name: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 => (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Gallus gallus)


name: 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+) => 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH


name: 2-hydroxymethyl-3-pentylphenol + O2 + reduced [NADPH--hemoprotein reductase] => (8S)-annullatin E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Homo sapiens)


name: ZnT5 transports zinc into the golgi apparatus (Bos taurus)


name: Association of Golgi  transport vesicles with microtubules (Canis familiaris)


name: 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecenyl)-glycerol


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: TBK1, IKBKE phosphorylate RIPK1 at T189 (Sus scrofa)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Schizosaccharomyces pombe)


name: 1-(10Z-heptadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine


name: RHOD binds effectors at the Golgi membrane (Caenorhabditis elegans)


name: RAC1,RAC2,RHOG activate PI3K (Gallus gallus)


name: voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels


name: 7-cyano-7-carbaguanosine(15) in tRNA + H2O + L-glutamine <=> archaeosine(15) in tRNA + L-glutamate


name: SLC29A1 transports RBV from cytosol to extracellular region (Dictyostelium discoideum)


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Drosophila melanogaster)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Mus musculus)


name: H(+) + hydrogencarbonate + NADH + propanoyl-CoA => (S)-2-methyl-3-oxopropanoate + CoA + H2O + NAD(+)


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Caenorhabditis elegans)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Drosophila melanogaster)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Danio rerio)


name: P4HB binds Collagen chains (Drosophila melanogaster)


name: ATP + L-aspartate = 4-phospho-L-aspartate + ADP


name: (9Z,12Z,15Z)-octadecatrien-1-ol + 1-hexadecanoylglycerone 3-phosphate = 1-O-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate + H(+) + hexadecanoate


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Xenopus tropicalis)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Rattus norvegicus)


name: GSDMD oligomerizes into arc-, slit-shaped structures (Rattus norvegicus)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Homo sapiens)


name: glycine(out) + L-alanine(in) = glycine(in) + L-alanine(out)


name: TPX2 binds AURKA at centrosomes (Canis familiaris)


name: p-T,Y MAPK dimers translocate to nucleus (Rattus norvegicus)


name: SFTPB binds itself (Dictyostelium discoideum)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Dictyostelium discoideum)


name: a 1-[(9Z,12Z,15Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: p-Y693-STAT4 dissociates after IL12:IL12R interaction (Bos taurus)


name: 5alpha-androstane-3alpha,17beta-diol + NAD(+) <=> 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADH


name: 4-oxo-4-(pyridin-3-yl)butanal + 2 Fe(II)-[cytochrome c] + 2 H(+) + methylamine => 2 Fe(III)-[cytochrome c] + H2O + pseudooxynicotine


name: Orexin 2 receptor can bind orexin-B neuropeptide (Danio rerio)


name: beta-catenin is replaced by repression complexes at the promoter (Drosophila melanogaster)


name: CBL dissociates from ubiquitinated p-SPRY2 (Canis familiaris)


name: indole + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase]


name: 2-demethylmenaquinol-10 + S-adenosyl-L-methionine = H(+) + menaquinol-10 + S-adenosyl-L-homocysteine


name: acetylcholine + CoA => acetyl-CoA + choline


name: transcription termination site sequence-specific DNA binding


name: BTK in G alpha (12)-BTK complex is activated (Homo sapiens)


name: UVSSA:USP7 deubiquitinates ERCC6 (Mus musculus)


name: ISGylation of E2 conjugating enzymes (Sus scrofa)


name: L-histidyl-[protein] + NAD(+) = H(+) + N(tele)-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide


name: (3R)-hydroxybutanoate dimer + (R)-3-hydroxybutanoate + H(+) => (3R)-hydroxybutanoate trimer + H2O


name: RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Mus musculus)


name: 6-hydroxynicotinate + 2 H(+) + NADH + O2 => 2,5-dihydroxypyridine + CO2 + H2O + NAD(+)


name: a long-chain fatty acyl-AMP + holo-[ACP] = a long-chain fatty acyl-[ACP] + AMP + H(+)


name: alpha-D-ribose 1,5-bisphosphate + AMP + H(+) => ADP + alpha-D-ribose 1-phosphate


name: Caspase-mediated cleavage of Z0-2 (Drosophila melanogaster)


name: SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Rattus norvegicus)


name: ATP + docosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] = AMP + diphosphate + docosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Caenorhabditis elegans)


name: RASA1 stimulates RAS GTPase activity (Drosophila melanogaster)


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate <=> CO2 + deoxyviolacein + 2 H2O + NAD(+)


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine <=> 3,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine


name: H(+) + isopentadecanoyl-CoA + malonyl-CoA => 3-oxoisoheptadecanoyl-CoA + CO2 + CoA


name: 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+) => 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol + ATP


name: 2-methylmaleate + H2O => (2R,3S)-3-methylmalate


name: formate + H(+) + L-kynurenine => H2O + N-formyl-L-kynurenine


name: 3 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) => 3 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+)


name: L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide


name: ATP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine = ADP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H(+) + phosphate


name: BRAF and RAF fusion mutant dimers are phosphorylated (Homo sapiens)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O


name: Histone H3.3 deposition at telomere (Bos taurus)


name: 2'-deoxyuridine + 2-oxoglutarate + O2 => 2-deoxy-D-ribono-1,4-lactone + CO2 + succinate + uracil


name: calcidiol + UDP-alpha-D-glucuronate = calcidiol 3-O-(beta-D-glucuronide) + H(+) + UDP


name: Association of Nek2A with MCC:APC/C (Mus musculus)


name: GTP loading by Rheb (Dictyostelium discoideum)


name: 2-oxoglutarate + a quinol => (S)-2-hydroxyglutarate + a quinone


name: Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX (Dictyostelium discoideum)


name: (E)-coniferol + NADP(+) => (E)-coniferaldehyde + H(+) + NADPH


name: A + AMP + diphosphate + ilicicolin B => AH2 + ATP + ilicicolinate B


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Canis familiaris)


name: AKT can phosphorylate NR4A1 (NUR77) (Homo sapiens)


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Xenopus tropicalis)


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] <=> akuammicine + formate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Exocyst complex formation (Homo sapiens)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Danio rerio)


name: H(+) + N(omega)-alpha-(ADP-D-ribosyl)-L-arginyl-[dinitrogen reductase] + nicotinamide => L-arginyl-[dinitrogen reductase] + NAD(+)


name: GAL3ST1 transfers sulfate to GalCer,LacCer (Sus scrofa)


name: (6R)-5,10-methenyltetrahydrofolate + H2O + N(1)-(5-phospho-beta-D-ribosyl)glycinamide => (6S)-5,6,7,8-tetrahydrofolate + 2 H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Canis familiaris)


name: Duplex siRNA is loaded into Argonaute (Mus musculus)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Canis familiaris)


name: HMGB1 release from cells (Schizosaccharomyces pombe)


name: (S)-ureidoglycolate <=> glyoxylate + urea


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Danio rerio)


name: Exocytosis of specific granule membrane proteins (Sus scrofa)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Homo sapiens)


name: PRLR associates with JAK2 (Homo sapiens)


name: NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Homo sapiens)


name: Abortive Initiation Before Second Transition (Bos taurus)


name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Danio rerio)


name: a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate <=> a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate


name: anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity


name: SMAD7:NEDD4L complex translocates to the cytosol (Homo sapiens)


name: PKA phosphorylates MAPKAPK5 (Mus musculus)


name: 2 L-tyrosyl-tRNA(Tyr) => cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)


name: deacetylipecoside + H2O = dopamine + secologanin


name: TFAP2C homodimer binds MYC and KDM5B (Mus musculus)


name: IGFBP1 binds IGF forming IGF:IGFBP1 (Bos taurus)


name: 3-oxododecanoate + H(+) <=> 2-undecanone + CO2


name: CO + H(+) + N-octanoylanthranilate => 2-heptyl-3-hydroxy-4(1H)-quinolone + O2


name: MRN complex bound to DNA ends recruits ATM (Homo sapiens)


name: H2O + S-(ADP-D-ribosyl)-L-cysteinyl-[protein] => ADP-D-ribose + L-cysteinyl-[protein]


name: 3-guanidinopropanoate + L-ornithine => beta-alanine + L-arginine


name: acetoacetate + coenzyme M + NADP(+) => 2-oxopropyl-coenzyme M + CO2 + NADPH


name: HEXB cleaves the terminal GalNAc from small HA fragments (Bos taurus)


name: Exocytosis of specific granule lumen proteins (Danio rerio)


name: RDX binds to and ubiquitinates CI (Drosophila melanogaster)


name: Some pathogenic BRCA1 mutants do not bind BARD1 (Homo sapiens)


name: (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O => (9Z-octadecenoyl)-glycerol + phosphate


name: PARG dePARylates PARP1,PARP2 (Mus musculus)


name: GPI dimer isomerizes Fru(6)P to G6P (Xenopus tropicalis)


name: PAK1-3 phosphorylates VE-cadherin (Rattus norvegicus)


name: hexan-1-ol + hexanoyl-CoA = CoA + hexyl hexanoate


name: PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Saccharomyces cerevisiae)


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) <=> 3-hydroxy-3-methyl-2-oxobutanoate + H(+) + NADPH


name: Type B histone acetlytransferase complex acetylates histone H4 (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: RUNX1:CBFB binds EP300 (Canis familiaris)


name: H2O + methylamine + NAD(+) = formaldehyde + H(+) + NADH + NH4(+)


name: 2-oxoglutarate + 3-methylhexadecanoyl-CoA + O2 = 2-hydroxy-3-methylhexadecanoyl-CoA + CO2 + succinate


name: GDIs block activation of RHOG (Dictyostelium discoideum)


name: GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol (Xenopus tropicalis)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> a fatty acid + H(+) + sn-glycero-3-phosphoethanolamine


name: (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + NADPH <=> (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + NADP(+)


