculus)


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)


name: ATP + H2O + L-tryptophan <=> AMP + D-tryptophan + diphosphate + H(+)


name: G-protein coupled bile acid receptor binds lithocholic acid (Bos taurus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an N-acylethanolamine + H(+) => H2O + N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: RAC1 and CDC42 activate PAK2 (Dictyostelium discoideum)


name: PGH2 is isomerised to PGD2 by HPGDS (Canis familiaris)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Bos taurus)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Mus musculus)


name: Monoubiquitination of FANCD2:FANCI (Sus scrofa)


name: beta-lactose + O2 => H2O2 + lactobiono-1,5-lactone


name: LTC4 is exported from the cytosol by ABCC1 (Saccharomyces cerevisiae)


name: H(+) + Na(+)(in) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> Na(+)(out) + NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Bos taurus)


name: NOTCH1 t(7;9)(NOTCH1:M1580_K2555) is cleaved to produce NEXT1 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-isoafricanol + diphosphate


name: K11-linked polyubiquitin modification-dependent protein binding


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Xenopus tropicalis)


name: ABCB11 transports bile salts from cytosol to extracellular region (Homo sapiens)


name: (+)-sesamin monocatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) => (+)-sesamin + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n)


name: Binding of STAT1 to p-IFNGR1 (Bos taurus)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Homo sapiens)


name: Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Homo sapiens)


name: CES1trimer hydrolyses ACEI pro-drugs to ACEIs (Dictyostelium discoideum)


name: Conjugation of SUMO1 to UBA2:SAE1 (Xenopus tropicalis)


name: (R)-mevalonate + CoA + 2 NAD(+) <=> (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH


name: 13-dihydrocarminomycin + H(+) + NADPH + O2 = carminomycin + 2 H2O + NADP(+)


name: TRIAP1 binds PRELID1, PRELID3A (Canis familiaris)


name: CYP2A13 oxidises AFM1 to AFM1E (Rattus norvegicus)


name: Formation of hair keratin fibres (Canis familiaris)


name: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) = 3-dehydroquinate + H(+) + NADH + NH4(+)


name: ADP + H(+) + valienone 7-phosphate => ATP + valienone


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Bos taurus)


name: A + H2O + L-alanine + thio-Mo-molybdopterin => AH2 + L-cysteine + Mo-molybdopterin


name: ERCC8 (CSA) binds stalled RNA Pol II (Xenopus tropicalis)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Canis familiaris)


name: pre-VLDL binds lipids to form VLDL (Homo sapiens)


name: SETD9 methylates TP53 (Canis familiaris)


name: Interaction of SIGLEC14/15/16 and DAP12 (Homo sapiens)


name: Fall Back to Closed Pre-initiation Complex (Saccharomyces cerevisiae)


name: all-trans-antheraxanthin + H2O + L-dehydroascorbate => all-trans-violaxanthin + L-ascorbate


name: COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates (Caenorhabditis elegans)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Bos taurus)


name: MEN1 binds MLL2 complex (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base <=> a 1,2-diacyl-sn-glycerol + an inositol phosphomannosylnositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: Association of  PARVA with TESK1 (Gallus gallus)


name: Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine => Mg-protoporphyrin IX + S-adenosyl-L-methionine


name: Molybdenum ion transfer onto molybdopterin (Bos taurus)


name: D-apiitol + NAD(+) => aldehydo-D-apiose + H(+) + NADH


name: chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] = 3,8-divinyl chlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: epothilone D + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => epothilone B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2-acyl LPG is acylated to PG by LPGAT (Caenorhabditis elegans)


name: MSH2:MSH3 binds insertion/deletion loop of 2 bases or more (Saccharomyces cerevisiae)


name: GDP-beta-L-fucose(in) + GMP(out) <=> GDP-beta-L-fucose(out) + GMP(in)


name: α1-antagonists bind ADRA1A,B,D (Caenorhabditis elegans)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Caenorhabditis elegans)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Sus scrofa)


name: an alcohol + H(+) + N(5)-acyl-L-ornithine => H2O + N(5)-acyl-L-ornithine ester


name: PIDD1 translocates to the cytosol (Mus musculus)


name: D-glucono-1,5-lactone + H(+) + NADH => D-glucose + NAD(+)


