name: Dephosphorylation of JAK1 by SHP1 (Canis familiaris)


name: BCL2 binds BCL2 antagonists (Homo sapiens)


name: IL12RB1:TYK2 binds IL12RB2:JAK2 (Homo sapiens)


name: Association of Ku heterodimer with ends of DNA double-strand breaks (Gallus gallus)


name: FH tetramer hydrates fumarate to L-malate (Homo sapiens)


name: SUMOylation of NFKB2 with SUMO1 (Homo sapiens)


name: (20R,22R)-20,22-dihydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 4-methylpentanal + 2 H2O + 2 oxidized [adrenodoxin] + pregnenolone


name: Expression of IL4,IL13-downregulated extracellular genes (Homo sapiens)


name: N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6)-dimethyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Sus scrofa)


name: PAK1-3 dimer disassociates (Drosophila melanogaster)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Drosophila melanogaster)


name: 26S proteasome processes p-7S-p100:RELB to form p52:RELB (Sus scrofa)


name: Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B (Sus scrofa)


name: [LarE protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine => [LarE protein]-dehydroalanine + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Dictyostelium discoideum)


name: Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)


name: POLD,POLE binds deISGylated PCNA after TLS (Caenorhabditis elegans)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Rattus norvegicus)


name: JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Homo sapiens)


name: SLC16A10-mediated uptake of aromatic amino acids (Dictyostelium discoideum)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Saccharomyces cerevisiae)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Mus musculus)


name: RABGGTA binds RABGGTB (Drosophila melanogaster)


name: Furin cleaves pro-protein C to protein C (Sus scrofa)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Xenopus tropicalis)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Bos taurus)


name: KCNK dimers transport K+ from cytosol to extracellular region (Homo sapiens)


name: TDG excises 5-formylcytosine (Xenopus tropicalis)


name: H2O + paraoxon = 4-nitrophenol + diethylphosphate + 2 H(+)


name: (2E,6E)-farnesyl diphosphate => (+)-guaia-6,9-diene + diphosphate


name: second spliceosomal transesterification activity


name: Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)


name: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Dictyostelium discoideum)


name: ABCB4 transports PC from plasma membrane to extracellular region (Rattus norvegicus)


name: NPHP4 protein binds LATS proteins (Homo sapiens)


name: RCC1 stimulates GDP to GTP exchange on RAN (Gallus gallus)


name: isoorientin + S-adenosyl-L-methionine <=> H(+) + isoscoparin + S-adenosyl-L-homocysteine


name: CALCR binds erenumab (Rattus norvegicus)


name: NGF homodimer binds to p75NTR (Bos taurus)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Xenopus tropicalis)


name: COX15 transforms heme O to heme A (Canis familiaris)


name: 5alpha-androstan-3,17-dione + NADP(+) => androst-4-ene-3,17-dione + H(+) + NADPH


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Homo sapiens)


name: dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H(+) + NADPH => dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP(+)


name: (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate <=> (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate


name: H(+) + N-carbamoyl-2-oxoglycine + NADH => (S)-ureidoglycolate + NAD(+)


name: oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor


name: (5R)-carbapenem-3-carboxylate + CO2 + H2O + succinate => (3S,5S)-carbapenam-3-caboxylate + 2-oxoglutarate + O2


name: Formation of hydroxylysyl-pyrrole cross-links (Caenorhabditis elegans)


name: LONP1 binds mitochondrial matrix proteins (Gallus gallus)


name: kaempferol + UDP-alpha-D-xylose => H(+) + kaempferol 3-O-beta-D-xyloside + UDP


name: a very-long-chain 3-oxoacyl-CoA + H(+) + NADH => a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O => acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative


name: Connexin 36 mediated neuronal gap junction communication (Xenopus tropicalis)


name: LTBP4 binds TGF-Beta-1 (Canis familiaris)


name: Ligand-independent dimerization of FLT3 fusion proteins (Homo sapiens)


name: 2 H(+) + hexadecanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (4Z)-hexadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Formation of TSC1:TSC2 complex (Sus scrofa)


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Gallus gallus)


name: AXIN is phosphorylated in the destruction complex (Mus musculus)


name: platelet-derived growth factor receptor binding


name: 6-phospho-D-gluconate <=> 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O


name: 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O = (9Z)-octadecenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+)


name: TRPA1 tetramer binds TRPA1 antagonists (Drosophila melanogaster)


name: Phosphorylated ERF translocates to the cytosol (Mus musculus)


name: Calmodulin activates Cam-PDE 1 (Bos taurus)


name: a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate => an alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Saccharomyces cerevisiae)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP + CoA = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: Formation of hydroxylysyl-pyridinoline cross-links (Gallus gallus)


name: a ganglioside GM1 + H(+) + UDP => a ganglioside GM2 + UDP-alpha-D-galactose


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + AH2 + S-adenosyl-L-methionine => 5'-deoxyadenosine + 5-hydroxybenzimidazole + A + formate + 2 H(+) + L-methionine + NH4(+) + phosphate


name: Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Bos taurus)


name: XIAP dissociates from ub-TLE (Homo sapiens)


name: Internalization of receptor bound antigen into clathrin coted vesicles (Mus musculus)


name: adenosine 3',5'-bisphosphate + an alkyl sulfate + H(+) => 3'-phosphoadenylyl sulfate + an alcohol


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2 <=> (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa


name: IL35 binds IL27RA:IL12RB2 receptor (Homo sapiens)


name: 3-oxopropanoate + CoA + NADP(+) <=> H(+) + malonyl-CoA + NADPH


name: GDE1 hydrolyzes GroPIns (Caenorhabditis elegans)


name: a fatty acyl-CoA + phytol => a fatty acid phytyl ester + CoA


name: all-trans-retinol + an acyl-CoA => an all-trans-retinyl ester + CoA


name: decanoate + 2 H(+) + NADH => decanal + H2O + NAD(+)


name: ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 (Homo sapiens)


name: IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Canis familiaris)


name: (22S)-22-hydroxysitosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + sitosterol


name: SERPINA5 binds activated protein C (Sus scrofa)


name: MEOS oxidizes ethanol to acetaldehyde (Caenorhabditis elegans)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Canis familiaris)


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Drosophila melanogaster)


name: PHGDH tetramer dehydrogenates 3PG (Drosophila melanogaster)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Xenopus tropicalis)


name: β1,2-agonists bind ADRB1,2 (Homo sapiens)


name: 2 Na(+)(in) + pregnenolone sulfate(in) => 2 Na(+)(out) + pregnenolone sulfate(out)


name: FN1 dimerizes (Dictyostelium discoideum)


name: LRRC16A binds F-actin capping protein (Canis familiaris)


name: CYP11A1 cleaves 20a,22b-DHCHOL (Bos taurus)


name: NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)


name: HPO dimer binds to SAV (Drosophila melanogaster)


name: UNG glycosylase mediated recognition and binding of a 5-hydroxyuracil opposite to a guanine (Homo sapiens)


name: benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Mus musculus)


name: 2-deoxy-D-gluconate + NAD(+) = 3-dehydro-2-deoxy-D-gluconate + H(+) + NADH


name: ARC binds DNM2 and SH3GL3 (Homo sapiens)


name: RAS GAPs stimulate RAS GTPase activity (Rattus norvegicus)


name: 3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde


name: Activated FGFR4 mutants phosphorylate FRS2 (Homo sapiens)


name: H(+)(out) + methotrexate(out) => H(+)(in) + methotrexate(in)


name: Ca impermeable AMPA receptor ligand binding (Drosophila melanogaster)


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Sus scrofa)


name: 2 chloride(out) + sulfate(in) => 2 chloride(in) + sulfate(out)


name: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH => 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O


name: H2O + N,N'-diacetylchitobiose = 2 N-acetyl-D-glucosamine


name: H(+) + L-arginine + NADPH + O2 = H2O + N(omega)-hydroxy-L-arginine + NADP(+)


name: Recruitment and activation of Cdk5 (Homo sapiens)


name: [chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity


name: ABCC1 transports cytosolic RCbl to extracellular region (Caenorhabditis elegans)


name: Activated FGFR2 binds SHC1 (Rattus norvegicus)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 => N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-glycine


name: 6-phospho-D-gluconate + H(+) => 6-phospho-D-glucono-1,5-lactone + H2O


name: 4-epi-eremophilene-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-epi-eremophilene + O2 + reduced [NADPH--hemoprotein reductase]


name: NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Bos taurus)


name: E2F6.com-1 complex binds the E2F1 gene promoter (Homo sapiens)


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Homo sapiens)


name: ADP + an L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A


name: SPRY2 translocates to the plasma membrane (Rattus norvegicus)


name: HOXB1 gene is transcribed (Homo sapiens)


name: (5E)-tetradecenoyl-(R)-carnitine + CoA => (5E)-tetradecenoyl-CoA + (R)-carnitine


name: GPVI stimulates PI3K beta, gamma (Canis familiaris)


name: Expression of Aryl Hydrocarbon receptor-interacting protein (Homo sapiens)


name: NTPDase7 hydrolyzes nucleoside triphosphates (Sus scrofa)


name: Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Danio rerio)


name: N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: EXA4 is converted to EXC4 by LTC4S (Sus scrofa)


name: LMF1,2 transport LIPC dimer from ER lumen to extracellular region (Xenopus tropicalis)


name: (1S,5R)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase]


name: SCUBE1, SCUBE3 oligomerize (Xenopus tropicalis)


name: dihydrobisanhydrobacterioruberin + diphosphate => dimethylallyl diphosphate + H2O + isopentenyldehydrorhodopin


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 => A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O


name: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate <=> (2Z,6E,10E)-geranylgeranyl diphosphate + diphosphate


