name: ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate <=> ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine


name: Corticosteroids bind to CBG in blood (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate = (+)-gamma-cadinene + diphosphate


name: ARL2:GTP:ARL2BP binds SLC25A4 (Sus scrofa)


name: Degradation of newly synthesized ApoB-48 (Canis familiaris)


name: 2-oxoglutarate + CoA + NAD(+) <=> CO2 + NADH + succinyl-CoA


name: Activation of Rap1 by membrane-associated GEFs (Bos taurus)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-GlcNAc + GDP + H(+) => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-GlcNAc + GDP-beta-L-fucose


name: (Z)-beta-ocimene + diphosphate => (2E)-geranyl diphosphate


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Rattus norvegicus)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) = (6R)-L-erythro-6,7-dihydrobiopterin + H(+) + NADPH


name: ADP + Cu(+)(out) + H(+) + phosphate => ATP + Cu(+)(in) + H2O


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Saccharomyces cerevisiae)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Xenopus tropicalis)


name: H2O + methylglyoxal + O2 <=> H(+) + H2O2 + pyruvate


name: Ubiquitination of stimulated EGFR (CBL) (Canis familiaris)


name: acetate + androst-4-ene-3,17-dione + H2O + NADP(+) => 17alpha-hydroxyprogesterone + NADPH + O2


name: (2E)-tetradecenoyl-CoA + H(+) + NADPH <=> NADP(+) + tetradecanoyl-CoA


name: Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: 4-O-feruloyl-D-quinate + CoA => (E)-feruloyl-CoA + L-quinate


name: ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A <=> ADP + an L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Bos taurus)


name: acetyl phosphate + L-lysyl-[protein] => H(+) + N(6)-acetyl-L-lysyl-[protein] + phosphate


name: Iodide is taken up by thyroid epithelial cells (Caenorhabditis elegans)


name: NTPDase2 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: ATP + H2O + N-acetyl-L-aspartate(in) => ADP + H(+) + N-acetyl-L-aspartate(out) + phosphate


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + octadecanoate


name: (S)-3-methyl-2-oxopentanoate + H2O => (2R,3R)-2,3-dihydroxy-3-methylpentanoate


name: proton-dependent oligopeptide secondary active transmembrane transporter activity


name: WWTR1:SMAD translocates to the nucleus (Rattus norvegicus)


name: Formation of Cyclin E:Cdk2 complexes (Homo sapiens)


name: a ganglioside GM2 + H(+) + UDP => a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine


name: GUSB tetramer hydrolyses (HA)2 (Xenopus tropicalis)


name: cyclobutadithymidine in DNA = a thymidine dimer in DNA


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Caenorhabditis elegans)


name: [deoxyhypusine synthase]-L-lysine + dehydrospermidine <=> [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine


name: GABA translocates from cytosol to mitochondrial matrix (Homo sapiens)


name: SUMOylation of HIPK2 with SUMO1 (Saccharomyces cerevisiae)


name: Hemoglobin A binds O2, releasing H+ and CO2 (Danio rerio)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Schizosaccharomyces pombe)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Rattus norvegicus)


name: acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Bos taurus)


name: RAS mutants bind inactive RAF (Homo sapiens)


name: OGG1beta translocates to mitochondria (Dictyostelium discoideum)


name: Phosphorylation of cPLA2 by ERK-2 (Sus scrofa)


name: guanine(in) + Na(+)(in) => guanine(out) + Na(+)(out)


name: 2-oxoglutarate + H(+) + isochorismate => 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2


name: D-ribose + H2O + NADP(+) = D-ribonate + 2 H(+) + NADPH


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Bos taurus)


name: SUMOylation of NPM1 with SUMO1 (Mus musculus)


name: "N-terminal L-serine N(alpha)-acetyltransferase NatD"


name: AFG3L2 degrades mitochondrial matrix proteins (Homo sapiens)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Canis familiaris)


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + ATP = 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + ADP + H(+)


name: ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Schizosaccharomyces pombe)


name: (2E)-docosenoyl-CoA + H(+) + NADPH <=> docosanoyl-CoA + NADP(+)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Gallus gallus)


name: crocetin + UDP-alpha-D-glucose = beta-D-glucosyl crocetin + UDP


name: GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Mus musculus)


name: H2O + N-amidino-L-aspartate = L-aspartate + urea


name: uridine(2605) in 23S rRNA => pseudouridine(2605) in 23S rRNA


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Canis familiaris)


name: alpha-D-glucose + D-maltotriose => D-maltotetraose + H2O


name: (deoxy)nucleoside phosphate kinase activity, GTP as phosphate donor


name: a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP


name: AH2 + gluconapin + O2 = A + H2O + progoitrin


name: Addition of GlcNAc to the glycan on the A arm (Mus musculus)


name: MAGED1 binds NPAS4 (Drosophila melanogaster)


name: P2X7 mediates membrane pores that include pannexin-1 (Mus musculus)


name: KW2449-resistant FLT3 mutants don't bind KW2449 (Homo sapiens)


name: Assembly of the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)


name: D-xylulose 5-phosphate + phosphate => acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O


name: Activation of Calcineurin (Drosophila melanogaster)


name: Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) (Rattus norvegicus)


name: (2R,3S)-catechin + H2O + NADP(+) <=> (2R,3S,4S)-leucocyanidin + H(+) + NADPH


name: n H(+)(out) + spermidine(in) => n H(+)(in) + spermidine(out)


name: (E)-non-2-enal + H2O + NAD(+) => (E)-non-2-enoate + 2 H(+) + NADH


name: L-kynurenine + pyruvate = H2O + kynurenate + L-alanine


name: SERPING1 is secreted (Drosophila melanogaster)


name: H2O + N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein] <=> glycolate + H(+) + L-arginyl-[protein]


name: AcK-NFE2L2 binds the BCL2 gene (Homo sapiens)


name: coproporphyrin III(out) = coproporphyrin III(in)


