name: 2 7-demethylsiderin + NADPH + O2 = desertorin A + 2 H2O + NADP(+)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc + GDP + H(+) => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-D-GlcNAc + GDP-beta-L-fucose


name: (1'S,5'S)-averufin + H2O => (S)-5'-oxoaverantin + H(+)


name: MTORC1 dissociates from ULK complex (Canis familiaris)


name: H(+) + rebeccamycin + S-adenosyl-L-homocysteine => 4'-demethylrebeccamycin + S-adenosyl-L-methionine


name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Homo sapiens)


name: KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Canis familiaris)


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-dodecanoylglycerol <=> 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: (2E,6E)-farnesyl diphosphate <=> (+)-germacrene D + diphosphate


name: Co(I)-[dimethylamine-specific corrinoid protein] + dimethylamine + H(+) <=> methyl-Co(III)-[dimethylamine-specific corrinoid protein] + methylamine


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Bos taurus)


name: H(+)(in) + L-citrulline(in) + L-ornithine(out) = H(+)(out) + L-citrulline(out) + L-ornithine(in)


name: 4-(phosphooxy)-L-threonine + NAD(+) <=> 3-amino-2-oxopropyl phosphate + CO2 + NADH


name: COX18 inserts nascent MT-CO2 in COX20:TMEM77 (Mus musculus)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Bos taurus)


name: a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP(+) = a 4alpha-methyl-3-oxosteroid + CO2 + NADPH


name: proatranorin III + S-adenosyl-L-methionine <=> atranorin + S-adenosyl-L-homocysteine


name: TNKS and TNKS2 PARylate PTEN (Gallus gallus)


name: H2O + L-asparaginyl-[protein] <=> L-aspartyl-[protein] + NH4(+)


name: G-beta:G-gamma inhibits Adenylate cyclase (Mus musculus)


name: 2'-deoxycytidine(in) + H(+)(in) = 2'-deoxycytidine(out) + H(+)(out)


name: dUMP + H2O => 2'-deoxyuridine + phosphate


name: a ribonucleotidyl-ribonucleotide-RNA => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA


name: (3S)-hydroxydecanoyl-CoA + NAD(+) => 3-oxodecanoyl-CoA + H(+) + NADH


name: (S)-1-aminoethylphosphonate + acetyl-CoA <=> [(1S)-1-acetamidoethyl]phosphonate + CoA


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Danio rerio)


name: NF1 is degraded by the proteasome (Sus scrofa)


name: a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside + H(+) + UDP => a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-alpha-D-glucose


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Release of SEPT4 from mitochondria (Schizosaccharomyces pombe)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: ACSF3 ligates CoA-SH to VLCFA (Homo sapiens)


name: IL20 binds IL20RA:JAK1:IL20RB (Mus musculus)


name: RBP3 regulates atROL taken up by Muller cells (Bos taurus)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Sus scrofa)


name: H2O + hexadecanoyl-[ACP] <=> H(+) + hexadecanoate + holo-[ACP]


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Rattus norvegicus)


name: 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADH => (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NAD(+)


name: Phospho-CREB1 binds the promoter of the CEBPB gene (Homo sapiens)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3] + succinate


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a cytidine in tRNA + S-adenosyl-L-methionine <=> an N(3)-methylcytidine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H(+) + NADPH


name: Initiation of SAHF formation (Canis familiaris)


name: (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NAD(+) => 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADH


name: Autocatalytic activation of proMMP2 (Rattus norvegicus)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Bos taurus)


name: p-S857 NCOA3 binds ETV4 (Drosophila melanogaster)


name: cordypyrone A + O2 + reduced [NADPH--hemoprotein reductase] = cordypyrone B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cholesterol + UDP-alpha-D-galactose <=> cholesteryl 3-beta-D-galactoside + H(+) + UDP


name: (2E)-13-methyltetradecenal + phosphoethanolamine => 15-methylhexadecasphing-4-enine 1-phosphate


name: 2 H(+) + 2 H2O + methylenediurea => CO2 + N-(hydroxymethyl)urea + 2 NH4(+)


name: glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Homo sapiens)


name: SRD5A1 dehydrogenates TEST to DHTEST (Sus scrofa)


name: an L-N,N-dihydroxypolyhomomethionine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => an L-N-hydroxypolyhomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Canis familiaris)


name: PIAS2-2 SUMOylates SUZ12 with SUMO1 (Schizosaccharomyces pombe)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = 8-hydroxycopalyl diphosphate


name: H2 + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + sn-glycerol 3-phosphocholine => (9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: 3-deoxy-D-glycero-2,5-hexodiulosonate + H(+) + NADH => 2-dehydro-3-deoxy-D-gluconate + NAD(+)


name: an alpha-L-rhamnosyl-(1->4)-beta-D-glucuronide = a 4-deoxy-alpha-L-threo-hex-4-enopyranuronoside + L-rhamnopyranose


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine = (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: 3-methylbutanol + acetate + H(+) => 3-methylbutyl acetate + H2O


name: Na(+)(out) + xanthine(out) <=> Na(+)(in) + xanthine(in)


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Canis familiaris)


name: pre-VLDL binds lipids to form VLDL (Gallus gallus)


name: p-S54,92,203-BRF1 binds 14-3-3 (Danio rerio)


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Xenopus tropicalis)


name: a quaternary ammonium(out) + ATP + H2O <=> a quaternary ammonium(in) + ADP + H(+) + phosphate


name: p-T182 MAPKAPK5 binds DNAJB1 (Bos taurus)


name: Constitutive phosphorylation  by pERK1/2 (Drosophila melanogaster)


name: Phosphopantetheine conjugation of the ACP domain of FAS (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + xanthotoxin => 5-hydroxyxanthotoxin + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CDC42 and PIP2 bind WASL, activating it (Sus scrofa)


name: 2-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + salicylate


name: a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+) + L-tyrosine => a 5'-end L-tyrosylphosphate-2'-deoxynucleoside-DNA + H2O


name: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = D-glucose + indole-3-acetyl-1D-myo-inositol


name: α1-agonists bind ADRA1A,B,D (Danio rerio)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 9-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2S)-2-amino-2'-deoxyadenylo-succinate = dZMP + fumarate


name: 3-oxochola-4,17-dien-22-oyl-CoA + H2O => 17-hydroxy-3-oxochol-4-en-22-oyl-CoA


name: Heparin binds PKR (Caenorhabditis elegans)


name: CBL ubiquitinates FRS2 and FGFR1 (Gallus gallus)


name: MDM2 gene expression is repressed by NPAS4 (Homo sapiens)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Drosophila melanogaster)


name: lithocholate + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + hyodeoxycholate + oxidized [NADPH--hemoprotein reductase]


name: Association of procollagen type XVIII (Mus musculus)


name: glutarate + 2 H(+) + NADPH => 5-oxopentanoate + H2O + NADP(+)


name: an acyl-CoA + sn-glycerol 3-phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine + CoA


name: 2 (R)-3-hydroxybutanoate + H(+) => (3R)-hydroxybutanoate dimer + H2O


name: a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid + 8 oxidized 2[4Fe-4S]-[ferredoxin] = a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Xenopus tropicalis)


name: L-phenylalanine + tetrahydro-4-hydroxyphenylpyruvate <=> 3-phenylpyruvate + tetrahydrotyrosine


name: SCD5 desaturates ST-CoA to OLE-CoA (Dictyostelium discoideum)


name: IL3 stimulation induces Vav binding to Tec kinase (Rattus norvegicus)


name: H2O + O-phospho-L-homoserine => L-threonine + phosphate


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Sus scrofa)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Mus musculus)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate => phenylacetonitrile + sulfate + sulfur


name: acetyl-CoA + D-tryptophan <=> CoA + H(+) + N-acetyl-D-tryptophan


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Mus musculus)


name: a phenolic steroid 3-O-sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + a phenolic steroid


name: gamma-lactone-2-keto[5.5.5.5]fenestrane + H(+) + NADPH + O2 => H2O + NADP(+) + penifulvin A


name: RAC2 binds effectors at the plasma membrane (Bos taurus)


name: Autocatalytic phosphorylation of FGFR3c (Drosophila melanogaster)


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Caenorhabditis elegans)


name: hexadecane-1,2-diol + hexadecanoyl-CoA => 2-hydroxyhexadecyl hexadecanoate + CoA


name: H2O + L-saccharopine + NADP(+) = (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH


name: "saccharopine dehydrogenase (NADP(+), L-glutamate-forming)"


name: CLCN4/5/6 exchange Cl- for H+ (Gallus gallus)


name: 2 AH2 + 2 ATP + benzoate + L-phenylalanine <=> 2 A + 2 AMP + 2 diphosphate + H(+) + N-benzoyl-L-phenylalaninol


name: ATP + fluconazole(in) + H2O <=> ADP + fluconazole(out) + H(+) + phosphate


name: Somatostatin receptors bind somatostatin and cortistatin (Sus scrofa)


name: RNF8 and RNF168 ubiquitinate H2AFX (Drosophila melanogaster)


name: (2S)-2-hydroxy-3,3-dimethylbutanenitrile => 2,2-dimethylpropanal + hydrogen cyanide


name: GST dimers conjugate GSH with cytosolic substrates (Sus scrofa)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Canis familiaris)


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Mus musculus)


name: [protein]-C-terminal-L-glutamate + NH4(+) => [protein]-C-terminal-L-glutamine + H2O


name: NFE2L2-dependent GSR gene expression (Homo sapiens)


name: HSF1-mediated gene expression (Drosophila melanogaster)


name: Autophosphorylation of PDGF beta receptors (Xenopus tropicalis)


name: an (E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amine + H(+) + H2O => 2-dehydro-D-glucose + an aliphatic amine


name: H2O + prostaglandin F2alpha 1-glyceryl ester => glycerol + H(+) + prostaglandin F2alpha