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Sus scrofa)


name: S-adenosyl-L-homocysteine + S-methyl-L-methionine => L-methionine + S-adenosyl-L-methionine


name: IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Gallus gallus)


name: H(+) + NADH + O2 + propane = H2O + NAD(+) + propan-2-ol


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Mus musculus)


name: USP20, USP33 deubiquitinate ADRB2 (Xenopus tropicalis)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst) (Mus musculus)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Rattus norvegicus)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Sus scrofa)


name: H2O + N-formimidoyl-L-glutamate => N-formyl-L-glutamate + NH4(+)


name: 3'-ketolactose + H2O => 3-keto-beta-D-galactose + beta-D-glucose


name: p-MAPK2/3 phosphorylates HSP27 (Bos taurus)


name: H2O + sn-glycero-3-phospho-(1'-rac-glycerol) <=> glycerol + H(+) + sn-glycerol 3-phosphate


name: (2E,11Z)-octadecadienoyl-CoA + H2O => (R)-3-hydroxy-(11Z)-octadecenoyl-CoA


name: S-adenosyl-L-methionine + TRIBOA beta-D-glucoside => DIMBOA beta-D-glucoside + H(+) + S-adenosyl-L-homocysteine


name: a purine 2'-deoxy-D-ribonucleoside + phosphate <=> 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase


name: PDPK1 phosphorylates PKN1,2,3 (Drosophila melanogaster)


name: 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 H2O => 2 AMP + ATP + 2 H(+)


name: (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+) => 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + NADPH


name: F0 is cleaved, releasing F1, F2, F(110-136) (Homo sapiens)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Schizosaccharomyces pombe)


name: (2E,6E)-farnesyl diphosphate = diphosphate + viridiflorene


name: 17-hydroxylupanine + 2 Fe(II)-[cytochrome c] + 2 H(+) => 2 Fe(III)-[cytochrome c] + H2O + lupanine


name: quillaic acid 28-beta-D-glucoside + UDP => quillate + UDP-alpha-D-glucose


name: YWHAB dimer dissociates from KSR1:MARK3 (Bos taurus)


name: IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Homo sapiens)


name: Caspase-mediated cleavage of plakophilin-1 (Homo sapiens)


name: H2O + norlichexanthone => 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + H(+)


name: misfolded CFTR is degraded by the 26S proteasome (Bos taurus)


name: 2xTPK1:Mg2+ phosphorylates THMN (Saccharomyces cerevisiae)


name: S1PR1 binds S1PR1 agonists (Rattus norvegicus)


name: ADP + alpha-D-ribose 1-phosphate => alpha-D-ribose 1,5-bisphosphate + AMP + H(+)


name: 1D-myo-inositol 1,4,5-trisphosphate + ATP => 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + H(+)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate => 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O


name: (2E,6E)-farnesyl diphosphate + H2O <=> (2E,6E)-hedycaryol + diphosphate


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> 1,4-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Drosophila melanogaster)


name: MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) (Rattus norvegicus)


name: active borate transmembrane transporter activity


name: Collagen type I degradation by MMP15 (Rattus norvegicus)


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Sus scrofa)


name: VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization (Mus musculus)


name: decanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-decenoyl-CoA + reduced [electron-transfer flavoprotein]


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-mannosamine => 3 H(+) + 2 NADH + UDP-N-acetyl-alpha-D-mannosaminouronate


name: butanoate(out) + estrone 3-sulfate(in) = butanoate(in) + estrone 3-sulfate(out)


name: ATP + L-threonine + tRNA(Thr) => AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)


name: IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Gallus gallus)


name: EPCAM binds itself to form homotypic cell adhesion (Xenopus tropicalis)


name: 5-methylcytidine(2870) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(2870) in 25S rRNA + S-adenosyl-L-methionine


name: (E)-feruloyl-CoA + H2O <=> acetyl-CoA + vanillin


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Mus musculus)


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Xenopus tropicalis)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Homo sapiens)


name: p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Homo sapiens)


name: 17-O-acetylajmaline + H2O <=> acetate + ajmaline + H(+)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Bos taurus)


name: 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA <=> 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: (2S)-naringenin + S-adenosyl-L-methionine <=> (2S)-naringenin 4'-methyl ether + H(+) + S-adenosyl-L-homocysteine


name: 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Homo sapiens)


name: GAB1 recruits CRK,CRKL to MET (Caenorhabditis elegans)


name: H2O + L-alaninamide <=> L-alanine + NH4(+)


name: [thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite => 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Xenopus tropicalis)


name: 3-hydroxy-3-methylglutarate + CoA + H(+) => (3S)-hydroxy-3-methylglutaryl-CoA + H2O


