name: 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 2 O2


name: chloride + FADH2 + L-tryptophan + O2 <=> 7-chloro-L-tryptophan + FAD + 2 H2O


name: phenylethanolamine + S-adenosyl-L-methionine <=> H(+) + N-methylphenylethanolamine + S-adenosyl-L-homocysteine


name: CDK1 phosphorylates NUP98 (Mus musculus)


name: Active Rac1 interacts with Plexin-B1:Sema4D (Sus scrofa)


name: 9-cis-10'-apo-beta-carotenal + beta-ionone => 9-cis-beta-carotene + O2


name: 3-oxodecanoyl-[ACP] + CO2 + CoA => H(+) + malonyl-[ACP] + octanoyl-CoA


name: (9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + H(+) + UDP => 17-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose


name: NADPH transfers electrons to FDXR (Mus musculus)


name: benzoyl-CoA + 2 H(+) + 3 malonyl-CoA <=> 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA


name: Trafficking of GluR2-containing AMPA receptors to synapse (Sus scrofa)


name: A + cob(I)alamin + 2 H(+) => AH2 + cob(III)alamin


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Bos taurus)


name: (9E)-octadecenoyl-CoA + hexadecan-1-ol = CoA + hexadecanyl (9E)-octadecenoate


name: Phosphorylation and activation of PLCG (Homo sapiens)


name: LRIG1 undergoes ubiquitination (Homo sapiens)


name: carbovir + IMP => carbovir monophosphate + inosine (Sus scrofa)


name: 2-hydroxy-1-phenyl-1-propanone + NADP(+) <=> 1-phenyl-1,2-propanedione + H(+) + NADPH


name: RIC1:RGP1 recruits RAB6:GDP to the TGN (Gallus gallus)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)


name: H(+) + N(5)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine => L-arginyl-[protein] + S-adenosyl-L-methionine


name: AGRN binds Beta amyloid fibril via GAG chains (Rattus norvegicus)


name: H2O + kynurenate + L-cysteine => 2-oxo-3-sulfanylpropanoate + L-kynurenine


name: O2 + reduced [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha-yl acetate <=> 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MTA is cleaved and phosphorylated (Mus musculus)


name: 4-aminobenzoate + 2 H(+) + NADPH + O2 <=> 4-aminophenol + CO2 + H2O + NADP(+)


name: a 5-methyluridine in RNA + H(+) + S-adenosyl-L-homocysteine => a uridine in RNA + S-adenosyl-L-methionine


name: 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + H(+) + NADH => (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA + NAD(+)


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine => H(+) + kanamycin X + UDP


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Plasmodium falciparum)


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Homo sapiens)


name: formononetin + O2 + reduced [NADPH--hemoprotein reductase] = 2'-hydroxyformononetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HDHD1:Mg2+ dephosphorylates PURIDP (Rattus norvegicus)


name: a fatty acid(out) + ATP(in) + CoA(in) + H(+)(out) = a fatty acyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: acetyl-CoA + CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate <=> CMP-5'-(N-acetyl-N-hydroxy-3-aminopropyl)phosphonate + CoA


name: NADP(+) + prostaglandin F2alpha <=> H(+) + NADPH + prostaglandin H2


name: Phosphorylated Cdc6 is exported from the nucleus (Danio rerio)


name: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate => aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate


name: H(+)(in) + melibiose(in) = H(+)(out) + melibiose(out)


name: CTP(in) + UTP(out) => CTP(out) + UTP(in)


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Rattus norvegicus)


name: MLCL is acylated to CL by HADH (IM) (Sus scrofa)


name: acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein]


name: tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity


name: H(+) + O-phospho-L-serine = CO2 + phosphoethanolamine


name: 2 Fe(III)-[cytochrome c] + hydroxylamine <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + nitroxyl


name: SHC1 bound to IL2 receptor is phosphorylated (Homo sapiens)


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate = 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate


name: (2-aminobenzyl)malonyl-CoA + H(+) + O2 = (E)-2-aminocinnamoyl-CoA + CO2 + H2O2


name: 1-methyladenosine + H2O <=> 1-methyladenine + D-ribose


name: PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL4 complex (Bos taurus)


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Drosophila melanogaster)


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Danio rerio)


name: arginine + H2O => ornithine + urea [ARG1] (Caenorhabditis elegans)


name: GNRHR binds GNRHR peptide agonists (Mus musculus)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 <=> N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-taurine


name: Activated TrkA receptor internalizes to endosomes (Rattus norvegicus)


name: fumarate(out) + 3 H(+)(out) = fumarate(in) + 3 H(+)(in)


name: festuclavine + NAD(+) <=> 6,8-dimethyl-6,7-didehydroergoline + H(+) + NADH


name: dihydrocurcumin + NADP(+) <=> curcumin + H(+) + NADPH


name: ATG3 transfers LC3 from ATG7 to ATG3 (Xenopus tropicalis)


name: (R)-adrenaline + H(+) + S-adenosyl-L-homocysteine => (R)-noradrenaline + S-adenosyl-L-methionine


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Drosophila melanogaster)


name: Transphosphorylation of pLIMK1 (Danio rerio)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + AH2 + fumitremorgin B + 2 O2 => A + CO2 + H2O + succinate + verruculogen


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Mus musculus)


name: ALDH4A1 oxidises L-GluSS to Glu (Mus musculus)


name: 4-pyridoxate + NAD(+) => 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H(+) + NADH


name: Joining of adjacent Okazaki fragments (Bos taurus)


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Bos taurus)


name: dimethylallyl diphosphate + H2O + yaequinolone E => [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate


name: 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate => H2O + ML-236C carboxylate


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Danio rerio)


name: a (9Z)-hexadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (9Z,12E)-hexadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a 1,2-diacyl-sn-glycerol + a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base


name: FGFR4 binds HS:KLB:FGF19 (Drosophila melanogaster)


name: RIP2 is K63 polyubiquitinated (Mus musculus)


name: HOXD1 gene is transcribed (Homo sapiens)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-O-hexadecyl-sn-glycero-3-phosphocholine => 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: DCXR tetramer reduces L-xylulose to xylitol (Xenopus tropicalis)


name: 5-methylcytidine(48) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine => cytidine(48) in tRNA(Asp) + S-adenosyl-L-methionine


name: N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Saccharomyces cerevisiae)


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Canis familiaris)


name: H2O + O2 + S-sulfanylglutathione => glutathione + 2 H(+) + sulfite


name: H2O + N(6)-(2E)-butenoyl-L-lysyl-[protein] = (2E)-2-butenoate + L-lysyl-[protein]


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O


name: choline => acetaldehyde + trimethylamine


name: CO2 + grixazone B + 4 H2O => 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2


name: 3,4-dihydroxyphenylacetate + H(+) + NADH + O2 = 2,4,5-trihydroxyphenylacetate + H2O + NAD(+)


name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Gallus gallus)


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Sus scrofa)


name: an [alpha-factor](in) + ATP + H2O <=> ADP + an [alpha-factor](out) + H(+) + phosphate


name: L-dopa + O2 <=> 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)


name: a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate => 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2


name: ATP + glycyl-L-methionine(out) + H2O => ADP + glycyl-L-methionine(in) + H(+) + phosphate


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Mus musculus)


name: a beta-D-galactoside + acetyl-CoA = a 6-acetyl-beta-D-galactoside + CoA


name: pseudouridine(2605) in 23S rRNA => uridine(2605) in 23S rRNA


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Rattus norvegicus)


name: cumene hydroperoxide + 2 glutathione <=> 2-phenylpropan-2-ol + glutathione disulfide + H2O


name: P4HB:4-Hyp collagen propeptides dissociates (Canis familiaris)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Danio rerio)


name: NEIL3 cleaves thymine glycol from telomeric DNA (Homo sapiens)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Saccharomyces cerevisiae)


name: 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + 5 CoA + H2O => 4 H(+) + 5 malonyl-CoA


name: (+)-cis-trans-nepetalactol + O2 + reduced [NADPH--hemoprotein reductase] => 7-deoxyloganetic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SBF1 binds MTMR2 (Saccharomyces cerevisiae)


name: 2 H2O + L-1-piperideine-6-carboxylate + NADP(+) => H(+) + L-2-aminoadipate + NADPH


name: Conversion of malonyl-CoA and acetyl-CoA to palmitate (Sus scrofa)


name: Transport of the export-competent mRNP complex through the NPC (Sus scrofa)


name: PKC phosphorylates sphingosine kinase 1 (Caenorhabditis elegans)


name: 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine => 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Sus scrofa)


name: 2 A + glycine => 2 AH2 + CO2 + hydrogen cyanide


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Mus musculus)


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Bos taurus)


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Mus musculus)


name: BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose (Bos taurus)


name: an isothiocyanate + sulfate => a (Z)-N-(sulfonatooxy)alkanimidothioate


name: 1-octanoyl-sn-glycero-3-phosphocholine = 1-octanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: (2E,6E,10E)-geranylgeraniol + ATP = (2E,6E,10E)-geranylgeranyl phosphate + ADP + H(+)


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out) => 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in)


name: beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol => cholesteryl 3-beta-D-glucoside + N-dodecanoylsphing-4-enine


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: a thiol + S-adenosyl-L-methionine <=> a methyl thioether + H(+) + S-adenosyl-L-homocysteine


name: (9Z)-octadecenoyl-CoA + FAD + H(+) => (2E,9Z)-octadecadienoyl-CoA + FADH2


name: SLC52A1,2,3 transport RIB from extracellular region to cytosol (Homo sapiens)


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Rattus norvegicus)


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA <=> (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA + H2O


name: PPTN11 dephosphorylates SPRY2 (Homo sapiens)


name: ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine <=> (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine


name: 4-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => estrone + O2 + reduced [NADPH--hemoprotein reductase]


name: myricetin + UDP-beta-L-rhamnose = H(+) + myricetin 3-O-alpha-L-rhamnoside + UDP


name: Plasma membrane glycoconjugates translocate to the cytosol (Homo sapiens)


name: Tyrosine is hydroxylated to dopa (Canis familiaris)


name: TDP1 and TDP2 process unligatable DSB ends (Bos taurus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: 9-cis-10'-apo-beta-carotenal + 2 O2 => (11R)-carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal


name: cis-trans-nepetalactone + H(+) + NADH => cis-trans-nepetalactol + NAD(+)


name: PGM1:Mg2+ isomerises G1P to G6P (Rattus norvegicus)


name: 2-dehydro-D-erythronate + H(+) + NADH => D-erythronate + NAD(+)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Rattus norvegicus)


name: MDM2 translocates to the cytosol (Xenopus tropicalis)


name: FRAT proteins bind GSK3beta (Gallus gallus)


