name: 2-hydroxy-5-carboxymethylmuconate semialdehyde + H2O + NAD(+) => (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate + 2 H(+) + NADH


name: GDP-alpha-D-rhamnose + NAD(+) <=> GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADH


name: Association of procollagen type XVII (Mus musculus)


name: PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: NADP(+) + octadecanoyl-CoA <=> (2E)-octadecenoyl-CoA + H(+) + NADPH


name: DOLK phosphorylates DCHOL to DOLP (Mus musculus)


name: 2-phosphoglycolate + H2O => glycolate + phosphate


name: a menaquinol(in) + dimethyl sulfoxide(out) = a menaquinone(in) + dimethyl sulfide(out) + H2O(out)


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Rattus norvegicus)


name: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + H(+) + S-adenosyl-L-homocysteine => 2-thio-N(6)-dimethylallyladenosine(37) in tRNA + S-adenosyl-L-methionine


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Saccharomyces cerevisiae)


name: (22S)-22-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose => a neolactoside nLc4Cer(d18:1(4E)) + H(+) + UDP


name: MTMR4 binds phosphorylated SMAD2/3 (Canis familiaris)


name: (2E)-hexadecenoyl-[ACP] + H(+) + NADH <=> hexadecanoyl-[ACP] + NAD(+)


name: 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Bos taurus)


name: Ca2+ influx through voltage gated Ca2+ channels (Caenorhabditis elegans)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + chloride + FADH2 + O2 => (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: Conjugation of SUMO1 to UBA2:SAE1 (Canis familiaris)


name: IL21 receptor JAK phosphorylation (Canis familiaris)


name: 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NADP(+) <=> 5alpha-cholest-8-en-3-one + CO2 + NADPH


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Homo sapiens)


name: PIAS1 SUMOylates DDX5 with SUMO2 (Mus musculus)


name: L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-methyl-5'-thioadenosine


name: a long-chain fatty acid(out) = a long-chain fatty acid(in)


name: Association of Cyclin A:Cdk2 with Cdh1 (Canis familiaris)


name: 1-octanoylglycerol + H2O = glycerol + H(+) + octanoate


name: (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = glyceollin III + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: (7S)-marmesin + O2 + reduced [NADPH--hemoprotein reductase] => acetone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + psoralen


name: H2O + prostaglandin F2alpha-CoA <=> CoA + H(+) + prostaglandin F2alpha


name: P2RX4,7 binds itself to form trimeric non-selective cation channels (Homo sapiens)


name: Cipro is oxidized to oxo-Cipro (Homo sapiens)


name: Cho transports from the extracellular space to the cytosol (Rattus norvegicus)


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Gallus gallus)


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA => 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: 5-dehydro-4-deoxy-D-glucarate => 2-hydroxy-3-oxopropanoate + pyruvate


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Homo sapiens)


name: peregrinol diphosphate => diphosphate + labd-13(16),14-diene-9-ol


name: The receptor:G-protein complex  binds GTP (Drosophila melanogaster)


name: RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Caenorhabditis elegans)


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Bos taurus)


name: 5,6-dihydroquinoline-2,5,6-triol + NAD(+) => H(+) + NADH + O2 + quinolin-2-ol


name: ZIP8 mediates zinc influx into cells (Mus musculus)


name: kanosamine + phosphate => D-kanosamine 6-phosphate + H2O


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Homo sapiens)


name: TRAF3 binds BAFFR:BAFF (Rattus norvegicus)


name: alcohol transmembrane transporter activity


name: 2-methyl-6-phytyl-1,4-benzene-1,4-diol + S-adenosyl-L-methionine = 2,3-dimethyl-6-phytylbenzene-1,4-diol + H(+) + S-adenosyl-L-homocysteine


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Bos taurus)


name: D-maltose + phosphate => beta-D-glucose 1-phosphate + D-glucose


name: ATP + H2O + L-valine(out) <=> ADP + H(+) + L-valine(in) + phosphate


name: N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine => 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate


name: 1-hydroxylimonen-2-one + H(+) + NADPH + O2 => 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Canis familiaris)


name: a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: (+)-sesamin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (+)-piperitol + O2 + reduced [NADPH--hemoprotein reductase]


name: LIPC dimer hydrolyses TAG to DAG and FA (Canis familiaris)


name: 5,6-dihydroxyindole + CO2 => D-dopachrome + H(+)


name: EHMT1:EHMT2 methylates IL6 promoter (Xenopus tropicalis)


name: alpha-maltopentaose + beta-maltose <=> alpha-maltohexaose + beta-D-glucose


name: ENPP6 hydrolyzes lysophosphatidylcholine (Canis familiaris)


name: GTP + L-glutamate + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> GDP + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n+1) + phosphate


name: 3'-phosphoadenylyl sulfate + desulfo-A47934 = A47934 + adenosine 3',5'-bisphosphate + H(+)


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Gallus gallus)


name: stigmasterol + UDP-alpha-D-glucose = H(+) + stigmasteryl 3-beta-D-glucoside + UDP


name: 2-hydroxyspirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 2,2-dihydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Interaction of PAK1 with Rac1-GTP (Caenorhabditis elegans)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Xenopus tropicalis)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Dictyostelium discoideum)


name: HEXB cleaves the terminal GalNAc from DS (Homo sapiens)


name: ATP + holo-[ACP] + tetradecanoate => AMP + diphosphate + tetradecanoyl-[ACP]


name: CDC42 and PIP2 bind WASL, activating it (Caenorhabditis elegans)


name: Endosome acidification (Dictyostelium discoideum)


name: Cross-linking of FCGRIIA with IgG-coated Ag (Gallus gallus)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O => 7-epi-alpha-eudesmol + diphosphate


name: Formation of lysyl-pyridinoline cross-links (Bos taurus)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Rattus norvegicus)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Mus musculus)


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Xenopus tropicalis)


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Sus scrofa)


name: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Rattus norvegicus)


name: CYP4F11 16-hydroxylates 3OH-PALM (Homo sapiens)


name: Removal of fibrillar collagen C-propeptides (Bos taurus)


name: ABCA5 transports CHOL from lysosomal lumen to cytosol (Bos taurus)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Homo sapiens)


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Gallus gallus)


name: D-glucarate(in) + H(+)(in) = D-glucarate(out) + H(+)(out)


name: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome (Canis familiaris)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Drosophila melanogaster)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Mus musculus)


name: Formation of dehydro-hydroxylysino-norleucine cross-links (Xenopus tropicalis)


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Mus musculus)


name: Transport of Antigen peptide in to ER (Sus scrofa)


name: DOCK180:ELMO binds CRK (Canis familiaris)


name: alpha,alpha-trehalose 6-phosphate + phosphate <=> beta-D-glucose 1-phosphate + D-glucose 6-phosphate


name: Phosphorylation of BRCA1-A complex at multiple sites by ATM (Mus musculus)


name: a ganglioside GT2 (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GT1c (d18:1(4E)) + H(+) + UDP


name: Formation of fatty acid synthase (FAS) dimer (Bos taurus)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Caenorhabditis elegans)


name: TTR:RBP:atROL binds to STRA6 receptor (Canis familiaris)


name: RHOGAPP190 activates GTP hydrolysis by RHO1:GTP (Drosophila melanogaster)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO4 (Mus musculus)


name: KDM1A is recruited to MYC and BCL2 genes (Gallus gallus)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Sus scrofa)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Gallus gallus)


name: GMPS dimer transforms 6TXMP to 6TGMP (Xenopus tropicalis)


name: 13-cis-retinol + NADP(+) <=> 13-cis-retinal + H(+) + NADPH


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Canis familiaris)


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Canis familiaris)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Canis familiaris)


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Sus scrofa)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Caenorhabditis elegans)


name: a (2E)-enoyl fatty acid + ATP + holo-[ACP] <=> a (2E)-enoyl-[ACP] + AMP + diphosphate


name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Homo sapiens)


name: 2 H(+)(in) + succinate(in) => 2 H(+)(out) + succinate(out)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Gallus gallus)


name: acetyl-CoA + N-terminal L-methionyl-[tubulin] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]


name: adenosine 3',5'-bisphosphate + H(+) + quercetin 3,3',7-trissulfate => 3'-phosphoadenylyl sulfate + quercetin 3,3'-bissulfate


name: (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + H(+) + NADPH


name: (S)-carnitine + ATP + CoA <=> (S)-carnitinyl-CoA + ADP + phosphate


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Xenopus tropicalis)


name: HK1 phosphorylates Mannose to Man6P (Mus musculus)


name: CO2 + resorcinol => 2,6-dihydroxybenzoate + H(+)


name: (2E,6E)-farnesyl diphosphate + H2O => (3R,6E)-nerolidol + diphosphate


name: chlorotoluron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3-(3-chloro-4-methylphenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Bos taurus)


name: NF2 binds PAK1 (Drosophila melanogaster)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Canis familiaris)


name: (1'S)-averantin + NADP(+) => H(+) + NADPH + norsolorinic acid


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) => 4-deoxy-6-O-methyl-L-threo-hex-4-enopyranuronate + [(1->4)-alpha-D-galacturonosyl methyl ester](n-1)


name: Formation of hRSV A dsRNA intermediate form (Homo sapiens)


name: trans-Golgi Network Coat Activation (Dictyostelium discoideum)


name: Dephosphorylation of JAK1 by SHP1 (Rattus norvegicus)


name: AP4 transports APP from trans-Golgi network to endosome lumen (Rattus norvegicus)


name: ATM recognizes H2AFX-Nucleosomes (Drosophila melanogaster)