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Canis familiaris)


name: NADPH-dependent dihydrocurcumin reductase activity


name: NH4(+) + xanthosine => guanosine + H(+) + H2O


name: Active MTORC1 phosphorylates ULK1 (Mus musculus)


name: CDP-D-glucose => CDP-4-dehydro-6-deoxy-D-glucose + H2O


name: choline + H2O + 2 O2 = glycine betaine + H(+) + 2 H2O2


name: Association of ADAM and B4GALT1 With ZP3 (Bos taurus)


name: A + decanedioyl-CoA <=> (2E)-decenedioyl-CoA + AH2


name: Activated PPARG binds PTEN gene promoter (Homo sapiens)


name: IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)


name: 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol (Bos taurus)


name: Aquaporin-1 passively transports water into cell (Mus musculus)


name: CK1 phosphorylates p-GLI3 (Homo sapiens)


name: Cysteine is degraded to serine and H2S (Xenopus tropicalis)


name: H(+) + N,N-dihydroxy-L-tryptophan => (E)-(indol-3-yl)acetaldehyde oxime + CO2 + H2O


name: NLRC5 binds IKBKB and CHUK (Canis familiaris)


name: G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) (Canis familiaris)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + AH2 + O2 = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + A + 2 H2O


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Dictyostelium discoideum)


name: SUMOyation of DNMT1 with SUMO1 (Sus scrofa)


name: CoA-disulfide + H(+) + NADPH => 2 CoA + NADP(+)


name: a 1-acyl-2-[(7Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Canis familiaris)


name: Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Mus musculus)


name: p-benzoquinone reductase (NADPH) activity


name: beta-lactose + H2O => beta-D-galactose + beta-D-glucose


name: 11-O-acetylcyathatriol + UDP-alpha-D-glucose => erinacine Q2 + H(+) + UDP


name: METAP1/2 demethylates GNAT1 (Bos taurus)


name: A + D-serine + H2O <=> 3-hydroxypyruvate + AH2 + NH4(+)


name: dihydrochelirubine + H(+) + O2 <=> chelirubine + H2O2


name: Formation of clathrin coated vesicle (Sus scrofa)


name: chloride + S-adenosyl-L-methionine => 5'-chloro-5'-deoxyadenosine + L-methionine


name: electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity


name: Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Homo sapiens)


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Schizosaccharomyces pombe)


name: 3-O-(beta-D-xylosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP => L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose


name: TRAF6 binding to activated IRAK2 stimulates its oligomerization (Gallus gallus)


name: aculene C + CO2 + H2O + succinate => 2-oxoglutarate + aculene D + O2


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Sus scrofa)


name: 3-oxooctanedioyl-CoA + CoA = acetyl-CoA + hexanedioyl-CoA


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Canis familiaris)


name: NLRC5 binds IKBKB and CHUK (Gallus gallus)


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Canis familiaris)


name: DHFR dimer reduces FOLA to DHF (Rattus norvegicus)


name: DENND5A,B exchange GTP for GDP on RAB39 (Bos taurus)


name: H(+) + NADH + O2 + urate => 5-hydroxyisourate + H2O + NAD(+)


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Bos taurus)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Drosophila melanogaster)


name: AKT phosphorylates p21Cip1 and p27Kip1 (Rattus norvegicus)


name: TRAF6 polyubiquitinates NRIF (Bos taurus)


name: NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)


name: NAMPT transfers PRIB to NAM to form NAMN (Sus scrofa)


name: 4-aminobutanoate + pyruvate = L-alanine + succinate semialdehyde


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Caenorhabditis elegans)


name: ATP + H2O + sitosterol(in) => ADP + H(+) + phosphate + sitosterol(out)


name: (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + O2 => (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole-[protein] + H2O2


name: 2 H(+) + pterostilbene + 2 S-adenosyl-L-homocysteine => 2 S-adenosyl-L-methionine + trans-resveratrol


name: SARS-CoV-1 nsp1 binds to 40S ribosomal subunit (Homo sapiens)


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine = 1,3,3'-tri-O-methyl-4alpha-mannobiose + H(+) + S-adenosyl-L-homocysteine


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Schizosaccharomyces pombe)


name: desmethyl-dehydrogriseofulvin + S-adenosyl-L-methionine <=> dehydrogriseofulvin + H(+) + S-adenosyl-L-homocysteine


name: 6alpha-hydroxy-28-norcastasterone + O2 + reduced [NADPH--hemoprotein reductase] = 28-norcastasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Bos taurus)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Plasmodium falciparum)


name: EXA4 is converted to EXC4 by LTC4S (Canis familiaris)


name: (4R)-hydroxysphinganine + docosanoyl-CoA <=> CoA + H(+) + N-docosanoyl-(4R)-hydroxysphinganine


name: (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + O2 + reduced [NADPH--hemoprotein reductase] => (20S)-ginsenoside C-K + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA => (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + H(+) + malonyl-CoA


name: all-trans-octaprenol + ATP <=> ADP + all-trans-octaprenyl phosphate + H(+)


name: (6R)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)


name: H2O + hypoxanthine + O2 = H2O2 + xanthine


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O => an N-acylsphing-4-enine + D-galactose


name: IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Sus scrofa)


name: (E)-cinnamaldehyde + hydrogen cyanide => (2S,3E)-2-hydroxy-4-phenylbut-3-enenitrile


name: SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose => a globoside NOR1 (d18:1(4E)) + H(+) + UDP


name: Interaction of SOS with GRB2 bound to FADK1 (Homo sapiens)


name: a 3-oxoacyl-CoA + H(+) + NADH => a (3S)-3-hydroxyacyl-CoA + NAD(+)


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Caenorhabditis elegans)


name: AKAP5 recruits PKC to ROBO3.1 (Canis familiaris)


name: LGI4 binds ADAM22,23,11 (Canis familiaris)


name: cholate + L-serine => H2O + L-serocholate


name: EGFRvIII cancer variant does not bind EGF ligand (Homo sapiens)


name: excitatory extracellular ligand-gated monoatomic ion channel activity


name: ERBB4s80 binds to SRC (Caenorhabditis elegans)


name: AH2 + ATP + 2 Co(II)-[dimethylamine-specific corrinoid protein] + H2O <=> A + ADP + 2 Co(I)-[dimethylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (4R,8Z)-4-hydroxysphing-8-enine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SRC family kinases phosphorylate ERBB2 (Drosophila melanogaster)


name: (+)-5-epi-aristolochene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> capsidiol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: dTDP-alpha-D-fucose + NADP(+) => dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Mus musculus)


name: The 60S subunit joins the translation initiation complex  (Plasmodium falciparum)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Drosophila melanogaster)


name: TULP3 is required for GPR161 localization in the cilium (Gallus gallus)


name: 4,5-dihydroxyphthalate + H(+) + NADH => cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+)


name: 2-propylphenol + H(+) + NADH + O2 <=> 3-propylcatechol + H2O + NAD(+)


name: H2O + N-(9Z-octadecenoyl)-L-glutamate <=> (9Z)-octadecenoate + L-glutamate


name: Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate (Homo sapiens)


name: FAD + H(+) + heptadecanoyl-CoA => FADH2 + trans-2-heptadecenoyl-CoA


name: 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) = 8-epi-inunolide + H2O


name: 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: (E)-4-hydroxynon-2-en-1-ol + NADP(+) => (E)-4-hydroxynon-2-enal + H(+) + NADPH


name: 1-acyl LPE is acylated to PE by LPEAT (Plasmodium falciparum)


name: asnovolin I + S-adenosyl-L-methionine <=> asnovolin K + S-adenosyl-L-homocysteine


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Drosophila melanogaster)


name: cAMP degradation by Phosphodiesterases (Gallus gallus)


name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Xenopus tropicalis)


name: 1-O-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + butanoate + H(+)


name: 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2


name: 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + H(+) + UDP => (E)-coniferaldehyde + UDP-alpha-D-glucose


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: H(+) + N(6)-methyladenosine in U6 snRNA + S-adenosyl-L-homocysteine => adenosine in U6 snRNA + S-adenosyl-L-methionine


name: Cytosolic DUSPs dephosphorylate MAPKs (Xenopus tropicalis)


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Rattus norvegicus)


name: 3-oxopropanoate + H(+) = acetaldehyde + CO2


name: MITF-M-dependent ATP6V1H gene expression (Homo sapiens)


name: H2O + L-seryl-tRNA(Ser) <=> L-serine + tRNA(Ser)


name: GPX5,6 reduce H2O2 to H2O (Mus musculus)


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 24S,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TLR folding by chaperones GP96 and CNPY3 (Sus scrofa)


name: campestanol + O2 + reduced [NADPH--hemoprotein reductase] <=> 6-deoxycathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine <=> 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine


name: ATP + D-erythronate <=> 4-phospho-D-erythronate + ADP + H(+)


name: neurotransmitter transmembrane transporter activity


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> diphosphate + quiannulatene


name: SETD8 monomethylates histone H4 (Rattus norvegicus)


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Plasmodium falciparum)


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Homo sapiens)


name: FOXO1,FOXO3,FOXO4 binds RBL2 gene (Homo sapiens)


name: acetyl-CoA + L-2,4-diaminobutanoate => (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: H2O + succinyl-CoA = CoA + H(+) + succinate


name: (+)-lariciresinol + NADP(+) = (+)-pinoresinol + H(+) + NADPH


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Danio rerio)


name: (1S,4S)-5-oxo-1,2-campholide = [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)


name: 2-amino-2-deoxy-D-gluconate = (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate + H2O


name: ADP + H(+) + L-arabinose(in) + phosphate => ATP + H2O + L-arabinose(out)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol


name: (R)-carnitine(in) + ADP + H(+) + phosphate => (R)-carnitine(out) + ATP + H2O


name: (2-aminoethyl)phosphonate + pyruvate => L-alanine + phosphonoacetaldehyde


name: Translocation of COP1 from the nucleus to the cytoplasm (Sus scrofa)


name: HCO3- transport through ion channel (Sus scrofa)


name: H2O + L-tryptophanamide <=> L-tryptophan + NH4(+)


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycerol + CDP-N-methylethanolamine = 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + CMP + H(+)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Mus musculus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Saccharomyces cerevisiae)


