name: FADH2 + O2 + resorcinol => benzene-1,2,4-triol + FAD + H(+) + H2O


name: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + H(+) + NADPH + O2 = [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + H2O + NADP(+)


name: H(+) + sulfite + UDP-alpha-D-glucose <=> H2O + UDP-alpha-D-6-sulfoquinovose


name: CYP19A1 hydroxylates ANDST to E1 (Mus musculus)


name: H(+) + 2 H2O + porphobilinogen => 2 5-aminolevulinate


name: HuR binds mRNAs in the nucleus (Sus scrofa)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Gallus gallus)


name: Recruitment of IRF3 to activated ZBP1:TBK1 (Homo sapiens)


name: 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Gallus gallus)


name: H(+) + NADPH + tetradecanal => NADP(+) + tetradecan-1-ol


name: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + phosphate


name: GAA hydrolyzes lysosomal glycogen (Sus scrofa)


name: Fall Back to Closed Pre-initiation Complex (Mus musculus)


name: Activation of Rap1 by cytosolic GEFs (Saccharomyces cerevisiae)


name: inulobiose = alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride + H2O


name: L-histidyl-[protein] + S-adenosyl-L-methionine => H(+) + N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine


name: 2 3-phenylpyruvate + 2 ATP = 2 AMP + 2 diphosphate + H(+) + polyporic acid


name: GDIs block activation of RHOC (Canis familiaris)


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NAD(+) = (2S)-2-acetolactate + H(+) + NADH


name: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Gallus gallus)


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Rattus norvegicus)


name: RHOB binds effectors at the plasma membrane (Rattus norvegicus)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Gallus gallus)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Homo sapiens)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Schizosaccharomyces pombe)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Mus musculus)


name: acetyl-CoA + benzyl alcohol = benzyl acetate + CoA


name: BCKDK phosphorylates BCKDH (Homo sapiens)


name: H(+) + NADH + O2 + toralactone <=> 1-(3,4,5-trihydroxy-7-methoxynaphthalen-2-yl)propan-2-one + CO2 + NAD(+)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + GDP-beta-L-fucose => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc derivative + GDP + H(+)


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine => 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O


name: D-threitol + NAD(+) <=> D-erythrulose + H(+) + NADH


name: 1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: gamma-L-glutamyl-butirosin B + H(+) + holo-[BtrI ACP] => 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + ribostamycin


name: 4-hydoxytryptamine 4-phosphate + 2 S-adenosyl-L-methionine = 2 H(+) + psilocybin + 2 S-adenosyl-L-homocysteine


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Drosophila melanogaster)


name: SLC6A15-mediated amino acid uptake (Rattus norvegicus)


name: S-adenosyl-L-methionine + uroporphyrinogen III = H(+) + precorrin-1 + S-adenosyl-L-homocysteine


name: JAK1 binds IL4R in IL13-bound IL13R type II (Canis familiaris)


name: [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate => [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine


name: FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 (Homo sapiens)


name: 2-methylpropanoate + ATP + CoA <=> 2-methylpropanoyl-CoA + AMP + diphosphate


name: "Phosphotransferases with a carboxy group as acceptor"


name: RUNX1 binds the SWI/SNF complex (Gallus gallus)


name: nitrate reductase activity involved in anaerobic electron transport chain


name: ALOX15 oxidises 17(S)-Hp-DHA to PDX (Rattus norvegicus)


name: ALPK1 phosphorylates TIFA (Mus musculus)


name: H2O2 + phenazine-1,6-dicarboxylate => 5,10-dihydrophenazine-1,6-dicarboxylate + O2


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Gallus gallus)


name: 1-phospho-alpha-D-glucuronate + H(+) + UTP <=> diphosphate + UDP-alpha-D-glucuronate


name: NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 (Homo sapiens)


name: a dolichyl beta-D-glucosyl phosphate + chenodeoxycholate <=> a dolichyl phosphate + beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H(+)


name: (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate


name: Apelin receptor binds to apelin (Gallus gallus)


name: Activation of ISG15 by UBA7 E1 ligase (Homo sapiens)


name: ADP + H(+) + O-phospho-L-seryl-[Fas-activated protein] => ATP + L-seryl-[Fas-activated protein]


name: H2O + N(2)-benzoyl-D-arginine-4-nitroanilide <=> 4-nitroaniline + H(+) + N(2)-benzoyl-D-arginine


name: TNF-α:TNFR1 binds NSMAF (Rattus norvegicus)


name: 2-methylfumaryl-CoA + succinate => mesaconate + succinyl-CoA


name: malonyl-[ACP] + N(6)-biotinyl-L-lysyl-[protein] <=> acetyl-[ACP] + N(6)-carboxybiotinyl-L-lysyl-[protein]


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Gallus gallus)


name: LARG activation by G alpha 12/13 (Sus scrofa)


name: glutathione disulfide + 2 H2O => 2 glutathione + H2O2


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + acetyl-CoA => 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CoA


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Homo sapiens)


name: FAHD1:Zn2+ dimer hydrolyses OA to PYR (Drosophila melanogaster)


name: 2 (3R)-hydroxydecanoyl-[ACP] + H2O => (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + H(+) + 2 holo-[ACP]


name: CDC42 binds effectors at the ER membrane (Canis familiaris)


name: 3-(4-hydroxyphenyl)pyruvate + O2 <=> CO2 + homogentisate


name: chorismate + NH4(+) = 4-amino-4-deoxychorismate + H2O


name: EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Drosophila melanogaster)


name: 2-(dihydroxymethyl)-5-formylfuran + O2 = 2-carboxy-5-formylfuran + H(+) + H2O2


name: 2-oxoglutarate + butyl sulfate + O2 <=> butanal + CO2 + H(+) + succinate + sulfate


name: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Rattus norvegicus)


name: EPOR binds EPOR agonists (Xenopus tropicalis)


name: H2O + N-(carboxymethyl)-D-alanine + NAD(+) => glycine + H(+) + NADH + pyruvate


name: FMN + H(+) + oxidized coenzyme F420-0 => dehydro coenzyme F420-0 + FMNH2


name: Autophosphorylation of LYN kinase (Caenorhabditis elegans)


name: PRKAA2 regulated nuclear export of NFE2L2 (Rattus norvegicus)


name: 2-oxooctadecanoate + H2O2 => 2-hydroxyoctadecanoate + O2


name: imaginal disc growth factor receptor binding


name: L-glutamate + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose => 2-oxoglutarate + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine


name: RBBP7 binds histone H3 (Plasmodium falciparum)


name: ATP + daunorubicin(in) + H2O = ADP + daunorubicin(out) + H(+) + phosphate


name: 5-(methylsulfanyl)-D-ribose + ATP <=> ADP + H(+) + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: BCMO1:Fe2+ cleaves betaC to atRAL (Rattus norvegicus)


name: (6aR,11aR)-3,9-dihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-glucose(out) + Na(+)(out) = D-glucose(in) + Na(+)(in)


name: (3R)-3-hydroxypentanoyl-CoA + H2O <=> (3R)-3-hydroxypentanoate + CoA + H(+)


name: The high affinity receptor complex binds to G-protein (Xenopus tropicalis)


name: uridine in snRNA = pseudouridine in snRNA


name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Mus musculus)


name: 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate => 2-oxoglutarate + L-histidinol phosphate


name: RHOD binds effectors at the mitochondrial outer membrane (Drosophila melanogaster)


name: SUMOylation of RAD52 with SUMO1 (Schizosaccharomyces pombe)


name: 6-sulfo-alpha-D-quinovose + a 1,2-diacyl-sn-glycerol => a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H2O


name: butanoyl-CoA + H(+) + NADH => butanal + CoA + NAD(+)


name: farnesoic acid O-methyltransferase activity


name: Secretion and activation of the latent large complex of TGF-beta-1 (Caenorhabditis elegans)


name: (2R)-hydroxybutanoyl-CoA => (2E)-butenoyl-CoA + H2O


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Canis familiaris)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + 2 glutathione <=> (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: p-6Y-SYK phosphorylates BLNK (SLP65) (Canis familiaris)


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Xenopus tropicalis)


name: deoxycholoyl-CoA + NAD(+) => 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + H(+) + NADH


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine <=> di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP


name: GUCY2C trimer binds GUCA2A,B (Gallus gallus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Schizosaccharomyces pombe)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Xenopus tropicalis)


name: ATP + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine => 6-O-phospho-N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine + ADP + H(+)


name: UDP-beta-L-arabinofuranose(in) + UMP(out) <=> UDP-beta-L-arabinofuranose(out) + UMP(in)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Rattus norvegicus)


name: H(+) + L-proline betaine + NADPH + O2 => formaldehyde + H2O + N-methyl-L-proline + NADP(+)


name: H2O + N(6)-tetradecanoyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: ADA catalyzes the deamination of (deoxy)adenosine (Dictyostelium discoideum)


name: (9Z,12Z)-octadecadienoate + O2 => (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate


name: SENP1,2,5 proteolytically process SUMO1 (Homo sapiens)


name: VAV2 is a GEF for Rho/Rac family kinases (Canis familiaris)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Xenopus tropicalis)


name: acetyl-CoA + chloramphenicol <=> chloramphenicol 3-acetate + CoA


name: (1R,2R)-12-hydroxyjasmonate + CO2 + succinate => 2-oxoglutarate + jasmonate + O2


name: H2O + N-tetracosanoyl-sphing-4-enine => sphing-4-enine + tetracosanoate


name: A + all-trans-7,8-dihydroretinol <=> AH2 + all-trans-retinol


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate


name: transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential


name: 2-deoxy-scyllo-inosamine + 2-oxoglutaramate => 2-deoxy-L-scyllo-inosose + L-glutamine


name: BP230 is recruited to the hemidesmosome (Homo sapiens)


name: (2E)-geranyl diphosphate <=> diphosphate + gamma-terpinene


name: allantoate + H2O => (S)-ureidoglycolate + urea


name: DDAH1,2 hydrolyses ADMA to DMA and L-Cit (Rattus norvegicus)


name: (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O => (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: AH2 + L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + A + H(+) + L-methionine


name: Receptor-mediated uptake of HA (Homo sapiens)


name: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) <=> benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH


name: (3S)-hydroxy-(5Z-tetradecenoyl)-CoA => (2E,5Z)-tetradecadienoyl-CoA + H2O


name: (9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-corytuberine + S-adenosyl-L-methionine <=> magnoflorine + S-adenosyl-L-homocysteine


name: (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) => 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + NADH


name: ferric-vibriobactin transmembrane transporter activity


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Xenopus tropicalis)


name: Aquaporin-9 passively transports glycerol into cell (Mus musculus)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Xenopus tropicalis)


name: PON1,3 hydrolyse ATVL to ATV (Danio rerio)


name: Formation of lysyl-pyrrole cross-links (Gallus gallus)


name: ANKLE2 is deacetylated by SIRT2 (Drosophila melanogaster)


name: atranorin + S-adenosyl-L-homocysteine => proatranorin III + S-adenosyl-L-methionine


name: Necl-2:Nectin 3 trans heterodimer interaction (Canis familiaris)


name: p-S225-SPHK1 localizes to cytosol (Schizosaccharomyces pombe)


