name: H(+) + N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Drosophila melanogaster)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Schizosaccharomyces pombe)


name: 5-hydroxymethyl-dUMP + H2O = 2-deoxy-D-ribose 5-phosphate + 5-hydroxymethyluracil


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Gallus gallus)


name: ABCAs mediate lipid influx (Plasmodium falciparum)


name: [phosphate](n) + GTP <=> [phosphate](n+1) + GDP


name: 9-cis-retinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 9-cis-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + D-lysine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate => ADP + H(+) + N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine + phosphate


name: OPTN recruits CYLD to the TNFR1 complex (Homo sapiens)


name: 3-oxopropanoate + H(+) + H2O2 + nitrite => H2O + O2 + propionate 3-nitronate


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 <=> N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-taurine


name: Na(+)(in) + propanoate(in) => Na(+)(out) + propanoate(out)


name: Cleavage of Intronless Pre-mRNA at 3'-end (Rattus norvegicus)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Danio rerio)


name: 16-methoxytabersonine + O2 + reduced [NADPH--hemoprotein reductase] => (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Danio rerio)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Rattus norvegicus)


name: (2E)-triacontenoyl-CoA + H2O => (3R)-hydroxytriacontanoyl-CoA


name: Binding of the influenza virion to the host cell (Homo sapiens)


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Bos taurus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Bos taurus)


name: Nephrin trans-homophilic interaction (Rattus norvegicus)


name: NH4(+) + tetradecanoate => H2O + tetradecamide


name: Activated FGFR1 binds FLRT1,2,3 (Drosophila melanogaster)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Mus musculus)


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Schizosaccharomyces pombe)


name: L-gulonate + NAD(+) => 3-dehydro-L-gulonate + H(+) + NADH


name: UROD decarboxylates URO1 to COPRO1 (Mus musculus)


name: GNLY is transferred to the phagosome (Gallus gallus)


name: dehydrogriseofulvin + H(+) + S-adenosyl-L-homocysteine => desmethyl-dehydrogriseofulvin + S-adenosyl-L-methionine


name: (2R)-3-phosphoglycerate + alpha-D-glucose 1,6-bisphosphate + H(+) => (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 6-phosphate


name: p-S363,S380,T573 RS6K translocates to the nucleus (Homo sapiens)


name: Dissociation of the TP:Gq complex (Gallus gallus)


name: K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Mus musculus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 => 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Mus musculus)


name: IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Sus scrofa)


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Sus scrofa)


name: Digestion of linear starch (amylose) by extracellular amylase (Danio rerio)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Xenopus tropicalis)


name: TFR2 dimer binds 2xholoTF (Xenopus tropicalis)


name: Formation of RAD50:MRE11 complex (Caenorhabditis elegans)


name: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) => 5beta-pregnan-3,20-dione + H(+) + NADPH


name: IL7R is phosphorylated on Y499 (Homo sapiens)


name: TXLNA (IL14) binds syntaxin3 (Homo sapiens)


name: Activated JAK1 binds RAF1 (Rattus norvegicus)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Gallus gallus)


name: 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-heptadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA2 (d18:1(4E)/18:0) = CMP + ganglioside GM2 (d18:1(4E)/18:0) + H(+)


name: EPH:EFN dimers tetramerise (Homo sapiens)


name: HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Bos taurus)


name: Release Of ADP From Myosin (Gallus gallus)


name: D-mannonate + NAD(+) = H(+) + keto-D-tagaturonate + NADH


name: USP13 deubiquitinates BECN1,USP10 (Sus scrofa)


name: NADP(+) + undecan-1-ol => H(+) + NADPH + undecanal


name: YKI binds to SD and activates transcription (Drosophila melanogaster)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Sus scrofa)


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Bos taurus)


name: O2 + putrescine => 1-pyrroline + H2O2 + NH4(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ATP + H2O => a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor


name: HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane (Drosophila melanogaster)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Bos taurus)


name: thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Bos taurus)


name: DCAKD phosphorylates DP-CoA (Bos taurus)


name: NFE2L2 dependent BCL2 expression (Homo sapiens)


name: AH2 + archaeol + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + macrocyclic archaeol


name: RNF152 polyubiquitinates RRAGA (Mus musculus)


name: ATP(in) + H2O(in) + Zn(2+)(out) <=> ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in)


name: (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + octanoyl-CoA = (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + CoA


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-(4R)-hydroxysphinganine = (4R)-hydroxysphinganine + (5Z,8Z,11Z,14Z)-eicosatetraenoate


name: phosphate + sphing-4-enine => H2O + sphing-4-enine 1-phosphate


name: Binding of CBL to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)


name: NADP(+) + prostaglandin E1 <=> 15-oxoprostaglandin E1 + H(+) + NADPH


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+) + N(7)-methyl-GMP => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O


name: Clusterin binds C5b-C7, C8, C9 (Mus musculus)


name: Hh-Np traffics to the plasma membrane (Drosophila melanogaster)


name: Spike protein gets palmitoylated (Homo sapiens)


name: miR-19b microRNA binds CNOT6L mRNA (Homo sapiens)


name: Defective ACTH does not bind MCR2 (Homo sapiens)


name: Extracellular BTD hydrolyses BCTN (Xenopus tropicalis)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 A => 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 AH2


name: glycerol + H(+) + octanoate => H2O + octanoylglycerol


name: DEK binds TFAP2A homodimers (Drosophila melanogaster)


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Bos taurus)


name: prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer (Xenopus tropicalis)


name: (2R,3R)-tartrate(out) + succinate(in) <=> (2R,3R)-tartrate(in) + succinate(out)


name: FNTB inhibitors bind FNTA:FNTB (Schizosaccharomyces pombe)


name: Iodide is taken up by thyroid epithelial cells (Mus musculus)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + H2O + 2 oxidized [adrenodoxin]


name: PSIP1 binds MEN1 associated with MLL2 complex (Mus musculus)


name: template for synthesis of G-rich strand of telomere DNA activity


name: HTRA1 hydrolyzes ACAN (Aggrecan) (Rattus norvegicus)


name: GSK3 phosphorylates Nucleoprotein (Homo sapiens)


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Bos taurus)


name: SUMOylation of UBE2I with SUMO1 (Gallus gallus)


name: a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Bos taurus)


name: 3-O-alpha-L-mycarosylerythronolide B + dTDP + H(+) => dTDP-beta-L-mycarose + erythronolide B


name: INPP5E translocates to the primary cilium (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate <=> (-)-beta-barbatene + diphosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphate + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Rattus norvegicus)


name: 24-methylenecycloartanol + H(+) + S-adenosyl-L-homocysteine => cycloartenol + S-adenosyl-L-methionine


name: Translocation of PMAIP1 (NOXA) to mitochondria (Sus scrofa)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Caenorhabditis elegans)


name: Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine => Mg-protoporphyrin IX + S-adenosyl-L-methionine


name: AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)


name: Translocation of PKC theta to plasma membrane (Homo sapiens)


name: cytochrome-b5 reductase activity, acting on NADH


name: 3-oxododecanoate + H(+) => 2-undecanone + CO2


name: a hydroxy-epoxy-eicosatetraenoate => a hydroperoxyeicosatetraenoate


name: 2 5-aminolevulinate <=> H(+) + 2 H2O + porphobilinogen


name: H2O + N-acyl-15-methylhexadecasphing-4-enine = 15-methylhexadecasphing-4-enine + a fatty acid


name: Indirect recruitment of GAB2 to p-KIT (Canis familiaris)


name: ADP + H(+) + xylitol 5-phosphate => ATP + xylitol


name: α1-antagonists bind ADRA1A,B,D (Danio rerio)


name: ATF2 acetylates histone H2B, H4 (Xenopus tropicalis)


name: PXLP-K259-GOT1 transaminates alpha-ketoglutarate and aspartate (Plasmodium falciparum)


name: PA is converted to CDP-DAG by CDS1 (Dictyostelium discoideum)


name: CYP7A1 7-hydroxylates CHOL (Homo sapiens)


name: 4-aminobenzoate + 6-hydroxymethyl-7,8-dihydropterin <=> 7,8-dihydropteroate + H2O


name: Addition of nucleotides between position +11 and +30 (Schizosaccharomyces pombe)


name: a ganglioside GP1c + H2O => a ganglioside GQ1c + N-acetylneuraminate


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Xenopus tropicalis)


name: 2,5-dioxopentanoate + NH4(+) => 4-hydroxy-1-pyrroline-2-carboxylate + H(+) + H2O


name: L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine


name: pS181-S-Farn-Me KRAS4B binds BCL2L1 (Caenorhabditis elegans)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Dictyostelium discoideum)


name: 2 AMP + didemethylasterriquinone D + 2 diphosphate + H(+) => 2 ATP + 2 indole-3-pyruvate


name: (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH => (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+)


name: CYP3A4 oxidizes PREDN,PREDL (Xenopus tropicalis)


name: Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa (Homo sapiens)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 1-O-alkyl-sn-glycero-3-phosphocholine


name: 7,8-dihydroxy-4'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => 4',7,8-trihydroxyflavone + S-adenosyl-L-methionine


name: Surface deployment of platelet alpha granule membrane components (Gallus gallus)


name: IL6ST is tyrosine phosphorylated (Homo sapiens)


name: allocholate + deoxycholoyl-CoA => allocholoyl-CoA + deoxycholate


name: 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) => 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH


name: nicotinate beta-D-ribonucleotide + phenol => H(+) + nicotinate + phenyl 5-phospho-alpha-D-ribofuranoside


name: SUPV3L1 unwinds double-stranded mitochondiral RNA (Homo sapiens)


name: calcium-dependent protein serine/threonine phosphatase regulator activity


name: Activation of BAD by calcineurin (Homo sapiens)