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Schizosaccharomyces pombe)


name: 2-dehydro-D-gluconate + ATP <=> 6-phospho-2-dehydro-D-gluconate + ADP + H(+)


name: H(+)(out) + L-alanyl-L-glutamate(out) => H(+)(in) + L-alanyl-L-glutamate(in)


name: (R)-lactate + 2 Fe(III)-[cytochrome c] => 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: Cis-homodimerization of nectins (Homo sapiens)


name: 2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] => 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: Activation of voltage gated Potassium channels (Rattus norvegicus)


name: acarbose + ATP <=> acarbose 7(IV)-phosphate + ADP + H(+)


name: CHRM1,3,5 bind acetylcholine (Sus scrofa)


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Mus musculus)


name: 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate => (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil


name: O2 + 4 tellimagrandin II <=> 2 cornusiin E + 2 H2O


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Bos taurus)


name: Translocation of WWTR1 (TAZ) to the nucleus (Caenorhabditis elegans)


name: RAC1 and CDC42 activate PAK2 (Danio rerio)


name: 2-acyl LPE is acylated to PE by LPEAT (Xenopus tropicalis)


name: SUMOylation of Histone H4 with SUMO1 (Gallus gallus)


name: (R)-2-hydroxyglutarate + NADP(+) <=> 2-oxoglutarate + H(+) + NADPH


name: 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine => 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate


name: sialic acid transmembrane transporter activity


name: 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + ATP + CoA = 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA + AMP + diphosphate


name: (2Z,6Z)-farnesyl diphosphate => beta-acoradiene + diphosphate


name: A + dTDP-beta-L-evernitrose + H2O => AH2 + dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + O2


name: BTG2 binds CCR4-NOT complex (Gallus gallus)


name: Formation of the 43S pre-initiation complex (Sus scrofa)


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Bos taurus)


name: glycolate(in) + H(+)(in) <=> glycolate(out) + H(+)(out)


name: 1-hydroxy-2-butanone + H2O + NAD(+) => butan-2-one + H(+) + NADH + O2


name: L-arginine(in) + L-histidine(out) + Na(+)(out) <=> L-arginine(out) + L-histidine(in) + Na(+)(in)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Drosophila melanogaster)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Gallus gallus)


name: (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose => glucoerucin + H2O


name: ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE (Sus scrofa)


name: ATG7:ATG3:LC3 dissociates (Mus musculus)


name: Autophosphorylation of KIT (Xenopus tropicalis)


name: Recruitment of CstF to the CPSF Bound Pre-mRNA (Rattus norvegicus)


name: 2 (S)-lactate(out) + thromboxane B2(in) => 2 (S)-lactate(in) + thromboxane B2(out)


name: trans-Golgi Network Coat Activation (Plasmodium falciparum)


name: MIR132 gene expression is stimulated by p-S133-CREB1 (Homo sapiens)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Saccharomyces cerevisiae)


name: PLK1 phosphorylates BORA (Gallus gallus)


name: Initial activation of proMMP3 (Canis familiaris)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out)


name: acetate + L-glutamate 5-semialdehyde => H2O + N-acetyl-L-glutamate 5-semialdehyde


name: [L-4-(L-arginin-2-N-yl)aspartate](n) + H2O => [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate


name: dIMP + H2O = 2-deoxy-D-ribose 5-phosphate + hypoxanthine


name: (8Z,11Z)-eicosadienoyl-CoA + A + 2 H2O => (11Z)-eicosenoyl-CoA + AH2 + O2


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Drosophila melanogaster)


name: (9Z)-octadecenoate + 9-hydroxy-octadecanoate + H(+) => 9-(9Z-octadecenoyloxy)-octadecanoate + H2O


name: AKT phosphorylates KAT6A (Schizosaccharomyces pombe)


name: Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) (Homo sapiens)


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Gallus gallus)


name: Dimerized phospho-IRF3 migrates to the nucleus (Canis familiaris)


name: beta-catenin is replaced by repression complexes at the promoter (Sus scrofa)


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Canis familiaris)


name: 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Caenorhabditis elegans)


name: The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Gallus gallus)


name: 2-all-trans-decaprenylphenol + H(+) + NADPH + O2 => 3-(all-trans-decaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: 2-nitroimidazole + H2O = 1,3-dihydro-2H-imidazol-2-one + H(+) + nitrite


name: ATP + L-cysteine + L-glutamate => ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate


name: H2O + N(2)-benzoyl-D-arginine-4-nitroanilide = 4-nitroaniline + H(+) + N(2)-benzoyl-D-arginine


name: Methylthio-ribulose-P = Methylthio-ribose-P (Mus musculus)


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Canis familiaris)


name: MVD decarboxylates MVA5PP to IPPP (Dictyostelium discoideum)


name: 3-oxooctadecanoyl-CoA + CoA => acetyl-CoA + hexadecanoyl-CoA


name: RFC binding displaces Pol Alpha (Drosophila melanogaster)


name: MHC class II antigen processing (Plasmodium falciparum)


name: Loading of dopamine into synaptic veiscles (Caenorhabditis elegans)


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)


name: H(+) + H2O + isoguanine = NH4(+) + xanthine


name: 1,17beta-dihydroxyandrostan-3-one => Delta(1)-dihydrotestosterone + H2O


name: CoA-disulfide + H2O => 4'-phosphopantetheinyl-CoA disulfide + adenosine 3',5'-bisphosphate + 2 H(+)


name: p-EFNB binds GRB4 (Caenorhabditis elegans)


name: 9-cis-10'-apo-beta-carotenal + 2 O2 = (11R)-carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Xenopus tropicalis)


name: HIPK2 phosphorylates RUNX1 (Drosophila melanogaster)


name: KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Homo sapiens)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Mus musculus)


name: Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 (Homo sapiens)


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Bos taurus)


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Mus musculus)


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Rattus norvegicus)


name: CFTR F508del binds CFTR correctors (Homo sapiens)


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)


name: 7-deoxyloganate + H(+) + UDP => 7-deoxyloganetate + UDP-alpha-D-glucose


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycerol 3-phosphate = 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: 2-oxoglutarate + O-phospho-L-serine => 3-phosphooxypyruvate + L-glutamate


name: NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: D-galactono-1,4-lactone + H2O => D-galactonate + H(+)


name: emodin + S-adenosyl-L-methionine = physcion + S-adenosyl-L-homocysteine


name: ABC-type amino acid transporter activity


name: CREB3L2 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Homo sapiens)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Rattus norvegicus)


name: (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] = (R)-mandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1,2-dihexadecanoyl-sn-glycerol + H(+) + phosphocholine


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Canis familiaris)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Homo sapiens)


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Saccharomyces cerevisiae)


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + a ribonucleoside 5'-triphosphate => a 5'-end NTP-ribonucleotide-RNA + AMP + H(+)


name: a glycerophospholipid(in) + ATP + H2O => a glycerophospholipid(out) + ADP + H(+) + phosphate


name: Formation of VAF (virus-activated factor) complex (Rattus norvegicus)


name: RHOA GEFs activate RHOA (Rattus norvegicus)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate => ectocarpin C


name: Alkalization of the phagosomal lumen by NOX2 (Homo sapiens)


name: 2 A + echinenone + 3 H2O => 2 AH2 + all-trans-beta-carotene + 2 O2


name: SFKs phosphorylates RAF1 on Y340,Y341 (Caenorhabditis elegans)


name: PIP3 recruits AKT to the membrane (Dictyostelium discoideum)


name: 2 Fe(II)-[cytochrome c3] + thiosulfate => 2 Fe(III)-[cytochrome c3] + hydrogen sulfide + sulfite


name: Soluble TNF-α binds TNFR1 (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Gallus gallus)


name: CYP26A1,B1 4-hydroxylate atRA (Homo sapiens)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Homo sapiens)


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Drosophila melanogaster)


name: L-rhamnofuranose + NAD(+) = H(+) + L-rhamnono-1,4-lactone + NADH


name: PAOX:FAD oxidises NASPN to SPM (Canis familiaris)


name: alpha-D-glucose 1-phosphate + ATP + H(+) <=> ADP-alpha-D-glucose + diphosphate


name: GTP + L-glutamate + oxidized coenzyme F420-(gamma-L-Glu)(n) => GDP + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n+1) + phosphate


name: (9Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Xenopus tropicalis)


name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA (Drosophila melanogaster)


name: 4-hydroxyphenylacetate + FADH2 + O2 => 3,4-dihydroxyphenylacetate + FAD + H(+) + H2O


name: (2E,6E)-farnesyl diphosphate => (+)-alpha-barbatene + diphosphate


name: Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. (Caenorhabditis elegans)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Dictyostelium discoideum)


name: 3-dehydro-4-methylzymosterol + CO2 + NADH => 4beta-methylzymosterol-4alpha-carboxylate + NAD(+)


name: 2-(dihydroxymethyl)-5-formylfuran => 2,5-diformylfuran + H2O


name: beta-alanyl-L-ornithine + H2O => beta-alanine + L-ornithine


name: HSD17B13 binds lipid droplets (Drosophila melanogaster)


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Canis familiaris)


name: Formation of a heteromeric BMP receptor complex (Sus scrofa)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Sus scrofa)


name: 3-alpha-D-mannopyranosyl-alpha-D-mannopyranose + UDP-alpha-D-xylose = 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose + H(+) + UMP


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Sus scrofa)


name: pteridine-2,4,6,7-tetrol = H(+) + xanthine-8-carboxylate


name: 1-deoxysphinganine + a fatty acyl-CoA = CoA + H(+) + N-acyl-1-deoxysphinganine


name: Formation of NR-MED1 Coactivator Complex (Sus scrofa)


name: (2E,4E)-decadienoyl-CoA + H(+) + NADPH <=> (3E)-decenoyl-CoA + NADP(+)


name: docosanoyl-CoA + H2O = CoA + docosanoate + H(+)


name: SLC6A4 binds TCAs and SSRIs (Rattus norvegicus)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Gallus gallus)


name: aspartic endopeptidase activity, intramembrane cleaving


name: Activation of Ca permeable AMPA receptors (Canis familiaris)


name: D-maltoheptaono-1,5-lactone + H2O = D-maltoheptaonate + H(+)