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Rattus norvegicus)


name: SCF-FBXL18 ubiquitinates FBXL7 (Rattus norvegicus)


name: TNF-α is cleaved by ADAM17 (TACE) (Bos taurus)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GM1b (d18:1(4E)) + CMP + H(+)


name: H2O + leukotriene D4 => glycine + leukotriene E4


name: N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1248) in human 18S rRNA + S-methyl-5'-thioadenosine


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Dictyostelium discoideum)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Rattus norvegicus)


name: complement component C1q complex binding


name: Active ALK phosphorylates JAK3 (Bos taurus)


name: "N-terminal methionine N(alpha)-acetyltransferase NatB"


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = a 2-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: PRKAA2 phosphorylates nuclear NFE2L2 (Sus scrofa)


name: AP1G2 binds HGS and CHMP2A (Homo sapiens)


name: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H(+) + phosphate


name: MAP2K1 binds MAPK3 (Caenorhabditis elegans)


name: Transfer of ISG15 from E1 to E2 (UBCH8) (Dictyostelium discoideum)


name: IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Rattus norvegicus)


name: Dimerization of STATs downstream of KIT mutants (Homo sapiens)


name: TPI1 isomerizes GA3P to DHAP (Bos taurus)


name: H2O + N-octanoylanthranilate => anthranilate + H(+) + octanoate


name: A + decanedioyl-CoA <=> (2E)-decenedioyl-CoA + AH2


name: PTK6 binds ARAP1 (Caenorhabditis elegans)


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Sus scrofa)


name: H(+) + hispidin + NADPH + O2 = 3-hydroxyhispidin + H2O + NADP(+)


name: low-affinity zinc ion transmembrane transporter activity


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Homo sapiens)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Dictyostelium discoideum)


name: ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA (Danio rerio)


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Mus musculus)


name: Cdc45 associates with the pre-replicative complex at the origin (Mus musculus)


name: abieta-7,13-dien-18-al + O2 + reduced [NADPH--hemoprotein reductase] => abieta-7,13-dien-18-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate + H2O = (+)-corvol ether B + diphosphate


name: RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Mus musculus)


name: crizotinib-resistant ALK mutants don't bind crizotinib (Homo sapiens)


name: 2 H(+) + malonyl-CoA + methylmalonyl-CoA + octadecanoyl-CoA <=> 4-hydroxy-5-methyl-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA


name: L-alanine(out) + L-glutamine(in) + Na(+)(out) <=> L-alanine(in) + L-glutamine(out) + Na(+)(in)


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Xenopus tropicalis)


name: Defective CYP2R1 does not 25-hydroxylate vitamin D (Homo sapiens)


name: RAC2 GAPs stimulate RAC2 GTPase activity (Homo sapiens)


name: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine


name: Coat Assembly (Saccharomyces cerevisiae)


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Plasmodium falciparum)


name: KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Homo sapiens)


name: GTP + oxaloacetate <=> CO2 + GDP + phosphoenolpyruvate


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Danio rerio)


name: Formation of lysyl-pyrrole cross-links (Xenopus tropicalis)


name: Release of 40S and 60S subunits from the 80S ribosome  (Gallus gallus)


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Caenorhabditis elegans)


name: Association of DFF40 with DFF45 (Drosophila melanogaster)


name: SKI complexes with the Smad complex, suppressing BMP2 signalling (Mus musculus)


name: ATP + gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate <=> ADP + H(+) + L-glutamyl-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + phosphate


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Homo sapiens)


name: PCK1 phosphorylates OA to yield PEP (Caenorhabditis elegans)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Mus musculus)


name: 2-oxoglutarate + a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in U6 snRNA + O2 => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in U6 snRNA + CO2 + formaldehyde + succinate


name: Assembly of telomerase RNP (Gallus gallus)


name: Exocytosis of azurophil granule lumen proteins (Dictyostelium discoideum)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Caenorhabditis elegans)


name: GDP-alpha-D-mannuronate + 3 H(+) + 2 NADH => GDP-alpha-D-mannose + H2O + 2 NAD(+)


name: CMKLR1 binds Resolvin E1 (Xenopus tropicalis)


name: (S)-6-hydroxynicotine + H2O + O2 => 6-hydroxypseudooxynicotine + H2O2


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a ribonucleotide in U6 snRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in U6 snRNA + H(+) + S-adenosyl-L-homocysteine


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Mus musculus)


name: Activation of Ca impermeable AMPA receptors (Rattus norvegicus)


name: dibenzothiophene 5,5-dioxide + 2 FMN + 2 H(+) + 2 H2O => dibenzothiophene + 2 FMNH2 + 2 O2


name: NEIL2 cleaves 5-OHU from damaged DNA (Homo sapiens)


name: Formation of FACT complex (Xenopus tropicalis)


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Saccharomyces cerevisiae)


name: glyphosate + H2O + O2 => aminomethylphosphonate + glyoxylate + H(+) + H2O2


name: RHOJ binds effectors at the plasma membrane (Homo sapiens)


name: Release of 40S and 60S subunits from the 80S ribosome  (Rattus norvegicus)


name: IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Bos taurus)


name: a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate => 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2


name: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD(+) => a long-chain 3-oxo-fatty acyl-CoA + H(+) + NADH


name: D-alanyl-5'-AMP + holo-[D-alanyl-carrier protein] => AMP + D-alanyl-[D-alanyl-carrier protein] + H(+)


name: a 3-(acyloxy)acyl derivative of bacterial toxin + H2O <=> 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)


name: SCD5 desaturates ST-CoA to OLE-CoA (Plasmodium falciparum)


name: galactitol 1-phosphate + NAD(+) = H(+) + keto-L-tagatose 6-phosphate + NADH


name: Orexin 1 receptor can bind orexin-A neuropeptide (Canis familiaris)


name: (11Z)-hexadecenoyl-CoA + AH2 + O2 = (10E,12Z)-hexadecadienoyl-CoA + A + 2 H2O


name: 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin => 2-oxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecenyl)-glycerol => 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: 1,2-dioctanoyl-3-O-beta-D-galactosyl-sn-glycerol + H2O = 2-octanoyl-3-O-beta-D-galactosyl-sn-glycerol + H(+) + octanoate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: XIAP dissociates from ub-TLE (Homo sapiens)


name: ILF3 binds PKR (Drosophila melanogaster)


name: MAP kinase tyrosine phosphatase activity


name: [(2E,6E,10E)-geranylgeranyl]-L-cysteine + H2O + O2 => (2E,6E,10E)-geranylgeranial + H2O2 + L-cysteine


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)


name: (R,S)-butane-2,3-diol + NAD(+) => (R)-acetoin + H(+) + NADH


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Rattus norvegicus)


name: Active calmodulin binds CAMK2 (Drosophila melanogaster)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Bos taurus)


name: apelin-17 + H2O => apelin-16 + L-phenylalanine


name: a nucleoside 5'-phosphate + H2O => a nucleoside + phosphate


name: Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA (Homo sapiens)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Drosophila melanogaster)


name: Cleavage of uracil by UNG glycosylase (Dictyostelium discoideum)


name: Phosphorylation of IL2RB Y338 enables SHC recruitment (Mus musculus)


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Drosophila melanogaster)


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Bos taurus)


name: SCF(SKP2) complex binds RUNX2 (Canis familiaris)


name: ATP + H2O + L-aspartate(out) <=> ADP + H(+) + L-aspartate(in) + phosphate


name: CHRM4 binds CHRM4 antagonists (Homo sapiens)


name: SALM4 binds flotillin-1 (Rattus norvegicus)


name: SORD tetramer oxidizes xylitol to D-xylulose (Schizosaccharomyces pombe)


name: SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Xenopus tropicalis)


