name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Caenorhabditis elegans)


name: an [alpha-factor](in) + ATP + H2O <=> ADP + an [alpha-factor](out) + H(+) + phosphate


name: Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)


name: p-T68-CHEK2 autophosphorylates (Gallus gallus)


name: WIPI2 binds ATG12:ATG5:ATG16L (Sus scrofa)


name: 7alpha-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + L-methionine + S-adenosyl-L-homocysteine => L-homocysteine + S-adenosyl-L-methionine


name: ZEB2 binds SP1 (Drosophila melanogaster)


name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Sus scrofa)


name: USP33 deubiquitinates ROBO1 (Drosophila melanogaster)


name: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H(+) => 1D-myo-inositol 1,3,4-trisphosphate + ATP


name: 3-hydroxyphenylacetate + H(+) + NADH + O2 = H2O + homogentisate + NAD(+)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Gallus gallus)


name: PITPNM1,2,3 exchange PI for PA (Bos taurus)


name: (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] => butanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: cholate + NADP(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADPH


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Homo sapiens)


name: H(+)(out) + rifampicin(in) => H(+)(in) + rifampicin(out)


name: D-serine(out) + L-alanine(in) = D-serine(in) + L-alanine(out)


name: H(+) + NADP(+) + 2 reduced [adrenodoxin] = NADPH + 2 oxidized [adrenodoxin]


name: STARD5 binds DCA, LCA (Caenorhabditis elegans)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Canis familiaris)


name: GOT2 dimer deaminates L-Asp (Xenopus tropicalis)


name: HEXB cleaves the terminal GalNAc from DS (Caenorhabditis elegans)


name: BRAP autoubiquitinates (Drosophila melanogaster)


name: cytochalasin Z16 + H2O + NADP(+) => H(+) + iso-precytochalasin + NADPH + O2


name: ATP7A transfers Cu from ATOX1 to SOD3 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + L-tryptophyl-[protein] => (2S,3R)-3-farnesyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate


name: Translocation of NFATC1:CaN:CaM to nucleus (Homo sapiens)


name: RNF181 polyubiquinates BCL10 (Canis familiaris)


name: cis-(homo)3aconitate + H2O => (2R,3S)-iso(homo)3citrate


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Xenopus tropicalis)


name: 3,4-dehydrothiomorpholine-3-carboxylate + 2 H(+) + NADH => (3R)-1,4-thiomorpholine-3-carboxylate + NAD(+)


name: (S)-3-(imidazol-5-yl)lactate + NADP(+) => 3-(imidazol-5-yl)pyruvate + H(+) + NADPH


name: a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ATP + glutathione(in) + glycochenodeoxycholate(in) + H2O = ADP + glutathione(out) + glycochenodeoxycholate(out) + H(+) + phosphate


name: Caspase-8 activates BID by cleavage (Sus scrofa)


name: G alpha (q) binds to Trio family RhoGEFs (Rattus norvegicus)


name: H(+)(out) + sucrose(in) => H(+)(in) + sucrose(out)


name: 4-coumaroyl-CoA + agmatine <=> CoA + H(+) + N-(4-guanidinobutyl)-4-hydroxycinnamamide


name: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Sus scrofa)


name: "Site specific endodeoxyribonucleases: cleavage is sequence specific"


name: (S)-2-benzoylsuccinyl-CoA + CoA => benzoyl-CoA + succinyl-CoA


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Bos taurus)


name: arginine + H2O => ornithine + urea [ARG2] (Canis familiaris)


name: SHC1 phosphorylation by phosphorylated EGFR (Rattus norvegicus)


name: a 3'-end uridylyl-adenosine-RNA <=> a 3'-end 2',3'-cyclophospho-uridine-RNA + adenosine


name: ergosterol + NADP(+) <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+) + NADPH


name: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> alpha-D-ribose 1,5-bisphosphate + H(+)


name: Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) (Homo sapiens)


name: HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH (Homo sapiens)


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine <=> diphthine methyl ester-[translation elongation factor 2] + 3 H(+) + 4 S-adenosyl-L-homocysteine


name: 2-oxoglutarate + a (3R)-3-{[carboxy(hydroxy)methyl]amino}fatty acid + O2 = a (3R)-3-isocyanyl-fatty acid + 2 CO2 + 2 H2O + succinate


name: (5Z)-tetradecenoyl-CoA + (R)-carnitine <=> CoA + O-(5Z)-tetradecenoyl-(R)-carnitine


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Mus musculus)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Homo sapiens)


name: ABCA4 mediates atRAL transport (Homo sapiens)


name: 1D-5-O-methyl-myo-inositol + NAD(+) => 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH


name: 2 Fe(III)-[cytochrome c3] + hydrogen sulfide + sulfite = 2 Fe(II)-[cytochrome c3] + thiosulfate


name: (S)-1-hydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-cis-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase]


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone <=> 2beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O <=> 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate


name: 1,4-dihydroxy-2-naphthoate + all-trans-octaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-8 + CO2 + diphosphate


name: H(+)(in) + phosphate(in) + sulfate(out) <=> H(+)(out) + phosphate(out) + sulfate(in)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Drosophila melanogaster)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Xenopus tropicalis)


name: C4 deamination of cytidine (Canis familiaris)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate


name: an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) <=> H(+) + N-terminal L-arginyl-L-amino acid-[protein] + tRNA(Arg)


name: propanal + pyruvate => (S)-4-hydroxy-2-oxohexanoate


name: G/T mismatch-specific thymine-DNA glycosylase activity


name: [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + H2O <=> (9Z)-hexadecenoate + [Wnt protein]-L-serine + H(+)


name: STAT1 and STAT3 dimers translocate to the nucleus (Canis familiaris)


name: aurachin C + H(+) + NADPH + O2 => aurachin C epoxide + H2O + NADP(+)


name: CoA + H(+) + tetracosanoate => H2O + tetracosanoyl-CoA


name: Expression of Calreticulin (Homo sapiens)


name: aclacinomycin S + dTDP + H(+) => aclacinomycin T + dTDP-2-deoxy-beta-L-fucose


name: FOXO1,FOXO3,FOXO4 bind IGFBP1 gene promoter (Homo sapiens)


name: 4-deoxy-4-sulfo-D-erythrose + D-xylulose 5-phosphate => 6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate


name: Electron transfer from ubiquinol to cytochrome c of complex III (Saccharomyces cerevisiae)


name: Myosin phosphatase dephosphorylates PLK1 (Bos taurus)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Canis familiaris)


name: CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D (Mus musculus)


name: CSNK1A1 and ADRBK1 dissociate from p-SMO dimer (Sus scrofa)


name: alpha-D-galactose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-D-galactose


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + octanoate => 1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Sus scrofa)


name: Journey of cargo through Golgi complex (Homo sapiens)


name: Deubiquitinated PTEN translocates to the cytosol (Sus scrofa)


name: Cho is phosphorylated to PCho by CHK dimer (Caenorhabditis elegans)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O => a 1-O-alkyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: tri-trans,hepta-cis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine => N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UMP


name: ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase]


name: "[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase"


name: ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex (Bos taurus)


name: USP17L2 deubiquitinates RCE1 (Saccharomyces cerevisiae)


name: Dentin matrix protein 1 binds integrin alphaVbeta3 (Mus musculus)


name: FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 (Homo sapiens)


name: tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity


name: chenodeoxycholoyl-CoA + NAD(+) = 7alpha-hydroxy-3-oxochol-24-oyl-CoA + H(+) + NADH


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Schizosaccharomyces pombe)


name: RGGT:CHM binds RABs (Plasmodium falciparum)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + squalene = (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b5] + H2O


name: H(+) + NAD(+) + 2 reduced [nitric oxide reductase rubredoxin domain] => NADH + 2 oxidized [nitric oxide reductase rubredoxin domain]


name: (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O => (2Z)-2-hydroxypenta-2,4-dienoate + H(+) + succinate


name: RAC1 binds effectors at the plasma membrane (Drosophila melanogaster)


name: transmembrane receptor protein tyrosine kinase inhibitor activity


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Canis familiaris)


name: Phosphorylation of WWTR1 (TAZ) by LATS2 (Homo sapiens)


name: Phosphorylation of TSC2 by PKB (Mus musculus)


name: B-WICH recruits histone acetyltransferases (Rattus norvegicus)


name: (19R,20S)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: CANX dissociates from IL27:EBI3 (Bos taurus)


name: The Ligand:GPCR:Gz complex dissociates (Mus musculus)


name: 1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + H2O2 => glycolaldehyde + guaiacol + H2O + vanillin


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Canis familiaris)


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Rattus norvegicus)


name: SeMet is converted to AdoSeMet by MAT (Homo sapiens)


name: (4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]


name: APEH hydrolyses NAc-Ser-protein (Homo sapiens)


name: PRODH oxidises L-Pro to 1PYR-5COOH (Mus musculus)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Saccharomyces cerevisiae)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: Phosphorylation of CRMPs by Cdk5 (Gallus gallus)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Homo sapiens)


name: DCN binds collagen I, II, III, VI fibrils (Sus scrofa)


name: (R)-3-hydroxybutanoate + CoA + H(+) => (3R)-3-hydroxybutanoyl-CoA + H2O


name: HMOX1 translocates from the cytosol to the nucleoplasm (Sus scrofa)


name: 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide d + H(+) + L-methionine => a 7(1)-hydroxybacteriochlorophyllide d + H2O + S-adenosyl-L-methionine


name: a globoside GalGb4Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine => a globoside GlcNAc-GalGb4Cer (d18:1(4E)) + H(+) + UDP


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O = (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: H2O + leukotriene C4 => L-glutamate + leukotriene D4


name: PGLYRP1 binds bacterial peptidoglycan (Sus scrofa)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Bos taurus)