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 <=> (8R)-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate


name: H2O + L-cysteinyl-tRNA(Pro) = H(+) + L-cysteine + tRNA(Pro)


name: CYB5Rs reduce MetHb to HbA (Mus musculus)


name: CETP-mediated lipid exchange: spherical HDL gains triacylglycerol (Homo sapiens)


name: CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Rattus norvegicus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA => 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA


name: 2-aminomuconate 6-semialdehyde + H2O + NAD(+) = (2Z,4E)-2-aminomuconate + 2 H(+) + NADH


name: Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol (Homo sapiens)


name: a carboxylate(in) + nicotinate(out) => a carboxylate(out) + nicotinate(in)


name: TFAP2C translocates to the nucleus (Rattus norvegicus)


name: p-3Y-SHC1 dissociates from IGF1R (Bos taurus)


name: p-S276-RELA binds RELB (Rattus norvegicus)


name: 1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Gallus gallus)


name: FANCD2 binds FANCI (Dictyostelium discoideum)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine => 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA


name: CUL3:RBX1 ubiquitinates KEAP1 (Dictyostelium discoideum)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O <=> a 1-acyl-sn-glycero-3-phosphate + a fatty acid + H(+)


name: 12-oxo-leukotriene B4 + H(+) + NADH = 12-oxo-(5S)-hydroxy-(6Z,8E,14Z)-eicosatrienoate + NAD(+)


name: [beta-adrenergic receptor]-phosphate + ADP + H(+) => [beta-adrenergic receptor] + ATP


name: calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration


name: (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Rattus norvegicus)


name: (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: CES1,CES2 hydrolyze ASA- to ST (Gallus gallus)


name: SIRT4 cleaves lipoyl from DLAT (Drosophila melanogaster)


name: Dissociation of HSF1:HSP90 complex in the nucleus (Schizosaccharomyces pombe)


name: Furin cleaves pro-factor VII to factor VII (Bos taurus)


name: 2,4-dichlorobenzoyl-CoA + NADPH => 4-chlorobenzoyl-CoA + chloride + NADP(+)


name: 2 glyoxylate + H(+) <=> 2-hydroxy-3-oxopropanoate + CO2


name: gossypetin 8-methyl ester 3'-O-methyltransferase activity


name: homogentisate + O2 => 4-maleylacetoacetate + H(+)


name: 4 H(+) + 4 nitrite => 2 H2O + 4 nitric oxide + O2


name: (E)-anol + S-adenosyl-L-methionine => (E)-anethole + H(+) + S-adenosyl-L-homocysteine


name: ALDH8A1 oxidises 9cRAL to 9cRA (Dictyostelium discoideum)


name: JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Bos taurus)


name: adenosine + O2 = 5'-dehydroadenosine + H2O2


name: hydrogen cyanide + propanal => (2S)-2-hydroxybutanenitrile


name: (E)-4-hydroxynon-2-enal + H(+) + NADH => (E)-4-hydroxynon-2-en-1-ol + NAD(+)


name: 1-O-(trans-4-coumaroyl)-beta-D-glucose + cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) betaine => beta-D-glucose + cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside] + H(+)


name: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity


name: 17-hydroxy-3-oxochol-4-en-22-oyl-CoA => androst-4-ene-3,17-dione + propanoyl-CoA


name: Persulfide sulfur is dioxygenated (Homo sapiens)


name: H(+) + 2 H2O2 + hexadecanoate = CO2 + 3 H2O + pentadecanal


name: 3 a menaquinol + protoporphyrin IX => 3 a menaquinone + protoporphyrinogen IX


name: Furin cleaves pro-protein C to protein C (Mus musculus)


name: FOXF1 binds the GATA4 gene (Homo sapiens)


name: (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + NADP(+) => (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H(+) + NADPH


name: PHGDH tetramer dehydrogenates 3PG (Sus scrofa)


name: p-S54-PDE4B hydrolyses cAMP (Homo sapiens)


name: (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H(+) + NADH => (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + NAD(+)


name: Change of PKC theta conformation (Bos taurus)


name: 11-cis-retinol + H(+) + hexadecanoate => 11-cis-retinyl hexadecanoate + H2O