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+) => [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate


name: GLTP transports GSL from plasma membrane to ER membrane (Plasmodium falciparum)


name: Interaction of SIGLEC14/15/16 and DAP12 (Sus scrofa)


name: Recruitment of XPA and release of CAK  (Schizosaccharomyces pombe)


name: H(+) + S-adenosyl-L-methionine <=> CO2 + S-adenosyl 3-(methylsulfanyl)propylamine


name: TFIIH-class transcription factor complex binding


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Bos taurus)


name: 2 H(+) + H2O + thiocyanate <=> carbonyl sulfide + NH4(+)


name: (+)-T-muurolol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: PIAS4 SUMOylates PPARA with SUMO1 (Xenopus tropicalis)


name: ISGylation of E2 conjugating enzymes (Drosophila melanogaster)


name: 2,6-dioxo-6-phenylhexa-3-enoate + H2O => 2-oxopent-4-enoate + benzoate + H(+)


name: 4-methylphenol + H2O + 2 oxidized [azurin] => 4-hydroxybenzyl alcohol + 2 H(+) + 2 reduced [azurin]


name: 3-(2-methylsulfanyl)ethylmalate => 2-(2-methylsulfanyl)ethylmaleate + H2O


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Dictyostelium discoideum)


name: Co(I)-[tetramethylammonium-specific corrinoid protein] + H(+) + methyl-coenzyme M => coenzyme M + methyl-Co(III)-[tetramethylammonium-specific corrinoid protein]


name: PLK1 phosphorylates FOXM1 (Rattus norvegicus)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Rattus norvegicus)


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Bos taurus)


name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Mus musculus)


name: 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + neopikromycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: HAS1,2,3 mediate the polymerization of HA (Rattus norvegicus)


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Sus scrofa)


name: L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H(+) + UDP


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Homo sapiens)


name: USP44 deubiquitinates CDC20 (Sus scrofa)


name: 3-O-methyl-L-dopa(in) + L-phenylalanine(out) => 3-O-methyl-L-dopa(out) + L-phenylalanine(in)


name: cytidine(967) in 16S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: ERK1/2 phosphorylates MSK1 (Drosophila melanogaster)


name: L-histidyl-[protein] + S-adenosyl-L-methionine => H(+) + N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine


name: AKR1B1 reduces Glc to D-sorbitol (Xenopus tropicalis)


name: ATP + L-seryl-[myosin light chain] => ADP + H(+) + O-phospho-L-seryl-[myosin light chain]


name: Elongation by POLH (Schizosaccharomyces pombe)


name: Elastin degradation by elastin-degrading extracellular proteinases (Bos taurus)


name: RAB43:GTP binds USP8NL (Caenorhabditis elegans)


name: (S)-2-ureidoglycine + carbamoyl phosphate <=> allantoate + H(+) + phosphate


name: PINK1 phosphorylates Ub on MOM proteins (Mus musculus)


name: N-tetradecanoyl-(2S)-hydroxyglycine => glyoxylate + tetradecamide


name: SCAI binds SRF:MKL1 (Drosophila melanogaster)


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Rattus norvegicus)


name: H2O + N-hexadecanoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: adenosine in rRNA + S-adenosyl-L-methionine => H(+) + N(6)-methyladenosine in rRNA + S-adenosyl-L-homocysteine


name: Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Canis familiaris)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Drosophila melanogaster)


name: ABCC1 transports cytosolic RCbl to extracellular region (Xenopus tropicalis)


name: 3'-phosphoadenylyl sulfate + alpha,alpha-trehalose <=> 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+)


name: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + H(+)


name: H(+) + H2O + NAD(+) + rifampicin para-naphthoquinone carboxamide => NADH + O2 + rifampicin


name: SLC2A5 transports fructose from extracellular region to cytosol (Canis familiaris)


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Caenorhabditis elegans)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Mus musculus)


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Mus musculus)


name: carminomycin + S-adenosyl-L-methionine => daunorubicin + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylation of MDM4 by ATM (Homo sapiens)


name: H2O + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] => H(+) + S-disulfanyl-L-cysteinyl-[SoxY protein] + sulfate


name: diphosphate + neryl diphosphate => dimethylallyl diphosphate + isopentenyl diphosphate


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Homo sapiens)


name: RAR:RXR binds SUMO-CRABP2:atRA (Canis familiaris)


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Canis familiaris)


name: (2S)-2-amino-3-oxobutanoate + H(+) => aminoacetone + CO2


name: acetyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] => CoA + myricetin 3-O-[(6-O-acetyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: Cleavage of hypoxanthine by MPG glycosylase (Plasmodium falciparum)


name: SCF(SKP2) polyubiquitinates RUNX2 (Gallus gallus)


name: glyoxylate + succinate => D-threo-isocitrate


name: cytidine(50) in tRNA + S-adenosyl-L-methionine => 5-methylcytidine(50) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Mus musculus)


name: (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycerol + H(+) => 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + H2O


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Bos taurus)


name: ABCC5 transports TPMP substrates from cytosol to extracellular region (Danio rerio)


name: AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine


name: Activated FGFR3 phosphorylates PLCG1 (Canis familiaris)


name: (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose <=> (20S)-ginsenoside F2 + H(+) + UDP


name: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)


name: gypsogenin + UDP-alpha-D-glucose => gypsogenin 28-beta-D-glucoside + UDP


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Sus scrofa)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Schizosaccharomyces pombe)


name: Formation of CRY:PER:Kinase complex (Homo sapiens)


name: IkB is ubiquitinated and degraded (Bos taurus)


name: SHC1 phosphorylation by ERBB2 heterodimers (Canis familiaris)


name: Receptors CXCR4 and 7 bind CXCL12 ligand (Rattus norvegicus)


name: The Ligand:GPCR:G12/13 complex dissociates (Sus scrofa)


name: MAT1A multimers transfer Ado from ATP to L-Met (Homo sapiens)


name: a 2'-deoxyribonucleoside 5'-phosphate + dGTP <=> a 2'-deoxyribonucleoside 5'-diphosphate + dGDP


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Rattus norvegicus)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Sus scrofa)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Homo sapiens)


name: H2O + trihexadecanoylglycerol <=> dihexadecanoylglycerol + H(+) + hexadecanoate


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O => 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + choline + H(+)


name: S-adenosyl-L-methionine + taxifolin => H(+) + S-adenosyl-L-homocysteine + taxifolin 4'-methyl ether


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Sus scrofa)


name: MPI isomerises Fru6P to Man6P (Danio rerio)


name: diphosphate + ent-sandaracopimara-8(14),15-diene => ent-copalyl diphosphate


name: THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 (Sus scrofa)


name: AH2 + trichloroethene => (Z)-1,2-dichloroethene + A + chloride + H(+)


name: HIPK2 phosphorylates TP53 (Drosophila melanogaster)


name: Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Xenopus tropicalis)


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + dimethylallyl diphosphate <=> (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + diphosphate


name: 3-methyl-1,2-didehydro-2,3-dihydrosqualene + S-adenosyl-L-methionine => 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + H(+) + S-adenosyl-L-homocysteine


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Plasmodium falciparum)


name: p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 (Homo sapiens)


name: Type B histone acetlytransferase complex acetylates histone H4 (Bos taurus)


name: D-serine(out) + L-glutamine(in) + Na(+)(in) => D-serine(in) + L-glutamine(out) + Na(+)(out)


name: AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Homo sapiens)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Homo sapiens)


name: (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O = (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + L-glutamate


name: 5'-pApG-3' + H2O = 5'-ApG-3' + phosphate


name: H2O + kynurenate + L-glutamate => 2-oxoglutarate + L-kynurenine


name: NEIL1 translocates to the nucleus (Sus scrofa)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA => a cardiolipin + CoA


name: Recognition and Binding of Core Promoter Elements by TFIID (Mus musculus)


name: Tenascins C, R, (X, N) bind lecticans (Canis familiaris)


name: (3R)-3-hydroxybutanoyl-CoA + H2O <=> (R)-3-hydroxybutanoate + CoA + H(+)


name: (3S)-3-aminobutanoyl-CoA + 2-oxoglutarate = acetoacetyl-CoA + L-glutamate


name: (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+)


name: SARS-CoV-1 3a tetramer induces potassium efflux (Homo sapiens)


name: 7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: thioacetamide S-oxide S-oxygenase activity


name: SeMet is converted to AdoSeMet by MAT (Xenopus tropicalis)


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)


name: SMOX-3 oxidises SPN to SPM (Drosophila melanogaster)


name: NIK autophosphorylates on T559 (Gallus gallus)


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Bos taurus)


name: guanosine(10) in tRNA + 2 S-adenosyl-L-methionine = 2 H(+) + N(2)-dimethylguanosine(10) in tRNA + 2 S-adenosyl-L-homocysteine


name: 19-hydroxy-11-deoxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 19-oxo-11-deoxycorticosterone + 2 H2O + 2 oxidized [adrenodoxin]


name: CoA + H(+) + N-hexacosanoyl-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + hexacosanoyl-CoA


name: POLD,POLE-mediated DNA strand displacement synthesis (Drosophila melanogaster)


name: ATP + cytidine(34) in tRNA(Ile2) + L-lysine <=> AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)


name: (9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphocholine <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: CBL-mediated ubiquitination of CIN85 (Bos taurus)


name: Recruitment of POLB to oxidatively damaged AP site (Rattus norvegicus)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Rattus norvegicus)


name: miR-19b microRNA binds PTEN mRNA (Homo sapiens)


name: Addition of nucleotides leads to transcript elongation (Rattus norvegicus)


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Rattus norvegicus)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Rattus norvegicus)


name: 3-dehydro-4-O-phospho-D-erythronate + H(+) = CO2 + dihydroxyacetone phosphate


name: 1D-myo-inositol 1,2-bisphosphate + H2O <=> 1D-myo-inositol 2-phosphate + phosphate


name: AH2 + formaldehyde + L-lysyl-[protein] => A + H2O + N(6)-methyl-L-lysyl-[protein]


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Drosophila melanogaster)


name: H(+)(out) + L-valine(in) <=> H(+)(in) + L-valine(out)


name: a neolactoside IV(3)-alpha-NeuNAc,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+) => a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + GDP-beta-L-fucose


name: 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Xenopus tropicalis)


name: ATP + glycerol => ADP + H(+) + sn-glycerol 3-phosphate


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Homo sapiens)


name: LMF1,2 transport LIPC dimer from ER lumen to extracellular region (Bos taurus)


name: Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 (Homo sapiens)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Drosophila melanogaster)


name: EHD proteins interact with Rabenosyn-5 (Mus musculus)


name: ROCK1,2 bind ROCKi (Drosophila melanogaster)


name: SUMOylation of TDG with SUMO1 (Danio rerio)


name: arginine + H2O => ornithine + urea [ARG2] (Dictyostelium discoideum)


