name: a 3-oxoacyl-CoA + CO2 + CoA => an acyl-CoA + H(+) + malonyl-CoA


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Caenorhabditis elegans)


name: 2-oxoglutarate + O2 + xanthine => CO2 + succinate + urate


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Danio rerio)


name: a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GP1c (d18:1(4E)) + CMP + H(+)


name: 2'-N-acetylparomamine + H2O => acetate + paromamine


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Xenopus tropicalis)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Homo sapiens)


name: a 5'-end triphospho-guanosine-ribonucleotide-snRNA + S-adenosyl-L-methionine => a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + S-adenosyl-L-homocysteine


name: GSDMD forms ring‐shaped oligomers  (Bos taurus)


name: 2-hydroxy-2,3-dihydrogenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase]


name: Activated protein C cleaves Factor Va intermediate form for Factor Va (Bos taurus)


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Sus scrofa)


name: TPI1 isomerizes GA3P to DHAP (Sus scrofa)


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Mus musculus)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Mus musculus)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Mus musculus)


name: SUMOylation of NOP58 with SUMO1 (Rattus norvegicus)


name: CBL monoubiquitinates activated MET (Bos taurus)


name: Activated FGFR3 binds PLCG1 (Rattus norvegicus)


name: acetate(in) + H(+)(in) => acetate(out) + H(+)(out)


name: 2-methyl-cis-aconitate + H2O => 2-methylcitrate


name: a 3beta-hydroxy-4,4-dimethylsteroid + H(+) + NADH + O2 = a 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + H2O + NAD(+)


name: cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine <=> 5-methylcytidine(72) in tRNA(Thr) + H(+) + S-adenosyl-L-homocysteine


name: Transport of L1 into endosomes (Drosophila melanogaster)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Mus musculus)


name: H2O + N-formyl-L-methionine = formate + L-methionine


name: Surface deployment of platelet dense granule membrane components (Dictyostelium discoideum)


name: GATA4 and NKX2-5 bind the HAND1 gene (Homo sapiens)


name: ATR phosphorylates TP53 (Xenopus tropicalis)


name: 2-oxoglutarate + L-dopa <=> 3-(3,4-dihydroxyphenyl)pyruvate + L-glutamate


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Dictyostelium discoideum)


name: TDG excises 5-formylcytosine (Homo sapiens)


name: E2F1 gene transcription is inhibited by E2F6 (Homo sapiens)


name: 2 2',3,4-trihydroxy-trans-chalcone + 2 H(+) + O2 = 2 3',4'-dihydroxyaurone + 2 H2O


name: H(+) + NADH + O2 + terephthalate => (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)


name: PIP3 recruits AKT to the membrane (Danio rerio)


name: Aquaporin-7 passively transports glycerol out of cell (Gallus gallus)


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Rattus norvegicus)


name: 4 Fe(2+) + 6 H2O + O2 => 12 H(+) + 4 iron(III) oxide-hydroxide


name: O2 + reduced [NADPH--hemoprotein reductase] + teasterone <=> 7-oxateasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Danio rerio)


name: SUMOylation of RXRA with SUMO1 (Bos taurus)


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Sus scrofa)


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Bos taurus)


name: 4-(trimethylamino)butanoyl-CoA + AMP + diphosphate => 4-(trimethylamino)butanoate + ATP + CoA


name: Recruitment of TBK1/IKK epsilon to K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR4 followed by their activation (Mus musculus)


name: EOMES, SMAD2,3, and GATA6 bind the CXCR4 gene (Homo sapiens)


name: 2-oxopentanoate + N(omega),N(omega)-dimethyl-L-arginine => 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminopentanoate


name: Laminins bind Nidogens 1, 2 (Homo sapiens)


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Sus scrofa)


name: A + crepenynate + 2 H2O => (9Z,12Z)-octadecadienoate + AH2 + O2


name: JAK2-activated MAPKs phosphorylate YBX1 (Xenopus tropicalis)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG2 (Drosophila melanogaster)


name: Autophosphorylation of PAK1 (Mus musculus)


name: alpha-D-xylose 1-phosphate + H(+) + UTP <=> diphosphate + UDP-alpha-D-xylose


name: PGM2:Mg2+ isomerises R1P to R5P (Bos taurus)


name: N-acetyl-L-aspartate(out) + 3 Na(+)(out) <=> N-acetyl-L-aspartate(in) + 3 Na(+)(in)


name: acetyl-CoA + N-acetylneuraminate <=> CoA + N-acetyl-4-O-acetylneuraminate


name: ATP + L-glutamate + tyramine => ADP + gamma-L-glutamyltyramine + H(+) + phosphate


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Dictyostelium discoideum)


name: H2O + L-lysine + NAD(+) <=> (S)-2-amino-6-oxohexanoate + H(+) + NADH + NH4(+)


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Mus musculus)


name: 3,4,5-trihydroxybenzoate + UDP-alpha-D-glucose = 1-O-galloyl-beta-D-glucose + UDP


name: Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Canis familiaris)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Rattus norvegicus)


name: 4',4'-dihydroxyechinenone => canthaxanthin + H2O


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Sus scrofa)


name: UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG (Homo sapiens)


name: GRKs bind ADRB2:Catecholamine (Homo sapiens)


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Mus musculus)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Xenopus tropicalis)


name: PDCD1 binds PDCD1 inhibitors (Homo sapiens)


name: a quinone + sn-glycerol 3-phosphate <=> a quinol + dihydroxyacetone phosphate


name: SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp (Danio rerio)


name: GBF1 stimulates ARF nucleotide exchange (Dictyostelium discoideum)


name: ATG12 forms a thioester bond with ATG7 dimer (Drosophila melanogaster)


name: 3'-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] => 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: acetyl-CoA + 3 malonyl-CoA + 2 S-adenosyl-L-methionine <=> 3,5-dimethylorsellinate + 3 CO2 + 4 CoA + 2 S-adenosyl-L-homocysteine


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Mus musculus)


name: (20S)-ginsenoside Rg3 + H2O => (20S)-ginsenoside Rh2 + D-glucose


name: Inactivation of Rho-GTP by p190RhoGAP (Mus musculus)


name: 4-methylene-L-glutamate + ATP + NH4(+) = 4-methylene-L-glutamine + AMP + diphosphate + H(+)


name: Parenchymal atROL translocates to HSCs (Mus musculus)


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Sus scrofa)


name: FMN-N(5)-peroxide + thymine = (Z)-2-methylureidoacrylate + FMN-N(5)-oxide + 2 H(+)


name: 1,2-di-(9Z-octadecenoyl)-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + UDP-alpha-D-galactose


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Drosophila melanogaster)


name: H2O + L-alanyl-L-histidine <=> L-alanine + L-histidine


name: trans-4-hydroxy-L-prolyl-[protein] + UDP-beta-L-arabinofuranose = H(+) + O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-prolyl-[protein] + UDP


name: CYP7B1 7-hydroxylates 25OH-CHOL (Sus scrofa)


name: guanosine + NAD(+) <=> H(+) + N(2)-(ADP-D-ribosyl)-guanosine + nicotinamide


name: Opioid dissociates from MOR (Rattus norvegicus)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Xenopus tropicalis)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Homo sapiens)


name: NADP(+) + octan-1-ol = H(+) + NADPH + octanal


name: Interaction of IRF9 with p-STAT2:p-STAT1 (Xenopus tropicalis)


name: (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate <=> 3-hydroxypropyl isothiocyanate + sulfate


name: Excess cysteine yields lanthionine and H2S (Caenorhabditis elegans)


name: histone arginine N-methyltransferase activity


name: Association of Emi1 with Cdc20 (Mus musculus)


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: LIPs hydrolyse TG to DAG and RCOOH (Bos taurus)


name: (9Z,12Z)-hexadecadienoyl-CoA + A + 2 H2O => (9Z)-hexadecenoyl-CoA + AH2 + O2


name: Glucagon binds to Glucagon receptor (Sus scrofa)


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Homo sapiens)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Sus scrofa)


name: 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose = (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + H(+) + UDP


name: a 2,3-saturated acyl-CoA + NADP(+) <=> a 2,3-dehydroacyl-CoA + H(+) + NADPH


name: 4'-O-methylnorbelladine + H(+) + S-adenosyl-L-homocysteine => norbelladine + S-adenosyl-L-methionine


name: DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs (Homo sapiens)


name: SLC29A1 transports RBV from extracellular region to cytosol (Drosophila melanogaster)


name: ESTG binds ESR2:chaperone complex (Sus scrofa)


name: Recruitment of GADS:SLP-76 to p-5Y-LAT (Gallus gallus)


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-glycine


name: Recruitment of FAK to NCAM1:Fyn in lipid rafts (Homo sapiens)


name: Transfer of ubiquitin from E1 to E2 (Xenopus tropicalis)


name: NTPDase4 hydrolyzes nucleoside triphosphates (Homo sapiens)


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Rattus norvegicus)


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Xenopus tropicalis)


name: JNK phosphorylates BIM, BAD and other targets (Mus musculus)


name: IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37 (Xenopus tropicalis)


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Xenopus tropicalis)


name: SeO3(2-) is reduced to H2Se by TXNRD1 (Homo sapiens)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Mus musculus)


name: Defective SLC34A3 does not cotransport Pi, 2Na+ (Homo sapiens)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 = 4-[(E)-2-isocyanoethenyl]phenol + 2 CO2 + H2O + succinate


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: diphosphate + ilicicolinate B => (2E,6E)-farnesyl diphosphate + orsellinate


name: CSNK1D phosphorylates SEC23 (Homo sapiens)


name: H(+) + Na(+)(out) + 2 phosphate => diphosphate + H2O + Na(+)(in)


name: 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol => 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Dictyostelium discoideum)


name: AKR1B15 reduces EST17b to E1 (Dictyostelium discoideum)


name: 26-hydroxyhexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] => 26-oxohexacosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: daidzein 7-O-beta-D-glucoside + H2O => beta-D-glucose + daidzein + H(+)


name: MBTPS1 (S1P) cleaves CREB3L3 (Bos taurus)


name: Cleavage of collagen VII NC2 region by BMP1 (Sus scrofa)


name: G-protein coupled bile acid receptor binds lithocholic acid (Xenopus tropicalis)


name: CPTP transports C1P from plasma membrane to Golgi membrane (Bos taurus)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Mus musculus)


name: TNFSF11 binds TNFRSF11A, B (Xenopus tropicalis)


name: ATP + glycyl-L-methionine(out) + H2O <=> ADP + glycyl-L-methionine(in) + H(+) + phosphate


name: (Z)-2-methylureidoacrylate + H(+) + H2O = (Z)-2-methylaminoacrylate + CO2 + NH4(+)


name: Ubiquitination of NEMO by TRAF6 (Canis familiaris)


name: beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-dodecanoylsphing-4-enine