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Saccharomyces cerevisiae)


name: D-glutamine + H2O + O2 => 2-oxoglutaramate + H2O2 + NH4(+)


name: H2O + N-(9Z-octadecenoyl)-L-tryptophan = (9Z)-octadecenoate + L-tryptophan


name: PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Sus scrofa)


name: (12R)-hydroxy-(9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphocholine => (12R-hydroxy-9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: UDP-alpha-D-glucuronate + zolasartan => UDP + zolarsartan-1-N-beta-D-glucuronide


name: (1S)-3-methyl-cyclohexylamine + H2O + NAD(+) = 3-methylcyclohexanone + H(+) + NADH + NH4(+)


name: anthranilate + H(+) + octanoate => H2O + N-octanoylanthranilate


name: (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+) => H2O + L-isoleucine + O2


name: Polyubiquitinated NRIF binds to p62 (Sequestosome) (Canis familiaris)


name: protein-arginine omega-N asymmetric methyltransferase activity


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Drosophila melanogaster)


name: Defective RB1 does not bind E2F1,(E2F2,E2F3) (Homo sapiens)


name: MITF-M dimer, SOX10, pS133 CREB1 and CTNNB1:LEF1 bind the DCT gene (Homo sapiens)


name: CD320 binds extracellular TCN2:RCbl (Canis familiaris)


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Canis familiaris)


name: SPINK5(490-624) binds KLK5 (Homo sapiens)


name: PHF8 demethylates MeK21-histone H4 (Canis familiaris)


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Rattus norvegicus)


name: 2-hydroxyglutarate + acetyl-CoA = 2-hydroxyglutaryl-CoA + acetate


name: 2 Fe(III)-[cytochrome c] + H2O + pseudooxynicotine = 4-oxo-4-(pyridin-3-yl)butanal + 2 Fe(II)-[cytochrome c] + 2 H(+) + methylamine


name: beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose <=> alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP + H(+)


name: USP17L2 deubiquitinates RCE1 (Rattus norvegicus)


name: naphtopyrone YWA1 = H(+) + H2O + norrubrofusarin


name: Formation of Elongin BC complex (Mus musculus)


name: (R)-lactate + 2 Fe(III)-[cytochrome c] => 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Dictyostelium discoideum)


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Gallus gallus)


name: 2-aminobenzimidazole + CO2 => H(+) + N-(1H-1,3-benzodiazol-2-yl)carbamate


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Bos taurus)


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Caenorhabditis elegans)


name: USP4 deubiquitinate TRAF2,TRAF6 (Gallus gallus)


name: H(+)(out) + N-acetylneuraminate(out) => H(+)(in) + N-acetylneuraminate(in)


name: 3-deoxyglucosone + H(+) + NADPH => 3-deoxyfructose + NADP(+)


name: 2-oxoglutarate + O2 + phytanoyl-CoA => 2-hydroxyphytanoyl-CoA + CO2 + succinate


name: Cytosolic folate export across the plasma membrane (Saccharomyces cerevisiae)


name: 2'-O-methyluridine(2791) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(2791) in 21S rRNA


name: COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates (Danio rerio)


name: TFAP2C translocates to the nucleus (Xenopus tropicalis)


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na(+)(in) <=> 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na(+)(out)


name: uridine(35) in tRNA(Tyr) <=> pseudouridine(35) in tRNA(Tyr)


name: (20S)-ginsenoside Rb1 + H2O => (20S)-ginsenoside Rd + D-glucose


name: 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + L-alanine = [5-(aminomethyl)-3-furyl]methyl phosphate + pyruvate


name: (3R)-hydroxy-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+) => 3-oxo-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H(+) + NADPH


name: N-methyl-L-dopa + O2 <=> (3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2


name: p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus (Caenorhabditis elegans)


name: Degradation of multiubiquitinated Cdh1 (Homo sapiens)


name: norcoclaurine + S-adenosyl-L-methionine <=> coclaurine + H(+) + S-adenosyl-L-homocysteine


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Caenorhabditis elegans)


name: 3'-phosphoadenylyl sulfate + 3,3',5'-triiodo-L-thyronine <=> 3,3',5'-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Danio rerio)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Homo sapiens)


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Rattus norvegicus)


name: Ca impermeable AMPA receptor ligand binding (Sus scrofa)


name: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP


name: SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Gallus gallus)


name: p-FRS2:CRKL binds C3G (Rattus norvegicus)


name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: mycophenolate + UDP-alpha-D-glucuronate => H(+) + mycophenolate 7-O-beta-D-glucuronide + UDP


name: RNA Pol II initiates transcription from damaged DNA template (Canis familiaris)


name: 3-hydroxy-5-methyl-1-naphthoate + H2O + NADP(+) => 5-methyl-1-naphthoate + H(+) + NADPH + O2


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Rattus norvegicus)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Danio rerio)


name: GDIs block activation of RHOB (Rattus norvegicus)


name: C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Drosophila melanogaster)


name: Homer1,2,3 binds mGluR1a,5 (Canis familiaris)


name: acetyl-CoA + gentamicin C <=> CoA + H(+) + N(3)-acetylgentamycin C


name: TNFSF11 binds TNFRSF11A, B (Homo sapiens)


name: PLC-gamma1 hydrolyses PIP2 (Plasmodium falciparum)


name: alpha,alpha-trehalose 6-phosphate(in) + L-histidyl-[protein] => alpha,alpha-trehalose(out) + N(pros)-phospho-L-histidyl-[protein]


name: ent-copalyl diphosphate => diphosphate + dolabradiene


name: H(+) + testosterone 17-O-(beta-D-glucuronate) + UDP => testosterone + UDP-alpha-D-glucuronate


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Bos taurus)


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Canis familiaris)


name: LAG3 (CD233) binds MHC II (Canis familiaris)


name: G or G analog binds C-ter TLR7 dimer (Xenopus tropicalis)


name: a quinone + shikimate = 3-dehydroshikimate + a quinol


name: (E)-7-(methylsulfanyl)heptanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => L-tetrahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: (2R)-3-sulfolactate => H(+) + pyruvate + sulfite


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Danio rerio)


name: low-affinity L-arginine transmembrane transporter activity


name: SIRT1 deacetylates HINT1 dimer (Homo sapiens)


name: p-PKR dimer phosphorylates SPHK1 (Mus musculus)


name: 3-hydroxy-L-kynurenine + H2O + NADP(+) => H(+) + L-kynurenine + NADPH + O2


name: Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1 (Homo sapiens)


name: (2E)-docosenoyl-CoA + H(+) + NADPH = docosanoyl-CoA + NADP(+)


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: Recruitment of elongation factors to form elongation complex (Canis familiaris)


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Bos taurus)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Mus musculus)


name: ASIC3 channel blockers bind ASIC3 trimer (Canis familiaris)


name: cholate + L-arginine = H2O + L-arginocholate


name: apoA-I binds to CUBN:AMN (Rattus norvegicus)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA <=> [N,O(9)-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Bos taurus)


name: MCAT transfers Mal from Mal-CoA to NDUFAB1 (Saccharomyces cerevisiae)


name: RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)


name: a menaquinone + 2 H(+)(out) + H2O + nitrite => a menaquinol + 2 H(+)(in) + nitrate


name: CO2 + 2 Na(+)(out) + pyruvate => H(+) + 2 Na(+)(in) + oxaloacetate


name: 2 S-adenosyl-L-methionine + tricetin => 3',5'-di-O-methyltricetin + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: carbon disulfide + H2O = carbonyl sulfide + H(+) + hydrogen sulfide


name: 3-oxobutanoyl-[ACP] + acetyl-[ACP] + H2O <=> (3S)-hydroxy-3-methylglutaryl-[ACP] + H(+) + holo-[ACP]


name: RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Sus scrofa)


name: p115-RhoGEF activation of RHOA (Drosophila melanogaster)


name: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol


name: RUNX2 binds SMAD1 in the nucleus (Mus musculus)


name: acryloyl-CoA + H(+) + NADPH => NADP(+) + propanoyl-CoA


name: GRB2-1:SOS1 binds p-Y427-SHC1 (Canis familiaris)


name: L-kynurenine(out) + L-tryptophan(in) = L-kynurenine(in) + L-tryptophan(out)


name: 5,10-methylenetetrahydromethanopterin + NAD(+) => 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH


name: Pink1 is recruited from the cytoplasm to the mitochondria (Homo sapiens)


name: 2,6,10,14-tetramethylpentadecanoate + CoA + H(+) => H2O + pristanoyl-CoA


name: Adenylate cyclase produces cAMP (Sus scrofa)


name: 4alpha-carboxyzymosterol + NAD(+) => CO2 + NADH + zymosterone


name: ADP + H(+) + O-phospho-L-seryl-[rhodopsin] => ATP + L-seryl-[rhodopsin]


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Homo sapiens)


name: Recruitment of ITCH and K48 ubiquitination of MAVS (Homo sapiens)


name: ADP + glycyl-L-glutamate(in) + H(+) + phosphate => ATP + glycyl-L-glutamate(out) + H2O


name: Cho transports from the extracellular space to the cytosol (Mus musculus)


name: glycylglycyl-L-isoleucine(in) + H(+)(in) => glycylglycyl-L-isoleucine(out) + H(+)(out)


name: dihydroxyacetone phosphate + iminosuccinate = H(+) + 2 H2O + phosphate + quinolinate


name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin (Mus musculus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O <=> an N-acylsphing-4-enine + D-glucose


name: WNT ligands traffic to the plasma membrane (Sus scrofa)


name: MDH1 reduces OA (Dictyostelium discoideum)


name: Receptor FFAR1 binds free fatty acids (Mus musculus)


name: an N-acyl-sphinga-4E,14Z-dienine + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 2 Na(+)(out) + testosterone 17-sulfate(out) = 2 Na(+)(in) + testosterone 17-sulfate(in)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Canis familiaris)


name: cholesterol + O2 = cholest-5-en-3-one + H2O2


name: Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (Rattus norvegicus)


name: prostaglandin A2-S-(S)-glutathione => glutathione + prostaglandin A2


name: (4R)-hydroxyeicosasphinganine + hexacosanoyl-CoA => CoA + H(+) + N-hexacosanoyl-eicosan-(4R)-hydroxysphinganine


name: FOLR2 transports FOLA from extracellular region to cytosol (Canis familiaris)


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Mus musculus)


name: ADP + dimethylallyl diphosphate <=> diphosphate + N(6)-(dimethylallyl)adenosine 5'-diphosphate


name: DCC interaction with SIAH1 (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: acetoin + CoA + NAD(+) => acetaldehyde + acetyl-CoA + H(+) + NADH


name: PE is methylated to PC by PEMT (Bos taurus)


name: 2-dehydro-3-deoxy-L-rhamnonate + NAD(+) => 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Canis familiaris)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Danio rerio)


name: RHOD auto-activates (Saccharomyces cerevisiae)


name: ATP + glycine betaine(out) + H2O => ADP + glycine betaine(in) + H(+) + phosphate


