name: formaldehyde + L-alanine => 2-methyl-L-serine


name: PEX19:class I PMP binds PEX3 (Danio rerio)


name: NCOA1 recruits EP300 to the ABCA1 promoter (Drosophila melanogaster)


name: H(+) + H2O + L-tyrosine + O2 <=> (4-hydroxyphenyl)acetaldehyde + CO2 + H2O2 + NH4(+)


name: 2 Na(+)(in) + taurocholate(in) => 2 Na(+)(out) + taurocholate(out)


name: GSTK1 dimer transfers GS from GSH to CDNB (Homo sapiens)


name: DARPP-32 is dephosphorylated on Thr75 by PP2A (Rattus norvegicus)


name: PKA phosphorylates RET:GDNF:GFRA dimer (Sus scrofa)


name: acetyl-CoA + N-terminal L-methionyl-L-leucyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein]


name: S-adenosyl-L-methionine + uridine(341) in tmRNA => 5-methyluridine(341) in tmRNA + H(+) + S-adenosyl-L-homocysteine


name: 3,4-dihydroxyphenylacetate + H(+) = 4-methylcatechol + CO2


name: HDAC8 deacetylates histones (Saccharomyces cerevisiae)


name: Interaction of E3 ligase with ISG15:E2 complex (Mus musculus)


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Caenorhabditis elegans)


name: hydrogen sulfide + O-succinyl-L-serine => L-cysteine + succinate


name: Association of procollagen type II (Homo sapiens)


name: ADAM10:Zn2+:TSPANs translocates from ER lumen to plasma membrane (Homo sapiens)


name: CO2 + formaldehyde + neopinone + succinate => 2-oxoglutarate + O2 + thebaine


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Bos taurus)


name: Alpha-defensin dimers multimerize to form a pore complex (Homo sapiens)


name: 4 AH2 + all-trans-lycopene => 15-cis-phytoene + 4 A


name: 1-O-alkyl-sn-glycerol + phosphate => 1-O-alkyl-sn-glycero-3-phosphate + H2O


name: Activation of EPACs by cAMP (Gallus gallus)


name: SMG6 hydrolyzes mRNA with premature termination codon (Sus scrofa)


name: calcidiol + UDP-alpha-D-glucuronate = calcidiol 3-O-(beta-D-glucuronide) + H(+) + UDP


name: Ferriheme is transferred from Albumin to Hemopexin (Xenopus tropicalis)


name: MTTP binds lomitapide (Canis familiaris)


name: adenosine 5'-phosphosulfate + ATP => 3'-phosphoadenylyl sulfate + ADP + H(+)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol => 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA


name: dodecapentaneoyl-[polyketide synthase] + fumagillol => holo-[polyketide synthase] + prefumagillin


name: an alpha-L-fucoside + H2O = an alcohol + L-fucose


name: biphenyl + H(+) + NADH + O2 => (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphocholine


name: ub UBXN7 is degraded by the 26S proteasome (Homo sapiens)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Rattus norvegicus)


name: a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase] <=> a 21-hydroxy-C21-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Caenorhabditis elegans)


name: 13-cis-retinol + a fatty acyl-CoA <=> 13-cis-retinyl ester + CoA


name: 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + NAD(+) => 2,5-dichlorohydroquinone + H(+) + NADH


name: Autophosphorylation of KIT (Rattus norvegicus)


name: (indol-3-yl)acetate(out) + a dicarboxylate(in) => (indol-3-yl)acetate(in) + a dicarboxylate(out)


name: beta-himachalene + diphosphate => (2E,6E)-farnesyl diphosphate


name: diphosphate + ilicicolinate B => (2E,6E)-farnesyl diphosphate + orsellinate


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Bos taurus)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Homo sapiens)


name: H2O + Xaa-L-Pro dipeptide <=> an L-alpha-amino acid + L-proline


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Xenopus tropicalis)


name: 2 dinapinone A + 2 H2O => 4 monapinone A + O2


name: IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Bos taurus)


name: Formation of lysyl-pyridinoline cross-links (Rattus norvegicus)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Danio rerio)


name: L-threonate + NAD(+) = 2-dehydro-L-erythronate + H(+) + NADH


name: Factor H binds to membrane-associated C3b (Homo sapiens)


name: Connexin synthesis (generic) (Xenopus tropicalis)


name: Initial activation of proMMP1 (Gallus gallus)


name: cya and lef bind to pagA(197-794):ANTXR2 oligomer (Homo sapiens)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Homo sapiens)


name: isorhamnetin + S-adenosyl-L-methionine => 3',4'-O-dimethylquercetin + 2 H(+) + S-adenosyl-L-homocysteine


name: SESN1,2 binds L-leucine and dissociates from GATOR2 (Mus musculus)


name: PIAS4 SUMOylates VHL with SUMO1 (Danio rerio)


name: D-glutamine + H2O <=> D-glutamate + NH4(+)


name: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity


name: AMP(in) + diphosphate(in) + H(+)(in) + octadecanoyl-CoA(in) => ATP(in) + CoA(in) + H(+)(out) + octadecanoate(out)


name: Recruitment of TANK to TRAF6 (Homo sapiens)


name: ITGA4:ITGB1 binds natalizumab (Sus scrofa)


name: p-PKR dimer phosphorylates CDK1 (Bos taurus)


name: 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Mus musculus)


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Bos taurus)


name: HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O => 10-epi-juneol + diphosphate


name: 2-phenylacetaldehyde + H(+) + NADH <=> 2-phenylethanol + NAD(+)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Bos taurus)


name: RHOA:GTP binds ROCK, activating it (Bos taurus)


name: Intermediate I binds second heme, UQCRB, UQCRQ (Homo sapiens)


name: Alpha-1-Microglobulin is cleaved (Mus musculus)


name: H2O + N-(acetyl)-sphing-4-enine => acetate + sphing-4-enine


name: 2 H2O2 => O2 + 2 H2O (Saccharomyces cerevisiae)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Bos taurus)


name: a plastoquinone + (n+1) H(+)(in) + NADH <=> a plastoquinol + n H(+)(out) + NAD(+)


name: 15-cis-phytoene + 3 A <=> 3 AH2 + all-trans-neurosporene


name: 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: NTPDase4 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + H2O = 2-O-(alpha-D-glucopyranosyl)glycerol + phosphate


name: Formation of p-STAT1 homodimer (Mus musculus)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Caenorhabditis elegans)


name: 7-carboxy-7-deazaguanine + ATP + NH4(+) => 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate


name: (9Z,12Z)-octadecadienoate + AH2 + O2 = (13S)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA <=> (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H2O


name: 2 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) => 2 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out)


name: H2O + O-phospho-L-threonyl-[myosin light chain] => L-threonyl-[myosin light chain] + phosphate


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Dictyostelium discoideum)


name: CO2 + dATP + H2O => ATP + formate + H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate


name: 6-acetyl-D-glucose + H2O = acetate + D-glucose + H(+)


name: CDC42 and PIP2 bind WASL, activating it (Gallus gallus)


name: (4R)-4-hydroxy-2-oxoglutarate => glyoxylate + pyruvate


name: p-T68-CHEK2 autophosphorylates (Bos taurus)


name: (E)-non-2-enal + H2O + NAD(+) = (E)-non-2-enoate + 2 H(+) + NADH


name: Cleavage and polyadenylation of Intronless Pre-mRNA (Drosophila melanogaster)


name: an aldehyde + 2 Fe(II)-[cytochrome c550] + 2 H(+) + NH4(+) => an aliphatic amine + 2 Fe(III)-[cytochrome c550] + H2O


name: peroxisome matrix targeting signal-1 binding


name: 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Ragulator binds Rag dimers (Gallus gallus)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR2 (Rattus norvegicus)


name: Exocytosis of tertiary granule lumen proteins (Dictyostelium discoideum)


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Rattus norvegicus)


name: Synthesis of PIP3 from PIP2 by PI3K (Mus musculus)


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-GTP <=> GTP + H(+) + lactate


name: H2O + N-succinyl-L-glutamate => L-glutamate + succinate


name: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate


name: H(+)(out) + L-histidine(out) + L-ornithine(in) => H(+)(in) + L-histidine(in) + L-ornithine(out)


name: 3-methylbutanoyl-CoA + S-adenosyl-L-methionine = CoA + H(+) + N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine


name: USP16,USP21 deubiquitinate Histone H2A (Gallus gallus)


name: 2-succinylbenzoate + H2O => (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate


name: 2-aminomalonate semialdehyde + H(+) + NADPH => D-serine + NADP(+)


name: ERK5 translocates to the nucleus (Caenorhabditis elegans)


name: EGFR binds EGF ligand (Canis familiaris)


name: Defective IRAK4 does not form a complex with MyD88 within the TLR5 complex (Homo sapiens)


name: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H(+) + NADH = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Mus musculus)


name: Cytosolic folate export across the plasma membrane (Sus scrofa)


name: (3Z)-2-oxo-4-carboxy-3-hexenedioate + H2O = (2S)-2-hydroxy-4-oxobutane-1,2,4-tricarboxylate


name: H2O + NADP(+) + taurine => H(+) + hypotaurine + NADPH + O2


name: isocholate + NADP(+) => 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Bos taurus)


name: (S)-methylmalonyl-CoA + NADP(+) => acryloyl-CoA + CO2 + NADPH


name: ABHD4 hydrolyses NAPE (Xenopus tropicalis)


name: FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4 (Mus musculus)


name: cannabigerolate + O2 = Delta(9)-tetrahydrocannabinolate + H2O2


name: an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O = a guanosine in RNA + H(+) + lactate


name: cytosine(in) + H(+)(in) => cytosine(out) + H(+)(out)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine => N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: Reduction of presqualene diphosphate to form squalene (Homo sapiens)


name: ATP + H2O + sphing-4-enine 1-phosphate(in) = ADP + H(+) + phosphate + sphing-4-enine 1-phosphate(out)


name: a 1-[(9Z)-octadecenoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 1-octadecanoyl 2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O = a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + sulfate