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: DYRK2 phosphorylates TP53 (Canis familiaris)


name: AFG3L2:SPG7 binds SMDT1 (EMRE) (Homo sapiens)


name: Formation of Okazaki fragments (Bos taurus)


name: 2,6,10,14-tetramethylpentadecanoate + ATP + CoA = AMP + diphosphate + pristanoyl-CoA


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GUK1 phosphorylates 6TGMP to 6TGDP (Homo sapiens)


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Canis familiaris)


name: SLC52A1,2,3 transport RIB from extracellular region to cytosol (Bos taurus)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Bos taurus)


name: alpha-D-Abe-(1->3)-alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+) => alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-choline => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: SHC1 bound to IL2 receptor is phosphorylated (Rattus norvegicus)


name: ATPase-coupled carboxylic acid transmembrane transporter activity


name: (R)-metanephrine + H(+) + S-adenosyl-L-homocysteine => (R)-adrenaline + S-adenosyl-L-methionine


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Sus scrofa)


name: 2-oxoglutarate + 5-dehydro-6-demethoxyfumagillol + O2 = 5-dehydro-6-demethoxy-6-hydroxyfumagillol + CO2 + succinate


name: PDP dephosphorylates p-lipo-PDH (Bos taurus)


name: DDR2 binds collagen type I, II, III, V, X fibrils (Canis familiaris)


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate <=> (Z)-alpha-bisabolene + diphosphate


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(34-hydroxytetratriacontadienoyl)-sphing-4-enine = a diacylglycerol + an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontadienoyl)-sphing-4-enine


name: Activation of conventional Protein Kinase C (Rattus norvegicus)


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Saccharomyces cerevisiae)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Xenopus tropicalis)


name: 7beta-hydroxy-3,12-dioxo-5beta-cholan-24-oate + NADP(+) <=> dehydrocholate + H(+) + NADPH


name: Deacetylation of cohesin (Saccharomyces cerevisiae)


name: Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA (Bos taurus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)


name: 5-phosphomethyl-dUMP in DNA + glycine = 5-N(alpha)-glycyl-dTMP in DNA + phosphate


name: Furin cleaves pro-factor VII to factor VII (Homo sapiens)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Drosophila melanogaster)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Canis familiaris)


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Canis familiaris)


name: GIP receptor binds gastric inhibitory peptide (Xenopus tropicalis)


name: H(+) + N(6)-(dimethylallyl)adenosine 5'-triphosphate + NADPH + O2 <=> 9-ribosyl-trans-zeatin 5'-triphosphate + H2O + NADP(+)


name: snRNA 2'-O-ribose methyltransferase activity


name: (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H(+) => 1,3-di-(9Z-octadecenoyl)-glycerol + H2O


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Canis familiaris)


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Gallus gallus)


name: biotinyl-5'-AMP + L-lysyl-[protein] = AMP + 2 H(+) + N(6)-biotinyl-L-lysyl-[protein]


name: 7-methylmellein + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 7-carboxymellein + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-3-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol


name: 1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate


name: 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O => 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol


name: RHOA binds effectors at the ER membrane (Mus musculus)


name: IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Canis familiaris)


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Dictyostelium discoideum)


name: glycerol + H(+) + phosphocholine => H2O + sn-glycerol 3-phosphocholine


name: (2-aminoethyl)phosphonate + CTP => CMP-(2-aminoethyl)phosphonate + diphosphate


name: DREAM complex binds the TOP2A gene promoter (Homo sapiens)


name: Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Rattus norvegicus)


name: p-S407,Y641-STAT6 is dimerized (Mus musculus)


name: hydrogen sulfide + O-succinyl-L-serine <=> L-cysteine + succinate


name: ABCAs mediate lipid influx (Dictyostelium discoideum)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Caenorhabditis elegans)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Mus musculus)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Dictyostelium discoideum)


name: Defective RHAG does not transport NH4+ from cytosol to extracellular region (rbc) (Homo sapiens)


name: NADP(+) <=> 2'-phospho-cyclic ADP-ribose + nicotinamide


name: H2O + L-arginine <=> L-citrulline + NH4(+)


name: Initial activation of proMMP1 (Caenorhabditis elegans)


name: TRAF6 binds MALT1 oligomers (Homo sapiens)


name: GDP + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n+1) + phosphate => GTP + L-glutamate + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine => D-histidine + S-adenosyl-L-methionine


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + nonadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA


name: Dimerization of STATs (Canis familiaris)


name: adenine + D-ribose 5-triphosphate => ATP + H2O


name: a (3R)-hydroxyacyl-[ACP] + NAD(+) <=> a 3-oxoacyl-[ACP] + H(+) + NADH


name: Collagen types VI, IX bind integrin alpha10beta1 (Xenopus tropicalis)


name: Activation of RAC1 by VAV (Drosophila melanogaster)


name: (R)-3-hydroxybutanoate + [(3R)-hydroxybutanoate](n-1) + H(+) => [(3R)-hydroxybutanoate](n) + H2O


name: A + cholest-4,6-dien-3-one + H2O <=> 25-hydroxycholest-4,6-dien-3-one + AH2


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Caenorhabditis elegans)


name: adenosine in U6 snRNA + CO2 + formaldehyde + succinate => 2-oxoglutarate + N(6)-methyladenosine in U6 snRNA + O2


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Rattus norvegicus)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Mus musculus)


name: adenosylcob(III)alamin 5'-phosphate + H2O => adenosylcob(III)alamin + phosphate


name: H2O + methylglyoxal + NAD(+) = 2 H(+) + NADH + pyruvate


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Canis familiaris)


name: Acidification of Tf:TfR1 containing endosome (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate => (1S,8aR)-delta-cadinene + diphosphate