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Xenopus tropicalis)


name: KCNK dimers transport K+ from cytosol to extracellular region (Saccharomyces cerevisiae)


name: Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton (Bos taurus)


name: colupulone + diphosphate + H(+) => deoxycohumulone + dimethylallyl diphosphate


name: an (E)-omega-(methylsulfanyl)-alkanal oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] <=> an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: gibberellin A24 + H(+) + O2 <=> CO2 + gibberellin A9 + H2O


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Danio rerio)


name: H2O + methylglyoxal <=> (R)-lactate + H(+)


name: 3alpha,7beta-dihydroxy-12-oxo-5beta-cholan-24-oate + NADP(+) <=> 7,12-dioxo-lithocholate + H(+) + NADPH


name: KCNK dimers transport K+ from cytosol to extracellular region (Drosophila melanogaster)


name: (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 = (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Xenopus tropicalis)


name: Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 (Drosophila melanogaster)


name: acetate + ADP-D-ribose + H(+) => 3''-O-acetyl-ADP-D-ribose + H2O


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose => a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N(omega)-hydroxy-L-arginine => 2 Fe(III)-[cytochrome b5] + H2O + L-arginine


name: FUT1,2 transfer fucose to gangliosides (Xenopus tropicalis)


name: Formation of DRIP coactivator complex (Gallus gallus)


name: 3-hydroxypropanoate + NADP(+) => 3-oxopropanoate + H(+) + NADPH


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + S-adenosyl-L-methionine = griseophenone D + H(+) + S-adenosyl-L-homocysteine


name: H(+)(in) + novobiocin(out) => H(+)(out) + novobiocin(in)


name: Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR) (Homo sapiens)


name: 3-(methylsulfanyl)acryloyl-CoA + H2O <=> 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA


name: Group 3 - Selective Cl- transport (Saccharomyces cerevisiae)


name: NR3C2 binds NR3C2 antagonists (Rattus norvegicus)


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Drosophila melanogaster)


name: ER calcium channels open in response to activated PKA (Canis familiaris)


name: H(+) + sucrose + UDP => D-fructose + UDP-alpha-D-glucose


name: Proton-coupled di- and tri-peptide cotransport (Dictyostelium discoideum)


name: dodecanoate + 2 H(+) + NADH = dodecanal + H2O + NAD(+)


name: LGI4 binds ADAM22,23,11 (Rattus norvegicus)


name: mogrol + UDP-alpha-D-glucose <=> H(+) + mogroside IE + UDP


name: diphosphate + H(+) + N(epsilon)-GMP-L-lysyl-[protein] => GTP + L-lysyl-[protein]


name: MFSD2A transports LPC from extracellular region to plasma membrane (Rattus norvegicus)


name: 5-methyl-2-thiouridine(54) in tRNA + [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + AMP + diphosphate + 2 H(+) => 5-methyluridine(54) in tRNA + [TtuB sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + ATP + H2O


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Gallus gallus)


name: p-Y701-STAT1 binds p-Y705-STAT3 (Caenorhabditis elegans)


name: all-trans-nonaprenyl diphosphate + H(+) + homogentisate <=> 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate


name: phycoviolobilin-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit] = (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit]


name: "phycoerythrocyanin alpha-cysteine-84 phycoviolobilin lyase/isomerase"


name: dodecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-undecylpyran-2-one + 2 CO2 + 3 CoA


name: Expression of lymphocyte cytosolic protein 1 (Homo sapiens)


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Sus scrofa)


name: dehydroepiandrosterone 3-sulfate + O2 + reduced [NADPH--hemoprotein reductase] <=> 16alpha-hydroxydehydroepiandrosterone 3-sulfate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GEF binds to the inactive DRheb (Drosophila melanogaster)


name: 4-hydroxy-all-trans-beta-carotene + AH2 + O2 => 4,4-dihydroxy-all-trans-beta-carotene + A + H2O


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Xenopus tropicalis)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Mus musculus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol <=> 2-hexadecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl hexadecanoate


name: 4-hydroxy-2-oxohexanoate => (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H2O


name: Formation of the RBBP5:ASH2L heterodimer (Mus musculus)


name: TXNIP binds reduced thioredoxin (Saccharomyces cerevisiae)


name: GALNT3 transfers GalNAc to FGF23 (Drosophila melanogaster)


name: Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions (Sus scrofa)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Drosophila melanogaster)


name: a 12-oxojasmonyl-L-alpha-amino acid + O2 + reduced [NADPH--hemoprotein reductase] => a 12-hydroxy-12-oxojasmonyl-L-alpha-amino acid + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: N(5)-hydroxy-L-ornithine => (3S)-1,2-diazinane-3-carboxylate + H(+) + H2O


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 10,11-epoxy-(7Z,13Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) (Homo sapiens)


name: CoA + H(+) + N-octanoylglycine => glycine + octanoyl-CoA


name: ATP + L-serine + tRNA(Ser) <=> AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)


name: CDC42:GTP binds CBL:Beta-Pix (Gallus gallus)


name: H2O + Met-enkephalin-Arg-Phe => L-arginyl-L-phenylalanine + Met-enkephalin


name: Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Drosophila melanogaster)


name: Activated FGFR3:p-FRS bind to PPTN11 (Gallus gallus)


name: (R)-carnitine + hexanoyl-CoA <=> CoA + O-hexanoyl-(R)-carnitine


name: nigerose + phosphate = beta-D-glucose 1-phosphate + D-glucose


name: gibberellin A12 aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => ent-7alpha-hydroxykaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: 20-methyl-21,22-didehydro-20,21-dihydrobotryococcene + H(+) + S-adenosyl-L-homocysteine => C30 botryococcene + S-adenosyl-L-methionine


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP => 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: JAK1 phosphorylates STAT3,STAT6 (Sus scrofa)


name: 6-hydroxymellein + S-adenosyl-L-methionine <=> 6-methoxymellein + H(+) + S-adenosyl-L-homocysteine


name: dUTP + H2O => dUMP + pyrophosphate (Drosophila melanogaster)


name: 1,4-dihydroxy-2-naphthoyl-CoA + H2O <=> 1,4-dihydroxy-2-naphthoate + CoA + H(+)


name: PPM1A dephosphorylates nuclear SMAD2/3 (Drosophila melanogaster)


name: 2 5,6-dihydroxyindole + O2 => 2 H2O + 2 indole-5,6-quinone


name: Interleukin-12 dissociates from Interleukin-12 receptor (Sus scrofa)


name: enterobactin + 3 H2O <=> 2 H(+) + 3 N-(2,3-dihydroxybenzoyl)-L-serine


name: epidermal growth factor receptor binding


name: USP8 deubiquitinates RNF128 (Canis familiaris)


name: 5,6-dihydrouridine(17) in tRNA + NADP(+) => H(+) + NADPH + uridine(17) in tRNA


name: Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol (Canis familiaris)


name: (2R,3R)-dihydroquercetin + CO2 + succinate => (S)-eriodictyol + 2-oxoglutarate + O2


name: naphthalene disulfonate 1,2-dioxygenase activity


name: phthalate 3,4-cis-dihydrodiol dehydrogenase activity


name: Active PLC-gamma1 dissociates from EGFR (Canis familiaris)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Sus scrofa)


name: ATP + beta-alanine + L-ornithine => ADP + beta-alanyl-L-ornithine + H(+) + phosphate


name: D-xylose + H(+) + NADPH => NADP(+) + xylitol


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Bos taurus)


name: D-lysine(in) + L-ornithine(out) = D-lysine(out) + L-ornithine(in)


name: PP6 dephosphorylates SEC24 (Rattus norvegicus)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: TGFBR2 phosphorylates TGFBR1 and PARD6A (Homo sapiens)


name: Cysteine is degraded to serine and H2S (Danio rerio)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Xenopus tropicalis)


name: SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Mus musculus)


name: E1 mediated ubiquitin activation (Homo sapiens)


name: beta-alanine(in) + L-alanine(out) => beta-alanine(out) + L-alanine(in)


name: Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Mus musculus)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Homo sapiens)


name: SARS-CoV-2 3CLpro dimer cleaves NLRP12 (Homo sapiens)


name: Transport of SEC22B, TAP and PLC from ER to ERGIC (Homo sapiens)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Sus scrofa)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity


name: L-tryptophan + O2 = N-formyl-L-kynurenine


name: nucleoside transmembrane transporter activity, down a concentration gradient


name: Activation of Edited Kainate receptors (Bos taurus)


name: mycothiol is cleaved to acetylcysteine and glucosaminylinositol (Mycobacterium tuberculosis)


name: 3-sulfinopropanoyl-CoA + H2O => H(+) + propanoyl-CoA + sulfite


name: 2-dehydropantoate + H(+) + NADH => (R)-pantoate + NAD(+)


name: (2E,6E)-farnesyl diphosphate => cis-muurola-3,5-diene + diphosphate


name: a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+) => 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-epicubenol + diphosphate


name: 3' incision by ERCC5 (XPG) in TC-NER (Mus musculus)


name: 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate = (2S)-3-sulfolactaldehyde + pyruvate


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Homo sapiens)


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Bos taurus)


name: Activated CIT binds KIF14 and PRC1 (Mus musculus)


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Rattus norvegicus)


name: 3,4-dihydroxy-2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide => aurachin B + H(+) + H2O


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Homo sapiens)


name: CUL9:RBX1 ubiquitinates BIRC5 (Bos taurus)


name: Release of noradrenaline  at the synapse (Drosophila melanogaster)


name: Exogenous soluble antigen targeted to more stable early endosome (Bos taurus)


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Gallus gallus)


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Mus musculus)


name: (3R)-hydroxy-(13Z)-docosenoyl-CoA + NADP(+) => (13Z)-3-oxodocosenoyl-CoA + H(+) + NADPH


name: 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n) => H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline


name: Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Caenorhabditis elegans)


name: CLK and CYC bind to form a heterodimer (Drosophila melanogaster)


name: (6R)-10-formyltetrahydrofolate + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose => (6S)-5,6,7,8-tetrahydrofolate + dTDP-4-formamido-4,6-dideoxy-alpha-D-glucose + H(+)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: L-glutamate(out) + L-thyroxine(in) => L-glutamate(in) + L-thyroxine(out)