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Dictyostelium discoideum)


name: 3'-phosphoadenylyl sulfate + estrone 3-O-(beta-D-glucuronate) <=> adenosine 3',5'-bisphosphate + estrone 3-O-(3-sulfo-beta-D-glucuronate) + H(+)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Canis familiaris)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] <=> 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH


name: Translocation of Vav1 to CD28 (Xenopus tropicalis)


name: SUMOylation of TFAP2C with SUMO1 (Bos taurus)


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Schizosaccharomyces pombe)


name: p-MAPK2/3 phosphorylates HSP27 (Caenorhabditis elegans)


name: IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Mus musculus)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Xenopus tropicalis)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Rattus norvegicus)


name: TTYH1 transports cytosolic Cl- to extracellular region (Sus scrofa)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: isoepoxydon + NADP(+) => H(+) + NADPH + phyllostine


name: 3-hydroxy-L-kynurenine + glyoxylate = 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + glycine


name: (2E,6E)-farnesyl diphosphate + S-adenosyl-L-methionine => H(+) + pre-sodorifen diphosphate + S-adenosyl-L-homocysteine


name: a menaquinone + 2 H(+)(in) + H2 <=> a menaquinol + 2 H(+)(out)


name: ROS oxidize thioredoxin (Canis familiaris)


name: uroporphyrinogen III => coproporphyrinogen III + 4 CO2 (Gallus gallus)


name: a 5'-end (5'-phospho)-ribonucleoside-RNA + S-adenosyl-L-methionine <=> a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] = 1,5-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N(6)-malonyl-L-lysyl-[protein] + NAD(+) = 2''-O-malonyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: A + H2O + quinolin-6-ol => 6-hydroxyquinolin-2(1H)-one + AH2


name: Retrograde COPI vesicles bind kinesin and microtubules (Sus scrofa)


name: Formation of hydroxylysyl-pyrrole cross-links (Danio rerio)


name: SYK autophosphorylates at the activated BCR (Bos taurus)


name: 1'-[1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol


name: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnose + H2O <=> 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Canis familiaris)


name: p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Mus musculus)


name: (E)-3-(indol-3-yl)acryloyl-CoA + H2O => (R)-3-(indol-3-yl)lactoyl-CoA


name: SCF:FBXL7 binds AURKA (Rattus norvegicus)


name: DARPP-32 is dephosphorylated on Thr75 by PP2A (Canis familiaris)


name: L-seryl-[protein] + pentanoyl-CoA = CoA + O-pentanoyl-L-seryl-[protein]


name: L-proline + NADP(+) => 1-pyrroline-5-carboxylate + 2 H(+) + NADPH


name: 1-acyl LPG is acylated to PG by LPGAT (Caenorhabditis elegans)


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Canis familiaris)


name: Group 3 - Selective Cl- transport (Saccharomyces cerevisiae)


name: dihydrorhizobitoxine + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + rhizobitoxine


name: (Z)-3-ureidoacrylate + H2O <=> (Z)-3-aminoacrylate + carbamate + H(+)


name: NAD(P)+ transhydrogenase (AB-specific) activity


name: MigFilin associates with Filamin and F-actin (Sus scrofa)


name: a 5'-end triphospho-guanosine-ribonucleotide-snRNA + S-adenosyl-L-methionine <=> a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + S-adenosyl-L-homocysteine


name: 7-deoxyloganetate + UDP-alpha-D-glucose => 7-deoxyloganate + H(+) + UDP


name: [thioredoxin]-disulfide + prostamide F2alpha => [thioredoxin]-dithiol + prostamide H2


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Homo sapiens)


name: a globoside GalGb3Cer + H(+) + UDP => a globoside Gb3Cer + UDP-alpha-D-galactose


name: Ca impermeable AMPA receptor ligand binding (Drosophila melanogaster)


name: 2 ATP + 2 cob(II)alamin + 2 H2O + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate


name: Recruitment of SYK to p-DAP12 (Mus musculus)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Sus scrofa)


name: USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Sus scrofa)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Mus musculus)


name: H(+) + oleanolate 3-O-beta-D-glucoside + UDP => oleanolate + UDP-alpha-D-glucose


name: citrate(out) + tartrate(in) => citrate(in) + tartrate(out)


name: (4R)-4-hydroxy-2-oxoglutarate <=> glyoxylate + pyruvate


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Sus scrofa)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Canis familiaris)


name: beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructose 2-phosphate + phosphate


name: (9Z,12Z)-octadecadienoate + O2 => (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate


name: 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine => 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + S-adenosyl-L-methionine


name: adenosine in rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine in rRNA + S-adenosyl-L-homocysteine


name: (Z)-3-hydroxypropyl glucosinolate + H2O <=> (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + NADP(+)


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 5'-deoxyadenosine + 8-methyladenosine(2503) in 23S rRNA + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: (3S)-hydroxytetradecanoyl-CoA => (2E)-tetradecenoyl-CoA + H2O


name: p-S115 MAPKAPK5 translocates to the cytosol (Mus musculus)


name: a triacylglycerol + an acyl-3-O-(beta-D-galactosyl)-sn-glycerol => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol


name: ATP + Co(2+) + H2O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 5 H(+) + phosphate


name: (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one <=> (3R)-3-isopropenyl-6-oxoheptanoate + H(+)


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Caenorhabditis elegans)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Bos taurus)


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Bos taurus)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)


name: ADP(in) + dATP(out) <=> ADP(out) + dATP(in)


name: Phosphorylation of nephrin by FYN (Sus scrofa)


name: cyclic dehypoxanthinylfutalosinate = 1,4-dihydroxy-6-naphthoate + chemical entity


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Danio rerio)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H(+)


name: H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate => acetylsalicylate + L-lysyl-[protein]


name: Interaction of PECAM-1 and SHP-1 (Gallus gallus)


name: H2O + 2 NADP(+) + tetracenomycin C => 2 H(+) + 2 NADPH + 2 O2 + tetracenomycin A2


name: griseofulvin + NADP(+) => dehydrogriseofulvin + H(+) + NADPH


name: PTP-RO interacts with p-c-Kit complex (Bos taurus)


name: 2 H(+)(out) + nitrite(out) + 3 ubiquinol-8(in) => 2 H2O(out) + NH4(+)(out) + 3 ubiquinone-8(in)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: CDC42:GTP recruits DIAPH2-2 to kinetochores (Homo sapiens)


name: ISGylation of E2 conjugating enzymes (Drosophila melanogaster)


name: L-tryptophan => 2-aminoprop-2-enoate + indole


name: 3,3'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine => 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine


name: Tyrosine is monoiodinated (Drosophila melanogaster)


name: alpha-D-mannose 1-phosphate + GDP + H(+) => GDP-alpha-D-mannose + phosphate


name: CHRM2 binds CHRM2 antagonists (Canis familiaris)


name: 2-demethylmenaquinone-8 + H2O + trimethylamine => 2-demethylmenaquinol-8 + H(+) + trimethylamine N-oxide


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Sus scrofa)


name: Formation of CDK4/6:CCND complexes (Drosophila melanogaster)


name: LIPT2 transfers octanoyl group to GCSH (Caenorhabditis elegans)


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Sus scrofa)


name: 2 O2 + ubiquinol-8 => 2 H(+) + 2 superoxide + ubiquinone-8


name: [thioredoxin]-disulfide + dUDP + H2O => [thioredoxin]-dithiol + UDP


name: H(+) + O-carbamoyl-L-serine = 2-aminoprop-2-enoate + CO2 + NH4(+)


name: NTRK3 dimers trans-autophosphorylate (Rattus norvegicus)


name: Phosphorylation of STAT1 by JAK kinases (Canis familiaris)


name: PGE2 is converted to PGF2a by CBR1 (Xenopus tropicalis)


name: Active FLT3 phosphorylates CDKN1B (Sus scrofa)


name: (9E)-octadecenoyl-CoA + FAD + H(+) = (2E,9E)-octadecadienoyl-CoA + FADH2


name: (3R)-3-hydroxy-L-arginyl-[ribosomal protein eS6] + CO2 + succinate => 2-oxoglutarate + L-arginyl-[ribosomal protein eS6] + O2


name: Receptor ACKR2 binds most inflammatory CC chemokines (Homo sapiens)


name: LIPC dimer binds heparin (Gallus gallus)


name: Translocation of Cdc25 to the nucleus (Drosophila melanogaster)


name: H(+) + N-acetyl-S-(2-succino)-L-cysteine + NADH + O2 => H2O + N-acetyl-L-cysteine + NAD(+) + oxaloacetate


name: H(+) + methyl isocyanate + viridicatin => (-)-cyclopenine


name: (2E,15Z)-tetracosadienoyl-CoA + H2O => (3R)-hydroxy-(15Z)-tetracosenoyl-CoA


name: TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Xenopus tropicalis)


name: ATP + carbamoyl phosphate + H2O + kanamycin A => 6''-O-carbamoylkanamycin A + AMP + diphosphate + H(+) + phosphate


name: PSMD14 cleaves K63-linked ubiquitin (Caenorhabditis elegans)


name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)


name: a ubiquinone + H(+) + Na(+)(in) + NADH <=> a ubiquinol + Na(+)(out) + NAD(+)


name: NGF binding to p75NTR inactivates RHOA (Homo sapiens)


name: a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GD1b (d18:1(4E)) + H(+) + UDP


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Bos taurus)


name: Hydrolysis of phosphatidylcholine (Canis familiaris)


name: 2-oxoglutarate + an N(1)-ethyl-2'-deoxyadenosine in single-stranded DNA + O2 = a 2'-deoxyadenosine in single-stranded DNA + acetaldehyde + CO2 + H(+) + succinate