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate => 11-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate + H2O => beta-eudesmol + diphosphate


name: dihydroprecondylocarpine acetate + NADP(+) <=> H(+) + NADPH + precondylocarpine acetate


name: 2 H(+) + hexadecanoyl-[ACP] + 2 NADPH <=> hexadecan-1-ol + holo-[ACP] + 2 NADP(+)


name: CoA-dependent peptidyl-lysine N6-palmitoyltransferase activity


name: hexadecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] = CoA + H(+) + N(6)-hexadecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: 1D-myo-inositol 1,2,3-trisphosphate + H2O <=> 1D-myo-inositol 2,3-bisphosphate + phosphate


name: L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH


name: an N-acetyl-L-cysteine-S-conjugate + H2O => acetate + an S-substituted L-cysteine


name: D-arabinitol + NADP(+) => D-xylulose + H(+) + NADPH


name: 2xTPK1:Mg2+ phosphorylates THMN (Plasmodium falciparum)


name: 2-oxoglutarate + O2 + preaustinoid A1 => CO2 + H2O + preaustinoid A2 + succinate


name: AMP + diphosphate + H(+) + phosphoenolpyruvate => ATP + phosphate + pyruvate


name: TCF:Beta-catenin binds SOX proteins (Danio rerio)


name: RUNX3 binds SMAD3 and SMAD4 (Homo sapiens)


name: a sphingoid base + tetracosanoyl-CoA = an N-tetracosanoyl-sphingoid base + CoA + H(+)


name: 5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA => 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate


name: RAC2 binds effectors at the mitochondrial outer membrane (Homo sapiens)


name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region (Drosophila melanogaster)


name: RGS proteins bind GNB5 and CCT/TRiC (Rattus norvegicus)


name: Conversion of Glycerol to Glycerol-3-phosphate (Canis familiaris)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Bos taurus)


name: Deubiquitination of RNF41 by P-USP8 (Dictyostelium discoideum)


name: ub-GLI is degraded by the proteasome (Homo sapiens)


name: Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Mus musculus)


name: ADP + beta-nicotinamide D-ribonucleotide + H(+) => ATP + beta-nicotinamide D-riboside


name: glycocholate(out) + n H(+)(out) => glycocholate(in) + n H(+)(in)


name: a cytidine in mRNA + H(+) + H2O <=> a uridine in mRNA + NH4(+)


name: Proinsulin translocates from the endoplasmic reticulum to the Golgi (Sus scrofa)


name: Exocytosis of specific granule lumen proteins (Dictyostelium discoideum)


name: VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: a 3beta-hydroxy-Delta(5)-steroid + NADP(+) <=> a 3-oxo-Delta(5)-steroid + H(+) + NADPH


name: isopyridoxal + NAD(+) <=> 5-pyridoxolactone + H(+) + NADH


name: Defective CYP11B2 does not oxidise 18HCORST (Homo sapiens)


name: RUNX1 binds the SWI/SNF complex (Drosophila melanogaster)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + H(+) + NADPH => 11beta,17beta-dihydroxyandrost-4-ene-3-one + NADP(+)


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Rattus norvegicus)


name: 2-oxoglutarate + N(6)-acetyl-L-lysine => 6-acetamido-2-oxohexanoate + L-glutamate


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Canis familiaris)


name: glutathione + prostaglandin A2 => prostaglandin A2-S-(S)-glutathione


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Danio rerio)


name: H2O + isopyridoxal + NAD(+) => 5-pyridoxate + 2 H(+) + NADH


name: H2O + N(6)-(2E)-butenoyl-L-lysyl-[protein] => (2E)-2-butenoate + L-lysyl-[protein]


name: chloride(out) + 2 Na(+)(out) + O-butanoyl-(R)-carnitine(out) => chloride(in) + 2 Na(+)(in) + O-butanoyl-(R)-carnitine(in)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Xenopus tropicalis)


name: WNT ligands traffic to the plasma membrane (Bos taurus)


name: Passive I- efflux mediated by SMCT1 (Drosophila melanogaster)


name: 3'-phosphoadenylyl sulfate + taurocholate = adenosine 3',5'-bisphosphate + H(+) + taurocholate 7-sulfate


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-6-sulfooxy-glucosaminyl derivative + GDP + H(+) => a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-6-sulfooxy-glucosaminyl derivative + GDP-beta-L-fucose


name: (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O <=> (2Z)-2-hydroxypenta-2,4-dienoate + fumarate + H(+)


name: ERBB2 KD mutants do not bind osimertinib (Homo sapiens)


name: 4-oxo-4-(pyridin-3-yl)butanal + H2O + NADP(+) = 4-oxo-4-(pyridin-3-yl)butanoate + 2 H(+) + NADPH


name: 4'''-demalonylsalvianin + malonyl-CoA <=> CoA + salvianin


name: Detachment of WASP/WAVE (Xenopus tropicalis)


name: Pannexin 1/Pannexin2 mediated neuronal gap junction communication (Mus musculus)


name: cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine => 5-methylcytidine(72) in tRNA(Thr) + H(+) + S-adenosyl-L-homocysteine


name: L-phenylalanine(out) + Na(+)(out) => L-phenylalanine(in) + Na(+)(in)


name: 2 L-dopa + O2 => 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+)


name: N-phenylhydroxylamine + NADP(+) = H(+) + NADPH + nitrosobenzene


name: 2 Fe(III)-[cytochrome c3] + hydrogen sulfide + sulfite <=> 2 Fe(II)-[cytochrome c3] + thiosulfate


name: hexadecanoyl-CoA + sn-glycerol 3-phosphate => 1-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate (Xenopus tropicalis)


name: 6-methylpretetramide + 2 H(+) + NADPH + O2 => 4-hydroxy-6-methylpretetramide + H2O + NADP(+)


name: glycine + urea => guanidinoacetate + H2O


name: (3E)-4,8-dimethylnona-1,3,7-triene + but-3-en-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (3S,6E)-nerolidol + O2 + reduced [NADPH--hemoprotein reductase]


name: p-STAT5 dissociates from the receptor complex (Canis familiaris)


name: ent-kaur-16-en-19-oate + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = gibberellin A12 + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Expression of EOMES in the primitive streak (Homo sapiens)


name: STAT3 binds to p-Y-IL23R in IL23:IL23 receptor (Homo sapiens)


name: IL6 gene produces IL6 protein (Homo sapiens)


name: dipicolinate + H(+) + NADPH => (S)-2,3-dihydrodipicolinate + NADP(+)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Dictyostelium discoideum)