name: a 5'-end 5'-phospho-ribonucleoside-RNA + S-adenosyl-L-methionine <=> a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine


name: (25R)-cholest-5-ene-3beta,26-diol + H2O + 2 oxidized [adrenodoxin] => cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)


name: ATP + L-threonyl-[myosin heavy-chain] <=> ADP + H(+) + O-phospho-L-threonyl-[myosin heavy-chain]


name: emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity


name: 18-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase]


name: p-T774-PKN1 binds CDC25C (Drosophila melanogaster)


name: glycyl-L-leucine(out) + 2 H(+)(out) <=> glycyl-L-leucine + 2 H(+)(in)


name: 3',5'-cyclic GMP(out) + a dicarboxylate(in) = 3',5'-cyclic GMP(in) + a dicarboxylate(out)


name: DNA nucleases unhook the interstrand crosslink (ICL) (Bos taurus)


name: dTDP-alpha-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH


name: 7-methyl-3-oxooct-6-enoyl-CoA + acetate => 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Saccharomyces cerevisiae)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + N-(acetyl)-sphing-4-enine


name: 3-hydroxyisopentadecanoyl-CoA + NADP(+) => 3-oxoisopentadecanoyl-CoA + H(+) + NADPH


name: glucose-6-phosphate dehydrogenase (coenzyme F420) activity


name: PAN2-PAN3 complex partially deadenylates mRNA (Canis familiaris)


name: Coumarin is 7-hydroxylated by CYP2A13 (Danio rerio)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Mus musculus)


name: MESP1 binds the NKX2-5 gene (Homo sapiens)


name: PHF8 demethylates MeK21-histone H4 (Caenorhabditis elegans)


name: 2 H2O2 => O2 + 2 H2O (Schizosaccharomyces pombe)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Xenopus tropicalis)


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Xenopus tropicalis)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Homo sapiens)


name: cAMP degradation by Phosphodiesterases (Danio rerio)


name: GDP-alpha-D-rhamnose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2


name: C1r activates C1s component within C1 complement complex (Gallus gallus)


name: diphosphate + nonanoyl-AMP => ATP + H(+) + nonanoate


name: 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: Activation of PAKs by RAC1 and CDC42 (Xenopus tropicalis)


name: c-src associates with Cx43 in gap junctions (Rattus norvegicus)


name: 5-deoxy-D-ribulose 1-phosphate <=> acetaldehyde + dihydroxyacetone phosphate


name: Binding of SHC1 to insulin receptor (Homo sapiens)


name: 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NAD(+) = 5alpha-cholest-8-en-3-one + CO2 + NADH


name: NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Rattus norvegicus)


name: an N-acyl-sphingoid base + UDP-alpha-D-galactose => a D-galactosylceramide + H(+) + UDP


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Xenopus tropicalis)


name: H2O + TTP = 5-methyl-UMP + diphosphate + H(+)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-taurine


name: Interaction of NCAM1 with Neurocan (Homo sapiens)


name: FRS2 is phosphorylated by active TrkA receptor (Bos taurus)


name: The receptor:G-protein complex dissociates (Bos taurus)


name: 2 dimethylallyl diphosphate <=> (R)-lavandulyl diphosphate + diphosphate


name: D-tyrosine + tRNA(Tyr) => D-tyrosyl-tRNA(Tyr) + H2O


name: Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) (Homo sapiens)


name: FLVCR1-1 transports heme from cytosol to extracellular region (Bos taurus)


name: MTORC1 dissociates from ULK complex (Rattus norvegicus)


name: a 1,3-diacyl-sn-glycerol + H2O <=> a fatty acid + a monoacylglycerol + H(+)


name: SUMOylation of DDX5 with SUMO1 (Caenorhabditis elegans)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> an N-acyl-sphingoid base + lactose


name: (R)-lanthionine ketimine + 2 H(+) + NADPH <=> (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+)


name: an all-trans-retinyl ester + H2O => a fatty acid + all-trans-retinol + H(+)


name: Digestion of diacylglycerols by extracellular PTL:colipase (Mus musculus)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA => (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: CDC42 GDIs block activation of CDC42 (Rattus norvegicus)


name: Phosphorylation of Cyclin B1 in the CRS domain (Xenopus tropicalis)


name: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate + 2 H(+)