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Mus musculus)


name: IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Canis familiaris)


name: O2 + phenylacetonitrile + reduced [NADPH--hemoprotein reductase] = (R)-mandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PLK1 phosphorylates GORASP1 (Caenorhabditis elegans)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexanoyl-CoA <=> 1-hexadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + CoA


name: Localization of CBL:GRB2 to the membrane (Caenorhabditis elegans)


name: D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+) = diphosphate + GDP-D-glycero-alpha-D-manno-heptose


name: 2 Fe(2+) + 4 H2O + O2 <=> 6 H(+) + H2O2 + 2 iron(III) oxide-hydroxide


name: Aquaporin-7 passively transports glycerol out of cell (Caenorhabditis elegans)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Danio rerio)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Xenopus tropicalis)


name: chorismate <=> 4-hydroxybenzoate + pyruvate


name: Activated FGFR3 phosphorylates FRS2 (Canis familiaris)


name: 4beta-methylzymosterol-4alpha-carboxylate + NADP(+) = 3-dehydro-4-methylzymosterol + CO2 + NADPH


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Canis familiaris)


name: L-histidyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine


name: Extension of pseudopodia by myosin-X in a PI3K dependent manner (Mus musculus)


name: glycine + L-alanine => H2O + L-alanylglycine


name: "phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase"


name: cytidine 5'-diphosphoramidate + H(+) + L-glutamate => H2O + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine


name: Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Caenorhabditis elegans)


name: DAkt1-mediated phosphorylation inactivates DFOXO (Drosophila melanogaster)


name: CoA + O-decanoyl-(R)-carnitine => (R)-carnitine + decanoyl-CoA


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl isothiocyanate + sulfate


name: Integrator complex processes the 3' end of snRNA (Dictyostelium discoideum)


name: (E)-4-hydroxynon-2-enoate + 2 H(+) + NADH => (E)-4-hydroxynon-2-enal + H2O + NAD(+)


name: H2O + o-orsellinate depside = H(+) + 2 orsellinate


name: ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + H(+) + lipid A-core


name: (R)-2-hydroxyglutarate + NAD(+) <=> 2-oxoglutarate + H(+) + NADH


name: all-trans-5,6-epoxyretinoyl-1-O-(beta-D-glucuronate) + UDP => all-trans-5,6-epoxyretinoate + UDP-alpha-D-glucuronate


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)


name: Activated ATM phosphorylates ABL1 (Drosophila melanogaster)


name: (2E)-geranyl diphosphate => (-)-car-3-ene + diphosphate


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate


name: Deacetylation of cleaved cohesin (Homo sapiens)


name: methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Homo sapiens)


name: Caspase-9 binds DCC:DIP13alpha complex (Rattus norvegicus)


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Gallus gallus)


name: ATP + N(6)-(D-erythrulosyl)-L-lysine = ADP + H(+) + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysine


name: MAF1 translocates to the nucleus (Dictyostelium discoideum)


name: Type II receptor phosphorylates type I receptor (Xenopus tropicalis)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Bos taurus)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Homo sapiens)


name: SERPINA6 binds PREDL (Drosophila melanogaster)


name: dCMP + 2 H(+) + 2 phosphate => dCTP + 2 H2O


name: Regeneration of eEF1A:GTP by eEF1B activity (Schizosaccharomyces pombe)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Sus scrofa)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Dictyostelium discoideum)


name: STAT1 and STAT3 dimers translocate to the nucleus (Caenorhabditis elegans)


name: NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Canis familiaris)


name: HSP70 binds to HSP40:nascent protein (Gallus gallus)


name: (S)-dihydroorotate + ubiquinone-8 => orotate + ubiquinol-8


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Danio rerio)


name: L-histidinol + NAD(+) => H(+) + L-histidinal + NADH


name: chloride(out) + L-glutamine(out) + 2 Na(+)(out) <=> chloride(in) + L-glutamine(in) + 2 Na(+)(in)


name: glycyl-5'-AMP + holo-[peptidyl-carrier protein] <=> AMP + glycyl-[peptidyl-carrier protein] + H(+)


name: Loading of PCNA - Sliding Clamp Formation (Bos taurus)


name: C20 sphinganine + phosphate => C20 sphinganine 1-phosphate + H2O


name: Hydrolysis of PIP2 by PLCG (Canis familiaris)


name: POU5F1 (OCT4), SOX2, NANOG bind the TDGF1 promoter (Homo sapiens)


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Rattus norvegicus)


name: TRAF1 binds TRAF2 within TNFR1 signaling complex (Sus scrofa)


name: lathosterol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha,8alpha-epoxy-5alpha-cholestan-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: steviolbioside + UDP-alpha-D-glucose => stevioside + UDP


name: protein tyrosine/serine/threonine phosphatase activity


name: 17alpha-hydroxypregnenolone + O2 + reduced [NADPH--hemoprotein reductase] => 3beta-hydroxyandrost-5-en-17-one + acetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TTR:RBP:atROL binds to STRA6 receptor (Rattus norvegicus)


name: 4-hydroxy-L-proline(out) + chloride(out) + 2 Na(+)(out) => 4-hydroxy-L-proline + chloride(in) + 2 Na(+)(in)


name: cytidine(8) in tRNA + H(+) + H2O = NH4(+) + uridine(8) in tRNA


name: p-S54,92,203-BRF1 binds 14-3-3 (Caenorhabditis elegans)


name: desacetylmycothiol is acetylated to mycothiol using acetyl-CoA (Mycobacterium tuberculosis)


name: Syndecan-1 binds fibronectin (Caenorhabditis elegans)


name: I-Smad competes with Co-Smad for R-Smad1/5/8 (Sus scrofa)


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Homo sapiens)


name: MAPK4,6 translocate to the cytoplasm (Homo sapiens)


name: Homodimerization of ERBB4 (Gallus gallus)


name: TRMT13 2'-O-methylates cytidine-4 in tRNA (Homo sapiens)


name: Trans-homodimerization of Neurofascin (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O => a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + H(+) + phosphate


name: (E)-6-hydroxyferuloyl-CoA + CO2 + succinate => (E)-feruloyl-CoA + 2-oxoglutarate + O2


name: (9Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: H2O + NAD(+) + phosphonate <=> H(+) + NADH + phosphate


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Xenopus tropicalis)


name: 2 methanethiol + NAD(+) <=> dimethyl disulfide + H(+) + NADH


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Saccharomyces cerevisiae)


name: 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 32-oxo-24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: aspulvinone E + O2 <=> (5Z)-3-(3,4-dihydroxyphenyl)-5-[(3,4-dihydroxyphenyl)methylidene]-5-oxo-2,5-dihydrofuran-3-olate


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Homo sapiens)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Danio rerio)


name: CMP + ganglioside GD1a (18:1(4E)/18:0) + H(+) => CMP-N-acetyl-beta-neuraminate + ganglioside GM1 (d18:1(4E)/18:0)


name: 1D-myo-inositol 4-phosphate + H2O => myo-inositol + phosphate


name: STAT1 and STAT3 dimers translocate to the nucleus (Homo sapiens)


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Bos taurus)


name: Type X collagen associates with collagen type II fibrils (Sus scrofa)


name: phycocyanobilin-L-cysteinyl(84)-[C-phycocyanin alpha-subunit] <=> (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[C-phycocyanin alpha-subunit]


name: 3-deoxy-alpha-D-manno-oct-2-ulosonate + O2 = 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + H2O2


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Schizosaccharomyces pombe)


name: NCAM1 interacts with T- and L-type VDCC (Homo sapiens)


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Canis familiaris)


name: 2,3-epoxyphylloquinone + A + H2O => AH2 + O2 + phylloquinone


name: RCC1 stimulates GDP to GTP exchange on RAN (Mus musculus)


name: 6-hydroxydeoxybrevianamide E + dimethylallyl diphosphate <=> diphosphate + notoamide S


name: 2''-O-octanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide => H2O + N(6)-octanoyl-L-lysyl-[protein] + NAD(+)


name: ITPA hydrolyses XTP to XMP (Saccharomyces cerevisiae)


name: 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + S-adenosyl-L-methionine <=> 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: ITP + pyruvate = H(+) + IDP + phosphoenolpyruvate


name: 2 aureusidin 6-O-beta-glucoside + 2 H2O => 2 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 2 H(+) + O2


name: Caspase-1 active tetramer formation (Homo sapiens)


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Drosophila melanogaster)


name: chlorophyllide a + H2O => 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Homo sapiens)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Caenorhabditis elegans)


name: GLI2,3 are degraded by the proteasome (Drosophila melanogaster)


name: STAB1:ligand is endocytosed (Mus musculus)


name: α1-agonists bind ADRA1A,B,D (Xenopus tropicalis)


name: uridine(32) in tRNA <=> pseudouridine(32) in tRNA


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2 => 2-dehydro-D-glucose + H2O2 + L-tyrosine


name: CYP3A4 monooxygenates ATV to 2-OH-ATV (Bos taurus)


name: alpha-D-ribose 1-phosphate + hypoxanthine => inosine + phosphate


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Plasmodium falciparum)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Mus musculus)


name: Interaction of Tie2 with Ang2 (Danio rerio)


name: (S)-corytuberine + 2 H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase]


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Canis familiaris)


name: Interaction of integrin alphaDbeta2 with fibrin (Sus scrofa)


name: 4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine <=> 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + H(+) + S-methyl-5'-thioadenosine


name: ADP + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => ADP-L-glycero-beta-D-manno-heptose + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A


name: MBTPS1 (S1P) cleaves CREB3 (Homo sapiens)


name: 2xENPP1 hydrolyzes FAD to FMN (Bos taurus)


name: acetyl-CoA + fumigaclavine B = CoA + fumigaclavine A


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O => a 1,2-diacyl-sn-glycerol + H(+) + phosphoethanolamine


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Sus scrofa)