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Danio rerio)


name: NADP(+) + ursodeoxycholate => 7-oxolithocholate + H(+) + NADPH


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H(+) + NADH <=> 4-pyridoxate + NAD(+)


name: Exocytosis of azurophil granule lumen proteins (Homo sapiens)


name: L-arginyl-[protein] + 2 S-adenosyl-L-methionine => 2 H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine


name: 6-deoxy-6-sulfo-D-gluconate <=> 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O


name: an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose => a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Drosophila melanogaster)


name: 3-sulfanyl-1-pentanol + NH4(+) + pyruvate => 3-sulfanylpentan-1-ol-L-cysteine + H2O


name: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose (Xenopus tropicalis)


name: TP53 binds the complex of JMY, EP300 and TTC5 (Bos taurus)


name: a ganglioside GP1c (d18:1(4E)) + CMP + H(+) => a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: Phosphorylation and activation of VAV (Drosophila melanogaster)


name: TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Canis familiaris)


name: Cleaved fibrinogen products bind TLR4:LY96 (Bos taurus)


name: USP10,USP24,USP42 deubiquitinate TP53 (Homo sapiens)


name: (+)-(E)-beta-caryophyllene + H2O = (+)-caryolan-1-ol


name: GPR35 binds kynurenic acid (Caenorhabditis elegans)


name: 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Danio rerio)


name: 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + H(+) + S-adenosyl-L-homocysteine


name: kaempferol + S-adenosyl-L-methionine = H(+) + kaempferide + S-adenosyl-L-homocysteine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: a (3R)-hydroxyacyl-[ACP] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose => a UDP-2-acetamido-3-{[(3R)-3-hydroxyacyl]amino}-2,3-dideoxy-alpha-D-glucopyranose + H(+) + holo-[ACP]


name: tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate (Rattus norvegicus)


name: MSH2:MSH3 binds insertion/deletion loop of 2 bases or more (Bos taurus)


name: Release of L-Glutamate at the synapse (Canis familiaris)


name: MigFilin associates with Filamin and F-actin (Mus musculus)


name: ISGylation of protein phosphatase 1 beta (PP2CB) (Sus scrofa)


name: an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => an (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: H2O + NAD(+) + nitrous oxide <=> H(+) + NADH + 2 nitric oxide


name: an adenosine in mRNA + S-adenosyl-L-methionine = an N(1)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: Fillagrin and keratin intermediate filaments polymerize forming a network (Sus scrofa)


name: HATs and coactivators are recruited to the CTSD gene (Sus scrofa)


name: 2 H(+) + N-(carboxyaminomethyl)urea = CO2 + N-(aminomethyl)urea


name: PTPN11 dephosphorylates RUNX1 (Xenopus tropicalis)


name: p-PKR dimer phosphorylates ILF3:ILF2 (Sus scrofa)


name: Interaction of Tie2 and Shc1 (Canis familiaris)


name: a dicarboxylate + NH4(+) => a monoamide of a dicarboxylate + H2O


name: D-maltose + O2 <=> D-maltobiono-1,5-lactone + H2O2


name: GluN1:GluN2B (GRIN1:GRIN2B) di-heterotetramers bind LIN7:CASK:APBA1, DLG1 and KIF17 (Homo sapiens)


name: p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D (Homo sapiens)


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Caenorhabditis elegans)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose = beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)


name: CaMKK autophosphorylates in the nucleus (Mus musculus)


name: S-(hydroxymethyl)glutathione <=> formaldehyde + glutathione


name: (E)-4-coumaraldehyde + AH2 => (E)-4-coumaroyl alcohol + A


name: (R)-carnitine(out) + O-octanoyl-(R)-carnitine(in) <=> (R)-carnitine(in) + O-octanoyl-(R)-carnitine(out)


name: TRPM4,5 transport extracellular Na+ to cytosol (Homo sapiens)


name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] (Xenopus tropicalis)


name: B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Bos taurus)


name: GLUT1 tetramer binds 4xATP (Gallus gallus)


name: SLC12A3 binds SLC12A3 inhibitors (Canis familiaris)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Bos taurus)


name: ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate


name: SLC2A5 transports fructose from extracellular region to cytosol (Caenorhabditis elegans)


name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)


name: DHFR gene expression is stimulated by E2F1 (Homo sapiens)


name: 2-oxoglutarate + glyoxylate + H(+) <=> 2-hydroxy-3-oxoadipate + CO2


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Canis familiaris)


name: Ligation of DNA at sites of patch replacement (Gallus gallus)


name: p-S585-IL3RB binds 14-3-3 proteins (Gallus gallus)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Homo sapiens)


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Sus scrofa)


name: CPN, CPB2 cleave C3a, C5a (Canis familiaris)


name: Inactivation of LCK by PTPN22 (Canis familiaris)


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Homo sapiens)


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Homo sapiens)


name: AMP + chenodeoxycholoyl-CoA + diphosphate => ATP + chenodeoxycholate + CoA


name: Ribosomal scanning  (Plasmodium falciparum)


name: all-trans-retinyl hexadecanoate + CoA => all-trans-retinol + hexadecanoyl-CoA


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Canis familiaris)


name: PARG dePARylates PARP1,PARP2 (Gallus gallus)


name: 3'-phosphoadenylyl sulfate + ADP + H(+) => adenosine 5'-phosphosulfate + ATP


name: IL13 binds IL13RA:TYK2 (Rattus norvegicus)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Saccharomyces cerevisiae)


name: MDH1 oxidizes MAL to OA (Xenopus tropicalis)


name: hexadecanal + NADP(+) = (2E)-hexadecenal + H(+) + NADPH


name: a carboxylate + ATP + CoA => AMP + an acyl-CoA + diphosphate


name: ERBB4 binds NRGs or EGF-like ligands (Gallus gallus)


name: A + dodecanedioyl-CoA <=> (2E)-dodecenedioyl-CoA + AH2


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol => a 1,3-diacyl-sn-glycerol + a monoacyl-sn-glycero-3-phosphocholine


name: codeine + NADP(+) => codeinone + H(+) + NADPH


name: a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Dissociation of cytosolic HSF1:HSP90 complex (Caenorhabditis elegans)


name: 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + nonanedioate


name: pro-beta-NGF homodimer transits to the golgi apparatus (Homo sapiens)


name: 1,8-cineole + diphosphate => (2E)-geranyl diphosphate + H2O


name: 2-oxoglutarate + 3-hydroxy-L-kynurenine => H2O + L-glutamate + xanthurenate


name: N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine => (9Z,12Z,15Z)-octadecatrienamide + glyoxylate


name: Formation of Cyclin A:Cdc2 complexes (Homo sapiens)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Schizosaccharomyces pombe)


name: DSPG and CSPG translocate to the lysosome for degradation (Drosophila melanogaster)


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-4,8-dimethyldeca-4,8-dienoyl-CoA + NAD(+) = (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-4,8-dimethyldeca-4,8-dienoyl-CoA + H(+) + NADH


name: GOT2 dimer deaminates L-Asp (Canis familiaris)


name: adlupulone + diphosphate + H(+) => deoxyadlupulone + dimethylallyl diphosphate


name: Phosphorylation of GAB2 by SFKs (Canis familiaris)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Mus musculus)


name: a ganglioside GD1a + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GD1a + H(+) + UDP


name: SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Mus musculus)


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + a 1-acyl-sn-glycero-3-phosphocholine + H(+)


name: 2-carboxy-5-formylfuran + H2O <=> 2-carboxy-5-(dihydroxymethyl)furan


name: H2O + L-alanyl-L-histidine => L-alanine + L-histidine


name: p-T68-CHEK2 dimerizes (Caenorhabditis elegans)


name: SLC6A18 transports Gly from extracellular region to cytosol (Bos taurus)


name: 1-acyl-2-(9Z,12Z-octadecadienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 1-acyl-2-(9Z,12Z,15Z-octadecatrienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Drosophila melanogaster)


name: a 3',5'-dihydroxyflavanone + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => a 3',5'-unsubstituted flavanone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Rattus norvegicus)


name: Activated FGFR1 phosphorylates SHC1 (Bos taurus)


name: H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline <=> 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Phosphorylated HSL dimer translocates from the cytosol to the lipid particle (Homo sapiens)


name: 2,6-dihydroxypyridine + H(+) + NADH + O2 <=> 2,3,6-trihydroxypyridine + H2O + NAD(+)


name: glycyl-L-lysine(in) + 2 H(+)(in) => glycyl-L-lysine(out) + 2 H(+)(out)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Xenopus tropicalis)


name: glyoxal + L-lysyl-[protein] => N(6)-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein]


name: quercetin + S-adenosyl-L-methionine => H(+) + isorhamnetin + S-adenosyl-L-homocysteine


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Gallus gallus)


name: Beta-defensins 4A and 103 bind CCR2 (Homo sapiens)


name: FUT1,2 transfer fucose to gangliosides (Xenopus tropicalis)


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Danio rerio)


name: LMCD1 binds GATA6, sequestering it (Mus musculus)


name: Recruitment of Dna2 endonuclease (Homo sapiens)


name: SUMOylation of PCNA with SUMO1 (Gallus gallus)


name: ATP + L-glutamate + oxidized coenzyme F420-2 <=> ADP + H(+) + oxidized coenzyme alpha-F420-3 + phosphate


name: (S)-5'-oxoaverantin + 2 H(+) + NADH => (1'S,5'R)-5'-hydroxyaverantin + NAD(+)


name: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) = a quinol + beta-nicotinamide D-riboside


name: ERBB4s80 binds STAT5A (Caenorhabditis elegans)


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Bos taurus)


name: A1 and A3 receptors bind adenosine (Caenorhabditis elegans)


name: AKT phosphorylates FOXO transcription factors (Mus musculus)


name: Loading of PCNA - Sliding Clamp Formation (Mus musculus)


name: cytidine + phosphate = alpha-D-ribose 1-phosphate + cytosine


name: (13E)-labda-7,13-dien-15-yl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphate


name: ADP(out) + dAMP(in) + H(+)(out) <=> ADP(in) + dAMP(out) + H(+)(in)


name: H2O + N-formyl-L-aspartate <=> formate + L-aspartate


name: (2E,6E)-farnesyl diphosphate => (-)-beta-barbatene + diphosphate


name: a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 3'-phosphate + H(+)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Mus musculus)


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Canis familiaris)


name: 3,4-dihydroxyphenylacetate + O2 => 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)


name: GMP + H2O = D-ribose 5-phosphate + guanine


name: phosphotransferase activity, alcohol group as acceptor


name: mutildienyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: neutral L-amino acid:sodium:chloride symporter activity


name: Detection of damage during initiation of DNA synthesis in S-phase (Bos taurus)


name: OAS2 produces oligoadenylates (Homo sapiens)


name: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+)


name: H2O + hexylamine + NAD(+) => H(+) + hexanal + NADH + NH4(+)


name: VD3 translocates from extracellular region to ER membrane (Homo sapiens)


name: PC is converted to PS by PTDSS1 (Sus scrofa)


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Xenopus tropicalis)


name: malonate(out) + sulfate(in) => malonate(in) + sulfate(out)


name: ATP7A transports cytosolic Cu2+ to extracellular region (Sus scrofa)


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Sus scrofa)


name: NTPDase7 hydrolyzes nucleoside triphosphates (Mus musculus)


name: Release of 40S and 60S subunits from the 80S ribosome  (Homo sapiens)


name: H(+) + menadione + NADH <=> menadiol + NAD(+)


name: Raf dimer inhibitors bind RAF heterodimers (Drosophila melanogaster)


name: TXNIP binds reduced thioredoxin (Canis familiaris)


name: H2O + N(4)-acetyl-2'-deoxycytidine = 2'-deoxycytidine + acetate + H(+)


name: 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + NADH => (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+)


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Homo sapiens)


name: H(+) + NADH + pyruvate + taurine => H2O + NAD(+) + tauropine


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR (Rattus norvegicus)


name: 2-oxoglutarate + pyridoxamine 5'-phosphate <=> D-glutamate + pyridoxal 5'-phosphate


name: Tropoelastin forms aggregate globules (Canis familiaris)


name: a fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Sus scrofa)


name: (13Z)-docosenoyl-CoA + H(+) + malonyl-CoA <=> (15Z)-3-oxotetracosenoyl-CoA + CO2 + CoA


name: Syk activation leads to SLP-76 activation (Sus scrofa)


name: dADP(out) + H(+)(out) + phosphate(in) <=> dADP(in) + H(+)(in) + phosphate(out)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Saccharomyces cerevisiae)


name: 2-oxoheptanedioate + acetyl-CoA + H2O = (R)-trihomocitrate + CoA + H(+)


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Rattus norvegicus)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Sus scrofa)


name: H(+) + isopentadecanoyl-CoA + L-serine => 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA


name: ESR-associated SRC autophosphorylates (Danio rerio)


name: 32-oxolanosterol + O2 + reduced [NADPH--hemoprotein reductase] = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Collagen type III degradation by MMP1,8,9,13 (Homo sapiens)


name: (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1R,6S)-isopiperitenol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Sus scrofa)


name: an acyl-CoA + sn-glycerol 3-phosphate => a 2-acyl-sn-glycerol 3-phosphate + CoA


name: alpha-D-glucose 6-phosphate + H2O <=> alpha-D-glucose + phosphate


name: Acyl Ghrelin and C-Ghrelin are secreted (Homo sapiens)


name: 2-hydroxy-2,3-dihydrogenistein => genistein + H(+) + H2O


name: gamma-secretase cleaves EPHB2 (Mus musculus)


name: MTMR14, MTMR3 dephosphorylate PI3P (Xenopus tropicalis)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Dictyostelium discoideum)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: Trimerization of HSF1 in the nucleus (Drosophila melanogaster)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)


name: 7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H(+)


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Mus musculus)


name: peroxisome matrix targeting signal-1 binding


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Gallus gallus)


name: SH mRNA is translated into protein SHt (Homo sapiens)


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Xenopus tropicalis)


name: RdRP binds hRSV nucleocapsid (Homo sapiens)


name: (2E)-tetradecenoyl-CoA + H2O => (3S)-hydroxytetradecanoyl-CoA


name: adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine


name: DNA ligase I ligates single stranded nick in double stranded DNA (Bos taurus)


name: SOX10-dependent POU3F1 gene expression (Homo sapiens)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Caenorhabditis elegans)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Gallus gallus)


name: ABCB1 transports PREDN,PREDL out of hepatic cells (Rattus norvegicus)


name: [(1->3)-beta-D-glucosyl](n) + phosphate => [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: 2-methylpropanoate + CoA + H(+) => 2-methylpropanoyl-CoA + H2O


name: PNPLA5 hydrolyzes TAG (Caenorhabditis elegans)


name: 5,6-dihydrouridine(20) in tRNA + NAD(+) => H(+) + NADH + uridine(20) in tRNA


name: bPIX exchanges GTP for GDP on RAC, activating it (Drosophila melanogaster)


name: intracellular cAMP-activated cation channel activity


name: SLC46A1 transports FOLA from extracellular region to cytosol (Xenopus tropicalis)


name: S-adenosyl-L-methionine + thiocyanate => methyl thiocyanate + S-adenosyl-L-homocysteine


name: ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Homo sapiens)


name: AUF1 binds translation and heat shock proteins (Bos taurus)


name: DeHA hydrolyses to threonate and oxalate (Homo sapiens)


name: ABHD14B hydrolyses PNPB (Rattus norvegicus)


name: 32-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase] => 32-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: ACSF3 ligates CoA-SH to VLCFA (Sus scrofa)


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Caenorhabditis elegans)


name: quillate + UDP-alpha-D-glucose => quillaic acid 28-beta-D-glucoside + UDP


name: RUNX1 binds PRC1 complexes (Rattus norvegicus)


name: Caspase-mediated cleavage of plakophilin-1 (Mus musculus)


name: H2O + mevastatin = H(+) + mevinic carboxylate


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Danio rerio)


name: RHOV binds effectors at the plasma membrane (Danio rerio)


name: ISGylation of host proteins (Dictyostelium discoideum)


name: H2O + N-sulfo-D-glucosamine <=> D-glucosamine + sulfate


name: 2-hydroxymethyl-3-pentylphenol + O2 + reduced [NADPH--hemoprotein reductase] <=> (8S)-annullatin E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E)-tetradecenedioyl-CoA + H2O <=> (3S)-hydroxytetradecanedioyl-CoA


name: 2 Fe(III)-[cytochrome c] + H2O + N2 <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + nitrous oxide


name: HMGB1 binds TLR4:LY96 (Rattus norvegicus)


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Bos taurus)


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Dictyostelium discoideum)


name: PKN1 stimulates association of AR with NCOA2 (Rattus norvegicus)


name: luteolin 4',7-dimethyl ether + S-adenosyl-L-homocysteine => diosmetin + S-adenosyl-L-methionine


name: Release of platelet secretory granule components (Sus scrofa)


name: Ghrelin O-acyltransferase decanoylates Proghrelin (Sus scrofa)


name: Release of platelet cytosolic components (Xenopus tropicalis)


name: (2E)-decenoyl-[ACP] + AMP + diphosphate => (2E)-decenoate + ATP + holo-[ACP]


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Drosophila melanogaster)


name: n H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) => n H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out)


name: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Sus scrofa)


name: ADP + gamma-L-glutamyl-(2S)-2-aminobutanoate + H(+) + phosphate => (2S)-2-aminobutanoate + ATP + L-glutamate


name: Beta-defensins 4A and 103 bind CCR2 (Bos taurus)


name: saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity


name: Autophagosome maturation (Dictyostelium discoideum)


name: 2-methoxy-6-all-trans-decaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoyl-CoA + AMP + diphosphate => 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + ATP + CoA


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-acyl-15-methylhexadecasphing-4-enine => a 1,2-diacyl-sn-glycerol + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine


name: SLC7A10-mediated uptake of small neutral amino acids (Sus scrofa)


name: 3-dehydro-L-gulonate 6-phosphate + ADP + H(+) => 3-dehydro-L-gulonate + ATP


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: Active ALK dimer binds IRS1 (Bos taurus)


name: H(+) + NADH + O2 + propane => H2O + NAD(+) + propan-2-ol


name: PANK2 phosphorylates PanK (Homo sapiens)


name: RvT1-4 translocate from cytosol to extracellular region (Homo sapiens)


name: a 4'-methoxyisoflavone + H(+) + S-adenosyl-L-homocysteine => a 4'-hydroxyisoflavone + S-adenosyl-L-methionine


name: PTGS2 dimer binds PTGS2 inhibitors (Canis familiaris)


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Drosophila melanogaster)


name: ATP + H2O + putrescine(out) = ADP + H(+) + phosphate + putrescine(in)


name: H2O2 + NH4(+) + pyridoxal => H2O + O2 + pyridoxamine


name: AMPK is dephosphorylated (Caenorhabditis elegans)


name: a 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphing-4-enine + H(+) + UDP => a N-(2-hydroxyacyl)sphing-4-enine + UDP-alpha-D-galactose


name: AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Bos taurus)


name: 2,2'-iminodipropanoate + H2O + NAD(+) => H(+) + L-alanine + NADH + pyruvate


name: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Homo sapiens)


name: ATP + H2O + phenol <=> AMP + 2 H(+) + phenyl phosphate + phosphate


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Canis familiaris)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: USP18 deubiquitinates TAK1:TAB1 (Homo sapiens)


name: ethyl (9Z)-octadecenoate + H2O => (9Z)-octadecenoate + ethanol + H(+)


name: 3-oxoheptanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyheptanoyl-[ACP] + NADP(+)


name: CYP51A1 demethylates LNSOL (Homo sapiens)


name: Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Sus scrofa)


name: Formation of the GCN5-ATAC complex (Rattus norvegicus)


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Canis familiaris)


name: H(+) + N,N-dihydroxy-L-tryptophan = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + H2O


name: S1P binds S1PR3 in response to E2 stimulation (Rattus norvegicus)


name: 26S proteasome degrades TP73 polyubiquitinated by ITCH (Sus scrofa)


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol = 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+)


name: GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA (Dictyostelium discoideum)


name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate => D-erythrose 4-phosphate + H2O + phosphoenolpyruvate


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O = (9Z)-octadecenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Danio rerio)


name: Activation of Edited Kainate receptors (Mus musculus)


name: (E)-4-hydroxynon-2-enal + H2O + NAD(+) = (E)-4-hydroxynon-2-enoate + 2 H(+) + NADH


name: H2O + S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] => H(+) + L-cysteinyl-[protein] + lactate


name: 17beta-estradiol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: dalpatein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O = beta-D-apiofuranosyl-(1->6)-D-glucopyranose + dalpatein + H(+)


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Canis familiaris)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Sus scrofa)


name: H(+) + NADPH + norsolorinic acid => (1'S)-averantin + NADP(+)


name: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a <=> 3-deacetyl-3-vinylbacteriochlorophyllide a + H2O


name: Activation of tandem pore domain in a weak inwardly rectifying  K+ channels (Bos taurus)


name: UDP-glucose is oxidised to UDP-glucuronate (Canis familiaris)


name: Internalization of MHC II:Ii clathrin coated vesicle (Mus musculus)


name: H2O + substance P = Gly-L-Leu-L-Met-NH2 + substance P(1-8)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Sus scrofa)


name: Aquaporin-7 passively transports glycerol out of cell (Mus musculus)


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Drosophila melanogaster)


name: 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + hexanoyl-sn-glycero-3-phosphoethanolamine => 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 2-heptanoyl-sn-glycero-3-phosphocholine


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers (Homo sapiens)


name: dolabradiene + O2 + reduced [NADPH--hemoprotein reductase] = 15,16-epoxydolabrene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate (Mus musculus)


name: AP-1 complex stimulates KDM6B transcription (Homo sapiens)


name: (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] <=> (2S)-dihydrotricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylsphinganine => a 1,2-diacyl-sn-glycerol + an N-acylsphinganine-1-phosphocholine


name: a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine => H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: Connexin oligomerization in endoplasmic reticulum membrane (Xenopus tropicalis)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Dictyostelium discoideum)


name: H2O + isopimara-7,15-dienal + NADP(+) => 2 H(+) + isopimarate + NADPH


name: 3-(3,4-dihydroxyphenyl)propanoate + NAD(+) + NH4(+) => H(+) + L-dopa + NADH


name: APC/C:Cdh1-mediated degradation of Skp2 (Dictyostelium discoideum)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Caenorhabditis elegans)


name: D-glucaro-1,4-lactone <=> 5-dehydro-4-deoxy-D-glucarate + H(+)


name: PLG(20-810) binds anti-fibrinolytics (Homo sapiens)


name: 3beta-hydroxy-5alpha-androstan-17-one + NADP(+) => 5alpha-androstan-3,17-dione + H(+) + NADPH


name: D-cellotriose + O2 <=> D-cellotriono-1,5-lactone + H2O2


name: dodecanoate + H(+) + holo-[ACP] => dodecanoyl-[ACP] + H2O


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Sus scrofa)


name: CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Drosophila melanogaster)


name: Basigin binds Matrix metalloproteinase-1 (Xenopus tropicalis)


name: chloride(out) + L-glutamine(out) + 2 Na(+)(out) => chloride(in) + L-glutamine(in) + 2 Na(+)(in)


name: H(+) + penilactone D => (S)-5-carboxymethyl-tetronate + o-quinone methide


name: (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H(+) + H2O => FMNH2 + N-acetyl-S-methyl-L-cysteine + O2


name: TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine (Homo sapiens)


name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Bos taurus)


name: 3-hydroxypent-4-ene nitrile + sulfate + sulfur => (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate


name: AMP + diphosphate + octanoyl-CoA => ATP + CoA + octanoate


name: FA core complex assembles at DNA interstrand crosslinks (ICLs) (Mus musculus)


name: SLC29A1 transports RBV from extracellular region to cytosol (Mus musculus)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] = 15alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 3'-hydro-2'-hydroxy-beta-oxodihydrochalcone + UDP-alpha-D-glucose <=> a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone + H(+) + UDP


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Bos taurus)


name: Phosphorylation of AXN and APC by SGG (Drosophila melanogaster)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Caenorhabditis elegans)


name: a quinone + L-quinate <=> 3-dehydroquinate + a quinol


name: Formation of the Cleavage and Polyadenylation Complex (Rattus norvegicus)


name: (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + H2O = (-)-geosmin


name: CHD1L is recruited to GG-NER site (Sus scrofa)


name: USP19 binds HIF1A,BIRC2,BIRC3 (Mus musculus)


name: (2E)-butenoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin] => butanoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Sus scrofa)


name: 1-hydroxy-2-naphthoate + O2 = (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H(+)


name: corticosterone + H(+) + NADPH => 5beta-dihydrocorticosterone + NADP(+)


name: (3Z)-phycoerythrobilin + oxidized 2[4Fe-4S]-[ferredoxin] => 15,16-dihydrobiliverdin + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: L-tyrosyl-[protein] + NAD(+) = H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein]


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Caenorhabditis elegans)


name: H(+)(out) + nitrite(in) => H(+)(in) + nitrite(out)


name: CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate => 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + O2


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: chanoclavine-I aldehyde + H(+) + NADH => chanoclavine-I + NAD(+)


name: DNMT3A binds Me2sR4-HIST1H4 (Mus musculus)


name: Sequestration of BAD protein by 14-3-3 (Rattus norvegicus)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Bos taurus)


name: Activated CIT binds KIF14 and PRC1 (Rattus norvegicus)


name: PARVA associates with Paxillin (Danio rerio)


name: Activated FGFR3 phosphorylates PLCG1 (Drosophila melanogaster)


name: indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP


name: Complement factor I binds to MCP, CR1:C4b, C3b (Gallus gallus)


name: a 2,3-saturated acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> a (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + octadecanoate


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol => 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA


name: PLK1 phosphorylates NUDC (Gallus gallus)


name: Insertion of correct bases opposite the lesion by POLH (Xenopus tropicalis)


name: PARN deadenylates mRNA (Canis familiaris)


name: H(+) + S-adenosyl-L-methionine <=> CO2 + S-adenosyl 3-(methylsulfanyl)propylamine


name: (2E)-octenoyl-CoA + H2O <=> (3R)-hydroxyoctanoyl-CoA


name: p-S215 FOXO3 translocates to the nucleus (Caenorhabditis elegans)


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Xenopus tropicalis)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Sus scrofa)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Sus scrofa)


name: SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Sus scrofa)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)


name: 3 H(+) + H2O + urea-1-carboxylate = 2 CO2 + 2 NH4(+)


name: CYP17A1 cleaves 17aHPROG to ANDST (Danio rerio)


name: alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + UDP-N-acetyl-alpha-D-glucosamine => alpha-D-Man-(1->3)-[alpha-D-GlcNAc-(1->2)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + H(+) + UDP


name: CYP11B2 oxidises 18HCORST to ALDO (Bos taurus)


name: ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Bos taurus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Caenorhabditis elegans)


name: 2-oxoglutarate + gibberellin A15 + O2 = CO2 + gibberellin A24 + H2O + succinate


name: SMPD4 hydrolyzes sphingomyelin (ER membrane) (Caenorhabditis elegans)


name: IL21 receptor JAK phosphorylation (Canis familiaris)


name: Phosphorylation and activation of eIF4B by activated S6K1 (Bos taurus)


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Sus scrofa)


name: RNLS:FAD oxidises dh-beta-NAD to NAD+ (Canis familiaris)


name: diphosphate + H(+)(in) + H2O => 2 H(+)(out) + 2 phosphate


name: propan-2-ol:coenzyme F420 oxidoreductase activity


name: botD LC cleaves target cell VAMP1 (Homo sapiens)


name: p-Y420-FYN is phosphorylated on S21 (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphate => a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: choline + H(+) + NADH + O2 <=> glycolaldehyde + H2O + NAD(+) + trimethylamine


name: 2-oxoglutarate + 4-(trimethylamino)butanoate + O2 <=> carnitine + CO2 + succinate


name: 4-O-(beta-D-glucosyl)-(E)-coniferol + A <=> 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + AH2


name: 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one (Xenopus tropicalis)


name: estrone 3-sulfate(out) + glutarate(in) => estrone 3-sulfate(in) + glutarate(out)


name: CoA + glutarate + H(+) => glutaryl-CoA + H2O


name: dehydrocholate + H(+) + NADPH => 7alpha-hydroxy-3,12-dioxo-5beta-cholanate + NADP(+)


name: histone H3K36 trimethyltransferase activity


name: Active ALK phosphorylates SHC1 (Bos taurus)


name: Release of p-STAT2:p-STAT1 dimer (Gallus gallus)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Mus musculus)


name: PIAS2-2 SUMOylates THRA with SUMO3 (Bos taurus)


name: 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: cholesterol + UDP-alpha-D-glucose = cholesteryl 3-beta-D-glucoside + H(+) + UDP


name: Activation of JNK by DSCAM (Canis familiaris)


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Canis familiaris)


name: Dephosphorylation of inactive SRC by PTPB1 (Gallus gallus)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Bos taurus)


name: Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA (Xenopus tropicalis)


name: mycinamicin III + S-adenosyl-L-methionine = H(+) + mycinamicin IV + S-adenosyl-L-homocysteine


name: Packaging of RdRP complex with replicated hRSV A nucleocapsid (Homo sapiens)


name: CA4:Zn2+ hydrates CO2 to HCO3- (Danio rerio)


name: ATP + N-acetyl-alpha-D-galactosamine <=> ADP + H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate


name: O2 + reduced [NADPH--hemoprotein reductase] + zeinoxanthin = H(+) + H2O + lutein + oxidized [NADPH--hemoprotein reductase]


name: oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Bos taurus)


name: dihydrosanguinarine + O2 + reduced [NADPH--hemoprotein reductase] = 10-hydroxydihydrosanguinarine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + NH4(+) => H(+) + 2 H2O + pyridinestrone carboxylate


name: H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + oxytetracycline = 5a,11a-dehydrooxytetracycline + reduced coenzyme F420-(gamma-L-Glu)(n)


name: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine


name: Lactoperoxidase (LPO) produces OSCN- (Dictyostelium discoideum)


name: H(+) + hercynine + S-adenosyl-L-homocysteine => N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-methionine


name: 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 4-ethylphenol


name: cyclohexanecarbaldehyde + hydrogen cyanide => (2S)-2-cyclohexyl-2-hydroxyacetonitrile


name: 2,3-dihydroxyindole + O2 => anthranilate + CO2 + H(+)


name: [protein]-disulfide + H(+) + NADPH => [protein]-dithiol + NADP(+)


name: 4-phosphooxy-L-aspartyl-tRNA(Asn) + NH4(+) => H(+) + L-asparaginyl-tRNA(Asn) + phosphate


name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Sus scrofa)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Rattus norvegicus)


name: 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one (Caenorhabditis elegans)


name: PIAS4 SUMOylates TOP2A with SUMO2,3 (Bos taurus)


name: GTP + L-histidyl-[RNA ligase] <=> diphosphate + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase]


name: DCXR tetramer reduces L-xylulose to xylitol (Canis familiaris)


name: (E)-caffeoyl-AMP + diphosphate => (E)-caffeate + ATP + H(+)


name: Expression of Proteasome activator complex subunit 2 (Homo sapiens)


name: Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane (Drosophila melanogaster)


name: cortisone + NAD(+) = 17alpha-hydroxypregn-4-en-3,11,20-trione-21-al + H(+) + NADH


name: USP24 deubiquitinates DDB2 (Gallus gallus)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein] => acetyl-CoA + N-terminal L-methionyl-L-lysyl-[protein]


name: The Interleukin 1 receptor complex binds Tollip (Canis familiaris)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Canis familiaris)


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O => 1-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: Assembly of the anterograde IFT train (Mus musculus)


name: S-methylmethionine transmembrane transporter activity


name: HSD17B11 dehydrogenates EST17b to E1 (Rattus norvegicus)


name: H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + n Na(+)(in) => CO2 + N(6)-biotinyl-L-lysyl-[protein] + n Na(+)(out)


name: (22S)-22-hydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase] = (22S)-22-hydroxycampest-4-en-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Dictyostelium discoideum)


name: SORD tetramer oxidizes xylitol to D-xylulose (Sus scrofa)


name: 2 L-ascorbate + N-tetradecanoylglycine + O2 <=> H2O + 2 monodehydro-L-ascorbate radical + N-tetradecanoyl-(2S)-hydroxyglycine


name: acetoacetate + butanoyl-CoA <=> acetoacetyl-CoA + butanoate


name: p-S216-CDC25C translocates to the cytosol (Schizosaccharomyces pombe)


name: (R,R)-chrysanthemol + NAD(+) => (1R,3R)-chrysanthemal + H(+) + NADH


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Sus scrofa)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Canis familiaris)


name: SLC29A1 transports RBV from extracellular region to cytosol (Bos taurus)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Gallus gallus)


name: L-tryptophan(in) + Na(+)(in) <=> L-tryptophan(out) + Na(+)(out)


name: ATP + beta-nicotinamide D-ribonucleotide + H(+) = diphosphate + NAD(+)


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Sus scrofa)


name: IL1R1:IL1:IL1RAP binds MYD88 homodimer (Homo sapiens)


name: JMJD6 demethylates MeR3-histone H3 (Bos taurus)


name: Peptide transfer from P-site tRNA to the A-site tRNA (Homo sapiens)


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Rattus norvegicus)


name: p130Cas and C3G bind PDGFR bound Crk (Sus scrofa)


name: (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+) => (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H(+) + NADPH


name: Phosphorylation of RAF1 mutants (Homo sapiens)


name: Beta-catenin recruits CDC73 and LEO1 (Caenorhabditis elegans)


name: NOTUM releases Hh-Np:GPC5 from the plasma membrane (Mus musculus)


name: PKA/PKG phosphorylate Rap1GAP2 (Caenorhabditis elegans)


name: (3R)-hydroxyeicosanoyl-CoA <=> (2E)-eicosenoyl-CoA + H2O


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Danio rerio)


name: 4 H(+) + 6 H2O + ophiobolin C + 4 oxidized [NADPH--hemoprotein reductase] => 4 O2 + ophiobolin F + 4 reduced [NADPH--hemoprotein reductase]


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Rattus norvegicus)


name: 3,4,5-trihydroxybenzoate + H(+) = 1,2,3-trihydroxybenzene + CO2


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: H(+)(out) + L-tryptophan(out) => H(+)(in) + L-tryptophan(in)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)


name: RAC2:GTP binds NOX2 complex (Gallus gallus)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 => (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O


name: SLC46A1 transports hemes from extracellular region to cytosol (Bos taurus)


name: an S-(2-hydroxyacyl)glutathione + H2O => a 2-hydroxy carboxylate + glutathione + H(+)


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Danio rerio)


name: Activation of Cdc42 by pVav1 (Bos taurus)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Caenorhabditis elegans)


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Rattus norvegicus)


name: NPM1-ALK translocates to the nucleus (Homo sapiens)


name: 3,6-dichloropyridine-2,5-diol + FADH2 + O2 <=> 6-chloro-3-hydroxypyridine-2,5-dione + chloride + FAD + 2 H(+) + H2O


name: H(+) + NADPH + uridine(17) in tRNA => 5,6-dihydrouridine(17) in tRNA + NADP(+)


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Bos taurus)


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Rattus norvegicus)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Rattus norvegicus)


name: NEIL1 cleaves FapyG from damaged DNA (Mus musculus)


name: Fe(3+)(out) + L-ascorbate(in) = Fe(2+)(out) + H(+) + monodehydro-L-ascorbate radical(in)


name: AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] <=> 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase]


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)


name: Assembly of IFT A complex (Mus musculus)


name: 2-succinylbenzoyl-CoA + AMP + diphosphate => 2-succinylbenzoate + ATP + CoA


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate


name: ST3GAL5 transfers NeuNAc to ceramides (Bos taurus)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Gallus gallus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Mus musculus)


name: (2S)-2-amino-2'-deoxyadenylo-succinate = dZMP + fumarate


name: glycyl-L-histidine + H2O <=> glycine + L-histidine


name: 2-oxoglutarate + L-hyoscyamine + O2 => (6S)-6-hydroxyhyoscyamine + CO2 + succinate


name: 1-acyl-2-(9Z,12Z,15Z-octadecatrienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 1-acyl-2-(9Z,12Z-octadecadienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Constitutive phosphorylation  by pERK1/2 (Canis familiaris)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(38-hydroxyoctatriacontenoyl)-sphing-4-enine = a diacylglycerol + an N-(38-(9Z,12Z-octadecadienoyloxy)-octatriacontenoyl)-sphing-4-enine


name: CO2 + UMP => H(+) + orotidine 5'-phosphate


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Caenorhabditis elegans)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Mus musculus)


name: H2O + UDP-alpha-D-glucuronate => 1-phospho-alpha-D-glucuronate + 2 H(+) + UMP


name: A + all-trans-3,4-didehydro-13,14-dihydroretinol <=> AH2 + all-trans-3,4-didehydroretinol


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-alkyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine + H(+)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Canis familiaris)


name: Syndecans 2, (4) bind TGFB1 (Caenorhabditis elegans)


name: CoA + salvianin => 4'''-demalonylsalvianin + malonyl-CoA


name: RAD52 promotes single strand annealing at resected DNA DSBs (Rattus norvegicus)


name: (S)-lactate + 2 Fe(III)-[cytochrome c] => 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: PLG(20-810) binds anti-fibrinolytics (Mus musculus)


name: PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Bos taurus)


name: snRNA 2'-O-ribose methylation guide activity


name: 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP => 16alpha,17beta-estriol + UDP-alpha-D-glucuronate


name: ceritinib-resistant ALK mutants don't bind ceritinib (Homo sapiens)


name: Activation of Potassium transport channels (Caenorhabditis elegans)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Drosophila melanogaster)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + L-glutamate + O2 <=> (3R)-3-hydroxy-L-glutamate + CO2 + succinate


name: (1R,2R,4R)-dihydrocarveol + NAD(+) <=> (1R,4R)-dihydrocarvone + H(+) + NADH


name: Activated FGFR2 binds FRS3 (Gallus gallus)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Gallus gallus)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O => (S)-2-amino-6-oxoheptanedioate


name: CYP3A4 monooxygenates ATV to 2-OH-ATV (Homo sapiens)


name: (2R)-3-phosphoglycerate + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+)


name: NEMO binds polyubiquitinated IRAK1 (Drosophila melanogaster)


name: Hh C-terminal fragments are degraded by the proteasome (Sus scrofa)


name: 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA => 1-octanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: H2O + L-homoseryl-tRNA(Lys) => H(+) + L-homoserine + tRNA(Lys)


name: N-hydroxy-L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-octanoyl-4'-phosphopantetheine => H2O + octanoyl-CoA


name: 4-methylpentanoyl-CoA + H2O => 4-methylpentanoate + CoA + H(+)


name: 4-hydroxy-all-trans-beta-carotene + AH2 + O2 = 4,4-dihydroxy-all-trans-beta-carotene + A + H2O


name: H2O + L-lysine + NADP(+) => (S)-2-amino-6-oxohexanoate + H(+) + NADPH + NH4(+)


name: 2-hydroxy-1-phenylethan-1-amine + H2O + NAD(+) <=> 2-hydroxyacetophenone + H(+) + NADH + NH4(+)


name: arabidiol <=> (S)-2,3-epoxysqualene + H2O


name: cyclopentanone + H(+) + NADPH + O2 = 5-valerolactone + H2O + NADP(+)


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Homo sapiens)


name: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Plasmodium falciparum)


name: PLC-gamma binds to the active receptor (Sus scrofa)


name: NTPDase8 hydrolyzes nucleoside diphosphates (Danio rerio)


name: guanosine 3'-diphosphate 5'-triphosphate + H2O = diphosphate + GTP + H(+)


name: 7-O-methylvitexin 2''-O-beta-L-rhamnoside + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside


name: GST dimers cleave AZA to 6MP (Mus musculus)


name: CUBN dissociates from 25(OH)D (Rattus norvegicus)


name: Histidine is decarboxylated to histamine (Drosophila melanogaster)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b (Caenorhabditis elegans)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine => 1-tetradecanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: p-T68-CHEK2 dimerizes (Rattus norvegicus)


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Mus musculus)


name: Phosphorylation of beta and gamma subunits by LYN (Bos taurus)


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Mus musculus)


name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Mus musculus)


name: RHOH binds GTP (Dictyostelium discoideum)


name: Recruitment of SYK to p-FCERI gamma subunit (Rattus norvegicus)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Saccharomyces cerevisiae)


name: (S)-malate + a quinone <=> a quinol + oxaloacetate


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Gallus gallus)


name: 2-amino-2-deoxy-D-gluconate(out) + N(pros)-phospho-L-histidyl-[protein] => 2-amino-2-deoxy-D-gluconate 6-phosphate(in) + L-histidyl-[protein]


name: ATP + thiamine => AMP + H(+) + thiamine diphosphate


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Sus scrofa)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Drosophila melanogaster)


name: 2-dehydro-3-deoxy-D-galactonate <=> D-glyceraldehyde + pyruvate


name: (S)-tetrahydrocolumbamine + H(+) + S-adenosyl-L-homocysteine => (S)-scoulerine + S-adenosyl-L-methionine


name: (R)-pantoate + beta-alanine => (R)-pantothenate + H2O


name: ATF4 and phospho-ATF2 bind the DDIT3 promoter (Homo sapiens)


name: Formation of caspase-1 p10/p20 dimer (Rattus norvegicus)


name: Recruitment of PI3K to plasma membrane (Gallus gallus)


name: (-)-5-epi-eremophilene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 4-(trifluoromethyl)benzyl alcohol + NAD(+) => 4-(trifluoromethyl)benzaldehyde + H(+) + NADH


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Mus musculus)


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Canis familiaris)


name: [(1->4)-alpha-D-galacturonosyl](n) => 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate + [(1->4)-alpha-D-galacturonosyl](n-2)


name: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)


name: (2E)-octenoyl-CoA + H(+) + NADH <=> NAD(+) + octanoyl-CoA


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Saccharomyces cerevisiae)


name: TDG glycosylase mediated recognition and binding of thymine opposite guanine (Gallus gallus)


name: Histone acetyltransferases are recruited to the TFF1 gene (Sus scrofa)


name: PRLR is phosphorylated at Ser-349 (Homo sapiens)


name: Association of  PARVA with TESK1 (Sus scrofa)


name: an acyl-CoA + sn-glycerol 3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + CoA


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 <=> (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate


name: CDK1 phosphorylates LBR (Rattus norvegicus)


name: DNA-directed 5'-3' RNA polymerase activity


name: acetyl-CoA + an N-hydroxyarylamine <=> an N-acetoxyarylamine + CoA


name: LC3 de-lipidation by ATG4 (Canis familiaris)


name: [(1->4)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate => [(1->4)-beta-D-mannosyl](n) + phosphate


name: Dissociation of cytosolic HSF1:HSP90 complex (Dictyostelium discoideum)


name: Insertion of correct bases opposite the lesion by POLH (Mus musculus)


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (3S,6E)-nerolidol + diphosphate


name: ATP + L-seryl-[tau protein] => ADP + H(+) + O-phospho-L-seryl-[tau protein]


name: (-)-5'-demethylyatein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (-)-bursehernin + O2 + reduced [NADPH--hemoprotein reductase]


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Drosophila melanogaster)


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-[(9Z)-octadecenoylamino]ethyl (9Z)-octadecenoate => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(9Z-octadecenoyl) ethanolamine


name: light-activated voltage-gated calcium channel activity


name: L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-methionine = 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-homocysteine


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate <=> alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Gallus gallus)


name: 3-hydroxy-6-carboxyhexanoyl-CoA + NAD(+) <=> 3-oxo-6-carboxyhexanoyl-CoA + H(+) + NADH


name: NKX3-2 binds RUNX2 gene promoter (Homo sapiens)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Bos taurus)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Mus musculus)


name: CALCR binds gepants (Caenorhabditis elegans)


name: a long-chain fatty acid + ATP + L-cysteinyl-[protein] => AMP + diphosphate + S-(long-chain fatty acyl)-L-cysteinyl-[protein]


name: H2O + L-cysteinyl-[sulfatase] + S-adenosyl-L-methionine = 3-oxo-L-alanyl-[sulfatase] + 5'-deoxyadenosine + 2 H(+) + hydrogen sulfide + L-methionine


name: "cysteine-type anaerobic sulfatase-maturating enzyme"


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Gallus gallus)


name: RNF8 and RNF168 ubiquitinate KDM4A,B (Bos taurus)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Mus musculus)


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Rattus norvegicus)


name: H(+) + N(2)-methylguanosine(2069) in 23S rRNA + S-adenosyl-L-homocysteine => guanosine(2069) in 23S rRNA + S-adenosyl-L-methionine


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Sus scrofa)


name: 2 S-adenosyl-L-methionine + squalene => 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: Proteasome mediated degradation of COP1 (Canis familiaris)


name: cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase] => apo-[corrinoid adenosyltransferase] + cob(II)yrinate a,c diamide


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Mus musculus)


name: TRAF3 binds TICAM1:activated TLR4 complex (Rattus norvegicus)


name: L-aspartate(in) + sulfate(out) => L-aspartate(out) + sulfate(in)


name: AH2 + NH4(+) + O2 <=> A + H(+) + H2O + hydroxylamine


name: a sphingoid base + hexadecanoyl-CoA => an N-hexadecanoyl-sphingoid base + CoA + H(+)


name: ciliary neurotrophic factor receptor binding


name: HBEGF-bound EGFR forms a heterodimer with GPNMB (Sus scrofa)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Homo sapiens)


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Gallus gallus)


name: H2O2 + sanguinarine => dihydrosanguinarine + H(+) + O2


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Schizosaccharomyces pombe)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene = 1,2,4-trichlorobenzene + chloride + H(+)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Gallus gallus)


name: Thrombin-activated PARs binds G-protein Gq (Mus musculus)


name: (R)-2-hydroxypropyl-coenzyme M = (R)-1,2-epoxypropane + coenzyme M


name: 1-carboxybiuret + NH4(+) => H2O + triuret


name: CDC42 and PIP2 bind WASL, activating it (Caenorhabditis elegans)


name: L-lysine + O2 <=> 5-aminopentanamide + CO2 + H2O


name: 2-methylbutanoyl-CoA + H2O => 2-methylbutanoate + CoA + H(+)


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Gallus gallus)


name: CASP4, CASP5 cleave GSDMD (Mus musculus)


name: EGFRvIII does not bind CBL (Homo sapiens)


name: dihydroprecondylocarpine acetate + NADP(+) => H(+) + NADPH + precondylocarpine acetate


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Sus scrofa)


name: p-S400-Cot phosphorylates NIK (Homo sapiens)


name: 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NAD(+) => 5alpha-cholest-8-en-3-one + CO2 + NADH


name: 4-thiouridine + ATP => 4-thiouridine 5'-phosphate + ADP + H(+)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Sus scrofa)


name: RAC1:GTP binds NOX3 complex (Bos taurus)


name: "23S rRNA pseudouridine(955/2504/2580) synthase"


name: HTRA2 binds NDUFA13 (GRIM-19) (Mus musculus)


name: H(+) + kanamycin B + UDP => neamine + UDP-alpha-D-kanosamine


name: CLCN7:OSTM1 exchanges Cl- for H+ (Caenorhabditis elegans)


name: a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + a 5'-end dephospho-ribonucleoside-RNA => a ribonucleotidyl-ribonucleotide-RNA + GMP + H(+)


name: 3',5-dihydroxy-3,4',7-trimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Sus scrofa)


name: L-valine(in) + Na(+)(in) = L-valine(out) + Na(+)(out)


name: Resynthesis of excised residue by POLB (Rattus norvegicus)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)


name: D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-GDP = GDP + glycolate + H(+)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 = 15-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate


name: RAN:GTP recruits nuclear envelope (NE) membranes (Sus scrofa)


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: CYTH proteins bind ARF1:GTP (Canis familiaris)


name: IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Canis familiaris)


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Rattus norvegicus)


name: histone H1R54 arginine deiminase activity


name: HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Saccharomyces cerevisiae)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Saccharomyces cerevisiae)


name: TCN2 binds RCbl in the circulation (Mus musculus)


name: THEM86B hydrolyses PMCHO, PMETAM (Xenopus tropicalis)


name: [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Bos taurus)


name: CD22 binds B-cell receptor (Mus musculus)


name: a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+) => a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Bos taurus)


name: PMM1,2 isomerise Man6P to Man1P (Xenopus tropicalis)


name: 3-hydroxybenzoate + ATP + CoA => 3-hydroxybenzoyl-CoA + AMP + diphosphate


name: (R)-carnitine + Co(I)-[quaternary-amine-specific corrinoid protein] + H(+) <=> (3R)-4-(dimethylamino)-3-hydroxybutanoate + methyl-Co(III)-[quaternary-amine-specific corrinoid protein]


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Mus musculus)


name: 3-methylbutanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 3 CO2 + 4 CoA + phlorisovalerophenone


name: H2O + pyridoxal 5'-phosphate <=> phosphate + pyridoxal


name: Pol II elongation complex moves on the template as transcript elongates (Caenorhabditis elegans)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Drosophila melanogaster)


name: glycine + hydrogen sulfide + NAD(+) = ADP-5-ethyl-4-methylthiazole-2-carboxylate + H(+) + 3 H2O + nicotinamide


name: "sulfide-dependent adenosine diphosphate thiazole synthase"


name: spermidine:feruloyl CoA N-acyltransferase activity


name: alpha,alpha-trehalose + phosphate => alpha-D-glucose + alpha-D-glucose 1-phosphate


name: Interaction of MyoD:E protein with MEF2 (Canis familiaris)


name: a 5'-end diphospho-ribonucleoside in mRNA + H(+) + phosphate => a 5'-end triphospho-ribonucleoside in mRNA + H2O


name: 6 (S)-methylmalonyl-CoA + 4-nitrobenzoyl-CoA + 12 H(+) + malonyl-CoA + 6 NADPH => 7 CO2 + 8 CoA + demethyldeoxyspectinabilin + 5 H2O + 6 NADP(+)


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Schizosaccharomyces pombe)


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Mus musculus)


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H2O + NAD(+) <=> 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + 2 H(+) + NADH


name: H2O + leukotriene C4 => glycine + leukotriene F4


name: SRPK1/2 phosphorylates nucleoprotein (Homo sapiens)


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Sus scrofa)


name: Caspase-8 activates BID by cleavage (Gallus gallus)


name: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH


name: (S)-nicotine + 2 Fe(III)-[cytochrome c] => 2 Fe(II)-[cytochrome c] + 2 H(+) + N-methylmyosmine


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Bos taurus)


name: D-galactosamine 6-phosphate + H2O <=> D-tagatopyranose 1-phosphate + NH4(+)


name: OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Sus scrofa)


name: 3-hydroxydodecanoyl-CoA + H2O => 3-hydroxydodecanoate + CoA + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphate + CMP + 2 H(+) => a CDP-1,2-diacyl-sn-glycerol + H2O


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Homo sapiens)


name: FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) (Homo sapiens)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Drosophila melanogaster)


name: ISGylation of E2 conjugating enzymes (Mus musculus)


name: TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 (Gallus gallus)


name: Formation of the Spliceosomal P complex and exon ligation (Danio rerio)


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)


name: SUMOylation of TOP2A with SUMO1 (Homo sapiens)


name: Parenchymal atROL translocates to HSCs (Canis familiaris)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer(d18:1(4E)) + H(+) + UDP


name: 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: Exocytosis of ficolin-rich granule lumen proteins (Dictyostelium discoideum)


name: 2-dehydro-3-deoxy-L-rhamnonate => (S)-lactaldehyde + pyruvate


name: sulfur-containing amino acid secondary active transmembrane transporter activity


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)


name: p-PKR dimer phosphorylates TP53 tetramer (Canis familiaris)


name: 2 Na(+)(out) + taurocholate(out) => 2 Na(+)(in) + taurocholate(in)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol <=> a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: asperaculane D + O2 + reduced [NADPH--hemoprotein reductase] <=> asperaculane E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: quercitrin + UDP-beta-L-rhamnose <=> H(+) + quercetin 3,7-bis-O-alpha-L-rhamnoside + UDP


name: ERO1B oxidizes P4HB (Xenopus tropicalis)


name: dodecanal + NADP(+) = (2E)-dodecenal + H(+) + NADPH


name: beta-L-galactose 1-phosphate + H2O = L-galactose + phosphate


name: H(+) + L-arabinose + NADPH => L-arabinitol + NADP(+)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacylglycerol = a 1-acyl-sn-glycero-3-phosphoethanolamine + a triacylglycerol


name: Collagen IX is cross-linked to the surface of collagen type II fibrils (Xenopus tropicalis)


name: factor IXa associates with cell membrane (Bos taurus)


name: a steroid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = an 11beta-hydroxysteroid + H2O + 2 oxidized [adrenodoxin]


name: all-trans-10'-apo-beta-carotenal + O2 <=> 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + beta-ionone


name: dodecanal + H2O + O2 = dodecanoate + H(+) + H2O2


name: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid (Xenopus tropicalis)


name: (R)-2-hydroxy-fatty acid dehydrogenase activity


name: a ubiquinone + caffeine + H2O => 1,3,7-trimethylurate + a ubiquinol


name: Digestion of diacylglycerols by extracellular PTL:colipase (Xenopus tropicalis)


name: Activated FGFR1 binds SHC1 (Gallus gallus)


name: P4HB mediates disulfide bond formation in Proinsulin (Canis familiaris)


name: H2O + O2 + serotonin => (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4(+)


name: THEM86B hydrolyses PMCHO, PMETAM (Sus scrofa)


name: Melanospin is stimulated by light (Canis familiaris)


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Sus scrofa)


name: menadiol + 2 O2 => 2 H(+) + menadione + 2 superoxide


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Dictyostelium discoideum)


name: 9,10-phenanthroquinone + H(+) + NADPH <=> NADP(+) + phenanthrene-9,10-diol


name: a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP => a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP-alpha-D-glucose


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Saccharomyces cerevisiae)


name: Lactoferrin scavenges iron ions (Rattus norvegicus)


name: a hexanoate ester + H2O = an aliphatic alcohol + H(+) + hexanoate


name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Danio rerio)


name: eicosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 2-hydroxyeicosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: O2 + 2 plastoquinol-9 => 2 H2O + 4 hnu + 2 plastoquinone-9


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Gallus gallus)


name: CL-LK binds carbohydrates on target cell surface (Mus musculus)


name: SFTPA/SFTPD binds TLR2:TLR1 (Canis familiaris)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Mus musculus)


name: 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA


name: acetone + H(+) + NADPH + O2 => H2O + methyl acetate + NADP(+)


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Bos taurus)


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: Activated FGFR4 phosphorylates SHC1 (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Dictyostelium discoideum)


name: TASP1 cleaves KMT2A (Drosophila melanogaster)


name: 2 a plastoquinone + 2 H2O + 4 hnu <=> 2 a plastoquinol + O2


name: H(+) + NADH + uridine(20b) in tRNA => 5,6-dihydrouridine(20b) in tRNA + NAD(+)


name: (2Z,6E)-farnesyl diphosphate => (6R,7S)-himachala-9,11-diene + diphosphate


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Rattus norvegicus)


name: RAC2 translocates to the phagocytic vesicle membrane (Sus scrofa)


name: a 7(1),7(1)-dihydroxybacteriochlorophyllide c = a bacteriochlorophyllide e + H2O


name: 2-methylbutanoyl-CoA + H2O <=> 2-methylbutanoate + CoA + H(+)


name: SGK phosphorylates CREB1 (Canis familiaris)


name: ZFPM proteins bind GATA proteins (Homo sapiens)


name: indole-3-acetate carboxyl methyltransferase activity


name: 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 = 7-chloroindole-3-pyruvate imine dimer + 2 H2O


name: tRNA pseudouridine(65) synthase activity


name: D-xylono-1,5-lactone + H(+) + NADH => D-xylose + NAD(+)


name: L-arginine(in) + L-phenylalanine(out) = L-arginine(out) + L-phenylalanine(in)


name: acetyl-CoA + 4 H(+) + 6 malonyl-CoA = 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + 6 CO2 + 7 CoA + H2O


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Bos taurus)


name: UGTs glucuronate APAP to APAP-GlcA (Canis familiaris)


name: β-blockers bind ADRB1,2,3 (Rattus norvegicus)


name: oleate transmembrane transporter activity


name: 3-sulfanylpropanoate + O2 <=> 3-sulfinopropanoate + H(+)


name: Recruitment of transition zone proteins (Mus musculus)


name: PP2A methylation by LCMT1 (Xenopus tropicalis)


name: Slo3 Potassium Transport (Rattus norvegicus)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Homo sapiens)


name: 5alpha-cholest-8,14-dien-3beta-ol + H(+) + NADPH <=> 5alpha-cholest-8-en-3beta-ol + NADP(+)


name: a menaquinone + H(+) + S-adenosyl-L-homocysteine => a 2-demethylmenaquinone + S-adenosyl-L-methionine


name: Relaxin receptor 2 binds relaxin 2 and INSL3 (Drosophila melanogaster)


name: 2 Fe(III)-[cytochrome b5] + NADH <=> 2 Fe(II)-[cytochrome b5] + H(+) + NAD(+)


name: H2O + N(1)-acetylspermidine + O2 <=> 3-acetamidopropanal + H2O2 + putrescine


name: SIRT6 deacetylates RBBP8 (Rattus norvegicus)


name: (S)-carnitine(in) + Na(+)(in) => (S)-carnitine(out) + Na(+)(out)


name: Parkin binds Ub:UBE2N:UBE2V1 (Dictyostelium discoideum)


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O => [DsrC protein]-disulfide + 3 AH2 + 2 H(+) + sulfite


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Canis familiaris)


name: (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] => 1-aci-nitro-2-(phenyl)ethane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Mus musculus)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Homo sapiens)


name: N-formyl-L-aspartate + NH4(+) => H2O + N-formimidoyl-L-aspartate


name: an inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose => an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + GDP + H(+)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Caenorhabditis elegans)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Plasmodium falciparum)


name: glycine + hexadecanoyl-CoA = CoA + H(+) + N-hexadecanoylglycine


name: E2F8 forms homodimers (Canis familiaris)


name: Activated FGFR3 phosphorylates PPTN11 (Gallus gallus)


name: 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 H(+) + 2 NADH + O2 <=> 2,5-dihydroxypyridine + H2O + 2 NAD(+) + succinate semialdehyde


name: PERP binds desmosomes (Caenorhabditis elegans)


name: Phosphorylation of STAT1 by JAK kinases (Bos taurus)


name: 1-hexadecanoylglycerone 3-phosphate + dodecan-1-ol => 1-O-dodecylglycerone 3-phosphate + H(+) + hexadecanoate


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Plasmodium falciparum)


name: 15,9'-di-cis-phytofluene + a plastoquinone => 9,9',15-tri-cis-zeta-carotene + a plastoquinol


name: Cis-heterodimerization of L1 and DM-GRASP/ALCAM/BEN (Homo sapiens)


name: CO2 + mugineate + succinate => 2'-deoxymugineate + 2-oxoglutarate + O2


name: 5,6,7,8-tetrahydromethanopterin + ATP + L-glutamate <=> 5,6,7,8-tetrahydrosarcinapterin + ADP + H(+) + phosphate


name: Plasma membrane resorption (Rattus norvegicus)


name: (1S,2S)-pseudoephedrine + NAD(+) = (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Homo sapiens)


name: (6E)-8-hydroxygeraniol + NADP(+) = (6E)-8-hydroxygeranial + H(+) + NADPH


name: anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Xenopus tropicalis)


name: acetochlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> ethyl formate + H2O + N-(2-ethyl-6-methylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Integrin alphaIIb beta3 activation (Drosophila melanogaster)


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Xenopus tropicalis)


name: H(+) + H2O + hydrazine => hydroxylamine + NH4(+)


name: decanoyl-CoA + glycine <=> CoA + H(+) + N-decanoylglycine


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Canis familiaris)


name: RAS GAPs bind RAS:GTP (Drosophila melanogaster)