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The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000697", "l": "negative regulation of epithelial cell differentiation involved in kidney development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021989", "l": "olfactory cortex development", "d": ["The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. 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The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903082", "l": "positive regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "50.380901826805861", "identifiers": [{"i": "GO:0051932", "l": "synaptic transmission, GABAergic", "d": ["The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. 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This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021893", "l": "cerebral cortex GABAergic interneuron fate commitment", "d": ["The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900044", "l": "regulation of protein K63-linked ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090170", "l": "regulation of Golgi inheritance", "d": ["Any process that modulates the rate, frequency or extent of Golgi inheritance. 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Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903866", "l": "palisade mesophyll development", "d": ["The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0035794", "l": "positive regulation of mitochondrial membrane permeability", "d": ["Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014916", "l": "regulation of lung blood pressure", "d": ["The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021996", "l": "lamina terminalis formation", "d": ["The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902660", "l": "negative regulation of glucose mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990216", "l": "symbiont-mediated activation of of host transcription", "d": ["A process in which a symbiont initiates, promotes, or enhances transcription of genes into mRNA in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110034", "l": "negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045706", "l": "positive regulation of salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0042539", "l": "hypotonic salinity response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0051155", "l": "positive regulation of striated muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.245794426288597", "identifiers": [{"i": "GO:0002791", "l": "regulation of peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of peptide secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140329", "l": "lysophospholipid translocation", "d": ["The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905275", "l": "Rohon-Beard neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097703", "l": "cellular response to pulsatile fluid shear stress", "d": ["Any response to pulsatile fluid shear stress that occurs at the level of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0002007", "l": "detection of hypoxic conditions in blood by chemoreceptor signaling", "d": ["The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0035196", "l": "miRNA processing", "d": ["A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031860", "l": "telomeric 3' overhang formation", "d": ["The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0070295", "l": "renal water absorption", "d": ["A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.492767218801774", "identifiers": [{"i": "GO:0071168", "l": "protein localization to chromatin", "d": ["Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061698", "l": "protein deglutarylation", "d": ["The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905305", "l": "negative regulation of cardiac myofibril assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001127", "l": "methane biosynthetic process from formic acid", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a formic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905336", "l": "negative regulation of aggrephagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061192", "l": "negative regulation of vacuole fusion, non-autophagic", "d": ["Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043454", "l": "alkyne catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0060119", "l": "inner ear receptor cell development", "d": ["The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900625", "l": "positive regulation of monocyte aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061444", "l": "endocardial cushion cell development", "d": ["The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031107", "l": "septin ring disassembly", "d": ["The controlled breakdown of a septin ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905453", "l": "regulation of myeloid progenitor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035016", "l": "elongation of arista lateral", "d": ["The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016475", "l": "detection of nuclear:cytoplasmic ratio", "d": ["The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901907", "l": "diadenosine pentaphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090076", "l": "relaxation of skeletal muscle", "d": ["A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080159", "l": "zygote elongation", "d": ["The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009650", "l": "UV protection", "d": ["Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000441", "l": "negative regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070651", "l": "nonfunctional rRNA decay", "d": ["An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.868301077661471", "identifiers": [{"i": "GO:0045893", "l": "positive regulation of DNA-templated transcription", "d": ["Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060752", "l": "intestinal phytosterol absorption", "d": ["Any process in which phytosterols are taken up from the contents of the intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0006152", "l": "purine nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048205", "l": "COPI coating of Golgi vesicle", "d": ["The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035155", "l": "negative regulation of terminal cell fate specification, open tracheal system", "d": ["Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060474", "l": "positive regulation of flagellated sperm motility involved in capacitation", "d": ["The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042859", "l": "chrysobactin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045626", "l": "negative regulation of T-helper 1 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002797", "l": "regulation of antibacterial peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044398", "l": "envenomation resulting in induction of edema in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072247", "l": "metanephric glomerular parietal epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900316", "l": "negative regulation of maltopentaose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140882", "l": "zinc export across plasma membrane", "d": ["The directed movement of zinc ions from a cell, into the extracellular region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0033627", "l": "cell adhesion mediated by integrin", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021678", "l": "third ventricle development", "d": ["The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. 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A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006307", "l": "DNA dealkylation involved in DNA repair", "d": ["The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:2000926", "l": "positive regulation of cellodextrin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905640", "l": "response to acetaldehyde", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010727", "l": "negative regulation of hydrogen peroxide metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032739", "l": "positive regulation of interleukin-16 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-16 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048093", "l": "positive regulation of male pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048441", "l": "petal development", "d": ["The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0098711", "l": "iron ion import across plasma membrane", "d": ["The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034181", "l": "positive regulation of toll-like receptor 13 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0120110", "l": "interphase mitotic telomere clustering", "d": ["The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0005988", "l": "lactose metabolic process", "d": ["The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0001991", "l": "regulation of systemic arterial blood pressure by circulatory renin-angiotensin", "d": ["The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0075187", "l": "hyphopodium formation", "d": ["The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0007308", "l": "oocyte construction", "d": ["The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. 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These may include chemical modification or transport of sulfide away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010250", "l": "S-methylmethionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0002467", "l": "germinal center formation", "d": ["The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0042368", "l": "vitamin D biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021715", "l": "inferior olivary nucleus formation", "d": ["The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900487", "l": "regulation of [2Fe-2S] cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0170041", "l": "non-proteinogenic amino acid metabolic process", "d": ["The chemical reactions and pathways involving non-proteingenic amino acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019542", "l": "propionate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1905651", "l": "regulation of artery morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of artery morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0002452", "l": "B cell receptor editing", "d": ["The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0055113", "l": "epiboly involved in gastrulation with mouth forming second", "d": ["The expansion of one cell sheet over other cells involved in deuterostomic gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039525", "l": "modulation by virus of host chromatin organization", "d": ["Any process in which a virus effects a change in the organization of chromatin in the host."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002103", "l": "endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0097494", "l": "regulation of vesicle size", "d": ["Any process that modulates the size of a vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0046643", "l": "regulation of gamma-delta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070150", "l": "mitochondrial glycyl-tRNA aminoacylation", "d": ["The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045728", "l": "respiratory burst after phagocytosis", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900570", "l": "diorcinol metabolic process", "d": ["The chemical reactions and pathways involving diorcinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000332", "l": "regulation of blood microparticle formation", "d": ["Any process that modulates the frequency, rate or extent of blood microparticle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035119", "l": "embryonic pelvic fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070582", "l": "theta DNA replication", "d": ["A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0003091", "l": "renal water homeostasis", "d": ["Renal process involved in the maintenance of an internal steady state of water in the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0046940", "l": "nucleoside monophosphate phosphorylation", "d": ["The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090096", "l": "positive regulation of metanephric cap mesenchymal cell proliferation", "d": ["Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038015", "l": "positive regulation of insulin receptor signaling pathway by insulin receptor internalization", "d": ["Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990522", "l": "tail spike morphogenesis", "d": ["The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061196", "l": "fungiform papilla development", "d": ["The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000470", "l": "positive regulation of peroxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of peroxidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905363", "l": "positive regulation of endosomal vesicle fusion", "d": ["Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080187", "l": "floral organ senescence", "d": ["The last stage of flower development during which programmed degradation of macromolecules and nutrient recycling take place."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0090670", "l": "RNA localization to Cajal body", "d": ["A process in which an RNA is transported to, or maintained in, a Cajal body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010139", "l": "pyrimidine deoxyribonucleotide salvage", "d": ["The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.653457143972261", "identifiers": [{"i": "GO:0061004", "l": "pattern specification involved in kidney development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001757", "l": "somite specification", "d": ["The process in which individual somites establish identity during embryogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000463", "l": "positive regulation of excitatory postsynaptic potential", "d": ["Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003116", "l": "regulation of vasoconstriction by norepinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905238", "l": "cellular response to cyclosporin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048833", "l": "specification of floral organ number", "d": ["Any process that modulates the number of floral organs formed in a floral whorl."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.375074843138819", "identifiers": [{"i": "GO:0031401", "l": "positive regulation of protein modification process", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007509", "l": "mesoderm migration involved in gastrulation", "d": ["The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072281", "l": "mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.800431741157325", "identifiers": [{"i": "GO:0050432", "l": "catecholamine secretion", "d": ["The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0045332", "l": "phospholipid translocation", "d": ["The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141014", "l": "ribosome hibernation", "d": ["A cellular process that results in the silencing of ribosomes in quiescent cells. Quiescence takes place when cells encounter unfavorable conditions and cease to grow in bacteria and yeast. It also takes place in some specialized cells in higher eukaryotes, such as eggs. Ribosomes in a hibernation state are kept silent via association with proteins with inhibitory and protective functions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001182", "l": "RNA polymerase I promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002284", "l": "myeloid dendritic cell differentiation involved in immune response", "d": ["The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060794", "l": "leaflet morphogenesis", "d": ["The process in which the anatomical structures of the leaflet are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902738", "l": "regulation of chondrocyte differentiation involved in endochondral bone morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002403", "l": "T cell tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071854", "l": "cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly", "d": ["The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0035561", "l": "regulation of chromatin binding", "d": ["Any process that modulates the frequency, rate or extent of chromatin binding. 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Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905304", "l": "regulation of cardiac myofibril assembly", "d": ["Any process that modulates the frequency, rate or extent of cardiac myofibril assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0034331", "l": "cell junction maintenance", "d": ["The organization process that preserves a cell junction in a stable functional or structural state. 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The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072305", "l": "negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0033083", "l": "regulation of immature T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of immature T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902913", "l": "positive regulation of neuroepithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0043396", "l": "corticotropin-releasing hormone secretion", "d": ["The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1903051", "l": "negative regulation of proteolysis involved in protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0160062", "l": "cutin-based cuticle development", "d": ["The process whose specific outcome is the progression of the cutin-based cuticle over time, from its formation to the mature structure. 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The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002877", "l": "regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990390", "l": "protein K33-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120184", "l": "negative regulation of focal adhesion disassembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071296", "l": "cellular response to biotin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901729", "l": "monensin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monensin A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060836", "l": "lymphatic endothelial cell differentiation", "d": ["The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019379", "l": "sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)", "d": ["The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019516", "l": "lactate oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006884", "l": "cell volume homeostasis", "d": ["Any process involved in maintaining the steady state of a cell's volume. 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"identifiers": [{"i": "GO:0031457", "l": "glycine betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905796", "l": "regulation of intraciliary anterograde transport", "d": ["Any process that modulates the frequency, rate or extent of intraciliary anterograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072082", "l": "specification of proximal tubule identity", "d": ["The process in which the proximal tubule of the kidney nephron acquires its identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031654", "l": "regulation of heat dissipation", "d": ["Any process that modulates the rate or extent of heat dissipation."], "t": 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This is one mechanism to prevent polytuby, the simultaneous penetration of ovules by multiple pollen tubes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904907", "l": "regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0031279", "l": "regulation of cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048683", "l": "regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051467", "l": "detection of steroid hormone stimulus", "d": ["The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010913", "l": "regulation of sterigmatocystin biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903444", "l": "negative regulation of brown fat cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071268", "l": "homocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060211", "l": "regulation of nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0043144", "l": "sno(s)RNA processing", "d": ["Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902919", "l": "poly(5-hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021981", "l": "subpallium radially oriented migration", "d": ["The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002395", "l": "immune response in nasopharyngeal-associated lymphoid tissue", "d": ["An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010375", "l": "stomatal complex patterning", "d": ["The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0090558", "l": "plant epidermis development", "d": ["The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0061212", "l": "mesonephric juxtaglomerular apparatus development", "d": ["The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001191", "l": "regulation of gamma-delta T cell activation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905695", "l": "positive regulation of phosphatidic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0032954", "l": "regulation of cytokinetic process", "d": ["Any process that modulates the frequency, rate or extent of a cytokinetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904156", "l": "DN3 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006404", "l": "RNA import into nucleus", "d": ["The import of RNA from the cytoplasm to the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010166", "l": "wax metabolic process", "d": ["The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900419", "l": "regulation of cellular alcohol catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019616", "l": "catechol catabolic process, meta-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903301", "l": "positive regulation of hexokinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of hexokinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045632", "l": "negative regulation of mechanoreceptor differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045107", "l": "intermediate filament polymerization", "d": ["Assembly of intermediate filaments by the addition of component monomers to a filament. 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Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106150", "l": "zearalenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001311", "l": "lysobisphosphatidic acid metabolic process", "d": ["The chemical reactions and pathways involving a lysobisphosphatidic acid. 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Upon specification, the cell fate can be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0006942", "l": "regulation of striated muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of striated muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0061528", "l": "aspartate secretion", "d": ["The regulated release of aspartate by a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1905292", "l": "regulation of neural crest cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of neural crest cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904237", "l": "positive regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003186", "l": "tricuspid valve morphogenesis", "d": ["The process in which the structure of the tricuspid valve is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061364", "l": "apoptotic process involved in luteolysis", "d": ["The apoptotic process that contributes to luteolysis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904871", "l": "positive regulation of protein localization to Cajal body", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032949", "l": "regulation of alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070759", "l": "negative regulation of interleukin-35-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0018230", "l": "peptidyl-L-cysteine S-palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061939", "l": "c-di-GMP signaling", "d": ["Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060237", "l": "regulation of fungal-type cell wall organization", "d": ["Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0140499", "l": "negative regulation of mitotic spindle assembly checkpoint signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905168", "l": "positive regulation of double-strand break repair via homologous recombination", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.779658003941762", "identifiers": [{"i": "GO:0010646", "l": "regulation of cell communication", "d": ["Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106247", "l": "negative regulation of poly(A)-specific ribonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032751", "l": "positive regulation of interleukin-27 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-27 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000540", "l": "negative regulation of protein geranylgeranylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048459", "l": "floral whorl structural organization", "d": ["The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071493", "l": "cellular response to UV-B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009836", "l": "fruit ripening, climacteric", "d": ["A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0042758", "l": "long-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0001774", "l": "microglial cell activation", "d": ["The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032227", "l": "negative regulation of synaptic transmission, dopaminergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070054", "l": "mRNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009151", "l": "purine deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0002063", "l": "chondrocyte development", "d": ["The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002331", "l": "pre-B cell allelic exclusion", "d": ["Expression of a single heavy chain allele during pre-B cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006398", "l": "mRNA 3'-end processing by stem-loop binding and cleavage", "d": ["Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060279", "l": "positive regulation of ovulation", "d": ["Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0093002", "l": "response to nematicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0015986", "l": "proton motive force-driven ATP synthesis", "d": ["The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000716", "l": "transcription-coupled nucleotide-excision repair, DNA damage recognition", "d": ["The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904053", "l": "positive regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0055064", "l": "chloride ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062120", "l": "LinE complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009127", "l": "purine nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140147", "l": "zinc ion export from vacuole", "d": ["The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046464", "l": "acylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006756", "l": "AMP phosphorylation", "d": ["The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. 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"95.425240171993906", "identifiers": [{"i": "GO:1903489", "l": "positive regulation of lactation", "d": ["Any process that activates or increases the frequency, rate or extent of lactation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090650", "l": "cellular response to oxygen-glucose deprivation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106342", "l": "omega-hydroxyceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046095", "l": "deoxyinosine biosynthetic 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"biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051105", "l": "regulation of DNA ligation", "d": ["Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0099550", "l": "trans-synaptic signaling, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0034377", "l": "plasma lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0060029", "l": "convergent extension involved in organogenesis", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0072689", "l": "MCM complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900359", "l": "positive regulation of nigerotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of nigerotriose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": 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"identifiers": [{"i": "GO:0140425", "l": "galactose import across plasma membrane", "d": ["The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902830", "l": "negative regulation of spinal cord association neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0062173", "l": "brexanolone metabolic process", "d": ["The chemical reactions and pathways by which living organisms transform brexanolone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032194", "l": "ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate", "d": ["The chemical 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of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000414", "l": "negative regulation of fibronectin-dependent thymocyte migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052710", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900561", "l": "dehydroaustinol metabolic process", "d": ["The chemical 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antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032785", "l": "negative regulation of DNA-templated transcription, elongation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018190", "l": "protein octanoylation", "d": ["The modification of a protein amino acid by formation of an ester or amide with octanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0044576", "l": "pentose catabolic process to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000782", "l": "regulation of establishment of cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.723777338832122", "identifiers": [{"i": "GO:0001823", "l": "mesonephros development", "d": ["The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0007405", "l": "neuroblast proliferation", "d": ["The expansion of a neuroblast population by cell division. 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Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0009086", "l": "methionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000885", "l": "galactoglucomannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010933", "l": "positive regulation of macrophage tolerance induction", "d": ["Any process that increases the frequency, rate, or extent of B cell tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021592", "l": "fourth ventricle development", "d": ["The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0051222", "l": "positive regulation of protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0051322", "l": "anaphase", "d": ["The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042850", "l": "L-sorbose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0043942", "l": "negative regulation of sexual sporulation resulting in formation of a cellular spore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019612", "l": "4-toluenecarboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035116", "l": "embryonic hindlimb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039677", "l": "exit of virus from host cell nucleus via nuclear envelope disassembly", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1903299", "l": "regulation of hexokinase activity", "d": ["Any process that modulates the frequency, rate or extent of hexokinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0022904", "l": "respiratory electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048527", "l": "lateral root development", "d": ["The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. 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The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901386", "l": "negative regulation of voltage-gated calcium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021619", "l": "hypoglossal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904704", "l": "positive regulation of protein localization to adherens junction", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048445", "l": "carpel morphogenesis", "d": ["The process in which the anatomical structures of the carpel are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0002838", "l": "negative regulation of immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.151811589581797", "identifiers": [{"i": "GO:0003002", "l": "regionalization", "d": ["The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097178", "l": "ruffle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0042814", "l": "monopolar cell growth", "d": ["Polarized growth from one end of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061907", "l": "negative regulation of AMPA receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034168", "l": "negative regulation of toll-like receptor 10 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046223", "l": "aflatoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046193", "l": "anaerobic phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000241", "l": "diakinesis", "d": ["The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034371", "l": "chylomicron remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty 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of purine metabolism in certain mammals and the main excretory product in uricotelic animals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901081", "l": "negative regulation of relaxation of smooth muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001089", "l": "maltotriose transport", "d": ["The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0016144", "l": "S-glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been 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It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003359", "l": "noradrenergic neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903617", "l": "positive regulation of mitotic cytokinesis, division site positioning", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, division site positioning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061282", "l": "specification of mesonephric nephron tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044873", "l": "lipoprotein localization to membrane", "d": ["A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903139", "l": "positive regulation of cell wall integrity MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000694", "l": "regulation of phragmoplast microtubule organization", "d": ["Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904828", "l": "positive regulation of hydrogen sulfide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000921", "l": "regulation of arabinoxylan-containing compound catabolic process", "d": ["Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904278", "l": "positive regulation of wax biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of wax biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900822", "l": "regulation of ergot alkaloid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036511", "l": "trimming of first mannose on A branch", "d": ["The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044592", "l": "response to pullulan", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001814", "l": "negative regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061360", "l": "optic chiasma development", "d": ["The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. 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Neural rod formation occurs during primary neurulation in teleosts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060861", "l": "positive regulation of floral organ abscission", "d": ["Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070372", "l": "regulation of ERK1 and ERK2 cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045496", "l": "male analia development", "d": ["The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0008038", "l": "neuron recognition", "d": ["The process in which a neuronal cell in a multicellular organism interprets its surroundings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902605", "l": "heterotrimeric G-protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0071625", "l": "vocalization behavior", "d": ["The behavior in which an organism produces sounds by a mechanism involving its respiratory system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035263", "l": "genital disc sexually dimorphic development", "d": ["The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. 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Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019458", "l": "methionine catabolic process via 2-oxobutanoate", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001214", "l": "positive regulation of vasculogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of vasculogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070197", "l": "meiotic attachment of telomere to nuclear envelope", "d": ["The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000852", "l": "regulation of corticosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of corticosterone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070239", "l": "regulation of activated T cell autonomous cell death", "d": ["Any process that modulates the occurrence or rate of activated T cell autonomous cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0046543", "l": "development of secondary female sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. 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For example, cell communication occurs among more than one cell, but occurs at the cellular level."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.593242189043409", "identifiers": [{"i": "GO:0018205", "l": "peptidyl-lysine modification", "d": ["The modification of peptidyl-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001051", "l": "positive regulation of tendon cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of tendon cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0043248", "l": "proteasome assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active proteasome complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0009082", "l": "branched-chain amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046236", "l": "mandelate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. 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Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0014743", "l": "regulation of muscle hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of muscle hypertrophy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032757", "l": "positive regulation of interleukin-8 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-8 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901395", "l": "regulation of transforming growth factor beta2 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0075118", "l": "symbiont-mediated perturbation of host G protein-coupled receptor signal transduction pathway", "d": ["A process by which a symbiont alters or subverts the normal execution of a host G protein-coupled receptor signal transduction pathway. 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This is a neurological process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002613", "l": "regulation of monocyte antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061211", "l": "mesonephric collecting duct development", "d": ["The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022027", "l": "interkinetic nuclear migration", "d": ["The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045228", "l": "slime layer polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0016093", "l": "polyprenol metabolic process", "d": ["The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903687", "l": "negative regulation of border follicle cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045797", "l": "positive regulation of intestinal cholesterol absorption", "d": ["Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0097355", "l": "protein localization to heterochromatin", "d": ["Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.528207968973732", "identifiers": [{"i": "GO:0031669", "l": "cellular response to nutrient levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039564", "l": "symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT2 activity", "d": ["A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1990183", "l": "lymphatic vascular process in circulatory system", "d": ["A circulatory process that occurs at the level of the lymphatic vasculature."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0080053", "l": "response to phenylalanine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071242", "l": "cellular response to ammonium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071409", "l": "cellular response to cycloheximide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900692", "l": "regulation of (+)-kotanin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.161717068681156", "identifiers": [{"i": "GO:0022408", "l": "negative regulation of cell-cell adhesion", "d": ["Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010058", "l": "regulation of atrichoblast fate specification", "d": ["Any process that modulates atrichoblast fate specification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001301", "l": "lipoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a lipoxin. 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The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900276", "l": "regulation of proteinase activated receptor activity", "d": ["Any process that modulates the frequency, rate or extent of proteinase activated receptor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075228", "l": "positive regulation of encysted zoospore germination", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048100", "l": "wing disc anterior/posterior pattern formation", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900102", "l": "negative regulation of endoplasmic reticulum unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033599", "l": "regulation of mammary gland epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0045761", "l": "regulation of adenylate cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072230", "l": "metanephric proximal straight tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. 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A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904397", "l": "negative regulation of neuromuscular junction development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046358", "l": "butyrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0039663", "l": "membrane fusion involved in viral entry into host cell", "d": ["Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904138", "l": "positive regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007464", "l": "R3/R4 cell fate commitment", "d": ["The process in which the R3/R4 photoreceptors commit to their cell fate. 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Menaquinones have vitamin K activity and are known as vitamin K2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0061119", "l": "regulation of positive chemotaxis to cAMP by chlorinated alkylphenone", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060867", "l": "fruit abscission", "d": ["The controlled shedding of a fruit."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035349", "l": "coenzyme A transmembrane transport", "d": ["The process in which coenzyme A is transported across a membrane. 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Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032911", "l": "negative regulation of transforming growth factor beta1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061309", "l": "cardiac neural crest cell development involved in outflow tract morphogenesis", "d": ["The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060767", "l": "epithelial cell proliferation involved in prostate gland development", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0042212", "l": "cresol metabolic process", "d": ["The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:1903318", "l": "negative regulation of protein maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070586", "l": "cell-cell adhesion involved in gastrulation", "d": ["The attachment of one cell to another cell affecting gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0030245", "l": "cellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021632", "l": "optic nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010080", "l": "regulation of floral meristem growth", "d": ["Any process involved in maintaining the size and shape of a floral meristem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0039671", "l": "evasion by virus of host natural killer cell activity", "d": ["Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046826", "l": "negative regulation of protein export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048548", "l": "regulation of pinocytosis", "d": ["Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0071613", "l": "granzyme B production", "d": ["The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000800", "l": "regulation of endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010910", "l": "positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity", "d": ["Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010778", "l": "meiotic DNA repair synthesis involved in reciprocal meiotic recombination", "d": ["The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046356", "l": "acetyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1905343", "l": "regulation of cohesin unloading", "d": ["Any process that modulates the frequency, rate or extent of cohesin unloading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900054", "l": "positive regulation of retinoic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "17.297111969422783", "identifiers": [{"i": "GO:0019538", "l": "protein metabolic process", "d": ["The chemical reactions and pathways involving a protein. 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"GO:0006360", "l": "transcription by RNA polymerase I", "d": ["The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903810", "l": "L-histidine import across plasma membrane", "d": ["The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000476", "l": "positive regulation of opioid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019415", "l": "acetate biosynthetic process from carbon monoxide", "d": ["The chemical reactions and pathways resulting in 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"biolink:BiologicalProcess", "ic": "56.687978462072721", "identifiers": [{"i": "GO:0034654", "l": "nucleobase-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900497", "l": "regulation of butyryl-CoA catabolic process to butanol", "d": ["Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0060563", "l": "neuroepithelial cell differentiation", "d": ["The process in which epiblast cells acquire specialized features of neuroepithelial cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0052170", "l": "symbiont-mediated suppression of host innate immune response", "d": ["A process in which a symbiont inhibits or disrupts the normal execution of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0010634", "l": "positive regulation of epithelial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0035510", "l": "DNA dealkylation", "d": ["The removal of an alkyl group from one or more nucleotides within an DNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045958", "l": "positive regulation of complement activation, alternative pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002627", "l": "positive regulation of T cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0051017", "l": "actin filament bundle assembly", "d": ["The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010684", "l": "tricyclic triterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903761", "l": "negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003194", "l": "sinoatrial valve formation", "d": ["The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900932", "l": "regulation of nonadec-1-ene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0071971", "l": "extracellular exosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0002675", "l": "positive regulation of acute inflammatory response", "d": ["Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902955", "l": "positive regulation of early endosome to recycling endosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905716", "l": "negative regulation of cornification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cornification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003139", "l": "secondary heart field specification", "d": ["The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021608", "l": "accessory nerve formation", "d": ["The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904228", "l": "positive regulation of glycogen synthase activity, transferring glucose-1-phosphate", "d": ["Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003239", "l": "conus arteriosus morphogenesis", "d": ["The process in which the conus arteriosus is generated and organized. 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The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071866", "l": "negative regulation of apoptotic process in bone marrow cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070184", "l": "mitochondrial tyrosyl-tRNA aminoacylation", "d": ["The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010614", "l": "negative regulation of cardiac muscle hypertrophy", "d": ["Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061219", "l": "mesonephric mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048239", "l": "negative regulation of DNA recombination at telomere", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900727", "l": "osmoregulated periplasmic glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021707", "l": "cerebellar granule cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071679", "l": "commissural neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0000724", "l": "double-strand break repair via homologous recombination", "d": ["The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060879", "l": "semicircular canal fusion", "d": ["Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048600", "l": "oocyte fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903397", "l": "positive regulation of secondary cell septum biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070952", "l": "regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0046662", "l": "regulation of egg-laying behavior", "d": ["Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044874", "l": "lipoprotein localization to outer membrane", "d": ["A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900714", "l": "negative regulation of violaceol I biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032884", "l": "regulation of cell wall chitin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061244", "l": "mesonephric S-shaped body morphogenesis", "d": ["The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072037", "l": "mesenchymal stem cell differentiation involved in nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. 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This process mediates the entry of some non-enveloped virus into eukaryotic cells. In some cases, viral membrane-penetration protein requires to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0097009", "l": "energy homeostasis", "d": ["Any process involved in the balance between food intake (energy input) and energy expenditure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048648", "l": "caste determination", "d": ["The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. 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This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. 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Its ribonucleoside is known as inosine and its ribonucleotide as inosinate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.876091073600094", "identifiers": [{"i": "GO:0002820", "l": "negative regulation of adaptive immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006481", "l": "C-terminal protein methylation", "d": ["The methylation of the C-terminal amino acid of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0045589", "l": "regulation of regulatory T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900294", "l": "regulation of heptasaccharide transport", "d": ["Any process that modulates the frequency, rate or extent of heptasaccharide transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070147", "l": "mitochondrial cysteinyl-tRNA aminoacylation", "d": ["The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. 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of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000609", "l": "regulation of thyroid hormone generation", "d": ["Any process that modulates the frequency, rate or extent of thyroid hormone generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0008049", "l": "male courtship behavior", "d": ["The behavior of a male, for the purpose of attracting a sexual partner. 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Leucine import is the directed movement of leucine into a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060409", "l": "positive regulation of acetylcholine metabolic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. 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"peptidyl-thyronine biosynthetic process from peptidyl-tyrosine", "d": ["The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034192", "l": "D-galactonate metabolic process", "d": ["The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090421", "l": "embryonic meristem initiation", "d": ["Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1903084", "l": "protein localization to condensed nuclear 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"100", "identifiers": [{"i": "GO:0019610", "l": "3-hydroxyphenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070609", "l": "regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0120262", "l": "negative regulation of heterochromatin organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060367", "l": "sagittal suture morphogenesis", "d": ["The process in which the sagittal suture is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0043575", "l": "detection of osmotic stimulus", "d": ["The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.061263739914807", "identifiers": [{"i": "GO:0120036", "l": "plasma membrane bounded cell projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032953", "l": "regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0050802", "l": "circadian sleep/wake cycle, sleep", "d": ["The part of the circadian sleep/wake cycle where the organism is asleep."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021524", "l": "visceral motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. 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The trailing edge is the area of a motile cell opposite to the direction of movement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002558", "l": "type I hypersensitivity mediated by mast cells", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001954", "l": "positive regulation of cell-matrix adhesion", "d": ["Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.756196854933549", "identifiers": [{"i": "GO:0060541", "l": "respiratory system development", "d": ["The progression of the respiratory system over time from its formation to its mature structure. 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They are often found on or in the cell or tissue membranes and participate in a variety of biological activities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.682106400693733", "identifiers": [{"i": "GO:0048285", "l": "organelle fission", "d": ["The creation of two or more organelles by division of one organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002306", "l": "CD4-positive gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. 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This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:1990266", "l": "neutrophil migration", "d": ["The movement of a neutrophil within or between different tissues and organs of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0045944", "l": "positive regulation of transcription by RNA polymerase II", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090380", "l": "seed trichome maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009865", "l": "pollen tube adhesion", "d": ["The process in which the pollen tube adheres to cells of the stigma and style."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0048483", "l": "autonomic nervous system development", "d": ["The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. 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The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042541", "l": "hemoglobin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0106119", "l": "negative regulation of sterol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.084918961990851", "identifiers": [{"i": "GO:0090567", "l": "reproductive shoot system development", "d": ["The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0015740", "l": "C4-dicarboxylate transport", "d": ["The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048934", "l": "peripheral nervous system neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000626", "l": "negative regulation of miRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1902688", "l": "regulation of NAD metabolic process", "d": ["Any process that modulates the frequency, rate or extent of NAD metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0150107", "l": "positive regulation of protein localization to cell-cell junction", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036059", "l": "nephrocyte diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "43.526541869911121", "identifiers": [{"i": "GO:0007600", "l": "sensory perception", "d": ["The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905786", "l": "positive regulation of anaphase-promoting complex-dependent catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097750", "l": "endosome membrane tubulation", "d": ["A membrane tubulation process occurring in an endosome membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1902779", "l": "cellular response to alkane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001970", "l": "positive regulation of activation of membrane attack complex", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901829", "l": "zeaxanthin bis(beta-D-glucoside) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002738", "l": "positive regulation of plasmacytoid dendritic cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0002660", "l": "positive regulation of peripheral tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0002943", "l": "tRNA dihydrouridine synthesis", "d": ["The process whereby a uridine in a transfer RNA is converted to dihydrouridine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032763", "l": "regulation of mast cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of mast cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990910", "l": "response to hypobaric hypoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905608", "l": "positive regulation of presynapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of presynapse assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071400", "l": "cellular response to oleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0060856", "l": "establishment of blood-brain barrier", "d": ["Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.874891891299569", "identifiers": [{"i": "GO:0150063", "l": "visual system development", "d": ["The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044208", "l": "'de novo' AMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0009164", "l": "nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036171", "l": "filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905301", "l": "regulation of macropinocytosis", "d": ["Any process that modulates the frequency, rate or extent of macropinocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071277", "l": "cellular response to calcium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0005978", "l": "glycogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032832", "l": "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "44.530622889858655", "identifiers": [{"i": "GO:0006950", "l": "response to stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030709", "l": "border follicle cell delamination", "d": ["The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0006177", "l": "GMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.180713427975022", "identifiers": [{"i": "GO:0009411", "l": "response to UV", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. 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The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904553", "l": "negative regulation of chemotaxis to arachidonic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904933", "l": "regulation of cell proliferation in midbrain", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation in midbrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:1905332", "l": "positive regulation of morphogenesis of an epithelium", "d": ["Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900089", "l": "negative regulation of inositol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000536", "l": "negative regulation of entry of bacterium into host cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046296", "l": "glycolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021656", "l": "rhombomere 2 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 2. 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The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900078", "l": "positive regulation of cellular response to insulin stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903108", "l": "regulation of mitochondrial transcription", "d": ["Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0050979", "l": "magnetoreception by sensory perception of mechanical stimulus", "d": ["The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. 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Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902709", "l": "cellular response to plumbagin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0018108", "l": "peptidyl-tyrosine phosphorylation", "d": ["The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0021781", "l": "glial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell."], "t": 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which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904646", "l": "cellular response to amyloid-beta", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045315", "l": "positive regulation of compound eye photoreceptor development", "d": ["Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072701", "l": "cellular response to bismuth", "d": ["Any process that results in a change in state or activity of a cell (in terms of 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Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033552", "l": "response to vitamin B3", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003049", "l": "regulation of systemic arterial blood pressure by capillary fluid shift", "d": ["The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. 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Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003153", "l": "closure of embryonic heart tube", "d": ["Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0099533", "l": "positive regulation of presynaptic cytosolic calcium concentration", "d": ["Any process that increases the concentration of calcium ions in the presynaptic cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006241", "l": "CTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061249", "l": "mesonephric glomerular capillary formation", "d": ["The process that gives rise to a mesonephric glomerular capillary. 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Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032916", "l": "positive regulation of transforming growth factor beta3 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0033048", "l": "negative regulation of mitotic sister chromatid segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900609", "l": "F-9775A metabolic process", "d": ["The chemical reactions and pathways involving F-9775A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000032", "l": "regulation of secondary shoot formation", "d": ["Any process that modulates the frequency, rate or extent of secondary shoot formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032443", "l": "regulation of ergosterol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001136", "l": "negative regulation of endocytic recycling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046205", "l": "nor-spermidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021951", "l": "chemoattraction involved in precerebellar neuron migration", "d": ["The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904361", "l": "positive regulation of spore germination", "d": ["Any process that activates or increases the frequency, rate or extent of spore germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140540", "l": "negative regulation melanotic encapsulation of foreign target", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:1902750", "l": "negative regulation of cell cycle G2/M phase transition", "d": ["Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048345", "l": "regulation of paraxial mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060866", "l": "leaf abscission", "d": ["The controlled shedding of a leaf."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905350", "l": "Y-shaped link assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. 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The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000951", "l": "regulation of xyloglucan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of xyloglucan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000098", "l": "sulfur amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0140241", "l": "translation at synapse", "d": ["Translation that occurs at the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036504", "l": "Golgi membrane fusion", "d": ["The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071403", "l": "cellular response to high density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0006907", "l": "pinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. 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An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019661", "l": "glucose catabolic process to lactate via pyruvate", "d": ["The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905591", "l": "regulation of optical nerve axon regeneration", "d": ["Any process that modulates the frequency, rate or extent of optical nerve axon regeneration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003005", "l": "follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage", "d": ["The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904820", "l": "peritoneum development", "d": ["The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002419", "l": "T cell mediated cytotoxicity directed against tumor cell target", "d": ["The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007594", "l": "puparial adhesion", "d": ["The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098943", "l": "neurotransmitter receptor transport, postsynaptic endosome to lysosome", "d": ["The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0000460", "l": "maturation of 5.8S rRNA", "d": ["Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000301", "l": "negative regulation of synaptic vesicle exocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0010458", "l": "exit from mitosis", "d": ["The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035025", "l": "positive regulation of Rho protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0016138", "l": "glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0002865", "l": "negative regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036039", "l": "curcumin metabolic process", "d": ["The chemical reactions and pathways involving the polyphenol, curcumin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002373", "l": "plasmacytoid dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a plasmacytoid dendritic cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001149", "l": "negative regulation of dipeptide transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009154", "l": "purine ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0045861", "l": "negative regulation of proteolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0048334", "l": "regulation of mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of mesoderm cell fate determination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902836", "l": "positive regulation of proline import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of proline import into cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0072282", "l": "metanephric nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002606", "l": "positive regulation of dendritic cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000953", "l": "branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071263", "l": "negative regulation of translational initiation in response to starvation", "d": ["Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070141", "l": "response to UV-A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060214", "l": "endocardium formation", "d": ["Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045122", "l": "aflatoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048923", "l": "posterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0051712", "l": "positive regulation of killing of cells of another organism", "d": ["Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031247", "l": "actin rod assembly", "d": ["The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060907", "l": "positive regulation of macrophage cytokine production", "d": ["Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019611", "l": "4-toluenecarboxylate metabolic process", "d": ["The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019389", "l": "glucuronoside metabolic process", "d": ["The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061047", "l": "positive regulation of branching involved in lung morphogenesis", "d": ["Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902044", "l": "regulation of Fas signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of Fas signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904968", "l": "positive regulation of spindle attachment to meiosis I kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046070", "l": "dGTP metabolic process", "d": ["The chemical reactions and pathways involving dGTP, guanosine triphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072298", "l": "regulation of metanephric glomerulus development", "d": ["Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030164", "l": "protein denaturation", "d": ["Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042467", "l": "orthokinesis", "d": ["The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902958", "l": "positive regulation of mitochondrial electron transport, NADH to ubiquinone", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001199", "l": "negative regulation of dendritic cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901318", "l": "negative regulation of flagellated sperm motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032740", "l": "positive regulation of interleukin-17 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035509", "l": "negative regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010968", "l": "regulation of microtubule nucleation", "d": ["Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0160063", "l": "multi-pass transmembrane protein insertion into ER membrane", "d": ["A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. Insertion of multi-pass membrane proteins is mediated by the multi-pass translocon complex and takes place following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex to promote insertion of subsequent transmembrane regions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0015871", "l": "choline transport", "d": ["The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0014816", "l": "skeletal muscle satellite cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a satellite cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033661", "l": "effector-mediated defense to host-produced reactive oxygen species", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070092", "l": "regulation of glucagon secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of glucagon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042159", "l": "lipoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900170", "l": "negative regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903562", "l": "microtubule bundle formation involved in mitotic spindle midzone assembly", "d": ["Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.223947621509012", "identifiers": [{"i": "GO:0002520", "l": "immune system development", "d": ["The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015976", "l": "carbon utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048919", "l": "posterior lateral line neuromast development", "d": ["The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0014909", "l": "smooth muscle cell migration", "d": ["The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900578", "l": "gerfelin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gerfelin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904988", "l": "negative regulation of endothelial cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006864", "l": "pyrimidine nucleotide transport", "d": ["The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1903405", "l": "protein localization to nuclear body", "d": ["A process in which a protein is transported to, or maintained in, a location within a nuclear body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018306", "l": "iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.33144287441435", "identifiers": [{"i": "GO:0007338", "l": "single fertilization", "d": ["The union of male and female gametes to form a zygote."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0050772", "l": "positive regulation of axonogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of axonogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0017007", "l": "protein-bilin linkage", "d": ["The covalent linkage of bilin and a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001562", "l": "response to protozoan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0090715", "l": "immunological memory formation process", "d": ["Any immunological memory process that can contribute to the formation of immunological memory."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046802", "l": "exit of virus from host cell nucleus by nuclear egress", "d": ["The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. 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The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021798", "l": "forebrain dorsal/ventral pattern formation", "d": ["The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048912", "l": "glial cell migration in anterior lateral line nerve", "d": ["The movement of a glial cell along the axons in the anterior lateral line nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006167", "l": "AMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903925", "l": "response to bisphenol A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905192", "l": "regulation of chloroplast fission", "d": ["Any process that modulates the frequency, rate or extent of chloroplast fission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0032636", "l": "interleukin-7 production", "d": ["The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.847189235206869", "identifiers": [{"i": "GO:0098771", "l": "inorganic ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0019583", "l": "galactonate metabolic process", "d": ["The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0014002", "l": "astrocyte development", "d": ["The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. 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Docking requires only that the proteins come close enough to interact and adhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033311", "l": "chlorophyll a biosynthetic process via phytyl diphosphate", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.224433812983712", "identifiers": [{"i": "GO:0050912", "l": "detection of chemical stimulus involved in sensory perception of taste", "d": ["The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009631", "l": "cold acclimation", "d": ["Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0099543", "l": "trans-synaptic signaling by soluble gas", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.528207968973732", "identifiers": [{"i": "GO:0007635", "l": "chemosensory behavior", "d": ["Behavior that is dependent upon the sensation of chemicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019650", "l": "glycolytic fermentation to butanediol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0000972", "l": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "d": ["The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. 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Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070151", "l": "mitochondrial histidyl-tRNA aminoacylation", "d": ["The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. 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Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0033333", "l": "fin development", "d": ["The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.800315015132711", "identifiers": [{"i": "GO:0006357", "l": "regulation of transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070367", "l": "negative regulation of hepatocyte differentiation", "d": ["Any process that stops or decreases the rate 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Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903591", "l": "negative regulation of lysozyme activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0040028", "l": "regulation of vulval development", "d": ["Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018363", "l": "peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium", "d": ["The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0000744", "l": "karyogamy involved in conjugation with mutual genetic exchange", "d": ["During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070206", "l": "protein trimerization", "d": ["The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900483", "l": "regulation of protein targeting to vacuolar membrane", "d": ["Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904761", "l": "negative regulation of myofibroblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120291", "l": "negative regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033469", "l": "gibberellin 12 metabolic process", "d": ["The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044077", "l": "modulation by symbiont of host receptor-mediated endocytosis", "d": ["The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140040", "l": "mitochondrial polycistronic RNA processing", "d": ["The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035760", "l": "cytoplasmic polyadenylation-dependent rRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060764", "l": "cell-cell signaling involved in mammary gland development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034346", "l": "positive regulation of type III interferon production", "d": ["Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043100", "l": "pyrimidine nucleobase salvage", "d": ["Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000255", "l": "negative regulation of male germ cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900605", "l": "tensidol A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tensidol A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080142", "l": "regulation of salicylic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990575", "l": "mitochondrial L-ornithine transmembrane transport", "d": ["The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.301331245594", "identifiers": [{"i": "GO:0007584", "l": "response to nutrient", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140196", "l": "positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903277", "l": "negative regulation of sodium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904838", "l": "regulation of male germ-line stem cell asymmetric division", "d": ["Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.490486312819655", "identifiers": [{"i": "GO:0045777", "l": "positive regulation of blood pressure", "d": ["Any process in which the force of blood traveling through the circulatory system is increased."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0072351", "l": "tricarboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090437", "l": "socket cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0002016", "l": "regulation of blood volume by renin-angiotensin", "d": ["The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:1905809", "l": "negative regulation of synapse organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0045117", "l": "azole transmembrane transport", "d": ["The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010946", "l": "regulation of meiotic joint molecule formation", "d": ["Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061913", "l": "positive regulation of growth plate cartilage chondrocyte proliferation", "d": ["Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045729", "l": "respiratory burst at fertilization", "d": ["The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061616", "l": "glycolytic process from fructose through fructose-6-phosphate", "d": ["The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046281", "l": "cinnamic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002845", "l": "positive regulation of tolerance induction to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904392", "l": "cellular response to ciliary neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902176", "l": "negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901002", "l": "positive regulation of response to salt stress", "d": ["Any process that activates or increases the frequency, rate or extent of response to salt stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072743", "l": "cellular response to erythromycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001037", "l": "positive regulation of tongue muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043952", "l": "protein transport by the Sec complex", "d": ["The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072674", "l": "multinuclear osteoclast differentiation", "d": ["The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.74588611402384", "identifiers": [{"i": "GO:0042113", "l": "B cell activation", "d": ["The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902637", "l": "neural crest cell differentiation involved in thymus development", "d": ["Any neural crest cell differentiation that is involved in thymus development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060218", "l": "hematopoietic stem cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. 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The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033574", "l": "response to testosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060155", "l": "platelet dense granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901980", "l": "positive regulation of inward rectifier potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903823", "l": "telomere single strand break repair", "d": ["Single strand break repair that takes place in a telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0000912", "l": "assembly of actomyosin apparatus involved in cytokinesis", "d": ["The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:1902624", "l": "positive regulation of neutrophil migration", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:1901073", "l": "glucosamine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0042743", "l": "hydrogen peroxide metabolic process", "d": ["The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902785", "l": "cellular response to undecane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0000056", "l": "ribosomal small subunit export from nucleus", "d": ["The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033385", "l": "geranylgeranyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021896", "l": "forebrain astrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. 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Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0043534", "l": "blood vessel endothelial cell migration", "d": ["The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061378", "l": "corpora quadrigemina development", "d": ["The progression of the corpora quadrigemina over time, from its formation to the mature structure. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051979", "l": "alginic acid acetylation", "d": ["The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043103", "l": "hypoxanthine salvage", "d": ["Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0009292", "l": "horizontal gene transfer", "d": ["The introduction of genetic information into a cell to create a genetically different individual, without production of new individuals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.488468354030026", "identifiers": [{"i": "GO:0016042", "l": "lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048721", "l": "clypeus morphogenesis", "d": ["The process in which the anatomical structures of the clypeus are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010137", "l": "ureide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052168", "l": "modulation by symbiont of defense-related host calcium-dependent protein kinase pathway", "d": ["Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. 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The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0099638", "l": "endosome to plasma membrane protein transport", "d": ["The directed movement of proteins from the endosome to the plasma membrane in transport vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120312", "l": "ciliary basal body segregation", "d": ["The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. 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The capsid then disassembles, releasing the viral genome into the nucleoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002728", "l": "negative regulation of natural killer cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019280", "l": "L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039689", "l": "negative stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000525", "l": "positive regulation of T cell costimulation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell costimulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072238", "l": "metanephric long nephron development", "d": ["The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071497", "l": "cellular response to freezing", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.34152443344432", "identifiers": [{"i": "GO:0007049", "l": "cell cycle", "d": ["The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. 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An example of this process is found in Mus musculus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0015945", "l": "methanol metabolic process", "d": ["The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000845", "l": "positive regulation of testosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of testosterone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043051", "l": "regulation of nematode pharyngeal pumping", "d": ["Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002635", "l": "negative regulation of germinal center formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036522", "l": "negative regulation by symbiont of host protein localization to phagocytic vesicle", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000388", "l": "positive regulation of antral ovarian follicle growth", "d": ["Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990556", "l": "mitochondrial isopropylmalate transmembrane transport", "d": ["The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001175", "l": "transcriptional start site selection at RNA polymerase III promoter", "d": ["Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0016188", "l": "synaptic vesicle maturation", "d": ["Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0070507", "l": "regulation of microtubule cytoskeleton organization", "d": ["Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070156", "l": "mitochondrial phenylalanyl-tRNA aminoacylation", "d": ["The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. 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Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019354", "l": "siroheme biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0120276", "l": "regulation of cerebral blood circulation", "d": ["Any process that modulates the frequency, rate or extent of cerebral blood circulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0050708", "l": "regulation of protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021705", "l": "locus ceruleus formation", "d": ["The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0006516", "l": "glycoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.258850165314826", "identifiers": [{"i": "GO:0050974", "l": "detection of mechanical stimulus involved in sensory perception", "d": ["The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052574", "l": "UDP-galactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902021", "l": "regulation of bacterial-type flagellum-dependent cell motility", "d": ["Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:2000178", "l": "negative regulation of neural precursor cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900357", "l": "regulation of nigerotriose transport", "d": ["Any process that modulates the frequency, rate or extent of nigerotriose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0061228", "l": "mesonephric nephron morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric nephron are generated and organized. 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The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075242", "l": "negative regulation of zoospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036448", "l": "cellular response to glucose-phosphate stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0043308", "l": "eosinophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903006", "l": "positive regulation of protein K63-linked deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0099606", "l": "microtubule plus-end directed mitotic chromosome migration", "d": ["The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0032958", "l": "inositol phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990401", "l": "embryonic lung development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048797", "l": "swim bladder formation", "d": ["The process that gives rise to the swim bladder. 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These cells form the fibers that regulate cardiac muscle contraction in the ventricles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904943", "l": "negative regulation of cardiac ventricle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061614", "l": "miRNA transcription", "d": ["The cellular synthesis of microRNA (miRNA) transcripts. MicroRNA genes are synthesized as primary (pri) miRNA transcripts and subsequently processed to produce the ~22nt miRNAs that function in gene regulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070681", "l": "glutaminyl-tRNAGln biosynthesis via transamidation", "d": ["A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0035933", "l": "glucocorticoid secretion", "d": ["The regulated release of any glucocorticoid hormone into the circulatory system. 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An example of this process is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003098", "l": "tubuloglomerular feedback", "d": ["The process in which blood volume is regulated due to a change in the rate of glomerular filtration. 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Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033467", "l": "CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process", "d": ["The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010434", "l": "bract formation", "d": ["The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0007031", "l": "peroxisome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.156270827921489", "identifiers": [{"i": "GO:0048565", "l": "digestive tract development", "d": ["The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. 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The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061099", "l": "negative regulation of protein tyrosine kinase activity", "d": ["Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061734", "l": "parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0099547", "l": "regulation of translation at synapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080191", "l": "secondary thickening", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0036090", "l": "cleavage furrow ingression", "d": ["Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. 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Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.084918961990851", "identifiers": [{"i": "GO:0007162", "l": "negative regulation of cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.834096184795619", "identifiers": [{"i": "GO:0048762", "l": "mesenchymal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010621", "l": "negative regulation of transcription by transcription factor localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035781", "l": "CD86 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905183", "l": "negative regulation of protein serine/threonine phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060948", "l": "cardiac vascular smooth muscle cell development", "d": ["The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0150202", "l": "negative regulation of transport across blood-brain barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0032367", "l": "intracellular cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900671", "l": "negative regulation of F-9775A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000546", "l": "positive regulation of endothelial cell chemotaxis to fibroblast growth factor", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002074", "l": "extraocular skeletal muscle development", "d": ["The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045985", "l": "positive regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015826", "l": "threonine transport", "d": ["The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0042161", "l": "lipoprotein oxidation", "d": ["The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021811", "l": "growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration", "d": ["Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002105", "l": "endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1903573", "l": "negative regulation of response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010198", "l": "synergid death", "d": ["Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0002293", "l": "alpha-beta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045966", "l": "positive regulation of ecdysteroid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060174", "l": "limb bud formation", "d": ["The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110023", "l": "negative regulation of cardiac muscle myoblast proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060608", "l": "cell-cell adhesion involved in neural tube closure", "d": ["The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1900076", "l": "regulation of cellular response to insulin stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.34709754747162", "identifiers": [{"i": "GO:0001932", "l": "regulation of protein phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0014902", "l": "myotube differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. 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Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062227", "l": "positive regulation of adult somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of adult somatic muscle development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080193", "l": "diffuse secondary thickening", "d": ["Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1990986", "l": "DNA recombinase disassembly", "d": ["The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0002066", "l": "columnar/cuboidal epithelial cell development", "d": ["The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903885", "l": "negative regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018221", "l": "peptidyl-serine palmitoylation", "d": ["The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900648", "l": "positive regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060489", "l": "planar dichotomous subdivision of terminal units involved in lung branching morphogenesis", "d": ["The process in which a lung bud bifurcates parallel to the plane of the previous bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006680", "l": "glucosylceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009192", "l": "deoxyribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097088", "l": "interleukin-17F production", "d": ["The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141030", "l": "symbiont-mediated perturbation of host actin cytoskeleton via filamentous actin depolymerization", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by depolymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0008069", "l": "dorsal/ventral axis specification, ovarian follicular epithelium", "d": ["Polarization of the ovarian follicle cells along the dorsal/ventral axis. 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Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000769", "l": "syncytium formation by mitosis without cytokinesis", "d": ["The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043479", "l": "pigment accumulation in tissues in response to UV light", "d": ["The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048346", "l": "positive regulation of paraxial mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.161717068681156", "identifiers": [{"i": "GO:0051180", "l": "vitamin transport", "d": ["The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0001949", "l": "sebaceous gland cell differentiation", "d": ["The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990478", "l": "response to ultrasound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042919", "l": "benzoate transport", "d": ["The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900502", "l": "positive regulation of butyryl-CoA catabolic process to butyrate", "d": ["Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002155", "l": "regulation of thyroid hormone mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002595", "l": "regulation of antigen processing and presentation of 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"identifiers": [{"i": "GO:0042269", "l": "regulation of natural killer cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904699", "l": "positive regulation of acinar cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of acinar cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990466", "l": "protein autosumoylation", "d": ["The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051454", "l": "intracellular pH elevation", "d": ["Any process that increases the internal pH of a cell, measured by the 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This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031991", "l": "regulation of actomyosin contractile ring contraction", "d": ["Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0000921", "l": "septin ring assembly", "d": ["The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160024", "l": "Leydig cell proliferation", "d": ["The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. 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Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046723", "l": "malic acid secretion", "d": ["The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070329", "l": "tRNA seleno-modification", "d": ["The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904662", "l": "positive regulation of sensory perception of bitter taste", "d": ["Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.34709754747162", "identifiers": [{"i": "GO:0070293", "l": "renal absorption", "d": ["A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106289", "l": "negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042671", "l": "retinal cone cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044652", "l": "adhesion of symbiont to host endothelial cell", "d": ["The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903626", "l": "positive regulation of DNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of DNA catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905908", "l": "positive regulation of amyloid fibril formation", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid fibril formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090464", "l": "intracellular histidine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of histidine within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0035746", "l": "granzyme A production", "d": ["The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018082", "l": "peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine", "d": ["The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001038", "l": "regulation of cellular response to drug", "d": ["Any process that modulates the frequency, rate or extent of cellular response to drug."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0050770", "l": "regulation of axonogenesis", "d": ["Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.79931926293068", "identifiers": [{"i": "GO:0071887", "l": "leukocyte apoptotic process", "d": ["Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032293", "l": "non-myelinated axon ensheathment in central nervous system", "d": ["The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0080155", "l": "regulation of double fertilization forming a zygote and endosperm", "d": ["Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. 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An example of this component is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120069", "l": "positive regulation of stomach fundus smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.181923218402147", "identifiers": [{"i": "GO:0033013", "l": "tetrapyrrole metabolic process", "d": ["The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0010455", "l": "positive regulation of cell fate commitment", "d": ["Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.912498735596799", "identifiers": [{"i": "GO:0043414", "l": "macromolecule methylation", "d": ["The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0003231", "l": "cardiac ventricle development", "d": ["The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035285", "l": "appendage segmentation", "d": ["Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:1903666", "l": "positive regulation of asexual reproduction", "d": ["Any process that activates or increases the frequency, rate or extent of asexual reproduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905852", "l": "positive regulation of backward locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of backward locomotion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045722", "l": "positive regulation of gluconeogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of gluconeogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008586", "l": "imaginal disc-derived wing vein morphogenesis", "d": ["The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0032073", "l": "negative regulation of restriction endodeoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0022011", "l": "myelination in peripheral nervous system", "d": ["The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0010359", "l": "regulation of anion channel activity", "d": ["Any process that modulates the frequency, rate or extent of anion channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001572", "l": "lactosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901093", "l": "regulation of protein homotetramerization", "d": ["Any process that modulates the frequency, rate or extent of protein homotetramerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001224", "l": "positive regulation of neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of neuron migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002084", "l": "protein depalmitoylation", "d": ["The removal of palymitoyl groups from a lipoprotein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018172", "l": "peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.023409404909437", "identifiers": [{"i": "GO:0030072", "l": "peptide hormone secretion", "d": ["The regulated release of a peptide hormone from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021616", "l": "glossopharyngeal nerve formation", "d": ["The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0010719", "l": "negative regulation of epithelial to mesenchymal transition", "d": ["Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0035809", "l": "regulation of urine volume", "d": ["Any process that modulates the amount of urine excreted from the body over a unit of time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014732", "l": "skeletal muscle atrophy", "d": ["A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034195", "l": "L-galactonate catabolic 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"biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:1901378", "l": "organic heteropentacyclic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902800", "l": "positive regulation of phosphodiesterase I activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071548", "l": "response to dexamethasone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": 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There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000086", "l": "positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901592", "l": "negative regulation of double-strand break repair via break-induced replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.915726484813547", "identifiers": [{"i": "GO:0043010", "l": "camera-type eye development", "d": ["The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. 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trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:2000028", "l": "regulation of photoperiodism, flowering", "d": ["Any process that modulates the frequency, rate or extent of photoperiodism, flowering."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007430", "l": "terminal branching, open tracheal system", "d": ["Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046062", "l": "dCDP metabolic process", "d": ["The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:1901655", "l": "cellular response to ketone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051906", "l": "maintenance of pigment granule location", "d": ["Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904627", "l": "response to phorbol 13-acetate 12-myristate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000703", "l": "negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071486", "l": "cellular response to high light intensity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0006368", "l": "transcription elongation by RNA polymerase II", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0007113", "l": "endomitotic cell cycle", "d": ["A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021514", "l": "ventral spinal cord interneuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1990166", "l": "protein localization to site of double-strand break", "d": ["Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018919", "l": "gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:1903436", "l": "regulation of mitotic cytokinetic process", "d": ["Any process that modulates the frequency, rate or extent of mitotic cytokinetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000347", "l": "positive regulation of hepatocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140991", "l": "piRNA-mediated gene silencing by mRNA destabilization", "d": ["A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900235", "l": "negative regulation of Kit signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160022", "l": "apocrine secretion", "d": ["The controlled release of a substance by a cell or a tissue by discharging a portion of the secreting cell when intracellular components are freed into a lumen through the shedding of whole pieces of the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110027", "l": "negative regulation of DNA strand resection involved in replication fork processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048774", "l": "cyanophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. 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The pigment is stored in fibrous organelles termed cyanosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009413", "l": "response to flooding", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009239", "l": "enterobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0002794", "l": "regulation of antimicrobial peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900809", "l": "fumigaclavine C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumigaclavine C, a fungal ergot alkaloid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001035", "l": "regulation of tongue muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160019", "l": "negative regulation of platelet rolling", "d": ["Any process that decreases the rate, frequency, or extent of platelet rolling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.741169254015119", "identifiers": [{"i": "GO:0031331", "l": "positive regulation of cellular catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045049", "l": "protein insertion into ER membrane by N-terminal cleaved signal sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904316", "l": "response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018062", "l": "peptidyl-tryptophan succinylation", "d": ["The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021601", "l": "abducens nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034163", "l": "regulation of toll-like receptor 9 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045602", "l": "negative regulation of endothelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009396", "l": "folic acid-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of folic acid and its derivatives."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0002260", "l": "lymphocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032083", "l": "negative regulation of type IV site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071239", "l": "cellular response to streptomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905853", "l": "regulation of heparan sulfate binding", "d": ["Any process that modulates the frequency, rate or extent of heparan sulfate binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.796139606449842", "identifiers": [{"i": "GO:0048515", "l": "spermatid differentiation", "d": ["The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0007293", "l": "germarium-derived egg chamber formation", "d": ["Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0042748", "l": "circadian sleep/wake cycle, non-REM sleep", "d": ["All sleep stages in the circadian sleep/wake cycle other than REM sleep. 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It also acts as a paracrine signal in various non-neural tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905085", "l": "regulation of bioluminescence", "d": ["Any process that modulates the frequency, rate or extent of bioluminescence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0097087", "l": "interleukin-17A production", "d": ["The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1904105", "l": "positive regulation of convergent extension involved in gastrulation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061509", "l": "asymmetric protein localization to old mitotic spindle pole body", "d": ["Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.130494968946721", "identifiers": [{"i": "GO:0019439", "l": "aromatic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003317", "l": "cardioblast cell midline fusion", "d": ["The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046220", "l": "pyridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006203", "l": "dGTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001204", "l": "regulation of osteoclast development", "d": ["Any process that modulates the frequency, rate or extent of osteoclast development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000264", "l": "negative regulation of blood coagulation, extrinsic pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030494", "l": "bacteriochlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. 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"l": "positive regulation of dopamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019462", "l": "glutamine catabolic process to fumarate, using glutaminase", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903851", "l": "negative regulation of cristae formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003043", "l": "vasoconstriction of artery involved in 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discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021645", "l": "vagus nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051330", "l": "meiotic G1 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905089", "l": "regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050903", "l": "leukocyte activation-dependent arrest", "d": ["The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071313", "l": "cellular response to caffeine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0097707", "l": "ferroptosis", "d": ["A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0034758", "l": "positive regulation of iron ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097436", "l": "entry into dormancy", "d": ["The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006001", "l": "fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.915726484813547", "identifiers": [{"i": "GO:0030537", "l": "larval behavior", "d": ["Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903251", "l": "multi-ciliated epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0006577", "l": "amino-acid betaine metabolic process", "d": ["The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060792", "l": "sweat gland development", "d": ["The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0097280", "l": "histamine secretion mediated by immunoglobulin", "d": ["Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990514", "l": "5' transitive RNA interference", "d": ["An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901541", "l": "ent-pimara-8(14),15-diene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048210", "l": "Golgi vesicle fusion to target membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0009813", "l": "flavonoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0001833", "l": "inner cell mass cell proliferation", "d": ["The proliferation of cells in the inner cell mass."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905404", "l": "positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000718", "l": "regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901061", "l": "guaiacyl lignin metabolic process", "d": ["The chemical reactions and pathways involving guaiacyl lignin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900325", "l": "negative regulation of maltotriulose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000629", "l": "negative regulation of miRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006157", "l": "deoxyadenosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905193", "l": "negative regulation of chloroplast fission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0021761", "l": "limbic system development", "d": ["The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0001796", "l": "regulation of type IIa hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033864", "l": "positive regulation of NAD(P)H oxidase activity", "d": ["Any process that activates or increases the activity of the enzyme NAD(P)H oxidase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0097711", "l": "ciliary basal body-plasma membrane docking", "d": ["The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane."], "t": []}, {"i": "REACT:R-HSA-5620912.1", "d": [], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140528", "l": "bilobe structure assembly", "d": ["The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030241", "l": "skeletal muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001720", "l": "conversion of lysyl-tRNA to pyrrolysyl-tRNA", "d": ["The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0006891", "l": "intra-Golgi vesicle-mediated transport", "d": ["The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:1902305", "l": "regulation of sodium ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0051224", "l": "negative regulation of protein transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.301331245594", "identifiers": [{"i": "GO:0007015", "l": "actin filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051611", "l": "regulation of serotonin uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.215234746075474", "identifiers": [{"i": "GO:1901135", "l": "carbohydrate derivative metabolic process", "d": ["The chemical reactions and pathways involving carbohydrate derivative."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905101", "l": "negative regulation of apoptosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0030178", "l": "negative regulation of Wnt signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905946", "l": "negative regulation of response to calcium ion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090445", "l": "positive regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070843", "l": "misfolded protein transport", "d": ["The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1903817", "l": "negative regulation of voltage-gated potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903344", "l": "regulation of protein polyglycylation", "d": ["Any process that modulates the frequency, rate or extent of protein polyglycylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010944", "l": "negative regulation of transcription by competitive promoter binding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:1903076", "l": "regulation of protein localization to plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0034644", "l": "cellular response to UV", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006173", "l": "dADP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007394", "l": "dorsal closure, elongation of leading edge cells", "d": ["The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "17.294417412473322", "identifiers": [{"i": "GO:0006518", "l": "peptide metabolic process", "d": ["The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002076", "l": "osteoblast development", "d": ["The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. 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This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0099504", "l": "synaptic vesicle cycle", "d": ["A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032752", "l": "positive regulation of interleukin-3 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-3 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0071963", "l": "establishment or maintenance of cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070624", "l": "negative regulation of thiamine biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0140267", "l": "symbiont entry into host cell via permeabilization of host membrane", "d": ["The entry of a symbiont into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration symbiont protein. 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expression, etc.) as a result of a vitamin A stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.505860269213017", "identifiers": [{"i": "GO:0090407", "l": "organophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0099175", "l": "regulation of postsynapse organization", "d": ["Any process that modulates the physical form of a postsynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000091", "l": "negative regulation of mesonephric glomerular mesangial cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061058", "l": "regulation of peptidoglycan recognition protein signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0051881", "l": "regulation of mitochondrial membrane potential", "d": ["Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075529", "l": "establishment of latency as a circular episome", "d": ["A process by which a virus establishes a latent state within 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001769", "l": "establishment of B cell polarity", "d": ["The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045209", "l": "MAPK phosphatase export from nucleus, leptomycin B sensitive", "d": ["Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0030809", "l": "negative regulation of nucleotide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030965", "l": "plasma membrane electron transport, NADH to quinone", "d": ["The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0045433", "l": "male courtship behavior, veined wing generated song production", "d": ["The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000400", "l": "positive regulation of thymocyte aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060176", "l": "regulation of aggregation involved in sorocarp development", "d": ["Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. 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The aggregate is a multicellular structure that gives rise to the slug."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0061718", "l": "glucose catabolic process to pyruvate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072138", "l": "mesenchymal cell proliferation involved in ureteric bud development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001309", "l": "gliotoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901158", "l": "neomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neomycin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0048364", "l": "root development", "d": ["The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901965", "l": "endoplasmic reticulum to chloroplast transport", "d": ["The directed movement of substances from endoplasmic reticulum to chloroplast."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044601", "l": "protein denucleotidylation", "d": ["The removal of a nucleotide from a protein amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901398", "l": "regulation of transforming growth factor beta3 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097439", "l": "acquisition of desiccation tolerance", "d": ["The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901904", "l": "tyrocidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tyrocidine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990564", "l": "protein polyufmylation", "d": ["Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900177", "l": "regulation of aflatoxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002727", "l": "regulation of natural killer cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048722", "l": "anterior cibarial plate development", "d": ["The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0001975", "l": "response to amphetamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006015", "l": "5-phosphoribose 1-diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0010325", "l": "raffinose family oligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.20033635754347", "identifiers": [{"i": "GO:0003014", "l": "renal system process", "d": ["A organ system process carried out by any of the organs or tissues of the renal system. 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The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000342", "l": "negative regulation of chemokine (C-X-C motif) ligand 2 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900676", "l": "negative regulation of F-9775B biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046884", "l": "follicle-stimulating hormone secretion", "d": ["The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033544", "l": "fatty acid beta-oxidation, unsaturated, even number, epimerase pathway", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048713", "l": "regulation of oligodendrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044029", "l": "positive regulation of gene expression via CpG island demethylation", "d": ["An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904337", "l": "positive regulation of ductus arteriosus closure", "d": ["Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097166", "l": "lens epithelial cell proliferation", "d": ["The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901259", "l": "chloroplast rRNA processing", "d": ["Any rRNA processing that takes place in chloroplast."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0099525", "l": "presynaptic dense core vesicle exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033527", "l": "tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0035266", "l": "meristem growth", "d": ["The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0003203", "l": "endocardial cushion morphogenesis", "d": ["The process in which the anatomical structure of the endocardial cushion is generated and organized. 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A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990417", "l": "snoRNA release from pre-rRNA", "d": ["The release of snoRNA from pre-rRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0039021", "l": "pronephric glomerulus development", "d": ["The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032487", "l": "regulation of Rap protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rap protein signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051522", "l": "activation of monopolar cell growth", "d": ["Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0045472", "l": "response to ether", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902510", "l": "regulation of apoptotic DNA fragmentation", "d": ["Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048537", "l": "mucosa-associated lymphoid tissue development", "d": ["The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052036", "l": "suppression by symbiont of host inflammatory response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010884", "l": "positive regulation of lipid storage", "d": ["Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902056", "l": "(25S)-Delta(7)-dafachronate metabolic process", "d": ["The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0000429", "l": "carbon catabolite regulation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0097421", "l": "liver regeneration", "d": ["The regrowth of lost or destroyed liver."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043508", "l": "negative regulation of JUN kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002398", "l": "MHC class Ib protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051999", "l": "mannosyl-inositol phosphorylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0016048", "l": "detection of temperature stimulus", "d": ["The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046118", "l": "7-methylguanosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0061438", "l": "renal system vasculature morphogenesis", "d": ["The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903783", "l": "negative regulation of sodium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901614", "l": "positive regulation of terminal button organization", "d": ["Any process that activates or increases the frequency, rate or extent of terminal button organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014043", "l": "negative regulation of neuron maturation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901871", "l": "ecgonone methyl ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0009200", "l": "deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072279", "l": "convergent extension involved in metanephric nephron morphogenesis", "d": ["The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035167", "l": "larval lymph gland hemopoiesis", "d": ["The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002107", "l": "generation of mature 3'-end of 5S rRNA generated by RNA polymerase III", "d": ["The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072066", "l": "prebend segment development", "d": ["The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019266", "l": "asparagine biosynthetic process from oxaloacetate", "d": ["The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.14133299147904", "identifiers": [{"i": "GO:0051241", "l": "negative regulation of multicellular organismal process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045863", "l": "negative regulation of pteridine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018014", "l": "N-terminal peptidyl-methionine methylation", "d": ["The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000335", "l": "regulation of endothelial microparticle formation", "d": ["Any process that modulates the frequency, rate or extent of endothelial microparticle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000480", "l": "negative regulation of cAMP-dependent protein kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901211", "l": "negative regulation of cardiac chamber formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090425", "l": "acinar cell differentiation", "d": ["The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009047", "l": "dosage compensation by hyperactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0070169", "l": "positive regulation of biomineral tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.249098858391747", "identifiers": [{"i": "GO:0051168", "l": "nuclear export", "d": ["The directed movement of substances out of the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000380", "l": "regulation of mesoderm development", "d": ["Any process that modulates the frequency, rate or extent of mesoderm development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904796", "l": "regulation of core promoter binding", "d": ["Any process that modulates the frequency, rate or extent of core promoter binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046206", "l": "trypanothione metabolic process", "d": ["The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090707", "l": "establishment of plant organ orientation", "d": ["The process that determines the orientation of a plant organ or tissue with reference to an axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.2284025111056", "identifiers": [{"i": "GO:0051223", "l": "regulation of protein transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061098", "l": "positive regulation of protein tyrosine kinase activity", "d": ["Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0031537", "l": "regulation of anthocyanin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075606", "l": "transport of viral material towards nucleus", "d": ["The directed movement of a virus, or part of a virus, towards the host cell nucleus. 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Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903582", "l": "negative regulation of basophil degranulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045608", "l": "negative regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902147", "l": "regulation of response to cytokinesis checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015943", "l": "formate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:0000096", "l": "sulfur amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021822", "l": "negative regulation of cell motility involved in cerebral cortex radial glia guided migration", "d": ["The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014711", "l": "regulation of branchiomeric skeletal muscle development", "d": ["Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. 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Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072198", "l": "mesenchymal cell proliferation involved in ureter development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019096", "l": "pole plasm mitochondrial lrRNA localization", "d": ["Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. 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Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070070", "l": "proton-transporting V-type ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901929", "l": "alpha-copaene metabolic process", "d": ["The chemical reactions and pathways involving alpha-copaene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.186222083173888", "identifiers": [{"i": "GO:1901293", "l": "nucleoside phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.713478367176648", "identifiers": [{"i": "GO:0048812", "l": "neuron projection morphogenesis", "d": ["The process in which the anatomical structures of a neuron projection are generated and organized. 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It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902771", "l": "positive regulation of choline O-acetyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0050843", "l": "S-adenosylmethionine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.399278032977378", "identifiers": [{"i": "GO:0034101", "l": "erythrocyte homeostasis", "d": ["Any process of regulating the production and elimination of erythrocytes within an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021858", "l": "GABAergic neuron differentiation in basal ganglia", "d": ["The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. 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"identifiers": [{"i": "GO:1901998", "l": "toxin transport", "d": ["The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008615", "l": "pyridoxine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905498", "l": "positive regulation of triplex DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of triplex DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905362", "l": "negative regulation of endosomal vesicle fusion", "d": ["Any process that stops, prevents 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Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045325", "l": "peptidyl-tryptophan hydroxylation", "d": ["The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050930", "l": "induction of positive chemotaxis", "d": ["Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.300845054119293", "identifiers": [{"i": "GO:0007617", "l": "mating behavior", "d": ["The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046927", "l": "peptidyl-threonine racemization", "d": ["The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. 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Venous blood vessels carry blood back to the heart after the capillary bed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090379", "l": "secondary cell wall biogenesis involved in seed trichome differentiation", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0150078", "l": "positive regulation of neuroinflammatory response", "d": ["Any process that activates or increases the frequency, rate or extent of neuroinflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0061512", "l": "protein localization to cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a cilium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0031048", "l": "regulatory ncRNA-mediated heterochromatin formation", "d": ["A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginnning of trancription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009903", "l": "chloroplast avoidance movement", "d": ["The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1902093", "l": "positive regulation of flagellated sperm motility", "d": ["Any process that activates or increases the frequency, rate or extent of flagellated sperm motility."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904249", "l": "negative regulation of age-related resistance", "d": ["Any process that stops, prevents or reduces the extent of age-related resistance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0021979", "l": "hypothalamus cell differentiation", "d": ["The differentiation of cells that will contribute to the structure and function of the hypothalamus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045208", "l": "MAPK phosphatase export from nucleus", "d": ["The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048904", "l": "anterior lateral line neuromast cupula development", "d": ["The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1901269", "l": "lipooligosaccharide metabolic process", "d": ["The chemical reactions and pathways involving lipooligosaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009372", "l": "quorum sensing", "d": ["The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. 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The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:1904950", "l": "negative regulation of establishment of protein localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042777", "l": "proton motive force-driven plasma membrane ATP synthesis", "d": ["The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0070897", "l": "transcription preinitiation complex assembly", "d": ["The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC). The PIC engages the RNA polymerase on its DNA template strand and sparks polymerization of the first few RNA nucleotides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0002256", "l": "regulation of kinin cascade", "d": ["Any process that modulates the frequency, rate, or extent of the kinin cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010377", "l": "guard cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. 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This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000863", "l": "positive regulation of estrogen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estrogen secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0009834", "l": "plant-type secondary cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071643", "l": "regulation of chemokine (C-C motif) ligand 4 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.917179239854292", "identifiers": [{"i": "GO:0046032", "l": "ADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046603", "l": "negative regulation of mitotic centrosome separation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0098720", "l": "succinate import across plasma membrane", "d": ["The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900851", "l": "positive regulation of pseurotin A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018268", "l": "GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035313", "l": "wound healing, spreading of epidermal cells", "d": ["The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031426", "l": "polycistronic mRNA processing", "d": ["The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062038", "l": "positive regulation of pheromone response MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000195", "l": "negative regulation of female gonad development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904902", "l": "ESCRT III complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.56897143071847", "identifiers": [{"i": "GO:0008015", "l": "blood circulation", "d": ["The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1990735", "l": "gamma-tubulin complex localization to mitotic spindle pole body", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001781", "l": "neutrophil apoptotic process", "d": ["Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0046864", "l": "isoprenoid transport", "d": ["The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032491", "l": "detection of molecule of fungal origin", "d": ["The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905447", "l": "negative regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035756", "l": "symbiont-mediated migration through host transepithelium", "d": ["A process in which a symbiont moves from one side of an epithelium to the other within its host organism. 