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Caenorhabditis elegans)


name: Mevalonate-5-phosphate is further phosphorylated. (Caenorhabditis elegans)


name: A + H2O + N(6)-dimethylallyladenine = 3-methyl-2-butenal + adenine + AH2


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2 => (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Gallus gallus)


name: Hh-Np traffics to the plasma membrane (Canis familiaris)


name: CBL ubiquitinates FRS2 and FGFR3 (Rattus norvegicus)


name: GTP + N-acetyl-D-glucosamine = GDP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: GPCho is hydrolyzed to Cho and G3P by GPCPD1 (Homo sapiens)


name: NEU2 hydrolyzes Neu5Ac from glycoconjugates (Canis familiaris)


name: Thr-180 of ULK1 is phosphorylated (Rattus norvegicus)


name: TFIIH binds GG-NER site to form a verification complex (Bos taurus)


name: HDAC6 deacetylates microtubules (Dictyostelium discoideum)


name: N-myristoylation of eNOS (Drosophila melanogaster)


name: (-)-4'-methoxycyclopenine + CO2 + succinate => (Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2


name: acetyl phosphate + L-lysyl-[protein] <=> H(+) + N(6)-acetyl-L-lysyl-[protein] + phosphate


name: NADPH + 2 oxidized [2Fe-2S]-[protein] = H(+) + NADP(+) + 2 reduced [2Fe-2S]-[protein]


name: Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)


name: UDP-alpha-D-galactose(out) + UDP-alpha-D-glucose(in) => UDP-alpha-D-galactose(in) + UDP-alpha-D-glucose(out)


name: Formation of the MCC complex (Dictyostelium discoideum)


name: 3-oxohexadecanoyl-CoA + H(+) + NADPH = (3R)-hydroxyhexadecanoyl-CoA + NADP(+)


name: (9Z,12Z)-octadecadienoate + O2 <=> (13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: 2-glyceryl-prostaglandin H2 = 2-glyceryl-prostaglandin D2


name: (S)-lactate(in) + Na(+)(in) => (S)-lactate(out) + Na(+)(out)


name: cyclohexylamine + H2O + O2 = cyclohexanone + H2O2 + NH4(+)


name: Interaction of MyoD:E protein with MEF2 (Caenorhabditis elegans)


name: (20S)-ginsenoside Rh2 + D-glucose => (20S)-ginsenoside Rg3 + H2O


name: Thrombin-activated PARs:G12/13 (active) dissociate (Canis familiaris)


name: 1-deoxy-11beta-hydroxypentalenate + NAD(+) => 1-deoxy-11-oxopentalenate + H(+) + NADH


name: beta-alanyl-[peptidyl-carrier protein] + tryptamine => beta-alanyl-tryptamine + H(+) + holo-[peptidyl-carrier protein]


name: Trimerization of cytosolic HSF1 (Canis familiaris)


name: UBQLNs bind UIM-containing adaptor proteins (Homo sapiens)


name: [amino-group carrier protein]-C-terminal-L-glutamate + ATP + L-2-aminoadipate = [amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ADP + H(+) + phosphate


name: "[amino-group carrier protein]--L-2-aminoadipate ligase"


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Xenopus tropicalis)


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Homo sapiens)


name: Conversion of glyoxylate to oxalate (Mus musculus)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Sus scrofa)


name: an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol = 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Bos taurus)


name: STING ubiquitination by TRIM32 or TRIM56 (Danio rerio)


name: "N-terminal amino-acid N(alpha)-acetyltransferase NatA"


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Gallus gallus)


name: 2-hydroxy-2,3-dihydrogenistein = genistein + H(+) + H2O


name: H(+)(in) + sulfate(in) <=> H(+)(out) + sulfate(out)


name: 26-hydroxyhexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 26-oxohexacosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: KAT5 acetylates ATM at shortened telomeres (Dictyostelium discoideum)


name: 8 (S)-methylmalonyl-CoA + 24 H(+) + hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 16 NADPH = C40-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+)


name: 2-oxoglutarate + L-enduracididine + O2 <=> (3S)-3-hydroxy-L-enduracididine + CO2 + succinate


name: DHI and DHICA polymerize forming eumelanin (Canis familiaris)


name: ecdysone 22-phosphate + H2O => ecdysone + phosphate


name: Dephosphorylation of p107 (RBL1) by PP2A (Homo sapiens)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Rattus norvegicus)


name: PNP trimer transforms RBV to T-CONH2 (Schizosaccharomyces pombe)


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Sus scrofa)


name: chondroitin 4'-sulfate => dermatan 4'-sulfate


name: cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Rattus norvegicus)


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Danio rerio)


name: aspulvinone E + O2 => (5Z)-3-(3,4-dihydroxyphenyl)-5-[(3,4-dihydroxyphenyl)methylidene]-5-oxo-2,5-dihydrofuran-3-olate


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Rattus norvegicus)


name: STUB1 ubiquitinates RIPK3 at K55, K363 (Bos taurus)


name: 2-oxoglutarate(in) + prostaglandin E2(out) = 2-oxoglutarate(out) + prostaglandin E2(in)


name: all-trans-hexaprenyl diphosphate => diphosphate + talaropentaene


name: H2O + N-(dodecanoyl)-sphinganine => dodecanoate + sphinganine


name: a 3alpha-hydroxy bile acid CoA + NAD(+) => a 3-oxo bile acid CoA + H(+) + NADH


name: low-affinity nitrate transmembrane transporter activity


name: an N-(acyl)-sphingosylphosphocholine(in) => an N-(acyl)-sphingosylphosphocholine(out)


name: IL21 receptor STAT phosphorylation (Bos taurus)


name: 3-dimethylallyl-4-hydroxymandelate + O2 = 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O


name: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => (+)-penichrysol + diphosphate


name: Phosphorylation and activation of VAV (Xenopus tropicalis)


name: factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) (Gallus gallus)


name: 2 Na(+)(out) + scyllo-inositol(out) => 2 Na(+)(in) + scyllo-inositol(in)


name: 2 Fe(2+) + 2 H2O + H2O2 <=> 6 H(+) + 2 iron(III) oxide-hydroxide


name: GABA loaded synaptic vesicle Docking and Priming (Drosophila melanogaster)


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Homo sapiens)


name: 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] = 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MBTPS1 (S1P) cleaves CREB3L3 (Xenopus tropicalis)


name: BP180 interacts intracellularly with plectin and integrin beta4 (Rattus norvegicus)


name: ADCY3:GNAL:GTP converts ATP to cAMP (Homo sapiens)


name: 2-hydroxycyclohexan-1-one + H(+) + NADPH + O2 = 6-hydroxyhexan-6-olide + H2O + NADP(+)


name: 3-O-(beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP => L-seryl-[protein] + UDP-alpha-D-xylose


name: inosine(out) + Na(+)(out) <=> inosine(in) + Na(+)(in)


name: PDGF dimer binds two receptors simultaneously (Caenorhabditis elegans)


name: acetyl-CoA + oxalate => acetate + oxalyl-CoA


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Xenopus tropicalis)


name: 2-oxoglutarate + 3(1)-hydroxy-L-isoleucine + O2 <=> (4S)-3(1),4-dihydroxy-L-isoleucine + CO2 + succinate


name: eicosanoyl-CoA + H(+) + malonyl-CoA => 3-oxodocosanoyl-CoA + CO2 + CoA


name: Carbonic anhydrase hydrates carbon dioxide (cytosol) (Mus musculus)


name: CBFB binds RUNX1 (Caenorhabditis elegans)


name: methanophenazine + reduced coenzyme F420-(gamma-L-Glu)(n) => dihydromethanophenazine + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: 4-coumaroyl-CoA + 2 H(+) + 3 malonyl-CoA => 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoA


name: PDSS1,2 ligates FPP to IPPP (Rattus norvegicus)


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Sus scrofa)


name: (2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine


name: NH4(+) + phenol + pyruvate => H2O + L-tyrosine


name: beta-alanine(out) + n H(+)(in) => beta-alanine(in) + n H(+)(out)


name: Protein Kinase B/Akt phosphorylates BRF1 (Dictyostelium discoideum)


name: PGE2 is converted to PGF2a by CBR1 (Rattus norvegicus)


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Xenopus tropicalis)


name: (3R)-hydroxy-(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA <=> (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H2O


name: Relaxin receptor 1 binds relaxin 2 and 3 (Rattus norvegicus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Mus musculus)


name: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol


name: L-ornithine + pyruvate <=> 5-amino-2-oxopentanoate + L-alanine


name: p-IRF7:p-IRF7 translocates to the nucleus (Sus scrofa)


name: RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)


name: H(+) + NADPH + O2 + phenol => catechol + H2O + NADP(+)


name: Factor H binds to host cell surface (Gallus gallus)


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Rattus norvegicus)


name: NADP(+) + scytalone = H(+) + NADPH + naphthalene-1,3,6,8-tetrol


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Rattus norvegicus)


name: 2-glyceryl-prostaglandin H2 <=> 2-glyceryl-prostaglandin E2


name: an alpha-L-fucoside + H2O <=> an alcohol + L-fucose


name: Phosphorylation of CBL (EGFR:CBL) (Gallus gallus)


name: D-ribulose 5-phosphate + L-tryptophan <=> (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + formaldehyde + H(+) + H2O + hydroxyacetone + phosphate


name: Expression of MINK1/TNIK is positively regulated by ROS (Homo sapiens)


name: (+)-delta-cadinol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: HSP90 binds TBK1 and IRF3 (Rattus norvegicus)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Sus scrofa)


name: ATP + H(+) + L-glutamate + NADPH <=> ADP + L-glutamate 5-semialdehyde + NADP(+) + phosphate


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Rattus norvegicus)


name: H2O + N(6)-methyl-dATP = diphosphate + H(+) + N(6)-methyl-dAMP


name: H2O + N-(15Z-tetracosenoyl)-taurine <=> (15Z)-tetracosenoate + taurine


name: H2O + thiamine => 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)


name: Type B histone acetlytransferase complex acetylates histone H4 (Dictyostelium discoideum)


name: 2-oxoglutarate + L-2,4-diaminobutanoate <=> L-aspartate 4-semialdehyde + L-glutamate


name: H2O + quinolin-4-ol => 3-(2-aminophenyl)-3-oxopropanal


name: Interaction of particulate antigens with dendritic cell receptors (Caenorhabditis elegans)


name: L-arginyl-[protein] + NAD(+) <=> ADP-riboxanated L-argininyl-[protein] + H(+) + NH4(+) + nicotinamide


name: IDUA hydrolyses Heparan sulfate chain(6) (Rattus norvegicus)