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Canis familiaris)


name: hexadecanoyl-CoA + taurine = CoA + H(+) + N-hexadecanoyl-taurine


name: Disassembly of COPII coated vesicle (Canis familiaris)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Schizosaccharomyces pombe)


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Caenorhabditis elegans)


name: 1,6-dihydroxyphenazine + S-adenosyl-L-methionine = 1-hydroxy-6-methoxyphenazine + H(+) + S-adenosyl-L-homocysteine


name: C-ter TLR7 dimer binds HCQ (Canis familiaris)


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Homo sapiens)


name: citrate(in) + H(+)(in) = citrate(out) + H(+)(out)


name: Phosphorylated PKN1 binds androgen receptor (AR) (Canis familiaris)


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Saccharomyces cerevisiae)


name: GDIs block activation of RHOB (Mus musculus)


name: enterobactin transmembrane transporter activity


name: DCP1-DCP2 complex decaps mRNA (Sus scrofa)


name: Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)


name: PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)


name: Sema3A binds Nrp-1 bound to PlexinA (Bos taurus)


name: MBTPS2 (S2P) cleaves CREB3L3 (Canis familiaris)


name: glyoxylate + L-alanine = glycine + pyruvate


name: Recruitment of BCAR1 to PTK2 complex (Homo sapiens)


name: TP53 stimulates MDM2 transcription (Homo sapiens)


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Rattus norvegicus)


name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene (Homo sapiens)


name: ethanolamine + H2O + O2 <=> glycolaldehyde + H2O2 + NH4(+)


name: Association of procollagen type VIII (Canis familiaris)


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Homo sapiens)


name: L-idonate + NAD(+) <=> 2-dehydro-L-idonate + H(+) + NADH


name: p-STAT1:p-STAT4 translocates to the nucleus (Mus musculus)


name: 5alpha-ergosta-7,22-diene-3beta,5-diol => ergosterol + H2O


name: Docking of Mature Replication Dependent Histone mRNA with the NPC (Mus musculus)


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA1 (d18:1(4E)/18:0) => CMP + ganglioside GM1 (d18:1(4E)/18:0) + H(+)


name: (2R,3R)-dihydrokaempferol + O2 + reduced [NADPH--hemoprotein reductase] => (2R,3R)-dihydroquercetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Recruitment of GRB2 to p-PTK2 (Mus musculus)


name: Myosin phosphatase dephosphorylates PLK1 (Bos taurus)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Mus musculus)


name: Cleavage of uracil by UNG glycosylase (Homo sapiens)


name: H2O + hexanoyl-CoA => CoA + H(+) + hexanoate


name: Tyrosinase oxidises tyrosine to dopaquinone (Homo sapiens)


name: a fatty acid + a monoacylglycerol + H(+) => a 1,3-diacyl-sn-glycerol + H2O


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-sn-glycero-3-phosphocholine


name: 2 H(+)(in) + L-alanyl-L-alanine(in) => 2 H(+)(out) + L-alanyl-L-alanine(out)


name: Secretion and activation of the latent large complex of TGF-beta-1 (Rattus norvegicus)


name: (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (22R,23R)-22,23-dihydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + a 1-acyl-sn-glycero-3-phosphocholine + H(+) => 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O


name: CYP26C1 4-hydroxylates 9cRA (Sus scrofa)


name: 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity


name: CSNK1G2 phosphorylates p-CERT1-2 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-epi-alpha-bisabolol + diphosphate


name: (Z)-dehydrocyclopeptine + 2-oxoglutarate + O2 <=> (-)-cyclopenine + CO2 + succinate


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-[ACP] <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + holo-[ACP]


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Rattus norvegicus)


name: AH2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3] => A + H2O + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3]


name: mRNP complex dissociates from cytosolic face of NPC (Drosophila melanogaster)


name: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialurate + H(+)


name: Phosphorylation of DCC by Fyn (Danio rerio)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Bos taurus)


name: Membrane estrogen receptors bind SRC (Mus musculus)


name: HSF1 trimer translocates to the nucleus (Caenorhabditis elegans)


name: 2 H(+)(out) + serotonin(in) => 2 H(+)(in) + serotonin(out)


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoyl-CoA + AMP + diphosphate => (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + ATP + CoA


name: H2O + propanoyl-CoA => CoA + H(+) + propanoate


name: Nuclear PP2A dephosphorylates phosphorylated PER (Drosophila melanogaster)


name: GUSB tetramer hydrolyses (HA)2 (Sus scrofa)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Caenorhabditis elegans)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Canis familiaris)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Bos taurus)


name: (2E)-geranial + H(+) + NADPH => (2E)-geraniol + NADP(+)


name: phenazine-1-carboxylate + S-adenosyl-L-methionine = 5-methyl-phenazine-1-carboxylate + S-adenosyl-L-homocysteine


name: H2O + L-ectoine = (2S)-2-acetamido-4-aminobutanoate


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Caenorhabditis elegans)


name: beta-casomorphin-7 + H2O <=> beta-casomorphin-6 + L-isoleucine


name: acetyl-CoA + N-terminal L-methionyl-[tubulin] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]


name: "tubulin N-terminal N-acetyltransferase NAT9"


name: (2S,4S,5S)-2-amino-6-(3,4-dihydroxyphenyl)-4-hydroxy-5-(methylamino)hexanoyl-[peptidyl-carrier protein] + O2 <=> (2S,4S)-2-amino-4-[(3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl]-4-hydroxybutanoyl-[peptidyl-carrier protein] + H2O2


name: Retrograde COPI vesicles bind kinesin and microtubules (Mus musculus)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + H(+) + NADPH => 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP(+)


name: H(+) + UDP + validamycin A => UDP-alpha-D-glucose + validoxylamine A


name: Abortive initiation after formation of the first phosphodiester bond (Dictyostelium discoideum)


name: D-glucuronate(out) + H(+)(out) <=> D-glucuronate(in) + H(+)(in)


name: Interaction of NCAM1 with collagens (Rattus norvegicus)


name: The PIDDosome activates CASP2 (Bos taurus)


name: SIRPA binds SFTPA oligomer, SFTPD oligomer (Sus scrofa)


name: Formation of the SET1A complex (Caenorhabditis elegans)


name: NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP (Rattus norvegicus)


name: MTORC1 dissociates from ULK complex (Bos taurus)


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Xenopus tropicalis)


name: ERCC5 and RPA bind TC-NER site (Mus musculus)


name: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> all-trans-4-hydroxyretinol + H2O + 2 oxidized [adrenodoxin]


name: H2O + sn-glycero-3-phosphoethanolamine => ethanolamine + H(+) + sn-glycerol 3-phosphate


name: ubiquitin-modified histone reader activity


name: ATP + H2O + N-all-trans-retinylidenephosphatidylethanolamine(out) => ADP + H(+) + N-all-trans-retinylidenephosphatidylethanolamine(in) + phosphate


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: Interaction of DAP12 and KIR2DS5 (Rattus norvegicus)


name: cytidine(38) in tRNA + S-adenosyl-L-methionine => 5-methylcytidine(38) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4 (Homo sapiens)


name: 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP => 2-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Saccharomyces cerevisiae)


name: COX18 inserts nascent MT-CO2 in COX20:TMEM77 (Rattus norvegicus)


name: Phosphorylation of SHC1 (Rattus norvegicus)


name: Group 3 - Selective Cl- transport (Gallus gallus)


name: coproporphyrin I(out) <=> coproporphyrin I(in)


name: Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Homo sapiens)


name: AMP + glutathione disulfide + 2 H(+) + sulfite <=> adenosine 5'-phosphosulfate + 2 glutathione


name: SGTA binds Tail-anchored protein (Xenopus tropicalis)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Xenopus tropicalis)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Drosophila melanogaster)


name: 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+) => 5-pyridoxate + NADPH + O2


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Bos taurus)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: XDH dehydrogenates xanthine to form urate (Canis familiaris)


name: Formation of ORC(2-5) complex (Xenopus tropicalis)


name: NR3C2 binds fludrocortisone (Xenopus tropicalis)


name: Formation of eIF2:GDP:eIF2B intermediate (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)


name: 2-oxoglutarate + L-ornithine + O2 = (3S)-3-hydroxy-L-ornithine + CO2 + succinate


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Homo sapiens)


name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Schizosaccharomyces pombe)


name: ADP + ergothioneine(in) + H(+) + phosphate => ATP + ergothioneine(out) + H2O


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Homo sapiens)


name: RAPGEF1 binds CRK,CRKL (Rattus norvegicus)


name: SUMOylation of NR1I2 with SUMO3 (Mus musculus)


name: 2 a 1-acylglycerol = a 1,2-diacylglycerol + glycerol


name: SPI1 (PU.1) gene transcription is stimulated by RUNX1:CBFB:KMT2A (Homo sapiens)


name: 3-methylcyclopentanone + H(+) + NADPH + NH4(+) => 3-methylcyclopentanamine + H2O + NADP(+)


name: a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + H(+) + UDP => a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose


name: C3d-complexed antigen binds to complement receptor (Mus musculus)


name: aldosterone + H(+) + NADPH <=> 5beta-dihydroaldosterone + NADP(+)


name: RHOA:GTP:RTKN binds TAX1BP3 (Homo sapiens)


name: CoA + H(+) + N-acetylnoradrenaline => acetyl-CoA + noradrenaline


name: BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. (Homo sapiens)


name: H(+) + ilicicolin A epoxide + NADPH + O2 <=> 16-hydroxy-ilicicolin A epoxide + H2O + NADP(+)


name: Fall Back to Closed Pre-initiation Complex (Sus scrofa)


name: 4-aminobutanoate + glyoxylate = glycine + succinate semialdehyde


name: acetyl-CoA + tetradecanoyl-CoA = 3-oxohexadecanoyl-CoA + CoA


name: 3 2-oxoglutarate + gibberellin A53 + 3 O2 = 3 CO2 + gibberellin A17 + H(+) + H2O + 3 succinate


name: GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Sus scrofa)


name: CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Gallus gallus)


name: (+)-pinoresinol + O2 + reduced [NADPH--hemoprotein reductase] = (+)-piperitol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + H(+) + phosphate => (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ATP + L-glutamate


name: eIF2:GTP is hydrolyzed, eIFs are released  (Homo sapiens)