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Canis familiaris)


name: PAK1 binds ARHGEF6 (Caenorhabditis elegans)


name: 24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: (E)-coniferol + UDP-alpha-D-glucose => 4-O-(beta-D-glucosyl)-(E)-coniferol + H(+) + UDP


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Drosophila melanogaster)


name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Saccharomyces cerevisiae)


name: Self-ubiquitination of RNF41 (Dictyostelium discoideum)


name: Formation of the closed pre-initiation complex (Drosophila melanogaster)


name: hexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 9-hydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Canis familiaris)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Canis familiaris)


name: 3-sulfino-L-alanine + H2O <=> H(+) + L-alanine + sulfite


name: glycodeoxycholate + H2O = deoxycholate + glycine


name: HMG CoA => acetoacetic acid + acetyl CoA (Xenopus tropicalis)


name: Caspase mediated cleavage of APC (Canis familiaris)


name: a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-alpha-D-glucose <=> a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside + H(+) + UDP


name: 2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + hexadecanoate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: galactarate(in) + H(+)(in) = galactarate(out) + H(+)(out)


name: AMPK-alpha2 phosphorylates TBC1D1 (Homo sapiens)


name: diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein] => N(pros)-phospho-L-histidyl-[protein] + N,N'-diacetylchitobiose(out)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+)


name: H2O + tuberculosinyl diphosphate => diphosphate + tuberculosinol


name: ADO oxidises 2AET to HTAU (Canis familiaris)


name: 3-oxotetradecanoyl-CoA + CO2 + CoA => dodecanoyl-CoA + H(+) + malonyl-CoA


name: an N-(ultra-long-chain-acyl)-sphingoid base + CoA + H(+) => a sphingoid base + an ultra-long-chain fatty acyl-CoA


name: UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG (Mus musculus)


name: D-alanine + L-glutamine <=> gamma-L-glutamyl-D-alanine + NH4(+)


name: acetyl-CoA + D-aspartate <=> CoA + H(+) + N-acetyl-D-aspartate


name: all-trans-retinol + an acyl-CoA <=> an all-trans-retinyl ester + CoA


name: Hh C-terminal fragments are degraded by the proteasome (Rattus norvegicus)


name: 19-hydroxy-prostaglandin I2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + prostaglandin I2 + reduced [NADPH--hemoprotein reductase]


name: CO binds to free ferrohemoglobin (Homo sapiens)


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Gallus gallus)


name: diphosphate + isopimara-8(14),15-diene => 9alpha-copalyl diphosphate


name: D-galactono-1,4-lactone + H2O = D-galactonate + H(+)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Homo sapiens)


name: SCF(SKP2) complex binds RUNX2 (Bos taurus)


name: nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) (Homo sapiens)


name: pro-SFTPB translocates from ER membrane to multivesicle body (Rattus norvegicus)


name: apigenin 7-O-beta-D-glucoside + malonyl-CoA <=> apigenin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-choline = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen (Rattus norvegicus)


name: 2-acetamidofluorene + H2O + NADP(+) => H(+) + N-hydroxy-2-acetamidofluorene + NADPH


name: P2Y14 receptor can bind to UDP-glucose (Canis familiaris)


name: alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose => alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: (+)-artemisinic aldehyde + O2 + reduced [NADPH--hemoprotein reductase] => (+)-artemisinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a D-alpha-amino acid + H2O + O2 => a 2-oxocarboxylate + H2O2 + NH4(+)


name: L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine


name: nicotinate(out) + orotate(in) => nicotinate(in) + orotate(out)


name: SHC1 binds to the phosphorylated EGF receptor:ligand complex (Canis familiaris)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: 2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer (Homo sapiens)


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Mus musculus)


name: Vamp2 associated secretory vesicle to plasma membrane transport (Sus scrofa)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Sus scrofa)


name: glutathione + H(+) + sulfite => glutathione S,S-dioxide + H2O


name: RAS:GTP binds RAL GDS proteins (Bos taurus)


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]3 + H(+) => Fe(III)-enterobactin + H2O


name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region (Gallus gallus)


name: NPC2 binds CHOL (Drosophila melanogaster)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Xenopus tropicalis)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Schizosaccharomyces pombe)


name: (S)-S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine => 3-O-acetylpapaveroxine + H(+) + S-adenosyl-L-homocysteine


name: 1-(13Z-docosenoyl)-glycerol + H2O <=> (13Z)-docosenoate + glycerol + H(+)


name: NFE2L2 binds the TALDO1 gene (Homo sapiens)


name: Active calmodulin binds CAMK2 (Rattus norvegicus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + octadecanoyl-CoA <=> 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phospho-L-serine + CoA


name: Cdt1 is displaced from the pre-replicative complex. (Sus scrofa)


name: CHOL translocates from lysosome membrane to ER membrane (Caenorhabditis elegans)


name: D-threonine(out) + L-alanine(in) <=> D-threonine(in) + L-alanine(out)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Bos taurus)


name: Autophosphorylation of LYN kinase (Sus scrofa)


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Xenopus tropicalis)


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Mus musculus)


name: ATP + H2O + L-tryptophan => AMP + D-tryptophan + diphosphate + H(+)


name: cinerin I + CoA => (1R,3R)-chrysanthemoyl-CoA + (Z,S)-cinerolone


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Canis familiaris)


name: ortho-trichlorophenol reductive dehalogenase activity


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)


name: [(1->6)-alpha-D-glucosyl](n) + sucrose = (1->3)-alpha-D-glucosyl-[(1->6)-alpha-D-glucosyl](n) + D-fructose


name: hydroperoxy icosatetraenoate dehydratase activity


name: ADAT1 deaminates adenosine-37 in tRNA(Ala) (Homo sapiens)


name: Phosphorylation of MDM4 by ATM (Homo sapiens)


name: (indol-3-yl)butanoyl-L-cysteine + AMP + diphosphate + H(+) => (indol-3-yl)butanoate + ATP + L-cysteine


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Rattus norvegicus)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)


name: GRB2:SOS1 complex binds phosphorylated EGFR:ERBB2 heterodimer (Homo sapiens)


name: EDTA + 2 FMNH2 + 2 O2 => ethylenediaminediacetate + 2 FMN + 2 glyoxylate + 3 H(+) + 2 H2O


name: 1',3'-bis[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O <=> (9Z)-octadecenoate + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H(+)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Gallus gallus)


name: ATP + L-ribulose => ADP + H(+) + L-ribulose 5-phosphate


name: S-adenosyl-L-methionine + TRIBOA beta-D-glucoside <=> DIMBOA beta-D-glucoside + H(+) + S-adenosyl-L-homocysteine


name: P4HB forms mixed disulphides with Hh precursors (Rattus norvegicus)


name: GNB2L1 binds IKKA:IKKB:NEMO (Drosophila melanogaster)


name: 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+) => 1,2-dioctanoyl-sn-glycerol + CDP-choline


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: Formation of the GCN5-ATAC complex (Gallus gallus)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Xenopus tropicalis)


name: Autocatalytic activation of MMP3 (Drosophila melanogaster)


name: Frataxin binds iron (Dictyostelium discoideum)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Bos taurus)


name: H2O + N-hexadecanoylsphing-4-enine <=> hexadecanoate + sphing-4-enine


name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region (Caenorhabditis elegans)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Rattus norvegicus)


name: IKBA is phosphorylated by Phospho IKKB kinase (Drosophila melanogaster)


name: IL36RN, IL1F10 bind IL1RL2 (Xenopus tropicalis)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Saccharomyces cerevisiae)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Mus musculus)


name: dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+) => dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: 3 a quinol + protoporphyrin IX => 3 a quinone + protoporphyrinogen IX


name: H(+)(out) + myo-inositol(out) => H(+)(in) + myo-inositol(in)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Sus scrofa)


name: acetyl-CoA + H(+) + 3 malonyl-CoA + S-adenosyl-L-methionine => 3-methylorsellinate + 3 CO2 + 4 CoA + S-adenosyl-L-homocysteine


name: AH2 + O2 + progesterone => A + H2O + testosterone acetate


name: a 1,2-diacyl-sn-glycerol + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + N-acyl-15-methylhexadecasphing-4-enine


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine <=> a diacylglycerol + an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine


name: 3,4-dihydroxybenzoate + O2 <=> 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)


name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen


name: "Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2"


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Homo sapiens)


name: PIAS1 SUMOylates THRB with SUMO1. (Bos taurus)


name: acetyl-CoA + N-terminal L-alanyl-[ribosomal protein uS5] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein uS5]


name: AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Mus musculus)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Bos taurus)


name: ADP + D-glucose = AMP + D-glucose 6-phosphate + H(+)


name: KDM1A is recruited to MYC and BCL2 genes (Sus scrofa)


name: 20-hydroxy-leukotriene B4 + NADP(+) = 12-oxo-20-hydroxy-leukotriene B4 + H(+) + NADPH


name: 3-amino-5-hydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate => 3-amino-5-hydroxybenzoate + ATP + holo-[aryl-carrier protein]


name: cortisone + H(+) + NADPH = 20beta-dihydrocortisone + NADP(+)


name: 3-(methylsulfanyl)acryloyl-CoA + 2 H2O <=> acetaldehyde + CO2 + CoA + methanethiol


name: 2-oxo-AMP + diphosphate + H(+) => 2-oxo-ATP + H2O


name: BPHL hydrolyses VACV to ACV (Homo sapiens)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Danio rerio)


name: PPP5C dephosphorylates TP53BP1 (Schizosaccharomyces pombe)


name: (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate <=> 2-succinylbenzoate + H2O


name: CYP4F2, 4F3 20-hydroxylate LTB4 (Canis familiaris)


name: (13Z)-docosenoyl-CoA + sphing-4-enine <=> CoA + H(+) + N-(13Z-docosenoyl)-sphing-4-enine


name: CYP4F12 18-hydroxylates ARA (Bos taurus)


name: dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine <=> dTDP-alpha-D-forosamine + H(+) + S-adenosyl-L-homocysteine


name: a cytidine in tRNA + acetyl-CoA + ATP + H2O <=> ADP + an N(4)-acetylcytidine in tRNA + CoA + H(+) + phosphate


name: RNF41 ubiquitinates ERBB3 (Homo sapiens)


name: DHFR dimer reduces FOLA to DHF (Danio rerio)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Drosophila melanogaster)


name: glutamate-gated calcium ion channel activity


name: 1-octadecanoyl-sn-glycero-3-phosphoserine + 10-hydroxyoctadecanoate + H(+) => 1-octadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Sus scrofa)


name: 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA => 3-oxopropanoyl-CoA + methanethiol


name: Activation of Edited Kainate receptors (Gallus gallus)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Caenorhabditis elegans)


name: DHNTP is dephosphorylated by PTPS to PTHP (Sus scrofa)


name: SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Bos taurus)


name: beta-D-galactose + beta-D-glucose => beta-lactose + H2O


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Xenopus tropicalis)


name: (3S)-hydroxydecanoyl-CoA <=> (2E)-decenoyl-CoA + H2O


name: acrylate + H(+) + NADH <=> NAD(+) + propanoate


name: Anti-MET small tyrosine kinase inhibitors bind MET (Xenopus tropicalis)