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Mus musculus)


name: an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA => an anthocyanidin 3-O-beta-D-glucoside + malonyl-CoA


name: 4-methylsulfanyl-2-oxobutanoate + H(+) + NADH => (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NAD(+)


name: OSM,LIF,CTF1 receptor complex binds gp130 (Mus musculus)


name: SLC22A12 exchanges extracellular urate for cytosolic LACT (Mus musculus)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH => cholate + NADP(+)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Bos taurus)


name: Branching and elongation of mother and daughter filaments (Gallus gallus)


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Mus musculus)


name: methyl beta-D-glucoside 6-phosphate glucohydrolase activity


name: 3-methyl-L-tyrosine + H2O2 <=> 5-hydroxy-3-methyl-L-tyrosine + H2O


name: Phosphorylation and activation of Ezrin (Canis familiaris)


name: SUMOylation of NOP58 with SUMO2 (Dictyostelium discoideum)


name: RHOU binds effectors at the plasma membrane (Gallus gallus)


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Saccharomyces cerevisiae)


name: ADP + ADP <=> AMP + ATP [AK2] (Bos taurus)


name: alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ (Homo sapiens)


name: Association of procollagen type XVIII (Canis familiaris)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Homo sapiens)


name: a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine <=> a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Mus musculus)


name: Inactivation of Wee1 kinase (Saccharomyces cerevisiae)


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + 2 succinate


name: IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Canis familiaris)


name: Translocation of PKC theta to plasma membrane (Sus scrofa)


name: Activated NTRK2 binds FRS2 (Canis familiaris)


name: Spherical HDL binds membrane-associated free cholesterol and phospholipids (Mus musculus)


name: SCNN channels transport extracellular Na+ to cytosol (Canis familiaris)


name: HLCS biotinylates 6x(PCCA:PCCB) (Xenopus tropicalis)


name: RBKS phosphorylates ribose to R5P (Schizosaccharomyces pombe)


name: PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: a 3-oxoacyl-CoA + CO2 + CoA => an acyl-CoA + H(+) + malonyl-CoA


name: ESR1 binds ESR1 antagonists (Danio rerio)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)


name: pyridoxamine 5'-phosphate + pyruvate => D-alanine + pyridoxal 5'-phosphate


name: DHFR2 reduces FOLA to DHF (Dictyostelium discoideum)


name: SEC31:SEC13 and v-SNARE recruitment (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycerol => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Homo sapiens)


name: Digestion of linear starch (amylose) by extracellular amylase (Xenopus tropicalis)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Xenopus tropicalis)


name: cadaverine(in) + L-lysine(out) => cadaverine(out) + L-lysine(in)


name: CHEK1 phosphorylates E2F6 (Mus musculus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Xenopus tropicalis)


name: TBC1D20 binds RAB1:GTP (Plasmodium falciparum)


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)


name: arsenite(in) + ATP + H2O <=> ADP + arsenite(out) + H(+) + phosphate


name: (3S)-hydroxytetradecanoyl-CoA + NAD(+) <=> 3-oxotetradecanoyl-CoA + H(+) + NADH


name: Lsm1-7 Complex binds deadenylated mRNA (Rattus norvegicus)


name: STAT1,STAT3 binds PKR (Drosophila melanogaster)


name: (R)-carvone + H(+) + NADPH => (1S,5R)-carveol + NADP(+)


name: CoA + H(+) + N-tetracosanoylsphinga-(4E,8Z)-dienine => sphinga-(4E,8Z)-dienine + tetracosanoyl-CoA


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Mus musculus)


name: Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K (Homo sapiens)


name: Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Danio rerio)


name: a globoside GalGb4Cer (d18:1(4E)) + GDP-beta-L-fucose <=> a globoside Globo-H (d18:1(4E)) + GDP + H(+)


name: (S)-benzodiazepinedione + dimethylallyl diphosphate = (2S,3R,11S)-aszonalenin + diphosphate


name: DHNTP is dephosphorylated by PTPS to PTHP (Caenorhabditis elegans)


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Drosophila melanogaster)


name: alpha-L-iduronyl-(1->3)-N-acetyl-D-6-sulfogalactosamine + N-acetyl-D-6-sulfogalactosamine => H2O + N-acetyl-beta-D-6-sulfogalactosaminyl-(1->4)-alpha-L-iduronyl-(1->3)-N-acetyl-D-6-sulfogalactosamine


name: a ganglioside GD1a + H2O <=> a ganglioside GM1 + N-acetylneuraminate


name: H(+) + NADH + perillyl aldehyde => NAD(+) + perillyl alcohol


name: Activation of Ca2+ activated Potassium channels with large conductance (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: p-STAT1 dissociates from IL6ST:IL6ST (Homo sapiens)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CTP + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: VMAT1/2 can mediate the transport of biogenic amines (Schizosaccharomyces pombe)


name: 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity


name: VD3 translocates from extracellular region to ER membrane (Homo sapiens)


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Plasmodium falciparum)


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: Latent TGF-beta-3 binds integrins (Danio rerio)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Saccharomyces cerevisiae)


name: 4 CO2 + 4 CoA + 4 H2O + 8 NADP(+) + tetramethylated-mycocerosoyl-[mycocerosate synthase] => 4 (R)-methylmalonyl-CoA + 12 H(+) + long-chain fatty acyl-[mycocerosate synthase] + 8 NADPH


name: SARS-CoV-2 N binds to G3BP1,G3BP2 (Homo sapiens)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Mus musculus)


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Rattus norvegicus)


name: L-alanine(out) + L-glutamine(in) + Na(+)(out) = L-alanine(in) + L-glutamine(out) + Na(+)(in)


name: NEXT3 is cleaved to produce NICD3 (Mus musculus)


name: CMKLR1 binds Resolvin E1 (Xenopus tropicalis)


name: alpha-D-glucose 1-phosphate + 2 H(+) + UMP => H2O + UDP-alpha-D-glucose


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Rattus norvegicus)


name: Formation of NR-NCOR Corepressor Complex (Caenorhabditis elegans)


name: Digestion of linear starch (amylose) by extracellular amylase (Sus scrofa)


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Rattus norvegicus)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate => 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O


name: Formation of cap binding complex (CBC) (Bos taurus)


name: MLCL is acylated to CL by HADH (IM) (Homo sapiens)


name: a 1,2-diacyl-sn-glycerol + H(+) + phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O


name: Caspase-7 translocates to the nucleus (Danio rerio)


name: EPH:EFN tetramers oligomerise (Rattus norvegicus)


name: 2-oxoglutarate + 3-methylundecanoyl-CoA + O2 <=> 2-hydroxy-3-methylundecanoyl-CoA + CO2 + succinate


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Danio rerio)


name: PTGS2 dimer oxidises DHA to 13-HDHA (Bos taurus)


name: (3S)-2-oxo-3-phenylbutanoate + L-glutamate => (2S,3S)-3-methylphenylalanine + 2-oxoglutarate


name: an N-(fatty acyl)-L-asparagine + H2O => a fatty acid + L-asparagine


name: (+)-malbrancheamide D + FADH2 => (+)-malbrancheamide B + bromide + FAD + 2 H(+)


name: (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O <=> (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose


name: 4-pyridoxate + H(+) + H2O2 => H2O + O2 + pyridoxal


name: H2O + S-sulfosulfanyl-L-cysteinyl-[SoxY protein] => H(+) + S-sulfanyl-L-cysteinyl-[SoxY protein] + sulfate


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Danio rerio)


name: D-maltoheptaonate + H(+) => D-maltoheptaono-1,5-lactone + H2O


name: argininosuccinate <=> fumarate + arginine (Xenopus tropicalis)


name: Zinc is an agonist of GPR39 (Gallus gallus)


name: ALDH1A1 oxidises GA to DGA (Rattus norvegicus)


name: (R)-demethyl-4-deoxygadusol + H(+) + H2O + phosphate => D-sedoheptulose 7-phosphate


name: 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-(9Z-octadecenoyl)-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine


name: PI3K associates with phosphorylated GAB2 (Xenopus tropicalis)


name: ST8SIA5 transfers Neu5Ac to gangliosides (Rattus norvegicus)


name: oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: Recruitment of Rad17-RFC complex to DNA (Rattus norvegicus)


name: p-STAT1dimer:KPNA1 binds KPNB1 (Drosophila melanogaster)


name: acetyl-CoA + hexan-1-ol <=> CoA + hexyl acetate


name: D-glucose + D-glucose 6-phosphate => 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O


name: ITSN1 exchanges GTP for GDP on CDC42, activating it (Homo sapiens)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Mus musculus)


name: (2S)-3-sulfolactaldehyde + dihydroxyacetone phosphate => 6-deoxy-6-sulfo-D-fructose 1-phosphate


name: Activation of TAK1 complex bound to pUb-TRAF6 (Mus musculus)


name: 3-methylphenol + CO2 => 6-methylsalicylate + H(+)


name: AH2 + cholesterol + O2 = 25-hydroxycholesterol + A + H2O


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Xenopus tropicalis)


name: Homocysteine is degraded to oxobutanoate and H2S (Rattus norvegicus)


name: CO2 + 2 H2O + NAD(+) + proviolacein => 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate


name: Phosphorylation of LIMK-1 by PAK (Mus musculus)


name: (+)-corvol ether B + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: TNKS and TNKS2 PARylate PTEN (Sus scrofa)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Bos taurus)


name: Thrombin-activated PARs:Gq (active) dissociate (Gallus gallus)


name: 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine => 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: gibberellin A12 16alpha,17 epoxidase activity


name: (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+) => 2-oxoglutarate + dodecanoyl-CoA + H2O