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Mus musculus)


name: 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Caenorhabditis elegans)


name: Tropoelastin forms aggregate globules (Bos taurus)


name: L-methionyl-[protein] + S-adenosyl-L-methionine => S-adenosyl-L-homocysteine + S-methyl-L-methionyl-[protein]


name: SYS1 binds AcM-ARFRP1 (Dictyostelium discoideum)


name: UCKL1 phosphorylates urindine, cytidine (Drosophila melanogaster)


name: a phosphate monoester + H2O = an alcohol + phosphate


name: cholesterol + H(+) + NADH + O2 = 7-dehydrocholesterol + 2 H2O + NAD(+)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Saccharomyces cerevisiae)


name: CD320 binds extracellular TCN2:RCbl (Bos taurus)


name: UBA1 adenylates ubiquitin in the cytosol (Dictyostelium discoideum)


name: TXLNA (IL14) binds syntaxin3 (Mus musculus)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Mus musculus)


name: an alpha-Kdo-(2->6)-lipid IVA + ATP => a 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA + ADP + H(+)


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Sus scrofa)


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Bos taurus)


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Drosophila melanogaster)


name: Factor D cleaves C3b-bound Factor B (Sus scrofa)


name: 1D-myo-inositol 2,5-bisphosphate + H2O => 1D-myo-inositol 2-phosphate + phosphate


name: G alpha (q) binds to Trio family RhoGEFs (Mus musculus)


name: ATP + L-amino acyl-L-cysteinyl-[protein] <=> (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + ADP + H(+) + phosphate


name: 3-oxocholestane + A + H2O => 25-hydroxy 3-oxocholestane + AH2


name: PTK6 phosphorylates DOK1 (Caenorhabditis elegans)


name: Fusion of ERC and phagosome (Gallus gallus)


name: p-Y348-SYK dissociates (Canis familiaris)


name: (S,S)-butane-2,3-diol + NAD(+) = (S)-acetoin + H(+) + NADH


name: (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA + H2O => (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA


name: dodecanoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-dodecanoyl-4'-phosphopantetheine


name: Formation of RTC (Reverse Transcription Complex) (Homo sapiens)


name: 3-hydroxybenzoyl-CoA + H2O + NADP(+) => benzoyl-CoA + H(+) + NADPH + O2


name: an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+) => an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose


name: Addition of GlcNAc to position 5 by MGAT5 (Danio rerio)


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Mus musculus)


name: SLC26A3,6 exchange Cl- for HCO3- (Gallus gallus)


name: (R)-lactaldehyde + NAD(+) => H(+) + methylglyoxal + NADH


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Mus musculus)


name: Active MTORC1 phosphorylates ULK1 (Xenopus tropicalis)


name: (2S)-2-hydroxy-2-methyl-3,3-dimethylbutanenitrile => 3,3-dimethylbutan-2-one + hydrogen cyanide


name: ATP(in) + CoA(in) + decanoate(out) + H(+)(out) => AMP(in) + decanoyl-CoA(in) + diphosphate(in) + H(+)(in)


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Canis familiaris)


name: TBC1D17 binds OPTN:RAB8A (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: betaenone C + 3 H2O + 3 NADP(+) => dehydroprobetaenone I + 3 H(+) + 3 NADPH + 3 O2


name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Gallus gallus)


name: ADP(out) + dAMP(in) + H(+)(out) => ADP(in) + dAMP(out) + H(+)(in)


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O = 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + H(+) + phosphate


name: uridine(38/39) in tRNA => pseudouridine(38/39) in tRNA


name: glycine(out) + L-alanine(in) => glycine(in) + L-alanine(out)


name: STON2 binds SYT proteins (Gallus gallus)


name: 4-methylamino-4-dedimethylamino-anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine => 4-amino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine


name: 9beta-pimara-7,15-diene-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase]


name: CoA + H(+) + taurochenodeoxycholate => chenodeoxycholoyl-CoA + taurine


name: 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine = 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: phosphate + ribostamycin => 5''-phosphoribostamycin + H2O


name: 3beta,7beta-dihydroxyandrost-5-en-17-one + NADP(+) => 3beta-hydroxy-5-androstene-7,17-dione + H(+) + NADPH


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O <=> [(1->4)-alpha-D-galacturonosyl](n) + n H(+) + n methanol


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Bos taurus)


name: Dissociation of IRS-P from insulin receptor (Bos taurus)


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Xenopus tropicalis)


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Schizosaccharomyces pombe)


name: a fatty acyl-CoA + sphing-4-enine = an N-acylsphing-4-enine + CoA + H(+)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Sus scrofa)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3  phosphorylates STAT1,STAT3 (Rattus norvegicus)


name: a (N(7)-methyl 5'-triphospho-guanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+) => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: (2E,6E)-farnesyl diphosphate + H2O <=> 4-epi-cubebol + diphosphate


name: FPRL2 receptor binds a wide range of ligands (Xenopus tropicalis)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Rattus norvegicus)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Gallus gallus)


name: DHCR24 reduces ZYMOL to ZYMSTNL (Mus musculus)


name: ADP + CTP + 2 H(+) + phosphate => ATP + NH4(+) + UTP


name: NAT1,2 acetylate APAP-Cys to APAP-Mer (Sus scrofa)


name: Aquaporins passively transport water out of cells (Bos taurus)


name: Exocytosis of ficolin-rich granule membrane proteins (Plasmodium falciparum)


name: a sterol ester + H2O = a fatty acid + a sterol + H(+)


name: Activated NTRK2 binds FRS2 (Canis familiaris)


name: putrescine + spermidine = propane-1,3-diamine + sym-homospermidine


name: deamido-NAD(+)(in) + NAD(+)(out) = deamido-NAD(+)(out) + NAD(+)(in)


name: a carboxylate + acetyl-CoA => acetate + an acyl-CoA


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Sus scrofa)


name: ATP + H2O + selenate(out) = ADP + H(+) + phosphate + selenate(in)


name: 3 AH2 + 2 H(+) + heme b + 3 O2 => 3 A + Fe(2+) + 3 H2O + mycobilin a


name: p-4Y-PLCG1 dissociates from activated FGFR2 mutants (Homo sapiens)


name: adenosine(37) in tRNA + L-threonylcarbamoyladenylate => AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA


name: Cleavage of thymine by TDG glycosylase (Gallus gallus)


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Rattus norvegicus)


name: CHEK2 is recruited to DNA DSBs (Homo sapiens)


name: ARFGAPs stimulate ARF GTPase activity (Rattus norvegicus)


name: SMURF1 gene expression is stimulated by RUNX2 (Homo sapiens)


name: H(+) + NADPH + O2 + theobromine <=> 7-methylxanthine + formaldehyde + H2O + NADP(+)


name: 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + NADP(+)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Xenopus tropicalis)


name: D-maltose + phosphate <=> beta-D-glucose 1-phosphate + D-glucose


name: RAB31 GEFs exchange GTP for GDP on RAB31 (Rattus norvegicus)


name: (2S)-naringenin + dimethylallyl diphosphate = diphosphate + sophoraflavanone B


name: WDR5 binds Me2sR3-replicative histone H3 (Rattus norvegicus)


name: ASICs bind STOML3, (STOM) (Drosophila melanogaster)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Gallus gallus)


name: FAD + H(+) + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + FADH2


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Drosophila melanogaster)


name: L-glutamine(in) + L-phenylalanine(out) => L-glutamine(out) + L-phenylalanine(in)


name: alpha-D-Man-(1->3)-[alpha-D-GlcNAc-(1->2)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + H(+) + UDP => alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + UDP-N-acetyl-alpha-D-glucosamine


name: (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O2 => (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H(+)


name: CMP-N-acetyl-beta-neuraminate + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine <=> CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-galactosamine


name: [(1->2)-beta-D-glucosyl](n-2) + sophorose => [(1->2)-beta-D-glucosyl](n) + H2O


name: fumonisin B1 + 2 H2O = (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + 2 H(+) + 2 tricarballylate


name: N(6),N(6)-dimethyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: alcohol-forming very long-chain fatty acyl-CoA reductase activity


name: T1R2/T1R3 dimer is a sweet taste receptor (Homo sapiens)


name: 4'-hydroxyechinenone + A + H2O => AH2 + echinenone + O2


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 => (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 5-hydroxy-L-tryptophan


name: 3'-phosphoadenylyl sulfate + taurocholate <=> adenosine 3',5'-bisphosphate + H(+) + taurocholate 7-sulfate


name: H2O + substance P = L-Leu-L-Met-NH2 + substance P(1-9)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Mus musculus)


name: IGFBP1 binds IGF forming IGF:IGFBP1 (Mus musculus)


name: Activation of RAC1 by VAV (Canis familiaris)


name: L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)


name: MAT1A multimers transfer Ado from ATP to L-Met (Danio rerio)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-4-phosphate) + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Rattus norvegicus)


name: a 1-O-alkyl-2-acetyl-sn-glycerol + H2O => 1-O-alkyl-sn-glycerol + acetate + H(+)


name: Inactivation of APC/C via CDC20 sequestration (Saccharomyces cerevisiae)


name: an aromatic L-alpha-amino acid(out) + L-thyroxine(in) => an aromatic L-alpha-amino acid(in) + L-thyroxine(out)


name: PGG2 is reduced to PGH2 by PTGS2 (Rattus norvegicus)


name: (S)-2,3-diaminopropanoate + H(+) + H2O = 2 NH4(+) + pyruvate


name: TUT4,TUT7 oligouridylate mRNA (Homo sapiens)


name: H2O + raucaffricine = D-glucose + vomilenine


name: TP53 binds the TIGAR gene (Homo sapiens)


name: D-fructose + D-glucose <=> D-glucono-1,5-lactone + D-sorbitol


name: Phosphorylation of Cyclin A:Cdk2 at Tyr 15 (Homo sapiens)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Dictyostelium discoideum)


name: benzoate + 2 H(+) + NADPH => benzaldehyde + H2O + NADP(+)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Sus scrofa)


name: p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4) (Homo sapiens)


name: N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate (Xenopus tropicalis)


name: CYP8B1 12-hydroxylates 4CHOL7a,27DONE (Danio rerio)


name: (9Z,12Z)-octadecadienoate + O2 <=> (9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: [mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + AH2 + S-adenosyl-L-methionine = 5'-deoxyadenosine + [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + A + H(+) + L-methionine