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Sus scrofa)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Saccharomyces cerevisiae)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Homo sapiens)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+) => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP-beta-L-fucose


name: AKT1 phosphorylates eNOS (Rattus norvegicus)


name: Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm (Danio rerio)


name: H(+) + NADPH + O2 + octan-3-one = H2O + NADP(+) + pentyl propanoate


name: ERBB4s80 binds YAP1 (Caenorhabditis elegans)


name: Beta-catenin migrates to the nucleus (Drosophila melanogaster)


name: H2O + N-octanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-octanoyl ethanolamine


name: OPN (osteopontin) degradation by MMP3, MMP7 (Gallus gallus)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Xenopus tropicalis)


name: (R)-5-phosphomevalonate + ATP => (R)-5-diphosphomevalonate + ADP


name: Tyrosine is diiodinated (Canis familiaris)


name: L-cysteate + phosphate => H(+) + O-phospho-L-serine + sulfite


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Danio rerio)


name: dimethyl sulfide + 2 Fe(III)-[cytochrome c2] + H2O = dimethyl sulfoxide + 2 Fe(II)-[cytochrome c2] + 2 H(+)


name: "dimethyl sulfide:cytochrome c2 reductase"


name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Canis familiaris)


name: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 => CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit]


name: GLB1 hydrolyses linker chain(2) (Mus musculus)


name: glycine + hexacosanoyl-CoA => CoA + H(+) + N-hexacosanoylglycine


name: (20S)-ginsenoside Rb1 + 2 H2O <=> 2 D-glucose + gypenoside LXXV


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Bos taurus)


name: DHFR2 reduces FOLA to DHF (Drosophila melanogaster)


name: Fibrillin-1 binds integrins (Canis familiaris)


name: Netrin-4 binds DCC/UNC5A (Rattus norvegicus)


name: 3-oxocyclopentanecarbonitrile + 2 H2O => 3-oxocyclopentanecarboxylate + NH4(+)


name: Interaction of SHP1 and KIT (Rattus norvegicus)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Dictyostelium discoideum)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: a dicarboxylate(in) + sulfate(out) <=> a dicarboxylate(out) + sulfate(in)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Drosophila melanogaster)


name: NFE2 binds the beta globin locus control region (Drosophila melanogaster)


name: The high affinity receptor complex binds to G-protein (Mus musculus)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Canis familiaris)


name: Ubiquitinated IkB is degraded (Bos taurus)


name: an alcohol + D-glucuronate => an alpha-D-glucuronoside + H2O


name: MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: Bcl-2 and Bcl-XL bind NLRP1 (Gallus gallus)


name: SRC family kinases phosphorylate ERBB2 (Sus scrofa)


name: NADP(+) + UDP-N-acetyl-alpha-D-quinovosamine = H(+) + NADPH + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose


name: EP3 subtype prostaglandin E2 receptor binding


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Schizosaccharomyces pombe)


name: ADP-5-ethyl-4-methylthiazole-2-carboxylate + H(+) + 3 H2O + nicotinamide => glycine + hydrogen sulfide + NAD(+)


name: SARS-CoV-1 3a tetramer induces potassium efflux (Homo sapiens)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)


name: a short-chain fatty acyl-CoA + H2O => a short-chain fatty acid + CoA + H(+)


name: NAD(+) + propanoyl-CoA = acryloyl-CoA + H(+) + NADH


name: H(+) + kaempferide + S-adenosyl-L-homocysteine => kaempferol + S-adenosyl-L-methionine


name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Homo sapiens)


name: 2 H(+) + roseoflavin + 2 S-adenosyl-L-homocysteine => 8-amino-8-demethylriboflavin + 2 S-adenosyl-L-methionine


name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Mus musculus)


name: 2-demethylmenaquinol-9 + S-adenosyl-L-methionine => H(+) + menaquinol-9 + S-adenosyl-L-homocysteine


name: PLK3 phosphorylates CDC25C (Rattus norvegicus)


name: Galanin receptors can bind galanin (Rattus norvegicus)


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Gallus gallus)


name: a ganglioside GD1a (d18:1(4E)) + CMP + H(+) => a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: CTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin cytosine dinucleotide


name: (4S)-4-hydroxy-L-glutamate + H(+) + NADPH => (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + 2 H2O + NADP(+)


name: p-benzoquinone reductase (NADPH) activity


name: RAC1:GTP binds NOX1 complex (Bos taurus)


name: NCOA3 binds ESR1:estrogen:TFGA gene (Homo sapiens)


name: Aquaporins passively transport water out of cells (Sus scrofa)


name: glyoxylate + L-kynurenine => glycine + H2O + kynurenate


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: D-ribulose 5-phosphate + H(+) + NADH => D-ribitol 5-phosphate + NAD(+)


name: ethylene glycol + NAD(+) <=> glycolaldehyde + H(+) + NADH


name: (9Z,12Z,15Z)-octadecatrien-1-ol + 1-hexadecanoylglycerone 3-phosphate <=> 1-O-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate + H(+) + hexadecanoate


name: 1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + a di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H(+)


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)


name: DHAP is converted to 1-acyl GO3P by GNPAT (Caenorhabditis elegans)


name: (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Schizosaccharomyces pombe)


name: [aequorin] + 3 Ca(2+) = [aequorin]--dioxetanone


name: (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] => phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit]


name: adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine => H2O + N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine


name: Dephosphorylation of phospho-Cdh1 (Mus musculus)


name: Transphosphorylation of pLIMK1 (Bos taurus)


name: S-Farn-Me KRAS4B binds calmodulin (Bos taurus)


name: ABCB4 transports PC from plasma membrane to extracellular region (Gallus gallus)


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate = 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate


name: scyllo-inosose = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O


name: Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol (Homo sapiens)


name: TP53 stimulates NLRC4 expression (Homo sapiens)


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Sus scrofa)


name: uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid (Canis familiaris)


name: hydroxylamine + O2 => H(+) + H2O + nitrite


name: COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates (Canis familiaris)


name: 17beta-estradiol 3-O-(beta-D-glucuronate) 17-sulfate + 3'-phosphoadenylyl sulfate => 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) 17-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: A + all-trans-7,8-dihydroretinol = AH2 + all-trans-retinol


name: CR2:C3d,C3dg,iC3b binds CD19:CD81 (Canis familiaris)


name: ATP + H2O + urate(in) <=> ADP + H(+) + phosphate + urate(out)


name: adenosine 3',5'-bisphosphate + H(+) + quercetin 3,3'-bissulfate => 3'-phosphoadenylyl sulfate + quercetin 3-sulfate


name: p-DAPP1 (p-BAM32) binds PLCG2 (Mus musculus)


name: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + H(+)


name: ATP + L-homoserine => ADP + H(+) + O-phospho-L-homoserine


name: Homodimerization  of DFF40 (Rattus norvegicus)


name: Cargo Sequestration (Dictyostelium discoideum)


name: RNA(n) + UTP <=> diphosphate + RNA(n)-3'-uridine ribonucleotide


name: NPAS4:ARNT2 binds BDNF gene promoter (Homo sapiens)


name: CCND3,(CCND1,CCND2) binds RUNX1 (Homo sapiens)


name: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) => (S)-allantoin + CO2


name: CO2 + NADH + propanoyl-CoA => (S)-2-methyl-3-oxopropanoate + CoA + NAD(+)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Gallus gallus)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Sus scrofa)


name: [(1->4)-alpha-D-galacturonosyl](n) + H2O <=> [(1->4)-alpha-D-galacturonosyl](n-2) + alpha-D-galacturonosyl-(1->4)-D-galacturonate


name: Activation of TAK1 complex bound to pUb-TRAF6 (Gallus gallus)


name: (20S)-ginsenoside Rd + H2O = (20S)-ginsenoside Rg3 + D-glucose


name: p-Y693-STAT4 dissociates after IL12:IL12R interaction (Gallus gallus)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Xenopus tropicalis)


name: 3-oxopropanoate + L-glutamate => 2-oxoglutarate + beta-alanine


name: diphosphate + GTP + H(+) => guanosine 3'-diphosphate 5'-triphosphate + H2O


name: (25R)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25R)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (9Z,12Z)-octadecadienoate + glycerol + H(+) => 2-(9Z,12Z-octadecadienoyl)-glycerol + H2O


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Caenorhabditis elegans)


name: 2 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: PARK2 K63-Ubiquitinates SNCAIP (Homo sapiens)


name: Recruitment of HDAC1 by p107 (RBL1) (Rattus norvegicus)


name: H2O + sitosteryl 3-beta-D-glucoside = D-glucose + sitosterol


name: CoA + N-acetyl-4-O-acetylneuraminate => acetyl-CoA + N-acetylneuraminate


name: Translocation of RIAM to plasma membrane (Caenorhabditis elegans)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GM1 (d18:1(4E)) + CMP + H(+)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Canis familiaris)


name: HGFAC cleaves pro-HGF to form HGF dimer (Gallus gallus)


name: Activation of PAKs by RAC1 and CDC42 (Mus musculus)


name: TRIM33 monoubiquitinates SMAD4 (Homo sapiens)


name: Loss of SAR1B GTPase (Schizosaccharomyces pombe)


name: a flavonol 3-O-beta-D-glucoside + H(+) + UDP => a flavonol + UDP-alpha-D-glucose


name: H2O + L-alanyl-L-cysteine <=> L-alanine + L-cysteine


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Saccharomyces cerevisiae)


name: AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate => A + semiviriditoxin


name: Cannabinoid receptors can bind cannabinoids (Sus scrofa)


name: glutarate(in) + xanthurenate(out) => glutarate(out) + xanthurenate(in)


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Bos taurus)


name: AFG3L2 binds mitochondrial matrix proteins (Caenorhabditis elegans)


name: 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: acetone + H(+) + NADH + O2 <=> H2O + hydroxyacetone + NAD(+)


name: 3,4-dihydroxybenzoate + O2 <=> 3-carboxy-cis,cis-muconate + 2 H(+)


name: 3-hydroxypropanal + H2O + NAD(+) <=> 3-hydroxypropanoate + 2 H(+) + NADH


name: oligopeptide transmembrane transporter activity


name: [protein]-disulfide + H2O + phylloquinone <=> 2,3-epoxyphylloquinone + [protein]-dithiol


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycerol + H(+) + phosphocholine


name: (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+) <=> catechol + H(+) + NADPH


name: 2 H(+) + hexanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 5-hexenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Transport of MHC heterotrimer to ER exit site (Mus musculus)


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Dictyostelium discoideum)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 oxidized [adrenodoxin] => (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Homo sapiens)


name: carnosine + S-adenosyl-L-methionine <=> anserine + H(+) + S-adenosyl-L-homocysteine


name: NEIL1 cleaves FapyG from damaged DNA (Canis familiaris)