name: Activation of SHP2 through the binding to phospho-Gab1 (Mus musculus)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Danio rerio)


name: an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + N-acetyl-D-galactosamine => an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O


name: dihydroxyacetone + phosphoenolpyruvate => dihydroxyacetone phosphate + pyruvate


name: CBP and p300 binds NF-kB complex (Drosophila melanogaster)


name: SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids (Homo sapiens)


name: 4-hydroxybenzoyl-5'-AMP + holo-[4-hydroxyphenylalkanoate synthase] = 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + H(+)


name: biotin(out) + 2 Na(+)(out) <=> biotin(in) + 2 Na(+)(in)


name: KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) (Homo sapiens)


name: 2-dehydro-3-deoxy-L-galactonate + NAD(+) => 3-deoxy-D-glycero-2,5-hexodiulosonate + H(+) + NADH


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Mus musculus)


name: a 2-demethylmenaquinol + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+)


name: NTPDase8 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate


name: SYVN1 ubiquitinates Hh C-terminal fragments (Mus musculus)


name: NRXNs bind NLGNs (Drosophila melanogaster)


name: (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (E)-phenylacetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase]


name: N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: EPS15 and HGS bind ubiquitinated MET (Canis familiaris)


name: a ganglioside GA1 + GDP-beta-L-fucose = a ganglioside Fuc-GA1 + GDP + H(+)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Canis familiaris)


name: (R)-carnitine(out) + O-hexadecanoyl-(R)-carnitine(in) <=> (R)-carnitine(in) + O-hexadecanoyl-(R)-carnitine(out)


name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor


name: p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Plasmodium falciparum)


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Sus scrofa)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Bos taurus)


name: dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Mus musculus)


name: Interaction of PECAM-1 and SHP-1 (Homo sapiens)


name: CBL ubiquitinates FRS2 and FGFR3 (Homo sapiens)


name: RAB43:GTP binds USP8NL (Schizosaccharomyces pombe)


name: asperlicin E + H2O + NADP(+) => asperlicin C + H(+) + NADPH + O2


name: ATP + glutathione + spermidine = ADP + glutathionylspermidine + H(+) + phosphate


name: KAT6A and PML bind TP53 (Canis familiaris)


name: (+)-dehydrodiconiferyl acid + 2 a quinone + H2O = (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Canis familiaris)


name: AMOT proteins bind WWTR1 (TAZ) (Rattus norvegicus)


name: GLUT7 and GLUT11 transport glucose and fructose (Saccharomyces cerevisiae)


name: SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Bos taurus)


name: 7-oxo-25-hydroxycholesterol + H(+) + NADPH => 7beta-25-dihydroxycholesterol + NADP(+)


name: SUMOylation of DNMT3B with SUMO1 (Sus scrofa)


name: 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: Autophosphorylation of LTK dimer:ALKAL1,2 (Homo sapiens)


name: Diacylgycerol activates Protein kinase C, alpha type (Sus scrofa)


name: D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate => D-tagatofuranose 1,6-bisphosphate


name: FAR1 reduces PalmCoA to HXOL (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + alpha-muricholate = adenosine 3',5'-bisphosphate + alpha-muricholate 7-sulfate + H(+)


name: atRAL is reduced to atROL (Mus musculus)


name: N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: acetyl-CoA + N-terminal L-alanyl-[ribosomal protein uS5] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein uS5]


name: myricetin + UDP-alpha-D-glucose => H(+) + myricetin 3-O-beta-D-glucoside + UDP


name: Activated FGFR3 phosphorylates PLCG1 (Mus musculus)


name: PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Rattus norvegicus)


name: UBA1 adenylates ubiquitin in the nucleoplasm (Canis familiaris)


name: SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Bos taurus)


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Rattus norvegicus)


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Canis familiaris)