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Sus scrofa)


name: Formation of DSIF complex  (Homo sapiens)


name: (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + NADP(+)


name: Proton-coupled di- and tri-peptide cotransport (Bos taurus)


name: LYZ binds bacterial peptidoglycan (Gallus gallus)


name: ASIC3 channel blockers bind ASIC3 trimer (Caenorhabditis elegans)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-galactosamine = N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate <=> (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate


name: Transphosphorylation of pLIMK1 (Sus scrofa)


name: dimethylallyl diphosphate = diphosphate + isoprene


name: H2O + S-succinylglutathione = glutathione + H(+) + succinate


name: ULK1 phosphorylates Beclin-1 (Caenorhabditis elegans)


name: NOTCH2 gene transcription (Homo sapiens)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)


name: TP53 stimulates PRDM1 expression (Homo sapiens)


name: Endocytosis of TRAM (TICAM2) (Bos taurus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Xenopus tropicalis)


name: Formation of tonofilament bundles (Canis familiaris)


name: geranylgeranyl diphosphate + H2O = cyclooctat-9-en-7-ol + diphosphate


name: I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol (Drosophila melanogaster)


name: Parenchymal atROL translocates to HSCs (Xenopus tropicalis)


name: androsterone + NAD(+) => 5alpha-androstan-3,17-dione + H(+) + NADH


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Drosophila melanogaster)


name: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) <=> 3-hydroxy-2-methylpyridine-5-carboxylate + CO2


name: H(+) + NADH + NH4(+) + propanal => H2O + NAD(+) + propylamine


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Mus musculus)


name: dGTP + pyruvate => dGDP + H(+) + phosphoenolpyruvate


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Rattus norvegicus)


name: NADP(+) + neomorphine => H(+) + NADPH + neomorphinone


name: Activated MAPKs phosphorylate MAP2K1 (Saccharomyces cerevisiae)


name: Proton-coupled di- and tri-peptide cotransport (Canis familiaris)


name: morphine + NAD(+) = H(+) + morphinone + NADH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: 2-dehydro-D-gluconate + H(+) + NADPH => D-gluconate + NADP(+)


name: H2O + O-phospho-L-threonine <=> L-threonine + phosphate


name: p-Y705-STAT3 binds p-Y693-STAT4 (Canis familiaris)


name: Degradation multiubiquitinated Cyclin A (Bos taurus)


name: RAC1 translocates to the endoplasmic reticulum membrane (Danio rerio)


name: cytidine(3782) in 28S rRNA + S-adenosyl-L-methionine => 5-methylcytidine(3782) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: CARKD dehydrates S-NAD(P)HX to NADPH (Caenorhabditis elegans)


name: Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA (Homo sapiens)


name: H2O + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine <=> acetate + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine


name: ALOX5 oxidises DHA to 7-HDHA (Bos taurus)


name: p-VAV family:PIP3 binds RAC1:GDP (Xenopus tropicalis)


name: Corticotropin cleavage from POMC (Danio rerio)


name: A + H2O + N(6)-methyl-L-lysyl-[protein] <=> AH2 + formaldehyde + L-lysyl-[protein]


name: a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine


name: a 1-acyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = a 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: genistein 7-O-beta-D-glucoside + H2O <=> beta-D-glucose + genistein


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Homo sapiens)


name: CHUK, IKBKB and IKBKG form IKK complex (Sus scrofa)


name: Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Canis familiaris)


name: (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 oxidized [adrenodoxin]


name: Endonucleolytic RISC hydrolyzes target RNAs (Rattus norvegicus)


name: ERCC8 (CSA) binds stalled RNA Pol II (Homo sapiens)


name: indole-3-ethanol + NADP(+) => H(+) + indole-3-acetaldehyde + NADPH


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Mus musculus)


name: 2 L-tyrosyl-tRNA(Tyr) <=> cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)


name: SLC29A1 transports RBV from cytosol to extracellular region (Dictyostelium discoideum)


name: Digestion of branched starch (amylopectin) by extracellular amylase (Bos taurus)


name: hexanoyl-CoA + tyramine <=> CoA + H(+) + N-hexanoyltyramine


name: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 <=> 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)


name: AcK-NFE2L2 binds the ABCC3 gene (Homo sapiens)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Rattus norvegicus)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Homo sapiens)


name: ATP + eicosanoate + H(+) <=> diphosphate + icosanoyl-AMP


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Caenorhabditis elegans)


name: Formation of ADAR2  homodimer (Xenopus tropicalis)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Caenorhabditis elegans)


name: Formation of Cyclin B:Cdc2 complexes (Homo sapiens)


name: Association of procollagen type VII (Caenorhabditis elegans)


name: cyclobis-(1->3)-alpha-D-isomaltosyl + 2 H2O => 2 isomaltose


name: (2E,6E,10E)-geranylgeranyl diphosphate = (-)-cyatha-3,12-diene + diphosphate


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Bos taurus)


name: SENP1,2,5 proteolytically process SUMO1 (Gallus gallus)


name: 2 Fe(III)-[cytochrome b5] + H2O + N-acyl-4-hydroxyeicosasphinganine => an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: SLC22A1 transports Cipro into renal cell (Danio rerio)


name: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine => an N(6)-methyl-2'-O-methyladenosine in U2 snRNA + H(+) + S-adenosyl-L-homocysteine


name: Formation of the CE:GMP intermediate complex (Xenopus tropicalis)


name: H(+) + N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine => N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine


name: (+)-minovincinine + acetyl-CoA = (+)-echitovenine + CoA


name: SHP2 phosphatase binds CTLA-4 (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate + H2O => (3S,6E)-nerolidol + diphosphate


name: 2 H(+)(out) + ubiquinol-8 => 2 H(+)(in) + H2 + ubiquinone-8


name: 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA => a 2-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA


name: CK2 phosphorylates condensin I subunits (Sus scrofa)


name: ent-sandaracopimara-8(14),15-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-sandaracopimaradien-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADP and Pi bind to ATPase (Homo sapiens)


name: SCF(SKP2) polyubiquitinates RUNX2 (Caenorhabditis elegans)


name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Drosophila melanogaster)


name: DELE1(143-515) binds EIF2AK1 (HRI) (Xenopus tropicalis)


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O => a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Mus musculus)


name: acetate + cadaverine => H2O + N-acetylcadaverine


name: adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate => adenosylcob(III)alamin 5'-phosphate + GMP + H(+)


name: beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose => alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: 3-phosphonopyruvate + H2O = H(+) + phosphate + pyruvate


name: Ubiquitination of Cyclin D1 (Homo sapiens)


name: HDACs deacetylate p-STAT3 dimers (Xenopus tropicalis)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Sus scrofa)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Homo sapiens)


name: [DsrC protein]-dithiol + 2 a quinone + 2 H(+) + hydrogen sulfide = [DsrC protein]-trisulfide + 2 a quinol + H(+)


name: H2O + N(6)-acetyl-L-lysyl-[histone] => acetate + L-lysyl-[histone]


name: H2O + sn-glycerol 3-phosphocholine => glycerol + H(+) + phosphocholine


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Canis familiaris)


name: dibenzothiophene 5,5-dioxide + 2 FMN + 2 H(+) + 2 H2O => dibenzothiophene + 2 FMNH2 + 2 O2


name: D-ribulose 5-phosphate + H(+) + NADPH => D-ribitol 5-phosphate + NADP(+)


name: chlordecone alcohol + NADP(+) => chlordecone + H(+) + NADPH


name: CYP17A1 cleaves 17aHPREG to DHA (Danio rerio)


name: GBA2 hydrolyzes GlcCer (plasma membrane) (Mus musculus)


name: histone H3K122 acetyltransferase activity


name: H2O + NAD(+) + phosphonoacetaldehyde <=> 2 H(+) + NADH + phosphonoacetate


name: ESR1 binds ESR1 agonists (Drosophila melanogaster)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Gallus gallus)


name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Rattus norvegicus)


name: H(+) + N(6)-(dimethylallyl)adenosine 5'-phosphate + NADPH + O2 <=> 9-ribosyl-trans-zeatin 5'-phosphate + H2O + NADP(+)


name: Aquaporin-1 passively transports water out of cell (Plasmodium falciparum)


name: H(+) + L-aspartate => beta-alanine + CO2


name: inositol phosphorylceramide mannosyltransferase activity


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: 4-(trimethylamino)butanal + H2O + NAD(+) => 4-(trimethylamino)butanoate + 2 H(+) + NADH


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Bos taurus)


name: 2 flaviolin + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 3,3'-biflaviolin + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Sus scrofa)


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)


name: (2E)-butenoyl-CoA + H2O => 3-hydroxybutanoyl-CoA


name: (2E)-butenoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin] => butanoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2-hydroxycyclohexan-1-one + NADPH + O2 <=> 6-oxohexanoate + H2O + NADP(+)


name: GUSB tetramer hydrolyses (HA)2 (Xenopus tropicalis)


name: Activated PKC phosphorylates SHC1 (Sus scrofa)


name: H(+) + H2O + N-benzyloxycarbonyl-L-leucine => benzyl alcohol + CO2 + L-leucine


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Rattus norvegicus)


name: NAD(+) + phosphate = ADP-alpha-D-ribose 1''-phosphate + H(+) + nicotinamide