name: 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA


name: D-fructopyranose(out) + Na(+)(out) => D-fructopyranose(in) + Na(+)(in)


name: PTGS1 dimer binds PTGS1 Inhibitors (Homo sapiens)


name: p-S400-Cot phosphorylates NIK (Bos taurus)


name: TRAIL binds TRAIL receptors (Gallus gallus)


name: 2-hydroxyhexanoate + O2 <=> 2-oxohexanoate + H2O2


name: oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor


name: "With a quinone or similar compound as acceptor"


name: TRAF6 is K63 poly-ubiquitinated (Dictyostelium discoideum)


name: TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphate => 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (Rattus norvegicus)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Danio rerio)


name: CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Mus musculus)


name: SERPINA6 binds PREDN (Caenorhabditis elegans)


name: 14-3-3-zeta binds Raf1 (Canis familiaris)


name: KCNJs transport K+ from the extracellular region to cytosol (Sus scrofa)


name: 3'-phosphoadenylyl sulfate + beta-D-Gal-(1<->1')-Cer => 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+)


name: [(1->4)-beta-D-mannuronosyl](n) + GDP-alpha-D-mannuronate = [(1->4)-beta-D-mannuronosyl](n+1) + GDP + H(+)


name: ATP + beta-alanine + tryptamine = AMP + beta-alanyl-tryptamine + diphosphate + H(+)


name: BESTs transport cytosolic Cl- to extracellular region (Sus scrofa)


name: (E)-(indol-3-yl)acetaldehyde oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-tryptophan


name: Secretion of collagens (Canis familiaris)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol = (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Drosophila melanogaster)


name: ATP + N(2)-(2-carboxyethyl)-L-arginine => AMP + deoxyamidinoproclavaminate + diphosphate + H(+)


name: (3S)-3-hydroxy-L-ornithine + CO2 + succinate => 2-oxoglutarate + L-ornithine + O2


name: MAP3K5 phosphorylates MKK3 and MKK6 (Homo sapiens)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Drosophila melanogaster)


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Drosophila melanogaster)


name: Opsins binds G alpha-t (Canis familiaris)


name: alpha,alpha-trehalose(out) + N(pros)-phospho-L-histidyl-[protein] <=> alpha,alpha-trehalose 6-phosphate(in) + L-histidyl-[protein]


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Bos taurus)


name: 3-dehydro-L-erythronate + ATP = 3-dehydro-4-O-phospho-L-erythronate + ADP + H(+)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (15S)-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Xenopus tropicalis)


name: all-trans-4-hydroxy-13,14-dihydroretinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> all-trans-4-oxo-13,14-dihydroretinoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: CES1,CES2 hydrolyze ASA- to ST (Gallus gallus)


name: a monoacylglycerol + H2O <=> a fatty acid + glycerol + H(+)


name: "sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)"


name: chloride(in) + glycine betaine(in) + 2 Na(+)(in) => chloride(out) + glycine betaine(out) + 2 Na(+)(out)


name: cysteamine + phosphate => cysteamine S-phosphate + H2O


name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Xenopus tropicalis)


name: Activation of PAKs by RAC1 and CDC42 (Danio rerio)


name: Dissociation of CANX from nonameric complex (Mus musculus)


name: Na(+)(in) + nicotinate(in) => Na(+)(out) + nicotinate(out)


name: chlorophyllide a + H2O => 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Schizosaccharomyces pombe)


name: dihydropyrimidine dehydrogenase (NADP+) activity


name: PRC1 SUMOylates CASP8AP2 with SUMO1 (Bos taurus)


name: AR binds AR agonists (Drosophila melanogaster)


name: kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin (Homo sapiens)


name: 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP(+) = (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one + H(+) + NADPH


name: S-methyl-5-thio-D-ribulose 1-phosphate <=> 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate


name: 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+) => 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + CO2


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Mus musculus)


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)


name: (2E)-geranyl diphosphate => alpha-pinene + diphosphate


name: NRF1:p-PPARGC1A, NRF2 bind the TFB2M promoter (Homo sapiens)


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Canis familiaris)


name: NPM1-ALK-dependent BCL2A1 gene expression (Homo sapiens)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Xenopus tropicalis)


name: FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer (Saccharomyces cerevisiae)


name: AH2 + ecdysone + O2 = 20-hydroxyecdysone + A + H2O


name: Haptoglobin-related Protein binds Hemoglobin (Rattus norvegicus)


name: ATP + H2O + taurocholate(out) = ADP + H(+) + phosphate + taurocholate(in)


name: O2 + reduced [NADPH--hemoprotein reductase] + ursodeoxycholate = beta-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2'-hydroxybiphenyl-2-sulfinate + FMN + H(+) + H2O + NAD(+) => dibenzothiophene 5,5-dioxide + FMNH2 + NADH + O2


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)


name: Formation of DSIF:NELF:early elongation complex (Gallus gallus)


name: a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SFTPB dimer,C translocate from multivesicle body to lamellar body (Sus scrofa)


name: 4-hydroxyphenylacetyl-CoA + H2O = 4-hydroxyphenylacetate + CoA + H(+)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Drosophila melanogaster)


name: L-arginine(in) + L-leucine(out) => L-arginine(out) + L-leucine(in)


name: USP44 deubiquitinates CDC20 (Canis familiaris)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b (Drosophila melanogaster)


name: RAB1:GTP recruits GBF1 to the ERGIC (Bos taurus)


name: acetoacetyl-CoA + H(+) + NADH => 3-hydroxybutanoyl-CoA + NAD(+)


name: glucosylglycerol transmembrane transporter activity


name: ATP + H2O + L-phenylalanine = AMP + D-phenylalanine + diphosphate + H(+)


name: ATP + H2O + L-alanyl-L-glutamate(out) <=> ADP + H(+) + L-alanyl-L-glutamate(in) + phosphate


name: an N-(fatty acyl)-L-leucine + H2O <=> a fatty acid + L-leucine


name: (S)-cis-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-1-hydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SDK1 homophillic interaction (Homo sapiens)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Caenorhabditis elegans)


name: Spermidine  => N-acetylated spermidine (Bos taurus)


name: GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC (Canis familiaris)


name: 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O => 2-glutaroyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phospholipid + a triacylglycerol => a 1,2-diacylglycerol + a glycerophospholipid


name: Caspase-mediated cleavage of occludin (Canis familiaris)


name: 10-formyldihydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide <=> 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 7,8-dihydrofolate


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Gallus gallus)


name: TASP1 cleaves KMT2A (Xenopus tropicalis)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Mus musculus)


name: RHOQ translocates to the Golgi-associated vesicle membranes (Drosophila melanogaster)


name: dodecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(2-oxotridecyl)pyran-2-one + 3 CO2 + 4 CoA


name: 1-acyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 2-furoyl-CoA + A + H2O => 5-hydroxy-2-furoyl-CoA + AH2 + H(+)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Homo sapiens)


name: 3-hydroxyglutarate(out) + 3 Na(+)(out) = 3-hydroxyglutarate(in) + 3 Na(+)(in)


name: (S)-malyl-CoA + succinate => (S)-malate + succinyl-CoA


name: Phosphorylation of COP1 at Ser-387  by ATM (Sus scrofa)


name: Persulfide sulfur is dioxygenated (Bos taurus)


name: 12 ATP + L-asparagine + L-aspartate + L-cysteine + L-glutamate + L-histidine + 3 L-isoleucine + L-leucine + L-lysine + L-ornithine + L-phenylalanine <=> 12 AMP + bacitracin A + 12 diphosphate + 12 H(+) + H2O


name: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine => L-methionine + tetrahydropteroyltri-L-glutamate


name: D-sedoheptulose 7-phosphate isomerase activity


name: Liganded Gz-activating GPCR acts as a GEF for Gz (Caenorhabditis elegans)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Sus scrofa)


name: TBC1D20 binds RAB1:GTP (Schizosaccharomyces pombe)


name: AMP + diphosphate + NADP(+) + nonanal => ATP + H(+) + NADPH + nonanoate


name: ALDH3B1 oxidises HXAL to PALM (Mus musculus)


name: NAD(+) + prostaglandin A1 = 15-oxo-prostaglandin A1 + H(+) + NADH


name: (2Z,4Z)-2-hydroxyhepta-2,4-diene-1,7-dioate + CO2 => (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+)


name: holo-[citrate lyase ACP] + S-acetylphosphopantotheine = (R)-4'-phosphopantetheine + acetyl-[citrate lyase ACP]


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Sus scrofa)


name: 5alpha-cholest-8,14-dien-3beta-ol + H(+) + NADPH = 5alpha-cholest-8-en-3beta-ol + NADP(+)


name: acetyl-CoA + L-lysine = CoA + H(+) + N(6)-acetyl-L-lysine


name: diphosphate + RNA(n)-3'-uridine ribonucleotide => RNA(n) + UTP


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine = 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA


name: precorrin-6B + 2 S-adenosyl-L-methionine = CO2 + 3 H(+) + precorrin-8X + 2 S-adenosyl-L-homocysteine


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Bos taurus)


name: 1,2-dihydro-alpha-santonin + NAD(+) <=> alpha-santonin + H(+) + NADH


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Rattus norvegicus)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Canis familiaris)


name: Collagen type V degradation by MMP2,9,10 (Sus scrofa)


name: p-PKR dimer phosphorylates PPP2R5A (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MIB2 ubiquitinates CYLD at K338, K530 (Danio rerio)


name: TLE tetramers bind TCF/LEF at WNT promoters (Rattus norvegicus)


name: RCHY1 binds POLH (Drosophila melanogaster)


name: ATP + L-threonyl-[myosin light chain] => ADP + H(+) + O-phospho-L-threonyl-[myosin light chain]


name: L-lysyl-[glycine-cleavage complex H protein] + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => L-lysyl-[lipoyl-carrier protein] + N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein]


name: acetyl-CoA + dodecanedioyl-CoA => 3-oxotetradecanedioyl-CoA + CoA


name: (6S)-5,6,7,8-tetrahydrofolate + N-formimidoyl-L-glutamate => 5-formimidoyltetrahydrofolate + L-glutamate


name: (2E)-octadecenoyl-[ACP] + H2O => (3R)-hydroxyoctadecanoyl-[ACP]