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Homo sapiens)


name: anisole + O2 + reduced [NADH--hemoprotein reductase] = formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase] + phenol


name: GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress (Bos taurus)


name: acrolein + hydrogen cyanide <=> (2S)-2-hydroxybut-3-enenitrile


name: NAD(+) + succinate = fumarate + H(+) + NADH


name: (2R,3R)-tartrate + NAD(+) => 2-hydroxy-3-oxosuccinate + H(+) + NADH


name: biochanin A 7-O-beta-D-glucoside 6''-O-malonate + CoA => biochanin A 7-O-beta-D-glucoside + malonyl-CoA


name: STAT binds to the active receptor (Bos taurus)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Saccharomyces cerevisiae)


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Rattus norvegicus)


name: CEBPB homodimerization (Canis familiaris)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Danio rerio)


name: H(+) + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate => L-glutamate + O-phospho-L-serine


name: CoA + tetradecanyl tetradecanoate => tetradecan-1-ol + tetradecanoyl-CoA


name: Release of E3 from polyubiquitinated substrate (Gallus gallus)


name: a menaquinone + 2 H(+) + 2 superoxide => a menaquinol + 2 O2


name: 2-oxoglutarate + mugineate + O2 => 3-epihydroxymugineate + CO2 + H(+) + succinate


name: (9Z,12Z)-octadecadienoyl-CoA + 2-(9Z-octadecenoyl)-glycerol => 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Bos taurus)


name: L-cysteinylglycine + L-glutamate => glutathione + H2O


name: 2 NADPH + palmatine + S-adenosyl-L-methionine <=> corydaline + 2 NADP(+) + S-adenosyl-L-homocysteine


name: ITGA4:ITGB1 binds natalizumab (Homo sapiens)


name: a methyl thioether + H(+) + S-adenosyl-L-homocysteine => a thiol + S-adenosyl-L-methionine


name: DHTKD1 dimer decarboxylates 2-OA (Sus scrofa)


name: 6-methylpretetramide + 2 H(+) + NADPH + O2 <=> 4-hydroxy-6-methylpretetramide + H2O + NADP(+)


name: NEMO binds polyubiquitinated IRAK1 (Mus musculus)


name: CSKMT methylates Citrate Synthase (Sus scrofa)


name: Integrator complex processes the 3' end of snRNA (Danio rerio)


name: IDO1 dioxygenates L-Trp to NFK (Canis familiaris)


name: (2E,6E)-farnesol + CTP = (2E,6E)-farnesyl phosphate + CDP + H(+)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Homo sapiens)


name: (3S)-citramalyl-CoA = H2O + itaconyl-CoA


name: Autocatalytic activation of MMP3 (Mus musculus)


name: N-atom dealkylation of caffeine (Sus scrofa)


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Danio rerio)


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Drosophila melanogaster)


name: ESR1-dependent CCND1 expression (Homo sapiens)


name: L-arginine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) = L-arginine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: 3-hydroxypropanal + H(+) + NADH => NAD(+) + propane-1,3-diol


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Caenorhabditis elegans)


name: DIBOA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-nitrobutanedioate + H2O + NADP(+) => (2S)-2-nitrosobutanedioate + H(+) + NADPH + O2


name: cya and lef bind to pagA(197-794):ANTXR1 oligomer (Homo sapiens)


name: EML4 binds to microtubules (Rattus norvegicus)


name: Activation of proMMP9 by proteases (Danio rerio)


name: Formation of the cap-binding eIF4F complex (Dictyostelium discoideum)


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Canis familiaris)


name: cytidine(839) in 12S rRNA + S-adenosyl-L-methionine <=> H(+) + N(4)-methylcytidine(839) in 12S rRNA + S-adenosyl-L-homocysteine


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Drosophila melanogaster)


name: 13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+) = 15-oxoprostaglandin E1 + H(+) + NADPH


name: Dimerization of p-S446-IRF5 (Mus musculus)


name: Methylthio-ribose-P = Methylthio-ribulose-P (Mus musculus)


name: PAK1-3 dimer disassociates (Xenopus tropicalis)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Drosophila melanogaster)


name: ORC5 binds ORC2:ORC3 (Rattus norvegicus)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 bromide + 3 FADH2 + 3 O2 = (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 FAD + 6 H2O


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate = (+)-cubenene + diphosphate


name: Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Mus musculus)


name: H2O + N-deacetylisoipecoside = D-glucose + N-deacetylisoipecoside aglycone


name: BRD7 binds TP53 and EP300 (Drosophila melanogaster)


name: 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 <=> 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Homo sapiens)


name: SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: RHOA:GTP translocates to the ER membrane (Schizosaccharomyces pombe)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+) + octadecanoate


name: DENND4s exchange GTP for GDP on RAB10 (Mus musculus)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Schizosaccharomyces pombe)


name: 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA => 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA


name: (3R)-vestitone + NADP(+) => 2'-hydroxyformononetin + 2 H(+) + NADPH


name: chloroorienticin B + dTDP-beta-L-vancosamine <=> chloroeremomycin + dTDP + H(+)


name: GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Canis familiaris)


name: 2-oxoglutarate + a (3R)-3-[(carboxymethyl)amino]fatty acid + O2 <=> a (3R)-3-{[carboxy(hydroxy)methyl]amino}fatty acid + CO2 + succinate


name: calciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> calcidiol + H2O + 2 oxidized [adrenodoxin]


name: POLZ extends translesion synthesis (Sus scrofa)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Sus scrofa)


name: YBX1 binds COL1A2 gene promoter (Homo sapiens)


name: GDP + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n+1) + phosphate => GTP + L-glutamate + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Mus musculus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Homo sapiens)


name: HEYL binds CDH11 gene promoter (Homo sapiens)


name: 2-oxoglutarate + O2 + thebaine => CO2 + formaldehyde + neopinone + succinate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> 7-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: a globoside Gb3Cer (d18:1(4E)) + H2O => a fatty acid + a lysoGb3(d18:1(4E))


name: [thioredoxin]-disulfide + dCDP + H2O => [thioredoxin]-dithiol + CDP


name: 1-O-alkyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-alkyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: H2O + O2 + pyridoxamine => H2O2 + NH4(+) + pyridoxal


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Bos taurus)


name: Packaging of Viral Genome Into C Capsids (Homo sapiens)


name: C3d-complexed antigen binds to complement receptor (Bos taurus)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Dictyostelium discoideum)


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Rattus norvegicus)


name: Initial activation of proMMP2 by MMP14 (Canis familiaris)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Sus scrofa)


name: 3-phenylpyruvate + L-kynurenine = H2O + kynurenate + L-phenylalanine


name: 2-oxoglutarate + [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate <=> [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + L-glutamate


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Homo sapiens)


name: RAC1 and CDC42 activate PAK1 (Gallus gallus)


name: F-actin capping protein is a heterodimer (Homo sapiens)


name: eIF5B:GTP is hydrolyzed and released (Saccharomyces cerevisiae)


name: p-S10 CDKN1B translocates to the cytosol (Drosophila melanogaster)


name: SUMOylation of ING2 with SUMO1 (Sus scrofa)


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)


name: (R)-adrenaline + H2O + O2 => (R)-3,4-dihydroxymandelaldehyde + H2O2 + methylamine


name: Metallochaperone inserts Cu2+ into MT-CO1 (Canis familiaris)


name: 9,10-epoxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-9,10-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + kinetensin = kinetensin-(1-8) + L-leucine


name: CBL neddylates TGFBR2 (Drosophila melanogaster)


name: H2O + tetrathionate <=> H(+) + sulfate + sulfur + thiosulfate


name: 12-hexadecanoyloxy-octadecanoate + H2O <=> 12-hydroxyoctadecanoate + H(+) + hexadecanoate


name: (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O <=> pyruvate + salicylaldehyde


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)


name: SHC1 phosphorylation by phosphorylated EGFR (Homo sapiens)


name: IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Sus scrofa)


name: an aldehyde + 2 Fe(II)-[cytochrome cL] + 2 H(+) => a primary alcohol + 2 Fe(III)-[cytochrome cL]


name: Recruited STAT5 is phosphorylated (Canis familiaris)


name: TNF-α is cleaved by ADAM17 (TACE) (Canis familiaris)


name: Phosphorylated RHOU translocates to the endosome membrane (Danio rerio)


name: 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: (E)-caffeate + ATP + CoA <=> (E)-caffeoyl-CoA + AMP + diphosphate


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + H(+) + phosphate


name: PIDD1 associates with CRADD (Canis familiaris)


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Bos taurus)


name: dopamine + H2O + O2 <=> 3,4-dihydroxyphenylacetaldehyde + H2O2 + NH4(+)


name: GBF1 recruits ARF:GDP to the ERGIC (Drosophila melanogaster)


name: N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Mus musculus)


name: (3R)-hydroxybutanoate tetramer + H2O = (3R)-hydroxybutanoate trimer + (R)-3-hydroxybutanoate + H(+)


name: Oxidative damage to the AP site (Bos taurus)


name: α2-agonists bind ADRA2A,B,C (Bos taurus)


name: protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Sus scrofa)


name: a 3beta-hydroxysteroid + NADP(+) => a 3-oxosteroid + H(+) + NADPH


name: Activation of Rap1 by membrane-associated GEFs (Dictyostelium discoideum)


name: Formation of ERCC1:XPF heterodimeric complex (Sus scrofa)


name: 2-dehydro-3-deoxy-D-glucarate = 2-hydroxy-3-oxopropanoate + pyruvate


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Xenopus tropicalis)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Homo sapiens)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADH + O2 = 4beta-hydroxymethyl-4alpha-methylzymosterol + H2O + NAD(+)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)


name: D-mannitol + NAD(+) = D-mannose + H(+) + NADH


name: Activated ESR1 binds the RUNX2 gene promoter (Homo sapiens)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Rattus norvegicus)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Sus scrofa)


name: (6S)-5,6,7,8-tetrahydrofolate(out) + ATP + H2O <=> (6S)-5,6,7,8-tetrahydrofolate(in) + ADP + H(+) + phosphate


name: Recruitment of IFNAR1 (Canis familiaris)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)


name: H2O + pristanoyl-CoA <=> 2,6,10,14-tetramethylpentadecanoate + CoA + H(+)


name: NPAS4 binds NAMPT gene promoter (Homo sapiens)


name: EDNRA,EDNRB bind EDNs (Rattus norvegicus)


name: WWTR1 (TAZ) binds ZO-2 (TJP2) (Caenorhabditis elegans)


name: Follitropin is a heterodimer (Danio rerio)


name: Membrane estrogen receptors bind SRC (Sus scrofa)