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: picrinine + S-adenosyl-L-methionine <=> ervincine + H(+) + S-adenosyl-L-homocysteine


name: diphthine-[translation elongation factor 2] + H(+) + S-adenosyl-L-homocysteine => 2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine


name: 2-ethylhexyl sulfate + 2-oxoglutarate + O2 => 2-ethylhexanal + CO2 + H(+) + succinate + sulfate


name: a carboxylate + ATP + H(+) = an acyl-AMP + diphosphate


name: 4-aminophenol + CO2 + H2O + NADP(+) => 4-aminobenzoate + 2 H(+) + NADPH + O2


name: a cytidine in 26S rRNA + S-adenosyl-L-methionine => a 5-methylcytidine in 26S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine => 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O


name: p-Y-STATs translocate to nucleus (Dictyostelium discoideum)


name: ABC-type ferric-enterobactin transporter activity


name: CBL binds and ubiquitinates phosphorylated Sprouty (Drosophila melanogaster)


name: H2O + N-octadecanoylsphing-4-enine => octadecanoate + sphing-4-enine


name: AUF1 (hnRNP D0) is ubiquitinylated (Dictyostelium discoideum)


name: chloride + chlorohydroquinone + glutathione disulfide + H(+) => 2,5-dichlorohydroquinone + 2 glutathione


name: glutarate(in) + prostaglandin E2(out) <=> glutarate(out) + prostaglandin E2(in)


name: 5,6-dihydrothymine + NAD(+) <=> H(+) + NADH + thymine


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Danio rerio)


name: H(+) + NADH + NH4(+) + octanal => H2O + NAD(+) + octylamine


name: PHB and all-E-10PrP2 are combined into DHB by COQ2 (Sus scrofa)


name: glyoxylate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine


name: Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Caenorhabditis elegans)


name: ROS oxidize thioredoxin (Drosophila melanogaster)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Sus scrofa)


name: HDAC3 containing complexes deacetylate histone (Bos taurus)


name: cytidine(49) in tRNA(Asp) + S-adenosyl-L-methionine => 5-methylcytidine(49) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: Autocatalytic activation of MMP1 (Bos taurus)


name: protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity


name: H2O + hexacosanoyl-CoA = CoA + H(+) + hexacosanoate


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Rattus norvegicus)


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Homo sapiens)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Plasmodium falciparum)


name: a flavonol 3-O-beta-D-glucoside + UDP-beta-L-rhamnose <=> a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + H(+) + UDP


name: HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Xenopus tropicalis)


name: TP53I3 oxidoreductase generates unstable semiquinones (Xenopus tropicalis)


name: 2-oxoglutarate + a flavanone + O2 => a flavone + CO2 + H2O + succinate


name: PIAS4 SUMOylates PARP1 with SUMO1 (Homo sapiens)


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Sus scrofa)


name: HMIT co-transports myo-inositol with a proton (Caenorhabditis elegans)


name: (8Z,11Z)-5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine <=> (8Z,11Z)-5-(pentadeca- 8,11,14-trien-1-yl)resorcinol-3-methyl ether + H(+) + S-adenosyl-L-homocysteine


name: Activated FGFR1 binds FRS2 (Mus musculus)


name: PIAS1,2-1 SUMOylates AR with SUMO1 (Gallus gallus)


name: Alkalization of the phagosomal lumen by NOX2 (Rattus norvegicus)


name: P2Y10 receptor can bind to LPA (Bos taurus)


name: NH4(+) + oxaloacetate => (3R)-3-hydroxy-D-aspartate


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: TBC1D25 (OATL1) binds ATG8 homologues (Bos taurus)


name: Caspase-mediated cleavage of occludin (Sus scrofa)


name: alpha,alpha-trehalose + phosphate <=> beta-D-glucose 1-phosphate + D-glucose


name: SGSH hydrolyses Heparan sulfate chain(7) (Canis familiaris)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Xenopus tropicalis)


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Bos taurus)


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Mus musculus)


name: Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Bos taurus)


name: Dephosphorylation of AKT by PP2A (Caenorhabditis elegans)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3  phosphorylates STAT1,STAT3 (Danio rerio)


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)


name: H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate


name: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> an (11Z)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Sus scrofa)


name: FAM20C phosphorylates FAM20C substrates (Mus musculus)


name: "Thioether and trialkylsulfonium hydrolases"


name: NTPDase3 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: (S)-reticuline + O2 <=> (S)-scoulerine + H(+) + H2O2


name: 4-hydroxy-5-methyl-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA => 2 H(+) + malonyl-CoA + methylmalonyl-CoA + octadecanoyl-CoA


name: glutarate-semialdehyde dehydrogenase (NADP+) activity


name: ent-copalyl diphosphate = diphosphate + ent-isokaurene


name: Phosphorylation of LAT by p-SYK (Sus scrofa)


name: DENND6A,B exchange GTP for GDP on RAB14 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + longifolene


name: a 2-acyl-4,6-diprenylphloroglucinol + dimethylallyl diphosphate <=> a 2-acyl-4,6,6-triprenylphloroglucinol + diphosphate


name: Phosphorylation of PKC theta (Sus scrofa)


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + dimethylallyl diphosphate = (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + diphosphate


name: D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH


name: MKRN1 polyubiquitinates PTEN (Xenopus tropicalis)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate => (S)-3-methyl-2-oxopentanoate + H2O


name: N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: PPM1L dephosphorylates multiphospho-CERT1-2 (Homo sapiens)


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Rattus norvegicus)


name: Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 (Mus musculus)


name: pro-SFTPB translocates from ER membrane to multivesicle body (Drosophila melanogaster)


name: CPO transforms COPRO3 to PPGEN9 (Schizosaccharomyces pombe)


name: pre-VLDL binds lipids to form VLDL (Sus scrofa)


name: (6Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoyl-CoA + O2


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Homo sapiens)


name: SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Homo sapiens)


name: GM-CSF receptor alpha:GM-CSF binds Bc (Homo sapiens)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Sus scrofa)


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: 2 dimethylallyl diphosphate = (R)-lavandulyl diphosphate + diphosphate


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Gallus gallus)


name: (9Z)-octadecenoate + 1-octadecanoyl-2-hydroxy-sn-glycero-3-phospho-(N-hexadecanoyl)-serine + H(+) => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(N-hexadecanoyl)-serine + H2O


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Canis familiaris)


name: CHIT1 hydrolyses CHIT to 3xADGP (Mus musculus)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Xenopus tropicalis)


name: Phosphorylated ERBB2 TMD/JMD heterodimers bind SHC1 (Homo sapiens)


name: a fatty acid + H(+) + long chain acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol => H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)


name: H(+) + H2O2 + L-ascorbate => L-gulono-1,4-lactone + O2


name: NTPDase3 hydrolyzes nucleoside triphosphates (Mus musculus)


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Sus scrofa)


name: TBK1 phosphorylates STAT6 at Ser407 (Sus scrofa)


name: SGTA binds Tail-anchored protein (Gallus gallus)


name: p-PKR dimer phosphorylates PTPN2 (Homo sapiens)


name: MSH2:MSH6 exchanges ADP for ATP (Rattus norvegicus)


name: anthraniloyl-CoA + methanol <=> CoA + O-methyl anthranilate


name: SFTPAs translocate from ER membrane to extracellular region (Danio rerio)


name: DEGS1 dehydrogenates dihydroceramide (Caenorhabditis elegans)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Canis familiaris)


name: demethylphylloquinone + H(+) + NADPH = demethylphylloquinol + NADP(+)


name: L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose => a neolactoside III(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: MRN bound to shortened telomeres activates ATM (Canis familiaris)


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Mus musculus)


name: ATP(out) + 2 H(+)(out) + phosphate(in) = ATP(in) + 2 H(+)(in) + phosphate(out)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Bos taurus)


name: Autophosphorylation of PAK1,2,3 (Danio rerio)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Canis familiaris)


name: fluoroacetyl-CoA + H2O => CoA + fluoroacetate + H(+)


name: H2O + N(omega)-methyl-L-arginine => L-citrulline + methylamine


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + GDP-beta-L-fucose = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc derivative + GDP + H(+)


name: carbohydrate transmembrane transporter activity


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O


name: lactose + N-acetylneuraminate => H2O + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose


name: HOXC8 binds CDH11 gene promoter (Homo sapiens)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP => di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine


name: SH2 domain of Src binds to the active receptor (Mus musculus)


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Dictyostelium discoideum)


name: P2Y10 receptor can bind to LPA (Canis familiaris)


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Mus musculus)


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 1-O-methyl-12-hydroperoxy-20-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: PELI1 binds activated RIPK1:RIPK3 (Bos taurus)


name: carbonyl sulfide + H2O = CO2 + H(+) + hydrogen sulfide


name: Complex of NOTCH1 with its ligand is cleaved to produce NEXT1 (Homo sapiens)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Drosophila melanogaster)


name: N-hydroxy-L-tetrahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-tetrahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Formation of MSH2:MSH6 Complex (Dictyostelium discoideum)


name: botB LC cleaves target cell VAMP2 (Homo sapiens)


name: UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Dictyostelium discoideum)


name: D-glucose(out) + H(+)(out) = D-glucose(in) + H(+)(in)


name: alanine transmembrane transporter activity


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Rattus norvegicus)


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Canis familiaris)


name: rhamnetin + S-adenosyl-L-methionine => 7,4'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine


name: translation regulator activity, nucleic acid binding


name: EFCAB7:IQCE binds EVC2:EVC (Homo sapiens)


name: dec-9-enoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = dec-9-ynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: adenosine 3',5'-bisphosphate(out) + FMN(in) => adenosine 3',5'-bisphosphate(in) + FMN(out)


name: 3-methyl-2-butenal + adenine + AH2 => A + H2O + N(6)-dimethylallyladenine


name: 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + CO2 + CoA => (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + H(+) + malonyl-CoA


name: Addition of galactose to Core 6 glycoprotein (Xenopus tropicalis)


name: Activated FGFR1 phosphorylates SHC1 (Drosophila melanogaster)


name: (3S)-versiconol acetate + NADP(+) <=> (2S,3S)-versiconal hemiacetal acetate + H(+) + NADPH


name: [thioredoxin]-dithiol + NADP(+) <=> [thioredoxin]-disulfide + H(+) + NADPH


name: dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] <=> CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: biphenyl-2-ol + H(+) + sulfite => 2'-hydroxybiphenyl-2-sulfinate + H2O


name: DPP4 binds DPP4 inhibitors (Mus musculus)


name: HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 (Sus scrofa)


name: aldehydo-D-apiose + H(+) + NADH => D-apiitol + NAD(+)


name: L-Glutamine transport into neurons (Xenopus tropicalis)