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It is a member of the B complex of vitamins and occurs widely in living organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900205", "l": "apoptotic process involved in metanephric nephron tubule development", "d": ["Any apoptotic process that is involved in metanephric nephron tubule development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001232", "l": "positive regulation of protein localization to prospore membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901491", "l": "negative regulation of lymphangiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032207", "l": "regulation of telomere maintenance via recombination", "d": ["Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051791", "l": "medium-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a medium-chain fatty acid. 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When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.014330232248525", "identifiers": [{"i": "GO:0097529", "l": "myeloid leukocyte migration", "d": ["The movement of a myeloid leukocyte within or between different tissues and organs of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.756683046408256", "identifiers": [{"i": "GO:0170038", "l": "proteinogenic amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007221", "l": "positive regulation of transcription of Notch receptor target", "d": ["The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002942", "l": "tRNA m2,2-guanine biosynthesis", "d": ["The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0015011", "l": "nickel-tetrapyrrole coenzyme metabolic process", "d": ["The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051363", "l": "peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein", "d": ["The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0002089", "l": "lens morphogenesis in camera-type eye", "d": ["The process in which the anatomical structures of the lens are generated and organized. 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Corneal endothelium is a special case, derived from neural crest cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010360", "l": "negative regulation of anion channel activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0010950", "l": "positive regulation of endopeptidase activity", "d": ["Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.672771840408203", "identifiers": [{"i": "GO:0007143", "l": "female meiotic nuclear division", "d": ["A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046216", "l": "indole phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035124", "l": "embryonic caudal fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.249098858391747", "identifiers": [{"i": "GO:0010975", "l": "regulation of neuron projection development", "d": ["Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060701", "l": "negative regulation of ribonuclease activity", "d": ["Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036273", "l": "response to statin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000648", "l": "positive regulation of stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of stem cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0016106", "l": "sesquiterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0003357", "l": "noradrenergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044720", "l": "negative regulation of imaginal disc-derived wing size", "d": ["Any process that reduces the size of an imaginal disc-derived wing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:1904018", "l": "positive regulation of vasculature development", "d": ["Any process that activates or increases the frequency, rate or extent of vasculature development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0080145", "l": "intracellular cysteine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of cysteine within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071587", "l": "CAAX-box protein modification", "d": ["The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062210", "l": "shoot regeneration", "d": ["The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021745", "l": "nucleus ambiguus development", "d": ["The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075241", "l": "positive regulation of zoospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0016118", "l": "carotenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.150839206632412", "identifiers": [{"i": "GO:0016070", "l": "RNA metabolic process", "d": ["The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060328", "l": "cytoplasmic actin-based contraction involved in forward cell motility", "d": ["The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006627", "l": "protein processing involved in protein targeting to mitochondrion", "d": ["The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0030901", "l": "midbrain development", "d": ["The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:2001236", "l": "regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010344", "l": "seed oilbody biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.528207968973732", "identifiers": [{"i": "GO:0009410", "l": "response to xenobiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0071027", "l": "nuclear RNA surveillance", "d": ["A process that identifies and degrades defective or aberrant RNAs within the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034402", "l": "recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex", "d": ["The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048907", "l": "anterior lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048902", "l": "anterior lateral line neuromast deposition", "d": ["The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035343", "l": "negative regulation of inosine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "45.28752044856239", "identifiers": [{"i": "GO:0007610", "l": "behavior", "d": ["The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900216", "l": "positive regulation of apoptotic process involved in metanephric collecting duct development", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0019685", "l": "photosynthesis, dark reaction", "d": ["A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036378", "l": "calcitriol biosynthetic process from calciol", "d": ["Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0110017", "l": "cap-independent translational initiation of linear mRNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036331", "l": "avascular cornea development in camera-type eye", "d": ["The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.335082997926719", "identifiers": [{"i": "GO:0006887", "l": "exocytosis", "d": ["A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009763", "l": "NAD-malic enzyme C4 photosynthesis", "d": ["The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900577", "l": "gerfelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gerfelin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0018970", "l": "toluene metabolic process", "d": ["The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000865", "l": "negative regulation of estradiol secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071250", "l": "cellular response to nitrite", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.661675958401567", "identifiers": [{"i": "GO:0019748", "l": "secondary metabolic process", "d": ["The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031293", "l": "membrane protein intracellular domain proteolysis", "d": ["The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021712", "l": "candelabrum cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033029", "l": "regulation of neutrophil apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905497", "l": "negative regulation of triplex DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009640", "l": "photomorphogenesis", "d": ["The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0051984", "l": "positive regulation of chromosome segregation", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0031102", "l": "neuron projection regeneration", "d": ["The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000489", "l": "regulation of hepatic stellate cell activation", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901177", "l": "lycopene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lycopene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032666", "l": "regulation of interleukin-22 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-22 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051563", "l": "smooth endoplasmic reticulum calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0001936", "l": "regulation of endothelial cell proliferation", "d": ["Any process that modulates the frequency, rate, or extent of endothelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018009", "l": "N-terminal peptidyl-L-cysteine N-palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003288", "l": "ventricular septum intermedium morphogenesis", "d": ["The developmental process in which a ventricular septum intermedium is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0071825", "l": "protein-lipid complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0022012", "l": "subpallium cell proliferation in forebrain", "d": ["The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0001865", "l": "NK T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a NK T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051501", "l": "diterpene phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.773102578641854", "identifiers": [{"i": "GO:0031175", "l": "neuron projection development", "d": ["The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903242", "l": "regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051355", "l": "proprioception involved in equilibrioception", "d": ["The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. 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Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903815", "l": "negative regulation of collecting lymphatic vessel constriction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904387", "l": "cellular response to L-phenylalanine derivative", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009050", "l": "glycopeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.33144287441435", "identifiers": [{"i": "GO:0002514", "l": "B cell tolerance induction", "d": ["A process involving any mechanism for tolerance induction in B cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0018085", "l": "peptidyl-L-amino acid racemization", "d": ["The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007429", "l": "secondary branching, open tracheal system", "d": ["Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. 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An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. 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A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071908", "l": "determination of intestine left/right asymmetry", "d": ["Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010258", "l": "NADH dehydrogenase complex (plastoquinone) assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010555", "l": "response to mannitol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902751", "l": "positive regulation of cell cycle G2/M phase transition", "d": ["Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039580", "l": "symbiont-mediated suppression of host PKR/eIFalpha signaling", "d": ["A process in which a symbiont inhibits or disrupts a host PKR (Protein Kinase regulated by RNA) signaling. 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The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0033077", "l": "T cell differentiation in thymus", "d": ["The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003050", "l": "regulation of systemic arterial blood pressure by atrial natriuretic peptide", "d": ["The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044808", "l": "oncostatin M production", "d": ["The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.944488487207011", "identifiers": [{"i": "GO:0040029", "l": "epigenetic regulation of gene expression", "d": ["A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. 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It can also be heritable in the absence of the instigating signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006035", "l": "cuticle chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043031", "l": "negative regulation of macrophage activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042397", "l": "phosphagen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905247", "l": "positive regulation of aspartic-type peptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090625", "l": "siRNA-mediated gene silencing by mRNA destabilization", "d": ["An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. 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The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002091", "l": "negative regulation of receptor internalization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044179", "l": "hemolysis in another organism", "d": ["The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904874", "l": "positive regulation of telomerase RNA localization to Cajal body", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990388", "l": "xylem-to-phloem iron transport", "d": ["The directed movement of iron ions into the phloem from the xylem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0010810", "l": "regulation of cell-substrate adhesion", "d": ["Any process that modulates the frequency, rate or extent of cell-substrate adhesion. 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This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0097283", "l": "keratinocyte apoptotic process", "d": ["Any apoptotic process in a keratinocyte. 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"identifiers": [{"i": "GO:1903680", "l": "acinar cell of sebaceous gland differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0016973", "l": "poly(A)+ mRNA export from nucleus", "d": ["The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032654", "l": "regulation of interleukin-11 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-11 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001134", "l": "methane biosynthetic process from carbon monoxide", "d": ["The chemical reactions and pathways resulting in the 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090728", "l": "negative regulation of brood size", "d": ["Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032939", "l": "positive regulation of translation in response to oxidative stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051140", "l": "regulation of NK T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of natural killer T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902088", "l": "plant-type cell wall loosening involved in abscission", "d": ["Any plant-type cell wall loosening that is involved in abscission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060765", "l": "regulation of androgen receptor signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046847", "l": "filopodium assembly", "d": ["The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048260", "l": "positive regulation of receptor-mediated endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904932", "l": "negative regulation of cartilage condensation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902966", "l": "positive regulation of protein localization to early endosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to early endosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062093", "l": "lysophagy", "d": ["The selective autophagy process in which a damaged lysosome is degraded by macroautophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061862", "l": "cellular response to differentiation-inducing factor 2", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021541", "l": "ammon gyrus development", "d": ["The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. 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This then fuses with the plasma membrane and forms the ciliary membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0046121", "l": "deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042137", "l": "sequestering of neurotransmitter", "d": ["The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.756196854933549", "identifiers": [{"i": "GO:0099500", "l": "vesicle fusion to plasma membrane", "d": ["Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990432", "l": "siRNA 3'-end processing", "d": ["The process of forming the mature 3' end of a siRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018272", "l": "protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine", "d": ["The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031622", "l": "positive regulation of fever generation", "d": ["Any process that activates or increases the frequency, rate, or extent of fever generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.439570404242417", "identifiers": [{"i": "GO:0007283", "l": "spermatogenesis", "d": ["The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021551", "l": "central nervous system morphogenesis", "d": ["The process in which the anatomical structure of the central nervous system is generated and organized. 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An example of this process is found in Caenorhabditis elegans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0030157", "l": "pancreatic juice secretion", "d": ["The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. 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The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.697307061953843", "identifiers": [{"i": "GO:0007010", "l": "cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0080168", "l": "abscisic acid transport", "d": ["The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000587", "l": "negative regulation of platelet-derived growth factor receptor-beta signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010842", "l": "retina layer formation", "d": ["The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. 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The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000169", "l": "regulation of peptidyl-cysteine S-nitrosylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:1901880", "l": "negative regulation of protein depolymerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0060872", "l": "semicircular canal development", "d": ["The progression of the semicircular canal from its initial formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010610", "l": "regulation of mRNA stability involved in response to stress", "d": ["Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035228", "l": "negative regulation of glutamate-cysteine ligase activity", "d": ["Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900364", "l": "negative regulation of mRNA polyadenylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0042448", "l": "progesterone metabolic process", "d": ["The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006526", "l": "arginine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000370", "l": "positive regulation of clathrin-dependent endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.049795477572943", "identifiers": [{"i": "GO:0051172", "l": "negative regulation of nitrogen compound metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002590", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099161", "l": "regulation of presynaptic dense core granule exocytosis", "d": ["Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0070950", "l": "regulation of neutrophil mediated killing of bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.097525820927416", "identifiers": [{"i": "GO:0048705", "l": "skeletal system morphogenesis", "d": ["The process in which the anatomical structures of the skeleton are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000637", "l": "positive regulation of miRNA-mediated gene silencing", "d": ["A process that activates or increases the frequency, rate or extent of gene silencing by a microRNA (miRNA)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070478", "l": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.153640326263854", "identifiers": [{"i": "GO:0071407", "l": "cellular response to organic cyclic compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0050963", "l": "detection of electrical stimulus involved in sensory perception", "d": ["The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902082", "l": "positive regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002485", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. 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The intron is excised as a linear piece (though it may subsequently circularize)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043318", "l": "negative regulation of cytotoxic T cell degranulation", "d": ["Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039688", "l": "viral double stranded DNA replication via reverse transcription", "d": ["A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070599", "l": "fungal-type cell wall (1->3)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0061140", "l": "lung secretory cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0002249", "l": "lymphocyte anergy", "d": ["Any process contributing to lymphocyte anergy, a state of functional inactivation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001699", "l": "acetylcholine-induced gastric acid secretion", "d": ["The regulated release of gastric acid by parietal cells in response to acetylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0062225", "l": "negative regulation of somatic muscle development", "d": ["Any process that decreases the rate, frequency or extent of somatic muscle development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905688", "l": "negative regulation of diacylglycerol kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018362", "l": "peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester", "d": ["The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015817", "l": "histidine transport", "d": ["The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090328", "l": "regulation of olfactory learning", "d": ["Any process that modulates the rate, frequency, or extent of olfactory learning. 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DIF-1 is a chlorinated alkylphenone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0099538", "l": "synaptic signaling via neuropeptide", "d": ["Cell-cell signaling to or from a synapse, mediated by a peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001193", "l": "maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II", "d": ["Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030950", "l": "establishment or maintenance of actin cytoskeleton polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.605953599968913", "identifiers": [{"i": "GO:0061138", "l": "morphogenesis of a branching epithelium", "d": ["The process in which the anatomical structures of a branched epithelium are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070671", "l": "response to interleukin-12", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905441", "l": "response to chondroitin 4'-sulfate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:1903900", "l": "regulation of viral life cycle", "d": ["Any process that modulates the frequency, rate or extent of viral life cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061469", "l": "regulation of type B pancreatic cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900296", "l": "positive regulation of heptasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of heptasaccharide transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0052703", "l": "cellular modified histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044817", "l": "hydrogen generation via biophotolysis", "d": ["The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. 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This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010760", "l": "negative regulation of macrophage chemotaxis", "d": ["Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0002763", "l": "positive regulation of myeloid leukocyte differentiation", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0030857", "l": "negative regulation of epithelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0070232", "l": "regulation of T cell apoptotic process", "d": ["Any process that modulates the occurrence or rate of T cell death by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0046928", "l": "regulation of neurotransmitter secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021813", "l": "cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration", "d": ["The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046937", "l": "phytochelatin metabolic process", "d": ["The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0009219", "l": "pyrimidine deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002816", "l": "regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045717", "l": "negative regulation of fatty acid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010045", "l": "response to nickel cation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905387", "l": "response to beta-carotene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0031629", "l": "synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0120033", "l": "negative regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.525080921078057", "identifiers": [{"i": "GO:0006900", "l": "vesicle budding from membrane", "d": ["The evagination of a membrane, resulting in formation of a vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.601382156057369", "identifiers": [{"i": "GO:0042158", "l": "lipoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0035935", "l": "androgen secretion", "d": ["The regulated release of an androgen into the circulatory system. 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An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0007460", "l": "R8 cell fate commitment", "d": ["The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901116", "l": "cephamycin C metabolic process", "d": ["The chemical reactions and pathways involving cephamycin C."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021636", "l": "trigeminal nerve morphogenesis", "d": ["The process in which the anatomical structure of the trigeminal nerve is generated and organized. 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The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0160077", "l": "lipid droplet fusion", "d": ["The process by which a single lipid droplet is created from the fusion of two or more lipid droplets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0007124", "l": "pseudohyphal growth", "d": ["The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.741169254015119", "identifiers": [{"i": "GO:0010562", "l": "positive regulation of phosphorus metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046984", "l": "regulation of hemoglobin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042220", "l": "response to cocaine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002023", "l": "reduction of food intake in response to dietary excess", "d": ["An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.553878612054035", "identifiers": [{"i": "GO:0044042", "l": "glucan metabolic process", "d": ["The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003191", "l": "coronary sinus valve formation", "d": ["The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. 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Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009264", "l": "deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902840", "l": "positive regulation of nuclear migration along microtubule", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010568", "l": "regulation of budding cell apical bud growth", "d": ["Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901840", "l": "negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.099579202379552", "identifiers": [{"i": "GO:0010948", "l": "negative regulation of cell cycle process", "d": ["Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001579", "l": "medium-chain fatty acid transport", "d": ["The directed movement of a medium-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050888", "l": "determination of stimulus location", "d": ["The determination of where on the body surface, within the body or in the environment a stimulus originates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905274", "l": "regulation of modification of postsynaptic actin cytoskeleton", "d": ["Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902192", "l": "2-methylbut-2-enoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048091", "l": "positive regulation of female pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140021", "l": "mitochondrial ADP transmembrane transport", "d": ["The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.683527111924249", "identifiers": [{"i": "GO:0061448", "l": "connective tissue development", "d": ["The progression of a connective tissue over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110141", "l": "L-glutamate import into mitochondrion", "d": ["The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900153", "l": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007458", "l": "progression of morphogenetic furrow involved in compound eye morphogenesis", "d": ["The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. 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"identifiers": [{"i": "GO:0008611", "l": "ether lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035739", "l": "CD4-positive, alpha-beta T cell proliferation", "d": ["The expansion of a CD4-positive, alpha-beta T cell population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990953", "l": "intramanchette transport", "d": ["The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904260", "l": "negative regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097026", "l": "dendritic cell dendrite assembly", "d": ["Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0022400", "l": "regulation of rhodopsin mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling."], "t": 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"identifiers": [{"i": "GO:0018315", "l": "molybdenum incorporation into molybdenum-molybdopterin complex", "d": ["The incorporation of molybdenum into a molybdenum-molybdopterin complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.198290882285249", "identifiers": [{"i": "GO:0006643", "l": "membrane lipid metabolic process", "d": ["The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0033206", "l": "meiotic cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0061097", "l": "regulation of protein tyrosine kinase activity", 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"identifiers": [{"i": "GO:0006522", "l": "alanine metabolic process", "d": ["The chemical reactions and pathways involving alanine, 2-aminopropanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007096", "l": "regulation of exit from mitosis", "d": ["Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0007077", "l": "mitotic nuclear membrane disassembly", "d": ["The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0009691", "l": "cytokinin biosynthetic process", "d": ["The chemical reactions and 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0098962", "l": "regulation of postsynaptic neurotransmitter receptor activity", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. 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This process occurs throughout the length of the stomach."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015824", "l": "proline transport", "d": ["The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046842", "l": "trisporic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trisporic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035366", "l": "negative regulation of thymine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "47.804776683340336", "identifiers": [{"i": "GO:0003013", "l": "circulatory system process", "d": ["A organ system process carried out by any of the organs or tissues of the circulatory system. 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This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010040", "l": "response to iron(II) ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.303055834858796", "identifiers": [{"i": "GO:0007601", "l": "visual perception", "d": ["The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. 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The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0050849", "l": "negative regulation of calcium-mediated signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042705", "l": "ocellus photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0003171", "l": "atrioventricular valve development", "d": ["The progression of the atrioventricular valve over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901706", "l": "mesenchymal cell differentiation involved in bone development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903911", "l": "positive regulation of receptor clustering", "d": ["Any process that activates or increases the frequency, rate or extent of receptor clustering."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021796", "l": "cerebral cortex regionalization", "d": ["The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106434", "l": "retinal isomerization", "d": ["The reactions involved in isomerization of all trans to all cis retnal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032646", "l": "regulation of hepatocyte growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006726", "l": "eye pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0048489", "l": "synaptic vesicle transport", "d": ["The directed movement of synaptic vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0106005", "l": "RNA 5'-cap (guanine-N7)-methylation", "d": ["The process whereby a guanine in 5-cap is methylated at the N7 position of guanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000088", "l": "negative regulation of mesonephric glomerulus development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0032606", "l": "type I interferon production", "d": ["The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 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Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016112", "l": "polyterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001410", "l": "chlamydospore formation", "d": ["The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. 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This may occur via transport across the plasma membrane or via endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051874", "l": "sphinganine-1-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060720", "l": "spongiotrophoblast cell proliferation", "d": ["The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042839", "l": "D-glucuronate metabolic process", "d": ["The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905050", "l": "positive regulation of metallopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of metallopeptidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000052", "l": "positive regulation of non-canonical Wnt signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070148", "l": "mitochondrial glutaminyl-tRNA aminoacylation", "d": ["The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0090023", "l": "positive regulation of neutrophil chemotaxis", "d": ["Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045037", "l": "protein import into chloroplast stroma", "d": ["The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. 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Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901188", "l": "negative regulation of ephrin receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901026", "l": "ripoptosome assembly involved in necroptotic process", "d": ["The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032723", "l": "positive regulation of connective tissue growth factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048930", "l": "glial cell migration in posterior lateral line nerve", "d": ["The movement of a glial cell along the axons in the posterior lateral line nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044313", "l": "protein K6-linked deubiquitination", "d": ["A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021709", "l": "cerebellar basket cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. 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A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0050855", "l": "regulation of B cell receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1902415", "l": "regulation of mRNA binding", "d": ["Any process that modulates the frequency, rate or extent of mRNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035696", "l": "monocyte extravasation", "d": ["The migration of a monocyte from the blood vessels into the surrounding tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0001569", "l": "branching involved in blood vessel morphogenesis", "d": ["The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002201", "l": "somatic diversification of DSCAM-based immune receptors", "d": ["The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900075", "l": "positive regulation of neuromuscular synaptic transmission", "d": ["Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019481", "l": "L-alanine catabolic process, by transamination", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110090", "l": "positive regulation of hippocampal neuron apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0099551", "l": "trans-synaptic signaling by neuropeptide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "39.600653529570934", "identifiers": [{"i": "GO:0023061", "l": "signal release", "d": ["The process in which a signal is secreted or discharged into the extracellular medium from a cellular source."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007412", "l": "axon target recognition", "d": ["The process in which an axon recognizes and binds to a set of cells with which it may form stable connections."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905344", "l": "prostaglandin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prostaglandin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071359", "l": "cellular response to dsRNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032340", "l": "positive regulation of inhibin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021690", "l": "cerebellar molecular layer maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. 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Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090315", "l": "negative regulation of protein targeting to membrane", "d": ["Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014873", "l": "response to muscle activity involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. 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An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904003", "l": "negative regulation of sebum secreting cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141034", "l": "symbiont-mediated perturbation of host actin cytoskeleton via inhibition of actin polymerization", "d": ["The process in which an organism effects a change that disrupts the host actin cytoskeleton by inhibiting host actin from polymerizing. 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Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0031049", "l": "programmed DNA elimination", "d": ["A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071000", "l": "response to magnetism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900943", "l": "positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006265", "l": "DNA topological change", "d": ["The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035750", "l": "protein localization to myelin sheath abaxonal region", "d": ["Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0010114", "l": "response to red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031366", "l": "N-terminal peptidyl-asparagine deamination", "d": ["The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002522", "l": "leukocyte migration involved in immune response", "d": ["The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060624", "l": "regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033030", "l": "negative regulation of neutrophil apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014038", "l": "regulation of Schwann cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045592", "l": "regulation of cumulus cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002278", "l": "eosinophil activation involved in immune response", "d": ["The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090141", "l": "positive regulation of mitochondrial fission", "d": ["Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905638", "l": "negative regulation of mitochondrial mRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902280", "l": "regulation of RNA helicase activity", "d": ["Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904850", "l": "negative regulation of establishment of protein localization to telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061362", "l": "negative regulation of maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001121", "l": "coenzyme gamma-F420-2 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007508", "l": "larval heart development", "d": ["The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009811", "l": "stilbene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046314", "l": "phosphocreatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009779", "l": "noncyclic photosynthetic phosphorylation", "d": ["A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035040", "l": "sperm nuclear envelope removal", "d": ["Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031916", "l": "regulation of synaptic metaplasticity", "d": ["A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1901020", "l": "negative regulation of calcium ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106215", "l": "negative regulation of vesicle fusion with Golgi apparatus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042549", "l": "photosystem II stabilization", "d": ["The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0075226", "l": "encysted zoospore germination", "d": ["The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070499", "l": "exosporium assembly", "d": ["A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021665", "l": "rhombomere 5 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006982", "l": "response to lipid hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071701", "l": "regulation of MAPK export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0040001", "l": "establishment of mitotic spindle localization", "d": ["The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903518", "l": "positive regulation of single strand break repair", "d": ["Any process that activates or increases the frequency, rate or extent of single strand break repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030592", "l": "DNA ADP-ribosylation", "d": ["The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051466", "l": "positive regulation of corticotropin-releasing hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120195", "l": "positive regulation of anther dehiscence", "d": ["Any process that activates or increases the frequency, rate or extent of anther dehiscence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090355", "l": "positive regulation of auxin metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.866383925293761", "identifiers": [{"i": "GO:0019236", "l": "response to pheromone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035219", "l": "prothoracic disc development", "d": ["Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061794", "l": "conidium development", "d": ["The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006175", "l": "dATP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048386", "l": "positive regulation of retinoic acid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902805", "l": "positive regulation of synaptic vesicle transport", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0006026", "l": "aminoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0007469", "l": "antennal development", "d": ["The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0044277", "l": "cell wall disassembly", "d": ["A process that results in the breakdown of the cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0015888", "l": "thiamine transport", "d": ["The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060372", "l": "regulation of atrial cardiac muscle cell membrane repolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900071", "l": "regulation of sulfite transport", "d": ["Any process that modulates the frequency, rate or extent of sulfite transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.739291131225258", "identifiers": [{"i": "GO:0033238", "l": "regulation of amine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0045604", "l": "regulation of epidermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of epidermal cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0021800", "l": "cerebral cortex tangential migration", "d": ["The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046599", "l": "regulation of centriole replication", "d": ["Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052091", "l": "modulation of nutrient release by host", "d": ["Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019668", "l": "anaerobic catabolism of pairs of amino acids", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010661", "l": "positive regulation of muscle cell apoptotic process", "d": ["Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.161717068681156", "identifiers": [{"i": "GO:0007034", "l": "vacuolar transport", "d": ["The directed movement of substances into, out of or within a vacuole."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009773", "l": "photosynthetic electron transport in photosystem I", "d": ["A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900161", "l": "regulation of phospholipid scramblase activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipid scramblase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002550", "l": "positive regulation of plasma kallikrein-kinin cascade", "d": ["Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035172", "l": "hemocyte proliferation", "d": ["The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0035844", "l": "cloaca development", "d": ["The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0075217", "l": "negative regulation of spore encystment on host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.750267668659092", "identifiers": [{"i": "GO:0009891", "l": "positive regulation of biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034488", "l": "basic amino acid transmembrane export from vacuole", "d": ["The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000230", "l": "negative regulation of pancreatic stellate cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019061", "l": "uncoating of virus", "d": ["The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060330", "l": "regulation of response to type II interferon", "d": ["Any process that modulates the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006782", "l": "protoporphyrinogen IX biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019351", "l": "dethiobiotin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120320", "l": "lateral pseudopodium retraction", "d": ["The myosin-based contraction and retraction of a lateral pseudopodium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002480", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007479", "l": "leg disc proximal/distal pattern formation", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046049", "l": "UMP metabolic process", "d": ["The chemical reactions and pathways involving UMP, uridine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002233", "l": "leukocyte chemotaxis involved in immune response", "d": ["The movement of an immune cell in response to an external stimulus a part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901382", "l": "regulation of chorionic trophoblast cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990592", "l": "protein K69-linked ufmylation", "d": ["A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0042417", "l": "dopamine metabolic process", "d": ["The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0006284", "l": "base-excision repair", "d": ["In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. 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A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003225", "l": "left ventricular trabecular myocardium morphogenesis", "d": ["The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0003214", "l": "cardiac left ventricle morphogenesis", "d": ["The process in which the left cardiac ventricle is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051086", "l": "chaperone mediated protein folding independent of cofactor", "d": ["The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002804", "l": "positive regulation of antifungal peptide production", "d": ["Any process that activates or increases the frequency, rate, or extent of antifungal peptide production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000550", "l": "negative regulation of B cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0010464", "l": "regulation of mesenchymal cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032690", "l": "negative regulation of interleukin-1 alpha production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0170037", "l": "export from the mitochondrion", "d": ["The directed movement of substances from the mitochondrion to the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.653457143972261", "identifiers": [{"i": "GO:0061014", "l": "positive regulation of mRNA catabolic process", "d": ["Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.315929082021214", "identifiers": [{"i": "GO:0048103", "l": "somatic stem cell division", "d": ["The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001552", "l": "ovarian follicle atresia", "d": ["A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904701", "l": "Wnt-Frizzled-LRP5/6 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072670", "l": "mitochondrial tRNA threonylcarbamoyladenosine modification", "d": ["The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070656", "l": "mechanoreceptor differentiation involved in mechanosensory epithelium regeneration", "d": ["Differentiation of new mechanoreceptors to replace those lost or destroyed by injury."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015966", "l": "diadenosine tetraphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031921", "l": "pyridoxal phosphate transport", "d": ["The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014818", "l": "skeletal muscle satellite cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0044342", "l": "type B pancreatic cell proliferation", "d": ["The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. 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During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.233168548413452", "identifiers": [{"i": "GO:0009892", "l": "negative regulation of metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003054", "l": "circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus", "d": ["The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035163", "l": "embryonic hemocyte differentiation", "d": ["The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. 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Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072084", "l": "specification of distal tubule identity", "d": ["The process in which the distal tubule of the kidney nephron acquires its identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002439", "l": "chronic inflammatory response to antigenic stimulus", "d": ["A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042205", "l": "chlorinated hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043157", "l": "response to cation stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0030653", "l": "beta-lactam antibiotic metabolic process", "d": ["The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901417", "l": "negative regulation of response to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.626384042261094", "identifiers": [{"i": "GO:0009112", "l": "nucleobase metabolic process", "d": ["The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070179", "l": "D-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075043", "l": "melanization of appressorium wall", "d": ["The process in which melanin is produced in the appressorium of the symbiont. 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Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060763", "l": "mammary duct terminal end bud growth", "d": ["The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.726079367374183", "identifiers": [{"i": "GO:0052008", "l": "symbiont-mediated disruption of host cellular anatomical entity", "d": ["The process in which an organism effects a change that impairs the structure or function of a host cellular anatomical entity. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904667", "l": "negative regulation of ubiquitin protein ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010398", "l": "xylogalacturonan metabolic process", "d": ["The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.910894291485924", "identifiers": [{"i": "GO:0009913", "l": "epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0018106", "l": "peptidyl-histidine phosphorylation", "d": ["The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032084", "l": "regulation of type I site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010804", "l": "negative regulation of tumor necrosis factor-mediated signaling pathway", "d": ["Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903860", "l": "negative regulation of dendrite extension", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031215", "l": "shell calcification", "d": ["The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021990", "l": "neural plate formation", "d": ["The formation of the flat, thickened layer of ectodermal cells known as the neural plate. 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Identity is considered to be the aggregate of characteristics by which a structure is recognized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090221", "l": "mitotic spindle-templated microtubule nucleation", "d": ["The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015868", "l": "purine ribonucleotide transport", "d": ["The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071378", "l": "cellular response to growth hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060542", "l": "regulation of strand invasion", "d": ["Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0036092", "l": "phosphatidylinositol-3-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901389", "l": "negative regulation of transforming growth factor beta activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990277", "l": "parasexual reproduction with cellular fusion", "d": ["A type of reproduction in which new individuals are produced from two individuals, with the fusion of two somatic cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.674339030385639", "identifiers": [{"i": "GO:0050804", "l": "modulation of chemical synaptic transmission", "d": ["Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009729", "l": "detection of brassinosteroid stimulus", "d": ["The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097155", "l": "fasciculation of sensory neuron axon", "d": ["The collection of sensory neuron axons into a bundle of rods, known as a fascicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901200", "l": "negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress", "d": ["Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034585", "l": "21U-RNA metabolic process", "d": ["The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.239663535624402", "identifiers": [{"i": "GO:0048736", "l": "appendage development", "d": ["The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905081", "l": "positive regulation of cerebellar neuron development", "d": ["Any process that activates or increases the frequency, rate or extent of cerebellar neuron development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090638", "l": "phosphatidylcholine biosynthesis from phosphatidylethanolamine", "d": ["The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000475", "l": "maturation of 2S rRNA", "d": ["Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033027", "l": "positive regulation of mast cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070309", "l": "lens fiber cell morphogenesis", "d": ["The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.58909006025462", "identifiers": [{"i": "GO:1903313", "l": "positive regulation of mRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060971", "l": "embryonic heart tube left/right pattern formation", "d": ["The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0030704", "l": "vitelline membrane formation", "d": ["Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034612", "l": "response to tumor necrosis factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905327", "l": "tracheoesophageal septum formation", "d": ["The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120174", "l": "stress-induced homeostatically regulated protein degradation pathway", "d": ["A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904881", "l": "cellular response to hydrogen sulfide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "27.012552032388335", "identifiers": [{"i": "GO:0032501", "l": "multicellular organismal process", "d": ["Any biological process, occurring at the level of a multicellular organism, pertinent to its function."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902428", "l": "negative regulation of water channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900088", "l": "regulation of inositol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of inositol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044205", "l": "'de novo' UMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0120253", "l": "hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000465", "l": "exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0075214", "l": "spore encystment", "d": ["The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061442", "l": "cardiac muscle cell fate determination", "d": ["The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099149", "l": "regulation of postsynaptic neurotransmitter receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031664", "l": "regulation of lipopolysaccharide-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042707", "l": "ocellus photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042482", "l": "positive regulation of odontogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051594", "l": "detection of glucose", "d": ["The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904731", "l": "positive regulation of intestinal lipid absorption", "d": ["Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990236", "l": "proteasome core complex import into nucleus", "d": ["The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:1903401", "l": "L-lysine transmembrane transport", "d": ["The directed movement of L-lysine across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.876091073600094", "identifiers": [{"i": "GO:0043903", "l": "regulation of biological process involved in symbiotic interaction", "d": ["Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903002", "l": "positive regulation of lipid transport across blood-brain barrier", "d": ["Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903786", "l": "regulation of glutathione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of glutathione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060785", "l": "regulation of apoptosis involved in tissue homeostasis", "d": ["Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.905944596964282", "identifiers": [{"i": "GO:0002521", "l": "leukocyte differentiation", "d": ["The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900665", "l": "negative regulation of emodin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019750", "l": "chloroplast localization", "d": ["Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903217", "l": "negative regulation of protein processing involved in protein targeting to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046335", "l": "ethanolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010722", "l": "regulation of ferrochelatase activity", "d": ["Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046411", "l": "2-keto-3-deoxygluconate transmembrane transport", "d": ["The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052160", "l": "perturbation of host systemic acquired resistance", "d": ["A process in which an organism effects a change that affects systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009765", "l": "photosynthesis, light harvesting", "d": ["Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050434", "l": "positive regulation of viral transcription", "d": ["Any process that activates or increases the frequency, rate or extent of viral transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052702", "l": "cellular modified histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003067", "l": "circadian regulation of systemic arterial blood pressure by hormone", "d": ["The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903886", "l": "positive regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071990", "l": "maintenance of protein location to spindle pole body", "d": ["Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904597", "l": "negative regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060416", "l": "response to growth hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031496", "l": "positive regulation of mating type switching", "d": ["Any process that activates or increases the frequency, rate or extent of mating type switching."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046192", "l": "anaerobic phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010072", "l": "primary shoot apical meristem specification", "d": ["The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046331", "l": "lateral inhibition", "d": ["Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051661", "l": "maintenance of centrosome location", "d": ["Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0002807", "l": "positive regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000994", "l": "regulation of mannan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of mannan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042149", "l": "cellular response to glucose starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071581", "l": "regulation of zinc ion transmembrane import", "d": ["Any process that modulates the frequency, rate or extent of zinc ion import."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150159", "l": "negative regulation of interleukin-34 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018412", "l": "protein O-glucuronidation", "d": ["The modification of a protein by glucuronidation on an amino acid oxygen atom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0006706", "l": "steroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900994", "l": "(-)-secologanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-secologanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0009111", "l": "vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016261", "l": "selenocysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010515", "l": "negative regulation of induction of conjugation with cellular fusion", "d": ["Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1990942", "l": "mitotic metaphase chromosome recapture", "d": ["A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001200", "l": "positive regulation of dendritic cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0051654", "l": "establishment of mitochondrion localization", "d": ["The directed movement of the mitochondrion to a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085015", "l": "dormancy maintenance of symbiont in host", "d": ["Any process in which a dormant state is maintained by the symbiont within the host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061275", "l": "mesonephric proximal tubule development", "d": ["The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. 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A cardiac chamber is an enclosed cavity within the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061280", "l": "epithelial cell migration involved in mesonephric proximal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018881", "l": "bromoxynil metabolic process", "d": ["The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904692", "l": "positive regulation of type B pancreatic cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006013", "l": "mannose metabolic process", "d": ["The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905011", "l": "transmembrane phosphate ion transport from cytosol to vacuole", "d": ["The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097328", "l": "response to carboplatin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904909", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002927", "l": "archaeosine-tRNA biosynthetic process", "d": ["The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060904", "l": "regulation of protein folding in endoplasmic reticulum", "d": ["Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0072127", "l": "renal capsule development", "d": ["The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990540", "l": "mitochondrial manganese ion transmembrane transport", "d": ["The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009257", "l": "10-formyltetrahydrofolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046551", "l": "retinal cone cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. 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they react against SP100 auto-antibodies (PML = promyelocytic leukemia)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905551", "l": "negative regulation of protein localization to endoplasmic reticulum", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0036394", "l": "amylase secretion", "d": ["The controlled release of amylase from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097314", "l": "apoptosome assembly", "d": ["The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002227", "l": "innate immune response in mucosa", "d": ["Any process of the innate immune response that takes place in the mucosal tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0072525", "l": "pyridine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032263", "l": "GMP salvage", "d": ["Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1903540", "l": "establishment of protein localization to postsynaptic membrane", "d": ["The directed movement of a protein to a specific location in a postsynaptic membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0001887", "l": "selenium compound metabolic process", "d": ["The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0099172", "l": "presynapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902923", "l": "poly(3-hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902179", "l": "verruculogen metabolic process", "d": ["The chemical reactions and pathways involving verruculogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000661", "l": "positive regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901867", "l": "ecgonine methyl ester metabolic process", "d": ["The chemical reactions and pathways involving ecgonine methyl ester."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.528207968973732", "identifiers": [{"i": "GO:0090596", "l": "sensory organ morphogenesis", "d": ["Morphogenesis of a sensory organ. 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Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905821", "l": "positive regulation of chromosome condensation", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome condensation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061722", "l": "sulphoglycolysis", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061262", "l": "mesonephric renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the mesonephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046494", "l": "rhizobactin 1021 metabolic process", "d": ["The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "44.965742902998585", "identifiers": [{"i": "GO:0048869", "l": "cellular developmental process", "d": ["A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0014010", "l": "Schwann cell proliferation", "d": ["The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. 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This process occurs in phages to protein themselves from bacterial restriction enzyme systems. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. 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Cell form and size are variable."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901813", "l": "astaxanthin metabolic process", "d": ["The chemical reactions and pathways involving astaxanthin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902168", "l": "response to catechin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001034", "l": "positive regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032277", "l": "negative regulation of gonadotropin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904106", "l": "protein localization to microvillus", "d": ["A process in which a protein is transported to, or maintained in, a location within a microvillus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0045108", "l": "regulation of intermediate filament polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901622", "l": "positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051628", "l": "positive regulation of epinephrine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071785", "l": "endoplasmic reticulum cisternal network maintenance", "d": ["The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. 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The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0002538", "l": "arachidonic acid metabolite production involved in inflammatory response", "d": ["The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.593242189043409", "identifiers": [{"i": "GO:0021782", "l": "glial cell development", "d": ["The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0006513", "l": "protein monoubiquitination", "d": ["Addition of a single ubiquitin group to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.994485457618666", "identifiers": [{"i": "GO:0007155", "l": "cell adhesion", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071473", "l": "cellular response to cation stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042377", "l": "vitamin K catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1904356", "l": "regulation of telomere maintenance via telomere lengthening", "d": ["Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042351", "l": "'de novo' GDP-L-fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990539", "l": "fructose import across plasma membrane", "d": ["The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043485", "l": "endosome to pigment granule transport", "d": ["The directed movement of substances from endosomes to pigment granules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0007340", "l": "acrosome reaction", "d": ["The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902250", "l": "regulation of erythrocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009071", "l": "serine family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002175", "l": "protein localization to paranode region of axon", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071975", "l": "cell swimming", "d": ["Cell motility that results in the smooth movement of a cell through a liquid medium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901062", "l": "guaiacyl lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900662", "l": "negative regulation of emericellamide A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0050427", "l": "3'-phosphoadenosine 5'-phosphosulfate metabolic process", "d": ["The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014735", "l": "regulation of muscle atrophy", "d": ["Any process that modulates the frequency, rate or extent of muscle atrophy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006647", "l": "phosphatidyl-N-monomethylethanolamine biosynthetic process", "d": ["The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902844", "l": "positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway", "d": ["A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000324", "l": "positive regulation of glucocorticoid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000186", "l": "negative regulation of phosphate transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061287", "l": "mesonephric capsule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. 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It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.569731477099452", "identifiers": [{"i": "GO:0007444", "l": "imaginal disc development", "d": ["The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071471", "l": "cellular response to non-ionic osmotic stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042468", "l": "klinokinesis", "d": ["The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018889", "l": "2-chloro-N-isopropylacetanilide metabolic process", "d": ["The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097503", "l": "sialylation", "d": ["The covalent attachment of sialic acid to a substrate molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904632", "l": "cellular response to glucoside", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140024", "l": "plus-end-directed endosome transport along mitotic spindle midzone microtubule", "d": ["The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018926", "l": "methanesulfonic acid metabolic process", "d": ["The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000468", "l": "generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902681", "l": "regulation of replication fork arrest at rDNA repeats", "d": ["Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071107", "l": "response to parathyroid hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019540", "l": "catechol-containing siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. 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Some GSI anchors have variants on this canonical linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905164", "l": "positive regulation of phagosome maturation", "d": ["Any process that activates or increases the frequency, rate or extent of phagosome maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010756", "l": "positive regulation of plasminogen activation", "d": ["Any process that increases the rate, frequency or extent of plasminogen activation. 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An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1902017", "l": "regulation of cilium assembly", "d": ["Any process that modulates the frequency, rate or extent of cilium assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001049", "l": "regulation of tendon cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of tendon cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050894", "l": "determination of affect", "d": ["Any process in which an emotional response is associated with a particular sensory stimulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.593242189043409", "identifiers": [{"i": "GO:0046530", "l": "photoreceptor cell differentiation", "d": ["The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. 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It can be derived from glucose by reduction of the aldehyde group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902206", "l": "negative regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902079", "l": "D-valine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-valine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071311", "l": "cellular response to acetate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.342419411848184", "identifiers": [{"i": "GO:0044058", "l": "regulation of digestive system process", "d": ["Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0072003", "l": "kidney rudiment formation", "d": ["The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. 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Examples of this process are found in Bacterial and Fungal species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0051985", "l": "negative regulation of chromosome segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.976681203957298", "identifiers": [{"i": "GO:0072697", "l": "protein localization to cell cortex", "d": ["A process in which a protein is transported to, or maintained in, the cell cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071809", "l": "regulation of fever generation by regulation of prostaglandin biosynthesis", "d": ["Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.224559434924572", "identifiers": [{"i": "GO:0015872", "l": "dopamine transport", "d": ["The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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May involve the formation of specialized cell junctions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904510", "l": "positive regulation of protein localization to basolateral plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051451", "l": "myoblast migration", "d": ["The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. 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Rhombomeres are numbered in anterior to posterior order."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034165", "l": "positive regulation of toll-like receptor 9 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.626384042261094", "identifiers": [{"i": "GO:0009134", "l": "nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042784", "l": "symbiont-mediated suppression of host complement activation", "d": ["A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007450", "l": "dorsal/ventral pattern formation, imaginal disc", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0055012", "l": "ventricular cardiac muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000261", "l": "negative regulation of blood coagulation, common pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019255", "l": "glucose 1-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0072033", "l": "renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. 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Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060532", "l": "bronchus cartilage development", "d": ["The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905615", "l": "positive regulation of developmental vegetative growth", "d": ["Any process that activates or increases the frequency, rate or extent of developmental vegetative growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045051", "l": "protein insertion into ER membrane by internal uncleaved signal-anchor sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018245", "l": "protein O-linked glycosylation via tyrosine", "d": ["The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0140500", "l": "regulation of reticulophagy", "d": ["Any process that modulates the frequency, rate or extent of reticulophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904199", "l": "positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015988", "l": "energy coupled proton transmembrane transport, against electrochemical gradient", "d": ["The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060628", "l": "regulation of ER to Golgi vesicle-mediated transport", "d": ["Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.947334934210822", "identifiers": [{"i": "GO:0030001", "l": "metal ion transport", "d": ["The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140898", "l": "CENP-A eviction from euchromatin", "d": ["A chromatin remodeling process in which CENP-A is removed from euchromatin regions to prevent neocentromere formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904801", "l": "positive regulation of neuron remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of neuron remodeling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070817", "l": "P-TEFb-cap methyltransferase complex localization", "d": ["Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035293", "l": "chitin-based larval cuticle pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043456", "l": "regulation of pentose-phosphate shunt", "d": ["Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048714", "l": "positive regulation of oligodendrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006741", "l": "NADP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902362", "l": "melanocyte apoptotic process", "d": ["Any apoptotic process in a melanocyte, the main structural component of the epidermis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000412", "l": "positive regulation of thymocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0032641", "l": "lymphotoxin A production", "d": ["The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0018945", "l": "organosilicon metabolic process", "d": ["The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0047497", "l": "mitochondrion transport along microtubule", "d": ["The directed movement of a mitochondrion along a microtubule, mediated by motor proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070502", "l": "capsule poly-gamma-glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905177", "l": "tracheary element differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070536", "l": "protein K63-linked deubiquitination", "d": ["A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009728", "l": "detection of gibberellic acid stimulus", "d": ["The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018028", "l": "peptidyl-lysine myristoylation", "d": ["The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048160", "l": "primary follicle stage", "d": ["The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900663", "l": "positive regulation of emericellamide A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030208", "l": "dermatan sulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019857", "l": "5-methylcytosine metabolic process", "d": ["The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035802", "l": "adrenal cortex formation", "d": ["The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903496", "l": "response to 11-deoxycorticosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905823", "l": "negative regulation of mitotic sister chromatid arm separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021660", "l": "rhombomere 3 formation", "d": ["The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080166", "l": "stomium development", "d": ["The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900884", "l": "regulation of tridecane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tridecane biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141115", "l": "symbiont-mediated suppression of host complement activation by inactivation of complement proteins", "d": ["A process by which a symbiont disrupts or prematurely activates host complement so that its microbial-destroying activities fail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046417", "l": "chorismate metabolic process", "d": ["The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001955", "l": "blood vessel maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904430", "l": "negative regulation of t-circle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003058", "l": "hormonal regulation of the force of heart contraction", "d": ["The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060697", "l": "positive regulation of phospholipid catabolic process", "d": ["Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000808", "l": "negative regulation of synaptic vesicle clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001107", "l": "negative regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043124", "l": "negative regulation of canonical NF-kappaB signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035853", "l": "chromosome passenger complex localization to spindle midzone", "d": ["A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060781", "l": "mesenchymal cell proliferation involved in prostate gland development", "d": ["The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002106", "l": "endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021591", "l": "ventricular system development", "d": ["The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0070266", "l": "necroptotic process", "d": ["A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034169", "l": "positive regulation of toll-like receptor 10 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0052542", "l": "defense response by callose deposition", "d": ["Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0010514", "l": "induction of conjugation with cellular fusion", "d": ["The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0019988", "l": "charged-tRNA amino acid modification", "d": ["The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019258", "l": "4-nitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:1904064", "l": "positive regulation of cation transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of cation transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032966", "l": "negative regulation of collagen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0009437", "l": "carnitine metabolic process", "d": ["The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902491", "l": "negative regulation of sperm capacitation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051914", "l": "positive regulation of synaptic plasticity by chemical substance", "d": ["The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.713478367176648", "identifiers": [{"i": "GO:0043086", "l": "negative regulation of catalytic activity", "d": ["Any process that stops or reduces the activity of an enzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046761", "l": "viral budding from plasma membrane", "d": ["A viral budding that starts with formation of a curvature in the host plasma membrane around which the virion particle assembles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904503", "l": "negative regulation of lipophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000936", "l": "regulation of cellotriose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellotriose catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.385242451594038", "identifiers": [{"i": "GO:0071692", "l": "protein localization to extracellular region", "d": ["Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009231", "l": "riboflavin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097318", "l": "invasive growth in response to abiotic stimulus", "d": ["The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035118", "l": "embryonic pectoral fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006682", "l": "galactosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1901662", "l": "quinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quinone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072740", "l": "cellular response to anisomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0140115", "l": "export across plasma membrane", "d": ["The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140899", "l": "plastid gene expression", "d": ["The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0052111", "l": "symbiont-mediated disruption of host anatomical structure", "d": ["The process in which an organism effects a change that impairs the structure or function of an anatomical structure of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048094", "l": "male pigmentation", "d": ["Establishment of a pattern of pigment in males."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002015", "l": "regulation of systemic arterial blood pressure by atrial baroreceptor feedback", "d": ["A process that controls blood pressure by sensing the amount of stretch occurring in the atria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904331", "l": "regulation of error-prone translesion synthesis", "d": ["Any process that modulates the frequency, rate or extent of error-prone translesion synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021958", "l": "gracilis tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000756", "l": "regulation of peptidyl-lysine acetylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035334", "l": "Notch receptor processing, ligand-independent", "d": ["The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:1901463", "l": "regulation of tetrapyrrole biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002620", "l": "negative regulation of non-professional antigen presenting cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0015816", "l": "glycine transport", "d": ["The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "15.147984789064841", "identifiers": [{"i": "GO:0008150", "l": "biological_process", "d": ["A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.", "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902962", "l": "regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990255", "l": "subsynaptic reticulum organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002188", "l": "translation reinitiation", "d": ["A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0015761", "l": "mannose transmembrane transport", "d": ["The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032463", "l": "negative regulation of protein homooligomerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061070", "l": "female urethra development", "d": ["The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903589", "l": "positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901303", "l": "negative regulation of cargo loading into COPII-coated vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061379", "l": "inferior colliculus development", "d": ["The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905490", "l": "negative regulation of sensory neuron axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0046887", "l": "positive regulation of hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002281", "l": "macrophage activation involved in immune response", "d": ["A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900759", "l": "positive regulation of D-amino-acid oxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900381", "l": "positive regulation of asperthecin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090167", "l": "Golgi distribution to daughter cells", "d": ["Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090051", "l": "negative regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003213", "l": "cardiac right atrium morphogenesis", "d": ["The process in which the right cardiac atrium is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0034508", "l": "centromere complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:2000191", "l": "regulation of fatty acid transport", "d": ["Any process that modulates the frequency, rate or extent of fatty acid transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009646", "l": "response to absence of light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.239663535624402", "identifiers": [{"i": "GO:0050777", "l": "negative regulation of immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0002659", "l": "negative regulation of peripheral tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0034412", "l": "ascospore wall beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904582", "l": "positive regulation of intracellular mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006583", "l": "melanin biosynthetic process from tyrosine", "d": ["The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019309", "l": "mannose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052837", "l": "thiazole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014885", "l": "detection of injury involved in regulation of muscle adaptation", "d": ["The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044211", "l": "CTP salvage", "d": ["Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071420", "l": "cellular response to histamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070857", "l": "regulation of bile acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902236", "l": "negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045339", "l": "farnesyl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006055", "l": "CMP-N-acetylneuraminate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0075016", "l": "appressorium formation", "d": ["The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905002", "l": "positive regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905826", "l": "negative regulation of selenocysteine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032495", "l": "response to muramyl dipeptide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904710", "l": "positive regulation of granulosa cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0106120", "l": "positive regulation of sterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0007032", "l": "endosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140455", "l": "cytoplasm protein quality control", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0150157", "l": "regulation of interleukin-34 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-34 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0061217", "l": "regulation of mesonephros development", "d": ["Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006860", "l": "extracellular amino acid transport", "d": ["The directed extracellular movement of amino acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034653", "l": "retinoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0043373", "l": "CD4-positive, alpha-beta T cell lineage commitment", "d": ["The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060331", "l": "negative regulation of response to type II interferon", "d": ["Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0055116", "l": "entry into reproductive diapause", "d": ["The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1903044", "l": "protein localization to membrane raft", "d": ["A process in which a protein is transported to, or maintained in, a location within a membrane raft."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990215", "l": "negative regulation by symbiont of host intracellular transport", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904395", "l": "positive regulation of skeletal muscle acetylcholine-gated channel clustering", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905676", "l": "positive regulation of adaptive immune memory response", "d": ["Any process that activates or increases the frequency, rate or extent of adaptive immune memory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0014842", "l": "regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007250", "l": "activation of NF-kappaB-inducing kinase activity", "d": ["The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0060180", "l": "female mating behavior", "d": ["The specific behavior of a female organism that is associated with reproduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070235", "l": "regulation of activation-induced cell death of T cells", "d": ["Any process that modulates the occurrence or rate of activation-induced cell death of T cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042673", "l": "regulation of retinal cone cell fate specification", "d": ["Any process that mediates the specification of a cell into a retinal cone cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901836", "l": "regulation of transcription of nucleolar large rRNA by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0090598", "l": "male anatomical structure morphogenesis", "d": ["The processes by which anatomical structures that are only present in the male organism are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905095", "l": "negative regulation of apolipoprotein A-I-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061120", "l": "regulation of positive chemotaxis to cAMP by DIF-1", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021677", "l": "rhombomere 8 formation", "d": ["The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1990755", "l": "mitotic spindle microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034409", "l": "ascospore wall (1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.774074961591239", "identifiers": [{"i": "GO:0008277", "l": "regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.577191797441309", "identifiers": [{"i": "GO:0034660", "l": "ncRNA metabolic process", "d": ["The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0080188", "l": "gene silencing by RNA-directed DNA methylation", "d": ["A small RNA-based gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. Transposable elements are silenced by this mechanism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0043542", "l": "endothelial cell migration", "d": ["The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061965", "l": "positive regulation of entry into reproductive diapause", "d": ["Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061888", "l": "regulation of astrocyte activation", "d": ["Any process that modulates the frequency, rate or extent of astrocyte activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009972", "l": "cytidine deamination", "d": ["The removal of amino group in the presence of water."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:1900674", "l": "olefin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of olefin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0030707", "l": "follicle cell of egg chamber development", "d": ["The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000512", "l": "negative regulation of granzyme A production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903745", "l": "negative regulation of nematode pharyngeal pumping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nematode pharyngeal pumping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021747", "l": "cochlear nucleus development", "d": ["The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.138718539170547", "identifiers": [{"i": "GO:0030029", "l": "actin filament-based process", "d": ["Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0141008", "l": "retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902891", "l": "negative regulation of root hair elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090617", "l": "mitochondrial mRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062162", "l": "positive regulation of pyocyanine biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "34.722841077207214", "identifiers": [{"i": "GO:0051234", "l": "establishment of localization", "d": ["Any process that localizes a substance or cellular component. 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An odorant is any substance capable of stimulating the sense of smell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0006538", "l": "glutamate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0090311", "l": "regulation of protein deacetylation", "d": ["Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904372", "l": "positive regulation of protein localization to actin cortical patch", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045458", "l": "recombination within rDNA repeats", "d": ["Genetic recombination within the DNA of the genes coding for ribosomal RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009659", "l": "leucoplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002570", "l": "somatic diversification of immunoglobulin genes by N region addition", "d": ["The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. 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This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035593", "l": "positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region", "d": ["Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019281", "l": "L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018419", "l": "protein catenane formation", "d": ["The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021658", "l": "rhombomere 3 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 3 is generated and organized. 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Rhombomeres are numbered in an anterior to posterior order."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051621", "l": "regulation of norepinephrine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071550", "l": "death-inducing signaling complex assembly", "d": ["A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0042435", "l": "indole-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061771", "l": "response to caloric restriction", "d": ["A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0018940", "l": "orcinol metabolic process", "d": ["The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0097581", "l": "lamellipodium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. 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Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.915726484813547", "identifiers": [{"i": "GO:0046835", "l": "carbohydrate phosphorylation", "d": ["The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904020", "l": "regulation of G protein-coupled receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150142", "l": "positive regulation of CD86 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.024411547311772", "identifiers": [{"i": "GO:0033273", "l": "response to vitamin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071468", "l": "cellular response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905261", "l": "regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903345", "l": "negative regulation of protein polyglycylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060038", "l": "cardiac muscle cell proliferation", "d": ["The expansion of a cardiac muscle cell population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072287", "l": "metanephric distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric distal tubule are generated and organized. 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This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900747", "l": "negative regulation of vascular endothelial growth factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141127", "l": "symbiont-mediated perturbation of host Rab signal transduction", "d": ["A process in which a symbiont alters a Rab protein family-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0060433", "l": "bronchus development", "d": ["The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903824", "l": "negative regulation of telomere single strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0021516", "l": "dorsal spinal cord development", "d": ["The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. 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An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904957", "l": "negative regulation of midbrain dopaminergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106398", "l": "negative regulation of R7 cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of R7 cell fate commitment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1903431", "l": "positive regulation of cell maturation", "d": ["Any process that activates or increases the frequency, rate or extent of cell maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001549", "l": "cumulus cell differentiation", "d": ["The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010890", "l": "positive regulation of sequestering of triglyceride", "d": ["Any process that increases the rate, frequency or extent of sequestering of triglyceride. 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An example of this process is found in nematode worms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0007132", "l": "meiotic metaphase I", "d": ["The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0110011", "l": "regulation of basement membrane organization", "d": ["Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901261", "l": "regulation of sorocarp spore cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009191", "l": "ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090548", "l": "response to nitrate starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034374", "l": "low-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036346", "l": "cellular response to L-cysteine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140330", "l": "xenobiotic detoxification by transmembrane export across the cell outer membrane", "d": ["A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0098749", "l": "cerebellar neuron development", "d": ["The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035185", "l": "preblastoderm mitotic cell cycle", "d": ["The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. 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The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039645", "l": "symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint", "d": ["A process in which a symbiont interferes with the normal execution of the host cell G1/S transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051634", "l": "inhibition of acetylcholine uptake", "d": ["Any process that prevents the activation of the directed movement of acetylcholine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019293", "l": "tyrosine biosynthetic process, by oxidation of phenylalanine", "d": ["The conversion of phenylalanine to tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0003318", "l": "cell migration to the midline involved in heart development", "d": ["The orderly movement of a cell toward the midline that contributes to the progression of the heart over time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048056", "l": "R3/R4 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150064", "l": "vertebrate eye-specific patterning", "d": ["Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033468", "l": "CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990068", "l": "seed dehydration", "d": ["The seed development process whose outcome is the drying of a maturing seed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045661", "l": "regulation of myoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of myoblast differentiation. 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Physiological hypertrophy is a normal process during development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.084918961990851", "identifiers": [{"i": "GO:0032505", "l": "reproduction of a single-celled organism", "d": ["The biological process in which new individuals are produced by one or two single-celled organisms. 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Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010025", "l": "wax biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:1903725", "l": "regulation of phospholipid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phospholipid metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902928", "l": "inulin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inulin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0048678", "l": "response to axon injury", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015941", "l": "pantothenate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007042", "l": "lysosomal lumen acidification", "d": ["Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.054967706738452", "identifiers": [{"i": "GO:0007613", "l": "memory", "d": ["The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0001952", "l": "regulation of cell-matrix adhesion", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009255", "l": "Entner-Doudoroff pathway through 6-phosphogluconate", "d": ["A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002852", "l": "regulation of T cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0080144", "l": "intracellular amino acid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018340", "l": "peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine", "d": ["The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903028", "l": "positive regulation of opsonization", "d": ["Any process that activates or increases the frequency, rate or extent of opsonization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902460", "l": "regulation of mesenchymal stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042412", "l": "taurine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.956219120605489", "identifiers": [{"i": "GO:0006813", "l": "potassium ion transport", "d": ["The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901414", "l": "negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075331", "l": "negative regulation of arbuscule formation for nutrient acquisition from host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901273", "l": "2-dehydro-3-deoxy-D-gluconic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106035", "l": "protein maturation by [4Fe-4S] cluster transfer", "d": ["The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010846", "l": "activation of reciprocal meiotic recombination", "d": ["Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061857", "l": "endoplasmic reticulum stress-induced pre-emptive quality control", "d": ["The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021744", "l": "dorsal motor nucleus of vagus nerve development", "d": ["The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043381", "l": "negative regulation of memory T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of memory T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070961", "l": "positive regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0021587", "l": "cerebellum morphogenesis", "d": ["The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106280", "l": "positive regulation of UDP-N-acetylglucosamine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901858", "l": "regulation of mitochondrial DNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010693", "l": "negative regulation of alkaline phosphatase activity", "d": ["Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010378", "l": "temperature compensation of the circadian clock", "d": ["The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032700", "l": "negative regulation of interleukin-17 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051872", "l": "sphingosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019652", "l": "lactate fermentation to propionate and acetate", "d": ["The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090119", "l": "vesicle-mediated cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902246", "l": "cis-abienol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cis-abienol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016557", "l": "peroxisome membrane biogenesis", "d": ["The process in which a peroxisome membrane is synthesized, aggregates, and bonds together."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051696", "l": "pointed-end actin filament uncapping", "d": ["The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0055023", "l": "positive regulation of cardiac muscle tissue growth", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0019693", "l": "ribose phosphate metabolic process", "d": ["The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904575", "l": "positive regulation of selenocysteine insertion sequence binding", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000431", "l": "regulation of transcription from RNA polymerase II promoter by galactose", "d": ["Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021965", "l": "spinal cord ventral commissure morphogenesis", "d": ["The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0097306", "l": "cellular response to alcohol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.221379778443747", "identifiers": [{"i": "GO:0001764", "l": "neuron migration", "d": ["The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009233", "l": "menaquinone metabolic process", "d": ["The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034442", "l": "regulation of lipoprotein oxidation", "d": ["Any process that modulates the frequency, rate or extent of lipoprotein oxidation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140982", "l": "detoxification of aluminum ion", "d": ["Any process that reduce or remove the toxicity of aluminum ions. These can include transport of the aluminum away from sensitive areas, sequesteration, or chemical modification to an inert form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0032594", "l": "protein transport within lipid bilayer", "d": ["The directed movement of a protein from one location to another within a lipid bilayer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "17.082571831283285", "identifiers": [{"i": "GO:0044237", "l": "cellular metabolic process", "d": ["The chemical reactions and pathways by which individual cells transform chemical substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044671", "l": "sorocarp spore cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0050830", "l": "defense response to Gram-positive bacterium", "d": ["Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045801", "l": "positive regulation of chitin-based cuticle tanning", "d": ["Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0006554", "l": "lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0036166", "l": "phenotypic switching", "d": ["A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. 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A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038041", "l": "cross-receptor inhibition within G protein-coupled receptor heterodimer", "d": ["Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043504", "l": "mitochondrial DNA repair", "d": ["The process of restoring mitochondrial DNA after damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018213", "l": "peptidyl-valine modification", "d": ["The modification of peptidyl-valine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0033338", "l": "medial fin development", "d": ["The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018027", "l": "peptidyl-lysine dimethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031508", "l": "pericentric heterochromatin formation", "d": ["The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072664", "l": "maintenance of protein location in peroxisome", "d": ["Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0051582", "l": "positive regulation of neurotransmitter uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016039", "l": "absorption of UV light", "d": ["The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140290", "l": "peptidyl-serine ADP-deribosylation", "d": ["The removal of ADP-ribose from ADP-ribosylserine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009998", "l": "negative regulation of retinal cone cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902039", "l": "negative regulation of seed dormancy process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0043545", "l": "molybdopterin cofactor metabolic process", "d": ["The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051142", "l": "positive regulation of NK T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0036227", "l": "mitotic G2 cell cycle arrest in response to glucose starvation", "d": ["The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070973", "l": "protein localization to endoplasmic reticulum exit site", "d": ["A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071281", "l": "cellular response to iron ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0015867", "l": "ATP transport", "d": ["The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902463", "l": "protein localization to cell leading edge", "d": ["A process in which a protein is transported to, or maintained in, a location within a cell leading edge."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:2000300", "l": "regulation of synaptic vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1901385", "l": "regulation of voltage-gated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010903", "l": "negative regulation of very-low-density lipoprotein particle remodeling", "d": ["Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904815", "l": "negative regulation of protein localization to chromosome, telomeric region", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904817", "l": "serous membrane development", "d": ["The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014838", "l": "myoblast fate specification involved in skeletal muscle regeneration", "d": ["The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.427753046175603", "identifiers": [{"i": "GO:0005996", "l": "monosaccharide metabolic process", "d": ["The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035481", "l": "positive regulation of Notch signaling pathway involved in heart induction", "d": ["Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150177", "l": "negative regulation of phosphatidylethanolamine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0021681", "l": "cerebellar granular layer development", "d": ["The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090349", "l": "negative regulation of cellular organohalogen metabolic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060689", "l": "cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905412", "l": "negative regulation of mitotic cohesin loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0098737", "l": "protein insertion into plasma membrane", "d": ["The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901799", "l": "negative regulation of proteasomal protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0110114", "l": "negative regulation of lipid transporter activity", "d": ["Any process that decreases the frequency, rate, or extent of lipid transporter activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902447", "l": "negative regulation of shade avoidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0003179", "l": "heart valve morphogenesis", "d": ["The process in which the structure of a heart valve is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060552", "l": "positive regulation of fructose 1,6-bisphosphate metabolic process", "d": ["Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018002", "l": "N-terminal peptidyl-glutamic acid acetylation", "d": ["The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071895", "l": "odontoblast differentiation", "d": ["The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035382", "l": "sterol transmembrane transport", "d": ["The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0045621", "l": "positive regulation of lymphocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0097091", "l": "synaptic vesicle clustering", "d": ["The process that results in grouping synaptic vesicles in presynaptic structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097037", "l": "heme export", "d": ["The directed movement of heme out of a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905190", "l": "negative regulation of 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in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046269", "l": "toluene-4-sulfonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046656", "l": "folic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0007030", "l": "Golgi organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009211", "l": "pyrimidine deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006613", "l": "cotranslational protein targeting to membrane", "d": ["The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0045104", "l": "intermediate filament cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010908", "l": "regulation of heparan sulfate proteoglycan biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0006279", "l": "premeiotic DNA replication", "d": ["The replication of DNA that precedes meiotic cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061518", "l": "microglial cell proliferation", "d": ["The expansion of a microglial cell population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900768", "l": "fonsecin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fonsecin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0000436", "l": "carbon catabolite activation of transcription from RNA polymerase II promoter", "d": ["Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0140133", "l": "symbiont-mediated suppression of host cytokine production", "d": ["A process by which a symbiont inhibits or disrupts the normal rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0072131", "l": "kidney mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080060", "l": "integument development", "d": ["The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902949", "l": "positive regulation of tau-protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045982", "l": "negative regulation of purine nucleobase metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000940", "l": "negative regulation of plant-type cell wall cellulose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902087", "l": "dimethylsulfoniopropionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0031126", "l": "sno(s)RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046968", "l": "peptide antigen transport", "d": ["The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0048898", "l": "anterior lateral line system development", "d": ["The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060233", "l": "oenocyte delamination", "d": ["The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0000916", "l": "actomyosin contractile ring contraction", "d": ["The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060345", "l": "spleen trabecula formation", "d": ["The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046293", "l": "formaldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160095", "l": "insect pharynx development", "d": ["The process whose specific outcome is the progression of insect pharynx over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0002720", "l": "positive regulation of cytokine production involved in immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055091", "l": "phospholipid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042932", "l": "chrysobactin transport", "d": ["The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0015995", "l": "chlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.796139606449842", "identifiers": [{"i": "GO:0006704", "l": "glucocorticoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075000", "l": "response to host osmotic environment", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060435", "l": "bronchiole development", "d": ["The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903922", "l": "negative regulation of protein processing in phagocytic vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0007443", "l": "Malpighian tubule morphogenesis", "d": ["The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. 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Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140201", "l": "urea import across plasma membrane", "d": ["The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032100", "l": "positive regulation of appetite", "d": ["Any process that increases appetite."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0044541", "l": "zymogen activation in another organism", "d": ["The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0044381", "l": "glucose import in response to insulin stimulus", "d": ["The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002148", "l": "hypochlorous acid metabolic process", "d": ["The chemical reactions and pathways involving hypochlorous acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905029", "l": "positive regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:1901992", "l": "positive regulation of mitotic cell cycle phase transition", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "50.945730862964297", "identifiers": [{"i": "GO:0070727", "l": "cellular macromolecule localization", "d": ["Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. 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Red light is electromagnetic radiation of wavelength of 580-700nm. 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The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019689", "l": "pyrimidine nucleoside interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1900371", "l": "regulation of purine nucleotide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045572", "l": "positive regulation of imaginal disc growth", "d": ["Any process that activates or increases the frequency, rate or extent of imaginal disc growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0061975", "l": "articular cartilage development", "d": ["The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:2000402", "l": "negative regulation of lymphocyte migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046772", "l": "viral budding from outer nuclear membrane", "d": ["The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903999", "l": "negative regulation of eating behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990688", "l": "Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903935", "l": "response to sodium arsenite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060177", "l": "regulation of angiotensin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001059", "l": "transcription by RNA polymerase IV", "d": ["The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048371", "l": "lateral mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902416", "l": "positive regulation of mRNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051137", "l": "negative regulation of NK T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006738", "l": "nicotinamide riboside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.669360725278217", "identifiers": [{"i": "GO:0051276", "l": "chromosome organization", "d": ["A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061854", "l": "positive regulation of neuroblast migration", "d": ["Any process that activates or increases the frequency, rate or extent of neuroblast migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "48.337709581533694", "identifiers": [{"i": "GO:0009628", "l": "response to abiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042077", "l": "protein phosphate-linked glycosylation via serine", "d": ["The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902126", "l": "(+)-pinoresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-pinoresinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032148", "l": "activation of protein kinase B activity", "d": ["Any process that initiates the activity of the inactive enzyme protein kinase B."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010949", "l": "negative regulation of intestinal phytosterol absorption", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039012", "l": "pronephric sinus development", "d": ["The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. 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Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002240", "l": "response to molecule of oomycetes origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900192", "l": "positive regulation of single-species biofilm formation", "d": ["Any process that activates or increases the frequency, rate or extent of single-species biofilm formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.014330232248525", "identifiers": [{"i": "GO:0042594", "l": "response to starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048309", "l": "endoplasmic reticulum inheritance", "d": ["The partitioning of endoplasmic reticulum between daughter cells at cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046219", "l": "indolalkylamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044694", "l": "symbiont genome entry into host cell via pore formation in plasma membrane", "d": ["Entry of a symbiont's genome into a host cell by a pore formed by the symbiont in the host cell. Examples of this process include injection by a non-enveloped virus of the viral genome into the host cytoplasm, usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.503937487960073", "identifiers": [{"i": "GO:0060627", "l": "regulation of vesicle-mediated transport", "d": ["Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017126", "l": "nucleologenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0030263", "l": "apoptotic chromosome condensation", "d": ["The compaction of chromatin during apoptosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0003422", "l": "growth plate cartilage morphogenesis", "d": ["The process in which the anatomical structures of growth plate cartilage are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010784", "l": "proboscis morphogenesis, clypeo-labral disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0002708", "l": "positive regulation of lymphocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070978", "l": "voltage-gated calcium channel complex assembly", "d": ["Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071978", "l": "bacterial-type flagellum-dependent swarming motility", "d": ["Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009708", "l": "benzyl isoquinoline alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140729", "l": "self-resistance to endogenously produced metabolite", "d": ["A process that reduces or removes the toxicity of an endogenously produced substance. 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Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000428", "l": "regulation of neutrophil aggregation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0016239", "l": "positive regulation of macroautophagy", "d": ["Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0140212", "l": "regulation of long-chain fatty acid import into cell", "d": ["Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030491", "l": "heteroduplex formation", "d": ["The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060022", "l": "hard palate development", "d": ["The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. 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The hard palate is the anterior portion of the palate consisting of bone and mucous membranes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071970", "l": "fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0018249", "l": "protein dehydration", "d": ["The removal of a water group from a protein amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009401", "l": "phosphoenolpyruvate-dependent sugar phosphotransferase system", "d": ["The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075504", "l": "macropinosomal membrane permeabilization involved in viral entry into host cell", "d": ["Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140821", "l": "UDP-beta-L-arabinofuranose import into Golgi lumen", "d": ["The directed movement of UDP-beta-L-arabinofuranose from the cytosol to the Golgi apparatus of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0098870", "l": "action potential propagation", "d": ["The propagation of an action potential along the plane of an excitable membrane. 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This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061368", "l": "behavioral response to formalin induced pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904882", "l": "regulation of telomerase catalytic core complex assembly", "d": ["Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0098961", "l": "dendritic transport of ribonucleoprotein complex", "d": ["The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031174", "l": "lifelong otolith mineralization", "d": ["The formation and growth of otoliths throughout the life of the organism. 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The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046722", "l": "lactic acid secretion", "d": ["The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901544", "l": "positive regulation of ent-pimara-8(14),15-diene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032732", "l": "positive regulation of interleukin-1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-1 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0072215", "l": "regulation of metanephros development", "d": ["Any process that modulates the rate, frequency or extent of metanephros development. 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The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042854", "l": "eugenol metabolic process", "d": ["The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032902", "l": "nerve growth factor production", "d": ["The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0036010", "l": "protein localization to endosome", "d": ["A process in which a protein is transported to, or maintained in, a location within an endosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.078697315966167", "identifiers": [{"i": "GO:1903829", "l": "positive regulation of protein localization", "d": ["Any process that activates or increases the frequency, rate or extent of a protein localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001145", "l": "negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046284", "l": "anthocyanin-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032492", "l": "detection of molecule of oomycetes origin", "d": ["The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070220", "l": "aerobic sulfur oxidation", "d": ["A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904051", "l": "regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0001974", "l": "blood vessel remodeling", "d": ["The reorganization or renovation of existing blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035115", "l": "embryonic forelimb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. 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The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905647", "l": "proline import across plasma membrane", "d": ["The directed movement of proline from outside of a cell into the cytoplasmic compartment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904055", "l": "negative regulation of cholangiocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903948", "l": "negative regulation of atrial cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019596", "l": "mandelate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. 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Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010782", "l": "proboscis morphogenesis, labial disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0044379", "l": "protein localization to actin cortical patch", "d": ["A process in which a protein is transported to, or maintained in, an actin cortical patch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905668", "l": "positive regulation of protein localization to endosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to endosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021803", "l": "extension of leading cell process to pial surface", "d": ["The extension of a long process to the pial surface as a cell leaves the ventricular zone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034116", "l": "positive regulation of heterotypic cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.401921375951204", "identifiers": [{"i": "GO:0019220", "l": "regulation of phosphate metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903749", "l": "positive regulation of establishment of protein localization to mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.915726484813547", "identifiers": [{"i": "GO:0022604", "l": "regulation of cell morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell morphogenesis. 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Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031162", "l": "sulfur incorporation into metallo-sulfur cluster", "d": ["The incorporation of exogenous sulfur into a metallo-sulfur cluster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010148", "l": "transpiration", "d": ["Release of water by the plant into the air as water vapor mainly through leaves."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021770", "l": "parahippocampal gyrus development", "d": ["The progression of the parahippocampal gyrus over time from its initial formation until its mature state. 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Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0072017", "l": "distal tubule development", "d": ["The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. 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This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046096", "l": "deoxyuridine metabolic process", "d": ["The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006620", "l": "post-translational protein targeting to endoplasmic reticulum membrane", "d": ["The targeting of proteins to a membrane that occurs after their translation. 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Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021936", "l": "regulation of cerebellar granule cell precursor proliferation", "d": ["The process that modulates the frequency, rate or extent of granule cell precursor proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010706", "l": "ganglioside biosynthetic process via lactosylceramide", "d": ["The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903773", "l": "negative regulation of viral budding via host ESCRT complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0090522", "l": "vesicle tethering involved in exocytosis", "d": ["The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044532", "l": "modulation of apoptotic process in another organism", "d": ["A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120142", "l": "positive regulation of ecdysone receptor-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048810", "l": "female analia morphogenesis", "d": ["The process in which the anatomical structures of the analia of the female are generated and organized. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042860", "l": "achromobactin metabolic process", "d": ["The chemical reactions and pathways involving achromobactin, a citrate siderophore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904948", "l": "midbrain dopaminergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905150", "l": "regulation of voltage-gated sodium channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033520", "l": "phytol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0003382", "l": "epithelial cell morphogenesis", "d": ["The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045754", "l": "positive regulation of acetate catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048623", "l": "seed germination on parent plant", "d": ["The process in which a seed germinates before being shed from the parent plant."