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ATP + H2O <=> a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ADP + H(+) + phosphate


name: 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + CTP = CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonate + diphosphate


name: hexanoyl-CoA + NAD(+) = (2E)-hexenoyl-CoA + H(+) + NADH


name: Fibronectin degradation by ADAM8 (Sus scrofa)


name: ABHD4 hydrolyses NAPE (Canis familiaris)


name: Cleavage of DFF45 (224) by caspase-3 (Sus scrofa)


name: a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Homo sapiens)


name: RHOF GAPs stimulate RHOF GTPase activity (Gallus gallus)


name: Activated FGFR1 phosphorylates FRS2 (Caenorhabditis elegans)


name: adenosylcobyric acid synthase (glutamine-hydrolyzing) activity


name: Association of ADAM and B4GALT1 With ZP3 (Mus musculus)


name: IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Mus musculus)


name: GDP + H(+) + mannosylinositol phosphorylphytoceramide => an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + GDP-alpha-D-mannose


name: KIAA0101 double monoubiquitination (Xenopus tropicalis)


name: (25R)-3beta-hydroxy-5-cholestenoate + H2O + 2 oxidized [adrenodoxin] => (25R)-3beta-hydroxy-5-cholesten-26-al + H(+) + O2 + 2 reduced [adrenodoxin]


name: H2O + N-(9Z-octadecenoyl)-sphing-4-enine <=> (9Z)-octadecenoate + sphing-4-enine


name: N-acetyl-D-glucosamine + UDP-alpha-D-galactose => beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + H(+) + UDP


name: a fatty acyl-CoA + a sphingoid base = an N-acyl-sphingoid base + CoA + H(+)


name: Aquaporins passively transport glycerol out of cells (Gallus gallus)


name: MAD2 associates with the Mad1 kinetochore complex (Canis familiaris)


name: TRIM21 ubiquitinates SQSTM1 (Sus scrofa)


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Homo sapiens)


name: voltage-gated monoatomic anion channel activity


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Homo sapiens)


name: GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol (Dictyostelium discoideum)


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Xenopus tropicalis)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(13Z,16Z,19Z)-docosatrienoyl-CoA + CO2 + CoA


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Homo sapiens)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Bos taurus)


name: Phosphorylation of UBF-1:rDNA Promoter (Rattus norvegicus)


name: sucrose + UDP-alpha-D-galactose => 6(F)-alpha-D-galactosylsucrose + H(+) + UDP


name: NEIL1 translocates to the nucleus (Gallus gallus)


name: (+)-abscisic acid D-glucopyranosyl ester + H2O = 2-cis-(+)-abscisate + beta-D-glucose + H(+)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Rattus norvegicus)


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Homo sapiens)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Gallus gallus)


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeraniol + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + plaunotol


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Homo sapiens)


name: all-trans retinoic acid 3,4-desaturase activity


name: MAOA:FAD deaminates DA to DOPAC (Mus musculus)


name: guanosine(37) in tRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Homo sapiens)


name: Excess homocysteine yields homolanthionine and H2S (Dictyostelium discoideum)


name: transcription factor TFIIH holo complex binding


name: 2 gamma-L-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH


name: NEU4 hydrolyses Neu5Ac from glycoconjugates (Homo sapiens)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Canis familiaris)


name: PI3K produces PIP3 and other phosphatidyl inositides (Sus scrofa)


name: glycocholate + NAD(+) <=> 7-oxo-glycodeoxycholate + H(+) + NADH


name: nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement (Homo sapiens)


name: formononetin + O2 + reduced [NADPH--hemoprotein reductase] <=> 2'-hydroxyformononetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 11-cis-retinyl tetradecanoate + CoA => 11-cis-retinol + tetradecanoyl-CoA


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Mus musculus)


name: CYCS:APAF1 binds procaspase-9 (Xenopus tropicalis)


name: but-3-en-2-one + H(+) + NADPH => butan-2-one + NADP(+)


name: p-ULK1 phosphorylates DENND3 (Homo sapiens)


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-galctosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: Interaction of KIT and sSCF (Mus musculus)


name: GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC (Rattus norvegicus)


name: (3S)-hydroxyoctanoyl-CoA => (2E)-octenoyl-CoA + H2O


name: intramolecular oxidoreductase activity, interconverting keto- and enol-groups


name: ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate


name: SUMOylation of HDAC1 with SUMO1 (Sus scrofa)


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Bos taurus)


name: H2O + N-hexacosanoylglycine => glycine + hexacosanoate


name: NMRK2 phosphorylates NR to yield NMN (Bos taurus)


name: FUT3 transfers L-fucose to Gal1,3GlcNAc (Bos taurus)


name: Autophosphorylation of PAK (Homo sapiens)


name: Autophosphorylation of BTK/ITK (Drosophila melanogaster)


name: 2-deoxy-D-glucose 6-phosphate + H2O <=> 2-deoxy-D-glucose + phosphate


name: a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein] => a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: inositol monophosphate 1-phosphatase activity


name: Phosphorylation of YAP by LATS2 (Mus musculus)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Gallus gallus)


name: N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine


name: CHL1 interacts with Ankyrin-G (Homo sapiens)


name: glutathione disulfide oxidoreductase activity


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Homo sapiens)


name: 2-oxoglutarate + L-kynurenine = H2O + kynurenate + L-glutamate


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Danio rerio)


name: beta-cryptoxanthin + O2 <=> (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) => a 1-acyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: 12alpha,13alpha-dihydroxyfumitremorgin C + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => fumitremorgin C + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine => 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: (Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 <=> (-)-4'-methoxycyclopenine + CO2 + succinate


name: Formation of ORC(2-5) complex (Saccharomyces cerevisiae)


name: SLC36A1-mediated uptake of glycine, proline, and alanine (Gallus gallus)


name: (S)-4-aminopentanoate + H2O + NAD(+) => 4-oxopentanoate + H(+) + NADH + NH4(+)


name: PAK1-3 phosphorylates VE-cadherin (Danio rerio)


name: ATP + ergothioneine(out) + H2O <=> ADP + ergothioneine(in) + H(+) + phosphate


name: phosphate(in) + succinate(out) => phosphate(out) + succinate(in)


name: RHOF binds effectors at the plasma membrane (Xenopus tropicalis)


name: H2O + O2 + S-sulfanylglutathione => glutathione + 2 H(+) + sulfite


name: 7-oxo-taurodeoxycholate + H(+) + NADH => NAD(+) + taurocholate


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Caenorhabditis elegans)


name: MAPK6 is degraded by the 26S proteasome (Saccharomyces cerevisiae)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Drosophila melanogaster)


name: Digestion of linear starch (amylose) by extracellular amylase (Rattus norvegicus)


name: Disassociation of PLC-gamma1 from SLP-76 (Rattus norvegicus)


name: Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity


name: dGMP + NAD(+) <=> H(+) + N(2)-(ADP-D-ribosyl)-dGMP + nicotinamide


name: Disassembly of SR-BI-bound spherical HDL (Mus musculus)


name: CO2 + D-ribulose 5-phosphate + NADH => 6-phospho-D-gluconate + NAD(+)


name: Sulfate is exported to the cytosol in exchange for dicarboxylate (Drosophila melanogaster)


name: The COG complex binds RABs at the Golgi membrane (Xenopus tropicalis)


name: PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Rattus norvegicus)


name: chloride(out) + 2 Na(+)(out) + taurine(out) => chloride(in) + 2 Na(+)(in) + taurine(in)


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Saccharomyces cerevisiae)


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Mus musculus)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Mus musculus)


name: Rap1 signal termination by Rap1GAPs (Caenorhabditis elegans)


name: DHODH:FMN binds DHODH inhibitors (Caenorhabditis elegans)


name: Translocation of TGN-lysosome vesicle to lysosome (Rattus norvegicus)


name: cholesterol + NAD(+) = cholest-5-en-3-one + H(+) + NADH


name: 9-cis-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9-cis-retinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = 1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA (Dictyostelium discoideum)


name: A + D-alanine + H2O = AH2 + NH4(+) + pyruvate


name: 25(R) THCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)


name: (2E)-butenoyl-CoA + FADH2 => butanoyl-CoA + FAD + H(+)


name: AKT phosphorylates IKKalpha (Drosophila melanogaster)


name: CO2 + hydroquinone => 2,5-dihydroxybenzoate + H(+)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Homo sapiens)


name: 4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = alpha-D-glucose 1-phosphate + D-gluconate


name: 2 H(+) + 2 H2O + 2 tellimagrandin II => 2 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + O2


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Homo sapiens)


name: 1-tetradecanoyl-sn-glycerol 3-phosphate + H2O => 1-tetradecanoyl-sn-glycerol + phosphate


name: 4-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase]


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Drosophila melanogaster)


name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + A + 2 H2O => (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + AH2 + O2


name: H2O + hypochlorous acid => chloride + H(+) + H2O2


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Xenopus tropicalis)


name: dimethylallyl diphosphate + H2O + yaequinolone E <=> [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate


name: acetyl-CoA + L-threonyl-[protein] => CoA + O-acetyl-L-threonyl-[protein]


name: Defective MTR does not transfer CH3 group from MTHF to cob(I)alamin (Homo sapiens)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-hexacosanoylsphinganine + O2 = 2 Fe(III)-[cytochrome b5] + H2O + N-hexacosanoyl-(4R)-hydroxysphinganine


name: (4R)-ipsdienol + NAD(+) = H(+) + ipsdienone + NADH


name: TFAM binds to mitochondrial promoters (Xenopus tropicalis)


name: 3-bromo-L-tyrosyl-[protein] + 2 H2O => bromide + H(+) + H2O2 + L-tyrosyl-[protein]


name: dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + reduced [flavodoxin] => dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + H(+) + H2O + oxidized [flavodoxin]