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine => 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: selenate adenylyltransferase (ATP) activity


name: H2SeO4 is converted to APSe by PAPSS1,2 (Homo sapiens)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Homo sapiens)


name: carbamoyl phosphate + L-lysine = H(+) + L-homocitrulline + phosphate


name: AICAR + 10-Formyl-THF => FAICAR + THF (Homo sapiens)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Mus musculus)


name: (3S)-hydroxy-3-methylglutaryl-CoA <=> 3-methyl-(2E)-glutaconyl-CoA + H2O


name: Alternative endo-mannosidase I route (Rattus norvegicus)


name: PGG2 is reduced to PGH2 by PTGS1 (Xenopus tropicalis)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Mus musculus)


name: trans-Golgi Network Coat Assembly (Gallus gallus)


name: Activated FGFR3 binds FRS2 (Homo sapiens)


name: SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate (Canis familiaris)


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene = H2O + rhodopin


name: ADP-D-ribose + H2O = AMP + D-ribose 5-phosphate + 2 H(+)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Gallus gallus)


name: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = 4-carboxy-2-hydroxy-cis,cis-muconate + H2O


name: H(+) + N-(15Z-tetracosenoyl)-sphing-4-enine + phosphocholine => H2O + N-(15Z-tetracosenoyl)sphing-4-enine-1-phosphocholine


name: 1-acyl-2-hexadecenoyl-sn-glycero-3-phosphate + H2O = 2-hexadecenoyl-sn-glycero-3-phosphate + a fatty acid + H(+)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Schizosaccharomyces pombe)


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Bos taurus)


name: The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CCNA2 gene promoter (Homo sapiens)


name: 1-dehydro-L-sorbose + AH2 => A + L-sorbopyranose


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Danio rerio)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Rattus norvegicus)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Dictyostelium discoideum)


name: Expression of Mevalonate Kinase (MVK) (Homo sapiens)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Drosophila melanogaster)


name: beta-L-fucose 1-phosphate + GTP + H(+) => diphosphate + GDP-beta-L-fucose


name: GDP-alpha-D-rhamnose + NAD(+) <=> GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADH


name: FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Homo sapiens)


name: [4-(6-methylheptanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate + H(+) + NADPH => [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate + NADP(+)


name: (2E,6E)-farnesol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: ATP + CoA + lithocholate = AMP + diphosphate + lithocholoyl-CoA


name: BORA binds PLK1 and AURKA (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + H(+) + phosphate


name: a 1-acyl-sn-glycero-3-phosphate + NADP(+) => a 1-acylglycerone 3-phosphate + H(+) + NADPH


name: NDUF subunits bind to form the IP subcomplex (Mus musculus)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Rattus norvegicus)


name: 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 27 H(+) + 9 malonyl-CoA + 18 NADPH => 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate synthase] + 9 CO2 + 9 CoA + 9 H2O + 18 NADP(+)


name: H(+) + NADH + O2 + toluene = 4-methylphenol + H2O + NAD(+)


name: 3-hydroxytetradecanoyl-CoA + AMP + diphosphate => 3-hydroxytetradecanoate + ATP + CoA


name: DHFR dimer binds DHFR inhibitors (Homo sapiens)


name: (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H2O = (Z)-1-(glycyl-L-cystein-S-yl)-2-phenylacetohydroximate + L-glutamate


name: AKT1 phosphorylates NOTCH4 (Mus musculus)


name: H(+) + L,L-cystathionine + succinate => L-cysteine + O-succinyl-L-homoserine


name: a fatty acid + all-trans-retinol + H(+) => an all-trans-retinyl ester + H2O


name: H2O + lactose 6-phosphate = beta-D-glucose + D-galactose 6-phosphate


name: 2 methanethiol + NAD(+) = dimethyl disulfide + H(+) + NADH


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Saccharomyces cerevisiae)


name: N-hexanoyl-sphing-4-enine-1-phosphocholine = choline + N-(hexanoyl)-sphing-4-enine-1,3-cyclic phosphate


name: H2O + sn-glycerol 3-phosphocholine => glycerol + H(+) + phosphocholine


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Mus musculus)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Rattus norvegicus)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Canis familiaris)


name: FGFR3c binds to FGF (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA => (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: acetyl-CoA + 3 H(+) + 3 malonyl-CoA => 4 CO2 + 4 CoA + orcinol


name: 9,9'-di-cis-zeta-carotene + a quinone <=> 7,9,9'-tri-cis-neurosporene + a quinol


name: G alpha (q) in G (q):RGS complex is inactivated (Caenorhabditis elegans)


name: 3-O-[N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + H(+) + UDP => L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: a 1-acyl-sn-glycero-3-phosphate + H(+) + L-serine => a 1-acyl-sn-glycero-3-phospho-L-serine + H2O


name: acetyl-CoA + S-benzyl-L-cysteine <=> CoA + H(+) + N-acetyl-S-benzyl-L-cysteine


name: a 2,3-saturated acyl-CoA + FAD + H(+) => a (2E)-enoyl-CoA + FADH2


name: 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+) => 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine


name: Formation of GINS complex (Mus musculus)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Homo sapiens)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)


name: FUT2 transfers Fuc to LeX to form LeY (Xenopus tropicalis)


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Sus scrofa)


name: menaquinol-7 + NAD(+) => H(+) + menaquinone-7 + NADH


name: ALK binds ligand pleiotrophin (PTN) (Sus scrofa)


name: PTGS2 dimer binds PTGS2 inhibitors (Bos taurus)


name: SRC family kinases phosphorylate ERBB2 (Mus musculus)


name: (2E,6E)-farnesyl diphosphate = african-1-ene + diphosphate


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Canis familiaris)