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + 2 AMP + 2 diphosphate + H(+) + H2O + NADP(+) => 2 ATP + L-proline + L-tryptophan + NADPH


name: cadherin binding involved in cell-cell adhesion


name: N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + 3 UDP-N-acetyl-alpha-D-galactosamine => [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + 3 H(+) + 3 UDP


name: PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Mus musculus)


name: 9-octadecanoyloxy-octadecanoate + H2O => 9-hydroxy-octadecanoate + H(+) + octadecanoate


name: (R)-5-phosphomevalonate + ATP <=> ADP + CO2 + isopentenyl phosphate + phosphate


name: GALNT3 transfers GalNAc to FGF23 (Drosophila melanogaster)


name: H(+) + NADPH + yaequinolone D = H2O + NADP(+) + penigequinolone A


name: Inactive G alpha (i) reassociates with G beta:gamma (Sus scrofa)


name: Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Rattus norvegicus)


name: TRPA1 tetramer binds TRPA1 antagonists (Gallus gallus)


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Bos taurus)


name: acetyl-CoA + 3 malonyl-CoA + 2 S-adenosyl-L-methionine = 3,5-dimethylorsellinate + 3 CO2 + 4 CoA + 2 S-adenosyl-L-homocysteine


name: XDH oxidizes xanthine to form urate (Dictyostelium discoideum)


name: PIAS1 SUMOylates DDX5 with SUMO2 (Drosophila melanogaster)


name: Nephrin interacts with Podocin (Sus scrofa)


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Gallus gallus)


name: a long-chain fatty aldehyde + CoA + NADP(+) => a long-chain fatty acyl-CoA + H(+) + NADPH


name: Nuclear translocation of catalytic domain of Mst3 (Homo sapiens)


name: L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2


name: GLUT7 and GLUT11 transport glucose and fructose (Dictyostelium discoideum)


name: a uridine in tRNA + S-adenosyl-L-methionine <=> a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + H(+) + S-methyl-5'-thioadenosine


name: alpha-D-glucose 1-phosphate + alpha-maltopentaose => alpha-maltohexaose + phosphate


name: BAP1 binds BAP1-interacting complex (Bos taurus)


name: CDK6 inhibitors bind CDK6 (Homo sapiens)


name: RHOJ GEFs activate RHOJ (Drosophila melanogaster)


name: 2-methyl-2-(methylamino)propanoate(out) + chloride(out) + 2 Na(+)(out) <=> 2-methyl-2-(methylamino)propanoate(in) + chloride(in) + 2 Na(+)(in)


name: RHOB GEFs activate RHOB (Xenopus tropicalis)


name: ATP + H2O + selenate(out) => ADP + H(+) + phosphate + selenate(in)


name: PTK6 phosphorylates BCAR1 (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = (2Z,6E,10E)-geranylgeranyl diphosphate + diphosphate


name: MADCAM1-1 binds Integrin alpha4beta7 (Sus scrofa)


name: Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Bos taurus)


name: ADA catalyzes the deamination of (deoxy)adenosine (Mus musculus)


name: RNF41 ubiquitinates ERBB3 (Drosophila melanogaster)


name: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Plasmodium falciparum)


name: butanoate(out) + Na(+)(out) => butanoate(in) + Na(+)(in)


name: Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) (Danio rerio)


name: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA


name: Endosome acidification (Xenopus tropicalis)


name: PLK3 phosphorylates CDC25C (Dictyostelium discoideum)


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 1-O-methyl-12-hydroperoxy-20-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate <=> H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate


name: a trans-Delta(2)-meromycolyl-[ACP] + H(+) + NADH => a 2,3-saturated meromycolyl-[ACP] + NAD(+)


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Xenopus tropicalis)


name: 1-O-(1Z-hexadecenyl)-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH => 1-O-(1Z-hexadecenyl)-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: Arachidonic acid  is converted to 12-oxoETE by ALOX12 (Rattus norvegicus)


name: GDP + H(+) + oxidized coenzyme F420-2 + phosphate => GTP + L-glutamate + oxidized coenzyme F420-1


name: SOS binds Grb2 bound to pFAK:NCAM1 (Gallus gallus)


name: (22S)-22-hydroxy-campesterol C-23 hydroxylase activity


name: A + dihydrobisanhydrobacterioruberin => AH2 + bisanhydrobacterioruberin


name: RAC2 GAPs stimulate RAC2 GTPase activity (Sus scrofa)


name: Phosphorylation of BIM by JNK (Canis familiaris)


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Canis familiaris)


name: IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Canis familiaris)


name: (20S)-ginsenoside Rb1 + 2 H2O = (20S)-ginsenoside Rg3 + 2 D-glucose


name: ATP + Co(2+)(out) + H2O <=> ADP + Co(2+)(in) + H(+) + phosphate


name: H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline => 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Dephosphorylation of Gab1 by SHP2 (Rattus norvegicus)


name: Recruitment of SLP-76 to Gads (Canis familiaris)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Mus musculus)


name: Fusion of COPII vesicle with Golgi complex (Canis familiaris)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-4-deoxy-4-formamido-beta-L-arabinose = 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + UDP


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Drosophila melanogaster)


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + [thyroglobulin]-3-iodo-L-tyrosine + H2O2 => [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O


name: SUMOylation of PCNA with SUMO1 (Saccharomyces cerevisiae)


name: an N-acylsphing-4-enine + UDP-alpha-D-xylose <=> a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP


name: an alditol + NAD(+) => an aldose + H(+) + NADH


name: (3S)-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+)


name: RAC3 GAPs stimulate RAC3 GTPase activity (Canis familiaris)


name: 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine


name: Activated FGFR2 phosphorylates FRS3 (Gallus gallus)


name: 1-cyclohexylethanone + H(+) + NADPH + NH4(+) => 1-cyclohexylethanamine + H2O + NADP(+)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Homo sapiens)


name: NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Drosophila melanogaster)


name: INPP5E translocates to the primary cilium (Sus scrofa)


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Drosophila melanogaster)


name: H(+) + N,N-dihydroxy-L-tyrosine => (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Sus scrofa)


name: factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) (Sus scrofa)


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Drosophila melanogaster)


name: p-CD19:VAV binds PI3K and GRB2 (Sus scrofa)


name: PPARA:RXRA binds Corepressors of PPARA (Xenopus tropicalis)


name: (S)-2-hydroxypropyl-coenzyme M = (S)-1,2-epoxypropane + coenzyme M


name: PDE6 hydrolyses cGMP to GMP (Xenopus tropicalis)


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Danio rerio)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Gallus gallus)


name: Multiubiquitination of APC/C-associated Cdh1 (Bos taurus)


name: 2-hydroxytetracosenoyl-CoA + sphinganine = CoA + H(+) + N-(2-hydroxytetracosenoyl)-sphinganine


name: H2O + NAD(+) + quinoline-2,8-diol => H(+) + NADH + O2 + quinolin-2-ol


name: ATP + D-sedoheptulose 7-phosphate <=> ADP + D-sedoheptulose 1,7-bisphosphate + H(+)


name: H(+) + NADPH + NH4(+) + pentan-3-one => 3-aminopentane + H2O + NADP(+)


name: RNA Polymerase II Promoter Opening: First Transition (Gallus gallus)


name: Inactivation of APC/C via CDC20 sequestration (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 3-octadecanoyl-sn-glycerol = 1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + CoA


name: pseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylpseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-homocysteine


name: NPAS4 stimulates FOS gene expression (Homo sapiens)


name: cinerin II + CoA => (1R,3R)-pyrethroyl-CoA + (Z,S)-cinerolone


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-heptadecanoyl-sn-glycero-3-phosphoserine + H(+) => 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Canis familiaris)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Bos taurus)


name: RNF146 binds RibC-AXIN:TNKS complex (Sus scrofa)


name: 5-PP-IP5 transports from the nucleus to the cytosol (Homo sapiens)


name: dimethylallyl diphosphate + isopentenyl diphosphate = (2E)-geranyl diphosphate + diphosphate


name: Receptor CCR10 binds CCL27 and 28 ligands (Canis familiaris)


name: Autocatalytic activation of MMP3 (Mus musculus)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Bos taurus)


name: acetyl-CoA + L-alpha-phenylglycine <=> CoA + H(+) + N-acetyl-L-alpha-phenylglycine


name: Interaction of DAP12 and NKp44 (Canis familiaris)


name: XPO1 binds the beta-catenin:CBY complex (Drosophila melanogaster)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP = 5-methyldeoxycytidine 5'-phosphate + 7,8-dihydrofolate


name: H(+) + H2O + lochnericine + oxidized [NADPH--hemoprotein reductase] => (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + L-ectoine + O2 <=> 5-hydroxyectoine + CO2 + succinate


name: epothilone C + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> epothilone A + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a 5-methyl-2'-deoxycytidine in DNA + ADP + 2 H(+) + phosphate + S-adenosyl-L-homocysteine => a 2'-deoxycytidine in DNA + ATP + H2O + S-adenosyl-L-methionine


name: Collagen type XIII ectodomain shedding (Xenopus tropicalis)


name: alpha-D-glucose + beta-D-fructose => H2O + sucrose


name: 2-aminoprop-2-enoate + 3-sulfanyl-1-pentanol => 3-sulfanylpentan-1-ol-L-cysteine


name: Recruitment of GRB2 to p-PTK2 (Rattus norvegicus)


name: Endocytosis (internalization) of clathrin-coated vesicle (Homo sapiens)


name: SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Dictyostelium discoideum)


name: UGT1A3 lactonizes ATV to ATVL (Mus musculus)


name: SLC34A3 cotransports Pi, 2Na+ (Canis familiaris)


name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA (Canis familiaris)


name: DEGS2 oxygenates dihydroceramide (Caenorhabditis elegans)


name: SIRPA binds SFTPA oligomer, SFTPD oligomer (Sus scrofa)


name: (R)-carnitinyl-CoA => crotonobetainyl-CoA + H2O


name: H(+) + NADH + uridine(17) in tRNA => 5,6-dihydrouridine(17) in tRNA + NAD(+)


name: MICAL1 produces NADP+, H2O2 (Sus scrofa)


name: 5-nitrosalicylate + O2 = 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H(+) + nitrite


name: AXL binds SRC-1 (Caenorhabditis elegans)


name: pelargonidin + UDP-alpha-D-glucose <=> pelargonidin 3-O-beta-D-glucoside + UDP


name: enterobactin + UDP-alpha-D-glucose = monoglucosyl-enterobactin + UDP


name: beta-D-fructose 6-phosphate <=> D-glyceraldehyde 3-phosphate + dihydroxyacetone


name: 2-(glutathione-S-yl)-hydroquinone + glutathione = glutathione disulfide + hydroquinone


name: COASY transfers an adenylyl group from ATP to PPANT (Sus scrofa)


name: dopamine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoyl-dopamine


name: Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Canis familiaris)


name: ISGylation of protein translation regulator 4EHP (Sus scrofa)


name: guanyl nucleotide exchange factor inhibitor activity


name: ATP + H(+) + nonanoate <=> diphosphate + nonanoyl-AMP


name: SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Drosophila melanogaster)