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Canis familiaris)


name: ATP + chloramphenicol(in) + H2O <=> ADP + chloramphenicol(out) + H(+) + phosphate


name: SERPING1 variant does not bind kallikrein (Homo sapiens)


name: 3-phosphoglycerate <=> 2-phosphoglycerate (Gallus gallus)


name: Exocytosis of secretory granule membrane proteins (Schizosaccharomyces pombe)


name: NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: (20S)-protopanaxatriol + UDP-alpha-D-glucose => (20S)-ginsenoside F1 + H(+) + UDP


name: Initial activation of proMMP13 by MMP3 (Homo sapiens)


name: K63polyUb-IRAK1 dissociates (Homo sapiens)


name: 3-oxo-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + CO2 + CoA => (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H(+) + malonyl-CoA


name: deoxycholoyl-24-O-(beta-D-glucuronate) + UDP => deoxycholate + UDP-alpha-D-glucuronate


name: Exocytosis of specific granule lumen proteins (Plasmodium falciparum)


name: acrolein + N-(4-aminobutyl)-3-aminopropanal => spermine dialdehyde


name: scyllo-inosose <=> 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O


name: deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Canis familiaris)


name: ERBB4 forms heterodimers with ERBB3 (Gallus gallus)


name: alpha-pinene oxide => (Z)-2-methyl-5-isopropylhexa-2,5-dienal


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Rattus norvegicus)


name: 3-oxoisopentadecanoyl-CoA + CO2 + CoA => 11-methyldodecanoyl-CoA + H(+) + malonyl-CoA


name: ALDH1A1 oxidises GA to DGA (Homo sapiens)


name: 3beta,7alpha-dihydroxyandrost-5-en-17-one + NADP(+) <=> 3beta-hydroxy-5-androstene-7,17-dione + H(+) + NADPH


name: 4 PBGs bind to form HMB (Canis familiaris)


name: PP5 dephosphorylates RAF1 S338 (Homo sapiens)


name: (PTN,MDK):PTPRZ oligomerizes (Gallus gallus)


name: S-Farn-Me KRAS4B binds calmodulin (Homo sapiens)


name: all-trans-4,4'-diaponeurosporene + FAD + H(+) <=> all-trans-4,4'-diapolycopene + FADH2


name: H2O + N-terminal L-glutaminyl-[protein] => N-terminal L-glutamyl-[protein] + NH4(+)


name: Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase (Homo sapiens)


name: D-xylulose 5-phosphate => D-ribulose 5-phosphate


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Sus scrofa)


name: PLC-gamma1 hydrolyses PIP2 (Dictyostelium discoideum)


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Sus scrofa)


name: EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 binds SHC1 (Homo sapiens)


name: alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose => alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose


name: H2O + NAD(+) + serinol => dihydroxyacetone + H(+) + NADH + NH4(+)


name: Cytosolic DUSPs dephosphorylate MAPKs (Plasmodium falciparum)


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Saccharomyces cerevisiae)


name: Autophosphorylation of PAK1 (Sus scrofa)


name: Active FLT3 phosphorylates CDKN1B (Mus musculus)


name: H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein] = N(6)-(D-fructosyl)-L-lysyl-[protein] + phosphate


name: SIRP beta binds TYROBP (Rattus norvegicus)


name: beta-D-glucuronate + NAD(+) = D-glucaro-1,5-lactone + H(+) + NADH


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Dictyostelium discoideum)


name: ATP + H(+) + IC-asc-C7 => diphosphate + IC-asc-C7-AMP


name: Collagen type XV restin release (Canis familiaris)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Homo sapiens)


name: chloride + FADH2 + L-tryptophan + O2 = 5-chloro-L-tryptophan + FAD + 2 H2O


name: (2E)-geraniol + NADP(+) <=> (2E)-geranial + H(+) + NADPH


name: (1S,4S)-5-oxo-1,2-campholide + FMN + H(+) + H2O => (1S,4S)-bornane-2,5-dione + FMNH2 + O2


name: TDG excises 5-carboxylcytosine (Xenopus tropicalis)


name: TRAF6 binding leads to IRAK1:TRAF6 release (Sus scrofa)


name: 9H-carbazole + H(+) + NADPH + O2 <=> 2'-aminobiphenyl-2,3-diol + NADP(+)


name: Expression of EMX2 in the nephric duct (Homo sapiens)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Sus scrofa)


name: 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + A = (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA + AH2


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Drosophila melanogaster)


name: Dissociation of the COP1-p53 complex (Sus scrofa)


name: GBA3 hydrolyzes GlcCer (cytosol) (Canis familiaris)


name: triplet codon-amino acid adaptor activity


name: Factor B binds to surface-associated C3b (Danio rerio)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Drosophila melanogaster)


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Gallus gallus)


name: (2S,4S)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine => (2S)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA = (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O


name: CO2 + dihydroxyacetone phosphate + NADH => 4-O-phospho-D-threonate + NAD(+)


name: ADP + D-alanyl-D-serine + H(+) + phosphate => ATP + D-alanine + D-serine


name: PTK2 binds activated MET (Gallus gallus)


name: (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) = catechol + CO2 + NADH


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Rattus norvegicus)


name: 2-amino-2-deoxy-D-gluconate => (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate + H2O


name: SERPINB13 binds CTSK (Rattus norvegicus)


name: 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity


name: H2O + triacetin = acetate + diacetylglycerol + H(+)


name: [(2E,6E,10E)-geranylgeranyl]-L-cysteine + H2O + O2 <=> (2E,6E,10E)-geranylgeranial + H2O2 + L-cysteine


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Homo sapiens)


name: biphenyl-2,3-diol + H(+) + NADH => (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: 9,10-epoxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-9,10-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Sus scrofa)


name: Activation of PAK by Rac1 (Canis familiaris)


name: Ca2+ influx through voltage gated Ca2+ channels (Bos taurus)


name: ESR1 binds to TGFA gene promoter (Homo sapiens)


name: NAD(+) + octan-1-ol = H(+) + NADH + octanal


name: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH


name: D-maltotriono-1,5-lactone + H2O2 => D-maltotriose + O2


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Bos taurus)


name: 4 ATP <=> cyclic tetraadenylate + 4 diphosphate


name: Phosphorylated STAT5 is released (Rattus norvegicus)


name: PAN2-PAN3 complex partially deadenylates mRNA (Saccharomyces cerevisiae)


name: ubiquitin modification-dependent histone binding


name: a quinone + H2O + sulfite <=> a quinol + sulfate


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Canis familiaris)


name: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate


name: C2CD3 binds the mother centriole (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Mus musculus)


name: 7-O-geranyl-2-O,3-dimethylflaviolin + diphosphate => (2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin + H(+)


name: GLB1 hydrolyzes SapB/C:LacCer (Canis familiaris)


name: N-carbamoyl-2-oxoglycine + phosphate => carbamoyl phosphate + oxamate


name: (Z)-glucotropeolin + H2O => (Z)-phenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: MDM2 forms homo- or heterodimers (Homo sapiens)


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Drosophila melanogaster)


name: a 2,3-saturated acyl-[ACP] + NAD(+) <=> a (2E)-enoyl-[ACP] + H(+) + NADH


name: histidine => urocanate + NH4+ (Bos taurus)


name: E2-mediated FOS gene expression (Homo sapiens)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Mus musculus)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Bos taurus)


name: 10-formyldihydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide => 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 7,8-dihydrofolate


name: H(+) + orotidine 5'-phosphate = CO2 + UMP


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-cinerolone = cinerin II + CoA


name: HSD11B2 dehydrogenates PREDL to PREDN (Mus musculus)


name: SLIT2 gene expression is stimulated by ISL1 (Homo sapiens)


name: Recruitment of  RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Canis familiaris)


name: ULK complex translocates to the ER (Rattus norvegicus)


name: DKK promotes clathrin-dependent internalization of LRP6 (Sus scrofa)


name: dihydrocarveol + NAD(+) => dihydrocarvone + H(+) + NADH


name: p-AMPK:AMP binds the ULK complex (Drosophila melanogaster)


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)


name: 2 H(+) + L-1-piperideine-6-carboxylate + NADH + NH4(+) => L-lysine + NAD(+)


name: 3 CO2 + 4 CoA + H2O + isoliquiritigenin + NADP(+) => 4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH


name: 2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = 2 H(+) + N(4)-bis(aminopropyl)spermidine + 2 S-methyl-5'-thioadenosine


name: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate <=> 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate


name: (3S)-hydroxy-(7Z-hexadecenoyl)-CoA => (2E,7Z)-hexadecadienoyl-CoA + H2O


name: MAPK4,6 translocate to nucleus (Caenorhabditis elegans)


name: Corticotropin cleavage from POMC (Sus scrofa)


name: (5R)-5-phosphooxy-L-lysine + H2O = (S)-2-amino-6-oxohexanoate + NH4(+) + phosphate


name: CFTR transports Cl- from cytosol to extracellular region (Rattus norvegicus)


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Rattus norvegicus)


name: RNA Pol II initiates transcription from damaged DNA template (Mus musculus)


name: adenosine 3',5'-bisphosphate + 2 H(+) + succinyl-4'-phosphopantetheine => H2O + succinyl-CoA


name: IRAK interacts with TRAF6 (Mus musculus)


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Homo sapiens)


name: SLC22A1 transports Cipro into renal cell (Danio rerio)


name: 6-sulfo-D-quinovose + NAD(+) => 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H(+) + NADH


name: Internal Methylation of mRNA (Gallus gallus)


name: AGRN binds Beta amyloid fibril via GAG chains (Bos taurus)


name: (3Z)-dodecenoyl-CoA + acetyl-CoA => 3-oxo-(5Z-tetradecenoyl)-CoA + CoA


name: cubebol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH


name: 5beta-androstane-3,17-dione + NADP(+) => androst-4-ene-3,17-dione + H(+) + NADPH