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Caenorhabditis elegans)


name: CO2 + GDP + phosphoenolpyruvate => GTP + oxaloacetate


name: 3-hydroxybenzyl alcohol + acetyl-CoA <=> 3-hydroxy-benzyl acetate + CoA


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Homo sapiens)


name: 4-pyridoxolactone + H2O = 4-pyridoxate + H(+)


name: RNF41 binds neuregulin-activated ERBB3 (Drosophila melanogaster)


name: chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] => 3,8-divinyl chlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Dictyostelium discoideum)


name: hexadecane-1,2-diol + 2 hexadecanoyl-CoA <=> 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA


name: HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex (Drosophila melanogaster)


name: Translocation of active Cdc25C to the nucleus (Drosophila melanogaster)


name: a 2'-deoxyribonucleoside + a ribonucleoside 5'-phosphate = a 2'-deoxyribonucleoside 5'-phosphate + a ribonucleoside


name: 15-hydroxyhexadecanoate + H2O + NADP(+) => H(+) + hexadecanoate + NADPH + O2


name: H2O + N-(9Z-octadecenoyl)-L-leucine = (9Z)-octadecenoate + L-leucine


name: CoA + nonanoyl-AMP <=> AMP + H(+) + nonanoyl-CoA


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 => CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate


name: 3 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) = 3 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Rattus norvegicus)


name: [Pyr1]apelin-13 + H2O = [Pyr1]apelin-12 + L-phenylalanine


name: ECE2 cleaves EDN1(53-90) (Canis familiaris)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Sus scrofa)


name: 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: butanoate(out) + dehydroepiandrosterone 3-sulfate(in) => butanoate(in) + dehydroepiandrosterone 3-sulfate(out)


name: Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Drosophila melanogaster)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Xenopus tropicalis)


name: HS-GAGs translocate to the lysosome for degradation (Drosophila melanogaster)


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Mus musculus)


name: Co(2+)(in) + 2 hydrogencarbonate(in) => Co(2+)(out) + 2 hydrogencarbonate(out)


name: Recruitment of POLB to the AP site (Canis familiaris)


name: Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B (Homo sapiens)


name: PNPLA5 hydrolyzes TAG (Xenopus tropicalis)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Canis familiaris)


name: RASA1 stimulates RAS GTPase activity (Gallus gallus)


name: Collagen type III degradation by MMP14 (Gallus gallus)


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Bos taurus)


name: 3-hydroxy-2-methylpyridine-5-carboxylate + NADPH + O2 <=> 2-(acetamidomethylene)succinate + NADP(+)


name: Prokineticin receptors bind prokineticin (Rattus norvegicus)


name: adenosine(4) in tRNA(His) + S-adenosyl-L-methionine <=> 2'-O-methyladenosine(4) in tRNA(His) + H(+) + S-adenosyl-L-homocysteine


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Mus musculus)


name: AMP + diphosphate + sulfoacetyl-CoA => ATP + CoA + sulfoacetate


name: dioctanoylglycerol + H2O <=> H(+) + octanoate + octanoylglycerol


name: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] => all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: all-trans-beta-carotene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + O2 + reduced [NADPH--hemoprotein reductase] => (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Bos taurus)


name: Digestion of linear starch (amylose) by extracellular amylase (Xenopus tropicalis)


name: PTK2 binds activated EGFR (Caenorhabditis elegans)


name: emodin anthrone + O2 => emodin + H(+) + H2O


name: Insulin receptor de-phosphorylation (Canis familiaris)


name: a sphingoid 1-phosphate = a fatty aldehyde + phosphoethanolamine


name: 2 L-cysteine + NAD(+) <=> H(+) + L-cystine + NADH


name: Activated MAPKs phosphorylate BRAF (Drosophila melanogaster)


name: H2O + N(alpha)-acetyl-L-methionine => acetate + L-methionine


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Caenorhabditis elegans)


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Dictyostelium discoideum)


name: protein-glycine ligase activity, initiating


name: P4HB forms mixed disulphides with Hh precursors (Gallus gallus)


name: alpha-D-ribose 1,5-bisphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP


name: FOXM1 stimulates CDC25A transcription (Homo sapiens)


name: a carboxylate + H(+) + H2O2 => a percarboxylic acid + H2O


name: ATP binds G-protein beta associated TRiC/CCT (Homo sapiens)


name: ALDH8A1 oxidises 9cRAL to 9cRA (Canis familiaris)


name: (-)-dehydrodiconiferyl acid ketone + a quinol => (-)-dehydrodiconiferyl acid + a quinone


name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Canis familiaris)


name: AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Sus scrofa)


name: LPA-binding receptors bind LPA (Danio rerio)


name: Proteolytic PAK-2p34 fragment translocates to the nucleus (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate => 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA


name: GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP (Gallus gallus)


name: 2 fonsecin B + H(+) + NADPH + O2 <=> bifonsecin B + 2 H2O + NADP(+)


name: 1-O-hexadecyl-2-propanoyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: Crk binding to p130cas (Canis familiaris)


name: (8R)-8-hydroxynonanoyl-CoA + O2 <=> (2E,8R)-8-hydroxynonenoyl-CoA + H2O2


name: coenzyme F420-2 alpha-glutamyl ligase activity


name: PAK2 binds NCK (Drosophila melanogaster)


name: TP53BP1 recruits DCLRE1C to ATM (Sus scrofa)


name: Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Canis familiaris)


name: E-cadherin degradation by ADAM10, ADAM15 (Rattus norvegicus)


name: 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine => 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: NGF:p75NTR complex binds to NRAGE (Homo sapiens)


name: L-galactonate => 2-dehydro-3-deoxy-L-galactonate + H2O


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H(+) + ubiquinol-10 => trans-4-hydroxy-L-proline + ubiquinone-10


name: Translocation of active Cdc25C to the nucleus (Canis familiaris)


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + ATP + H2O => 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + ADP + H(+) + phosphate


name: MigFilin associates with Filamin and F-actin (Dictyostelium discoideum)


name: N(delta)-hydroxy-N(omega)-methyl-L-arginine + NADH + O2 = H2O + N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + NAD(+)


name: Cleavage of DFF45 (224) by caspase-3 (Drosophila melanogaster)


name: Netrin-1 induced DCC clustering (Homo sapiens)


name: ALDH3A2-1 oxidises HD2NAL to PALM (Drosophila melanogaster)


name: 1-O-(alk-1-enyl)-sn-glycero-3-phosphate + H2O <=> 1-O-(alk-1-enyl)-sn-glycerol + phosphate


name: high-affinity phosphate transmembrane transporter activity


name: isocitrate <=> citrate (Dictyostelium discoideum)


name: Activated FGFR3:p-SHC1 binds GRB2:SOS1 (Mus musculus)


name: protoaphin aglucone <=> H2O + xanthoaphin


name: 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] <=> coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H(+)(out) + L-methionine(in) => H(+)(in) + L-methionine(out)


name: Fibronectin degradation by CTSG (Rattus norvegicus)


name: H(+) + 2 NADPH + O2 + octadecanal => formate + H2O + heptadecane + 2 NADP(+)


name: RFC dissociates after sliding clamp formation (Rattus norvegicus)


name: Liganded Gz-activating GPCR acts as a GEF for Gz (Canis familiaris)


name: RHOU auto-activates (Dictyostelium discoideum)


name: 3-dehydro-6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 3-dehydroteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase] <=> 8-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Dictyostelium discoideum)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Mus musculus)


name: Activation of RAC1 by the PXN:CRK complex (Caenorhabditis elegans)


name: SULT1A3,4 dimers sulfate DA to DAOS (Rattus norvegicus)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Plasmodium falciparum)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: Phosphorylation of ChREBP at Thr(653) by PKA (Homo sapiens)


name: GDIs block activation of RHOB (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + a 12-hydroxyjasmonate => a 12-sulfojasmonate + adenosine 3',5'-bisphosphate + H(+)


name: H(+) + NADH + O2 + phenol = H2O + hydroquinone + NAD(+)


name: L-threo-tetrahydrobiopterin + 2 NADP(+) => 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH


name: dTDP-6-deoxy-alpha-D-allose + NADP(+) <=> dTDP-4-dehydro-6-deoxy-alpha-D-allose + H(+) + NADPH


name: (3R)-hydroxy-5-methylhexanoyl-[ACP] => (2E)-5-methylhexenoyl-[ACP] + H2O


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Sus scrofa)


name: Defective HLCS does not biotinylate 6x(PCCA:PCCB) (Homo sapiens)


name: CDC6 association with ORC(1-6) at replication origins (Dictyostelium discoideum)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Bos taurus)


name: ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: (3S)-hydroxydecanoyl-CoA => (2E)-decenoyl-CoA + H2O


name: 9-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 9-hydroxy-octadecanoate + H(+)


name: 19-O-acetylhorhammericine + CoA => acetyl-CoA + horhammericine


name: 5-methylcytidine(2499) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(2499) in 23S rRNA + S-adenosyl-L-methionine


name: Activated FGFR4 phosphorylates FRS3 (Caenorhabditis elegans)


name: (2S)-flavan-4-ol + NADP(+) => (2S)-flavanone + H(+) + NADPH


name: S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] => glyoxal + L-cysteinyl-[protein]


name: 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA => (9Z)-octadecenoyl-CoA + 1-O-hexadecyl-sn-glycero-3-phosphocholine


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Gallus gallus)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Saccharomyces cerevisiae)


name: [(1S)-1-acetamidoethyl]phosphonate + CoA => (S)-1-aminoethylphosphonate + acetyl-CoA


name: Orc1 is phosphorylated by cyclin A/CDK2 (Schizosaccharomyces pombe)


name: 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphate + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + phosphate


name: ZnT5 transports zinc into the golgi apparatus (Sus scrofa)


name: OPN1MW binds 11cRAL (Xenopus tropicalis)


name: Secretion and activation of the latent large complex of TGF-beta-1 (Drosophila melanogaster)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Gallus gallus)