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010373", "l": "negative regulation of gibberellin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0006074", "l": "(1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0051274", "l": "beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.488468354030026", "identifiers": [{"i": "GO:0015698", "l": "inorganic anion transport", "d": ["The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901089", "l": "acetate ester metabolic process involved in fermentation", "d": ["Any acetate ester metabolic process that is involved in fermentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007393", "l": "dorsal closure, leading edge cell fate determination", "d": ["The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0051326", "l": "telophase", "d": ["The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036261", "l": "7-methylguanosine cap hypermethylation", "d": ["Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. 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The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046676", "l": "negative regulation of insulin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042985", "l": "negative regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046140", "l": "corrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904303", "l": "positive regulation of maternal process involved in parturition", "d": ["Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.726079367374183", "identifiers": [{"i": "GO:0002718", "l": "regulation of cytokine production involved in immune response", "d": ["Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048873", "l": "homeostasis of number of cells within a tissue", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000970", "l": "regulation of detection of glucose", "d": ["Any process that modulates the frequency, rate or extent of detection of glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061128", "l": "positive regulation of chemotaxis to cAMP by DIF-2", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "47.782974553089169", "identifiers": [{"i": "GO:0006996", "l": "organelle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904388", "l": "negative regulation of ncRNA transcription associated with protein coding gene TSS/TES", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0018210", "l": "peptidyl-threonine modification", "d": ["The modification of peptidyl-threonine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036198", "l": "dTMP salvage", "d": ["Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140891", "l": "tRNA-derived regulatory ncRNA processing", "d": ["A process leading to the generation of a functional small regulatory non-coding RNA derived from a tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0033687", "l": "osteoblast proliferation", "d": ["The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. 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Hydroxyapatite crystals are then deposited into the matrix to form bone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904779", "l": "regulation of protein localization to centrosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to centrosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000791", "l": "negative regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0072283", "l": "metanephric renal vesicle morphogenesis", "d": ["The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. 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This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030885", "l": "regulation of myeloid dendritic cell activation", "d": ["Any process that modulates the frequency or rate of myeloid dendritic cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071801", "l": "regulation of podosome assembly", "d": ["Any process that modulates the frequency, rate or extent of podosome assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009196", "l": "pyrimidine deoxyribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.181437026927455", "identifiers": [{"i": "GO:0002262", "l": "myeloid cell homeostasis", "d": ["The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905569", "l": "negative regulation of ferrichrome biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0086068", "l": "Purkinje myocyte to ventricular cardiac muscle cell communication", "d": ["The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0001978", "l": "regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback", "d": ["The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0009084", "l": "glutamine family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.605953599968913", "identifiers": [{"i": "GO:0043069", "l": "negative regulation of programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000915", "l": "regulation of glucuronoxylan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0043478", "l": "pigment accumulation in response to UV light", "d": ["The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001007", "l": "negative regulation of cellulose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050652", "l": "dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process", "d": ["The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900421", "l": "positive regulation of cellular alcohol catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0007625", "l": "grooming behavior", "d": ["The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000210", "l": "positive regulation of anoikis", "d": ["Any process that activates or increases the frequency, rate or extent of anoikis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075196", "l": "adhesion of symbiont haustorium mother cell to host", "d": ["The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. 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This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903433", "l": "regulation of constitutive secretory pathway", "d": ["Any process that modulates the frequency, rate or extent of constitutive secretory pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902312", "l": "negative regulation of copper ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007396", "l": "suture of dorsal opening", "d": ["Closure of the dorsal hole. 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Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0050732", "l": "negative regulation of peptidyl-tyrosine phosphorylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045542", "l": "positive regulation of cholesterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072390", "l": "phenol metabolic process", "d": ["The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.245346374895831", "identifiers": [{"i": "GO:0000226", "l": "microtubule cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019500", "l": "cyanide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0045488", "l": "pectin metabolic process", "d": ["The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904248", "l": "regulation of age-related resistance", "d": ["Any process that modulates the extent of age-related resistance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002869", "l": "positive regulation of B cell deletion", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell deletion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1990845", "l": "adaptive thermogenesis", "d": ["The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0009187", "l": "cyclic nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033056", "l": "D-ornithine metabolic process", "d": ["The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060321", "l": "acceptance of pollen", "d": ["The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060125", "l": "negative regulation of growth hormone secretion", "d": ["Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075199", "l": "positive regulation of symbiont haustorium neck formation for entry into host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904373", "l": "response to kainic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009087", "l": "methionine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045968", "l": "negative regulation of juvenile hormone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070368", "l": "positive regulation of hepatocyte differentiation", "d": ["Any process that activates or increases the rate or extent of hepatocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098941", "l": "anterograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044830", "l": "modulation by host of viral RNA genome replication", "d": ["A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002464", "l": "peripheral tolerance induction to nonself antigen", "d": ["Tolerance induction to nonself antigens in the periphery."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0042167", "l": "heme catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006191", "l": "deoxyinosine salvage", "d": ["Any process that generates deoxyinosine from derivatives of it, without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072218", "l": "metanephric ascending thin limb development", "d": ["The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006056", "l": "mannoprotein metabolic process", "d": ["The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030713", "l": "follicle cell of egg chamber stalk formation", "d": ["Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. 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The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0005982", "l": "starch metabolic process", "d": ["The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052086", "l": "symbiont-mediated suppression of host B-cell mediated immune response", "d": ["A process by which a symbiont interferes with, inhibits or disrupts the normal execution of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0010411", "l": "xyloglucan metabolic process", "d": ["The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070666", "l": "regulation of mast cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mast cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.548370863794581", "identifiers": [{"i": "GO:0006869", "l": "lipid transport", "d": ["The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010286", "l": "heat acclimation", "d": ["Any process that increases heat tolerance of an organism in response to high temperatures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0034614", "l": "cellular response to reactive oxygen species", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0044560", "l": "envenomation resulting in modulation of ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0003281", "l": "ventricular septum development", "d": ["The progression of the ventricular septum over time from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071105", "l": "response to interleukin-11", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0043410", "l": "positive regulation of MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043326", "l": "chemotaxis to folate", "d": ["The directed movement of a motile cell or organism in response to the presence of folate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021618", "l": "hypoglossal nerve morphogenesis", "d": ["The process in which the anatomical structure of the hypoglossal nerve is generated and organized. 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The PIC engages RNA polymerase III on its DNA template strand and sparks polymerization of the first few RNA nucleotides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0003209", "l": "cardiac atrium morphogenesis", "d": ["The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0050959", "l": "echolocation", "d": ["Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032972", "l": "regulation of muscle filament sliding speed", "d": ["Any process that modulates the velocity of muscle filament sliding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.069524215212475", "identifiers": [{"i": "GO:0048878", "l": "chemical homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of a chemical."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070885", "l": "negative regulation of calcineurin-NFAT signaling cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002314", "l": "germinal center B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. 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GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035291", "l": "specification of segmental identity, intercalary segment", "d": ["The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1902603", "l": "carnitine transmembrane transport", "d": ["The directed movement of carnitine across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0035178", "l": "turning behavior", "d": ["Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090028", "l": "positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "d": ["Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:1903665", "l": "negative regulation of asexual reproduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097304", "l": "lipoprotein biosynthetic process via signal peptide cleavage", "d": ["The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0016116", "l": "carotenoid metabolic process", "d": ["The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015731", "l": "3-hydroxyphenyl propanoate transport", "d": ["The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019703", "l": "coenzyme A-peptidyl-cysteine covalent linking", "d": ["The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0006582", "l": "melanin metabolic process", "d": ["The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080167", "l": "response to karrikin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072100", "l": "specification of ureteric bud anterior/posterior symmetry", "d": ["The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039722", "l": "symbiont-mediated suppression of host toll-like receptor signaling pathway", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a toll-like receptor signaling pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902909", "l": "negative regulation of melanosome transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0051953", "l": "negative regulation of amine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0055015", "l": "ventricular cardiac muscle cell development", "d": ["The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007475", "l": "apposition of dorsal and ventral imaginal disc-derived wing surfaces", "d": ["The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0045806", "l": "negative regulation of endocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046084", "l": "adenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061979", "l": "femoral head articular cartilage development", "d": ["The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0009692", "l": "ethylene metabolic process", "d": ["The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006934", "l": "substrate-bound cell migration, adhesion receptor recycling", "d": ["The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0045745", "l": "positive regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904382", "l": "mannose trimming involved in glycoprotein ERAD pathway", "d": ["The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097681", "l": "double-strand break repair via alternative nonhomologous end joining", "d": ["An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048627", "l": "myoblast development", "d": ["The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033331", "l": "ent-kaurene metabolic process", "d": ["The chemical reactions and pathways involving ent-kaur-16-ene. 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This process is known to occur in some cyanobacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090208", "l": "positive regulation of triglyceride metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001989", "l": "positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903936", "l": "cellular response to sodium arsenite", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:1901875", "l": "positive regulation of post-translational protein modification", "d": ["Any process that activates or increases the frequency, rate or extent of post-translational protein modification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002623", "l": "negative regulation of B cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.836106170294514", "identifiers": [{"i": "GO:0051336", "l": "regulation of hydrolase activity", "d": ["Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042867", "l": "pyruvate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140922", "l": "positive regulation of thermomorphogenesis", "d": ["Any process that increases the rate, frequency or extent of thermomorphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0007483", "l": "genital disc morphogenesis", "d": ["The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060466", "l": "activation of meiosis involved in egg activation", "d": ["Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000625", "l": "regulation of miRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of miRNA catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0072025", "l": "distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035341", "l": "regulation of inosine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061485", "l": "memory T cell proliferation", "d": ["The expansion of a memory T cell population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0003229", "l": "ventricular cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0019359", "l": "nicotinamide nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0016479", "l": "negative regulation of transcription by RNA polymerase I", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901041", "l": "positive regulation of peptide antigen transport", "d": ["Any process that activates or increases the frequency, rate or extent of peptide antigen transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0051552", "l": "flavone metabolic process", "d": ["The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.490486312819655", "identifiers": [{"i": "GO:0000302", "l": "response to reactive oxygen species", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045487", "l": "gibberellin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gibberellin. 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This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904971", "l": "regulation of viral translation", "d": ["Any process that modulates the frequency, rate or extent of viral translation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.726079367374183", "identifiers": [{"i": "GO:0042471", "l": "ear morphogenesis", "d": ["The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010780", "l": "meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. 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It is made up of about 50 repeating units of a branched tetrasaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902209", "l": "negative regulation of bacterial-type flagellum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905398", "l": "activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any apoptotic process in an activated CD4-positive, alpha-beta T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060569", "l": "positive regulation of peptide hormone processing", "d": ["Any process that increases the rate, frequency or extent of peptide hormone processing. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0002646", "l": "regulation of central tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of central tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010686", "l": "tetracyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1904271", "l": "L-proline import across plasma membrane", "d": ["The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048033", "l": "heme O metabolic process", "d": ["The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0050765", "l": "negative regulation of phagocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000297", "l": "negative regulation of synapse maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1902601", "l": "silver ion transmembrane transport", "d": ["The directed movement of silver ion across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043330", "l": "response to exogenous dsRNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032335", "l": "regulation of activin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900965", "l": "regulation of methanophenazine metabolic process", "d": ["Any process 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"t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060771", "l": "phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990591", "l": "asparagine transmembrane import into vacuole", "d": ["The directed movement of asparagine into the vacuole across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032909", "l": "regulation of transforming growth factor beta2 production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0009448", "l": "gamma-aminobutyric acid metabolic process", "d": ["The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040026", "l": "positive regulation of vulval development", "d": ["Any process that activates or increases the frequency, rate or extent of development of the vulva. 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An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "17.229013549937189", "identifiers": [{"i": "GO:0044249", "l": "cellular biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120303", "l": "visually-mediated background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904370", "l": "regulation of protein localization to actin cortical patch", "d": ["Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903870", "l": "positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006491", "l": "N-glycan processing", "d": ["The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. 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The taste bud is a specialized area of the tongue that contains taste receptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0052319", "l": "regulation of phytoalexin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903499", "l": "regulation of mitotic actomyosin contractile ring assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030886", "l": "negative regulation of myeloid dendritic cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009052", "l": "pentose-phosphate shunt, non-oxidative branch", "d": ["The branch of the pentose-phosphate shunt which does not involve oxidation reactions. 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Catechol is a compound containing a pyrocatechol nucleus or substituent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032718", "l": "negative regulation of interleukin-9 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903848", "l": "negative regulation of aorta morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900954", "l": "negative regulation of 18-methylnonadec-1-ene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090680", "l": "viral release via disruption of host outer membrane", "d": ["The dissemination of mature viral particles from a host cell via the destabilization of the cell outer membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090339", "l": "negative regulation of formin-nucleated actin cable assembly", "d": ["Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. 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They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048814", "l": "regulation of dendrite morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of dendrite morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0051028", "l": "mRNA transport", "d": ["The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904924", "l": "negative regulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903457", "l": "lactate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901883", "l": "4-hydroxycoumarin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0019432", "l": "triglyceride biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901749", "l": "leukotriene D4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene D4."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052776", "l": "diacetylchitobiose catabolic process to glucosamine and acetate", "d": ["The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. 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This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048626", "l": "myoblast fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. 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The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002934", "l": "desmosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. 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It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048807", "l": "female genitalia morphogenesis", "d": ["The process in which the anatomical structures of female genitalia are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015790", "l": "UDP-xylose transmembrane transport", "d": ["The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031412", "l": "gas vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. 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"t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905799", "l": "regulation of intraciliary retrograde transport", "d": ["Any process that modulates the frequency, rate or extent of intraciliary retrograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034983", "l": "peptidyl-lysine deacetylation", "d": ["The removal of an acetyl group from an acetylated lysine residue in a peptide or protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000528", "l": "negative regulation of myeloid dendritic cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006601", "l": "creatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010585", "l": "glutamine secretion", "d": ["The controlled release of glutamine by a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007139", "l": "meiotic telophase II", "d": ["The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0071711", "l": "basement membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": 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"identifiers": [{"i": "GO:0030703", "l": "eggshell formation", "d": ["Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000221", "l": "negative regulation of pseudohyphal growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0099641", "l": "anterograde axonal protein transport", "d": ["The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904086", "l": "regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0051592", "l": "response to calcium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901186", "l": "positive regulation of ERBB signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0048280", "l": "vesicle 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075018", "l": "positive regulation of appressorium formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903645", "l": "negative regulation of chaperone-mediated protein folding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120158", "l": "positive regulation of collagen catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of collagen catabolism. 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Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.617478300466217", "identifiers": [{"i": "GO:0072009", "l": "nephron epithelium development", "d": ["The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070799", "l": "regulation of conidiophore stalk development", "d": ["Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. 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Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002388", "l": "immune response in Peyer's patch", "d": ["Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019343", "l": "cysteine biosynthetic process via cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046100", "l": "hypoxanthine metabolic process", "d": ["The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. 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Flowering is defined by the switch from the vegetative to the reproductive phase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042480", "l": "negative regulation of eye photoreceptor cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.374445519209623", "identifiers": [{"i": "GO:0015980", "l": "energy derivation by oxidation of organic compounds", "d": ["The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902786", "l": "response to dodecane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0002702", "l": "positive regulation of production of molecular mediator of immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021508", "l": "floor plate formation", "d": ["The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. 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Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033248", "l": "negative regulation of penicillin catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0042335", "l": "cuticle development", "d": ["The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030634", "l": "carbon fixation by acetyl-CoA pathway", "d": ["A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031581", "l": "hemidesmosome assembly", "d": ["Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. 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Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990580", "l": "regulation of cytoplasmic translational termination", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational termination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048838", "l": "release of seed from dormancy", "d": ["The process in which the dormant state is broken in a seed. 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A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902349", "l": "response to chloroquine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0032218", "l": "riboflavin transport", "d": ["The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0007214", "l": "gamma-aminobutyric acid signaling pathway", "d": ["The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010622", "l": "specification of ovule identity", "d": ["The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090006", "l": "regulation of linear element assembly", "d": ["Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904296", "l": "negative regulation of osmolarity-sensing cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.467472452979337", "identifiers": [{"i": "GO:0051707", "l": "response to other organism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900070", "l": "negative regulation of cellular hyperosmotic salinity response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904898", "l": "negative regulation of hepatic stellate cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0060419", "l": "heart growth", "d": ["The increase in size or mass of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904535", "l": "positive regulation of telomeric loop disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060018", "l": "astrocyte fate commitment", "d": ["The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051887", "l": "regulation of timing of exogen", "d": ["Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046724", "l": "oxalic acid secretion", "d": ["The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071225", "l": "cellular response to muramyl dipeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901165", "l": "positive regulation of trophoblast cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of trophoblast cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900032", "l": "regulation of trichome patterning", "d": ["Any process that modulates the frequency, rate or extent of trichome patterning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0016242", "l": "negative regulation of macroautophagy", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046947", "l": "hydroxylysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0018342", "l": "protein prenylation", "d": ["The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900890", "l": "regulation of pentadecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of pentadecane metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000059", "l": "negative regulation of ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0006369", "l": "termination of RNA polymerase II transcription", "d": ["A transcription termination process that completes the production of a primary RNA polymerase II transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035456", "l": "response to interferon-beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044387", "l": "negative regulation of protein kinase activity by regulation of protein phosphorylation", "d": ["The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0043154", "l": "negative regulation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021807", "l": "motogenic signaling initiating cell movement in cerebral cortex", "d": ["The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.186222083173888", "identifiers": [{"i": "GO:0048667", "l": "cell morphogenesis involved in neuron differentiation", "d": ["The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010510", "l": "regulation of acetyl-CoA biosynthetic process from pyruvate", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0019659", "l": "glucose catabolic process to lactate", "d": ["The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900764", "l": "emericellin metabolic process", "d": ["The chemical reactions and pathways involving emericellin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019087", "l": "transformation of host cell by virus", "d": ["A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051972", "l": "regulation of telomerase activity", "d": ["Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070810", "l": "positive regulation of Hulle cell development", "d": ["Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034112", "l": "positive regulation of homotypic cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021835", "l": "chemoattraction involved in embryonic olfactory bulb interneuron precursor migration", "d": ["The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0101030", "l": "tRNA-guanine transglycosylation", "d": ["The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097230", "l": "cell motility in response to potassium ion", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901339", "l": "regulation of store-operated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of store-operated calcium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021637", "l": "trigeminal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0022601", "l": "menstrual cycle phase", "d": ["The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0030474", "l": "spindle pole body duplication", "d": ["Construction of a new spindle pole body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:1901978", "l": "positive regulation of cell cycle checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048804", "l": "imaginal disc-derived female genitalia morphogenesis", "d": ["The process in which the anatomical structures of female genitalia are generated and organized from the genital disc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905138", "l": "positive regulation of viral DNA genome packaging via site-specific sequence recognition", "d": ["Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072482", "l": "response to mitotic cell cycle spindle orientation checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0048852", "l": "diencephalon morphogenesis", "d": ["The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0007164", "l": "establishment of tissue polarity", "d": ["Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.655379925225219", "identifiers": [{"i": "GO:0051250", "l": "negative regulation of lymphocyte activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904528", "l": "positive regulation of microtubule binding", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0000376", "l": "RNA splicing, via transesterification reactions with guanosine as nucleophile", "d": ["Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900127", "l": "positive regulation of hyaluronan biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035075", "l": "response to ecdysone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090473", "l": "lys-arg specific dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0060839", "l": "endothelial cell fate commitment", "d": ["The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003113", "l": "positive regulation of heart rate by neuronal norepinephrine", "d": ["The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0072172", "l": "mesonephric tubule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. 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This pathway is found in facultative anaerobes such as E. coli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036386", "l": "bacterial nucleoid packaging", "d": ["A process in which chromosomal DNA and associated proteins organize into a compact, orderly bacterial nucleoid. Often resulting in DNA supercoiling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035210", "l": "prepupal development", "d": ["The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:1902778", "l": "response to alkane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990832", "l": "slow axonal transport", "d": ["The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070863", "l": "positive regulation of protein exit from endoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072229", "l": "metanephric proximal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0051928", "l": "positive regulation of calcium ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0010518", "l": "positive regulation of phospholipase activity", "d": ["Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042791", "l": "5S class rRNA transcription by RNA polymerase III", "d": ["The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060622", "l": "regulation of ascospore wall beta-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0006672", "l": "ceramide metabolic process", "d": ["The chemical reactions and pathways involving ceramides, any N-acylated sphingoid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014031", "l": "mesenchymal cell development", "d": ["The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900503", "l": "regulation of cellulosome assembly", "d": ["Any process that modulates the frequency, rate or extent of cellulosome assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0002760", "l": "positive regulation of antimicrobial humoral response", "d": ["Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009971", "l": "anastral spindle assembly involved in male meiosis", "d": ["The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0006991", "l": "response to sterol depletion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. 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This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000700", "l": "positive regulation of cardiac muscle cell myoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019859", "l": "thymine metabolic process", "d": ["The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046276", "l": "methylgallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0060538", "l": "skeletal muscle organ development", "d": ["The progression of a skeletal muscle organ over time from its initial formation to its mature state. 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The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901660", "l": "calcium ion export", "d": ["The directed movement of calcium ion out of a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035200", "l": "leg disc anterior/posterior pattern formation", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034659", "l": "isopropylmalate transport", "d": ["The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140736", "l": "positive regulation of lovastatin biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of lovastin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002531", "l": "regulation of heart contraction involved in acute-phase response", "d": ["Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. 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Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905944", "l": "positive regulation of formation of growth cone in injured axon", "d": ["Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902906", "l": "proteasome storage granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150129", "l": "positive regulation of interleukin-33 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-33 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035377", "l": "transepithelial water transport", "d": ["The directed movement of water (H2O) from one side of an epithelium to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904236", "l": "negative regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.938801239267953", "identifiers": [{"i": "GO:0051235", "l": "maintenance of location", "d": ["Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010241", "l": "ent-kaurene oxidation to kaurenoic acid", "d": ["The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. 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An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070294", "l": "renal sodium ion absorption", "d": ["A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. 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An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.528207968973732", "identifiers": [{"i": "GO:0006835", "l": "dicarboxylic acid transport", "d": ["The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904524", "l": "negative regulation of DNA amplification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000756", "l": "response to pheromone regulating conjugation with mutual genetic exchange", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072223", "l": "metanephric glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. 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As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000766", "l": "negative regulation of cytoplasmic translation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0042982", "l": "amyloid precursor protein metabolic process", "d": ["The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0072577", "l": "endothelial cell apoptotic process", "d": ["Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140435", "l": "negative regulation of protein localization to meiotic spindle pole body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.432745995597372", "identifiers": [{"i": "GO:0072528", "l": "pyrimidine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905880", "l": "negative regulation of oogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061040", "l": "female gonad morphogenesis", "d": ["The process in which a female gonad is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014062", "l": "regulation of serotonin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of serotonin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070962", "l": "positive regulation of neutrophil mediated killing of bacterium", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014868", "l": "cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071037", "l": "nuclear polyadenylation-dependent snRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032208", "l": "negative regulation of telomere maintenance via recombination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0060317", "l": "cardiac epithelial to mesenchymal transition", "d": ["A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140884", "l": "symbiont-mediated suppression of host type II interferon-mediated signaling pathway", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010801", "l": "negative regulation of peptidyl-threonine phosphorylation", "d": ["Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. 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B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905899", "l": "regulation of smooth muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle tissue development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002149", "l": "hypochlorous acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hypochlorous acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901032", "l": "negative regulation of response to reactive oxygen species", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006256", "l": "UDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904715", "l": "negative regulation of chaperone-mediated autophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034334", "l": "adherens junction maintenance", "d": ["The maintenance of an adherens junction. 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They are important constituents of cell membranes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072750", "l": "cellular response to leptomycin B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901548", "l": "positive regulation of synaptic vesicle lumen acidification", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140572", "l": "vacuole fission", "d": ["The division of a vacuole within a cell to form two or more separate vacuoles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1990949", "l": "metaphase/anaphase transition of meiosis I", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051504", "l": "diterpene phytoalexin precursor biosynthetic process pathway", "d": ["A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.180713427975022", "identifiers": [{"i": "GO:0000022", "l": "mitotic spindle elongation", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902898", "l": "fatty acid methyl ester metabolic process", "d": ["The chemical reactions and pathways involving fatty acid methyl ester."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021663", "l": "rhombomere 4 formation", "d": ["The process that gives rise to rhombomere 4. 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Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902782", "l": "response to decane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.432745995597372", "identifiers": [{"i": "GO:0010469", "l": "regulation of signaling receptor activity", "d": ["Any process that modulates the frequency, rate or extent of a signaling receptor activity. 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A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033618", "l": "plasma membrane respiratory chain complex IV assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901457", "l": "regulation of response to acetate", "d": ["Any process that modulates the frequency, rate or extent of response to acetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019075", "l": "virus maturation", "d": ["The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070243", "l": "regulation of thymocyte apoptotic process", "d": ["Any process that modulates the occurrence or rate of thymocyte death by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0000082", "l": "G1/S transition of mitotic cell cycle", "d": ["The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0016094", "l": "polyprenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000237", "l": "leptotene", "d": ["The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.868222940810199", "identifiers": [{"i": "GO:0002027", "l": "regulation of heart rate", "d": ["Any process that modulates the frequency or rate of heart contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089705", "l": "protein localization to outer membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061220", "l": "mesonephric macula densa development", "d": ["The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0051353", "l": "positive regulation of oxidoreductase activity", "d": ["Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0031018", "l": "endocrine pancreas development", "d": ["The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. 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The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000592", "l": "regulation of metanephric DCT cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.475256590178944", "identifiers": [{"i": "GO:0046189", "l": "phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060708", "l": "spongiotrophoblast differentiation", "d": ["The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060673", "l": "cell-cell signaling involved in placenta development", "d": ["Any process that mediates the transfer of information from one cell to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048498", "l": "establishment of petal orientation", "d": ["The process that determines the orientation of petals with reference to the central axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070832", "l": "phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline", "d": ["The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061083", "l": "regulation of protein refolding", "d": ["Any process that regulates the rate, frequency, or extent of protein refolding. 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Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901878", "l": "positive regulation of calcium ion binding", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033088", "l": "negative regulation of immature T cell proliferation in thymus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009048", "l": "dosage compensation by inactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by heterochromatin formation leading to a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098964", "l": "anterograde dendritic transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070208", "l": "protein heterotrimerization", "d": ["The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052575", "l": "carbohydrate localization", "d": ["Any process in which a carbohydrate is transported to, or maintained in, a specific location. 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A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010125", "l": "mycothiol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904496", "l": "positive regulation of substance P secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034963", "l": "box C/D RNA processing", "d": ["Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006053", "l": "N-acetylmannosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035532", "l": "negative regulation of chemokine (C-C motif) ligand 6 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032678", "l": "regulation of interleukin-9 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-9 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060594", "l": "mammary gland specification", "d": ["The regionalization process in which the mammary line is specified. 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The tethering may facilitate exchange of metabolites between the organelles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032823", "l": "regulation of natural killer cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061969", "l": "maintenance of left sidedness", "d": ["The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903297", "l": "regulation of hypoxia-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048796", "l": "swim bladder maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. 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Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035041", "l": "sperm DNA decondensation", "d": ["Unwinding of the condensed nuclear chromatin of an inactive male pronucleus after fertilization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0003383", "l": "apical constriction", "d": ["The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035687", "l": "T-helper 1 cell extravasation", "d": ["The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. 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Large luteal cells develop from granulosa cells. 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Syncytia are normally derived from single cells that fuse or fail to complete cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.330956682939657", "identifiers": [{"i": "GO:2000146", "l": "negative regulation of cell motility", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010238", "l": "response to proline", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.513561067274054", "identifiers": [{"i": "GO:0061337", "l": "cardiac conduction", "d": ["Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070797", "l": "negative regulation of cleistothecium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060599", "l": "lateral sprouting involved in mammary gland duct morphogenesis", "d": ["The process in which a branch forms along the side of a mammary duct."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.915726484813547", "identifiers": [{"i": "GO:0009698", "l": "phenylpropanoid metabolic process", "d": ["The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0042710", "l": "biofilm formation", "d": ["A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1901523", "l": "icosanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of icosanoid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904570", "l": "negative regulation of selenocysteine incorporation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044331", "l": "cell-cell adhesion mediated by cadherin", "d": ["The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031108", "l": "holo-[acyl-carrier-protein] biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein]."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048207", "l": "vesicle targeting, rough ER to cis-Golgi", "d": ["The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000839", "l": "positive regulation of androstenedione secretion", "d": ["Any process that activates or increases the frequency, rate or extent of androstenedione secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010544", "l": "negative regulation of platelet activation", "d": ["Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901509", "l": "regulation of endothelial tube morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031364", "l": "N-terminal protein amino acid deamination, from side chain", "d": ["The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031425", "l": "chloroplast RNA processing", "d": ["The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903450", "l": "regulation of G1 to G0 transition", "d": ["Any process that modulates the frequency, rate or extent of G1 to G0 transition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002871", "l": "regulation of natural killer cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0062035", "l": "sensory perception of cold stimulus", "d": ["The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0097064", "l": "ncRNA export from nucleus", "d": ["The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097398", "l": "cellular response to interleukin-17", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003424", "l": "establishment of cell polarity involved in growth plate cartilage chondrocyte division", "d": ["The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060340", "l": "positive regulation of type I interferon-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070610", "l": "regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001193", "l": "positive regulation of gamma-delta T cell activation involved in 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"identifiers": [{"i": "GO:0003232", "l": "bulbus arteriosus development", "d": ["The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035353", "l": "nicotinamide mononucleotide transmembrane transport", "d": ["The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002856", "l": "negative regulation of natural killer cell mediated immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075322", "l": "regulation of oomycete sporangium development", "d": ["Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0007105", "l": "cytokinesis, division site positioning", "d": ["The process in which a contractile ring is positioned in a specific location. This process is critical for both for both symmetric and asymmetric cell divisions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010052", "l": "guard cell differentiation", "d": ["The process in which a guard mother cell acquires the specialized features of a guard cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902985", "l": "mitotic pre-replicative complex assembly", "d": ["Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036485", "l": "dorsolateral trunk neural crest cell migration", "d": ["The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0090287", "l": "regulation of cellular response to growth factor stimulus", "d": ["Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030417", "l": "nicotianamine metabolic process", "d": ["The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902422", "l": "hydrogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of H2 (dihydrogen)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071047", "l": "polyadenylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0072158", "l": "proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0008363", "l": "larval chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006334", "l": "nucleosome assembly", "d": ["The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900072", "l": "positive regulation of sulfite transport", "d": ["Any process that activates or increases the frequency, rate or extent of sulfite transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0120185", "l": "MBF transcription complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0045933", "l": "positive regulation of muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072275", "l": "metanephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the metanephric glomerulus are generated and organized. 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The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903914", "l": "negative regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120094", "l": "negative regulation of peptidyl-lysine crotonylation", "d": ["Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901453", "l": "positive regulation of response to benzene", "d": ["Any process that activates or increases the frequency, rate or extent of response to benzene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044844", "l": "meiotic interphase II", "d": ["The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000454", "l": "snoRNA guided rRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903889", "l": "negative regulation of plant epidermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0080117", "l": "secondary growth", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071610", "l": "chemokine (C-C motif) ligand 1 production", "d": ["The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0043111", "l": "replication fork arrest", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000317", "l": "negative regulation of T-helper 17 type immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0070127", "l": "tRNA aminoacylation for mitochondrial protein translation", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019431", "l": "acetyl-CoA biosynthetic process from ethanol", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0086054", "l": "bundle of His cell to Purkinje myocyte communication by electrical coupling", "d": ["The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061606", "l": "N-terminal protein amino acid propionylation", "d": ["The propionylation of the N-terminal amino acid of proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905959", "l": "positive regulation of cellular response to alcohol", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to alcohol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075248", "l": "regulation of aeciospore formation", "d": ["Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098507", "l": "polynucleotide 5' dephosphorylation", "d": ["The process of removing one or more phosphate groups from the 5' end of a polynucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072264", "l": "metanephric glomerular endothelium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.806983861220772", "identifiers": [{"i": "GO:0002698", "l": "negative regulation of immune effector process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0060512", "l": "prostate gland morphogenesis", "d": ["The process in which the anatomical structures of a prostate gland are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006685", "l": "sphingomyelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0044507", "l": "positive regulation of receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000208", "l": "positive regulation of ribosomal small subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002882", "l": "positive regulation of chronic inflammatory response to non-antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048168", "l": "regulation of neuronal synaptic plasticity", "d": ["A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. 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Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009992", "l": "intracellular water homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of water within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0060756", "l": "foraging behavior", "d": ["Behavior by which an organism locates food."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0015909", "l": "long-chain fatty acid transport", "d": ["The directed movement of a long-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.098012012402094", "identifiers": [{"i": "GO:0001819", "l": "positive regulation of cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of production of a cytokine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009234", "l": "menaquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097446", "l": "protein localization to eisosome filament", "d": ["A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.098012012402094", "identifiers": [{"i": "GO:0033260", "l": "nuclear DNA replication", "d": ["The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002158", "l": "osteoclast proliferation", "d": ["The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000658", "l": "positive regulation of apolipoprotein binding", "d": ["Any process that activates or increases the frequency, rate or extent of apolipoprotein binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.709179502404908", "identifiers": [{"i": "GO:0099124", "l": "axonal dopamine secretion", "d": ["The regulated release of dopamine from an axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0050763", "l": "depsipeptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0090033", "l": "positive regulation of filamentous growth", "d": ["Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000044", "l": "negative regulation of cardiac cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000162", "l": "negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0005981", "l": "regulation of glycogen catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051141", "l": "negative regulation of NK T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045571", "l": "negative regulation of imaginal disc growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904872", "l": "regulation of telomerase RNA localization to Cajal body", "d": ["Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903361", "l": "protein localization to basolateral plasma membrane", "d": ["Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0071806", "l": "protein transmembrane transport", "d": ["The process in which a protein is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902211", "l": "regulation of prolactin signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of prolactin signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035543", "l": "positive regulation of SNARE complex assembly", "d": ["Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000349", "l": "generation of catalytic spliceosome for first transesterification step", "d": ["Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003065", "l": "positive regulation of heart rate by epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061989", "l": "sperm karyosome formation", "d": ["The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0008272", "l": "sulfate transport", "d": ["The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021635", "l": "trigeminal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. 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The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090561", "l": "nuclear migration during mitotic telophase", "d": ["The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030813", "l": "positive regulation of nucleotide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048057", "l": "R3/R4 development", "d": ["The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071573", "l": "shelterin complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. 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The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0072310", "l": "glomerular epithelial cell development", "d": ["The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. 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Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.672771840408203", "identifiers": [{"i": "GO:1901570", "l": "fatty acid derivative biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fatty acid derivative."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0020027", "l": "hemoglobin metabolic process", "d": ["The chemical reactions and pathways involving hemoglobin, including its uptake and utilization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003063", "l": "negative regulation of heart rate by acetylcholine", "d": ["The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.540281582338167", "identifiers": [{"i": "GO:0071459", "l": "protein localization to chromosome, centromeric region", "d": ["Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140924", "l": "L-kynurenine transmembrane transport", "d": ["The directed movement of L-kynurenine across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902746", "l": "regulation of lens fiber cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lens fiber cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003120", "l": "regulation of vasoconstriction by circulating epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0036295", "l": "cellular response to increased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072120", "l": "pronephros maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061837", "l": "neuropeptide processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. 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Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901536", "l": "negative regulation of DNA demethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902993", "l": "positive regulation of amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0001835", "l": "blastocyst hatching", "d": ["The hatching of the cellular blastocyst from the zona pellucida."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048132", "l": "female germ-line stem cell asymmetric division", "d": ["The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000748", "l": "positive regulation of defecation rhythm", "d": ["Any process that activates or increases the frequency, rate or extent of defecation rhythm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072381", "l": "positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019417", "l": "sulfur oxidation", "d": ["The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0000463", "l": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990611", "l": "regulation of cytoplasmic translational initiation in response to stress", "d": ["Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0016240", "l": "autophagosome membrane docking", "d": ["The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. 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Class Ib here refers to non-classical class I molecules, such as those of the CD1 family."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.315929082021214", "identifiers": [{"i": "GO:0035930", "l": "corticosteroid hormone secretion", "d": ["The regulated release of any corticosteroid hormone into the circulatory system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048279", "l": "vesicle fusion with endoplasmic reticulum", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140877", "l": "mevastatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mevastatin , also known as compactin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA 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constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900337", "l": "negative regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.41723220320425", "identifiers": [{"i": "GO:1903828", "l": "negative regulation of protein localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046215", "l": "siderophore catabolic process", "d": ["The chemical reactions and pathways resulting in 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The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110080", "l": "positive regulation of placenta blood vessel development", "d": ["Any process that activates or increases the frequency, rate or extent of placenta blood vessel development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1903792", "l": "negative regulation of monoatomic anion transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anion transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905690", "l": "nucleus disassembly", "d": ["The disaggregation of a nucleus into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002933", "l": "lipid hydroxylation", "d": ["The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060891", "l": "limb granular cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048849", "l": "neurohypophysis formation", "d": ["The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021668", "l": "rhombomere 6 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.691787587221924", "identifiers": [{"i": "GO:0048880", "l": "sensory system development", "d": ["The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904848", "l": "negative regulation of cell chemotaxis to fibroblast growth factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0006298", "l": "mismatch repair", "d": ["A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. 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This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. 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Interferon lambda is the only member of the type III interferon found so far."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905091", "l": "positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0061082", "l": "myeloid leukocyte cytokine production", "d": ["Any process that contributes to cytokine production by a myeloid cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009454", "l": "aerotaxis", "d": ["The directed movement of a motile cell or organism in response to environmental oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0048593", "l": "camera-type eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized. 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Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072637", "l": "interleukin-32 production", "d": ["The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0160015", "l": "platelet rolling", "d": ["Transient adhesive interactions between platelets and endothelial cells lining blood vessels. Carbohydrates on circulating platelets bind selectins or other molecules on the vessel wall causing the platelets to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between surface molecules of platelets and endothelium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904900", "l": "negative regulation of myosin II filament organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035199", "l": "salt aversion", "d": ["The specific avoidance actions or reactions of an organism in response to the perception of salt."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:0097722", "l": "sperm motility", "d": ["Any process involved in the controlled movement of a sperm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.348348598122641", "identifiers": [{"i": "GO:0015721", "l": "bile acid and bile salt transport", "d": ["The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009199", "l": "ribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000860", "l": "positive regulation of aldosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of aldosterone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006049", "l": "UDP-N-acetylglucosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051793", "l": "medium-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a medium-chain fatty acid. 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A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903195", "l": "regulation of L-dopa biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905433", "l": "negative regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014057", "l": "positive regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015773", "l": "raffinose transport", "d": ["The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903384", "l": "negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080058", "l": "protein deglutathionylation", "d": ["The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032742", "l": "positive regulation of interleukin-19 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-19 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0045048", "l": "protein insertion into ER membrane", "d": ["The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. 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A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106062", "l": "positive regulation of exit from meiosis", "d": ["Any process that activates or increases the frequency, rate or extent of exit from meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0070050", "l": "neuron cellular homeostasis", "d": ["The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002006", "l": "vasoconstriction by vasopressin involved in systemic arterial blood pressure control", "d": ["The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902227", "l": "negative regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900717", "l": "negative regulation of violaceol II biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.653457143972261", "identifiers": [{"i": "GO:0006353", "l": "DNA-templated transcription termination", "d": ["The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036279", "l": "positive regulation of protein export from nucleus in response to glucose starvation", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051976", "l": "lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate", "d": ["The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044527", "l": "formation of peptidyl-cystine persulfide by sulphur transfer from H2S", "d": ["The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051459", "l": "regulation of corticotropin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021738", "l": "fastigial nucleus development", "d": ["The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000022", "l": "regulation of jasmonic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061744", "l": "motor behavior", "d": ["The specific neuromuscular movement of a single organism in response to external or internal stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902072", "l": "negative regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000842", "l": "positive regulation of dehydroepiandrosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:1902102", "l": "regulation of metaphase/anaphase transition of meiotic cell cycle", "d": ["Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002127", "l": "tRNA wobble base cytosine methylation", "d": ["The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0070633", "l": "transepithelial transport", "d": ["The directed movement of a substance from one side of an epithelium to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051456", "l": "attachment of meiotic spindle microtubules to meiosis II kinetochore", "d": ["The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099585", "l": "release of sequestered calcium ion into presynaptic cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0036446", "l": "myofibroblast differentiation", "d": ["The process in which an undifferentiated cell acquires the features of a myofibroblast cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0010051", "l": "xylem and phloem pattern formation", "d": ["The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014042", "l": "positive regulation of neuron maturation", "d": ["Any process that activates or increases the frequency, rate or extent of neuron maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010841", "l": "positive regulation of circadian sleep/wake cycle, wakefulness", "d": ["Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903248", "l": "regulation of citrulline biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of citrulline biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071678", "l": "olfactory bulb axon guidance", "d": ["The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904821", "l": "chloroplast disassembly", "d": ["The disaggregation of a chloroplast into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0035967", "l": "cellular response to topologically incorrect protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031642", "l": "negative regulation of myelination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032749", "l": "positive regulation of interleukin-25 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-25 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:1902480", "l": "protein localization to mitotic spindle", "d": ["A process in which a protein is transported to, or maintained in, a location within a mitotic spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904572", "l": "negative regulation of mRNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061931", "l": "positive regulation of erythrocyte enucleation", "d": ["Any process that increases the frequency, rate or extent of erythrocyte enucleation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097590", "l": "archaeal-type flagellum-dependent cell motility", "d": ["Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002087", "l": "regulation of respiratory gaseous exchange by nervous system process", "d": ["A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0046532", "l": "regulation of photoreceptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009828", "l": "plant-type cell wall loosening", "d": ["The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050788", "l": "sequestering of mercury", "d": ["The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042906", "l": "xanthine transport", "d": ["The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904612", "l": "response to 2,3,7,8-tetrachlorodibenzodioxine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904472", "l": "positive regulation of endothelin production", "d": ["Any process that activates or increases the frequency, rate or extent of endothelin production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106218", "l": "galactosaminogalactan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0051238", "l": "sequestering of metal ion", "d": ["The process of binding or confining metal ions such that they are separated from other components of a biological system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051166", "l": "2,5-dihydroxypyridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0042196", "l": "chlorinated hydrocarbon metabolic process", "d": ["The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035973", "l": "aggrephagy", "d": ["The selective degradation of protein aggregates by macroautophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046048", "l": "UDP metabolic process", "d": ["The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045775", "l": "positive regulation of beta 2 integrin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904783", "l": "positive regulation of NMDA glutamate receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902618", "l": "cellular response to fluoride", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902972", "l": "premeiotic DNA replication DNA ligation", "d": ["Any DNA ligation involved in meiotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034118", "l": "regulation of erythrocyte aggregation", "d": ["Any process that modulates the frequency, rate, or extent of erythrocyte aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006316", "l": "movement of group I intron", "d": ["Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0000730", "l": "DNA recombinase assembly", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010912", "l": "positive regulation of isomerase activity", "d": ["Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048768", "l": "root hair cell tip growth", "d": ["Localized growth of a plant root hair tip by extension of the cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090346", "l": "cellular organofluorine metabolic process", "d": ["The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140208", "l": "apoptotic process in response to mitochondrial fragmentation", "d": ["Any apoptotic process that occurs as a result of mitochondrial fragmentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0106091", "l": "glial cell projection elongation", "d": ["The process of creating an elongation or projection from a glial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003429", "l": "growth plate cartilage chondrocyte morphogenesis", "d": ["The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045317", "l": "equator specification", "d": ["The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060238", "l": "regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0050675", "l": "regulation of urothelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of urothelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0003407", "l": "neural retina development", "d": ["The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903187", "l": "negative regulation of vitellogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002498", "l": "proteolysis within endoplasmic reticulum associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002556", "l": "serotonin secretion by basophil", "d": ["The regulated release of serotonin by a basophil or group of basophils."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.063369062700268", "identifiers": [{"i": "GO:0071824", "l": "protein-DNA complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021831", "l": "embryonic olfactory bulb interneuron precursor migration", "d": ["The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.330956682939657", "identifiers": [{"i": "GO:0043467", "l": "regulation of generation of precursor metabolites and energy", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:1905359", "l": "protein localization to meiotic spindle", "d": ["A process in which a protein is transported to, or maintained in, a location within a meiotic spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032827", "l": "negative regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001304", "l": "lipoxin B4 metabolic process", "d": ["The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.921857375477728", "identifiers": [{"i": "GO:0098801", "l": "regulation of renal system process", "d": ["Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048887", "l": "cupula development", "d": ["The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901249", "l": "regulation of lung goblet cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lung goblet cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:1904478", "l": "regulation of intestinal absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal absorption."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090517", "l": "L-lysine transmembrane import into vacuole", "d": ["The directed movement of L-lysine into the vacuole across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0062089", "l": "regulation of taurine biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of taurine biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045993", "l": "negative regulation of translational initiation by iron", "d": ["Any process involving iron that stops, prevents or reduces the rate of translational initiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901209", "l": "positive regulation of heart looping", "d": ["Any process that activates or increases the frequency, rate or extent of heart looping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903595", "l": "positive regulation of histamine secretion by mast cell", "d": ["Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0061709", "l": "reticulophagy", "d": ["The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901516", "l": "aspyridone A metabolic process", "d": ["The chemical reactions and pathways involving aspyridone A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032981", "l": "mitochondrial respiratory chain complex I assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900698", "l": "regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007365", "l": "periodic partitioning", "d": ["The regionalization process that divides the spatial regions of an embryo into serially repeated regions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:2000401", "l": "regulation of lymphocyte migration", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0021565", "l": "accessory nerve development", "d": ["The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033071", "l": "vancomycin metabolic process", "d": ["The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070983", "l": "dendrite guidance", "d": ["The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900001", "l": "negative regulation of anthocyanin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901462", "l": "positive regulation of response to formic acid", "d": ["Any process that activates or increases the frequency, rate or extent of response to formic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140505", "l": "regulation of microlipophagy", "d": ["Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060118", "l": "vestibular receptor cell development", "d": ["The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. 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Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051617", "l": "negative regulation of histamine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033492", "l": "esculetin metabolic process", "d": ["The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032754", "l": "positive regulation of interleukin-5 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-5 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034120", "l": "positive regulation of erythrocyte aggregation", "d": ["Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051394", "l": "regulation of nerve growth factor receptor activity", "d": ["Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070429", "l": "negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:2000924", "l": "regulation of cellodextrin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellodextrin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905837", "l": "cellular response to triterpenoid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010481", "l": "epidermal cell division", "d": ["Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035776", "l": "pronephric proximal tubule development", "d": ["The progression of the pronephric proximal tubule over time, from its formation to the mature structure. 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The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904685", "l": "positive regulation of metalloendopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044559", "l": "envenomation resulting in modulation of voltage-gated potassium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900124", "l": "negative regulation of nodal receptor complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046311", "l": "prenylcysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044577", "l": "xylose catabolic process to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021946", "l": "deep nuclear neuron cell migration", "d": ["The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010085", "l": "polarity specification of proximal/distal axis", "d": ["Any process resulting in the establishment of polarity along the proximal/distal axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034510", "l": "centromere separation", "d": ["The cell cycle process in which centromeres are physically detached from each other during chromosome separation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035817", "l": "renal sodium ion absorption involved in negative regulation of renal sodium excretion", "d": ["Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061332", "l": "Malpighian tubule bud morphogenesis", "d": ["The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0097639", "l": "L-lysine import across plasma membrane", "d": ["The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009997", "l": "negative regulation of cardioblast cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. 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Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904604", "l": "negative regulation of advanced glycation end-product receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.683039265630129", "identifiers": [{"i": "GO:0046632", "l": "alpha-beta T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. 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A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000964", "l": "negative regulation of cellooligosaccharide catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0001109", "l": "promoter clearance during DNA-templated transcription", "d": ["Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. 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The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002607", "l": "regulation of myeloid dendritic cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905087", "l": "positive regulation of bioluminescence", "d": ["Any process that activates or increases the frequency, rate or extent of bioluminescence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045938", "l": "positive regulation of circadian sleep/wake cycle, sleep", "d": ["Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0009061", "l": "anaerobic respiration", "d": ["The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900152", "l": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045640", "l": "regulation of basophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of basophil differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042966", "l": "biotin carboxyl carrier protein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0090672", "l": "telomerase RNA localization", "d": ["Any process in which telomerase RNA is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0051328", "l": "meiotic interphase", "d": ["The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. 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Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019376", "l": "galactolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.410865998300608", "identifiers": [{"i": "GO:0141060", "l": "disruption of anatomical structure in another organism", "d": ["The disruption of an anatomical structure of another organism, leading to damage or temporary subversion of that structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002657", "l": "positive regulation of tolerance induction to nonself antigen", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905141", "l": "negative regulation of apical ectodermal ridge formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904980", "l": "positive regulation of endosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of endosome organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060040", "l": "retinal bipolar neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902429", "l": "positive regulation of water channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of water channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902318", "l": "synthesis of RNA primer involved in nuclear cell cycle DNA replication", "d": ["Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061363", "l": "negative regulation of progesterone biosynthesis involved in luteolysis", "d": ["Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032664", "l": "regulation of interleukin-20 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-20 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061169", "l": "positive regulation of hair placode formation", "d": ["Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0051581", "l": "negative regulation of neurotransmitter uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075195", "l": "negative regulation of haustorium mother cell formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033543", "l": "fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0071489", "l": "cellular response to red or far red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016560", "l": "protein import into peroxisome matrix, docking", "d": ["The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901996", "l": "regulation of indoleacetic acid biosynthetic process via tryptophan", "d": ["Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019594", "l": "mannitol metabolic process", "d": ["The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034994", "l": "microtubule organizing center attachment site organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071206", "l": "establishment of protein localization to juxtaparanode region of axon", "d": ["The directed movement of a protein to the juxtaparanode region of an axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905706", "l": "regulation of mitochondrial ATP synthesis coupled proton transport", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007629", "l": "flight behavior", "d": ["The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0046323", "l": "glucose import", "d": ["The directed movement of the hexose monosaccharide glucose into a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0006584", "l": "catecholamine metabolic process", "d": ["The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046431", "l": "(R)-4-hydroxymandelate metabolic process", "d": ["The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0042573", "l": "retinoic acid metabolic process", "d": ["The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0017000", "l": "antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014865", "l": "detection of activity", "d": ["The series of events in which an activity stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0042688", "l": "crystal cell differentiation", "d": ["The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048922", "l": "posterior lateral line neuromast deposition", "d": ["The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0035966", "l": "response to topologically incorrect protein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007536", "l": "activation of recombination (HML)", "d": ["The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904202", "l": "negative regulation of iodide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900073", "l": "regulation of neuromuscular synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902893", "l": "regulation of miRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of microRNA (miRNA) gene transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019498", "l": "n-octane oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904016", "l": "response to Thyroglobulin triiodothyronine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903701", "l": "substantia propria of cornea development", "d": ["The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0000038", "l": "very long-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0002427", "l": "mucosal tolerance induction", "d": ["Tolerance induction taking place in the mucosal tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051896", "l": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1902829", "l": "regulation of spinal cord association neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046226", "l": "coumarin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007130", "l": "synaptonemal complex assembly", "d": ["The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048756", "l": "sieve cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060646", "l": "internal mammary gland bud epithelial cell differentiation", "d": ["The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900612", "l": "F-9775B metabolic process", "d": ["The chemical reactions and pathways involving F-9775B."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903748", "l": "negative regulation of establishment of protein localization to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014710", "l": "negative regulation of somitomeric trunk muscle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0106012", "l": "positive regulation of protein localization to medial cortex", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0005997", "l": "xylulose metabolic process", "d": ["The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080151", "l": "positive regulation of salicylic acid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal 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Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006728", "l": "pteridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0010984", "l": "regulation of lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. 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SA node cells are pacemaker cells that are found in the sinoatrial node."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0097374", "l": "sensory neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003039", "l": "detection of reduced oxygen by carotid body chemoreceptor signaling", "d": ["The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001697", "l": "histamine-induced gastric acid secretion", "d": ["The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048324", "l": "regulation of axial mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099176", "l": "regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0099088", "l": "axonal transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in axons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001095", "l": "mannotriose transport", "d": ["The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000486", "l": "negative regulation of glutamine transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0030581", "l": "symbiont intracellular protein transport in host", "d": ["The directed movement of a symbiont's proteins within a cell of the host organism. 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Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000554", "l": "regulation of T-helper 1 cell cytokine production", "d": ["Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003249", "l": "cell proliferation involved in heart valve morphogenesis", "d": ["The multiplication or reproduction of cells that contributes to the shaping of a heart valve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046679", "l": "response to streptomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035855", "l": "megakaryocyte development", "d": ["The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900552", "l": "asperfuranone metabolic process", "d": ["The chemical reactions and pathways involving asperfuranone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036022", "l": "limb joint morphogenesis", "d": ["The process in which the anatomical structures of a limb joint are generated and organized. 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Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905909", "l": "regulation of dauer entry", "d": ["Any process that modulates the frequency, rate or extent of dauer entry."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0046390", "l": "ribose phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.918007390795673", "identifiers": [{"i": "GO:0045184", "l": "establishment of protein localization", "d": ["The directed movement of a protein to a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019278", "l": "UDP-N-acetylgalactosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106298", "l": "13-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.255037492017777", "identifiers": [{"i": "GO:0006520", "l": "amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140384", "l": "metacyclogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.249098858391747", "identifiers": [{"i": "GO:0044782", "l": "cilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019277", "l": "UDP-N-acetylgalactosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901822", "l": "delta-carotene metabolic process", "d": ["The chemical reactions and pathways involving delta-carotene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904240", "l": "negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.774074961591239", "identifiers": [{"i": "GO:0051341", "l": "regulation of oxidoreductase activity", "d": ["Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090206", "l": "negative regulation of cholesterol metabolic process", "d": ["Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0051351", "l": "positive regulation of ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902934", "l": "isopentenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0110021", "l": "cardiac muscle myoblast proliferation", "d": ["The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. 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The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006294", "l": "nucleotide-excision repair, preincision complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0003228", "l": "atrial cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052162", "l": "modulation by symbiont of defense-related host calcium ion flux", "d": ["Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021613", "l": "facial nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060087", "l": "relaxation of vascular associated smooth muscle", "d": ["A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001896", "l": "autolysis", "d": ["A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0070269", "l": "pyroptosis", "d": ["A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905041", "l": "regulation of epithelium regeneration", "d": ["Any process that modulates the frequency, rate or extent of epithelium regeneration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0050686", "l": "negative regulation of mRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099008", "l": "symbiont entry into host cell via permeabilization of inner membrane", "d": ["The entry of a symbiont into the cytoplasm of a host cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. This process mediates the entry of some non-enveloped viruses into prokaryotic cells. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization and permeabilization of the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.054967706738452", "identifiers": [{"i": "GO:0048827", "l": "phyllome development", "d": ["The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. 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Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902247", "l": "geranylgeranyl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061185", "l": "negative regulation of dermatome development", "d": ["Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.97739419478313", "identifiers": [{"i": "GO:0034767", "l": "positive regulation of monoatomic ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.976908003308438", "identifiers": [{"i": "GO:0015772", "l": "oligosaccharide transport", "d": ["The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071584", "l": "negative regulation of zinc ion transmembrane import", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006785", "l": "heme B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905179", "l": "negative regulation of cardiac muscle tissue regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0030852", "l": "regulation of granulocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of granulocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0001752", "l": "compound eye photoreceptor fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. 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Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002229", "l": "defense response to oomycetes", "d": ["Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018406", "l": "protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan", "d": ["The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0050655", "l": "dermatan sulfate proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905642", "l": "negative regulation of DNA methylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001315", "l": "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904014", "l": "response to serotonin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071469", "l": "cellular response to alkaline pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042532", "l": "negative regulation of tyrosine phosphorylation of STAT protein", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072730", "l": "response to papulacandin B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0008594", "l": "photoreceptor cell morphogenesis", "d": ["The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0019323", "l": "pentose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046741", "l": "transport of virus in host, tissue to tissue", "d": ["The transport of a virus between tissues in a multicellular organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009788", "l": "negative regulation of abscisic acid-activated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905794", "l": "response to puromycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0031644", "l": "regulation of nervous system process", "d": ["Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061885", "l": "positive regulation of mini excitatory postsynaptic potential", "d": ["Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. 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Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016488", "l": "farnesol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010839", "l": "negative regulation of keratinocyte proliferation", "d": ["Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901223", "l": "negative regulation of non-canonical NF-kappaB signal transduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical NF-kappaB signaling cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048460", "l": "flower formation", "d": ["The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006421", "l": "asparaginyl-tRNA aminoacylation", "d": ["The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046498", "l": "S-adenosylhomocysteine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0002793", "l": "positive regulation of peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of peptide secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001953", "l": "negative regulation of cell-matrix adhesion", "d": ["Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000413", "l": "protein peptidyl-prolyl isomerization", "d": ["The modification of a protein by cis-trans isomerization of a proline residue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0046470", "l": "phosphatidylcholine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903492", "l": "response to acetylsalicylate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046588", "l": "negative regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003251", "l": "positive regulation of cell proliferation involved in heart valve morphogenesis", "d": ["Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000233", "l": "negative regulation of rRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0042401", "l": "biogenic amine biosynthetic process", "d": ["The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042955", "l": "dextrin transport", "d": ["The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0110072", "l": "apical constriction involved in ventral furrow formation", "d": ["The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902346", "l": "meiotic strand displacement involved in double-strand break repair via SDSA", "d": ["Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060691", "l": "epithelial cell maturation involved in salivary gland development", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902996", "l": "regulation of neurofibrillary tangle assembly", "d": ["Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0009639", "l": "response to red or far red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901252", "l": "regulation of intracellular transport of viral material", "d": ["Any process that modulates the frequency, rate or extent of egress of virus within host cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035582", "l": "sequestering of BMP in extracellular matrix", "d": ["Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010424", "l": "DNA methylation on cytosine within a CG sequence", "d": ["The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0070509", "l": "calcium ion import", "d": ["The directed movement of calcium ions into a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097115", "l": "neurexin clustering involved in presynaptic membrane assembly", "d": ["The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071596", "l": "ubiquitin-dependent protein catabolic process via the N-end rule pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014871", "l": "cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106129", "l": "positive regulation of store-operated calcium entry", "d": ["Any process that activates or increases the frequency, rate or extent of store-operated calcium entry."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019598", "l": "(R)-mandelate catabolic process to catechol", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000645", "l": "negative regulation of receptor catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010895", "l": "negative regulation of ergosterol biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.024411547311772", "identifiers": [{"i": "GO:0031334", "l": "positive regulation of protein-containing complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of protein complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097751", "l": "spore-bearing structure formation", "d": ["The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0035788", "l": "cell migration involved in metanephros development", "d": ["The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902948", "l": "negative regulation of tau-protein kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090164", "l": "asymmetric Golgi ribbon formation", "d": ["The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900951", "l": "negative regulation of 18-methylnonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006264", "l": "mitochondrial DNA replication", "d": ["The process in which new strands of DNA are synthesized in the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051548", "l": "negative regulation of keratinocyte migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904107", "l": "protein localization to microvillus membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a microvillus membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042948", "l": "salicin transport", "d": ["The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0070592", "l": "cell wall polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060862", "l": "negative regulation of floral organ abscission", "d": ["Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003064", "l": "regulation of heart rate by hormone", "d": ["The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072296", "l": "specification of metanephric loop of Henle identity", "d": ["The process in which the loop of Henle of the metanephric nephron acquires its identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900836", "l": "positive regulation of emericellin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060951", "l": "neural crest-derived cardiac glial cell differentiation", "d": ["The process in which a neural crest cell acquires the specialized features of a glial cell of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021521", "l": "ventral spinal cord interneuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007561", "l": "imaginal disc eversion", "d": ["The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0110053", "l": "regulation of actin filament organization", "d": ["Any process that modulates the frequency, rate or extent of actin filament organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001280", "l": "positive regulation of unsaturated fatty acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097699", "l": "vascular endothelial cell response to fluid shear stress", "d": ["Any response to fluid shear stress in a vascular endothelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072090", "l": "mesenchymal stem cell proliferation involved in nephron morphogenesis", "d": ["The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097345", "l": "mitochondrial outer membrane permeabilization", "d": ["The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900246", "l": "positive regulation of RIG-I signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060492", "l": "lung induction", "d": ["The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.151319539368089", "identifiers": [{"i": "GO:0030865", "l": "cortical cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150145", "l": "positive regulation of CD80 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0018117", "l": "protein adenylylation", "d": ["The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0045807", "l": "positive regulation of endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000356", "l": "regulation of kidney smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:2000968", "l": "positive regulation of cell wall polysaccharide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036521", "l": "modulation by symbiont of host protein localization to phagocytic vesicle", "d": ["Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0003164", "l": "His-Purkinje system development", "d": ["The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. 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This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0003056", "l": "regulation of vascular associated smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of vascular smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905281", "l": "positive regulation of retrograde transport, endosome to Golgi", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071925", "l": "thymic stromal lymphopoietin production", "d": ["The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075256", "l": "regulation of teliospore formation", "d": ["Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010089", "l": "xylem development", "d": ["The formation of the principal water-conducting tissue of a vascular plant."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048098", "l": "antennal joint development", "d": ["The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. 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Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901529", "l": "positive regulation of anion channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of anion channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0072049", "l": "comma-shaped body morphogenesis", "d": ["The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015990", "l": "electron transport coupled proton transport", "d": ["The transport of protons against an electrochemical gradient, using energy from electron transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003335", "l": "corneocyte development", "d": ["The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. 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Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900282", "l": "regulation of cellobiose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellobiose catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000192", "l": "negative regulation of fatty acid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002364", "l": "NK T cell lineage commitment", "d": ["The process in which a pro-T cell becomes committed to becoming an NK T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.94491541094456", "identifiers": [{"i": "GO:0019219", "l": "regulation of nucleobase-containing compound metabolic process", "d": ["Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990697", "l": "protein depalmitoleylation", "d": ["The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901613", "l": "negative regulation of terminal button organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002505", "l": "antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071358", "l": "cellular response to type III interferon", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.672771840408203", "identifiers": [{"i": "GO:0060632", "l": "regulation of microtubule-based movement", "d": ["Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009825", "l": "multidimensional cell growth", "d": ["The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0001710", "l": "mesodermal cell fate commitment", "d": ["The cell differentiation process that results in commitment of a cell to become part of the mesoderm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000216", "l": "positive regulation of proline metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of proline metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032714", "l": "negative regulation of interleukin-5 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022620", "l": "microgametophyte vegetative cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a microgametophyte. The microgametophyte vegetative cell gives rise to the pollen tube."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032516", "l": "positive regulation of phosphoprotein phosphatase activity", "d": ["Any process that activates or increases the activity of a phosphoprotein phosphatase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051335", "l": "meiosis II nuclear membrane reassembly", "d": ["The reformation of the nuclear membrane during meiosis II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033072", "l": "vancomycin biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0045776", "l": "negative regulation of blood pressure", "d": ["Any process in which the force of blood traveling through the circulatory system is decreased."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003426", "l": "cytoskeleton polarization involved in growth plate cartilage chondrocyte division", "d": ["A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0001845", "l": "phagolysosome assembly", "d": ["The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035703", "l": "monocyte migration into blood stream", "d": ["The movement of a monocyte from the bone marrow to the blood stream."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.864810576236323", "identifiers": [{"i": "GO:2000241", "l": "regulation of reproductive process", "d": ["Any process that modulates the frequency, rate or extent of reproductive process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061869", "l": "regulation of hepatic stellate cell migration", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021949", "l": "brainstem precerebellar neuron precursor migration", "d": ["The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061078", "l": "positive regulation of prostaglandin secretion involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900587", "l": "arugosin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arugosin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009168", "l": "purine ribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902066", "l": "regulation of cell wall pectin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045898", "l": "regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097332", "l": "response to antipsychotic drug", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016267", "l": "O-glycan processing, core 1", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901776", "l": "mitomycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mitomycin C."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.266332550043785", "identifiers": [{"i": "GO:0006821", "l": "chloride transport", "d": ["The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902917", "l": "positive regulation of mating projection assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mating projection assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0036503", "l": "ERAD pathway", "d": ["The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. 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The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071432", "l": "peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion", "d": ["The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0072102", "l": "glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the glomerulus are generated and organized. 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Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030034", "l": "microvillar actin bundle assembly", "d": ["Assembly of the parallel bundle of actin filaments at the core of a microvillus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032877", "l": "positive regulation of DNA endoreduplication", "d": ["Any process that activates or increases the frequency, rate or extent of DNA endoreduplication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006378", "l": "mRNA polyadenylation", "d": ["The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031848", "l": "protection from non-homologous end joining at telomere", "d": ["A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.449113659480474", "identifiers": [{"i": "GO:0060179", "l": "male mating behavior", "d": ["The specific behavior of a male organism that is associated with reproduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.842472375198142", "identifiers": [{"i": "GO:0071478", "l": "cellular response to radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003066", "l": "positive regulation of heart rate by norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044417", "l": "translocation of molecules into host", "d": ["The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032232", "l": "negative regulation of actin filament bundle assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904837", "l": "beta-catenin-TCF complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0050773", "l": "regulation of dendrite development", "d": ["Any process that modulates the frequency, rate or extent of dendrite development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060526", "l": "prostate glandular acinus morphogenesis", "d": ["The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044489", "l": "negative regulation of voltage-gated sodium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071318", "l": "cellular response to ATP", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002099", "l": "tRNA wobble guanine modification", "d": ["The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140734", "l": "ammonium excretion", "d": ["The elimination of ammonium ions from an excretory cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0099188", "l": "postsynaptic cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0052316", "l": "phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0000765", "l": "response to pheromone regulating pheromone-induced unidirectional conjugation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001800", "l": "negative regulation of type IIb hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007436", "l": "larval salivary gland morphogenesis", "d": ["The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0052026", "l": "symbiont-mediated perturbation of host transcription", "d": ["A process in which a symbiont alters or subverts transcription in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900092", "l": "negative regulation of raffinose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010414", "l": "glucuronoarabinoxylan metabolic process", "d": ["The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035208", "l": "positive regulation of hemocyte proliferation", "d": ["Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903040", "l": "exon-exon junction complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019656", "l": "glucose catabolic process to D-lactate and ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010146", "l": "fructan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051057", "l": "positive regulation of small GTPase mediated signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042690", "l": "negative regulation of crystal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090200", "l": "positive regulation of release of cytochrome c from mitochondria", "d": ["Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090648", "l": "response to environmental enrichment", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.492767218801774", "identifiers": [{"i": "GO:0140014", "l": "mitotic nuclear division", "d": ["A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032820", "l": "regulation of natural killer cell proliferation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006616", "l": "SRP-dependent cotranslational protein targeting to membrane, translocation", "d": ["The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901924", "l": "positive regulation of sclerotium development", "d": ["Any process that activates or increases the frequency, rate or extent of sclerotium development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043638", "l": "puromycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0050871", "l": "positive regulation of B cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of B cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:1905517", "l": "macrophage migration", "d": ["The orderly movement of a macrophage from one site to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060962", "l": "regulation of ribosomal protein gene transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090521", "l": "podocyte cell migration", "d": ["The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. 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Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070830", "l": "bicellular tight junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0000957", "l": "mitochondrial RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009253", "l": "peptidoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046396", "l": "D-galacturonate metabolic process", "d": ["The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007347", "l": "regulation of preblastoderm mitotic cell cycle", "d": ["A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000103", "l": "positive regulation of mammary stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036167", "l": "phenotypic switching in response to host", "d": ["A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021530", "l": "spinal cord oligodendrocyte cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018343", "l": "protein farnesylation", "d": ["The covalent attachment of a farnesyl group to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0098732", "l": "macromolecule deacylation", "d": ["The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021577", "l": "hindbrain structural organization", "d": ["The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. 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Type III interferon is also known as interferon-lambda."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034129", "l": "positive regulation of MyD88-independent toll-like receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0045026", "l": "plasma membrane fusion", "d": ["The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035519", "l": "protein K29-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. 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Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0120247", "l": "acetylenic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0098513", "l": "detection of humidity", "d": ["The series of events in which a humidity stimulus is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0044344", "l": "cellular response to fibroblast growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090121", "l": "low-density lipoprotein particle disassembly involved in cholesterol transport", "d": ["The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009137", "l": "purine nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003326", "l": "pancreatic A cell fate commitment", "d": ["The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. 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The fundus is the portion of the stomach that lies above the cardiac notch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000622", "l": "regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0001657", "l": "ureteric bud development", "d": ["The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035698", "l": "CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["The migration of a CD8-positive, alpha-beta cytotoxic T cell from the 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"identifiers": [{"i": "GO:0015739", "l": "sialic acid transport", "d": ["The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046869", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide", "d": ["The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060302", "l": "negative regulation of cytokine activity", "d": ["Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": 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These cells are slender bipolar cells of the developing marginal zone. 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The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032599", "l": "protein transport out of membrane raft", "d": ["The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071257", "l": "cellular response to electrical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046584", "l": "enniatin metabolic process", "d": ["The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051658", "l": "maintenance of nucleus location", "d": ["Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046275", "l": "flavonoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.300618254768168", "identifiers": [{"i": "GO:0006837", "l": "serotonin transport", "d": ["The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002622", "l": "regulation of B cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0097036", "l": "regulation of plasma membrane sterol distribution", "d": ["Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903788", "l": "positive regulation of glutathione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900998", "l": "nitrobenzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitrobenzene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903910", "l": "negative regulation of receptor clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0072679", "l": "thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1903421", "l": "regulation of synaptic vesicle recycling", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle recycling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006233", "l": "dTDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001514", "l": "selenocysteine incorporation", "d": ["The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045918", "l": "negative regulation of cytolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0000752", "l": "agglutination involved in conjugation with cellular fusion", "d": ["The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071491", "l": "cellular response to red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.962639558314571", "identifiers": [{"i": "GO:0019953", "l": "sexual reproduction", "d": ["A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902953", "l": "positive regulation of ER to Golgi vesicle-mediated transport", "d": ["Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0007431", "l": "salivary gland development", "d": ["The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0062121", "l": "linear element maturation", "d": ["The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032402", "l": "melanosome transport", "d": ["The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001060", "l": "D-glycero-D-manno-heptose 7-phosphate metabolic process", "d": ["The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904094", "l": "positive regulation of autophagic cell death", "d": ["Any process that activates or increases the frequency, rate or extent of autophagic cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0043525", "l": "positive regulation of neuron apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2001237", "l": "negative regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904277", "l": "negative regulation of wax biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000621", "l": "regulation of DNA replication termination", "d": ["Any process that modulates the frequency, rate or extent of DNA replication termination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009446", "l": "putrescine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.064276464374601", "identifiers": [{"i": "GO:0040008", "l": "regulation of growth", "d": ["Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:1903524", "l": "positive regulation of blood circulation", "d": ["Any process that activates or increases the frequency, rate or extent of blood circulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0052804", "l": "nitroimidazole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034517", "l": "ribophagy", "d": ["The selective degradation of mature ribosomes by macroautophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.28303470654965", "identifiers": [{"i": "GO:0065003", "l": "protein-containing complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.098012012402094", "identifiers": [{"i": "GO:0051047", "l": "positive regulation of secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000973", "l": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "d": ["The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900871", "l": "chloroplast mRNA modification", "d": ["The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1903798", "l": "regulation of miRNA processing", "d": ["Any process that modulates the frequency, rate or extent of microRNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905536", "l": "negative regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051497", "l": "negative regulation of stress fiber assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019515", "l": "lactose catabolic process via UDP-galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0043153", "l": "entrainment of circadian clock by photoperiod", "d": ["The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0070613", "l": "regulation of protein processing", "d": ["Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035922", "l": "foramen ovale closure", "d": ["The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060030", "l": "dorsal convergence", "d": ["The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031388", "l": "organic acid phosphorylation", "d": ["The process of introducing one or more phosphate groups into an organic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032828", "l": "positive regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0048143", "l": "astrocyte activation", "d": ["A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.300845054119293", "identifiers": [{"i": "GO:0007127", "l": "meiosis I", "d": ["The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0009637", "l": "response to blue light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002030", "l": "inhibitory G protein-coupled receptor phosphorylation", "d": ["The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0060600", "l": "dichotomous subdivision of an epithelial terminal unit", "d": ["The process in which an epithelial cord, rod or tube bifurcates at its end."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000719", "l": "photoreactive repair", "d": ["The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051299", "l": "centrosome separation", "d": ["The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0050829", "l": "defense response to Gram-negative bacterium", "d": ["Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0002483", "l": "antigen processing and presentation of endogenous peptide antigen", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106297", "l": "E-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042983", "l": "amyloid precursor protein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.620660560393524", "identifiers": [{"i": "GO:0044403", "l": "biological process involved in symbiotic interaction", "d": ["A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0051340", "l": "regulation of ligase activity", "d": ["Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000485", "l": "regulation of glutamine transport", "d": ["Any process that modulates the frequency, rate or extent of glutamine transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042121", "l": "alginic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000013", "l": "regulation of arginine biosynthetic process via ornithine", "d": ["Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1902668", "l": "negative regulation of axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901157", "l": "neomycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neomycin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003297", "l": "heart wedging", "d": ["The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.740683062540427", "identifiers": [{"i": "GO:0061061", "l": "muscle structure development", "d": ["The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003292", "l": "cardiac septum cell differentiation", "d": ["The process in which an endocardial cushion cell becomes a cell of a cardiac septum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051770", "l": "positive regulation of nitric-oxide synthase biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.271174895061641", "identifiers": [{"i": "GO:0048871", "l": "multicellular organismal-level homeostasis", "d": ["Any process involved in the maintenance of an internal steady state at the level of the multicellular organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080157", "l": "regulation of plant-type cell wall organization or biogenesis", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070802", "l": "regulation of metula development", "d": ["Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0002885", "l": "positive regulation of hypersensitivity", "d": ["Any process that activates or increases the frequency, rate, or extent of hypersensitivity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0051323", "l": "metaphase", "d": ["The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120306", "l": "cellular response to actin cytoskeletal stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007377", "l": "germ-band extension", "d": ["Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. 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The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019548", "l": "arginine catabolic process to spermine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010987", "l": "negative regulation of high-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. 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This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1900426", "l": "positive regulation of defense response to bacterium", "d": ["Any process that activates or increases the frequency, rate or extent of defense response to bacterium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905530", "l": "negative regulation of uracil import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060877", "l": "regionalization involved in semicircular canal formation", "d": ["The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019286", "l": "glycine betaine biosynthetic process from glycine", "d": ["The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072216", "l": "positive regulation of metanephros development", "d": ["Any process that increases the rate, frequency or extent of metanephros development. 