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Rattus norvegicus)


name: TFAM binds to mitochondrial promoters (Gallus gallus)


name: AH2 + all-trans-retinol => A + all-trans-13,14-dihydroretinol


name: cytidine(1404) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1404) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: L-aspartate + NADPH + O2 => H2O + N-hydroxy-L-aspartate + NADP(+)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] => (13R)-hydroxy-(9Z,11E)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Homo sapiens)


name: Tryptophan is hydroxylated (Canis familiaris)


name: H2O + octanoyl-[ACP] => H(+) + holo-[ACP] + octanoate


name: PI3 binds the bacterial surface (Sus scrofa)


name: 3-oxoadipyl-CoA + succinate => 3-oxoadipate + succinyl-CoA


name: L-glutamyl-[protein] + S-adenosyl-L-methionine => [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine


name: p62 recruits an atypical PKC (Sus scrofa)


name: Association of procollagen type XI (Canis familiaris)


name: BTN2A2 binds T cell surface (Canis familiaris)


name: AURKA phosphorylates PLK1 (Homo sapiens)


name: Exocytosis of platelet dense granule content (Danio rerio)


name: GDIs block activation of RHOC (Homo sapiens)


name: Dopa is decarboxylated to dopamine (Bos taurus)


name: PLEKHA3,8 bind PI4P, ARF1 (Mus musculus)


name: Alternative endo-mannosidase I route (Xenopus tropicalis)


name: 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine => anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine


name: dimethylallyl diphosphate <=> diphosphate + isoprene


name: 4-hydroxy-1-pyrroline-2-carboxylate + H(+) + H2O <=> 2,5-dioxopentanoate + NH4(+)


name: NEDD4L ubiquitinates SMAD2/3 (Caenorhabditis elegans)


name: PD-1 binds B7DC and B7H1 (Gallus gallus)


name: 2-hydroxy-2-methylpropanoate + L-lysyl-[protein] => H2O + N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein]


name: GAPDH tetramers reduce 1,3BPG to GA3P (Sus scrofa)


name: H2O + histamine + O2 => H2O2 + imidazole-4-acetaldehyde + NH4(+)


name: Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Homo sapiens)


name: ATP + GTP => AMP + guanosine 3'-diphosphate 5'-triphosphate


name: deoxyadlupulone + dimethylallyl diphosphate => adlupulone + diphosphate + H(+)


name: MAD2 associates with the Mad1 kinetochore complex (Gallus gallus)


name: isolithocholate + NADP(+) => 3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: (S)-reticuline + S-adenosyl-L-methionine <=> (S)-tembetarine + H(+) + S-adenosyl-L-homocysteine


name: Thrombin-activated PARs:Gq (active) dissociate (Bos taurus)


name: MAPKs phosphorylate ETS1 and ETS2 (Canis familiaris)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2 = 2-dehydro-D-glucose + glycine + H2O2


name: beta,beta digalactosyldiacylglycerol galactosyltransferase activity


name: chloride(in) + 2 Na(+)(in) + O-propanoyl-(R)-carnitine(in) => chloride(out) + 2 Na(+)(out) + O-propanoyl-(R)-carnitine(out)


name: 4-thiouridine 5'-phosphate + ADP + H(+) => 4-thiouridine + ATP


name: (2E)-pentadecenoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + oxidized [electron-transfer flavoprotein] + pentadecanoyl-CoA


name: (2'R)-atrovenetin + S-adenosyl-L-methionine = deoxyherqueinone + H(+) + S-adenosyl-L-homocysteine


name: (2E,4Z)-2-hydroxy-6-oxononadienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H(+) + succinate


name: AMOT proteins bind WWTR1 (TAZ) (Sus scrofa)


name: 1-(ergostan-3beta-yl)-L-aspartate + tRNA(Asp) => ergosterol + L-aspartyl-tRNA(Asp)


name: Squalene is oxidized to its epoxide (Saccharomyces cerevisiae)


name: PIP3 recruits PDK1 and AKT to the membrane (Schizosaccharomyces pombe)


name: Sulfate is exported to the cytosol in exchange for dicarboxylate (Canis familiaris)


name: Furin cleaves pro-GAS6 to GAS6 (Gallus gallus)


name: p-Y389,400-RUFY1 binds PI3P (Canis familiaris)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Sus scrofa)


name: ATP + CoA + propanoate = AMP + diphosphate + propanoyl-CoA


name: TNF-mediated dimerization of procaspase-8 (Rattus norvegicus)


name: H2O + methyl acetate <=> acetate + H(+) + methanol


name: Platelet-derived TREM-1 ligand binds to TREM-1 (Rattus norvegicus)


name: alpha-D-glucose 1-phosphate + H2O <=> D-glucose + phosphate


name: PEX7 binds cargo proteins containing PTS2 (Bos taurus)


name: NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP (Plasmodium falciparum)


name: CTP(out) + GMP(in) <=> CTP(in) + GMP(out)


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Rattus norvegicus)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Drosophila melanogaster)


name: SLC25A18,22 import L-Glu, H+ (Mus musculus)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Drosophila melanogaster)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Drosophila melanogaster)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Danio rerio)


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Bos taurus)


name: PSAP(195-273) forms a dimer (Drosophila melanogaster)


name: 2-oxoglutarate + FADH2 => (S)-2-hydroxyglutarate + FAD + H(+)


name: glutathione + 2 H(+) + sulfite => H2O + O2 + S-sulfanylglutathione


name: dADP + H2O = 2'-deoxyadenosine + diphosphate


name: COX15 transforms heme O to heme A (Drosophila melanogaster)


name: (8S)-annullatin E + dimethylallyl diphosphate <=> (8S)-annullatin J + diphosphate


name: C4b binds to target cell surface (Gallus gallus)


name: LIG1 bound to POLB ligates SSB (Canis familiaris)


name: choline + H(+) + NADH + O2 <=> glycolaldehyde + H2O + NAD(+) + trimethylamine


name: fructose 5-dehydrogenase (NADP+) activity


name: diacetyl + H(+) + NADH => (S)-acetoin + NAD(+)


name: Active PLC-gamma1 dissociates from EGFR (Homo sapiens)


name: Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen (Xenopus tropicalis)


name: (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose = (20S)-ginsenoside F2 + H(+) + UDP


name: an alcohol + D-glucuronate => a beta-D-glucuronoside + H2O


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Homo sapiens)


name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Xenopus tropicalis)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Sus scrofa)


name: 2 3-octadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol) <=> 3-octadecanoyl-sn-glycero-1-phospho-(3'-octadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)


name: ITP + N-acetyl-D-glucosamine => H(+) + IDP + N-acetyl-D-glucosamine 6-phosphate


name: COMT transfers Met to DOPAC to form HVA (Sus scrofa)


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Rattus norvegicus)


name: diphosphate + L-serine => H(+) + O-phospho-L-serine + phosphate


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Mus musculus)


name: Two NPFF receptors can bind neuropeptide FF (Rattus norvegicus)


name: H2O + rhodopin => 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen


name: "With reduced pteridine as one donor, and incorporation of one atom of oxygen"


name: (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH => (1R,2S)-ephedrine + NAD(+)


name: ADP + H(+) + phosphate + pravastatin(out) => ATP + H2O + pravastatin(in)


name: 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-methionine = 3-methoxy,4-hydroxy-5-all-trans-polyprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: D-nopaline + H2O + NADP(+) <=> 2-oxoglutarate + H(+) + L-arginine + NADPH


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Bos taurus)


name: Hydroperoxyl enters the bacterium (Homo sapiens)


name: HIPK2 phosphorylates TP53 (Canis familiaris)


name: 1-acyl LPE is acylated to PE by LPEAT (Dictyostelium discoideum)


name: PPP1CC dephosphorylates PLK1 (Sus scrofa)


name: H2O + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] = H(+) + S-disulfanyl-L-cysteinyl-[SoxY protein] + sulfate


name: TRNT1 polymerizes CCA at the 3' end of pre-tRNA (Homo sapiens)


name: cGMP-inhibited cyclic-nucleotide phosphodiesterase activity


name: SLC22A1 transports Cipro into hepatic cell (Drosophila melanogaster)


name: (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+)


name: (omega-1)-methyl-(3R)-hydroxy-fatty acyl-CoA + NADP(+) = (omega-1)-methyl-3-oxo-fatty acyl-CoA + H(+) + NADPH


name: p-T774-PKN1 phosphorylates CDC25C (Mus musculus)


name: acetyl-CoA + tyramine = CoA + H(+) + N-acetyltyramine


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Xenopus tropicalis)


name: sphinganine + tetradecanoyl-CoA <=> CoA + H(+) + N-(tetradecanoyl)-sphinganine


name: 2xTPK1:Mg2+ phosphorylates THMN (Drosophila melanogaster)


name: Autophosphorylation of SRC (Danio rerio)


name: 5alpha-cholest-8-en-3beta-ol + NADP(+) => 5alpha-cholest-8,14-dien-3beta-ol + H(+) + NADPH


name: (20S)-protopanaxadiol + O2 + reduced [NADPH--hemoprotein reductase] <=> (20S)-protopanaxatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CMP-5'-(3-aminopropyl)phosphonate + NADPH + O2 <=> CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate + H2O + NADP(+)


name: 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Xenopus tropicalis)


name: (2E)-geraniol + phosphate => (2E)-geranyl phosphate + H2O


name: glycine + 2 H(+) + phosphate => (1R)-(2-amino-1-hydroxyethyl)phosphonate + O2


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Caenorhabditis elegans)


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Drosophila melanogaster)


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-O-hexadecyl-sn-glycero-3-phosphocholine + H(+)


name: D-allo-threonine + H2O + O2 => (R)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+)


name: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Canis familiaris)


name: a 2'-deoxycytidine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + O2


name: CHRM4 binds CHRM4 antagonists (Gallus gallus)


name: NPHP4 protein binds LATS proteins (Gallus gallus)


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: a (3R)-3-isocyanyl-fatty acid + 3 CO2 + 2 H2O + 2 succinate => 2 2-oxoglutarate + a (3R)-3-[(carboxymethyl)amino]fatty acid + 2 O2


name: SCD5 desaturates ST-CoA to OLE-CoA (Schizosaccharomyces pombe)


name: PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Sus scrofa)


name: 3'-phosphoadenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-bisphosphate + H(+) + quercetin 3,3'-bissulfate


name: NPC1L1-mediated phytosterol uptake (Homo sapiens)


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)


name: GUK1 phosphorylates 6TGMP to 6TGDP (Schizosaccharomyces pombe)


name: 25-substituted-cholesterol + D-glucose => 25-substituted-cholesteryl beta-D-glucoside + H2O


name: 4-oxo-L-proline + H(+) + NADH => cis-4-hydroxy-L-proline + NAD(+)


name: 4-hydroxybenzoate + ATP + CoA = 4-hydroxybenzoyl-CoA + AMP + diphosphate


name: RABGGTA and RABGGTB bind (Schizosaccharomyces pombe)


name: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine => 2'-O-methyladenosine(1067) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: SYK autophosphorylates at the activated BCR (Sus scrofa)


name: Phosphorylation of complexed TSC2 by PKB (Rattus norvegicus)


name: 3-oxopropanoate + H2O + NAD(+) <=> 2 H(+) + malonate + NADH


name: Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Danio rerio)


name: Dissociation of p-T,Y-MAPK3:MAP2K1 (Homo sapiens)


name: a 2'-deoxyadenosine in single-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in single-stranded DNA + O2


name: glycine betaine + H(+) + H2O2 => betaine aldehyde + H2O + O2


name: 5-aminolevulinic acid transmembrane transporter activity


name: Histone acetyltransferases are recruited to the TFF1 gene (Sus scrofa)


name: WWTR1 (TAZ) binds ZO-2 (TJP2) (Gallus gallus)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Danio rerio)


name: H2O + tetrathionate => H(+) + sulfate + sulfur + thiosulfate


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Homo sapiens)