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Bos taurus)


name: 2-aminopropan-1-ol + H2O + NAD(+) => H(+) + hydroxyacetone + NADH + NH4(+)


name: p-Y705-STAT3 binds p-Y693-STAT4 (Xenopus tropicalis)


name: (9Z)-hexadecenoate + ethanolamine => H2O + N-(9Z-hexadecenoyl) ethanolamine


name: ATP + H2O + sn-glycerol 3-phosphate(out) <=> ADP + H(+) + phosphate + sn-glycerol 3-phosphate(in)


name: 2 H(+) + S-adenosyl-L-homocysteine + wybutosine(37) in tRNA(Phe) => 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + CO2 + S-adenosyl-L-methionine


name: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively (Gallus gallus)


name: Trafficking of GluR1-containing  AMPA receptors (Homo sapiens)


name: H2O + L-arginine + NADP(+) = 5-guanidino-2-oxopentanoate + H(+) + NADPH + NH4(+)


name: CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)


name: 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein]


name: isoliquiritigenin + S-adenosyl-L-methionine <=> 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine


name: P4HB:4-Hyp collagen propeptides dissociates (Caenorhabditis elegans)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Homo sapiens)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Drosophila melanogaster)


name: a quinone + H2O + nitrite => a quinol + nitrate


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Drosophila melanogaster)


name: Serine phosphorylation of STATs (Canis familiaris)


name: acetyl-CoA + ATP + cytidine(34) in elongator tRNA(Met) + H2O = ADP + CoA + H(+) + N(4)-acetylcytidine(34) in elongator tRNA(Met) + phosphate


name: IL22 binds IL22RA1:JAK1 receptor complex (Bos taurus)


name: 4-chlorobenzoate + ATP + CoA => 4-chlorobenzoyl-CoA + AMP + diphosphate


name: CDP-ethanolamine + diphosphate => CTP + H(+) + phosphoethanolamine


name: L-fucose(out) + 2 Na(+)(out) = L-fucose(in) + 2 Na(+)(in)


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Caenorhabditis elegans)


name: CX3 complex formation (Xenopus tropicalis)


name: 3-phenylpyruvate + L-kynurenine => H2O + kynurenate + L-phenylalanine


name: H(+) + H2O + hnu + oxidized dinoflagellate luciferin => dinoflagellate luciferin + O2


name: ERBB4 forms heterodimers with ERBB3 (Canis familiaris)


name: IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Gallus gallus)


name: beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + H(+) + UDP => N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose


name: Interaction of Tie2 and p85 of PI3K (Danio rerio)


name: HTR1A binds HTR1A antagonists (Mus musculus)


name: SUMOylation of HDAC2 with SUMO1 (Bos taurus)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: ADP + D-glucose <=> AMP + D-glucose 6-phosphate + H(+)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Canis familiaris)


name: MAOA inhibitors bind MAOA:FAD (Canis familiaris)


name: 3-oxobutanoyl-[ACP] + CO2 + holo-[ACP] => acetyl-[ACP] + H(+) + malonyl-[ACP]


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Caenorhabditis elegans)


name: a 17-oxo steroid + H(+) + NADPH => a 17beta-hydroxy steroid + NADP(+)


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Sus scrofa)


name: (2S)-2-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + malonyl-CoA = (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + CO2 + CoA


name: ADP + H(+) + oxaloacetate + phosphate => ATP + hydrogencarbonate + pyruvate


name: PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Drosophila melanogaster)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Dictyostelium discoideum)


name: ILK interacts with beta-1 integrin (Mus musculus)


name: Association of ADAM and B4GALT1 With ZP3 (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O


name: (3S,5S)-carbapenam-3-caboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapenem-3-carboxylate + CO2 + H2O + succinate


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Mus musculus)


name: Stalling of DNA replication fork and RPA binding (Canis familiaris)


name: GDP + methylglyoxal <=> N(2)-(1-hydroxy-2-oxopropyl)-GDP


name: C3G stimulates nucleotide exchange on Rap1 (Bos taurus)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Rattus norvegicus)


name: LONP1 degrades mitochondrial matrix proteins (Schizosaccharomyces pombe)


name: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine <=> (+)-pisatin + H(+) + S-adenosyl-L-homocysteine


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycerol + H(+) + phosphoethanolamine


name: [thioredoxin]-disulfide + H(+) + NADPH => [thioredoxin]-dithiol + NADP(+)


name: FAD attaches to SDHA (Caenorhabditis elegans)


name: (2E)-hexenoyl-CoA + H2O => (3S)-hydroxyhexanoyl-CoA


name: D-xylono-1,5-lactone + H2O = D-xylonate + H(+)


name: N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: H(+) + H2O + holo-[ACP] + salicylmethyloxazolinyl-[peptidyl-carrier protein] => L-threonyl-[peptidyl-carrier protein] + salicyl-[ACP]


name: p-S MAPKAPK5 phosphorylates HSPB1 (Bos taurus)