name: transmembrane receptor protein tyrosine kinase adaptor activity


name: H(+) + NADPH + pent-1-en-3-one => NADP(+) + pentan-3-one


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Caenorhabditis elegans)


name: The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds E2F1 gene promoter (Homo sapiens)


name: H2O + NADP(+) + semiviriditoxin => (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + H(+) + NADPH + O2


name: ATP(in) + CoA(in) + H(+)(out) + tetradecanoate(out) = AMP(in) + diphosphate(in) + H(+)(in) + tetradecanoyl-CoA(in)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Caenorhabditis elegans)


name: WNT binds to FZD and LRP5/6 (Homo sapiens)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Caenorhabditis elegans)


name: Telomere shortening during replicative exhaustion (Sus scrofa)


name: PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2) => H2O + N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,2)


name: Association of cell cycle proteins with the APC/C:Cdh1 complex (Dictyostelium discoideum)


name: Furin cleaves pro-protein S to protein S (Xenopus tropicalis)


name: a 2-halobenzoate + H(+) + NADH + O2 <=> a halide anion + catechol + CO2 + NAD(+)


name: 4 (S)-methylmalonyl-CoA + 4-nitrobenzoyl-CoA + 8 H(+) + malonyl-CoA + 4 NADPH => 5 CO2 + 6 CoA + demethylluteothin + 3 H2O + 4 NADP(+)


name: AMP(in) + diphosphate(in) + H(+)(in) + hexadecanoyl-CoA(in) => ATP(in) + CoA(in) + H(+)(out) + hexadecanoate(out)


name: docosanoyl-CoA + glycine => CoA + H(+) + N-docosanoylglycine


name: glycolate + GMP + H(+) => H2O + N(2)-(1-hydroxy-2-oxoethyl)-GMP


name: (E)-4-coumaroyl-CoA + H2O => 3-hydroxy-3-(4-hydroxyphenyl)propanoyl-CoA


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Plasmodium falciparum)


name: 7(1)-hydroxychlorophyllide a + NADP(+) <=> chlorophyllide b + H(+) + NADPH


name: eicosanoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (5Z)-eicosenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2-oxoglutarate(out) + 3 Na(+)(out) <=> 2-oxoglutarate(in) + 3 Na(+)(in)


name: 6-methylthiopropyl glucosinolate S-oxygenase activity


name: adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Bos taurus)


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)


name: [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein] => [thioredoxin]-disulfide + H2O + L-methionyl-[protein]


name: RHOA:GTP binds ROCK, activating it (Sus scrofa)


name: H2O + iminosuccinate <=> NH4(+) + oxaloacetate


name: (2R,3R)-tartrate(in) + sulfate(out) => (2R,3R)-tartrate(out) + sulfate(in)


name: H2O + prostaglandin D2-1-glycerol ester = glycerol + H(+) + prostaglandin D2


name: DIMBOA + UDP-alpha-D-glucose => DIMBOA beta-D-glucoside + H(+) + UDP


name: decanoyl-CoA + glycine => CoA + H(+) + N-decanoylglycine


name: asperlicin C + H(+) + NADPH + O2 => asperlicin E + H2O + NADP(+)


name: [(2->1)-beta-D-fructosyl](n+1) + D-glucose => [(2->1)-beta-D-fructosyl](n) + sucrose


name: an N-acetyl-alpha-D-glucosaminyl derivative + UDP-alpha-D-galactose <=> a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl derivative + H(+) + UDP


name: Activated FGFR1 phosphorylates FRS2 (Gallus gallus)


name: Nociceptin receptor binds to nociceptin (Gallus gallus)


name: VAV3 is a GEF for Rho/Rac family kinases (Mus musculus)


name: PG and CDP-DAG are converted to CL by CRLS1 (Caenorhabditis elegans)


name: ITPA hydrolyses dITP to dIMP (Plasmodium falciparum)


name: ACSF2 ligates CoA-SH to MCFA (Mus musculus)


name: BIRC(cIAP1/2) ubiquitinates RIPK1 (Mus musculus)


name: deoxynogalonate + O2 <=> H(+) + H2O + nogalonate


name: Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Rattus norvegicus)


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Rattus norvegicus)


name: Aquaporins passively transport water out of cells (Plasmodium falciparum)


name: a 1,2-saturated fatty acid + O2 <=> a (2R)-2-hydroperoxy fatty acid


name: PAF receptor binds platelet activating factor (Gallus gallus)


name: LKB1 forms a trimeric complex with STRAD and MO25 (Sus scrofa)


name: 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA <=> 4-hydroxybenzalacetone + 2 CO2 + 2 CoA


name: high-affinity glucose:proton symporter activity


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP => 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: CO2 + formaldehyde + oripavine + succinate => 2-oxoglutarate + O2 + thebaine


name: COX10 transforms heme to heme O (Xenopus tropicalis)


name: desmethylnectriapyrone + S-adenosyl-L-methionine <=> H(+) + nectriapyrone + S-adenosyl-L-homocysteine


name: 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP => pyridoxine + UDP-alpha-D-glucose


name: 5''-phosphoribostamycin + H2O => phosphate + ribostamycin


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Sus scrofa)


name: H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate


name: 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol + 2 Fe(III)-[cytochrome b5] + H2O


name: glycyl-sarcosine(out) + H(+)(out) => glycyl-sarcosine(in) + H(+)(in)


name: H(+) + ladanein + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + scutellarein 7-methyl ether


name: (2R)-2,3-bisphosphoglycerate + ADP + H(+) => (2R)-2-phosphoglycerate + ATP


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + [thyroglobulin]-3-iodo-L-tyrosine + H2O2 <=> [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O


name: L-dopa(out) + L-phenylalanine(in) = L-dopa(in) + L-phenylalanine(out)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Bos taurus)


name: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde => 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Xenopus tropicalis)


name: SHPRH polyubiquitinates monoubiquitinated PCNA (Bos taurus)


name: 17alpha-estradiol 3-O-(beta-D-glucuronate) + UDP-N-acetyl-alpha-D-glucosamine => 17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucosiduronate + H(+) + UDP


name: dimethylamine + H(+) + H2O + oxidized [electron-transfer flavoprotein] => formaldehyde + methylamine + reduced [electron-transfer flavoprotein]


name: "(R)-2-hydroxyacyl-CoA dehydratase activating ATPase"


name: hexadecanoyl-[ACP] + NADP(+) => (2E)-hexadecenoyl-[ACP] + H(+) + NADPH


name: (3S)-hydroxytetradecanoate + CoA + H(+) => (3S)-hydroxytetradecanoyl-CoA + H2O


name: (1R)-(2-amino-1-hydroxyethyl)phosphonate + CO2 + succinate => (2-aminoethyl)phosphonate + 2-oxoglutarate + O2


name: SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)


name: (S)-malate + 1-O-(trans-sinapoyl)-beta-D-glucose => D-glucose + sinapoyl (S)-malate


name: DCN (decorin) degradation by MMP14 (Mus musculus)


name: ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate + H2O => acetate + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+)


name: Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)


name: TXLNA (IL14) binds syntaxin3 (Canis familiaris)


name: 2-oxobutanoate + acetyl-CoA + H2O => (R)-2-ethylmalate + CoA + H(+)


name: (6Z)-octadecenamide + H2O <=> (6Z)-octadecenoate + NH4(+)


name: ATP + beta-nicotinamide D-riboside = ADP + beta-nicotinamide D-ribonucleotide + H(+)


name: ABCE1 binds RNASEL, inhibiting it (Rattus norvegicus)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Homo sapiens)


name: NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Gallus gallus)


name: 7-dehydrocholesterol + A + H2O <=> AH2 + cholesta-5,7-dien-3beta,25-diol


name: 2 H(+) + H2O + oleanolate + oxidized [NADPH--hemoprotein reductase] => O2 + oleanolic aldehyde + reduced [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + a methylated nucleobase within DNA + O2 => a nucleobase within DNA + CO2 + formaldehyde + succinate


name: GHRH receptor binds GHRH (Canis familiaris)


name: [Pyr1]apelin-13 + H2O = [Pyr1]apelin-12 + L-phenylalanine


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Homo sapiens)


name: STON2 is neddylated (Schizosaccharomyces pombe)


name: formyl-CoA + oxalate => formate + oxalyl-CoA


name: 6-deoxotyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + typhasterol


name: a fatty acid + ethanolamine => an N-acylethanolamine + H2O


name: 1alpha,25-dihydroxyvitamin D2 + H2O + 2 oxidized [adrenodoxin] => 25-hydroxyvitamin D2 + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: acetaldehyde + H2O + NAD(+) <=> acetate + 2 H(+) + NADH


name: Decitabine triphosphate incorporates into DNA (Homo sapiens)


name: an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => an organic molecule + O2 + reduced [NADPH--hemoprotein reductase]


name: CARKD dehydrates S-NAD(P)HX to NADPH (Schizosaccharomyces pombe)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Canis familiaris)


name: Phosphorylation of TSC2 by PKB (Sus scrofa)


name: glucose dehydrogenase (FAD, quinone) activity


name: The PIDDosome binds CASP2 (Mus musculus)


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Sus scrofa)


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: L-isoleucine(out) + Na(+)(out) => L-isoleucine(in) + Na(+)(in)


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-galctosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: CDH11 associates with catenins (Homo sapiens)


name: 6-azauridine + ATP <=> 6-azauridine 5'-phosphate + ADP + H(+)


name: (1S,2S)-OPC-8 + ATP + CoA => AMP + diphosphate + OPC8-CoA


name: Activation of Ca2+ activated Potassium channels with small conductance (Drosophila melanogaster)


name: NUDT12 hydrolyses NADH to NMNH (Dictyostelium discoideum)


name: ADP-D-ribose + H2O = AMP + D-ribose 5-phosphate + 2 H(+)


name: GSTZ1 isomerizes 4-MAA (Dictyostelium discoideum)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Drosophila melanogaster)


name: 5-aminopentanamide + H2O = 5-aminopentanoate + NH4(+)


name: Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)


name: stevioside + UDP-alpha-D-glucose => H(+) + rebaudioside A + UDP


name: dimethylallyl diphosphate + neoechinulin A = diphosphate + isoechinulin A


name: Phosphorylated FOXO1A is excluded from the nucleus (Caenorhabditis elegans)


name: an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine => an N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Rattus norvegicus)


name: an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + GDP-alpha-D-mannose => GDP + H(+) + mannosylinositol phosphorylphytoceramide