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Xenopus tropicalis)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Danio rerio)


name: L-aspartate(in) + L-glutamine(out) <=> L-aspartate(out) + L-glutamine(in)


name: (3R)-3-[(carboxymethyl)amino]butanoate + H(+) + holo-[ACP] => (2E)-butenoyl-[ACP] + glycine + H2O


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Rattus norvegicus)


name: [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + diphosphate => [glutamine synthetase]-L-tyrosine + ATP


name: glutaryl-CoA + O2 => (2E)-glutaconyl-CoA + H2O2


name: Proteasomal cleavage of substrate (Drosophila melanogaster)


name: (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NAD(+) => 4-methylsulfanyl-2-oxobutanoate + H(+) + NADH


name: (2E,6E)-farnesyl diphosphate + 4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one <=> 4-hydroxy-3-[(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-2-one + diphosphate


name: dimethylallyl diphosphate + H2O + yaequinolone E => [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Sus scrofa)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Gallus gallus)


name: Ub-RibC-AXIN is degraded by the proteasome (Rattus norvegicus)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = erythrodiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + NADPH + perillate => H2O + NADP(+) + perillyl aldehyde


name: ANGPTL4 binds to CDH11v (Xenopus tropicalis)


name: GIT1 binds bPIX (Caenorhabditis elegans)


name: Loss of Rrn3 from RNA Polymerase I promoter escape complex (Bos taurus)


name: an alpha-(gamma-L-glutamyl)-L-amino acid = 5-oxo-L-proline + an L-alpha-amino acid


name: L-aspartate + O2 = H2O2 + iminosuccinate


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Drosophila melanogaster)


name: ATP + benzoate + H(+) <=> benzoyl-AMP + diphosphate


name: TPX2 promotes AURKA autophosphorylation (Xenopus tropicalis)


name: SLC22A18 exchanges extracellular organic cations for cytosolic H+ (Danio rerio)


name: 2 H2O + L-dehydroascorbate => H2O2 + L-ascorbate


name: beta-cryptoxanthin + O2 => (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal


name: 3'-phosphoadenylyl sulfate + UDP-N-acetyl-alpha-D-galactosamine 4-sulfate <=> adenosine 3',5'-bisphosphate + H(+) + UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Dictyostelium discoideum)


name: 2 glutathione + H(+) + methylarsonate => glutathione disulfide + H2O + methylarsonous acid


name: L-rhamnopyranose + quercetin => H2O + quercitrin


name: PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: Activated FGFR3 binds SHC1 (Mus musculus)


name: 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O => (9Z)-octadecenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+)


name: N-hydroxy-L-isoleucine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-isoleucine + oxidized [NADPH--hemoprotein reductase]


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Bos taurus)


name: H2O + N-formimidoyl-L-glutamate <=> formamide + L-glutamate


name: SYK binds to p-Y65,Y76-FCER1G (Bos taurus)


name: hyocholate + UDP-alpha-D-glucuronate => H(+) + hyocholate 6-O-(beta-D-glucuronate) + UDP


name: FSTL3 binds Activin (Xenopus tropicalis)


name: 2 a phenolic radical donor + 2 H2O => 2 a phenolic donor + H2O2


name: (3S)-hydroxy-(9Z-octadecenoyl)-CoA => (2E,9Z)-octadecadienoyl-CoA + H2O


name: 3,3',5-triiodo-L-thyronine(out) + L-tyrosine(in) <=> 3,3',5-triiodo-L-thyronine(in) + L-tyrosine(out)


name: L-arabinose transmembrane transporter activity


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Bos taurus)


name: a 16alpha-hydroxysteroid <=> a 16beta-hydroxysteroid


name: norcoclaurine + S-adenosyl-L-methionine <=> coclaurine + H(+) + S-adenosyl-L-homocysteine


name: POM121 binds the Nup107-Nup160 complex (Drosophila melanogaster)


name: (E)-caffeate + H(+) + pyruvate => (E)-caffeoylpyruvate + H2O


name: D-glyceraldehyde 3-phosphate + glycolaldehyde => D-arabinose 5-phosphate


name: Dual mechanism MAPK inhibitors bind MAPKs (Mus musculus)


name: CK2:FACT phosphorylates TP53 (Homo sapiens)


name: PDK1 phosphorylates PKC (Schizosaccharomyces pombe)


name: N(6)-(1,2-dicarboxyethyl)-AMP => AMP + fumarate


name: PGLYRP2 binds bacterial peptidoglycan (Mus musculus)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Homo sapiens)


name: B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda (Rattus norvegicus)


name: (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + NADP(+)


name: (R)-3-amino-2-methylpropanoate + pyruvate <=> 2-methyl-3-oxopropanoate + L-alanine


name: tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent


name: arginine + H2O => ornithine + urea [ARG2] (Saccharomyces cerevisiae)


name: Autocatalytic activation of MMP7 (Xenopus tropicalis)


name: L-xylulose 5-phosphate => L-ribulose 5-phosphate


name: ATP + N-acetyl-alpha-D-galactosamine => ADP + H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate


name: (2E)-geranyl diphosphate => (1R,5R)-beta-pinene + diphosphate


name: acetyl-CoA + L-tryptophan + malonyl-CoA <=> CO2 + 2 CoA + cyclo-acetoacetyl-L-tryptophan + H2O


name: a 2-acylglycerol + ATP => a 2-acyl-sn-glycerol 3-phosphate + ADP + H(+)


name: ATP + CoA + OPC-6 => AMP + diphosphate + OPC-6-CoA


name: pyruvate oxidase (CoA-acetylating) activity


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Mus musculus)


name: 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + 2 H(+) => biphenyl-2,2',3-triol + O2


name: ERBB4s80:STAT5A complex translocates to the nucleus (Danio rerio)


name: an N-acylsphing-4-enine + D-galactose => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O


name: 2 cob(II)alamin-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] => 2 cob(I)alamin-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein]