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O => (N(2),N(2),N(7))-trimethyl-GMP + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+)


name: di-trans,octa-cis-undecaprenyl diphosphate + H2O <=> di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate


name: (Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 => (-)-4'-methoxycyclopenine + CO2 + succinate


name: WNT5A-FZD4 recruits DVL2 (Caenorhabditis elegans)


name: an N-(fatty acyl)-L-asparagine + H2O => a fatty acid + L-asparagine


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Xenopus tropicalis)


name: Transport of MHC II:Ii complex along Golgi to TGN (Danio rerio)


name: Activated thrombin (factor IIa) cleaves PAR3,4, activating them (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: ATP + D-fructose(out) + H2O = ADP + D-fructose(in) + H(+) + phosphate


name: DHI and DHICA polymerize forming eumelanin (Sus scrofa)


name: Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Canis familiaris)


name: ATP-dependent H3-H4 histone complex chaperone activity


name: Activated FGFR3 phosphorylates FRS2 (Homo sapiens)


name: Activation of Rho by LARG and PDZ-RhoGEF (Canis familiaris)


name: ALDHs oxidise atRAL to atRA (Xenopus tropicalis)


name: Acetylcholine synaptic vesicle docking and priming (Bos taurus)


name: Binding of ERp57 (Schizosaccharomyces pombe)


name: RNA Polymerase III Abortive Initiation At Type 1 Open Promoters (Homo sapiens)


name: 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Saccharomyces cerevisiae)


name: UROD decarboxylates URO1 to COPRO1 (Dictyostelium discoideum)


name: 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate = 3-amino-4-hydroxybenzoate + H(+) + 2 H2O + phosphate


name: (2E)-geranial + H2O + NAD(+) = geranate + 2 H(+) + NADH


name: butanoate + dibutanoylglycerol + H(+) => 1,2,3-tributanoylglycerol + H2O


name: Defective SLC12A3 does not cotransport Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: AFG3L2 binds mitochondrial matrix proteins (Drosophila melanogaster)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] => 15alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Ethylene is oxidized to Ethylene oxide by CYP1A1 (Homo sapiens)


name: 4-O-phospho-D-threonate + NAD(+) => CO2 + dihydroxyacetone phosphate + NADH


name: H2O + L-alanyl-L-aspartate => L-alanine + L-aspartate


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Danio rerio)


name: ATR phosphorylates RPA2 (Caenorhabditis elegans)


name: ADP + H(+) + phosphocholine => ATP + choline


name: p-S158,221-HuR binds mRNA (Drosophila melanogaster)


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Sus scrofa)


name: (2E)-dodecenoyl-CoA + H2O2 => dodecanoyl-CoA + O2


name: (1S,4R)-isodihydrocarvone + H(+) + NADPH + O2 <=> (3S,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: 2,3-dihydroxy-3-methylbutanoate <=> 3-methyl-2-oxobutanoate + H2O


name: USP43 binds ISG:K164,ISG:K168-PCNA (Homo sapiens)


name: hexadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase] => AMP + H(+) + hexadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Homo sapiens)


name: 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O => 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA


name: 2-hydroxyhexadecanoyl-CoA + sphinganine => CoA + H(+) + N-(2-hydroxyhexadecanoyl)-sphinganine


name: GMP + methylglyoxal = N(2)-(1-hydroxy-2-oxopropyl)-GMP


name: GGCT transforms gGluCys to OPRO (Rattus norvegicus)


name: GST dimers conjugate GSH with cytosolic substrates (Xenopus tropicalis)


name: 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + 2 chloride + 2 H(+) => (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + 2 H2O


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: Activated FGFR3 phosphorylates FRS2 (Rattus norvegicus)


name: homogentisate + O2 => maleylacetoacetate (Danio rerio)


name: MMP14:TIMP2 binds proMMP2 (Rattus norvegicus)


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Mus musculus)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Drosophila melanogaster)


name: aldehyde dehydrogenase (quinone) activity


name: D-arabinose + pyruvate => 3-deoxy-alpha-D-manno-oct-2-ulosonate


name: CoA + NAD(+) + sulfoacetaldehyde => H(+) + NADH + sulfoacetyl-CoA


name: H(+) + L-glutamyl-[protein] + methanol => [protein]-L-glutamate 5-O-methyl ester + H2O


name: CX3 complex binds D-loop structures (Gallus gallus)


name: cholesteryl (9Z-octadecenoate) + H2O <=> (9Z)-octadecenoate + cholesterol + H(+)


name: all-trans-retinol + hexadecanoyl-CoA <=> all-trans-retinyl hexadecanoate + CoA


name: Vesicular inhibitory amino acid transport (Bos taurus)


name: The SMAD2/3:SMAD4 complex transfers to the nucleus (Bos taurus)


name: HIPK2 phosphorylates RUNX1 and EP300 (Homo sapiens)


name: Interaction of Tie2 and Grb2 (Danio rerio)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Rattus norvegicus)


name: tricarboxylic acid transmembrane transporter activity


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Schizosaccharomyces pombe)


name: ATP + hygromycin B => 4-O-phosphohygromycin B + ADP + H(+)


name: butanoyl-CoA + ethanol <=> CoA + ethyl butanoate


name: Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus (Homo sapiens)


name: TGFBR2 phosphorylates TGFBR1 (Caenorhabditis elegans)


name: ITPA dimer dephosphorylates RBV-TP to RBV-MP (Canis familiaris)


name: 6-chloro-D-tryptophan + FAD + 2 H2O => chloride + D-tryptophan + FADH2 + O2


name: PIAS1 SUMOylates THRB with SUMO1. (Rattus norvegicus)


name: hexanal + NADP(+) => (E)-hex-2-enal + H(+) + NADPH


name: RAF phosphorylates MAP2K dimer (Sus scrofa)


name: PKC phosphorylates ROBO3.1 (Canis familiaris)


name: 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin] => a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin]


name: 4-ethylphenol + NAD(+) => 4-hydroxystyrene + H(+) + NADH


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Canis familiaris)


name: chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex (Bos taurus)


name: 2-(3,5-dihydroxyphenyl)-2-oxoacetate + L-glutamate => (S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate


name: isovitexin + O2 => 3'-dehydroisovitexin + H2O2


name: ATP + glycyl-L-glutamate(out) + H2O => ADP + glycyl-L-glutamate(in) + H(+) + phosphate


name: IL3 stimulation induces Vav binding to Tec kinase (Rattus norvegicus)


name: (-)-lariciresinol + NADP(+) = (-)-pinoresinol + H(+) + NADPH


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Sus scrofa)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Bos taurus)


name: NADP(+) + scyllo-inositol <=> H(+) + NADPH + scyllo-inosose


name: S-adenosyl-L-methionine + taxifolin => H(+) + S-adenosyl-L-homocysteine + taxifolin 4'-methyl ether


name: SRC-1 bound to ARRB2 is not activated (Gallus gallus)


name: factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Gallus gallus)


name: p75NTR ICD signals to NF-kB (Gallus gallus)


name: 1-naphthaldehyde + H2O + O2 = 1-naphthoate + H(+) + H2O2


name: H(+) + NADPH + progesterone => 3beta-hydroxypregn-4-ene-20-one + NADP(+)


name: Cytosolic PLK1 translocates to the nucleus (Danio rerio)


name: TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) (Homo sapiens)


name: SeMet is converted to AdoSeMet by MAT (Xenopus tropicalis)


name: NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene (Homo sapiens)


name: (2E)-13-methyltetradecenoyl-CoA + H(+) + NADPH <=> isopentadecanoyl-CoA + NADP(+)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Drosophila melanogaster)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Bos taurus)


name: thromboxane B2(out) => thromboxane B2(in)


name: CDK and DDK associate with the Mcm10:pre-replicative complex (Bos taurus)


name: GBA2 hydrolyzes GlcCer (plasma membrane) (Rattus norvegicus)


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Rattus norvegicus)


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Homo sapiens)


name: 4-nitrocatechol + NADPH + O2 <=> 2-hydroxy-1,4-benzoquinone + H2O + NADP(+) + nitrite


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Canis familiaris)


name: MAP2K2 phosphorylates MAPK1 (Dictyostelium discoideum)


name: 2,2-dimethylsuccinate(out) + 3 Na(+)(out) = 2,2-dimethylsuccinate(in) + 3 Na(+)(in)


name: (E)-4-coumaroyl-AMP + diphosphate => (E)-4-coumarate + ATP + H(+)


name: Cargo-carrying vesicles bud from the TGN (Drosophila melanogaster)


name: (2Z,6E)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Homo sapiens)


name: Activation of proMMP9 by proteases (Sus scrofa)


name: USP10 deubiquitinates SNX3, CFTR (Rattus norvegicus)


name: 3-(4-hydroxyphenyl)pyruvate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tyrosine


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Sus scrofa)


name: 5-deoxy-D-ribose + ATP => 5-deoxy-alpha-D-ribose 1-phosphate + ADP + H(+)


name: H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu) => L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein]


name: O2 + reduced [NADPH--hemoprotein reductase] + tryptamine => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + serotonin


name: Syndecans 1, 2, 4, (3) bind FGF2 (Mus musculus)


name: XYLTs transfer Xyl to core protein (Rattus norvegicus)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Rattus norvegicus)


name: 10-oxooctadecanoate + NAD(+) => 10-oxo-(11E)-octadecenoate + H(+) + NADH


name: KSRP recruits RNA degradation activities (Bos taurus)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Dictyostelium discoideum)


name: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2 reduced [2Fe-2S]-[ferredoxin]


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Sus scrofa)


name: RNA demethylases demethylate N6-methyladenosine RNA (Danio rerio)


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ATP + H(+)(in) + H2O = ADP + 2 H(+)(out) + phosphate


name: L-phenylalanine(in) + L-valine(out) => L-phenylalanine(out) + L-valine(in)


name: Formation of MSH1:PMS2 Complex (Gallus gallus)


name: 6-dehydro-D-glucose + FMN + 2 H(+) + H2O + sulfite => 6-sulfo-D-quinovose + FMNH2 + O2


name: AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)


name: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + enolpyruvoyl-2-diphospho-5'-guanosine <=> dehydro coenzyme F420-0 + GMP + H(+)


name: 3,5-dimethylcyclohexanamine + H2O + NADP(+) => 3,5-dimethylcyclohexanone + H(+) + NADPH + NH4(+)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) <=> (6R)-5,10-methenyltetrahydrofolate + NADPH


name: Activated PKC phosphorylates SHC1 (Rattus norvegicus)


name: 3,4-dihydroxybenzoyl-5'-AMP + holo-[aryl-carrier protein] <=> 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + H(+)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Danio rerio)


name: trans-4-hydroxy-L-proline + ubiquinone-10 = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H(+) + ubiquinol-10


name: D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity


name: Caspase-mediated cleavage of MST3 (Bos taurus)


name: IRAK1 binds to MYD88 within the IL1R complex (Homo sapiens)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + H2O = 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H(+)


name: an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: IRAK1 induces oligomerisation of TRAF6 (Sus scrofa)


name: iron ion transmembrane transporter inhibitor activity


name: Cho is phosphorylated to PCho by CHK dimer (Schizosaccharomyces pombe)


name: a 2'-deoxyribonucleoside 5'-triphosphate + ADP => a 2'-deoxyribonucleoside 5'-diphosphate + ATP