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Bos taurus)


name: ferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => abieta-8,11,13-triene + O2 + reduced [NADPH--hemoprotein reductase]


name: Dissociation of Phospho-Nlp from the centrosome (Bos taurus)


name: SUMOylation of NPM1 with SUMO1 (Bos taurus)


name: CaMKK autophosphorylates in the nucleus (Homo sapiens)


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Bos taurus)


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Xenopus tropicalis)


name: beta-alanine + CO2 + NH4(+) => 3-(carbamoylamino)propanoate + 2 H(+) + H2O


name: PDE3B hydrolyses cAMP to AMP (Homo sapiens)


name: Spontaneous hydrolysis of C3 thioester (Bos taurus)


name: 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2-succinylamino-6-oxoheptanedioate + L-glutamate


name: ALDH4A1 oxidises L-GluSS to Glu (Danio rerio)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: a ribonucleoside 5'-diphosphate + ADP => a ribonucleoside 5'-triphosphate + AMP


name: (R)-4'-phosphopantothenate + CTP + L-cysteine <=> CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine


name: PRKD1,2,3 phosphorylates CERT1-2 (Caenorhabditis elegans)


name: a D-glucoside + NAD(+) = a 3-dehydro-D-glucoside + H(+) + NADH


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + an acyl-CoA


name: (2E,6E)-farnesyl diphosphate => alpha-muurolene + diphosphate


name: ATP + sedoheptulose => ADP + D-sedoheptulose 7-phosphate + H(+)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-oxopropanoyl-CoA + H2O <=> 3-oxopropanoate + CoA + H(+)


name: signaling receptor complex adaptor activity


name: RNA Polymerase II Promoter Opening: First Transition (Rattus norvegicus)


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Dictyostelium discoideum)


name: 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate <=> H2O + xanthurenate


name: voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential


name: Excess cysteine yields lanthionine and H2S (Danio rerio)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Gallus gallus)


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Mus musculus)


name: ZIP6 and ZIP14 mediate zinc influx into cells (Bos taurus)


name: MPI isomerises Fru6P to Man6P (Dictyostelium discoideum)


name: GSTO dimers reduce DeHA to AscH- (Drosophila melanogaster)


name: Transfer of Fe-S clusters to SDHB (Homo sapiens)


name: ATP hydrolysis by HSP70 (Dictyostelium discoideum)


name: STAT1,STAT3,STAT6 phosphorylation (Mus musculus)


name: plastid single subunit type RNA polymerase activity


name: myricetin + S-adenosyl-L-methionine => H(+) + laricitrin + S-adenosyl-L-homocysteine


name: 4 glutathione + 2 H(+) + selenite <=> glutathione disulfide + 3 H2O + selenodiglutathione


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Rattus norvegicus)


name: (3R)-hydroxytriacontanoyl-CoA = (2E)-triacontenoyl-CoA + H2O


name: CREB3L3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Sus scrofa)


name: p38MAPK phosphorylates MSK1 (Canis familiaris)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Homo sapiens)


name: NOTCH precursor cleaved to form mature NOTCH (Gallus gallus)


name: (2R)-3-phosphoglycerate + ADP-alpha-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Caenorhabditis elegans)


name: chloride + H(+) + S-carboxymethyl-L-cysteine => 3-chloro-L-alanine + thioglycolate


name: L-gulono-1,4-lactone + O2 = H(+) + H2O2 + L-ascorbate


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Schizosaccharomyces pombe)


name: MAPK6 is degraded by the 26S proteasome (Saccharomyces cerevisiae)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-phenylalanyl-[tubulin] + H2O <=> C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-phenylalanine


name: 3 AH2 + 2 H(+) + heme b + 3 O2 <=> 3 A + biliverdin IXbeta + CO + Fe(2+) + 3 H2O


name: CANX dissociates from IL12A:EBI3 (Sus scrofa)


name: glutathione + hydrogenselenide + NADP(+) => glutathioselenol + NADPH


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Rattus norvegicus)


name: Cleavage of ethenocytosine by TDG glycosylase  (Sus scrofa)


name: GNLY binds the bacterial cell surface (Danio rerio)


name: 5alpha-androstan-3,17-dione + A <=> AH2 + androst-4-ene-3,17-dione


name: H(+) + isoscopoletin + S-adenosyl-L-homocysteine => esculetin + S-adenosyl-L-methionine


name: H2O + hydroquinone + NAD(+) => H(+) + NADH + O2 + phenol


name: BCMO1:Fe2+ cleaves betaC to atRAL (Mus musculus)


name: Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Bos taurus)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate <=> 15-cis-phytoene + 2 diphosphate


name: Phosphorylated NICD1 binds FBXW7 (Homo sapiens)


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Rattus norvegicus)


name: ALDH8A1 oxidises 9cRAL to 9cRA (Mus musculus)


name: (2S)-2-acetolactate + thiamine diphosphate <=> 2-(1-hydroxyethyl)thiamine diphosphate + pyruvate


name: Interaction of integrin alphaIIb beta3 with Fibrinogen (Drosophila melanogaster)


name: 2 aminomethylphosphonate + 2 glyoxylate + 2 H(+) => 2 glyphosate + O2


name: RDH12 reduces atRAL to atROL (Danio rerio)


name: an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + H2O => an L-N,N-dihydroxypolyhomomethionine + H(+)


name: NEIL3 cleaves thymine glycol (Homo sapiens)


name: 2-dodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl dodecanoate + apo--[retinol-binding protein] => 1,2-didodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein]


name: 4-hydroxy-2-oxoheptanedioate => pyruvate + succinate semialdehyde


name: (R)-pantothenate(out) + 2 Na(+)(out) <=> (R)-pantothenate(in) + 2 Na(+)(in)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoyl-CoA + O2 <=> (14Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Plasmodium falciparum)


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Rattus norvegicus)


name: Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Dictyostelium discoideum)


name: 3-deoxyglucosone + L-lysyl-[protein] + phosphate => H2O + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein]


name: 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 => a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate


name: 11-cis-retinol + a fatty acyl-CoA = 11-cis-retinyl ester + CoA


name: 4 H(+) + 2 O2 + pentalenene + 4 reduced [2Fe-2S]-[ferredoxin] => 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al


name: a guanosine in mRNA + S-adenosyl-L-methionine => an N(7)-methylguanosine in mRNA + S-adenosyl-L-homocysteine


name: ESR-associated SRC autophosphorylates (Bos taurus)


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Canis familiaris)


name: 2-methylfumaryl-CoA + succinate => mesaconate + succinyl-CoA


name: β1,2-agonists bind ADRB1,2 (Danio rerio)


name: 3-phosphonopyruvate => H(+) + phosphoenolpyruvate


name: keto-D-tagatose 6-phosphate = keto-D-fructose 6-phosphate


name: FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + H(+)(in) => (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + H(+)(out)


name: SIRT5 deacetylates Cytochrome C (Xenopus tropicalis)


name: AKT phosphorylates FOXO3 downstream of ESR1 and EGFR (Mus musculus)


name: PIP3 recruits PDPK1 to the membrane (Bos taurus)


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Canis familiaris)


name: ATP + holo-[LYS2 peptidyl-carrier protein] + L-2-aminoadipate => AMP + diphosphate + L-2-aminoadipyl-[LYS2 peptidyl-carrier protein]


name: a fatty acid + H(+) + long chain 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol => H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: CYP4F3 20-hydroxylates LTB4 (Danio rerio)


name: anthocyanin A9 + CoA => anthocyanin A7 + malonyl-CoA


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Danio rerio)


name: 10-oxo-(11E)-octadecenoate + H(+) + NADH => 10-oxooctadecanoate + NAD(+)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Xenopus tropicalis)


name: SALL4 recruits NuRD to PTEN gene (Mus musculus)


name: Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG (Sus scrofa)


name: H2O + isomaltose = alpha-D-glucose + D-glucose


name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression (Homo sapiens)


name: Formation of fatty acid synthase (FAS) dimer (Caenorhabditis elegans)


name: (S)-malyl alpha-D-glucosaminide + acetate => (S)-malyl N-acetyl-alpha-D-glucosaminide + H2O


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Sus scrofa)


name: NTRK2 activates RAS signaling through FRS2 (Homo sapiens)


name: PON1,3 hydrolyse ATVL to ATV (Rattus norvegicus)


name: IGFBP6 binds IGF forming IGF:IGFBP6 (Homo sapiens)


name: (2R)-2,3-bisphosphoglycerate + ATP + H(+) <=> ADP + cyclic (2R)-2,3-bisphosphoglycerate + phosphate


name: (3R)-3-hydroxydodecanoyl-CoA + NADP(+) => 3-oxododecanoyl-CoA + H(+) + NADPH


name: H(+) + nonanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-nonenoyl-CoA + reduced [electron-transfer flavoprotein]


name: PRMT5 methylates TP53 (Rattus norvegicus)


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: a 16-oxosteroid + H(+) + NADH => a 16alpha-hydroxysteroid + NAD(+)


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Dictyostelium discoideum)


name: Disassociation and translocation of STATs to the nucleus (Bos taurus)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Sus scrofa)


name: ligand-activated transcription activator activity


name: Dephosphorylation of p107 (RBL1) by PP2A (Rattus norvegicus)


name: dalnigrein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O => beta-D-apiofuranosyl-(1->6)-D-glucopyranose + dalnigrein + H(+)


name: RAC3 GEFs activate RAC3 (Xenopus tropicalis)


name: 4,4'-diaponeurosporenoate + 2 H(+) + NADH => 4,4'-diaponeurosporenal + H2O + NAD(+)


name: CDK5:p25 phosphorylates lamin A (Homo sapiens)


name: (3R)-hydroxyhexanoyl-CoA <=> (2E)-hexenoyl-CoA + H2O


name: LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Rattus norvegicus)


name: 1-O-hexadecyl-2-amino-sn-glycerol + ATP = 1-O-hexadecyl-2-desoxy-2-amino-sn-glycero-3-phosphate + ADP + H(+)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Rattus norvegicus)


name: L-ornithine + succinyl-CoA => CoA + H(+) + N(2)-succinyl-L-ornithine


name: ERK1/2/5 activate RSK1/2/3 (Gallus gallus)


name: adenosine(2142) in 25S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyladenosine(2142) in 25S rRNA + S-adenosyl-L-homocysteine


name: 2-hydroxy-3-methylhexadecanoyl-CoA <=> 2-methylpentadecanal + formyl-CoA


name: 4-aminobutanal + AH2 + propane-1,3-diamine => A + H2O + spermidine


name: a 2-acylphloroglucinol + dimethylallyl diphosphate <=> a 2-acyl-4-prenylphloroglucinol + diphosphate