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Caenorhabditis elegans)


name: 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: (2E)-eicosenoyl-CoA + reduced [electron-transfer flavoprotein] => eicosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Plasmodium falciparum)


name: H2O2 + 2 L-ascorbate = 2 H2O + 2 monodehydro-L-ascorbate radical


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Canis familiaris)


name: ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Mus musculus)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Homo sapiens)


name: 1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol => an alkyl cinnamate + beta-D-glucose


name: USP2 binds the heterodimer of MDM2 and MDM4 (Mus musculus)


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine


name: Cytosolic CMs translocate to extracellular region (Mus musculus)


name: Direct recruitment of PI3K to p-KIT (Gallus gallus)


name: S-adenosyl-L-methionine + uridine(2634) in 25S rRNA <=> H(+) + N(3)-methyluridine(2634) in 25S rRNA + S-adenosyl-L-homocysteine


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Mus musculus)


name: 4-hydroxyphenylacetate + H(+) + NADPH + O2 = H2O + homogentisate + NADP(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 16alpha,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NEK9 binds NEK6/NEK7 in the cytosol (Canis familiaris)


name: 2 3-(4-hydroxyphenyl)pyruvate + O2 => 2 4-hydroxyphenylacetate + 2 CO2


name: HNF1B binds the HNF4A gene (Homo sapiens)


name: acetyl-CoA + holo-[ACP] => acetyl-[ACP] + CoA


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Sus scrofa)


name: Ca2+ influx through voltage gated Ca2+ channels (Rattus norvegicus)


name: ATP + N-acetyl-D-glucosamine = ADP + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate


name: ATP + N-(D-ribulosyl)-cadaverine => ADP + H(+) + N-(3-O-phospho-D-ribulosyl)-cadaverine


name: a cholesterol ester + H2O <=> a fatty acid + cholesterol + H(+)


name: 5-hexenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + hexanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Estrogen receptor binds IGF1R and SHC1 in response to estrogen (Drosophila melanogaster)


name: (R)-carnitine + 4,8-dimethylnonanoyl-CoA <=> CoA + O-4,8-dimethylnonanoyl-(R)-carnitine


name: AKR1C1 hydrogenates PREDN,PREDL (Drosophila melanogaster)


name: CRHR1,CRHR2-1 binds CRH,UCN (Gallus gallus)


name: [N-(6-aminohexanoyl)](n) + H2O = 6-aminohexanoate + [N-(6-aminohexanoyl)](n-1)


name: benzoate + glycine => H2O + N-benzoylglycine


name: 5-HT2 receptor can bind serotonin (Canis familiaris)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Xenopus tropicalis)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Xenopus tropicalis)


name: H(+)(in) + thymidine(in) <=> H(+)(out) + thymidine(out)


name: L-alanine(out) + Na(+)(out) => L-alanine(in) + Na(+)(in)


name: hyodeoxycholate + UDP-alpha-D-glucuronate = hyodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Rattus norvegicus)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Rattus norvegicus)


name: PKC-delta translocates to plasma membrane (Gallus gallus)


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H2O = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + phosphate


name: H(+) + NADPH + sepiapterin => L-threo-7,8-dihydrobiopterin + NADP(+)


name: WWP2 ubiquitinates NOTCH3 (Gallus gallus)


name: ATG10 dissociates from ATG12:ATG5 (Homo sapiens)


name: [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine => [deoxyhypusine synthase]-L-lysine + dehydrospermidine


name: dibenzofuran + H(+) + NADH + O2 => biphenyl-2,2',3-triol + NAD(+)


name: a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol(in) = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol(out)


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Mus musculus)


name: a 3'-end ribonucleotide-RNA + a 5'-end (5'-phospho)-ribonucleoside-RNA + H(+) => a ribonucleotidyl-ribonucleotide-RNA + H2O


name: Phosphorylation of STAT1 at Ser727 (Gallus gallus)


name: D-glucose + phosphate => D-glucose 6-phosphate + H2O


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Bos taurus)


name: PGM1:Mg2+ isomerises G1P to G6P (Caenorhabditis elegans)


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Gallus gallus)


name: 6-hydroxynicotinate + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin] => 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized 2[4Fe-4S]-[ferredoxin]


name: acetyl-CoA + N-terminal L-aspartyl-L-aspartyl-L-aspartyl-[protein] <=> CoA + H(+) + N-terminal N-acetyl-L-aspartyl-L-aspartyl-L-aspartyl-[protein]


name: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O => 3-maleylpyruvate + H(+)


name: 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine => L-histidine + 3 S-adenosyl-L-methionine


name: an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Caenorhabditis elegans)


name: anthranilate + 2 ATP + L-phenylalanine + S-adenosyl-L-methionine = 2 AMP + cyclopeptine + 2 diphosphate + 2 H(+) + S-adenosyl-L-homocysteine


name: Dissociation of RAS:RAF complex (Rattus norvegicus)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Mus musculus)


name: a 16alpha-hydroxysteroid + NADP(+) = a 16-oxosteroid + H(+) + NADPH


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Xenopus tropicalis)


name: glycyl-5'-AMP + holo-[peptidyl-carrier protein] => AMP + glycyl-[peptidyl-carrier protein] + H(+)


name: misfolded CFTR is degraded by the 26S proteasome (Drosophila melanogaster)


name: [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B => yaequinolone C


name: (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + 2 glutathione = (17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + glutathione disulfide + H2O


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Homo sapiens)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Bos taurus)


name: T2Rs bind bitter-tasting compounds (Gallus gallus)


name: Necl-1:Necl-2 trans heterodimer interaction (Sus scrofa)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 6beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Drosophila melanogaster)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Mus musculus)


name: 2 D-glucopyranose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate


name: sphingolipid delta-4 desaturase activity


name: Cation influx mediated by TRPC3/6/7 (Sus scrofa)


name: ATP + hexadecanoate + holo-[ACP] = AMP + diphosphate + hexadecanoyl-[ACP]


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Gallus gallus)


name: (S)-cis-N-methyltetrahydropalmatine + S-adenosyl-L-homocysteine => (S)-tetrahydropalmatine + S-adenosyl-L-methionine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Saccharomyces cerevisiae)


name: a D-glucoside + NAD(+) => a 3-dehydro-D-glucoside + H(+) + NADH


name: 3 H(+) + holo-[2-methylbutanoate polyketide synthase] + 2 malonyl-CoA + 2 NADPH + S-adenosyl-L-methionine <=> (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CO2 + 2 CoA + H2O + 2 NADP(+) + S-adenosyl-L-homocysteine


name: Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol (Homo sapiens)


name: Homer1,2,3 binds mGluR1a,5 (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + germacrene C


name: Association of Golgi  transport vesicles with microtubules (Sus scrofa)


name: Elongation of Extended Telomeric Chromosome End (Mus musculus)


name: Exocytosis of ficolin-rich granule lumen proteins (Danio rerio)


name: a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)


name: GMP + H2O => D-ribose 5-phosphate + guanine


name: GPLD1 hydrolyses GPI-anchors from proteins (Homo sapiens)


name: PNPLA4 hydrolyzes retinyl palmitate (Canis familiaris)


name: ISGylation of viral protein NS1 (Homo sapiens)


name: 4-hydroxy-N,N,N-trimethyltryptamine + ATP = ADP + aeruginascin + H(+)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Sus scrofa)


name: coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]-[ferredoxin]


name: L-lysine(out) + L-ornithine(in) => L-lysine(in) + L-ornithine(out)


name: sGC stimulators bind sGC:NO (Canis familiaris)


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Mus musculus)


name: Interleukin-5 is a homodimer (Gallus gallus)


name: Activation of TRESK (Drosophila melanogaster)


name: (R,S)-butane-2,3-diol + NAD(+) <=> (S)-acetoin + H(+) + NADH


name: alpha-D-mannose 1-phosphate + GDP-beta-L-galactose => beta-L-galactose 1-phosphate + GDP-alpha-D-mannose


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Canis familiaris)


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Bos taurus)


name: 19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Ca2+ influx into the post-synaptic cell (Caenorhabditis elegans)


name: cyclohexan-1,2-dione + H2O => 6-oxohexanoate + H(+)


name: PIAS4 SUMOylates HERC2 with SUMO1 (Gallus gallus)


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O => 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)


name: a dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] => 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a dolichyl phosphate + H(+)


name: 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate <=> 16alpha,17alpha-estriol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex  (Canis familiaris)


name: PTK2 autophosphorylates at Y397 (Homo sapiens)


name: (9Z)-tetradecenoate + ATP + CoA => (9Z)-tetradecenoyl-CoA + AMP + diphosphate


name: (3S)-hydroxytetradecanedioyl-CoA + NAD(+) = 3-oxotetradecanedioyl-CoA + H(+) + NADH


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Bos taurus)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 2beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Sus scrofa)


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Sus scrofa)


name: serine-type endopeptidase inhibitor activity


name: Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Homo sapiens)


name: UDP-alpha-D-galactose(in) + UDP-N-acetyl-alpha-D-glucosamine(out) = UDP-alpha-D-galactose(out) + UDP-N-acetyl-alpha-D-glucosamine(in)