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"d": ["The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. 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It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071356", "l": "cellular response to tumor necrosis factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903373", "l": "positive regulation of endoplasmic reticulum tubular network organization", "d": ["Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.836106170294514", "identifiers": [{"i": "GO:0045088", "l": "regulation of innate immune 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cibarial plate morphogenesis", "d": ["The process in which the anatomical structures of the anterior cibarial plate are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0042762", "l": "regulation of sulfur metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0120126", "l": "response to copper ion starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043415", "l": "positive regulation of skeletal muscle tissue regeneration", "d": ["Any process that activates or increase the rate of skeletal muscle regeneration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043556", "l": "regulation of translation in response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140237", "l": "translation at presynapse, modulating chemical synaptic transmission", "d": ["Translation that occurs at the presynapse, and that modulates chemical synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0086046", "l": "membrane depolarization during SA node cell action potential", "d": ["The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090246", "l": "convergent extension involved in somitogenesis", "d": ["The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070607", "l": "regulation of cell wall (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, 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{"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071354", "l": "cellular response to interleukin-6", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0052805", "l": "imidazole-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000934", "l": "negative regulation of cellotriose metabolic process", "d": ["Any process that stops, prevents or 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"GO:0043463", "l": "regulation of rhamnose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0098887", "l": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "d": ["The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010973", "l": "positive regulation of division septum assembly", "d": ["Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006948", "l": "induction by virus of host cell-cell fusion", "d": ["The process of syncytia-forming cell-cell fusion, caused by a virus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902243", "l": "copal-8-ol diphosphate(3-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034230", "l": "enkephalin processing", "d": ["The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904002", "l": "regulation of sebum secreting cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043643", "l": "tetracycline metabolic process", "d": ["The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030708", "l": "germarium-derived female germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060681", "l": "branch elongation involved in ureteric bud branching", "d": ["The growth of a branch of the ureteric bud along its axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901422", "l": "response to butan-1-ol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:2000100", "l": "regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032251", "l": "positive regulation of adenosine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0090316", "l": "positive regulation of intracellular protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.161717068681156", "identifiers": [{"i": "GO:1902742", "l": "apoptotic process involved in development", "d": ["Any apoptotic process that is involved in anatomical structure development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106016", "l": "positive regulation of inflammatory response to wounding", "d": ["Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046101", "l": "hypoxanthine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. 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The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901056", "l": "trimethylenediamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trimethylenediamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0018058", "l": "N-terminal protein amino acid deamination, from amino carbon", "d": ["The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.528207968973732", "identifiers": [{"i": "GO:0042440", "l": "pigment metabolic process", "d": ["The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010809", "l": "negative regulation of synaptic vesicle priming", "d": ["Any process that decreases the frequency, rate or extent of synaptic vesicle priming. 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Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0061339", "l": "establishment or maintenance of monopolar cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0061371", "l": "determination of heart left/right asymmetry", "d": ["Determination of the asymmetric location of the heart with respect to the left and right halves of the organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097656", "l": "cell-cell self recognition", "d": ["A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018178", "l": "peptidyl-threonine adenylylation", "d": ["The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0006953", "l": "acute-phase response", "d": ["An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021780", "l": "glial cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.876091073600094", "identifiers": [{"i": "GO:0007097", "l": "nuclear migration", "d": ["The directed movement of the nucleus to a specific location within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901181", "l": "negative regulation of cellular response to caffeine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0021680", "l": "cerebellar Purkinje cell layer development", "d": ["The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.33144287441435", "identifiers": [{"i": "GO:2000514", "l": "regulation of CD4-positive, alpha-beta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "28.221278531244121", "identifiers": [{"i": "GO:0007275", "l": "multicellular organism development", "d": ["The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045450", "l": "bicoid mRNA localization", "d": ["Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0043213", "l": "bacteriocin transport", "d": ["The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035132", "l": "post-embryonic medial fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904754", "l": "positive regulation of vascular associated smooth muscle cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048139", "l": "female germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070073", "l": "clustering of voltage-gated calcium channels", "d": ["The process in which voltage-gated calcium channels become localized together in high densities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002873", "l": "positive regulation of natural killer cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060921", "l": "sinoatrial node cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. 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This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050676", "l": "negative regulation of urothelial cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032246", "l": "regulation of pyrimidine nucleoside transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0036016", "l": "cellular response to interleukin-3", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0085029", "l": "extracellular matrix assembly", "d": ["The aggregation, arrangement and bonding together of the extracellular matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902514", "l": "regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901620", "l": "regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903652", "l": "modulation by virus of host cytoplasmic transport", "d": ["Modulation by an infecting virus of host cytoplasmic transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006391", "l": "transcription initiation at mitochondrial promoter", "d": ["A transcription initiation process that takes place at a promoter on the mitochondrial chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002129", "l": "wobble position guanine ribose methylation", "d": ["The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0043137", "l": "DNA replication, removal of RNA primer", "d": ["Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045124", "l": "regulation of bone resorption", "d": ["Any process that modulates the frequency, rate or extent of bone tissue loss (resorption)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002932", "l": "tendon sheath development", "d": ["The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. 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It permits the tendon to move."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:1905770", "l": "regulation of mesodermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesodermal cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046000", "l": "positive regulation of ecdysteroid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016270", "l": "O-glycan processing, core 4", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048853", "l": "forebrain morphogenesis", "d": ["The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0072114", "l": "pronephros morphogenesis", "d": ["The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0035162", "l": "embryonic hemopoiesis", "d": ["The stages of blood cell formation that take place within the embryo."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019990", "l": "pteridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034355", "l": "NAD salvage", "d": ["Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033132", "l": "negative regulation of glucokinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141123", "l": "dermonecrosis in another organism", "d": ["The disruption of the skin of another organism, leading to damage or temporary subversion of the skin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035490", "l": "regulation of leukotriene production involved in inflammatory response", "d": ["Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042727", "l": "flavin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045832", "l": "positive regulation of light-activated channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of light-activated channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0106259", "l": "cell-to-cell migration in host", "d": ["The directional movement of a symbiont from one host cell to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048851", "l": "hypophysis formation", "d": ["The process in which the anatomical structures of the hypophysis are generated and organized. 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It is also the demethylated biosynthetic precursor of epinephrine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031621", "l": "negative regulation of fever generation", "d": ["Any process that stops, prevents, or reduces the rate or extent of fever generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0070596", "l": "(1->3)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048262", "l": "determination of dorsal/ventral asymmetry", "d": ["Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1905405", "l": "regulation of mitotic cohesin loading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin loading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.33144287441435", "identifiers": [{"i": "GO:0051325", "l": "interphase", "d": ["The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0016077", "l": "sno(s)RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904129", "l": "positive regulation of convergent extension involved in somitogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017187", "l": "peptidyl-glutamic acid carboxylation", "d": ["The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030860", "l": "regulation of polarized epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0043954", "l": "cellular component maintenance", "d": ["The organization process that preserves a cellular component in a stable functional or structural state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0033334", "l": "fin morphogenesis", "d": ["The process in which the anatomical structures of a fin are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019288", "l": "isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043310", "l": "negative regulation of eosinophil degranulation", "d": ["Any process that stops, prevents, or reduces the rate of eosinophil degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1903977", "l": "positive regulation of glial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of glial cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035634", "l": "response to stilbenoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0120187", "l": "positive regulation of protein localization to chromatin", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to chromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009853", "l": "photorespiration", "d": ["A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1901027", "l": "dextrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dextrin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001192", "l": "negative regulation of gamma-delta T cell activation involved in immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021788", "l": "chemoattraction of branchiomotor neuron axon in neural tube", "d": ["The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003328", "l": "pancreatic D cell fate commitment", "d": ["The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. 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This is the first sign of anterior-posterior asymmetry in the developing egg chamber."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097698", "l": "telomere maintenance via base-excision repair", "d": ["A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. 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Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031948", "l": "positive regulation of glucocorticoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035043", "l": "male pronuclear envelope synthesis", "d": ["Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0003379", "l": "establishment of cell polarity involved in gastrulation cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019416", "l": "polythionate oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900862", "l": "negative regulation of cordyol C biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903165", "l": "response to polycyclic arene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0043928", "l": "exonucleolytic catabolism of deadenylated mRNA", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000939", "l": "regulation of plant-type cell wall cellulose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007522", "l": "visceral muscle development", "d": ["The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001177", "l": "negative regulation of mediator complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000025", "l": "maltose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0015760", "l": "glucose-6-phosphate transport", "d": ["The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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See embryonic development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0018119", "l": "peptidyl-cysteine S-nitrosylation", "d": ["The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045006", "l": "DNA deamination", "d": ["The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905700", "l": "negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. 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Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. 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An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1903430", "l": "negative regulation of cell maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006679", "l": "glucosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.442928046420938", "identifiers": [{"i": "GO:0043207", "l": "response to external biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.15061240728128", "identifiers": [{"i": "GO:0002252", "l": "immune effector process", "d": ["Any process of the immune system that executes a component of an immune response. 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Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0002341", "l": "central B cell anergy", "d": ["Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044659", "l": "viral release from host cell by cytolysis", "d": ["The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140027", "l": "contractile vacuole localization", "d": ["The directed movement of the contractile vacuole to a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901392", "l": "regulation of transforming growth factor beta1 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905559", "l": "positive regulation of mitotic nuclear envelope disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021617", "l": "glossopharyngeal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. 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The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902999", "l": "negative regulation of phospholipid efflux", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014716", "l": "skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration", "d": ["Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0048866", "l": "stem cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. 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A mesonephric duct is a tube that drains the mesonephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019877", "l": "diaminopimelate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0035287", "l": "head segmentation", "d": ["Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. 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"identifiers": [{"i": "GO:1903122", "l": "negative regulation of TRAIL-activated apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0040040", "l": "thermosensory behavior", "d": ["Behavior that is dependent upon the sensation of temperature."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052838", "l": "thiazole metabolic process", "d": ["The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901221", "l": "positive regulation of cardiac chamber morphogenesis", 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Conjugation requires direct cellular contact between the organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032721", "l": "negative regulation of lymphotoxin A production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901039", "l": "regulation of peptide antigen transport", "d": ["Any process that modulates the frequency, rate or extent of peptide antigen transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060370", "l": "susceptibility to T cell mediated cytotoxicity", "d": ["The process of causing a cell to become susceptible to T cell mediated cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042423", "l": "catecholamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072030", "l": "short nephron development", "d": ["The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. 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The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905951", "l": "mitochondrion DNA recombination", "d": ["Any DNA recombination that takes place in mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0070199", "l": "establishment of protein localization to chromosome", "d": ["The directed movement of a protein to a specific location on a chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060808", "l": "positive regulation of mesodermal to mesenchymal transition involved in gastrulation", "d": ["Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120266", "l": "positive regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901123", "l": "bacitracin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bacitracin A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160036", "l": "positive regulation of postsynaptic density assembly", "d": ["Any process that activates or increases the frequency, rate or extent of postsynaptic density assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0046519", "l": "sphingoid metabolic process", "d": ["The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035170", "l": "lymph gland crystal cell differentiation", "d": ["The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045210", "l": "FasL biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.976908003308438", "identifiers": [{"i": "GO:0006650", "l": "glycerophospholipid metabolic process", "d": ["The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.314050959231352", "identifiers": [{"i": "GO:0071852", "l": "fungal-type cell wall organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0035316", "l": "non-sensory hair organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0070654", "l": "sensory epithelium regeneration", "d": ["The regrowth of a sensory epithelium following its loss or destruction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072343", "l": "pancreatic stellate cell proliferation", "d": ["The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. 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Probably acts to prevent subsequent matings by other males."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0007392", "l": "initiation of dorsal closure", "d": ["Events that occur at the start of dorsal closure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002417", "l": "B cell antigen processing and presentation mediated by B cell receptor uptake of antigen", "d": ["B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042870", "l": "D-glucarate transmembrane transport", "d": ["The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1904526", "l": "regulation of microtubule binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0008291", "l": "acetylcholine metabolic process", "d": ["The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. 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It also acts as a paracrine signal in various non-neural tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061355", "l": "Wnt protein secretion", "d": ["The controlled release of a Wnt protein from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051080", "l": "meiosis II nuclear membrane disassembly", "d": ["The controlled breakdown of the nuclear membranes during the second division of meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035396", "l": "positive regulation of chemokine (C-X-C motif) ligand 9 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901250", "l": "negative regulation of lung goblet cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043378", "l": "positive regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0009555", "l": "pollen development", "d": ["The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. 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In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0039017", "l": "pattern specification involved in pronephros development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070307", "l": "lens fiber cell development", "d": ["The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0019853", "l": "L-ascorbic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.292831226590629", "identifiers": [{"i": "GO:0008610", "l": "lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000611", "l": "positive regulation of thyroid hormone generation", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid hormone generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060970", "l": "embryonic heart tube dorsal/ventral pattern formation", "d": ["The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045886", "l": "negative regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061168", "l": "regulation of hair follicle placode formation", "d": ["Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036046", "l": "protein demalonylation", "d": ["The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015715", "l": "nucleotide-sulfate transport", "d": ["The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009876", "l": "pollen adhesion", "d": ["The process in which pollen deposited on the stigma adheres to cells of the stigma."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0000052", "l": "citrulline metabolic process", "d": ["The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060270", "l": "main body follicle cell migration", "d": ["The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006771", "l": "riboflavin metabolic process", "d": ["The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072184", "l": "renal vesicle progenitor cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052159", "l": "perturbation of host induced systemic resistance", "d": ["A process in which an organism effects a change that affects the induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902223", "l": "erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035965", "l": "cardiolipin acyl-chain remodeling", "d": ["Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062142", "l": "L-beta-ethynylserine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. 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They are the product of esterification between a carboxylic acid and a thiol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120273", "l": "ciliary centrin arm assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061159", "l": "establishment of bipolar cell polarity involved in cell morphogenesis", "d": ["The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. 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UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903355", "l": "negative regulation of distal tip cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0086028", "l": "bundle of His cell to Purkinje myocyte signaling", "d": ["Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0051480", "l": "regulation of cytosolic calcium ion concentration", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090394", "l": "negative regulation of excitatory postsynaptic potential", "d": ["Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0022615", "l": "protein to membrane docking", "d": ["The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. 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Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002748", "l": "antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen", "d": ["Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010813", "l": "neuropeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neuropeptides. 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Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039016", "l": "cell-cell signaling involved in pronephros development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000837", "l": "regulation of androstenedione secretion", "d": ["Any process that modulates the frequency, rate or extent of androstenedione secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1904889", "l": "regulation of excitatory synapse assembly", "d": ["Any process that modulates the frequency, rate or extent of excitatory synapse assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.653457143972261", "identifiers": [{"i": "GO:0019184", "l": "nonribosomal peptide biosynthetic process", "d": ["The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002552", "l": "serotonin secretion by mast cell", "d": ["The regulated release of serotonin by a mast cell or group of mast cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0097278", "l": "complement-dependent cytotoxicity", "d": ["Cell killing caused by the membrane attack complex formed following complement activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010536", "l": "positive regulation of activation of Janus kinase activity", "d": ["Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:1990399", "l": "epithelium regeneration", "d": ["The regrowth of lost or destroyed epithelium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070135", "l": "beta-1,2-oligomannoside metabolic process", "d": ["The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071768", "l": "mycolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905154", "l": "negative regulation of membrane invagination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072245", "l": "metanephric glomerular parietal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. 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Abaxial refers to being situated away from an axis of an anatomical structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900493", "l": "positive regulation of [4Fe-4S] cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150045", "l": "regulation of synaptic signaling by nitric oxide", "d": ["Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901864", "l": "capsorubin metabolic process", "d": ["The chemical reactions and pathways involving capsorubin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901995", "l": "positive regulation of meiotic cell cycle phase transition", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045719", "l": "negative regulation of glycogen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036339", "l": "lymphocyte adhesion to endothelial cell of high endothelial venule", "d": ["The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031171", "l": "ferricrocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.653457143972261", "identifiers": [{"i": "GO:0006505", "l": "GPI anchor metabolic process", "d": ["The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060723", "l": "regulation of cell proliferation involved in embryonic placenta development", "d": ["Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032692", "l": "negative regulation of interleukin-1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900797", "l": "cordyol C metabolic process", "d": ["The chemical reactions and pathways involving cordyol C."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021819", "l": "layer formation in cerebral cortex", "d": ["The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0014820", "l": "tonic smooth muscle contraction", "d": ["A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900291", "l": "regulation of galactotriose transport", "d": ["Any process that modulates the frequency, rate or extent of galactotriose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021980", "l": "subpallium cell migration", "d": ["The orderly movement of cells from one site to another in the subpallium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032614", "l": "interleukin-11 production", "d": ["The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009102", "l": "biotin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902167", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0036162", "l": "oxytocin production", "d": ["The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008071", "l": "maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded", "d": ["Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0061008", "l": "hepaticobiliary system development", "d": ["The progression of the hepaticobiliary system over time, from its formation to the mature structure. 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This occurs as part of the regulation of muscle adaptation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0120034", "l": "positive regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042676", "l": "compound eye cone cell fate commitment", "d": ["The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990882", "l": "rRNA acetylation", "d": ["The modification of rRNA structure by addition of an acetyl group to rRNA. 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Disaccharides are sugars composed of two monosaccharide units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904844", "l": "response to L-glutamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106022", "l": "positive regulation of vesicle docking", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle docking."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.238207667698568", "identifiers": [{"i": "GO:0060255", "l": "regulation of macromolecule metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900654", "l": "positive regulation of demethylkotanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.864810576236323", "identifiers": [{"i": "GO:0008202", "l": "steroid metabolic process", "d": ["The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.625268296404869", "identifiers": [{"i": "GO:0070647", "l": "protein modification by small protein conjugation or removal", "d": ["A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0034587", "l": "piRNA processing", "d": ["A process leading to the generation of a functional piRNA. piRNAs (Piwi-associated RNAs) are a class of 24- to 30-nucleotide RNAs derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071602", "l": "phytosphingosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021886", "l": "hypothalamus gonadotrophin-releasing hormone neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. 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Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0090382", "l": "phagosome maturation", "d": ["A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. 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In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034307", "l": "regulation of ascospore formation", "d": ["Any process that modulates the frequency, rate or extent of ascospore formation. 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The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036392", "l": "chemokine (C-C motif) ligand 20 production", "d": ["The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007407", "l": "neuroblast activation", "d": ["A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009835", "l": "fruit ripening", "d": ["An developmental maturation process that has as participant a fruit. 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Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1900629", "l": "methanophenazine metabolic process", "d": ["The chemical reactions and pathways involving methanophenazine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031460", "l": "glycine betaine transport", "d": ["The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045617", "l": "negative regulation of keratinocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048198", "l": "Golgi vesicle bud deformation and release", "d": ["The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. 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A cardiac myofibril is a myofibril specific to cardiac muscle cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0098718", "l": "serine import across plasma membrane", "d": ["The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061205", "l": "paramesonephric duct development", "d": ["The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.759070281076816", "identifiers": [{"i": "GO:0007588", "l": "excretion", "d": ["The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090301", "l": "negative regulation of neural crest formation", "d": ["Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0045822", "l": "negative regulation of heart contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0000085", "l": "mitotic G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0015961", "l": "diadenosine polyphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002309", "l": "T cell proliferation involved in immune response", "d": ["The expansion of a T cell population by cell division as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007376", "l": "cephalic furrow formation", "d": ["Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1902229", "l": "regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090050", "l": "positive regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0061804", "l": "mitotic spindle formation (spindle phase one)", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042810", "l": "pheromone metabolic process", "d": ["The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098628", "l": "peptidyl-N-phospho-arginine dephosphorylation", "d": ["The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045697", "l": "regulation of synergid differentiation", "d": ["Any process that modulates the frequency, rate or extent of synergid cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902438", "l": "response to vanadate(3-)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904759", "l": "protein localization to equatorial microtubule organizing center", "d": ["A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.835725707519245", "identifiers": [{"i": "GO:0035282", "l": "segmentation", "d": ["The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062176", "l": "R-loop processing", "d": ["A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000353", "l": "positive regulation of endothelial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016345", "l": "female meiotic chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051413", "l": "response to cortisone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097705", "l": "vascular endothelial cell response to pulsatile fluid shear stress", "d": ["Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006718", "l": "juvenile hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000438", "l": "negative regulation of monocyte extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0016339", "l": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "d": ["The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904998", "l": "negative regulation of leukocyte adhesion to arterial endothelial cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0043416", "l": "regulation of skeletal muscle tissue regeneration", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090323", "l": "prostaglandin secretion involved in immune response", "d": ["The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021977", "l": "tectospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005999", "l": "xylulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0002777", "l": "antimicrobial peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010024", "l": "phytochromobilin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045959", "l": "negative regulation of complement activation, classical pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.432554362561859", "identifiers": [{"i": "GO:0006941", "l": "striated muscle contraction", "d": ["A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036215", "l": "response to stem cell factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042774", "l": "plasma membrane ATP synthesis coupled electron transport", "d": ["The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0060005", "l": "vestibular reflex", "d": ["A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045068", "l": "negative extrathymic T cell selection", "d": ["The process of elimination of extrathymically maturing T cells which react strongly with self-antigens."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0090330", "l": "regulation of platelet aggregation", "d": ["Any process that modulates the rate, frequency or extent of platelet aggregation. 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The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.97739419478313", "identifiers": [{"i": "GO:0043632", "l": "modification-dependent macromolecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0001945", "l": "lymph vessel development", "d": ["The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0043374", "l": "CD8-positive, alpha-beta T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014012", "l": "peripheral nervous system axon regeneration", "d": ["The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0071270", "l": "1-butanol metabolic process", "d": ["The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903719", "l": "regulation of I-kappaB phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0018992", "l": "germ-line sex determination", "d": ["The determination of sex and sexual phenotype in an organism's germ line."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904413", "l": "negative regulation of cardiac ventricle development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0009658", "l": "chloroplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035714", "l": "cellular response to nitrogen dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030922", "l": "peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine", "d": ["The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.709179502404908", "identifiers": [{"i": "GO:0009566", "l": "fertilization", "d": ["The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. 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ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900710", "l": "regulation of tensidol B biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905664", "l": "regulation of calcium ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0061552", "l": "ganglion morphogenesis", "d": ["The process in which the anatomical structures of ganglion are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072065", "l": "long descending thin limb bend development", "d": ["The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. 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This process occurs as part of the regulation of muscle adaptation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019422", "l": "disproportionation of elemental sulfur", "d": ["The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0044091", "l": "membrane biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0055115", "l": "entry into diapause", "d": ["The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. 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"identifiers": [{"i": "GO:0044856", "l": "plasma membrane raft localization", "d": ["Any process in which plasma membrane rafts are transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044090", "l": "positive regulation of vacuole organization", "d": ["Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051465", "l": "negative regulation of corticotropin-releasing hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010358", 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[{"i": "GO:1905889", "l": "positive regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0061065", "l": "regulation of dauer larval development", "d": ["Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021739", "l": "mesencephalic trigeminal nucleus development", "d": ["The process 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[{"i": "GO:0070297", "l": "regulation of phosphorelay signal transduction system", "d": ["Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0048366", "l": "leaf development", "d": ["The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048910", "l": "afferent axon development in anterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072716", "l": "response to actinomycin D", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097640", "l": "L-ornithine import across plasma membrane", "d": ["The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060266", "l": "negative regulation of respiratory burst involved in inflammatory response", "d": ["Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901170", "l": "naphthalene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of naphthalene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003095", "l": "pressure natriuresis", "d": ["The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097184", "l": "response to azide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003092", "l": "renal water retention", "d": ["The process in which renal water excretion is decreased."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034224", "l": "cellular response to zinc ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039521", "l": "suppression by virus of host autophagy", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000040", "l": "regulation of planar cell polarity pathway involved in axis elongation", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0007624", "l": "ultradian rhythm", "d": ["The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019488", "l": "ribitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. 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An example of this process is found in Saccharomyces cerevisiae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000918", "l": "regulation of glucuronoarabinoxylan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0016344", "l": "meiotic chromosome movement towards spindle pole", "d": ["The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. 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The embryo sac develops from the megaspore in heterosporous plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044497", "l": "positive regulation of blood pressure in another organism", "d": ["A process by which one organism increases the force with which blood travels through the circulatory system of another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031284", "l": "positive regulation of guanylate cyclase activity", "d": ["Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006711", "l": "estrogen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000385", "l": "positive regulation of ectoderm development", "d": ["Any process that activates or increases the frequency, rate or extent of ectoderm development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061388", "l": "regulation of rate of cell growth", "d": ["Any process that modulates the rate of cell growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0080171", "l": "lytic vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062087", "l": "positive regulation of vein smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of vein smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0090504", "l": "epiboly", "d": ["The expansion of one cell sheet over other cells or yolk."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0060462", "l": "lung lobe development", "d": ["The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902212", "l": "negative regulation of prolactin signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0014044", "l": "Schwann cell development", "d": ["The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0098760", "l": "response to interleukin-7", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.605953599968913", "identifiers": [{"i": "GO:0032943", "l": "mononuclear cell proliferation", "d": ["The expansion of a mononuclear cell population by cell division. 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A metanephric tubule is an epithelial tube that is part of the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061612", "l": "galactose to glucose-1-phosphate metabolic process", "d": ["The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006856", "l": "eye pigment precursor transport", "d": ["The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032702", "l": "negative regulation of interleukin-19 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0042427", "l": "serotonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048690", "l": "regulation of axon extension involved in regeneration", "d": ["Any process that modulates the frequency, rate or extent of axon extension involved in regeneration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903855", "l": "positive regulation of stress response to copper ion", "d": ["Any process that activates or increases the frequency, rate or extent of stress response to copper ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0075317", "l": "ascus development", "d": ["The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903220", "l": "positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051767", "l": "nitric-oxide synthase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002315", "l": "marginal zone B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902873", "l": "negative regulation of horizontal cell localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0044553", "l": "modulation of biological quality in another organism", "d": ["Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905212", "l": "positive regulation of fibroblast chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900660", "l": "positive regulation of emericellamide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1902218", "l": "regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046086", "l": "adenosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902347", "l": "response to strigolactone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905578", "l": "regulation of ERBB3 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019602", "l": "toluene oxidation via 3-hydroxytoluene", "d": ["The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072318", "l": "clathrin coat disassembly", "d": ["The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0002645", "l": "positive regulation of tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1905915", "l": "regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0086073", "l": "bundle of His cell-Purkinje myocyte adhesion involved in cell communication", "d": ["The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0015732", "l": "prostaglandin transport", "d": ["The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060924", "l": "atrial cardiac muscle cell fate commitment", "d": ["The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1903516", "l": "regulation of single strand break repair", "d": ["Any process that modulates the frequency, rate or extent of single strand break repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006297", "l": "nucleotide-excision repair, DNA gap filling", "d": ["Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0034497", "l": "protein localization to phagophore assembly site", "d": ["Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035774", "l": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0106278", "l": "regulation of UDP-N-acetylglucosamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021722", "l": "superior olivary nucleus maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062027", "l": "positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process", "d": ["Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0097307", "l": "response to farnesol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009945", "l": "radial axis specification", "d": ["The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097045", "l": "phosphatidylserine exposure on blood platelet", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0032604", "l": "granulocyte macrophage colony-stimulating factor production", "d": ["The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062172", "l": "lutein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lutein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120084", "l": "endothelial tip cell filopodium assembly", "d": ["The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903218", "l": "regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0019522", "l": "ketogluconate metabolic process", "d": ["The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0033153", "l": "T cell receptor V(D)J recombination", "d": ["The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031444", "l": "slow-twitch skeletal muscle fiber contraction", "d": ["A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140706", "l": "protein-containing complex localization to centriolar satellite", "d": ["A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.490486312819655", "identifiers": [{"i": "GO:0000212", "l": "meiotic spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902870", "l": "negative regulation of amacrine cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106090", "l": "positive regulation of cell adhesion involved in sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0002062", "l": "chondrocyte differentiation", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046780", "l": "symbiont-mediated suppression of host mRNA splicing", "d": ["A process in which a symbiont inhibits or disrupts the splicing of host mRNA, thus interfering with normal host protein production. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039602", "l": "symbiont-mediated suppression of host transcription initiation from RNA polymerase II promoter", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905027", "l": "regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051004", "l": "regulation of lipoprotein lipase activity", "d": ["Any process that modulates the activity of the enzyme lipoprotein lipase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905537", "l": "positive regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090381", "l": "regulation of heart induction", "d": ["Any process that modulates the rate, frequency, or extent of heart induction. 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Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140639", "l": "positive regulation of pyroptosis", "d": ["Any process that increases the frequency, rate or extent of pyroptosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019512", "l": "lactose catabolic process via tagatose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097324", "l": "melanocyte migration", "d": ["The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. 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It contains melanin-filled pigment granules, which give a brown to black appearance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905142", "l": "positive regulation of apical ectodermal ridge formation", "d": ["Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000957", "l": "regulation of cyclodextrin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.829797320023879", "identifiers": [{"i": "GO:0070588", "l": "calcium ion transmembrane transport", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.088320895280148", "identifiers": [{"i": "GO:0022602", "l": "ovulation cycle process", "d": ["A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045642", "l": "positive regulation of basophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of basophil differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007146", "l": "meiotic recombination nodule assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001112", "l": "DNA-templated transcription open complex formation", "d": ["Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0061028", "l": "establishment of endothelial barrier", "d": ["The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061054", "l": "dermatome development", "d": ["The progression of the dermatome over time, from its initial formation to the mature structure. 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The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900137", "l": "negative regulation of chemokine activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900636", "l": "heptadecane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heptadecane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035633", "l": "maintenance of blood-brain barrier", "d": ["Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002018", "l": "renin-angiotensin regulation of aldosterone production", "d": ["The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009452", "l": "7-methylguanosine RNA capping", "d": ["The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0061077", "l": "chaperone-mediated protein folding", "d": ["The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903689", "l": "regulation of wound healing, spreading of epidermal cells", "d": ["Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904550", "l": "response to arachidonic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.741169254015119", "identifiers": [{"i": "GO:1903037", "l": "regulation of leukocyte cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001205", "l": "negative regulation of osteoclast development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1900122", "l": "positive regulation of receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990461", "l": "detoxification of iron ion", "d": ["Any process that reduces or removes the toxicity of iron ion. 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Preventing luteolysis is crucial to maintain pregnancy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904332", "l": "negative regulation of error-prone translesion synthesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001210", "l": "regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902602", "l": "aluminum ion transmembrane transport", "d": ["The process in which an aluminium ion is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046925", "l": "peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine", "d": ["The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031549", "l": "negative regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018949", "l": "m-xylene metabolic process", "d": ["The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:2001053", "l": "regulation of mesenchymal cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904127", "l": "regulation of convergent extension involved in somitogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904233", "l": "negative regulation of aconitate hydratase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900158", "l": "negative regulation of bone mineralization involved in bone maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019387", "l": "methanogenesis, from methanol", "d": ["The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034403", "l": "alignment of 3' and 5' splice sites of mRNA", "d": ["Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140739", "l": "NLRP6 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a NLRP6 inflammasome complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042686", "l": "regulation of cardioblast cell fate specification", "d": ["Any process that mediates the specification of a cell into a cardioblast. 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Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990299", "l": "Bub1-Bub3 complex localization to kinetochore", "d": ["A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905111", "l": "positive regulation of pulmonary blood vessel remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.716864269281565", "identifiers": [{"i": "GO:0035725", "l": "sodium ion transmembrane transport", "d": ["A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0075218", "l": "zoospore encystment on host", "d": ["The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904897", "l": "regulation of hepatic stellate cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048099", "l": "anterior/posterior lineage restriction, imaginal disc", "d": ["Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072391", "l": "phenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140743", "l": "regulation of lncRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of a lncRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0016185", "l": "synaptic vesicle budding from presynaptic endocytic zone membrane", "d": ["Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021810", "l": "neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration", "d": ["Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0045682", "l": "regulation of epidermis development", "d": ["Any process that modulates the frequency, rate or extent of epidermis development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035491", "l": "positive regulation of leukotriene production involved in inflammatory response", "d": ["Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000730", "l": "regulation of termination of RNA polymerase I transcription", "d": ["Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015987", "l": "GTP synthesis coupled proton transport", "d": ["The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901075", "l": "negative regulation of engulfment of apoptotic cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0045581", "l": "negative regulation of T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046544", "l": "development of secondary male sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0140131", "l": "positive regulation of lymphocyte chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0048219", "l": "inter-Golgi cisterna vesicle-mediated transport", "d": ["The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905828", "l": "regulation of prostaglandin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of prostaglandin catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051366", "l": "protein decanoylation", "d": ["The modification of a protein amino acid by formation of an ester or amide with decanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055020", "l": "positive regulation of cardiac muscle fiber development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904466", "l": "positive regulation of matrix metallopeptidase secretion", "d": ["Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904212", "l": "regulation of iodide transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of iodide transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007147", "l": "female meiosis II", "d": ["The cell cycle process in which the second meiotic division occurs in the female germline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900485", "l": "positive regulation of protein targeting to vacuolar membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075046", "l": "positive regulation of formation by symbiont of haustorium for nutrient acquisition from host", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0086021", "l": "SA node cell to atrial cardiac muscle cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.683039265630129", "identifiers": [{"i": "GO:1902903", "l": "regulation of supramolecular fiber organization", "d": ["Any process that modulates the frequency, rate or extent of supramolecular fiber organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035151", "l": "regulation of tube size, open tracheal system", "d": ["Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. 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Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044348", "l": "plant-type cell wall cellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043654", "l": "recognition of apoptotic cell", "d": ["The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0030706", "l": "germarium-derived oocyte differentiation", "d": ["The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051624", "l": "inhibition of norepinephrine uptake", "d": ["Any process that prevents the activation of the directed movement of norepinephrine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904401", "l": "cellular response to Thyroid stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048452", "l": "petal structural organization", "d": ["The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0071230", "l": "cellular response to amino acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001971", "l": "negative regulation of activation of membrane attack complex", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061754", "l": "negative regulation of circulating fibrinogen levels", "d": ["Any process that reduces the quantity of fibrinogen circulating in the bloodstream."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0010762", "l": "regulation of fibroblast migration", "d": ["Any process that modulates the rate, frequency or extent of fibroblast cell migration. 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An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033139", "l": "regulation of peptidyl-serine phosphorylation of STAT protein", "d": ["Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070093", "l": "negative regulation of glucagon secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033400", "l": "trans-zeatin metabolic process", "d": ["The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0110044", "l": "regulation of cell cycle switching, mitotic to meiotic cell cycle", "d": ["Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042750", "l": "hibernation", "d": ["Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. 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The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140723", "l": "patulin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009567", "l": "double fertilization forming a zygote and endosperm", "d": ["Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000353", "l": "formation of quadruple SL/U4/U5/U6 snRNP", "d": ["Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0075296", "l": "positive regulation of ascospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0035304", "l": "regulation of protein dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032210", "l": "regulation of telomere maintenance via telomerase", "d": ["Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061670", "l": "evoked neurotransmitter secretion", "d": ["Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043013", "l": "negative regulation of fusion of sperm to egg plasma membrane", "d": ["Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0044070", "l": "regulation of monoatomic anion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000111", "l": "positive regulation of macrophage apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043536", "l": "positive regulation of blood vessel endothelial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "47.710816582324902", "identifiers": [{"i": "GO:0048523", "l": "negative regulation of cellular process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904965", "l": "regulation of vitamin E biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0007314", "l": "oocyte anterior/posterior axis specification", "d": ["Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042407", "l": "cristae formation", "d": ["The assembly of cristae, the inwards folds of the inner mitochondrial membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0098856", "l": "intestinal lipid absorption", "d": ["Any process in which lipids are taken up from the contents of the intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904534", "l": "negative regulation of telomeric loop disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007158", "l": "neuron cell-cell adhesion", "d": ["The attachment of a neuron to another cell via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0090288", "l": "negative regulation of cellular response to growth factor stimulus", "d": ["Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0097238", "l": "cellular response to methylglyoxal", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061069", "l": "male urethra development", "d": ["The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1903539", "l": "protein localization to postsynaptic membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018402", "l": "protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045683", "l": "negative regulation of epidermis development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035893", "l": "suppression of platelet aggregation in another organism", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060670", "l": "branching involved in labyrinthine layer morphogenesis", "d": ["The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072271", "l": "metanephric short descending thin limb development", "d": ["The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030841", "l": "positive regulation of intermediate filament polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060132", "l": "prolactin secreting cell development", "d": ["The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061278", "l": "epithelial cell migration involved in mesonephric nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0007194", "l": "negative regulation of adenylate cyclase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904188", "l": "negative regulation of transformation of host cell by virus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0086010", "l": "membrane depolarization during action potential", "d": ["The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007496", "l": "anterior midgut development", "d": ["The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061533", "l": "norepinephrine secretion, neurotransmission", "d": ["The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0014003", "l": "oligodendrocyte development", "d": ["The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010773", "l": "meiotic DNA recombinase assembly involved in meiotic gene conversion", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046074", "l": "dTMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0106393", "l": "regulation of palmitic acid catabolic process", "d": ["Any process that modulates the frequency, rate or extent of a palmitic acid catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0015759", "l": "beta-glucoside transport", "d": ["The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022006", "l": "zona limitans intrathalamica formation", "d": ["The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045197", "l": "establishment or maintenance of epithelial cell apical/basal polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900457", "l": "regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905026", "l": "positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.960002279600147", "identifiers": [{"i": "GO:0051261", "l": "protein depolymerization", "d": ["The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. 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Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097389", "l": "chemokine (C-C motif) ligand 21 production", "d": ["The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071724", "l": "response to diacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010304", "l": "PSII associated light-harvesting complex II catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061592", "l": "phosphatidylserine exposure on osteoblast involved in bone mineralization", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071996", "l": "glutathione transmembrane import into vacuole", "d": ["The directed movement of glutathione into the vacuole across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009859", "l": "pollen hydration", "d": ["The process in which water is taken up by pollen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0039514", "l": "symbiont-mediated suppression of host JAK-STAT cascade", "d": ["A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901596", "l": "response to reversine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048891", "l": "lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0141067", "l": "intracellular nitrogen homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905367", "l": "positive regulation of intralumenal vesicle formation", "d": ["Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903062", "l": "regulation of reverse cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of reverse cholesterol transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902274", "l": "positive regulation of (R)-carnitine transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070318", "l": "positive regulation of G0 to G1 transition", "d": ["A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0032988", "l": "protein-RNA complex disassembly", "d": ["The disaggregation of a protein-RNA complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905696", "l": "regulation of polysome binding", "d": ["Any process that modulates the frequency, rate or extent of polysome binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0042780", "l": "tRNA 3'-end processing", "d": ["The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033498", "l": "galactose catabolic process via D-galactonate", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.58151099991538", "identifiers": [{"i": "GO:0071345", "l": "cellular response to cytokine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051823", "l": "regulation of synapse structural plasticity", "d": ["Any process that modulates the frequency, rate or extent of synapse structural plasticity. 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Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:2000904", "l": "regulation of starch metabolic process", "d": ["Any process that modulates the frequency, rate or extent of starch metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000764", "l": "positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070811", "l": "glycerol-2-phosphate transmembrane transport", "d": ["The process in which glycerol-2-phosphate is transported across a membrane. 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The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010656", "l": "negative regulation of muscle cell apoptotic process", "d": ["Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:0050767", "l": "regulation of neurogenesis", "d": ["Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098958", "l": "retrograde axonal transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140209", "l": "zinc ion import into endoplasmic reticulum", "d": ["The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900828", "l": "D-tyrosine metabolic process", "d": ["The chemical reactions and pathways involving D-tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990705", "l": "cholangiocyte proliferation", "d": ["The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. 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The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. 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DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062231", "l": "positive regulation of larval somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of larval somatic muscle development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0002343", "l": "peripheral B cell selection", "d": ["Any B cell selection process that occurs in the periphery."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071816", "l": "tail-anchored membrane protein insertion into ER membrane", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014905", "l": "myoblast fusion involved in skeletal muscle regeneration", "d": ["A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900743", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to pH", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0031392", "l": "regulation of prostaglandin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002564", "l": "alternate splicing of immunoglobulin genes", "d": ["The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905136", "l": "dethiobiotin import across plasma membrane", "d": ["The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0042790", "l": "nucleolar large rRNA transcription by RNA polymerase I", "d": ["The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075278", "l": "negative regulation of telium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0002776", "l": "antimicrobial peptide secretion", "d": ["The regulated release of an antimicrobial peptide from a cell or a tissue. 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It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048312", "l": "intracellular distribution of mitochondria", "d": ["Any process that establishes the spatial arrangement of mitochondria within the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905583", "l": "cellular response to mannose", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.410865998300608", "identifiers": [{"i": "GO:0051169", "l": "nuclear transport", "d": ["The directed movement of substances into, out of, or within the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.410865998300608", "identifiers": [{"i": "GO:0042552", "l": "myelination", "d": ["The process in which myelin sheaths are formed and maintained around neurons. 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The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045915", "l": "positive regulation of catecholamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904441", "l": "regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904234", "l": "positive regulation of aconitate hydratase activity", "d": ["Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045600", "l": "positive regulation of fat cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of adipocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085034", "l": "symbiont-mediated suppression of host NF-kappaB cascade", "d": ["A process in which a symbiont interferes with, inhibits or disrupts an NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0048320", "l": "axial mesoderm formation", "d": ["The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046014", "l": "negative regulation of T cell homeostatic proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002734", "l": "negative regulation of myeloid dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051977", "l": "lysophospholipid transport", "d": ["The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Transfer RNAs (tRNA) genes, as well as some other non-coding RNAs, are transcribed by RNA polymerase III."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0006551", "l": "leucine metabolic process", "d": ["The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060802", "l": "epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification", "d": ["Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150020", "l": "basal dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0021984", "l": "adenohypophysis development", "d": ["The progression of the adenohypophysis over time from its initial formation until its mature state. 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It secretes a variety of hormones and its function is regulated by the hypothalamus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018321", "l": "protein glucuronylation", "d": ["The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0002778", "l": "antibacterial peptide production", "d": ["The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0042053", "l": "regulation of dopamine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0071559", "l": "response to transforming growth factor beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000387", "l": "regulation of antral ovarian follicle growth", "d": ["Any process that modulates the frequency, rate or extent of antral ovarian follicle growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0014901", "l": "satellite cell activation involved in skeletal muscle regeneration", "d": ["The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032829", "l": "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0046440", "l": "L-lysine metabolic process", "d": ["The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018393", "l": "internal peptidyl-lysine acetylation", "d": ["The addition of an acetyl group to a non-terminal lysine residue in a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034372", "l": "very-low-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032825", "l": "positive regulation of natural killer cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0038016", "l": "insulin receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002110", "l": "cotranscriptional mitochondrial rRNA nucleotide insertion", "d": ["The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905312", "l": "positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000678", "l": "negative regulation of transcription regulatory region DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031173", "l": "otolith mineralization completed early in development", "d": ["The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.432745995597372", "identifiers": [{"i": "GO:0009072", "l": "aromatic amino acid metabolic process", "d": ["The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032345", "l": "negative regulation of aldosterone metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905365", "l": "regulation of intralumenal vesicle formation", "d": ["Any process that modulates the frequency, rate or extent of intralumenal vesicle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007138", "l": "meiotic anaphase II", "d": ["The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046621", "l": "negative regulation of organ growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0043633", "l": "polyadenylation-dependent RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032772", "l": "negative regulation of tyrosinase activity", "d": ["Any process that stops or reduces the activity of a tyrosinase enzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009203", "l": "ribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018339", "l": "peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid", "d": ["The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904368", "l": "regulation of sclerenchyma cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033189", "l": "response to vitamin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070807", "l": "positive regulation of phialide development", "d": ["Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904878", "l": "negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035699", "l": "T-helper 17 cell extravasation", "d": ["The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033386", "l": "geranylgeranyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1905216", "l": "positive regulation of RNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of RNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051218", "l": "tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)", "d": ["The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905621", "l": "positive regulation of alpha-(1->3)-fucosyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000727", "l": "double-strand break repair via break-induced replication", "d": ["The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900556", "l": "emericellamide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellamide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0007160", "l": "cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904611", "l": "cellular response to 3,3',4,4',5-pentachlorobiphenyl", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090392", "l": "sepal giant cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. 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Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048911", "l": "efferent axon development in anterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. 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Peptidoglycan is a bacterial cell wall macromolecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021512", "l": "spinal cord anterior/posterior patterning", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018939", "l": "n-octane metabolic process", "d": ["The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. 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In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031441", "l": "negative regulation of mRNA 3'-end processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140479", "l": "ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase", "d": ["A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140875", "l": "PR-toxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0022608", "l": "multicellular organism adhesion", "d": ["The attachment of a multicellular organism to a substrate or other organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990771", "l": "clathrin-dependent extracellular exosome endocytosis", "d": ["The clathrin-mediated endocytosis of an extracellular exosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018978", "l": "anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process", "d": ["The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0036444", "l": "calcium import into the mitochondrion", "d": ["A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001198", "l": "regulation of dendritic cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097195", "l": "pilomotor reflex", "d": ["The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048254", "l": "snoRNA localization", "d": ["Any process in which small nucleolar RNA is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075229", "l": "negative regulation of encysted zoospore germination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002842", "l": "positive regulation of T cell mediated immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002093", "l": "auditory receptor cell morphogenesis", "d": ["Any process that alters the size or shape of an auditory receptor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061285", "l": "mesonephric capsule development", "d": ["The progression of the mesonephric capsule over time, from its formation to the mature structure. 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A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0090679", "l": "cell differentiation involved in phenotypic switching", "d": ["A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036116", "l": "long-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. 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One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, some viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098819", "l": "depolarization of postsynaptic membrane", "d": ["A process that depolarizes a postsynaptic membrane relative to its resting potential. 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Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060100", "l": "positive regulation of phagocytosis, engulfment", "d": ["Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0039702", "l": "viral budding via host ESCRT complex", "d": ["Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000336", "l": "negative regulation of endothelial microparticle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003293", "l": "heart valve cell differentiation", "d": ["The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.766206828801351", "identifiers": [{"i": "GO:0006935", "l": "chemotaxis", "d": ["The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0036466", "l": "synaptic vesicle recycling via endosome", "d": ["Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0060209", "l": "estrus", "d": ["The estrous cycle phase in which a female is sexually receptive."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:2001088", "l": "trisaccharide transport", "d": ["The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072062", "l": "proximal convoluted tubule segment 1 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904057", "l": "negative regulation of sensory perception of pain", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042128", "l": "nitrate assimilation", "d": ["The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070460", "l": "thyroid-stimulating hormone secretion", "d": ["The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0001979", "l": "regulation of systemic arterial blood pressure by chemoreceptor signaling", "d": ["The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042884", "l": "microcin transport", "d": ["The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0032366", "l": "intracellular sterol transport", "d": ["The directed movement of sterols within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902971", "l": "mitotic DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding involved in mitotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905601", "l": "negative regulation of receptor-mediated endocytosis involved in cholesterol transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002362", "l": "CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903752", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.653457143972261", "identifiers": [{"i": "GO:0015947", "l": "methane metabolic process", "d": ["The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. 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They can be classed as slow, intermediate/fast or fast."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035752", "l": "lysosomal lumen pH elevation", "d": ["Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031222", "l": "arabinan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0002244", "l": "hematopoietic progenitor cell differentiation", "d": ["The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010031", "l": "circumnutation", "d": ["The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0140271", "l": "hexose import across plasma membrane", "d": ["The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0061157", "l": "mRNA destabilization", "d": ["Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. 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A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0002864", "l": "regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902354", "l": "blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment", "d": ["Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0098725", "l": "symmetric cell division", "d": ["Cell division in which both daughter cells are of the same type."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0150172", "l": "regulation of phosphatidylcholine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0070314", "l": "G1 to G0 transition", "d": ["A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0009620", "l": "response to fungus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003276", "l": "apoptotic process involved in heart valve morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of a heart valve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006003", "l": "fructose 2,6-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving fructose 2,6-bisphosphate. 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It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072703", "l": "cellular response to methyl methanesulfonate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035493", "l": "SNARE complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0030917", "l": "midbrain-hindbrain boundary development", "d": ["The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033621", "l": "nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070452", "l": "positive regulation of ergosterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0086002", "l": "cardiac muscle cell action potential involved in contraction", "d": ["An action potential that occurs in a cardiac muscle cell and is involved in its contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0030185", "l": "nitric oxide transport", "d": ["The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048803", "l": "imaginal disc-derived male genitalia morphogenesis", "d": ["The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002266", "l": "follicular dendritic cell activation", "d": ["A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:2000136", "l": "regulation of cell proliferation involved in heart morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036152", "l": "phosphatidylethanolamine acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061911", "l": "amphisome-lysosome fusion", "d": ["The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046495", "l": "nicotinamide riboside metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0097341", "l": "zymogen inhibition", "d": ["Any process that prevents the proteolytic processing of an inactive enzyme to an active form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000097", "l": "sulfur amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904022", "l": "positive regulation of G protein-coupled receptor internalization", "d": ["Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0019666", "l": "nitrogenous compound fermentation", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072667", "l": "maintenance of protein location in vacuole", "d": ["Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048847", "l": "adenohypophysis formation", "d": ["The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006432", "l": "phenylalanyl-tRNA aminoacylation", "d": ["The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.180713427975022", "identifiers": [{"i": "GO:0075260", "l": "regulation of spore-bearing organ development", "d": ["Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001869", "l": "negative regulation of complement activation, lectin pathway", "d": ["Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0002237", "l": "response to molecule of bacterial origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060381", "l": "positive regulation of single-stranded telomeric DNA binding", "d": ["Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031536", "l": "positive regulation of exit from mitosis", "d": ["Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006283", "l": "transcription-coupled nucleotide-excision repair", "d": ["The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048903", "l": "anterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090026", "l": "positive regulation of monocyte chemotaxis", "d": ["Any process that increases the frequency, rate, or extent of monocyte chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033346", "l": "asparagine catabolic process via 2-oxosuccinamate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0010998", "l": "regulation of translational initiation by eIF2 alpha phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0075109", "l": "symbiont-mediated perturbation of host receptor-mediated signal transduction", "d": ["A process by which a symbiont alters or subverts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032760", "l": "positive regulation of tumor necrosis factor production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:0043487", "l": "regulation of RNA stability", "d": ["Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021762", "l": "substantia nigra development", "d": ["The progression of the substantia nigra over time from its initial formation until its mature state. 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An example of this process is analia morphogenesis in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0043161", "l": "proteasome-mediated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0015860", "l": "purine nucleoside transmembrane transport", "d": ["The process in which a purine nucleoside is transported across a membrane. 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The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905366", "l": "negative regulation of intralumenal vesicle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090714", "l": "innate immunity memory response", "d": ["An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0006012", "l": "galactose metabolic process", "d": ["The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098730", "l": "male germline stem cell symmetric division", "d": ["The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. 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The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032012", "l": "regulation of ARF protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of ARF protein signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001249", "l": "negative regulation of ammonia assimilation cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1902991", "l": "regulation of amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.630404611420033", "identifiers": [{"i": "GO:0009893", "l": "positive regulation of metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019240", "l": "citrulline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904571", "l": "positive regulation of selenocysteine incorporation", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.443722533031213", "identifiers": [{"i": "GO:0043067", "l": "regulation of programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0098885", "l": "modification of postsynaptic actin cytoskeleton", "d": ["Any process that modifies the structure of a postsynaptic actin cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022017", "l": "neuroblast division in pallium", "d": ["The division of neuroblasts in the pallium. 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The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. 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D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.133503718432891", "identifiers": [{"i": "GO:0040012", "l": "regulation of locomotion", "d": ["Any process that modulates the frequency, rate or extent of locomotion of a cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051884", "l": "regulation of timing of anagen", "d": ["Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0033375", "l": "protease localization to T cell secretory granule", "d": ["Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902184", "l": "negative regulation of shoot apical meristem development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051414", "l": "response to cortisol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0033371", "l": "T cell secretory granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. 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A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0002834", "l": "regulation of response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of a response to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032837", "l": "distributive segregation", "d": ["The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905093", "l": "cellular response to diosgenin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902148", "l": "positive regulation of response to cytokinesis checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0110110", "l": "positive regulation of animal organ morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0017148", "l": "negative regulation of translation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902057", "l": "(25S)-Delta(4)-dafachronate metabolic process", "d": ["The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0006636", "l": "unsaturated fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904151", "l": "positive regulation of microglial cell mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010964", "l": "regulation of regulatory ncRNA-mediated heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001033", "l": "negative regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072592", "l": "oxygen metabolic process", "d": ["The chemical reactions and pathways involving diatomic oxygen (O2)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904189", "l": "positive regulation of transformation of host cell by virus", "d": ["Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900982", "l": "positive regulation of phenazine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0030318", "l": "melanocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a melanocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061530", "l": "aspartate secretion, neurotransmission", "d": ["The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007542", "l": "primary sex determination, germ-line", "d": ["The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021506", "l": "anterior neuropore closure", "d": ["The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010732", "l": "regulation of protein glutathionylation", "d": ["Any process that modulates the rate, frequency, or extent of protein glutathionylation. 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The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0006677", "l": "glycosylceramide metabolic process", "d": ["The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061067", "l": "negative regulation of dauer larval development", "d": ["Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010589", "l": "leaf proximal/distal pattern formation", "d": ["The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033272", "l": "myo-inositol hexakisphosphate transport", "d": ["The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0046513", "l": "ceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046117", "l": "queuosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044080", "l": "symbiont-mediated perturbation of host cGMP-mediated signal transduction", "d": ["A process in which a symbiont alters or subverts a cGMP-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061375", "l": "mammillotectal axonal tract development", "d": ["The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032364", "l": "intracellular oxygen homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070660", "l": "inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration", "d": ["Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0002644", "l": "negative regulation of tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003275", "l": "apoptotic process involved in outflow tract morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0062100", "l": "positive regulation of programmed necrotic cell death", "d": ["Any process that increases the frequency, rate or extent of programmed necrotic cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052025", "l": "symbiont-mediated perturbation of host cell endomembrane system", "d": ["The process in which an organism effects a change that impairs the structure or function of the host endomembrane system. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120309", "l": "cilium attachment to cell body", "d": ["A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007352", "l": "zygotic specification of dorsal/ventral axis", "d": ["The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010775", "l": "meiotic strand invasion involved in meiotic gene conversion", "d": ["The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0002717", "l": "positive regulation of natural killer cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990784", "l": "response to dsDNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097391", "l": "chemokine (C-X-C motif) ligand 13 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904711", "l": "regulation of Wnt-Frizzled-LRP5/6 complex assembly", "d": ["Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045854", "l": "positive regulation of bicoid mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0045230", "l": "capsule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048084", "l": "positive regulation of adult chitin-containing cuticle pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033031", "l": "positive regulation of neutrophil apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045498", "l": "sex comb development", "d": ["The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071448", "l": "cellular response to alkyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.683527111924249", "identifiers": [{"i": "GO:0007565", "l": "female pregnancy", "d": ["The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030919", "l": "peptidyl-serine O-acetylation", "d": ["The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905670", "l": "TORC2 complex disassembly", "d": ["The disaggregation of a TORC2 complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0001762", "l": "beta-alanine transport", "d": ["The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903379", "l": "regulation of mitotic chromosome condensation", "d": ["Any process that modulates the frequency, rate or extent of mitotic chromosome condensation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900664", "l": "regulation of emodin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emodin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0007447", "l": "imaginal disc pattern formation", "d": ["The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070392", "l": "detection of lipoteichoic acid", "d": ["The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062110", "l": "negative regulation of DNA recombinase disassembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.211993186354135", "identifiers": [{"i": "GO:0016053", "l": "organic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0019094", "l": "pole plasm mRNA localization", "d": ["Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031556", "l": "transcriptional attenuation by ribosome", "d": ["A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900926", "l": "regulation of L-threonine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-threonine import into cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031115", "l": "negative regulation of microtubule polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030539", "l": "male genitalia development", "d": ["The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120214", "l": "negative regulation of histidine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009717", "l": "isoflavonoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019546", "l": "arginine deiminase pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051889", "l": "negative regulation of timing of exogen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071693", "l": "protein transport within extracellular region", "d": ["The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009666", "l": "plastid outer membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.504650478785891", "identifiers": [{"i": "GO:0002688", "l": "regulation of leukocyte chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046132", "l": "pyrimidine ribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070301", "l": "cellular response to hydrogen peroxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "50.004653157243716", "identifiers": [{"i": "GO:0046717", "l": "acid secretion", "d": ["The controlled release of acid by a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:1902904", "l": "negative regulation of supramolecular fiber organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.819794207913709", "identifiers": [{"i": "GO:0050776", "l": "regulation of immune response", "d": ["Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031539", "l": "positive regulation of anthocyanin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010082", "l": "regulation of root meristem growth", "d": ["Any process involved in maintaining the size and shape of a root meristem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006009", "l": "glucose 1-phosphate phosphorylation", "d": ["The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150103", "l": "reactive gliosis", "d": ["A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901443", "l": "negative regulation of response to furfural", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090453", "l": "aspartate transmembrane import into vacuole", "d": ["The directed movement of aspartate into the vacuole across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990045", "l": "sclerotium development", "d": ["The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032727", "l": "positive regulation of interferon-alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-alpha production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002117", "l": "amphibian larval development", "d": ["The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001694", "l": "histamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905353", "l": "ciliary transition fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060582", "l": "cell fate determination involved in pattern specification", "d": ["A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0009608", "l": "response to symbiont", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032057", "l": "negative regulation of translational initiation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904551", "l": "cellular response to arachidonic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903843", "l": "cellular response to arsenite ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120331", "l": "endothelial tube formation", "d": ["The developmental process pertaining to the initial formation of an endothelial tube."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903544", "l": "response to butyrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2001225", "l": "regulation of chloride transport", "d": ["Any process that modulates the frequency, rate or extent of chloride transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097717", "l": "copper ion transport across blood-cerebrospinal fluid barrier", "d": ["The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110005", "l": "positive regulation of tRNA C5-cytosine methylation", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901780", "l": "pentalenolactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentalenolactone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061573", "l": "actin filament bundle retrograde transport", "d": ["A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0002839", "l": "positive regulation of immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098045", "l": "virus baseplate assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus baseplate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900265", "l": "regulation of substance P receptor binding", "d": ["Any process that modulates the frequency, rate or extent of substance P receptor binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045234", "l": "protein palmitoleylation", "d": ["The covalent attachment of a palmitoleyl group to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044320", "l": "cellular response to leptin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032656", "l": "regulation of interleukin-13 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-13 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903648", "l": "positive regulation of chlorophyll catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904793", "l": "regulation of euchromatin binding", "d": ["Any process that modulates the frequency, rate or extent of euchromatin binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904502", "l": "regulation of lipophagy", "d": ["Any process that modulates the frequency, rate or extent of lipophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.574257682819926", "identifiers": [{"i": "GO:0051094", "l": "positive regulation of developmental process", "d": ["Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061962", "l": "negative regulation of heme oxygenase activity", "d": ["Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.315929082021214", "identifiers": [{"i": "GO:0016068", "l": "type I hypersensitivity", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060297", "l": "regulation of sarcomere organization", "d": ["Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0032627", "l": "interleukin-23 production", "d": ["The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0050884", "l": "neuromuscular process controlling posture", "d": ["Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0014015", "l": "positive regulation of gliogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900443", "l": "regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021698", "l": "cerebellar cortex structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035920", "l": "negative regulation of high voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0018126", "l": "protein hydroxylation", "d": ["The addition of a hydroxy group to a protein amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0060811", "l": "intracellular mRNA localization involved in anterior/posterior axis specification", "d": ["Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904523", "l": "regulation of DNA amplification", "d": ["Any process that modulates the frequency, rate or extent of DNA amplification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0099518", "l": "vesicle cytoskeletal trafficking", "d": ["The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009098", "l": "leucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014863", "l": "detection of inactivity", "d": ["The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042796", "l": "snRNA transcription by RNA polymerase III", "d": ["The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044578", "l": "butyryl-CoA biosynthetic process", "d": ["The chemical reactions and pathway resulting in the formation of butyryl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003100", "l": "regulation of systemic arterial blood pressure by endothelin", "d": ["The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902003", "l": "regulation of amyloid-beta formation", "d": ["Any process that modulates the frequency, rate or extent of amyloid-beta formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000954", "l": "methionine catabolic process to 3-methylthiopropanoate", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090338", "l": "positive regulation of formin-nucleated actin cable assembly", "d": ["Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0019539", "l": "hydroxymate-containing siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019251", "l": "anaerobic cobalamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051464", "l": "positive regulation of cortisol secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002072", "l": "optic cup morphogenesis involved in camera-type eye development", "d": ["The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045929", "l": "positive regulation of juvenile hormone metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.58909006025462", "identifiers": [{"i": "GO:0042278", "l": "purine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990625", "l": "negative regulation of cytoplasmic translational initiation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042268", "l": "regulation of cytolysis", "d": ["Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120058", "l": "positive regulation of small intestinal transit", "d": ["Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043579", "l": "elaioplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021518", "l": "spinal cord commissural neuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010060", "l": "negative regulation of atrichoblast fate specification", "d": ["Any process that suppresses atrichoblast fate specification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.58909006025462", "identifiers": [{"i": "GO:0032369", "l": "negative regulation of lipid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000482", "l": "maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0007282", "l": "cystoblast division", "d": ["Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904992", "l": "positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009589", "l": "detection of UV", "d": ["The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. 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By blocking tetherin activity, many viruses circumvent its antiviral effects."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140964", "l": "intracellular auxin homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of auxin within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060439", "l": "trachea morphogenesis", "d": ["The process in which a trachea is generated and organized. 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The outflow tract is the portion of the heart through which blood flows into the arteries."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "48.677767579130645", "identifiers": [{"i": "GO:0048522", "l": "positive regulation of cellular process", "d": ["Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0017010", "l": "protein-phycourobilin linkage", "d": ["The linkage of the chromophore phycourobilin to phycoerythrins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002345", "l": "peripheral B cell receptor editing", "d": ["The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035436", "l": "triose phosphate transmembrane transport", "d": ["The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. 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This process pertains to the initial formation of a structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001209", "l": "positive regulation of transcription elongation by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003204", "l": "cardiac skeleton development", "d": ["The progression of the cardiac skeleton over time, from its formation to the mature structure. 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The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. 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The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030543", "l": "2-micrometer plasmid partitioning", "d": ["The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0071071", "l": "regulation of phospholipid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0010227", "l": "floral organ abscission", "d": ["The controlled shedding of floral organs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061480", "l": "response to asparaginase", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0036161", "l": "calcitonin secretion", "d": ["The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0002401", "l": "tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002124", "l": "territorial aggressive behavior", "d": ["Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051614", "l": "inhibition of serotonin uptake", "d": ["Any process that prevents the activation of the directed movement of serotonin into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903621", "l": "protein localization to photoreceptor connecting cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.490486312819655", "identifiers": [{"i": "GO:0070231", "l": "T cell apoptotic process", "d": ["Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120324", "l": "procyclogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0014742", "l": "positive regulation of muscle hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of muscle hypertrophy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071245", "l": "cellular response to carbon monoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0106288", "l": "regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039536", "l": "negative regulation of RIG-I signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0039674", "l": "exit of virus from host cell nucleus", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0001881", "l": "receptor recycling", "d": ["The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. 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Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900288", "l": "regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009801", "l": "cinnamic acid ester metabolic process", "d": ["The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1990736", "l": "regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071412", "l": "cellular response to genistein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902698", "l": "pentose catabolic process to butyrate", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to butyrate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043496", "l": "regulation of protein homodimerization activity", "d": ["Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990557", "l": "mitochondrial sulfate transmembrane transport", "d": ["The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.156270827921489", "identifiers": [{"i": "GO:0014706", "l": "striated muscle tissue development", "d": ["The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. 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The fusion of cardiac cells is very rare and can only form binucleate cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021725", "l": "superior raphe nucleus development", "d": ["The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903026", "l": "negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905116", "l": "positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051114", "l": "peptidyl-histidine uridylylation", "d": ["The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075221", "l": "negative regulation of zoospore encystment on host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035322", "l": "mesenchymal cell migration involved in limb bud formation", "d": ["The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000309", "l": "positive regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1900180", "l": "regulation of protein localization to nucleus", "d": ["Any process that modulates the frequency, rate or extent of protein localization to nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0001773", "l": "myeloid dendritic cell activation", "d": ["The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.584647820776595", "identifiers": [{"i": "GO:0160043", "l": "catecholamine secretion, neurotransmission", "d": ["The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072242", "l": "metanephric DCT cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901055", "l": "trimethylenediamine metabolic process", "d": ["The chemical reactions and pathways involving trimethylenediamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061555", "l": "ganglion structural organization", "d": ["The process that contributes to creating the structural organization of a ganglion. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1990505", "l": "mitotic DNA replication maintenance of fidelity", "d": ["Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0072038", "l": "mesenchymal stem cell maintenance involved in nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. 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AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001213", "l": "negative regulation of vasculogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010754", "l": "negative regulation of cGMP-mediated signaling", "d": ["Any process that decreases the rate, frequency or extent of cGMP-mediated signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045070", "l": "positive regulation of viral genome replication", "d": ["Any process that activates or increases the frequency, rate or extent of viral genome replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044349", "l": "DNA excision", "d": ["The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.868301077661471", "identifiers": [{"i": "GO:0017157", "l": "regulation of exocytosis", "d": ["Any process that modulates the frequency, rate or extent of exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003193", "l": "pulmonary valve formation", "d": ["The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. 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Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072036", "l": "mesenchymal to epithelial transition involved in renal vesicle formation", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019276", "l": "UDP-N-acetylgalactosamine metabolic process", "d": ["The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0003313", "l": "heart rudiment development", "d": ["The progression of the heart rudiment over time, from its initial formation to the mature structure. 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An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.323683528673989", "identifiers": [{"i": "GO:0001667", "l": "ameboidal-type cell migration", "d": ["Cell migration that is accomplished by extension and retraction of a pseudopodium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1904892", "l": "regulation of receptor signaling pathway via STAT", "d": ["Any process that modulates the frequency, rate or extent of receptor signaling via STAT."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050902", "l": "leukocyte adhesive activation", "d": ["The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904101", "l": "response to acadesine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0070585", "l": "protein localization to mitochondrion", "d": ["A process in which a protein is transported to, or maintained in, a location within the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000604", "l": "negative regulation of secondary growth", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014858", "l": "positive regulation of skeletal muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0002716", "l": "negative regulation of natural killer cell mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045630", "l": "positive regulation of T-helper 2 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048775", "l": "regulation of leucophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of leucophore differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001076", "l": "positive regulation of metanephric ureteric bud development", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002530", "l": "regulation of systemic arterial blood pressure involved in acute-phase response", "d": ["Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. 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It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036372", "l": "opsin transport", "d": ["The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060917", "l": "regulation of (1->6)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003189", "l": "aortic valve formation", "d": ["The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. 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The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042725", "l": "thiamine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900840", "l": "regulation of helvolic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061610", "l": "glycerol to glycerone phosphate metabolic process", "d": ["The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0022401", "l": "negative adaptation of signaling pathway", "d": ["The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "17.246812607119921", "identifiers": [{"i": "GO:1901564", "l": "organonitrogen compound metabolic process", "d": ["The chemical reactions and pathways involving organonitrogen compound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0050934", "l": "late stripe melanocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). 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upon determination, the cell fate cannot be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044655", "l": "phagosome reneutralization", "d": ["Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905012", "l": "regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035159", "l": "regulation of tube length, open tracheal system", "d": ["Ensuring that a tube in an open tracheal system is of the correct length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009909", "l": "regulation of flower development", "d": ["Any process that modulates the frequency, rate or extent of flower development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018219", "l": "peptidyl-cysteine S-acetylation", "d": ["The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0002843", "l": "regulation of tolerance induction to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021950", "l": "chemorepulsion involved in precerebellar neuron migration", "d": ["The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0110040", "l": "nematode pharynx morphogenesis", "d": ["The process in which the anatomical structures of the nematode pharynx are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1903189", "l": "glyoxal metabolic process", "d": ["The chemical reactions and pathways involving glyoxal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902723", "l": "negative regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140430", "l": "positive regulation of chromosome passenger complex localization to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106028", "l": "neuron projection retraction", "d": ["The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.875378082774276", "identifiers": [{"i": "GO:0043470", "l": "regulation of carbohydrate catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034031", "l": "ribonucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0036336", "l": "dendritic cell migration", "d": ["The movement of a dendritic cell within or between different tissues and organs of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106154", "l": "perithecium formation", "d": ["The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901190", "l": "regulation of formation of translation initiation ternary complex", "d": ["Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0140273", "l": "repair of mitotic kinetochore microtubule attachment defect", "d": ["The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009946", "l": "proximal/distal axis specification", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis. 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In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0000103", "l": "sulfate assimilation", "d": ["The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0048881", "l": "mechanosensory lateral line system development", "d": ["The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045578", "l": "negative regulation of B cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110098", "l": "positive regulation of calcium import into the mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080027", "l": "response to herbivore", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141009", "l": "piRNA-mediated retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a piRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090194", "l": "negative regulation of glomerulus development", "d": ["Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. 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Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.929890650779797", "identifiers": [{"i": "GO:1905952", "l": "regulation of lipid localization", "d": ["Any process that modulates the frequency, rate or extent of lipid localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045895", "l": "positive regulation of mating-type specific transcription, DNA-templated", "d": ["Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900841", "l": "negative regulation of helvolic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902835", "l": "negative regulation of proline import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070275", "l": "aerobic ammonia oxidation to nitrite via pyruvic oxime", "d": ["The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141141", "l": "evasion of symbiont recognition by host pattern recognition receptor", "d": ["A process by which a symbiont avoids recognition by host's innate immune response by altering or concealing a conserved molecule recognized by the host's cell surface and intracellular pattern recognition receptors, including Toll-like and NOD-like receptors. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000025", "l": "regulation of leaf formation", "d": ["Any process that modulates the frequency, rate or extent of leaf formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990550", "l": "mitochondrial alpha-ketoglutarate transmembrane transport", "d": ["The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042404", "l": "thyroid hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090516", "l": "L-serine transmembrane import into vacuole", "d": ["The directed movement of L-serine into the vacuole across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003004", "l": "follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage", "d": ["The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120059", "l": "negative regulation of small intestinal transit", "d": ["Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000246", "l": "positive regulation of FtsZ-dependent cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019521", "l": "D-gluconate metabolic process", "d": ["The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901917", "l": "regulation of exoribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exoribonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000728", "l": "regulation of mRNA export from nucleus in response to heat stress", "d": ["Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0050856", "l": "regulation of T cell receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141007", "l": "siRNA-mediated retrotransposon silencing by heterochromatin formation", "d": ["A retrotransposon silencing mechanism in which a siRNA triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032741", "l": "positive regulation of interleukin-18 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-18 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0097017", "l": "renal protein absorption", "d": ["A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0039709", "l": "cytoplasmic capsid assembly", "d": ["The assembly of a virus capsid that occurs in the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007534", "l": "gene conversion at mating-type locus", "d": ["The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902865", "l": "positive regulation of embryonic camera-type eye development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905797", "l": "negative regulation of intraciliary anterograde transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071051", "l": "polyadenylation-dependent snoRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006068", "l": "ethanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060093", "l": "negative regulation of synaptic transmission, glycinergic", "d": ["Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. 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In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090360", "l": "platelet-derived growth factor production", "d": ["The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048825", "l": "cotyledon development", "d": ["The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. 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The cotyledons may appear above ground and show photosynthetic activity in the seedling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048073", "l": "regulation of eye pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903896", "l": "positive regulation of IRE1-mediated unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009960", "l": "endosperm development", "d": ["The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0015887", "l": "pantothenate transmembrane transport", "d": ["The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180026", "l": "mitochondrial small ribosomal subunit assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial small ribosomal subunit."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0071422", "l": "succinate transmembrane transport", "d": ["The process in which succinate is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:1990173", "l": "protein localization to nucleoplasm", "d": ["A process in which a protein is transported to, or maintained in, a location within the nucleoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0031134", "l": "sister chromatid biorientation", "d": ["The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.774074961591239", "identifiers": [{"i": "GO:0042742", "l": "defense response to bacterium", "d": ["Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0002515", "l": "B cell anergy", "d": ["Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000089", "l": "positive regulation of mesonephric glomerulus development", "d": ["Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905633", "l": "establishment of protein localization to euchromatin", "d": ["The directed movement of a protein to a specific location in an euchromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000952", "l": "negative regulation of xyloglucan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040010", "l": "positive regulation of growth rate", "d": ["Any process that increases the rate of growth of all or part of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.432745995597372", "identifiers": [{"i": "GO:0002704", "l": "negative regulation of leukocyte mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097303", "l": "lipoprotein biosynthetic process via N-acyl transfer", "d": ["The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0044501", "l": "perturbation of signal transduction in another organism", "d": ["The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075224", "l": "positive regulation of sporangium germination", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0072564", "l": "blood microparticle formation", "d": ["The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0000965", "l": "mitochondrial RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106212", "l": "centromere detachment from spindle pole body involved in meiotic chromosome organization", "d": ["The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0042868", "l": "antisense RNA metabolic process", "d": ["The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904780", "l": "negative regulation of protein localization to centrosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0050764", "l": "regulation of phagocytosis", "d": ["Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120140", "l": "negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072581", "l": "protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine", "d": ["The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000835", "l": "negative regulation of androgen secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036245", "l": "cellular response to menadione", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0046865", "l": "terpenoid transport", "d": ["The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002041", "l": "intussusceptive angiogenesis", "d": ["The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000102", "l": "negative regulation of mammary stem cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140976", "l": "defense response against perturbation of plasma membrane integrity", "d": ["The cellular processes and signaling pathways by which a cell responds to disruption of the integrity of its plasma membrane by another organism. Some toxins produced by other organisms can form pores in membranes, or affect the membrane permeability."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903199", "l": "negative regulation of L-dopa decarboxylase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021906", "l": "hindbrain-spinal cord boundary formation", "d": ["The process whose specific outcome is the formation of the hindbrain-spinal cord boundary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0051762", "l": "sesquiterpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010199", "l": "organ boundary specification between lateral organs and the meristem", "d": ["The process in which boundaries between lateral organs and the meristem is established and maintained."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021600", "l": "abducens nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the abducens nerve. 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A major component of the cell wall outer membrane of Gram-negative bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048354", "l": "mucilage biosynthetic process involved in seed coat development", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905092", "l": "response to diosgenin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902757", "l": "bis(molybdopterin guanine dinucleotide)molybdenum metabolic process", "d": ["The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010668", "l": "ectodermal cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0007632", "l": "visual behavior", "d": ["The behavior of an organism in response to a visual stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902609", "l": "(R)-2-hydroxy-alpha-linolenic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140588", "l": "chromatin looping", "d": ["A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0032868", "l": "response to insulin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. 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The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0000255", "l": "allantoin metabolic process", "d": ["The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0018335", "l": "protein succinylation", "d": ["The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.653457143972261", "identifiers": [{"i": "GO:0009953", "l": "dorsal/ventral pattern formation", "d": ["The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. 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Such vesicles include COPII-coated transport vesicles involved in anterograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:2000051", "l": "negative regulation of non-canonical Wnt signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042501", "l": "serine phosphorylation of STAT protein", "d": ["The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0031154", "l": "culmination involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. 