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Drosophila melanogaster)


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Canis familiaris)


name: L-dihydroanticapsin + NAD(+) <=> H(+) + L-anticapsin + NADH


name: TCR binds microbial lipid-based antigen via CD1 (Rattus norvegicus)


name: FAD(out) + NAD(+)(in) = FAD(in) + NAD(+)(out)


name: L-aspartate(in) + L-glutamine(out) = L-aspartate(out) + L-glutamine(in)


name: Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Sus scrofa)


name: acetyl-CoA + N-terminal L-seryl-[histone H2A] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H2A]


name: indole-3-pyruvate + L-kynurenine = H2O + kynurenate + L-tryptophan


name: NAD(+) + taurocholate <=> 7-oxo-taurodeoxycholate + H(+) + NADH


name: Acidification of Tf:TfR1 containing endosome (Canis familiaris)


name: 3-phosphoglycerate <=> 2-phosphoglycerate (Gallus gallus)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Danio rerio)


name: Interleukin-1 receptor type 2 binds Interleukin 1 (Sus scrofa)


name: 4-pyridoxate + A <=> 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + AH2


name: ATP + L-glutamate + tRNA(Glu) <=> AMP + diphosphate + L-glutamyl-tRNA(Gln)


name: Tenascins C, R, (X, N) bind lecticans (Sus scrofa)


name: Phosphorylation of MEF2 proteins by p38 (Dictyostelium discoideum)


name: Cleavage of ERBB4m80 by gamma-scretase complex (Caenorhabditis elegans)


name: FOLR2 transports FOLA from extracellular region to cytosol (Mus musculus)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Caenorhabditis elegans)


name: ARSA removes sulfate from SM3 (Schizosaccharomyces pombe)


name: AH2 + cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + 2 S-adenosyl-L-methionine = 5'-deoxyadenosine + A + cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: Misspliced GSK3beta mutants stabilize beta-catenin levels (Homo sapiens)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Danio rerio)


name: Tropoelastin forms aggregate globules (Canis familiaris)


name: RNF20:RNF40 monoubiquitinates Histone H2B (Xenopus tropicalis)


name: ADP-alpha-D-glucose + sn-glycerol 3-phosphate = 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + ADP + H(+)


name: (indol-3-yl)acetate + ATP + CoA <=> (indol-3-yl)acetyl-CoA + AMP + diphosphate


name: [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + ATP + H(+) => [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + diphosphate


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Mus musculus)


name: H2O + hexadecanoate ester = an aliphatic alcohol + H(+) + hexadecanoate


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Rattus norvegicus)


name: PP2A demethylation by PPME1 (Saccharomyces cerevisiae)


name: SMPD1 hydrolyzes SPHM (Dictyostelium discoideum)


name: a ganglioside GD1b (d18:1(4E)) + H2O <=> a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate


name: Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + FAD + H(+) <=> (2E,9Z)-octadecadienoyl-CoA + FADH2


name: 17beta-estradiol + AH2 + O2 <=> 6beta-hydroxyestradiol-17beta + A + H2O


name: ATP + citrate + CoA <=> (3S)-citryl-CoA + ADP + phosphate


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Drosophila melanogaster)


name: L-selenocysteinyl-tRNA(Sec) + phosphate => H(+) + L-seryl-tRNA(Sec) + selenophosphate


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + desulfo-A47934 => A47934 + adenosine 3',5'-bisphosphate + H(+)


name: Beta-defensins 4A and 103 bind CCR2 (Gallus gallus)


name: formate + 2 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) => CO2 + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Netrin-4 binds DCC/UNC5A (Gallus gallus)


name: 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + CO2 + S-adenosyl-L-methionine => 2 H(+) + S-adenosyl-L-homocysteine + wybutosine(37) in tRNA(Phe)


name: Rheb in the MTORC1 complex hydrolyses GTP (Canis familiaris)


name: 2 Fe(III)-[cytochrome c2] + NADPH <=> 2 Fe(II)-[cytochrome c2] + H(+) + NADP(+)


name: DSCAM/DSCAML1 homodimerization (Rattus norvegicus)


name: 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+) => D-tyrosine + H2O + O2


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Dictyostelium discoideum)


name: ABC-type quaternary ammonium compound transporting activity


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Drosophila melanogaster)


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Sus scrofa)


name: H2O + N-octanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-octanoyl ethanolamine


name: UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Homo sapiens)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Homo sapiens)


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Mus musculus)


name: UDP-alpha-D-galactose(out) + UDP-N-acetyl-alpha-D-glucosamine(in) => UDP-alpha-D-galactose(in) + UDP-N-acetyl-alpha-D-glucosamine(out)


name: 2'-hydroxy-2,3-dihydrodaidzein + NADP(+) => 2'-hydroxydaidzein + 2 H(+) + NADPH


name: 3-(hydrohydroxyphosphoryl)pyruvate + acetyl-CoA + H2O = CoA + H(+) + phosphinomethylmalate


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Xenopus tropicalis)


name: PAO:FAD oxidises NASPM to PTCN (Caenorhabditis elegans)


name: p-T,Y MAPK dimers translocate to nucleus (Caenorhabditis elegans)


name: ligase activity, forming phosphoric ester bonds


name: dodecanoyl-CoA + L-seryl-[protein] <=> CoA + O-dodecanoyl-L-seryl-[protein]


name: Formation of P-TEFb complex (Dictyostelium discoideum)


name: Growth hormone binds the growth hormone receptor (Mus musculus)


name: 2 A + hydroxylamine + NH4(+) <=> 2 AH2 + H(+) + H2O + N2


name: 2,3-dioxo-L-gulonate(in) + Na(+)(in) <=> 2,3-dioxo-L-gulonate(out) + Na(+)(out)


name: H(+) + leukotriene E4 + NADPH + O2 => 20-hydroxy-leukotriene E4 + H2O + NADP(+)


name: D-maltopentaonate + H(+) => D-maltopentaono-1,5-lactone + H2O


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: MECP2 is phosphorylated at S423 (Homo sapiens)


name: lysophosphatidic acid phosphatase activity


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Caenorhabditis elegans)


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O


name: CYPs hydroxylate DHA to 14(R)-HDHA (Bos taurus)


name: PI3K produces PIP3 and other phosphatidyl inositides (Sus scrofa)


name: WNT ligands traffic to the plasma membrane (Xenopus tropicalis)


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP(+) <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + H(+) + NADPH


name: 5-hydroxy-3-methyl-O-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine => 5-hydroxy-3-methyl-L-tyrosine + S-adenosyl-L-methionine


name: Activation of PAKs by RAC1 and CDC42 (Homo sapiens)


name: COPI vesicle uncoating at the ER (Saccharomyces cerevisiae)


name: SENP1,2,5 proteolytically process SUMO3 (Plasmodium falciparum)


name: L-arabinitol + NADP(+) = H(+) + L-arabinose + NADPH


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Homo sapiens)


name: ADP + H(+) + N-acetyl-D-glucosamine 6-phosphate => ATP + N-acetyl-D-glucosamine


name: 3 [thioredoxin]-dithiol + arsenic triglutathione + 3 S-adenosyl-L-methionine => 3 [thioredoxin]-disulfide + 3 glutathione + 3 H(+) + 3 S-adenosyl-L-homocysteine + trimethylarsine


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Bos taurus)


name: CYP3A4 monooxygenates ATVL to 4-OH-ATVL (Canis familiaris)


name: mercaptopurine + S-adenosyl-L-methionine = 6-methylthiopurine + H(+) + S-adenosyl-L-homocysteine


name: (2S)-2-acetolactate + H(+) + NADPH => (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+)


name: (E)-5-hydroxyferulate + S-adenosyl-L-methionine => (E)-sinapate + H(+) + S-adenosyl-L-homocysteine


name: Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (Caenorhabditis elegans)


name: SERPINB13 gene expression is inhibited by RUNX1:CBFB (Homo sapiens)


name: cyclo(L-phenylalanyl-L-leucyl) + O2 <=> cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxyhexacosanoyl)-sphinganine = a 1,2-diacyl-sn-glycerol + Ins-1-P-Cer(d18:0/2-OH-26:0)


name: 6'-bromomelleolide F + FAD + 2 H2O => bromide + FADH2 + melleolide F + O2


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Rattus norvegicus)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Caenorhabditis elegans)


name: Initial activation of proMMP2 by MMP1, 7 (Xenopus tropicalis)


name: D-dopachrome + H(+) <=> 5,6-dihydroxyindole + CO2


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Danio rerio)


name: (R)-carnitine(out) + 4-(trimethylamino)butanoate(in) <=> (R)-carnitine(in) + 4-(trimethylamino)butanoate(out)


name: CDC6 association with ORC(1-6) at replication origins (Rattus norvegicus)


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2 = 18S-resolvin E2 + A + H2O


name: (S)-2-benzylsuccinyl-CoA + succinate => (S)-2-benzylsuccinate + succinyl-CoA