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Danio rerio)


name: H2O + tetracosanoyl-CoA => CoA + H(+) + tetracosanoate


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Sus scrofa)


name: 3,3',5'-O-trimethylmyricetin + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + syringetin


name: L-cysteine(in) + L-methionine(out) => L-cysteine(out) + L-methionine(in)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate => (E)-gamma-bisabolene + diphosphate


name: 4-methylsulfanyl-2-oxobutanoate + L-glutamate => 2-oxoglutarate + L-methionine


name: DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Rattus norvegicus)


name: glucuronate acceptor + UDP-alpha-D-glucuronate <=> acceptor beta-D-glucuronoside + H(+) + UDP


name: nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs (Homo sapiens)


name: Fibronectin degradation by MMP10 (Homo sapiens)


name: FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Sus scrofa)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Sus scrofa)


name: CFTR transits to the plasma membrane (Xenopus tropicalis)


name: SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Gallus gallus)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Rattus norvegicus)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Bos taurus)


name: HEY1 gene expression is positively regulated by NOTCH3 and STAT1 (Homo sapiens)


name: Dissociation of p-T,Y-MAPK3:MAP2K1 (Caenorhabditis elegans)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Caenorhabditis elegans)


name: 8-oxo-dGTP + H2O = 8-oxo-dGMP + diphosphate + H(+)


name: PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins (Xenopus tropicalis)


name: PPP5C dephosphorylates TP53BP1 (Mus musculus)


name: Interaction of other adapter proteins with p-KIT (Mus musculus)


name: fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Rattus norvegicus)


name: 2-oxoglutarate(in) + 2-oxoheptanedioate(out) => 2-oxoglutarate(out) + 2-oxoheptanedioate(in)


name: palmitoleic acid delta 12 desaturase activity


name: PEX19:class I PMP binds PEX3 (Caenorhabditis elegans)


name: DOCK3 activates RAC1 (Rattus norvegicus)


name: 8-oxo-dATP + H2O <=> 8-oxo-dAMP + diphosphate + H(+)


name: (R)-4'-phosphopantothenate + ATP + L-cysteine => AMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine


name: Autocatalytic activation of bound proMMP2 (Danio rerio)


name: 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+) => H2O + sepiapterin


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Sus scrofa)


name: 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH => 3-deoxyglucosone + H2O + NAD(+)


name: thyroid-stimulating hormone receptor activity


name: TRADD:TRAF2:RIP1 complex binds FADD (Bos taurus)


name: Factor D cleaves C3(H2O)-bound Factor B (Sus scrofa)


name: 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + H(+) + S-adenosyl-L-homocysteine => C30 botryococcene + S-adenosyl-L-methionine


name: p-Y389,400-RUFY1 binds PI3P (Rattus norvegicus)


name: ADP + glutathione(out) + glycoursodeoxycholate(out) + H(+) + phosphate => ATP + glutathione(in) + glycoursodeoxycholate(in) + H2O


name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Sus scrofa)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone <=> 2-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PIAS1 binds p-STAT1 dimer (Mus musculus)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Mus musculus)


name: H2O + O2 + spermine = 3-aminopropanal + H2O2 + spermidine


name: Haptoglobin binds Hemoglobin (Rattus norvegicus)


name: castasterone + O2 + reduced [NADPH--hemoprotein reductase] = brassinolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Dictyostelium discoideum)


name: AMP + diphosphate + long-chain fatty acyl-[mycocerosate synthase] => a long-chain fatty acid + ATP + holo-[mycocerosate synthase]


name: PDE3A inhibitors bind PDE3A (Mus musculus)


name: PTGS2 dimer binds PTGS2 inhibitors (Canis familiaris)


name: dihydroxyacetone phosphate + hexadecanoyl-CoA = 1-hexadecanoylglycerone 3-phosphate + CoA


name: DAAM1 recruits GTP-bound RHOA (Homo sapiens)


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Rattus norvegicus)


name: B3GAT dimers transfer GlcA to tetrasaccharide linker (Homo sapiens)


name: L-pentahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (E)-8-(methylsulfanyl)octanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: a 1-acyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: (2E,6E)-farnesyl diphosphate => alpha-longipinene + diphosphate


name: MET receptor dimerizes (Caenorhabditis elegans)


name: (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methyl-3-oxobutanoyl-CoA + H(+) + NADH


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Bos taurus)


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Xenopus tropicalis)


name: 26-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: 16alpha-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase]


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Drosophila melanogaster)


name: 2 3-(4-hydroxyphenyl)pyruvate + H(+) <=> (2S)-2-(4-hydoxybenzyl)-3-(4-hydroxyphenyl)-2-furonol carboxylate + H2O


name: (3S)-hydroxy-(5Z-tetradecenoyl)-CoA + NAD(+) = 3-oxo-(5Z-tetradecenoyl)-CoA + H(+) + NADH


name: Mitochondrial BTD hydrolyses BCTN (Danio rerio)


name: acarbose + ATP <=> acarbose 7(IV)-phosphate + ADP + H(+)


name: 1-phosphatidylinositol 4-kinase activator activity


name: Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure (Homo sapiens)


name: 2 H2O + ricinine <=> 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate + NH4(+)


name: L-arginine + taurocholate <=> L-arginocholate + taurine


name: Aquaporins passively transport glycerol into cells (Plasmodium falciparum)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Danio rerio)


name: SEC22B, CALR, STX4, TAP and TAPBP bind (Mus musculus)


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Mus musculus)


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: ASIC3 channel blockers bind ASIC3 trimer (Bos taurus)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Bos taurus)


name: 2-oxoglutarate + a 1,N(2)-etheno-2'-deoxyguanosine in single-stranded DNA + H2O + O2 => a 2'-deoxyguanosine in single-stranded DNA + CO2 + glyoxal + succinate


name: D-xylotetraose + O2 = D-xylotetraono-1,5-lactone + H2O2


name: an alcohol + phosphate => a phosphate monoester + H2O


name: H2O + octadecanoate ester => an aliphatic alcohol + H(+) + octadecanoate


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Homo sapiens)


name: HNP1-4 are released into phagocytic vacuoles (Homo sapiens)


name: Proteasome degrades polyubiquitinated PTEN (Drosophila melanogaster)


name: 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: 5'-deoxyadenosine + 8-methyladenosine(2503) in 23S rRNA + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine => adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine


name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Canis familiaris)


name: CSF2RA:CSF2RB binds SFTPs (Canis familiaris)


name: WDR5 binds Me2sR3-replicative histone H3 (Dictyostelium discoideum)


name: sialic acid transmembrane transporter activity


name: (9Z)-octadecenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine => 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: H(+) + menaquinol-8 + trimethylamine N-oxide = H2O + menaquinone-8 + trimethylamine


name: Phosphorylation and activation of VAV (Gallus gallus)


name: RP2:ARL3:GDP:UNC119B dissociates (Gallus gallus)


name: The p75NTR:NgR:MDGI binds RHOA-GDI (Canis familiaris)


name: Active ARF recruits coatomer (Canis familiaris)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Dictyostelium discoideum)


name: SPZ dimer bound TL dimerises at the plasma membrane (Drosophila melanogaster)


name: adenosine + H2O + 2 O2 <=> 9-riburonosyladenine + H(+) + 2 H2O2


name: 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA (Saccharomyces cerevisiae)


name: 2-dehydro-D-glucose + an aliphatic amine + H2O2 => an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2


name: inosine(out) + Na(+)(out) = inosine(in) + Na(+)(in)


name: (R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+)


name: CO2 + H2O + pentadecanal => (2R)-2-hydroperoxyhexadecanoate + H(+)


name: NADP(+) + octadecanoyl-[ACP] => (2E)-octadecenoyl-[ACP] + H(+) + NADPH


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Mus musculus)


name: isoxazolin-5-one + O-acetyl-L-serine => 3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate + H(+)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol <=> 1-octadecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: 4-aminobutanoate(in) + L-glutamate(out) = 4-aminobutanoate(out) + L-glutamate(in)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Bos taurus)


name: butanoyl-CoA + tyramine <=> CoA + H(+) + N-butanoyltyramine


name: FAAH2 hydrolyses AEA to AA and ETA (Drosophila melanogaster)


name: beta-muricholate + lithocholoyl-CoA = beta-muricholoyl-CoA + lithocholate


name: 13-cis-retinyl tetradecanoate + CoA => 13-cis-retinol + tetradecanoyl-CoA


name: Formation of active mTORC1 complex (Danio rerio)


name: (3R)-3-hydroxydodecanoyl-CoA + NAD(+) => 3-oxododecanoyl-CoA + H(+) + NADH


name: leukotriene C4 = glutathione + leukotriene A4


name: Transport of SEC22B, TAP and PLC from ER to ERGIC (Rattus norvegicus)


name: a 3-O-beta-D-glucosyl-beta-D-glucuronoside + phosphate => a beta-D-glucuronoside + alpha-D-glucose 1-phosphate


name: Profilin:G-actin binds MKL1 (Xenopus tropicalis)


name: Interaction of Tie2 and p85 of PI3K (Homo sapiens)


name: PPP1R3C binds to glycogen:GYG1:GYS1 (Bos taurus)


name: 3-oxo-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+)


name: 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA => (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine


name: (5R)-hydroxy-beta-trans-bergamotene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-exo-beta-bergamotene + O2 + reduced [NADPH--hemoprotein reductase]


name: GDP-alpha-D-mannose + H2O + 2 NAD(+) = GDP-alpha-D-mannuronate + 3 H(+) + 2 NADH


name: a 2'-deoxycytidine in single-stranded DNA + CO2 + glyoxal + succinate => 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + H2O + O2


name: hypotaurine + pyruvate <=> 2-sulfinoacetaldehyde + L-alanine


name: ADP + ATP = adenosine 3'-diphosphate,5'-diphosphate + AMP


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Sus scrofa)


name: 2-oxoglutarate + 3-sulfino-L-alanine <=> 3-sulfinopyruvate + L-glutamate


name: CBL recruits CIN85:endophilin to ubiquitinated MET (Bos taurus)


name: RHOG GAPs stimulate RHOG GTPase activity (Danio rerio)


name: AH2 + cyclooctat-9-en-7-ol + O2 <=> A + cyclooctat-9-ene-5,7-diol + H2O


name: an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] <=> 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]


name: NFkB dependent NFE2L2 expression (Homo sapiens)


name: [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase] => [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase]


name: Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: 5-hydroxymethylfurfural + O2 <=> 2,5-diformylfuran + H2O2


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Caenorhabditis elegans)


name: 2-oxosuccinamate + L-serine => 3-hydroxypyruvate + L-asparagine


name: NADSYN1 hexamer amidates NAAD to NAD+ (Dictyostelium discoideum)


name: PP2A dephosphorylates AXIN, APC and CTNNB1 in the destruction complex (Homo sapiens)


name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)


name: SYK autophosphorylates (Canis familiaris)


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Canis familiaris)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)


name: 7-methylxanthine + H(+) + NADPH + O2 <=> formaldehyde + H2O + NADP(+) + xanthine


name: Removal of fibrillar collagen N-propeptides (Homo sapiens)


name: 6-hydroxynicotinate + 2 Fe(II)-[cytochrome] + 2 H(+) => 2 Fe(III)-[cytochrome] + H2O + nicotinate


name: BIL dissociates from GSTA1, FABP1 (Canis familiaris)


name: AH2 + D-cellobiono-1,5-lactone => A + D-cellobiose


name: 3,4-dihydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 => 3,5-dibromobenzene-1,2-diol + CO2 + 4 H2O + 2 NADP(+)


name: SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Mus musculus)


name: DYRK2 phosphorylates TP53 (Mus musculus)


name: CX3 complex binds D-loop structures (Sus scrofa)


name: oxLDL:CD36 binds TLR4:TLR6 (Rattus norvegicus)


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Bos taurus)


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-pyrethrolone = CoA + pyrethrin I


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Xenopus tropicalis)


name: 6-deoxotyphasterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 6alpha-hydroxytyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate = (+)-guaia-6,9-diene + diphosphate


name: Small molecule inhibitor binds RIPK1, RIPK3 (Bos taurus)


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Mus musculus)


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) = 3-(3,4-dihydroxyphenyl)pyruvate + H(+) + NADH


name: ARSB hydrolyses C4S/C6S chains (Canis familiaris)


name: a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP => a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP-alpha-D-glucose


name: benzyl isothiocyanate <=> benzyl thiocyanate


name: 5-hydroxy-3-methyl-L-tyrosine + S-adenosyl-L-methionine <=> 5-hydroxy-3-methyl-O-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: (2E)-decenedioyl-CoA + H2O <=> (3S)-hydroxydecanedioyl-CoA


name: Formation of Cyclin B:Cdc2 complexes (Gallus gallus)


name: NUP93 recruits the Nup62 complex (Homo sapiens)


name: cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(4447) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + O2 + validamycin A <=> CO2 + H(+) + succinate + validamycin B


name: H2O + N-hexanoyl-sphinganine <=> hexanoate + sphinganine


name: ROCK1,ROCK2 are activated (Rattus norvegicus)


name: LEFTY binds the EGF-CFC coreceptor in the NODAL receptor (Homo sapiens)


name: (S)-lactate + NAD(+) = H(+) + NADH + pyruvate


name: 3,4,5-trihydroxybenzoate + UDP-alpha-D-glucose = 1-O-galloyl-beta-D-glucose + UDP


name: ERBB4 ubiquitination by WWP1/ITCH (Canis familiaris)


name: D-5-[2-(methylsulfanyl)ethyl]hydantoin + H2O <=> H(+) + N-carbamoyl-D-methionine


name: a globoside Forssman (d18:1(4E)) + H(+) + UDP => a globoside Gb4Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: (indol-3-yl)acetate + UDP-alpha-D-glucose <=> 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP


name: N,N-dihydroxy-L-aspartate <=> (2S)-2-nitrosobutanedioate + H2O


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Dictyostelium discoideum)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Mus musculus)


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Sus scrofa)


name: [protein]-peptidylproline (omega=180) <=> [protein]-peptidylproline (omega=0)


name: sucrose + UDP-alpha-D-galactose = 6(F)-alpha-D-galactosylsucrose + H(+) + UDP


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Homo sapiens)


name: H(+) + NADPH + O2 + sitosterol => 2 H2O + NADP(+) + stigmasterol


name: PP5 dephosphorylates RAF1 S338 (Sus scrofa)


name: 3-dehydro-6alpha-hydroxyteasterone + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydroteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: factor Va + factor Xa -> Va:Xa complex (prothrombinase) (Canis familiaris)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Dictyostelium discoideum)


name: H2O2 oxidises ferrohemoglobin to MetHb (Homo sapiens)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Caenorhabditis elegans)


name: geranylhydroquinone + O2 + reduced [NADPH--hemoprotein reductase] => 3''-hydroxygeranylhydroquinone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Mus musculus)


name: PIP2 hydrolysis (Caenorhabditis elegans)


name: (S)-carnitine(out) + Na(+)(out) => (S)-carnitine(in) + Na(+)(in)


name: H2O + N-terminal N(alpha)-acetyl-L-cysteinyl-L-glutamyl-[protein] = N-acetyl-L-cysteine + N-terminal L-glutamyl-[protein]


name: dodecanoate + glycerol + H(+) => 1-dodecanoylglycerol + H2O


name: H(+)(in) + melibiose(in) => H(+)(out) + melibiose(out)


name: alpha-maltohexaose + beta-D-glucose => alpha-maltopentaose + beta-maltose


name: 2-methyl-4-chlorophenol + CO2 + pyruvate + succinate => (S)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2


name: diphosphate + H(+)(in) + H2O => 2 H(+)(out) + 2 phosphate


name: 12 H(+) + 4 iron(III) oxide-hydroxide => 4 Fe(2+) + 6 H2O + O2


name: a 2'-deoxyuridine in single-stranded DNA + NH4(+) => a 2'-deoxycytidine in single-stranded DNA + H(+) + H2O


name: NAAA hydrolyses NAEs to FAs and ethanolamine (Rattus norvegicus)


name: LONP1 binds mitochondrial matrix proteins (Sus scrofa)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Dictyostelium discoideum)


name: Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)


name: p-MAPKAPK3 phosphorylates BMI1 (Sus scrofa)


name: ST3GAL2,3 transfer Neu5Ac to gangliosides (Xenopus tropicalis)


name: MSL acetylates histone H4 (Homo sapiens)


name: Collagen type I binds integrin alpha11beta1 (Caenorhabditis elegans)


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Mus musculus)


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Gallus gallus)


name: H2O + luteolin 4'-O-beta-D-glucoside <=> beta-D-glucose + luteolin


name: Caspase mediated cleavage of beta-catenin (Canis familiaris)


name: 1-hydroxy-3-methylbutan-2-one + H(+) + NADH + NH4(+) => (2S)-2-amino-3-methylbutan-1-ol + H2O + NAD(+)


name: AH2 + an aldehyde => A + a primary alcohol


name: 2,6-dihydroxypyridine + 4-(methylamino)butanoate + H(+) => 2,6-dihydroxypseudooxynicotine + H2O


name: 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + H2O = ADP-D-ribose + H(+) + L-aspartyl-[protein]


name: ATP + D-lysine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate <=> ADP + H(+) + N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine + phosphate


name: Branching and elongation of mother and daughter filaments (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(+) + UDP


name: 15-methylhexadecasphinganine + NADP(+) = 3-dehydro-15-methylhexadecasphinganine + H(+) + NADPH


name: SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Xenopus tropicalis)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Xenopus tropicalis)


name: a 2-amino-4-hydroxypteridine + H(+) + H2O = a 2,4-dihydroxypteridine + NH4(+)


name: SLC29A1 transports RBV from cytosol to extracellular region (Drosophila melanogaster)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Rattus norvegicus)


name: Degradation of ubiquitinated SKI/SKIL (Canis familiaris)


name: dihydroxyfumarate + H(+) => 2-hydroxy-3-oxopropanoate + CO2


name: CALM1:Ca2+ binds CNG channel (Gallus gallus)


name: PTK6 phosphorylates AKT1 (Caenorhabditis elegans)


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Xenopus tropicalis)


name: p-Y694-STAT5A, p-STAT5B dimerizes (Gallus gallus)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Bos taurus)


name: NADPH + 2 oxidized [cytochrome P450] = H(+) + NADP(+) + 2 reduced [cytochrome P450]


name: Cleavage of lip22 to lip10 (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] = (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O => (9Z)-octadecenoate + H(+) + sn-glycero-3-phospho-L-serine


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Xenopus tropicalis)


name: A + all-trans-zeta-carotene = AH2 + all-trans-neurosporene


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Dictyostelium discoideum)


name: D-mannitol + 2 Fe(III)-[cytochrome c] => D-fructose + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: citrate(in) + phosphoenolpyruvate(out) => citrate(out) + phosphoenolpyruvate(in)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Homo sapiens)


name: a 2'-deoxyribonucleoside + a ribonucleoside 5'-phosphate => a 2'-deoxyribonucleoside 5'-phosphate + a ribonucleoside


name: citrate(in) + H(+)(in) <=> citrate(out) + H(+)(out)


name: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine => 3',4',5-trihydroxy-3,7-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: GNE phosphorylates ManNAc to ManNAc-6-P (Mus musculus)


name: 2-oxoglutarate + L-asparagine + O2 <=> (2S,3S)-3-hydroxyasparagine + CO2 + succinate


name: CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D (Homo sapiens)


name: RBP4:atROL binds TTR (Caenorhabditis elegans)


name: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 => H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone


name: corticotrophin-releasing factor receptor activity


name: Interaction of DAP12 and KIR2DS1 (Homo sapiens)


name: (2-aminoethyl)phosphonate + CTP = CMP-(2-aminoethyl)phosphonate + diphosphate


name: Interaction of GPVI and FceRI gamma (Sus scrofa)


name: (22R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (22R,7alpha)-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Canis familiaris)


name: 3-methyl-(2E)-glutaconyl-CoA + N(6)-biotinyl-L-lysyl-[protein] => 3-methyl-(2E)-butenoyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein]


name: SUMOylation of PML with SUMO3 (Mus musculus)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Bos taurus)


name: (2E,6E)-farnesyl diphosphate => (+)-germacrene D + diphosphate


name: H2O + sn-glycero-3-phospho-1D-myo-inositol => H(+) + myo-inositol + sn-glycerol 3-phosphate


name: 2xTPK1:Mg2+ phosphorylates THMN (Xenopus tropicalis)


name: CoA + N-acetyl-4-O-acetylneuraminate => acetyl-CoA + N-acetylneuraminate


name: a neolactoside IV(2)-alpha-Fuc-nLc4Cer + GDP + H(+) => a neolactoside nLc4Cer + GDP-beta-L-fucose


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Danio rerio)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Gallus gallus)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Drosophila melanogaster)


name: Calcineurin binds NFATC1,2,3 (Homo sapiens)


name: Cleavage of DFF45 (224) by caspase-3 (Drosophila melanogaster)


name: RHOD binds effectors at the Golgi membrane (Mus musculus)


name: H(+) + heptan-2-one + NADPH + O2 <=> H2O + NADP(+) + pentyl acetate


name: De novo formation of eIF2:GTP (Gallus gallus)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + methanol


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Saccharomyces cerevisiae)


name: fumarate + L-aspartate <=> iminosuccinate + succinate


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O <=> 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Canis familiaris)


name: NAD(+) + propane-1,3-diol => 3-hydroxypropanal + H(+) + NADH


name: 5'-deoxy-5'-fluoroadenosine + L-methionine => fluoride + S-adenosyl-L-methionine


name: Follistatin (FST) binds Activin (Rattus norvegicus)


name: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+)


name: NF1 is degraded by the proteasome (Dictyostelium discoideum)


name: dihydrochelirubine + NAD(+) => chelirubine + NADH


name: MTA is cleaved and phosphorylated (Saccharomyces cerevisiae)


name: Plasmin proteolyzes IGF:IGFBP-3:ALS (Rattus norvegicus)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O => 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Caenorhabditis elegans)


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Danio rerio)


name: KIAA0101 double monoubiquitination (Gallus gallus)


name: an aromatic aldehyde + H2O + NAD(+) => an aromatic carboxylate + 2 H(+) + NADH


name: MAPK8 phosphorylation (Canis familiaris)


name: ATP + CoA + isophthalate => AMP + diphosphate + isophthalyl-CoA


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Sus scrofa)


name: DHFR gene expression is stimulated by E2F1 (Homo sapiens)


name: Phosphorylation of pPTK2 by SRC (Sus scrofa)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Dictyostelium discoideum)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADP(+) = 7,12-dioxo-lithocholate + H(+) + NADPH


name: FUK phosphorylates beta-Fuc to Fuc1P (Caenorhabditis elegans)


name: RAB1:GTP recruits GBF1 to the ERGIC (Saccharomyces cerevisiae)


name: H(+)(out) + L-alanyl-D-glutamate(out) = H(+)(in) + L-alanyl-D-glutamate(in)


name: NPC2 binds CHOL (Caenorhabditis elegans)


name: 3-sulfino-L-alanine + H2O => H(+) + L-alanine + sulfite


name: 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+) => 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O2


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation  (Homo sapiens)


name: H(+) + tRNA(Ala) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alanine => L-alanyl-tRNA(Ala) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine


name: FBXO32 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) (Homo sapiens)


name: H(+) + NADPH + O2 + progesterone => H2O + NADP(+) + testosterone acetate


name: Conversion of C2 into C2a and C2b (Homo sapiens)


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Homo sapiens)


name: Cortisol translocates from the mitochondrial matrix to the cytosol (Homo sapiens)


name: YOD1 binds VCP (Dictyostelium discoideum)


name: H2O + N(epsilon)-(5'-guanylyl)-N(alpha)-acetyl-L-lysine methyl ester <=> GMP + N(alpha)-acetyl-L-lysine methyl ester


name: Dephosphorylation of inactive SRC by PTPB1 (Rattus norvegicus)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Sus scrofa)


name: 2-acyl LPG is acylated to PG by LPGAT (Plasmodium falciparum)


name: (+)-malbrancheamide B + chloride + FAD + 2 H(+) => (+)-malbrancheamide + FADH2


name: beta-cryptoxanthin + O2 = (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal


name: cAMP degradation by Phosphodiesterases (Mus musculus)


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + L-lysyl(9)-[histone H3] + 2 succinate


name: 4-aminobutanal + H2O + NAD(+) <=> 4-aminobutanoate + 2 H(+) + NADH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O


name: SUMOylation of DDX5 with SUMO1 (Plasmodium falciparum)


name: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Homo sapiens)


name: 3-oxo-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + CO2 + CoA => (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + malonyl-CoA


name: dihydroorotate dehydrogenase (fumarate) activity


name: SMURF2 monoubiquitinates SMAD3 (Bos taurus)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Danio rerio)


name: ATG10:ATG12 binds ATG5 (Canis familiaris)


name: 7,8-dihydroneopterin <=> 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde


name: loading of Serotonin in synaptic vesicles (Bos taurus)


name: neryl diphosphate => beta-phellandrene + diphosphate


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Homo sapiens)


name: 1-methyl-3-phenylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => fenuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 => 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O


name: 2-oxopent-4-enoate + benzoate + H(+) => 2,6-dioxo-6-phenylhexa-3-enoate + H2O


name: BP230 interacts with keretin K5/K14 (Homo sapiens)


name: 1-hexadecanoylglycerone 3-phosphate + hexadecan-1-ol = 1-O-hexadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: Phosphorylation of PKC-theta (Rattus norvegicus)


name: (9Z)-tetradecenoate(out) + ATP(in) + CoA(in) + H(+)(out) <=> (9Z)-tetradecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: 2 Fe(2+) + 4 H2O + O2 => 6 H(+) + H2O2 + 2 iron(III) oxide-hydroxide


name: MMAB adenosylates cob(I)alamin (Homo sapiens)


name: H(+) + H2O + quinolinate => 3-hydroxyanthranilate + O2


name: N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: OSCAR binds collagen and SP-D (Sus scrofa)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Homo sapiens)


name: MPI isomerises Fru6P to Man6P (Homo sapiens)


name: a 2'-deoxyribonucleoside 5'-phosphate + ATP <=> a 2'-deoxyribonucleoside 5'-diphosphate + ADP


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Saccharomyces cerevisiae)


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Gallus gallus)


name: uridine transmembrane transporter activity


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphate <=> 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate


name: Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Bos taurus)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Homo sapiens)


name: APP(672-713),APP(672-711) translocate from endosome lumen to extracellular region (Homo sapiens)


name: a dicarboxylate(in) + sulfate(out) => a dicarboxylate(out) + sulfate(in)


name: H2O + L-threonyl-tRNA(Val) => L-threonine + tRNA(Val)


name: Phosphorylated MAPKs phosphorylate ATF-2 (Rattus norvegicus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N(omega)-hydroxy-N(delta)-methyl-L-arginine => 2 Fe(III)-[cytochrome b5] + H2O + N(delta)-methyl-L-arginine


name: H2O + paraoxon => 4-nitrophenol + diethylphosphate + 2 H(+)


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Danio rerio)


name: CO2 + diphosphate + thiamine phosphate => 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+)


name: S-adenosyl-L-methionine + taxifolin <=> H(+) + S-adenosyl-L-homocysteine + taxifolin 4'-methyl ether


name: prostaglandin J2 <=> Delta(12)-prostaglandin J2


name: AP2 binds chlorpromazine (Drosophila melanogaster)


name: ethylnitronate + FMNH2 + O2 => acetaldehyde + FMN + 2 H(+) + H2O + nitrite


name: cyclohexane-1-carbonyl-CoA + NADP(+) <=> cyclohex-1-ene-1-carbonyl-CoA + H(+) + NADPH


name: "Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors"


name: TGFBR3 phosphorylation by TGFBR2 complex (Homo sapiens)


name: a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1b + CMP + H(+)


name: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Homo sapiens)


name: (10aS)-10,10a-dihydrophenazine-1-carboxylate => 5,10-dihydrophenazine 1-carboxylate


name: SORD tetramer oxidizes xylitol to D-xylulose (Mus musculus)


name: Trafficking of GluR2-containing AMPA receptors to synapse (Rattus norvegicus)


name: 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Xenopus tropicalis)


name: Conjugation of SUMO1 to UBA2:SAE1 (Caenorhabditis elegans)


name: AH2 + GTP + S-adenosyl-L-methionine = 3'-deoxy-3',4'-didehydro-GTP + 5'-deoxyadenosine + A + H(+) + H2O + L-methionine


name: CREB3L3 translocates from the cytosol to the nucleus (Canis familiaris)


name: 5-methylcytidine(38) in tRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(38) in tRNA + S-adenosyl-L-methionine


name: RNF34 or RFFL ubiquitinates phosphorylated TP53 (Bos taurus)


name: Loading of dopamine into synaptic veiscles (Bos taurus)


name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Homo sapiens)


name: ACER3 hydrolyzes phytoceramide (Homo sapiens)


name: 2,5-diformylfuran + H2O2 => 5-hydroxymethylfurfural + O2


name: H(+) + L-glutamate + NADH => (S)-1-pyrroline-5-carboxylate + 2 H2O + NAD(+)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: monoglucosyl-enterobactin + UDP => enterobactin + UDP-alpha-D-glucose


name: Grb7 binds to the active PDGF receptor (Canis familiaris)


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Bos taurus)


name: Interaction of DAP12 and TREM2 (Sus scrofa)


name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] (Sus scrofa)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Xenopus tropicalis)


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Danio rerio)


name: Butyrylcholinesterase hydrolyzes acyl Ghrelin (Homo sapiens)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Bos taurus)


name: STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Gallus gallus)


name: Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Bos taurus)


name: N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate <=> H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Danio rerio)


name: CD22 binds B-cell receptor (Mus musculus)


name: 7-methylmellein + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 7-carboxymellein + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: succinate(out) + urate(in) => succinate(in) + urate(out)


name: glucosinolate transmembrane transporter activity


name: 6-sulfo-D-glucono-1,5-lactone + H(+) + NADPH => D-glucose 6-sulfate + NADP(+)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + succinate


name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 (Bos taurus)


name: Activation of Rap1 by membrane-associated GEFs (Mus musculus)


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphoserine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine


name: ROS,RNS oxidize ACO2:4Fe-4S (Schizosaccharomyces pombe)


name: Activated protein C binds Protein S (Rattus norvegicus)


name: NRXNs bind CASK:Protein 4.1 (Drosophila melanogaster)


name: VAV2 is a GEF for Rho/Rac family kinases (Mus musculus)


name: holo-FDPS dimer binds NBPs (Plasmodium falciparum)


name: GDP + H(+) + oxidized coenzyme F420-2 + phosphate => GTP + L-glutamate + oxidized coenzyme F420-1


name: 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Sus scrofa)


name: hydroxymethylphosphonate + O2 = formate + 2 H(+) + phosphate


name: H(+)(out) + L-phenylalanyl-L-phenylalanine(out) => H(+)(in) + L-phenylalanyl-L-phenylalanine(in)


name: G protein-coupled cytokinin receptor activity


name: (S)-2,3-diaminopropanoate + 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + ATP = 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + AMP + diphosphate


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Rattus norvegicus)


name: p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Sus scrofa)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Mus musculus)


name: 7(1)-hydroxychlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => chlorophyllide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO2 + NADH


name: p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) (Homo sapiens)


name: ATP + docosanoate + H(+) <=> diphosphate + docosanoyl-AMP


name: ATP + S-disulfanyl-L-cysteine + tRNA(Cys) => (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate


name: AR binds AR antagonists (Drosophila melanogaster)


name: 4-hydroxybenzaldehyde + H2O + NAD(+) <=> 4-hydroxybenzoate + 2 H(+) + NADH


name: alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-3,6-dideoxy-alpha-D-mannose = alpha-D-Tyv-(1->3)-alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol => [thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite


name: NTP Binds Active Site of RNA Polymerase II (Sus scrofa)


name: (S)-2,3-dihydrodipicolinate + NADP(+) <=> dipicolinate + H(+) + NADPH


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + CTP + H(+) = CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + diphosphate


name: Apical transport of Cipro to extracellular space (Homo sapiens)


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Rattus norvegicus)


name: p-DAPP1 (p-BAM32) binds PLCG2 (Plasmodium falciparum)


name: TPMT transfers CH3 from AdoMet to 6MP (Sus scrofa)


name: (2R,3R)-dihydromyricetin + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => (2R,3R)-dihydrokaempferol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: Basigin binds Matrix metalloproteinase-1 (Caenorhabditis elegans)


name: ABCA4 mediates atRAL transport (Drosophila melanogaster)


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Canis familiaris)


name: B3GAT dimers transfer GlcA to tetrasaccharide linker (Xenopus tropicalis)


name: a ganglioside GM1 + H2O = a ganglioside GA1 + N-acetylneuraminate


name: 5-epi-alpha-selinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: AKT-phosphorylated FOXO3 translocates to cytosol (Drosophila melanogaster)


name: GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)


name: PP2A dephosphorylates phosphorylated CLK (Drosophila melanogaster)


name: SHC1 in the RET complex is phosphorylated (Mus musculus)


name: Caspase mediated cleavage of beta-catenin (Xenopus tropicalis)


name: H(+) + L-methionine <=> 3-(methylsulfanyl)propanamine + CO2


name: CYCS:APAF1 binds procaspase-9 (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+) => a CDP-1,2-diacyl-sn-glycerol + myo-inositol


name: [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity


name: 2 glutathione + L,L-homocystine = glutathione disulfide + 2 L-homocysteine


name: ST metabolites diffuse out of ER lumen (Homo sapiens)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Bos taurus)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Drosophila melanogaster)


name: L-idonate + NADP(+) = 2-dehydro-L-idonate + H(+) + NADPH


name: Receptor ACKR2 binds most inflammatory CC chemokines (Homo sapiens)


name: Ca2+ influx into the post-synaptic cell (Canis familiaris)


name: (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H(+) + NADPH = (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + NADP(+)


name: Keratin type I binds keratin type II (Danio rerio)


name: ethanol + o-quinone methide = hydroxyclavatol ethyl ether


name: SLC5A6 transports vitamins from extracellular region to cytosol (Rattus norvegicus)


name: a (3R)-3-hydroxyacyl-CoA => a (3S)-3-hydroxyacyl-CoA


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Danio rerio)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Canis familiaris)


name: alpha-L-arabinopyanose + NADP(+) = H(+) + L-arabinono-1,4-lactone + NADPH


name: HSPD1 gene expression is repressed by the complex of NPM1 and TFAP2A homodimer (Homo sapiens)


name: scopoletin + UDP-alpha-D-glucose => H(+) + scopolin + UDP


name: H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(966) in 16S rRNA + S-adenosyl-L-methionine


name: (9Z,12Z)-octadecadienoate + 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O


name: 3'-phosphoadenylyl sulfate + estrone <=> adenosine 3',5'-bisphosphate + estrone 3-sulfate + H(+)


name: Trimerization of HSF1 in the nucleus (Canis familiaris)


name: H(+)(in) + L-threonine(in) = H(+)(out) + L-threonine(out)


name: Aquaporin-7 passively transports glycerol out of cell (Saccharomyces cerevisiae)


name: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2


name: choline(out) + n H(+)(in) = choline(in) + n H(+)(out)


name: NSF and SNAPs bind cis-SNARE complex (Homo sapiens)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Homo sapiens)


name: Aquaporins passively transport glycerol into cells (Gallus gallus)


name: ATP4A:ATP4B exchanges K+ for H+ (Rattus norvegicus)


name: ADP + H(+) + methionine(in) + phosphate => ATP + H2O + methionine(out)


name: PGLYRP2 binds bacterial peptidoglycan (Mus musculus)


name: BTN2A2 binds T cell surface (Rattus norvegicus)


name: H(+) + UDP-alpha-D-galacturonate = CO2 + UDP-beta-L-arabinopyranose


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Drosophila melanogaster)


name: 7-methylxanthine + formaldehyde + H2O + NAD(+) => H(+) + NADH + O2 + theobromine


name: AKR1C3 reduces atRAL to atROL (Rattus norvegicus)


name: histone H4K20 methyltransferase activity


name: SFTPB binds itself (Drosophila melanogaster)


name: Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Gallus gallus)


name: AH2 + O2 + octadecanoyl-CoA => (9Z)-octadecenoyl-CoA + A + 2 H2O


name: PG and CDP-DAG are converted to CL by CRLS1 (Danio rerio)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => ent-8alpha-hydroxylabd-13-en-15-yl diphosphate


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Drosophila melanogaster)


name: a 1,2-diacyl-3-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine => a 1,2-diacylglycerol + an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine


name: SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Drosophila melanogaster)


name: 3alpha-hydroxyetiocholan-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)


name: WNT5A binds FZD and ROR receptors (Caenorhabditis elegans)


name: MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Drosophila melanogaster)


name: PIAS1 SUMOylates SATB2 with SUMO3 (Gallus gallus)


name: H2O + substance P = L-Leu-L-Met-NH2 + substance P(1-9)


name: LIPT2 transfers octanoyl group to GCSH (Canis familiaris)


name: a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate => a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O


name: alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose <=> [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + H(+) + UDP


name: H2O + N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] => (S)-4,5-dihydroxy-2-oxopentanal + L-lysyl-[protein] + phosphate


name: Expression of PAX2 in intermediate mesoderm (Homo sapiens)


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Dictyostelium discoideum)


name: acetyl-CoA + 3 AH2 + 18 H(+) + 10 malonyl-CoA + 8 NADPH = 3 A + 10 CO2 + 11 CoA + cordypyrone A + 8 H2O + 8 NADP(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + hexadecanoate + hexadecanoyl-glycero-3-phospho-(1D-myo-inositol) => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: AMP(in) + FMN(out) => AMP(out) + FMN(in)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Saccharomyces cerevisiae)


name: D-maltoheptaose + O2 <=> D-maltoheptaono-1,5-lactone + H2O2


name: acetyl-CoA + beta-D-glucose => 6-O-acetyl-beta-D-glucose + CoA


name: DNA polymerase alpha:primase binds at the origin (Gallus gallus)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Xenopus tropicalis)


name: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine => [sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine


name: glycyl-L-methionine + H2O <=> glycine + L-methionine


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Rattus norvegicus)


name: AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Homo sapiens)


name: a (2S)-2-hydroxycarboxylate + NAD(+) = a 2-oxocarboxylate + H(+) + NADH


name: GTP-binding activates eEF2 (Xenopus tropicalis)


name: Interaction of Csk with PAG (Gallus gallus)


name: UVSSA:USP7 deubiquitinates ERCC6 (Homo sapiens)


name: FAD attaches to SDHA (Xenopus tropicalis)


name: succinate transmembrane transporter activity


name: Exocytosis of tertiary granule lumen proteins (Saccharomyces cerevisiae)


name: Gamma-secretase cleaves YBX1:NOTCH3 (Homo sapiens)


name: FMO2:FAD:Mg2+ S-oxidises MTZ (Sus scrofa)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl-[protein] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl-[protein] + succinate


name: CTLH E3 ligase ubiquitinates LDHA (Canis familiaris)


name: AH2 + O2 + progesterone = 11alpha-hydroxyprogesterone + A + H2O


name: 7-oxocholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-3beta,26-dihydroxycholest-5-en-7-one + H2O + 2 oxidized [adrenodoxin]


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Mus musculus)


name: a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] <=> 7-oxoheptanoyl-[ACP] + a fatty aldehyde + H(+) + 2 H2O + oxidized [flavodoxin]


name: a 2-oxocarboxylate + L-ornithine <=> an L-alpha-amino acid + L-glutamate 5-semialdehyde


name: (11Z)-eicosenoyl-CoA + NADP(+) => (2E,11Z)-eicosadienoyl-CoA + H(+) + NADPH


name: 2,4-dibromophenol + CO2 + 4 H2O + 2 NADP(+) => 4-hydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2


name: Loading of antigenic peptides (Mus musculus)


name: a short-chain fatty acyl-CoA + AMP + diphosphate => a short-chain fatty acid + ATP + CoA


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Xenopus tropicalis)


name: Active FLT3 binds to CSK (Canis familiaris)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Rattus norvegicus)


name: 1,6-dihydro-beta-NAD + H(+) + O2 = H2O2 + NAD(+)


name: 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Sus scrofa)


name: a 3-oxosteroid + CO2 + NADPH => a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+)


name: Agmatine + H2O <=> putrescine + urea (Bos taurus)


name: menaquinone-7 + succinate = fumarate + menaquinol-7


name: TFAM binds to mitochondrial promoters (Caenorhabditis elegans)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Rattus norvegicus)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2 => 2-dehydro-D-glucose + glycine + H2O2


name: Gamma-secretase cleaves YBX1:NOTCH3 (Rattus norvegicus)


name: 25-hydroxycholesterol + H2O + NADP(+) => cholesterol + H(+) + NADPH + O2


name: H2O + N(1)-acetylspermidine + O2 = 4-acetamidobutanal + H2O2 + propane-1,3-diamine


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Homo sapiens)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Drosophila melanogaster)


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Dictyostelium discoideum)


name: a cholesterol ester(in) = a cholesterol ester(out)


name: an anthocyanidin 3-O-beta-D-sambubioside + UDP-alpha-D-glucose <=> an anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + H(+) + UDP


name: a 2-demethylmenaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine <=> 5'-deoxyadenosine + a 2-demethyl-8-methylmenaquinone + 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L-homocysteine


name: 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: Ub,pS335,S338,T NFE2L2 is degraded (Canis familiaris)


name: 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase]


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Gallus gallus)


name: (3R)-3-isocyanylbutanoyl-AMP + diphosphate => (3R)-3-isocyanylbutanoate + ATP + H(+)


name: Thrombin-activated PARs:G12/13 (active) dissociate (Gallus gallus)


name: Phosphorylated PXN recruits the CRK complex (Sus scrofa)


name: sphinganine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoylsphinganine


name: Collagen type II binds integrin alpha10beta1 (Canis familiaris)


name: NADP(+) + UDP-beta-L-rhamnose => H(+) + NADPH + UDP-4-dehydro-beta-L-rhamnose


name: 4-hydroxybenzoate + CoA + H(+) => 4-hydroxybenzoyl-CoA + H2O


name: NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP (Sus scrofa)


name: PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Mus musculus)


name: a ribonucleotidyl-ribonucleotide-RNA = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA


name: geraniol kinase activity (ATP-dependent) activity


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Homo sapiens)


name: (11Z)-eicosenoate + glycerol + H(+) => 1-(11Z-eicosenoyl)-glycerol + H2O


name: HIPK2 phosphorylates RUNX1 and EP300 (Homo sapiens)


name: Phosphorylation of SMO by CKIalpha (Drosophila melanogaster)


name: a 3'-end 2'-deoxyribonucleotide-DNA + phosphate => a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H2O


name: GRB2-1:SOS1 binds p-Y427-SHC1 (Mus musculus)


name: PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Mus musculus)


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) <=> 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)


name: eicosanoyl-CoA + sphing-4-enine => CoA + H(+) + N-eicosanoyl-sphing-4-enine


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Canis familiaris)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Xenopus tropicalis)


name: Dissociation of CaM and CAMK2 autophosphorylation (Drosophila melanogaster)


name: (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + CoA => (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + octanoyl-CoA


name: a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine => a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine


name: 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Homo sapiens)


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Bos taurus)


name: 1-propanol + butanoyl-CoA => CoA + propyl butanoate


name: an L-alpha-amino acid + ATP + L-arginine => ADP + H(+) + L-arginyl-L-alpha-amino acid + phosphate


name: 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + UDP-alpha-D-glucose


name: (E)-cinnamyl acetate + CoA => (E)-cinnamyl alcohol + acetyl-CoA


name: MEOS oxidizes ethanol to acetaldehyde (Xenopus tropicalis)


name: (E)-feruloylacetyl-CoA + CO2 + CoA => (E)-feruloyl-CoA + H(+) + malonyl-CoA


name: 5beta-scymnol sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 5beta-scymnol


name: Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Mus musculus)


name: H(+)(out) + novobiocin(in) => H(+)(in) + novobiocin(out)


name: H2O + L,L-cystathionine => 2-oxobutanoate + L-cysteine + NH4(+)


name: Lsm1-7 Complex binds deadenylated mRNA (Danio rerio)


name: Activation of Cdc42 by pVav1 (Xenopus tropicalis)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphoglycerol + H2O => (9Z)-octadecenoate + a 2-acyl-sn-glycero-3-phosphoglycerol + H(+)


name: Phosphorylation of nephrin by FYN (Danio rerio)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Caenorhabditis elegans)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Gallus gallus)


name: FADH2-C4alpha-hydroperoxide + NADPH + rifampicin => FADH2 + H(+) + H2O + NADP(+) + rifampicin hemiaminal


name: Release of novel PDGFs as latent factors (Gallus gallus)


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Sus scrofa)


name: 4-hydroxybenzoate + H(+) <=> CO2 + phenol


name: me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1 RNA (Homo sapiens)


name: GLYCTK phosphorylates DGA to 3PDGA (Drosophila melanogaster)


name: a 3-carboxymethyl-3-hydroxyacyl-[ACP] => a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H2O


name: lipoxin A4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-lipoxin A4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose => an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc derivative + GDP + H(+)


name: PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: TRPM4,5 transport extracellular Na+ to cytosol (Bos taurus)


name: Formation of CDK4/6:CCND complexes (Mus musculus)


name: AP-1 transcription factor binds IGFBP7 promoter (Homo sapiens)


name: Phosphorylated PXN recruits the CRK complex (Gallus gallus)


name: n H(+)(out) + L-histidine(out) = n H(+)(in) + L-histidine(in)


name: Autocatalytic activation of proMMP2 (Homo sapiens)


name: butanoate(in) + dehydroepiandrosterone 3-sulfate(out) => butanoate(out) + dehydroepiandrosterone 3-sulfate(in)


name: GLA hydrolyzes PSAP(195-273):Gb3Cer:PE (Sus scrofa)


name: Expression of Erythropoietin (EPO) (Homo sapiens)


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Mus musculus)


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate => [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Xenopus tropicalis)


name: [LarE protein]-L-cysteine + ATP + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide <=> [LarE protein]-dehydroalanine + AMP + diphosphate + H(+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Homo sapiens)


name: A1 and A3 receptors bind adenosine (Gallus gallus)


name: ADP-L-glycero-beta-D-manno-heptose + L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) = ADP + H(+) + L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Xenopus tropicalis)


name: 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: a ganglioside GA1 (d18:1(4E)) + GDP-beta-L-fucose => a ganglioside Fuc-GA1 (d18:1(4E)) + GDP + H(+)


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Schizosaccharomyces pombe)


name: dodecanamide + H2O = dodecanoate + NH4(+)


name: folate:monoatomic anion antiporter activity


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Schizosaccharomyces pombe)


name: PTGS2 dimer binds PTGS2 inhibitors (Sus scrofa)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Dictyostelium discoideum)


name: Superoxide reduces cytochrome c (Plasmodium falciparum)


name: UCP1 imports a proton (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> cycloaraneosene + diphosphate


name: protein phosphorylated amino acid binding


name: ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate + umbelliferone => 8-geranylumbelliferone + diphosphate


name: 2,3-dihydroxybenzoate + O2 <=> 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)


name: (R)-carnitine + 2-methylbutanoyl-CoA = CoA + O-2-methylbutanoyl-(R)-carnitine


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Mus musculus)


name: 3 A + biliverdin IXdelta + CO + Fe(2+) + 3 H2O => 3 AH2 + 3 H(+) + heme b + 3 O2


name: D-gluconate + FAD + H(+) <=> 2-dehydro-D-gluconate + FADH2


name: Activated JNKs phosphorylate c-JUN (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate = Delta(6)-protoilludene + diphosphate


name: Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Bos taurus)


name: (S)-3'-hydroxy-N-methylcoclaurine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-N-methylcoclaurine + O2 + reduced [NADPH--hemoprotein reductase]


name: 5 H(+) + L-pipecolate + malonyl-CoA + 3 NADPH => (1R,8aS)-octahydroindolizin-1-ol + CO2 + CoA + 2 H2O + 3 NADP(+)


name: STARD7 transports Q10 to plasma membrane (Homo sapiens)


name: The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Mus musculus)


name: decanoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => dec-9-enoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ARMS is phosphorylated by active TrkA receptor (Gallus gallus)


name: DHF is reduced to tetrahydrofolate (THF) (Dictyostelium discoideum)


name: chlorate(in) + 2 Na(+)(in) => chlorate(out) + 2 Na(+)(out)


name: oligosaccharide transporting porin activity


name: AKT-phosphorylated FOXO3 translocates to cytosol (Bos taurus)


name: anthocyanin A11 + CoA => anthocyanin A10 + malonyl-CoA


name: ATP + butanoate => ADP + butanoyl phosphate


name: KIR2DL1 interacting with HLA-C group 2 (Cw3) (Rattus norvegicus)


name: [(3R)-hydroxybutanoate](n) + H2O => (3R)-hydroxybutanoate tetramer + [(3R)-hydroxybutanoate](n-4) + H(+)


name: Receptor CCR6 binds CCL20 ligand (Homo sapiens)


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Mus musculus)


name: cadmium ion transmembrane transporter activity


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Schizosaccharomyces pombe)


name: Association of procollagen type X (Sus scrofa)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Homo sapiens)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA (Canis familiaris)


name: all-trans-zeaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] => all-trans-beta-carotene + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: high-affinity secondary active nitrite transmembrane transporter activity


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Mus musculus)


name: histone H2AK119 ubiquitin ligase activity


name: Relocalization of nuclearly localized Cyclin D1 to the cytoplasm (Danio rerio)


name: D-mannose(in) + Na(+)(in) => D-mannose(out) + Na(+)(out)


name: dec-9-enoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = dec-9-ynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: CoA + H(+) + N-caffeoylputrescine => (E)-caffeoyl-CoA + putrescine


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + trichobrasilenol


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine => 2 2-hexadecanoyl-sn-glycero-3-phosphocholine


name: Interaction of SOS with GRB2 bound to FADK1 (Canis familiaris)


name: Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. (Xenopus tropicalis)


name: Phosphorylation (Ser5) of RNA pol II CTD (Canis familiaris)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Bos taurus)


name: CoA + O-pentanoyl-L-seryl-[protein] => L-seryl-[protein] + pentanoyl-CoA


name: PEX3:PEX19:class I PMP dissociates (Dictyostelium discoideum)


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Mus musculus)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Drosophila melanogaster)


name: NEXT3 is cleaved to produce NICD3 (Rattus norvegicus)


name: kaempferol + UDP-alpha-D-xylose = H(+) + kaempferol 3-O-beta-D-xyloside + UDP


name: P2Y14 receptor can bind to UDP-glucose (Mus musculus)


name: methylglyoxal reductase (NADPH) activity


name: Type B histone acetlytransferase complex acetylates histone H4 (Sus scrofa)


name: methanesulfonate + NADH + O2 <=> formaldehyde + H2O + NAD(+) + sulfite


name: AICAR + 10-Formyl-THF => FAICAR + THF (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate => 1-(9Z-octadecenoyl)-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: gamma-lactone-2-keto[5.5.5.5]fenestrane + H(+) + NADPH + O2 = H2O + NADP(+) + penifulvin A


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Bos taurus)


name: PGH2 is isomerised to PGE2 by PTGES (Mus musculus)


name: 9H-fluoren-9-ol + NADP(+) = 9H-fluoren-9-one + H(+) + NADPH


name: GSS:Mg2+ dimer synthesizes GSH (Drosophila melanogaster)


name: N-geranyl-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N-(8'-hydroxygeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase]


name: (24S,25R)-24,26-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine <=> (6S)-5,6,7,8-tetrahydrofolate + L-methionine


name: Nitrogen dioxide is reduced to NO by F420 (Homo sapiens)


name: caffeine + H(+) + NADH + O2 => formaldehyde + H2O + NAD(+) + theobromine


name: glycine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoylglycine


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Drosophila melanogaster)


name: AcK-NFE2L2 and MAFK bind NQO1 gene (Homo sapiens)


name: 2 Fe(III)-[cytochrome c] + H2O + thiocyanate <=> cyanate + 2 Fe(II)-[cytochrome c] + 2 H(+) + sulfur


name: isoliquiritigenin + S-adenosyl-L-methionine => 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine


name: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O => (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H(+)


name: AMP + diphosphate + nicotinyl-CoA => ATP + CoA + nicotinate


name: 1-deoxy-D-xylulose + ATP => 1-deoxy-D-xylulose 5-phosphate + ADP + H(+)


name: chenodeoxycholate + NAD(+) => 7-oxolithocholate + H(+) + NADH


name: (R)-1-aminopropan-2-yl phosphate + adenosylcob(III)yrate + ATP => adenosylcob(III)inamide phosphate + ADP + H(+) + phosphate


name: Receptor-mediated uptake of HA (Sus scrofa)


name: 2,3-diacyl-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP => H2O + UDP-2,3-diacyl-alpha-D-glucosamine


name: TORC2 (mTOR) phosphorylates AKT at S473 (Homo sapiens)


name: Syndecan-1 binds Integrin alphaVbeta3 (Homo sapiens)


name: Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL (Homo sapiens)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Homo sapiens)


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Mus musculus)


name: p-Y348-SYK dissociates (Canis familiaris)


name: ATP + thiamine phosphate => ADP + thiamine diphosphate


name: H(+) + methanol + N-(1H-1,3-benzodiazol-2-yl)carbamate => carbendazim + H2O


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: NADP(+) + sphinganine <=> 3-oxosphinganine + H(+) + NADPH


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose => beta-D-Glc-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + succinate


name: 1-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + glycerol + H(+)


name: [phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O <=> [phosphatase 2A protein]-C-terminal L-leucine + H(+) + methanol


name: a ganglioside Fuc-GM1 + H2O = alpha-Fuc-(1->2)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-Glc + an N-acyl-sphingoid base


name: NT5E:Zn2+ hydrolyses NAD+ (Xenopus tropicalis)


name: SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Sus scrofa)


name: BDNF gene expression is stimulated by NPAS4:ARNT2 (Homo sapiens)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: ATP + H(+) + pyridinium-3,5-dicarboxylate mononucleotide = 5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate + diphosphate


name: Latent TGF-beta-1 is cleaved by FURIN (Mus musculus)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Homo sapiens)


name: Activation of proMMP7 by MMP3 (Homo sapiens)


name: phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate (Homo sapiens)


name: NOTCH4 mRNA translation controlled by miRNAs (Homo sapiens)


name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (Rattus norvegicus)


name: cyclohexane-1-carbonyl-CoA + NADP(+) => cyclohex-1-ene-1-carbonyl-CoA + H(+) + NADPH


name: dihydro-ML-236C-[compactin nonaketide synthase] + H2O = dihydro-ML-236C carboxylate + H(+) + holo-[compactin nonaketide synthase]


name: UDP-alpha-D-glucuronate(out) + UMP(in) => UDP-alpha-D-glucuronate(in) + UMP(out)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Saccharomyces cerevisiae)


name: (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA + H(+) + NADPH = (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + NADP(+)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> (-)-somaliensene B + diphosphate


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)


name: Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha  (Gallus gallus)


name: (6S)-5,6,7,8-tetrahydrofolate + N,N-dimethylglycine + O2 <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O2 + sarcosine


name: RNASEs bind bacterial LPS, PGN (Bos taurus)


name: MITF-M dimer binds the PMEL gene (Homo sapiens)


name: AS3MT transfers CH3 from AdoMet to arsenite(3-) (Sus scrofa)


name: Activation of RAC1 by the PXN:CRK complex (Rattus norvegicus)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Drosophila melanogaster)


name: DLST transfers glutaryl to CoA (Xenopus tropicalis)


name: C3b binds to cell surface (Homo sapiens)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Dictyostelium discoideum)


name: acetoacetyl-CoA + H(+) + NADPH => (3S)-3-hydroxybutanoyl-CoA + NADP(+)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Canis familiaris)


name: Initial activation of proMMP2 by MMP14 (Homo sapiens)


name: ULK complex translocates to the ER (Sus scrofa)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Sus scrofa)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Mus musculus)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Rattus norvegicus)


name: (11R)-carlactonoate + S-adenosyl-L-methionine => (11R)-methyl carlactonoate + S-adenosyl-L-homocysteine


name: (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + NADPH <=> (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + 5 H(+) + 3 O2 + 6 reduced [adrenodoxin] = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + 4 H2O + 6 oxidized [adrenodoxin]


name: Calcium Binds Caldesmon (Caenorhabditis elegans)


name: alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose => alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: STAT3 binds activated MET receptor (Homo sapiens)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Rattus norvegicus)


name: (11Z)-eicosenoate + sphinganine => H2O + N-(11Z-eicosenoyl)-sphinganine


name: 3-hydroxyhispidin + H2O + NAD(+) => H(+) + hispidin + NADH + O2


name: 3,4-dihydroxybenzoyl-5'-AMP + holo-[aryl-carrier protein] = 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + H(+)


name: IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Mus musculus)


name: ATAT acetylates microtubules (Mus musculus)


name: 3'-phosphoadenylyl sulfate + quercetin <=> adenosine 3',5'-bisphosphate + H(+) + quercetin 3-sulfate


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Mus musculus)


name: (R)-glycerate + ADP-alpha-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-octadecyl-sn-glycero-3-phosphocholine => 1-O-octadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: G alpha (z) inhibits adenylate cyclase (Homo sapiens)


name: p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol (Mus musculus)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Drosophila melanogaster)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Xenopus tropicalis)


name: 2-dehydro-D-glucose + H2O2 + L-alanine => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-alanine + O2


name: p-S215 FOXO3 translocates to the nucleus (Danio rerio)


name: 4-hydroxyestrone + O2 <=> (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+)


name: H(+)(out) + inosine(in) = H(+)(in) + inosine(out)


name: α1-antagonists bind ADRA1A,B,D (Mus musculus)


name: P4HB mediates disulfide bond formation in Proinsulin (Canis familiaris)


name: androstan-3alpha,17beta-diol + NAD(+) => 17beta-hydroxyandrostanone + H(+) + NADH


name: angiotensin I + H2O = angiotensin II + L-histidyl-L-leucine


name: Localization of CBL:GRB2 to the membrane (Homo sapiens)


name: Autophosphorylation of LYN kinase (Drosophila melanogaster)


name: Exogenous soluble antigen targeted to more stable early endosome (Danio rerio)


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Mus musculus)


name: apo-[D-alanyl-carrier protein] + CoA <=> adenosine 3',5'-bisphosphate + H(+) + holo-[D-alanyl-carrier protein]


name: RNA-(apurinic or apyrimidinic site) endonuclease activity


name: ATP + sphing-4-enine => ADP + H(+) + sphing-4-enine 1-phosphate


name: CCND1 recruits HDAC4 to RUNX3 (Canis familiaris)


name: L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Serum albumin binds 2-lysophosphatidylcholine (Sus scrofa)


name: MRE11 binds cytosolic DNA (Xenopus tropicalis)


name: RUNX3 translocates to the nucleus (Drosophila melanogaster)


name: a 1,2-diacylglycerol + a fatty acid + H(+) => a triacyl-sn-glycerol + H2O


name: ATP + pyridoxamine <=> ADP + H(+) + pyridoxamine 5'-phosphate


name: hydroxyproline O-arbinofuranose transferase activity


name: H(+)(in) + L-arabinose(in) => H(+)(out) + L-arabinose(out)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)


name: acetate + paromamine => 2'-N-acetylparomamine + H2O


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O = L-threonyl-[protein] + N-acetyl-D-galactosamine


name: SUMOylation of HIPK2 with SUMO1 (Dictyostelium discoideum)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Drosophila melanogaster)


name: ALDH3B1 oxidises HXAL to PALM (Dictyostelium discoideum)


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose => a neolactoside V(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: GGA3 associates with activated MET receptor (Xenopus tropicalis)


name: a 1-acylglycerol + an acyl-CoA = a 1,3-diacylglycerol + CoA


name: TLR4-induced ripoptosome assembly (Gallus gallus)


name: Neogenin binds repulsive guidance molecules (RGDs) (Homo sapiens)


name: ADP + coenzyme F430 + phosphate => 15,17(3)-seco-F430-17(3)-acid + ATP


name: 9H-carbazole + H(+) + NADPH + O2 => 2'-aminobiphenyl-2,3-diol + NADP(+)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Bos taurus)


name: corticosterone + NADP(+) = 11-dehydrocorticosterone + H(+) + NADPH


name: 2-oxoglutarate + deacetoxycephalosporin C + O2 => CO2 + deacetylcephalosporin C + succinate


name: 2 Fe(II)-[cytochrome c] + H(+) + NADP(+) => 2 Fe(III)-[cytochrome c] + NADPH


name: 4'-apo-beta-carotenal + H2O + NAD(+) => 2 H(+) + NADH + neurosporaxanthin


name: Receptor FFAR1 binds free fatty acids (Canis familiaris)


name: RPE dimers isomerise RU5P to XY5P (Dictyostelium discoideum)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Sus scrofa)


name: 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-[malonate decarboxylase ACP] => diphosphate + holo-[malonate decarboxylase ACP]


name: MAD2 associates with the Mad1 kinetochore complex (Homo sapiens)


name: AGK:Mg2+ phosphorylates MAG, DAG (Drosophila melanogaster)


name: Abortive termination of elongation after arrest (Gallus gallus)


name: sequestered tissue factor -> tissue factor (Homo sapiens)


name: oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor


name: H(+) + 2 H2O + neoechinulin A + oxidized [NADPH--hemoprotein reductase] => O2 + preechinulin + reduced [NADPH--hemoprotein reductase]


name: 2-deoxy-alpha-D-ribose 1-phosphate + uracil => 2'-deoxyuridine + phosphate


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Rattus norvegicus)


name: H2O + spheroiden-2-one => 2,2-dihydroxyspheroidene


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Drosophila melanogaster)


name: oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor


name: AMP + H(+) + NADH + phosphate => (6S)-NADHX + ADP


name: RRAGC,D exchanges GTP for GDP (Saccharomyces cerevisiae)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Homo sapiens)


name: RFK:Mg2+ phosphorylates RIB (Canis familiaris)


name: a medium-chain 2,3-saturated fatty acyl-CoA + O2 <=> a medium-chain (2E)-enoyl-CoA + H2O2


name: 2,6-dihydroxypyridine + H(+) + NADH + O2 = 2,3,6-trihydroxypyridine + H2O + NAD(+)


name: Phosphopantetheine conjugation of the ACP domain of FAS (Sus scrofa)


name: (2E,6E)-farnesol + NAD(+) <=> (2E,6E)-farnesal + H(+) + NADH


name: Release of SEPT4 from mitochondria (Saccharomyces cerevisiae)


name: a 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+)


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Sus scrofa)


name: Activation of IKK complex (Homo sapiens)


name: (R)-acetoin + H(+) + NADH => (R,R)-butane-2,3-diol + NAD(+)


name: 2 H(+) + H2O + N-hydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase] => L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 (Homo sapiens)


name: adenosine 3',5'-bisphosphate + H(+) + L-tyrosine methyl ester 4-sulfate => 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Mus musculus)


name: 12 H(+) + 6 malonyl-CoA + NADH + 5 NADPH <=> (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + 6 CO2 + 6 CoA + 4 H2O + NAD(+) + 5 NADP(+)


name: SFTPA genes produce SFTPA proteins (Homo sapiens)


name: Active FLT3 binds to ABL2 (Mus musculus)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Mus musculus)


name: ATP + H2O + L-aspartate(out) = ADP + H(+) + L-aspartate(in) + phosphate


name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid (Homo sapiens)


name: CoA + H(+) + N(6)-butanoyl-L-lysyl-[protein] => butanoyl-CoA + L-lysyl-[protein]


name: FFAR1:FFAR1 ligands activate Gq (Bos taurus)


name: PCSK9 binds PCSK9 inhibitors (Schizosaccharomyces pombe)


name: CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate => 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + O2


name: Protein Kinase B/Akt phosphorylates BRF1 (Mus musculus)


name: ALOX12 oxidises LTA4 to LXA4/B4 (Homo sapiens)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Rattus norvegicus)


name: glycosylated-ACE2 binds ACE2 inhibitors (Homo sapiens)


name: Clathrin recruits PIK3C2A (Homo sapiens)


name: malvidin + UDP-alpha-D-glucose = malvidin 3-O-beta-D-glucoside + UDP


name: 2 4-sulfanylbutanoate + NAD(+) <=> 4,4'-disulfanyldibutanoate + H(+) + NADH


name: PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex (Drosophila melanogaster)


name: protein-glutamic acid ligase activity, elongating


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + H(+) + phosphate


name: UROD decarboxylates URO1 to COPRO1 (Mus musculus)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Caenorhabditis elegans)


name: The distal appendage proteins recruit TTBK2 (Mus musculus)


name: allo-aromadendrene + diphosphate => (2E,6E)-farnesyl diphosphate


name: PAF receptor binds platelet activating factor (Mus musculus)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Danio rerio)


name: (S)-N-methylbulbocapnine + H(+) + S-adenosyl-L-homocysteine => (S)-bulbocapnine + S-adenosyl-L-methionine


name: 3-dehydro-D-glucose 6-phosphate + L-glutamate = 2-oxoglutarate + D-kanosamine 6-phosphate


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Sus scrofa)


name: 3-chloroallyl aldehyde dehydrogenase activity


name: PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: NADP(+) + prostaglandin I2 <=> 15-dehydro-prostaglandin I2 + H(+) + NADPH


name: 19-(4-hydroxyphenyl)nonadecanoate + ATP + H(+) => 19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + diphosphate


name: 3-bromo-2-heptyl-1-methoxy-4(1H)-quinolinone + H(+) + S-adenosyl-L-homocysteine => 3-bromo-2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine


name: Phosphorylated MAPKs translocate into the nucleus (Dictyostelium discoideum)


name: [(1->4)-alpha-D-glucosyl](n) + an NDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + a ribonucleoside 5'-diphosphate + H(+)


name: PIAS2,3,4 SUMOylate RORA with SUMO1 (Sus scrofa)


name: Degradation of multiubiquitinated Nek2A (Rattus norvegicus)


name: 2 H(+) + hexadecanoyl-CoA + malonyl-CoA + methylmalonyl-CoA = 4-hydroxy-5-methyl-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA


name: (R)-3,3-dimethylmalate + 2 H(+) + NADH => (R)-4-dehydropantoate + H2O + NAD(+)


name: SERPING1 is secreted (Caenorhabditis elegans)


name: ATP + N(8)-citryl-spermidine + spermidine = AMP + diphosphate + H(+) + N(8),N'(8)-citryl-bis(spermidine)


name: ARMS is phosphorylated by active TrkA receptor (Xenopus tropicalis)


name: 5-nitrosalicylate + O2 = 4-nitro-6-oxohepta-2,4-dienedioate + H(+)


name: L-methionine + propanoyl-CoA <=> CoA + H(+) + N-propanoyl-L-methioninate


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Bos taurus)


name: ADP + ecdysone 22-phosphate + H(+) => ATP + ecdysone


name: H2O + N(4)-(ADP-D-ribosyl)-L-asparaginyl-[protein] <=> ADP-D-ribose + L-asparaginyl-[protein]


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Canis familiaris)


name: H(+) + hexadecanal + NADPH => hexadecan-1-ol + NADP(+)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Sus scrofa)


name: MCM8 mediated fork unwinding (Homo sapiens)


name: N-decanoyl-(2S)-hydroxyglycine => decanamide + glyoxylate


name: H(+) + N,N-dihydroxy-L-tryptophan = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + H2O


name: MDM2 SUMOylates TP53 with SUMO2,3 (Homo sapiens)


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Drosophila melanogaster)


name: CoA + H(+) + mycothiol => 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA


name: L-Glutamine transport into neurons (Rattus norvegicus)


name: IRAK interacts with TRAF6 (Xenopus tropicalis)


name: IAP2:BEN:UEV1A E3 ligase complex auto-ubiquitinates (Drosophila melanogaster)


name: H(+) + NADPH + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose <=> NADP(+) + UDP-2-acetamido-2,6-dideoxy-beta-L-talose


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Danio rerio)


name: (2R)-3-phospho-glyceroyl phosphate + [phosphate](n) <=> (2R)-3-phosphoglycerate + [phosphate](n+1)


name: PAK1 or PAK2 phosphorylates MYLK (Canis familiaris)


name: PRKCI phosphorylates ELF3 (Homo sapiens)


name: LTA4 is hydolysed to LTB4 by LTA4H (Canis familiaris)


name: PAN2-PAN3 complex partially deadenylates mRNA (Homo sapiens)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Mus musculus)


name: RHOA GAPs stimulate RHOA GTPase activity (Xenopus tropicalis)


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-2-acetyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Rattus norvegicus)


name: 2-all-trans-heptaprenylphenol + H(+) + NADPH + O2 = 3-(all-trans-heptaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: (7S)-salutaridinol + NADP(+) <=> H(+) + NADPH + salutaridine


name: ERBB4s80 binds ADAP1 gene (Homo sapiens)


name: p-PKR dimer phosphorylates MKK6 (Danio rerio)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Danio rerio)


name: 6-acetyl-D-glucose + H2O <=> acetate + D-glucose + H(+)


name: SIRT1,SIRT3 deacetylate FOXO3 (Gallus gallus)


name: 4-phosphooxy-L-aspartyl-tRNA(Asn) + NH4(+) <=> H(+) + L-asparaginyl-tRNA(Asn) + phosphate


name: 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-(9Z-octadecenoyl)-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Homo sapiens)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: PHF8 demethylates histone H4K20me1 (Danio rerio)


name: ADP(out) + dADP(in) => ADP(in) + dADP(out)


name: Dephosphorylation of Lck-pY505 by CD45 (Canis familiaris)


name: acetyl-CoA + ergosta-5,7,22,24(28)-tetraen-3beta-ol <=> CoA + ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Sus scrofa)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Mus musculus)


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Rattus norvegicus)


name: Aggresome dissociates from dynein and microtubule (Bos taurus)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Schizosaccharomyces pombe)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Rattus norvegicus)