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-choline = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: 2-aminocyclohexanol + H2O + NAD(+) = 2-hydroxycyclohexan-1-one + H(+) + NADH + NH4(+)


name: acetyl-CoA + N-terminal L-prolyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-prolyl-[protein]


name: gp130:JAKs bind CNTFR (Rattus norvegicus)


name: Monomeric PGN binds to PGRP-LE in the cytosol (Drosophila melanogaster)


name: NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix] (Danio rerio)


name: acetyl-CoA + succinyl-CoA = 3-oxoadipyl-CoA + CoA


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)


name: an aldopyranose + NAD(+) = aldono-1,5-lactone + H(+) + NADH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O


name: 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetyl-CoA


name: METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Xenopus tropicalis)


name: (R)-carnitine + tetradecanoyl-CoA => CoA + O-tetradecanoyl-(R)-carnitine


name: Disassociation of PLC-gamma1 from SLP-76 (Sus scrofa)


name: LMCD1 binds GATA6, sequestering it (Sus scrofa)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Saccharomyces cerevisiae)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Plasmodium falciparum)


name: ethyl (S)-3-hydroxyhexanoate + NADP(+) => ethyl 3-oxohexanoate + H(+) + NADPH


name: P2X7 mediates loss of intracellular K+ (Sus scrofa)


name: L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine <=> 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-methyl-5'-thioadenosine


name: Defective OPN1SW causes tritanopia (Homo sapiens)


name: L-glutamine + scyllo-inosose <=> 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate


name: 8-amino-8-demethylriboflavin + 2 S-adenosyl-L-methionine <=> 2 H(+) + roseoflavin + 2 S-adenosyl-L-homocysteine


name: Displacement of UNG glycosylase by APEX1 at the AP site (Homo sapiens)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Schizosaccharomyces pombe)


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Schizosaccharomyces pombe)


name: TXLNA (IL14) binds syntaxin3 (Bos taurus)


name: T1R1/T1R3 dimer is the umami taste receptor (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: carbamoyl phosphate + ornithine => citrulline + orthophosphate (Saccharomyces cerevisiae)


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Mus musculus)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Danio rerio)


name: 1-acyl-2-(9Z)-enoyl-sn-glycero-3-phospholipid + S-adenosyl-L-methionine <=> 1-acyl-2-(10-methylene)-acyl-sn-glycero-3-phospholipid + H(+) + S-adenosyl-L-homocysteine


name: a very long-chain fatty acid(in) + ATP + H2O => a very long-chain fatty acid(out) + ADP + H(+) + phosphate


name: (2R,3S)-2,4',7-trihydroxyisoflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-liquiritigenin + O2 + reduced [NADPH--hemoprotein reductase]


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Mus musculus)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Homo sapiens)


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH <=> a long-chain fatty acyl-CoA + n CO2 + n CoA + H2O + 2n NADP(+)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Caenorhabditis elegans)


name: an L-N,N-dihydroxypolyhomomethionine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => an L-N-hydroxypolyhomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: Orexin 1 receptor can bind orexin-A neuropeptide (Mus musculus)


name: p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP (Rattus norvegicus)


name: DSB inducing agents induce double strand DNA breaks (Homo sapiens)


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Drosophila melanogaster)


name: RAS GEFs promote RAS nucleotide exchange (Homo sapiens)


name: Defective IDS does not hydrolyse Heparan sulfate chain(5) (Homo sapiens)


name: IL2RA (CD25) gene expression is stimulated by FOXP3 and inhibited by RUNX1 (Homo sapiens)


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Danio rerio)


name: (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + AH2 => (R)-2-hydroxy-(9Z,12Z,15Z)-octadecatrienoate + A + H2O


name: Further sulfation on galactose residues produces KSPG (Drosophila melanogaster)


name: secondary active monocarboxylate transmembrane transporter activity


name: SIRT1,SIRT3 deacetylate FOXO3 (Bos taurus)


name: 2 a 1,4-benzosemiquinone + NADP(+) => 2 a quinone + H(+) + NADPH


name: a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + AMP + H(+) => a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + GTP


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Gallus gallus)


name: 2 H(+) + hexadecanoyl-CoA + malonyl-CoA + methylmalonyl-CoA = 4-hydroxy-5-methyl-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA


name: Ubiquitinated geminin is degraded by the proteasome (Homo sapiens)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Sus scrofa)


name: HuR binds mRNAs in the nucleus (Xenopus tropicalis)


name: NR1H2,3 binds the ABCG5 gene (Homo sapiens)


name: SALM1 binds NMDA receptor (Homo sapiens)


name: [sulfur carrier]-SH + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + S-adenosyl-L-methionine => [sulfur carrier]-H + H(+) + L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => 1-hexadecanoyl-sn-glycero-3-phosphocholine + 10-hydroperoxy-(8E)-octadecenoate + H(+)


name: CI activates transcription (Drosophila melanogaster)


name: TRIM33 monoubiquitinates SMAD4 (Bos taurus)


name: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Bos taurus)


name: RUNX2 binds SMAD1 in the nucleus (Drosophila melanogaster)


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Gallus gallus)


name: dimethyl selenide methyltransferase activity


name: Me2Se is methylated to Me3Se+ by INMT (Homo sapiens)


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Sus scrofa)


name: Succinate <=> Fumarate (with FAD redox reaction on enzyme) (Schizosaccharomyces pombe)


name: (S)-propane-1,2-diol + NAD(+) => H(+) + hydroxyacetone + NADH


name: an N-acylsphing-4-enine 1-phosphate + choline + H(+) => a sphingomyelin + H2O


name: GLP1R binds GLP1R agonists (Homo sapiens)


name: CoA + glutathione disulfide <=> CoA-glutathione + glutathione


name: VEGFR2 autophosphorylates (Canis familiaris)


name: Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Mus musculus)


name: HSF1 trimer translocates to the nucleus (Drosophila melanogaster)


name: 22-oxodocosanoate + O2 + reduced [NADPH--hemoprotein reductase] => docosanedioate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of Elongin BC complex (Homo sapiens)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Drosophila melanogaster)


name: MATEs mediate extrusion of xenobiotics (Gallus gallus)


name: a 2,3-saturated meromycolyl-[ACP] + NAD(+) => a trans-Delta(2)-meromycolyl-[ACP] + H(+) + NADH


name: ADP + D-glyceraldehyde 3-phosphate + H(+) => ATP + D-glyceraldehyde


name: HTRA2 degrades NDUFA13 (GRIM-19) (Mus musculus)


name: 3-sulfanyl-2-(sulfanylmethyl)propanoate + NAD(+) => asparagusate + H(+) + NADH


name: IRE1 binds IRE1 forming dimer (Dictyostelium discoideum)


name: Formation of lysyl-pyrrole cross-links (Caenorhabditis elegans)


name: a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Activation of Rap1 by cytosolic GEFs (Bos taurus)


name: PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)


name: an N-acylethanolamine + H(+) + sn-glycerol 3-phosphate => H2O + N-acyl-sn-glycero-3-phosphoethanolamine


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Rattus norvegicus)


name: XDH oxidizes xanthine to form urate (Xenopus tropicalis)


name: STAT1,STAT3,STAT6 bind IL13:IL13R type II (Bos taurus)


name: dihydroferuloyl-CoA + NADP(+) <=> (E)-feruloyl-CoA + H(+) + NADPH


name: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) <=> H(+) + NADH + phenanthrene-3,4-diol


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Drosophila melanogaster)


name: an inositol-1-phosphophytoceramide + beta-D-mannose <=> a mannosylinositol-1-phosphophytoceramide + H2O


name: H(+) + indan-1-one + NADH => (S)-indan-1-ol + NAD(+)


name: KIT mutants bind type II TKIs (Homo sapiens)


name: Phosphorylation of TEC kinases by p-SYK (Mus musculus)


name: Release of SMAC (DIABLO) from mitochondria (Rattus norvegicus)


name: pre-sodorifen diphosphate = diphosphate + sodorifen


name: 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol <=> calcitetrol + H2O + 2 oxidized [adrenodoxin]


name: 6'-oxoparomamine + L-glutamate => 2-oxoglutarate + neamine


name: 2-methylhexadecanoate + ATP + CoA => 2-methylhexadecanoyl-CoA + AMP + diphosphate


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP


name: APOM binds retinoids (Xenopus tropicalis)


name: 2 ATP + 2 H(+) => H2O + P(1),P(6)-bis(5'-adenosyl) hexaphosphate


name: a thymidine(6-4)thymidine in DNA <=> a thymidine dimer in DNA


name: Acireductone is oxidized to MOB (Drosophila melanogaster)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Gallus gallus)


name: ent-copalyl diphosphate <=> (Z)-biformene + diphosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + a 1-acyl-sn-glycero-3-phosphoethanolamine + H(+) => 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O


name: SLC19A2/3 transport extracellular THMN to cytosol (Canis familiaris)


name: (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine <=> 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Mus musculus)


name: SGK1 phosphorylates MDM2 (Gallus gallus)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 2 A + 3 H2O <=> [DsrC protein]-dithiol + 2 AH2 + 2 H(+) + sulfite


name: 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] + H(+) + NADH + O2 = 3,5-dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + H2O + NAD(+)


name: DUS2 binds PKR (Drosophila melanogaster)


name: (9Z,12Z)-octadecadienoate + O2 <=> (13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: acetoin + NADP(+) = diacetyl + H(+) + NADPH


name: Extension of pseudopodia by myosin-X in a PI3K dependent manner (Rattus norvegicus)


name: (2E)-3-(3-hydroxyphenyl)prop-2-enoate + H(+) + NADH + O2 <=> (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD(+)


name: N,N',N'',N'''-tetraacetylchitotetraose + O2 <=> H2O2 + N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone


name: 2 Fe(III)-[leghemoglobin] + NADH = 2 Fe(II)-[leghemoglobin] + H(+) + NAD(+)


name: AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Xenopus tropicalis)