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Sus scrofa)


name: Conjugation of SUMO1 to UBA2:SAE1 (Saccharomyces cerevisiae)


name: (9Z)-hexadecenoate + ATP + CoA = (9Z)-hexadecenoyl-CoA + AMP + diphosphate


name: Association of Cyclin A with the APC/C (Drosophila melanogaster)


name: NCOA1 binds ESR1:estrogen:TGFA gene (Canis familiaris)


name: p-Y397-PTK2 binds SRC (Caenorhabditis elegans)


name: alpha-D-ribose 1,5-bisphosphate + cytosine => CMP + phosphate


name: [DsbB protein]-dithiol + a quinone = [DsbB protein]-disulfide + a quinol


name: T-type VDCC bind T-type VDCC blockers (Sus scrofa)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Bos taurus)


name: Translocation of RIAM to plasma membrane (Xenopus tropicalis)


name: 2 Na(+)(out) + testosterone 17-sulfate(out) = 2 Na(+)(in) + testosterone 17-sulfate(in)


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Sus scrofa)


name: The distal appendage proteins recruit TTBK2 (Bos taurus)


name: 14-3-3 zeta binding allows recruitment of PI3K (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphate(in) <=> a 1,2-diacyl-sn-glycero-3-phosphate(out)


name: diphosphate + valerena-4,7(11)-diene => (2E,6E)-farnesyl diphosphate


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Rattus norvegicus)


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Bos taurus)


name: an acyl-CoA + H2O <=> a carboxylate + CoA + H(+)


name: Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Bos taurus)


name: 2 H(+) + 2 NADPH + octadecanoyl-CoA => CoA + 2 NADP(+) + octadecan-1-ol


name: p16INK4A mutants do not bind CDK4 (Homo sapiens)


name: Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) (Mus musculus)


name: A + ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] => AH2 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + serpentine


name: (6E)-8-oxolinalool + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => linalool + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: RAC1 and CDC42 activate PAK1 (Bos taurus)


name: heparan sulfate 6-O-sulfotransferase activity


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Homo sapiens)


name: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine <=> an N(6)-methyl-2'-O-methyladenosine in U2 snRNA + H(+) + S-adenosyl-L-homocysteine


name: 5,6,7,8-tetrahydromethanopterin + NAD(+) => 7,8-dihydromethanopterin + H(+) + NADH


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O


name: D-glyceraldehyde 3-phosphate + L-arginine = H(+) + N(2)-(2-carboxyethyl)-L-arginine + phosphate


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate = colnelenate + H2O


name: cis-stilbene oxide + H2O => (1R,2R)-hydrobenzoin


name: glycyl-L-methionine + H2O = glycine + L-methionine


name: KIT binds type II TKIs (Xenopus tropicalis)


name: benzene + H(+) + NADH + O2 <=> cis-1,2-dihydrobenzene-1,2-diol + NAD(+)


name: methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Dictyostelium discoideum)


name: 4-coumaroyl-CoA + H(+) + malonyl-CoA = (4-coumaroyl)acetyl-CoA + CO2 + CoA


name: Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH (Homo sapiens)


name: FLT3LG dimer:FLT3 binds FLT3 (Homo sapiens)


name: Binding of IP3 to IP3 receptor (Xenopus tropicalis)


name: CSF2RA:CSF2RB binds SFTPs (Homo sapiens)


name: ECE1 cleaves EDN1(53-90) (Canis familiaris)


name: N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: IDUA hydrolyses Heparan sulfate chain(6) (Bos taurus)


name: NUAK1 phosphorylates TP53 (Canis familiaris)


name: deaminohydroxyblasticidin S + NH4(+) => blasticidin S + H(+) + H2O


name: acetophenone + 2 ATP + H2O + hydrogencarbonate <=> 3-oxo-3-phenylpropanoate + 2 ADP + 2 H(+) + 2 phosphate


name: SLC51A:SLC51B transports bile salts from cytosol to extracellular region (Xenopus tropicalis)


name: MAF1 translocates to the nucleus (Bos taurus)


name: SREBF1 gene expression is inhibited by FOXO1 (Homo sapiens)


name: Formation of hydroxylysyl-pyridinoline cross-links (Sus scrofa)


name: daphnin + H(+) + UDP => 7,8-dihydroxycoumarin + UDP-alpha-D-glucose


name: MYSM1 deubiquitinates Histone H2A (Rattus norvegicus)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)


name: BCDX2 complex stabilizes RAD51 filament (Sus scrofa)


name: chloride(in) + Na(+)(in) => chloride(out) + Na(+)(out)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate


name: HLCS biotinylates ACACB (Rattus norvegicus)


name: H2O + neomethymycin + 2 oxidized [2Fe-2S]-[ferredoxin] => 10-deoxymethymycin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Bos taurus)


name: RUNX1 binds FOXP3 (Caenorhabditis elegans)


name: CoA + lanosteryl ester => an acyl-CoA + lanosterol


name: H2O + N-(4-aminobutyl)-3-aminopropanal + NAD(+) <=> 2 H(+) + N-(2-carboxyethyl)putrescine + NADH


name: ALAD binds to Pb2+ (Drosophila melanogaster)


name: Inactivation of Wee1 kinase (Sus scrofa)


name: acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl-Co(III)-[corrinoid Fe-S protein]


name: Na+/H+ exchanger transport (at cell membrane) (Schizosaccharomyces pombe)


name: H2O + S-succinylglutathione <=> glutathione + H(+) + succinate


name: RAC2 translocates to the ER membrane (Homo sapiens)


name: 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Mus musculus)


name: ABC7, mABC1 and mABC2 mediate heme transport (Danio rerio)


name: CO2 + phosphoethanolamine => H(+) + O-phospho-L-serine


name: argininosuccinate <=> fumarate + arginine (Schizosaccharomyces pombe)


name: (2S)-naringenin 7-O-beta-D-glucoside + H2O => (2S)-naringenin + beta-D-glucose


name: STAT5-dependent PIM1 gene expression downstream of FLT3 ITD and fusion mutants (Homo sapiens)


name: 1-hexadecanoylglycerol + H2O => glycerol + H(+) + hexadecanoate


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Xenopus tropicalis)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Xenopus tropicalis)


name: 8 AMP + bassianolide + 8 diphosphate + 8 H(+) + 4 S-adenosyl-L-homocysteine => 4 (R)-2-hydroxy-3-methylbutyrate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine


name: Defective GALT does not transfer UMP to Gal1P (Homo sapiens)


name: acetyl-CoA + spermine => CoA + H(+) + N(1)-acetylspermine


name: Opioid receptors bind opioid peptides (Gallus gallus)


name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Bos taurus)


name: HTMLYS translocates from the mitochondrial matrix to the cytosol (Homo sapiens)


name: racemase and epimerase activity, acting on amino acids and derivatives


name: Hydrolysis of PIP3 to PI(3,4)P2 (Xenopus tropicalis)


name: PREDL:ALB dissociates (Canis familiaris)


name: glutarate(out) + urate(in) <=> glutarate(in) + urate(out)


name: Self-ubiquitination of RNF41 (Drosophila melanogaster)


name: Methylthio-ribulose-P = Methylthio-ribose-P (Schizosaccharomyces pombe)


name: H2O + L-xylono-1,4-lactone = H(+) + L-xylonate


name: EGFR phosphorylates NOTCH3 (Gallus gallus)


name: Interaction of Tie2 and Grb7 (Xenopus tropicalis)


name: a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + an acyl-CoA => 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + CoA


name: SPO11 hydrolyzes DNA forming double-strand breaks (Homo sapiens)


name: KCNJ11:ABCC9 binds nicorandil (Homo sapiens)


name: GMPS dimer transforms 6TXMP to 6TGMP (Canis familiaris)


name: H2O + substance P => Gly-L-Leu-L-Met-NH2 + substance P(1-8)


name: 2-hydroxyethane-1-sulfonate(out) + Na(+)(out) => 2-hydroxyethane-1-sulfonate(in) + Na(+)(in)


name: 2-oxoglutarate + H(+) + L-glutamine + NADPH => 2 L-glutamate + NADP(+)


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Saccharomyces cerevisiae)


name: Vanin hydrolyses pantetheine to PanK, 2AET (Homo sapiens)


name: DEGS2 oxygenates dihydroceramide (Xenopus tropicalis)


name: cholesterol + 6 H(+) + 3 O2 + 6 reduced [adrenodoxin] = 4-methylpentanal + 4 H2O + 6 oxidized [adrenodoxin] + pregnenolone


name: dihydroxyacetone phosphate + L-aspartate 4-semialdehyde => 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z,12Z)-octadecadienoate + 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+)


name: hydrogencarbonate(out) + selenite(out) + Zn(2+)(out) = hydrogencarbonate(in) + selenite(in) + Zn(2+)(in)


name: hexadecanoyl-CoA + O2 <=> (2E)-hexadecenoyl-CoA + H2O2


name: ABCB1 transports PREDN,PREDL out of hepatic cells (Canis familiaris)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Drosophila melanogaster)


name: Ubiquitination of PAK-2p34 (Homo sapiens)


name: SUMOylation of NPM1 with SUMO2,3 (Gallus gallus)


name: sphing-4-enine 1-phosphate = (2E)-hexadecenal + phosphoethanolamine


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Rattus norvegicus)


name: dodecanoate + H(+) + H2O2 => dodecanal + H2O + O2


name: Formation of N-glucuronides (Bos taurus)


name: PS transports from the ER membrane to the IM membrane (Homo sapiens)


name: (R)-3-hydroxy-(13Z)-eicosenoyl-CoA => (2E,13Z)-eicosadienoyl-CoA + H2O


name: trans-Golgi Network Coat Activation (Bos taurus)


name: formate + oxalyl-CoA => formyl-CoA + oxalate


name: "ABC-type lipid A-core oligosaccharide transporter"


name: 3-deacetyl-3-vinylbacteriochlorophyllide a + ADP + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate = ATP + chlorophyllide a + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin]