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Gallus gallus)


name: 3'-phosphoadenylyl sulfate + quercetin 3,3'-bissulfate <=> adenosine 3',5'-bisphosphate + H(+) + quercetin 3,3',7-trissulfate


name: phosphate + propanoyl-CoA = CoA + propanoyl phosphate


name: a sphingoid base + ATP => a sphingoid 1-phosphate + ADP + H(+)


name: Defective CYP27A1 does not 27-hydroxylate 5β-CHOL3α,7α,24(s)-triol (Homo sapiens)


name: (2E)-butenoyl-CoA + CO2 + FADH2 => FAD + glutaryl-CoA + 2 H(+)


name: (2E)-geranyl benzoate + CoA => (2E)-geraniol + benzoyl-CoA


name: p-T774-PKN1 phosphorylates CDC25C (Bos taurus)


name: H2O + IMP <=> D-ribose 5-phosphate + hypoxanthine


name: SORD oxidizes D-sorbitol to Fru (Canis familiaris)


name: Binding of IRS to insulin receptor (Bos taurus)


name: RHOB GAPs stimulate RHOB GTPase activity (Homo sapiens)


name: myo-inositol + S-adenosyl-L-methionine <=> 1D-3-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: Interaction of GRB2:SOS complex with p-SHC1 (Rattus norvegicus)


name: Extracellular processing of novel PDGFs (Xenopus tropicalis)


name: 2'-deoxyguanosine + NAD(+) = H(+) + N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine + nicotinamide


name: Activation of conventional Protein Kinase C (Xenopus tropicalis)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: Formation of eIF2:GDP:eIF2B intermediate (Gallus gallus)


name: Mg-protoporphyrin IX + S-adenosyl-L-methionine => Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine


name: glycyl-L-methionine + H2O = glycine + L-methionine


name: (2E)-geranyl diphosphate = (2R,4S)-bornyl diphosphate


name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter (Homo sapiens)


name: an N-acyl-sphingoid base + UDP-alpha-D-galactose = a D-galactosylceramide + H(+) + UDP


name: (S)-reticuline + 2-oxoglutarate + O2 <=> (S)-6-O-demethylreticuline + CO2 + formaldehyde + succinate


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Bos taurus)


name: glycine + 2 S-adenosyl-L-methionine = 2 H(+) + N,N-dimethylglycine + 2 S-adenosyl-L-homocysteine


name: 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA + S-adenosyl-L-methionine => 5'-deoxyadenosine + archaeosine(15) in tRNA + 2 H(+) + L-1-piperideine-6-carboxylate + L-methionine


name: POM121 and NDC1 bind the Nup93 complex (Mus musculus)


name: 6beta,16alpha,17alpha-trihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 16alpha,17alpha-dihydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase]


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Homo sapiens)


name: Phosphorylation of MEK4 by MEKK1 (Canis familiaris)


name: Factor Xa inhibitors bind Va:Xa (Sus scrofa)


name: Phosphorylation of cPLA2 by ERK-2 (Saccharomyces cerevisiae)


name: NUDT12 hydrolyses NADH to NMNH (Mus musculus)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Danio rerio)


name: EXT1:EXT2 transfers GlcNAc to heparan (Drosophila melanogaster)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Sus scrofa)


name: 2 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: H2O + N-(9Z-octadecenoyl)-L-lysine = (9Z)-octadecenoate + L-lysine


name: 2-oxoglutarate + dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose = dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + L-glutamate


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Homo sapiens)


name: REG3A binds bacterial phospholipids (Drosophila melanogaster)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + ATP + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + ADP + H(+) + phosphate


name: CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Drosophila melanogaster)


name: Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Sus scrofa)


name: 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine => 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + L-serine


name: ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues (Gallus gallus)


name: 5-methyldeoxycytidine 5'-phosphate + ATP => 5-methyldeoxycytidine diphosphate + ADP


name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Xenopus tropicalis)


name: 5-aminomethyl-2-thiouridine(34) in tRNA + S-adenosyl-L-methionine = 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Gallus gallus)


name: GTP + H(+) + phosphoenolpyruvate => diphosphate + enolpyruvoyl-2-diphospho-5'-guanosine


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: H2O + N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine <=> a fatty acid + H(+) + N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Mus musculus)


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Canis familiaris)


name: ligase activity, forming nitrogen-metal bonds


name: 1-hexadecanoyl-2-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = (6Z,9Z,12Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Interaction of Tie2 and Shc1 (Sus scrofa)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Bos taurus)


name: (R)-carnitinyl-CoA + crotonobetaine => (R)-carnitine + crotonobetainyl-CoA


name: Ficolin-1 binds to molecular patterns on the target cell surface (Mus musculus)


name: chorismate + H2O + 2 L-glutamine <=> 4-amino-4-deoxychorismate + 2 L-glutamate + NH4(+)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Sus scrofa)


name: a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine <=> a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + H(+) + UDP


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-corvol ether A + diphosphate


name: Interaction of PECAM-1 and SHIP (Mus musculus)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Canis familiaris)


name: NUDT12 hydrolyses NADH to NMNH (Xenopus tropicalis)


name: 1-octadecanoyl-sn-glycero-3-phosphoserine + H2O = H(+) + octadecanoate + sn-glycero-3-phospho-L-serine


name: Fringe-modified Pre-NOTCH is cleaved by FURIN (Mus musculus)


name: Formation of lysino-5-ketonorleucine cross-links (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate <=> bicyclogermacrene + diphosphate


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Rattus norvegicus)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Danio rerio)


name: SOD2 gene expression is stimulated by FOXO4, FOXO3 and FOXO1 (Homo sapiens)


name: STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Gallus gallus)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Sus scrofa)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Danio rerio)


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Xenopus tropicalis)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Xenopus tropicalis)


name: chloride + H(+) + H2O2 <=> H2O + hypochlorous acid


name: a D-threo-aldose + NAD(+) = a D-threo-aldono-1,5-lactone + H(+) + NADH


name: MDH2 dimer dehydrogenates MAL (Bos taurus)


name: L-phenylalanine + taurocholate => L-phenylalanocholate + taurine


name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Homo sapiens)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Canis familiaris)


name: high-density lipoprotein particle receptor binding


name: Lsm1-7 Complex binds deadenylated mRNA (Schizosaccharomyces pombe)


name: PELI1 ubiquitinates RIPK3 at K363 (Bos taurus)


name: CTP + D-ribulose 5-phosphate + H(+) = CDP-D-ribulose + diphosphate


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Mus musculus)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Sus scrofa)


name: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Rattus norvegicus)


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Gallus gallus)


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Caenorhabditis elegans)


name: an N-acyl-aromatic L-alpha-amino acid + H2O <=> a carboxylate + an aromatic L-alpha-amino acid


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Saccharomyces cerevisiae)


name: Homodimerization of VEGF proteins (Xenopus tropicalis)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Sus scrofa)


name: Ribosomal scanning  (Saccharomyces cerevisiae)


name: ITGBL1 gene expression is stimulated by RUNX2 (Homo sapiens)


name: [DsrC protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide = [DsrC protein]-dithiol + 2 AH2 + H(+) + sulfite


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Drosophila melanogaster)


name: PEX19:class I PMP binds PEX3 (Drosophila melanogaster)


name: CysS248-MPST:TXN2 dissociates (Danio rerio)


name: GSK3B phosphorylates p-NFE2L2 (Homo sapiens)


name: 4-nitrophenyl-3-ketovalidamine => 4-nitroaniline + 5D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one


name: Activation of proMMP9 by proteases (Bos taurus)


name: L-arginine(out) + N(omega)-methyl-L-arginine(in) <=> L-arginine(in) + N(omega)-methyl-L-arginine(out)


name: CLEC10A binds Tn-MUC1 (Caenorhabditis elegans)


name: Translocation of PTK2 to Focal complexes (Bos taurus)


name: Active PLCG1 hydrolyses PIP2 (Homo sapiens)


name: Hikeshi binds HSP70s:ATP (Xenopus tropicalis)


name: 1-O-alkyl-2-acyl-sn-glycerol + CDP-choline => 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA => (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O


name: H2O + NAD(+) + spermine monoaldehyde => 2 H(+) + N-(2-carboxyethyl)spermidine + NADH


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Sus scrofa)


name: ABCC5 transports TPMP substrates from cytosol to extracellular region (Bos taurus)


name: (2Z,6Z)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + nerylneryl diphosphate


name: (2S,4R)-ketoconazole(in) + ATP + H2O => (2S,4R)-ketoconazole(out) + ADP + H(+) + phosphate


name: ARSA removes sulfate from PSAP(195-273):Sulfatide (Canis familiaris)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Drosophila melanogaster)


name: PC is transphosphatidylated to PG by PLD1-4/6 (Homo sapiens)


name: N-(8'-oxogeranyl)-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase]


name: H(+)(in) + L-glutamine(out) + Na(+)(out) <=> H(+)(out) + L-glutamine(in) + Na(+)(in)


name: Defective ALG8 does not add glucose to the N-glycan precursor (Homo sapiens)


name: ATP + CoA + thiophene-2-carboxylate <=> AMP + diphosphate + thiophene-2-carbonyl-CoA


name: Deubiquitinated PTEN translocates to the cytosol (Homo sapiens)


name: ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)


name: Na+/H+ exchanger transport (at cell membrane) (Danio rerio)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Mus musculus)


name: L-thyroxine sulfate(in) => L-thyroxine sulfate(out)


name: H2O + L-selenocystathionine <=> 2-oxobutanoate + L-selenocysteine + NH4(+)


name: D-galactono-1,4-lactone + H2O = D-galactonate + H(+)


name: RAS proteins are depalmitoylated (Homo sapiens)


name: SUMOylation of ING2 with SUMO1 (Mus musculus)


name: (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H(+) + NADPH => (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: ATP + L-glutamate + tRNA(Glu) <=> AMP + diphosphate + L-glutamyl-tRNA(Glu)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Xenopus tropicalis)


name: 3'-phosphoadenylyl sulfate + glycocholate <=> adenosine 3',5'-bisphosphate + glycocholate 7-sulfate + H(+)