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2 => (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2


name: gamma-tocopherol + S-adenosyl-L-methionine = (+)-alpha-tocopherol + H(+) + S-adenosyl-L-homocysteine


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Dictyostelium discoideum)


name: PTK2 is recruited to methylated ESR1 (Mus musculus)


name: Complement factor I binds to extracellular Factor H:C3b (Homo sapiens)


name: H(+) + kaempferol 3-O-beta-D-xyloside + UDP => kaempferol + UDP-alpha-D-xylose


name: high-affinity L-histidine transmembrane transporter activity


name: 3-hydroxybutane-1,2,3-tricarboxylate <=> pyruvate + succinate


name: 5,6-dihydrouridine(20) in tRNA + NADP(+) = H(+) + NADPH + uridine(20) in tRNA


name: H2O + UDP-4-dehydro-6-deoxy-alpha-D-glucose => UDP-alpha-D-glucose


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Bos taurus)


name: SUMOylation of NR3C1 (GR) with SUMO1 (Bos taurus)


name: A + 2 cob(II)alamin + 2 H(+) + 2 H2O => AH2 + 2 aquacob(III)alamin


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Drosophila melanogaster)


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Canis familiaris)


name: YWHAB dimer dissociates from dephosphorylated RAF (Sus scrofa)


name: H(+) + myricetin 3-O-alpha-L-rhamnoside + UDP => myricetin + UDP-beta-L-rhamnose


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Rattus norvegicus)


name: H(+)(out) + L-galactose(out) <=> H(+)(in) + L-galactose(in)


name: a ganglioside GM3 (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetylneuraminate


name: (2S)-hesperidin + H2O = (2S)-hesperetin + rutinose


name: a 2-acylglycerol + H2O <=> a carboxylate + glycerol + H(+)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Mus musculus)


name: PAK phosphorylates cortactin (Homo sapiens)


name: 2-oxobutanoate + H(+) + NADH + NH4(+) => (2S)-2-aminobutanoate + H2O + NAD(+)


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA <=> an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA + holo-[ACP]


name: 2 Na(+)(in) + tauroallocholate(in) => 2 Na(+)(out) + tauroallocholate(out)


name: Furin cleaves pro-factor IX to factor IX (Danio rerio)


name: Prolactin-releasing hormone receptor binds PRH (Rattus norvegicus)


name: TFRC dimer binds 2xholoTF (Rattus norvegicus)


name: USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Canis familiaris)


name: ACER2 hydrolyzes ceramide (Golgi) (Drosophila melanogaster)


name: glycine + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoylglycine


name: ATP + GTP <=> 2',3'-cGAMP + 2 diphosphate


name: 2-methylmaleate + H2O = (2R,3S)-3-methylmalate


name: DNMT3B:DNMT3L binds chromatin (Homo sapiens)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Sus scrofa)


name: RHOF GAPs stimulate RHOF GTPase activity (Drosophila melanogaster)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Interaction of Tie2 and p85 of PI3K (Canis familiaris)


name: DNA polymerase delta polymerizes DNA across single stranded gap (Canis familiaris)


name: TMEM55B translocates to the nucleus (Danio rerio)


name: (4S)-4-hydroxy-L-glutamate + 2 H(+) + NADH => H2O + L-4-hydroxyglutamate semialdehyde + NAD(+)


name: Formation of PRC2-EZH2 complex (Bos taurus)


name: 5-deoxy-alpha-D-ribose 1-phosphate = 5-deoxy-D-ribulose 1-phosphate


name: ALDH8A1 oxidises 9cRAL to 9cRA (Sus scrofa)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol (Homo sapiens)


name: a uridine in 21S rRNA + S-adenosyl-L-methionine => a 2'-O-methyluridine in 21S rRNA + H(+) + S-adenosyl-L-homocysteine


name: p-Y701-STAT1 binds p-Y705-STAT3 (Bos taurus)


name: 4-hydroxybenzoyl-CoA + H2O => 4-hydroxybenzoate + CoA + H(+)


name: 4-hydroxyhexan-3-amine + H2O + NAD(+) = 4-hydroxyhexan-3-one + H(+) + NADH + NH4(+)


name: norbelladine + S-adenosyl-L-methionine <=> 4'-O-methylnorbelladine + H(+) + S-adenosyl-L-homocysteine


name: FOXA1 and GATA3 bind to CCND1 promoter (Sus scrofa)


name: CBFB binds RUNX3 (Drosophila melanogaster)


name: CBP and p300 binds NF-kB complex (Canis familiaris)


name: L-phenylalanine(out) + L-valine(in) <=> L-phenylalanine(in) + L-valine(out)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + 2 S-adenosyl-L-homocysteine => a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Mus musculus)


name: 2-oxoglutarate + 4-aminobutanoate = L-glutamate + succinate semialdehyde


name: epothilone C + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = epothilone A + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: diphosphate + sabinene => (2E)-geranyl diphosphate


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 <=> (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2


name: 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: H2O + sucrose = alpha-D-glucose + beta-D-fructose


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Bos taurus)


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Homo sapiens)


name: H2O2 + tetradecanoate => (2R)-hydroxytetradecanoate + H2O


name: 3-(2-aminophenyl)-3-oxopropanal + H2O2 + NH4(+) => H2O + kynuramine + O2


name: IGF1,2:IGF1R autophosphorylates (Sus scrofa)


name: 8-oxo-GDP + H2O <=> 8-oxo-GMP + H(+) + phosphate


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Bos taurus)


name: p75NTR and RHOA-GDI interact (Canis familiaris)


name: estrone 3-sulfate(out) + 2 Na(+)(out) <=> estrone 3-sulfate(in) + 2 Na(+)(in)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Canis familiaris)


name: ATP + thiamine diphosphate = ADP + thiamine triphosphate


name: 4-aminobutanal + H2O + NAD(+) => 4-aminobutanoate + 2 H(+) + NADH


name: Syk/Lck phosphorylate LAT (Canis familiaris)


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Sus scrofa)


name: 2-chloro-6-hydroxy-1,4-benzoquinone + chloride + 2 H(+) => 2,6-dichlorobenzoquinone + H2O


name: A + H2O + NH4(+) <=> AH2 + H(+) + hydroxylamine


name: Insertion of MHC II:Ii complex in to the plasma membrane (Bos taurus)


name: hexadecan-1-ol + NAD(+) => H(+) + hexadecanal + NADH


name: RAC1 and CDC42 activate PAK3 (Caenorhabditis elegans)


name: EML4 recruits NUDC to mitotic spindle (Mus musculus)


name: phosphate + RNA(n+1) <=> a ribonucleoside 5'-diphosphate + RNA(n)


name: 6-phospho-D-gluconate + NAD(+) => 6-phospho-2-dehydro-D-gluconate + H(+) + NADH


name: ACER2 hydrolyzes ceramide (Golgi) (Xenopus tropicalis)


name: H2O + imidazol-4-one => N-formimidoylglycine


name: glycine(in) + L-phenylalanine(out) <=> glycine(out) + L-phenylalanine(in)


name: CYP2C19 5-hydroxylates omeprazole (Drosophila melanogaster)


name: acetyl-CoA + L-leucine <=> CoA + H(+) + N-acetyl-L-leucine


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Mus musculus)


name: Activated MET binds GAB1 (Rattus norvegicus)


name: glutamate dehydrogenase (NADP+) activity


name: SGTA binds Tail-anchored protein (Schizosaccharomyces pombe)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: SEMA4D interacts with CD72 (Gallus gallus)


name: L-kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine


name: 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate](n) <=> adenosine 3',5'-bisphosphate + 2 H(+) + N-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n)


name: Interaction of SHP-1 or SHP-2 with phospho PD-1 (Bos taurus)


name: BCL2 binds BCL2 antagonists (Gallus gallus)


name: GLI2 is degraded by the proteasome (Homo sapiens)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Danio rerio)


name: (E)-sinapyl alcohol + acetyl-CoA = (E)-sinapoyl actetate + CoA


name: GLUT7 and GLUT11 transport glucose and fructose (Canis familiaris)


name: cyclin-dependent protein kinase activity


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Plasmodium falciparum)


name: Active ARF recruits coatomer (Mus musculus)


name: Formation of the MCC complex (Homo sapiens)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Canis familiaris)


name: POLZ elongates POLI-incorporated dNMP (Homo sapiens)


name: 3 a ubiquinol + protoporphyrin IX => 3 a ubiquinone + protoporphyrinogen IX


name: 2 3-phenylpyruvate + H(+) <=> H2O + phenguignardate


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Bos taurus)


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Sus scrofa)


name: FECH binds Fe2+ to PRIN9 to form heme (Drosophila melanogaster)


name: chloride + D-tryptophan + FADH2 + O2 => 6-chloro-D-tryptophan + FAD + 2 H2O


name: 3beta,7beta-dihydroxy-5alpha-androstan-17-one + NADP(+) => 3beta-hydroxy-5alpha-androstane-7,17-dione + H(+) + NADPH


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Gallus gallus)


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Xenopus tropicalis)


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Mus musculus)


name: 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O => 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-threonyl-[protein] + H(+) + UDP


name: CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Drosophila melanogaster)


name: ATP + shikimate <=> 3-phosphoshikimate + ADP + H(+)


name: RHOA GAPs stimulate RHOA GTPase activity (Danio rerio)


name: a uridine in 12S rRNA + S-adenosyl-L-methionine = a 5-methyluridine in 12S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O => 5alpha-cholestane-3beta,5,6beta-triol


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Mus musculus)


name: (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA = (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H2O


name: Dephosphorylation of JAK1 by SHP1 (Mus musculus)


name: decanoate-[HmqF protein] ligase activity


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 4-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: eNoSC dimethylates histone H3 at lysine-9 (Canis familiaris)


name: H2O + L-seryl-tRNA(Lys) = L-serine + tRNA(Lys)


name: CDC42 GEFs activate CDC42 (Saccharomyces cerevisiae)


name: (R)-carnitine + dodecanoyl-CoA => CoA + O-dodecanoyl-R-carnitine


name: PIAS2-2 SUMOylates THRA with SUMO1 (Gallus gallus)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Xenopus tropicalis)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Bos taurus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine => 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine


name: PC catalyzes the carboxylation of PYR to form OA (Bos taurus)


name: acetyl-CoA + CO2 + NADH => 3-oxopropanoate + CoA + NAD(+)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Dictyostelium discoideum)


name: Transport of VPU to Golgi apparatus (Homo sapiens)


name: PAO:FAD oxidises NASPM to PTCN (Rattus norvegicus)


name: AH2 + androst-4-ene-3,17-dione + O2 => A + H2O + testololactone


name: MVD decarboxylates MVA5PP to IPPP (Saccharomyces cerevisiae)