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The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. 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The pathway is found in plants, algae and some protozoa."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.756683046408256", "identifiers": [{"i": "GO:0048562", "l": "embryonic organ morphogenesis", "d": ["Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061056", "l": "sclerotome development", "d": ["The progression of the sclerotome over time, from its initial formation to the mature structure. 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Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. 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At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035139", "l": "pelvic fin morphogenesis", "d": ["The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. 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Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044813", "l": "glycolytic fermentation via PFOR pathway", "d": ["The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. 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The former is a tetramer of the latter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009201", "l": "ribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141063", "l": "epigenetic programming in the central cell", "d": ["The establishment of epigenetic modifications (imprints) in a plant central cell, leading to an asymmetry between the two maternal alleles and the paternal allele, and differential expression of the corresponding alleles in the developing endosperm. This can happen through heterochromatin formation or differential chromatin loop formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140846", "l": "positive regulation of promoter clearance from RNA polymerase II promoter", "d": ["A process that activates or increases the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0045103", "l": "intermediate filament-based process", "d": ["Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046944", "l": "protein carbamoylation", "d": ["The addition of a carbamoyl group to a protein amino acid. 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It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0098775", "l": "curli assembly", "d": ["The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0015847", "l": "putrescine transport", "d": ["The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Microtubules attach to spindle pole bodies at the minus end."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0090605", "l": "submerged biofilm formation", "d": ["A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902258", "l": "positive regulation of apoptotic process involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034441", "l": "plasma lipoprotein particle oxidation", "d": ["The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0003266", "l": "regulation of secondary heart field cardioblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010567", "l": "regulation of ketone catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009202", "l": "deoxyribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:2000816", "l": "negative regulation of mitotic sister chromatid separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045829", "l": "negative regulation of isotype switching", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060497", "l": "mesenchymal-endodermal cell signaling", "d": ["Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072093", "l": "metanephric renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.153640326263854", "identifiers": [{"i": "GO:0061564", "l": "axon development", "d": ["The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001777", "l": "T cell homeostatic proliferation", "d": ["The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900762", "l": "averantin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of averantin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902232", "l": "regulation of positive thymic T cell selection", "d": ["Any process that modulates the frequency, rate or extent of positive thymic T cell selection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044083", "l": "symbiont-mediated perturbation of host Rho signal transduction", "d": ["A process in which a symbiont alters a Rho protein family-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0052164", "l": "symbiont defense to host-produced reactive oxygen species", "d": ["A process in which a symbiont alters or subverts either the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905810", "l": "regulation of excitatory synapse pruning", "d": ["Any process that modulates the frequency, rate or extent of excitatory synapse pruning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003398", "l": "glial cell differentiation involved in amphid sensory organ development", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051973", "l": "positive regulation of telomerase activity", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002477", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.929890650779797", "identifiers": [{"i": "GO:0002822", "l": "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905641", "l": "cellular response to acetaldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0021564", "l": "vagus nerve development", "d": ["The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045645", "l": "positive regulation of eosinophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0022605", "l": "mammalian oogenesis stage", "d": ["A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0039532", "l": "negative regulation of cytoplasmic pattern recognition receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the series of a cytoplasmic pattern recognition receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901442", "l": "regulation of response to furfural", "d": ["Any process that modulates the frequency, rate or extent of response to furfural."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904916", "l": "transmembrane L-lysine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075523", "l": "viral translational frameshifting", "d": ["A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0030177", "l": "positive regulation of Wnt signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006111", "l": "regulation of gluconeogenesis", "d": ["Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019496", "l": "serine-isocitrate lyase pathway", "d": ["A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0021557", "l": "oculomotor nerve development", "d": ["The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075284", "l": "asexual sporulation resulting in formation of a multicellular or syncytial spore", "d": ["The formation of a multicellular or syncytial spore via septations derived from mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:2000278", "l": "regulation of DNA biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of DNA biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904958", "l": "positive regulation of midbrain dopaminergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903688", "l": "positive regulation of border follicle cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of border follicle cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036377", "l": "arbuscular mycorrhizal association", "d": ["A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002630", "l": "positive regulation of proteolysis associated with antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032748", "l": "positive regulation of interleukin-24 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-24 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061288", "l": "mesonephric capsule specification", "d": ["The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0002313", "l": "mature B cell differentiation involved in immune response", "d": ["The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1905314", "l": "semi-lunar valve development", "d": ["The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.626384042261094", "identifiers": [{"i": "GO:0000272", "l": "polysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0032206", "l": "positive regulation of telomere maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0032222", "l": "regulation of synaptic transmission, cholinergic", "d": ["Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003086", "l": "regulation of systemic arterial blood pressure by local renal renin-angiotensin", "d": ["The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035878", "l": "nail development", "d": ["The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016058", "l": "maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling", "d": ["Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036023", "l": "embryonic skeletal limb joint morphogenesis", "d": ["The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.087444505864148", "identifiers": [{"i": "GO:0009611", "l": "response to wounding", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0051899", "l": "membrane depolarization", "d": ["The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046501", "l": "protoporphyrinogen IX metabolic process", "d": ["The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010905", "l": "negative regulation of UDP-glucose catabolic process", "d": ["Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006847", "l": "plasma membrane acetate transport", "d": ["The directed movement of acetate across a plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902385", "l": "glycyrrhetinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905273", "l": "positive regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0009668", "l": "plastid membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032658", "l": "regulation of interleukin-15 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-15 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090252", "l": "epithelium migration involved in imaginal disc-derived wing morphogenesis", "d": ["The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097719", "l": "neural tissue regeneration", "d": ["The regrowth of neural tissue following its loss or destruction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097046", "l": "replication fork progression beyond termination site", "d": ["Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002342", "l": "central B cell deletion", "d": ["The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051016", "l": "barbed-end actin filament capping", "d": ["The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0048370", "l": "lateral mesoderm formation", "d": ["The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0034471", "l": "ncRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of a non-coding RNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071388", "l": "cellular response to cortisone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001986", "l": "negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure", "d": ["Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903393", "l": "positive regulation of adherens junction organization", "d": ["Any process that activates or increases the frequency, rate or extent of adherens junction organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0170033", "l": "L-amino acid metabolic process", "d": ["The chemical reactions and pathways involving an L-amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072336", "l": "negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. 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Ribosomal RNAs (rRNA) genes are transcribed by RNA polymerase I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0006067", "l": "ethanol metabolic process", "d": ["The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060450", "l": "positive regulation of hindgut contraction", "d": ["Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031041", "l": "O-glycan processing, core 5", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060735", "l": "regulation of eIF2 alpha phosphorylation by dsRNA", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901074", "l": "regulation of engulfment of apoptotic cell", "d": ["Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0008355", "l": "olfactory learning", "d": ["Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900712", "l": "positive regulation of tensidol B biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007463", "l": "R2/R5 cell fate commitment", "d": ["The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901131", "l": "kanamycin metabolic process", "d": ["The chemical reactions and pathways involving kanamycin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.915726484813547", "identifiers": [{"i": "GO:0046148", "l": "pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1903795", "l": "regulation of inorganic anion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0009561", "l": "megagametogenesis", "d": ["The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. 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A binucleate endosperm mother cell is formed at the center."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032746", "l": "positive regulation of interleukin-22 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-22 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001188", "l": "regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006201", "l": "GMP catabolic process to IMP", "d": ["The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048078", "l": "positive regulation of compound eye pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902071", "l": "regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900343", "l": "negative regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0015827", "l": "tryptophan transport", "d": ["The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.054967706738452", "identifiers": [{"i": "GO:0002712", "l": "regulation of B cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of B cell mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045324", "l": "late endosome to vacuole transport", "d": ["The directed movement of substances from late endosomes to the vacuole. 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"identifiers": [{"i": "GO:0090182", "l": "regulation of secretion of lysosomal enzymes", "d": ["Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000760", "l": "adaptation to pheromone regulating conjugation with mutual genetic exchange", "d": ["In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903111", "l": "negative regulation of single-strand break repair via homologous recombination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002747", "l": "antigen processing and presentation following phagocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0050688", "l": "regulation of defense response to virus", "d": ["Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035513", "l": "oxidative RNA demethylation", "d": ["The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": 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"identifiers": [{"i": "GO:0035134", "l": "post-embryonic dorsal fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010896", "l": "regulation of triglyceride catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0000422", "l": "autophagy of mitochondrion", "d": ["The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902940", "l": "positive regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990767", "l": "prostaglandin receptor internalization", "d": ["The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.472392306593008", "identifiers": [{"i": "GO:0002682", "l": "regulation of immune system process", "d": ["Any process that modulates the frequency, rate, or extent of an immune system process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060650", "l": "epithelial cell proliferation involved in mammary gland bud elongation", "d": ["The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.551667831314546", "identifiers": [{"i": "GO:0035738", "l": "envenomation resulting in modulation of process in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140204", "l": "pyridoxal import across plasma membrane", "d": ["The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904592", "l": "positive regulation of protein refolding", "d": ["Any process that activates or increases the frequency, rate or extent of protein refolding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0061114", "l": "branching involved in pancreas morphogenesis", "d": ["The process in which the branches of the pancreas are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903705", "l": "positive regulation of siRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of siRNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007385", "l": "specification of segmental identity, abdomen", "d": ["The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. 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transcription", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048138", "l": "germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097066", "l": "response to thyroid hormone", "d": ["A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000120", "l": "positive regulation of sodium-dependent phosphate transport", "d": ["Any process that activates or increases the frequency, rate or extent of 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frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901109", "l": "granaticin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of granaticin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0010416", "l": "arabinoxylan-containing compound metabolic process", "d": ["The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009455", "l": "redox taxis", "d": ["The directed movement of a motile cell or organism in response to redox potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071672", "l": "negative regulation of smooth muscle cell chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903412", "l": "response to bile acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0072666", "l": "establishment of protein localization to vacuole", "d": ["The directed movement of a protein to a specific location in a vacuole."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000236", "l": "mitotic prometaphase", "d": ["The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0016100", "l": "monoterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140917", "l": "zinc ion import into mitochondrion", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061010", "l": "gallbladder development", "d": ["The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901850", "l": "7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process", "d": ["The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015782", "l": "CMP-N-acetylneuraminate transmembrane transport", "d": ["The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0000955", "l": "amino acid catabolic process via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. 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Signaling never reaches a level of consciousness."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0048525", "l": "negative regulation of viral process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009215", "l": "purine deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140516", "l": "mitotic nuclear pore complex disassembly", "d": ["The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019475", "l": "L-lysine catabolic process to acetate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.672771840408203", "identifiers": [{"i": "GO:0043447", "l": "alkane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021552", "l": "midbrain-hindbrain boundary structural organization", "d": ["The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0006266", "l": "DNA ligation", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000352", "l": "negative regulation of endothelial cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0061643", "l": "chemorepulsion of axon", "d": ["The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032249", "l": "regulation of adenosine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0032618", "l": "interleukin-15 production", "d": ["The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0045066", "l": "regulatory T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. 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This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007291", "l": "sperm individualization", "d": ["The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010405", "l": "arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1905161", "l": "protein localization to phagocytic vesicle", "d": ["A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140717", "l": "entry into host through the stromata", "d": ["Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031538", "l": "negative regulation of anthocyanin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051757", "l": "meiotic sister chromatid separation", "d": ["The process in which sister chromatids are physically detached from each other during meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060197", "l": "cloacal septation", "d": ["The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0150070", "l": "regulation of arginase activity", "d": ["Any process that modulates the frequency, rate or extent of arginase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075194", "l": "positive regulation of haustorium mother cell formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072315", "l": "metanephric glomerular epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0046685", "l": "response to arsenic-containing substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0045455", "l": "ecdysteroid metabolic process", "d": ["The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002297", "l": "T-helper 2 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120076", "l": "negative regulation of endocardial cushion cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0008089", "l": "anterograde axonal transport", "d": ["The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.31275651554779", "identifiers": [{"i": "GO:1902105", "l": "regulation of leukocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of leukocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046061", "l": "dATP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.683527111924249", "identifiers": [{"i": "GO:0071674", "l": "mononuclear cell migration", "d": ["The movement of a mononuclear cell within or between different tissues and organs of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110160", "l": "negative regulation of mitotic spindle formation (spindle phase one)", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035045", "l": "sperm plasma membrane disassembly", "d": ["The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0099601", "l": "regulation of neurotransmitter receptor activity", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.024411547311772", "identifiers": [{"i": "GO:0021575", "l": "hindbrain morphogenesis", "d": ["The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070682", "l": "proteasome regulatory particle assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003114", "l": "positive regulation of heart rate by circulating norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001044", "l": "regulation of integrin-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015823", "l": "phenylalanine transport", "d": ["The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900979", "l": "positive regulation of tatiopterin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0002572", "l": "pro-T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070384", "l": "Harderian gland development", "d": ["The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902976", "l": "premeiotic DNA replication preinitiation complex assembly", "d": ["Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070096", "l": "mitochondrial outer membrane translocase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.655379925225219", "identifiers": [{"i": "GO:0001709", "l": "cell fate determination", "d": ["The cellular developmental process involved in cell fate commitment that occurs after cell fate specification, in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904896", "l": "ESCRT complex disassembly", "d": ["The disaggregation of an ESCRT complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0052128", "l": "positive energy taxis", "d": ["The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903324", "l": "negative regulation of snoRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0051153", "l": "regulation of striated muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of striated muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009244", "l": "lipopolysaccharide core region biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032379", "l": "positive regulation of intracellular lipid transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003061", "l": "positive regulation of the force of heart contraction by norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046689", "l": "response to mercury ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000685", "l": "positive regulation of cellular response to X-ray", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to X-ray."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990155", "l": "Dsc E3 ubiquitin ligase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0090169", "l": "regulation of spindle assembly", "d": ["Any process that modulates the rate, frequency or extent of spindle assembly. 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The sperm aster ensures the appropriate positioning of the male and female pronuclei."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021703", "l": "locus ceruleus development", "d": ["The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. 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Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046248", "l": "alpha-pinene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0050942", "l": "positive regulation of pigment cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pigment cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904917", "l": "L-arginine transmembrane transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000442", "l": "positive regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003356", "l": "regulation of cilium beat frequency", "d": ["Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902530", "l": "positive regulation of protein linear polyubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904319", "l": "negative regulation of smooth muscle contraction involved in micturition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021502", "l": "neural fold elevation formation", "d": ["The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0098957", "l": "anterograde axonal transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900038", "l": "negative regulation of cellular response to hypoxia", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021633", "l": "optic nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061017", "l": "hepatoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. 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The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901944", "l": "miltiradiene metabolic process", "d": ["The chemical reactions and pathways involving miltiradiene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000123", "l": "positive regulation of stomatal complex development", "d": ["Any process that activates or increases the frequency, rate or extent of stomatal complex development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0072087", "l": "renal vesicle development", "d": ["The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. 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Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000018", "l": "regulation of male gonad development", "d": ["Any process that modulates the frequency, rate or extent of male gonad development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.335082997926719", "identifiers": [{"i": "GO:0022613", "l": "ribonucleoprotein complex biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. 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Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903243", "l": "negative regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002471", "l": "monocyte antigen processing and presentation", "d": ["The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902722", "l": "positive regulation of prolactin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of prolactin secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070782", "l": "phosphatidylserine exposure on apoptotic cell surface", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090644", "l": "age-related resistance", "d": ["An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0019319", "l": "hexose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905872", "l": "negative regulation of protein localization to cell leading edge", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010306", "l": "rhamnogalacturonan II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042489", "l": "negative regulation of odontogenesis of dentin-containing tooth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051865", "l": "protein autoubiquitination", "d": ["The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. 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Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. 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Derived from vegetable sources."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001731", "l": "formation of translation preinitiation complex", "d": ["The joining of the small ribosomal subunit, ternary complex, and mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1900913", "l": "positive regulation of olefin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904563", "l": "phosphatidylinositol 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902529", "l": "negative regulation of protein linear polyubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901823", "l": "delta-carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of delta-carotene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:1902107", "l": "positive regulation of leukocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032347", "l": "regulation of aldosterone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051296", "l": "establishment of meiotic spindle orientation", "d": ["Any process that set the alignment of meiotic spindle relative to other cellular structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0050762", "l": "depsipeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009722", "l": "detection of cytokinin stimulus", "d": ["The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034148", "l": "negative regulation of toll-like receptor 5 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033396", "l": "beta-alanine biosynthetic process via 3-ureidopropionate", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904471", "l": "negative regulation of endothelin production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003083", "l": "negative regulation of renal output by angiotensin", "d": ["The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099630", "l": "postsynaptic neurotransmitter receptor cycle", "d": ["The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. 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Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072121", "l": "head kidney maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006285", "l": "base-excision repair, AP site formation", "d": ["The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900030", "l": "regulation of pectin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pectin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061344", "l": "regulation of cell adhesion involved in heart morphogenesis", "d": ["Any process that modulates the extent of cell adhesion contributing to the shaping of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0031111", "l": "negative regulation of microtubule polymerization or depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006614", "l": "SRP-dependent cotranslational protein targeting to membrane", "d": ["The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.624069114104344", "identifiers": [{"i": "GO:0046700", "l": "heterocycle catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036285", "l": "SAGA complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051395", "l": "negative regulation of nerve growth factor receptor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.601382156057369", "identifiers": [{"i": "GO:0002286", "l": "T cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990839", "l": "response to endothelin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. 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Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033197", "l": "response to vitamin E", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060162", "l": "negative regulation of phospholipase C-activating dopamine receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0016126", "l": "sterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.660071514290692", "identifiers": [{"i": "GO:0012501", "l": "programmed cell death", "d": ["A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). 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Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0008595", "l": "anterior/posterior axis specification, embryo", "d": ["The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0072235", "l": "metanephric distal tubule development", "d": ["The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. 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The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048533", "l": "sporocyte differentiation", "d": ["The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010400", "l": "rhamnogalacturonan I side chain metabolic process", "d": ["The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903255", "l": "hercynylselenocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hercynylselenocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010106", "l": "cellular response to iron ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron 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{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120176", "l": "positive regulation of torso signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the torso signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061325", "l": "cell proliferation involved in outflow tract morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071338", "l": "positive regulation of hair follicle cell proliferation", "d": ["Any process that activates or increases the rate or extent of hair follicle cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905487", "l": "negative regulation of anterior/posterior axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0072008", "l": "glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006176", "l": "dATP biosynthetic process from ADP", "d": ["The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036471", "l": "cellular response to glyoxal", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0006213", "l": "pyrimidine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1902669", "l": "positive regulation of axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of axon guidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903174", "l": "fatty alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fatty alcohol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008364", "l": "pupal chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based pupal cuticle. 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In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. 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The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045653", "l": "negative regulation of megakaryocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905375", "l": "cellular response to homocysteine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0140975", "l": "disruption of cellular anatomical structure in another organism", "d": ["The disruption of a cellular component of another organism, leading to damage or temporary subversion of that structure. 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A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1902101", "l": "positive regulation of metaphase/anaphase transition of cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0030253", "l": "protein secretion by the type I secretion system", "d": ["The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021629", "l": "olfactory nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. 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The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003345", "l": "proepicardium cell migration involved in pericardium morphogenesis", "d": ["The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000491", "l": "positive regulation of hepatic stellate cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048302", "l": "regulation of isotype switching to IgG isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003315", "l": "heart rudiment formation", "d": ["The developmental process pertaining to the initial formation of the heart rudiment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901524", "l": "regulation of mitophagy", "d": ["Any process that modulates the frequency, rate or extent of macromitophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051091", "l": "positive regulation of DNA-binding transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0060026", "l": "convergent extension", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061016", "l": "snRNA localization to Cajal body", "d": ["The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090135", "l": "actin filament branching", "d": ["The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048462", "l": "carpel formation", "d": ["The process that gives rise to the carpel. 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The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010791", "l": "DNA double-strand break processing involved in repair via synthesis-dependent strand annealing", "d": ["The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0048442", "l": "sepal development", "d": ["The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035742", "l": "activated CD8-positive, alpha-beta T cell proliferation", "d": ["The expansion of an activated CD8-positive, alpha-beta T cell population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007260", "l": "tyrosine phosphorylation of STAT protein", "d": ["The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032237", "l": "activation of store-operated calcium channel activity", "d": ["A process that initiates the activity of an inactive store-operated calcium channel."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902424", "l": "negative regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903488", "l": "negative regulation of lactation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lactation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019858", "l": "cytosine metabolic process", "d": ["The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021737", "l": "emboliform nucleus development", "d": ["The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0051781", "l": "positive regulation of cell division", "d": ["Any process that activates or increases the frequency, rate or extent of cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097366", "l": "response to bronchodilator", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0120263", "l": "positive regulation of heterochromatin organization", "d": ["Any process that activates or increases the frequency, rate or extent of heterochromatin organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035654", "l": "clathrin-coated vesicle cargo loading, AP-3-mediated", "d": ["Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1901402", "l": "negative regulation of tetrapyrrole metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034096", "l": "positive regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.800431741157325", "identifiers": [{"i": "GO:0031399", "l": "regulation of protein modification process", "d": ["Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071410", "l": "cellular response to cyclopentenone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.402634366777022", "identifiers": [{"i": "GO:0006195", "l": "purine nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904538", "l": "regulation of glycolytic process through fructose-6-phosphate", "d": ["Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0031033", "l": "myosin filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:1904888", "l": "cranial skeletal system development", "d": ["The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. 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This process pertains to the initial formation of the structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106081", "l": "maltose import across plasma membrane", "d": ["The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036101", "l": "leukotriene B4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071784", "l": "endoplasmic reticulum cisternal network assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. 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Unlike conventional antigens, which activate T cells by interacting with specific receptors on the surface of these cells, superantigens can stimulate T cells by binding to regions outside the antigen-binding site. Superantigens can activate a large proportion of T cells, leading to an exaggerated immune response. This excessive activation can result in the release of a large amount of cytokines such as tumor necrosis factor and interleukin-2. The massive cytokine release can lead to an acute toxic shock, causing symptoms such as fever and organ damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904514", "l": "positive regulation of initiation of premeiotic DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0003413", "l": "chondrocyte differentiation involved in endochondral bone morphogenesis", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. 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An example of this process is found in Mus musculus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000131", "l": "regulation of tyramine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of tyramine signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044529", "l": "regulation of mitochondrial rRNA stability", "d": ["Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. 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The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.151319539368089", "identifiers": [{"i": "GO:0002687", "l": "positive regulation of leukocyte migration", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900520", "l": "positive regulation of response to pullulan", "d": ["Any process that activates or increases the frequency, rate or extent of response to pullulan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033340", "l": "pelvic fin development", "d": ["The process whose 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042543", "l": "protein N-linked glycosylation via arginine", "d": ["The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080192", "l": "primary thickening", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903077", "l": "negative regulation of protein localization to plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0072663", "l": "establishment of protein 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The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097095", "l": "frontonasal suture morphogenesis", "d": ["The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002411", "l": "T cell tolerance induction to tumor cell", "d": ["A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052034", "l": "effector-mediated suppression of host pattern-triggered immunity", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050948", "l": "positive regulation of early stripe melanocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098909", "l": "regulation of cardiac muscle cell action potential involved in regulation of contraction", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904583", "l": "response to polyamine macromolecule", "d": ["Any process that 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The skin is the external membranous integument of an animal. 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The atrial septum separates the upper chambers (the atria) of the heart from one another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000959", "l": "positive regulation of cyclodextrin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0000378", "l": "RNA exon ligation", "d": ["The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000476", "l": "maturation of 4.5S rRNA", "d": ["Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001238", "l": "positive regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901256", "l": "regulation of macrophage colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000383", "l": "regulation of ectoderm development", "d": ["Any process that modulates the frequency, rate or extent of ectoderm development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014050", "l": "negative regulation of glutamate secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0043704", "l": "photoreceptor cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. 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When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090237", "l": "regulation of arachidonic acid secretion", "d": ["Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061680", "l": "Entner-Doudoroff pathway through gluconate to D-glyceraldehyde", "d": ["The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034631", "l": "microtubule anchoring at spindle pole body", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. 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A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0002863", "l": "positive regulation of inflammatory response to antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099179", "l": "regulation of synaptic membrane adhesion", "d": ["Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0098704", "l": "carbohydrate import across plasma membrane", "d": ["The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0090306", "l": "meiotic spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0070302", "l": "regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033572", "l": "transferrin transport", "d": ["The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007540", "l": "sex determination, establishment of X:A ratio", "d": ["The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030846", "l": "termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["An RNA polymerase II transcription termination process in which cleavage and polyadenylylation of the mRNA 3' end are coupled to transcription termination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1902108", "l": "regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any regulation of mitochondrial membrane permeability that is involved in apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033512", "l": "L-lysine catabolic process to acetyl-CoA via saccharopine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070713", "l": "RNA guanosine-cytidine insertion", "d": ["The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0106135", "l": "negative regulation of cardiac muscle cell contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1902291", "l": "cell cycle DNA replication DNA ligation", "d": ["Any DNA ligation that is involved in cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032435", "l": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070580", "l": "base J metabolic process", "d": ["The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. 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Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019386", "l": "methanogenesis, from carbon dioxide", "d": ["The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901341", "l": "positive regulation of store-operated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0099548", "l": "trans-synaptic signaling by nitric oxide", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000965", "l": "positive regulation of cellooligosaccharide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090496", "l": "mesenchyme migration involved in limb bud formation", "d": ["The migration of mesenchymal tissue that contributes to the formation of a limb bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900595", "l": "(+)-kotanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-kotanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010710", "l": "regulation of collagen catabolic process", "d": ["Any process that modulates the rate, frequency or extent of collagen catabolism. 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Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900036", "l": "positive regulation of cellular response to heat", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to heat."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048322", "l": "axial mesodermal cell fate commitment", "d": ["The process in which a cell becomes committed to become an axial mesoderm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021844", "l": "interneuron sorting involved in substrate-independent cerebral cortex tangential migration", "d": ["The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.584647820776595", "identifiers": [{"i": "GO:0104004", "l": "cellular response to environmental stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901117", "l": "cephamycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cephamycin C."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0062044", "l": "negative regulation of cardiac epithelial to mesenchymal transition", "d": ["Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036109", "l": "alpha-linolenic acid metabolic process", "d": ["The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060319", "l": "primitive erythrocyte differentiation", "d": ["Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060310", "l": "regulation of elastin catabolic process", "d": ["Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035937", "l": "estrogen secretion", "d": ["The regulated release of estrogen into the circulatory system. 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Identity is considered to be the aggregate of characteristics by which a structure is recognized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0046460", "l": "neutral lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070157", "l": "mitochondrial prolyl-tRNA aminoacylation", "d": ["The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0021879", "l": "forebrain neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070149", "l": "mitochondrial glutamyl-tRNA aminoacylation", "d": ["The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0090697", "l": "post-embryonic plant organ morphogenesis", "d": ["Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.996708891219072", "identifiers": [{"i": "GO:0061333", "l": "renal tubule morphogenesis", "d": ["The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060452", "l": "positive regulation of cardiac muscle contraction", "d": ["Any process that increases the frequency, rate or extent of cardiac muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036390", "l": "pre-replicative complex assembly involved in bacterial-type DNA replication", "d": ["The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0140747", "l": "regulation of ncRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of transcription of a non-protein coding gene from a DNA-template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051455", "l": "spindle attachment to meiosis I kinetochore", "d": ["The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0035315", "l": "hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hair cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035799", "l": "ureter maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903669", "l": "positive regulation of chemorepellent activity", "d": ["Any process that activates or increases the frequency, rate or extent of chemorepellent activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051092", "l": "positive regulation of NF-kappaB transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900716", "l": "regulation of violaceol II biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000425", "l": "regulation of apoptotic cell clearance", "d": ["Any process that modulates the frequency, rate or extent of apoptotic cell clearance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.756683046408256", "identifiers": [{"i": "GO:0006403", "l": "RNA localization", "d": ["A process in which RNA is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905285", "l": "fibrous ring of heart morphogenesis", "d": ["The developmental process by which a fibrous ring of heart is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001177", "l": "regulation of transcription open complex formation at RNA polymerase II promoter", "d": ["Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035911", "l": "descending aorta morphogenesis", "d": ["The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006797", "l": "polyphosphate metabolic process", "d": ["The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045837", "l": "negative regulation of membrane potential", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010609", "l": "mRNA localization resulting in post-transcriptional regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140380", "l": "psilocybin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0140250", "l": "regulation protein catabolic process at synapse", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072107", "l": "positive regulation of ureteric bud formation", "d": ["Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0086051", "l": "membrane repolarization during Purkinje myocyte action potential", "d": ["The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0045764", "l": "positive regulation of amino acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0015714", "l": "phosphoenolpyruvate transport", "d": ["The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031887", "l": "lipid droplet transport along microtubule", "d": ["The directed movement of a lipid droplet along a microtubule, mediated by motor proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048142", "l": "germarium-derived cystoblast division", "d": ["The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. 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Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045065", "l": "cytotoxic T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090455", "l": "ornithine transmembrane import into vacuole", "d": ["The directed movement of ornithine into the vacuole across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1901913", "l": "regulation of capsule organization", "d": ["Any process that modulates the frequency, rate or extent of capsule organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0035601", "l": "protein deacylation", "d": ["The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098931", "l": "virion attachment to host cell flagellum", "d": ["The process by which a virion attaches to a the host cell flagellum. 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[{"i": "GO:0090551", "l": "response to manganese starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033471", "l": "GDP-L-galactose metabolic process", "d": ["The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019510", "l": "S-adenosylhomocysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075269", "l": "positive regulation of aecium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046362", "l": "ribitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036519", "l": "chemorepulsion of serotonergic neuron axon", "d": ["The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "40.254316406276949", "identifiers": [{"i": "GO:0098916", "l": "anterograde trans-synaptic signaling", "d": ["Cell-cell signaling from pre to post-synapse, across the synaptic cleft."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080113", "l": "regulation of seed growth", "d": ["Any process that modulates the frequency, rate or extent of growth of the seed of an plant."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021615", "l": "glossopharyngeal nerve morphogenesis", "d": ["The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. 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The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902841", "l": "regulation of netrin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019745", "l": "pentacyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001298", "l": "N(omega),N(omega)-dimethyl-L-arginine metabolic process", "d": ["The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904323", "l": "regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0070649", "l": "formin-nucleated actin cable assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. 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Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900315", "l": "regulation of maltopentaose transport", "d": ["Any process that modulates the frequency, rate or extent of maltopentaose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070994", "l": "detection of oxidative stress", "d": ["The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051888", "l": "positive regulation of timing of exogen", "d": ["Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060709", "l": "glycogen cell differentiation involved in embryonic placenta development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. 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A radial glial cell is a precursor cell that gives rise to neurons and astrocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045004", "l": "DNA replication proofreading", "d": ["Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1903184", "l": "L-dopa metabolic process", "d": ["The chemical reactions and pathways involving L-dopa."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001241", "l": "positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903895", "l": "negative regulation of IRE1-mediated unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015877", "l": "biopterin transport", "d": ["The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018903", "l": "1,3-dichloropropene metabolic process", "d": ["The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904210", "l": "VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0042483", "l": "negative regulation of odontogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014844", "l": "myoblast proliferation involved in skeletal muscle regeneration", "d": ["The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003330", "l": "regulation of extracellular matrix constituent secretion", "d": ["Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0098610", "l": "adhesion between unicellular organisms", "d": ["The attachment of two unicellular organisms to each other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090261", "l": "positive regulation of inclusion body assembly", "d": ["Any process that increases the rate, frequency, or extent of inclusion body assembly. 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It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060744", "l": "mammary gland branching involved in thelarche", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098002", "l": "receptor-mediated bacteriophage irreversible attachment to host cell", "d": ["The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1900247", "l": "regulation of cytoplasmic translational elongation", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061029", "l": "eyelid development in camera-type eye", "d": ["The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034345", "l": "negative regulation of type III interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030495", "l": "bacteriochlorophyll catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035358", "l": "regulation of peroxisome proliferator activated receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0140280", "l": "negative regulation of mitotic division septum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. 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This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901387", "l": "positive regulation of voltage-gated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032605", "l": "hepatocyte growth factor production", "d": ["The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032914", "l": "positive regulation of transforming growth factor beta1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000585", "l": "positive regulation of platelet-derived growth factor receptor-alpha signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905847", "l": "negative regulation of cellular response to oxidopamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061880", "l": "regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0090184", "l": "positive regulation of kidney development", "d": ["Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090505", "l": "epiboly involved in wound healing", "d": ["The expansion of one cell sheet over other cells involved in wound healing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901429", "l": "negative regulation of syringal lignin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039557", "l": "symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071984", "l": "maintenance of reproductive diapause", "d": ["The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900373", "l": "positive regulation of purine nucleotide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0032076", "l": "negative regulation of deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0015798", "l": "myo-inositol transport", "d": ["The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002586", "l": "regulation of antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000173", "l": "negative regulation of branching morphogenesis of a nerve", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061934", "l": "regulation of adenine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of an adenine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.625268296404869", "identifiers": [{"i": "GO:0031344", "l": "regulation of cell projection organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0090594", "l": "inflammatory response to wounding", "d": ["The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.314050959231352", "identifiers": [{"i": "GO:0051147", "l": "regulation of muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0021825", "l": "substrate-dependent cerebral cortex tangential migration", "d": ["The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071646", "l": "regulation of macrophage inflammatory protein-1 gamma production", "d": ["Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106164", "l": "positive regulation of exonucleolytic catabolism of deadenylated mRNA", "d": ["Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060694", "l": "regulation of cholesterol transporter activity", "d": ["Any process that modulates the rate, frequency, or extent of cholesterol transporter activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071464", "l": "cellular response to hydrostatic pressure", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000819", "l": "regulation of nucleotide-excision repair", "d": ["Any process that modulates the frequency, rate or extent of nucleotide-excision repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097116", "l": "gephyrin clustering involved in postsynaptic density assembly", "d": ["The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.472954561636897", "identifiers": [{"i": "GO:0031347", "l": "regulation of defense response", "d": ["Any process that modulates the frequency, rate or extent of a defense response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034140", "l": "negative regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021937", "l": "cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation", "d": ["The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010600", "l": "regulation of auxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006904", "l": "vesicle docking involved in exocytosis", "d": ["The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006154", "l": "adenosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071580", "l": "regulation of zinc ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0050709", "l": "negative regulation of protein secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0071266", "l": "'de novo' L-methionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048652", "l": "polyphenic determination, influence by genetic factors", "d": ["The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044510", "l": "envenomation resulting in positive regulation of signal transduction in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052103", "l": "induction of host induced systemic resistance", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0031468", "l": "nuclear membrane reassembly", "d": ["The reformation of the nuclear membranes following their breakdown in the context of a normal process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0042360", "l": "vitamin E metabolic process", "d": ["The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.528812303068719", "identifiers": [{"i": "GO:0019438", "l": "aromatic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098709", "l": "glutathione import across plasma membrane", "d": ["The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000444", "l": "negative regulation of toll-like receptor 21 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900189", "l": "positive regulation of cell adhesion involved in single-species biofilm formation", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001110", "l": "RNA polymerase III promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901740", "l": "negative regulation of myoblast fusion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.796139606449842", "identifiers": [{"i": "GO:0055092", "l": "sterol homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of sterol within an organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071891", "l": "N-terminal peptidyl-proline dimethylation involved in translation", "d": ["An N-terminal peptidyl-proline dimethylation process that contributes to translation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097754", "l": "clathrin-mediated membrane bending", "d": ["A membrane bending process mediated by clathrin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902755", "l": "sulfurated eukaryotic molybdenum cofactor(2-) metabolic process", "d": ["The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0031650", "l": "regulation of heat generation", "d": ["Any process that modulates the rate or extent of heat generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099586", "l": "release of sequestered calcium ion into postsynaptic cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001101", "l": "maltopentaose transport", "d": ["The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002725", "l": "negative regulation of T cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905380", "l": "regulation of snRNA transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0052863", "l": "1-deoxy-D-xylulose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905610", "l": "regulation of mRNA cap binding", "d": ["Any process that modulates the frequency, rate or extent of mRNA cap binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021684", "l": "cerebellar granular layer formation", "d": ["The process that gives rise to the cerebellar granule layer. 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Types of silicate include unisilicates, metasilicates and hydrous silicates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.356622992911923", "identifiers": [{"i": "GO:1903530", "l": "regulation of secretion by cell", "d": ["Any process that modulates the frequency, rate or extent of secretion by cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090073", "l": "positive regulation of protein homodimerization activity", "d": ["Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032471", "l": "negative regulation of endoplasmic reticulum calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150013", "l": "negative regulation of neuron projection arborization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0008343", "l": "adult feeding behavior", "d": ["Feeding behavior in a fully developed and mature organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0001583", "l": "detection of chemical stimulus involved in sensory perception of salty taste", "d": ["The series of events required for a salty taste stimulus to be received and converted to a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0002118", "l": "aggressive behavior", "d": ["A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0015879", "l": "carnitine transport", "d": ["The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060267", "l": "positive regulation of respiratory burst", "d": ["Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902012", "l": "poly(ribitol phosphate) teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0034776", "l": "response to histamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900886", "l": "positive regulation of tridecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0098543", "l": "detection of other organism", "d": ["The series of events in which a stimulus from another organism is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015885", "l": "5-formyltetrahydrofolate transport", "d": ["The directed movement of 5-formyltetrahydrofolate, the 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990481", "l": "mRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an mRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045429", "l": "positive regulation of nitric oxide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009758", "l": "carbohydrate utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018102", "l": "peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine", "d": ["The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903186", "l": "regulation of vitellogenesis", "d": ["Any process that modulates the frequency, rate or extent of vitellogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001110", "l": "negative regulation of lens epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018029", "l": "peptidyl-lysine palmitoylation", "d": ["The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010218", "l": "response to far red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0009950", "l": "dorsal/ventral axis specification", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098582", "l": "innate vocalization behavior", "d": ["A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0021756", "l": "striatum development", "d": ["The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0150136", "l": "regulation of interleukin-37 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-37 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072151", "l": "mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070317", "l": "negative regulation of G0 to G1 transition", "d": ["A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035945", "l": "mitochondrial ncRNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061589", "l": "calcium activated phosphatidylserine scrambling", "d": ["The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905001", "l": "negative regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.558450055965587", "identifiers": [{"i": "GO:0002456", "l": "T cell mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043376", "l": "regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010387", "l": "COP9 signalosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000944", "l": "positive regulation of amylopectin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010346", "l": "shoot axis formation", "d": ["The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.900010570698157", "identifiers": [{"i": "GO:0010648", "l": "negative regulation of cell communication", "d": ["Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070575", "l": "peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation", "d": ["The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097393", "l": "telomeric repeat-containing RNA transcription", "d": ["The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000312", "l": "regulation of kainate selective glutamate receptor activity", "d": ["Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007280", "l": "pole cell migration", "d": ["The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990067", "l": "intrachromosomal DNA recombination", "d": ["The process of DNA recombination occurring within a single chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0032075", "l": "positive regulation of nuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140374", "l": "antiviral innate immune response", "d": ["A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006249", "l": "dCMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.760981911179996", "identifiers": [{"i": "GO:0061531", "l": "primary amine secretion", "d": ["The regulated release of a primary amine by a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0006825", "l": "copper ion transport", "d": ["The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003392", "l": "cell adhesion involved in retrograde extension", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072438", "l": "response to DNA replication checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1900912", "l": "negative regulation of olefin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071267", "l": "L-methionine salvage", "d": ["Any process that generates L-methionine from derivatives of it, without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000636", "l": "positive regulation of primary miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of primary microRNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046127", "l": "pyrimidine deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:2000573", "l": "positive regulation of DNA biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070474", "l": "positive regulation of uterine smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of uterine smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0017038", "l": "protein import", "d": ["The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902425", "l": "positive regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015836", "l": "lipid-linked peptidoglycan transport", "d": ["The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0002862", "l": "negative regulation of inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048158", "l": "oogonium stage", "d": ["The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044835", "l": "hydrogen generation via nitrogenase", "d": ["The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043561", "l": "regulation of translational initiation in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051755", "l": "meiotic sister chromatid arm separation", "d": ["The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0007020", "l": "microtubule nucleation", "d": ["The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0046037", "l": "GMP metabolic process", "d": ["The chemical reactions and pathways involving GMP, guanosine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901065", "l": "syringal lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of syringal lignin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0006868", "l": "glutamine transport", "d": ["The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030240", "l": "skeletal muscle thin filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0051275", "l": "beta-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-glucans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003347", "l": "epicardial cell to mesenchymal cell transition", "d": ["A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035365", "l": "regulation of thymine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018909", "l": "dodecyl sulfate metabolic process", "d": ["The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019467", "l": "ornithine catabolic process, by decarboxylation", "d": ["The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0001951", "l": "intestinal D-glucose absorption", "d": ["Uptake of D-glucose into the blood by absorption from the small intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0019321", "l": "pentose metabolic process", "d": ["The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902070", "l": "positive regulation of sphingolipid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of sphingolipid signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034254", "l": "regulation of urea catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0006567", "l": "threonine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070730", "l": "cAMP transport", "d": ["The directed movement of cyclic AMP (cAMP), into, out of or within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034630", "l": "RITS complex localization", "d": ["Any process in which a RITS complex is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900138", "l": "negative regulation of phospholipase A2 activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061478", "l": "response to platelet aggregation inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044758", "l": "modulation by symbiont of host synaptic transmission", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0021785", "l": "branchiomotor neuron axon guidance", "d": ["The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0006390", "l": "mitochondrial transcription", "d": ["The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900171", "l": "positive regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.375074843138819", "identifiers": [{"i": "GO:0043066", "l": "negative regulation of apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050887", "l": "determination of sensory modality", "d": ["The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0150022", "l": "apical dendrite development", "d": ["The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000790", "l": "regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018533", "l": "peptidyl-cysteine acetylation", "d": ["The acetylation of peptidyl-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.593242189043409", "identifiers": [{"i": "GO:0032200", "l": "telomere organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0090293", "l": "nitrogen catabolite regulation of transcription", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007383", "l": "specification of segmental identity, antennal segment", "d": ["The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0038083", "l": "peptidyl-tyrosine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.151319539368089", "identifiers": [{"i": "GO:0009267", "l": "cellular response to starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0170044", "l": "non-proteinogenic amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0099553", "l": "trans-synaptic signaling by endocannabinoid, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0075025", "l": "initiation of appressorium formation", "d": ["The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060777", "l": "compound leaf morphogenesis", "d": ["The leaf morphogenesis process that results in the shaping of a compound leaf. 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This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.083257375933542", "identifiers": [{"i": "GO:0003012", "l": "muscle system process", "d": ["A organ system process carried out at the level of a muscle. 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This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031651", "l": "negative regulation of heat generation", "d": ["Any process that stops, prevents, or reduces the rate or extent of heat generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901801", "l": "1,5-anhydro-D-fructose metabolic process", "d": ["The chemical reactions and pathways involving 1,5-anhydro-D-fructose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032973", "l": "amino acid export across plasma membrane", "d": ["The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.074998230512762", "identifiers": [{"i": "GO:0120252", "l": "hydrocarbon metabolic process", "d": ["The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010716", "l": "negative regulation of extracellular matrix disassembly", "d": ["Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. 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The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046064", "l": "dCMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903760", "l": "regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002537", "l": "nitric oxide production involved in inflammatory response", "d": ["The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904136", "l": "regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010144", "l": "pyridoxal phosphate biosynthetic process from pyridoxamine", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1900864", "l": "mitochondrial RNA modification", "d": ["Any RNA modification that takes place in mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901501", "l": "response to xylene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061446", "l": "endocardial cushion cell fate determination", "d": ["The process involved in endocardial cushion cell fate commitment. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007157", "l": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "d": ["The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902367", "l": "negative regulation of Notch signaling pathway involved in somitogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0015770", "l": "sucrose transport", "d": ["The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. 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DIF-2 is a chlorinated alkylphenone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046010", "l": "positive regulation of circadian sleep/wake cycle, non-REM sleep", "d": ["Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018866", "l": "adamantanone metabolic process", "d": ["The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002669", "l": "positive regulation of T cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell anergy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0019585", "l": "glucuronate metabolic process", "d": ["The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:2000155", "l": "positive regulation of cilium-dependent cell motility", "d": ["Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0003260", "l": "cardioblast migration", "d": ["The orderly movement of a cardiac progenitor cell to form the heart field. 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Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019648", "l": "formaldehyde assimilation via xylulose monophosphate cycle", "d": ["The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. 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RNA polymerase III has an intrinsic ability to terminate transcription upon incorporation of at least 4 contiguous U residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905163", "l": "negative regulation of phagosome maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0055057", "l": "neuroblast division", "d": ["The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. 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"40.512832381734405", "identifiers": [{"i": "GO:0071705", "l": "nitrogen compound transport", "d": ["The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045224", "l": "positive regulation of CD4 production", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901598", "l": "(-)-pinoresinol metabolic process", "d": ["The chemical reactions and pathways involving (-)-pinoresinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007557", "l": "regulation of juvenile hormone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:2000379", "l": "positive regulation of reactive oxygen species metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010519", "l": "negative regulation of phospholipase activity", "d": ["Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0002759", "l": "regulation of antimicrobial humoral response", "d": ["Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007348", "l": "regulation of syncytial blastoderm mitotic cell cycle", "d": ["A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097745", "l": "mitochondrial tRNA 5'-end processing", "d": ["The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900935", "l": "regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0008354", "l": "germ cell migration", "d": ["The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006761", "l": "dihydrofolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061152", "l": "trachea submucosa development", "d": ["The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032874", "l": "positive regulation of stress-activated MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061150", "l": "renal system segmentation", "d": ["The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000549", "l": "positive regulation of dendritic cell dendrite assembly", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0046149", "l": "pigment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070223", "l": "sulfide oxidation, using sulfur dioxygenase", "d": ["A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905516", "l": "positive regulation of fertilization", "d": ["Any process that activates or increases the frequency, rate or extent of fertilization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0039014", "l": "cell differentiation involved in pronephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033693", "l": "neurofilament bundle assembly", "d": ["The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. 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Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035347", "l": "negative regulation of hypoxanthine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050845", "l": "teichuronic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019552", "l": "glutamate catabolic process via 2-hydroxyglutarate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.41723220320425", "identifiers": [{"i": "GO:0043935", "l": "sexual sporulation resulting in formation of a cellular spore", "d": ["The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0051319", "l": "G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019261", "l": "1,4-dichlorobenzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039691", "l": "double stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990830", "l": "cellular response to leukemia inhibitory factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0072202", "l": "cell differentiation involved in metanephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901034", "l": "regulation of L-glutamine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-glutamine import into cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031149", "l": "sorocarp stalk cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0110037", "l": "regulation of nematode male tail tip morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120117", "l": "T cell meandering migration", "d": ["The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032672", "l": "regulation of interleukin-3 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-3 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010779", "l": "meiotic DNA repair synthesis involved in meiotic gene conversion", "d": ["The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. 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The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0055006", "l": "cardiac cell development", "d": ["The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001815", "l": "positive regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904276", "l": "regulation of wax biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of wax biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000708", "l": "meiotic strand invasion", "d": ["The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0099039", "l": "sphingolipid translocation", "d": ["The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.342419411848184", "identifiers": [{"i": "GO:0019098", "l": "reproductive behavior", "d": ["The specific behavior of an organism that is associated with reproduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061084", "l": "negative regulation of protein refolding", "d": ["Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903857", "l": "negative regulation of cytokinin dehydrogenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050971", "l": "detection of mechanical stimulus involved in magnetoreception", "d": ["The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902091", "l": "negative regulation of fumagillin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071246", "l": "cellular response to chlorate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046329", "l": "negative regulation of JNK cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0042416", "l": "dopamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016562", "l": "protein import into peroxisome matrix, receptor recycling", "d": ["The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035983", "l": "response to trichostatin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001124", "l": "regulation of translational frameshifting", "d": ["Any process that modulates the frequency, rate or extent of translational frameshifting."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0032885", "l": "regulation of polysaccharide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018291", "l": "molybdenum incorporation into iron-sulfur cluster", "d": ["The incorporation of molybdenum into an iron-sulfur cluster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905765", "l": "negative regulation of protection from non-homologous end joining at telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006590", "l": "thyroid hormone generation", "d": ["The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. 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There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. 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Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002330", "l": "pre-B cell receptor expression", "d": ["The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.778307795632415", "identifiers": [{"i": "GO:0009889", "l": "regulation of biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900168", "l": "positive regulation of glial cell-derived neurotrophic factor production", "d": ["Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0032882", "l": "regulation of chitin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072681", "l": "fibronectin-dependent thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0050915", "l": "sensory perception of sour taste", "d": ["The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. 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The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900155", "l": "negative regulation of bone trabecula formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002010", "l": "excitation of vasomotor center by baroreceptor signaling", "d": ["The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:1900428", "l": "regulation of filamentous growth of a population of unicellular organisms", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072140", "l": "DCT cell development", "d": ["The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0042478", "l": "regulation of eye photoreceptor cell development", "d": ["Any process that modulates the frequency, rate or extent of eye photoreceptor development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048920", "l": "posterior lateral line neuromast primordium migration", "d": ["The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. 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The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0019577", "l": "aldaric acid metabolic process", "d": ["The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.340966656807453", "identifiers": [{"i": "GO:0008217", "l": "regulation of blood pressure", "d": ["Any process that modulates the force with which blood travels through the circulatory system. 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An example of this process is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0030540", "l": "female genitalia development", "d": ["The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060454", "l": "positive regulation of gastric acid secretion", "d": ["Any process that increases the rate frequency or extent of gastric secretion. 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Substances that are secreted include organic anions, ammonia, potassium and drugs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044485", "l": "envenomation resulting in fibrinogenolysis in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036460", "l": "cellular response to cell envelope stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045069", "l": "regulation of viral genome replication", "d": ["Any process that modulates the frequency, rate or extent of viral genome replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045773", "l": "positive regulation of axon extension", "d": ["Any process that activates or increases the frequency, rate or extent of axon extension."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019677", "l": "NAD catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036530", "l": "protein deglycation, methylglyoxal removal", "d": ["The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.573157016390176", "identifiers": [{"i": "GO:0016485", "l": "protein processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. 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Mating types are the equivalent in microorganisms of the sexes in higher organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018884", "l": "carbazole metabolic process", "d": ["The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034149", "l": "positive regulation of toll-like receptor 5 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035346", "l": "positive regulation of hypoxanthine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048715", "l": "negative regulation of oligodendrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000857", "l": "positive regulation of mineralocorticoid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000949", "l": "aromatic amino acid family catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. 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Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038101", "l": "sequestering of nodal from receptor via nodal binding", "d": ["Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904552", "l": "regulation of chemotaxis to arachidonic acid", "d": ["Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903331", "l": "positive regulation of iron-sulfur cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:2000896", "l": "amylopectin metabolic process", "d": ["The chemical reactions and pathways involving an amylopectin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032498", "l": "detection of muramyl dipeptide", "d": ["The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0042177", "l": "negative regulation of protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021850", "l": "subpallium glioblast cell division", "d": ["The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900802", "l": "cspyrone B1 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cspyrone B1."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019050", "l": "suppression by virus of host apoptotic process", "d": ["A process in which a virus gene product suppresses host apoptosis, leading to a decrease in the frequency, rate or extent of apoptosis in the host cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052543", "l": "callose deposition in cell wall", "d": ["Any process in which callose is transported to, and/or maintained in, the cell wall. 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They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048928", "l": "posterior lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:1900047", "l": "negative regulation of hemostasis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033075", "l": "isoquinoline alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036368", "l": "cone photoresponse recovery", "d": ["The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. 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Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022019", "l": "dorsal lateral ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.026622328051275", "identifiers": [{"i": "GO:0072698", "l": "protein localization to microtubule cytoskeleton", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015707", "l": "nitrite transport", "d": ["The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071688", "l": "striated muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045737", "l": "positive regulation of cyclin-dependent protein serine/threonine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of CDK activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000752", "l": "regulation of glucosylceramide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061104", "l": "adrenal chromaffin cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. 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This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071034", "l": "CUT catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903856", "l": "regulation of cytokinin dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "51.567750632495624", "identifiers": [{"i": "GO:0006793", "l": "phosphorus metabolic process", "d": ["The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900677", "l": "positive regulation of F-9775B biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903427", "l": "negative regulation of reactive oxygen species biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:0039531", "l": "regulation of cytoplasmic pattern recognition receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a cytoplasmic pattern recognition receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046596", "l": "regulation of viral entry into host cell", "d": ["Any process that modulates the frequency, rate or extent of the viral entry into the host cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072737", "l": "response to diamide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048065", "l": "male courtship behavior, veined wing extension", "d": ["The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010249", "l": "auxin conjugate metabolic process", "d": ["The chemical reactions and pathways involving auxin conjugates, a bound form of auxin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061048", "l": "negative regulation of branching involved in lung morphogenesis", "d": ["Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060576", "l": "intestinal epithelial cell development", "d": ["The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0008347", "l": "glial cell migration", "d": ["The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000570", "l": "positive regulation of T-helper 2 cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0072109", "l": "glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. 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physiological ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901323", "l": "response to erythromycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141011", "l": "siRNA-mediated retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a siRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.301331245594", "identifiers": [{"i": "GO:0008285", "l": "negative regulation of cell population proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "50.871943873166877", "identifiers": [{"i": "GO:0001501", "l": "skeletal system development", "d": ["The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. 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Adipose tissue is specialized tissue that is used to store fat."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021639", "l": "trochlear nerve morphogenesis", "d": ["The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097737", "l": "acquisition of mycelium reproductive competence", "d": ["A maturation process by which an organism acquires the ability to reproduce. 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The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903702", "l": "esophagus development", "d": ["The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0034694", "l": "response to prostaglandin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903661", "l": "positive regulation of complement-dependent cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.300618254768168", "identifiers": [{"i": "GO:0060986", "l": "endocrine hormone secretion", "d": ["The regulated release of a hormone into the circulatory system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106210", "l": "culmorin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032712", "l": "negative regulation of interleukin-3 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085019", "l": "formation of tubovesicular network for nutrient acquisition", "d": ["The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. 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Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141134", "l": "symbiont-mediated activation of host signal transduction pathway via agonism of host cell surface receptor", "d": ["A process in which a symbiont subverts a signal transduction pathway in the host organism by binding to and enhancing the activation of the receptor of the pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0045466", "l": "R7 cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.866383925293761", "identifiers": [{"i": "GO:0043270", "l": "positive regulation of monoatomic ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051886", "l": "negative regulation of timing of anagen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0010561", "l": "negative regulation of glycoprotein biosynthetic process", "d": ["Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902997", "l": "negative regulation of neurofibrillary tangle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072125", "l": "negative regulation of glomerular mesangial cell proliferation", "d": ["Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061816", "l": "proteaphagy", "d": ["The selective degradation of proteasomes by macroautophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033089", "l": "positive regulation of T cell differentiation in thymus", "d": ["Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031337", "l": "positive regulation of sulfur amino acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033348", "l": "tetrose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060034", "l": "notochord cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. 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The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048213", "l": "Golgi vesicle prefusion complex stabilization", "d": ["The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035096", "l": "larval midgut cell programmed cell death", "d": ["The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0072699", "l": "protein localization to cortical microtubule cytoskeleton", "d": ["A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072195", "l": "kidney smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042899", "l": "arabinan transmembrane transport", "d": ["The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045748", "l": "positive regulation of R8 cell spacing in compound eye", "d": ["Any process that activates or enforces the correct R8 cell spacing in a compound eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007058", "l": "spindle assembly involved in female meiosis II", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035294", "l": "determination of wing disc primordium", "d": ["Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000435", "l": "positive regulation of transcription from RNA polymerase II promoter by galactose", "d": ["Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000390", "l": "negative regulation of neutrophil extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0090177", "l": "establishment of planar polarity involved in neural tube closure", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904787", "l": "positive regulation of asymmetric protein localization involved in cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000720", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048358", "l": "mucilage pectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the pectin component of mucilage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097326", "l": "melanocyte adhesion", "d": ["The attachment of a melanocyte to another cell via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070495", "l": "negative regulation of thrombin-activated receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000986", "l": "negative regulation of behavioral fear response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060483", "l": "lobar bronchus mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904033", "l": "negative regulation of t-SNARE clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045040", "l": "protein insertion into mitochondrial outer membrane", "d": ["The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019715", "l": "peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid", "d": ["The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0061136", "l": "regulation of proteasomal protein catabolic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048727", "l": "posterior cibarial plate development", "d": ["The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.796139606449842", "identifiers": [{"i": "GO:0045926", "l": "negative regulation of growth", "d": ["Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009833", "l": "plant-type primary cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. 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Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090687", "l": "activation of meiosis I spindle assembly checkpoint", "d": ["Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002878", "l": "negative regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045710", "l": "negative regulation of larval salivary gland boundary specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.314050959231352", "identifiers": [{"i": "GO:0010981", "l": "regulation of cell wall macromolecule metabolic process", "d": ["Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. 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between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0008045", "l": "motor neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903903", "l": "regulation of establishment of T cell polarity", "d": ["Any process that modulates the frequency, rate or extent of establishment of T cell polarity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051106", "l": "positive regulation of DNA ligation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken 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["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0007598", "l": "blood coagulation, extrinsic pathway", "d": ["A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044514", "l": "envenomation resulting in positive regulation of G protein-coupled receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", 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"t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903081", "l": "negative regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001930", "l": "positive regulation of exocyst assembly", "d": ["Any process that increases the rate or extent of exocyst assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006789", "l": "bilirubin conjugation", "d": ["The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0000753", "l": "cell 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Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048105", "l": "establishment of body hair planar orientation", "d": ["Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090017", "l": "anterior neural plate formation", "d": ["The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046443", "l": "FAD metabolic process", "d": ["The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904421", "l": "response to D-galactosamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1990182", "l": "exosomal secretion", "d": ["The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0007563", "l": "regulation of eclosion", "d": ["Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010044", "l": "response to aluminum ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015856", "l": "cytosine transport", "d": ["The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1990066", "l": "energy quenching", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060138", "l": "fetal process involved in parturition", "d": ["A reproductive process occurring in the embryo that results in birth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018966", "l": "styrene metabolic process", "d": ["The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. 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A fungal sorus is a spore containing structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002915", "l": "negative regulation of central B cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016256", "l": "N-glycan processing to lysosome", "d": ["The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903407", "l": "negative regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:1901071", "l": "glucosamine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901202", "l": "negative regulation of extracellular matrix assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0000079", "l": "regulation of cyclin-dependent protein serine/threonine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002615", "l": "positive regulation of monocyte antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031077", "l": "post-embryonic camera-type eye development", "d": ["The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016543", "l": "male courtship behavior, orientation prior to leg tapping and wing vibration", "d": ["The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010509", "l": "intracellular polyamine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of polyamine within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903454", "l": "regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904254", "l": "regulation of iron ion transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990116", "l": "ribosome-associated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. 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This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090188", "l": "negative regulation of pancreatic juice secretion", "d": ["Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003219", "l": "cardiac right ventricle formation", "d": ["The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0014036", "l": "neural crest cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035015", "l": "elongation of arista core", "d": ["The increase in length of the aristal core. 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A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021972", "l": "corticospinal neuron axon guidance through spinal cord", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0018200", "l": "peptidyl-glutamic acid modification", "d": ["The modification of peptidyl-glutamic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071452", "l": "cellular response to singlet oxygen", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. 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Many apocarotenoids are biologically important e.g. retinal and abscisic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009762", "l": "NADP-malic enzyme C4 photosynthesis", "d": ["The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061960", "l": "regulation of heme oxygenase activity", "d": ["Any process that modulates the frequency, or rate of heme oxygenase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0007593", "l": "chitin-based cuticle sclerotization", "d": ["The process of hardening of a chitin-based cuticle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905510", "l": "negative regulation of myosin II filament assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018220", "l": "peptidyl-threonine palmitoylation", "d": ["The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051683", "l": "establishment of Golgi localization", "d": ["The directed movement of the Golgi to a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900563", "l": "dehydroaustinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dehydroaustinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021597", "l": "central nervous system structural organization", "d": ["The process that contributes to the act of creating the structural organization of the central nervous system structure. 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The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0008593", "l": "regulation of Notch signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the Notch signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033526", "l": "tetrapyrrole biosynthetic process from glutamate", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.726079367374183", "identifiers": [{"i": "GO:0030850", "l": "prostate gland development", "d": ["The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. 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Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900761", "l": "averantin metabolic process", "d": ["The chemical reactions and pathways involving averantin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002936", "l": "bradykinin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0034227", "l": "tRNA thio-modification", "d": ["The addition a sulfur atom to a nucleotide in a tRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.432745995597372", "identifiers": [{"i": "GO:0048438", "l": "floral whorl development", "d": ["The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. 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This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0061984", "l": "catabolite repression", "d": ["A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900160", "l": "plastid chromosome packaging", "d": ["A process in which plastidial DNA and associated proteins organize into a compact, orderly structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0033076", "l": "isoquinoline alkaloid metabolic process", "d": ["The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050946", "l": "positive regulation of xanthophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of xanthophore differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034473", "l": "U1 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U1 snRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009606", "l": "tropism", "d": ["The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0015699", "l": "antimonite transport", "d": ["The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090717", "l": "adaptive immune memory response involving T cells and B cells", "d": ["An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.874891891299569", "identifiers": [{"i": "GO:0031424", "l": "keratinization", "d": ["The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032876", "l": "negative regulation of DNA endoreduplication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0016143", "l": "S-glycoside metabolic process", "d": ["The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034288", "l": "detection of disaccharide stimulus", "d": ["The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060579", "l": "ventral spinal cord interneuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903940", "l": "negative regulation of TORC2 signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018425", "l": "O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060958", "l": "endocardial cell development", "d": ["The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018971", "l": "anaerobic toluene metabolic process", "d": ["The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0062224", "l": "positive regulation of somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of somatic muscle development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905662", "l": "negative regulation of telomerase RNA reverse transcriptase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990656", "l": "t-SNARE clustering", "d": ["The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003168", "l": "Purkinje myocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). 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This is distinct from maintenance of cellular homeostasis, which occurs within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904021", "l": "negative regulation of G protein-coupled receptor internalization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904482", "l": "cellular response to tetrahydrofolate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905175", "l": "negative regulation of vascular associated smooth muscle cell dedifferentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003294", "l": "atrial ventricular junction remodeling", "d": ["The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903178", "l": "positive regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045057", "l": "cisternal progression", "d": ["The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019499", "l": "cyanide metabolic process", "d": ["The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. 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This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071449", "l": "cellular response to lipid hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019939", "l": "peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:2000214", "l": "regulation of proline metabolic process", "d": ["Any process that modulates the frequency, rate or extent of proline metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0014887", "l": "cardiac muscle adaptation", "d": ["The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. 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or extent of monocyte aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032343", "l": "aldosterone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0007442", "l": "hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0098514", "l": "detection of high humidity stimulus involved in sensory perception", "d": ["The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090446", "l": "negative regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903133", "l": "negative regulation of tube lumen cavitation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060514", "l": "prostate induction", "d": ["The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the 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"biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000408", "l": "negative regulation of T cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901819", "l": "alpha-zeacarotene metabolic process", "d": ["The chemical reactions and pathways involving alpha-zeacarotene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903258", "l": "sorbose import across plasma membrane", "d": ["The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060751", "l": "branch elongation involved in mammary gland duct branching", "d": ["The 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Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. 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Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900765", "l": "emericellin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902599", "l": "sulfathiazole transmembrane transport", "d": ["The directed movement of sulfathiazole across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:1904238", "l": "pericyte cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903593", "l": "regulation of histamine secretion by mast cell", "d": ["Any process that modulates the frequency, rate or extent of histamine secretion by mast cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000844", "l": "negative regulation of testosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.475256590178944", "identifiers": [{"i": "GO:0006956", "l": "complement activation", "d": ["Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0033275", "l": "actin-myosin filament sliding", "d": ["The sliding movement of actin thin filaments and myosin thick filaments past each other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0071362", "l": "cellular response to ether", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071965", "l": "multicellular organismal locomotion", "d": ["Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0050990", "l": "N-terminal protein amino acid carbamoylation", "d": ["The carbamoylation of the N-terminal amino acid of proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072748", "l": "cellular response to tacrolimus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905400", "l": "negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904800", "l": "negative regulation of neuron remodeling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032762", "l": "mast cell cytokine production", "d": ["Any process that contributes to cytokine production by a mast cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032645", "l": "regulation of granulocyte macrophage colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.925319206868252", "identifiers": [{"i": "GO:0044786", "l": "cell cycle DNA replication", "d": ["The DNA-dependent DNA replication that takes place as part of the cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.375074843138819", "identifiers": [{"i": "GO:0097746", "l": "blood vessel diameter maintenance", "d": ["Any process that modulates the diameter of blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903620", "l": "positive regulation of transdifferentiation", "d": ["Any process that activates or increases the frequency, rate or extent of transdifferentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002355", "l": "detection of tumor cell", "d": ["The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033368", "l": "protease localization to mast cell secretory granule", "d": ["Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106136", "l": "lectin-induced modified bacterial internalization", "d": ["The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048341", "l": "paraxial mesoderm formation", "d": ["The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902092", "l": "positive regulation of fumagillin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060588", "l": "negative regulation of lipoprotein lipid oxidation", "d": ["Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. 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The renal cortex is the outer region of the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0046755", "l": "viral budding", "d": ["A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0071574", "l": "protein localization to medial cortex", "d": ["A process in which a protein is transported to, or maintained in, the medial cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097744", "l": "renal urate salt excretion", "d": ["The elimination of urate salt or uric acid from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0071635", "l": "negative regulation of transforming growth factor beta production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075035", "l": "appressorium maturation", "d": ["The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900893", "l": "regulation of tridecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tridecane metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0098974", "l": "postsynaptic actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "51.044093090649604", "identifiers": [{"i": "GO:0008104", "l": "protein localization", "d": ["Any process in which a protein is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044407", "l": "single-species biofilm formation in or on host organism", "d": ["A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051764", "l": "actin crosslink formation", "d": ["The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. 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Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002523", "l": "leukocyte migration involved in inflammatory response", "d": ["The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002270", "l": "plasmacytoid dendritic cell activation", "d": ["A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070247", "l": "regulation of natural killer cell apoptotic process", "d": ["Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.888056135543266", "identifiers": [{"i": "GO:0007599", "l": "hemostasis", "d": ["The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046960", "l": "sensitization", "d": ["An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060392", "l": "negative regulation of SMAD protein signal transduction", "d": ["Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903183", "l": "negative regulation of SUMO transferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903951", "l": "positive regulation of AV node cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of AV node cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061381", "l": "cell migration in diencephalon", "d": ["The orderly movement of a cell that will reside in the diencephalon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046158", "l": "ocellus pigment metabolic process", "d": ["The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046339", "l": "diacylglycerol metabolic process", "d": ["The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035775", "l": "pronephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the pronephric glomerulus are generated and organized. 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The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072150", "l": "juxtaglomerulus cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021804", "l": "negative regulation of cell adhesion in ventricular zone", "d": ["The process that results in the loss of attachments of a cell in the ventricular zone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0033046", "l": "negative regulation of sister chromatid segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071399", "l": "cellular response to linoleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903862", "l": "positive regulation of oxidative phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071594", "l": "thymocyte aggregation", "d": ["The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098529", "l": "neuromuscular junction development, skeletal muscle fiber", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0110018", "l": "cap-independent translational initiation of circular RNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904864", "l": "negative regulation of beta-catenin-TCF complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003243", "l": "circumferential growth involved in left ventricle morphogenesis", "d": ["The morphogenetic growth in which the left ventricle grows expanding its external boundary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000303", "l": "regulation of ceramide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000822", "l": "regulation of behavioral fear response", "d": ["Any process that modulates the frequency, rate or extent of behavioral fear response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085014", "l": "dormancy entry of symbiont in host", "d": ["Entry into a dormant state of the symbiont within the host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051085", "l": "chaperone cofactor-dependent protein refolding", "d": ["The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. 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Such vesicles include COPI-coated transport vesicles involved in retrograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010186", "l": "positive regulation of cellular defense response", "d": ["Any process that activates or increases the frequency, rate or extent of cellular defense response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0033484", "l": "intracellular nitric oxide homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060518", "l": "cell migration involved in prostatic bud elongation", "d": ["The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044593", "l": "iron-sulfur-molybdenum cofactor assembly", "d": ["The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019697", "l": "L-xylitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. 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"identifiers": [{"i": "GO:0045656", "l": "negative regulation of monocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0099628", "l": "neurotransmitter receptor diffusion trapping", "d": ["The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035047", "l": "centrosomal and pronuclear rotation", "d": ["The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048457", "l": "floral whorl 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Excludes the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007473", "l": "wing disc proximal/distal pattern formation", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001507", "l": "acetylcholine catabolic process in synaptic cleft", "d": ["The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035573", "l": "N-terminal peptidyl-serine trimethylation", "d": ["The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051877", "l": "pigment granule aggregation in cell center", "d": ["The directed movement of dispersed pigment granules towards the center of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090616", "l": "mitochondrial mRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051005", "l": "negative regulation of lipoprotein lipase activity", "d": ["Any process that stops or reduces the activity of the enzyme lipoprotein lipase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003350", "l": "pulmonary myocardium development", "d": ["The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. 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The bud elongates and branches to give rise to the ureter and kidney collecting tubules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045670", "l": "regulation of osteoclast differentiation", "d": ["Any process that modulates the frequency, rate or extent of osteoclast differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905325", "l": "regulation of meiosis I spindle assembly checkpoint", "d": ["Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903712", "l": "cysteine transmembrane transport", "d": ["The directed movement of cysteine across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000872", "l": "positive regulation of progesterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of progesterone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061030", "l": "epithelial cell differentiation involved in mammary gland alveolus development", "d": ["The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900510", "l": "negative regulation of pentose catabolic process to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0034094", "l": "regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990559", "l": "mitochondrial coenzyme A transmembrane transport", "d": ["The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901784", "l": "p-cresol metabolic process", "d": ["The chemical reactions and pathways involving p-cresol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0050748", "l": "negative regulation of lipoprotein metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0034453", "l": "microtubule anchoring", "d": ["Any process in which a microtubule is maintained in a specific location in a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016260", "l": "selenocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010070", "l": "zygote asymmetric cell division", "d": ["The division of the zygote into two daughter cells that will adopt developmentally distinct potentials."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0007528", "l": "neuromuscular junction development", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141010", "l": "retrotransposon silencing by RNA-directed DNA methylation", "d": ["A retrotransposon silencing mechanism mediated by RNA-directed DNA methylation. 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They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140116", "l": "fluoride export across plasma membrane", "d": ["The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060368", "l": "regulation of Fc receptor mediated stimulatory signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway.."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902907", "l": "proteasome storage granule disassembly", "d": ["The disaggregation of a proteasome storage granule into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.394554035919811", "identifiers": [{"i": "GO:0016052", "l": "carbohydrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043477", "l": "pigment biosynthetic process involved in pigment accumulation", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0051664", "l": "nuclear pore localization", "d": ["Any process in which nuclear pores are transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061036", "l": "positive regulation of cartilage development", "d": ["Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. 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Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901495", "l": "negative regulation of cysteine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.402634366777022", "identifiers": [{"i": "GO:0006939", "l": "smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.314050959231352", "identifiers": [{"i": "GO:0043050", "l": "nematode pharyngeal pumping", "d": ["The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021791", "l": "chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme", "d": ["The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046586", "l": "regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.40455714802998", "identifiers": [{"i": "GO:0034765", "l": "regulation of monoatomic ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0035195", "l": "miRNA-mediated post-transcriptional gene silencing", "d": ["A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010752", "l": "regulation of cGMP-mediated signaling", "d": ["Any process that modulates the rate, frequency or extent of cGMP-mediated signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901415", "l": "positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905211", "l": "negative regulation of fibroblast chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060741", "l": "prostate gland stromal morphogenesis", "d": ["The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900067", "l": "regulation of cellular response to alkaline pH", "d": ["Any process that modulates the frequency, rate or extent of cellular response to alkalinity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015841", "l": "chromaffin granule amine transport", "d": ["The directed movement of amines into, out of or within chromaffin granules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090519", "l": "anoxia protection", "d": ["Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902042", "l": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090223", "l": "chromatin-templated microtubule nucleation", "d": ["The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010497", "l": "plasmodesmata-mediated intercellular transport", "d": ["The movement of substances between cells via plasmodesmata. 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Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.406182672343874", "identifiers": [{"i": "GO:0050907", "l": "detection of chemical stimulus involved in sensory perception", "d": ["The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901957", "l": "regulation of cutin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cutin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000735", "l": "removal of nonhomologous ends", "d": ["The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072040", "l": "negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0120302", "l": "background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0000394", "l": "RNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034351", "l": "negative regulation of glial cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019122", "l": "peptidyl-D-alanine racemization", "d": ["The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904139", "l": "regulation of microglial cell migration", "d": ["Any process that modulates the frequency, rate or extent of microglial cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900178", "l": "negative regulation of aflatoxin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902822", "l": "regulation of late endosome to lysosome transport", "d": ["Any process that modulates the frequency, rate or extent of late endosome to lysosome transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901412", "l": "positive regulation of tetrapyrrole biosynthetic process from glutamate", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0046503", "l": "glycerolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0010624", "l": "regulation of Schwann cell proliferation", "d": ["Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. 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Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties. Occurs in non-enveloped prokaryotic viruses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0003365", "l": "establishment of cell polarity involved in ameboidal cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046841", "l": "trisporic acid metabolic process", "d": ["The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140067", "l": "peptidyl-lysine butyrylation", "d": ["The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061940", "l": "regulation of c-di-GMP signaling", "d": ["Any process that modulates the rate frequency or extent of c-di-GMP signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000713", "l": "meiotic heteroduplex formation", "d": ["During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900130", "l": "regulation of lipid binding", "d": ["Any process that modulates the frequency, rate or extent of lipid binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030511", "l": "positive regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900217", "l": "regulation of apoptotic process involved in metanephric nephron tubule development", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900383", "l": "regulation of synaptic plasticity by receptor localization to synapse", "d": ["Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904634", "l": "negative regulation of podocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0009260", "l": "ribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:2000762", "l": "regulation of phenylpropanoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001561", "l": "fatty acid alpha-oxidation", "d": ["A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900812", "l": "helvolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of helvolic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010932", "l": "regulation of macrophage tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of macrophage tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097288", "l": "7-cyano-7-deazaguanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071259", "l": "cellular response to magnetism", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0051438", "l": "regulation of ubiquitin-protein transferase activity", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin transferase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071332", "l": "cellular response to fructose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0007465", "l": "R7 cell fate commitment", "d": ["The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0010522", "l": "regulation of calcium ion transport into cytosol", "d": ["Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050669", "l": "negative regulation of homocysteine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060979", "l": "vasculogenesis involved in coronary vascular morphogenesis", "d": ["The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051417", "l": "microtubule nucleation by spindle pole body", "d": ["The 'de novo' formation of a microtubule, mediated by the spindle pole body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061365", "l": "positive regulation of triglyceride lipase activity", "d": ["Any process that increases the activity of triglyceride lipase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006648", "l": "dihydrosphingosine-1-P pathway", "d": ["A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010079", "l": "maintenance of vegetative meristem identity", "d": ["The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006219", "l": "deoxyuridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021622", "l": "oculomotor nerve morphogenesis", "d": ["The process in which the anatomical structure of the oculomotor nerve is generated and organized. 