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Gallus gallus)


name: amicoumacin A 2-phosphate + H2O => amicoumacin A + phosphate


name: nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Homo sapiens)


name: AUF1 (hnRNP D0) is ubiquitinylated (Bos taurus)


name: Part of the ICD migrates to the nucleus (Canis familiaris)


name: SMAC (DIABLO) forms dimer (Xenopus tropicalis)


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Homo sapiens)


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + phosphate <=> alpha-D-galactose 1-phosphate + N-acetyl-D-glucosamine


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: PRMT1 methylates ESRs (Xenopus tropicalis)


name: L-serine + pyruvate <=> 3-hydroxypyruvate + L-alanine


name: SEC24A,B:SEC23A bind SEC22B (Plasmodium falciparum)


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Canis familiaris)


name: arginine + glycine => ornithine + guanidoacetate (Mus musculus)


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Homo sapiens)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Caenorhabditis elegans)


name: a neolactoside IV(3)-alpha-Gal,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+) => alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP-beta-L-fucose


name: L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] => H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Caenorhabditis elegans)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: PK binds to VANG at the plasma membrane (Drosophila melanogaster)


name: an N-acyl-D-amino acid + H2O => a carboxylate + a D-alpha-amino acid


name: MAFA-, NKX2-2-, PAX6-, and PDX1-dependent synthesis of insulin precursor protein (Homo sapiens)


name: 3-oxochol-4-en-22-oyl-CoA + NAD(+) = 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH


name: PEX19 binds class I peroxisomal membrane proteins (Schizosaccharomyces pombe)


name: (R)-lactate + ATP + D-alanine = ADP + D-alanyl-(R)-lactate + phosphate


name: (8aS)-octahydroindolizin-1-one + CO2 + CoA + 2 H2O + 2 NADP(+) => 4 H(+) + L-pipecolate + malonyl-CoA + 2 NADPH


name: Activation of SHP2 through the binding to phospho-Gab1 (Homo sapiens)


name: (3R)-3-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylate + diphosphate + H(+) => (2E,6E)-farnesyl diphosphate + 3,5-dimethylorsellinate


name: Mis18 complex binds the centromere (Gallus gallus)


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Rattus norvegicus)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Danio rerio)


name: Translocation of caspase-3 to the nucleus (Gallus gallus)


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Mus musculus)


name: N-[omega-(9Z,12Z)-octadecadienoyloxy]-acylsphin-4-enine + O2 => N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine


name: 2-phenylacetaldehyde + CO2 => 3-phenylpyruvate + H(+)


name: (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + tetradecanoyl-[ACP] <=> ((9Z)-hexadecenoyl-tetradecanoyl)-(Kdo)2-lipid A + holo-[ACP]


name: [phosphate](n-1) + H(+) + phosphate => [phosphate](n) + H2O


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Homo sapiens)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Homo sapiens)


name: CYP11B2 oxidises 11DCORST to CORST (Sus scrofa)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Sus scrofa)


name: 1,2-dihexadecanoyl-sn-glycero-3-CDP + myo-inositol = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)


name: H(+) + O-phospho-L-threonine <=> (R)-1-aminopropan-2-yl phosphate + CO2


name: 19-hydroxy-11-deoxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 19-oxo-11-deoxycorticosterone + 2 H2O + 2 oxidized [adrenodoxin]


name: (E)-caffeoyl-CoA + H2O <=> 3,4-dihydroxybenzaldehyde + acetyl-CoA


name: AMP + diphosphate + H(+) + N(8),N'(8)-citryl-bis(spermidine) => ATP + N(8)-citryl-spermidine + spermidine


name: MCM4, MCM6 and MCM7 form a heterotrimer (Dictyostelium discoideum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol


name: primary active transmembrane transporter activity


name: heparan sulfate 2-O-sulfotransferase activity


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Homo sapiens)


name: APAF1:CYCS binds APIP (Rattus norvegicus)


name: pyruvate + UTP => H(+) + phosphoenolpyruvate + UDP


name: 2-methoxy-6-(all-trans-heptaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine => 3-(all-trans-heptaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine


name: (5S,9S,10S)-drim-7-en-11-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> (5S,10S)-(9R)-7-drimene-11,12-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 2-deoxystreptamine antibiotic + acetyl-CoA => an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)


name: H2O + malonyl-CoA = CoA + H(+) + malonate


name: 3-oxopropanoate + CoA + NADP(+) => acetyl-CoA + CO2 + NADPH


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Homo sapiens)


name: 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Sus scrofa)


name: RAS signaling and prolonged interferon-beta stimulation promote generation of reactive oxygen species (ROS) (Homo sapiens)


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Canis familiaris)


name: (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Sus scrofa)


name: GTP + H2O <=> guanosine + H(+) + triphosphate


name: 2 1-(9Z-octadecenoyl)-glycerol => 1,2-di-(9Z-octadecenoyl)-glycerol + glycerol


name: beta-alanyl-L-lysine + H2O => beta-alanine + L-lysine


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Xenopus tropicalis)


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: G protein-coupled adenosine receptor activity


name: CYP2E1 monooxygenates APAP to NAPQI (Drosophila melanogaster)


name: Depolymerization of lamin filaments after PKC-mediated phosphorylation (Xenopus tropicalis)


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Rattus norvegicus)


name: eicosanoyl-CoA + H2O <=> CoA + eicosanoate + H(+)


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Rattus norvegicus)


name: a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1a (d18:1(4E)) + CMP + H(+)


name: a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GM1alpha + CMP + H(+)


name: FAHD1 dimer hydrolyses OA to PYR (Xenopus tropicalis)


name: NEK6/NEK7 phosphorylates NUP98 (Homo sapiens)


name: an N-acyl-(4R)-4-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + a fatty acid


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 16beta,17beta-estriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)


name: glycolate(in) + H(+)(in) = glycolate(out) + H(+)(out)


name: DEGS1 dehydrogenates dihydroceramide (Xenopus tropicalis)


name: ACSS3 ligates CoA to CH3COO- (Xenopus tropicalis)


name: (5-hydroxyindol-3-yl)acetaldehyde + H2O + NAD(+) = (5-hydroxyindol-3-yl)acetate + 2 H(+) + NADH


name: Kinesin-5 is a homotetramer (Schizosaccharomyces pombe)


name: 2 H(+) + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine => guanosine(26) in tRNA + 2 S-adenosyl-L-methionine


name: FAD + H(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + FADH2


name: 2,2-dihydroxyspheroidene = H2O + spheroiden-2-one


name: GUSB tetramer hydrolyses CS/HS precursor (Sus scrofa)


name: TORC2 (mTOR) phosphorylates AKT at S473 (Schizosaccharomyces pombe)


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Danio rerio)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Gallus gallus)


name: H2O + N-acetylputrescine <=> acetate + putrescine


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Plasmodium falciparum)


name: benzylamine + H2O + O2 <=> benzaldehyde + H2O2 + NH4(+)


name: (3S)-citramalyl-CoA => acetyl-CoA + pyruvate


name: Phosphorylated KHDRBS1 translocates to the cytosol (Sus scrofa)


name: ATP + GTP => diphosphate + pppGp(2'-5')A


name: NAD(+) + sulcatol <=> H(+) + NADH + sulcatone


name: SHP2 interacts with p-KIT (Canis familiaris)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Mus musculus)


name: secondary active cyanate transmembrane transporter activity


name: (2S)-3-sulfolactate + 2 H(+) + NADH => (2S)-3-sulfolactaldehyde + H2O + NAD(+)


name: 15alpha-stemmadenine + NADP(+) => 15alpha-stemmadenine intermediate II + 2 H(+) + NADPH


name: 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose = 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Bos taurus)


name: 5,6-dihydrothymine + H2O = 3-(carbamoylamino)-2-methylpropanoate + H(+)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Drosophila melanogaster)


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: H2O + L-histidinol phosphate = L-histidinol + phosphate


name: kainate selective glutamate receptor activity


name: (2R,3S)-iso(homo)3citrate => cis-(homo)3aconitate + H2O


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose = [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n+1)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Bos taurus)


name: Basigin interacts with CD43 (Sus scrofa)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Schizosaccharomyces pombe)


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Sus scrofa)


name: DNA polymerase epsilon binds at the origin (Dictyostelium discoideum)


name: Initial activation of proMMP13 by plasmin and trypsin (Xenopus tropicalis)


name: [aequorin]--dioxetanone = [excited state blue fluorescent protein] + CO2


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + H(+) <=> 2-GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane


name: Interaction of Tie2 and Dok-2 (Mus musculus)


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine


name: 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 2 AH2 + CO2 => 8-carboxy-8-demethylriboflavin 5'-phosphate + 2 A + H2O + L-glutamate


name: Recruitment of GRB2:SOS to p-5Y-LAT (Canis familiaris)


name: beta-D-glucosyl-(1->4)-D-galactose + phosphate <=> alpha-D-glucose 1-phosphate + D-galactose


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Homo sapiens)


name: 1,6-dihydroxyphenazine N(5)-oxide + H2O + NADP(+) => 1,6-dihydroxyphenazine + NADPH + O2


name: (E)-isoeugenol + S-adenosyl-L-methionine => (E)-isomethyleugenol + H(+) + S-adenosyl-L-homocysteine


name: a 2'-deoxyguanosine in DNA + NAD(+) = an N(2)-(ADP-L-ribosyl)-2'-deoxyguanosine in DNA + H(+) + nicotinamide


name: eicosanoyl-CoA + FAD + H(+) <=> (2E)-eicosenoyl-CoA + FADH2


name: Trafficking of GluR2-containing AMPA receptors to synapse (Bos taurus)


name: Phosphorylation of DCC by Fyn (Bos taurus)


name: 5,6-dihydrothymine + NAD(+) => H(+) + NADH + thymine


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Homo sapiens)


name: Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Mus musculus)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol = (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA


name: [phosphate](n) + UTP => [phosphate](n+1) + UDP


name: glyphosate + H2O + O2 <=> aminomethylphosphonate + glyoxylate + H(+) + H2O2


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Gallus gallus)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Mus musculus)


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Mus musculus)


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Sus scrofa)


name: EGR2 and SOX10 bind the MBP gene (Homo sapiens)


name: 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine => 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: PRC2 trimethylates histone H3 at lysine-27 (Bos taurus)


name: IL37, IL37(?-218) translocates from cytosol to extracellular region (Homo sapiens)


name: Collagen type II degradation by MMP15 (Canis familiaris)


name: p-Y-STATs translocate to nucleus (Mus musculus)


name: H2O + NADP(+) + nitrite => H(+) + NADPH + nitrate


name: PTK6 translocates to the nucleus (Sus scrofa)


name: S1P hydrolyzes SREBP1A,1C,2 (Homo sapiens)


name: Ghrelin O-acyltransferase decanoylates Proghrelin (Canis familiaris)


name: Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Rattus norvegicus)


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Canis familiaris)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = (+)-costunolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-(dihydroxymethyl)-5-formylfuran + O2 = 2-carboxy-5-formylfuran + H(+) + H2O2


name: HMOX1 translocates from the cytosol to the nucleoplasm (Xenopus tropicalis)


name: (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin] => calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Drosophila melanogaster)


name: acetyl-CoA + H2O => acetate + CoASH (Saccharomyces cerevisiae)


name: 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-methionine => 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Canis familiaris)


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] <=> 16alpha-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Sus scrofa)


name: a ubiquinone + D-glucose <=> a ubiquinol + D-glucono-1,5-lactone


name: FYN phosphorylates PAK2 (Caenorhabditis elegans)


name: Raf dimer inhibitors bind RAF heterodimers (Canis familiaris)


name: Phosphorylated GAB1 recruits PI3K to MET (Homo sapiens)


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Rattus norvegicus)


name: DNA polymerase delta polymerizes DNA across single stranded gap (Schizosaccharomyces pombe)


name: 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O => D-glucose + D-glucose 6-phosphate


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Danio rerio)


name: JAK2 is phosphorylated, activated (Homo sapiens)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Bos taurus)


name: Type B histone acetlytransferase complex acetylates histone H4 (Mus musculus)


name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Mus musculus)


name: a cytidine(6-4)thymidine in DNA = a cytidine-thymine dinucleotide in DNA


name: 12,13-epoxy-(9Z)-octadecenoate + H2O => 12,13-dihydroxy-(9Z)-octadecenoate


name: CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphing-(8E)-enine => (4R)-hydroxysphing-(8E)-enine + tetracosanoyl-CoA


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Sus scrofa)


name: PDE3B hydrolyses cAMP to AMP (Rattus norvegicus)


name: 2-dehydro-L-erythronate + H(+) + NADH => L-threonate + NAD(+)


name: [protein]-D-aspartate + S-adenosyl-L-methionine <=> [protein]-D-aspartate methyl ester + S-adenosyl-L-homocysteine


name: H2O + L-alanine + O2 = H2O2 + NH4(+) + pyruvate


name: KAL1 binds FGFR1c (Caenorhabditis elegans)


name: CYP17A1 cleaves 17aHPREG to DHA (Mus musculus)


name: AH2 + demethylspheroidene => 1-hydroxy-all-trans-1,2-dihydro-neurosporene + A


name: 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O => ADP + H(+) + N-acetyl-D-muramate 6-phosphate


name: ACEIs translocate from ER lumen to extracellular region (Homo sapiens)


name: Formation of P-TEFb complex (Homo sapiens)


name: a lipid A disaccharide + H(+) + UDP => a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine


name: (2S,3S)-3-hydroxyasparagine + CO2 + succinate => 2-oxoglutarate + L-asparagine + O2


name: HDHD1:Mg2+ dephosphorylates PURIDP (Caenorhabditis elegans)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Caenorhabditis elegans)


name: QPRT transfers PRIB to QUIN to form NAMN (Dictyostelium discoideum)


name: O-acetyl-L-serine + pyrazole => 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)


name: PON1,3 hydrolyse ATVL to ATV (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + octadecanoate


name: (9Z)-hexadecenoyl-CoA + H2O => (9Z)-hexadecenoate + CoA + H(+)


name: acetyl-CoA + AH2 + 3 H(+) + 3 malonyl-CoA = A + 3 CO2 + 4 CoA + H2O + orsellinaldehyde


name: H(+)(out) + phosphate(out) => H(+)(in) + phosphate(in)


name: L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Autophosphorylation of insulin receptor (Rattus norvegicus)


name: an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O => a 2'-deoxyguanosine in DNA + H(+) + lactate


name: dihydrodigitoxin + 2 Fe(III)-[cytochrome c] => digitoxin + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)


name: (3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) => [(3R)-hydroxybutanoate](n+1) + CoA


name: PDSS1,2 ligates FPP to IPPP (Saccharomyces cerevisiae)


name: fumarate(out) + 2 H(+)(out) => fumarate(in) + 2 H(+)(in)


name: E2F6 binds the PRC1 complex (Bos taurus)


name: aldehydo-D-glucose 6-phosphate + L-lysyl-[protein] = H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein]


name: LYZ binds bacterial peptidoglycan (Mus musculus)


name: beta-D-galactosyl-(1<->1')-N-hexadecanoylsphinganine + H2O => beta-D-galactose + N-hexadecanoylsphinganine


name: melibiose(in) + Na(+)(in) <=> melibiose(out) + Na(+)(out)


name: Thr-180 of ULK1 is phosphorylated (Drosophila melanogaster)


name: CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + NADP(+)


name: H2O + N-acetyl-beta-alanine <=> acetate + beta-alanine


name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Sus scrofa)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Bos taurus)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Canis familiaris)


name: 1-(9Z-octadecenoyl)-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O = (9Z)-octadecenoate + 2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-1D-myo-inositol + H(+)


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + NADP(+) => 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + NADPH


name: ULK1 phosphorylates Beclin-1 (Mus musculus)


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Sus scrofa)


name: dopamine + formaldehyde <=> H2O + norsalsolinol


name: FPGS-2 transforms THF to THFPG (Saccharomyces cerevisiae)


name: acetyl-CoA + N-terminal L-methionyl-L-glutamyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein]


name: Agmatine + H2O <=> putrescine + urea (Homo sapiens)


name: (1S,4R)-isodihydrocarvone + H(+) + NADPH + O2 => (3S,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Mus musculus)


name: 2-(phosphinatomethylidene)butanedioate + H2O => phosphinomethylmalate


name: MAPK-dependent phosphorylation of KARS (Drosophila melanogaster)


name: DHFR2 reduces FOLA to DHF (Schizosaccharomyces pombe)


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Canis familiaris)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Mus musculus)


name: germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => (+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP (Danio rerio)


name: GGPS1 hexamer transfers IPPP to GPP (Dictyostelium discoideum)


name: N,N-dimethylglycine + S-adenosyl-L-methionine => glycine betaine + H(+) + S-adenosyl-L-homocysteine


name: (2S)-3-sulfopropanediol + NAD(+) => (2S)-3-sulfolactaldehyde + H(+) + NADH


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Plasmodium falciparum)


name: (-)-alpha-cuprenene + diphosphate => (2E,6E)-farnesyl diphosphate


name: PHLPP dephosphorylates S473 in AKT (Homo sapiens)


name: SEC4C,D bind GOSR2 and STX5 (Rattus norvegicus)


name: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate => beta-D-fructose 6-phosphate + D-erythrose 4-phosphate


name: ATP binding to HSP90 triggers conformation change (Sus scrofa)


name: H2O + L-glutamate + O2 => 2-oxoglutarate + H2O2 + NH4(+)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Sus scrofa)


name: 16-hydroxyhexadecanoyl-CoA + AMP + diphosphate => 16-hydroxyhexadecanoate + ATP + CoA


name: Na(+)(in) + O-butanoyl-(R)-carnitine(in) => Na(+)(out) + O-butanoyl-(R)-carnitine(out)


name: Gq activation by TP receptor (Gallus gallus)


name: GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate => GDP + H(+) + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: (2E,6E)-farnesyl diphosphate + H2O = (2Z,6E)-hedycaryol + diphosphate


name: (1S,2R,4R)-neoisodihydrocarveol + NAD(+) => (1S,4R)-isodihydrocarvone + H(+) + NADH


name: H(+) + L-methionine => 3-(methylsulfanyl)propanamine + CO2


name: an acyl-CoA + dihydroxyacetone phosphate => a 1-acylglycerone 3-phosphate + CoA


name: hexadecan-1-ol + NADP(+) => H(+) + hexadecanal + NADPH


name: interleukin-1 type I receptor antagonist activity


name: SPHK2 binds SPHK2 inhibitors (Bos taurus)


name: (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: diacylglycerol + H2O -> 2-acylglycerol + fatty acid (Homo sapiens)


name: Ubiquitinated Orc1 enters the cytosol (Caenorhabditis elegans)


name: Carbonic anhydrase hydrates carbon dioxide (cytosol) (Xenopus tropicalis)


name: D-threo-isocitrate + NADP(+) <=> (S)-oxalosuccinate + H(+) + NADPH


name: H2O + L-glutamate + O2 <=> 2-oxoglutarate + H2O2 + NH4(+)


name: SCARB1 (SR-BI, CLA-1) binds ligands (Bos taurus)


name: calycosin + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + pseudobaptigenin


name: I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol (Mus musculus)


name: HEXB cleaves the terminal GalNAc from small HA fragments (Drosophila melanogaster)


name: (S)-reticuline + S-adenosyl-L-methionine = (S)-codamine + H(+) + S-adenosyl-L-homocysteine


name: PIAS4 SUMOylates PARP1 with SUMO1 (Xenopus tropicalis)


name: NADP(+) + tetradecasphinganine <=> 3-oxotetradecasphinganine + H(+) + NADPH


name: alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose => alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: NPAS4 binds ARNTL (BMAL1) (Rattus norvegicus)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 5-oxopentanoate + H(+)


name: alcohol dehydrogenase (NAD+) activity, iron-dependent


name: H2O + O2 + tyramine = (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)


name: androst-4-ene-3,17-dione + H(+) + NADH + O2 <=> 9alpha-hydroxy-androst-4-ene-3,17-dione + H2O + NAD(+)


name: (3R)-3-[(carboxylmethyl)amino]decanoate + H(+) + holo-[ACP] => (2E)-decenoyl-[ACP] + glycine + H2O


name: (E)-cinnamate + H(+) + NADH + O2 => (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+)


name: ADA deamidates RBV (Caenorhabditis elegans)


name: orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate (Gallus gallus)


name: 20-oxo-5-O-beta-D-mycaminosyltylonolide + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-O-beta-D-mycaminosyltylonolide + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Drosophila melanogaster)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Mus musculus)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(5,6-epoxy-8Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Canis familiaris)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Gallus gallus)


name: acetate + L-cysteine => H2O + N-acetyl-L-cysteine


name: Recruitment of CstF to the CPSF Bound Pre-mRNA (Bos taurus)


name: MMP14:TIMP2 binds proMMP2 (Homo sapiens)


name: De novo formation of eIF2:GTP (Rattus norvegicus)


name: Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE (Homo sapiens)


name: p115-RhoGEF activation of RHOA (Sus scrofa)


name: 1''-O-acetyl-ADP-alpha-D-ribose + H2O <=> acetate + ADP-D-ribose + H(+)


name: (9Z)-tetradecenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(11Z)-hexadecenoyl-CoA + CO2 + CoA


name: Latent TGF-beta-3 binds integrins (Canis familiaris)


name: H(+)(in) + spermidine(out) = H(+)(out) + spermidine(in)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + octadecanoyl-CoA = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: D-maltoheptaono-1,5-lactone + H2O => D-maltoheptaonate + H(+)


name: acetate + spermine => H2O + N(1)-acetylspermine


name: H(+) + NADPH + zymosterone = NADP(+) + zymosterol


name: GNLY binds the bacterial cell surface (Gallus gallus)


name: Exocytosis of ficolin-rich granule lumen proteins (Plasmodium falciparum)


name: (2E,6E)-farnesyl diphosphate = (-)-beta-barbatene + diphosphate


name: H(+) + o-quinone methide + penilactone D => penilactone B


name: [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine => [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate


name: an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + S-adenosyl-L-methionine => an N-methylornithine lipid + H(+) + S-adenosyl-L-homocysteine


name: CYP2C19 5-hydroxylates omeprazole (Homo sapiens)


name: 2xTNFR2 binds TNFA trimer:TNFR2 (Mus musculus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Schizosaccharomyces pombe)


name: ING2-bound EP300 acetylates TP53 (Homo sapiens)


name: FKBP1A binds tacrolimus (Schizosaccharomyces pombe)


name: 2-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + testosterone


name: abscisate(in) + ATP + H2O = abscisate(out) + ADP + H(+) + phosphate


name: L-phenylalanine(out) + L-serine(in) => L-phenylalanine(in) + L-serine(out)


name: 7-chloro-L-tryptophan + O2 = 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2


name: (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + NADP(+)


name: L-glutamate(in) + orotate(out) = L-glutamate(out) + orotate(in)


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Xenopus tropicalis)


name: a dicarboxylate(in) + estrone 3-sulfate(out) <=> a dicarboxylate(out) + estrone 3-sulfate(in)


name: 2 H2O + julichrome Q6-6 + 2 oxidized [2Fe-2S]-[ferredoxin] => H(+) + 2 julichrome Q6 + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)


name: 16 ATP + 16 H2O + N2 + 4 reduced [flavodoxin] => 16 ADP + 18 H(+) + H2 + 2 NH4(+) + 4 oxidized [flavodoxin] + 16 phosphate


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate + 6-hydroxymellein = diphosphate + verruculide C


name: Activated FGFR2 phosphorylates SHC1 (Bos taurus)


name: Defective SI does not hydrolyze Mal (Homo sapiens)


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Caenorhabditis elegans)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => (R)-nephthenol + diphosphate


name: FADH2-C4alpha-hydroperoxide + NADH + rifampicin <=> FADH2 + H(+) + H2O + NAD(+) + rifampicin hemiaminal


name: cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase] => apo-[corrinoid adenosyltransferase] + cob(II)yrinate a,c diamide


name: p-Y693-STAT4 dissociates after IL12:IL12R interaction (Mus musculus)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Drosophila melanogaster)


name: dihydro-ML-236C carboxylate + O2 + reduced [NADPH--hemoprotein reductase] => 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: methyl transfer-driven active transmembrane transporter activity


name: SUMOylation of TOP1 with SUMO1 (Dictyostelium discoideum)


name: H(+) + N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine + nicotinamide => 2'-deoxyguanosine + NAD(+)


name: (1S)-3-methyl-cyclohexylamine + H2O + NAD(+) => 3-methylcyclohexanone + H(+) + NADH + NH4(+)


name: PTK2beta binds alphaVbeta3 (Gallus gallus)


name: RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA (Rattus norvegicus)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: ATP + L-serine + tRNA(Sec) <=> AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)


name: AGT(34-41) binds to AGTR2 (Drosophila melanogaster)


name: Abortive Initiation After Second Transition (Dictyostelium discoideum)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Homo sapiens)


name: cortisone + H(+) + NADPH => cortisol + NADP(+)


name: cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25S)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: MTMR14, MTMR3 dephosphorylate PI3P (Sus scrofa)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Caenorhabditis elegans)


name: O2 + reduced [NADPH--hemoprotein reductase] + teasterone <=> 7-oxateasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HPN heterodimer cleaves pro-HGF to form HGF dimer (Xenopus tropicalis)


name: eicosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-eicosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: H2O + ochratoxin A = L-phenylalanine + ochratoxin alpha


name: (9Z,12Z)-octadecadienoate + H2O = (10S)-hydroxy-(12Z)-octadecenoate


name: 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H2O <=> 6-deoxy-6-sulfo-D-gluconate + H(+)


name: Activation of Ca-permeable Kainate receptors (Canis familiaris)


name: RAC2 GAPs stimulate RAC2 GTPase activity (Xenopus tropicalis)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: bromochloromethane + H2O => bromide + chloride + formaldehyde + 2 H(+)


name: 6-diazo-5-oxo-L-norleucine + acetyl-CoA <=> CoA + H(+) + N(alpha)-acetyl-6-diazo-5-oxo-L-norleucine


name: HDAC1:2-containing complex deacetylate histones (Sus scrofa)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Drosophila melanogaster)


name: RAB33B:GTP binds RIC1:RGP1 (Mus musculus)


name: EP300 acetylates histone H2A, H2B, H3, H4 (Bos taurus)


name: A + Fe(II)-heme i + H2O = AH2 + Fe(II)-hydroxyheme i


name: 2 a quinone + H(+) + NADH <=> 2 a 1,4-benzosemiquinone + NAD(+)


name: FUNDC1 is phosphorylated by CK2 (Caenorhabditis elegans)


name: Dephosphorylation of PAG by SHP2 (Xenopus tropicalis)


name: decanoyl-[ACP] + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = dec-9-ynoyl-[ACP] + 4 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Canis familiaris)


name: 3,4-dihydroxybenzoate + H(+) <=> catechol + CO2


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Homo sapiens)


name: glutamate uptake by astrocytes (Rattus norvegicus)


name: (2E)-butenoyl-[ACP] + H(+) + NADH = butanoyl-[ACP] + NAD(+)


name: phycoerythrobilin-L-cysteinyl(84)-[C-phycoerythrin beta-subunit] => (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[C-phycoerythrin beta-subunit]


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Rattus norvegicus)


name: 2 (2R)-3-phosphoglycerate + 2 H(+) = CO2 + D-ribulose 1,5-bisphosphate + H2O


name: p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP (Danio rerio)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 16,17-epoxy-(7Z,10Z,13Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity


name: acetoacetyl-CoA + L-glutamate => (3S)-3-aminobutanoyl-CoA + 2-oxoglutarate


name: sphing-4-enine 1-phosphate(out) => sphing-4-enine 1-phosphate(in)


name: PIAS2-2 SUMOylates SUZ12 with SUMO1 (Mus musculus)


name: lipoxin A4 + NAD(+) => 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H(+) + NADH


name: CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Drosophila melanogaster)


name: PDE4A binds PDE4A inhibitors (Sus scrofa)


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Mus musculus)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Bos taurus)


name: TTYH1 transports cytosolic Cl- to extracellular region (Dictyostelium discoideum)


name: (R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: Phosphorylation of STAT1 by JAK kinases (Mus musculus)


name: 7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine <=> adenine + epoxyqueuosine(34) in tRNA + 2 H(+) + L-methionine


name: SYK activation by SRC (Rattus norvegicus)


name: VAV2 is a GEF for Rho/Rac family kinases (Gallus gallus)


name: 26S proteasome degrades HIFalpha (Sus scrofa)


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Homo sapiens)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+) => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O


name: alpha-D-glucose 6-phosphate + O-phospho-L-seryl-[protein] => alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]


name: PKA phosphorylates PDE4B (Gallus gallus)


name: SHC1-2 bound to MET recruits GRB2:SOS1 (Bos taurus)


name: (2R)-3-phosphoglycerate + GTP + H(+) => 3-[(R)-glyceryl]-diphospho-5'-guanosine + diphosphate


name: USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Gallus gallus)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Homo sapiens)


name: acetyl-CoA + 6 H(+) + holo-[ACP] + 6 malonyl-CoA => 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] + 6 CO2 + 7 CoA


name: mismatch base pair DNA N-glycosylase activity


name: glycolaldehyde + H2O + NAD(+) = glycolate + 2 H(+) + NADH


name: 3,4-dichlorocatechol + O2 = (2Z,4Z)-2,3-dichloromuconate + 2 H(+)


name: 5-methyl-3-oxohexanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxy-5-methylhexanoyl-[ACP] + NADP(+)


name: RAC1 and CDC42 activate PAK3 (Rattus norvegicus)


name: H(+) + o-quinone methide + peniphenone D <=> penilactone A


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: 13-cis-retinol + NAD(+) <=> 13-cis-retinal + H(+) + NADH


name: HSP70 binds to HSP40:nascent protein (Xenopus tropicalis)


name: Factor H displaces Bb (Xenopus tropicalis)


name: Formation of active mTORC1 complex (Drosophila melanogaster)


name: TFIIF-class transcription factor complex binding


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O


name: Type B histone acetlytransferase complex acetylates histone H4 (Saccharomyces cerevisiae)


name: MRN complex bound to DNA ends recruits ATM (Drosophila melanogaster)


name: 2-O-caffeoylglucarate + L-quinate => chlorogenate + D-glucarate


name: IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Bos taurus)


name: AH2 + serpentine => A + dihydroserpentine


name: H(+) + NADPH + O2 + protodeoxyviolaceinate = deoxyviolaceinate + H2O + NADP(+)


name: glycyl-L-glutamate + H2O = glycine + L-glutamate


name: RAC2 binds effectors at the mitochondrial outer membrane (Bos taurus)


name: androsta-1,4-diene-3,17-dione + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a 2-acyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycerol 3-phosphate + choline + H(+)


name: D-xylonate <=> 2-dehydro-3-deoxy-D-arabinonate + H2O


name: H2O + octanedioyl-CoA = CoA + H(+) + octanedioate


name: RFK:Mg2+ phosphorylates RIB (Schizosaccharomyces pombe)


name: Clathrin internalises EPH:EFN complexes (Gallus gallus)


name: H2O + N(8)-acetylspermidine => acetate + spermidine


name: a fatty acylamide + H2O <=> a fatty acid + NH4(+)


name: 5alpha-androstan-3,17-dione + A => AH2 + androst-4-ene-3,17-dione


name: MscR reduces nitrosomycothiol to ammonia (Homo sapiens)


name: atRAL is reduced to atROL (Homo sapiens)


name: TNF-alpha inhibitors bind to soluble TNF trimer (Mus musculus)


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Homo sapiens)


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Homo sapiens)


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Rattus norvegicus)


name: HNF1A-dependent synthesis of FOXA3 (Homo sapiens)


name: L-glutamine(in) + L-serine(out) + Na(+)(out) => L-glutamine(out) + L-serine(in) + Na(+)(in)


name: ATP + di-trans,octa-cis-undecaprenol => ADP + di-trans,octa-cis-undecaprenyl phosphate + H(+)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Saccharomyces cerevisiae)


name: ergosteryl 3-beta-D-glucoside + H2O <=> D-glucose + ergosterol


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Rattus norvegicus)


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Danio rerio)


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Schizosaccharomyces pombe)


name: D-fucose(in) + H(+)(in) = D-fucose(out) + H(+)(out)


name: The UDP/CysLT (P2Y17) receptor can bind UTP (Canis familiaris)


name: N-WASP binds ARP2/3 and G-actin (Gallus gallus)


name: 1D-myo-inositol 1,2,3,6-tetrakisphosphate + H2O <=> 1D-myo-inositol 1,2,3-trisphosphate + phosphate


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Homo sapiens)


name: TFAP2C homodimer binds MYC and KDM5B (Homo sapiens)


name: Beta-tubulin:GTP: Cofactor A+ Cofactor D ->  Beta-tubulin:GTP:Cofactor D + Cofactor A (Homo sapiens)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Homo sapiens)


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Canis familiaris)


name: Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)


name: MECP2 mutants R106W, D121G, R133H, S134F, T158M and T158A do not bind to 5mC-DNA (Homo sapiens)


name: Orexin 2 receptor can bind orexin-B neuropeptide (Bos taurus)


name: (3S)-hydroxyoctanedioyl-CoA + NAD(+) => 3-oxooctanedioyl-CoA + H(+) + NADH


name: dimethylallyl diphosphate + H2O + yaequinolone E <=> [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate


name: ARL2:GTP bind PDE6D on KRAS4B (Caenorhabditis elegans)


name: glutamate-cysteine ligase catalytic subunit binding


name: (9Z,12Z)-octadecadienoate + O2 = 13-hydroperoxy-(9Z,11E)-octadecadienoate


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)


name: 3-oxoeicosanoyl-CoA + H(+) + NADPH <=> (3R)-hydroxyeicosanoyl-CoA + NADP(+)


name: calcium-activated potassium channel activity


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Sus scrofa)


name: Importin-8 binds AGO2:miRNA (Homo sapiens)


name: FGFR2c mutants bind an expanded range of ligands (Homo sapiens)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Mus musculus)


name: Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Mus musculus)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Xenopus tropicalis)


name: PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Bos taurus)


name: Assembly of telomerase RNP (Gallus gallus)


name: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine => H(+) + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Drosophila melanogaster)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Saccharomyces cerevisiae)


name: 4-hydroxy-L-lysyl-[protein] + CO2 + succinate => 2-oxoglutarate + L-lysyl-[protein] + O2


name: AH2 + cob(III)alamin <=> A + cob(I)alamin + 2 H(+)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Homo sapiens)


name: HSP90 dissociates from LAMP2a (Homo sapiens)


name: 2-hydroxyhexadecanoyl-CoA + sphinganine = CoA + H(+) + N-(2-hydroxyhexadecanoyl)-sphinganine


name: Formation of lysyl-pyridinoline cross-links (Homo sapiens)


name: demethylluteothin + S-adenosyl-L-methionine <=> luteothin + S-adenosyl-L-homocysteine


name: TRIP11:IFT20 dissociates (Gallus gallus)


name: Phosphorylation of YAP by LATS2 (Homo sapiens)


name: Formation of the CE:GMP intermediate complex (Homo sapiens)


name: 8-oxo-dAMP + H(+) + phosphate => 8-oxo-dADP + H2O


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H(+) + phosphocholine => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O


name: Translocation of Ezrin to plasma membrane (Drosophila melanogaster)


name: Transhomodimerization of Nectin-like (Necl) proteins (Gallus gallus)


name: PLG(20-810) binds aprotinin (Gallus gallus)


name: (4R)-hydroxysphinganine + hexacosanoyl-CoA => CoA + H(+) + N-hexacosanoyl-(4R)-hydroxysphinganine


name: Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Canis familiaris)


name: RPS6KA1-dependent phosphorylation of MITF-M (Mus musculus)


name: (R)-S-adenosyl-L-methionine + H2O = adenosine + H(+) + L-methionine


name: SNAI1 binds the CLDN7 gene (Homo sapiens)


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Pol II elongation complex moves on the template as transcript elongates (Canis familiaris)


name: 4-methylsulfanyl-2-oxobutanoate + L-glutamine => 2-oxoglutaramate + L-methionine


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Dictyostelium discoideum)


name: DVL2 is phosphorylated by PKC (Caenorhabditis elegans)


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose = alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base = a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-4R-hydroxysphingoid base


name: Change of PKC theta conformation (Homo sapiens)


name: nicotinate(in) + orotate(out) => nicotinate(out) + orotate(in)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Homo sapiens)


name: phosphate + pyridoxamine => H2O + pyridoxamine 5'-phosphate


name: Binding of TFIIE to the growing preinitiation complex (Drosophila melanogaster)


name: 3,4,5-trihydroxybenzoate + UDP-alpha-D-glucose <=> 1-O-galloyl-beta-D-glucose + UDP


name: fibroblast growth factor receptor activity


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)


name: O2 + reduced [NADPH--hemoprotein reductase] + taurochenodeoxycholate = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + taurohyocholate


name: H2O + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose => UDP-N-acetyl-alpha-D-glucosamine


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Dictyostelium discoideum)


name: 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + NADP(+) => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADPH


name: MITF-M dimer binds the CCND1 gene (Homo sapiens)


name: MDM2 translocates to the cytosol (Mus musculus)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Bos taurus)


name: 2-acyl LPI is acylated to PI by MBOAT7 (Dictyostelium discoideum)


name: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Sus scrofa)


name: IL12A:IL12B translocates from late endosome lumen to extracellular region (Homo sapiens)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NH4(+) => (6S)-5,6,7,8-tetrahydrofolate + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein]


name: Oligomerization of Bcl10 (Canis familiaris)


name: SLC51A:SLC51B transports bile salts from cytosol to extracellular region (Rattus norvegicus)


name: FMO1:FAD N-oxidises TAM (Caenorhabditis elegans)


name: RAC3 binds effectors at the plasma membrane (Dictyostelium discoideum)


name: Translocation of Cdc25 to the nucleus (Gallus gallus)


name: Activation of GT (Saccharomyces cerevisiae)


name: (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA + H(+) + NADPH <=> (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Homo sapiens)


name: Conversion of glyoxylate to oxalate (Danio rerio)


name: SUMOylation of RAD52 with SUMO1 (Rattus norvegicus)


name: PLC gamma 2-mediated PIP2 hydrolysis (Dictyostelium discoideum)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Homo sapiens)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Sus scrofa)


name: 25-hydroxy 3-oxocholestane + AH2 => 3-oxocholestane + A + H2O


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Saccharomyces cerevisiae)


name: Binding of A1CF to stem-looped RNA (Homo sapiens)


name: SRC-1 phosphorylates SHB (Gallus gallus)


name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Schizosaccharomyces pombe)


name: NADP(+) + octan-1-ol => H(+) + NADPH + octanal


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + H2O = 1D-myo-inositol 2,3,4,5-tetrakisphosphate + phosphate


name: ABC-type peptide antigen transporter activity


name: N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Rattus norvegicus)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Canis familiaris)


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Bos taurus)


name: Defective ALG11 does not transfer Man to the N-glycan precursor (Homo sapiens)


name: (2E,11Z,14Z)-eicosatrienoyl-CoA + H2O => (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA


name: GST trimers transfer GS from GSH to luminal substrates (Sus scrofa)


name: N-acetyl-L-aspartate(in) + 3 Na(+)(in) => N-acetyl-L-aspartate(out) + 3 Na(+)(out)


name: 2-oxoglutarate + O2 + penicillin N <=> CO2 + deacetoxycephalosporin C + H2O + succinate