name: H2O + tetracenomycin F1 => H(+) + tetracenomycin F2


name: biliverdin IXalpha + H(+) + NADH => bilirubin IXalpha + NAD(+)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Saccharomyces cerevisiae)


name: [Glu(-Cys)](n)-Gly + glutathione + H(+) <=> [Glu(-Cys)](n+1)-Gly + glycine


name: CD28 homodimer binds B7-2 monomer (Bos taurus)


name: 3-oxosphinganine + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoyl-3-oxosphinganine


name: Basigin interacts with CD43 (Sus scrofa)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Drosophila melanogaster)


name: (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(in) + ATP + H2O <=> (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(out) + ADP + H(+) + phosphate


name: Formation of pre-mRNPs (Plasmodium falciparum)


name: ACBD4,5 bind MCFA-CoA and LCFA-CoA (Plasmodium falciparum)


name: (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate + pyruvate => (2S)-2-amino-4-deoxychorismate + H2O


name: ITP(out) + UTP(in) <=> ITP(in) + UTP(out)


name: Exchange of oxygen with sulfur in MoCo (Drosophila melanogaster)


name: [(1->4)-beta-D-glucosyl](n) + GDP-alpha-D-glucose => [(1->4)-beta-D-glucosyl](n+1) + GDP + H(+)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Gallus gallus)


name: (2E,4E)-2,5-dichloromuconate + H(+) => 3,6-dichlorocatechol + O2


name: a 5-methyluridine in mRNA + H(+) + S-adenosyl-L-homocysteine => a uridine in mRNA + S-adenosyl-L-methionine


name: TPMT transfers CH3 from AdoMet to 6MP (Xenopus tropicalis)


name: 2-acetamidofluorene + H2O + NAD(+) = H(+) + N-hydroxy-2-acetamidofluorene + NADH


name: 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate => 3-O-(beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: Activated NOD2 oligomerizes (Homo sapiens)


name: 17alpha-hydroxypregnenolone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + pregnenolone + reduced [NADPH--hemoprotein reductase]


name: H2O + N(pros)-phospho-L-histidyl-[protein] = L-histidyl-[protein] + phosphate


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Homo sapiens)


name: 11-deoxycortisol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 18-hydroxy-11-deoxycortisol + H2O + 2 oxidized [adrenodoxin]


name: CTP(out) + dCTP(in) = CTP(in) + dCTP(out)


name: androst-5-en-3beta,17beta-diol + NAD(+) = 3beta-hydroxyandrost-5-en-17-one + H(+) + NADH


name: Activated protein C is released from PROCR (Gallus gallus)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Rattus norvegicus)


name: factor VII -> factor VIIa (Rattus norvegicus)


name: L-arginine + L-lysine => L-homoarginine + L-ornithine


name: (2S)-2-hydroxypentanenitrile => butanal + hydrogen cyanide


name: (3R)-hydroxyhexanoyl-[ACP] => (2E)-hexenoyl-[ACP] + H2O


name: acetate + ATP + H(+) <=> acetyl-AMP + diphosphate


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Sus scrofa)


name: (3R)-hydroxydocosanoyl-CoA + NADP(+) => 3-oxodocosanoyl-CoA + H(+) + NADPH


name: p-T774-PKN1 binds CDC25C (Dictyostelium discoideum)


name: ADP + H(+) + L-homocarnosine + phosphate => 4-aminobutanoate + ATP + L-histidine


name: ATP + N-hexadecanoylsphing-4-enine => ADP + H(+) + N-(hexadecanoyl)-sphing-4-enine-1-phosphate


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Drosophila melanogaster)


name: AH2 + O2 + preaustinoid A => A + H2O + preaustinoid A1


name: Association of procollagen type XXI (Canis familiaris)


name: RUNX2 binds SMAD1 in the nucleus (Homo sapiens)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Drosophila melanogaster)


name: 1D-myo-inositol 1,2-bisphosphate + H2O => 1D-myo-inositol 2-phosphate + phosphate


name: GSDME variant does not bind PIPs (Homo sapiens)


name: TFAP2C translocates to the nucleus (Homo sapiens)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Sus scrofa)


name: 3-oxoisoapionate + H(+) <=> CO2 + L-erythrulose


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Drosophila melanogaster)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + lydicene


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Canis familiaris)


name: H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate <=> L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate


name: ITCH binds DTX (Drosophila melanogaster)


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Homo sapiens)


name: Release of E3 from polyubiquitinated substrate (Canis familiaris)


name: an aldehyde + H(+) + NADPH => a primary alcohol + NADP(+)


name: beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)


name: Beta-catenin migrates to the nucleus (Caenorhabditis elegans)


name: 3-dehydro-6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 3-dehydroteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Gallus gallus)


name: The bound receptor dimerizes (Mus musculus)


name: Palmostatin B binds RAS depalmitoylases (Canis familiaris)


name: 3-oxoeicosanoyl-CoA + H(+) + NADPH <=> (3R)-hydroxyeicosanoyl-CoA + NADP(+)


name: SEMA4D interacts with CD72 (Homo sapiens)


name: an N-(fatty acyl)-L-methionine + H2O = a fatty acid + L-methionine


name: Activated FGFR4 phosphorylates PPTN11 (Bos taurus)


name: 2 H2O + 4 monodehydro-L-ascorbate radical => 4 L-ascorbate + O2


name: an N-fatty acyl-taurine + CoA + H(+) => a fatty acyl-CoA + taurine


name: ERBB2 KD mutants bind trastuzumab (Homo sapiens)


name: NAD-dependent histone decrotonylase activity


name: A + L-pipecolate = AH2 + H(+) + L-1-piperideine-6-carboxylate


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Dictyostelium discoideum)


name: 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: SFTPB binds itself (Drosophila melanogaster)


name: H2O + N-terminal N(alpha)-acetyl-L-cysteinyl-L-glutamyl-[protein] <=> N-acetyl-L-cysteine + N-terminal L-glutamyl-[protein]


name: Cdh1:APC/C complex binds EHMT1:EHMT2 (Homo sapiens)


name: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH


name: CD28 homodimer binds B7-1 homodimer (Mus musculus)


name: acetyl-CoA + malonate <=> acetate + malonyl-CoA


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Canis familiaris)