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Saccharomyces cerevisiae)


name: (9Z,12Z)-octadecadienoate + O2 <=> (2R,9Z,12Z)-2-hydroperoxyoctadecadienoate


name: ALK-stimulated MYCN gene expression (Homo sapiens)


name: 7-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: (2E,11Z)-eicosadienoyl-CoA + H(+) + NADPH <=> (11Z)-eicosenoyl-CoA + NADP(+)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Homo sapiens)


name: CBL recruits CIN85:endophilin to ubiquitinated MET (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: (9Z)-octadecenoyl-CoA + dopamine = CoA + H(+) + N-(9Z-octadecanoyl)-dopamine


name: estrone + H(+) + NADPH => 17alpha-estradiol + NADP(+)


name: campesterol + UDP-alpha-D-glucose = campesteryl 3-beta-D-glucoside + H(+) + UDP


name: 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H2O = (9Z)-octadecenoate + 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H(+)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: "linoleoyl-lipid Delta(12) conjugase (11E,13Z-forming)"


name: H2O + substance P => L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-6)


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Mus musculus)


name: hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ (Gallus gallus)


name: N-acetyl-D-glucosamine + O2 = H2O2 + N-acetyl-D-glucosamino-1,5-lactone


name: Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box (Homo sapiens)


name: RNA polymerase II CTD heptapeptide repeat T4 kinase activity


name: POLZ elongates POLI-incorporated dNMP (Drosophila melanogaster)


name: 28-norteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 6alpha-hydroxy-28-norteasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: tomatidine + UDP-alpha-D-glucose = H(+) + tomatidine 3-O-beta-D-glucopyranoside + UDP


name: ADP + D-glucose 6-phosphate + H(+) => ATP + D-glucose


name: Ficolin-1 binds to molecular patterns on the target cell surface (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acylsphing-4-enine <=> a 1,2-diacyl-sn-glycerol + an N-acylsphing-4-enine-(1D-myo-inositol)


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: NCOA2(869-1464) binds KAT6A(1-1118) (Danio rerio)


name: Proteasome mediated degradation of Cyclin D1 (Danio rerio)


name: BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Canis familiaris)


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)


name: ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate => ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate


name: p-S256-Aquaporin-2 passively transports water into cell (Drosophila melanogaster)


name: CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonate + diphosphate => 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + CTP


name: L-ascorbate + O2 + tyramine <=> (R)-octopamine + H2O + L-dehydroascorbate


name: ATP + H(+) + NADPH + nonanoate <=> AMP + diphosphate + NADP(+) + nonanal


name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity


name: (2S)-2-nitrosobutanedioate + H(+) + NADPH + O2 = 2-nitrobutanedioate + H2O + NADP(+)


name: Release of eIF4E from the inactive eIF4E:4E-BP complex  (Gallus gallus)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Mus musculus)


name: N-acetylglucosamine transmembrane transporter activity


name: NADP(+) + scyllo-inositol = H(+) + NADPH + scyllo-inosose


name: RAC3 GAPs stimulate RAC3 GTPase activity (Sus scrofa)


name: Rheb in the MTORC1 complex hydrolyses GTP (Canis familiaris)


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Caenorhabditis elegans)


name: TRAF3 binds to TRIF:activated TLR3 complex (Homo sapiens)


name: 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide] => an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide]


name: 3-dehydro-D-erythronate + H(+) + NADH => L-threonate + NAD(+)


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Mus musculus)


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-8-hydroperoxy-20-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: NCEH1 hydrolyzes cholesterol esters (Mus musculus)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Danio rerio)


name: ATP + methylphosphonate => adenine + alpha-D-ribose 1-methylphosphonate 5-triphosphate


name: D-maltose + H2O = alpha-D-glucose + D-glucose


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: acetylsalicylate + L-lysyl-[protein] = H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate


name: (R)-laudanine + H(+) + S-adenosyl-L-homocysteine => (R)-reticuline + S-adenosyl-L-methionine


name: (2E,6E)-farnesyl diphosphate + H2O = (5S,9S,10S)-drim-7-en-11-ol + diphosphate


name: H2O + N-acetyl-L-glutamine => acetate + L-glutamine


name: Diacylgycerol activates Protein kinase C, alpha type (Dictyostelium discoideum)


name: a long-chain fatty acyl-CoA + n CO2 + n CoA + H2O + 2n NADP(+) => acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH


name: Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Gallus gallus)


name: eukaryotic elongation factor-2 kinase regulator activity


name: Formation of the CE:GMP intermediate complex (Canis familiaris)


name: 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + O2 => a 2'-deoxyadenosine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: TXLNA (IL14) binds syntaxin1A (Bos taurus)


name: 8-carboxy-8-demethylriboflavin 5'-phosphate + 2 A + H2O + L-glutamate <=> 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 2 AH2 + CO2


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Canis familiaris)


name: (E)-ferulate + glycine => H2O + N-feruloylglycine


name: ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA (Homo sapiens)


name: thromboxane B2(out) <=> thromboxane B2(in)


name: 3-dehydrocarnityl-CoA + acetate => 3-dehydrocarnitine + acetyl-CoA


name: (R)-carnitine(out) + 2-oxoglutarate(in) <=> (R)-carnitine(in) + 2-oxoglutarate(out)


name: 1,2,3-trioctanoylglycerol + H2O = 1,2-dioctanoyl-sn-glycerol + H(+) + octanoate


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Dictyostelium discoideum)


name: sucrose + UDP-alpha-D-galactose <=> 6(F)-alpha-D-galactosylsucrose + H(+) + UDP


name: choline(in) + H(+)(in) <=> choline(out) + H(+)(out)


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + NAD(+) => 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + H(+) + NADH


name: Catabolism of Noradrenaline (Mus musculus)


name: 2-hexadecenoyl-sn-glycero-3-phosphate + a fatty acid + H(+) => 1-acyl-2-hexadecenoyl-sn-glycero-3-phosphate + H2O


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Mus musculus)


name: NAD(+) + propanoyl-CoA <=> acryloyl-CoA + H(+) + NADH


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine


name: glycerol + H(+) + prostaglandin F2alpha => H2O + prostaglandin F2alpha 1-glyceryl ester


name: (3R)-hydroxy-(5Z)-dodecenoyl-[ACP] = (2E,5Z)-dodecadienoyl-[ACP] + H2O


name: TGM1 and involucrin bind the plasma membrane (Homo sapiens)


name: Dimethyl fumarate modifies Cys191 in GSDMD (Sus scrofa)


name: androst-5-en-3beta,17beta-diol + NAD(+) => 17beta-hydroxy-androst-5-en-3-one + H(+) + NADH


name: a quinone + H2O + selenite = a quinol + selenate


name: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O = (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H(+)


name: 2 formate + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 CO2 + H(+) + NADH + 2 reduced [2Fe-2S]-[ferredoxin]


name: "formate dehydrogenase (NAD(+), ferredoxin)"


name: a ganglioside GT1a + CMP + H(+) => a ganglioside GD1a + CMP-N-acetyl-beta-neuraminate


name: 5 H(+)(in) + NADH + ubiquinone-8 <=> 4 H(+)(out) + NAD(+) + ubiquinol-8


name: light-driven active monoatomic ion transmembrane transporter activity


name: a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+) => a 2'-deoxyribonucleoside 5'-triphosphate + H2O


name: GDIs block activation of RHOC (Homo sapiens)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha,13alpha-diol => O2 + reduced [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha-ol


name: CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP (Homo sapiens)


name: 3-hydroxyphenylacetate + H(+) + NADPH + O2 => H2O + homogentisate + NADP(+)


name: AMP + ATP <=> ADP + ADP [AK2] (Xenopus tropicalis)


name: ALDH7A1 oxidises BETALD to BET (Bos taurus)


name: PARG dePARylates PARP1,PARP2 (Xenopus tropicalis)


name: mogrol + UDP-alpha-D-glucose => H(+) + mogroside IE + UDP


name: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnose + H2O = 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose


name: 3-oxoeicosasphinganine + H(+) + NADPH => C20 sphinganine + NADP(+)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] = 1,4-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MAP3K8 is phosphorylated (Gallus gallus)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Dictyostelium discoideum)


name: a medium chain fatty acid + ATP + holo-[ACP] = a medium-chain fatty acyl-[ACP] + AMP + diphosphate


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)


name: (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + O2 => (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-oxazole-[protein] + H2O2


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O <=> 1,2-diacyl-sn-glycero-3-phospho-L-serine-N-glycine + [protein]-C-terminal <stereo>L-</stereo>amino acid


name: 8-methylmenaquinol-6 + fumarate => 8-methylmenaquinone-6 + succinate


name: (10E,12Z)-octadecadienoate + H2O => (10S)-hydroxy-(12Z)-octadecenoate


name: a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+)


name: (2E)-decenoyl-CoA + H2O => 3-hydroxydecanoyl-CoA


name: MHC class II antigen processing (Canis familiaris)


name: ATP(in) + dATP(out) => ATP(out) + dATP(in)


name: C5a anaphylatoxin binds C5a receptor (Gallus gallus)


name: 9alpha-copalyl diphosphate => 9beta-pimara-7,15-diene + diphosphate


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Homo sapiens)


name: TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 (Homo sapiens)


name: Phosphorylation of LIMK-1 by PAK (Drosophila melanogaster)


name: (20S)-protopanaxadiol + O2 + reduced [NADPH--hemoprotein reductase] <=> (20S)-protopanaxatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 11-methyldodecanoyl-CoA + H(+) + malonyl-CoA => 3-oxoisopentadecanoyl-CoA + CO2 + CoA


name: deoxycohumulone + diphosphate => 4-prenylphlorisobutanophenone + dimethylallyl diphosphate


name: RHOF binds effectors at the plasma membrane (Caenorhabditis elegans)


name: D-glucose 6-phosphate(in) + phosphate(out) <=> D-glucose 6-phosphate(out) + phosphate(in)


name: MME:Zn2+ binds sacubitrilat (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-corvol ether B + diphosphate


name: HDHD1:Mg2+ dephosphorylates PURIDP (Canis familiaris)


name: geranylgeranyl diphosphate <=> tuberculosinyl diphosphate


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Mus musculus)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Xenopus tropicalis)


name: urocanate + H2O => 4-imidazolone-5-propionate (Sus scrofa)