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Dictyostelium discoideum)


name: TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) (Homo sapiens)


name: 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H(+) + 2 H2O => 2 naphthalene-1,2,4,8-tetrol + O2


name: 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate = 16alpha,17alpha-estriol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Schizosaccharomyces pombe)


name: 1-acyl LPC is acylated to PC by LPCAT (Drosophila melanogaster)


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Drosophila melanogaster)


name: eNoSC deacetylates histone H3 (Bos taurus)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Drosophila melanogaster)


name: ADP(in) + dATP(out) => ADP(out) + dATP(in)


name: The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Sus scrofa)


name: a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O <=> a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate


name: 2 sucrose <=> 1(F)-beta-D-fructosylsucrose + D-glucose


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+) <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 = 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate


name: CERK phosphorylates CERA to form C1P (Canis familiaris)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] => (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DLST transfers glutaryl to CoA (Dictyostelium discoideum)


name: RP2 activates the GTPase activity of ARL3 (Mus musculus)


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Homo sapiens)


name: ADA catalyzes the deamination of (deoxy)adenosine (Xenopus tropicalis)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: USP19 deubiquitinates RNF123 (Sus scrofa)


name: CES1,CES2 hydrolyze ASA- to ST (Drosophila melanogaster)


name: PGC2 is isomerised to PGB2 (Homo sapiens)


name: LRRC16A binds F-actin capping protein (Homo sapiens)


name: H(+)(out) + sucrose(out) = H(+)(in) + sucrose(in)


name: SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Bos taurus)


name: H2O2 oxidises ferrohemoglobin to MetHb (Rattus norvegicus)


name: COP9 and TOR1 deneddylate STON2 (Danio rerio)


name: 2-oxoglutarate + L-proline + O2 = CO2 + succinate + trans-4-hydroxy-L-proline


name: The receptor:G-protein complex  binds GTP (Caenorhabditis elegans)


name: Interleukin-23 binds interleukin-23 receptor (Sus scrofa)


name: 14-3-3-zeta binds Raf1 (Drosophila melanogaster)


name: 2 a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycero-3-phospho-1D-myo-inositol


name: acetyl-CoA + 2 H(+) + 3 malonyl-CoA => 3 CO2 + 4 CoA + orsellinate


name: Active FLT3 binds to SLA2 (Canis familiaris)


name: Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus (Homo sapiens)


name: a ganglioside GM2 + UDP-alpha-D-galactose => a ganglioside GM1 + H(+) + UDP


name: p-S407,Y641-STAT6 is dimerized (Bos taurus)


name: acetyl-CoA + chloramphenicol => chloramphenicol 3-acetate + CoA


name: uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid (Bos taurus)


name: Defective TRAF3 does not transmit the signal (Homo sapiens)


name: a ganglioside GM3 + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GD3 + CMP + H(+)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] (Caenorhabditis elegans)


name: Arachidonic acid is oxidised to 12R-HpETE by ALOX12B (Dictyostelium discoideum)


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Sus scrofa)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 => 5,10-methylenetetrahydromethanopterin + H(+)


name: L-cysteinyl-[protein] + S-nitroso-CoA => CoA + S-nitroso-L-cysteinyl-[protein]


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Mus musculus)


name: Somatostatin receptors bind somatostatin and cortistatin (Canis familiaris)


name: H(+) + L-arabinose + NADPH => L-arabinitol + NADP(+)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Plasmodium falciparum)


name: EP300 is recruited to MYC and BCL2 genes (Xenopus tropicalis)


name: N(7)-methylguanosine(1405) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(1405) in 16S rRNA + S-adenosyl-L-methionine


name: [DsbB protein]-dithiol + a quinone <=> [DsbB protein]-disulfide + a quinol


name: L-arabinitol + NAD(+) <=> H(+) + L-xylulose + NADH


name: ATP + H2O + L-valine(out) => ADP + H(+) + L-valine(in) + phosphate


name: ADP and Pi bind to ATPase (Mus musculus)


name: ATP + L-seryl-[acetyl-CoA carboxylase] <=> ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase]


name: MECOM (EVI1) binds the PTEN gene promoter (Homo sapiens)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate => (S)-3-methyl-2-oxopentanoate + H2O


name: (indol-3-yl)acetate + H(+) = CO2 + skatole


name: ESR1 binds ESR1 agonists (Gallus gallus)


name: NAGLU hydrolyses heparan chain(2) (Caenorhabditis elegans)


name: 9,9'-di-cis-zeta-carotene + 2 a quinone => 7,7',9,9'-tetra-cis-lycopene + 2 a quinol


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Rattus norvegicus)


name: trans-Golgi Network Vesicle Scission (Gallus gallus)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Danio rerio)


name: (2E)-hexadecenoyl-CoA + H2O => (3S)-hydroxyhexadecanoyl-CoA


name: phosphate(out) + sn-glycerol 3-phosphate(in) = phosphate(in) + sn-glycerol 3-phosphate(out)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Drosophila melanogaster)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Drosophila melanogaster)


name: ORC1 translocates to the nucleus (Canis familiaris)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Bos taurus)


name: PRKAA2 phosphorylates nuclear NFE2L2 (Bos taurus)


name: B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain (Sus scrofa)


name: PLK1 phosphorylates GORASP1 (Rattus norvegicus)


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Mus musculus)


name: FLIP(S) and procaspase-8 form heterodimer (Canis familiaris)


name: Recruitment of VAV to p-SLP-76 (Xenopus tropicalis)


name: a (3R)-3-isocyanyl-fatty acid + ATP + H(+) => a (3R)-3-isocyanyl-fatty acyl-AMP + diphosphate


name: p-Y348-SYK dissociates (Xenopus tropicalis)


name: oxidative phosphorylation uncoupler activity


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b (Rattus norvegicus)


name: Keratin type I/type II heterodimers form tetramers (Bos taurus)


name: UBA1 adenylates ubiquitin in the cytosol (Canis familiaris)


name: 1,7-dimethylxanthine + S-adenosyl-L-methionine => caffeine + H(+) + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + an alkane-alpha,omega-diamine <=> an omega-aminoaldehyde + L-glutamate


name: 3-chlorocatechol + O2 <=> (2E,4Z)-2-chloromuconate + 2 H(+)


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Caenorhabditis elegans)


name: holo-[ACP] + tetradecanoyl-AMP => AMP + H(+) + tetradecanoyl-[ACP]


name: RHOC translocates to the endoplasmic reticulum membrane (Saccharomyces cerevisiae)


name: D-mannitol + 2 Fe(III)-[cytochrome c] <=> D-fructose + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: butanal + CO2 + H(+) + succinate + sulfate => 2-oxoglutarate + butyl sulfate + O2


name: a ganglioside GM3 (d18:1(4E)) + H2O <=> a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetylneuraminate


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: FLVCR1-1 transports heme from cytosol to extracellular region (Homo sapiens)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Rattus norvegicus)


name: estrone 3-sulfate(in) + succinate(out) => estrone 3-sulfate(out) + succinate(in)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-adenosine) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: carbamoyl phosphate + oxamate = N-carbamoyl-2-oxoglycine + phosphate


name: 4-phospho-D-erythronate + NAD(+) => 3-dehydro-4-O-phospho-D-erythronate + H(+) + NADH


name: ITGA4:ITGB1 binds natalizumab (Canis familiaris)


name: beta-D-galactosyl-(1<->1)-sphing-4-enine + H2O <=> D-galactose + sphing-4-enine


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-oxononanoate + H(+)


name: (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA + H(+) + NADPH = (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+)


name: choline + H2O + 2 O2 <=> glycine betaine + H(+) + 2 H2O2


name: SIRT4 transfers ADPRib to GLUD (Danio rerio)


name: 2-phenylacetaldehyde + H(+) + NADH = 2-phenylethanol + NAD(+)


name: H2O + NAD(+) + nitrous oxide => H(+) + NADH + 2 nitric oxide


name: Detection of damage during initiation of DNA synthesis in S-phase (Saccharomyces cerevisiae)


name: H(+) + tropate + tropine => atropine + H2O


name: Pol II elongation complex moves on the template as transcript elongates (Drosophila melanogaster)


name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Dictyostelium discoideum)


name: GCHFR binds to GCH1 and negatively regulates its activity (Caenorhabditis elegans)


name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Homo sapiens)


name: cyclo(L-phenylalanyl-L-leucyl) + 2 O2 = albonoursin + 2 H2O2


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA => 1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: N-WASP binds ARP2/3 and G-actin (Sus scrofa)


name: FUT2 transfers Fuc to LeX to form LeY (Mus musculus)


name: L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: H(+)(out) + L-galactonate(out) => H(+)(in) + L-galactonate(in)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Homo sapiens)


name: a ribonucleoside 3'-phosphate + H2O <=> a ribonucleoside + phosphate


name: a 1,2-saturated acyl-CoA + an acyl-CoA + H2O <=> an (R)-2-alkyl-3-oxoalkanoate + 2 CoA + H(+)


name: A + D-arginine + H2O <=> 5-guanidino-2-oxopentanoate + AH2 + NH4(+)


name: Interaction of Tie2 with Ang2 (Canis familiaris)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Caenorhabditis elegans)


name: Neuroglobin:oxygen dissociates (Rattus norvegicus)


name: (E)-coniferyl acetate + CoA => (E)-coniferol + acetyl-CoA


name: DENND4s exchange GTP for GDP on RAB10 (Sus scrofa)


name: SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Drosophila melanogaster)


name: anthranilate + ATP + H(+) <=> 2-aminobenzoyl-AMP + diphosphate


name: H(+) + menadione + NADPH <=> menadiol + NADP(+)


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Canis familiaris)


name: methionine adenosyltransferase regulator activity


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Homo sapiens)


name: (3S)-3-hydroxypentanoyl-CoA + H2O <=> (3S)-3-hydroxypentanoate + CoA + H(+)


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)


name: an L-amino acid tripeptide(in) + H(+)(in) => an L-amino acid tripeptide(out) + H(+)(out)


name: Unwinding DNA for the nascent transcript (Schizosaccharomyces pombe)


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Xenopus tropicalis)


name: 2-methylpropan-1-amine + H2O + NADP(+) <=> 2-methylpropanal + H(+) + NADPH + NH4(+)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CTP + H(+) => 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Plasmodium falciparum)