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate = (1S,8aR)-delta-cadinene + diphosphate


name: 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol


name: A + a D-alpha-amino acid + H2O <=> a 2-oxocarboxylate + AH2 + NH4(+)


name: PPM1L dephosphorylates multiphospho-CERT1-2 (Danio rerio)


name: a 5'-end phospho-ribonucleoside in mRNA + FAD + H(+) => a 5'-end FAD-phospho-ribonucleoside in mRNA + H2O


name: 7-deoxyloganetic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-cis-trans-nepetalactol + O2 + reduced [NADPH--hemoprotein reductase]


name: MMACHC dealkylates RCbl (Dictyostelium discoideum)


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Saccharomyces cerevisiae)


name: carnosine(out) + 2 H(+)(out) = carnosine(in) + 2 H(+)(in)


name: H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol = a fatty acid + H(+) + long chain 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: CYP3A7 can 6beta-hydroxylate testosterone (Bos taurus)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Rattus norvegicus)


name: a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione = a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Xenopus tropicalis)


name: (2E)-eicosenoyl-CoA + H(+) + NADH => eicosanoyl-CoA + NAD(+)


name: 3-hydroxyanthranilate + O2 => (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde


name: GOPC promotes translocation of CFTR to lysosomes (Mus musculus)


name: [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B <=> yaequinolone C


name: RHOT2 binds effectors at the mitochondrial outer membrane (Schizosaccharomyces pombe)


name: D-dopachrome + H(+) <=> 5,6-dihydroxyindole + CO2


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Xenopus tropicalis)


name: Activated ESR1 binds the RUNX2 gene promoter (Homo sapiens)


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Mus musculus)


name: 8 H(+) + malonamoyl-[OxyC ACP] + 8 malonyl-CoA <=> 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA


name: (2S)-naringenin + S-adenosyl-L-methionine => (2S)-sakuranetin + H(+) + S-adenosyl-L-homocysteine


name: H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide => a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Dictyostelium discoideum)


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Drosophila melanogaster)


name: 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + H2O + phosphoenolpyruvate = phosphate + pseudaminate


name: H(+) + NADH + scyllo-inosine => 1D-chiro-inositol + NAD(+)


name: Methylation of N-acetyl-5-HT to form melatonin (Canis familiaris)


name: 1-O-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + glutarate + H(+)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Homo sapiens)


name: H2O + plasmodiophorol B = plasmodiophorol C


name: S1PR1 binds S1PR1 agonists (Mus musculus)


name: a 5'-end triphospho-adenosine in mRNA + H2O => a 5'-end diphospho-adenosine in mRNA + H(+) + phosphate


name: Disassembly of tight junctions (Homo sapiens)


name: SLC9B1/C2 exchange Na+ for H+ (Gallus gallus)


name: (1S,4R)-menthone + H(+) + NADPH + O2 = (4S,7R)-7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+)


name: CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus (Caenorhabditis elegans)


name: ATP + H2O + vincristine(in) <=> ADP + H(+) + phosphate + vincristine(out)


name: ATP + CoA + heptanedioate <=> 6-carboxyhexanoyl-CoA + AMP + diphosphate


name: NCOA1 recruits EP300 to TGFA promoter (Mus musculus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Bos taurus)


name: TFAP2C homodimer binds MYC and KDM5B (Danio rerio)


name: AH2 + S-(methylsulfanyl)glutathione => A + glutathione + methanethiol


name: PKA/PKG phosphorylate Rap1GAP2 (Sus scrofa)


name: C5 binds C5 inhibitors (Rattus norvegicus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Homo sapiens)


name: Association of HMGB1/HMGB2 with chromatin (Danio rerio)


name: SLC6A15-mediated amino acid uptake (Drosophila melanogaster)


name: Factor D cleaves C3(H2O)-bound Factor B (Mus musculus)


name: H(+) + L-prolyl-[peptidyl-carrier protein] + 2 oxidized [electron-transfer flavoprotein] => (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 reduced [electron-transfer flavoprotein]


name: FKBP1A binds tacrolimus (Drosophila melanogaster)


name: acetyl-CoA + chloramphenicol = chloramphenicol 3-acetate + CoA


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O => 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+)


name: PDGF-BB clevage by Furin (Canis familiaris)


name: Interaction of integrin alphaDbeta2 with fibrin (Rattus norvegicus)


name: BRISC complex deubiquitinates NLRP3 (Rattus norvegicus)


name: Activated FGFR1 binds FRS3 (Xenopus tropicalis)


name: 3 ATP + H2O + L-2-aminoadipate + L-cysteine + L-valine = 3 AMP + 3 diphosphate + 3 H(+) + N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine


name: Na+/H+ exchanger transport (at cell membrane) (Canis familiaris)


name: arginine + glycine => ornithine + guanidoacetate (Homo sapiens)


name: Aminoacyl-tRNA  binds to the ribosome at the A-site (Homo sapiens)


name: PDGF-BB clevage by Furin (Gallus gallus)


name: L-tyrosyl-L-isoleucyl-L-leucine + neurotensin(1-10) => H2O + neurotensin


name: Formation of the SET1A complex (Schizosaccharomyces pombe)


name: Parkin binds Ub:UBE2N:UBE2V1 (Canis familiaris)


name: 2-oxo-3-sulfanylpropanoate + L-cysteinyl-[protein] <=> pyruvate + S-sulfanyl-L-cysteinyl-[protein]


name: octadecanoyl-CoA + sphing-4-enine = CoA + H(+) + N-octadecanoylsphing-4-enine


name: apigenin 7-O-beta-D-glucoside + malonyl-CoA = apigenin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: Formation of hair keratin fibres (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine <=> H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine


name: (2E,6E)-farnesyl diphosphate = alpha-humulene + diphosphate


name: (25S)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (25S)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Defective KHK does not phosphorylate beta-D-fructose (Homo sapiens)


name: DAG is acylated to TAG by DGAT1/2 (Canis familiaris)


name: Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Homo sapiens)


name: PSMD14 cleaves K63-linked ubiquitin (Mus musculus)


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Danio rerio)


name: 5'-deoxyadenosine + A + H(+) + L-methionine + neomycin B => AH2 + neomycin C + S-adenosyl-L-methionine


name: H2O + N(6)-(D-psicosyl)-L-lysyl-[protein] => D-allose + L-lysyl-[protein]


name: CoA + H(+) + N-acetyl-L-glutamate 5-semialdehyde => acetyl-CoA + L-glutamate 5-semialdehyde


name: p-5Y-RET complexes bind GRB2 (Drosophila melanogaster)


name: NPAS4 represses INS gene expression (Homo sapiens)


name: WLS dissociates from retromer (Bos taurus)


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Rattus norvegicus)


name: (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase] => 4-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-2-hydroxypropyl-coenzyme M => (S)-1,2-epoxypropane + coenzyme M


name: Cargo-carrying vesicles bud from the TGN (Rattus norvegicus)


name: VTN binds collagens II, III and V (Mus musculus)


name: beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphoenolpyruvate => 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphate


name: 2 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)


name: 1-octadecanoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoserine + 9,10-epoxyoctadecanoate + H(+)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Sus scrofa)


name: CBR3 reduces DOX to DOXOL (Canis familiaris)


name: Activation of Rap1 by cytosolic GEFs (Sus scrofa)


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Schizosaccharomyces pombe)


name: 3-(4-hydroxyphenyl)pyruvate + O2 = (S)-4-hydroxymandelate + CO2


name: p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN (Gallus gallus)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Mus musculus)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Schizosaccharomyces pombe)


name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex (Xenopus tropicalis)


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Mus musculus)


name: Autophosphorylation of PAK1 (Canis familiaris)


name: NADP(+) + prostaglandin F2alpha = H(+) + NADPH + prostaglandin E2


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)


name: MSRA reduces L-methyl-(S)-S-oxide to L-Methionine (Bos taurus)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Dictyostelium discoideum)


name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA (Sus scrofa)


name: (S)-malate(out) + succinate(in) => (S)-malate(in) + succinate(out)


name: H2O + lanosteryl hexadecanoate <=> H(+) + hexadecanoate + lanosterol


name: 9-cis-retinyl hexadecanoate + CoA => 9-cis-retinol + hexadecanoyl-CoA


name: ATP + N-acetyl-D-glucosamine = ADP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: 23S rRNA (adenosine(1067)-2'-O)-methyltransferase activity


name: 7alpha-hydroxy-3-oxochol-24-oyl-CoA + H(+) + NADH => chenodeoxycholoyl-CoA + NAD(+)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Bos taurus)


name: O2 + preaspterpenacid acid I + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + preaspterpenacid acid II


name: SPRY2 translocates to the plasma membrane (Homo sapiens)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Rattus norvegicus)


name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression (Sus scrofa)


name: Parkin transfers Ub to misfolded proteins (Sus scrofa)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Dictyostelium discoideum)


name: formate + GTP + H(+) => CO2 + dGTP + H2O


name: (R)-lactate + H(+) + sulfate => (R)-2-O-sulfolactate + H2O


name: Formation of the MLL4 complex (Bos taurus)


name: p75NTR:NADE promotes caspase2/3 activation (Bos taurus)


name: PLEKHA3,8 bind PI4P, ARF1 (Saccharomyces cerevisiae)


name: Association of procollagen type XXII (Homo sapiens)


name: ATF4 and CEBPB,CEBPG bind the ASNS gene (Homo sapiens)


name: Re-integration of insulin receptor into plasma membrane (Xenopus tropicalis)