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Saccharomyces cerevisiae)


name: (R)-lipoate + L-lysyl-[lipoyl-carrier protein] => H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: 3-(pyrazol-1-yl)-L-alanine + acetate + H(+) => O-acetyl-L-serine + pyrazole


name: AXIN is ubiquitinated by SMURF2 (Mus musculus)


name: NTPDase3 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)


name: KIR2DS1 interacting with HLA-C group 2 (Cw4) (Rattus norvegicus)


name: GRIK3 homomer binds glutamate (Homo sapiens)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Mus musculus)


name: SUMOylation of NR1H4 with SUMO1 (Danio rerio)


name: dihydrocarvone + H(+) + NADPH + O2 => 6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: PHF8 demethylates MeK21-histone H4 (Canis familiaris)


name: SLC6A15-mediated amino acid uptake (Xenopus tropicalis)


name: p-S256-Aquaporin-2 passively transports water into cell (Sus scrofa)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O


name: L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: NEIL1 cleaves FapyG from damaged DNA (Rattus norvegicus)


name: bisphenol A + H(+) + NADH + O2 <=> 2,2-bis(4-hydroxyphenyl)-1-propanol + H2O + NAD(+)


name: 2-oxoglutarate + fumigatonoid C + O2 <=> CO2 + H2O + novofumigatonin + succinate


name: methylgalactoside transmembrane transporter activity


name: RAC2 binds effectors at the ER membrane (Bos taurus)


name: hexadecane-1,2-diol + 2 hexadecanoyl-CoA => 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA


name: AMP + ATP => adenosine 3'-diphosphate,5'-phosphate + AMP + H(+)


name: 13-cis-retinol + NAD(+) = 13-cis-retinal + H(+) + NADH


name: KLK5 cleaves and activates KLK8 (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate => casbene + diphosphate


name: PAPP-A2 proteolyzes IGF:IGFBP5:ALS (Homo sapiens)


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: Addition of nucleotides between position +11 and +30 (Mus musculus)


name: Caspase-mediated cleavage of alpha adducin (Sus scrofa)


name: (R)-4-phosphopantoate + ADP + H(+) => (R)-pantoate + ATP


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine


name: 3 H(+) + L-histidine + 2 NADH => H2O + L-histidinol + 2 NAD(+)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Sus scrofa)


name: SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Bos taurus)


name: 8-methylquinoline + A + H2O => 8-methylquinolin-2(1H)-one + AH2


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Mus musculus)


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Saccharomyces cerevisiae)


name: an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => an (E)-omega-(methylsulfanyl)-alkanal oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase]


name: H2O + S-formylglutathione <=> formate + glutathione + H(+)


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Sus scrofa)


name: 6-O-methylnorlaudanosoline + S-adenosyl-L-methionine = H(+) + nororientaline + S-adenosyl-L-homocysteine


name: [trehalose-6-phosphate synthase]-L-cysteine + S-adenosyl-L-methionine => [trehalose-6-phosphate synthase]-S-methyl-L-cysteine + H(+) + S-adenosyl-L-homocysteine


name: all-trans-zeaxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => all-trans-antheraxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Canis familiaris)


name: ornithine => putrescine + CO2 (Danio rerio)


name: CHST14 transfers SO4(2-) to GalNAc in dermatan or DS (Sus scrofa)


name: RCC1 stimulates GDP to GTP exchange on RAN (Gallus gallus)


name: Binding of IP3 to IP3 receptor (Bos taurus)


name: (2R)-2-(4-aminophenyl)-L-seryl-[peptidyl-carrier protein] + A + H2O => 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AH2 + O2


name: Removal of the third glucose by glucosidase II and release from the chaperone (Homo sapiens)


name: COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycerol + H(+) + phosphoethanolamine


name: TRiC/CCT binds unfolded G-protein beta subunit (Mus musculus)


name: L-alanine(in) + Na(+)(in) <=> L-alanine(out) + Na(+)(out)


name: H(+) + NADPH + O2 + tert-butanol <=> 2-methylpropane-1,2-diol + H2O + NADP(+)


name: Formation of collagen fibres (Canis familiaris)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Schizosaccharomyces pombe)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Saccharomyces cerevisiae)


name: CoA + H(+) + N-octadecanoylhexadecasphinganine => hexadecasphinganine + octadecanoyl-CoA


name: butanoyl-CoA + NADP(+) <=> (2E)-butenoyl-CoA + H(+) + NADPH


name: 3',3'-c-di-AMP + H2O => 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H(+)


name: The receptor:G-protein complex  binds GTP (Gallus gallus)


name: DOCK3 activates RAC1 (Xenopus tropicalis)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH => 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+)


name: O2 + quercetin <=> 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO


name: PTPN22 dissociates from CSK (Homo sapiens)


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Xenopus tropicalis)


name: Hyperactivation of factor X by FVIIIa:FIXa R384L (Homo sapiens)


name: TRiC/CCT binds unfolded G-protein beta subunit (Danio rerio)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Plasmodium falciparum)


name: (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate


name: Oligomerization of CARMA1 (Mus musculus)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Dictyostelium discoideum)


name: (S)-3-hydroxybutanoate(in) + H(+)(in) => (S)-3-hydroxybutanoate(out) + H(+)(out)


name: Filaggrin binds Keratin tonofilament:Desmosome (Canis familiaris)


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Gallus gallus)


name: SHC1 binds to the phosphorylated EGF receptor:ligand complex (Sus scrofa)


name: 3 2-oxoglutarate + gibberellin A53 + 3 O2 <=> 3 CO2 + gibberellin A17 + H(+) + H2O + 3 succinate


name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A => 4-amino-4-deoxy-beta-L-arabinopyranosyl-lipid A + di-trans,octa-cis-undecaprenyl phosphate


name: (R)-carnitine + propanoyl-CoA = CoA + O-propanoyl-(R)-carnitine


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Saccharomyces cerevisiae)


name: Co(I)-[dimethylamine-specific corrinoid protein] + dimethylamine + H(+) <=> methyl-Co(III)-[dimethylamine-specific corrinoid protein] + methylamine


name: (+-)-pavine + S-adenosyl-L-methionine <=> H(+) + N-methylpavine + S-adenosyl-L-homocysteine


name: a ganglioside GA1 + GDP-beta-L-fucose => a ganglioside Fuc-GA1 + GDP + H(+)


name: IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Gallus gallus)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Homo sapiens)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Gallus gallus)


name: H(+) + norspermidine + S-methyl-5'-thioadenosine => propane-1,3-diamine + S-adenosyl 3-(methylsulfanyl)propylamine


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Bos taurus)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Xenopus tropicalis)


name: a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] <=> an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: ADP + H(+) + O-phospho-L-threonyl-[receptor-protein] => ATP + L-threonyl-[receptor-protein]


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Rattus norvegicus)


name: H2O + peracetic acid = acetate + H(+) + H2O2


name: Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)


name: ERK5 translocates to the nucleus (Saccharomyces cerevisiae)


name: CoA + O-3-oxobutanoyl-(R)-carnitine => (R)-carnitine + acetoacetyl-CoA


name: deoxyspectinabilin + S-adenosyl-L-homocysteine => demethyldeoxyspectinabilin + S-adenosyl-L-methionine


name: ATP + H2O + pheophorbide a(in) = ADP + H(+) + pheophorbide a(out) + phosphate


name: (9Z,12Z)-octadecadienoyl-CoA + FAD + H(+) => (2E,9Z,12Z)-octadecatrienoyl-CoA + FADH2


name: 4'-apo-beta-carotenal + H2O + NAD(+) = 2 H(+) + NADH + neurosporaxanthin


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] => 1,6-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: spermine transmembrane transporter activity


name: (1-hydroxycyclohexan-1-yl)acetyl-CoA <=> acetyl-CoA + cyclohexanone


name: 2-oxoglutarate + O2 + tetradecanoyl-CoA <=> 2-hydroxytetradecanoyl-CoA + CO2 + succinate


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Danio rerio)


name: beta-lactose + O2 <=> H2O2 + lactobiono-1,5-lactone


name: PIAS1 SUMOylates SP3 with SUMO1 (Homo sapiens)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Schizosaccharomyces pombe)


name: Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs (Homo sapiens)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Bos taurus)


name: 3'-phosphoadenylyl sulfate + a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine = adenosine 3',5'-bisphosphate + H(+) + N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine


name: DHCR7 reduces 7-dehydroCHOL to CHOL (Sus scrofa)


name: IL1R1 binds IL1R1 inhibitors (Mus musculus)


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Caenorhabditis elegans)


name: Fall Back to Closed Pre-initiation Complex (Caenorhabditis elegans)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Danio rerio)


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + L-lysyl(27)-[histone H3] + 2 succinate


name: SUMOylation of PIAS4 with SUMO1 (Xenopus tropicalis)


name: L-aspartate + NADP(+) => H(+) + iminosuccinate + NADPH


name: H2O + L-arginine + NADP(+) => 5-guanidino-2-oxopentanoate + H(+) + NADPH + NH4(+)


name: FA spontaneously flip-flops back to the matrix side (Homo sapiens)


name: Light stimulates opsin receptors (Canis familiaris)


name: 5,6-dihydrouridine(17) in tRNA + NAD(+) => H(+) + NADH + uridine(17) in tRNA


name: Dephosphorylation of p107 (RBL1) by PP2A (Dictyostelium discoideum)


name: oxoglutarate dehydrogenase (NADP+) activity


name: Separation of elongating transcript from template (Mus musculus)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate <=> 13-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-aminocyclopropane-1-carboxylate + H2O <=> 2-oxobutanoate + NH4(+)


name: Cleavage of factor B to form classical C3 convertase  (Gallus gallus)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Homo sapiens)


name: a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out) => a quinol + 2 Fe(III)-[cytochrome c](out)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Homo sapiens)


name: a bacteriochlorophyllide c + H(+) + S-adenosyl-L-homocysteine => a bacteriochlorophyllide d + S-adenosyl-L-methionine


name: IMPDH tetramers binds IMPDH inhibitors (Xenopus tropicalis)


name: (R)-octopamine => (4-hydroxyphenyl)acetaldehyde + NH4(+)


name: 4-acetamidobutanal + H2O + NAD(+) = 4-acetamidobutanoate + 2 H(+) + NADH


name: (2E,6E)-farnesyl diphosphate + H2O => 7-epi-alpha-eudesmol + diphosphate


name: Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions (Sus scrofa)


name: EFNBs bind SFKs (Caenorhabditis elegans)


name: AKR1B15 reduces EST17b to E1 (Danio rerio)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: UDP-alpha-D-glucuronate(out) + UDP-N-acetyl-alpha-D-galactosamine(in) = UDP-alpha-D-glucuronate(in) + UDP-N-acetyl-alpha-D-galactosamine(out)