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Drosophila melanogaster)


name: Active FLT3 phosphorylates CDKN1B (Bos taurus)


name: acetyl-CoA + an acyl-CoA => a 3-oxoacyl-CoA + CoA


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Gallus gallus)


name: FURIN translocates to the plasma membrane (Xenopus tropicalis)


name: 3-carboxy-2-oxobutanoate + H(+) = 2-oxobutanoate + CO2


name: Butyrylcholinesterase hydrolyzes acyl Ghrelin (Homo sapiens)


name: Degradation of Ub-SMAD7 (Caenorhabditis elegans)


name: H2O + nitrous oxide => 2 e(-) + 2 H(+) + 2 nitric oxide


name: NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Gallus gallus)


name: all-trans-4,4'-diapo-zeta-carotene + FADH2 => all-trans-4,4'-diapophytofluene + FAD + H(+)


name: AKT phosphorylates TSC2, inhibiting it (Dictyostelium discoideum)


name: H2O + N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] = H(+) + L-arginyl-[protein] + lactate


name: (2R,3S)-homoisocitrate => cis-homoaconitate + H2O


name: a carboxylate + NH4(+) => a nitrile + 2 H2O


name: USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Mus musculus)


name: an alpha-Kdo-(2->6)-lipid IVA + CMP + H(+) => a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate


name: Activation of tandem pore domain in a weak inwardly rectifying  K+ channels (Homo sapiens)


name: ATP + CoA + deoxycholate => AMP + deoxycholoyl-CoA + diphosphate


name: (9Z)-octadecenoate + CoA + H(+) => (9Z)-octadecenoyl-CoA + H2O


name: Branching and elongation of mother and daughter filaments (Dictyostelium discoideum)


name: 11-O-acetylcyathatriol + UDP-alpha-D-xylose = erinacine Q + H(+) + UDP


name: 4-hydroxyprotoasukamycin + H(+) + NADH + O2 = asukamycin + H2O + NAD(+)


name: dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine => dTDP-alpha-D-desosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: Dimerization of FGFR3 point mutants with enhanced kinase activity (Homo sapiens)


name: D-glucose + UDP-alpha-D-galactose = H(+) + lactose + UDP


name: biliverdin IXalpha + CO + Fe(2+) + H(+) + 3 H2O + 3 oxidized [NADPH--hemoprotein reductase] => heme b + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: BTG2 binds CCR4-NOT complex (Canis familiaris)


name: Acidification of Tf:TfR1 containing endosome (Dictyostelium discoideum)


name: an N(1)-methylpseudouridine in 16S/18S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyl-N(3)[(3S)-3-amino-3-carboxypropyl]pseudouridine in 16S/18S rRNA + S-methyl-5'-thioadenosine


name: Aquaporin-4 passively transports water out of cell (Bos taurus)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2 H2O = 2 (9Z)-octadecenoate + 2 H(+) + sn-glycerol 3-phosphocholine


name: PD-1 binds B7DC and B7H1 (Gallus gallus)


name: 7,8-dihydroneopterin 3'-phosphate <=> 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde phosphate


name: 2 H2O + novapikromycin + 4 oxidized [2Fe-2S]-[ferredoxin] => 4 H(+) + narbomycin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: PDE12 cleaves 2'-5' oligoadenylates  (Sus scrofa)


name: a tRNA precursor + 2 CTP => a tRNA with a 3' CC end + 2 diphosphate


name: Binding of ADAR2 homodimer to dsRNA duplex (Canis familiaris)


name: SYK binds to integrin alphaIIb beta3 (Bos taurus)


name: ERBB4s80 binds STMN1 gene (Homo sapiens)


name: CDP-choline + sphing-4-enine => CMP + H(+) + sphing-4-enine-phosphocholine


name: Carboxymycobactin binds LTF:2xFe3+:2xCO3(2-) (Homo sapiens)


name: 2,3-dihydroxybenzoate + ATP + holo-[aryl-carrier protein] <=> 2,3-dihydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate


name: (2S)-hesperetin 7-O-beta-D-glucoside + H(+) + UDP => (2S)-hesperetin + UDP-alpha-D-glucose


name: H2O + UDP-alpha-D-glucose => alpha-D-galactose 1-phosphate + 2 H(+) + UMP


name: 3-dehydro-L-gulonate + ATP <=> 3-dehydro-L-gulonate 6-phosphate + ADP + H(+)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  (Canis familiaris)


name: POLZ extends translesion synthesis (Sus scrofa)


name: butanal + hydrogen cyanide <=> (2S)-2-hydroxypentanenitrile


name: ATP + L-glutamate + L-glutamyl-[tubulin] => ADP + gamma-L-glutamyl-L-glutamyl-[tubulin] + H(+) + phosphate


name: ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O


name: H2O + L-homocysteine <=> 2-oxobutanoate + H(+) + hydrogen sulfide + NH4(+)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Bos taurus)


name: (R)-mandelamide + H2O => (R)-mandelate + NH4(+)


name: precorrin-6B + S-adenosyl-L-methionine <=> CO2 + H(+) + precorrin-7 + S-adenosyl-L-homocysteine


name: acetyl-CoA + N-terminal L-methionyl-L-glutamyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein]


name: FADH2-C4alpha-hydroperoxide + H(+) + NADPH + rifamycin SV => FADH2 + H2O + NADP(+) + rifamycin SV hemiaminal


name: 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: PC catalyzes the carboxylation of PYR to form OA (Caenorhabditis elegans)


name: butane + H(+) + NADH + O2 => butan-1-ol + H2O + NAD(+)


name: Active ARF recruits coatomer to the Golgi (Plasmodium falciparum)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Xenopus tropicalis)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Bos taurus)


name: guaethol + O2 + reduced [NADH--hemoprotein reductase] = acetaldehyde + catechol + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Homo sapiens)


name: a quinone + trans-4-hydroxy-L-proline = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)


name: lipopolysaccharide glucosyltransferase II activity


name: 14betaH-scalarane-17alpha-19-diol => (2E,6E,10E,14E)-geranylfarnesol + H2O


name: Homodimerization of VEGF proteins (Danio rerio)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Rattus norvegicus)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b (Saccharomyces cerevisiae)


name: SMO translocates to the cilium (Sus scrofa)


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Sus scrofa)


name: chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols (Sus scrofa)


name: Phosphorylation of pPTK2 by SRC (Canis familiaris)


name: 13-cis-retinol + hexadecanoyl-CoA = 13-cis-retinyl hexadecanoate + CoA


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Saccharomyces cerevisiae)


name: TRAF2:cIAP1/2 complex binds FN14:TWEAK (Canis familiaris)


name: 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine => 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-(9Z-octadecenoyl)-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: H2O + naphtopyrone YWA1 <=> acetoacetate + H(+) + naphthalene-1,3,6,8-tetrol


name: NFE2L2 dependent ATF4 expression (Homo sapiens)


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Sus scrofa)


name: [ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + a uridine in tRNA + ATP + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => [ThiI sulfur-carrier protein]-L-cysteine + a 4-thiouridine in tRNA + AMP + diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: CoA + H(+) + mycothiol => 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA


name: Interaction of other adapter proteins with p-KIT (Rattus norvegicus)


name: Dimerization of sSCF (Xenopus tropicalis)


name: AKR1B1 reduces Glc to D-sorbitol (Saccharomyces cerevisiae)


name: acetoacetyl-CoA + succinate => acetoacetate + succinyl-CoA


name: GCHFR binds to GCH1 and negatively regulates its activity (Caenorhabditis elegans)


name: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + AH2 + O2 = A + H2O + N(6)-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenosine(37) in tRNA


name: dodecapentaneoyl-[polyketide synthase] + fumagillol = holo-[polyketide synthase] + prefumagillin


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3A (GRIN3A) (Homo sapiens)


name: Phosphorylated RHOU translocates to the endosome membrane (Dictyostelium discoideum)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Homo sapiens)


name: GLI1 binds HHIP gene, PTCH2 gene and BOC gene promoters (Homo sapiens)


name: (1R,2S)-ephedrine + NAD(+) => (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Saccharomyces cerevisiae)


name: Interaction of PECAM-1 and SHP-1 (Rattus norvegicus)


name: L-homoarginine(in) + L-ornithine(out) = L-homoarginine(out) + L-ornithine(in)


name: ATP + H2O + N-11-cis-retinylidenephosphatidylethanolamine(out) <=> ADP + H(+) + N-11-cis-retinylidenephosphatidylethanolamine(in) + phosphate


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+) => a 1-O-alkyl-2-acetyl-sn-glycerol + CDP-choline


name: β3-agonists bind ADRB3 (Canis familiaris)


name: (R)-noradrenaline(out) + chloride(out) + Na(+)(out) = (R)-noradrenaline(in) + chloride(in) + Na(+)(in)


name: diphosphate + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine => CTP + H(+) + N(5)-phospho-L-glutamine


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+) => 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH


name: H2O + phosphocholine => choline + phosphate


name: 3'-phosphoadenylyl sulfate + 3beta-hydroxy-5-cholenate <=> 3beta-sulfo-5-cholenate + adenosine 3',5'-bisphosphate + H(+)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione <=> (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: a very long-chain fatty acyl-CoA + H2O => a very long-chain fatty acid + CoA + H(+)


name: SGK phosphorylates SRF (Dictyostelium discoideum)


name: p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Rattus norvegicus)


name: Formation of MSH2:MSH6 Complex (Caenorhabditis elegans)


name: H2O + octadecanamide = NH4(+) + octadecanoate


name: 2,5-hexanedione + 2 H(+) + 2 NADPH = (2R,5R)-hexanediol + 2 NADP(+)


name: AMP + H2O = adenine + D-ribose 5-phosphate


name: butanal + H2O + NAD(+) = butanoate + 2 H(+) + NADH


name: 2 Fe(II)-[cytochrome] + 2 H(+) + nitrate <=> 2 Fe(III)-[cytochrome] + H2O + nitrite


name: NADH + 2 oxidized [cytochrome P450] = H(+) + NAD(+) + 2 reduced [cytochrome P450]


name: NCOA2(869-1464) binds KAT6A(1-1118) (Gallus gallus)


name: L-ornithine + NADPH + O2 = H2O + N(5)-hydroxy-L-ornithine + NADP(+)


name: Formation of the CTF18-RFC(7s) complex (Bos taurus)


name: Activation of TAK1 complex bound to activated TLR4 complex (Rattus norvegicus)


name: Glucosylation of collagen propeptide hydroxylysines (Homo sapiens)


name: a flavonol 7-O-beta-D-glucoside + malonyl-CoA <=> a flavonol 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: a globoside DSGG (d18:1(4E)) + CMP + H(+) => a globoside MSGG (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA => (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate <=> (14S,15S)-epoxy-(5Z,8Z,10E,12E)-eicosatetraenoate + H2O


name: a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate => a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O


name: RHOU binds effectors at the plasma membrane (Xenopus tropicalis)