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: (-)-alpha-cuprenene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) => 3,7-dideoxy-D-threo-hepto-2,6-diuolosonate + H(+) + NADH + NH4(+)


name: phycocyanobilin-L-cysteinyl(155)-[phycoerythrocyanin beta-subunit] => (2R,3E)-phycocyanobilin + apo-L-cysteinyl(155)-[phycoerythrocyanin beta-subunit]


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine => 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: p-T,Y MAPKs dimerize (Dictyostelium discoideum)


name: hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Drosophila melanogaster)


name: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate


name: 5'-dehydroadenosine + H2O + O2 = 9-riburonosyladenine + H(+) + H2O2


name: (22S)-22-hydroxysitosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + sitosterol


name: CYP19A1 hydroxylates ANDST to E1 (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate <=> 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Mus musculus)


name: (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O <=> (3R,6R)-6-hydroxy-3-isopropenylheptanoate + H(+)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Drosophila melanogaster)


name: 3-(hydrohydroxyphosphoryl)pyruvate + acetyl-CoA + H2O <=> CoA + H(+) + phosphinomethylmalate


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Canis familiaris)


name: SENP1,2,5 proteolytically process SUMO2 (Xenopus tropicalis)


name: 2-methylpropan-1-amine + H2O + NAD(+) => 2-methylpropanal + H(+) + NADH + NH4(+)


name: GTP loading by Rheb (Drosophila melanogaster)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)


name: ATP + CoA + deoxycholate = AMP + deoxycholoyl-CoA + diphosphate


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate => ATP + L-seryl-[protein]


name: 3'-AMP(in) + ADP(out) + H(+)(out) = 3'-AMP(out) + ADP(in) + H(+)(in)


name: L-xylo-hex-3-ulonolactone => H(+) + L-ascorbate


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Gallus gallus)


name: 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate (Gallus gallus)


name: 2 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) = 2 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Bos taurus)


name: (1R,2R)-12-hydroxyjasmonate + H2O + NADP(+) => H(+) + jasmonate + NADPH + O2


name: SAR1 Activation And Membrane Binding (Danio rerio)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Canis familiaris)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Danio rerio)


name: factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain (Gallus gallus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate


name: VKORC1 inhibitors binds VKORC1 dimer (Drosophila melanogaster)


name: 2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] <=> 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: SERPINA6 binds PREDN (Xenopus tropicalis)


name: NAD(+) + S-(2-aminoethyl)-L-cysteine => (4S)-5,6-dihydro-4H-1,3-thiazine-4-carboxylate + 2 H(+) + NADH + NH4(+)


name: BIL dissociates from GSTA1, FABP1 (Caenorhabditis elegans)


name: (3R)-1,4-thiomorpholine-3-carboxylate + NAD(+) = 3,4-dehydrothiomorpholine-3-carboxylate + 2 H(+) + NADH


name: (R)-carnitine + ATP + CoA <=> (R)-carnitinyl-CoA + AMP + diphosphate


name: Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + H2O <=> (10S)-hydroxy-(12Z)-octadecenoate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base => a 1,2-diacyl-sn-glycerol + an inositol phosphomannosylnositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: 1-O-alkyl-sn-glycero-3-phosphate + H2O => 1-O-alkyl-sn-glycerol + phosphate


name: GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol (Caenorhabditis elegans)


name: [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose + GDP-alpha-D-mannose = alpha-D-mannosyl-(1->4)-[3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose + GDP + H(+)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Saccharomyces cerevisiae)


name: VDR agonists bind VDR (Drosophila melanogaster)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Homo sapiens)


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Drosophila melanogaster)


name: Formation of BRCA1-A complex at DNA DSBs (Sus scrofa)


name: a ganglioside GT2 (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GT1c (d18:1(4E)) + H(+) + UDP


name: MSRA reduces L-methyl-(S)-S-oxide to L-Methionine (Homo sapiens)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Caenorhabditis elegans)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Dictyostelium discoideum)


name: Activation of Rap1 by cytosolic GEFs (Homo sapiens)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Mus musculus)


name: (20S)-ginsenoside F1 + H(+) + UDP => (20S)-protopanaxatriol + UDP-alpha-D-glucose


name: ADP(out) + diphosphate(in) => ADP(in) + diphosphate(out)


name: catechol + FAD + H(+) + H2O => FADH2 + O2 + phenol


name: ESTG binds ESR2:chaperone complex (Mus musculus)


name: CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Mus musculus)


name: Defective APRT does not convert adenine to AMP (Homo sapiens)


name: PP6 dephosphorylates SEC24 (Xenopus tropicalis)


name: L-erythro-7,8-dihydrobiopterin + NADP(+) = H(+) + NADPH + sepiapterin


name: RAS:GTP binds RAL GDS proteins (Gallus gallus)


name: ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Bos taurus)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Mus musculus)


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Bos taurus)


name: Cleavage of mRNA at the 3'-end (Bos taurus)


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Mus musculus)


name: TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)


name: LRTOMT transfers Met to DA, forming 3MT (Homo sapiens)


name: (2R)-O-phospho-3-sulfolactate = H(+) + phosphoenolpyruvate + sulfite


name: S-adenosyl-L-methionine + serotonin <=> 5-methoxytryptamine + H(+) + S-adenosyl-L-homocysteine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-leucine = H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-leucine


name: 2-dehydro-3-deoxy-L-arabinonate => glycolaldehyde + pyruvate


name: 4-acetamidobutanal + H2O2 + propane-1,3-diamine => H2O + N(8)-acetylspermidine + O2


name: Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: Formation of the Spliceosomal E complex (Homo sapiens)


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Gallus gallus)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Bos taurus)


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA => a ribonucleotidyl-ribonucleotide-RNA


name: Orexin 2 receptor can bind orexin-B neuropeptide (Canis familiaris)


name: H(+)(in) + L-idonate(in) => H(+)(out) + L-idonate(out)


name: 2-oxoglutarate + H(+) => CO2 + succinate semialdehyde


name: (indol-3-yl)acetate(out) + a dicarboxylate(in) => (indol-3-yl)acetate(in) + a dicarboxylate(out)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: HMIT co-transports myo-inositol with a proton (Gallus gallus)


name: Hemes:LY96 activates TLR4 (Gallus gallus)


name: chrodrimanin A + H2O + NADP(+) => chrodrimanin T + H(+) + NADPH + O2


name: Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Xenopus tropicalis)


name: a globoside IV3GalNAc-Gb4Cer + H2O <=> a globoside Gb4Cer + N-acetyl-alpha-D-galactosamine


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Gallus gallus)


name: H2O + NAD(+) = AMP + beta-nicotinamide D-ribonucleotide + 2 H(+)


name: CMP-5'-phosphonoformate + diphosphate => CTP + phosphonoformate


name: H2O + N(5)-[1(S)-1-carboxyethyl]-L-ornithine + NADP(+) = H(+) + L-ornithine + NADPH + pyruvate


name: (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: USP19 deubiquitinates RNF123 (Canis familiaris)


name: ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate => ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine


name: 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA (Rattus norvegicus)


name: CHDH oxidises Cho to BETALD (Caenorhabditis elegans)


name: Activation of Cdc25C (Saccharomyces cerevisiae)


name: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 (Mus musculus)


name: 2-oxo-3-sulfanylpropanoate + L-cysteinyl-[protein] => pyruvate + S-sulfanyl-L-cysteinyl-[protein]


name: 4-sulfobenzoate + NADH + O2 => 3,4-dihydroxybenzoate + NAD(+) + sulfite


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Rattus norvegicus)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Sus scrofa)


name: (S)-S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine = 3-O-acetylpapaveroxine + H(+) + S-adenosyl-L-homocysteine


name: SOCS3 binds activated PTK6 (Homo sapiens)


name: (E,E)-piperate + ATP + H(+) => (E,E)-piperoyl-AMP + diphosphate


name: 1,8-cineole + O2 + reduced [NADPH--hemoprotein reductase] = 2-exo-hydroxy-1,8-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: LHX2,(LHX9) binds the ROBO3 gene promoter (Homo sapiens)


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Bos taurus)


name: MAP1LC3B binds KEAP1 and SQSTM1 (Rattus norvegicus)


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Homo sapiens)


name: Activation of tandem pore domain in a weak inwardly rectifying  K+ channels (Xenopus tropicalis)


name: 1-O-(1Z-13-methyltetradecenyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-O-(13-methyltetradecyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Danio rerio)


name: TREM,CD300 binds lipids (Xenopus tropicalis)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Bos taurus)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Danio rerio)


name: 2 Fe(III)-[cytochrome b5] + H2O + N-tetracosanoyl-(4R)-hydroxysphinganine => 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-tetracosanoylsphinganine + O2


name: all-trans-4-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> all-trans-4-oxoretinoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADPH + presqualene diphosphate = diphosphate + NADP(+) + squalene


name: Aquaporins passively transport urea into cells (Schizosaccharomyces pombe)


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Homo sapiens)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Gallus gallus)


name: Rsu-1 interacts with Pinch1 (Sus scrofa)


name: SLC29A1 transports RBV from extracellular region to cytosol (Xenopus tropicalis)


name: Phosphorylation of PKC theta (Schizosaccharomyces pombe)


name: CHEK2 phosphorylates TP53 (Xenopus tropicalis)


name: (R)-lipoyl-5'-AMP + diphosphate => (R)-lipoate + ATP + H(+)


name: allo-aromadendrene + diphosphate => (2E,6E)-farnesyl diphosphate


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Dictyostelium discoideum)


name: D-glyceraldehyde 3-phosphate + indole => (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate


name: TCR binds self-lipid-based antigen via CD1 (Mus musculus)


name: 2 a menaquinone + n H(+)(out) + 2 H2O(in) => 2 a menaquinol + n H(+)(in) + O2


name: HIPK2 phosphorylates MECP2 (Homo sapiens)


name: ABCB11 transports bile salts from cytosol to extracellular region (Bos taurus)


name: CoA + H(+) + O2 + pyruvate <=> acetyl-CoA + CO2 + H2O2


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Sus scrofa)


name: 1,4-dihydroxy-2-naphthoate + all-trans-nonaprenyl diphosphate + H(+) => 2-demethylmenaquinol-9 + CO2 + diphosphate


name: SHC1 phosphorylation by ERBB2 heterodimers (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> (+)-germacrene D + diphosphate