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Bos taurus)


name: a dicarboxylate(in) + L-sepiapterin(out) => a dicarboxylate(out) + L-sepiapterin(in)


name: Formation of the RBBP5:ASH2L heterodimer (Schizosaccharomyces pombe)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate => 1D-myo-inositol 1,3,4,6-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate


name: Elongation by POLH (Caenorhabditis elegans)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Schizosaccharomyces pombe)


name: H2O + N-ethylglycine + O2 = ethylamine + glyoxylate + H2O2


name: prosolanapyrone III => (-)-solanapyrone A


name: Recruitment of POLB to the AP site (Mus musculus)


name: H2O + lactose 6-phosphate = beta-D-glucose + D-galactose 6-phosphate


name: (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Sus scrofa)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Drosophila melanogaster)


name: Phenol can form a sulfate conjugate (Homo sapiens)


name: 1-phospho-alpha-D-glucuronate + H(+) + UTP => diphosphate + UDP-alpha-D-glucuronate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + FAD + H(+) <=> (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + FADH2


name: di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: a 2'-deoxyribonucleoside 5'-phosphate + H2O => a 2'-deoxyribonucleoside + phosphate


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 15,20-dihydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Sus scrofa)


name: CRLF1:CLCF1 binds CNTRF (Rattus norvegicus)


name: ADP + H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(out) + phosphate => ATP + H2O + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(in)


name: a 1,2-diacylglycerol + H2O => a 2-acylglycerol + a carboxylate + H(+)


name: USP9X (FAM) binds to ubiquitinated SMAD4 (Bos taurus)


name: H(+) + keto-D-tagaturonate + NADH => D-altronate + NAD(+)


name: 4-aminobenzoate + 2 H(+) + NADPH + O2 => 4-aminophenol + CO2 + H2O + NADP(+)


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + N-(2,3-dihydroxybenzoyl)-L-serine => Fe(III)-{di[N-(2,3-dihydroxybenzoyl)-L-seryl]-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + H(+) + H2O


name: PI3-kinase binds to the active receptor (Drosophila melanogaster)


name: SPN27A binds to and inhibits EA protease activity (Drosophila melanogaster)


name: [DsrC protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide => [DsrC protein]-dithiol + 2 AH2 + H(+) + sulfite


name: inorganic molecular entity transmembrane transporter activity


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Xenopus tropicalis)


name: FLT3LG dimer binds FLT3 (Canis familiaris)


name: L-selenocysteine + S-methyl-L-methionine => H(+) + L-methionine + Se-methyl-L-selenocysteine


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Caenorhabditis elegans)


name: RNF152 polyubiquitinates RRAGA (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: H(+) + hispidin + NADPH + O2 <=> 3-hydroxyhispidin + H2O + NADP(+)


name: H2O + L-seryl-tRNA(Lys) = L-serine + tRNA(Lys)


name: 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+) => 2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate


name: a ubiquinol + acetaldehyde => a ubiquinone + ethanol


name: HCO3- transport through ion channel (Canis familiaris)


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Plasmodium falciparum)


name: pyridoxine transmembrane transporter activity


name: D-mannitol 1-phosphate + H2O <=> D-mannitol + phosphate


name: CDP(out) + UTP(in) <=> CDP(in) + UTP(out)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Plasmodium falciparum)


name: ADP(out) + AMP(in) => ADP(in) + AMP(out)


name: (2R,3R)-dihydroquercetin + 2-oxoglutarate + O2 <=> CO2 + H(+) + H2O + quercetin + succinate


name: [protein]-disulfide + H2O + phylloquinone => 2,3-epoxyphylloquinone + [protein]-dithiol


name: dehydroepiandrosterone 3-sulfate + H2O <=> 3beta-hydroxyandrost-5-en-17-one + H(+) + sulfate


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Bos taurus)


name: Interaction of Tie2 and Dok-2 (Rattus norvegicus)


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Mus musculus)


name: NLK mRNA translation controlled by miR-92b (Homo sapiens)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Sus scrofa)


name: ATP + glutathione + glutathionylspermidine = ADP + H(+) + phosphate + trypanothione


name: H2O + monomethyl sulfate => H(+) + methanol + sulfate


name: (Z)-non-6-en-1-ol + NADP(+) = (Z)-non-6-enal + H(+) + NADPH


name: dihydroserpentine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => ajmalicine + O2 + reduced [NADPH--hemoprotein reductase]


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Canis familiaris)


name: Phosphorylation of STAT2 (Xenopus tropicalis)


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Xenopus tropicalis)


name: SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ (Dictyostelium discoideum)


name: glycero-2-phosphocholine + H2O => glycerol + H(+) + phosphocholine


name: Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Drosophila melanogaster)


name: dehydroabietadienol + H(+) + NADPH + O2 = dehydroabietadienal + 2 H2O + NADP(+)


name: 3,4-dihydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 <=> 3,5-dibromobenzene-1,2-diol + CO2 + 4 H2O + 2 NADP(+)


name: Interaction of beta-2-microglobulin (B2M) chain with  class I HC (Gallus gallus)


name: PRLR is phosphorylated at Ser-349 (Xenopus tropicalis)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Drosophila melanogaster)


name: CHGA-derived peptide binds the bacterial cell surface (Xenopus tropicalis)


name: 3''-deamino-3''-oxonicotianamine + L-glutamate => 2-oxoglutarate + nicotianamine


name: PXLP-K333-GADL1 decarboxylates acidic AAs (Homo sapiens)


name: PTHP is reduced to BH4 by sepiapterin reductase (SPR) (Rattus norvegicus)


name: (E)-caffeoyl-CoA + quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside <=> CoA + H(+) + quercetin 3-O-[(6-O-[(E)-caffeoyl]-beta-D-glucosyl)-(1->2)-beta-D-glucoside]


name: NAD-dependent histone H3K9 deacetylase activity


name: SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters (Homo sapiens)


name: Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Rattus norvegicus)


name: (5S)-hydroperoxy-(6E,8Z)-octadecadienoate + 2 glutathione = (5S)-hydroxy-(6E,8Z)-octadecadienoate + glutathione disulfide + H2O


name: P4HB:4-Hyp collagen propeptides dissociates (Mus musculus)


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Homo sapiens)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Sus scrofa)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O => an N-acylsphing-4-enine + D-glucose


name: a 5'-end 5'-phospho-ribonucleoside-RNA + H2O => a 5'-end dephospho-ribonucleoside-RNA + phosphate


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Mus musculus)


name: Association of DFF40 with chromatin (Mus musculus)


name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Rattus norvegicus)


name: NTPDase8 hydrolyzes nucleoside triphosphates (Rattus norvegicus)


name: SUMOylation of TOP2B with SUMO1 (Gallus gallus)


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Homo sapiens)


name: [(1->6)-alpha-D-glucosyl](n) + sucrose = (1->3)-alpha-D-glucosyl-[(1->6)-alpha-D-glucosyl](n) + D-fructose


name: MMAB adenosylates cob(I)alamin (Bos taurus)


name: SRC-1 phosphorylates p-Y397-PTK2 (Mus musculus)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Schizosaccharomyces pombe)


name: Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene (Homo sapiens)


name: (R)-4-dehydropantoate + H2O + NAD(+) => (R)-3,3-dimethylmalate + 2 H(+) + NADH


name: p-4Y-SIRPA:CD47 binds GRB2-1 (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + cholesterol <=> a 1-acyl-sn-glycero-3-phosphocholine + a cholesterol ester


name: PP2A dephosphorylates inactive RAFs (Rattus norvegicus)


name: (E)-feruloyl-CoA + H(+) + malonyl-CoA = (E)-feruloylacetyl-CoA + CO2 + CoA


name: Interaction of other tyrosine kinases with p-KIT (Xenopus tropicalis)


name: Interleukin-27 translocates from the ER lumen to the extracellular region (Homo sapiens)


name: Phosphorylation of IRS (Rattus norvegicus)


name: 2'-deoxyadenosine + H(+) + triphosphate => dATP + H2O


name: decanoyl-[ACP] + H2O <=> decanoate + H(+) + holo-[ACP]


name: p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Rattus norvegicus)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: (S)-reticuline + 2-oxoglutarate + O2 = (S)-6-O-demethylreticuline + CO2 + formaldehyde + succinate


name: ATP + CoA + pseudomonate C => AMP + diphosphate + pseudomonoyl-CoA C


name: hexadecanoyl-CoA + sphinga-(4E,8Z)-dienine <=> CoA + H(+) + N-hexadecanoylsphinga-(4E,8Z)-dienine


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Gallus gallus)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Mus musculus)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Bos taurus)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Mus musculus)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + ATP


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + H(+) + hexadecanoate


name: p-S318,221-HuR binds mRNA (Homo sapiens)


name: CPTP transports C1P from plasma membrane to Golgi membrane (Homo sapiens)


name: 5,6,7,8-tetrahydromethanopterin + H(+) + N-formylmethanofuran => methanofuran + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Sus scrofa)


name: formyl-CoA + succinate => formate + succinyl-CoA


name: eicosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 2-hydroxyeicosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: L-methionine(in) + Na(+)(in) => L-methionine(out) + Na(+)(out)


name: Translocation of PLC-gamma1 to PIP2 (Plasmodium falciparum)


name: ETA is phosphorylated to PETA by CHK/ETNK (Danio rerio)


name: 6-oxohexanoate + H2O + NADP(+) <=> 2 H(+) + hexanedioate + NADPH


name: ATP + H2O + L-methionine(out) => ADP + H(+) + L-methionine(in) + phosphate


name: 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O => 2-glutaroyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity


name: The SMAD2/3:SMAD4 complex transfers to the nucleus (Rattus norvegicus)


name: (2E)-hexenoyl-CoA + H(+) + NADPH => hexanoyl-CoA + NADP(+)


name: (E)-sinapate + UDP-alpha-D-glucose => 4-O-(beta-D-glucosyl)-trans-sinapate + H(+) + UDP


name: a rhodoquinone + succinate = a rhodoquinol + fumarate


name: 1-phospho-alpha-D-glucuronate + H(+) + UTP = diphosphate + UDP-alpha-D-glucuronate


name: "diadenosine hexaphosphate hydrolase (ATP-forming)"