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The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062212", "l": "regulation of mitotic DNA replication initiation from early origin", "d": ["Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019505", "l": "resorcinol metabolic process", "d": ["The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042865", "l": "pyochelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035090", "l": "maintenance of apical/basal cell polarity", "d": ["Retaining the established polarization of a cell along its apical/basal axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900969", "l": "negative regulation of sarcinapterin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0031671", "l": "primary cell septum biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:1905476", "l": "negative regulation of protein localization to membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007374", "l": "posterior midgut invagination", "d": ["Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003024", "l": "baroreceptor detection of decreased arterial stretch", "d": ["The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0007316", "l": "pole plasm RNA localization", "d": ["Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0071853", "l": "fungal-type cell wall disassembly", "d": ["A cellular process that results in the breakdown of a fungal-type cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0120032", "l": "regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001016", "l": "positive regulation of skeletal muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106384", "l": "dGMP salvage", "d": ["Any process which produces a dGMP from derivatives of it, without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000396", "l": "negative regulation of ubiquitin-dependent endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900221", "l": "regulation of amyloid-beta clearance", "d": ["Any process that modulates the frequency, rate or extent of amyloid-beta clearance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090709", "l": "regulation of timing of plant organ formation", "d": ["Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046157", "l": "siroheme catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097309", "l": "cap1 mRNA methylation", "d": ["Methylation of the ribose of the first nucleotide of a 5'-capped mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902089", "l": "cell wall polysaccharide catabolic process involved in lateral root development", "d": ["Any cell wall polysaccharide catabolic process that is involved in lateral root development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061259", "l": "mesonephric glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0060039", "l": "pericardium development", "d": ["The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:0000917", "l": "division septum assembly", "d": ["The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. 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For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000789", "l": "positive regulation of venous endothelial cell fate commitment", "d": ["Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034461", "l": "uropod retraction", "d": ["The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0016095", "l": "polyprenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061721", "l": "6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0052094", "l": "formation of haustorium for nutrient acquisition", "d": ["The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097172", "l": "N-acetylmuramic acid metabolic process", "d": ["The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901194", "l": "negative regulation of formation of translation preinitiation complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048784", "l": "pigment biosynthetic process involved in pigment granule maturation", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903048", "l": "regulation of acetylcholine-gated cation channel activity", "d": ["Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009222", "l": "pyrimidine ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072029", "l": "long nephron development", "d": ["The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018404", "l": "protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901154", "l": "paromomycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of paromomycin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901868", "l": "ecgonine methyl ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061233", "l": "mesonephric glomerular basement membrane development", "d": ["The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035089", "l": "establishment of apical/basal cell polarity", "d": ["The specification and formation of the polarity of a cell along its apical/basal axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048824", "l": "pigment cell precursor differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072597", "l": "maintenance of protein location in chloroplast", "d": ["Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0031110", "l": "regulation of microtubule polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048104", "l": "establishment of body hair or bristle planar orientation", "d": ["Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046425", "l": "regulation of receptor signaling pathway via JAK-STAT", "d": ["Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:1990822", "l": "basic amino acid transmembrane transport", "d": ["The directed movement of basic amino acids from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0098653", "l": "centromere clustering", "d": ["The process by which centromeres/kinetochores become localized to clusters."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.791380143804204", "identifiers": [{"i": "GO:0002460", "l": "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003026", "l": "regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback", "d": ["The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1901607", "l": "alpha-amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alpha-amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062191", "l": "galactoxylomannan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. 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The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900659", "l": "negative regulation of emericellamide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0097300", "l": "programmed necrotic cell death", "d": ["A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072682", "l": "eosinophil extravasation", "d": ["The migration of an eosinophil from the blood vessels into the surrounding tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050970", "l": "detection of electrical stimulus involved in magnetoreception", "d": ["The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000447", "l": "negative regulation of macrophage migration inhibitory factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010603", "l": "regulation of cytoplasmic mRNA processing body assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006016", "l": "2-deoxyribose 1-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002733", "l": "regulation of myeloid dendritic cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0072578", "l": "neurotransmitter-gated ion channel clustering", "d": ["The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003047", "l": "regulation of systemic arterial blood pressure by epinephrine", "d": ["The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0044843", "l": "cell cycle G1/S phase transition", "d": ["The cell cycle process by which a cell in G1 phase commits to S phase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140084", "l": "sexual macrocyst formation", "d": ["The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:2000197", "l": "regulation of ribonucleoprotein complex localization", "d": ["Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000836", "l": "positive regulation of androgen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of androgen secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900978", "l": "negative regulation of tatiopterin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141044", "l": "epigenetic programming in the endosperm", "d": ["The global programming of epigenetic modifications following binucleate central cell fertilization. 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Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope. Occurs in non-enveloped prokaryotic viruses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905694", "l": "negative regulation of phosphatidic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904143", "l": "positive regulation of carotenoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045852", "l": "pH elevation", "d": ["Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0006722", "l": "triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003210", "l": "cardiac atrium formation", "d": ["The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.17550784065299", "identifiers": [{"i": "GO:0002250", "l": "adaptive immune response", "d": ["An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044866", "l": "modulation by host of viral exo-alpha-sialidase activity", "d": ["The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002546", "l": "negative regulation of tissue kallikrein-kinin cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009912", "l": "auditory receptor cell fate commitment", "d": ["The process in which the cellular identity of auditory hair cells is acquired and determined."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0010965", "l": "regulation of mitotic sister chromatid separation", "d": ["Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. 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In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0034091", "l": "regulation of maintenance of sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001915", "l": "negative regulation of T cell mediated cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072168", "l": "specification of anterior mesonephric tubule identity", "d": ["The process in which the tubules of the anterior mesonephros acquire their identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019084", "l": "middle viral transcription", "d": ["The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0006289", "l": "nucleotide-excision repair", "d": ["A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. 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Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905767", "l": "regulation of double-stranded telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.078697315966167", "identifiers": [{"i": "GO:0046474", "l": "glycerophospholipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0016099", "l": "monoterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051071", "l": "4,6-pyruvylated galactose residue metabolic process", "d": ["The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.475256590178944", "identifiers": [{"i": "GO:0050867", "l": "positive regulation of cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034242", "l": "negative regulation of syncytium formation by plasma membrane fusion", "d": ["Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000485", "l": "cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019449", "l": "L-cysteine catabolic process to hypotaurine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905171", "l": "positive regulation of protein localization to phagocytic vesicle", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905814", "l": "positive regulation of motor neuron axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1903557", "l": "positive regulation of tumor necrosis factor superfamily cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071506", "l": "cellular response to mycophenolic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0035932", "l": "aldosterone secretion", "d": ["The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051974", "l": "negative regulation of telomerase activity", "d": ["Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002783", "l": "antifungal peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antifungal peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903233", "l": "regulation of calcium ion-dependent exocytosis of neurotransmitter", "d": ["Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0032241", "l": "positive regulation of nucleobase-containing compound transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.974037860983486", "identifiers": [{"i": "GO:0042692", "l": "muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a muscle cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030949", "l": "positive regulation of vascular endothelial growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0061343", "l": "cell adhesion involved in heart morphogenesis", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009175", "l": "pyrimidine ribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000508", "l": "regulation of dendritic cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.46281596354936", "identifiers": [{"i": "GO:0045580", "l": "regulation of T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061374", "l": "mammillothalamic axonal tract development", "d": ["The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046016", "l": "positive regulation of transcription by glucose", "d": ["Any process involving glucose that activates or increases the rate of transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021894", "l": "cerebral cortex GABAergic interneuron development", "d": ["The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052151", "l": "symbiont-mediated activation of host apoptosis", "d": ["A process in which a symbiont gene product activates host apoptosis, leading to an increase in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.774074961591239", "identifiers": [{"i": "GO:0030336", "l": "negative regulation of cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060134", "l": "prepulse inhibition", "d": ["The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019381", "l": "atrazine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051554", "l": "flavonol metabolic process", "d": ["The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010423", "l": "negative regulation of brassinosteroid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905170", "l": "negative regulation of protein localization to phagocytic vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990863", "l": "acinar cell proliferation", "d": ["The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0080021", "l": "response to benzoic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0008216", "l": "spermidine metabolic process", "d": ["The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097012", "l": "response to granulocyte macrophage colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003034", "l": "detection of increased carbon dioxide by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033610", "l": "oxalate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090372", "l": "positive regulation of glycerol transport", "d": ["Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0099113", "l": "negative regulation of presynaptic cytosolic calcium concentration", "d": ["Any process that decreases the concentration of calcium ions in the presynaptic cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042778", "l": "tRNA end turnover", "d": ["The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:2000966", "l": "regulation of cell wall polysaccharide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036034", "l": "mediator complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071946", "l": "cis-acting DNA replication termination", "d": ["A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021849", "l": "neuroblast division in subventricular zone", "d": ["The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990579", "l": "peptidyl-serine trans-autophosphorylation", "d": ["The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905395", "l": "response to flavonoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0086004", "l": "regulation of cardiac muscle cell contraction", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071283", "l": "cellular response to iron(III) ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.180713427975022", "identifiers": [{"i": "GO:0051225", "l": "spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070935", "l": "3'-UTR-mediated mRNA stabilization", "d": ["An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:1901983", "l": "regulation of protein acetylation", "d": ["Any process that modulates the frequency, rate or extent of protein acetylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902239", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140547", "l": "acquisition of seed longevity", "d": ["The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0006612", "l": "protein targeting to membrane", "d": ["The process of directing proteins towards a membrane, usually using signals contained within the protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010667", "l": "negative regulation of cardiac muscle cell apoptotic process", "d": ["Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000984", "l": "negative regulation of ATP citrate synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010267", "l": "ta-siRNA processing", "d": ["A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060276", "l": "maintenance of stationary phase in response to toxin", "d": ["The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048914", "l": "myelination of anterior lateral line nerve axons", "d": ["The formation of compact myelin sheaths around the axons of the anterior lateral line nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019456", "l": "L-cysteine catabolic process via cystine, using cysteine transaminase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009939", "l": "positive regulation of gibberellic acid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010572", "l": "positive regulation of platelet activation", "d": ["Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045591", "l": "positive regulation of regulatory T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090737", "l": "telomere maintenance via telomere trimming", "d": ["A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990765", "l": "colon smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "50.438512521611244", "identifiers": [{"i": "GO:0006629", "l": "lipid metabolic process", "d": ["The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072700", "l": "response to bismuth", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006855", "l": "xenobiotic transmembrane transport", "d": ["The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046667", "l": "compound eye retinal cell programmed cell death", "d": ["Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903423", "l": "positive regulation of synaptic vesicle recycling", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150191", "l": "positive regulation of interleukin-32 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-32 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160073", "l": "Casparian strip assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Casparian strip, a region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071213", "l": "cellular response to 1-aminocyclopropane-1-carboxylic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0032185", "l": "septin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of 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"biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0050961", "l": "detection of temperature stimulus involved in sensory perception", "d": ["The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046008", "l": "regulation of female receptivity, post-mating", "d": ["Any process that modulates the receptiveness of a female to male advances subsequent to mating."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0040031", "l": "snRNA modification", "d": ["The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900260", "l": "negative 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Not all viruses mature after separation. 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It is a key intermediate in lipid and terpenoid biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.300132063293475", "identifiers": [{"i": "GO:0050910", "l": "detection of mechanical stimulus involved in sensory perception of sound", "d": ["The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902445", "l": "regulation of mitochondrial membrane permeability involved in programmed necrotic cell death", "d": ["Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046549", "l": "retinal cone cell development", "d": ["Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031161", "l": "phosphatidylinositol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009644", "l": "response to high light intensity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000829", "l": "negative regulation of parathyroid hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007174", "l": "epidermal growth factor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031367", "l": "N-terminal peptidyl-glutamine deamination", "d": ["The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902874", "l": "positive regulation of horizontal cell localization", "d": ["Any process that activates or increases the frequency, rate or extent of horizontal cell localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904435", "l": "regulation of transferrin receptor binding", "d": ["Any process that modulates the frequency, rate or extent of transferrin receptor binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000758", "l": "positive regulation of peptidyl-lysine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0043392", "l": "negative regulation of DNA binding", "d": ["Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061945", "l": "regulation of protein K48-linked ubiquitination", "d": ["Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071864", "l": "positive regulation of cell proliferation in bone marrow", "d": ["A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090618", "l": "DNA clamp unloading", "d": ["The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990058", "l": "fruit replum development", "d": ["The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050696", "l": "trichloroethylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905220", "l": "negative regulation of platelet formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0002190", "l": "cap-independent translational initiation", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006562", "l": "proline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097477", "l": "lateral motor column neuron migration", "d": ["The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140725", "l": "detoxification of free heme", "d": ["Any process that reduces or removes the toxicity of free heme. These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035001", "l": "dorsal trunk growth, open tracheal system", "d": ["Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904770", "l": "intramembranous bone morphogenesis", "d": ["The developmental process by which an intramembranous bone is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902946", "l": "protein localization to early endosome", "d": ["A process in which a protein is transported to, or maintained in, a location within an early endosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021638", "l": "trigeminal nerve formation", "d": ["The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0022038", "l": "corpus callosum development", "d": ["The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.239663535624402", "identifiers": [{"i": "GO:0070661", "l": "leukocyte proliferation", "d": ["The expansion of a leukocyte population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072221", "l": "metanephric distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048389", "l": "intermediate mesoderm development", "d": ["The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0072347", "l": "response to anesthetic", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1900151", "l": "regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.315929082021214", "identifiers": [{"i": "GO:0051231", "l": "spindle elongation", "d": ["The cell cycle process in which the distance is lengthened between poles of the spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0000821", "l": "regulation of arginine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902391", "l": "positive regulation of N-terminal peptidyl-serine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902234", "l": "positive regulation of positive thymic T cell selection", "d": ["Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.385242451594038", "identifiers": [{"i": "GO:0060216", "l": "definitive hemopoiesis", "d": ["A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900694", "l": "positive regulation of (+)-kotanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900540", "l": "fumonisin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fumonisin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019352", "l": "protoporphyrinogen IX biosynthetic process from glycine", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0016198", "l": "axon choice point recognition", "d": ["The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.169140273041734", "identifiers": [{"i": "GO:0031324", "l": "negative regulation of cellular metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061453", "l": "interstitial cell of Cajal differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. 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How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0086029", "l": "Purkinje myocyte to ventricular cardiac muscle cell signaling", "d": ["Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051623", "l": "positive regulation of norepinephrine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035751", "l": "regulation of lysosomal lumen pH", "d": ["Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000032", "l": "cell wall mannoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019667", "l": "anaerobic L-alanine catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042760", "l": "very long-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a very long-chain fatty acid. 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Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032595", "l": "B cell receptor transport within lipid bilayer", "d": ["The directed movement of a B cell receptor within a lipid bilayer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031025", "l": "equatorial microtubule organizing center disassembly", "d": ["The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070426", "l": "positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0018202", "l": "peptidyl-histidine modification", "d": ["The modification of peptidyl-histidine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902638", "l": "neural crest cell differentiation involved in parathyroid gland development", "d": ["Any neural crest cell differentiation that is involved in parathyroid gland development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904557", "l": "L-alanine transmembrane transport", "d": ["The directed movement of L-alanine across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0033151", "l": "V(D)J recombination", "d": ["The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.377167515423608", "identifiers": [{"i": "GO:0098609", "l": "cell-cell adhesion", "d": ["The attachment of one cell to another cell via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902081", "l": "negative regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0021595", "l": "rhombomere structural organization", "d": ["The process that contributes to the act of creating the structural organization of the rhombomere structure. 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Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903849", "l": "positive regulation of aorta morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of aorta morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903302", "l": "regulation of pyruvate kinase activity", "d": ["Any process that modulates the frequency, rate or extent of pyruvate kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050841", "l": "peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine", "d": ["The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016320", "l": "endoplasmic reticulum membrane fusion", "d": ["The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0070784", "l": "regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042187", "l": "p-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003003", "l": "follicular fluid formation in ovarian follicle antrum involved in fused antrum stage", "d": ["The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036114", "l": "medium-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. 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The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0051962", "l": "positive regulation of nervous system development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000780", "l": "negative regulation of double-strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030840", "l": "negative regulation of intermediate filament polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071502", "l": "cellular response to temperature stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071247", "l": "cellular response to chromate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0000423", "l": "mitophagy", "d": ["The selective autophagy process in which a mitochondrion is degraded by macroautophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0070949", "l": "regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000821", "l": "regulation of grooming behavior", "d": ["Any process that modulates the frequency, rate or extent of grooming behavior."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990768", "l": "gastric mucosal blood circulation", "d": ["The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.837498118084909", "identifiers": [{"i": "GO:0050962", "l": "detection of light stimulus involved in sensory perception", "d": ["The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051638", "l": "barbed-end actin filament uncapping", "d": ["The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046492", "l": "heme B metabolic process", "d": ["The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0021987", "l": "cerebral cortex development", "d": ["The progression of the cerebral cortex over time from its initial formation until its mature state. 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D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046487", "l": "glyoxylate metabolic process", "d": ["The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0034196", "l": "acylglycerol transport", "d": ["The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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The nipple is a part of the mammary gland that protrudes from the surface ectoderm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900515", "l": "regulation of xylose catabolic process to ethanol", "d": ["Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048764", "l": "trichoblast maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010129", "l": "anaerobic cyclohexane-1-carboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904438", "l": "regulation of iron ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900642", "l": "positive regulation of austinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043143", "l": "regulation of translation by machinery localization", "d": ["Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010630", "l": "regulation of transcription, start site selection", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000660", "l": "negative regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031587", "l": "positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072385", "l": "minus-end-directed organelle transport along microtubule", "d": ["The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. 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the formation of the neural placode."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150176", "l": "positive regulation of phosphatidylethanolamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035724", "l": "CD24 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904997", "l": "regulation of leukocyte adhesion to arterial endothelial cell", "d": ["Any process 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"t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045943", "l": "positive regulation of transcription by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.088320895280148", "identifiers": [{"i": "GO:2001233", "l": "regulation of apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905722", "l": "regulation of trypanothione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000381", "l": "regulation of alternative mRNA splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033689", "l": "negative regulation of osteoblast proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036153", "l": "triglyceride acyl-chain remodeling", "d": ["Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048818", "l": "positive regulation of hair follicle maturation", "d": ["Any process that 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Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051948", "l": "negative regulation of glutamate uptake involved in transmission of nerve impulse", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009195", "l": "pyrimidine ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0043475", "l": "pigment metabolic process involved in pigment accumulation", "d": ["The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002212", "l": "behavioral defense response to nematode", "d": ["A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018297", "l": "protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine", "d": ["The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048616", "l": "post-embryonic anterior midgut (ectodermal) morphogenesis", "d": ["The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007541", "l": "sex determination, primary response to X:A ratio", "d": ["The developmental process in which an organism interprets its X to autosomal chromosomal complement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905708", "l": "regulation of cell morphogenesis involved in conjugation with cellular fusion", "d": ["Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032786", "l": "positive regulation of DNA-templated transcription, elongation", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900554", "l": "asperfuranone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asperfuranone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050883", "l": "musculoskeletal movement, spinal reflex action", "d": ["Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. 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This process could involve several cycles of ATP hydrolysis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019453", "l": "L-cysteine catabolic process via cystine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055045", "l": "antipodal cell degeneration", "d": ["The process in which the antipodal cells undergo programmed cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000770", "l": "peptide pheromone export", "d": ["The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900285", "l": "regulation of cellotriose transport", "d": ["Any process that modulates the frequency, rate or extent of cellotriose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072739", "l": "response to anisomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106122", "l": "negative regulation of cobalamin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090117", "l": "endosome to lysosome transport of low-density lipoprotein particle", "d": ["The directed movement of low-density lipoprotein particle from endosomes to lysosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033141", "l": "positive regulation of peptidyl-serine phosphorylation of STAT protein", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031017", "l": "exocrine pancreas development", "d": ["The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. 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The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900026", "l": "positive regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0021957", "l": "corticospinal tract morphogenesis", "d": ["Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905913", "l": "negative regulation of calcium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046381", "l": "CMP-N-acetylneuraminate metabolic process", "d": ["The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045838", "l": "positive regulation of membrane potential", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:1903475", "l": "mitotic actomyosin contractile ring assembly", "d": ["Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.86759105459673", "identifiers": [{"i": "GO:0044093", "l": "positive regulation of molecular function", "d": ["Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903232", "l": "melanosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035348", "l": "acetyl-CoA transmembrane transport", "d": ["The process in which acetyl-CoA is transported across a membrane. 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It is a key intermediate in lipid and terpenoid biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072259", "l": "metanephric interstitial fibroblast development", "d": ["The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035221", "l": "genital disc pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035910", "l": "ascending aorta morphogenesis", "d": ["The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097070", "l": "ductus arteriosus closure", "d": ["The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075227", "l": "regulation of encysted zoospore germination", "d": ["Any process that modulates the frequency, rate or extent of an encysted zoospore germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060024", "l": "rhythmic synaptic transmission", "d": ["Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034144", "l": "negative regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0080036", "l": "regulation of cytokinin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of cytokinin signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010685", "l": "tetracyclic triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038098", "l": "sequestering of BMP from receptor via BMP binding", "d": ["Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090137", "l": "epithelial cell-cell adhesion involved in epithelium migration", "d": ["The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160057", "l": "plant endodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a plant endodermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900757", "l": "regulation of D-amino-acid oxidase activity", "d": ["Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0017009", "l": "protein-phycocyanobilin linkage", "d": ["The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000950", "l": "branched-chain amino acid catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0001700", "l": "embryonic development via the syncytial blastoderm", "d": ["The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051044", "l": "positive regulation of membrane protein ectodomain proteolysis", "d": ["Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032544", "l": "plastid translation", "d": ["The chemical reactions and pathways resulting in the formation of a protein in a plastid. 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Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0110113", "l": "positive regulation of lipid transporter activity", "d": ["Any process that increases the frequency, rate, or extent of lipid transporter activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.385242451594038", "identifiers": [{"i": "GO:0006644", "l": "phospholipid metabolic process", "d": ["The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902982", "l": "DNA strand elongation involved in premeiotic DNA replication", "d": ["Any DNA strand elongation involved in meiotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901234", "l": "positive regulation of convergent extension involved in axis elongation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019380", "l": "3-phenylpropionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042918", "l": "alkanesulfonate transport", "d": ["The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904891", "l": "positive regulation of excitatory synapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033381", "l": "establishment of granzyme B localization to T cell secretory granule", "d": ["The directed movement of the protease granzyme B to a location within a secretory granule in a T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.58909006025462", "identifiers": [{"i": "GO:0006418", "l": "tRNA aminoacylation for protein translation", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0002516", "l": "B cell deletion", "d": ["The apoptotic death of B cells which is part of B cell tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070714", "l": "RNA guanosine-uridine insertion", "d": ["The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035231", "l": "cytoneme assembly", "d": ["Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904832", "l": "negative regulation of removal of superoxide radicals", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046099", "l": "guanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051547", "l": "regulation of keratinocyte migration", "d": ["Any process that modulates the frequency, rate or extent of keratinocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019523", "l": "L-idonate metabolic process", "d": ["The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "51.970286409664951", "identifiers": [{"i": "GO:0032879", "l": "regulation of localization", "d": ["Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034607", "l": "turning behavior involved in mating", "d": ["The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010493", "l": "Lewis a epitope biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010090", "l": "trichome morphogenesis", "d": ["The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098530", "l": "positive regulation of strand invasion", "d": ["Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905231", "l": "cellular response to borneol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0009956", "l": "radial pattern formation", "d": ["The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0034643", "l": "establishment of mitochondrion localization, microtubule-mediated", "d": ["The directed movement of the mitochondrion to a specific location, by a process involving microtubules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042339", "l": "keratan sulfate metabolic process", "d": ["The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033604", "l": "negative regulation of catecholamine secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043685", "l": "conversion of glutamyl-tRNA to glutaminyl-tRNA", "d": ["The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060734", "l": "regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0034310", "l": "primary alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1904180", "l": "negative regulation of membrane depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "36.211735080897974", "identifiers": [{"i": "GO:0021915", "l": "neural tube development", "d": ["The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018870", "l": "anaerobic 2-aminobenzoate metabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904157", "l": "DN4 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. 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The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048325", "l": "negative regulation of axial mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044375", "l": "regulation of peroxisome size", "d": ["Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000101", "l": "regulation of mammary stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mammary stem cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072272", "l": "proximal/distal pattern formation involved in metanephric nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035027", "l": "leading edge cell fate commitment", "d": ["The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006746", "l": "FADH2 metabolic process", "d": ["The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061956", "l": "penetration of cumulus oophorus", "d": ["The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.253827701590666", "identifiers": [{"i": "GO:1903825", "l": "organic acid transmembrane transport", "d": ["The process in which an organic acid is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0034287", "l": "detection of monosaccharide stimulus", "d": ["The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090064", "l": "activation of microtubule nucleation", "d": ["Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900266", "l": "negative regulation of substance P receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0031055", "l": "chromatin remodeling at centromere", "d": ["Dynamic structural changes in centromeric DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1990758", "l": "mitotic sister chromatid biorientation", "d": ["The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051882", "l": "mitochondrial depolarization", "d": ["The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060268", "l": "negative regulation of respiratory burst", "d": ["Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0043276", "l": "anoikis", "d": ["Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902943", "l": "positive regulation of voltage-gated chloride channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0044363", "l": "modulation of potassium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021820", "l": "extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration", "d": ["The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035621", "l": "ER to Golgi ceramide transport", "d": ["The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. 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During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0044082", "l": "symbiont-mediated perturbation of host small GTPase-mediated signal transduction", "d": ["A process in which a symbiont alters or subverts a small GTPase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0072039", "l": "regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.46281596354936", "identifiers": [{"i": "GO:0051253", "l": "negative regulation of RNA metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.773102578641854", "identifiers": [{"i": "GO:0031667", "l": "response to nutrient levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905191", "l": "positive regulation of metaphase/anaphase transition of meiosis II", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0033673", "l": "negative regulation of kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.023409404909437", "identifiers": [{"i": "GO:0072001", "l": "renal system development", "d": ["The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. 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In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.741169254015119", "identifiers": [{"i": "GO:1902679", "l": "negative regulation of RNA biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.262738290078808", "identifiers": [{"i": "GO:0006351", "l": "DNA-templated transcription", "d": ["The synthesis of an RNA transcript from a DNA template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002655", "l": "regulation of tolerance induction to nonself antigen", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051042", "l": "negative regulation of calcium-independent cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042270", "l": "protection from natural killer cell mediated cytotoxicity", "d": ["The process of protecting a cell from natural killer cell mediated cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035475", "l": "angioblast cell migration involved in selective angioblast sprouting", "d": ["The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010652", "l": "positive regulation of cell communication by chemical coupling", "d": ["Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0034340", "l": "response to type I interferon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0035307", "l": "positive regulation of protein dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903598", "l": "positive regulation of gap junction assembly", "d": ["Any process that activates or increases the frequency, rate or extent of gap junction assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010099", "l": "regulation of photomorphogenesis", "d": ["Any process that modulates the rate or extent of photomorphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061414", "l": "positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source", "d": ["A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019556", "l": "histidine catabolic process to glutamate and formamide", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051613", "l": "positive regulation of serotonin uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0002070", "l": "epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904259", "l": "regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0072319", "l": "vesicle uncoating", "d": ["A protein depolymerization process that results in the disassembly of vesicle coat proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097214", "l": "positive regulation of lysosomal membrane permeability", "d": ["Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003226", "l": "right ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0032094", "l": "response to food", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009221", "l": "pyrimidine deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0015942", "l": "formate metabolic process", "d": ["The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052781", "l": "chitobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900736", "l": "regulation of phospholipase C-activating G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0006113", "l": "fermentation", "d": ["The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902237", "l": "positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140880", "l": "terrein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018032", "l": "protein amidation", "d": ["Addition of an amide group from a glycine to a protein amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010849", "l": "regulation of proton-transporting ATPase activity, rotational mechanism", "d": ["Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905845", "l": "positive regulation of cellular response to gamma radiation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0042040", "l": "metal incorporation into metallo-molybdopterin complex", "d": ["The incorporation of a metal into a metallo-molybdopterin complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042039", "l": "vanadium incorporation into metallo-sulfur cluster", "d": ["The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001810", "l": "regulation of type I hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0120127", "l": "response to zinc ion starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904258", "l": "nuclear dicing body assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000897", "l": "amylopectin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an amylopectin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900594", "l": "(+)-kotanin metabolic process", "d": ["The chemical reactions and pathways involving (+)-kotanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901739", "l": "regulation of myoblast fusion", "d": ["Any process that modulates the frequency, rate or extent of myoblast fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.249098858391747", "identifiers": [{"i": "GO:0048925", "l": "lateral line system development", "d": ["The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903090", "l": "pyridoxal transmembrane transport", "d": ["The process in which pyridoxal is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0140215", "l": "regulation of D-aspartate import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0035773", "l": "insulin secretion involved in cellular response to glucose stimulus", "d": ["The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001287", "l": "negative regulation of caveolin-mediated endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "38.146416810402293", "identifiers": [{"i": "GO:0046903", "l": "secretion", "d": ["The controlled release of a substance by a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2001006", "l": "regulation of cellulose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cellulose biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900680", "l": "positive regulation of ferricrocin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014718", "l": "positive regulation of satellite cell activation involved in skeletal muscle regeneration", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0099514", "l": "synaptic vesicle cytoskeletal transport", "d": ["The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.976908003308438", "identifiers": [{"i": "GO:0006096", "l": "glycolytic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904851", "l": "positive regulation of establishment of protein localization to telomere", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.221379778443747", "identifiers": [{"i": "GO:0008299", "l": "isoprenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048315", "l": "conidium formation", "d": ["The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0001542", "l": "ovulation from ovarian follicle", "d": ["The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903024", "l": "positive regulation of ascospore-type prospore membrane formation", "d": ["Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0050936", "l": "xanthophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061327", "l": "anterior Malpighian tubule development", "d": ["The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039700", "l": "fusion of viral membrane with host outer nuclear membrane", "d": ["Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044472", "l": "envenomation resulting in modulation of calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901525", "l": "negative regulation of mitophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043554", "l": "aerobic respiration, using arsenite as electron donor", "d": ["The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035540", "l": "positive regulation of SNARE complex disassembly", "d": ["Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032337", "l": "positive regulation of activin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.683527111924249", "identifiers": [{"i": "GO:0008645", "l": "hexose transmembrane transport", "d": ["The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.823778999192399", "identifiers": [{"i": "GO:0060249", "l": "anatomical structure homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044321", "l": "response to leptin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120045", "l": "stereocilium maintenance", "d": ["The organization process that preserves a stereocilium in a stable functional or structural state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070484", "l": "dehydro-D-arabinono-1,4-lactone metabolic process", "d": ["The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003190", "l": "atrioventricular valve formation", "d": ["The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003320", "l": "heart rudiment involution", "d": ["The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0044525", "l": "peptidyl-cystine sulfhydration", "d": ["The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0019520", "l": "aldonic acid metabolic process", "d": ["The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031920", "l": "pyridoxal transport", "d": ["The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042722", "l": "alpha-beta T cell activation by superantigen", "d": ["The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902163", "l": "negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1903513", "l": "endoplasmic reticulum to cytosol transport", "d": ["The directed movement of substances from endoplasmic reticulum to cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904983", "l": "glycine import into mitochondrion", "d": ["The process in which glycine is transported from the cytosol into the mitochondrial matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052704", "l": "ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide", "d": ["The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0043582", "l": "sporangium development", "d": ["The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. 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This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038002", "l": "endocrine signaling", "d": ["The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061080", "l": "right horn of sinus venosus development", "d": ["The progression of the right horn of the sinus venosus from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0021523", "l": "somatic motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. 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Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071280", "l": "cellular response to copper ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1905071", "l": "tight junction disassembly", "d": ["The disaggregation of an tight junction into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036509", "l": "trimming of terminal mannose on B branch", "d": ["The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090675", "l": "intermicrovillar adhesion", "d": ["The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046668", "l": "regulation of retinal cell programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0007435", "l": "salivary gland morphogenesis", "d": ["The process in which the anatomical structures of the salivary gland are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061358", "l": "negative regulation of Wnt protein secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006799", "l": "polyphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110081", "l": "negative regulation of placenta blood vessel development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.078697315966167", "identifiers": [{"i": "GO:0043583", "l": "ear development", "d": ["The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0048134", "l": "germ-line cyst formation", "d": ["Formation of a group of interconnected cells derived from a single gonial founder cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0061113", "l": "pancreas morphogenesis", "d": ["Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140291", "l": "peptidyl-glutamate ADP-deribosylation", "d": ["The removal of ADP-ribose from ADP-ribosylglutamate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905724", "l": "positive regulation of trypanothione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031043", "l": "O-glycan processing, core 7", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140727", "l": "siRNA-mediated pericentric heterochromatin formation", "d": ["The formation of pericentric heterochromatin by a process mediated by a small interfering RNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0055071", "l": "manganese ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045658", "l": "regulation of neutrophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071947", "l": "protein deubiquitination involved in ubiquitin-dependent protein catabolic process", "d": ["The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0021559", "l": "trigeminal nerve development", "d": ["The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0046247", "l": "terpene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046273", "l": "lignan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070145", "l": "mitochondrial asparaginyl-tRNA aminoacylation", "d": ["The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030237", "l": "female sex determination", "d": ["The specification of female sex of an individual organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010613", "l": "positive regulation of cardiac muscle hypertrophy", "d": ["Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0150116", "l": "regulation of cell-substrate junction organization", "d": ["Any process that modulates the frequency, rate or extent of cell-substrate junction organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072715", "l": "cellular response to selenite ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0035806", "l": "perturbation of blood coagulation in another organism", "d": ["The process in which an organism effects a change that affects blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033376", "l": "establishment of protein localization to T cell secretory granule", "d": ["The directed movement of a protein to a location within a secretory granule in a T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010961", "l": "intracellular magnesium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of magnesium ions within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0014889", "l": "muscle atrophy", "d": ["A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0062099", "l": "negative regulation of programmed necrotic cell death", "d": ["Any process that decreases the frequency, rate or extent of programmed necrotic cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901207", "l": "regulation of heart looping", "d": ["Any process that modulates the frequency, rate or extent of heart looping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.33144287441435", "identifiers": [{"i": "GO:0043488", "l": "regulation of mRNA stability", "d": ["Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035445", "l": "borate transmembrane transport", "d": ["The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001294", "l": "malonyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061258", "l": "mesonephric podocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.551667831314546", "identifiers": [{"i": "GO:0010498", "l": "proteasomal protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0070233", "l": "negative regulation of T cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045583", "l": "regulation of cytotoxic T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0047484", "l": "regulation of response to osmotic stress", "d": ["Any process that modulates the rate or extent of the response to osmotic stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046124", "l": "purine deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019917", "l": "peptidyl-D-alanine racemization via peptidyl-L-serine", "d": ["The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019518", "l": "L-threonine catabolic process to glycine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902182", "l": "shoot apical meristem development", "d": ["The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0098528", "l": "skeletal muscle fiber differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018912", "l": "1,4-dichlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0006701", "l": "progesterone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001807", "l": "regulation of type IV hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002086", "l": "diaphragm contraction", "d": ["A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:1900911", "l": "regulation of olefin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of olefin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1901608", "l": "regulation of vesicle transport along microtubule", "d": ["Any process that modulates the frequency, rate or extent of vesicle transport along microtubule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0009933", "l": "meristem structural organization", "d": ["Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0070602", "l": "regulation of centromeric sister chromatid cohesion", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:1902576", "l": "negative regulation of nuclear cell cycle DNA replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:1902806", "l": "regulation of cell cycle G1/S phase transition", "d": ["Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0001946", "l": "lymphangiogenesis", "d": ["Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046179", "l": "keto-D-gluconate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900245", "l": "positive regulation of MDA-5 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0051589", "l": "negative regulation of neurotransmitter transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904590", "l": "negative regulation of protein import", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein import."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.201143870267188", "identifiers": [{"i": "GO:0070663", "l": "regulation of leukocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of leukocyte proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000874", "l": "regulation of glyoxylate cycle", "d": ["Any process that modulates the frequency, rate or extent of glyoxylate cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072747", "l": "cellular response to chloramphenicol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048693", "l": "regulation of collateral sprouting of injured axon", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070945", "l": "neutrophil-mediated killing of gram-negative bacterium", "d": ["The directed killing of a gram-negative bacterium by a neutrophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019732", "l": "antifungal humoral response", "d": ["An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902760", "l": "Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090155", "l": "negative regulation of sphingolipid biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009078", "l": "pyruvate family amino acid metabolic process", "d": ["The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0071616", "l": "acyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070778", "l": "L-aspartate transmembrane transport", "d": ["The directed movement of L-aspartate across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0048643", "l": "positive regulation of skeletal muscle tissue development", "d": ["Any process that activates, maintains or increases the rate of skeletal muscle tissue development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0019249", "l": "lactate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905831", "l": "negative regulation of spindle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060373", "l": "regulation of ventricular cardiac muscle cell membrane depolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044027", "l": "negative regulation of gene expression via CpG island methylation", "d": ["An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. 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Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905237", "l": "response to cyclosporin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.773588770116547", "identifiers": [{"i": "GO:0002685", "l": "regulation of leukocyte migration", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0060079", "l": "excitatory postsynaptic potential", "d": ["A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. 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Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060008", "l": "Sertoli cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. 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Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.225555187126616", "identifiers": [{"i": "GO:0042060", "l": "wound healing", "d": ["The series of events that restore integrity to a damaged tissue, following an injury."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018288", "l": "iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046202", "l": "cyanide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. 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A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0099607", "l": "lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. 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Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060757", "l": "adult foraging behavior", "d": ["Behavior by which an adult locates food."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021757", "l": "caudate nucleus development", "d": ["The progression of the caudate nucleus over time from its initial formation until its mature state. 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This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009854", "l": "oxidative photosynthetic carbon pathway", "d": ["The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030300", "l": "regulation of intestinal cholesterol absorption", "d": ["Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0000948", "l": "amino acid catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. 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This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. 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The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0001983", "l": "baroreceptor response to increased systemic arterial blood pressure", "d": ["The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000866", "l": "positive regulation of estradiol secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estradiol secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071286", "l": "cellular response to magnesium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0060285", "l": "cilium-dependent cell motility", "d": ["Cell motility due to the motion of one or more eukaryotic cilia. 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Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0002792", "l": "negative regulation of peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070178", "l": "D-serine metabolic process", "d": ["The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006065", "l": "UDP-glucuronate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0002711", "l": "positive regulation of T cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903087", "l": "mitotic spindle pole body duplication", "d": ["Any spindle pole body duplication that is involved in the mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.098012012402094", "identifiers": [{"i": "GO:0060537", "l": "muscle tissue development", "d": ["The progression of muscle tissue over time, from its initial formation to its mature state. 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extent of pectin catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044471", "l": "envenomation resulting in pore formation in membrane of another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006489", "l": "dolichyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000061", "l": "regulation of ureter smooth muscle cell differentiation", "d": ["Any process 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to fibroblast growth factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010888", "l": "negative regulation of lipid storage", "d": ["Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:1901796", "l": "regulation of signal transduction by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036242", "l": "glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071463", "l": "cellular response to humidity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0061107", "l": "seminal vesicle development", "d": ["The progression of the seminal vesicle over time, from its formation to the mature structure. 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They develop from the coelomic epithelial cells of the gonadal ridge."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042848", "l": "sorbose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. 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Further modifications of the backbone are common."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060141", "l": "positive regulation of syncytium formation by virus", "d": ["The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905513", "l": "negative regulation of short-term synaptic potentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900324", "l": "regulation of maltotriulose transport", "d": ["Any process that modulates the frequency, rate or extent of maltotriulose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055005", "l": "ventricular cardiac myofibril assembly", "d": ["The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. 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In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000910", "l": "negative regulation of sterol import", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sterol import."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090429", "l": "detection of endogenous biotic stimulus", "d": ["The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901025", "l": "ripoptosome assembly involved in extrinsic apoptotic signaling pathway", "d": ["The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903853", "l": "regulation of stress response to copper ion", "d": ["Any process that modulates the frequency, rate or extent of stress response to copper ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061207", "l": "mesonephric juxtaglomerulus cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002332", "l": "transitional stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow become mature B cells in the spleen. 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In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900846", "l": "regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019657", "l": "glycolytic fermentation to propionate", "d": ["Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0093001", "l": "glycolysis from storage polysaccharide through glucose-1-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061043", "l": "regulation of vascular wound healing", "d": ["Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007516", "l": "hemocyte development", "d": ["The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. 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Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904736", "l": "negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0006509", "l": "membrane protein ectodomain proteolysis", "d": ["The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018302", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075273", "l": "positive regulation of zygosporangium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035720", "l": "intraciliary anterograde transport", "d": ["The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905552", "l": "positive regulation of protein localization to endoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0009648", "l": "photoperiodism", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. 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"t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000198", "l": "negative regulation of ribonucleoprotein complex localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904250", "l": "positive regulation of age-related resistance", "d": ["Any process that activates or increases the extent of age-related resistance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048473", "l": "D-methionine transport", "d": ["The directed movement of D-methionine into, out of, within, or between cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901903", "l": "tyrocidine catabolic process", "d": ["The chemical reactions and 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"100", "identifiers": [{"i": "GO:1903839", "l": "positive regulation of mRNA 3'-UTR binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140977", "l": "cellular detoxification of acetone", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of acetone. 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Includes processes that both stabilize and destabilize mitochondrial mRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035393", "l": "chemokine (C-X-C motif) ligand 9 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903543", "l": "positive regulation of exosomal secretion", "d": ["Any process that activates or increases the frequency, rate or extent of exosomal secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061286", "l": "mesonephric capsule morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric capsule are generated and organized. 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It provides some protection from trauma and damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.33144287441435", "identifiers": [{"i": "GO:0032642", "l": "regulation of chemokine production", "d": ["Any process that modulates the frequency, rate, or extent of chemokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902433", "l": "positive regulation of water channel activity involved in maintenance of lens transparency", "d": ["Any positive regulation of water channel activity that is involved in maintenance of lens transparency."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015819", "l": "lysine transport", "d": ["The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000974", "l": "negative regulation of pro-B cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002402", "l": "B cell tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070808", "l": "regulation of Hulle cell development", "d": ["Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. 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The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0035290", "l": "trunk segmentation", "d": ["Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0060581", "l": "cell fate commitment involved in pattern specification", "d": ["The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.836106170294514", "identifiers": [{"i": "GO:0019318", "l": "hexose metabolic process", "d": ["The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060874", "l": "posterior semicircular canal development", "d": ["The progession of the posterior semicircular canal from its initial formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048900", "l": "anterior lateral line neuromast primordium migration", "d": ["The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006881", "l": "extracellular sequestering of iron ion", "d": ["The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0042590", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034260", "l": "negative regulation of GTPase activity", "d": ["Any process that stops or reduces the rate of GTP hydrolysis by a GTPase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902277", "l": "negative regulation of pancreatic amylase secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140509", "l": "epithelium-like organization", "d": ["The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035747", "l": "natural killer cell chemotaxis", "d": ["The directed movement of a natural killer cell guided by a specific chemical concentration gradient. 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Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.449113659480474", "identifiers": [{"i": "GO:0000723", "l": "telomere maintenance", "d": ["Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031442", "l": "positive regulation of mRNA 3'-end processing", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901537", "l": "positive regulation of DNA demethylation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA demethylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900602", "l": "endocrocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of endocrocin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051165", "l": "2,5-dihydroxypyridine metabolic process", "d": ["The chemical reactions and pathways involving 2,5-dihydroxypyridine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905813", "l": "negative regulation of motor neuron axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075325", "l": "spore dispersal", "d": ["Any process in which an organism disseminates its spores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140421", "l": "endocytic heme import into cell", "d": ["The directed movement into cell of externally available heme by receptor-mediated endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006784", "l": "heme A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0010165", "l": "response to X-ray", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060992", "l": "response to fungicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000541", "l": "positive regulation of protein geranylgeranylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0002661", "l": "regulation of B cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of B cell tolerance induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1990776", "l": "response to angiotensin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015730", "l": "propanoate transmembrane transport", "d": ["The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046701", "l": "insecticide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902889", "l": "protein localization to spindle microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within a spindle microtubule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904095", "l": "negative regulation of endosperm development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031950", "l": "negative regulation of glucocorticoid catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0032509", "l": "endosome transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0110004", "l": "positive regulation of tRNA methylation", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA methylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904904", "l": "regulation of endothelial cell-matrix adhesion via fibronectin", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0015920", "l": "lipopolysaccharide transport", "d": ["The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033305", "l": "chlorophyll a biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000878", "l": "positive regulation of oligopeptide transport", "d": ["Any process that activates or increases the frequency, rate or extent of oligopeptide transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019455", "l": "L-cysteine catabolic process via cystine, using cystine reductase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010066", "l": "ground meristem histogenesis", "d": ["The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031652", "l": "positive regulation of heat generation", "d": ["Any process that activates or increases the rate or extent of heat generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019330", "l": "aldoxime metabolic process", "d": ["The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099014", "l": "neuronal dense core vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033638", "l": "modulation by symbiont of host heat acclimation", "d": ["Any process in which an organism modulates the host's tolerance to high temperatures, above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021531", "l": "spinal cord radial glial cell differentiation", "d": ["The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039574", "l": "symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity", "d": ["A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase involved in numerous cytokines and interferons signaling pathways and transmits the cytokine signal by phosphorylating receptor subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901431", "l": "regulation of response to cycloalkane", "d": ["Any process that modulates the frequency, rate or extent of response to cycloalkane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002632", "l": "negative regulation of granuloma formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0030046", "l": "parallel actin filament bundle assembly", "d": ["Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021623", "l": "oculomotor nerve formation", "d": ["The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046511", "l": "sphinganine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0046134", "l": "pyrimidine nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904516", "l": "myofibroblast cell apoptotic process", "d": ["Any apoptotic process in a myofibroblast cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0090075", "l": "relaxation of muscle", "d": ["A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030259", "l": "lipid glycosylation", "d": ["Covalent attachment of a glycosyl residue to a lipid molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071608", "l": "macrophage inflammatory protein-1 alpha production", "d": ["The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006127", "l": "glycerophosphate shuttle", "d": ["The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.156270827921489", "identifiers": [{"i": "GO:0034763", "l": "negative regulation of transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0180018", "l": "cytoplasmic polyadenylation-dependent RNA catabolic process", "d": ["The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901045", "l": "negative regulation of egg-laying behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oviposition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042070", "l": "maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification", "d": ["Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0030049", "l": "muscle filament sliding", "d": ["The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033343", "l": "positive regulation of collagen binding", "d": ["Any process that activates or increases the frequency, rate or extent of collagen binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0006754", "l": "ATP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905593", "l": "positive regulation of optical nerve axon regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0006099", "l": "tricarboxylic acid cycle", "d": ["A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900535", "l": "palmitic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of palmitic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034021", "l": "response to silicon dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0002837", "l": "regulation of immune response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of an immune response to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.314050959231352", "identifiers": [{"i": "GO:0034204", "l": "lipid translocation", "d": ["The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1904305", "l": "negative regulation of gastro-intestinal system smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062102", "l": "female germline stem cell symmetric division", "d": ["Division of a female germline stem cell to produce two germline stem cells of the same type as the parent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904146", "l": "positive regulation of meiotic cell cycle process involved in oocyte maturation", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071233", "l": "cellular response to leucine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120221", "l": "maintenance of ciliary planar beating movement pattern", "d": ["Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097049", "l": "motor neuron apoptotic process", "d": ["Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032706", "l": "negative regulation of interleukin-22 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034054", "l": "symbiont-mediated suppression of host defense-related programmed cell death", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003223", "l": "ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.605953599968913", "identifiers": [{"i": "GO:0075136", "l": "response to host", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032125", "l": "micronucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902726", "l": "positive regulation of skeletal muscle satellite cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of satellite cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904707", "l": "positive regulation of vascular associated smooth muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060955", "l": "neural crest-derived cardiac glial cell fate commitment", "d": ["The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905219", "l": "regulation of platelet formation", "d": ["Any process that modulates the frequency, rate or extent of platelet formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905244", "l": "regulation of modification of synaptic structure", "d": ["Any process that modulates the frequency, rate or extent of modification of synaptic structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000709", "l": "regulation of maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:2000628", "l": "regulation of miRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of miRNA metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0048909", "l": "anterior lateral line nerve development", "d": ["The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900099", "l": "negative regulation of plasma cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.026622328051275", "identifiers": [{"i": "GO:0060004", "l": "reflex", "d": ["An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0070631", "l": "spindle pole body localization", "d": ["Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060659", "l": "nipple sheath formation", "d": ["The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046347", "l": "mannosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061094", "l": "regulation of turning behavior involved in mating", "d": ["Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002459", "l": "adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains", "d": ["An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904615", "l": "cellular response to biphenyl", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010246", "l": "rhamnogalacturonan I biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.474770398704251", "identifiers": [{"i": "GO:0032102", "l": "negative regulation of response to external stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0099137", "l": "altruistic, chimeric, non-reproductive fruiting body development", "d": ["Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903905", "l": "positive regulation of establishment of T cell polarity", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0030858", "l": "positive regulation of epithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090228", "l": "positive regulation of red or far-red light signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031153", "l": "slug development involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0018283", "l": "iron incorporation into metallo-sulfur cluster", "d": ["The incorporation of iron into a metallo-sulfur cluster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0014904", "l": "myotube cell development", "d": ["The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900608", "l": "tensidol B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tensidol B."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0002441", "l": "histamine secretion involved in inflammatory response", "d": ["The regulated release of histamine by a cell as part of an inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021694", "l": "cerebellar Purkinje cell layer formation", "d": ["The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0075015", "l": "formation of infection structure", "d": ["The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140542", "l": "regulation of piRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of a piRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009184", "l": "purine deoxyribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006673", "l": "inositol phosphoceramide metabolic process", "d": ["The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000702", "l": "regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140641", "l": "mitotic spindle formation (spindle phase two)", "d": ["The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.14133299147904", "identifiers": [{"i": "GO:0080134", "l": "regulation of response to stress", "d": ["Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0062109", "l": "regulation of DNA recombinase disassembly", "d": ["Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006530", "l": "asparagine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051083", "l": "'de novo' cotranslational protein folding", "d": ["The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0140074", "l": "cardiac endothelial to mesenchymal transition", "d": ["A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902228", "l": "positive regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904491", "l": "protein localization to ciliary transition zone", "d": ["A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003366", "l": "cell-matrix adhesion involved in ameboidal cell migration", "d": ["The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0021934", "l": "hindbrain tangential cell migration", "d": ["The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071334", "l": "cellular response to rhamnose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903304", "l": "positive regulation of pyruvate kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003259", "l": "cardioblast anterior-lateral migration", "d": ["The orderly movement of a cardioblast toward the head and laterally to form the heart field. 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Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120072", "l": "positive regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900649", "l": "regulation of dehydroaustinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901925", "l": "negative regulation of protein import into nucleus during spindle assembly checkpoint", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071344", "l": "diphosphate metabolic process", "d": ["The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902448", "l": "positive regulation of shade avoidance", "d": ["Any process that activates or increases the frequency, rate or extent of shade avoidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900721", "l": "positive regulation of uterine smooth muscle relaxation", "d": ["Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030327", "l": "prenylated protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prenylated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0051546", "l": "keratinocyte migration", "d": ["The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014864", "l": "detection of muscle activity", "d": ["The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902426", "l": "deactivation of mitotic spindle assembly checkpoint", "d": ["A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0045839", "l": "negative regulation of mitotic nuclear division", "d": ["Any process that stops, prevents or reduces the rate or extent of mitosis. 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pseudouridine in an snRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901752", "l": "leukotriene A4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene A4."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0006817", "l": "phosphate ion transport", "d": ["The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0061900", "l": "glial cell activation", "d": ["A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.756683046408256", "identifiers": [{"i": 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"GO:0006595", "l": "polyamine metabolic process", "d": ["The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904507", "l": "positive regulation of telomere maintenance in response to DNA damage", "d": ["Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904504", "l": "positive regulation of lipophagy", "d": ["Any process that activates or increases the frequency, rate or extent of lipophagy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901118", "l": "cephamycin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cephamycin C."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901955", "l": "negative regulation of retrograde dense core granule transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1990709", "l": "presynaptic active zone organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046322", "l": "negative regulation of fatty acid oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": 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Sometimes further septa form in each cell prior to disarticulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905148", "l": "negative regulation of smooth muscle hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902784", "l": "response to undecane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070246", "l": "natural killer cell apoptotic process", "d": ["Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900159", "l": "positive regulation of bone mineralization involved in bone maturation", "d": ["Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032985", "l": "protein-carbohydrate complex disassembly", "d": ["The disaggregation of a protein-carbohydrate complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0039695", "l": "DNA-templated viral transcription", "d": ["A transcription process that uses a viral DNA as a template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900139", "l": "negative regulation of arachidonic acid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032475", "l": "otolith formation", "d": ["The process that gives rise to an otolith. 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The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0051644", "l": "plastid localization", "d": ["Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0034088", "l": "maintenance of mitotic sister chromatid cohesion", "d": ["The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045609", "l": "positive regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002581", "l": "negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052787", "l": "alpha-linked polysaccharide catabolism to maltopentaose", "d": ["The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044500", "l": "envenomation resulting in negative regulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019046", "l": "release from viral latency", "d": ["The process by which a virus begins to replicate following a latency replication decision (switch)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.504650478785891", "identifiers": [{"i": "GO:0031365", "l": "N-terminal protein amino acid modification", "d": ["The alteration of the N-terminal amino acid residue in a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061386", "l": "closure of optic fissure", "d": ["The closure of the temporary ventral gap in the optic cup that contributes to its shaping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0035789", "l": "metanephric mesenchymal cell migration", "d": ["The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021929", "l": "stellate cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to stellate cells. 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This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. 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Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. 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Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900514", "l": "positive regulation of starch utilization system complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075524", "l": "ribosomal skipping", "d": ["A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0002715", "l": "regulation of natural killer cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0033058", "l": "directional locomotion", "d": ["Self-propelled movement of a cell or organism from one location to another along an axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0015693", "l": "magnesium ion transport", "d": ["The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032474", "l": "otolith morphogenesis", "d": ["The process in which the anatomical structures of an otolith are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.86759105459673", "identifiers": [{"i": "GO:0036072", "l": "direct ossification", "d": ["The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0052709", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903280", "l": "negative regulation of calcium:sodium antiporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0006578", "l": "amino-acid betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019746", "l": "hopanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039711", "l": "cytoplasmic helical capsid assembly", "d": ["The assembly of a helical viral capsid in the cytoplasm. 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May also include amplification of the siRNA by RNA-directed RNA polymerase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032833", "l": "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032540", "l": "positive regulation of host-seeking behavior", "d": ["Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901023", "l": "4-hydroxyphenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098005", "l": "viral head-tail joining", "d": ["Process by which virus heads and tails are attached to each other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000076", "l": "positive regulation of cytokinesis, site selection", "d": ["Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0014041", "l": "regulation of neuron maturation", "d": ["Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. 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A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0002290", "l": "gamma-delta T cell activation involved in immune response", "d": ["The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051583", "l": "dopamine uptake involved in synaptic transmission", "d": ["The directed movement of dopamine into a presynaptic neuron or glial cell. 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Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900821", "l": "orlandin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of orlandin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060222", "l": "regulation of retinal cone cell fate commitment", "d": ["Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. 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Mechanisms of negative selection include anergy and deletion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0021533", "l": "cell differentiation in hindbrain", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.232224033214663", "identifiers": [{"i": "GO:0019230", "l": "proprioception", "d": ["The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0001756", "l": "somitogenesis", "d": ["The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031550", "l": "positive regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0030103", "l": "vasopressin secretion", "d": ["The regulated release of vasopressin from secretory granules into the blood."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048301", "l": "positive regulation of isotype switching to IgD isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901321", "l": "positive regulation of heart induction", "d": ["Any process that activates or increases the frequency, rate or extent of heart induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019335", "l": "3-methylquinoline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090449", "l": "phloem 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chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032643", "l": "regulation of connective tissue growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of connective tissue growth factor production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000139", "l": "regulation of octopamine signaling pathway involved in response to food", "d": ["Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0006744", "l": "ubiquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903772", "l": "regulation of viral budding via host ESCRT complex", "d": ["Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0002835", "l": "negative regulation of response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900126", "l": "negative regulation of hyaluronan biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": 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The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043950", "l": "positive regulation of cAMP-mediated signaling", "d": ["Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070796", "l": "regulation of cleistothecium development", "d": ["Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046497", "l": "nicotinate nucleotide metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051516", "l": "regulation of bipolar cell growth", "d": ["Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036110", "l": "cellular response to inositol starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044515", "l": "envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0031453", "l": "positive regulation of heterochromatin formation", "d": ["Any process that activates or increases the frequency, rate or extent of heterochromatin formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000374", "l": "Group III intron splicing", "d": ["The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0099136", "l": "chimeric non-reproductive fruiting body development", "d": ["Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902697", "l": "valine catabolic process to isobutanol", "d": ["The chemical reactions and pathways resulting in the breakdown of valine to isobutanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904028", "l": "positive regulation of collagen fibril organization", "d": ["Any process that activates or increases the frequency, rate or extent of collagen fibril organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017183", "l": "protein histidyl modification to diphthamide", "d": ["The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.45786467499596", "identifiers": [{"i": "GO:0040034", "l": "regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035506", "l": "negative regulation of myosin light chain kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0071830", "l": "triglyceride-rich lipoprotein particle clearance", "d": ["The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060604", "l": "mammary gland duct cavitation", "d": ["Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000753", "l": "positive regulation of glucosylceramide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071962", "l": "mitotic sister chromatid cohesion, centromeric", "d": ["The cell cycle process in which centromeres of sister chromatids are joined during mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033090", "l": "positive regulation of extrathymic T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904744", "l": "positive regulation of telomeric DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902998", "l": "positive regulation of neurofibrillary tangle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904134", "l": "negative regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0019070", "l": "viral genome maturation", "d": ["The processes involved in creating a mature, stable viral genome. 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Includes the addition of proteins to the newly synthesized genome, and DNA repair processes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0120322", "l": "lipid modification by small protein conjugation", "d": ["A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0120194", "l": "regulation of anther dehiscence", "d": ["Any process involved in the dehiscence of an anther to release the pollen grains contained within it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048837", "l": "sorocarp sorus development", "d": ["The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0038011", "l": "negative regulation of signal transduction by receptor internalization", "d": ["Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035503", "l": "ureter part of ureteric bud development", "d": ["The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017192", "l": "N-terminal peptidyl-glutamine acetylation", "d": ["The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000093", "l": "regulation of mesonephric nephron tubule epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044361", "l": "negative regulation of voltage-gated potassium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900447", "l": "regulation of cell morphogenesis involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. 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In non-mammalian species, absorption may occur in related structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901494", "l": "regulation of cysteine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cysteine metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021589", "l": "cerebellum structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021836", "l": "chemorepulsion involved in postnatal olfactory bulb interneuron migration", "d": ["The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042751", "l": "estivation", "d": ["Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010758", "l": "regulation of macrophage chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.156270827921489", "identifiers": [{"i": "GO:0062207", "l": "regulation of pattern recognition receptor signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0022028", "l": "tangential migration from the subventricular zone to the olfactory bulb", "d": ["The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002617", "l": "negative regulation of macrophage antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060540", "l": "diaphragm morphogenesis", "d": ["The process in which the anatomical structures of the diaphragm are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009714", "l": "chalcone metabolic process", "d": ["The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001692", "l": "histamine metabolic process", "d": ["The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061648", "l": "tooth replacement", "d": ["The process whose specific outcome is the replacement of an existing tooth with another tooth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019918", "l": "peptidyl-arginine methylation, to symmetrical-dimethyl arginine", "d": ["The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061183", "l": "regulation of dermatome development", "d": ["Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003111", "l": "positive regulation of heart rate by circulating epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034172", "l": "negative regulation of toll-like receptor 11 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070501", "l": "poly-gamma-glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.340966656807453", "identifiers": [{"i": "GO:0045089", "l": "positive regulation of innate immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0048266", "l": "behavioral response to pain", "d": ["Any process that results in a change in the behavior of an organism as a result of a pain stimulus. 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Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075502", "l": "endosome membrane permeabilization involved in viral entry into host cell", "d": ["Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904140", "l": "negative regulation of microglial cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0015751", "l": "arabinose transmembrane transport", "d": ["The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061855", "l": "negative regulation of neuroblast migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048377", "l": "lateral mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032875", "l": "regulation of DNA endoreduplication", "d": ["Any process that modulates the frequency, rate or extent of DNA endoreduplication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0060713", "l": "labyrinthine layer morphogenesis", "d": ["The process in which the labyrinthine layer of the placenta is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000971", "l": "negative regulation of detection of glucose", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075004", "l": "adhesion of symbiont spore to host", "d": ["The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090327", "l": "negative regulation of locomotion involved in locomotory behavior", "d": ["Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031150", "l": "sorocarp stalk development", "d": ["The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. 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The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0043173", "l": "nucleotide salvage", "d": ["Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0097240", "l": "chromosome attachment to the nuclear envelope", "d": ["The process in which chromatin is anchored to the nuclear envelope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0000749", "l": "response to pheromone triggering conjugation with cellular fusion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010456", "l": "cell proliferation in dorsal spinal cord", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0140766", "l": "siRNA-mediated post-transcriptional gene silencing", "d": ["A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into a RNA-induced silencing complex (RISC), siRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the mRNA or mRNA translational repression. siRNAs are present in lower animals and plants, but not found in mammals; whereas miRNAs are present in all the animals and in plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0106023", "l": "regulation of pupariation", "d": ["Any process that modulates the onset of pupariation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070366", "l": "regulation of hepatocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106273", "l": "cytosol to ERGIC protein transport", "d": ["The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1905065", "l": "positive regulation of vascular associated smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033532", "l": "stachyose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010513", "l": "positive regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0000092", "l": "mitotic anaphase B", "d": ["The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014891", "l": "striated muscle atrophy", "d": ["A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990456", "l": "mitochondrion-endoplasmic reticulum membrane tethering", "d": ["The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070889", "l": "platelet alpha granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0032071", "l": "regulation of endodeoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009178", "l": "pyrimidine deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010748", "l": "negative regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. 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The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035864", "l": "response to potassium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046641", "l": "positive regulation of alpha-beta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0015843", "l": "methylammonium transport", "d": ["The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009677", "l": "double fertilization forming two zygotes", "d": ["Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. 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It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0001649", "l": "osteoblast differentiation", "d": ["The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0014876", "l": "response to injury involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. 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Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0051450", "l": "myoblast proliferation", "d": ["The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006431", "l": "methionyl-tRNA aminoacylation", "d": ["The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044696", "l": "killing by virus of host cell by post-segregational killing", "d": ["The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900344", "l": "positive regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034143", "l": "regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036060", "l": "slit diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048702", "l": "embryonic neurocranium morphogenesis", "d": ["The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. 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The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0043304", "l": "regulation of mast cell degranulation", "d": ["Any process that modulates the frequency, rate, or extent of mast cell degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043707", "l": "cell adhesion involved in single-species biofilm formation in or on host organism", "d": ["The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120073", "l": "negative regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032472", "l": "Golgi calcium ion transport", "d": ["The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900243", "l": "negative regulation of synaptic vesicle endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900231", "l": "regulation of single-species biofilm formation on inanimate substrate", "d": ["Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036184", "l": "asperthecin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0048440", "l": "carpel development", "d": ["The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. 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The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009079", "l": "pyruvate family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900559", "l": "austinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of austinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097103", "l": "endothelial stalk cell fate specification", "d": ["The process involved in the specification of identity of an endothelial stalk cell. 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An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0003057", "l": "regulation of the force of heart contraction by chemical signal", "d": ["The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901354", "l": "response to L-canavanine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901534", "l": "positive regulation of hematopoietic progenitor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042820", "l": "vitamin B6 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0018948", "l": "xylene metabolic process", "d": ["The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140450", "l": "protein targeting to Golgi apparatus", "d": ["The process of targeting specific proteins to the Golgi apparatus. 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The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002206", "l": "gene conversion of immunoglobulin genes", "d": ["The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010407", "l": "non-classical arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:1903035", "l": "negative regulation of response to wounding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002614", "l": "negative regulation of monocyte antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110052", "l": "toxic metabolite repair", "d": ["A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019639", "l": "6-hydroxycineole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902446", "l": "regulation of shade avoidance", "d": ["Any process that modulates the frequency, rate or extent of shade avoidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060791", "l": "sebaceous gland placode formation", "d": ["The developmental process in which a sebaceous gland placode forms. 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Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. 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Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:1901336", "l": "lactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042186", "l": "o-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014748", "l": "negative regulation of tonic skeletal muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0016264", "l": "gap junction assembly", "d": ["Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. 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Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "35.112210671735347", "identifiers": [{"i": "GO:0050896", "l": "response to stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905917", "l": "positive regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010305", "l": "leaf vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the leaf of vascular plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0010712", "l": "regulation of collagen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141104", "l": "symbiont-mediated activation of host G protein-coupled receptor signal transduction", "d": ["A process in which a symbiont initiates, promotes, or enhances a G protein-coupled receptor signal transduction pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051220", "l": "cytoplasmic sequestering of protein", "d": ["The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0043452", "l": "cellular alkyne metabolic process", "d": ["The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904536", "l": "regulation of mitotic 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0001878", "l": "response to yeast", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007545", "l": "processes downstream of sex determination signal", "d": ["The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035783", "l": "CD4-positive, alpha-beta T cell costimulation", "d": ["The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that 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This plays an important role in progression through meiosis and precedes synapsis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003088", "l": "positive regulation of the force of heart contraction by circulating epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003343", "l": "septum transversum development", "d": ["The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902063", "l": "betaine aldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of betaine aldehyde."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048883", "l": "neuromast primordium migration", "d": ["The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0042067", "l": "establishment of ommatidial planar polarity", "d": ["The specification of polarized ommatidia. Ommatidia occur in two chiral forms. 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Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. 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A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099531", "l": "presynaptic process involved in chemical synaptic transmission", "d": ["The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035854", "l": "eosinophil fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. 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{"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000851", "l": "positive regulation of glucocorticoid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000292", "l": "RNA fragment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0086013", "l": "membrane repolarization during cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of 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Generally fish have one or two dorsal fins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033586", "l": "L-phenylalanine biosynthetic process from chorismate via L-arogenate", "d": ["The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901895", "l": "negative regulation of ATPase-coupled calcium transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901438", "l": "negative regulation of toluene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021731", "l": "trigeminal motor nucleus development", "d": ["The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072392", "l": "phenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033524", "l": "sinapate ester metabolic process", "d": ["The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.551441031963407", "identifiers": [{"i": "GO:1901661", "l": "quinone metabolic process", "d": ["The chemical reactions and pathways involving quinone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044503", "l": "modulation of G protein-coupled receptor activity in another organism", "d": ["The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006702", "l": "androgen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051391", "l": "tRNA acetylation", "d": ["The modification of tRNA structure by addition of an acetyl group to tRNA. 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The critical day length varies between species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0006498", "l": "N-terminal protein lipidation", "d": ["The covalent attachment of a lipid group to the amino terminus of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003055", "l": "circadian regulation of heart rate by the suprachiasmatic nucleus", "d": ["The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051221", "l": "tungsten incorporation into metallo-sulfur cluster", "d": ["The incorporation of tungsten into a metallo-sulfur cluster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140745", "l": "siRNA transcription", "d": ["The transcription of a small interfering RNA from an RNA template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0055008", "l": "cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of cardiac muscle tissue are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061295", "l": "regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018185", "l": "poly-N-methyl-propylamination", "d": ["The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002210", "l": "behavioral response to wounding", "d": ["A behavioral response resulting from wounding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.664903707618308", "identifiers": [{"i": "GO:0010565", "l": "regulation of cellular ketone metabolic process", "d": ["Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. 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Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0030730", "l": "sequestering of triglyceride", "d": ["The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903075", "l": "pyridoxine import across plasma membrane", "d": ["The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030576", "l": "Cajal body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006792", "l": "regulation of sulfur utilization", "d": ["Any process that modulates the frequency, rate or extent of sulfur utilization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000614", "l": "positive regulation of thyroid-stimulating hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062056", "l": "compound eye pigment cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000571", "l": "regulation of interleukin-4-dependent isotype switching to IgE isotypes", "d": ["Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034194", "l": "D-galactonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051291", "l": "protein heterooligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. 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Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045726", "l": "positive regulation of integrin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900889", "l": "positive regulation of pentadecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090256", "l": "regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis", "d": ["Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903461", "l": "Okazaki fragment processing involved in mitotic DNA replication", "d": ["Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072696", "l": "positive regulation of DNA recombination at telomere", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0071869", "l": "response to catecholamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. 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The bud elongates and branches to give rise to the ureter and kidney collecting tubules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905949", "l": "negative regulation of calcium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000992", "l": "negative regulation of galactomannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060954", "l": "neural crest-derived cardiac glial cell development", "d": ["The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.014330232248525", "identifiers": [{"i": "GO:0050918", "l": "positive chemotaxis", "d": ["The directed movement of a motile cell or organism towards a higher concentration of a chemical."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075189", "l": "positive regulation of hyphopodium formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. 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Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035149", "l": "lumen formation, open tracheal system", "d": ["Creation of the central hole of a tube in an open tracheal system through which gases flow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.876091073600094", "identifiers": [{"i": "GO:0070482", "l": "response to oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0016322", "l": "neuron remodeling", "d": ["The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900833", "l": "D-leucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-leucine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902608", "l": "positive regulation of large conductance calcium-activated potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0030174", "l": "regulation of DNA-templated DNA replication initiation", "d": ["Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. 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An aorta is an artery that carries blood from the heart to other parts of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000011", "l": "regulation of adaxial/abaxial pattern formation", "d": ["Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070741", "l": "response to interleukin-6", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000158", "l": "positive regulation of ubiquitin-specific protease activity", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072261", "l": "metanephric extraglomerular mesangial cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. 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Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006359", "l": "regulation of transcription by RNA polymerase III", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0120256", "l": "olefinic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070550", "l": "rDNA chromatin condensation", "d": ["The process in which the chromatin structure of the rDNA repeats is compacted. 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An example can be found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048504", "l": "regulation of timing of animal organ formation", "d": ["Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0010770", "l": "positive regulation of cell morphogenesis", "d": ["Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. 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This process pertains to the initial formation of a structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0099517", "l": "synaptic vesicle transport along microtubule", "d": ["The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010877", "l": "lipid transport involved in lipid storage", "d": ["The directed movement of lipids into cells that is part of their accumulation and maintenance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:1904498", "l": "protein localization to mitotic actomyosin contractile ring", "d": ["Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075185", "l": "positive regulation of infection cushion formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902154", "l": "positive regulation of response to DNA damage checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.726079367374183", "identifiers": [{"i": "GO:0071621", "l": "granulocyte chemotaxis", "d": ["The movement of a granulocyte in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045468", "l": "regulation of R8 cell spacing in compound eye", "d": ["Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002847", "l": "negative regulation of T cell tolerance induction to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046644", "l": "negative regulation of gamma-delta T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034552", "l": "respiratory chain complex II assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0032995", "l": "regulation of fungal-type cell wall biogenesis", "d": ["Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099546", "l": "protein catabolic process, modulating synaptic transmission", "d": ["Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010597", "l": "green leaf volatile biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0098702", "l": "adenine import across plasma membrane", "d": ["The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.622818063453323", "identifiers": [{"i": "GO:0048584", "l": "positive regulation of response to stimulus", "d": ["Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900615", "l": "emericellamide A metabolic process", "d": ["The chemical reactions and pathways involving emericellamide A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000489", "l": "maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035480", "l": "regulation of Notch signaling pathway involved in heart induction", "d": ["Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021624", "l": "oculomotor nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001130", "l": "methane biosynthetic process from trimethylamine", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070072", "l": "vacuolar proton-transporting V-type ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048549", "l": "positive regulation of pinocytosis", "d": ["Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046517", "l": "octamethylcyclotetrasiloxane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043201", "l": "response to leucine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0033034", "l": "positive regulation of myeloid cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904119", "l": "negative regulation of otic vesicle morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901208", "l": "negative regulation of heart looping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heart looping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015834", "l": "peptidoglycan-associated peptide transport", "d": ["The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034115", "l": "negative regulation of heterotypic cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035711", "l": "T-helper 1 cell activation", "d": ["The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0045738", "l": "negative regulation of DNA repair", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021719", "l": "superior olivary nucleus morphogenesis", "d": ["The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990256", "l": "signal clustering", "d": ["Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097267", "l": "omega-hydroxylase P450 pathway", "d": ["The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019617", "l": "protocatechuate catabolic process, meta-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072304", "l": "regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of 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into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0071774", "l": "response to fibroblast growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902427", "l": "regulation of water channel activity", "d": ["Any process that modulates the frequency, rate or extent of water channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072257", "l": "metanephric nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045584", "l": "negative regulation of cytotoxic T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106397", "l": "positive regulation of R7 cell fate commitment", "d": ["Any process that activates or increases the frequency, rate or extent of R7 cell fate commitment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0003197", "l": "endocardial cushion development", "d": ["The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0098671", "l": "adhesion receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902133", "l": "(+)-secoisolariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (+)-secoisolariciresinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019749", "l": "cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte", "d": ["The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0019563", "l": "glycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.088320895280148", "identifiers": [{"i": "GO:0002577", "l": "regulation of antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0060438", "l": "trachea development", "d": ["The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072488", "l": "ammonium transmembrane transport", "d": ["The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1901403", "l": "positive regulation of tetrapyrrole metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0072098", "l": "anterior/posterior pattern specification involved in kidney development", "d": ["The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905623", "l": "positive regulation of leaf development", "d": ["Any process that activates or increases the frequency, rate or extent of leaf development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902770", "l": "negative regulation of choline O-acetyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060334", "l": "regulation of type II interferon-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.098012012402094", "identifiers": [{"i": "GO:0010721", "l": "negative regulation of cell development", "d": ["Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030207", "l": "chondroitin sulfate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043636", "l": "bisphenol A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990402", "l": "embryonic liver development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0046490", "l": "isopentenyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900792", "l": "shamixanthone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of shamixanthone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0072596", "l": "establishment of protein localization to chloroplast", "d": ["The directed movement of a protein to a specific location in a chloroplast."