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Sus scrofa)


name: a long-chain primary fatty alcohol + H2O + 2 NAD(+) = a long-chain fatty acid + 3 H(+) + 2 NADH


name: PIAS4 SUMOylates TOP2A with SUMO2,3 (Gallus gallus)


name: COX15 transforms heme O to heme A (Saccharomyces cerevisiae)


name: 1-(7Z,10Z,13Z,16Z-docosatetraenoyl)-glycerol + H2O => (7Z,10Z,13Z,16Z)-docosatetraenoate + glycerol + H(+)


name: CoA + H(+) + N-hexacosanoylglycine => glycine + hexacosanoyl-CoA


name: 2-hydroxydodecanoate + H2O2 => 2,3-dihydroxydodecanoate + H2O


name: an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine <=> an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine


name: dihydrochelirubine + NAD(+) <=> chelirubine + NADH


name: SLC29A1 transports RBV from cytosol to extracellular region (Drosophila melanogaster)


name: 2 L-arginine + 4 O2 + 3 reduced [flavodoxin] <=> 5 H(+) + 4 H2O + 2 L-citrulline + 2 nitric oxide + 3 oxidized [flavodoxin]


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Sus scrofa)


name: H(+)(out) + L-alanyl-L-lysine(out) = H(+)(in) + L-alanyl-L-lysine(in)


name: G-protein alpha subunit is inactivated (Caenorhabditis elegans)


name: 15-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate => (8Z,11Z,14Z)-eicosatrienoate + O2


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Sus scrofa)


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)


name: Interaction of E3 ligase with ISG15:E2 complex (Mus musculus)


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Caenorhabditis elegans)


name: Endosome acidification (Dictyostelium discoideum)


name: H(+) + N,N-dihydroxy-L-dihomomethionine = (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O


name: ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Mus musculus)


name: H2O + N-eicosanoyl-sphing-4-enine <=> eicosanoate + sphing-4-enine


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate = (-)-germacrene D + diphosphate


name: 7,8-dihydrofolate + ADP + H(+) + phosphate => 7,8-dihydropteroate + ATP + L-glutamate


name: Formation of the Spliceosomal P complex and exon ligation (Sus scrofa)


name: 3,6-anhydro-L-galactonate + 2 H(+) + NADH => 3,6-anhydro-alpha-L-galactopyranose + H2O + NAD(+)


name: PC is hydrolyzed to 2-acyl LPC by PLA2G4C (Saccharomyces cerevisiae)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Rattus norvegicus)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Mus musculus)


name: GDIs block activation of RHOA (Danio rerio)


name: a carotenoid psi-end group => a carotenoid epsilon-end group


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Caenorhabditis elegans)


name: prostaglandin E1(out) <=> prostaglandin E1(in)


name: ADP + H(+) + L-alanyl-L-histidine(in) + phosphate => ATP + H2O + L-alanyl-L-histidine(out)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GM1alpha (d18:1(4E)) + CMP + H(+)


name: dehydroepiandrosterone 3-sulfate(out) + succinate(in) => dehydroepiandrosterone 3-sulfate(in) + succinate(out)


name: low-density lipoprotein particle receptor activity


name: 3 H(+) + NADPH + O2 + 2 rubrofusarin B <=> 2 H2O + NADP(+) + nigerone


name: RNA polymerase I general transcription initiation factor activity


name: lipoate transmembrane transporter activity


name: [protein]-disulfide + H2O2 => [protein]-dithiol + O2


name: A + Fe(II)-heme i + H2O <=> AH2 + Fe(II)-hydroxyheme i


name: Separation of elongating transcript from template (Bos taurus)


name: racemase and epimerase activity, acting on carbohydrates and derivatives


name: LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Sus scrofa)


name: D-tryptophan + O2 <=> N-formyl-D-kynurenine


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Caenorhabditis elegans)


name: SPHK2 binds SPHK2 inhibitors (Canis familiaris)


name: (1R)-(2-amino-1-hydroxyethyl)phosphonate = NH4(+) + phosphonoacetaldehyde


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Mus musculus)


name: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Danio rerio)


name: A + H2O + quinolin-5-ol => 5-hydroxyquinolin-2(1H)-one + AH2


name: 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: H2O + N(4)-acetylcytosine = acetate + cytosine + H(+)


name: Elastin degradation by MMP14 (Mus musculus)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Dictyostelium discoideum)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Rattus norvegicus)


name: RAPGEF1 activates RAP1 (Rattus norvegicus)


name: PDGF binds to extracellular matrix proteins (Homo sapiens)


name: ATP + Fe(III)-enterobactin(out) + H2O => ADP + Fe(III)-enterobactin(in) + H(+) + phosphate


name: PSAP(195-273) forms a dimer (Rattus norvegicus)


name: LC3:ATG7 dimer binds ATG3 (Canis familiaris)


name: The PIDDosome activates CASP2 (Rattus norvegicus)


name: H(+)(out) + L-proline(out) = H(+)(in) + L-proline(in)


name: hydrogencarbonate + NH4(+) <=> carbamate + H(+) + H2O


name: BH2 binding can lead to eNOS uncoupling (Dictyostelium discoideum)


name: H(+) + L-dopa + NADH <=> 3-(3,4-dihydroxyphenyl)propanoate + NAD(+) + NH4(+)


name: Constitutive phosphorylation of kinase domain KIT mutants (Homo sapiens)


name: H(+)(out) + L-proline(out) <=> H(+)(in) + L-proline(in)


name: Active ALK phosphorylates SHC1 (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR2b (Drosophila melanogaster)


name: AMP + diphosphate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => (R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein]