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + a ribonucleoside 5'-triphosphate = a 5'-end NTP-ribonucleotide-RNA + AMP + H(+)


name: UBA1 adenylates ubiquitin in the nucleoplasm (Caenorhabditis elegans)


name: glycyl-L-glutamine(out) + H(+)(out) <=> glycyl-L-glutamine(in) + H(+)(in)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)


name: H2O2 + N-acetyl-D-glucosamino-1,5-lactone => N-acetyl-D-glucosamine + O2


name: Interaction of integrin alphaVbeta3 with Tenascin (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Gallus gallus)


name: "phenylalanine aminomutase (L-beta-phenylalanine forming)"


name: a 1-acyl-sn-glycero-3-phosphate + tetradecanoyl-CoA => a 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)


name: [phosphate](n) + D-glucose => [phosphate](n-1) + D-glucose 6-phosphate + H(+)


name: E2F6 forms the PRC1L4 complex (Rattus norvegicus)


name: Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)


name: Protonated weak acid translocates across the plasma membrane (Homo sapiens)


name: hydrogen cyanide + nonanal => (2S)-2-hydroxydecanenitrile


name: sphing-4-enine + tetracosenoyl-CoA = CoA + H(+) + N-(tetracosenoyl)-sphing-4-enine


name: Cleavage and polyadenylation of Intronless Pre-mRNA (Mus musculus)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + NAD(+) <=> androst-4-ene-3,11,17-trione + H(+) + NADH


name: acetyl phosphate + L-lysine <=> H(+) + N(6)-acetyl-L-lysine + phosphate


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Sus scrofa)


name: biliverdin IXalpha + 4 H(+) + 2 reduced 2[4Fe-4S]-[ferredoxin] => (3Z)-phycoerythrobilin + 2 oxidized 2[4Fe-4S]-[ferredoxin]


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: 3-hydroxypropyl isothiocyanate + sulfate => (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate


name: (8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O <=> (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: p-S216-CDC25C translocates to the cytosol (Canis familiaris)


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H2O <=> 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + H(+) + phosphate


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA


name: NH4(+) + pyruvate + S-sulfanyl-L-cysteine => H2O + L-cystine


name: Relocalization of nuclearly localized Cyclin D1 to the cytoplasm (Drosophila melanogaster)


name: NFE2L2 dependent CCL2 expression (Homo sapiens)


name: 1D-myo-inositol 1,2,3,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,3-trisphosphate + phosphate


name: GDP-alpha-D-rhamnose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH


name: Ragulator binds Rag dimers (Xenopus tropicalis)


name: Proteasomal cleavage of substrate (Sus scrofa)


name: a ubiquinol + acetaldehyde => a ubiquinone + ethanol


name: 3-dehydrocarnitine + acetyl-CoA => 3-dehydrocarnityl-CoA + acetate


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Canis familiaris)


name: MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix (Gallus gallus)


name: DPP4 binds DPP4 inhibitors (Schizosaccharomyces pombe)


name: (9Z)-octadecenoyl-[ACP] + H2O <=> (9Z)-octadecenoate + H(+) + holo-[ACP]


name: an acyl-CoA(out) + ATP + H2O => ADP + an acyl-CoA(in) + H(+) + phosphate


name: (4S)-4-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA => (2S)-2-methylbutanoyl-CoA + H(+) + malonyl-[ACP]


name: NKG2D homodimer interacting with ligands (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-(4R)-hydroxysphinganine = a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine


name: H(+) + NADPH + nonanal => NADP(+) + nonan-1-ol


name: H(+)(out) + L-arabinose(out) => H(+)(in) + L-arabinose(in)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O => (9Z,12Z)-octadecadienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: 2-oxoglutarate + neomycin C => 6'''-deamino-6'''-oxoneomycin C + L-glutamate


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Canis familiaris)


name: NAD(+) + pregnan-21-ol => H(+) + NADH + pregnan-21-al


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Caenorhabditis elegans)


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Rattus norvegicus)


name: PIAS1 SUMOylates SP3 with SUMO1 (Gallus gallus)


name: a 2,3-saturated acyl-CoA + NADP(+) => a (2E)-enoyl-CoA + H(+) + NADPH


name: RIP1 facilitates IKK complex phosphorylation (Homo sapiens)


name: CHUK, IKBKB phosphorylate CYLD at S418 (Mus musculus)


name: [protein]-C-terminal Gly-Gly-AMP + diphosphate => [protein]-C-terminal Gly-Gly + ATP + H(+)


name: OCT3 mediates renal clearance of organic cations (Caenorhabditis elegans)


name: atROL binds RBP1 to form RBP1:atROL (Bos taurus)


name: CUL9:RBX1 ubiquitinates BIRC5 (Xenopus tropicalis)


name: 17-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Canis familiaris)


name: alpha-L-arabinopyanose + NAD(+) <=> H(+) + L-arabinono-1,4-lactone + NADH


name: SESN1,2,3 bind overoxidized PRDX1 (Caenorhabditis elegans)


name: Expression of DDIT3 (CHOP, GADD153) in response to unfolded protein (Homo sapiens)


name: ABCG4 may mediate cholesterol efflux (Saccharomyces cerevisiae)


name: (3R,4R)-3,4-dihydroxy-3,4-dihydrobenzoate + pyruvate => chorismate + H2O


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Bos taurus)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Bos taurus)


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Gallus gallus)


name: Phosphorylated LEP:LEPR:JAK2:SH2B1 Binds IRS1/2 (Homo sapiens)


name: NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA => a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Mus musculus)


name: eicosanoyl-CoA + FAD + H(+) <=> (2E)-eicosenoyl-CoA + FADH2


name: OCT3 mediates renal uptake of organic cations (Drosophila melanogaster)


name: D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] <=> D-mannose 6-phosphate(in) + L-histidyl-[protein]


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Canis familiaris)


name: KHK dimer phosphorylates Fru to Fru 1-P (Mus musculus)


name: Trafficking of GluR2-containing AMPA receptors to synapse (Homo sapiens)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Drosophila melanogaster)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Caenorhabditis elegans)


name: blasticidin S + H(+) + H2O => deaminohydroxyblasticidin S + NH4(+)


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)


name: (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate + H2O = (R)-glycerate + alpha-D-mannose 6-phosphate


name: methanol + o-quinone methide <=> hydroxyclavatol methyl ether


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Sus scrofa)


name: 2'-deoxyxanthosine + NH4(+) => 2'-deoxyguanosine + H(+) + H2O


name: CBL ubiquitinates FRS2 and FGFR4 (Mus musculus)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Xenopus tropicalis)


name: granulocyte macrophage colony-stimulating factor receptor activity


name: Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure (Xenopus tropicalis)


name: PAK1 binds RAC1:GTP (Xenopus tropicalis)


name: 2-epi-5-epi-valiolone + phosphate => D-sedoheptulose 7-phosphate


name: [thioredoxin]-dithiol + arsenic triglutathione + 2 H2O + S-adenosyl-L-methionine => [thioredoxin]-disulfide + 3 glutathione + H(+) + methylarsonous acid + S-adenosyl-L-homocysteine


name: Autoglucosylation of GYG2 complexed with GYS2-b (Canis familiaris)


name: 3 a menaquinone(in) + 2 H2O(out) + NH4(+)(out) => 3 a menaquinol(in) + 2 H(+)(out) + nitrite(out)


name: L-cystine transmembrane transporter activity


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Homo sapiens)


name: NPM2 and HIRA bind p-S9-PRM1:dsDNA (Homo sapiens)


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Bos taurus)


name: Beclin-1 complex phosphorylates PtdIns (Gallus gallus)


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Plasmodium falciparum)


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Schizosaccharomyces pombe)


name: a 3alpha-hydroxy bile acid CoA + NAD(+) = a 3-oxo bile acid CoA + H(+) + NADH


name: Basigin binds Matrix metalloproteinase-1 (Caenorhabditis elegans)


name: CBL neddylates TGFBR2 (Rattus norvegicus)


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP(+) => 4alpha-methyl-5alpha-cholest-7-en-3-one + H(+) + NADPH


name: PROT mediates L-proline uptake (Mus musculus)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Bos taurus)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O <=> an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + N-acetyl-D-galactosamine


name: Pink1 is recruited from the cytoplasm to the mitochondria (Rattus norvegicus)


name: CANX dissociates from IL27:EBI3 (Rattus norvegicus)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Gallus gallus)


name: Phosphorylation of MEK4 by MEKK1 (Mus musculus)


name: quercetin 3-sophoroside 7-O-rhamnosyltransferase activity


name: (R)-mandelonitrile => benzaldehyde + hydrogen cyanide


name: 1-naphthaleneacetamide + H2O => 1-naphthaleneacetate + NH4(+)


name: ergosterol + L-aspartyl-tRNA(Asp) => 1-(ergostan-3beta-yl)-L-aspartate + tRNA(Asp)


name: Translocation of PDGF from ER to Golgi (Danio rerio)


name: H(+) + NADPH + progesterone = 5beta-pregnan-3,20-dione + NADP(+)


name: Androgens binds AR (in the HSP90 chaperone complex) (Bos taurus)


name: aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine => H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate


name: CHRM4 binds CHRM4 antagonists (Gallus gallus)


name: 3,4-dihydroxyphenylacetate + CoA + H(+) => 3,4-dihydroxyphenylacetyl-CoA + H2O


name: PA is converted to CDP-DAG by CDS1 (Xenopus tropicalis)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Canis familiaris)


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Mus musculus)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Sus scrofa)


name: CRK binds BCAR1 and or PXN (Homo sapiens)