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate <=> 14-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5-methyluridine(54) in tRNA + ATP + hydrogen sulfide <=> 5-methyl-2-thiouridine(54) in tRNA + AMP + diphosphate


name: Lysosomal degradation of gap junction plaques (Gallus gallus)


name: PXLP-K212-CTH cleaves L-Cystathionine (Mus musculus)


name: TIRAP is phosphorylated by BTK (Homo sapiens)


name: 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 <=> H(+) + 2 H2O + 2 L-citrulline + NAD(+) + 2 nitric oxide


name: ATP binding to HSP90 triggers conformation change (Caenorhabditis elegans)


name: ATP + H(+) + NADPH + propanoate = AMP + diphosphate + NADP(+) + propanal


name: Spontaneous hydrolysis of C3 thioester (Gallus gallus)


name: telomerase RNA reverse transcriptase activity


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Homo sapiens)


name: 4,5beta-dihydrocortisone + NADP(+) <=> cortisone + H(+) + NADPH


name: Internalization of receptor bound antigen into clathrin coted vesicles (Bos taurus)


name: (R)-5-diphosphomevalonate + ADP => (R)-5-phosphomevalonate + ATP


name: PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser (Sus scrofa)


name: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO2


name: a (2E)-enoyl-CoA + FADH2 => a 2,3-saturated acyl-CoA + FAD + H(+)


name: PRKN binds p-S-Ub:MOM proteins (Rattus norvegicus)


name: 2 H(+)(in) + L-aspartyl-glycine(in) => 2 H(+)(out) + L-aspartyl-glycine(out)


name: 2 (3,4-dimethoxyphenyl)methanol + H2O2 = 2 (3,4-dimethoxyphenyl)methanol radical + 2 H2O


name: Phosphorylation of CI by SGG (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphate => a 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA


name: p-3Y-SHC1 dissociates from IGF1R (Homo sapiens)


name: 14-3-3 zeta binding allows recruitment of PI3K (Mus musculus)


name: Processing of SCF isoform 1 (Danio rerio)


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Caenorhabditis elegans)


name: NADP(+) + nicotinate <=> nicotinamide + nicotinate-adenine dinucleotide phosphate


name: THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Dictyostelium discoideum)


name: a fatty acyl-[ACP] + L-lysyl-[protein] = H(+) + holo-[ACP] + N(6)-(fatty acyl)-L-lysyl-[protein]


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Caenorhabditis elegans)


name: PHF20 binds TP53 dimethylated on K370 and K382 (Homo sapiens)


name: (R)-2-hydroxypropyl-coenzyme M + NAD(+) => 2-oxopropyl-coenzyme M + H(+) + NADH


name: Formation of dehydro-lysinonorleucine cross-links (Mus musculus)


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Bos taurus)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Xenopus tropicalis)


name: Formation of dehydro-lysinonorleucine cross-links (Rattus norvegicus)


name: Activated PTK6 binds STAP2 (Mus musculus)


name: bicyclogermacrene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 6-deoxycathasterone + O2 + reduced [NADPH--hemoprotein reductase] => (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: TAK1 is activated within the TAK1 complex (Homo sapiens)


name: MTMR14, MTMR3 dephosphorylate PI3P (Gallus gallus)


name: p-Y-STAT3 binds p-STAT5 (Rattus norvegicus)


name: 1-tetradecanoyl-sn-glycerol 3-phosphate + H2O = 1-tetradecanoyl-sn-glycerol + phosphate


name: SUMOylation of HDAC1 with SUMO1 (Rattus norvegicus)


name: p-S MAPK6,4 phosphorylate MAPKAPK5 (Rattus norvegicus)


name: H2O + sphing-4-enine-phosphocholine = H(+) + phosphocholine + sphing-4-enine


name: glycyl-L-proline(in) + H(+)(in) => glycyl-L-proline(out) + H(+)(out)


name: Calmodulin dissociates KRAS4B from the plasma membrane (Bos taurus)


name: Unknown dehydrogenase oxidizes 4-HBz (Homo sapiens)


name: a dolichyl beta-D-glucosyl phosphate + H2O => a dolichyl phosphate + D-glucose + H(+)


name: G13 activation by TP receptor (Canis familiaris)


name: BRCA1:BARD1 heterodimer autoubiquitinates (Canis familiaris)


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Saccharomyces cerevisiae)


name: 2 AMP + 2 H(+) => H2O + P(1),P(2)-bis(5'-adenosyl) diphosphate


name: ATG12 binds ATG7 dimer (Canis familiaris)


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Rattus norvegicus)


name: Phosphorylated TAK1 leaves activated TLR receptor complex (Rattus norvegicus)


name: 2 H2O + UTP => 2 H(+) + 2 phosphate + UMP


name: a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA


name: a 5'-end diphospho-adenosine in mRNA + GTP + H(+) <=> a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + diphosphate


name: TFAP2C homodimer binds MYC and KDM5B (Drosophila melanogaster)


name: Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane (Mus musculus)


name: sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity


name: ILK interacts with beta-1 integrin (Rattus norvegicus)


name: (2E)-5-methylhexenoyl-[ACP] + H(+) + NADH <=> 5-methylhexanoyl-[ACP] + NAD(+)


name: Pink1 is cleaved on healthy mitochondria (Mus musculus)


name: RAPGEF1 activates RAP1 (Xenopus tropicalis)


name: EPH receptors autophosphorylate (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O => 1-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Rattus norvegicus)


name: (13Z)-3-oxodocosenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(13Z)-docosenoyl-CoA + NADP(+)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Bos taurus)


name: p-Y694-STAT5A, p-STAT5B dimerizes (Dictyostelium discoideum)


name: 1-O-acetylmaltose + CoA => acetyl-CoA + D-maltose


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Canis familiaris)


name: (S)-2-amino-6-oxohexanoate + H2O + NAD(+) = 2 H(+) + L-2-aminoadipate + NADH


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Canis familiaris)


name: 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: lumichrome + ribitol => H(+) + H2O + riboflavin


name: H2O + N(omega)-phospho-L-arginyl-[protein] => L-arginyl-[protein] + phosphate


name: PTK6 translocates to the nucleus (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Loading of antigen peptide onto MHC class I molecule (Homo sapiens)


name: agmatine + H2O + O2 = 4-guanidinobutanal + H2O2 + NH4(+)


name: Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Gallus gallus)


name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa (Mus musculus)


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Sus scrofa)


name: a bacteriochlorophyllide f + H2O => a 7(1),7(1)-dihydroxybacteriochlorophyllide d


name: (S)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+) => D-threonine + H2O + O2


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Sus scrofa)


name: a 5'-end 5'-phospho-ribonucleoside-RNA + H2O = a 5'-end dephospho-ribonucleoside-RNA + phosphate


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Saccharomyces cerevisiae)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Caenorhabditis elegans)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Bos taurus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Canis familiaris)


name: glycyl-L-lysine(out) + 2 H(+)(out) <=> glycyl-L-lysine(in) + 2 H(+)(in)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Xenopus tropicalis)


name: D-glucose 6-phosphate + L-lysine => H2O + N(6)-(6-phospho-D-fructosyl)-L-lysine


name: (13Z)-docosenoyl-CoA + NADP(+) => (2E,13Z)-docosadienoyl-CoA + H(+) + NADPH


name: Phosphorylated SHC1 recruits SHIP (Bos taurus)


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Homo sapiens)


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Rattus norvegicus)


name: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO2


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Homo sapiens)


name: 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Danio rerio)


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA <=> (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H2O


name: O2 + torulene => 3-methyl-2-butenal + 4'-apo-beta-carotenal


name: H(+) + N-hydroxy-L-aspartate + NADPH + O2 <=> H2O + N,N-dihydroxy-L-aspartate + NADP(+)


name: 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-seryl-[protein] + H(+) + UDP


name: a 1,3-diacyl-sn-glycerol + a monoacyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol


name: 6-hydroxytryprostatin B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin B


name: ADP + H(+) + phosphate + phosphite(in) => ATP + H2O + phosphite(out)


name: RCC1 stimulates GDP to GTP exchange on RAN (Caenorhabditis elegans)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Mus musculus)


name: Aquaporins passively transport urea into cells (Saccharomyces cerevisiae)


name: 3 O2 + protoporphyrinogen IX = 3 H2O2 + protoporphyrin IX


name: (11R)-methyl carlactonoate + 2-oxoglutarate + O2 => (11R)-hydroxymethyl carlactonoate + CO2 + succinate


name: NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Gallus gallus)


name: [sulfur carrier]-SH + L-alanine => [sulfur carrier]-H + L-cysteine


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Rattus norvegicus)


name: ULK complex translocates to the ER (Bos taurus)


name: NSF and SNAPs bind cis-SNARE complex (Danio rerio)


name: F1Fo ATP synthase dimerizes (Drosophila melanogaster)


name: Aquaporins passively transport glycerol out of cells (Schizosaccharomyces pombe)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Saccharomyces cerevisiae)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA <=> 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: N-formyl-L-kynurenine => L-tryptophan + O2


name: berberine + 2 H2O2 => (S)-canadine + H(+) + 2 O2


name: 3-oxodocosanoyl-CoA + H(+) + NADH => (3S)-hydroxydocosanoyl-CoA + NAD(+)


name: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate


name: HSD17B13 binds lipid droplets (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: AFG3L2 degrades mitochondrial inner membrane proteins (Dictyostelium discoideum)


name: XK:KEL:Zn2+ cleaves EDN3 (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(beta-D-glucuronate) => 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Drosophila melanogaster)


name: Cytosolic PLK1 translocates to the nucleus (Schizosaccharomyces pombe)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Homo sapiens)


name: CO2 + L-ornithine + NH4(+) => 2 H(+) + H2O + L-citrulline


name: TXLNA (IL14) binds syntaxin3 (Bos taurus)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Caenorhabditis elegans)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)


name: S-adenosyl-L-methionine transmembrane transporter activity


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Homo sapiens)


name: acetoin + CoA + NAD(+) <=> acetaldehyde + acetyl-CoA + H(+) + NADH


name: TP53 stimulates STEAP3 expression (Homo sapiens)


name: (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + hexanoyl-CoA + oxidized [electron-transfer flavoprotein]


name: 2,5-didehydro-D-gluconate + H(+) + NADH <=> 5-dehydro-D-gluconate + NAD(+)


name: 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + NADH => 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + NAD(+)


name: an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + 3 S-adenosyl-L-methionine => an N,N,N-trimethylornithine lipid + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Sus scrofa)


name: STING recruits TBK1 and STAT6 (Drosophila melanogaster)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Saccharomyces cerevisiae)


name: 2,3-dihydroxybenzoate + H2O + NAD(+) => H(+) + NADH + O2 + salicylate


name: Loading of dopamine into synaptic veiscles (Sus scrofa)


name: PAK1-3 phosphorylates VE-cadherin (Xenopus tropicalis)


name: 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate => 7,8-dihydroneopterin 3'-triphosphate + H2O


name: an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,8Z,11Z,14Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Rattus norvegicus)


name: a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine <=> a lipid A disaccharide + H(+) + UDP