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000457", "l": "endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061131", "l": "pancreas field specification", "d": ["The process in which a specific region of the gut is delineated into the area in which the pancreas will develop."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905094", "l": "regulation of apolipoprotein A-I-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032691", "l": "negative regulation of interleukin-1 beta production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0052315", "l": "phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901892", "l": "negative regulation of cell septum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904675", "l": "regulation of somatic stem cell division", "d": ["Any process that modulates the frequency, rate or extent of somatic stem cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045345", "l": "positive regulation of MHC class I biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "36.158746340897451", "identifiers": [{"i": "GO:0009792", "l": "embryo development ending in birth or egg hatching", "d": ["The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0006269", "l": "DNA replication, synthesis of RNA primer", "d": ["The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001111", "l": "RNA polymerase II promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905903", "l": "negative regulation of mesoderm formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010747", "l": "positive regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085044", "l": "symbiont-mediated disruption of host cuticle", "d": ["The process in which an organism effects a change that impairs the structure or function of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090210", "l": "regulation of establishment of blood-brain barrier", "d": ["Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "46.047097353268782", "identifiers": [{"i": "GO:0044281", "l": "small molecule metabolic process", "d": ["The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042052", "l": "rhabdomere development", "d": ["The assembly and arrangement of a rhabdomere within a cell. 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The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018269", "l": "GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048463", "l": "carpel structural organization", "d": ["The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016330", "l": "second mitotic wave involved in compound eye morphogenesis", "d": ["A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010376", "l": "stomatal complex formation", "d": ["The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034119", "l": "negative regulation of erythrocyte aggregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061541", "l": "rhabdomere morphogenesis", "d": ["The process in which the anatomical structures of a rhabdomere are generated and organized. 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Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0031038", "l": "myosin II filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0019566", "l": "arabinose metabolic process", "d": ["The chemical reactions and pathways involving arabinose, arabino-pentose. 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Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048166", "l": "mature follicle stage", "d": ["The stage in oogenesis when the antrum is swollen with follicular fluid. 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"t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061633", "l": "transport-coupled glycolytic process through glucose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009665", "l": "plastid inheritance", "d": ["The partitioning of plastids between daughter cells at cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097096", "l": "facial suture morphogenesis", "d": ["The process in which any suture between facial bones is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0009453", 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A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003400", "l": "regulation of COPII vesicle coating", "d": ["Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035875", "l": "maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.960002279600147", "identifiers": [{"i": "GO:1901654", "l": "response to ketone", "d": ["A response that results in a state of tolerance to ketone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010989", "l": "negative regulation of low-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. 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Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000524", "l": "negative regulation of T cell costimulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045850", "l": "positive regulation of nurse cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007321", "l": "sperm displacement", "d": ["The physical displacement of sperm stored from previous mating encounters."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034036", "l": "purine ribonucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0031122", "l": "cytoplasmic microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000647", "l": "negative regulation of stem cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046500", "l": "S-adenosylmethionine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900045", "l": "negative regulation of protein K63-linked ubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0051495", "l": "positive regulation of cytoskeleton organization", "d": ["Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905858", "l": "regulation of heparan sulfate proteoglycan binding", "d": ["Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075288", "l": "negative regulation of sporangiospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006478", "l": "peptidyl-tyrosine sulfation", "d": ["The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0019889", "l": "pteridine metabolic process", "d": ["The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090205", "l": "positive regulation of cholesterol metabolic process", "d": ["Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000951", "l": "methionine catabolic process to 3-methylthiopropanol", "d": ["The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010845", "l": "positive regulation of reciprocal meiotic recombination", "d": ["Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007470", "l": "prothoracic disc morphogenesis", "d": ["The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0070342", "l": "brown fat cell proliferation", "d": ["The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0042365", "l": "water-soluble vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.504650478785891", "identifiers": [{"i": "GO:0001821", "l": "histamine secretion", "d": ["The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0141113", "l": "negative regulation of Wnt signaling pathway, planar cell polarity pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway, planar cell polarity pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905681", "l": "negative regulation of innate immunity memory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0030473", "l": "nuclear migration along microtubule", "d": ["The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018148", "l": "RNA-protein covalent cross-linking via peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010196", "l": "nonphotochemical quenching", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035782", "l": "mature natural killer cell chemotaxis", "d": ["The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021606", "l": "accessory nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.817691204291755", "identifiers": [{"i": "GO:0061535", "l": "glutamate secretion, neurotransmission", "d": ["The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051352", "l": "negative regulation of ligase activity", "d": ["Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072724", "l": "response to 4-nitroquinoline N-oxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009243", "l": "O antigen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071419", "l": "cellular response to amphetamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901447", "l": "positive regulation of response to propan-1-ol", "d": ["Any process that activates or increases the frequency, rate or extent of response to propan-1-ol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.462556264061433", "identifiers": [{"i": "GO:0003006", "l": "developmental process involved in reproduction", "d": ["A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034233", "l": "regulation of cell wall chitin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0018104", "l": "peptidoglycan-protein cross-linking", "d": ["The process of covalently linking peptidoglycan (murein) to proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.165923234534326", "identifiers": [{"i": "GO:0051046", "l": "regulation of secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018186", "l": "peroxidase-heme linkage", "d": ["The covalent linkage of heme to peroxidase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042374", "l": "phylloquinone metabolic process", "d": ["The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009386", "l": "translational attenuation", "d": ["Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071490", "l": "cellular response to far red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006610", "l": "ribosomal protein import into nucleus", "d": ["The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903354", "l": "regulation of distal tip cell migration", "d": ["Any process that modulates the frequency, rate or extent of distal tip cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001717", "l": "conversion of seryl-tRNAsec to selenocys-tRNAsec", "d": ["The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905693", "l": "regulation of phosphatidic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901599", "l": "(-)-pinoresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-pinoresinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046107", "l": "uracil biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902900", "l": "gut granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a gut granule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000917", "l": "positive regulation of glucuronoxylan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:2000407", "l": "regulation of T cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of T cell extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033563", "l": "dorsal/ventral axon guidance", "d": ["The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032349", "l": "positive regulation of aldosterone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1904338", "l": "regulation of dopaminergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.732058627946785", "identifiers": [{"i": "GO:0005975", "l": "carbohydrate metabolic process", "d": ["The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900299", "l": "positive regulation of hexasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of hexasaccharide transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000830", "l": "positive regulation of parathyroid hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009145", "l": "purine nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904345", "l": "negative regulation of gastric mucosal blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001171", "l": "positive regulation of ATP biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0019080", "l": "viral gene expression", "d": ["A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). 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Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001548", "l": "follicular fluid formation in ovarian follicle antrum", "d": ["The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046047", "l": "TTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009810", "l": "stilbene metabolic process", "d": ["The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002492", "l": "peptide antigen assembly with MHC class Ib protein complex", "d": ["The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. 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As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060399", "l": "positive regulation of growth hormone receptor signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. 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The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070614", "l": "tungstate ion transport", "d": ["The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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An amino acid is a carboxylic acids containing one or more amino groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0030432", "l": "peristalsis", "d": ["A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0015700", "l": "arsenite transport", "d": ["The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0008078", "l": "mesodermal cell migration", "d": ["The orderly movement of mesodermal cells from one site to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009780", "l": "photosynthetic NADP+ reduction", "d": ["An NADPH regeneration process that contributes to the light reactions of photosynthesis. 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NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.200460111606588", "identifiers": [{"i": "GO:0051093", "l": "negative regulation of developmental process", "d": ["Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0031397", "l": "negative regulation of protein ubiquitination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900584", "l": "o-orsellinic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of o-orsellinic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045668", "l": "negative regulation of osteoblast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904024", "l": "negative regulation of glucose catabolic process to lactate via pyruvate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010221", "l": "negative regulation of vernalization response", "d": ["Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905914", "l": "positive regulation of calcium ion export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:1903523", "l": "negative regulation of blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050677", "l": "positive regulation of urothelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of urothelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032802", "l": "low-density lipoprotein particle receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0100008", "l": "regulation of fever generation by prostaglandin biosynthetic process", "d": ["Any prostaglandin biosynthetic process process that regulates fever generation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043710", "l": "cell adhesion involved in multi-species biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000367", "l": "regulation of acrosomal vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010929", "l": "positive regulation of auxin mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. 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TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0061250", "l": "mesonephric glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. 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The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035685", "l": "helper T cell diapedesis", "d": ["The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903663", "l": "L-altrarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-altrarate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.161717068681156", "identifiers": [{"i": "GO:0043065", "l": "positive regulation of apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039690", "l": "positive stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). 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Coal tar produced at high temperature contains an average of 1.5% carbazole. 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Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.063228182036127", "identifiers": [{"i": "GO:0006090", "l": "pyruvate metabolic process", "d": ["The chemical reactions and pathways involving pyruvate, 2-oxopropanoate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0018293", "l": "protein-FAD linkage", "d": ["The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033349", "l": "apiose metabolic process", "d": ["The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose."], "t": []}], "taxa": []} 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902207", "l": "positive regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140967", "l": "manganese import into cell", "d": ["The directed movement of mangnanese ions from outside of a cell into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001296", "l": "N(omega)-methyl-L-arginine metabolic process", "d": ["The chemical reactions and pathways involving N(omega)-methyl-L-arginine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044828", "l": "negative regulation by host of viral genome replication", "d": ["A process in which a host 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901945", "l": "miltiradiene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of miltiradiene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0034109", "l": "homotypic cell-cell adhesion", "d": ["The attachment of a cell to a second cell of the identical type via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048621", "l": "post-embryonic digestive tract morphogenesis", "d": ["The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. 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The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1900121", "l": "negative regulation of receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002192", "l": "IRES-dependent translational initiation of linear mRNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070831", "l": "basement membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045805", "l": "positive regulation of eclosion", "d": ["Any process that activates or increases the frequency, rate or extent of eclosion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006408", "l": "snRNA export from nucleus", "d": ["The directed movement of snRNA from the nucleus to the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099559", "l": "maintenance of alignment of postsynaptic density and presynaptic active zone", "d": ["The process by which alignment between postsynaptic density and presynaptic active zone is maintained."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019473", "l": "L-lysine catabolic process to glutarate, by acetylation", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021773", "l": "striatal medium spiny neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.726079367374183", "identifiers": [{"i": "GO:0006874", "l": "intracellular calcium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000777", "l": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia", "d": ["Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0003235", "l": "sinus venosus development", "d": ["The progression of the sinus venosus over time, from its formation to the mature structure. 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Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. 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This process also regulates skeletal muscle adapatation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0034182", "l": "regulation of maintenance of mitotic sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0030716", "l": "oocyte fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000318", "l": "positive regulation of T-helper 17 type immune response", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0007007", "l": "inner mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0086043", "l": "bundle of His cell action potential", "d": ["An action potential that occurs in a bundle of His cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061147", "l": "endocardial endothelium development", "d": ["The progression of the endocardial endothelium over time, from its initial formation to the mature structure. 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Organophosphate esters are small organic molecules containing phosphate ester bonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046166", "l": "glyceraldehyde-3-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000047", "l": "regulation of cell-cell adhesion mediated by cadherin", "d": ["Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090018", "l": "posterior neural plate formation", "d": ["The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0051940", "l": "regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000990", "l": "positive regulation of hemicellulose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904703", "l": "negative regulation of protein localization to adherens junction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. 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The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051639", "l": "actin filament network formation", "d": ["The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0002028", "l": "regulation of sodium ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032097", "l": "positive regulation of response to food", "d": ["Any process that activates, maintains, or increases the rate of a response to a food stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903671", "l": "negative regulation of sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900742", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to pH", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0046813", "l": "receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019329", "l": "ammonia oxidation", "d": ["The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901178", "l": "spheroidene metabolic process", "d": ["The chemical reactions and pathways involving spheroidene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046799", "l": "recruitment of helicase-primase complex to DNA lesions", "d": ["The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060674", "l": "placenta blood vessel development", "d": ["The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002321", "l": "natural killer cell progenitor differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048742", "l": "regulation of skeletal muscle fiber development", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. 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"biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1902776", "l": "6-sulfoquinovose(1-) metabolic process", "d": ["The chemical reactions and pathways involving 6-sulfoquinovose(1-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097331", "l": "response to cytarabine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904420", "l": "positive regulation of telomeric loop formation", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric loop formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090156", "l": "intracellular sphingolipid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035921", "l": "desmosome disassembly", "d": ["The controlled breakdown of a desmosome. 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"identifiers": [{"i": "GO:1900011", "l": "negative regulation of corticotropin-releasing hormone receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006607", "l": "NLS-bearing protein import into nucleus", "d": ["The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0046113", "l": "nucleobase catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0090609", "l": "single-species submerged biofilm formation", "d": ["A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044499", "l": "envenomation resulting in positive regulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904076", "l": "regulation of estrogen biosynthetic 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The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0150201", "l": "positive regulation of transport across blood-brain barrier", "d": ["Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046619", "l": "lens placode formation involved in camera-type eye formation", "d": ["Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035021", "l": "negative regulation of Rac protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051835", "l": "positive regulation of synapse structural plasticity", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990486", "l": "anaerobic fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. 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Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032818", "l": "negative regulation of natural killer cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0009068", "l": "aspartate family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002800", "l": "regulation of antifungal peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antifungal peptide secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.678575823370835", "identifiers": [{"i": "GO:0045785", "l": "positive regulation of cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019681", "l": "acetyl-CoA assimilation pathway", "d": ["The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904515", "l": "positive regulation of TORC2 signaling", "d": ["Any process that activates or increases the frequency, rate or extent of TORC2 signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.58909006025462", "identifiers": [{"i": "GO:0010154", "l": "fruit development", "d": ["The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. 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Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060989", "l": "lipid tube assembly involved in organelle fusion", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046528", "l": "imaginal disc fusion", "d": ["The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904637", "l": "cellular response to ionomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090356", "l": "negative regulation of auxin metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001123", "l": "maltoheptaose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a maltoheptaose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901307", "l": "positive regulation of spermidine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901744", "l": "2-deoxystreptamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006424", "l": "glutamyl-tRNA aminoacylation", "d": ["The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018428", "l": "copper incorporation into copper-sulfur cluster", "d": ["The incorporation of copper into a copper-sulfur cluster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905194", "l": "positive regulation of chloroplast fission", "d": ["Any process that activates or increases the frequency, rate or extent of chloroplast fission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060818", "l": "inactivation of paternal X chromosome by genomic imprinting", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903432", "l": "regulation of TORC1 signaling", "d": ["Any process that modulates the frequency, rate or extent of TORC1 signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015737", "l": "galacturonate transmembrane transport", "d": ["The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1990180", "l": "mitochondrial tRNA 3'-end processing", "d": ["The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0014733", "l": "regulation of skeletal muscle adaptation", "d": ["Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. 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These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0043562", "l": "cellular response to nitrogen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.760981911179996", "identifiers": [{"i": "GO:0061013", "l": "regulation of mRNA catabolic process", "d": ["Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903455", "l": "negative regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007004", "l": "telomere maintenance via telomerase", "d": ["The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.796139606449842", "identifiers": [{"i": "GO:0000018", "l": "regulation of DNA recombination", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.960002279600147", "identifiers": [{"i": "GO:0072078", "l": "nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a nephron tubule are generated and organized. 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Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002672", "l": "positive regulation of B cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell anergy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0032310", "l": "prostaglandin secretion", "d": ["The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019630", "l": "quinate metabolic process", "d": ["The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042424", "l": "catecholamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904633", "l": "regulation of podocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010512", "l": "negative regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009300", "l": "antisense RNA transcription", "d": ["The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141017", "l": "effector-mediated induction of cell cycle reactivation in host", "d": ["A symbiont process in which a molecule secreted by the symbiont reactivates the host cell cycle, resulting in DNA synthesis and host cell division, and contributing to vegetative tumor formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0012502", "l": "induction of programmed cell death", "d": ["A process which directly activates any of the steps required for programmed cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0098719", "l": "sodium ion import across plasma membrane", "d": ["The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902499", "l": "positive regulation of protein autoubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein autoubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000937", "l": "negative regulation of cellotriose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019756", "l": "cyanogenic glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0097354", "l": "prenylation", "d": ["The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030394", "l": "fructoseglycine metabolic process", "d": ["The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.915586648813779", "identifiers": [{"i": "GO:0001816", "l": "cytokine production", "d": ["The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900162", "l": "negative regulation of phospholipid scramblase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060049", "l": "regulation of protein glycosylation", "d": ["Any process that modulates the frequency, rate or extent of protein glycosylation. 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UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.974037860983486", "identifiers": [{"i": "GO:0061007", "l": "hepaticobiliary system process", "d": ["An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0001834", "l": "trophectodermal cell proliferation", "d": ["The proliferation of cells in the trophectoderm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904077", "l": "negative regulation of estrogen biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.151319539368089", "identifiers": [{"i": "GO:0002312", "l": "B cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071474", "l": "cellular hyperosmotic response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0072031", "l": "proximal convoluted tubule segment 1 development", "d": ["The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. 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The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0002786", "l": "regulation of antibacterial peptide production", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0042548", "l": "regulation of photosynthesis, light reaction", "d": ["Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900100", "l": "positive regulation of plasma cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of plasma cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061108", "l": "seminal vesicle epithelium development", "d": ["The progression of the seminal vesicle epithelium over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905645", "l": "negative regulation of FACT complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.024411547311772", "identifiers": [{"i": "GO:0018209", "l": "peptidyl-serine modification", "d": ["The modification of peptidyl-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061276", "l": "mesonephric proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. 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"ic": "100", "identifiers": [{"i": "GO:0048782", "l": "negative regulation of cyanophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0043711", "l": "pilus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002860", "l": "positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed 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Differentiation includes the processes involved in commitment of a cell to a specific fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902418", "l": "(+)-abscisic acid D-glucopyranosyl ester transmembrane transport", "d": ["The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030717", "l": "oocyte karyosome formation", "d": ["The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902123", "l": "(-)-pinoresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046305", "l": "alkanesulfonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900863", "l": "positive regulation of cordyol C biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0000820", "l": "regulation of glutamine family amino acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.87435383147438", "identifiers": [{"i": "GO:0044036", "l": "cell wall macromolecule metabolic process", "d": ["The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. 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The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901694", "l": "positive regulation of compound eye retinal cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902831", "l": "positive regulation of spinal cord association neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040015", "l": "negative regulation of multicellular organism growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903949", "l": "positive regulation of atrial cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904473", "l": "response to L-dopa", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043569", "l": "negative regulation of insulin-like growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900025", "l": "negative regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048829", "l": "root cap development", "d": ["The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901099", "l": "negative regulation of signal transduction in absence of ligand", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904114", "l": "positive regulation of muscle filament sliding", "d": ["Any process that activates or increases the frequency, rate or extent of muscle filament sliding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098987", "l": "regulation of modification of synapse structure, modulating synaptic transmission", "d": ["Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900870", "l": "tatiopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tatiopterin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034077", "l": "butanediol metabolic process", "d": ["The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016031", "l": "tRNA import into mitochondrion", "d": ["The process in which a tRNA is transported from the cytosol into the mitochondrial matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000310", "l": "regulation of NMDA receptor activity", "d": ["Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905295", "l": "regulation of neural crest cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of neural crest cell fate specification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070922", "l": "RISC complex assembly", "d": ["The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:2000259", "l": "positive regulation of protein activation cascade", "d": ["Any process that activates or increases the frequency, rate or extent of protein activation cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072086", "l": "specification of loop of Henle identity", "d": ["The process in which the loop of Henle of the kidney nephron acquires its identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0019747", "l": "regulation of isoprenoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904840", "l": "positive regulation of male germ-line stem cell asymmetric division", "d": ["Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098676", "l": "modulation of host virulence by virus", "d": ["A process by which a virus improves the virulence of its host for that host's respective host. 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Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904687", "l": "positive regulation of mitotic spindle disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903132", "l": "regulation of tube lumen cavitation", "d": ["Any process that modulates the frequency, rate or extent of tube lumen cavitation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044079", "l": "modulation by symbiont of host neurotransmitter secretion", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017055", "l": "negative regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010729", "l": "positive regulation of hydrogen peroxide biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. 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Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007100", "l": "mitotic centrosome separation", "d": ["Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. 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Class I here refers to classical class I molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902777", "l": "6-sulfoquinovose(1-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060283", "l": "negative regulation of oocyte development", "d": ["Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046413", "l": "organomercury catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070164", "l": "negative regulation of adiponectin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902525", "l": "regulation of protein monoubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein monoubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045221", "l": "negative regulation of FasL production", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0071421", "l": "manganese ion transmembrane transport", "d": ["A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0098927", "l": "vesicle-mediated transport between endosomal compartments", "d": ["A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904867", "l": "protein localization to Cajal body", "d": ["A process in which a protein is transported to, or maintained in, a location within a Cajal body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0048308", "l": "organelle inheritance", "d": ["The partitioning of organelles between daughter cells at cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0035728", "l": "response to hepatocyte growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010774", "l": "meiotic strand invasion involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. 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The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106115", "l": "negative regulation of mitotic cohesin dsDNA (leading strand) loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0061525", "l": "hindgut development", "d": ["The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0018158", "l": "protein oxidation", "d": ["The modification of a protein amino acid by oxidation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0051167", "l": "xylulose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034628", "l": "'de novo' NAD biosynthetic process from aspartate", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000268", "l": "positive regulation of blood coagulation, intrinsic pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903583", "l": "positive regulation of basophil degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of basophil degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0061515", "l": "myeloid cell development", "d": ["The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903568", "l": "negative regulation of protein localization to ciliary membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031944", "l": "negative regulation of glucocorticoid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0050650", "l": "chondroitin sulfate proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010831", "l": "positive regulation of myotube differentiation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019328", "l": "anaerobic gallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904289", "l": "regulation of mitotic DNA damage checkpoint", "d": ["Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061935", "l": "fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes", "d": ["The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904109", "l": "positive regulation of cholesterol import", "d": ["Any process that activates or increases the frequency, rate or extent of cholesterol import."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033247", "l": "regulation of penicillin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0048144", "l": "fibroblast proliferation", "d": ["The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0031052", "l": "programmed DNA elimination by chromosome breakage", "d": ["Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901140", "l": "p-coumaryl alcohol transport", "d": ["The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060610", "l": "mesenchymal cell differentiation involved in mammary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904833", "l": "positive regulation of removal of superoxide radicals", "d": ["Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006867", "l": "asparagine transport", "d": ["The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0036065", "l": "fucosylation", "d": ["The covalent attachment of a fucosyl group to an acceptor molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905125", "l": "positive regulation of glucosylceramidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007317", "l": "regulation of pole plasm oskar mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0099022", "l": "vesicle tethering", "d": ["The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060842", "l": "arterial endothelial cell differentiation", "d": ["The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0003308", "l": "negative regulation of Wnt signaling pathway involved in heart development", "d": ["Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006795", "l": "regulation of phosphorus utilization", "d": ["Any process that modulates the frequency, rate or extent of phosphorus utilization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002391", "l": "platelet activating factor production involved in inflammatory response", "d": ["The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001546", "l": "preantral ovarian follicle growth", "d": ["Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140471", "l": "positive regulation of transepithelial migration of symbiont in host", "d": ["Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010663", "l": "positive regulation of striated muscle cell apoptotic process", "d": ["Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019536", "l": "vibriobactin metabolic process", "d": ["The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048917", "l": "posterior lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021940", "l": "positive regulation of cerebellar granule cell precursor proliferation", "d": ["The process that activates or increases the rate or extent of granule cell precursor proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904681", "l": "response to 3-methylcholanthrene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160086", "l": "protein localization to polar microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within a polar microtubule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000449", "l": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0033212", "l": "iron import into cell", "d": ["The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030310", "l": "poly-N-acetyllactosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0050893", "l": "sensory processing", "d": ["Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060663", "l": "apoptotic process involved in salivary gland cavitation", "d": ["Any apoptotic process in which the solid core of the gland is hollowed out to form the duct."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090611", "l": "ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0009133", "l": "nucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018228", "l": "peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000543", "l": "positive regulation of gastrulation", "d": ["Any process that activates or increases the frequency, rate or extent of gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002626", "l": "negative regulation of T cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006809", "l": "nitric oxide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010985", "l": "negative regulation of lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900548", "l": "heme B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0072155", "l": "epithelial cell migration involved in nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:1905777", "l": "regulation of exonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:2000779", "l": "regulation of double-strand break repair", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035709", "l": "memory T cell activation", "d": ["The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021968", "l": "corticospinal neuron axon guidance through the internal capsule", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0035435", "l": "phosphate ion transmembrane transport", "d": ["The process in which a phosphate is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051645", "l": "Golgi localization", "d": ["Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0060444", "l": "branching involved in mammary gland duct morphogenesis", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905035", "l": "negative regulation of antifungal innate immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098864", "l": "symbiont-mediated stabilization of host tight cell-cell junction", "d": ["The process in which a symbiont organism that stabilizes the its host tight cell-cell junctions, making them less dynamic. The tight junction is a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other, and plays a role in the inflammatory response of the host."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901968", "l": "regulation of polynucleotide 3'-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043407", "l": "negative regulation of MAP kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035688", "l": "T-helper 1 cell diapedesis", "d": ["The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0002904", "l": "positive regulation of B cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1990153", "l": "maintenance of protein localization to heterochromatin", "d": ["A process in which a protein is maintained in a location in telomeric heterochromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0031443", "l": "fast-twitch skeletal muscle fiber contraction", "d": ["A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033659", "l": "symbiont-mediated disruption of host mitochondrion", "d": ["The process in which an organism effects a change in the structure or function of host cell mitochondria. 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Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000245", "l": "negative regulation of FtsZ-dependent cytokinesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044795", "l": "trans-Golgi network to recycling endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046063", "l": "dCMP metabolic process", "d": ["The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001061", "l": "D-glycero-D-manno-heptose 7-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010820", "l": "positive regulation of T cell chemotaxis", "d": ["Any process that increases the rate, frequency or extent of T cell chemotaxis. 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Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0099084", "l": "postsynaptic specialization organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071670", "l": "smooth muscle cell chemotaxis", "d": ["The directed movement of a smooth muscle cell in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903841", "l": "cellular response to arsenite(3-)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901811", "l": "beta-carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-carotene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015969", "l": "guanosine tetraphosphate metabolic process", "d": ["The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021995", "l": "neuropore closure", "d": ["The process of joining together the neural folds at either end of the neural tube."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901057", "l": "trimethylenediamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trimethylenediamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051344", "l": "negative regulation of cyclic-nucleotide phosphodiesterase activity", "d": ["Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001143", "l": "N-methylnicotinate transport", "d": ["The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0003230", "l": "cardiac atrium development", "d": ["The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. 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A skeletal joint is the connecting structure between the bones of the skeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0050848", "l": "regulation of calcium-mediated signaling", "d": ["Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061153", "l": "trachea gland development", "d": ["The progression of a trachea gland over time, from its formation to the mature structure. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0061517", "l": "macrophage proliferation", "d": ["The expansion of a macrophage population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0050927", "l": "positive regulation of positive chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046363", "l": "ribitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.876091073600094", "identifiers": [{"i": "GO:0001707", "l": "mesoderm formation", "d": ["The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0009838", "l": "abscission", "d": ["The controlled shedding of a body part."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0002082", "l": "regulation of oxidative phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903091", "l": "pyridoxamine transmembrane transport", "d": ["The process in which pyridoxamine is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002846", "l": "regulation of T cell tolerance induction to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090444", "l": "regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018361", "l": "peptidyl-glutamine 2-methylation", "d": ["The methylation of glutamine to form 2-methyl-L-glutamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0032905", "l": "transforming growth factor beta1 production", "d": ["The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050835", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001239", "l": "regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008377", "l": "light-induced release of internally sequestered calcium ion", "d": ["The process in which the detection of light triggers the release of internally sequestered calcium ions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090424", "l": "phytochelatin-metal-sulfur complex formation", "d": ["A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003046", "l": "regulation of systemic arterial blood pressure by stress relaxation", "d": ["The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905417", "l": "negative regulation of amoeboid sperm motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002841", "l": "negative regulation of T cell mediated immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0042473", "l": "outer ear morphogenesis", "d": ["The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006849", "l": "plasma membrane pyruvate transport", "d": ["The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0032328", "l": "alanine transport", "d": ["The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002799", "l": "positive regulation of antibacterial peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.150074347456084", "identifiers": [{"i": "GO:0044848", "l": "biological phase", "d": ["A distinct period or stage in a biological process or cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900482", "l": "positive regulation of diacylglycerol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046183", "l": "L-idonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.709179502404908", "identifiers": [{"i": "GO:0061982", "l": "meiosis I cell cycle process", "d": ["A process that contributes to the first meiotic division. 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Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046307", "l": "Z-phenylacetaldoxime biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900819", "l": "orlandin metabolic process", "d": ["The chemical reactions and pathways involving orlandin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0015734", "l": "taurine transport", "d": ["The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090506", "l": "axillary shoot meristem initiation", "d": ["A developmental process that results in the initiation of an axillary shoot meristem. 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The tethering may facilitate exchange of metabolites between the organelles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0141027", "l": "symbiont-mediated perturbation of host actin cytoskeleton", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton. 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Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905766", "l": "positive regulation of protection from non-homologous end joining at telomere", "d": ["Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901716", "l": "negative regulation of gamma-aminobutyric acid catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033357", "l": "L-arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0007088", "l": "regulation of mitotic nuclear division", "d": ["Any process that modulates the frequency, rate or extent of mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901035", "l": "negative regulation of L-glutamine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0072111", "l": "cell proliferation involved in kidney development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072760", "l": "cellular response to GW 7647", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900118", "l": "negative regulation of execution phase of apoptosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031922", "l": "pyridoxamine transport", "d": ["The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003436", "l": "regulation of cell adhesion involved in growth plate cartilage morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0001992", "l": "regulation of systemic arterial blood pressure by vasopressin", "d": ["The regulation of blood pressure mediated by the signaling molecule vasopressin. 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Heart growth is the increase in size or mass of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010078", "l": "maintenance of root meristem identity", "d": ["The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901371", "l": "regulation of leaf morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of leaf morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0001117", "l": "protein-DNA-RNA complex disassembly", "d": ["The disaggregation of a protein-DNA-RNA complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.423516253190407", "identifiers": [{"i": "GO:0050881", "l": "musculoskeletal movement", "d": ["The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071278", "l": "cellular response to cesium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062123", "l": "regulation of linear element maturation", "d": ["Any process that modulates the rate, frequency or extent of linear element maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.199315133585145", "identifiers": [{"i": "GO:0002218", "l": "activation of innate immune response", "d": ["Any process that initiates an innate immune response. 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A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "45.359160501348534", "identifiers": [{"i": "GO:0051606", "l": "detection of stimulus", "d": ["The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070965", "l": "positive regulation of neutrophil mediated killing of fungus", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035202", "l": "tracheal pit formation in open tracheal system", "d": ["Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0072402", "l": "response to DNA integrity checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0086049", "l": "membrane repolarization during AV node cell action potential", "d": ["The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.79931926293068", "identifiers": [{"i": "GO:0009895", "l": "negative regulation of catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903787", "l": "negative regulation of glutathione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141066", "l": "symbiont-mediated disruption of host extracellular matrix", "d": ["The process in which an organism effects a change that impairs the structure or function of the host extracellular matrix."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0062036", "l": "sensory perception of hot stimulus", "d": ["The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1902295", "l": "synthesis of RNA primer involved in cell cycle DNA replication", "d": ["Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033529", "l": "raffinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046454", "l": "dimethylsilanediol metabolic process", "d": ["The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050838", "l": "peptidyl-5-hydroxy-L-lysine trimethylation", "d": ["The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.57655971136198", "identifiers": [{"i": "GO:0044068", "l": "symbiont-mediated perturbation of host cellular process", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032705", "l": "negative regulation of interleukin-21 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051756", "l": "meiotic sister chromatid centromere separation", "d": ["The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046880", "l": "regulation of follicle-stimulating hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036118", "l": "hyaluranon cable assembly", "d": ["A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035437", "l": "maintenance of protein localization in endoplasmic reticulum", "d": ["Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. 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A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0044621", "l": "modulation of cell migration in another organism", "d": ["The process in which an organism effects a change in the process of cell migration in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140921", "l": "negative regulation of thermomorphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thermomorphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034626", "l": "fatty acid elongation, polyunsaturated fatty acid", "d": ["Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0061037", "l": "negative regulation of cartilage development", "d": ["Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007490", "l": "tergite morphogenesis", "d": ["The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0075216", "l": "positive regulation of spore encystment on host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090361", "l": "regulation of platelet-derived growth factor production", "d": ["Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035846", "l": "oviduct epithelium development", "d": ["The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061581", "l": "corneal epithelial cell migration", "d": ["The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035761", "l": "dorsal motor nucleus of vagus nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001142", "l": "nicotinate transport", "d": ["The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035127", "l": "post-embryonic limb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015777", "l": "teichoic acid transport", "d": ["The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061072", "l": "iris morphogenesis", "d": ["The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:1903351", "l": "cellular response to dopamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106296", "l": "D-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.480207878732358", "identifiers": [{"i": "GO:0140353", "l": "lipid export from cell", "d": ["The directed movement of a lipid from a cell, 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"biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019460", "l": "glutamine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.691787587221924", "identifiers": [{"i": "GO:1903706", "l": "regulation of hemopoiesis", "d": ["Any process that modulates the frequency, rate or extent of hemopoiesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033860", "l": "regulation of NAD(P)H oxidase activity", "d": ["Any process that modulates the activity of the enzyme NAD(P)H oxidase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0048753", "l": "pigment granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0001660", "l": "fever generation", "d": ["The heat generation process that results in a rise in body temperature above the normal, often as a response to infection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070189", "l": "kynurenine metabolic process", "d": ["The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0043114", "l": "regulation of vascular permeability", "d": ["Any process that modulates the extent to which blood vessels can be pervaded by fluid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0099639", "l": "neurotransmitter receptor transport, endosome to plasma membrane", "d": ["The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001803", "l": "regulation of type III hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902289", "l": "negative regulation of defense response to oomycetes", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0042733", "l": "embryonic digit 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A digit is one of the terminal divisions of an appendage, such as a finger or toe."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043497", "l": "regulation of protein heterodimerization activity", "d": ["Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019235", "l": "sensory perception of slow pain", "d": ["The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010098", "l": "suspensor development", "d": ["The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046181", "l": "ketogluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900149", "l": "positive regulation of Schwann cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901333", "l": "positive regulation of lateral root development", "d": ["Any process that activates or increases the frequency, rate or extent of lateral root development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0016243", "l": "regulation of autophagosome size", "d": ["Any process that modulates the size of the autophagosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0000919", "l": "cell plate assembly", "d": ["The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018191", "l": "peptidyl-serine octanoylation", "d": ["The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.510159133984757", "identifiers": [{"i": "GO:1901657", "l": "glycosyl compound metabolic process", "d": ["The chemical reactions and pathways involving glycosyl compound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0007482", "l": "haltere development", "d": ["The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0071479", "l": "cellular response to ionizing radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900459", "l": "positive regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1904616", "l": "regulation of actin binding", "d": ["Any process that modulates the frequency, rate or extent of actin binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007119", "l": "budding cell isotropic bud growth", "d": ["Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018067", "l": "peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.170170386724372", "identifiers": [{"i": "GO:0042330", "l": "taxis", "d": ["The directed movement of a motile cell or organism in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903372", "l": "negative regulation of endoplasmic reticulum tubular network organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006196", "l": "AMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009152", "l": "purine ribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044838", "l": "cell quiescence", "d": ["A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043290", "l": "apocarotenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990734", "l": "astral microtubule anchoring at mitotic spindle pole body", "d": ["Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903740", "l": "positive regulation of phosphatidate phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052098", "l": "formation by host of specialized structure for nutrient acquisition from symbiont", "d": ["The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. 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For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045855", "l": "negative regulation of pole plasm oskar mRNA localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071520", "l": "actomyosin contractile ring assembly actin filament bundle convergence", "d": ["A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0002922", "l": "positive regulation of humoral immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of a humoral immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0018143", "l": "nucleic acid-protein covalent cross-linking", "d": ["The formation of a covalent cross-link between a nucleic acid and a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0042816", "l": "vitamin B6 metabolic process", "d": ["The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035260", "l": "internal genitalia morphogenesis", "d": ["The process in which the anatomical structures of the internal genitalia are generated and organized. 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STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. 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The ligand is functional when it can bind to and activate an epidermal growth factor receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0017003", "l": "protein-heme linkage", "d": ["The covalent linkage of heme and a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070414", "l": "trehalose metabolism in response to heat stress", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0043001", "l": "Golgi to plasma membrane protein transport", "d": ["The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904843", "l": "cellular response to nitroglycerin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.97739419478313", "identifiers": [{"i": "GO:0030534", "l": "adult behavior", "d": ["Behavior in a fully developed and mature organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000788", "l": "negative regulation of venous endothelial cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901499", "l": "response to hexane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0045637", "l": "regulation of myeloid cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of myeloid cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0006103", "l": "2-oxoglutarate metabolic process", "d": ["The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. 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An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904596", "l": "regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that modulates the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000743", "l": "negative regulation of anterior head development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070806", "l": "negative regulation of phialide development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030277", "l": "maintenance of gastrointestinal epithelium", "d": ["Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072444", "l": "response to mitotic DNA replication checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0030832", "l": "regulation of actin filament length", "d": ["Any process that controls the length of actin filaments in a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0051785", "l": "positive regulation of nuclear division", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905034", "l": "regulation of antifungal innate immune response", "d": ["Any process that modulates the frequency, rate or extent of an antifungal innate immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905017", "l": "positive regulation of isoleucine-tRNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0036018", "l": "cellular response to erythropoietin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048342", "l": "paraxial mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0032056", "l": "positive regulation of translation in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0090092", "l": "regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009754", "l": "detection of jasmonic acid stimulus", "d": ["The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0030512", "l": "negative regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1905771", "l": "negative regulation of mesodermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:1905214", "l": "regulation of RNA binding", "d": ["Any process that modulates the frequency, rate or extent of RNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0006696", "l": "ergosterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014813", "l": "skeletal muscle satellite cell commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0006690", "l": "icosanoid metabolic process", "d": ["The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085001", "l": "formation of stylet for nutrient acquisition", "d": ["The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0080186", "l": "developmental vegetative growth", "d": ["The increase in size or mass of non-reproductive plant parts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046300", "l": "2,4-dichlorophenoxyacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0061774", "l": "cohesin unloading", "d": ["Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0110003", "l": "regulation of tRNA C5-cytosine methylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071529", "l": "cementum mineralization", "d": ["The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042711", "l": "maternal behavior", "d": ["Female behaviors associated with the care and rearing of offspring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021815", "l": "modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration", "d": ["Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019558", "l": "histidine catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990227", "l": "paranodal junction maintenance", "d": ["The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905888", "l": "negative regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033485", "l": "cyanidin 3-O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902263", "l": "apoptotic process involved in embryonic digit morphogenesis", "d": ["Any apoptotic process that is involved in embryonic digit morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.976681203957298", "identifiers": [{"i": "GO:0001708", "l": "cell fate specification", "d": ["The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902846", "l": "positive regulation of mitotic spindle elongation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.976681203957298", "identifiers": [{"i": "GO:0042593", "l": "glucose homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of glucose within an organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021643", "l": "vagus nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043317", "l": "regulation of cytotoxic T cell degranulation", "d": ["Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0006303", "l": "double-strand break repair via nonhomologous end joining", "d": ["The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007026", "l": "negative regulation of microtubule depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018957", "l": "phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0015948", "l": "methanogenesis", "d": ["The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051945", "l": "negative regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "43.414557767851832", "identifiers": [{"i": "GO:0008283", "l": "cell population proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900598", "l": "demethylkotanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of demethylkotanin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900347", "l": "positive regulation of methane biosynthetic process from methanethiol", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021992", "l": "cell proliferation involved in neural plate elongation", "d": ["The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010524", "l": "positive regulation of calcium ion transport into cytosol", "d": ["Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. 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An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.593242189043409", "identifiers": [{"i": "GO:0046541", "l": "saliva secretion", "d": ["The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003245", "l": "cardiac muscle tissue growth involved in heart morphogenesis", "d": ["The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900327", "l": "regulation of mannotriose transport", "d": ["Any process that modulates the frequency, rate or extent of mannotriose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071960", "l": "maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051633", "l": "positive regulation of acetylcholine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034139", "l": "regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0022007", "l": "convergent extension involved in neural plate elongation", "d": ["The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035297", "l": "regulation of Malpighian tubule diameter", "d": ["Ensuring that the Malpighian tubule is the correct width. 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Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009172", "l": "purine deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0150117", "l": "positive regulation of cell-substrate junction organization", "d": ["Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070809", "l": "negative regulation of Hulle cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0022616", "l": "DNA strand elongation", "d": ["The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0005990", "l": "lactose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0046629", "l": "gamma-delta T cell activation", "d": ["The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060927", "l": "cardiac pacemaker cell fate commitment", "d": ["The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. 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Class I here refers to classical class I molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000684", "l": "negative regulation of cellular response to X-ray", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045989", "l": "positive regulation of striated muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.503937487960073", "identifiers": [{"i": "GO:0010639", "l": "negative regulation of organelle organization", "d": ["Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904830", "l": "negative regulation of aortic smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061413", "l": "regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source", "d": ["A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1901343", "l": "negative regulation of vasculature development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0070793", "l": "regulation of conidiophore development", "d": ["Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0052482", "l": "defense response by cell wall thickening", "d": ["A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.868301077661471", "identifiers": [{"i": "GO:0015918", "l": "sterol transport", "d": ["The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060772", "l": "leaf phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050689", "l": "negative regulation of defense response to virus by host", "d": ["Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0002884", "l": "negative regulation of hypersensitivity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031953", "l": "negative regulation of protein autophosphorylation", "d": ["Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009831", "l": "plant-type cell wall modification involved in multidimensional cell growth", "d": ["The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. 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dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:1902983", "l": "DNA strand elongation involved in mitotic DNA replication", "d": ["Any DNA strand elongation involved in mitotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901283", "l": "5,6,7,8-tetrahydromethanopterin metabolic process", "d": ["The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0015916", "l": "fatty-acyl-CoA transport", "d": ["The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900805", "l": "brevianamide F biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of brevianamide F. 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Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0010811", "l": "positive regulation of cell-substrate adhesion", "d": ["Any process that increases the frequency, rate or extent of cell-substrate adhesion. 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Evoked transmission starts with the arrival of an action potential at the presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905943", "l": "negative regulation of formation of growth cone in injured axon", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0075198", "l": "modulation of symbiont haustorium neck formation for entry into host", "d": ["Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. 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Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060647", "l": "mesenchymal cell condensation involved in mammary fat development", "d": ["The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:2000855", "l": "regulation of mineralocorticoid secretion", "d": ["Any process that modulates the frequency, rate or extent of mineralocorticoid secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904984", "l": "regulation of quinolinate biosynthetic process", "d": ["Any process that modulates the frequency, 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042333", "l": "chemotaxis to oxidizable substrate", "d": ["The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000491", "l": "small nucleolar ribonucleoprotein complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010067", "l": "procambium histogenesis", "d": ["The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045961", "l": "negative 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"GO:0046382", "l": "GDP-D-rhamnose metabolic process", "d": ["The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.014330232248525", "identifiers": [{"i": "GO:0052173", "l": "response to defenses of other organism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902542", "l": "regulation of protein localization to mitotic spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": 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during atrial cardiac muscle cell action potential", "d": ["The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039010", "l": "specification of pronephric distal tubule identity", "d": ["The process in which the distal tubule of the pronephric nephron acquires its identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061853", "l": "regulation of neuroblast migration", "d": ["Any process that modulates the frequency, rate or extent of neuroblast migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000174", "l": "regulation of pro-T cell differentiation", "d": 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Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000711", "l": "meiotic DNA repair synthesis", "d": ["During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0006063", "l": "uronic acid metabolic process", "d": ["The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904445", "l": "negative regulation of establishment of Sertoli cell barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0010393", "l": "galacturonan metabolic process", "d": ["The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901271", "l": "lipooligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipooligosaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0141142", "l": "symbiont-mediated migration across host tissue barrier", "d": ["A process in which a symbiont moves across a tissue barrier of the host to transports itself across an extracellular cellular matrix barrier or between cells. 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This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905590", "l": "fibronectin fibril organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.82716154794511", "identifiers": [{"i": "GO:0010564", "l": "regulation of cell cycle process", "d": ["Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0000002", "l": "mitochondrial genome maintenance", "d": ["The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905386", "l": "positive regulation of protein localization to presynapse", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048047", "l": "mating behavior, sex discrimination", "d": ["The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090393", "l": "sepal giant cell development", "d": ["The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990969", "l": "modulation by host of viral RNA-binding transcription factor activity", "d": ["A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990764", "l": "myofibroblast contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0080184", "l": "response to phenylpropanoid", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000717", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, arms", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051711", "l": "negative regulation of killing of cells of another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010808", "l": "positive regulation of synaptic vesicle priming", "d": ["Any process that increases the frequency, rate or extent of synaptic vesicle priming. 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It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0030497", "l": "fatty acid elongation", "d": ["The elongation of a fatty acid chain by the sequential addition of two-carbon units."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015806", "l": "S-methylmethionine transport", "d": ["The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072631", "l": "interleukin-29 production", "d": ["The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048392", "l": "intermediate mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903966", "l": "monounsaturated fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042862", "l": "achromobactin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.474770398704251", "identifiers": [{"i": "GO:0002703", "l": "regulation of leukocyte mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0110012", "l": "protein localization to P-body", "d": ["Any process in which a protein is transported to, or maintained at, a P-body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035018", "l": "adult chitin-based cuticle pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. 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Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903567", "l": "regulation of protein localization to ciliary membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042635", "l": "positive regulation of hair cycle", "d": ["Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015897", "l": "organomercurial transport", "d": ["The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002130", "l": "wobble position ribose methylation", "d": ["The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905558", "l": "negative regulation of mitotic nuclear envelope disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003261", "l": "cardiac muscle progenitor cell migration to the midline involved in heart field formation", "d": ["The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090668", "l": "endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905827", "l": "positive regulation of selenocysteine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1904555", "l": "L-proline transmembrane transport", "d": ["The directed movement of L-proline across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990280", "l": "RNA localization to chromatin", "d": ["A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045973", "l": "positive regulation of juvenile hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106046", "l": "guanine deglycation, glyoxal removal", "d": ["The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044479", "l": "envenomation resulting in modulation of mast cell degranulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048924", "l": "posterior lateral line neuromast mantle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034035", "l": "purine ribonucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.569731477099452", "identifiers": [{"i": "GO:0001525", "l": "angiogenesis", "d": ["Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035052", "l": "dorsal vessel aortic cell fate commitment", "d": ["The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099577", "l": "regulation of translation at presynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904133", "l": "regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901508", "l": "positive regulation of acylglycerol transport", "d": ["Any process that activates or increases the frequency, rate or extent of acylglycerol transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905654", "l": "regulation of artery smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of artery smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010364", "l": "regulation of ethylene biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010615", "l": "positive regulation of cardiac muscle adaptation", "d": ["Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002409", "l": "Langerhans cell chemotaxis", "d": ["The movement of a Langerhans cell in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903931", "l": "positive regulation of pyrimidine-containing compound salvage", "d": ["Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051410", "l": "detoxification of nitrogen compound", "d": ["Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140145", "l": "copper ion export from vacuole", "d": ["The directed movement of copper ions out of the vacuole across the vacuolar membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072513", "l": "positive regulation of secondary heart field cardioblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016319", "l": "mushroom body development", "d": ["The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901902", "l": "tyrocidine metabolic process", "d": ["The chemical reactions and pathways involving tyrocidine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021960", "l": "anterior commissure morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1903867", "l": "extraembryonic membrane development", "d": ["The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072068", "l": "late distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902614", "l": "positive regulation of anti-Mullerian hormone signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070689", "l": "L-threonine catabolic process to propionate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045594", "l": "positive regulation of cumulus cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0033108", "l": "mitochondrial respiratory chain complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902334", "l": "fructose export from vacuole to cytoplasm", "d": ["The directed movement of fructose from vacuole to cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903973", "l": "negative regulation of cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1902486", "l": "protein localization to growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a growing cell tip."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0075310", "l": "regulation of sporangium development", "d": ["Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010935", "l": "regulation of macrophage cytokine production", "d": ["Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051518", "l": "positive regulation of bipolar cell growth", "d": ["Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021702", "l": "cerebellar Purkinje cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002150", "l": "hypochlorous acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hypochlorous acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904443", "l": "positive regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0140541", "l": "piRNA transcription", "d": ["The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034478", "l": "phosphatidylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.014330232248525", "identifiers": [{"i": "GO:0043549", "l": "regulation of kinase activity", "d": ["Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000692", "l": "negative regulation of seed maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072300", "l": "positive regulation of metanephric glomerulus development", "d": ["Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1900193", "l": "regulation of oocyte maturation", "d": ["Any process that modulates the frequency, rate or extent of oocyte maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0032329", "l": "serine transport", "d": ["The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0009130", "l": "pyrimidine nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0071902", "l": "positive regulation of protein serine/threonine kinase activity", "d": ["Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0052699", "l": "ergothioneine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905173", "l": "eukaryotic translation initiation factor 2B complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902629", "l": "regulation of mRNA stability involved in cellular response to UV", "d": ["Any regulation of mRNA stability that is involved in cellular response to UV."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0040025", "l": "vulval development", "d": ["The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007449", "l": "proximal/distal pattern formation, imaginal disc", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000187", "l": "positive regulation of phosphate transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071727", "l": "cellular response to triacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0034332", "l": "adherens junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0036093", "l": "germ cell proliferation", "d": ["The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901935", "l": "beta-caryophyllene metabolic process", "d": ["The chemical reactions and pathways involving beta-caryophyllene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051659", "l": "maintenance of mitochondrion location", "d": ["Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001543", "l": "ovarian follicle rupture", "d": ["Disruption of theca cell layer releasing follicular fluid and/or the oocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071770", "l": "DIM/DIP cell wall layer assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002304", "l": "gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903944", "l": "negative regulation of hepatocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.348834789597348", "identifiers": [{"i": "GO:0046637", "l": "regulation of alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009186", "l": "deoxyribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036350", "l": "mannose-specific flocculation", "d": ["The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052784", "l": "reuteran biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0051975", "l": "lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0002413", "l": "tolerance induction to tumor cell", "d": ["A process of tolerance induction which leads to immunological tolerance of a tumor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0036506", "l": "maintenance of unfolded protein", "d": ["Maintaining a protein in an unfolded, soluble state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901554", "l": "response to paracetamol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140755", "l": "reorganization of host cellular membranes to establish sites of replication", "d": ["A process in which a virus triggers host intracellular membranes to be reorganized, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009720", "l": "detection of hormone stimulus", "d": ["The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018063", "l": "cytochrome c-heme linkage", "d": ["The linkage of cytochromes and other heme proteins to heme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000971", "l": "tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate", "d": ["A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072187", "l": "metanephric cap formation", "d": ["The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010904", "l": "regulation of UDP-glucose catabolic process", "d": ["Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. 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The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009689", "l": "induction of phytoalexin biosynthetic process", "d": ["The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051862", "l": "translocation of molecules into symbiont", "d": ["The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904041", "l": "regulation of cystathionine beta-synthase activity", "d": ["Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070731", "l": "cGMP transport", "d": ["The directed movement of cyclic GMP (cGMP), into, out of or within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060957", "l": "endocardial cell fate commitment", "d": ["The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. 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As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061925", "l": "negative regulation of formation of radial glial scaffolds", "d": ["Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140539", "l": "regulation of melanotic encapsulation of foreign target", "d": ["Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:0043039", "l": "tRNA aminoacylation", "d": ["The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. 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It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902888", "l": "protein localization to astral microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within an astral microtubule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000718", "l": "nucleotide-excision repair, DNA damage removal", "d": ["The removal of the oligonucleotide that contains the DNA damage. 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An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097388", "l": "chemokine (C-C motif) ligand 19 production", "d": ["The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048769", "l": "sarcomerogenesis", "d": ["The process in which sarcomeres are added in series within a fiber."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035995", "l": "detection of muscle stretch", "d": ["The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0072530", "l": "purine-containing compound transmembrane transport", "d": ["The process in which a purine-containing compound is transported across a membrane. 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The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001284", "l": "regulation of BMP secretion", "d": ["Any process that modulates the frequency, rate or extent of BMP secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905865", "l": "negative regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090024", "l": "negative regulation of neutrophil chemotaxis", "d": ["Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120056", "l": "large intestinal transit", "d": ["Migration of ingested material along the length of the large intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0006306", "l": "DNA methylation", "d": ["The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903272", "l": "positive regulation of cytoplasmic translational elongation through polyproline stretches", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902628", "l": "positive regulation of assembly of large subunit precursor of preribosome", "d": ["Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902068", "l": "regulation of sphingolipid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of sphingolipid signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0021895", "l": "cerebral cortex neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052696", "l": "flavonoid glucuronidation", "d": ["The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901984", "l": "negative regulation of protein acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0007538", "l": "primary sex determination", "d": ["The sex determination process that results in the initial specification of sexual status of an individual organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035142", "l": "dorsal fin morphogenesis", "d": ["The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140242", "l": "translation at postsynapse", "d": ["Translation that occurs at the postsynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900263", "l": "negative regulation of DNA-directed DNA polymerase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071227", "l": "cellular response to molecule of oomycetes origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905611", "l": "negative regulation of mRNA cap binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045651", "l": "positive regulation of macrophage differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902520", "l": "response to doxorubicin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000454", "l": "positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000464", "l": "endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990775", "l": "endothelin production", "d": ["The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032462", "l": "regulation of protein homooligomerization", "d": ["Any process that modulates the frequency, rate or extent of protein homooligomerization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0007304", "l": "chorion-containing eggshell formation", "d": ["The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048939", "l": "anterior lateral line nerve glial cell development", "d": ["The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0034059", "l": "response to anoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010104", "l": "regulation of ethylene-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019128", "l": "peptidyl-tryptophan racemization", "d": ["The racemization of peptidyl-tryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140041", "l": "cellular detoxification of methylglyoxal", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. 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An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1990437", "l": "snRNA 2'-O-methylation", "d": ["The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903497", "l": "cellular response to 11-deoxycorticosterone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901828", "l": "zeaxanthin bis(beta-D-glucoside) metabolic process", "d": ["The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019621", "l": "creatinine catabolic process to formate", "d": ["The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003187", "l": "ventriculo bulbo valve morphogenesis", "d": ["The process in which the structure of the ventriculo bulbo valve is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021904", "l": "dorsal/ventral neural tube patterning", "d": ["The process in which the neural tube is regionalized in the dorsoventral axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901923", "l": "negative regulation of sclerotium development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061385", "l": "fibroblast proliferation involved in heart morphogenesis", "d": ["The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0043102", "l": "amino acid salvage", "d": ["Any process which produces an amino acid from derivatives of it, without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018161", "l": "dipyrrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0033564", "l": "anterior/posterior axon guidance", "d": ["The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901743", "l": "2-deoxystreptamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019529", "l": "taurine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052645", "l": "F420-0 metabolic process", "d": ["The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0048937", "l": "lateral line nerve glial cell development", "d": ["The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097113", "l": "AMPA glutamate receptor clustering", "d": ["The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1905215", "l": "negative regulation of RNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060408", "l": "regulation of acetylcholine metabolic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048802", "l": "notum morphogenesis", "d": ["The process in which the anatomical structures of the dorsal part of the body are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0032951", "l": "regulation of beta-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904200", "l": "iodide transmembrane transport", "d": ["The process in which iodide is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0099552", "l": "trans-synaptic signaling by lipid, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019607", "l": "phenylethylamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036047", "l": "peptidyl-lysine demalonylation", "d": ["The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051695", "l": "actin filament uncapping", "d": ["The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060641", "l": "mammary gland duct regression in males", "d": ["The process in which the epithelium of the mammary duct is destroyed in males."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0006739", "l": "NADP metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0061318", "l": "renal filtration cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1903426", "l": "regulation of reactive oxygen species biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903267", "l": "negative regulation of ornithine catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032647", "l": "regulation of interferon-alpha production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-alpha production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902086", "l": "fumagillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumagillin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0060191", "l": "regulation of lipase activity", "d": ["Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010875", "l": "positive regulation of cholesterol efflux", "d": ["Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075137", "l": "response to host redox environment", "d": ["Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902964", "l": "positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904778", "l": "positive regulation of protein localization to cell cortex", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0002709", "l": "regulation of T cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048171", "l": "negative regulation of long-term neuronal synaptic plasticity", "d": ["A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. 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The dermatome is the portion of a somite that will form skin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001226", "l": "negative regulation of chloride transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021973", "l": "corticospinal neuron axon decussation", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.672771840408203", "identifiers": [{"i": "GO:0051100", "l": "negative regulation of binding", "d": ["Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019921", "l": "peptidyl-1-thioglycine biosynthetic process, carboxy-terminal", "d": ["The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048161", "l": "double layer follicle stage", "d": ["The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. 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The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034243", "l": "regulation of transcription elongation by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034695", "l": "response to prostaglandin E", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035919", "l": "negative regulation of low voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. 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Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. 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This process also regulates skeletal muscle adapatation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043272", "l": "ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance", "d": ["The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000757", "l": "negative regulation of peptidyl-lysine acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072240", "l": "metanephric DCT cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0032527", "l": "protein exit from endoplasmic reticulum", "d": ["The directed movement of proteins from the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031427", "l": "response to methotrexate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. 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It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099087", "l": "anterograde axonal transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071042", "l": "nuclear polyadenylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140913", "l": "viral release via disruption of host peptidoglycan cell wall", "d": ["The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. 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"identifiers": [{"i": "GO:0042491", "l": "inner ear auditory receptor cell differentiation", "d": ["The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033303", "l": "quercetin O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060890", "l": "limb spinous cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.848386238119481", "identifiers": [{"i": "GO:1901700", "l": "response to oxygen-containing compound", "d": ["Any process that results in a 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process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0045876", "l": "positive regulation of sister chromatid cohesion", "d": ["Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901684", "l": "arsenate ion transmembrane transport", "d": ["The process in which arsenate is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902384", "l": "glycyrrhetinate metabolic process", "d": ["The chemical reactions and pathways involving glycyrrhetinate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014839", "l": "myoblast migration involved in skeletal muscle regeneration", "d": ["The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019860", "l": "uracil metabolic process", "d": ["The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062195", "l": "microtubule bundle maintenance", "d": ["The organization process that preserves a microtubule bundle in a stable functional or structural state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901413", "l": "regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071249", "l": "cellular response to nitrate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045689", "l": "negative regulation of antipodal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018386", "l": "N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine", "d": ["The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990831", "l": "cellular response to carcinoembryonic antigen", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. 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The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0021941", "l": "negative regulation of cerebellar granule cell precursor proliferation", "d": ["The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0050844", "l": "peptidyl-selenocysteine modification", "d": ["The modification of peptidyl-selenocysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001223", "l": "negative regulation of neuron migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901809", "l": "capsanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of capsanthin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905338", "l": "negative regulation of cohesin unloading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0006406", "l": "mRNA export from nucleus", "d": ["The directed movement of mRNA from the nucleus to the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014715", "l": "myoblast fate commitment in trunk", "d": ["The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. 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The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900290", "l": "positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030264", "l": "nuclear fragmentation involved in apoptotic nuclear change", "d": ["The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900553", "l": "asperfuranone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asperfuranone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061132", "l": "pancreas induction", "d": ["The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902939", "l": "negative regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904160", "l": "protein localization to chloroplast starch grain", "d": ["A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.718781421649261", "identifiers": [{"i": "GO:0006820", "l": "monoatomic anion transport", "d": ["The directed movement of a monoatomic anion, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0010823", "l": "negative regulation of mitochondrion organization", "d": ["Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990114", "l": "RNA polymerase II core complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033686", "l": "positive regulation of luteinizing hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1904359", "l": "regulation of spore germination", "d": ["Any process that modulates the frequency, rate or extent of spore germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902155", "l": "regulation of response to G1 DNA damage checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.201143870267188", "identifiers": [{"i": "GO:1901503", "l": "ether biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ether."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072134", "l": "nephrogenic mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. 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Docking requires only that the proteins come close enough to interact and adhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048148", "l": "behavioral response to cocaine", "d": ["Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901786", "l": "p-cresol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-cresol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019442", "l": "tryptophan catabolic process to acetyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905430", "l": "cellular response to glycine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016561", "l": "protein import into peroxisome matrix, translocation", "d": ["The process in which proteins are moved across the peroxisomal membrane into the matrix. 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The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140076", "l": "negative regulation of lipoprotein transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090459", "l": "intracellular aspartate homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of aspartate within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090209", "l": "negative regulation of triglyceride metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000262", "l": "positive regulation of blood coagulation, common pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006965", "l": "positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010865", "l": "stipule development", "d": ["The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. 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The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:1901804", "l": "beta-glucoside metabolic process", "d": ["The chemical reactions and pathways involving beta-glucoside."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.876091073600094", "identifiers": [{"i": "GO:0019336", "l": "phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.33826728305938", "identifiers": [{"i": "GO:0002437", "l": "inflammatory response to antigenic stimulus", "d": ["An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990946", "l": "meiosis I/meiosis II transition", "d": ["The cell cycle process in which a cell progresses from meiosis I to meiosis II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.551441031963407", "identifiers": [{"i": "GO:0002705", "l": "positive regulation of leukocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048942", "l": "posterior lateral line nerve glial cell morphogenesis involved in differentiation", "d": ["The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. 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This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032900", "l": "negative regulation of neurotrophin production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060056", "l": "mammary gland involution", "d": ["The tissue remodeling that removes differentiated mammary epithelia during weaning."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060768", "l": "regulation of epithelial cell proliferation involved in prostate gland development", "d": ["Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.760981911179996", "identifiers": [{"i": "GO:0035850", "l": "epithelial cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0007621", "l": "negative regulation of female receptivity", "d": ["Any process that stops, prevents or reduces the receptiveness of a female to male advances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0045577", "l": "regulation of B cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of B cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0001914", "l": "regulation of T cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140217", "l": "positive regulation of D-aspartate import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048349", "l": "regulation of paraxial mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002746", "l": "antigen processing and presentation following pinocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009630", "l": "gravitropism", "d": ["The orientation of plant parts under the stimulation of gravity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0070871", "l": "cell wall organization involved in conjugation with cellular fusion", "d": ["A process of cell wall organization that contributes to conjugation with cellular fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0043388", "l": "positive regulation of DNA binding", "d": ["Any process that increases the frequency, rate or extent of DNA binding. 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Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000380", "l": "alternative mRNA splicing, via spliceosome", "d": ["The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030721", "l": "spectrosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000773", "l": "negative regulation of cellular senescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048209", "l": "regulation of vesicle targeting, to, from or within Golgi", "d": ["Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140114", "l": "cellular detoxification of fluoride", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. 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This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. 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This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140052", "l": "cellular response to oxidised low-density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046151", "l": "eye pigment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010479", "l": "stele development", "d": ["The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. 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In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018962", "l": "3-phenylpropionate metabolic process", "d": ["The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034014", "l": "response to triglyceride", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0034313", "l": "diol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048761", "l": "collenchyma cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. 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"GO:0051055", "l": "negative regulation of lipid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033672", "l": "positive regulation of NAD+ kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904239", "l": "regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001120", "l": "protein-DNA complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048190", "l": "wing disc dorsal/ventral pattern formation", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080136", "l": "priming of cellular response to stress", "d": ["The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045902", "l": "negative regulation of translational 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frequency, rate or extent of barbed-end actin filament capping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009910", "l": "negative regulation of flower development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of flower development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001196", "l": "positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0097206", "l": "nephrocyte filtration", "d": ["The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane 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"biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0002578", "l": "negative regulation of antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901530", "l": "response to hypochlorite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006533", "l": "aspartate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901631", "l": "positive regulation of presynaptic membrane organization", "d": ["Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905271", "l": "regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035713", "l": "response to nitrogen dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.126200859969501", "identifiers": [{"i": "GO:0009070", "l": "serine family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014893", "l": "response to rest involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0003334", "l": "keratinocyte development", "d": ["The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0120188", "l": "regulation of bile acid secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006422", "l": "aspartyl-tRNA aminoacylation", "d": ["The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903722", "l": "regulation of centriole elongation", "d": ["Any process that modulates the frequency, rate or extent of centriole elongation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031456", "l": "glycine betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048773", "l": "erythrophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035544", "l": "negative regulation of SNARE complex assembly", "d": ["Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. 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Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.572956221997167", "identifiers": [{"i": "GO:0034655", "l": "nucleobase-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0032986", "l": "protein-DNA complex disassembly", "d": ["The disaggregation of a protein-DNA complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060739", "l": "mesenchymal-epithelial cell signaling involved in prostate gland development", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0090199", "l": "regulation of release of cytochrome c from mitochondria", "d": ["Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055047", "l": "generative cell mitosis", "d": ["The process in which the generative cell divides by mitosis to form two haploid cells. 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One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. 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This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0008053", "l": "mitochondrial fusion", "d": ["Merging of two or more mitochondria within a cell to form a single compartment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0035904", "l": "aorta development", "d": ["The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019228", "l": "neuronal action potential", "d": ["An action potential that occurs in a neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046622", "l": "positive regulation of organ growth", "d": ["Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046040", "l": "IMP metabolic process", "d": ["The chemical reactions and pathways involving IMP, inosine monophosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902265", "l": "abscisic acid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010777", "l": "meiotic mismatch repair involved in reciprocal meiotic recombination", "d": ["A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. 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The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007451", "l": "dorsal/ventral lineage restriction, imaginal disc", "d": ["Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990555", "l": "mitochondrial oxaloacetate transmembrane transport", "d": ["The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097753", "l": "membrane bending", "d": ["A membrane organization process resulting in the bending of a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010426", "l": "DNA methylation on cytosine within a CHH sequence", "d": ["The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. 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The trochlear nerve innervates the superior oblique muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036494", "l": "positive regulation of translation initiation in response to endoplasmic reticulum stress", "d": ["Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:1901401", "l": "regulation of tetrapyrrole metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901919", "l": "positive regulation of exoribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of exoribonuclease activity."], "t": 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The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070625", "l": "zymogen granule exocytosis", "d": ["The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090639", "l": "phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol", "d": ["The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046477", "l": "glycosylceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110032", "l": "positive regulation of G2/MI transition of meiotic cell cycle", "d": ["Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0071336", "l": "regulation of hair follicle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hair follicle cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014703", "l": "oscillatory muscle contraction", "d": ["A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. 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Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006788", "l": "heme oxidation", "d": ["The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051029", "l": "rRNA transport", "d": ["The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010743", "l": "regulation of macrophage derived foam cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. 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In a two-pass circulatory system blood passes twice through the heart to supply the body once."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014730", "l": "skeletal muscle regeneration at neuromuscular junction", "d": ["The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032254", "l": "establishment of secretory granule localization", "d": ["The directed movement of a secretory granule to a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0021603", "l": "cranial nerve formation", "d": ["The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0048292", "l": "isotype switching to IgD isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.593242189043409", "identifiers": [{"i": "GO:0051054", "l": "positive regulation of DNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900140", "l": "regulation of seedling development", "d": ["Any process that modulates the frequency, rate or extent of seedling development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901404", "l": "regulation of tetrapyrrole catabolic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0048278", "l": "vesicle docking", "d": ["The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0033696", "l": "heterochromatin boundary formation", "d": ["A process that forms a boundary that limits the spreading of heterochromatin along a chromosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003367", "l": "cell-cell adhesion involved in ameboidal cell migration", "d": ["The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904253", "l": "positive regulation of bile acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of bile acid metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003115", "l": "regulation of vasoconstriction by epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003162", "l": "atrioventricular node development", "d": ["The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904348", "l": "negative regulation of small intestine smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902134", "l": "(+)-secoisolariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018899", "l": "1,2-dichloroethane metabolic process", "d": ["The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901087", "l": "benzylpenicillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzylpenicillin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060300", "l": "regulation of cytokine activity", "d": ["Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072058", "l": "outer stripe development", "d": ["The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. 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The gut is the region of the digestive tract extending from the beginning of the intestines to the anus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.875378082774276", "identifiers": [{"i": "GO:0003009", "l": "skeletal muscle contraction", "d": ["A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0034238", "l": "macrophage fusion", "d": ["The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0046364", "l": "monosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050985", "l": "peptidyl-threonine sulfation", "d": ["The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034155", "l": "regulation of toll-like receptor 7 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045975", "l": "positive regulation of translation, ncRNA-mediated", "d": ["Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000034", "l": "regulation of seed maturation", "d": ["Any process that modulates the frequency, rate or extent of seed maturation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106383", "l": "dAMP salvage", "d": ["Any process which produces a dAMP from derivatives of it, without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009920", "l": "cell plate formation involved in plant-type cell wall biogenesis", "d": ["The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0061642", "l": "chemoattraction of axon", "d": ["The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903049", "l": "negative regulation of acetylcholine-gated cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060577", "l": "pulmonary vein morphogenesis", "d": ["The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. 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An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033131", "l": "regulation of glucokinase activity", "d": ["Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043012", "l": "regulation of fusion of sperm to egg plasma membrane", "d": ["Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904246", "l": "negative regulation of polynucleotide adenylyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900023", "l": "positive regulation of D-erythro-sphingosine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035646", "l": "endosome to melanosome transport", "d": ["The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070756", "l": "positive regulation of interleukin-35 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-35 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046244", "l": "salicylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071492", "l": "cellular response to UV-A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032536", "l": "regulation of cell projection size", "d": ["A process that modulates the size of a cell projection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032215", "l": "positive regulation of telomere maintenance via semi-conservative replication", "d": ["Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0016525", "l": "negative regulation of angiogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901710", "l": "regulation of homoserine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of homoserine biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1902575", "l": "protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly", "d": ["Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0032197", "l": "retrotransposition", "d": ["A type of transposition in which a transposable element (transposon) copies and pastes itself into a different genomic location by transcription and convertsion of the transcribed RNA back into DNA through reverse transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.381375822019876", "identifiers": [{"i": "GO:0009966", "l": "regulation of signal transduction", "d": ["Any process that modulates the frequency, rate or extent of signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001212", "l": "regulation of vasculogenesis", "d": ["Any process that modulates the frequency, rate or extent of vasculogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075220", "l": "positive regulation of zoospore encystment on host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032480", "l": "negative regulation of type I interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030150", "l": "protein import into mitochondrial matrix", "d": ["The import of proteins across the outer and inner mitochondrial membranes into the matrix. 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Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0010172", "l": "embryonic body morphogenesis", "d": ["The process in which the anatomical structures of the embryonic soma are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042353", "l": "fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032082", "l": "negative regulation of type III site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072166", "l": "posterior mesonephric tubule development", "d": ["The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. 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This process is achieved via signaling in the sympathetic nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903196", "l": "negative regulation of L-dopa biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071397", "l": "cellular response to cholesterol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905711", "l": "response to phosphatidylethanolamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046057", "l": "dADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0021586", "l": "pons maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. 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"ic": "100", "identifiers": [{"i": "GO:1900283", "l": "negative regulation of cellobiose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.731030655927583", "identifiers": [{"i": "GO:0050976", "l": "detection of mechanical stimulus involved in sensory perception of touch", "d": ["The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900581", "l": "(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140548", "l": 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Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060375", "l": "regulation of mast cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. 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Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0019287", "l": "isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900968", "l": "regulation of sarcinapterin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060922", "l": "atrioventricular node cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030947", "l": "regulation of vascular endothelial growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902208", "l": "regulation of bacterial-type flagellum assembly", "d": ["Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046254", "l": "anaerobic toluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0016332", "l": "establishment or maintenance of polarity of embryonic epithelium", "d": ["Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044581", "l": "butyryl-CoA catabolic process to butyrate", "d": ["The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039563", "l": "symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity", "d": ["A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0006450", "l": "regulation of translational fidelity", "d": ["Any process that modulates the ability of the translational apparatus to interpret the genetic code."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032468", "l": "Golgi calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021554", "l": "optic nerve development", "d": ["The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903041", "l": "regulation of chondrocyte hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046753", "l": "non-lytic viral release", "d": ["The exit of a viral particle from a host cell that does not involve cell lysis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003021", "l": "detection of increased carbon dioxide by chemoreceptor signaling", "d": ["The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098795", "l": "global gene silencing by mRNA cleavage", "d": ["A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.4351281647644", "identifiers": [{"i": "GO:1901615", "l": "organic hydroxy compound metabolic process", "d": ["The chemical reactions and pathways involving organic hydroxy compound."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033605", "l": "positive regulation of catecholamine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0010454", "l": "negative regulation of cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. 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A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021851", "l": "neuroblast division in dorsal lateral ganglionic eminence", "d": ["The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045039", "l": "protein insertion into mitochondrial inner membrane", "d": ["The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010336", "l": "gibberellic acid homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900891", "l": "negative regulation of pentadecane metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000015", "l": "regulation of determination of dorsal identity", "d": ["Any process that modulates the frequency, rate or extent of determination of dorsal identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001829", "l": "trophectodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:1905331", "l": "negative regulation of morphogenesis of an epithelium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900730", "l": "negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.325027496665193", "identifiers": [{"i": "GO:0030334", "l": "regulation of cell migration", "d": ["Any process that modulates the frequency, rate or extent of cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0070972", "l": "protein localization to endoplasmic reticulum", "d": ["A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080126", "l": "ovary septum development", "d": ["The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901521", "l": "aspyridone B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aspyridone B."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0000715", "l": "nucleotide-excision repair, DNA damage recognition", "d": ["The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. 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"identifiers": [{"i": "GO:0009701", "l": "isoflavonoid phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990146", "l": "protein localization to rhabdomere", "d": ["A process in which a protein is transported to, or maintained in, a location within a rhabdomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019308", "l": "dTDP-mannose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate."], "t": []}], "taxa": []} {"type": 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Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:1905819", "l": "negative regulation of chromosome separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903906", "l": "regulation of plasma membrane raft polarization", "d": ["Any process that modulates the frequency, rate or extent of plasma membrane raft polarization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0048318", "l": "axial mesoderm development", "d": ["The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. 