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Danio rerio)


name: (S)-2-amino-6-oxohexanoate + NH4(+) + phosphate => (5R)-5-phosphooxy-L-lysine + H2O


name: WIPIs bind PI3P (Dictyostelium discoideum)


name: 2 a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycero-3-phospho-1D-myo-inositol


name: NTPDase7 hydrolyzes nucleoside triphosphates (Sus scrofa)


name: Association of procollagen type VII (Homo sapiens)


name: Homodimerization of ERBB4 (Xenopus tropicalis)


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate = (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O


name: FOXO3,FOXO4,(FOXO1) bind BCL6 gene promoter (Homo sapiens)


name: 3,7,11,15-tetramethylhexadecanoate + ATP + CoA => AMP + diphosphate + phytanoyl-CoA


name: Degradation of multiubiquitinated cell cycle proteins (Sus scrofa)


name: H(+) + L-arginine + NADPH + O2 => H2O + N(omega)-hydroxy-L-arginine + NADP(+)


name: dTTP + 2 H2O <=> dTMP + 2 H(+) + 2 phosphate


name: 3-epi-6-deoxocathasterone + O2 + reduced [NADPH--hemoprotein reductase] => 6-deoxotyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CYP8B1 12-hydroxylates 4CHOL7a,27DONE (Sus scrofa)


name: Aggrecan binds Hyaluronan and HAPLN1 (Bos taurus)


name: [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate => [glutamine synthetase]-L-tyrosine + ADP


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + vanillate = 3,4-dihydroxybenzoate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: CDP-DAG is converted to PI by CDIPT (Drosophila melanogaster)


name: ABCA4 mediates atRAL transport (Xenopus tropicalis)


name: SLMB binds to and ubiquitinates phosphorylated CI (Drosophila melanogaster)


name: Binding of ADAR1 homodimer to dsRNA duplex (Bos taurus)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Gallus gallus)


name: H2O + L-arginyl-[protein] => L-citrullyl-[protein] + NH4(+)


name: Phosphorylation of DCC by Fyn (Caenorhabditis elegans)


name: Activation of GT (Schizosaccharomyces pombe)


name: AH2 + chermesin D + O2 <=> A + asnovolin I + H2O


name: (1'S,5'S)-averufin + NADPH + O2 <=> 1'-hydroxyversicolorone + H2O + NADP(+)


name: Activation of p38MAPK by DSCAM (Drosophila melanogaster)


name: morphine + NADP(+) <=> H(+) + morphinone + NADPH


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Drosophila melanogaster)


name: DCC interaction with ROBO1 (Homo sapiens)


name: TP53 and AP-1 bind the MSH2 promoter (Homo sapiens)


name: butan-2-one + hydrogen cyanide <=> 2-hydroxy-2-methylbutanenitrile


name: Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma (Homo sapiens)


name: Phosphorylation of SHC by SYK kinase (Sus scrofa)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Xenopus tropicalis)


name: DHRS7B reduces GO3P to HXDG3P (Danio rerio)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Canis familiaris)


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + N-(2,3-dihydroxybenzoyl)-L-serine => Fe(III)-{di[N-(2,3-dihydroxybenzoyl)-L-seryl]-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + H(+) + H2O


name: ethyl hexadecanoate + H2O <=> ethanol + H(+) + hexadecanoate


name: follicle-stimulating hormone receptor binding


name: cis-4-hydroxy-D-proline betaine => trans-4-hydroxy-L-proline betaine


name: 4-hydroxy-all-trans-beta-carotene + A + H2O => AH2 + all-trans-beta-carotene + O2


name: GABAB heterodimeric receptor binds GABA (Homo sapiens)


name: RASA1 stimulates RAS GTPase activity (Canis familiaris)


name: L-threonine + uridine-5'-aldehyde <=> (5'S,6'R)-C-glycyluridine + acetaldehyde


name: 5,6-dihydrouridine(47) in tRNA + NAD(+) = H(+) + NADH + uridine(47) in tRNA


name: D-galactaro-1,4-lactone <=> 5-dehydro-4-deoxy-D-glucarate + H(+)


name: Caspase mediated cleavage of alpha-II-Fodrin (Rattus norvegicus)


name: Aquaporin-3 passively transports water out of cell (Plasmodium falciparum)


name: cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Danio rerio)


name: Internal Methylation of mRNA (Plasmodium falciparum)


name: 3 a ubiquinone + protoporphyrinogen IX => 3 a ubiquinol + protoporphyrin IX


name: (2S)-2-acetolactate + thiamine diphosphate => 2-(1-hydroxyethyl)thiamine diphosphate + pyruvate


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-lysyl-tRNA(Lys) => 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys)


name: rhamnetin + S-adenosyl-L-methionine = H(+) + rhamnacene + S-adenosyl-L-homocysteine


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Gallus gallus)


name: dATP + H2O <=> dAMP + diphosphate + H(+)


name: C-C motif chemokine 21 receptor activity


name: dichloromethane + H2O => 2 chloride + formaldehyde + 2 H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O <=> a 2-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: 3,4-dihydroxyphenylacetate + O2 = 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)


name: Secretion of collagens (Rattus norvegicus)


name: H2O + L-alanyl-L-glutamate => L-alanine + L-glutamate


name: SETD6 methylates RELA in the NFkB complex (Mus musculus)


name: P2Y14 receptor can bind to UDP-glucose (Gallus gallus)


name: cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + cholesterol


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP => (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate


name: pre-VLDL binds lipids to form VLDL (Canis familiaris)


name: ADP(out) + H(+)(out) + phosphate(in) <=> ADP(in) + H(+)(in) + phosphate(out)


name: METAP1/2 demethylates GNAT1 (Bos taurus)


name: Coumarin is 7-hydroxylated by CYP2A13 (Canis familiaris)


name: ADP-1-deoxy-1,O(4)-didehydro-D-ribose + nicotinamide => NAD(+)


name: (E)-cinnamyl alcohol + acetyl-CoA => (E)-cinnamyl acetate + CoA


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = 12-epi-fischerindole U


name: Serum albumin binds 2-lysophosphatidylcholine (Mus musculus)


name: Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Canis familiaris)


name: PTPN3 dephosphorylates EPS15 (Rattus norvegicus)


name: 2-all-trans-hexaprenylphenol + CO2 => 4-hydroxy-3-all-trans-hexaprenylbenzoate + H(+)


name: Association of procollagen type XI (Rattus norvegicus)


name: an (11E)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: VEGFA-165 dimer binds VEGFA inhibitors (Bos taurus)


name: Basigin binds Matrix metalloproteinase-1 (Sus scrofa)


name: a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Caenorhabditis elegans)


name: 2,2-dialkylglycine + H(+) + pyruvate = CO2 + dialkyl ketone + L-alanine


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Sus scrofa)


name: Activated FGFR3:p-SHC1 binds GRB2:SOS1 (Bos taurus)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin] <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: E2F1 binds the RRM2 gene promoter (Homo sapiens)


name: BOD1L1 binds SET1A complex (Canis familiaris)


name: ABHD10 hydrolyses MPAG (Xenopus tropicalis)


name: 12-octadecanoyloxy-octadecanoate + H2O => 12-hydroxyoctadecanoate + H(+) + octadecanoate


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Mus musculus)


name: N-terminal L-glutaminyl-[peptide] => N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)


name: IRAK2 binds to IRAK4 associated with activated TLR : MyD88 complex (Gallus gallus)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Schizosaccharomyces pombe)


name: dihydromonacolin L carboxylate + H(+) + holo-[lovastatin nonaketide synthase] => dihydromonacolin L-[lovastatin nonaketide synthase] + H2O


name: Plasma membrane resorption (Canis familiaris)


name: 4 (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine = 8 AMP + 8 diphosphate + 8 H(+) + PF1022F + 4 S-adenosyl-L-homocysteine


name: 2 3',4'-dihydroxyaurone + 2 H2O => 2 2',3,4-trihydroxy-trans-chalcone + 2 H(+) + O2


name: Translocation of Cdc25 to the nucleus (Saccharomyces cerevisiae)


name: TFAP2A binds TFAP2B (Drosophila melanogaster)


name: Some HSPGs are secreted to the plasma membrane (Mus musculus)


name: (1S,4S)-bornane-2,5-dione + FMNH2 + O2 => (1S,4S)-5-oxo-1,2-campholide + FMN + H(+) + H2O


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Sus scrofa)


name: GSTO dimers reduce DeHA to AscH- (Caenorhabditis elegans)


name: The ABCC family mediates organic anion transport (Canis familiaris)


name: cordypyrone A + O2 + reduced [NADPH--hemoprotein reductase] <=> cordypyrone B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + 9-hydroxy-octadecanoate = 9-(9Z,12Z-octadecadienoyloxy)-octadecanoate + di-(9Z,12Z)-octadecadienoylglycerol


name: (S)-acetoin + H(+) + NADH => (S,S)-butane-2,3-diol + NAD(+)


name: ADP + thiamine diphosphate = AMP + thiamine triphosphate


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Dictyostelium discoideum)


name: T2Rs bind bitter-tasting compounds (Homo sapiens)


name: 2 hydrogencarbonate(out) + sulfate(in) <=> 2 hydrogencarbonate(in) + sulfate(out)


name: 4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine => H(+) + isowyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine


name: SLC16A10-mediated uptake of aromatic amino acids (Homo sapiens)


name: IL17RD binds p-2S MAP2Ks and MAPKs (Canis familiaris)


name: (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+) => (+)-dehydrodiconiferyl acid + 2 a quinone + H2O