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Bos taurus)


name: H2O + N-(4-oxoglutaryl)-L-cysteinylglycine = 2-oxoglutarate + L-cysteinylglycine


name: SARS-CoV-1 M binds to PDPK1 (Homo sapiens)


name: IKK complex is activated by PKR (Sus scrofa)


name: S-adenosyl-L-methionine + uridine in 25S rRNA <=> H(+) + N(3)-methyluridine in 25S rRNA + S-adenosyl-L-homocysteine


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Xenopus tropicalis)


name: PDGF-AB clevage by Furin (Gallus gallus)


name: Phosphorylation of YAP by LATS1 (Gallus gallus)


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Sus scrofa)


name: SMG6 hydrolyzes mRNA with premature termination codon (Xenopus tropicalis)


name: Neurotensin receptors can bind neurotensins (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a monoacyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate => (9Z,12Z)-octadecadienoate + O2


name: 13-deoxydaunorubicin + H(+) + NADPH + O2 <=> 13-dihydrodaunorubicin + H2O + NADP(+)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Dictyostelium discoideum)


name: maleylacetoacetate => fumarylacetoacetate (Rattus norvegicus)


name: SHC1 bound to IL2 receptor is phosphorylated (Homo sapiens)


name: a cytidine in rRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: phosphatidylinositol 3-kinase catalytic subunit binding


name: PTK6 phosphorylates ARHGAP35 (Bos taurus)


name: NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Homo sapiens)


name: Association of Securin with Cdc20:APC/C complex (Gallus gallus)


name: H2O + S-3-(hexan-1-ol)-L-cysteine => 3-sulfanyl-1-hexanol + NH4(+) + pyruvate


name: (2Z,6Z)-farnesyl diphosphate => (E)-beta-farnesene + diphosphate


name: a lactoside III(4)-a-Fuc-Lc4Cer + GDP + H(+) => GDP-beta-L-fucose + Lc4Cer


name: Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Canis familiaris)


name: a lipid A disaccharide + ATP => a lipid IVA + ADP + H(+)


name: 2-dehydro-3-deoxy-D-gluconate + NH4(+) => (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O


name: Caspase-8 cleaves IL1B precursor (Sus scrofa)


name: 13-cis-retinyl hexadecanoate + CoA => 13-cis-retinol + hexadecanoyl-CoA


name: H(+)(in) + L-threonine(in) = H(+)(out) + L-threonine(out)


name: a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+)


name: 3-dehydro-6alpha-hydroxyteasterone + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydroteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome (Canis familiaris)


name: 2-(3-methylsulfanyl)propylmalate <=> 2-(2-methylsulfanyl)propylmaleate + H2O


name: OPLAH hydrolyses OPRO to L-Glu (Dictyostelium discoideum)


name: 3-sulfopyruvate + H(+) => CO2 + sulfoacetaldehyde


name: RUNX3 binds the NOTCH1 coactivator complex (Homo sapiens)


name: IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Sus scrofa)


name: 2 H(+) + O2 + rifamycin B => H2O2 + rifamycin O


name: cyclohexylamine + H2O + O2 => cyclohexanone + H2O2 + NH4(+)


name: Active FLT3:GRB2 binds SOS1 (Bos taurus)


name: D-maltobiono-1,5-lactone + H2O => D-maltobionate + H(+)


name: FDPS dimer transfers IPPP to DMAPP (Danio rerio)


name: H(+) + NADP(+) + 2 reduced [rubredoxin] <=> NADPH + 2 oxidized [rubredoxin]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoylglycerone 3-phosphate = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerone 3-phosphate + hexadecanoate


name: Formation of the closed pre-initiation complex (Mus musculus)


name: Abortive termination of HIV-1 early transcription elongation by DSIF:NELF (Homo sapiens)


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + acetyl-CoA <=> 1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: Phosphorylated GAB1 recruits PI3K to MET (Rattus norvegicus)


name: 12,13-dihydroxy-(9Z)-octadecenoate => 12,13-epoxy-(9Z)-octadecenoate + H2O


name: Insertion of MHC II:Ii complex in to the plasma membrane (Canis familiaris)


name: TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9. (Homo sapiens)


name: RPE dimers isomerise RU5P to XY5P (Schizosaccharomyces pombe)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Dictyostelium discoideum)


name: 16alpha,17beta-estriol + UDP-alpha-D-glucuronate => 16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + H(+) + UDP


name: ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol (Homo sapiens)


name: GGPS1 hexamer transfers IPPP to DMAPP (Sus scrofa)


name: Caspase-mediated cleavage of Acinus (Caenorhabditis elegans)


name: The Ligand:GPCR:G12/13 complex dissociates (Caenorhabditis elegans)


name: VAV1 is a GEF for Rho/Rac family GTPases (Caenorhabditis elegans)


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Homo sapiens)


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Sus scrofa)


name: Reversal of Alkylation Damage By DNA Dioxygenases (Gallus gallus)


name: Formation of the Flap Intermediate (Saccharomyces cerevisiae)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Xenopus tropicalis)


name: LDHAL6B reduces PYR to LACT (Mus musculus)


name: a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate <=> a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose 6-phosphate + H(+)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Xenopus tropicalis)


name: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid (Gallus gallus)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Gallus gallus)


name: cytidine(1920) in 23S rRNA + S-adenosyl-L-methionine => 2'-O-methylcytidine(1920) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Na(+)(out) + propanoate(out) => Na(+)(in) + propanoate(in)


name: Autoglucosylation of GYG1 complexed with GYS1-b (Homo sapiens)


name: AMP + diphosphate + L-glutamyl-tRNA(Glu) => ATP + L-glutamate + tRNA(Glu)


name: p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor (Canis familiaris)


name: Formation of the RBBP5:ASH2L heterodimer (Canis familiaris)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Dictyostelium discoideum)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA = 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O <=> beta-eudesmol + diphosphate


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Mus musculus)


name: 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate => beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O


name: NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Bos taurus)


name: Recruitment of SHC1 is mediated by Y593 of the common beta chain (Rattus norvegicus)


name: ATP + glutathione(in) + glycocholate(in) + H2O => ADP + glutathione(out) + glycocholate(out) + H(+) + phosphate


name: ubiquitin-protein transferase regulator activity


name: adenosine 3',5'-bisphosphate + H(+) + quercetin 3-sulfate => 3'-phosphoadenylyl sulfate + quercetin


name: histone H2B conserved C-terminal lysine deubiquitinase activity


name: a secondary alcohol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) => a ketone + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Association of procollagen type XIII (Canis familiaris)


name: 3-oxoisoheptadecanoyl-CoA + CO2 + CoA => H(+) + isopentadecanoyl-CoA + malonyl-CoA


name: Formation of Elongin BC complex (Xenopus tropicalis)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Rattus norvegicus)


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Caenorhabditis elegans)


name: RAF phosphorylates MAP2K dimer (Rattus norvegicus)


name: 3-hydroxy-3-methylglutarate + malonyl-CoA <=> (3S)-hydroxy-3-methylglutaryl-CoA + malonate


name: 2 H(+) + L-aspartate + 3 NADPH + 3 O2 => 2-nitrobutanedioate + 4 H2O + 3 NADP(+)


name: ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG (Bos taurus)


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Schizosaccharomyces pombe)


name: demethylphylloquinol + NADP(+) => demethylphylloquinone + H(+) + NADPH


name: Phosphorylated PER rebinds to phosphorylated TIM (Drosophila melanogaster)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Gallus gallus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O <=> a fatty acid + beta-D-glucosyl-(1<->1)-sphing-4-enine


name: GAB1 phosphorylation by EGFR kinase (Bos taurus)


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Sus scrofa)


name: (+)-artemisinic aldehyde + H2O + NADP(+) <=> (+)-artemisinate + 2 H(+) + NADPH


name: APP translocates from plasma membrane to endosome lumen (Homo sapiens)


name: TFAM binds to mitochondrial promoters (Saccharomyces cerevisiae)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Bos taurus)


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADA catalyzes the deamination of (deoxy)adenosine (Homo sapiens)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 6-deoxo-28-norcastasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 28-norcastasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: BDH2 dehydrogenates 3HBA (Rattus norvegicus)


name: Inhibition of integrin activation by sequestering PIP5KIgamma (Caenorhabditis elegans)


name: Dopa is oxidized to dopaquinone by TYR (Bos taurus)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Xenopus tropicalis)


name: acetyl-CoA + octan-1-ol = CoA + octyl acetate


name: a neolactoside nLc4Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + CMP + H(+)


name: (20S)-ginsenoside F2 + H(+) + UDP => (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Sus scrofa)


name: p-T,Y MAPK dimers translocate to nucleus (Gallus gallus)


name: GTSE1 promotes translocation of TP53 to the cytosol (Homo sapiens)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Xenopus tropicalis)


name: Full activation of MMP1 (Drosophila melanogaster)


name: DHFR2 reduces FOLA to DHF (Homo sapiens)


name: Digestion of linear starch (amylose) by extracellular amylase (Mus musculus)


name: Interaction of DAP12 and KIR2DS1 (Homo sapiens)


name: Gbeta:gamma activation of PLC beta (Mus musculus)


name: HIPK2 phosphorylates RUNX1 and EP300 (Canis familiaris)


name: FRS2 is phosphorylated by active TrkA receptor (Mus musculus)


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine


name: a tertiary amine + S-adenosyl-L-methionine <=> a methylated tertiary amine + H(+) + S-adenosyl-L-homocysteine


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)


name: Follitropin is a heterodimer (Gallus gallus)


name: CDP-alpha-D-glucose + D-glucose 6-phosphate = alpha,alpha-trehalose 6-phosphate + CDP + H(+)


name: chloride(out) + formate(in) => chloride(in) + formate(out)


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Bos taurus)


name: a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA


name: a thiol + S-adenosyl-L-methionine => a methyl thioether + H(+) + S-adenosyl-L-homocysteine


name: ATP + L-valine + tRNA(Val) <=> AMP + diphosphate + L-valyl-tRNA(Val)


name: 1,2-di-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphoethanolamine