name: [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl](n) + n CoA => [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Bos taurus)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Bos taurus)


name: JMJD6 demethylates Me2R3-histone H3 (Sus scrofa)


name: Active p38 MAPK phosphorylates MAPKAPK5 (Bos taurus)


name: S-methyl-1-thio-D-xylulose 5-phosphate => S-methyl-5-thio-D-ribulose 1-phosphate


name: PAK1 phosphorylates FLNA (Xenopus tropicalis)


name: H2O + juglone => naphthalene-1,2,4,8-tetrol


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Schizosaccharomyces pombe)


name: VAV2 is a GEF for Rho/Rac family kinases (Gallus gallus)


name: p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Bos taurus)


name: 3-oxo-(5Z-tetradecenoyl)-CoA + H(+) + NADH => (3S)-hydroxy-(5Z-tetradecenoyl)-CoA + NAD(+)


name: a 2'-O-methyluridine in 21S rRNA + H(+) + S-adenosyl-L-homocysteine => a uridine in 21S rRNA + S-adenosyl-L-methionine


name: ATP + beta-alanine + L-arginine => ADP + beta-alanyl-L-arginine + H(+) + phosphate


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Canis familiaris)


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Rattus norvegicus)


name: H(+) + L-arginyl-[protein] + lactate => H2O + N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein]


name: GRK2 binds CALM1:4Ca2+ (Caenorhabditis elegans)


name: Recruitment of IFNAR1 (Canis familiaris)


name: NKG2D homodimer interacting with ligands (Homo sapiens)


name: Phosphorylation of APC component of the destruction complex (Caenorhabditis elegans)


name: [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine


name: 1-phenyl-1,2-propanedione + H(+) + NADH => (S)-phenylacetylcarbinol + NAD(+)


name: (S)-5'-oxoaverantin + H(+) = (1'S,5'S)-averufin + H2O


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: a 1,2-saturated acyl-CoA + an acyl-CoA + H2O => an (R)-2-alkyl-3-oxoalkanoate + 2 CoA + H(+)


name: 3-(methylsulfanyl)propanoyl-CoA + butan-1-ol = butyl 3-(methylsulfanyl)propanoate + CoA


name: 2 2-oxoglutarate + a (3R)-3-[(carboxymethyl)amino]fatty acid + 2 O2 <=> a (3R)-3-isocyanyl-fatty acid + 3 CO2 + 2 H2O + 2 succinate


name: NTPDase4 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + tetradecanoyl-CoA => 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA


name: Intermediate 1 binds HP subcomplex to form Intermediate 2 (Caenorhabditis elegans)


name: a 3beta-hydroxysteroid ester + a diacylglycerol => a 3beta-hydroxysteroid + a triacylglycerol


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Canis familiaris)


name: 2 S-adenosyl-L-methionine + sphing-4-enine <=> 2 H(+) + N,N-dimethylsphing-4-enine + 2 S-adenosyl-L-homocysteine


name: 12-octadecanoyloxy-octadecanoate + H2O <=> 12-hydroxyoctadecanoate + H(+) + octadecanoate


name: bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE (Mus musculus)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Homo sapiens)


name: SLC19A2/3 transport extracellular THMN to cytosol (Sus scrofa)


name: The Kiss receptor GPR54 binds kisspeptin (Danio rerio)


name: Phosphorylated AP-1, Phospho JRA:Phospho KAY binds to a target gene and activates transcription (Drosophila melanogaster)


name: Dissociation of IRS-P from insulin receptor (Xenopus tropicalis)


name: dGMP + H2O = 2'-deoxyguanosine + phosphate


name: 4alpha-formylzymosterol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4alpha-carboxyzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: SARS-CoV-1 8b binds NLRP3 (Homo sapiens)


name: Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Bos taurus)


name: 2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine <=> 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate


name: Receptor CXCR6 binds CXCL16 ligand (Homo sapiens)


name: ADP + an [alpha-factor](out) + H(+) + phosphate => an [alpha-factor](in) + ATP + H2O


name: a dicarboxylate(in) + N-benzoylglycine(out) => a dicarboxylate(out) + N-benzoylglycine(in)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (-)-kolavenyl diphosphate


name: SESN1,2,3 bind overoxidized PRDX1 (Danio rerio)


name: SLC19A2/3 transport extracellular THMN to cytosol (Drosophila melanogaster)


name: AcK-NFE2L2-dependent SLC7A11 expression (Homo sapiens)


name: EHMT1:EHMT2 dimethylates TP53 (Drosophila melanogaster)


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Saccharomyces cerevisiae)


name: 2-oxo-3-sulfanylpropanoate + L-kynurenine <=> H2O + kynurenate + L-cysteine


name: TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains  (Canis familiaris)


name: SREBP1A,1C,2 translocates to the nucleus (Drosophila melanogaster)


name: ATP + H2O + L-glutamate(out) <=> ADP + H(+) + L-glutamate(in) + phosphate


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Sus scrofa)


name: Excess homocysteine yields homolanthionine and H2S (Saccharomyces cerevisiae)


name: 5-formimidoyltetrahydrofolate + L-glutamate <=> (6S)-5,6,7,8-tetrahydrofolate + N-formimidoyl-L-glutamate


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Mus musculus)


name: NADPH transfers electrons to FDXR (Plasmodium falciparum)


name: H2O + holo-[ACP] => (R)-4'-phosphopantetheine + apo-[ACP] + H(+)


name: dGTP + 2 H2O => dGMP + 2 H(+) + 2 phosphate


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Bos taurus)


name: 8-oxo-dADP + H2O <=> 8-oxo-dAMP + H(+) + phosphate


name: USP9X (FAM) deubiquitinates SMAD4 (Homo sapiens)


name: H2O + N-(9Z-octadecenoyl)-ethanolamine phosphate <=> N-(9Z-octadecenoyl) ethanolamine + phosphate


name: The Kiss receptor GPR54 binds kisspeptin (Mus musculus)


name: nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) (Homo sapiens)


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: PGH2 is reduced to PGF2a by AKR1C3 (Schizosaccharomyces pombe)


name: PIP3 recruits AKT to the membrane (Caenorhabditis elegans)


name: Autocatalytic activation of proMMP13 (Rattus norvegicus)


name: benzoyl-CoA + 2 H(+) + 3 malonyl-CoA = 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA


name: ATP + CoA + dinor-OPDA <=> AMP + dinor-OPDA-CoA + diphosphate


name: cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Canis familiaris)


name: ATP + biotin + CoA => AMP + biotinyl-CoA + diphosphate


name: MAP2K2 phosphorylates MAPK1 (Drosophila melanogaster)


name: RNASEs bind bacterial phospholipids (Mus musculus)


name: 2 H(+) + 2 NADH + 2 O2 + tetracenomycin A2 <=> H2O + 2 NAD(+) + tetracenomycin C


name: Src kinases phosphorylate VAV (Homo sapiens)


name: IL21 binds IL21R:JAK1 (Rattus norvegicus)


name: lecithin:11-cis retinol acyltransferase activity


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate


name: NSF ATPase activity dissociates cis-SNARE at the ER (Canis familiaris)


name: Degradation of multiubiquitinated Cyclin B (Xenopus tropicalis)


name: Association of DFF with alpha:beta importin (Canis familiaris)


name: Spontaneous hydrolysis of C3 thioester (Canis familiaris)


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)


name: CARD8 binds CASP9(1-416) (Canis familiaris)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Gallus gallus)


name: H2O + L-tryptophanamide => L-tryptophan + NH4(+)


name: NAD(+) + thromboxane B2 = 11-dehydro-thromboxane B2 + H(+) + NADH


name: L-arogenate + NAD(+) <=> CO2 + L-tyrosine + NADH


name: (9Z,12Z)-octadecadienoyl-CoA + AH2 + O2 = (9Z,12Z,15Z)-octadecatrienoyl-CoA + A + 2 H2O


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Schizosaccharomyces pombe)


name: 3 a quinone + protoporphyrinogen IX => 3 a quinol + protoporphyrin IX


name: 8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity


name: GDP + H(+) + phosphoenolpyruvate => GTP + pyruvate


name: A + all-trans-lycopene + dimethylallyl diphosphate + H2O = AH2 + diphosphate + nonaflavuxanthin


name: ligand-gated monoatomic cation channel activity


name: ADP + L-glutamine hydroxamate + phosphate => ATP + hydroxylamine + L-glutamate


name: a 5'-end (5'-phospho)-ribonucleoside-RNA + 2 S-adenosyl-L-methionine = a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + 2 S-adenosyl-L-homocysteine


name: SALMs1-3 bind each other in cis interactions (Canis familiaris)


name: PIAS1 SUMOylates THRB with SUMO1. (Homo sapiens)


name: TCN2 binds RCbl in the circulation (Xenopus tropicalis)


name: a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E)) + H(+) + UDP => a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP-alpha-D-galactose


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Dictyostelium discoideum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+) => 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-choline


name: PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Schizosaccharomyces pombe)


name: Activated FGFR4 phosphorylates SHC1 (Canis familiaris)


name: GSK3B phosphorylates p-NFE2L2 (Caenorhabditis elegans)


name: glycyl-L-leucine(out) + 2 H(+)(out) => glycyl-L-leucine + 2 H(+)(in)


name: type 6 metabotropic glutamate receptor binding


name: (2E,6E)-farnesyl diphosphate => (-)-vetispiradiene + diphosphate


name: 2 2-oxoglutarate + gibberellin A12 + H(+) + 3 O2 <=> 3 CO2 + gibberellin A9 + 2 H2O + 2 succinate


name: P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration


name: carboxyspermidine + H2O + NADP(+) <=> H(+) + L-aspartate 4-semialdehyde + NADPH + putrescine


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Mus musculus)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Canis familiaris)


name: Caspase-8 activates BID by cleavage (Rattus norvegicus)


name: 3,4-dihydroxybenzoate + ATP + holo-[aryl-carrier protein] = 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate


name: Carbonic anhydrase dehydrates bicarbonate (plasma membrane) (Rattus norvegicus)


name: PXLP-K56-SRR dimer deaminates D-Ser (Homo sapiens)


name: CYP3A43 6b-hydroxylates TEST (Xenopus tropicalis)


name: a propanoate ester + H2O <=> an aliphatic alcohol + H(+) + propanoate


name: 6beta-hydroxyestradiol-17beta + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase]


name: a 5'-end diphospho-adenosine in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein] = a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + L-lysyl-[protein]


name: 1-deoxy-D-xylulose + ATP => 1-deoxy-D-xylulose 5-phosphate + ADP + H(+)


name: mercaptopurine + S-adenosyl-L-methionine = 6-methylthiopurine + H(+) + S-adenosyl-L-homocysteine


name: Endonucleolytic RISC hydrolyzes target RNAs (Xenopus tropicalis)


name: G-protein subunits dissociate from WNT:FZD complex (Bos taurus)


name: EPH receptors autophosphorylate (Gallus gallus)


name: PCho is dephosphorylated to Cho by PHOSPHO1 (Drosophila melanogaster)


name: a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol(in) <=> a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol(out)


name: GP1b-IX-V binds 14-3-3-zeta (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 9R-hydroperoxy(5Z,7E,11Z,14Z)-eicosatetraenoate


name: H(+) + hexadecanoate + NADPH + O2 <=> 15-hydroxyhexadecanoate + H2O + NADP(+)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z,12Z)-octadecadienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: (E)-coniferyl acetate + CoA => (E)-coniferol + acetyl-CoA


name: GAR + 10-Formyl-THF => FGAR + THF (Danio rerio)


name: 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine => 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine


name: ATP + D-mannose <=> ADP + D-mannose 6-phosphate + H(+)


name: 5-dehydro-D-gluconate + H(+) + NADH => L-idonate + NAD(+)


name: L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-methyl-5'-thioadenosine


name: PP5 dephosphorylates RAF1 S338 (Xenopus tropicalis)


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Canis familiaris)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Gallus gallus)


name: ITGA4:ITGB1 binds natalizumab (Drosophila melanogaster)


name: all-trans-retinal + H2O + NAD(+) => all-trans-retinoate + 2 H(+) + NADH


name: cAMP induces dissociation of inactive PKA tetramers (Rattus norvegicus)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Bos taurus)


name: 2-oxoglutarate + 3-hydroxy-L-phenylalanine <=> 3-(3-hydroxyphenyl)pyruvate + L-glutamate


name: HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)


name: a neolactoside IV(3)-alpha-NeuNAc,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+) => a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + GDP-beta-L-fucose


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Sus scrofa)


name: 5 H(+)(in) + NADH + ubiquinone-8 = 4 H(+)(out) + NAD(+) + ubiquinol-8


name: 10-deoxymethynolide + dTDP-alpha-D-desosamine <=> 10-deoxymethymycin + dTDP + H(+)


name: (3R)-hydroxydecanoyl-[ACP] <=> (2E)-decenoyl-[ACP] + H2O


name: REV1 inserts dCMP opposite to AP sites in DNA (Danio rerio)


name: Formation of pre-mRNPs (Saccharomyces cerevisiae)


name: CYP3A4 can N-demethylate loperamide (Bos taurus)


name: SUMOylation of NR1H4 with SUMO1 (Mus musculus)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Bos taurus)


name: a thymine-cytidine dinucleotide in DNA => a thymidine(6-4)cytidine in DNA


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Drosophila melanogaster)


name: a butanoate ester + H2O => an aliphatic alcohol + butanoate + H(+)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with Tenascin (Bos taurus)


name: H2O + N-retinylidene-N-retinylphosphatidylethanolamine => a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-retinylidene-N-retinylethanolamine


name: H2O + L-glutamate 5-semialdehyde + NADP(+) => 2 H(+) + L-glutamate + NADPH


name: all-trans-4-oxoretinoate + UDP-alpha-D-glucuronate = all-trans-4-oxoretinoate 1-O-(beta-D-glucuronate) + UDP


name: ent-copalyl diphosphate => diphosphate + ent-atiserene


name: oxaloacetate(in) + sulfate(out) = oxaloacetate(out) + sulfate(in)


name: Phosphorylation of STAT1 by JAK kinases (Gallus gallus)


name: alpha-D-glucosamine 6-phosphate + H2O => beta-D-fructose 6-phosphate + NH4(+)


name: H2O + phenylacetyl-CoA <=> 2-phenylacetate + CoA + H(+)


name: p62:MEKK3 binds to TRAF6 (Canis familiaris)


name: (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase] <=> (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Plasmodium falciparum)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Caenorhabditis elegans)


name: Collagen type XIII ectodomain shedding (Canis familiaris)


name: a 1,2-diacyl-sn-glycerol + ATP <=> a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)


name: L-phenylalanine(in) + Na(+)(in) <=> L-phenylalanine(out) + Na(+)(out)


name: Caspase-mediated cleavage of Tau (Gallus gallus)


name: tBID binds to inactive BAX protein (Rattus norvegicus)


name: Hydrolysis of internal thioester in C4b (Xenopus tropicalis)


name: KLK5 cleaves and activates KLK8 (Mus musculus)


name: 1-O-alkyl-sn-glycero-3-phosphate + an acyl-CoA <=> 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + CoA


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Sus scrofa)


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Homo sapiens)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Mus musculus)


name: BRCA1-A complex deubiquitinates K63polyUb-histone H2A (Sus scrofa)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Mus musculus)


name: Aquaporins passively transport urea into cells (Bos taurus)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Xenopus tropicalis)


name: dihydrobunolol + NADP(+) <=> bunolol + H(+) + NADPH


name: 5-HT2 receptor can bind serotonin (Sus scrofa)


name: CGA and CGB3 bind to form Human chorionic gonadotropin (hCG) (Sus scrofa)


name: PIP3 recruits PDK1 and AKT to the membrane (Rattus norvegicus)


name: D-cycloserine(in) + H(+)(in) = D-cycloserine(out) + H(+)(out)


name: Monoubiquitinated PTEN translocates to the nucleus (Mus musculus)


name: [thioredoxin]-disulfide + prostamide F2alpha <=> [thioredoxin]-dithiol + prostamide H2


name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol (Saccharomyces cerevisiae)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Xenopus tropicalis)


name: Enzyme-bound ATP is released (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate = beta-copaene + diphosphate


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Schizosaccharomyces pombe)


name: TP53 binds the CASP6 gene (Homo sapiens)


name: RPE dimers isomerise RU5P to XY5P (Rattus norvegicus)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Rattus norvegicus)


name: H2O + wogonin 7-O-beta-D-glucuronate <=> D-glucuronate + H(+) + wogonin


name: prunetin + UDP-alpha-D-glucuronate <=> prunetin-4'-O-beta-D-glucuronide + UDP


name: alpha-D-mannose 1-phosphate + GMP + 2 H(+) => GDP-alpha-D-mannose + H2O


name: N(6)-(1,2-dicarboxyethyl)-AMP <=> AMP + fumarate


name: Translesion synthesis across unhooked ICL by POLN (Homo sapiens)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Drosophila melanogaster)


name: PANK4 hydrolyzes PPANT to pantetheine (Caenorhabditis elegans)


name: 2-oxoglutarate + fumigatonoid C + O2 = CO2 + H2O + novofumigatonin + succinate


name: 2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine => 2-heptyl-1-methoxy-4(1H)-quinolinone + H(+) + S-adenosyl-L-homocysteine


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+) + octadecanoate


name: EPHB:NMDAR binds TIAM1 (Caenorhabditis elegans)


name: trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Canis familiaris)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 <=> (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: p-CBL:GRB2 binds p-FRS2:activated FGFR3 (Homo sapiens)


name: 22-oxodocosanoate + H(+) + NADH => 22-hydroxydocosanoate + NAD(+)


name: Auto-ubiquitination of TRAF6 (Homo sapiens)


name: YKI binds to EX (Drosophila melanogaster)


name: TXLNA (IL14) binds syntaxin4 (Mus musculus)


name: a 3',5'-unsubstituted flavanone + O2 + reduced [NADPH--hemoprotein reductase] => a 3'-hydroxy,5'-unsubstituted flavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Gallus gallus)


name: glycyl-L-glutamate + H2O = glycine + L-glutamate


name: Autoglucosylation of GYG2 complexed with GYS2-b (Homo sapiens)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Sus scrofa)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Homo sapiens)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Homo sapiens)


name: Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Gallus gallus)


name: USP34 deubiquitinates AXIN1,AXIN2 (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 => N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-glycine


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Rattus norvegicus)


name: transforming growth factor beta receptor activity, type I


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Saccharomyces cerevisiae)


name: Ghrelin O-acyltransferase octanoylates Proghrelin (Bos taurus)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)


name: GNLY is transferred to the phagosome (Sus scrofa)


name: Activation of Calcineurin (Mus musculus)


name: (20S)-protopanaxadiol + O2 + reduced [NADPH--hemoprotein reductase] => (20S)-protopanaxatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Schizosaccharomyces pombe)


name: GPLD1 hydrolyses GPI-anchors from proteins (Rattus norvegicus)


name: p-SHC1 binds integrin alpha5beta1:fibronectin (Rattus norvegicus)


name: (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + chloride + FADH2 + O2 => (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: (R)-carnitine + NAD(+) <=> 3-dehydrocarnitine + H(+) + NADH


name: asparagusate + H(+) + NADH => 3-sulfanyl-2-(sulfanylmethyl)propanoate + NAD(+)


name: MLCL is acylated to CL by HADH (IM) (Bos taurus)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl-[protein] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl-[protein] + succinate


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + ATP <=> 3-diphospho-1D-myo-inositol 1,2,4,5-tetrakisphosphate + ADP


name: Factor B binds to C3(H2O) (Homo sapiens)


name: RGS proteins bind GNB5 and CCT/TRiC (Gallus gallus)


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Homo sapiens)


name: Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein (Homo sapiens)


name: uronic acid transmembrane transporter activity


name: E2F6 forms the PRC1L4 complex (Mus musculus)


name: Fibrillins bind BMPs (Rattus norvegicus)


name: GRB2:GAB1 binds to phosphorylated EGFR (Canis familiaris)


name: HES1 gene expression is stimulated by NOTCH4 (Homo sapiens)


name: 6-phosphoglucan, water dikinase activity


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Canis familiaris)


name: benzene-1,2,4-triol + O2 => 3-hydroxy-cis,cis-muconate + 2 H(+)


name: Caspase mediated cleavage of vimentin at IDVD (259) (Gallus gallus)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Mus musculus)


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> a 1-O-alkyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: 15-cis-phytoene + 2 diphosphate => 2 (2E,6E,10E)-geranylgeranyl diphosphate


name: Arresten binds integrin alpha1beta1 (Rattus norvegicus)


name: H2O + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] = ADP-D-ribose + L-lysyl-[protein]


name: citrate(out) + H(+)(out) => citrate(in) + H(+)(in)


name: PXLP-K56-SRR dimer deaminates L-Ser (Canis familiaris)


name: FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 (Homo sapiens)


name: H(+)(out) + L-histidine(out) => H(+)(in) + L-histidine(in)


name: 1,2,3-tri-(9Z,12Z,15Z)-octadecatrienoylglycerol + H2O <=> (9Z,12Z,15Z)-octadecatrienoate + 2,3-di-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycerol + H(+)


name: D-mannitol(out) + N(pros)-phospho-L-histidyl-[protein] => D-mannitol 1-phosphate(in) + L-histidyl-[protein]


name: a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine => H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide


name: structural constituent of skin epidermis


name: Bile salts bind FABP6 (Drosophila melanogaster)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: MeSec is hydrolysed to MeSeH by PXLP-K212-CTH (Homo sapiens)


name: ATP + thiamine diphosphate <=> ADP + thiamine triphosphate


name: carbamoyl phosphate + putrescine = H(+) + N-carbamoylputrescine + phosphate


name: acetyl-CoA + 10 H(+) + holo-[polyketide synthase] + 5 malonyl-CoA + 5 NADPH <=> 5 CO2 + 6 CoA + dodecapentaneoyl-[polyketide synthase] + 5 H2O + 5 NADP(+)


name: CAD hexamer transforms L-Gln to CAP (Bos taurus)


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Gallus gallus)


name: MET bound PI3K generates PIP3 (Xenopus tropicalis)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Caenorhabditis elegans)


name: PLOD3 binds Lysyl hydroxylated collagen propeptides (Mus musculus)


name: Basigin binds CD98 complex (Homo sapiens)


name: SLP-76 stimulates PLC gamma 2 (Rattus norvegicus)


name: E2F6:TFDP1:EPC1 binds the PRC2 complex (Rattus norvegicus)


name: carbohydrate-importing ABC transporter activity


name: ATP + H2O + sphing-4-enine 1-phosphate(in) => ADP + H(+) + phosphate + sphing-4-enine 1-phosphate(out)


name: D-ribose 5-phosphate + guanine => GMP + H2O


name: (9Z)-octadecenoate + H2O => 10-hydroxyoctadecanoate


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Sus scrofa)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Homo sapiens)


name: H(+) + NADH + O2 + salicylate = 2,5-dihydroxybenzoate + H2O + NAD(+)


name: (S)-indan-1-ol + NADP(+) <=> H(+) + indan-1-one + NADPH


name: H2O + indole-3-acetamide => (indol-3-yl)acetate + NH4(+)


name: steviol + UDP-alpha-D-glucose => H(+) + steviolmonoside + UDP


name: butan-2-one + H(+) + NADH + O2 => 1-hydroxy-2-butanone + H2O + NAD(+)


name: menaquinol-8 + nitrate => H2O + menaquinone-8 + nitrite


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Gallus gallus)


name: a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP(+) = an (R)-2-alkyl-3-oxoalkanoate + H(+) + NADPH


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Caenorhabditis elegans)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Xenopus tropicalis)


name: 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + O2 = a 2'-deoxyadenosine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: 2-oxoglutarate + a 1,N(2)-etheno-2'-deoxyguanosine in double-stranded DNA + H2O + O2 => a 2'-deoxyguanosine in double-stranded DNA + CO2 + glyoxal + succinate


name: Activated FGFR2 phosphorylates SHC1 (Canis familiaris)


name: Expression of ID2 and ID4 is repressed by EGR2:NAB (Homo sapiens)


name: (2S,4R)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine <=> (2R)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: (2E)-geranyl diphosphate + H2O => (S)-alpha-terpineol + diphosphate


name: ITPA hydrolyses ITP to IMP (Plasmodium falciparum)


name: 2-hydroxyethane-1-sulfonate = acetaldehyde + H(+) + sulfite


name: L-serine + NAD(+) = aminoacetaldehyde + CO2 + NADH


name: 1D-3-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine => myo-inositol + S-adenosyl-L-methionine


name: 3',5'-cyclic GMP(in) + ATP + H2O => 3',5'-cyclic GMP(out) + ADP + H(+) + phosphate


name: 4-(trifluoromethyl)benzaldehyde + H(+) + NADH => 4-(trifluoromethyl)benzyl alcohol + NAD(+)


name: acetaldehyde + H(+) + NADH + NH4(+) => ethylamine + H2O + NAD(+)


name: citrate(out) + tartrate(in) <=> citrate(in) + tartrate(out)


name: USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Bos taurus)


name: RRAGA,B exchanges GDP for GTP (Mus musculus)


name: DNA polymerase alpha:primase binds at the origin (Plasmodium falciparum)


name: H2O + NAD(+) + nonanal = 2 H(+) + NADH + nonanoate


name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) (Sus scrofa)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + (E)-4-coumaroyl-CoA = (E)-4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Drosophila melanogaster)


name: PTK2 autophosphorylates (Xenopus tropicalis)


name: CX3 complex formation (Xenopus tropicalis)


name: Activated TP receptor binds G-proten Gq (Bos taurus)


name: Corticosteroids bind to CBG in blood (Rattus norvegicus)


name: FAHD1:Zn2+ dimer hydrolyses OA to PYR (Canis familiaris)


name: ATP + CoA + salicylate = 2-hydroxybenzoyl-CoA + AMP + diphosphate


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Xenopus tropicalis)


name: 2-oxoglutarate + gibberellin A19 + O2 = CO2 + gibberellin A17 + H(+) + succinate


name: AURKB phosphorylates TP53 (Homo sapiens)


name: SREBP1A,1C,2:SCAP translocates to the Golgi (Homo sapiens)


name: Caspase 3-mediated cleavage of DFF45 (117) (Danio rerio)


name: LRP1 (CD91) binds Hemopexin:heme (Bos taurus)


name: Pink1 recruits Parkin to the outer mitochondrial membrane. (Danio rerio)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Canis familiaris)


name: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol (Bos taurus)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphate => 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate


name: ATP + hexadecanoate + holo-[(hydroxy)phthioceranic acid synthase] => AMP + diphosphate + hexadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: "diadenosine hexaphosphate hydrolase (ATP-forming)"


name: MLCL is acylated to CL by LCLAT1 (ER) (Saccharomyces cerevisiae)


name: MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Caenorhabditis elegans)


name: O2 + parthenolide + reduced [NADPH--hemoprotein reductase] <=> 3beta-hydroxyparthenolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: OTULIN,USP5 cleaves UBB yielding ubiquitin (Homo sapiens)


name: 1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + octanoate


name: 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO => O2 + quercetin


name: 3,5,7-trioxododecanoyl-CoA <=> CO2 + CoA + olivetol


name: 2-aryl-2-methylmalonate + H(+) <=> 2-arylpropionate + CO2


name: S-Farn-Me KRAS4B binds calmodulin (Sus scrofa)


name: a dolichyl D-xylosyl phosphate + UDP => a dolichyl phosphate + UDP-alpha-D-xylose


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Gallus gallus)


name: 2xTRAP hydrolyzes FMN to RIB (Homo sapiens)


name: Exogenous soluble antigen targeted to more stable early endosome (Sus scrofa)


name: beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol => cholesteryl 3-beta-D-glucoside + N-(9Z-octadecenoyl)-sphing-4-enine


name: Deacetylation of cleaved cohesin (Gallus gallus)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Gallus gallus)


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Bos taurus)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Xenopus tropicalis)


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Caenorhabditis elegans)


name: ADP + an N-acylsphing-4-enine(out) + H(+) + phosphate => an N-acylsphing-4-enine(in) + ATP + H2O


name: ORC6 binds KPNA1 or KPNA6 (Gallus gallus)


name: miR-106 microRNAs bind PTEN mRNA (Homo sapiens)


name: D-serine(in) + L-glutamine(out) + Na(+)(out) => D-serine(out) + L-glutamine(in) + Na(+)(in)


name: guanosine(46) in tRNA + S-adenosyl-L-methionine <=> N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine


name: diphosphate + thiamine phosphate => 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+)


name: SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Canis familiaris)


name: atROL binds RBP1 (Drosophila melanogaster)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine <=> di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine


name: 2-oxoglutarate + 3(1)-hydroxy-L-isoleucine + O2 <=> (4S)-3(1),4-dihydroxy-L-isoleucine + CO2 + succinate


name: Dissociation of p-Y427-SHC1 from insulin receptor (Sus scrofa)


name: 3-ADP-glycerate + phosphate => 3-ADP-2-phosphoglycerate + H2O


name: 4 O2 + ophiobolin F + 4 reduced [NADPH--hemoprotein reductase] = 4 H(+) + 6 H2O + ophiobolin C + 4 oxidized [NADPH--hemoprotein reductase]


name: an alkylamine + L-glutaminyl-[protein] => N(5)-alkyl-L-glutaminyl-[protein] + NH4(+)


name: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = 2-methoxy-6-(all-trans-octaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: Activation of voltage gated Potassium channels (Mus musculus)


name: an L-N-hydroxypolyhomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = an L-N,N-dihydroxypolyhomomethionine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: docosanoyl-CoA + glycine => CoA + H(+) + N-docosanoylglycine


name: coenzyme M + methyl-Co(III)-[trimethylamine-specific corrinoid protein] => Co(I)-[trimethylamine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: all-trans-retinol + O2 + reduced [NADPH--hemoprotein reductase] => all-trans-retinal + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Src kinases phosphorylate VAV (Bos taurus)


name: H2O + NADP(+) + nitrosobenzene = H(+) + NADPH + nitrobenzene


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Danio rerio)


name: A + testosterone => AH2 + androst-4-ene-3,17-dione


name: (2E,6E)-farnesyl diphosphate + H2O = 10-epi-juneol + diphosphate


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Gallus gallus)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Canis familiaris)


name: MECP2 binds the SIN3A co-repressor complex (Mus musculus)


name: citrate(out) + succinate(in) <=> citrate(in) + succinate(out)


name: acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O (Caenorhabditis elegans)


name: 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycerol 3-phosphate


name: "arabinogalactan exo alpha-(1,3)-alpha-D-galactosyl-(1->3)-L-arabinofuranosidase (non-reducing end)"


name: Formation of anchoring fibrils (Sus scrofa)


name: a 5'-end triphospho-ribonucleoside in mRNA + H2O <=> a 5'-end diphospho-ribonucleoside in mRNA + H(+) + phosphate


name: CBL binds TGFBR2 (Drosophila melanogaster)


name: POLI incorporates dNMP opposite to damaged DNA base (Mus musculus)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Homo sapiens)


name: dehypoxanthine futalosine + S-adenosyl-L-methionine = 5'-deoxyadenosine + cyclic dehypoxanthinylfutalosinate + H(+) + L-methionine


name: "cyclic dehypoxanthinyl futalosine synthase"


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Sus scrofa)


name: BCMO1:Fe2+ cleaves betaC to atRAL (Drosophila melanogaster)


name: 1-hexadecanoyl-sn-glycerol + phosphate => 1-hexadecanoyl-sn-glycero-3-phosphate + H2O


name: ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus (Homo sapiens)


name: (E)-sinapate + choline + H(+) => H2O + O-sinapoylcholine


name: D-glyceraldehyde + pyruvate => 2-dehydro-3-deoxy-D-gluconate


name: ADP + H(+) + O-phospho-L-threonyl-[protein] => ATP + L-threonyl-[protein]


name: SUMOylation of TFAP2A with SUMO1 (Homo sapiens)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Caenorhabditis elegans)


name: Association of procollagen type XX (Mus musculus)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Saccharomyces cerevisiae)


name: p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 (Mus musculus)


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Dictyostelium discoideum)


name: ERBB4 ubiquitination by WWP1/ITCH (Sus scrofa)


name: UGT1A10 transfers GlcA from UDP-GlcA to GCTN (Mus musculus)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Gallus gallus)


name: (R)-carnitine + decanoyl-CoA <=> CoA + O-decanoyl-(R)-carnitine


name: Estrogen-responsive CTSD expression (Homo sapiens)


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Homo sapiens)


name: glyoxylate + N(omega),N(omega)-dimethyl-L-arginine <=> 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> (+)-exo-beta-bergamotene + diphosphate


name: REV1 inserts dCMP opposite to AP sites in DNA (Drosophila melanogaster)


name: H(+) + NADPH + O2 + theophylline <=> 3-methylxanthine + formaldehyde + H2O + NADP(+)


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O => 2-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: DOLK phosphorylates DCHOL to DOLP (Gallus gallus)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Plasmodium falciparum)


name: P4 bind PGR (in the HSP90 chaperone complex) (Bos taurus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N(omega)-hydroxy-N(delta)-methyl-L-arginine = 2 Fe(III)-[cytochrome b5] + H2O + N(delta)-methyl-L-arginine


name: p-Y694-STAT5A, p-STAT5B dimerizes (Sus scrofa)


name: G6B binds PTPN6,PTPN11 (Rattus norvegicus)


name: Nucleoprotein translocates to the ERGIC outer membrane (Homo sapiens)


name: PGM1:Mg2+ isomerises G1P to G6P (Homo sapiens)


name: CRY is activated by light and binds to cytosolic TIM (Drosophila melanogaster)


name: Trafficking of GluR2-containing AMPA receptors to synapse (Drosophila melanogaster)


name: Thrombin proteolyzes IGF:IGFBP3:ALS (Rattus norvegicus)


name: H(+) + NADH + O2 + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)


name: acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-hydroxy-3-methylglutaryl-CoA + CoA + H(+)


name: RNF8 and RNF168 ubiquitinate H2AFX (Mus musculus)


name: hexadecanoyl-CoA + sphinga-(4E,8Z)-dienine => CoA + H(+) + N-hexadecanoylsphinga-(4E,8Z)-dienine


name: Proteinase-activated receptors can bind thrombin (Homo sapiens)


name: a CMP-N-acyl-beta-neuraminate + diphosphate => an N-acylneuraminate + CTP


name: Na(+)(out) + nicotinate(out) => Na(+)(in) + nicotinate(in)


name: CDK5:p25 phosphorylates FOXO3 (Homo sapiens)


name: 3,4-dihydroxybenzoate + CO2 + NADH => (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Gallus gallus)


name: (2R)-3-sulfolactate = H(+) + pyruvate + sulfite


name: Defective HEXB does not cleave the terminal GalNAc from DS (Homo sapiens)


name: Transcriptional activation of FAS monomer gene by ChREBP:MLX (Mus musculus)


name: monoglucosyl-enterobactin + UDP-alpha-D-glucose = diglucosyl-enterobactin + H(+) + UDP


name: D-ribulose 5-phosphate => D-arabinose 5-phosphate


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: Binding of ADAR2 homodimer to dsRNA duplex (Sus scrofa)


name: BRD7 binds TP53 and EP300 (Drosophila melanogaster)


name: Dimerized phospho-IRF3 migrates to the nucleus (Rattus norvegicus)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Xenopus tropicalis)


name: H2O + N-(11Z-eicosenoyl)-sphing-4-enine <=> (11Z)-eicosenoate + sphing-4-enine


name: L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu)


name: Release of Cytochrome c from mitochondria (Rattus norvegicus)


name: 2 H(+) + hexanoate + NADPH => H2O + hexanal + NADP(+)


name: a neolactoside nLc4Cer + CMP-N-acetyl-beta-neuraminate => a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + CMP + H(+)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Caenorhabditis elegans)


name: Dissociation of CaM and CAMK2 autophosphorylation (Plasmodium falciparum)


name: Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Bos taurus)


name: 1-dodecanoylglycerol + H2O => dodecanoate + glycerol + H(+)


name: ATP-dependent diacylglycerol kinase activity


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Xenopus tropicalis)


name: TGFBR2 phosphorylates TGFBR1 (Sus scrofa)


name: (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O <=> (13R)-S-cysteinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glycine


name: H(+) + O-phospho-L-serine + sulfite => L-cysteate + phosphate


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Danio rerio)


name: Formation of ADAR1 homodimer (Gallus gallus)


name: LDH tetramer oxidises LACT to PYR (Xenopus tropicalis)


name: ELANE, CTSG or PRTN3 binds bacteria (Canis familiaris)


name: Activated MET binds GAB1 and GRB2 (Gallus gallus)


name: H2O + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose <=> lactose + N-acetylneuraminate


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Gallus gallus)


name: ent-copalyl diphosphate = diphosphate + ent-pimara-9(11),15-diene


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA


name: Protein Kinase B (AKT) phosphorylates KSRP (Rattus norvegicus)


name: 12-phosphooxy-(9Z)-octadecenoate + H2O => 12-hydroxy-(9Z)-octadecenoate + phosphate


name: (2R)-S-methyl-3-phospho-1-thioglycerate + H2O => (2R)-S-methyl-1-thioglycerate + phosphate


name: H(+)(in) + malonate(out) + phosphate(in) => H(+)(out) + malonate(in) + phosphate(out)


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Homo sapiens)


name: Cleavage of C5 by C5 convertases (Gallus gallus)


name: (5E)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,5E)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: H2O + N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,2) = beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2)


name: MYO9B inactivates RHOA (Canis familiaris)


name: 5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine


name: a ganglioside GD1b (d18:1(4E)) + GDP-beta-L-fucose => a ganglioside Fuc-GD1b (d18:1(4E)) + GDP + H(+)


name: DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Sus scrofa)


name: H2O + O-(ADP-D-ribosyl)-L-tyrosyl-[protein] => ADP-D-ribose + L-tyrosyl-[protein]


name: AKT-phosphorylated FOXO3 translocates to cytosol (Gallus gallus)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Canis familiaris)


name: PTPN11 dephosphorylates RUNX1 (Rattus norvegicus)


name: H(+) + N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + UDP => N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine


name: NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)


name: HSP90 binds TBK1 and IRF3 (Homo sapiens)


name: Efflux of Glc from the endoplasmic reticulum (Homo sapiens)


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Rattus norvegicus)


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Sus scrofa)


name: COPI vesicle uncoating at the ER (Dictyostelium discoideum)


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Xenopus tropicalis)


name: Ubiquitinated DVL1 is degraded by the proteasome (Rattus norvegicus)


name: SPHK2 phosphorylates sphingoid (Caenorhabditis elegans)


name: chloride(in) + dopamine(in) + 2 Na(+)(in) => chloride(out) + dopamine(out) + 2 Na(+)(out)


name: 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Sus scrofa)


name: glutamate uptake by astrocytes (Xenopus tropicalis)


name: 1-O-(1Z-hexadecenyl)-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH <=> 1-O-(1Z-hexadecenyl)-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Danio rerio)


name: (9Z)-hexadecenoate + H2O = 10-hydroxyhexadecanoate


name: 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O => 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + formate + H(+)


name: 2-methylbutanamine + H2O + NADP(+) = 2-methylbutanal + H(+) + NADPH + NH4(+)


name: ATP + H(+) + IC-asc-C9 <=> diphosphate + IC-asc-C9-AMP


name: RHOA binds effectors at the plasma membrane (Caenorhabditis elegans)


name: diphosphate + N-geranyl-L-glutamate => (2E)-geranyl diphosphate + L-glutamate


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Caenorhabditis elegans)


name: Arresten binds integrin alpha1beta1 (Sus scrofa)


name: MDP elicits a NOD2 response (Mus musculus)


name: 2-acyl LPC is acylated to PC by LPCAT (Bos taurus)


name: SMURF1/2 ubiquitinates PRICKLE1 (Danio rerio)


name: ub UBXN7 is degraded by the 26S proteasome (Sus scrofa)


name: DRD2 antagonist drugs bind to DRD2 (Caenorhabditis elegans)


name: dTDP-6-deoxy-alpha-D-allose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-allose + H(+) + NADPH


name: 12-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Active calmodulin binds CAMK2 (Bos taurus)


name: 2-oxoglutarate + neamine => 6'-oxoparomamine + L-glutamate


name: CYP21A2 oxidises 17HPROG (Rattus norvegicus)


name: (3S)-citramalyl-CoA <=> 3-methylfumaryl-CoA + H2O


name: (2E,13Z)-docosadienoyl-CoA + H(+) + NADPH <=> (13Z)-docosenoyl-CoA + NADP(+)


name: 1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-O-octadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: O2 + octadecanoate + reduced [NADPH--hemoprotein reductase] => 18-hydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ARV1 transports CHOL from ER membrane to plasma membrane (Sus scrofa)


name: GGCT transforms gGluCys to OPRO (Caenorhabditis elegans)


name: HIF-alpha translocates from cytosol to nucleus (Canis familiaris)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Caenorhabditis elegans)


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2A (GRIN2A) (Sus scrofa)


name: 2 ADP + 2 H(+) + 2 L-glutamate + Ni-sirohydrochlorin a,c-diamide + 2 phosphate => 2 ATP + 2 H2O + 2 L-glutamine + Ni-sirohydrochlorin


name: SEC4C,D bind GOSR2 and STX5 (Rattus norvegicus)


name: 1-octanoylglycerol + H2O => glycerol + H(+) + octanoate


name: CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin (Mus musculus)


name: GABRR pentamers:GABA transports extracellular Cl- to cytosol (Caenorhabditis elegans)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)


name: Hh-Np is cleaved by ADAM17 to promote ligand shedding (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Rattus norvegicus)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate = ADP + ATP + 2 H(+)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Canis familiaris)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Xenopus tropicalis)


name: a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + 2 H2O + NAD(+) => a 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + H(+) + NADH + O2


name: an alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H(+) + UDP => an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-alpha-D-galactose


name: DeMQ10H2 is methylated to Q10H2 by COQ3 (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Rattus norvegicus)


name: PIAS4 SUMOylates IKBKG with SUMO1 (Xenopus tropicalis)


name: CDP-ethanolamine + L-serine => CMP + H(+) + L-serine-phosphoethanolamine


name: ATP(in) + H2O(in) + Zn(2+)(out) = ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in)


name: cyanidin 3-O-glucoside 6''-O-malonyltransferase activity


name: alizarin + UDP-alpha-D-glucose <=> 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP


name: Binding of cAMP to HCN channels (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Bos taurus)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Bos taurus)


name: 2-oxoglutarate + L-arginyl-[protein] + O2 => (3R)-3-hydroxy-L-arginyl-[protein] + CO2 + succinate


name: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine = H(+) + N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: H(+) + holo-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine) => 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(8),N'(8)-citryl-bis(spermidine)


name: ADRA1A,B,D bind ADR,NAd (Rattus norvegicus)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + H2O <=> 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H(+) + octadecanoate


name: Abortive termination of early transcription elongation by DSIF:NELF (Dictyostelium discoideum)


name: acetyl-CoA + N-terminal L-seryl-[histone H2A] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H2A]


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Saccharomyces cerevisiae)


name: KDM5A-D demethylate Me2K5-histone H3 (Homo sapiens)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Schizosaccharomyces pombe)


name: H(+)(out) + phosphate(out) + sulfate(in) => H(+)(in) + phosphate(in) + sulfate(out)


name: RNF181 polyubiquinates BCL10 (Sus scrofa)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Caenorhabditis elegans)


name: a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+)


name: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: HDAC10 deacetylates histone (Drosophila melanogaster)


name: GOT2 dimer deaminates L-Asp (Sus scrofa)


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Schizosaccharomyces pombe)


name: AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Homo sapiens)


name: F0 is cleaved, releasing F1, F2, F(110-136) (Homo sapiens)


name: CALCA(83-119) binds CALCA antibodies (Bos taurus)


name: MLCL is acylated to CL by LCLAT1 (ER) (Dictyostelium discoideum)


name: ATP + CoA + nicotinate = AMP + diphosphate + nicotinyl-CoA


name: Recruitment of GRB2 to p-PTK2 (Canis familiaris)


name: a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: Translocation of PLC-gamma1 to PIP2 (Canis familiaris)


name: PI4P transports from the Golgi membrane to the plasma membrane (Homo sapiens)


name: H(+) + N(6)-methyl-L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-homocysteine => L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-methionine


name: ADP(in) + AMP(out) => ADP(out) + AMP(in)


name: 2-glutathionyl-2-methylbut-3-en-1-ol => (3R)-3,4-epoxy-3-methylbut-1-ene + glutathione


name: 5'-deoxyadenosine + 5-(carboxymethyl)uridine(34) in tRNA + CoA + 2 H(+) + L-methionine => acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA


name: a 1,2-diacylglycerol + a fatty acid + H(+) => a triacyl-sn-glycerol + H2O


name: L-galactonate <=> 2-dehydro-3-deoxy-L-galactonate + H2O


name: 2-oxoglutarate + D-4-hydroxyphenylglycine => 4-hydroxyphenylglyoxylate + L-glutamate


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Canis familiaris)


name: p-S54-PDE4B hydrolyses cAMP (Drosophila melanogaster)


name: EDNRA,EDNRB bind EDNs (Canis familiaris)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Canis familiaris)


name: Melanin-concentrating hormone receptors bind MCH (Rattus norvegicus)


name: (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) <=> 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + NADH


name: acetyl-CoA + cyathatriol => 11-O-acetylcyathatriol + CoA


name: (S)-dihydroorotate + ubiquinone-8 => orotate + ubiquinol-8


name: alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP-alpha-D-mannose <=> alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: NAD(+) + UDP-N-acetyl-alpha-D-quinovosamine => H(+) + NADH + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose


name: a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b + CMP + H(+)


name: Activation of Ca permeable AMPA receptors (Homo sapiens)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Rattus norvegicus)


name: D-ribulose 5-phosphate + L-tyrosine <=> (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + formaldehyde + H(+) + H2O + hydroxyacetone + phosphate


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Homo sapiens)


name: A + H2O + thymine <=> 5-methylbarbiturate + AH2 + H(+)


name: a dipeptide(out) + 2 H(+)(out) => a dipeptide(in) + 2 H(+)(in)


name: WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it (Homo sapiens)


name: P2X1-mediated entry of Ca++ from plasma (Sus scrofa)


name: Transfer of ubiquitin from E1 to E2 (Homo sapiens)


name: 2-(2-methylsulfanyl)propylmaleate + H2O => 3-(3-methylsulfanyl)propylmalate


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Drosophila melanogaster)


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)


name: a ganglioside GA2 (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetyl-beta-D-galactosamine


name: Exocytosis of specific granule lumen proteins (Caenorhabditis elegans)


name: glycocholate(out) + n H(+)(out) <=> glycocholate(in) + n H(+)(in)


name: ACBD6 binds LCFA-CoA (Rattus norvegicus)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Bos taurus)


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Mus musculus)


name: NEU3 cleaves GM3 to form LacCer (plasma membrane) (Rattus norvegicus)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Gallus gallus)


name: (2E)-heptenoyl-CoA + H2O2 => heptanoyl-CoA + O2


name: (2R)-3-phosphoglycerate + ADP-alpha-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+)


name: a fatty acyl-CoA + sphinga-4E,14Z-dienine <=> an N-acyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: FADH2-C4alpha-hydroperoxide + NADPH + rifampicin = FADH2 + H(+) + H2O + NADP(+) + rifampicin hemiaminal


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Sus scrofa)


name: Activation of tandem pore domain in a weak inwardly rectifying  K+ channels (Danio rerio)


name: "With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen"


name: Autophosphorylation of LYN kinase (Canis familiaris)


name: 5-methylcytidine(1407) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(1407) in 16S rRNA + S-adenosyl-L-methionine


name: cyclohexylamine + H2O + O2 = cyclohexanone + H2O2 + NH4(+)


name: Release of E3 from polyubiquitinated substrate (Plasmodium falciparum)


name: Dynein motors transport misfolded proteins (Homo sapiens)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Rattus norvegicus)


name: all-trans-4,4'-diapolycopene + 4 FADH2 => 15-cis-4,4'-diapophytoene + 4 FAD + 4 H(+)


name: 2 H(+) + MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-penta-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 tRNA(Gly) => 2 glycyl-tRNA(Gly) + MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-tri-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc


name: L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: H2O + N,N-dimethylglycine + oxidized 2[4Fe-4S]-[ferredoxin] <=> formaldehyde + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin] + sarcosine


name: (2R,3R)-dihydromyricetin + 2-oxoglutarate + O2 => CO2 + H(+) + H2O + myricetin + succinate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol <=> a 1,2-diacylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Mus musculus)


name: H(+) + lactobionate => H2O + lactobiono-1,5-lactone


name: 2-oxoglutarate + melatonin + O2 => 2-hydroxymelatonin + CO2 + succinate


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: D-glucose + NAD(+) <=> D-glucono-1,5-lactone + H(+) + NADH


name: ligase activity, forming nitrogen-metal bonds


name: 7,7',9,9'-tetra-cis-lycopene + a quinol => 7,9,9'-tri-cis-neurosporene + a quinone


name: HNF1B-dependent synthesis of HNF6 protein (Homo sapiens)


name: (1S,2S,4S)-dihydrocarveol + NAD(+) => (1S,4S)-dihydrocarvone + H(+) + NADH


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Xenopus tropicalis)


name: S-(hydroxymethyl)mycothiol => formaldehyde + mycothiol


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Danio rerio)


name: botC LC cleaves target cell SNAP25 (Homo sapiens)


name: Release of activated MAD2 from kinetochores (Xenopus tropicalis)


name: A + all-trans-3,4-didehydro-13,14-dihydroretinol => AH2 + all-trans-3,4-didehydroretinol


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Sus scrofa)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Canis familiaris)


name: (2S)-versicolorone + NADP(+) <=> 1'-hydroxyversicolorone + H(+) + NADPH


name: Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Rattus norvegicus)


name: Gs activation by prostacyclin receptor (Mus musculus)


name: XRCC4:LIG4 ligates DNA DSB ends during NHEJ (Homo sapiens)


name: CO2 + L-ornithine + NH4(+) => 2 H(+) + H2O + L-citrulline


name: L-arabinitol + NAD(+) <=> H(+) + L-arabinose + NADH


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Bos taurus)


name: Formation of hydroxylysyl-pyridinoline cross-links (Rattus norvegicus)


name: factor XII -> factor XIIa (Xenopus tropicalis)


name: S2P hydrolyzes SREBP1A,1C,2 (Sus scrofa)


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Gallus gallus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Rattus norvegicus)


name: Constitutive phosphorylation by GSK3 (Sus scrofa)


name: ATP:coenzyme F420 adenylyltransferase activity


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Saccharomyces cerevisiae)


name: Regulation of KIF23 (MKLP1) by phosphorylation (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + tryptamine = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + serotonin


name: Immediate Early (IE) Gene Expression (Homo sapiens)


name: RNA Polymerase II Promoter Opening: First Transition (Saccharomyces cerevisiae)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O <=> 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate


name: 2-oxohexanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminohexanoate


name: D-mannonate + NADP(+) = D-mannuronate + H(+) + NADPH


name: (R)-S-lactoylglutathione => glutathione + methylglyoxal


name: (3S)-citryl-CoA + ADP + phosphate => ATP + citrate + CoA


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate = 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: E2F6 binds TFDP2 (Dictyostelium discoideum)


name: 3-(3-chloro-4-methoxylphenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + metoxuron + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing (Homo sapiens)


name: a globoside Gb4Cer (d18:1(4E)) + H(+) + UDP => a globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: chloride(out) + L-tryptophan(out) + 2 Na(+)(out) = chloride(in) + L-tryptophan(in) + 2 Na(+)(in)


name: guanosine + H(+) + H2O = NH4(+) + xanthosine


name: SFTPAs translocate from ER membrane to extracellular region (Homo sapiens)


name: crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) (Homo sapiens)


name: cyanate + H(+) + hydrogencarbonate <=> carbamate + CO2


name: Exocyst complex formation (Rattus norvegicus)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP-alpha-D-mannose <=> (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + GDP + H(+)


name: CTP(out) + dUTP(in) = CTP(in) + dUTP(out)


name: 2-methylpropanal + H(+) + NADH => isobutanol + NAD(+)


name: IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Gallus gallus)


name: Fusion of late-endosome derived vesicles at the TGN (Mus musculus)


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Rattus norvegicus)


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Mus musculus)


name: beta-lactose + H2O = beta-D-galactose + beta-D-glucose


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Saccharomyces cerevisiae)


name: thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Bos taurus)


name: 2''-O-acetyl-ADP-D-ribose + H2O = acetate + ADP-D-ribose + H(+)


name: GRB2:GAB1 binds to phosphorylated EGFR (Mus musculus)


name: Activated TRAF6 synthesizes free K63 linked pUb chains. (Gallus gallus)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Bos taurus)


name: (R)-benzodiazepinedione + dimethylallyl diphosphate => (2S,3R,11R)-aszonalenin + diphosphate


name: p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Sus scrofa)


name: ADP + H(+) + indoxyl sulfate(out) + phosphate => ATP + H2O + indoxyl sulfate(in)


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Xenopus tropicalis)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Saccharomyces cerevisiae)


name: Formation of Ragulator complex (Sus scrofa)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Xenopus tropicalis)


name: DSCAM/DSCAML1 homodimerization (Mus musculus)


name: Oligomerization of BCL10 and MALT1 (Homo sapiens)


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose => dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H2O


name: Benzene is hydroxylated to phenol (Xenopus tropicalis)


name: ATP + CoA + heptadecanoate => AMP + diphosphate + heptadecanoyl-CoA


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Sus scrofa)


name: Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Xenopus tropicalis)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O <=> [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phospho-L-serine


name: a plastoquinol + 4 H(+)(out) + 2 oxidized [2Fe-2S]-[ferredoxin] => a plastoquinone + 6 H(+)(in) + 2 reduced [2Fe-2S]-[ferredoxin]


name: (R)-carnitine(out) + 4-(trimethylamino)butanoate(in) => (R)-carnitine(in) + 4-(trimethylamino)butanoate(out)


name: Caspase mediated cleavage of APC (Bos taurus)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Danio rerio)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Xenopus tropicalis)


name: 4-hydroxybenzaldehyde + acetyl-CoA => 3-hydroxy-3-(4-hydroxyphenyl)propanoyl-CoA


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Canis familiaris)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Canis familiaris)


name: SOCS3 binds activated PTK6 (Rattus norvegicus)


name: 2alpha,7beta-dihydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2alpha-hydroxytaxusin + O2 + reduced [NADPH--hemoprotein reductase]


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Canis familiaris)


name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)


name: FOXO1,FOXO3 bind ABCA6 gene promoter (Homo sapiens)


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Caenorhabditis elegans)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Danio rerio)


name: CTP + UTP => cyclic CMP-UMP + 2 diphosphate


name: 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => androsta-1,4-diene-3,17-dione + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Activated protein C cleaves factor Va to factor Vi intermediate form (Mus musculus)


name: Defective GLB1 does not hydrolyse a glycosaminoglycan (Homo sapiens)


name: 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + H2O = beta-D-Gal-(1<->1')-Cer + H(+) + sulfate


name: RGS proteins bind GNB5 and CCT/TRiC (Drosophila melanogaster)


name: TFAP2C translocates to the nucleus (Mus musculus)


name: hederagenin + O2 + reduced [NADPH--hemoprotein reductase] => gypsogenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: mitomycin B + S-adenosyl-L-homocysteine => 6-demethylmitomycin B + S-adenosyl-L-methionine


name: Receptor CCR7 binds CCL19 and 21 ligands (Homo sapiens)


name: RNA polymerase II core promoter sequence-specific DNA binding


name: Gab2 binds the p85 subunit of Class 1A PI3 kinases (Homo sapiens)


name: ITPA hydrolyses ITP to IMP (Rattus norvegicus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: Acitretin binds to RAR:RXR (Mus musculus)


name: Formation of classical C5 convertase (Gallus gallus)


name: CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome (Drosophila melanogaster)


name: 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + H(+) + UDP => O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: 1-tetradecanoyl-sn-glycerol + phosphate => 1-tetradecanoyl-sn-glycerol 3-phosphate + H2O


name: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + 2-oxoglutarate + O2 => 4-O-deacetyl-16-O-demethylvindoline + CO2 + succinate


name: IL34 dimer:SDC1 binds CSF1R (Sus scrofa)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Dictyostelium discoideum)


name: NAGLU hydrolyses Heparan sulfate chain(4) (Drosophila melanogaster)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose = alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-Glc + GDP + H(+)


name: AR binds AR agonists (Xenopus tropicalis)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Schizosaccharomyces pombe)


name: 3-hydroxytetradecanoate + ATP + CoA = 3-hydroxytetradecanoyl-CoA + AMP + diphosphate


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Mus musculus)


name: 2-oxo-3-sulfanylpropanoate + L-kynurenine => H2O + kynurenate + L-cysteine


name: (2E,6E,10E,14E)-geranylfarnesol + H2O => 14betaH-scalarane-17alpha-19-diol


name: H2O + L-aspartate 4-semialdehyde + NAD(+) = 2 H(+) + L-aspartate + NADH


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Gallus gallus)


name: eIF2 activation (Dictyostelium discoideum)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: STEAP3-like proteins reduce Fe3+ to Fe2+ (Gallus gallus)


name: (+)-7-isojasmonate + ATP + L-isoleucine <=> AMP + diphosphate + H(+) + L-isoleucine-(+)-7-isojasmonate


name: H2O + sphing-4-enine 1-phosphate => phosphate + sphing-4-enine


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: cAMP dissociates PKA, promoting GLI processing (Danio rerio)


name: H(+) + H2O + S-adenosyl-L-homocysteine = NH4(+) + S-inosyl-L-homocysteine


name: MAP2K1 phosphorylates MAPK3 (Drosophila melanogaster)


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Rattus norvegicus)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA <=> 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase] = a 21-hydroxy-C21-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of the MCC complex (Dictyostelium discoideum)


name: The PRC1L4 complex binds the UXT gene promoter (Homo sapiens)


name: (E,E)-piperate + ATP + CoA = (E,E)-piperoyl-CoA + AMP + diphosphate


name: The Immunoglobulin of the BCR binds antigen (Homo sapiens)


name: Conversion of Glycerol to Glycerol-3-phosphate (Plasmodium falciparum)


name: (3S)-3-aminobutanoyl-CoA => (2E)-butenoyl-CoA + NH4(+)


name: A + D-gluconate => 2-dehydro-D-gluconate + AH2


name: UROD decarboxylates URO1 to COPRO1 (Xenopus tropicalis)


name: 4,5-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO2


name: RASA1 stimulates RAS GTPase activity (Danio rerio)


name: 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + CoA => (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Xenopus tropicalis)


name: AJUBA facilitates AURKA autophosphorylation (Xenopus tropicalis)


name: H2O + presqualene monophosphate => phosphate + presqualene alcohol


name: 1-hexadecanoyl-sn-glycero-3-phosphate + choline + H(+) => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: H(+) + holo-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8)-citryl-spermidine => 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(8)-citryl-spermidine


name: H2O + NADP(+) + senecionine N-oxide => NADPH + O2 + senecionine


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose <=> a beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)


name: PRKCI phosphorylates ELF3 (Canis familiaris)


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Mus musculus)


name: acetyl-CoA + 9 H(+) + 4 malonyl-CoA + 5 NADPH <=> 7-methylmellein + 3 CO2 + 5 CoA + 4 H2O + 5 NADP(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine = 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)


name: (9Z)-octadecenoyl-CoA + AH2 + O2 => (9Z,12Z)-octadecadienoyl-CoA + A + 2 H2O


name: Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Canis familiaris)


name: 2 a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycero-3-phospho-1D-myo-inositol


name: heme b + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> biliverdin IXalpha + CO + Fe(2+) + H(+) + 3 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 30-hydroxy-11-oxo-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] => glycyrrhetaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: "5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming)"


name: p-PKR dimer phosphorylates TP53 tetramer (Bos taurus)


name: TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex (Gallus gallus)


name: H(+) + indican + UDP => indoxyl + UDP-alpha-D-glucose


name: 7,9,9'-tri-cis-neurosporene + a quinone <=> 7,7',9,9'-tetra-cis-lycopene + a quinol


name: IL35 binds IL-12RB2:IL6ST receptor (Mus musculus)


name: acetyl-CoA + L-methionine sulfone => CoA + H(+) + N-acetyl-L-methionine sulfone


name: (-)-4'-methoxycyclopeptine + 2 AMP + 2 diphosphate + 2 H(+) + S-adenosyl-L-homocysteine => anthranilate + 2 ATP + O-methyl-L-tyrosine + S-adenosyl-L-methionine


name: 4,5,8-trihydroxycasbene + 2 NAD(+) => 2 H(+) + jolkinol C + 2 NADH


name: [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + n ADP + n H(+) + n phosphate => [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n) + n ATP + n D-aspartate


name: all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity


name: 2-oxoglutarate + L-hyoscyamine + O2 <=> (6S)-6-hydroxyhyoscyamine + CO2 + succinate


name: NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Bos taurus)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Bos taurus)


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Drosophila melanogaster)


name: 2-oxoglutarate + D-lysine <=> 6-amino-2-oxohexanoate + D-glutamate


name: TDG glycosylase mediated recognition and binding of an uracil opposite to a guanine (Homo sapiens)


name: Na(+)(out) + pyruvate(out) => Na(+)(in) + pyruvate(in)


name: soyasapogenol E UDP-glucosyltransferase activity


name: Pro-EGF is cleaved to form mature EGF (Homo sapiens)


name: Activation of cytosolic AMPK by phosphorylation (Rattus norvegicus)


name: H2O + N-decanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-decanoyl ethanolamine


name: adenine + H(+) + H2O <=> hypoxanthine + NH4(+)


name: HRH1 binds HRH1 inverse agonists (Homo sapiens)


name: RSF complex binds the centromere (Rattus norvegicus)


name: D-arginine(out) + L-ornithine(in) => D-arginine(in) + L-ornithine(out)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Bos taurus)


name: fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 (Canis familiaris)


name: AKT phosphorylates TSC2, inhibiting it (Gallus gallus)


name: PTPN22 dissociates from CSK (Gallus gallus)


name: SUMOylation of EP300 with SUMO1 (Sus scrofa)


name: Superoxide reduces cytochrome c (Gallus gallus)


name: Succinate <=> Fumarate (with FAD redox reaction on enzyme) (Dictyostelium discoideum)


name: 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose = 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP


name: glycine(in) + L-phenylalanine(out) => glycine(out) + L-phenylalanine(in)


name: SCF-beta-TrCP ubiquitinylates IkB (Homo sapiens)


name: a 2'-deoxyribonucleoside 5'-phosphate + ADP + H(+) => a 2'-deoxyribonucleoside + ATP


name: H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate => 2 GDP + 2 H(+)


name: Thrombin-activated PARs activate G12/13 (Canis familiaris)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Canis familiaris)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Drosophila melanogaster)


name: WWOX binds ERBB4s80 (Caenorhabditis elegans)


name: UBA1 adenylates ubiquitin in the cytosol (Saccharomyces cerevisiae)


name: RUNX1, SPI1 (PU.1), GATA2, TAL1 (SCL), FLI1, and MYB bind the CEBPA promoter (Homo sapiens)


name: CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 (Xenopus tropicalis)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADH <=> all-trans-lycopaoctaene + 2 diphosphate + NAD(+)


name: CoA + H(+) + N-tetracosenoyl-heptadecasphing-4-enine => heptadecasphing-4-enine + tetracosenoyl-CoA


name: mTORC1 phosphorylates MAF1 (Rattus norvegicus)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Xenopus tropicalis)


name: (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal => beta-cryptoxanthin + O2


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Danio rerio)


name: dihydrosanguinarine + H(+) + O2 => H2O2 + sanguinarine


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Dictyostelium discoideum)


name: 2,5-dioxopentanoate + H2O + NADP(+) => 2-oxoglutarate + 2 H(+) + NADPH


name: RAPGEF1 binds CRK,CRKL (Rattus norvegicus)


name: TDP1 and TDP2 process unligatable DSB ends (Dictyostelium discoideum)


name: L-proline(in) + Na(+)(in) => L-proline(out) + Na(+)(out)


name: Interaction of integrin alphaVbeta3 with Fibrillin (Rattus norvegicus)


name: 2,7-dihydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine <=> 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine


name: GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)


name: [phosphate](n) + GTP = [phosphate](n+1) + GDP


name: PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Canis familiaris)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Dictyostelium discoideum)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Caenorhabditis elegans)


name: Interaction of other tyrosine kinases with p-KIT (Danio rerio)


name: glycine + S-(1-hydroxy-3-methylhexan-3-yl)-L-cysteine => H2O + S-(1-hydroxy-3-methylhexan-3-yl)-L-cysteinylglycine


name: lorlatinib-resistant ALK mutants don't bind lorlatinib (Homo sapiens)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Saccharomyces cerevisiae)


name: a ganglioside GT1b (d18:1(4E)) + H2O = a ganglioside GD1b (d18:1(4E)) + N-acetylneuraminate


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Bos taurus)


name: PTEN undergoes monoubiquitination (Gallus gallus)


name: MRSBs reduce L-methyl-(R)-S-oxide to L-methionine (Danio rerio)


name: bis-D-fructose 2',1:2,1'-dianhydride + H2O => inulobiose


name: (E)-4-hydroxynon-2-enal + H2O + NADP(+) = (E)-4-hydroxynon-2-enoate + 2 H(+) + NADPH


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Saccharomyces cerevisiae)


name: RHOV binds GTP (Saccharomyces cerevisiae)


name: L-homocysteine + succinate => hydrogen sulfide + O-succinyl-L-homoserine


name: GGCT transforms gGluCys to OPRO (Homo sapiens)


name: indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose => (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP


name: Expression of EPHA4 in presomitic mesoderm (Homo sapiens)


name: guanosine(9) in tRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine


name: Phosphorylation of L1 by SRC (Rattus norvegicus)


name: Auto-ubiquitination of TRAF3 (Sus scrofa)


name: Recruitment of Grb2 to pFAK:NCAM1 (Bos taurus)


name: Inactive RAFs bind YWHAB (Xenopus tropicalis)


name: H2O + peregrinol diphosphate => diphosphate + viteagnusin D


name: beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> all-trans-zeaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: Ubiquitinated AXIN is degraded by the proteasome (Drosophila melanogaster)


name: 6-amino-6-deoxyfutalosine + H2O = adenine + dehypoxanthine futalosine


name: L-methionine(out) + S-methylmercury-L-cysteine(in) => L-methionine(in) + S-methylmercury-L-cysteine(out)


name: O2 + reduced [NADPH--hemoprotein reductase] + taurochenodeoxycholate = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + taurohyocholate


name: Disassembly of COPII coated vesicle (Canis familiaris)


name: biphenyl + H(+) + NADH + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: 5-methyl-3-oxohexanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxy-5-methylhexanoyl-[ACP] + NADP(+)


name: acetyl-CoA + D-glucosamine 6-phosphate <=> CoA + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: p-IRF7:p-IRF7 translocates to the nucleus (Bos taurus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Saccharomyces cerevisiae)


name: UDP-beta-L-arabinopyranose(in) + UMP(out) => UDP-beta-L-arabinopyranose(out) + UMP(in)


name: (R)-pantoate + ATP + beta-alanine <=> (R)-pantothenate + ADP + H(+) + phosphate


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Sus scrofa)


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Danio rerio)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + dodecanoyl-[ACP] = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + holo-[ACP]


name: 1-hexadecanoylglycerone 3-phosphate + tetradecan-1-ol => 1-O-tetradecylglycerone 3-phosphate + H(+) + hexadecanoate


name: UPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP (Drosophila melanogaster)


name: RHOA GAPs stimulate RHOA GTPase activity (Drosophila melanogaster)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA


name: GRKs bind ADRB2:Catecholamine (Sus scrofa)


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Homo sapiens)


name: (R)-glycerate + D-mannose => (2R)-2-O-(alpha-D-mannosyl)-glycerate + H2O


name: eNOS:NOSIP translocation from caveolae to intracellular compartments (Plasmodium falciparum)


name: (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O => (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Caenorhabditis elegans)


name: IL35 binds IL6ST:IL6ST receptor (Homo sapiens)


name: 5-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 5,20-dihydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Interaction of DAP12 and KIR2DS4 (Homo sapiens)


name: 2 (2E,6E)-farnesyl diphosphate => 15-cis-4,4'-diapophytoene + 2 diphosphate


name: H2O + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose => lactose + N-acetylneuraminate


name: dioscin + 2 H2O <=> diosgenin 3-O-beta-D-glucoside + 2 L-rhamnopyranose


name: DNA ligase I ligates single stranded nick in double stranded DNA (Caenorhabditis elegans)


name: H(+) + O-phospho-L-serine + sulfite = L-cysteate + phosphate


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Bos taurus)


name: (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al + 2-cis,4-trans-xanthoxin => 9-cis-violaxanthin + O2


name: Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Sus scrofa)


name: 2 Fe(III)-[cytochrome c] + hydrogen sulfide = 2 Fe(II)-[cytochrome c] + H(+) + sulfur


name: "sulfide-cytochrome-c reductase (flavocytochrome c)"


name: (2E,6E)-farnesyl diphosphate + H2O => (5S,9S,10S)-drim-7-en-11-ol + diphosphate


name: Proton-coupled di- and tri-peptide cotransport (Mus musculus)


name: Elongation of Extended Telomeric Chromosome End (Homo sapiens)


name: dextrin transmembrane transporter activity


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Sus scrofa)


name: Coumarin is 7-hydroxylated by CYP2A6 (Danio rerio)


name: ATP + H2O + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(in) => ADP + H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(out) + phosphate


name: ISGylation of host proteins (Mus musculus)


name: ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Xenopus tropicalis)


name: AMP + an acyl-CoA + H(+) => an acyl-AMP + CoA


name: CASP8 cleaves N4BP1 at D424, D490 (Sus scrofa)


name: OPTN binds polyUb-RIPK1 within the TNFR1 complex (Bos taurus)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Dictyostelium discoideum)


name: NR3C1 binds NR3C1 agonists (Danio rerio)


name: Proteasome degrades polyubiquitinated PTEN (Danio rerio)


name: PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Bos taurus)


name: CYP4A11 12-hydroxylates DDCX (Rattus norvegicus)


name: (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H2O => (3R)-hydroxy-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Mus musculus)


name: Elastin cross-linking by lysyl oxidase (Gallus gallus)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Rattus norvegicus)