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Danio rerio)


name: AVPR1A,2 bind AVPR antagonists (Xenopus tropicalis)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Canis familiaris)


name: PNPLA6 hydrolyzes LysoPtdCho (Sus scrofa)


name: Removal of siRNA passenger strand (Sus scrofa)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: GRB2:SOS1 binds to HBEGF:p-Y-EGFR (Gallus gallus)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)


name: (9Z)-octadecenamide + H2O <=> (9Z)-octadecenoate + NH4(+)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Saccharomyces cerevisiae)


name: 3-methoxy-4',5-dihydroxy-trans-stilbene + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + trans-resveratrol


name: MARC1,MARC2 reduce N-hydroxylated compounds (Sus scrofa)


name: PA is converted to CDP-DAG by CDS1 (Bos taurus)


name: MECP2:SIN3A complex binds GRIA2 gene promoter (Homo sapiens)


name: 2',4,4',6'-tetrahydroxychalcone + dimethylallyl diphosphate <=> desmethylxanthohumol + diphosphate


name: Coumarin is 7-hydroxylated by CYP2A13 (Caenorhabditis elegans)


name: HDAC6 deacetylates microtubules (Mus musculus)


name: Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Caenorhabditis elegans)


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Bos taurus)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Schizosaccharomyces pombe)


name: PIAS1,3 SUMOylate NRIP1 with SUMO1 (Sus scrofa)


name: (2Z,4E)-2,3,5-trichloromuconate + H(+) => 3,4,6-trichlorocatechol + O2


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Homo sapiens)


name: (E)-caffeoyl-CoA + 5-hydroxyanthranilate <=> avenanthramide C + CoA


name: D-xylotetraono-1,5-lactone + H2O2 => D-xylotetraose + O2


name: estrone 3-sulfate(in) + H(+)(out) = estrone 3-sulfate(out) + H(+)(in)


name: Expression of HSP90B1 (Dictyostelium discoideum)


name: ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC (Canis familiaris)


name: 3 H2O + hydrogen sulfide + 3 NAD(+) <=> 4 H(+) + 3 NADH + sulfite


name: Autophosphorylation of PDGF beta receptors (Homo sapiens)


name: 2-oxoglutarate + H(+) + O2 + trihazone A => 2 CO2 + H2O + succinate + trihazone D


name: miR-25 microRNA binds PTEN mRNA (Homo sapiens)


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Saccharomyces cerevisiae)


name: phytol + tetradecanoyl-CoA = CoA + tetradecanoate phytyl ester


name: Self-ubiquitination of RNF41 (Bos taurus)


name: EGFR binds EPS15, EPN1, EPS15L1 (Homo sapiens)


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Caenorhabditis elegans)


name: Recruitment of PLC-gamma1 to LAT (Rattus norvegicus)


name: Haptoglobin-related Protein binds Hemoglobin (Sus scrofa)


name: ATXN3 deubiquitinates polyUb-PARK2 (Mus musculus)


name: B4GALT5/6 transfer Gal to GlcCer (Canis familiaris)


name: alpha-maltoheptaose + beta-D-glucose => alpha-maltohexaose + beta-maltose


name: Importin-8 imports AGO2:miRNA into the nucleus (Rattus norvegicus)


name: NCOA1 recruits EP300 to the ABCA1 promoter (Drosophila melanogaster)


name: SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Homo sapiens)


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Danio rerio)


name: D-xylono-1,5-lactone + H(+) + NADPH => D-xylose + NADP(+)


name: Spermidine  => N-acetylated spermidine (Xenopus tropicalis)


name: glycerol + H(+) + sn-glycerol 3-phosphate => H2O + sn-glycero-3-phospho-(1'-sn-glycerol)


name: Nuclear VBC complex ubiquitinylates HIF-alpha (Mus musculus)


name: H(+) + oxidized [electron-transfer flavoprotein] + pentanoyl-CoA <=> (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]


name: NEUROG3-dependent synthesis of INSM1 (Homo sapiens)


name: CYLD deubiquitinates NEMO (Homo sapiens)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Caenorhabditis elegans)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Drosophila melanogaster)


name: 5alpha-cholesta-7,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 7-dehydrodesmosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: L-histidine <=> NH4(+) + trans-urocanate


name: ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Rattus norvegicus)


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Plasmodium falciparum)


name: L-quinate + NADP(+) => 3-dehydroquinate + H(+) + NADPH


name: 1-hexanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+)


name: (20S)-ginsenoside Rh2 + D-glucose => (20S)-ginsenoside Rg3 + H2O


name: 5-HT2 receptor can bind serotonin (Mus musculus)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Dictyostelium discoideum)


name: GDP-6-deoxy-alpha-D-altrose + sordaricin => 4'-O-demethylsordarin + GDP + H(+)


name: MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Rattus norvegicus)


name: Disintegration of matrix layer (Homo sapiens)


name: Follistatin (FST) binds Activin (Drosophila melanogaster)


name: bisdemethoxycurcumin + 2 CO2 + 3 CoA => 2 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Caenorhabditis elegans)


name: A + cannabigerolate = AH2 + cannabichromenate


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Gallus gallus)


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Gallus gallus)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Mus musculus)


name: HMBL spontaneously transforms to URO1 (Homo sapiens)


name: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 <=> 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)


name: CYP4F3 20-hydroxylates LTB4 (Rattus norvegicus)


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Caenorhabditis elegans)


name: ATP + holo-[peptidyl-carrier protein] + L-alanine <=> AMP + diphosphate + L-alanyl-[peptidyl-carrier protein]


name: (E)-caffeoyl-CoA + quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = CoA + H(+) + quercetin 3-O-[(6-O-[(E)-caffeoyl]-beta-D-glucosyl)-(1->2)-beta-D-glucoside]


name: MYLK (MLCK) Active Calmodulin Binding (Canis familiaris)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycerol + UDP-alpha-D-galactose


name: GPIHBP1 binds HSPG:LPL dimer (Rattus norvegicus)


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Xenopus tropicalis)


name: (13S,14R)-1,13-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase]


name: SARS-CoV-2 M protein binds MAP1LC3B (Homo sapiens)


name: RYK binds WNT5A and VANGL2 (Homo sapiens)


name: ARL3:GTP binds the UNC119B complex (Danio rerio)


name: SLC2A9 transports Fru, Glc, urate (Homo sapiens)


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Bos taurus)


name: FMO2:FAD:Mg2+ S-oxidises MTZ (Rattus norvegicus)


name: Mitochondrial BTD hydrolyses BCTN (Bos taurus)


name: Formation of Cyclin A:Cdk2 complexes (Gallus gallus)


name: PRC1 SUMOylates CTBP1 with SUMO2,3 (Homo sapiens)


name: alpha-NAD(+) + H2O <=> ADP-D-ribose + H(+) + nicotinamide


name: H(+) + imidazole-4-acetate + NADH + O2 <=> 5-hydroxyimidazole-4-acetate + H2O + NAD(+)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate


name: acetyl-CoA + N-terminal L-methionyl-L-isoleucyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein]


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Xenopus tropicalis)


name: asperterpenoid A + 5 H(+) + 5 H2O + 4 oxidized [NADPH--hemoprotein reductase] => 4 O2 + preasperterpenoid A + 4 reduced [NADPH--hemoprotein reductase]


name: acetyl-CoA + ADP + oxaloacetate + phosphate = ATP + citrate + CoA


name: Parkin promotes the ubiquitination of mitochondrial substrates (Homo sapiens)


name: CO + H(+) + N-acetylanthranilate => 3-hydroxy-2-methyl-1H-quinolin-4-one + O2


name: [eIF5A protein]-L-lysine + spermidine <=> [eIF5A protein]-deoxyhypusine + propane-1,3-diamine


name: 2 GTP + H(+) = diphosphate + P(1),P(4)-bis(5'-guanosyl) tetraphosphate


name: GOT2 dimer deaminates L-Asp (Danio rerio)


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Canis familiaris)


name: Disassociation and translocation of STATs to the nucleus (Sus scrofa)


name: NSF ATPase activity dissociates cis-SNARE (Rattus norvegicus)


name: 2 (E)-4-coumaroyl-CoA + spermidine => 2 CoA + 2 H(+) + N(1),N(8)-bis(coumaroyl)-spermidine


name: mRNA N1-methyladenosine dioxygenase activity


name: cyclo(L-tryptophyl-L-alanyl) + dimethylallyl diphosphate => diphosphate + preechinulin


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Canis familiaris)


name: CSF3 dimer:CSFR:LYN:JAK1 binds CSFR:LYN:JAK1 (Gallus gallus)


name: ZNRF3 autoubiquitinates to promote its internalization (Sus scrofa)


name: Histone acetyltransferases are recruited to the TFF1 gene (Saccharomyces cerevisiae)


name: FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis (Homo sapiens)


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Sus scrofa)


name: acetoin + H(+) + NADPH + NH4(+) => 3-aminobutan-2-ol + H2O + NADP(+)


name: 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = ADP-D-ribose + H(+) + L-glutamyl-[protein]


name: CoA + N(6)-acetyl-N(6)-hydroxy-L-lysine => acetyl-CoA + N(6)-hydroxy-L-lysine


name: Phosphorylation of c-Abl and Arg by ATM (Gallus gallus)


name: IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)


name: PECAM1 is phosphorylated (Rattus norvegicus)


name: RHOD:GTP translocates to the endosome membrane (Danio rerio)


name: 2 sucrose = 6-kestotriose + beta-D-glucose


name: ATF2 acetylates histone H2B, H4 (Homo sapiens)


name: D-cysteine(out) + L-alanine(in) <=> D-cysteine(in) + L-alanine(out)


name: cysteamine S-phosphate + H2O <=> cysteamine + phosphate


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Drosophila melanogaster)


name: p-S407,Y641-STAT6 is dimerized (Rattus norvegicus)


name: 4 H2O + O2 + 4 sulfur <=> 6 H(+) + 2 hydrogen sulfide + 2 sulfite


name: Degradation multiubiquitinated Cyclin A (Canis familiaris)


name: a dihydroceramide + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a phytoceramide + 2 Fe(III)-[cytochrome b5] + H2O


name: hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 (Xenopus tropicalis)


name: Activated PCLG1 dissociates from NTRK3 (Canis familiaris)


name: GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Drosophila melanogaster)


name: Recruitment of PLC-gamma1 to LAT (Mus musculus)


name: H2O + N(2)-[(2E)-3-methylhex-2-enoyl]-L-glutaminate => (2E)-3-methylhex-2-enoate + L-glutamine


name: (9Z)-hexadecenoyl-[ACP] + NAD(+) => (2E,9Z)-hexadecadienoyl-[ACP] + H(+) + NADH


name: SREBP1A,1C binds the FASN promoter (Homo sapiens)


name: 5alpha-androstan-3,17-dione + H(+) + NADH => 17beta-hydroxy-5alpha-androstan-3-one + NAD(+)


name: 1/3-PP-IP5 transports from the cytosol to the nucleus (Homo sapiens)


name: AKT1 binds eNOS complex via HSP90 (Dictyostelium discoideum)


name: 2-oxoglutaramate + H2O = 2-oxoglutarate + NH4(+)


name: aurachin C epoxide + H2O + NADP(+) => aurachin C + H(+) + NADPH + O2


name: (11Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(13Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]


name: PC catalyzes the carboxylation of PYR to form OA (Schizosaccharomyces pombe)


name: (9Z,11E)-octadecadienoate + H2O => 10-hydroxy-(11E)-octadecenoate


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)


name: hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate => phosphate + S-methyl-5'-thioinosine


name: aspartic acid methylthiotransferase activity


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Bos taurus)


name: iodide transmembrane transporter activity


name: TP53 family members bind the TP53I3 (PIG3) gene promoter (Homo sapiens)