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the D-enantiomer of allo-hexose, an aldohexose similar to glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030321", "l": "transepithelial chloride transport", "d": ["The directed movement of chloride ions from one side of an epithelium to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0018277", "l": "protein deamination", "d": ["The removal of an amino group from a protein amino acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903548", "l": "negative regulation of growth hormone activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1901421", "l": "positive regulation of response to alcohol", "d": ["Any 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"biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0006528", "l": "asparagine metabolic process", "d": ["The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903873", "l": "negative regulation of DNA recombinase mediator complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003176", "l": "aortic valve development", "d": ["The progression of the aortic valve over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044465", "l": "modulation of sensory perception of pain in another organism", "d": ["A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018084", "l": "peptidyl-lactic acid biosynthetic process from peptidyl-serine", "d": ["The modification of N-terminal peptidyl-serine to lactic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905143", "l": "eukaryotic translation initiation factor 2 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032384", "l": "negative 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FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035225", "l": "determination of genital disc primordium", "d": ["Allocation of embryonic cells to the genital imaginal disc founder populations. 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Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006382", "l": "adenosine to inosine editing", "d": ["The conversion of an adenosine residue to inosine in an RNA molecule by deamination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072213", "l": "metanephric capsule development", "d": ["The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. 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[{"i": "GO:0106394", "l": "negative regulation of palmitic acid catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a palmitic acid catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045903", "l": "positive regulation of translational fidelity", "d": ["Any process that increases the ability of the translational apparatus to interpret the genetic code."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019307", "l": "mannose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0042461", "l": "photoreceptor cell development", "d": ["Development of a photoreceptor, a cell that responds to 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"ic": "87.157025479615683", "identifiers": [{"i": "GO:1901420", "l": "negative regulation of response to alcohol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034379", "l": "very-low-density lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0006086", "l": "acetyl-CoA biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140645", "l": "neutrophic extracellular trap formation", "d": ["The aggregation, 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Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150023", "l": "apical dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001170", "l": "negative regulation of ATP biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046366", "l": "allose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0018377", "l": "protein myristoylation", "d": ["The covalent attachment of a myristoyl group to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044858", "l": "plasma membrane raft polarization", "d": ["The clustering and aggregation of a plasma membrane into domains. 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Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. 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This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905299", "l": "negative regulation of intestinal epithelial cell development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990010", "l": "compound eye retinal cell apoptotic process", "d": ["Any apoptotic process in a compound eye retinal cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905431", "l": "microcystin transport", "d": ["The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051492", "l": "regulation of stress fiber assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050943", "l": "negative regulation of iridophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014853", "l": "regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction", "d": ["Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). 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[{"i": "GO:1905130", "l": "carcinine import across plasma membrane", "d": ["The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0019311", "l": "sorbose metabolic process", "d": ["The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0046831", "l": "regulation of RNA export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.868222940810199", "identifiers": [{"i": "GO:0006486", "l": "protein glycosylation", "d": ["A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010116", "l": "positive regulation of abscisic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0098759", "l": "cellular response to interleukin-8", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0030587", "l": "sorocarp development", "d": ["The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. 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An example of this process is found in Dictyostelium discoideum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044518", "l": "positive regulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051796", "l": "negative regulation of timing of catagen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904853", "l": "protein localization to ascospore wall", "d": ["A process in which a protein is transported to, or maintained in, a location within an ascospore wall."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045983", "l": "positive regulation of purine nucleobase metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060163", "l": "subpallium neuron fate commitment", "d": ["The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. 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to interleukin-7", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0060135", "l": "maternal process involved in female pregnancy", "d": ["A reproductive process occurring in the mother that allows an embryo or fetus to develop within it."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0002691", "l": "regulation of cellular extravasation", "d": ["Any process that modulates the frequency, rate, or extent of cellular extravasation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0051503", "l": "adenine nucleotide transport", "d": ["The directed movement of adenine nucleotides, ATP, ADP, and/or 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Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000093", "l": "mitotic telophase", "d": ["The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009778", "l": "cyclic photosynthetic phosphorylation", "d": ["A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001713", "l": "ectodermal cell fate determination", "d": ["The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021833", "l": "cell-matrix adhesion involved in tangential migration using cell-cell interactions", "d": ["The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0043469", "l": "regulation of D-xylose catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048700", "l": "acquisition of desiccation tolerance in seed", "d": ["The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035378", "l": "carbon dioxide transmembrane transport", "d": ["The process in which carbon dioxide (CO2) is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071909", "l": "determination of stomach left/right asymmetry", "d": ["Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019618", "l": "protocatechuate catabolic process, ortho-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904873", "l": "negative regulation of telomerase RNA localization to Cajal body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902332", "l": "bacterial-type DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding that is involved in bacterial-type DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901733", "l": "quercetin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quercetin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070196", "l": "eukaryotic translation initiation factor 3 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0070503", "l": "selenium-containing prosthetic group metabolic process", "d": ["The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. 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A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048304", "l": "positive regulation of isotype switching to IgG isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0060706", "l": "cell differentiation involved in embryonic placenta development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046671", "l": "negative regulation of retinal cell programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0043316", "l": "cytotoxic T cell degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002488", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. 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The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.15940764878269", "identifiers": [{"i": "GO:0070254", "l": "mucus secretion", "d": ["The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. 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They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:1902224", "l": "ketone body metabolic process", "d": ["The chemical reactions and pathways involving ketone body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0046355", "l": "mannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034436", "l": "glycoprotein transport", "d": ["The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1902487", "l": "protein localization to non-growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035644", "l": "phosphoanandamide dephosphorylation", "d": ["The process of removing one or more phosphate groups from a phosphorylated anandamide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060946", "l": "cardiac blood vessel endothelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. 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It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0090085", "l": "regulation of protein deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein deubiquitination. 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They include the colicins, and their mechanisms of action vary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900141", "l": "regulation of oligodendrocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060531", "l": "neuroendocrine cell differentiation involved in prostate gland acinus development", "d": ["The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0044743", "l": "protein transmembrane import into intracellular organelle", "d": ["The directed movement of proteins into an intracellular organelle, across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902125", "l": "(+)-pinoresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0086091", "l": "regulation of heart rate by cardiac conduction", "d": ["A cardiac conduction process that modulates the frequency or rate of heart contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106121", "l": "positive regulation of cobalamin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905937", "l": "negative regulation of germ cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.301331245594", "identifiers": [{"i": "GO:0050957", "l": "equilibrioception", "d": ["The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. 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In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0140243", "l": "regulation of translation at synapse", "d": ["Any process that regulates translation occurring at the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033246", "l": "positive regulation of penicillin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904334", "l": "heme import across plasma membrane", "d": ["The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903385", "l": "regulation of homophilic cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of homophilic cell adhesion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904280", "l": "negative regulation of transcription by RNA polymerase V", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0008292", "l": "acetylcholine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060876", "l": "semicircular canal formation", "d": ["The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. 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It is now used as a fungicide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0040019", "l": "positive regulation of embryonic development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120196", "l": "negative regulation of anther dehiscence", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0062033", "l": "positive regulation of mitotic sister chromatid segregation", "d": ["Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0030654", "l": "beta-lactam antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.917179239854292", "identifiers": [{"i": "GO:0002200", "l": "somatic diversification of immune receptors", "d": ["The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046315", "l": "phosphocreatine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902481", "l": "gamma-tubulin complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0030168", "l": "platelet activation", "d": ["A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006267", "l": "pre-replicative complex assembly involved in nuclear cell cycle DNA replication", "d": ["The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106305", "l": "mannogen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0000409", "l": "regulation of transcription by galactose", "d": ["Any process involving galactose that modulates the frequency, rate or extent or transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061137", "l": "bud dilation", "d": ["The process in which a branch bud increases radially. 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They have a wide range of biological activities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0048884", "l": "neuromast development", "d": ["The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0035113", "l": "embryonic appendage morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903913", "l": "regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900898", "l": "positive regulation of heptadecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0072022", "l": "descending thin limb development", "d": ["The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. 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The lacrimal gland produces secretions that lubricate and protect the cornea of the eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015677", "l": "copper ion import", "d": ["The directed movement of copper ions into a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.40455714802998", "identifiers": [{"i": "GO:0030216", "l": "keratinocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001919", "l": "regulation of receptor recycling", "d": ["Any process that modulates the frequency, rate, or extent of receptor recycling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.2284025111056", "identifiers": [{"i": "GO:0051651", "l": "maintenance of location in cell", "d": ["Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070286", "l": "axonemal dynein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0045862", "l": "positive regulation of proteolysis", "d": ["Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0071376", "l": "cellular response to corticotropin-releasing hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. 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They are important components of ground substance or intercellular cement of skin and some connective tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048007", "l": "antigen processing and presentation, exogenous lipid antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. 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In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0021692", "l": "cerebellar Purkinje cell layer morphogenesis", "d": ["The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0060525", "l": "prostate glandular acinus development", "d": ["The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060690", "l": "epithelial cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018246", "l": "protein-coenzyme A linkage", "d": ["The formation of a linkage between a protein amino acid and coenzyme A."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071769", "l": "mycolate cell wall layer assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0046534", "l": "positive regulation of photoreceptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0009855", "l": "determination of bilateral symmetry", "d": ["The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000194", "l": "regulation of female gonad development", "d": ["Any process that modulates the frequency, rate or extent of female gonad development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.024411547311772", "identifiers": [{"i": "GO:1900046", "l": "regulation of hemostasis", "d": ["Any process that modulates the frequency, rate or extent of hemostasis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900672", "l": "positive regulation of F-9775A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032803", "l": "regulation of low-density lipoprotein particle receptor catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006670", "l": "sphingosine metabolic process", "d": ["The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044833", "l": "modulation by virus of host protein transport", "d": ["Any viral process that modulates the frequency, rate or extent of protein transport in its host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0043302", "l": "positive regulation of leukocyte degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010037", "l": "response to carbon dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021752", "l": "inferior salivary nucleus development", "d": ["The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0002182", "l": "cytoplasmic translational elongation", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0000266", "l": "mitochondrial fission", "d": ["The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0061323", "l": "cell proliferation involved in heart morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0014725", "l": "regulation of extraocular skeletal muscle development", "d": ["Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061456", "l": "mesenchymal stem cell migration involved in uteric bud morphogenesis", "d": ["The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0046128", "l": "purine ribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002261", "l": "mucosal lymphocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034145", "l": "positive regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0016333", "l": "morphogenesis of follicular epithelium", "d": ["The process in which the anatomical structures of a follicular epithelium are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0030038", "l": "contractile actin filament bundle assembly", "d": ["Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0009083", "l": "branched-chain amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:1902882", "l": "regulation of response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of response to oxidative stress."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000374", "l": "regulation of oxygen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of oxygen metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0120046", "l": "regulation of protein localization to medial cortical node", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0019394", "l": "glucarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:2000036", "l": "regulation of stem cell population maintenance", "d": ["Any process that modulates the frequency, rate or extent of stem cell population maintenance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905859", "l": "negative regulation of heparan sulfate proteoglycan binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0060252", "l": "positive regulation of glial cell proliferation", "d": ["Any process that activates or increases the rate or extent of glial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0043278", "l": "response to morphine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006642", "l": "triglyceride mobilization", "d": ["The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090442", "l": "trehalose catabolism in response to heat stress", "d": ["The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000750", "l": "negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900286", "l": "negative regulation of cellotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901024", "l": "4-hydroxyphenylacetate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903929", "l": "primary palate development", "d": ["The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0034505", "l": "tooth mineralization", "d": ["The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061071", "l": "urethra epithelium development", "d": ["The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1990787", "l": "negative regulation of hh target transcription factor activity", "d": ["Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033235", "l": "positive regulation of protein sumoylation", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090053", "l": "positive regulation of pericentric heterochromatin formation", "d": ["Any process that increases the frequency, rate or extent of pericentric heterochromatin formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0101026", "l": "mitotic nuclear membrane biogenesis", "d": ["A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905870", "l": "positive regulation of 3'-UTR-mediated mRNA stabilization", "d": ["Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.050016418185038", "identifiers": [{"i": "GO:1902930", "l": "regulation of alcohol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of alcohol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021568", "l": "rhombomere 2 development", "d": ["The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000928", "l": "negative regulation of cellodextrin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071335", "l": "hair follicle cell proliferation", "d": ["The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033025", "l": "regulation of mast cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of mast cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009144", "l": "purine nucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000565", "l": "negative regulation of CD8-positive, alpha-beta T cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010124", "l": "phenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylacetate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905884", "l": "negative regulation of triglyceride transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035694", "l": "mitochondrial protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021805", "l": "cell movement involved in somal translocation", "d": ["The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0106027", "l": "neuron projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000689", "l": "actomyosin contractile ring assembly actin filament organization", "d": ["An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030644", "l": "intracellular chloride ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of chloride ions within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048530", "l": "fruit morphogenesis", "d": ["The process in which the anatomical structures of a fruit are generated and organized. 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The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080141", "l": "regulation of jasmonic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0009557", "l": "antipodal cell differentiation", "d": ["The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035629", "l": "N-terminal protein amino acid N-linked glycosylation", "d": ["Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0070637", "l": "pyridine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904436", "l": "negative regulation of transferrin receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0047496", "l": "vesicle transport along microtubule", "d": ["The directed movement of a vesicle along a microtubule, mediated by motor proteins. 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"t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904737", "l": "positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046002", "l": "positive regulation of preblastoderm mitotic cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097336", "l": "response to risperidone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus."], "t": []}], 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An example of this process is found in Saccharomyces cerevisiae."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0046346", "l": "mannosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001036", "l": "negative regulation of tongue muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901844", "l": "regulation of cell communication by electrical coupling involved in cardiac conduction", "d": ["Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0090357", "l": "regulation of tryptophan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046985", "l": "positive regulation of hemoglobin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903023", "l": "regulation of ascospore-type prospore membrane formation", "d": ["Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010443", "l": "meristemoid mother cell division", "d": ["The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. 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Any cell that undergoes this type of division is a MMC."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034133", "l": "positive regulation of toll-like receptor 1 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035695", "l": "mitophagy by internal vacuole formation", "d": ["The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010925", "l": "positive regulation of inositol-polyphosphate 5-phosphatase activity", "d": ["Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080056", "l": "petal vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the petal of vascular plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0030393", "l": "fructoselysine metabolic process", "d": ["The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097298", "l": "regulation of nucleus size", "d": ["Any process that modulates the size of the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0060675", "l": "ureteric bud morphogenesis", "d": ["The process in which the ureteric bud is generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905491", "l": "positive regulation of sensory neuron axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035356", "l": "intracellular triglyceride homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of triglyceride within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0014841", "l": "skeletal muscle satellite cell proliferation", "d": ["The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1901068", "l": "guanosine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving guanosine-containing compounds (guanosines)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042122", "l": "alginic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006919", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006883", "l": "intracellular sodium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0055118", "l": "negative regulation of cardiac muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036520", "l": "astrocyte-dopaminergic neuron signaling", "d": ["Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007290", "l": "spermatid nucleus elongation", "d": ["The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045657", "l": "positive regulation of monocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048779", "l": "negative regulation of erythrophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905519", "l": "negative regulation of presynaptic active zone assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032812", "l": "positive regulation of epinephrine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019709", "l": "iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide", "d": ["The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048080", "l": "negative regulation of cuticle pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000308", "l": "negative regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0090089", "l": "regulation of dipeptide transport", "d": ["Any process that modulates the rate, frequency or extent of dipeptide transport. 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Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020033", "l": "antigenic variation", "d": ["Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.14133299147904", "identifiers": [{"i": "GO:0040007", "l": "growth", "d": ["The increase in size or mass of an entire organism, a part of an organism or a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0030224", "l": "monocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0052372", "l": "modulation by symbiont of entry into host", "d": ["Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071072", "l": "negative regulation of phospholipid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0098780", "l": "response to mitochondrial depolarisation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0033374", "l": "protein localization to T cell secretory granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0032496", "l": "response to lipopolysaccharide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002569", "l": "somatic diversification of immune receptors by N region addition", "d": ["The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. 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The process ends when the structural rudiment is recognizable."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060045", "l": "positive regulation of cardiac muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.534762107606241", "identifiers": [{"i": "GO:0042310", "l": "vasoconstriction", "d": ["A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2001091", "l": "nigerotriose transport", "d": ["The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045795", "l": "positive regulation of cell volume", "d": ["Any process that increases cell volume."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0051101", "l": "regulation of DNA binding", "d": ["Any process that modulates the frequency, rate or extent of DNA binding. 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The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060530", "l": "smooth muscle cell differentiation involved in prostate glandular acinus development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043032", "l": "positive regulation of macrophage activation", "d": ["Any process that stimulates, induces or increases the rate of macrophage activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045887", "l": "positive regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0045687", "l": "positive regulation of glial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of glia cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990264", "l": "peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity", "d": ["Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903542", "l": "negative regulation of exosomal secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0006449", "l": "regulation of translational termination", "d": ["Any process that modulates the frequency, rate or extent of translational termination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061074", "l": "regulation of neural retina development", "d": ["Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. 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This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0010043", "l": "response to zinc ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.929890650779797", "identifiers": [{"i": "GO:0050808", "l": "synapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061284", "l": "specification of mesonephric proximal tubule identity", "d": ["The process in which the proximal tubule of the mesonephric nephron acquires its identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0000966", "l": "RNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an RNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.674339030385639", "identifiers": [{"i": "GO:0040017", "l": "positive regulation of locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0002371", "l": "dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a dendritic cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061436", "l": "establishment of skin barrier", "d": ["Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0018217", "l": "peptidyl-aspartic acid phosphorylation", "d": ["The phosphorylation of peptidyl-aspartic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:1901184", "l": "regulation of ERBB signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ERBB signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010105", "l": "negative regulation of ethylene-activated signaling pathway", "d": ["Any process that stops or prevents ethylene (ethene) signal transduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097315", "l": "response to N-acetyl-D-glucosamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:1903307", "l": "positive regulation of regulated secretory pathway", "d": ["Any process that activates or increases the frequency, rate or extent of regulated secretory pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905443", "l": "regulation of clathrin coat assembly", "d": ["Any process that modulates the frequency, rate or extent of clathrin coat assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902635", "l": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0032782", "l": "bile acid secretion", "d": ["The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010957", "l": "negative regulation of vitamin D biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. 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"identifiers": [{"i": "GO:1900396", "l": "positive regulation of kojic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "49.732655555095533", "identifiers": [{"i": "GO:0051938", "l": "L-glutamate import", "d": ["The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090363", "l": "regulation of proteasome core complex assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0097067", "l": "cellular response to thyroid hormone stimulus", "d": ["A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.232224033214663", "identifiers": [{"i": "GO:0003333", "l": "amino acid transmembrane transport", "d": ["The process in which an amino acid is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901121", "l": "tobramycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tobramycin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.024897738786478", "identifiers": [{"i": "GO:0002883", "l": "regulation of hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of hypersensitivity."], "t": []}], "taxa": 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both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1900614", "l": "F-9775B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of F-9775B."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035810", "l": "positive regulation of urine volume", "d": ["Any process that increases the amount of urine excreted from the body over a unit of time."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032648", "l": "regulation of interferon-beta production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-beta production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0001787", "l": "natural killer cell proliferation", "d": ["The expansion of a natural killer cell population by cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903519", "l": "regulation of mammary gland involution", "d": ["Any process that modulates the frequency, rate or extent of mammary gland involution."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007121", "l": "bipolar cellular bud site selection", "d": ["The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:1905048", "l": "regulation of metallopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of metallopeptidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.723777338832122", "identifiers": [{"i": "GO:0046890", "l": "regulation of lipid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045772", "l": "positive regulation of autophagosome size", "d": ["Any process that increases autophagosome size."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110163", "l": "negative regulation of mitotic spindle elongation (spindle phase three)", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003340", "l": "negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002101", "l": "tRNA wobble cytosine modification", "d": ["The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.944488487207011", "identifiers": [{"i": "GO:0001508", "l": "action 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The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. 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cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072382", "l": "minus-end-directed vesicle transport along microtubule", "d": ["The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901112", "l": "actinorhodin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of actinorhodin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060929", "l": "atrioventricular node cell fate commitment", "d": ["The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0042398", "l": "cellular modified amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904447", "l": "folate import across plasma membrane", "d": ["The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904092", "l": "regulation of autophagic cell death", "d": ["Any process that modulates the frequency, rate or extent of autophagic cell death."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905459", "l": "regulation of vascular associated smooth muscle cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061380", "l": "superior colliculus development", "d": ["The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.490486312819655", "identifiers": [{"i": "GO:0009313", "l": "oligosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.857458315248223", "identifiers": [{"i": "GO:0070887", "l": "cellular response to chemical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010069", "l": "zygote asymmetric cytokinesis in embryo sac", "d": ["The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0002808", "l": "regulation of antibacterial peptide biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0018201", "l": "peptidyl-glycine modification", "d": ["The modification of peptidyl-glycine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080183", "l": "response to photooxidative stress", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903840", "l": "response to arsenite(3-)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021834", "l": "chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration", "d": ["The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140367", "l": "antibacterial innate immune response", "d": ["An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042892", "l": "chloramphenicol transmembrane transport", "d": ["The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019524", "l": "keto-D-gluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0035434", "l": "copper ion transmembrane transport", "d": ["The directed movement of copper cation across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002650", "l": "negative regulation of tolerance induction to self antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042370", "l": "thiamine diphosphate dephosphorylation", "d": ["The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904070", "l": "ascaroside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ascaroside."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0075528", "l": "perturbation by virus of host immune response", "d": ["A process in which a virus effects a change in the host immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009693", "l": "ethylene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901078", "l": "negative regulation of relaxation of muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.504650478785891", "identifiers": [{"i": "GO:0000375", "l": "RNA splicing, via transesterification reactions", "d": ["Splicing of RNA via a series of two transesterification reactions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002731", "l": "negative regulation of dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0019694", "l": "alkanesulfonate metabolic process", "d": ["The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001186", "l": "negative regulation of CD8-positive, alpha-beta T cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044727", "l": "epigenetic programing of male pronucleus", "d": ["The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032920", "l": "putrescine acetylation", "d": ["The modification of putrescine by addition of acetyl groups."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901466", "l": "regulation of ferulate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ferulate catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.322133444801921", "identifiers": [{"i": "GO:0001503", "l": "ossification", "d": ["The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060385", "l": "axonogenesis involved in innervation", "d": ["The neurite development process that generates a long process of a neuron, as it invades a target tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048684", "l": "positive regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072117", "l": "head kidney formation", "d": ["The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120317", "l": "sperm mitochondrial sheath assembly", "d": ["The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:1903909", "l": "regulation of receptor clustering", "d": ["Any process that modulates the frequency, rate or extent of receptor clustering."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060556", "l": "regulation of vitamin D biosynthetic process", "d": ["Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0003380", "l": "establishment or maintenance of cytoskeleton polarity involved in gastrulation", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070185", "l": "mitochondrial valyl-tRNA aminoacylation", "d": ["The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903588", "l": "negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0019095", "l": "pole plasm mitochondrial rRNA localization", "d": ["Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018882", "l": "(+)-camphor metabolic process", "d": ["The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900451", "l": "positive regulation of glutamate receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904919", "l": "transmembrane L-cystine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990690", "l": "Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0072538", "l": "T-helper 17 type immune response", "d": ["An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900509", "l": "regulation of pentose catabolic process to ethanol", "d": ["Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071766", "l": "Actinobacterium-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001263", "l": "regulation of C-C chemokine binding", "d": ["Any process that modulates the frequency, rate or extent of C-C chemokine binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051110", "l": "peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine", "d": ["The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039704", "l": "viral translational shunt", "d": ["A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010477", "l": "response to sulfur dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "44.9421124326526", "identifiers": [{"i": "GO:0034220", "l": "monoatomic ion transmembrane transport", "d": ["A process in which a monoatomic ion is transported across a membrane. 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Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0031641", "l": "regulation of myelination", "d": ["Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0007398", "l": "ectoderm development", "d": ["The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010757", "l": "negative regulation of plasminogen activation", "d": ["Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000225", "l": "negative regulation of testosterone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0050858", "l": "negative regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1901539", "l": "ent-pimara-8(14),15-diene metabolic process", "d": ["The chemical reactions and pathways involving ent-pimara-8(14),15-diene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045579", "l": "positive regulation of B cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of B cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048826", "l": "cotyledon morphogenesis", "d": ["The process in which the anatomical structures of the cotyledon are generated and organized. 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The cotyledons may appear above ground and show photosynthetic activity in the seedling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900997", "l": "benzene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070755", "l": "negative regulation of interleukin-35 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071839", "l": "apoptotic process in bone marrow cell", "d": ["The apoptotic process in cells in the bone marrow."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021647", "l": "vestibulocochlear nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901365", "l": "funalenone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of funalenone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046330", "l": "positive regulation of JNK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0061245", "l": "establishment or maintenance of bipolar cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048801", "l": "antennal joint morphogenesis", "d": ["The process in which the anatomical structures of the antennal joint are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0051189", "l": "prosthetic group metabolic process", "d": ["The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0075197", "l": "haustorium neck formation", "d": ["The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903316", "l": "positive regulation of nitrogen cycle metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036271", "l": "response to methylphenidate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0032537", "l": "host-seeking behavior", "d": ["The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904461", "l": "ergosteryl 3-beta-D-glucoside metabolic process", "d": ["The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905440", "l": "cellular response to chondroitin 6'-sulfate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030466", "l": "silent mating-type cassette heterochromatin formation", "d": ["Repression of transcription at silent mating-type loci by alteration of the structure of chromatin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009223", "l": "pyrimidine deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061356", "l": "regulation of Wnt protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0000479", "l": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. 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In a two-pass circulatory system blood passes twice through the heart to supply the body once."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075265", "l": "positive regulation of oogonium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000124", "l": "regulation of endocannabinoid signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902626", "l": "assembly of large subunit precursor of preribosome", "d": ["The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0045342", "l": "MHC class II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900199", "l": "positive regulation of protein export from nucleus during meiotic anaphase II", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0072498", "l": "embryonic skeletal joint development", "d": ["The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0034656", "l": "nucleobase-containing small molecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051295", "l": "establishment of meiotic spindle localization", "d": ["The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140113", "l": "extracellular microvesicle biogenesis", "d": ["The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001768", "l": "establishment of T cell polarity", "d": ["The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0061303", "l": "cornea development in camera-type eye", "d": ["The progression of the cornea over time, from its formation to the mature structure. 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At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904325", "l": "positive regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.806983861220772", "identifiers": [{"i": "GO:0006402", "l": "mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0032814", "l": "regulation of natural killer cell activation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0052779", "l": "amino disaccharide metabolic process", "d": ["The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000633", "l": "positive regulation of pre-miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of pre-microRNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0043405", "l": "regulation of MAP kinase activity", "d": ["Any process that modulates the frequency, rate or extent of MAP kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048685", "l": "negative regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901175", "l": "lycopene metabolic process", "d": ["The chemical reactions and pathways involving lycopene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.914756808362391", "identifiers": [{"i": "GO:0006091", "l": "generation of precursor metabolites and energy", "d": ["The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060088", "l": "auditory receptor cell stereocilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. 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The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006971", "l": "hypotonic response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051511", "l": "negative regulation of unidimensional cell growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034161", "l": "positive regulation of toll-like receptor 8 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905364", "l": "regulation of endosomal vesicle fusion", "d": ["Any process that modulates the frequency, rate or extent of endosomal vesicle fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061549", "l": "sympathetic ganglion development", "d": ["The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903229", "l": "xanthosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xanthosine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0044521", "l": "envenomation resulting in muscle damage in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.566751859216453", "identifiers": [{"i": "GO:0006221", "l": "pyrimidine nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904227", "l": "negative regulation of glycogen synthase activity, transferring glucose-1-phosphate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032913", "l": "negative regulation of transforming growth factor beta3 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140125", "l": "thiamine import across plasma membrane", "d": ["The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905787", "l": "regulation of detection of mechanical stimulus involved in sensory perception of touch", "d": ["Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0046552", "l": "photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. 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This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0009089", "l": "lysine biosynthetic process via diaminopimelate", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0061454", "l": "release of sequestered calcium ion into cytosol by Golgi", "d": ["The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048860", "l": "glioblast division", "d": ["The process resulting in the physical partitioning and separation of a glioblast into daughter cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046626", "l": "regulation of insulin receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of insulin receptor signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.866383925293761", "identifiers": [{"i": "GO:0060759", "l": "regulation of response to cytokine stimulus", "d": ["Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090364", "l": "regulation of proteasome assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0032240", "l": "negative regulation of nucleobase-containing compound transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060101", "l": "negative regulation of phagocytosis, engulfment", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000535", "l": "regulation of entry of bacterium into host cell", "d": ["Any process that modulates the frequency, rate or extent of entry of bacterium into host cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903575", "l": "cornified envelope assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a cornified envelope."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000065", "l": "negative regulation of cortisol biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050992", "l": "dimethylallyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000918", "l": "division septum site selection", "d": ["The process of marking the site where a division septum will form."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0010909", "l": "positive regulation of heparan sulfate proteoglycan biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. 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The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071373", "l": "cellular response to luteinizing hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0015728", "l": "mevalonate transport", "d": ["The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.756196854933549", "identifiers": [{"i": "GO:0006417", "l": "regulation of translation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:1904304", "l": "regulation of gastro-intestinal system smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0098883", "l": "synapse pruning", "d": ["A cellular process that results in the controlled breakdown of synapse. 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033548", "l": "myo-inositol hexakisphosphate biosynthetic process, lipid-independent", "d": ["The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1901673", "l": "regulation of mitotic spindle assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic spindle assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901914", "l": "negative regulation of capsule organization", "d": ["Any process that stops, prevents or reduces the 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Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904118", "l": "regulation of otic vesicle morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0071218", "l": "cellular response to misfolded protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010739", "l": "positive regulation of protein kinase A signaling", "d": ["Any process that increases the rate, frequency, or extent of protein kinase A signaling. 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This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060455", "l": "negative regulation of gastric acid secretion", "d": ["Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0015712", "l": "hexose phosphate transport", "d": ["The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:1904746", "l": "negative regulation of apoptotic process involved in development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044351", "l": "macropinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001009", "l": "regulation of plant-type cell wall cellulose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0044539", "l": "long-chain fatty acid import into cell", "d": ["The directed movement of a long-chain fatty acid from outside of a cell into a cell. 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A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.683527111924249", "identifiers": [{"i": "GO:0048820", "l": "hair follicle maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001809", "l": "positive regulation of type IV hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0048915", "l": "posterior lateral line system development", "d": ["The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. 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The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0016925", "l": "protein sumoylation", "d": ["The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901595", "l": "response to hesperadin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900508", "l": "positive regulation of iron-sulfur-molybdenum cofactor assembly", "d": ["Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.584902930324013", "identifiers": [{"i": "GO:0071626", "l": "mastication", "d": ["The process of biting and mashing food with the teeth prior to swallowing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990110", "l": "callus formation", "d": ["The process by which a callus is formed at a wound site. 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Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0007638", "l": "mechanosensory behavior", "d": ["Behavior that is dependent upon the sensation of a mechanical stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045967", "l": "negative regulation of growth rate", "d": ["Any process that reduces the rate of growth of all or part of an organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019836", "l": "hemolysis by symbiont of host erythrocytes", "d": ["The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072092", "l": "ureteric bud invasion", "d": ["The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903226", "l": "positive regulation of endodermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018923", "l": "limonene metabolic process", "d": ["The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0002407", "l": "dendritic cell chemotaxis", "d": ["The movement of a dendritic cell in response to an external stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0097212", "l": "lysosomal membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0045575", "l": "basophil activation", "d": ["The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1902724", "l": "positive regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904195", "l": "regulation of granulosa cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of granulosa cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.247531668414297", "identifiers": [{"i": "GO:0046635", "l": "positive regulation of alpha-beta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006290", "l": "pyrimidine dimer repair", "d": ["The repair of UV-induced T-T, C-T and C-C dimers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0032634", "l": "interleukin-5 production", "d": ["The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0060143", "l": "positive regulation 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"ic": "100", "identifiers": [{"i": "GO:0042683", "l": "negative regulation of compound eye cone cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031121", "l": "equatorial microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060635", "l": "positive regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0061439", "l": "kidney vasculature morphogenesis", "d": ["The process in which the kidney vasculature is generated and organized. 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Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110155", "l": "NAD-cap decapping", "d": ["Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902185", "l": "positive regulation of shoot apical meristem development", "d": ["Any process that activates or increases the frequency, rate or extent of shoot apical meristem development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:2000031", "l": "regulation of salicylic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0060117", "l": "auditory receptor cell development", "d": ["The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. 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Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904846", "l": "negative regulation of establishment of bipolar cell polarity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032728", "l": "positive regulation of interferon-beta production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-beta production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0075328", "l": "formation of arbuscule for nutrient acquisition", "d": ["The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. 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The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032717", "l": "negative regulation of interleukin-8 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106034", "l": "protein maturation by [2Fe-2S] cluster transfer", "d": ["The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905637", "l": "regulation of mitochondrial mRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0001698", "l": "gastrin-induced gastric acid secretion", "d": ["The regulated release of gastric acid induced by the interaction of gastrin with its receptor."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036277", "l": "response to anticonvulsant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0075262", "l": "negative regulation of spore-bearing organ development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905945", "l": "regulation of response to calcium ion", "d": ["Any process that modulates the frequency, rate or extent of response to calcium ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035441", "l": "cell migration involved in vasculogenesis", "d": ["The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0006434", "l": "seryl-tRNA aminoacylation", "d": ["The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021504", "l": "neural fold hinge point formation", "d": ["The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. 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This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901624", "l": "negative regulation of lymphocyte chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0032946", "l": "positive regulation of mononuclear cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035212", "l": "cell competition in a multicellular organism", "d": ["Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150138", "l": "negative regulation of interleukin-37 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0032365", "l": "intracellular lipid transport", "d": ["The directed movement of lipids within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.625268296404869", "identifiers": [{"i": "GO:0010970", "l": "transport along microtubule", "d": ["The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001194", "l": "regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000038", "l": "regulation of stomatal complex development", "d": ["Any process that modulates the frequency, rate or extent of stomatal complex development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0090317", "l": "negative regulation of intracellular protein transport", "d": ["Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0042273", "l": "ribosomal large subunit biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075511", "l": "macropinosome lysis involved in viral entry into host cell", "d": ["Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. 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wing size", "d": ["Any process that increases the size of an imaginal disc-derived wing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.336726978210059", "identifiers": [{"i": "GO:0018130", "l": "heterocycle biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900661", "l": "regulation of emericellamide A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0032635", "l": "interleukin-6 production", "d": ["The appearance of interleukin-6 due to biosynthesis or secretion following a cellular 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frequency, rate or extent of plasma cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0018211", "l": "peptidyl-tryptophan modification", "d": ["The chemical alteration of a tryptophan residue in a peptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034420", "l": "co-translational protein acetylation", "d": ["The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0070472", "l": "regulation of uterine smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1903692", "l": "methionine import across plasma membrane", "d": ["The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901814", "l": "astaxanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of astaxanthin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901760", "l": "beta-L-Ara4N-lipid A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052067", "l": "disruption of host phagocytosis", "d": ["A process in which in a symbiont interferes with or inhibits host phagocytosis by targeting phagocytic signaling or the cellular phagocytic machinery. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:2000736", "l": "regulation of stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of stem cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070360", "l": "actin polymerization-dependent cell-to-cell migration in host", "d": ["The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration from cell to cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120292", "l": "positive regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0032108", "l": "negative regulation of response to nutrient levels", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046694", "l": "sperm incapacitation", "d": ["The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032088", "l": "negative regulation of NF-kappaB transcription factor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021768", "l": "nucleus accumbens development", "d": ["The progression of the nucleus accumbens over time from its initial formation until its mature state. 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K6-linked ubiquitination is involved in DNA repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110062", "l": "negative regulation of angiotensin-activated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071461", "l": "cellular response to redox state", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0042701", "l": "progesterone secretion", "d": ["The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903527", "l": "positive regulation of membrane tubulation", "d": ["Any process that activates or increases the frequency, rate or extent of membrane tubulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0055021", "l": "regulation of cardiac muscle tissue growth", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904803", "l": "regulation of translation involved in cellular response to UV", "d": ["Any regulation of translation that is involved in cellular response to UV."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009258", "l": "10-formyltetrahydrofolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0061537", "l": "glycine secretion, neurotransmission", "d": ["The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048906", "l": "anterior lateral line neuromast support cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090211", "l": "positive regulation of establishment of blood-brain barrier", "d": ["Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0075120", "l": "symbiont-mediated suppression of host G protein-coupled receptor signal transduction", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a G protein-coupled receptor signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035984", "l": "cellular response to trichostatin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0140448", "l": "signaling receptor ligand precursor processing", "d": ["The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000913", "l": "preprophase band assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0099171", "l": "presynaptic modulation of chemical synaptic transmission", "d": ["Any process, acting in the presynapse that results in modulation of chemical synaptic transmission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0030282", "l": "bone mineralization", "d": ["The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048297", "l": "negative regulation of isotype switching to IgA isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110102", "l": "ribulose bisphosphate carboxylase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.088320895280148", "identifiers": [{"i": "GO:0071675", "l": "regulation of mononuclear cell migration", "d": ["Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120137", "l": "positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity", "d": ["Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903997", "l": "positive regulation of non-membrane spanning protein tyrosine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036298", "l": "recombinational interstrand cross-link repair", "d": ["Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1904519", "l": "protein localization to microtubule minus-end", "d": ["A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0002021", "l": "response to dietary excess", "d": ["The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904702", "l": "regulation of protein localization to adherens junction", "d": ["Any process that modulates the frequency, rate or extent of protein localization to adherens junction. 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This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106147", "l": "fraxetin biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation of fraxetin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0032671", "l": "regulation of interleukin-27 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-27 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0018094", "l": "protein polyglycylation", "d": ["The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042682", "l": "regulation of compound eye cone cell fate specification", "d": ["Any process that mediates the specification of a cell into a compound eye cone cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060325", "l": "face morphogenesis", "d": ["The process in which the anatomical structures of the face are generated and organized. 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The zygospore forms between them and then breaks away."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905723", "l": "negative regulation of trypanothione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035037", "l": "sperm entry", "d": ["An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900003", "l": "regulation of serine-type endopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075315", "l": "positive regulation of basidium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0030042", "l": "actin filament depolymerization", "d": ["Disassembly of actin filaments by the removal of actin monomers from a filament."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0017121", "l": "plasma membrane phospholipid scrambling", "d": ["The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1904862", "l": "inhibitory synapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900801", "l": "cspyrone B1 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cspyrone B1."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0097343", "l": "ripoptosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046153", "l": "ommochrome catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045942", "l": "negative regulation of phosphorus utilization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.626384042261094", "identifiers": [{"i": "GO:0002699", "l": "positive regulation of immune effector process", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune effector process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042858", "l": "chrysobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900703", "l": "positive regulation of orcinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050496", "l": "peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine", "d": ["The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1990891", "l": "mitotic sister chromatid arm separation", "d": ["The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900936", "l": "negative regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010425", "l": "DNA methylation on cytosine within a CNG sequence", "d": ["The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900845", "l": "positive regulation of monodictyphenone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000070", "l": "regulation of response to water deprivation", "d": ["Any process that modulates the frequency, rate or extent of response to water deprivation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140763", "l": "programmed DNA elimination by elimination of internal DNA segments", "d": ["A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903445", "l": "protein transport from ciliary membrane to plasma membrane", "d": ["The directed movement of protein from ciliary membrane to plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032716", "l": "negative regulation of interleukin-7 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0048508", "l": "embryonic meristem development", "d": ["The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0022018", "l": "lateral ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043314", "l": "negative regulation of neutrophil degranulation", "d": ["Any process that stops, prevents, or reduces the rate of neutrophil degranulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.672771840408203", "identifiers": [{"i": "GO:0016197", "l": "endosomal transport", "d": ["The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045804", "l": "negative regulation of eclosion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019445", "l": "tyrosine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120066", "l": "pyloric canal smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051519", "l": "activation of bipolar cell growth", "d": ["Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.58909006025462", "identifiers": [{"i": "GO:0060271", "l": "cilium assembly", "d": ["The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. 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The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060504", "l": "positive regulation of epithelial cell proliferation involved in lung bud dilation", "d": ["Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.617478300466217", "identifiers": [{"i": "GO:0007626", "l": "locomotory behavior", "d": ["The specific movement from place to place of an organism in response to external or internal stimuli. 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"identifiers": [{"i": "GO:0043267", "l": "negative regulation of potassium ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002044", "l": "blood vessel endothelial cell migration involved in intussusceptive angiogenesis", "d": ["The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900700", "l": "positive regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.496617203483822", "identifiers": [{"i": "GO:0043403", "l": "skeletal muscle tissue regeneration", "d": ["The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0032775", "l": "DNA methylation on adenine", "d": ["The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1902198", "l": "3-methylbut-2-enoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905746", "l": "positive regulation of mRNA cis splicing, via spliceosome", "d": ["Any process that activates or 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0003175", "l": "tricuspid valve development", "d": ["The progression of the tricuspid valve over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001286", "l": "regulation of caveolin-mediated endocytosis", "d": ["Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080001", "l": "mucilage extrusion from seed coat", "d": ["The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. 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It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.655379925225219", "identifiers": [{"i": "GO:0002228", "l": "natural killer cell mediated immunity", "d": ["The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000334", "l": "positive regulation of blood microparticle formation", "d": ["Any process that activates or increases the frequency, rate or extent of blood microparticle formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015829", "l": "valine transport", "d": ["The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0033688", "l": "regulation of osteoblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of osteoblast proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000205", "l": "positive regulation of ribosomal large subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072094", "l": "metanephric renal vesicle induction", "d": ["Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045712", "l": "positive regulation of larval salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.505374077738324", "identifiers": [{"i": "GO:0007605", "l": "sensory perception of sound", "d": ["The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. 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Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048785", "l": "hatching gland development", "d": ["The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. 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Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046007", "l": "negative regulation of activated T cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0014056", "l": "regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2000634", "l": "regulation of primary miRNA processing", "d": ["Any process that modulates the frequency, rate or extent of primary microRNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1902916", "l": "positive regulation of protein polyubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein polyubiquitination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140247", "l": "protein catabolic process at presynapse", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120315", "l": "positive regulation of oocyte karyosome formation", "d": ["Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030204", "l": "chondroitin sulfate metabolic process", "d": ["The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. 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This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0150119", "l": "negative regulation of protein localization to cell-cell junction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.886036779686677", "identifiers": [{"i": "GO:0006914", "l": "autophagy", "d": ["The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. 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The pentenyl ring may carry other substituents."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048058", "l": "compound eye corneal lens development", "d": ["The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.176141984063477", "identifiers": [{"i": "GO:0032388", "l": "positive regulation of intracellular transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045200", "l": "establishment of neuroblast polarity", "d": ["The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033382", "l": "maintenance of granzyme B location in T cell secretory granule", "d": ["A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0017015", "l": "regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001148", "l": "regulation of dipeptide transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010095", "l": "specification of petal identity", "d": ["The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990627", "l": "mitochondrial inner membrane fusion", "d": ["The membrane organization process that joins two mitochondrial inner membranes to form a single membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035627", "l": "ceramide transport", "d": ["The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0010526", "l": "retrotransposon silencing", "d": ["Any process that decreases the frequency, rate or extent of retrotransposition. 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"identifiers": [{"i": "GO:0018357", "l": "protein-phycourobilin linkage via phycourobilin-bis-L-cysteine", "d": ["The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0036296", "l": "response to increased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903419", "l": "protein localization to cortical endoplasmic reticulum", "d": ["A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": 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"identifiers": [{"i": "GO:2000490", "l": "negative regulation of hepatic stellate cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072308", "l": "negative regulation of metanephric nephron tubule epithelial cell differentiation", "d": ["Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070593", "l": "dendrite self-avoidance", "d": ["The process in which dendrites recognize and avoid contact with sister dendrites from the same cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0090277", "l": "positive regulation of peptide hormone secretion", "d": ["Any 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Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0048806", "l": "genitalia development", "d": ["The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048506", "l": "regulation of timing of meristematic phase transition", "d": ["Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021672", "l": "rhombomere 7 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 7. 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The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010084", "l": "specification of animal organ axis polarity", "d": ["The process in which the polarity of an animal organ axis is specified."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000220", "l": "regulation of pseudohyphal growth", "d": ["Any process that modulates the frequency, rate or extent of pseudohyphal growth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0043406", "l": "positive regulation of MAP kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of MAP kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "53.417991359128813", "identifiers": [{"i": "GO:0043933", "l": "protein-containing complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0002911", "l": "regulation of lymphocyte anergy", "d": ["Any process that modulates the frequency, rate, or extent of lymphocyte anergy."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072649", "l": "interferon-kappa production", "d": ["The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0052799", "l": "coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. 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These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060870", "l": "cell wall disassembly involved in floral organ abscission", "d": ["A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120311", "l": "ciliary pro-basal body maturation", "d": ["A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.007505823603481", "identifiers": [{"i": "GO:0002418", "l": "immune response to tumor cell", "d": ["An immune system process that functions in the response of an organism to a tumor cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045792", "l": "negative regulation of cell size", "d": ["Any process that reduces cell size."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.080620097219125", "identifiers": [{"i": "GO:0010927", "l": "cellular component assembly involved in morphogenesis", "d": ["The cellular component assembly that is part of the initial shaping of the component during its developmental progression."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.449113659480474", "identifiers": [{"i": "GO:0060173", "l": "limb development", "d": ["The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. 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Examples include legs, arms or some types of fin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001288", "l": "positive regulation of caveolin-mediated endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033616", "l": "plasma membrane proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0170043", "l": "non-proteinogenic amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045725", "l": "positive regulation of glycogen biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003238", "l": "conus arteriosus development", "d": ["The progression of the conus arteriosus over time, from its formation to the mature structure. 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The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. 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The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061321", "l": "garland nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097338", "l": "response to clozapine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0098511", "l": "sensory perception of low humidity", "d": ["The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. 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The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902512", "l": "positive regulation of apoptotic DNA fragmentation", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.335741739186091", "identifiers": [{"i": "GO:0000725", "l": "recombinational repair", "d": ["A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019508", "l": "2,5-dihydroxypyridine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000429", "l": "negative regulation of neutrophil aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021905", "l": "forebrain-midbrain boundary formation", "d": ["The process whose specific outcome is the creation of the forebrain-midbrain boundary."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045071", "l": "negative regulation of viral genome replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900947", "l": "regulation of isoprene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of isoprene biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:2000892", "l": "cellobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellobiose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:0006641", "l": "triglyceride metabolic process", "d": ["The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045220", "l": "positive regulation of FasL production", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140591", "l": "nuclear envelope budding", "d": ["The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. 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For example, the migration of cells from the surface to the interior of the embryo (ingression)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061034", "l": "olfactory bulb mitral cell layer development", "d": ["The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. 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The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042669", "l": "regulation of inner ear auditory receptor cell fate specification", "d": ["Any process that mediates the specification of a cell into an auditory hair cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.59917137531788", "identifiers": [{"i": "GO:0140962", "l": "multicellular organismal-level chemical homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901746", "l": "prephenate(2-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prephenate(2-)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002599", "l": "negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0048293", "l": "regulation of isotype switching to IgE isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016348", "l": "imaginal disc-derived leg joint morphogenesis", "d": ["The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. 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In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0034175", "l": "regulation of toll-like receptor 12 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:1901335", "l": "lactone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044761", "l": "negative regulation by symbiont of host cholinergic synaptic transmission", "d": ["Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902380", "l": "positive regulation of endoribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of endoribonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006064", "l": "glucuronate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.820554254294692", "identifiers": [{"i": "GO:0006940", "l": "regulation of smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042930", "l": "enterobactin transport", "d": ["The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0009148", "l": "pyrimidine nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903469", "l": "removal of RNA primer involved in mitotic DNA replication", "d": ["Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042150", "l": "plasmid recombination", "d": ["A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0019433", "l": "triglyceride catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035542", "l": "regulation of SNARE complex assembly", "d": ["Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905072", "l": "cardiac jelly development", "d": ["The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:1905709", "l": "negative regulation of membrane permeability", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020014", "l": "schizogony", "d": ["Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.084918961990851", "identifiers": [{"i": "GO:0007620", "l": "copulation", "d": ["The act of sexual union between male and female, involving the transfer of sperm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903303", "l": "negative regulation of pyruvate kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032901", "l": "positive regulation of neurotrophin production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.249098858391747", "identifiers": [{"i": "GO:0007052", "l": "mitotic spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903546", "l": "protein localization to photoreceptor outer segment", "d": ["A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048724", "l": "epistomal sclerite development", "d": ["The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035079", "l": "polytene chromosome puffing", "d": ["The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0099563", "l": "modification of synaptic structure", "d": ["Any process that modifies the structure/morphology of a synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090160", "l": "Golgi to lysosome transport", "d": ["The directed movement of substances from the Golgi to lysosomes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034975", "l": "protein folding in endoplasmic reticulum", "d": ["A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006273", "l": "lagging strand elongation", "d": ["The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061843", "l": "Sertoli cell barrier remodeling", "d": ["The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072054", "l": "renal outer medulla development", "d": ["The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904153", "l": "negative regulation of retrograde protein transport, ER to cytosol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0010264", "l": "myo-inositol hexakisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0051280", "l": "negative regulation of release of sequestered calcium ion into cytosol", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000916", "l": "negative regulation of glucuronoxylan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0048559", "l": "establishment of floral organ orientation", "d": ["The process that determines the orientation of the floral organs with reference to the central axis of the flower."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001144", "l": "regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033571", "l": "lactoferrin transport", "d": ["The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042666", "l": "negative regulation of ectodermal cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0009228", "l": "thiamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006229", "l": "dUTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0035179", "l": "larval turning behavior", "d": ["Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1990636", "l": "reproductive senescence", "d": ["A life cycle stage during which the reproductive capacity and fitness of an organism declines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039708", "l": "nuclear capsid assembly", "d": ["The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046946", "l": "hydroxylysine metabolic process", "d": ["The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009183", "l": "purine deoxyribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0045881", "l": "positive regulation of sporulation resulting in formation of a cellular spore", "d": ["Any process that activates or increases the frequency, rate or extent of sporulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000714", "l": "meiotic strand displacement", "d": ["The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0000462", "l": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900156", "l": "positive regulation of bone trabecula formation", "d": ["Any process that activates or increases the frequency, rate or extent of bone trabecula formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.180713427975022", "identifiers": [{"i": "GO:0014831", "l": "gastro-intestinal system smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0099555", "l": "trans-synaptic signaling by nitric oxide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000274", "l": "regulation of epithelial cell migration, open tracheal system", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0009804", "l": "coumarin metabolic process", "d": ["The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072217", "l": "negative regulation of metanephros development", "d": ["Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009849", "l": "tryptophan-independent indoleacetic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902783", "l": "cellular response to decane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0042660", "l": "positive regulation of cell fate specification", "d": ["Any process that activates or enables a cell to adopt a specific fate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901296", "l": "negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905757", "l": "negative regulation of primary cell septum biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052864", "l": "1-deoxy-D-xylulose 5-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0044826", "l": "viral genome integration into host DNA", "d": ["The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0097039", "l": "protein linear polyubiquitination", "d": ["A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0009259", "l": "ribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0051409", "l": "response to nitrosative stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. 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The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.923108426128749", "identifiers": [{"i": "GO:0071709", "l": "membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0071450", "l": "cellular response to oxygen radical", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. 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The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1900983", "l": "vindoline metabolic process", "d": ["The chemical reactions and pathways involving vindoline."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035164", "l": "embryonic plasmatocyte differentiation", "d": ["The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0021695", "l": "cerebellar cortex development", "d": ["The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014915", "l": "regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0061181", "l": "regulation of chondrocyte development", "d": ["Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:1990772", "l": "substance P secretion", "d": ["The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900722", "l": "regulation of protein adenylylation", "d": ["Any process that modulates the frequency, rate or extent of protein adenylylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0036344", "l": "platelet morphogenesis", "d": ["Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033603", "l": "positive regulation of dopamine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046171", "l": "octanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021649", "l": "vestibulocochlear nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905432", "l": "regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046520", "l": "sphingoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0046292", "l": "formaldehyde metabolic process", "d": ["The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.845451993081149", "identifiers": [{"i": "GO:0001775", "l": "cell activation", "d": ["A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0006106", "l": "fumarate metabolic process", "d": ["The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072232", "l": "metanephric proximal convoluted tubule segment 2 development", "d": ["The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061728", "l": "GDP-mannose biosynthetic process from mannose", "d": ["The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072154", "l": "proximal convoluted tubule segment 1 cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1905371", "l": "ceramide phosphoethanolamine metabolic process", "d": ["The chemical reactions and pathways involving ceramide phosphoethanolamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0052314", "l": "phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030715", "l": "oocyte growth in germarium-derived egg chamber", "d": ["The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0072243", "l": "metanephric nephron epithelium development", "d": ["The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035146", "l": "tube fusion", "d": ["The joining of specific branches of a tubular system to form a continuous network."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035508", "l": "positive regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030631", "l": "pyrrolysine incorporation", "d": ["The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0035017", "l": "cuticle pattern formation", "d": ["The regionalization process that gives rise to the patterns of cell differentiation in the cuticle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0045920", "l": "negative regulation of exocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061970", "l": "maintenance of right sidedness", "d": ["The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903566", "l": "positive regulation of protein localization to cilium", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cilium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000627", "l": "positive regulation of miRNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of miRNA catabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:1901891", "l": "regulation of cell septum assembly", "d": ["Any process that modulates the frequency, rate or extent of cell septum assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0006367", "l": "transcription initiation at RNA polymerase II promoter", "d": ["A transcription initiation process that takes place at a RNA polymerase II gene promoter. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "45.905473216285536", "identifiers": [{"i": "GO:0048519", "l": "negative regulation of biological process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. 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"negative regulation of eosinophil differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.67228564893351", "identifiers": [{"i": "GO:0030162", "l": "regulation of proteolysis", "d": ["Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036164", "l": "cell-abiotic substrate adhesion", "d": ["The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901958", "l": "negative regulation of cutin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1903988", "l": "iron ion export across plasma membrane", "d": ["The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901926", "l": "cadinene metabolic process", "d": ["The chemical reactions and pathways involving cadinene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000149", "l": "negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0010171", "l": "body morphogenesis", "d": ["The process in which the anatomical structures of the soma are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902957", "l": "negative regulation of mitochondrial electron transport, NADH to ubiquinone", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902457", "l": "negative regulation of stomatal opening", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0045144", "l": "meiotic sister chromatid segregation", "d": ["The cell cycle process in which sister chromatids are organized 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resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051622", "l": "negative regulation of norepinephrine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0006301", "l": "postreplication repair", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. 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The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901820", "l": "alpha-zeacarotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021948", "l": "inward migration of deep nuclear neurons", "d": ["The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0002517", "l": "T cell tolerance induction", "d": ["A process involving any mechanism for tolerance induction in T cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.432745995597372", "identifiers": [{"i": "GO:0009712", "l": "catechol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902894", "l": "negative regulation of miRNA transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microRNA (miRNA) gene transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.782293776020545", "identifiers": [{"i": "GO:0040011", "l": "locomotion", "d": ["Self-propelled movement of a cell or organism from one location to another."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180027", "l": "inner nuclear membrane-associated protein degradation pathway", "d": ["A protein quality control pathway that removes ubiquitinated proteins from the nuclear inner membrane before transferring them to the proteasome for degradation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0035283", "l": "central nervous system segmentation", "d": ["Division of the central nervous system into a series of semi-repetitive parts or segments."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033339", "l": "pectoral fin development", "d": ["The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990451", "l": "cellular stress response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046719", "l": "regulation by virus of viral protein levels in host cell", "d": ["Any virus-mediated process that modulates the levels of viral proteins in a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.168002017049517", "identifiers": [{"i": "GO:0033157", "l": "regulation of intracellular protein transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019604", "l": "toluene oxidation to catechol", "d": ["The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061820", "l": "telomeric D-loop disassembly", "d": ["A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019570", "l": "L-arabinose catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0033138", "l": "positive regulation of peptidyl-serine phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071237", "l": "cellular response to bacteriocin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.991992031210344", "identifiers": [{"i": "GO:0008360", "l": "regulation of cell shape", "d": ["Any process that modulates the surface configuration of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0044505", "l": "positive regulation of G protein-coupled receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0017185", "l": "peptidyl-lysine hydroxylation", "d": ["The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071226", "l": "cellular response to molecule of fungal origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901918", "l": "negative regulation of exoribonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072144", "l": "glomerular mesangial cell development", "d": ["The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.998276081196508", "identifiers": [{"i": "GO:0006119", "l": "oxidative phosphorylation", "d": ["The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. 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This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0036135", "l": "Schwann cell migration", "d": ["The orderly movement of a Schwann cell from one site to another. 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0032847", "l": "regulation of cellular pH reduction", "d": ["Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905528", "l": "positive regulation of Golgi lumen acidification", "d": ["Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009115", "l": "xanthine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.22821697197837", "identifiers": [{"i": "GO:0019083", "l": "viral transcription", "d": ["The process by which a viral genome, or part of a viral genome, is transcribed within the host cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2000962", "l": "positive regulation of cellooligosaccharide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0009409", "l": "response to cold", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1901975", "l": "glycerate transmembrane transport", "d": ["The process in which glycerate is transported across a membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003036", "l": "detection of pH by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0009103", "l": "lipopolysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900015", "l": 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Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0050433", "l": "regulation of catecholamine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of catecholamines."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045880", "l": "positive regulation of smoothened signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of smoothened signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0042946", "l": "glucoside transport", "d": ["The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903782", "l": "regulation of sodium ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010816", "l": "calcitonin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060882", "l": "basement membrane disassembly involved in semicircular canal fusion", "d": ["A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:1990192", "l": "collecting lymphatic vessel constriction", "d": ["A decrease in the diameter of collecting lymphatic vessels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0046823", "l": "negative regulation of nucleocytoplasmic transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042313", "l": "protein kinase C deactivation", "d": ["Any process resulting in the inhibition or termination of the activity of protein kinase C."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:1900813", "l": "monodictyphenone metabolic process", "d": ["The chemical reactions and pathways involving monodictyphenone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0043708", "l": "cell adhesion involved in biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002555", "l": "histamine secretion by platelet", "d": ["The regulated release of histamine by a platelet or group of platelets."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038001", "l": "paracrine signaling", "d": ["The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. 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Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0098939", "l": "dendritic transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in nerve cell dendrites."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0034698", "l": "response to gonadotropin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007111", "l": "meiosis II cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904749", "l": "regulation of protein localization to nucleolus", "d": ["Any process that modulates the frequency, rate or extent of protein localization to nucleolus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080024", "l": "indolebutyric acid metabolic process", "d": ["The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0007300", "l": "ovarian nurse cell to oocyte transport", "d": ["Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. 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The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0006829", "l": "zinc ion transport", "d": ["The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061179", "l": "negative regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003104", "l": "positive regulation of glomerular filtration", "d": ["Any process that activates or increases the frequency, rate or extent of glomerular filtration. 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This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035074", "l": "pupation", "d": ["The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. 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Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. 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Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904912", "l": "positive regulation of establishment of RNA localization to telomere", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902330", "l": "synthesis of RNA primer involved in bacterial-type DNA replication", "d": ["Any synthesis of RNA primer that is involved in bacterial-type DNA replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901059", "l": "p-hydroxyphenyl lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900326", "l": "positive regulation of maltotriulose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltotriulose transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002633", "l": "positive regulation of granuloma formation", "d": ["Any process that activates or increases the frequency, rate, or extent of granuloma formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.347862406647948", "identifiers": [{"i": "GO:0042044", "l": "fluid transport", "d": ["The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0006604", "l": "phosphoarginine metabolic process", "d": ["The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001106", "l": "regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0002714", "l": "positive regulation of B cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0045770", "l": "positive regulation of asymmetric cell division", "d": ["Any process that activates or increases the frequency, rate or extent of asymmetric cell division."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002565", "l": "somatic diversification of immune receptors via gene conversion", "d": ["The process in which immune receptor genes are diversified through gene conversion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0034465", "l": "response to carbon monoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905607", "l": "negative regulation of presynapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046069", "l": "cGMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902109", "l": "negative regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120237", "l": "terminal acetylenic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140570", "l": "extraction of mislocalized protein from mitochondrial outer membrane", "d": ["The removal of a mislocalized protein from the mitochondrial outer membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0140467", "l": "integrated stress response signaling", "d": ["The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. 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Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0140433", "l": "regulation of protein localization to meiotic spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071681", "l": "cellular response to indole-3-methanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "54.887895761975315", "identifiers": [{"i": "GO:0044255", "l": "cellular lipid metabolic process", "d": ["The chemical reactions and pathways involving lipids, as carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0072309", "l": "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0002654", "l": "positive regulation of tolerance induction dependent upon immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.052075658376204", "identifiers": [{"i": "GO:0002790", "l": "peptide secretion", "d": ["The controlled release of a peptide from a cell or a tissue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0090345", "l": "cellular organohalogen metabolic process", "d": ["The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000432", "l": "positive regulation of transcription from RNA polymerase II promoter by glucose", "d": ["Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904903", "l": "ESCRT III complex disassembly", "d": ["The disaggregation of an ESCRT III complex into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090107", "l": "regulation of high-density lipoprotein particle assembly", "d": ["Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000081", "l": "positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902550", "l": "lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis", "d": ["Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902161", "l": "positive regulation of cyclic nucleotide-gated ion channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905484", "l": "negative regulation of motor neuron migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0072024", "l": "macula densa development", "d": ["The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1903329", "l": "regulation of iron-sulfur cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0051103", "l": "DNA ligation involved in DNA repair", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:2001008", "l": "positive regulation of cellulose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060906", "l": "negative regulation of regulatory ncRNA-mediated heterochromatin formation", "d": ["Any process that decreases the frequency, rate or extent of non-coding RNA-mediated heterochromatin formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046600", "l": "negative regulation of centriole replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905494", "l": "negative regulation of G-quadruplex DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009290", "l": "DNA import into cell involved in transformation", "d": ["The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0072056", "l": "pyramid development", "d": ["The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. 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Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0031954", "l": "positive regulation of protein autophosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0021634", "l": "optic nerve formation", "d": ["The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0019388", "l": "galactose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0075263", "l": "oogonium development", "d": ["The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:2001074", "l": "regulation of metanephric ureteric bud development", "d": ["Any process that modulates the frequency, rate or extent of metanephric ureteric bud development."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002071", "l": "glandular epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. 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The fungiform papilla is a mushroom-shaped papilla of the tongue."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0048659", "l": "smooth muscle cell proliferation", "d": ["The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901272", "l": "2-dehydro-3-deoxy-D-gluconic acid metabolic process", "d": ["The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0098910", "l": "regulation of atrial cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. 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An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "61.548496485735448", "identifiers": [{"i": "GO:1901701", "l": "cellular response to oxygen-containing compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0050968", "l": "detection of chemical stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050984", "l": "peptidyl-serine sulfation", "d": ["The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1903930", "l": "regulation of pyrimidine-containing compound salvage", "d": ["Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034265", "l": "isopentenyl adenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0048172", "l": "regulation of short-term neuronal synaptic plasticity", "d": ["A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. 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This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071291", "l": "cellular response to selenium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046782", "l": "regulation of viral transcription", "d": ["Any process that modulates the frequency, rate or extent of the transcription of the viral genome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043108", "l": "pilus retraction", "d": ["The process of withdrawing a pilus back into a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0008359", "l": "regulation of bicoid mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0006476", "l": "protein deacetylation", "d": ["The removal of an acetyl group from a protein amino acid. 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The blood vessel is the vasculature carrying blood."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901920", "l": "peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity", "d": ["Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075299", "l": "positive regulation of zygospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0071605", "l": "monocyte chemotactic protein-1 production", "d": ["The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.042232280985438", "identifiers": [{"i": "GO:0007017", "l": "microtubule-based process", "d": ["Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110014", "l": "negative regulation of aggregation involved in sorocarp development", "d": ["Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. 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The aggregate is a multicellular structure that gives rise to the slug."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0046102", "l": "inosine metabolic process", "d": ["The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.906202702420444", "identifiers": [{"i": "GO:1903173", "l": "fatty alcohol metabolic process", "d": ["The chemical reactions and pathways involving fatty alcohol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071314", "l": "cellular response to cocaine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. 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In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071337", "l": "negative regulation of hair follicle cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048578", "l": "positive regulation of long-day photoperiodism, flowering", "d": ["Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. 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The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0035570", "l": "N-terminal peptidyl-serine methylation", "d": ["The methylation of the N-terminal serine of proteins."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1903110", "l": "regulation of single-strand break repair via homologous recombination", "d": ["Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0036364", "l": "transforming growth factor beta1 activation", "d": ["The release of transforming growth factor beta1 (TGF-beta1) from its latent state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0046385", "l": "deoxyribose phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1904354", "l": "negative regulation of telomere capping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0090016", "l": "regulation of leaflet formation", "d": ["Any process that modulates the frequency, rate or extent of leaflet formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.533519609617926", "identifiers": [{"i": "GO:0045786", "l": "negative regulation of cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032229", "l": "negative regulation of synaptic transmission, GABAergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902753", "l": "negative regulation of renal amino acid absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002487", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0045198", "l": "establishment of epithelial cell apical/basal polarity", "d": ["The specification and formation of the apicobasal polarity of an epithelial cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0043277", "l": "apoptotic cell clearance", "d": ["The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000011", "l": "vacuole inheritance", "d": ["The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0046162", "l": "heme C metabolic process", "d": ["The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0060140", "l": "modulation by virus of syncytium formation via plasma membrane fusion", "d": ["The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0033337", "l": "dorsal fin development", "d": ["The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0110002", "l": "regulation of tRNA methylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903912", "l": "negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.777623267158077", "identifiers": [{"i": "GO:0051701", "l": "biological process involved in interaction with host", "d": ["An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0002806", "l": "negative regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045467", "l": "R7 cell development", "d": ["The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. 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Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:2000847", "l": "negative regulation of corticosteroid hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0072050", "l": "S-shaped body morphogenesis", "d": ["The process in which the S-shaped body is generated and organized. 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"GO:1903985", "l": "regulation of intestinal D-glucose absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:1901388", "l": "regulation of transforming growth factor beta activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta activation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120041", "l": "positive regulation of macrophage proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060903", "l": "positive regulation of meiosis I", "d": ["Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process 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Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. 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A diuretic is an agent that promotes the excretion of urine through its effects on kidney function."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141095", "l": "retrotransposon silencing by DNA methylation-dependent heterochromatin formation", "d": ["A retrotransposon silencing mechanism in which a methylated cytosine residues in the genome promote heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0106074", "l": "aminoacyl-tRNA metabolism involved in translational fidelity", "d": ["Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.126913850795333", "identifiers": [{"i": "GO:0002369", "l": "T cell cytokine production", "d": ["Any process that contributes to cytokine production by a T cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0044579", "l": "butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.755473255981116", "identifiers": [{"i": "GO:0051259", "l": "protein complex oligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150101", "l": "regulation of microtubule anchoring at centrosome", "d": ["Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0060192", "l": "negative regulation of lipase activity", "d": ["Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0042665", "l": "regulation of ectodermal cell fate specification", "d": ["Any process that mediates the specification of a cell into an ectoderm cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1901941", "l": "(+)-epi-alpha-bisabolol metabolic process", "d": ["The chemical reactions and pathways involving (+)-epi-alpha-bisabolol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.558743890426797", "identifiers": [{"i": "GO:0044057", "l": "regulation of system process", "d": ["Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.305790483933691", "identifiers": [{"i": "GO:0006547", "l": "histidine metabolic process", "d": ["The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.709179502404908", "identifiers": [{"i": "GO:0019725", "l": "cellular homeostasis", "d": ["Any process involved in the maintenance of an internal steady state at the level of the cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080149", "l": "sucrose induced translational repression", "d": ["Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.130943529370171", "identifiers": [{"i": "GO:0006399", "l": "tRNA metabolic process", "d": ["The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.923594617603442", "identifiers": [{"i": "GO:0008655", "l": "pyrimidine-containing compound salvage", "d": ["Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008058", "l": "ocellus pigment granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0002078", "l": "membrane fusion involved in acrosome reaction", "d": ["The fusion of the plasma membrane of the sperm with the outer acrosomal membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1900521", "l": "regulation of response to amylopectin", "d": ["Any process that modulates the frequency, rate or extent of response to amylopectin."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0090691", "l": "formation of plant organ boundary", "d": ["The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0048439", "l": "flower morphogenesis", "d": ["The process in which the anatomical structures of the flower are generated and organized."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000016", "l": "negative regulation of determination of dorsal identity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0015762", "l": "rhamnose transmembrane transport", "d": ["The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901741", "l": "positive regulation of myoblast fusion", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast fusion."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.051624214255", "identifiers": [{"i": "GO:0006261", "l": "DNA-templated DNA replication", "d": ["A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009819", "l": "drought recovery", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:1905377", "l": "response to D-galactose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006018", "l": "2-deoxyribose 1-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0051123", "l": "RNA polymerase II preinitiation complex assembly", "d": ["The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which may include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH complexes). The PIC engages RNA polymerase II on its DNA template strand and sparks polymerization of the first few RNA nucleotides of the nascent transcript, of which 8 are base-paired with the DNA template within a DNA bubble. PIC assembly may result in a pause step, which marks the end of the PIC assembly and may be followed by promoter clearance (exact synonym: promoter escape). For RNA polymerase II PIC assembly is preceded by the formation of a nucleosome-free region that allows the transcription machinery to access the promoter DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0071331", "l": "cellular response to hexose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0016203", "l": "muscle attachment", "d": ["The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0009802", "l": "cinnamic acid ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0008334", "l": "histone mRNA metabolic process", "d": ["The chemical reactions and pathways involving an mRNA encoding a histone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0040037", "l": "negative regulation of fibroblast growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904791", "l": "negative regulation of shelterin complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090122", "l": "cholesterol ester hydrolysis involved in cholesterol transport", "d": ["The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0090232", "l": "positive regulation of spindle checkpoint", "d": ["Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.960002279600147", "identifiers": [{"i": "GO:0030258", "l": "lipid modification", "d": ["The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.582265651609575", "identifiers": [{"i": "GO:0045981", "l": "positive regulation of nucleotide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.552154022789225", "identifiers": [{"i": "GO:0062208", "l": "positive regulation of pattern recognition receptor signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0071867", "l": "response to monoamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120166", "l": "protoperithecium formation", "d": ["The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000296", "l": "spermine transport", "d": ["The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070710", "l": "RNA uridine deletion", "d": ["The modification of an RNA molecule by removal of a uridine nucleotide."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0061319", "l": "nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0044860", "l": "protein localization to plasma membrane raft", "d": ["A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0001997", "l": "positive regulation of the force of heart contraction by epinephrine-norepinephrine", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0030047", "l": "actin modification", "d": ["Covalent modification of an actin molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043538", "l": "regulation of actin phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.850480343987797", "identifiers": [{"i": "GO:0075247", "l": "aeciospore formation", "d": ["The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.024411547311772", "identifiers": [{"i": "GO:0048316", "l": "seed development", "d": ["The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070729", "l": "cyclic nucleotide transport", "d": ["The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904531", "l": "positive regulation of actin filament binding", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament binding."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0070880", "l": "fungal-type cell wall beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0000487", "l": "maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036291", "l": "protein cis-autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own amino acid residues."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0030640", "l": "polyketide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.599657566792573", "identifiers": [{"i": "GO:0032109", "l": "positive regulation of response to nutrient levels", "d": ["Any process that activates or increases the frequency, rate or extent of a response to nutrient levels."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030632", "l": "D-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.921857375477728", "identifiers": [{"i": "GO:1901334", "l": "lactone metabolic process", "d": ["The chemical reactions and pathways involving lactone."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.498354445609536", "identifiers": [{"i": "GO:0018993", "l": "somatic sex determination", "d": ["The determination of sex and sexual phenotypes in an organism's soma."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0106057", "l": "negative regulation of calcineurin-mediated signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007302", "l": "nurse cell nucleus anchoring", "d": ["Attachment of the nurse cell nucleus to the plasma membrane."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036098", "l": "male germ-line stem cell population maintenance", "d": ["The process by which an organism or tissue maintains a population of male germ-line stem cells."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903452", "l": "positive regulation of G1 to G0 transition", "d": ["Any process that activates or increases the frequency, rate or extent of G1 to G0 transition."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062096", "l": "kinetochore disassembly", "d": ["The disaggregation of a kinetochore into its constituent components."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901418", "l": "positive regulation of response to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of response to ethanol."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0007190", "l": "activation of adenylate cyclase activity", "d": ["Any process that initiates the activity of the inactive enzyme adenylate cyclase."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.157025479615683", "identifiers": [{"i": "GO:0090069", "l": "regulation of ribosome biogenesis", "d": ["Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.772337719465526", "identifiers": [{"i": "GO:0001963", "l": "synaptic transmission, dopaminergic", "d": ["The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. 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Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015946", "l": "methanol oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.377736627990572", "identifiers": [{"i": "GO:0030588", "l": "pseudocleavage", "d": ["Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080035", "l": "2-hydroxy-but-3-enyl glucosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990689", "l": "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0002721", "l": "regulation of B cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of B cell cytokine production."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0018969", "l": "thiocyanate metabolic process", "d": ["The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090606", "l": "single-species surface biofilm formation", "d": ["A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001079", "l": "nitrogen catabolite regulation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062165", "l": "positive regulation of pseudohyphal septin ring assembly", "d": ["Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006217", "l": "deoxycytidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090144", "l": "mitochondrial nucleoid organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. 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Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000012", "l": "regulation of auxin polar transport", "d": ["Any process that modulates the frequency, rate or extent of auxin polar transport."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018984", "l": "naphthalenesulfonate metabolic process", "d": ["The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.775903698273282", "identifiers": [{"i": "GO:0021550", "l": "medulla oblongata development", "d": ["The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. 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Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0003301", "l": "physiological cardiac muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0010162", "l": "seed dormancy process", "d": ["A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. 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Occurs in non-enveloped prokaryotic viruses."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:0001937", "l": "negative regulation of endothelial cell proliferation", "d": ["Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106116", "l": "positive regulation of mitotic cohesin dsDNA (leading strand) loading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071255", "l": "Cvt vesicle assembly", "d": ["A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072461", "l": "response to meiotic recombination checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.45013791078037", "identifiers": [{"i": "GO:0021543", "l": "pallium development", "d": ["The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. 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This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060335", "l": "positive regulation of type II interferon-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.802976799984464", "identifiers": [{"i": "GO:0003032", "l": "detection of oxygen", "d": ["The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.174417394798667", "identifiers": [{"i": "GO:0060502", "l": "epithelial cell proliferation involved in lung morphogenesis", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.300839195380277", "identifiers": [{"i": "GO:0045622", "l": "regulation of T-helper cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper cell differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.071377031489931", "identifiers": [{"i": "GO:0070920", "l": "regulation of regulatory ncRNA processing", "d": ["Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:1901900", "l": "regulation of protein localization to cell division site", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell division site."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.275720515981703", "identifiers": [{"i": "GO:0090398", "l": "cellular senescence", "d": ["A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110125", "l": "negative regulation of myotube cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150141", "l": "negative regulation of CD86 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900004", "l": "negative regulation of serine-type endopeptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090326", "l": "positive regulation of locomotion involved in locomotory behavior", "d": ["Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.749177222804775", "identifiers": [{"i": "GO:1904760", "l": "regulation of myofibroblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of myofibroblast differentiation."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044861", "l": "protein transport into plasma membrane raft", "d": ["The directed movement of a protein into a plasma membrane raft."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.425240171993906", "identifiers": [{"i": "GO:0140735", "l": "lovastatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.173931203323974", "identifiers": [{"i": "GO:0060601", "l": "lateral sprouting from an epithelium", "d": ["The process in which a branch forms along the side of an epithelium."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902758", "l": "bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034476", "l": "U5 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U5 snRNA molecule."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046805", "l": "protein-heme linkage via 1'-L-histidine", "d": ["The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine)."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900332", "l": "positive regulation of methane biosynthetic process from trimethylamine", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine."], "t": []}], "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.700960687975609", "identifiers": [{"i": "GO:0043940", "l": "regulation of sexual sporulation resulting in formation of a cellular spore", "d": ["Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis."], "t": []}], "taxa": []}