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Drosophila melanogaster)


name: SLC50A1 transports Glc from cytosol to extracellular region (Plasmodium falciparum)


name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Homo sapiens)


name: LIG1 binds APEX1 and PCNA at SSB (Drosophila melanogaster)


name: CYP27A1 27-hydroxylates CHOL (Rattus norvegicus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O


name: (2S)-3-sulfopropanediol <=> 3-oxopropane-1-sulfonate + H2O


name: CoA + glutarate + H(+) => glutaryl-CoA + H2O


name: (2E,6E)-farnesyl diphosphate + 2 H2O => 7-epi-ent-eudesmane-5,11-diol + diphosphate


name: GSTO dimers reduce DeHA to AscH- (Homo sapiens)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Drosophila melanogaster)


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Mus musculus)


name: hexadecane-1,16-diol + O2 <=> H2O2 + hydroxyhexadecanal


name: (2S,3R)-3-methyl-L-aspartate = mesaconate + NH4(+)


name: 2 Fe(III)-[cytochrome c] + H2O + nitrous oxide = 2 Fe(II)-[cytochrome c] + 2 H(+) + 2 nitric oxide


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Rattus norvegicus)


name: (E)-3-(indol-3-yl)acryloyl-CoA + H2O => (R)-3-(indol-3-yl)lactoyl-CoA


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: dihydrocurcumin + H(+) + NADPH => NADP(+) + tetrahydrocurcumin


name: GLP1R binds GLP1R agonists (Canis familiaris)


name: NEIL1 cleaves FapyG from damaged DNA (Homo sapiens)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Homo sapiens)


name: TRAF6 oligomer autoubiquitinates (Sus scrofa)


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Canis familiaris)


name: INPP5E translocates to the primary cilium (Mus musculus)


name: MTTP lipidates APOB-100, forming a pre-VLDL (Canis familiaris)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Canis familiaris)


name: Proteasome proteolyzes ub-HIF-alpha (Mus musculus)


name: (S)-malate(out) + 3 Na(+)(out) => (S)-malate(in) + 3 Na(+)(in)


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Bos taurus)


name: acetyl-CoA + 6 H(+) + 6 malonyl-CoA <=> 6 CO2 + 7 CoA + 2 H2O + nor-toralactone


name: FDPS dimer transfers IPPP to DMAPP (Caenorhabditis elegans)


name: Fe(III)-{di[N-(2,3-dihydroxybenzoyl)-L-seryl]-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + H(+) + H2O = Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + N-(2,3-dihydroxybenzoyl)-L-serine


name: CRAC translocates calcium from the extracellular region to the cytosol (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + O2 => (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: Gamma-secretase cleaves YBX1:NOTCH3 (Gallus gallus)


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Homo sapiens)


name: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate => 5-methylsulfanyl-2,3-dioxopentyl phosphate


name: H(+) + H2O + N-(20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] => N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase]


name: 3-oxo-3-ureidopropanoate + H2O = H(+) + malonate + urea


name: (-)-lariciresinol + NADP(+) <=> (-)-pinoresinol + H(+) + NADPH


name: Inhibin-A binding to TGFBR3 (Xenopus tropicalis)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Drosophila melanogaster)


name: PANK4 hydrolyzes PPANT to pantetheine (Canis familiaris)


name: ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate


name: BMP2 binds to the receptor complex (Rattus norvegicus)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Danio rerio)


name: CHMP7 binds LEMD2 (Saccharomyces cerevisiae)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Bos taurus)


name: RHOBTB3 hydrolyzes ATP (Rattus norvegicus)


name: 7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH


name: Aquaporins passively transport glycerol into cells (Xenopus tropicalis)


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Gallus gallus)


name: (+)-beta-chamigrene + diphosphate => (2E,6E)-farnesyl diphosphate


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-glucose => a 1,2-diacyl-3-O-[beta-D-glucopyranosyl-(1->6)-beta-D-galactopyranosyl]-sn-glycerol + H(+) + UDP


name: coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]-[ferredoxin]


name: acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate (Mycobacterium tuberculosis)


name: type 2 metabotropic GABA receptor binding


name: HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 (Gallus gallus)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Plasmodium falciparum)


name: PP5 dephosphorylates RAF1 S338 (Drosophila melanogaster)


name: (2R,3R)-2,3-dihydrogossypetin + H2O + NAD(+) => (2R,3R)-dihydroquercetin + H(+) + NADH + O2


name: a (2E,4Z)-dienoyl-CoA + H(+) + NADPH => a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)


name: a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O => a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione


name: (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + CO2 + succinate => 2-oxoglutarate + L-asparaginyl-[ankyrin-repeat domain protein] + O2


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol (Dictyostelium discoideum)


name: 2-oxoglutarate + L-lysyl-[collagen] + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + CO2 + succinate


name: RAS proteins are depalmitoylated (Rattus norvegicus)


name: UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Canis familiaris)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Rattus norvegicus)


name: Edg-6 sphingosine 1-phosphate receptor binding


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Bos taurus)


name: Abortive HIV-1 initiation after formation of the first phosphodiester bond (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine <=> 2-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: GNLY is transferred to the phagosome (Homo sapiens)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Mus musculus)


name: eNOS:Caveolin-1 complex binds to Nostrin (Rattus norvegicus)


name: dodecanoyl-CoA + sn-glycerol 3-phosphate = 1-dodecanoyl-sn-glycerol 3-phosphate + CoA


name: (1R,4S)-isodihydrocarvone + A <=> (S)-carvone + AH2


name: Formation of allysine by LOX (Danio rerio)


name: PTPRF, PTPRS, PTPRD bind Liprins (Sus scrofa)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Danio rerio)


name: H(+) + hexadecanoate + NADPH + O2 <=> 14-hydroxyhexadecanoate + H2O + NADP(+)


name: 2-carboxyhexacosanoyl-CoA + ADP + H(+) + phosphate => ATP + hexacosanoyl-CoA + hydrogencarbonate


name: 3-amino-4-hydroxybenzaldehyde + acetyl-CoA = 3-acetylamino-4-hydroxybenzaldehyde + CoA + H(+)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Caenorhabditis elegans)


name: RAR:RXR binds SUMO-CRABP2:atRA (Bos taurus)


name: Translocation of Vav1 to CD28 (Sus scrofa)


name: IL1R1:IL1:IL1RAP binds MYD88 homodimer (Homo sapiens)


name: HMOX1 dimer, HMOX2 cleave heme (Danio rerio)


name: CDC42 and PIP2 bind WASL, activating it (Canis familiaris)


name: H(+) + sulfate + thiosulfate => H2O + trithionate


name: CLCN7:OSTM1 exchanges Cl- for H+ (Xenopus tropicalis)


name: AMP + diphosphate + L-prolyl-tRNA(Pro) => ATP + L-proline + tRNA(Pro)


name: CBL-mediated ubiquitination of CIN85 (Gallus gallus)


name: a 5'-end ribonucleotide-tRNA(His) + ATP + H(+) = a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate


name: 3-oxo-5,6-didehydrosuberyl-CoA + CoA => 2,3-didehydroadipoyl-CoA + acetyl-CoA


name: AMP + deoxycholoyl-CoA + diphosphate => ATP + CoA + deoxycholate


name: (25S)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25S)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Translocation of Cdc25 to the nucleus (Homo sapiens)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Xenopus tropicalis)


name: 2,5-dihydroxybenzoyl-CoA + H2O = 2,5-dihydroxybenzoate + CoA + H(+)


name: A + ethylbenzene + H2O <=> (S)-1-phenylethanol + AH2


name: DAG activation of TRPC channels (Bos taurus)


name: Nitrite ion and HNO2 form a conjugated acid-base pair (Homo sapiens)


name: MAF1 translocates to the nucleus (Danio rerio)


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Gallus gallus)


name: trans-Golgi Network Coat Assembly (Canis familiaris)


name: 2 cob(I)inamide-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein] => 2 cob(II)inamide-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein]


name: NEIL1,NEIL2 recruits POLB to incised AP site (Homo sapiens)


name: 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 27 H(+) + 9 malonyl-CoA + 18 NADPH <=> 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate synthase] + 9 CO2 + 9 CoA + 9 H2O + 18 NADP(+)


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Mus musculus)


name: KIAA0101 double monoubiquitination (Rattus norvegicus)


name: botF:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Canis familiaris)


name: PIKE-L interaction with UNC5B (Homo sapiens)


name: ATP + H2O + pheophorbide a(in) <=> ADP + H(+) + pheophorbide a(out) + phosphate


name: (R)-noradrenaline(out) + 2 H(+)(in) => (R)-noradrenaline(in) + 2 H(+)(out)


name: COX15 transforms heme O to heme A (Bos taurus)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Rattus norvegicus)


name: RAC2 translocates to the ER membrane (Drosophila melanogaster)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Xenopus tropicalis)


name: cephalosporin C + H2O <=> acetate + deacetylcephalosporin C + H(+)


name: Cleaved fibrinogen products bind TLR4:LY96 (Rattus norvegicus)


name: 6 H(+) + hexanoyl-[ACP] + 7 malonyl-CoA => 7 CO2 + 7 CoA + 2 H2O + holo-[ACP] + noranthrone


name: 3-(3-hydroxyphenyl)-propanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 3,3',5-trihydroxybibenzyl + 4 CO2 + 4 CoA


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Danio rerio)


name: a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GP1calpha (d18:1(4E)) + CMP + H(+)


name: coenzyme M + methyl-Co(III)-[glycine betaine-specific corrinoid protein] <=> Co(I)-[glycine betaine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: 4-aminobutanoate(in) + L-glutamate(out) => 4-aminobutanoate(out) + L-glutamate(in)


name: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester => adenosine 3',5'-bisphosphate + H(+) + L-tyrosine methyl ester 4-sulfate


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + H2O <=> 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H(+) + octadecanoate


name: IL36:IL1RL2 binds IL1RAP-1 (Xenopus tropicalis)


name: H2O + 2 monodehydro-L-ascorbate radical + N-dodecanoyl-(2S)-hydroxyglycine => 2 L-ascorbate + N-dodecanoylglycine + O2


name: H(+) + N(6)-(dimethylallyl)adenosine 5'-triphosphate + NADPH + O2 = 9-ribosyl-trans-zeatin 5'-triphosphate + H2O + NADP(+)