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Rattus norvegicus)


name: Persulfide sulfur is dioxygenated (Homo sapiens)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-heptadecanoyl-sn-glycero-3-phosphate = 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA


name: chloride + L-tyrosine + NADP(+) = 3-chloro-L-tyrosine + NADPH


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Rattus norvegicus)


name: loganate + S-adenosyl-L-methionine = loganin + S-adenosyl-L-homocysteine


name: RHOA:GTP:RTKN binds TAX1BP3 (Gallus gallus)


name: Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)


name: ATP + cycloheximide(in) + H2O = ADP + cycloheximide(out) + H(+) + phosphate


name: H2O2 + N,N'-diacetylchitobiono-1,5-lactone => N,N'-diacetylchitobiose + O2


name: Interaction of Tie2 and Dok-2 (Sus scrofa)


name: [thioredoxin]-disulfide + H2O + tert-butanol => [thioredoxin]-dithiol + tert-butyl hydroperoxide


name: Removal of siRNA passenger strand (Gallus gallus)


name: H(+)(out) + L-lysine(out) <=> H(+)(in) + L-lysine(in)


name: Interaction of NCAM1 with GFRalpha-1 (Homo sapiens)


name: FAD + H(+) + hexanoyl-CoA <=> (2E)-hexenoyl-CoA + FADH2


name: Activation of Ca permeable AMPA receptors (Rattus norvegicus)


name: 3-methylbutanoyl-CoA + H2O <=> 3-methylbutanoate + CoA + H(+)


name: protein tyrosine phosphatase activity, via thiol-phosphate intermediate


name: Exocytosis of azurophil granule membrane proteins (Dictyostelium discoideum)


name: TP53RK phosphorylates TP53 (Rattus norvegicus)


name: DDX5 binds ESR1:estrogen:TFF1 gene promoter (Drosophila melanogaster)


name: 3beta-hydroxy-5alpha-androstane-7,17-dione + H(+) + NADPH = 3beta,7beta-dihydroxy-5alpha-androstan-17-one + NADP(+)


name: UDP-glucose is oxidised to UDP-glucuronate (Danio rerio)


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Homo sapiens)


name: p-Y694-STAT5A, p-STAT5B dimerizes (Canis familiaris)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Caenorhabditis elegans)


name: ATG12 binds ATG7 dimer (Xenopus tropicalis)


name: a ubiquinone + formate + H(+) <=> a ubiquinol + CO2


name: MKL1 translocates from cytosol to the nucleus (Homo sapiens)


name: LTA4 is converted to LTC4 by LTC4S (Mus musculus)


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Canis familiaris)


name: D-galactaro-1,5-lactone + H(+) + NADH => beta-D-galacturonate + NAD(+)


name: 2-dehydro-3-deoxy-L-galactonate => L-glyceraldehyde + pyruvate


name: CFHR dimers bind C3b (Xenopus tropicalis)


name: CFTR transits to the plasma membrane (Plasmodium falciparum)


name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Sus scrofa)


name: 2 H(+)(in) + H2 + menaquinone-8 <=> 2 H(+)(out) + menaquinol-8


name: histone H3K36 methyltransferase activity


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: prostaglandin E2 => H2O + prostaglandin A2


name: acetyl-CoA + octopamine = CoA + H(+) + N-acetyloctopamine


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Plasmodium falciparum)


name: [Rab1 protein]-L-serine + CDP-choline = [Rab1 protein]-O-phosphocholine-L-serine + CMP + H(+)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Homo sapiens)


name: PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Saccharomyces cerevisiae)


name: 12,13-epoxy-(9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-12,13-epoxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Gallus gallus)


name: acetyl-[ACP] + CoA => acetyl-CoA + holo-[ACP]


name: H(+) + linamarin + UDP => 2-hydroxy-2-methylpropanenitrile + UDP-alpha-D-glucose


name: The phagophore extends from the PIP3-enriched structure (Homo sapiens)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Danio rerio)


name: β1,2-agonists bind ADRB1,2 (Rattus norvegicus)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 => (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-eicosatrienoate


name: (E)-4-hydroxynon-2-enal + H2O + O2 = (E)-4-hydroxynon-2-enoate + H(+) + H2O2


name: 5-methylcytidine(34) in mitochondrial tRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(34) in mitochondrial tRNA + S-adenosyl-L-methionine


name: D-ribulose 5-phosphate => D-xylulose 5-phosphate


name: H2O + tridecanoylglycerol <=> 2,3-didecanoyl-sn-glycerol + decanoate + H(+)


name: 1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: lithocholate + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxylithocholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Autophosphorylation of PDGF beta receptors (Bos taurus)


name: DCC interacting NCK-1 (Rattus norvegicus)


name: Formation of the SET1A complex (Sus scrofa)


name: deoxyherqueinone + H(+) + NADPH + O2 => H2O + herqueinone + NADP(+)


name: H(+)(out) + inosine(in) => H(+)(in) + inosine(out)


name: BRF1 Complex recruits RNA degradation activities (Gallus gallus)


name: Binding of RRN3 to RNA Polymerase I (Mus musculus)


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Gallus gallus)


name: 4-O-[(D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-alpha-D-glucose = 4-O-[(2-beta-D-glucosyl-D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: 4,4-dihydroxy-all-trans-beta-carotene <=> echinenone + H2O


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Mus musculus)


name: Deletions in the AXIN1 gene prevent expression of AXIN1 protein (Homo sapiens)


name: IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Rattus norvegicus)


name: AKT binds PDPK1 (Schizosaccharomyces pombe)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Gallus gallus)


name: Interaction of MEKK1 with TRAF6 (Homo sapiens)


name: RNF181 binds BCL10 and Ubiquitin:E2 (Bos taurus)


name: p-S303,307-HSF1 binds YWHAE (14-3-3) (Schizosaccharomyces pombe)


name: AKT1 binds eNOS complex via HSP90 (Rattus norvegicus)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(9)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(9)-[histone H3] + succinate


name: Activated FGFR3 phosphorylates PPTN11 (Bos taurus)


name: H2O + juglone = naphthalene-1,2,4,8-tetrol


name: AH2 + decanoyl-[ACP] + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine => 2,4-dihydroxy-3-methyl-6-(2-oxoundecyl)benzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP] + S-adenosyl-L-homocysteine


name: lithocholoyl-CoA + ursodeoxycholate => lithocholate + ursodeoxycholoyl-CoA


name: KPNA2 translation is negatively regulated by miR-26A and B (Homo sapiens)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Dictyostelium discoideum)


name: D-methionine + pyruvate <=> 4-methylsulfanyl-2-oxobutanoate + L-alanine


name: an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose <=> a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+)


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Canis familiaris)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Xenopus tropicalis)


name: 2 A + canthaxanthin + 3 H2O => 2 AH2 + echinenone + 2 O2


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Xenopus tropicalis)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Dictyostelium discoideum)


name: 3,8-divinyl protochlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => 2 oxidized [2Fe-2S]-[ferredoxin] + protochlorophyllide a


name: p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 (Mus musculus)


name: SUMOylation of NFKB2 with SUMO1 (Mus musculus)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Homo sapiens)


name: ALK binds ligand midkine (MDK) (Bos taurus)


name: LRRC16A binds F-actin capping protein (Drosophila melanogaster)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Mus musculus)


name: (2E)-decenoyl-CoA + H2O <=> 3-hydroxydecanoyl-CoA


name: SIRT5 deacetylates Cytochrome C (Gallus gallus)


name: Defective ATRX does not bind DAXX (Homo sapiens)


name: cholesterol + glycyl-L-cysteinyl-[protein] + H(+) => [protein]-C-terminal glycyl cholesterol ester + N-terminal L-cysteinyl-[protein]


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Saccharomyces cerevisiae)


name: Interleukin-2 receptor alpha binds interleukin-2 (Rattus norvegicus)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Sus scrofa)


name: spindle pole body-nuclear membrane anchor activity


name: alpha,alpha-trehalose 6-phosphate + phosphate => beta-D-glucose 1-phosphate + D-glucose 6-phosphate


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-phosphate + ATP = a 2'-deoxyribonucleoside 5'-diphosphate + ADP


name: ERBB2 T862A does not bind sapitinib (Homo sapiens)


name: IER3 recruits MAPKs to PP2A-B56-beta,gamma (Canis familiaris)


name: 1-hexadecanoylglycerone 3-phosphate + octadecan-1-ol = 1-O-octadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: platelet-derived growth factor receptor activity


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: BORA binds PLK1 and AURKA (Rattus norvegicus)


name: 3'-dephospho-CoA + GTP = CoA + GDP + H(+)


name: GUSB tetramer hydrolyses CS/HS precursor (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + 2 H2O <=> 2 a carboxylate + 2 H(+) + sn-glycero-3-phosphoethanolamine


name: The 60S subunit joins the translation initiation complex  (Saccharomyces cerevisiae)


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Sus scrofa)


name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Bos taurus)


name: BLT receptors can bind LTB4 (Sus scrofa)


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Gallus gallus)


name: PIAS1,4 SUMOylates BRCA1 with SUMO2,3 (Rattus norvegicus)


name: guanosine(2535) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylguanosine(2535) in 23S rRNA + S-adenosyl-L-homocysteine


name: Formation of collagen networks (Gallus gallus)


name: H(+) + oxidized [electron-transfer flavoprotein] + pentadecanoyl-CoA => (2E)-pentadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: AMP + diphosphate + L-aspartyl-tRNA(Asx) => ATP + L-aspartate + tRNA(Asx)


name: Activation of claspin (Drosophila melanogaster)


name: a medium-chain primary fatty alcohol + NADP(+) <=> a medium-chain fatty aldehyde + H(+) + NADPH


name: H2O + L-threonyl-tRNA(Ser) = L-threonine + tRNA(Ser)