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Xenopus tropicalis)


name: FOXG1 binds FOXO:SMAD complexes (Danio rerio)


name: Cleavage of Procaspase-7 by the apoptosome (Rattus norvegicus)


name: dodecanoyl-CoA + H2O => CoA + dodecanoate + H(+)


name: anthraniloyl-CoA + methanol => CoA + O-methyl anthranilate


name: penilactone A => H(+) + o-quinone methide + peniphenone D


name: Phosphorylated MAPKs translocate into the nucleus (Caenorhabditis elegans)


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Sus scrofa)


name: (11R)-dihydroartemisinic aldehyde + NADP(+) <=> (+)-artemisinic aldehyde + H(+) + NADPH


name: (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH <=> (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + NADP(+)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + an acyl-CoA => a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + CoA


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Dictyostelium discoideum)


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Mus musculus)


name: acetate + N'-monoacetylchitobiose-6'-phosphate => diacetylchitobiose-6'-phosphate + H2O


name: CBL autoubiquitinates (Plasmodium falciparum)


name: UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out) <=> UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in)


name: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate


name: aurachin C epoxide => 2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one


name: an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] <=> a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: holo-[ACP] + octanoyl-AMP <=> AMP + H(+) + octanoyl-[ACP]


name: aculene D + L-prolyl-[peptidyl-carrier protein] <=> aculene B + holo-[peptidyl-carrier protein]


name: Activated FGFR1:p-FRS bind to PPTN11 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate => diphosphate + germacrene C


name: a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1balpha + CMP + H(+)


name: GLB1 hydrolyses a glycosaminoglycan (Rattus norvegicus)


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Mus musculus)


name: 4beta-hydroxymethyl-4alpha-methylzymosterol + H(+) + NADH + O2 <=> 4beta-formylmethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H2O + NAD(+)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Saccharomyces cerevisiae)


name: AMP + fumarate => N(6)-(1,2-dicarboxyethyl)-AMP


name: HSD17B3-like proteins reducde ANDST to TEST (Drosophila melanogaster)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-6-aminohexanoate + O2 <=> (1-deoxy-D-fructos-1-yl)amine + 6-oxohexanoate + H2O2


name: OSCAR binds collagen and SP-D (Bos taurus)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Rattus norvegicus)


name: 6-O-acetyl-beta-D-glucose + CoA => acetyl-CoA + beta-D-glucose


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Sus scrofa)


name: SFTPAs translocate from ER membrane to extracellular region (Homo sapiens)


name: (S)-malyl alpha-D-glucosaminide + L-cysteine = bacillithiol + H2O


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Danio rerio)


name: 3alpha(S)-strictosidine + H2O = secologanin + tryptamine


name: H(+) + H2O + N-isopropylammelide = cyanurate + isopropylamine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecylglycerol = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol


name: MAPKAPK2 phosphorylates HSF1 (Caenorhabditis elegans)


name: Full-length EA is cleaved by SNK serine protease (Drosophila melanogaster)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)


name: a fatty acyl-CoA + sphinga-4E,14Z-dienine => an N-acyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Sus scrofa)


name: 26S proteosome degrades ODC holoenzyme complex (Drosophila melanogaster)


name: Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (Mus musculus)


name: 2-oxindole-3-acetate + succinyl-CoA => (2-oxoindol-3-yl)acetyl-CoA + succinate


name: MRN complex binds shortened telomeres (Drosophila melanogaster)


name: Ubiquitinated Orc1 enters the cytosol (Plasmodium falciparum)


name: epsilon-(gamma-L-glutamyl)-L-lysine = 5-oxo-L-proline + L-lysine


name: SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Sus scrofa)


name: Caspase-mediated cleavage of MST3 (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + H2O = diphosphate + presilphiperfolan-8beta-ol


name: Slo3 Potassium Transport (Rattus norvegicus)


name: (2R,3S,4S)-leucocyanidin + 2-oxoglutarate + O2 <=> (4S)-2,3-dehydroleucocyanidin + CO2 + H(+) + H2O + succinate


name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate <=> 3-dehydroquinate + phosphate


name: Extracellular processing of novel PDGFs (Caenorhabditis elegans)


name: ING2 recruits EP300 to TP53 (Sus scrofa)


name: PLEKHA3,8 bind PI4P, ARF1 (Xenopus tropicalis)


name: Beclin-1 complex translocates to the ER (Saccharomyces cerevisiae)


name: diphosphate + H2O + Na(+)(in) = H(+) + Na(+)(out) + 2 phosphate


name: 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Rattus norvegicus)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Drosophila melanogaster)


name: L-isoleucine(in) + L-phenylalanine(out) = L-isoleucine(out) + L-phenylalanine(in)


name: (+)-valencene + diphosphate => (2E,6E)-farnesyl diphosphate


name: GAP binds to PDGF-beta receptors only (Bos taurus)


name: (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NAD(+) <=> 4-methylsulfanyl-2-oxobutanoate + H(+) + NADH


name: CARMA1 recruits MALT1 and BCL10 forming CBM Complex (Homo sapiens)


name: hydrogen sulfide + NAD(+) => NADH + sulfur


name: 3 Fe(III)-[cytochrome c] + hydroxylamine = 3 Fe(II)-[cytochrome c] + 3 H(+) + nitric oxide


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Xenopus tropicalis)


name: Translation of DNMT1 mRNA is repressed by miR-21 (Homo sapiens)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Saccharomyces cerevisiae)


name: octadecanoyl-CoA + sn-glycerol 3-phosphate <=> 1-octadecanoyl-sn-glycero-3-phosphate + CoA


name: 2-MAG is transacylated to DAG by PNPLA2/3 (Xenopus tropicalis)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Saccharomyces cerevisiae)


name: a 3beta-hydroxy-Delta(5)-steroid + NAD(+) => a 3-oxo-Delta(5)-steroid + H(+) + NADH


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Caenorhabditis elegans)


name: chlordecone alcohol + NADP(+) <=> chlordecone + H(+) + NADPH


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Mus musculus)


name: N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine


name: structural constituent of synapse-associated extracellular matrix


name: a 3-oxoacyl-CoA + H(+) + NADH => a (3R)-3-hydroxyacyl-CoA + NAD(+)


name: 4-hydroxy-3-methoxy-benzenemethanol + O2 => H2O2 + vanillin


name: cyclohexa-1,5-diene-1-carbonyl-CoA + H2O = 6-hydroxycyclohex-1-ene-1-carbonyl-CoA


name: (3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol + NADP(+) = (3R)-vestitone + H(+) + NADPH


name: (S)-sec-butylamine + H2O + NAD(+) <=> butan-2-one + H(+) + NADH + NH4(+)


name: (R)-metanephrine + H(+) + S-adenosyl-L-homocysteine => (R)-normetanephrine + S-adenosyl-L-methionine


name: a 1-acylglycerol + hexadecanoyl-CoA = an hexadecanoyl-acylglycerol + CoA


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Canis familiaris)


name: ABCE1 binds RNASEL, inhibiting it (Bos taurus)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Caenorhabditis elegans)


name: (2S,4R)-bornyl diphosphate => (2E)-geranyl diphosphate


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Sus scrofa)


name: O2 + tetradecanoate = (2R)-2-hydroperoxytetradecanoate


name: D-galactonate <=> 2-dehydro-3-deoxy-D-galactonate + H2O


name: Active LTK recruits GRB2:SOS1 (Homo sapiens)


name: Sema3A binds Nrp-1 bound to PlexinA (Gallus gallus)


name: CoA + H(+) + N-acetyl-D-glucosamine => acetyl-CoA + D-glucosamine


name: chloride(out) + Na(+)(out) + serotonin(out) = chloride(in) + Na(+)(in) + serotonin(in)


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Homo sapiens)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Saccharomyces cerevisiae)


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Homo sapiens)


name: PE is methylated to PC by PEMT (Dictyostelium discoideum)


name: acyltransferase activity, acyl groups converted into alkyl on transfer


name: "Acyl groups converted into alkyl groups on transfer"


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)


name: a ribonucleoside 5'-diphosphate + H(+) + sucrose => an NDP-alpha-D-glucose + D-fructose


name: RAC1,RAC2,RHOG activate PI3K (Xenopus tropicalis)


name: L-methionine transmembrane transporter activity


name: 24-methylidenelophenol + S-adenosyl-L-methionine => (Z)-24-ethylidenelophenol + H(+) + S-adenosyl-L-homocysteine


name: Inactive catalytic PP2B is activated by the binding of calmodulin (Homo sapiens)


name: 8,20-dihydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 8-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: H(+) + NADH + O2 + p-cumate = (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+)


name: SUMOylation of NR3C1 (GR) with SUMO1 (Danio rerio)


name: L-PRX:DRP:DGC:laminin-211 interacts with UTRN (Homo sapiens)


name: C20 sphinganine 1-phosphate + H2O <=> C20 sphinganine + phosphate


name: CYP1A2 hydroxylates AFB1 to AFM1 (Sus scrofa)


name: phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Bos taurus)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Danio rerio)


name: N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity


name: SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)


name: Inactivation of APC/C via CDC20 sequestration (Saccharomyces cerevisiae)


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O <=> 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate


name: Hemes bind to CLEC1B dimer (Canis familiaris)


name: Disassembly of COPII coated vesicle (Rattus norvegicus)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Mus musculus)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Sus scrofa)


name: H(+) + H2O2 + L-ascorbate => L-galactono-1,4-lactone + O2


name: A + 2 cob(II)alamin + 2 H(+) + 2 H2O <=> AH2 + 2 aquacob(III)alamin


name: CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Canis familiaris)


name: Mitochondrial FPGS-1 transforms THF to THFPG (Homo sapiens)


name: (2S,4S,5S)-2-amino-6-(3,4-dihydroxyphenyl)-4-hydroxy-5-(methylamino)hexanoyl-[peptidyl-carrier protein] + O2 => (2S,4S)-2-amino-4-[(3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl]-4-hydroxybutanoyl-[peptidyl-carrier protein] + H2O2


name: ATM dimer:PEX5 phosphorylates PEX5 (Bos taurus)