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Sus scrofa)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(in) + ATP + H2O <=> ADP + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(out) + H(+) + phosphate


name: (2E,6E)-farnesyl diphosphate + H2O => (3S,6E)-nerolidol + diphosphate


name: 4-coumaroyl-CoA + shikimate = CoA + trans-4-coumaroylshikimate


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Canis familiaris)


name: (3S)-hydroxyhexanoyl-CoA = (2E)-hexenoyl-CoA + H2O


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + glycerol + H(+) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O


name: POMC(138-176) binds MC2R (Canis familiaris)


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Xenopus tropicalis)


name: (3R)-3-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylate + 2-oxoglutarate + O2 <=> (3R)-[(10S)-11-epoxyfarnesyl]-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate + CO2 + succinate


name: 2 ATP + 2 cob(II)inamide + 2 H2O + reduced [electron-transfer flavoprotein] <=> 2 adenosylcob(III)inamide + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate


name: EP300 acetylates histone H2A, H2B, H3, H4 (Sus scrofa)


name: (3R)-hydroxyoctacosanoyl-CoA + NADP(+) => 3-oxooctacosanyol-CoA + H(+) + NADPH


name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Xenopus tropicalis)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-tetradecanoyl-sn-glycerol 3-phosphate + choline + H(+)


name: GPI dimer isomerizes Fru(6)P to G6P (Bos taurus)


name: 3,4-dihydroxybenzoate + bromide + 2 H(+) + NADPH + O2 => 3-bromo-4,5-dihydroxybenzoate + 2 H2O + NADP(+)


name: a 2'-deoxycytidine in double-stranded DNA + CO2 + glyoxal + succinate => 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + H2O + O2


name: ent-cassa-12,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = ent-3beta-hydroxycassa-12,15-dien-2-one + 3 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: The acetyl group from acetyl-CoA is transferred to the NAT1 (Mus musculus)


name: DDX5 binds ESR1:estrogen:TFF1 gene promoter (Homo sapiens)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Gallus gallus)


name: Defective CYP1B1 does not 4-hydroxylate EST17b (Homo sapiens)


name: 3-demethylubiquinol-10 + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + ubiquinol-10


name: (8Z,11Z,14Z)-eicosatrienoate + 2 O2 => prostaglandin G1


name: carnitine + NAD(+) <=> 3-dehydrocarnitine + H(+) + NADH


name: 2-oxoglutarate + 4-amino-L-phenylalanine <=> 3-(4-aminophenyl)pyruvate + L-glutamate


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Xenopus tropicalis)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)


name: vascular endothelial growth factor receptor 2 binding


name: IGF2BP3 binds specific RNAs (Homo sapiens)


name: Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Homo sapiens)


name: TMEM55B translocates to the nucleus (Canis familiaris)


name: AMP + glutathione disulfide + 2 H(+) + sulfite <=> adenosine 5'-phosphosulfate + 2 glutathione


name: 6'-chloromelleolide F + FAD + H(+) + 2 H2O => chloride + FADH2 + melleolide F + O2


name: SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol = a 1,2-diacylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: 2-oxoglutarate + L-isoleucine <=> (S)-3-methyl-2-oxopentanoate + L-glutamate


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexanoyl-sn-glycero-3-phosphocholine => 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Gallus gallus)


name: amidinoproclavaminate + CO2 + succinate => 2-oxoglutarate + deoxyamidinoproclavaminate + O2


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Bos taurus)


name: 9-ribosyl-trans-zeatin 5'-phosphate + H2O + NADP(+) => H(+) + N(6)-(dimethylallyl)adenosine 5'-phosphate + NADPH + O2


name: glycyl-tRNA(Ala) + H2O <=> glycine + H(+) + tRNA(Ala)


name: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH


name: Transfer of SUMO2 from E1 to UBE2I (UBC9) (Homo sapiens)


name: Follistatin (FST) binds Activin (Homo sapiens)


name: AVPR2 bind desmopressin (Xenopus tropicalis)


name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Rattus norvegicus)


name: acetyl-CoA + anthranilate <=> CoA + N-acetylanthranilate


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Sus scrofa)


name: MAPK1 phsophorylates ZC3HCF1 in a NPM-ALK-dependent manner (Homo sapiens)


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate => diphosphate + ent-13-epi-manoyl oxide


name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Rattus norvegicus)


name: β3-agonists bind ADRB3 (Rattus norvegicus)


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Rattus norvegicus)


name: 1,6-dihydro-beta-NADP + H(+) + O2 <=> H2O2 + NADP(+)


name: P4HB mediates disulfide bond formation in Proinsulin (Rattus norvegicus)


name: (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate => (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2


name: H(+) + menaquinone-8 + NADH => menaquinol-8 + NAD(+)


name: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + 3 diphosphate


name: "hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]"


name: diphosphate + discoidol => (2E,6E)-farnesyl diphosphate + H2O


name: Autocatalytic phosphorylation of FGFR4 Y367C mutant (Homo sapiens)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Sus scrofa)


name: (9Z)-hexadecenamide + H2O = (9Z)-hexadecenoate + NH4(+)


name: Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B (Canis familiaris)


name: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glycine betaine + 2 H(+) + NADPH => betaine aldehyde + H2O + NADP(+)


name: [eIF5A protein]-deoxyhypusine + propane-1,3-diamine => [eIF5A protein]-L-lysine + spermidine


name: 1D-myo-inositol 1,4,5-trisphosphate + 2 ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 2 ADP + 2 H(+)


name: Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Danio rerio)


name: adenosine 5'-phosphosulfate + NH4(+) <=> adenosine 5'-phosphoramidate + 2 H(+) + sulfate


name: H(+)(out) + L-asparagine(in) = H(+)(in) + L-asparagine(out)


name: H2O + O2 + spermine => H2O2 + NH4(+) + spermine monoaldehyde


name: 2-oxoglutarate + hexadecanoyl-CoA + O2 <=> 2-hydroxyhexadecanoyl-CoA + CO2 + succinate


name: TPMT transfers CH3 from AdoMet to 6MP (Danio rerio)


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: 7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid (Rattus norvegicus)


name: HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Mus musculus)


name: Furin cleaves pro-factor VII to factor VII (Mus musculus)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Dictyostelium discoideum)


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Bos taurus)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Saccharomyces cerevisiae)


name: (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity


name: Dynamin is recruited to the gap junction plaque (Rattus norvegicus)


name: ATP + D-ribose 5-phosphate <=> 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)


name: prephenate + S-adenosyl-L-methionine => 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Danio rerio)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Rattus norvegicus)


name: Autophosphorylation of PKC-theta (Homo sapiens)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Sus scrofa)


name: 2 glutathione + L-cystine = glutathione disulfide + 2 L-cysteine


name: D-arabinose 5-phosphate + H2O + phosphoenolpyruvate <=> 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate


name: Phosphorylation of LIMK-1 by PAK (Rattus norvegicus)


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Danio rerio)


name: SMURF1/2 dissociates from ub-PTCH1 (Drosophila melanogaster)


name: A + beta-dihydromenaquinone-9 => AH2 + menaquinone-9


name: an N-(1,2 saturated very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(III)-[cytochrome b5] + H2O


name: P2Y6 receptor can bind to UDP (Mus musculus)


name: TBC1D3 associates with RAB5 (Drosophila melanogaster)


name: PEX7 binds cargo proteins containing PTS2 (Danio rerio)


name: chloride(out) + L-tryptophan(out) + 2 Na(+)(out) => chloride(in) + L-tryptophan(in) + 2 Na(+)(in)


name: Nck binds to the active PDGF receptor (Rattus norvegicus)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Sus scrofa)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Mus musculus)


name: (2E,6E,10E)-geranylgeraniol + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: 2,4,6-trichlorophenol + FADH2 + O2 = 2,6-dichlorobenzoquinone + chloride + FAD + H(+) + H2O


name: (2E,6E)-hedycaryol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha-yl acetate


name: 10-hydroxy-(11E)-octadecenoate => (9E,11E)-octadecadienoate + H2O


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)


name: 9'-cis-neoxanthin + O2 = (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al + 2-cis,4-trans-xanthoxin


name: Release of novel PDGFs as latent factors (Caenorhabditis elegans)


name: P2RX4,7 binds itself to form trimeric non-selective cation channels (Homo sapiens)


name: an N-acylneuraminate 9-phosphate + H2O => an N-acylneuraminate + phosphate


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho]-glycerol + CoA


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Sus scrofa)


name: (3R)-hydroxytetradecanoyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine => holo-[ACP] + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine


name: RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Mus musculus)


name: E2F6 binds TFDP1 (Dictyostelium discoideum)


name: BTK in active Gq-BTK complex is activated (Gallus gallus)


name: FN1 binds Collagen types I-V, VII (Xenopus tropicalis)


name: Binding of IP3 to IP3 receptor (Dictyostelium discoideum)


name: high-affinity potassium ion transmembrane transporter activity


name: CCNK binds CDK13 (Drosophila melanogaster)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Schizosaccharomyces pombe)


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Caenorhabditis elegans)


name: p-STAT1 binds p-STAT3 (Rattus norvegicus)


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Gallus gallus)


name: [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate + H2O <=> [amino-group carrier protein]-C-terminal-L-glutamate + L-ornithine


name: BTN3A1 and BTN1A1 binds periplakin (PPL) (Homo sapiens)