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + ATP + CoA => (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoyl-CoA + AMP + diphosphate


name: Joining of adjacent Okazaki fragments (Schizosaccharomyces pombe)


name: SOCS3 binds activated PTK6 (Danio rerio)


name: Secretion of SOD3 (Saccharomyces cerevisiae)


name: MAPK6 is degraded by the 26S proteasome (Danio rerio)


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Danio rerio)


name: E1 mediated ubiquitin activation (Homo sapiens)


name: SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids (Drosophila melanogaster)


name: Nuclear translocation of p38 MAPK (Homo sapiens)


name: 3,4-dihydrocoumarin + H2O <=> 3-(2-hydroxyphenyl)propanoate + H(+)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Canis familiaris)


name: taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Sus scrofa)


name: CYP1A2 hydroxylates AFB1 to AFM1 (Homo sapiens)


name: 3-hydroxy-2-methylpyridine-5-carboxylate + NADH + O2 => 2-(acetamidomethylene)succinate + NAD(+)


name: IDS hydrolyses Heparan sulfate chain(5) (Drosophila melanogaster)


name: L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: PARK2 autoubiquitinates (Dictyostelium discoideum)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Mus musculus)


name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Dictyostelium discoideum)


name: Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)


name: 1-octadecanoyl-sn-glycero-3-phosphate + CoA => octadecanoyl-CoA + sn-glycerol 3-phosphate


name: TCF:Beta-catenin binds SOX proteins (Bos taurus)


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Canis familiaris)


name: (9Z,12Z,15Z)-octadecatrienamide + H2O <=> (9Z,12Z,15Z)-octadecatrienoate + NH4(+)


name: LAM translocates from the cell wall to the plasma membrane (Homo sapiens)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Mus musculus)


name: ARSA removes sulfate from SM3 (Canis familiaris)


name: Activation of p38 MAPK (Drosophila melanogaster)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Bos taurus)


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Bos taurus)


name: 2-glutathionyl-2-methylbut-3-enal + H2O + NAD(+) = 2-glutathionyl-2-methylbut-3-enoate + 2 H(+) + NADH


name: D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H2O <=> D-glycero-beta-D-manno-heptose 1-phosphate + phosphate


name: adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine


name: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-4-hydroxyretinol + H2O + 2 oxidized [adrenodoxin]


name: [(2->6)-alpha-D-glucosyl-(1->4)-N,7-O-diacetyl-alpha-D-neuraminosyl](n) + n CoA => [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Bos taurus)


name: (-)-4'-desmethyl-deoxypodophyllotoxin + formaldehyde + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (-)-deoxypodophyllotoxin + O2 + reduced [NADPH--hemoprotein reductase]


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Xenopus tropicalis)


name: 2-oxoglutarate + L-asparaginyl-[protein] + O2 = (3S)-3-hydroxy-L-asparaginyl-[protein] + CO2 + succinate


name: Cleavage of DFF45 (224) by caspase-3 (Canis familiaris)


name: H2O + pravastatin lactone = H(+) + pravastatin


name: STRA6 transports atROL from extracellular region to cytosol (Bos taurus)


name: CoA + H(+) + phenylglyoxylate => H2O + phenylglyoxylyl-CoA


name: a (3R)-hydroxyacyl-[ACP] + L-ornithine <=> a lyso-ornithine lipid + H(+) + holo-[ACP]


name: 2-oxoglutarate + 3-sulfino-L-alanine => 3-sulfinopyruvate + L-glutamate


name: 7-epi-ent-eudesmane-5,11-diol + diphosphate => (2E,6E)-farnesyl diphosphate + 2 H2O


name: O-methyl gibberellin A34 + S-adenosyl-L-homocysteine => gibberellin A34 + S-adenosyl-L-methionine


name: Formation of FACT complex (Plasmodium falciparum)


name: The acetyl group from acetyl-CoA is transferred to the NAT2 (Danio rerio)


name: USP34 deubiquitinates AXIN1,AXIN2 (Rattus norvegicus)


name: biotin transmembrane transporter activity


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Sus scrofa)


name: ERCC6 binds stalled RNA Pol II (Xenopus tropicalis)


name: EML4 recruits NUDC to mitotic spindle (Rattus norvegicus)


name: Activated protein C cleaves Factor Va intermediate form for Factor Va (Mus musculus)


name: Serum albumin binds 2-lysophosphatidylcholine (Sus scrofa)


name: oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor


name: NTPDase8 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)


name: ATP7A transports cytosolic Cu2+ to extracellular region (Canis familiaris)


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Homo sapiens)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Mus musculus)


name: STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Mus musculus)


name: Active IRS recruits PI3K to the plasma membrane and activates it (Rattus norvegicus)


name: N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: H2O + N-terminal N(alpha)-acetyl-L-cysteinyl-L-glutamyl-[protein] => N-acetyl-L-cysteine + N-terminal L-glutamyl-[protein]


name: (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + chloride + FADH2 + O2 <=> (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: (9Z,12Z)-octadecadienoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA


name: 2,4-dinitrophenyl-S-glutathione(out) + ADP + H(+) + phosphate => 2,4-dinitrophenyl-S-glutathione(in) + ATP + H2O


name: HDAC8 deacetylates histones (Bos taurus)


name: (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(2'-(9Z-octadecenoyl)-3'-sn-glycerol) + H2O <=> (9Z)-octadecenoate + (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-sn-glycerol) + H(+)


name: a 5,6-dihydrouridine in RNA + NADP(+) => a uridine in RNA + H(+) + NADPH


name: Trans-autophosphorylation of ERBB2 heterodimers (Gallus gallus)


name: 2 gamma-L-glutamyl-L-cysteine + NADP(+) => bis-gamma-glutamylcystine + H(+) + NADPH


name: Activated FGFR2 phosphorylates FRS2 (Homo sapiens)


name: ERO1B oxidizes P4HB (Caenorhabditis elegans)


name: Formation of eIF2:GDP:eIF2B intermediate (Bos taurus)


name: Association of mTERF with the termination sequence (Mus musculus)


name: Self-ubiquitination of RNF41 (Sus scrofa)


name: AMP(out) + phosphate(in) => AMP(in) + phosphate(out)


name: 5-O-(L-seryl)-dTMP in DNA + H(+) => 5-aminoethoxy-methyl-dUMP in DNA + CO2


name: THG1L transfers GMP to 5' end of tRNA(His) (Homo sapiens)


name: HGSNAT oligomer acetylates Heparan chain(1) (Xenopus tropicalis)


name: FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)


name: O2 + proatranorin II + reduced [NADPH--hemoprotein reductase] => H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin III


name: PANK2 phosphorylates PanK (Mus musculus)


name: a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H2O <=> a lipid X + 2 H(+) + UMP


name: CHRM2 binds CHRM2 antagonists (Mus musculus)


name: Secretion of SOD3 (Dictyostelium discoideum)


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP


name: H(+) + N(2)-methylguanosine(10) in tRNA + S-adenosyl-L-homocysteine => guanosine(10) in tRNA + S-adenosyl-L-methionine


name: holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Homo sapiens)


name: sphinga-(4E,8E)-dienine + tetracosanoyl-CoA <=> CoA + H(+) + N-tetracosanoylsphinga-(4E,8E)-dienine


name: NFE2L2 translocates from cytosol to nucleoplasm (Danio rerio)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Canis familiaris)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Schizosaccharomyces pombe)


name: 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose => 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Sus scrofa)


name: ULK complex translocates to the ER (Homo sapiens)


name: NGF binding to p75NTR inactivates RHOA (Rattus norvegicus)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate = (3R)-3-hydroxy-3-(thiiran-2-yl)propanenitrile + sulfate


name: NCOA1(868-1441) binds PAX3(1-319) (Gallus gallus)


name: H(+)(out) + K(+)(in) + L-aspartate(out) + 3 Na(+)(out) <=> H(+)(in) + K(+)(out) + L-aspartate(in) + 3 Na(+)(in)


name: 10-hydroxydecanoate + NAD(+) <=> 10-oxodecanoate + H(+) + NADH


name: Exocytosis of ficolin-rich granule membrane proteins (Canis familiaris)


name: Activation of TAK1-TAB2 complex (Homo sapiens)


name: ABCB4 transports PC from plasma membrane to extracellular region (Bos taurus)


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-N-(acetyl)-sphing-4-enine


name: Mitochondrial BTD hydrolyses BCTN (Dictyostelium discoideum)


name: FABP5 dissociates from RXRA:PPARD:atRA (Canis familiaris)


name: 2 Fe(III)-[cytochrome cL] + methanol => 2 Fe(II)-[cytochrome cL] + formaldehyde + 2 H(+)


name: 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+) = 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + CO2


name: 2',3'-cyclophospho-CMP + H2O => cytidine 2'-phosphate + H(+)


name: Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA (Homo sapiens)


name: PGG2 is reduced to PGH2 by PTGS2 (Danio rerio)


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Bos taurus)


name: ent-7alpha-hydroxykaur-16-en-19-oate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> gibberellin A12 aldehyde + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Removal of RNA primer and dissociation of RPA and Dna2 (Canis familiaris)


name: dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Homo sapiens)


name: Arachidonic acid is converted to HXA3/B3 by ALOX12 (Danio rerio)


name: CO binds to Cytochrome c oxidase (Gallus gallus)


name: Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Mus musculus)


name: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O


name: 3 a menaquinol(in) + 2 H(+)(out) + nitrite(out) = 3 a menaquinone(in) + 2 H2O(out) + NH4(+)(out)


name: Factor IIa inhibitors (peptide) binds IIa (Mus musculus)


name: 2 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone <=> 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Drosophila melanogaster)


name: 2,2-dihydroxyspirilloxanthin => 2-oxospirilloxanthin + H2O


name: (2E)-geranyl diphosphate <=> (1S,4R)-camphene + diphosphate


name: lutein + O2 <=> (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R,6R)-hydroxy-alpha-ionone


name: 2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O


name: Cytoslic carboxylases translocate to mitochondrial matrix (Xenopus tropicalis)