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a (Mus musculus)


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Sus scrofa)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Schizosaccharomyces pombe)


name: DCN binds collagen I, II, III, VI fibrils (Gallus gallus)


name: PSMD14 cleaves K63-linked ubiquitin (Danio rerio)


name: 1,3-dinitrobenzene + NADH + O2 = 4-nitrocatechol + H(+) + NAD(+) + nitrite


name: LTC4 is exported from the cytosol by ABCC1 (Sus scrofa)


name: Addition of nucleotides leads to transcript elongation (Mus musculus)


name: CASP8 cleaves N4BP1 at D424, D490 (Canis familiaris)


name: H2O + oxaloacetate + propanoyl-CoA => 2-methylcitrate + CoA + H(+)


name: Association of procollagen type I (Canis familiaris)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Canis familiaris)


name: a ganglioside GP1c (d18:1(4E)) + H2O <=> a ganglioside GQ1c (d18:1(4E)) + N-acetylneuraminate


name: factor IXa associates with cell membrane (Canis familiaris)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Caenorhabditis elegans)


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Mus musculus)


name: 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + nonanedioate


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Mus musculus)


name: NFE2L2-dependent HMOX1 gene expression (Homo sapiens)


name: mitomycin A + S-adenosyl-L-homocysteine => 6-demethylmitomycin A + S-adenosyl-L-methionine


name: H2O + P(1),P(6)-bis(5'-adenosyl) hexaphosphate => adenosine 5'-tetraphosphate + ADP + 2 H(+)


name: butan-2-one + hydrogen cyanide = 2-hydroxy-2-methylbutanenitrile


name: PP5 dephosphorylates RAF1 S338 (Plasmodium falciparum)


name: a globoside Gb3Cer (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + D-galactose


name: H2O + N-sulfo-D-glucosamine <=> D-glucosamine + sulfate


name: B4GALTs transfer Gal to a branch of keratan (Danio rerio)


name: (2E)-dodecenedioyl-CoA + AH2 => A + dodecanedioyl-CoA


name: Synthesis of GABA by GAD2 (Homo sapiens)


name: Activation of Protein Kinase C novel isoforms (Drosophila melanogaster)


name: IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Gallus gallus)


name: 4,5beta-dihydrocortisone + NADP(+) => cortisone + H(+) + NADPH


name: Translocation of PDK1 to Plasma membrane (Saccharomyces cerevisiae)


name: PC is converted to PS by PTDSS1 (Plasmodium falciparum)


name: PAK1 or PAK2 phosphorylates MYLK (Bos taurus)


name: NIK autophosphorylates on T559 (Sus scrofa)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Saccharomyces cerevisiae)


name: PLK1 phosphorylates NUDC (Rattus norvegicus)


name: asperaculane D + O2 + reduced [NADPH--hemoprotein reductase] => asperaculane E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NEMO subunit of IKK complex binds to activated IRAK1 (Sus scrofa)


name: SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol (Homo sapiens)


name: 2-hydroxycyclohexan-1-one + H(+) + NADH => NAD(+) + trans-cyclohexane-1,2-diol


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Danio rerio)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Caenorhabditis elegans)


name: an acyl-CoA + H(+) + malonyl-CoA => a 3-oxoacyl-CoA + CO2 + CoA


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA


name: (E)-isoeugenol + O2 => acetaldehyde + vanillin


name: chenodeoxycholate + UDP-alpha-D-glucuronate => chenodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Homo sapiens)


name: Autophosphorylation of BTK/ITK (Xenopus tropicalis)


name: doxorubicin(in) + H(+)(out) <=> doxorubicin(out) + H(+)(in)


name: (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + holo-[ACP] => (9Z)-hexadecenoyl-[ACP] + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)


name: dibenzothiophene 5-oxide + FMN + H(+) + H2O => dibenzothiophene + FMNH2 + O2


name: L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H(+) + UDP


name: 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O = (9Z,12Z)-octadecadienoate + glycerol + H(+)


name: S-adenosyl-L-methionine + sterigmatocystin => 8-O-methylsterigmatocystin + H(+) + S-adenosyl-L-homocysteine


name: H2O + substance P = L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-7)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Canis familiaris)


name: CCND1 recruits HDAC4 to RUNX3 (Rattus norvegicus)


name: H(+) + H2O + N-terminal L-asparaginyl-[protein] => N-terminal L-aspartyl-[protein] + NH4(+)


name: 2-oxoglutarate + gibberellin A9 + O2 <=> CO2 + gibberellin A4 + succinate


name: 2-(N(omega)-L-arginino)succinate => fumarate + L-arginine


name: 2 H(+) + N-(carboxyaminomethyl)urea = CO2 + N-(aminomethyl)urea


name: L-aspartate + NH4(+) => H2O + L-asparagine


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Xenopus tropicalis)


name: (13Z)-docosenoyl-CoA + sphinganine <=> CoA + H(+) + N-(13Z-docosenoyl)-sphinganine


name: ZnT1 mediates the efflux of zinc from the cell (Schizosaccharomyces pombe)


name: 2'-hydroxy-2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2',2'-dihydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 3'-phosphoadenylyl sulfate + glycodeoxycholate <=> 3alpha-sulfoglycodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: 3-oxocyclopentanecarbonitrile + 2 H2O <=> 3-oxocyclopentanecarboxylate + NH4(+)


name: 11-oxomiltiradiene + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + veratrole <=> 3-methoxyphenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Caenorhabditis elegans)


name: Formation of the Flap Intermediate (Saccharomyces cerevisiae)


name: (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2 <=> (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H(+) + H2O


name: 3 Na(+)(out) + selenate(out) => 3 Na(+)(in) + selenate(in)


name: GOT2 transaminates OA and L-Glu (Dictyostelium discoideum)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Drosophila melanogaster)


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Canis familiaris)


name: 2 hydrogencarbonate(out) + Mn(2+)(out) => 2 hydrogencarbonate(in) + Mn(2+)(in)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)


name: 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) => 1-octadecanoyl-2-(15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Sus scrofa)


name: HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH (Homo sapiens)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Rattus norvegicus)


name: glycine betaine + H(+) + S-adenosyl-L-homocysteine => N,N-dimethylglycine + S-adenosyl-L-methionine


name: CO2 + formate + methylamine + succinate semialdehyde => (E)-2-((N-methylformamido) methylene)succinate + H(+) + 2 H2O


name: (6E)-8-oxogeranial + H(+) + NADPH => (R)-8-oxocitronellyl enol + NADP(+)


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Drosophila melanogaster)


name: Interaction of DAP12 and KIR2DS5 (Homo sapiens)


name: PGAM5 dodecamer dephosphorylates p-S336-ME1 (Danio rerio)


name: cyclic dehypoxanthinylfutalosinate = 1,4-dihydroxy-6-naphthoate + dihydroxyacetone


name: 1-O-(trans-sinapoyl)-beta-D-glucose + anthocyanin A8 => anthocyanin A11 + D-glucose


name: Potassium voltage-gated channels close in reponse to PKA (Caenorhabditis elegans)


name: Expression of CXCR4 in definitive endoderm (Homo sapiens)


name: H2O + N(6)-(2E)-butenoyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: 1D-myo-inositol 5-phosphate + H2O => myo-inositol + phosphate


name: MFSD2A transports LPC from extracellular region to plasma membrane (Mus musculus)


name: apo-[BtrI ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[BtrI ACP]


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Xenopus tropicalis)


name: alpha-D-glucosamine 6-phosphate + H2O => beta-D-fructose 6-phosphate + NH4(+)


name: an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] => a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: SOX17 and TFAP2C bind the CBFA2T2 gene (Homo sapiens)


name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA (Mus musculus)


name: WNT ligands traffic to the plasma membrane (Canis familiaris)


name: formyl-CoA + heptadecanal => (2R)-2-hydroxyoctadecanoyl-CoA


name: L-phenylalanine(out) + L-tryptophan(in) = L-phenylalanine(in) + L-tryptophan(out)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine <=> a 1,2-diacyl-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine


name: 2 (S)-lactate(in) + prostaglandin H2(out) <=> 2 (S)-lactate(out) + prostaglandin H2(in)


name: L-phenylalanine(in) + Na(+)(in) => L-phenylalanine(out) + Na(+)(out)


name: IL21 receptor STAT phosphorylation (Sus scrofa)


name: BTN2A2 binds T cell surface (Mus musculus)


name: PDCL releases folded G-beta from TRiC/CCT (Bos taurus)


name: DHODH:FMN oxidises (S)-DHO to orotate (Rattus norvegicus)


name: PREDN,PREDL diffuse into hepatic cells (Homo sapiens)


name: IGF1R phosphorylates SHC1 (Canis familiaris)


name: H(+) + NAD(+) + reduced [4Fe-4S]/[3Fe-4S]-[ferredoxin] <=> NADH + oxidized [4Fe-4S]/[3Fe-4S]-[ferredoxin]


name: (R)-2-hydroxyglutarate + FAD + H(+) = 2-oxoglutarate + FADH2


name: H2O + N(6)-hexanoyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-hexanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: a ribonucleotidyl-ribonucleotide-RNA <=> a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA


name: dADP(out) + H(+)(out) + phosphate(in) => dADP(in) + H(+)(in) + phosphate(out)


name: 2 3-(4-hydroxyphenyl)pyruvate <=> aspulvinone E + H2O


name: SGSH hydrolyses Heparan sulfate chain(2) (Drosophila melanogaster)


name: ATP(in) + CoA(in) + H(+)(out) + tetracosanoate(out) => AMP(in) + diphosphate(in) + H(+)(in) + tetracosanoyl-CoA(in)


name: Disassociation of CLIP from MHC II (Mus musculus)


name: adenylyl-sulfate reductase (glutathione) activity


name: MAPK1-dependent phosphorylation of MITF-M (Homo sapiens)


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Canis familiaris)


name: BLT receptors can bind LTB4 (Xenopus tropicalis)


name: 2-hydroxyisobutanoyl-CoA + L-lysyl-[protein] <=> CoA + H(+) + N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein]


name: 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Schizosaccharomyces pombe)


name: CK2 phosphorylates PDCL (Drosophila melanogaster)


name: 4-methylumbelliferone beta-D-glucuronate(in) + ATP + H2O <=> 4-methylumbelliferone beta-D-glucuronate(out) + ADP + H(+) + phosphate


name: glyoxylate + N(omega)-methyl-L-arginine => 5-(3-methylguanidino)-2-oxopentanoate + glycine


name: a 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine-DNA + H2O => a 3'-end 2'-deoxyribonucleotide 3'-phosphate-DNA + GMP + 2 H(+)


name: 3-oxo-(5Z)-dodecenoyl-[ACP] + CO2 + holo-[ACP] => (3Z)-decenoyl-[ACP] + H(+) + malonyl-[ACP]


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Sus scrofa)


name: VTN binds collagens II, III and V (Mus musculus)


name: H(+) + N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine => L-arginyl-[protein] + S-adenosyl-L-methionine


name: 2'-deoxyguanosine + NAD(+) => H(+) + N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine + nicotinamide


name: GBF1 stimulates nucleotide exchange on ARF4 (Rattus norvegicus)


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Canis familiaris)


name: 2-oxoglutarate + an N(3)-methylcytidine in mRNA + O2 <=> a cytidine in mRNA + CO2 + formaldehyde + succinate


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Saccharomyces cerevisiae)


name: an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Duplex siRNA is loaded into Argonaute (Bos taurus)


name: NEIL2 cleaves 5-OHU from damaged DNA (Gallus gallus)


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: dodecanoyl-CoA + glycine = CoA + H(+) + N-dodecanoylglycine


name: AKR1C3 reduces atRAL to atROL (Sus scrofa)


name: (3S)-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O


name: (2E)-geranyl diphosphate + olivetolate => cannabigerolate + diphosphate


name: IDS hydrolyses Heparan sulfate chain(5) (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: AGO1,2:small RNA complexes interact with chromatin (Xenopus tropicalis)


name: SLC7A3 (CAT-3)-mediated uptake of cationic amino acids (Mus musculus)


name: cocaine + H2O = benzoate + ecgonine methyl ester + H(+)


name: Membrane localised SGG phosphorylates ARR (Drosophila melanogaster)


name: type 8 metabotropic glutamate receptor binding


name: ATP12A:ATP4B exchanges K+ for H+ (Canis familiaris)


name: PHF8 demethylates MeK21-histone H4 (Bos taurus)


name: E2F6:TFDP1 binds to MGA:MAX (Sus scrofa)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Bos taurus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA


name: 3-methyleneoxindole + H(+) + NADPH => 3-methyloxindole + NADP(+)


name: Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Xenopus tropicalis)


name: dimethylallyl diphosphate + preechinulin = diphosphate + tardioxopiperazine B


name: acetylsalicylate + L-lysyl-[protein] => H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(in) + ATP + H2O = 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(out) + ADP + H(+) + phosphate


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Homo sapiens)


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA = (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H2O


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-Glc + GDP + H(+) => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose


name: NEIL1,NEIL2 recruits POLB to incised AP site (Xenopus tropicalis)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Homo sapiens)


name: ATP + ergothioneine(out) + H2O => ADP + ergothioneine(in) + H(+) + phosphate


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Gallus gallus)


name: calarene + diphosphate => (2E,6E)-farnesyl diphosphate


name: cis-muurola-3,5-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Release of Cytochrome c from mitochondria (Bos taurus)


name: EDNRA, EDNRB bind non-selective ERAs (Rattus norvegicus)


name: S-adenosyl-L-methionine + uridine(54) in tRNA = 5-methyluridine(54) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: TRIF:activated TLR3/TLR4 complex recruits RIP1 (Canis familiaris)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Caenorhabditis elegans)


name: ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine => (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine


name: acetate + beta-alanine => H2O + N-acetyl-beta-alanine


name: (E)-4-hydroxynon-2-enal + H2O + O2 = (E)-4-hydroxynon-2-enoate + H(+) + H2O2


name: PDGF-BB clevage by Furin (Caenorhabditis elegans)


name: D-allose + L-lysyl-[protein] => H2O + N(6)-(D-psicosyl)-L-lysyl-[protein]


name: SMPD1 hydrolyzes SPHM (Xenopus tropicalis)


name: 2-oxoglutarate + 5-aminopentanoate <=> 5-oxopentanoate + L-glutamate


name: 1,2-didecanoyl-sn-glycerol + ATP = 1,2-didecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: C5a receptor binds C5a anaphylatoxin (Bos taurus)


name: 2-oxoglutarate + decanoyl-CoA + O2 => 2-hydroxydecanoyl-CoA + CO2 + succinate


name: (6E,10E)-geranyllinalool + O2 + reduced [NADPH--hemoprotein reductase] => (3E,7E)-4,8,12-trimethyltrideca 1,3,7,11-tetraene + but-3-en-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1,2-diacylglycerol + H2O <=> a 2-acylglycerol + a fatty acid + H(+)


name: 1-O-alkyl-sn-glycero-3-phosphocholine + an acyl-CoA <=> 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA


name: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + GDP-alpha-D-mannose = (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + GDP + H(+)


name: MAF1 translocates to the nucleus (Mus musculus)


name: Association of Golgi  transport vesicles with microtubules (Homo sapiens)


name: oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor


name: "With a quinone or similar compound as acceptor"


name: YME1L1 proteolyzes unassembled proSMDT1 (Rattus norvegicus)


name: MTTP binds lomitapide (Drosophila melanogaster)


name: ALDH3A2-2 oxidizes pristanal to pristanate (Mus musculus)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: (2E)-hexadecenoyl-[ACP] + H(+) + NADPH = hexadecanoyl-[ACP] + NADP(+)


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)


name: 2 flaviolin + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3,8'-biflaviolin + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Prokineticin receptors bind prokineticin (Rattus norvegicus)


name: GEFs activate RhoA,B,C (Schizosaccharomyces pombe)


name: (R)-glycerate + CO2 + NAD(+) <=> 2-hydroxy-3-oxosuccinate + 2 H(+) + NADH


name: a long-chain fatty acid + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> a long-chain fatty acyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: [aequorin]--dioxetanone => [excited state blue fluorescent protein] + CO2


name: 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a menaquinol + dihydroxyacetone phosphate => a menaquinone + sn-glycerol 3-phosphate


name: gibberellin A15 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => gibberellin A24 + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: CYP2C19 5-hydroxylates omeprazole (Rattus norvegicus)


name: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: dUTP + H2O => dUMP + pyrophosphate (Schizosaccharomyces pombe)


name: ent-cassa-12,15-dien-2-one + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N-acetyl-D-muramoyl-L-alanine <=> L-alanine + N-acetyl-D-muramate


name: A4GALT transfers galactose to LacCer (Drosophila melanogaster)


name: GDP-alpha-D-mannose + H2O => alpha-D-mannose 1-phosphate + GMP + 2 H(+)


name: 2',3,4,4',6'-pentahydroxychalcone + UDP-alpha-D-glucose <=> 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H(+) + UDP


name: HDHD1:Mg2+ dephosphorylates PURIDP (Saccharomyces cerevisiae)


name: ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Mus musculus)


name: SOS mediated nucleotide exchange of RAS (SHC) (Homo sapiens)


name: N-(6-aminohexanoyl)-6-aminohexanoate => 1,8-diazacyclotetradecane-2,9-dione + H2O


name: 2 H2O + 2 L-dopaquinone => 2 L-dopa + O2


name: 15-cis-4,4'-diapophytoene + 3 FAD + 3 H(+) => all-trans-4,4'-diaponeurosporene + 3 FADH2


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Homo sapiens)


name: activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin (Rattus norvegicus)


name: Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Bos taurus)


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Canis familiaris)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Homo sapiens)


name: PRLR binds SCF beta-TrCP complex (Mus musculus)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Rattus norvegicus)


name: 2,4,5-trichlorocyclohexa-2,5-dien-1-ol + H2O => 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + chloride + H(+)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Caenorhabditis elegans)


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Canis familiaris)


name: carnosine + S-adenosyl-L-methionine = anserine + H(+) + S-adenosyl-L-homocysteine


name: (E)-4-coumarate + UDP-alpha-D-glucose = 1-O-(trans-4-coumaroyl)-beta-D-glucose + UDP


name: GLRA:GLRB:Gly transports extracellular Cl- to cytosol (Sus scrofa)


name: ADP + D-glucosamine 6-phosphate + H(+) => ATP + D-glucosamine


name: 3-dehydroquinate + H(+) + NADH => L-quinate + NAD(+)


name: methyl thiocyanate + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + thiocyanate


name: 2 ATP <=> 3',3'-c-di-AMP + 2 diphosphate


name: (2S)-2-isopropylmalate + CoA + H(+) => 3-methyl-2-oxobutanoate + acetyl-CoA + H2O


name: Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 (Danio rerio)


name: H2O + orobanchol <=> 5-hydroxy-3-methylfuran-2(5H)-one + orobanchol ABC-rings


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 => 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z)-docosapentaenoate


name: Translocation of NFATC1:CaN:CaM to nucleus (Bos taurus)


name: a 3-oxoacyl-[ACP] + CO2 + holo-[ACP] => a fatty acyl-[ACP] + H(+) + malonyl-[ACP]


name: (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NADP(+) <=> 4-methylcatechol + CO2 + NADPH


name: ATP + N-(D-ribulosyl)-cadaverine <=> ADP + H(+) + N-(3-O-phospho-D-ribulosyl)-cadaverine


name: (9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (1S,4R)-isodihydrocarvone + H(+) + NADPH + O2 = (3S,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: phenylethanolamine + S-adenosyl-L-methionine = H(+) + N-methylphenylethanolamine + S-adenosyl-L-homocysteine


name: loganin + S-adenosyl-L-homocysteine => loganate + S-adenosyl-L-methionine


name: D-histidine(out) + H(+)(out) + L-ornithine(in) => D-histidine(in) + H(+)(in) + L-ornithine(out)


name: MAPK4,6 translocate to the cytoplasm (Caenorhabditis elegans)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Homo sapiens)


name: PRLR binds SCF beta-TrCP complex (Gallus gallus)


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Sus scrofa)


name: glycine betaine(in) + Na(+)(in) => glycine betaine(out) + Na(+)(out)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Xenopus tropicalis)


name: 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O


name: [thioredoxin]-dithiol + tert-butyl hydroperoxide = [thioredoxin]-disulfide + H2O + tert-butanol


name: glutathione(out) + 3 Na(+)(out) => glutathione(in) + 3 Na(+)(in)


name: proton transmembrane transporter activity


name: Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: miRNA inhibitor activity via base-pairing


name: Dissociation of  transcript with 5'-GMP from GT (Schizosaccharomyces pombe)


name: benzaldehyde + FMN + H(+) + H2O + N-acetyl-S-hydroxy-L-cysteine => (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMNH2 + O2


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Canis familiaris)


name: Endonucleolytic RISC hydrolyzes target RNAs (Homo sapiens)


name: Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Canis familiaris)


name: 4-aminobutanoate(out) + chloride(out) + 2 Na(+)(out) <=> 4-aminobutanoate(in) + chloride(in) + 2 Na(+)(in)


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Bos taurus)


name: chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] => 3,8-divinyl chlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: carbamoyl adenylate + diphosphate + phosphate => ATP + carbamoyl phosphate + H2O


name: chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) (Sus scrofa)


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Mus musculus)


name: Aquaporin-1 passively transports water out of cell (Mus musculus)


name: GOT2 transaminates OA and L-Glu (Schizosaccharomyces pombe)


name: 2-oxoglutarate + L-2-aminohexanoate => 2-oxohexanoate + L-glutamate


name: Activated CIT binds KIF14 and PRC1 (Rattus norvegicus)


name: (S)-1-pyrroline-5-carboxylate + H(+) + H2O => L-glutamate 5-semialdehyde


name: apigenin + S-adenosyl-L-methionine => acacetin + H(+) + S-adenosyl-L-homocysteine


name: SYS1 binds AcM-ARFRP1 (Drosophila melanogaster)


name: 2 H(+) + NADH + neurosporaxanthin => 4'-apo-beta-carotenal + H2O + NAD(+)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: NPC2 transfers CHOL to NPC1 (Rattus norvegicus)


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Sus scrofa)


name: H2O + nicotinamide => NH4(+) + nicotinate


name: Neuroglobin:oxygen dissociates (Gallus gallus)


name: Autophosphorylation of PAK1,2,3 (Sus scrofa)


name: 2-(9Z,12Z-octadecadienoyl)-glycerol + H2O => (9Z,12Z)-octadecadienoate + glycerol + H(+)


name: Activated TP receptor binds G-protein  G13 (Canis familiaris)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] => 1,6-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Saccharomyces cerevisiae)


name: SRPK1 phosphorylates PRM2 in PRM2:dsDNA (Homo sapiens)


name: 3'-phosphoadenylyl sulfate(in) + adenosine 3',5'-bisphosphate(out) => 3'-phosphoadenylyl sulfate(out) + adenosine 3',5'-bisphosphate(in)


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Mus musculus)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + sn-glycerol 3-phosphocholine <=> (9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Rattus norvegicus)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)


name: biphenyl-2-ol + H(+) + NADH + O2 <=> biphenyl-2,3-diol + H2O + NAD(+)


name: Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Homo sapiens)


name: 2-dehydropantoate => 3-methyl-2-oxobutanoate + formaldehyde


name: methyl-Co(III)-[tetramethylammonium-specific corrinoid protein] + trimethylamine => Co(I)-[tetramethylammonium-specific corrinoid protein] + H(+) + tetramethylammonium


name: glyoxylate + L-leucine <=> 4-methyl-2-oxopentanoate + glycine


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Caenorhabditis elegans)


name: Arachidonic acid  is converted to 12-oxoETE by ALOX12 (Danio rerio)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Rattus norvegicus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Homo sapiens)


name: 3-guanidinopropanoate + L-ornithine => beta-alanine + L-arginine


name: PIAS2,3,4 SUMOylate RORA with SUMO2 (Gallus gallus)


name: SUCLG1/G2 cleaves succinyl-CoA (Rattus norvegicus)


name: 2-aminocyclohexanol + H2O + NAD(+) => 2-hydroxycyclohexan-1-one + H(+) + NADH + NH4(+)


name: Translocation of activated BAD protein to mitochondria (Danio rerio)


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: L-Glutamine transport into neurons (Danio rerio)


name: D-galactose 6-phosphate + NADP(+) <=> 6-phospho-D-galactono-1,5-lactone + H(+) + NADPH


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acylsphing-4-enine => a 1,2-diacyl-sn-glycerol + an N-acylsphing-4-enine-(1D-myo-inositol)


name: Defective ALG9 does not add the last mannose to the N-glycan precursor (Homo sapiens)


name: H(+) + NADH + O2 + pyrrole-2-carboxylate => 5-hydroxypyrrole-2-carboxylate + H2O + NAD(+)


name: MIA3 binds procollagen VII (Homo sapiens)


name: H2O + 2 monodehydro-L-ascorbate radical + N-decanoyl-(2S)-hydroxyglycine => 2 L-ascorbate + N-decanoylglycine + O2


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Sus scrofa)


name: PTPN11 dephosphorylates RUNX1 (Bos taurus)


name: carcinine transmembrane transporter activity


name: PKC-delta is activated (Saccharomyces cerevisiae)


name: Formation of active mTORC1 complex (Xenopus tropicalis)


name: 32-oxoeburicol + O2 + reduced [NADPH--hemoprotein reductase] => 14-demethyleburicol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: DLD dimer dehydrogenates dihydrolipoyl (Sus scrofa)


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Saccharomyces cerevisiae)


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Bos taurus)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Caenorhabditis elegans)


name: NSF ATPase activity dissociates cis-SNARE (Schizosaccharomyces pombe)


name: SGSH hydrolyses Heparan sulfate chain(7) (Mus musculus)


name: TFAM binds to mitochondrial promoters (Drosophila melanogaster)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Xenopus tropicalis)


name: Autocatalytic activation of proMMP2 (Xenopus tropicalis)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Bos taurus)


name: RDH5 oxidises 11cROL to 11cRAL (Gallus gallus)


name: Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity (Homo sapiens)


name: p-6Y-VEGFR2 binds FYN (Canis familiaris)


name: Glucagon-like Peptide 1 is secreted from intestinal L cells (Rattus norvegicus)


name: MCM8 binds CDC6 (Drosophila melanogaster)


name: Recruitment of VAV to p-SLP-76 (Drosophila melanogaster)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate <=> (S)-3-methyl-2-oxopentanoate + H2O


name: (6E)-8-methylnon-6-enoyl-CoA + 4-hydroxy-3-methoxy-benzenemethanol <=> capsiate + CoA


name: (3R)-[(10S)-11-epoxyfarnesyl]-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate + H(+) => asnovolin H


name: RDH13 reduces atRAL to atROL (Bos taurus)


name: XPC binds RAD23 and CETN2 (Gallus gallus)


name: trans-Golgi Network Lysosomal Vesicle Scission (Sus scrofa)


name: (4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]


name: campestanol + O2 + reduced [NADPH--hemoprotein reductase] = 6-deoxycathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activation of EPACs by cAMP (Caenorhabditis elegans)


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Homo sapiens)


name: RRAGA,B hydrolyzes GTP (Xenopus tropicalis)


name: ATP + H(+) + hexadecanoate <=> diphosphate + hexadecanoyl-AMP


name: a (2R)-2-hydroxycarboxylate + NAD(+) = a 2-oxocarboxylate + H(+) + NADH


name: ATP + hydrogencarbonate <=> ADP + carboxyphosphate


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Homo sapiens)


name: IL12A:IL12B translocates from late endosome lumen to extracellular region (Gallus gallus)


name: Hypochlorous acid (HOCL) oxidizes Cys residues to form Cys-sulfenyl chloride (Homo sapiens)


name: 13-cis-retinal + H2O + NAD(+) <=> 13-cis-retinoate + 2 H(+) + NADH


name: PYGO binds to the LGS:ARM complex (Drosophila melanogaster)


name: PHF8 demethylates histone H4K20me1 (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate => diphosphate + germacrene D


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O => (9Z,12Z)-octadecadienoate + 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+)


name: L-fucose(out) + 2 Na(+)(out) <=> L-fucose(in) + 2 Na(+)(in)


name: a III(4)-a-Fuc-Lc4Cer(d18:1(4E)) + GDP-beta-L-fucose <=> a lactoside IV(2),III(4)-a-[Fuc]2-Lc4Cer(d18:1(4E)) + GDP + H(+)


name: dehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) => dehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Saccharomyces cerevisiae)


name: citral + H2O + O2 = 3,7-dimethylocta-2,6-dienoate + H(+) + H2O2


name: ABL1 phosphorylates RAD52 (Mus musculus)


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Sus scrofa)


name: Expression of PLAC8 in the nephric duct (Homo sapiens)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+) => 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O


name: trans-Golgi Network Coat Activation (Rattus norvegicus)


name: MKRN1 polyubiquitinates PTEN (Dictyostelium discoideum)


name: Translocation of Vav1 to CD28 (Rattus norvegicus)


name: 25(R) TetraHCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate


name: ALDH1A1 oxidises GA to DGA (Homo sapiens)


name: AMP + H2O + Mo-molybdopterin => adenylyl-molybdopterin + H(+) + molybdate


name: YWHAE dimer binds phosphorylated DENND1 proteins (Homo sapiens)


name: a hydroxy polyunsaturated fatty acid + H2O + NADP(+) => a hydroperoxy polyunsaturated fatty acid + H(+) + NADPH


name: FGAM + ATP => AIR + ADP + Pi (Sus scrofa)


name: The Immunoglobulin of the BCR binds antigen (Canis familiaris)


name: SENP1,2,5 proteolytically process SUMO3 (Bos taurus)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Drosophila melanogaster)


name: RNA polymerase II CTD heptapeptide repeat kinase activity


name: androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] <=> 6beta-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: USP10 deubiquitinates SNX3, CFTR (Saccharomyces cerevisiae)


name: CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + L-serine <=> archaetidylserine + CMP + H(+)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O => 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + H(+) + hexadecanoate


name: hyocholate + UDP-alpha-D-glucuronate => H(+) + hyocholate 6-O-(beta-D-glucuronate) + UDP


name: Formation of Pol zeta complex (Dictyostelium discoideum)


name: calciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = calcidiol + H2O + 2 oxidized [adrenodoxin]


name: PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA (Homo sapiens)


name: Association of procollagen type VIII (Bos taurus)