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Bos taurus)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Drosophila melanogaster)


name: 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA


name: MIA2 and MIA3 dissociate from procollagen VII vesicle (Sus scrofa)


name: a ganglioside GM4 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => an N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP + H(+)


name: 1',3'-bis[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O = (9Z)-octadecenoate + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H(+)


name: L-pentahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate + H2O = beta-eudesmol + diphosphate


name: ADP + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] = AMP + H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase]


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Bos taurus)


name: HRH1 binds HRH1 inverse agonists (Canis familiaris)


name: PLK1 hyperphosphorylates Condensin II complex (Rattus norvegicus)


name: ATM phosphorylates MDM2 (Canis familiaris)


name: CHIT1 hydrolyses CHIT to 3xADGP (Rattus norvegicus)


name: H(+) + malonyl-CoA + S-anthraniloyl-L-cysteinyl-[PqsD protein] <=> (2-aminobenzoyl)acetyl-CoA + CO2 + L-cysteinyl-[PqsD protein]


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Sus scrofa)


name: dec-9-enoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> dec-9-ynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: L-histidyl-[protein] + lactose 6-phosphate(in) => lactose(out) + N(pros)-phospho-L-histidyl-[protein]


name: IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Mus musculus)


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Canis familiaris)


name: ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB (Homo sapiens)


name: a primary alcohol + NADP(+) => an aldehyde + H(+) + NADPH


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Bos taurus)


name: NAGLU hydrolyses heparan chain(2) (Drosophila melanogaster)


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Sus scrofa)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Gallus gallus)


name: p75NTR ICD signals to NF-kB (Sus scrofa)


name: Excess homocysteine yields homolanthionine and H2S (Drosophila melanogaster)


name: ISGylation of protein translation regulator 4EHP (Homo sapiens)


name: SMURFs ubiquitinate RUNX3 (Rattus norvegicus)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Caenorhabditis elegans)


name: AMP + H2O => adenosine + orthophosphate [NT5C1B] (Homo sapiens)


name: CO2 + L-tyrosine + NADH => L-arogenate + NAD(+)


name: 3' incision by ERCC5 (XPG) in TC-NER (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Dictyostelium discoideum)


name: trans-Golgi Network Coat Activation (Homo sapiens)


name: (24S)-hydroxycholesterol 24-sulfate + 3'-phosphoadenylyl sulfate <=> (24S)-hydroxycholesterol 3,24-disulfate + adenosine 3',5'-bisphosphate + H(+)


name: cytidine(34) in tRNA precursor + S-adenosyl-L-methionine = 5-methylcytidine(34) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Drosophila melanogaster)


name: JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Homo sapiens)


name: Diiodinated tyrosine can be deiodinated (Homo sapiens)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Bos taurus)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Sus scrofa)


name: CO2 + NH4(+) + sarcosine => 2 H(+) + H2O + N-carbamoylsarcosine


name: HDAC10 deacetylates histone (Bos taurus)


name: ATP + N-(D-ribulosyl)-cadaverine <=> ADP + H(+) + N-(3-O-phospho-D-ribulosyl)-cadaverine


name: L-tryptophan <=> 2-aminoprop-2-enoate + indole


name: Autoubiquitination of phospho-COP1(Ser-387 ) (Homo sapiens)


name: Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Bos taurus)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Rattus norvegicus)


name: SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Homo sapiens)


name: acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Drosophila melanogaster)


name: CoA + H(+) + N-acyl-4-hydroxyeicosasphinganine => (4R)-hydroxyeicosasphinganine + a fatty acyl-CoA


name: Gi,Go Heterotrimeric G-protein complex dissociates (Mus musculus)


name: Ubiquitination of phospho-p27/p21 (Canis familiaris)


name: EPHA binds TIAM1 (Caenorhabditis elegans)


name: RDH12 reduces atRAL to atROL (Bos taurus)


name: PPP5C dephosphorylates TP53BP1 (Dictyostelium discoideum)


name: BIL dissociates from GSTA1, FABP1 (Xenopus tropicalis)


name: tetrachloro-p-hydroquinone reductive dehalogenase activity


name: H2O + N(6)-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] = H(+) + L-lysyl-[protein] + lactate


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + ATP + L-cysteine => 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + H(+)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Canis familiaris)


name: UIMC1 and FAM175A bind DNA DSBs (Rattus norvegicus)


name: 7-hydroxy-chlorophyllide a oxygenase activity


name: a CMP-N-acyl-beta-neuraminate + H2O => an N-acylneuraminate + CMP + H(+)


name: (S)-reticuline + O2 => (S)-scoulerine + H(+) + H2O2


name: 20 H(+) + holo-[compactin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH = 9 CO2 + 9 CoA + dihydro-ML-236C-[compactin nonaketide synthase] + 6 H2O + 11 NADP(+)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Sus scrofa)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 => 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z)-docosapentaenoate


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Homo sapiens)


name: 3-oxochol-4-en-22-oyl-CoA + NAD(+) => 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH


name: UCKL1 phosphorylates urindine, cytidine (Bos taurus)


name: STING recruits TBK1 and STAT6 (Danio rerio)


name: 2 cob(I)alamin-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein] => 2 cob(II)alamin-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein]


name: GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Bos taurus)


name: Nuclear focus formation by interaction of chSNM1A with PIAS1 upon DNA lesion (Gallus gallus)


name: picrinine + S-adenosyl-L-methionine => ervincine + H(+) + S-adenosyl-L-homocysteine


name: 3-phenylpyruvate + glycine => glyoxylate + L-phenylalanine


name: SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Xenopus tropicalis)


name: CHEK1 phosphorylates TP53 (Rattus norvegicus)


name: 9,9'-di-cis-zeta-carotene + 2 a quinone => 7,7',9,9'-tetra-cis-lycopene + 2 a quinol


name: Fe(II)2-[transferrin] + H(+) + NAD(+) => Fe(III)2-[transferrin] + NADH


name: 2 glutathione + L-cystine <=> glutathione disulfide + 2 L-cysteine


name: a (2R)-2-methylacyl-CoA => a (2S)-2-methylacyl-CoA


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Saccharomyces cerevisiae)


name: anthranilate + 2 H(+) + NADPH + O2 = 2,3-dihydroxybenzoate + NADP(+) + NH4(+)


name: H2O + N(tele)-phospho-L-histidyl-[protein] <=> L-histidyl-[protein] + phosphate


name: Neuromedin-U receptors bind neuromedins U, S (Rattus norvegicus)


name: deacetylation of O-acetylserine and sulfhydrylation using CysK2 (Mycobacterium tuberculosis)


name: "bacterial ABC-type protein transporter"


name: Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Canis familiaris)


name: OSCAR binds collagen and SP-D (Canis familiaris)


name: GDP-fucose transmembrane transporter activity


name: (2E)-decenoyl-CoA + NADP(+) <=> (2E,4E)-decadienoyl-CoA + H(+) + NADPH


name: cytidine(48) in tRNA precursor + S-adenosyl-L-methionine => 5-methylcytidine(48) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol => a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: USP4 deubiquitinate TRAF2,TRAF6 (Sus scrofa)


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Caenorhabditis elegans)


name: Assembly of the pre-incision complex in TC-NER (Sus scrofa)


name: a (3R)-hydroxyacyl-[ACP] + NADP(+) <=> a 3-oxoacyl-[ACP] + H(+) + NADPH


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Xenopus tropicalis)


name: 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Sus scrofa)


name: alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Drosophila melanogaster)


name: 2-oxobutanoate + L-kynurenine <=> (2S)-2-aminobutanoate + H2O + kynurenate


name: N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: TPX2 promotes AURKA autophosphorylation (Bos taurus)


name: 1-(13Z-docosenoyl)-glycerol + H2O => (13Z)-docosenoate + glycerol + H(+)


name: Activated FGFR4:p-FRS binds GRB2:SOS1 (Caenorhabditis elegans)


name: GSS:Mg2+ dimer synthesizes GSH (Danio rerio)


name: Myelin components can interact with p75NTR:NgR:LINGO1 (Canis familiaris)


name: PTP1B dephosphorylates GHR (Mus musculus)


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Xenopus tropicalis)


name: ATP(in) + UDP(out) => ATP(out) + UDP(in)


name: 4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O


name: AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Homo sapiens)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Mus musculus)


name: NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 (Rattus norvegicus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O => (9Z)-octadecenoate + H(+) + sn-glycero-3-phospho-(1'-sn-glycerol)


name: Collagen XI cross-links with collagen II (Bos taurus)


name: chlorophyllide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 7(1)-hydroxychlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: The UDP/CysLT (P2Y17) receptor can bind UTP (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Drosophila melanogaster)


name: a 1-acylglycerone 3-phosphate + H(+) + NADPH => a 1-acyl-sn-glycero-3-phosphate + NADP(+)


name: 2 H(+) + 3 N-(2,3-dihydroxybenzoyl)-L-serine => enterobactin + 3 H2O


name: a cytidine in rRNA + S-adenosyl-L-methionine <=> an N(4)-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + L-threonyl-L-serine = L-serine + L-threonine


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Homo sapiens)


name: hydrolase activity, acting on acid sulfur-sulfur bonds


name: THTPA:Mg2+ hydrolyzes ThTP to TDP (Bos taurus)


name: (2E)-octenal + H2O + NADP(+) => (2E)-octenoate + 2 H(+) + NADPH


name: Activated FGFR4 phosphorylates FRS3 (Gallus gallus)


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) => 5,7-dihydroxy-4-methylphthalide + H2O


name: leukotriene C4 gamma-glutamyl transferase activity


name: DAG and Ca+2 bind to PKC and tether it to membrane (Caenorhabditis elegans)


name: 2-oxoglutarate + O2 + thebaine <=> CO2 + formaldehyde + oripavine + succinate


name: AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Bos taurus)