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 19-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-prenylphlorisobutanophenone + dimethylallyl diphosphate => deoxycohumulone + diphosphate


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Xenopus tropicalis)


name: Activation of ATP sensitive Potassium channels in muscle cells (Rattus norvegicus)


name: STARD7 binds PC (Drosophila melanogaster)


name: (25S)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: prephenate + S-adenosyl-L-methionine => 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O


name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Canis familiaris)


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Drosophila melanogaster)


name: 2-oxoglutarate + a methylated nucleobase within DNA + O2 <=> a nucleobase within DNA + CO2 + formaldehyde + succinate


name: CLPXP binds mitochondrial matrix proteins (Drosophila melanogaster)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Mus musculus)


name: H2O + UDP-alpha-D-glucose => alpha-D-glucose 1-phosphate + 2 H(+) + UMP


name: [thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite <=> 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol


name: dehydrogriseofulvin + H(+) + NADPH <=> griseofulvin + NADP(+)


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Danio rerio)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Rattus norvegicus)


name: dCDP(in) + UTP(out) => dCDP(out) + UTP(in)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-alanine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-alanine


name: ATP + glutathione(in) + glycochenodeoxycholate(in) + H2O <=> ADP + glutathione(out) + glycochenodeoxycholate(out) + H(+) + phosphate


name: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine


name: The Ligand:GPCR:G12/13 complex dissociates (Homo sapiens)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Danio rerio)


name: a very-long-chain (3R)-3-hydroxyacyl-CoA + NAD(+) => a very-long-chain 3-oxoacyl-CoA + H(+) + NADH


name: Egress of internalized antigen into cytosol from early endosome (Homo sapiens)


name: Endocytosis and degradation of apoA-I (Homo sapiens)


name: an acyl-CoA + sn-glycero-3-phosphoethanolamine = a monoacyl-sn-glycero-3-phosphoethanolamine + CoA


name: Exocytosis of specific granule lumen proteins (Schizosaccharomyces pombe)


name: inositol heptakisphosphate 5-kinase activity


name: Binding of SHC1 to insulin receptor (Canis familiaris)


name: YOD1 binds VCP (Drosophila melanogaster)


name: (4R)-hydroxy-(6R)-2,2,6-trimethylcyclohexanone + NAD(+) <=> (6R)-2,2,6-trimethyl-1,4-cyclohexanedione + H(+) + NADH


name: Properdin stabilizes C3b:Bb bound to cell surfaces (Homo sapiens)


name: Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Rattus norvegicus)


name: glycerol-3-phosphate dehydrogenase (NAD+) activity


name: (9Z,12Z)-octadecadienoate + O2 => (2R,9Z,12Z)-2-hydroperoxyoctadecadienoate


name: STING binds c-di-GMP (Xenopus tropicalis)


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O => 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: DT:HBEGF:CD9 is transported from clathrin-coated vesicle to endosome (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate => (-)-delta-cadinene + diphosphate


name: SYK autophosphorylates at the activated BCR (Rattus norvegicus)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Xenopus tropicalis)


name: PGLYRP3,4 binds bacterial peptidoglycan (Drosophila melanogaster)


name: PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL4 complex (Mus musculus)


name: (8S)-annullatin E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-hydroxymethyl-3-pentylphenol + O2 + reduced [NADPH--hemoprotein reductase]


name: a neolactoside IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + H(+) + UDP


name: p-4Y-SIRPA:CD47 binds GRB2-1 (Sus scrofa)


name: PPARA binds RXRA (Caenorhabditis elegans)


name: ESR binds STRN (Drosophila melanogaster)


name: AH2 + GTP + S-adenosyl-L-methionine <=> 3'-deoxy-3',4'-didehydro-GTP + 5'-deoxyadenosine + A + H(+) + H2O + L-methionine


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-ribose 1-phosphate = (2R)-3-phosphoglycerate + alpha-D-ribose 1,5-bisphosphate + H(+)


name: (2E)-dodecenedioyl-CoA + H2O2 => dodecanedioyl-CoA + O2


name: Phosphorylation of PKC theta (Bos taurus)


name: (3S)-hydroxytetradecanedioyl-CoA + NAD(+) = 3-oxotetradecanedioyl-CoA + H(+) + NADH


name: USP8 deubiquitinates STAM2:HGS (Canis familiaris)


name: H(+)(in) + K(+)(in) + Na(+)(out) + serotonin(out) => H(+)(out) + K(+)(out) + Na(+)(in) + serotonin(in)


name: 1-O-(trans-sinapoyl)-beta-D-glucose + anthocyanin A8 <=> anthocyanin A11 + D-glucose


name: (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase]


name: ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE (Sus scrofa)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)


name: 3-oxopropanoate + CoA + NAD(+) <=> acetyl-CoA + CO2 + NADH


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Danio rerio)


name: ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Homo sapiens)


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Danio rerio)


name: 2 H(+) + methylmalonate + NADH => (S)-2-methyl-3-oxopropanoate + H2O + NAD(+)


name: XPO1 binds p-S69,73 MITF-M (Mus musculus)


name: 3'-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] <=> 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: Acireductone is oxidized to MOB (Canis familiaris)


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Rattus norvegicus)


name: F2R binds ARRB2 (Caenorhabditis elegans)


name: PAK1,2,3 phosphorylates MAPK6,4 (Danio rerio)


name: Cypridina luciferin + O2 = CO2 + hnu + oxidized Cypridina luciferin


name: methyl aklanonate + S-adenosyl-L-homocysteine => aklanonate + S-adenosyl-L-methionine


name: a quinol + dihydroxyacetone phosphate => a quinone + sn-glycerol 3-phosphate


name: L-tyrosine + phosphate => 4-O-phospho-L-tyrosine + H2O


name: (3R)-3-[(carboxymethyl)amino]butanoate + H(+) + holo-[ACP] = (2E)-butenoyl-[ACP] + glycine + H2O


name: NIPAs transport Mg2+ from extracellular region to cytosol (Sus scrofa)


name: CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 (Homo sapiens)


name: Phosphorylation of ZAP-70 by Lck (Mus musculus)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Saccharomyces cerevisiae)


name: N-WASP binds ARP2/3 and G-actin (Rattus norvegicus)


name: Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Xenopus tropicalis)


name: EPH:EFN dimers tetramerise (Xenopus tropicalis)


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Xenopus tropicalis)


name: CBL-mediated ubiquitination of CIN85 (Sus scrofa)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Sus scrofa)


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) (Gallus gallus)


name: beta-alanine(in) + H(+)(in) = beta-alanine(out) + H(+)(out)


name: a secondary aliphatic amine + H2O + O2 = a primary amine + an aldehyde + H2O2


name: (2E)-octenoyl-CoA + H2O => 3-hydroxyoctanoyl-CoA


name: DUX4, TPRXL, TPRX1, and TPRX2 bind the DUXB gene (Homo sapiens)


name: DELE1(143-515) binds EIF2AK1 (HRI) (Sus scrofa)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Dictyostelium discoideum)


name: PCSK9 binds PCSK9 inhibitors (Homo sapiens)


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Mus musculus)


name: 2 4-hydroxyphenylacetate + 2 CO2 => 2 3-(4-hydroxyphenyl)pyruvate + O2


name: 5beta-cholestan-3alpha,7alpha,27-triol is translocated from the cytosol to the mitochondrial matrix (Homo sapiens)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Bos taurus)


name: 2 methanethiol + NAD(+) => dimethyl disulfide + H(+) + NADH


name: Proteasomal clevage of exogenous antigen (Mus musculus)


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)


name: (+)-isomalbrancheamide B + chloride + FAD + 2 H(+) = (+)-malbrancheamide + FADH2


name: MECP2 binds the PTPN4 gene promoter (Homo sapiens)


name: atROL binds to RBP2 (Xenopus tropicalis)


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Caenorhabditis elegans)


name: 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+) => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O


name: GDP-beta-L-fucose + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate <=> GDP + H(+) + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: H(+)(out) + rifampicin(in) <=> H(+)(in) + rifampicin(out)


name: Fatty acid ligands activate PPARA (Danio rerio)


name: ATAT acetylates microtubules (Rattus norvegicus)


name: H(+) + malonyl-CoA + S-anthraniloyl-L-cysteinyl-[PqsD protein] <=> (2-aminobenzoyl)acetyl-CoA + CO2 + L-cysteinyl-[PqsD protein]


name: Association of Emi1 with Cdh1 (Rattus norvegicus)


name: JAK2 phosphorylation of GHR (Mus musculus)


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Mus musculus)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Gallus gallus)


name: Binding of ADAR2 homodimer to dsRNA duplex (Rattus norvegicus)


name: 3 H(+) + holo-[2-methylbutanoate polyketide synthase] + 2 malonyl-CoA + 2 NADPH + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CO2 + 2 CoA + H2O + 2 NADP(+) + S-adenosyl-L-homocysteine


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Homo sapiens)


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(out) + ADP + H(+) + phosphate => 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(in) + ATP + H2O


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Caenorhabditis elegans)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Canis familiaris)


name: PDE3B hydrolyses cAMP to AMP (Bos taurus)


name: ATPase synthesizes ATP (Caenorhabditis elegans)


name: RHOG GAPs stimulate RHOG GTPase activity (Mus musculus)


name: SLC36A4 transports extracellular L-Pro to the cytosol (Rattus norvegicus)


name: chloride(out) + L-isoleucine(out) + 2 Na(+)(out) <=> chloride(in) + L-isoleucine(in) + 2 Na(+)(in)


name: H2O2 + NH4(+) + pyridoxal => H2O + O2 + pyridoxamine


name: Trans-homodimerization of Neurofascin (Sus scrofa)


name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Sus scrofa)


name: H2O + phosphoethanolamine <=> acetaldehyde + NH4(+) + phosphate


name: 2-[(1R,8S,14R,15R)-11-hydroxy-14,15-bis[(6E)-oct-6-en-1-yl]-3,5,9-trioxo-4,10-dioxatetracyclo[9.4.0.0(2,6).0(8,12)]pentadeca-2(6),12-dien-8-yl]acetate + 3 2-oxoglutarate + 3 O2 <=> 3 CO2 + H2O + phomoidride A + 3 succinate


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Sus scrofa)