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: LIPC dimer hydrolyses TAG to DAG and FA (Rattus norvegicus)


name: 2-oxoglutarate + cadaverine = 5-aminopentanal + L-glutamate


name: 4-amino-3-all-trans-hexaprenylbenzoate + diphosphate => 4-aminobenzoate + all-trans-hexaprenyl diphosphate


name: N-formimidoyl-L-glutamate => 4-imidazolone-5-propanoate + H2O


name: lithocholoyl-CoA + NAD(+) <=> 3-oxocholan-24-oyl-CoA + H(+) + NADH


name: ER calcium channels open in response to activated PKA (Canis familiaris)


name: H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine


name: 1-O-alkyl-sn-glycero-3-phosphate + an acyl-CoA = 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + CoA


name: 40 ATP + 40 H2O + N2 + 12 reduced [2Fe-2S]-[ferredoxin] => 40 ADP + 26 H(+) + 3 H2 + 2 NH4(+) + 12 oxidized [2Fe-2S]-[ferredoxin] + 40 phosphate


name: NADP(+) + octanal <=> (2E)-octenal + H(+) + NADPH


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: Formation of Okazaki fragments (Dictyostelium discoideum)


name: CPT1A,B transfers PALM to CAR (Canis familiaris)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Homo sapiens)


name: L-tyrosyl-[protein] + 2 O2 <=> H(+) + H2O2 + L-topaquinyl-[protein]


name: Collagen type II binds integrin alpha2beta1, alpha1beta1, alpha11beta1 (Homo sapiens)


name: Release of mature NEDD8 (Schizosaccharomyces pombe)


name: CYP3A4, CYP2B6 bind ritonavir (Rattus norvegicus)


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Danio rerio)


name: p-PKR dimer phosphorylates SNCA (Gallus gallus)


name: ALK binds ligand pleiotrophin (PTN) (Homo sapiens)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Homo sapiens)


name: B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac (Mus musculus)


name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Drosophila melanogaster)


name: glycine + H2O + NAD(+) = glyoxylate + H(+) + NADH + NH4(+)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Danio rerio)


name: coenzyme M + methyl-Co(III)-[glycine betaine-specific corrinoid protein] = Co(I)-[glycine betaine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: "[methyl-Co(III) glycine betaine-specific corrinoid protein]--coenzyme M methyltransferase"


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Caenorhabditis elegans)


name: RHOF GAPs stimulate RHOF GTPase activity (Schizosaccharomyces pombe)


name: ADP + H(+) + N-[(S)-lactoyl]-L-phenylalanine(out) + phosphate => ATP + H2O + N-[(S)-lactoyl]-L-phenylalanine(in)


name: ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA (Dictyostelium discoideum)


name: PTP1B binds the GH receptor complex (Rattus norvegicus)


name: H(+)(in) + L-tyrosine(in) <=> H(+)(out) + L-tyrosine(out)


name: PPA2A dephosphorylates SPRY2 (Rattus norvegicus)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Homo sapiens)


name: FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + cholesterol = 1-hexadecanoyl-sn-glycero-3-phosphocholine + a cholesterol ester


name: (2E)-decenoyl-CoA + NADP(+) => (2E,4E)-decadienoyl-CoA + H(+) + NADPH


name: DCAKD phosphorylates DP-CoA (Caenorhabditis elegans)


name: Cinaciguat binds sGC:NO (Drosophila melanogaster)


name: Interleukin-5 is a homodimer (Canis familiaris)


name: Phenol can form a sulfate conjugate (Rattus norvegicus)


name: cis-4-coumarate + UDP-alpha-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP


name: an aromatic aldehyde + H2O + NAD(+) <=> an aromatic carboxylate + 2 H(+) + NADH


name: Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)


name: HMG CoA => acetoacetic acid + acetyl CoA (Danio rerio)


name: acetyl-CoA + octanoyl-CoA = 3-oxodecanoyl-CoA + CoA


name: ALDH2 transforms GTN to NO (Xenopus tropicalis)


name: Caspase cleavage of UNC5B (Homo sapiens)


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Bos taurus)


name: 2 H(+) + O2 + pentalenolactone F + 2 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalenolactone


name: (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-glycerol + H(+) => 1,2-di-(9Z-octadecenoyl)-glycerol + H2O


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Caenorhabditis elegans)


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Bos taurus)


name: ABCC5 transports TPMP substrates from cytosol to extracellular region (Gallus gallus)


name: 2-oxoglutarate + H2O2 + NH4(+) => D-glutamate + H2O + O2


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: Formation of CRY:PER:Kinase complex (Homo sapiens)


name: CDK1 phosphorylates LPIN (Xenopus tropicalis)


name: GGA3 associates with activated MET receptor (Bos taurus)


name: tetX LC cleaves target cell VAMP2 (Homo sapiens)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Plasmodium falciparum)


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Rattus norvegicus)


name: dehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) = dehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: Keratin filaments bind cell-cell adhesion complexes (Sus scrofa)


name: adenosine 3',5'-bisphosphate + alpha-muricholate 7-sulfate + H(+) => 3'-phosphoadenylyl sulfate + alpha-muricholate


name: α2-agonists bind ADRA2A,B,C (Gallus gallus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 => A + H2O + prostaglandin H2


name: Formation of the 'destruction complex' (Drosophila melanogaster)


name: TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4  (Homo sapiens)


name: CK2:FACT phosphorylates TP53 (Sus scrofa)


name: Ligand-independent dimerization of overexpressed FGFR1b (Homo sapiens)


name: IL10 dimer binds IL10RA:JAK1 (Danio rerio)


name: (E,E)-piperoyl-AMP + diphosphate => (E,E)-piperate + ATP + H(+)


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Sus scrofa)


name: H2O + sucrose 6(F)-phosphate => beta-D-fructose + beta-D-glucose 6-phosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-octadecyl-sn-glycero-3-phosphocholine = 1-O-octadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) + ATP


name: Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Canis familiaris)


name: dGMP + inosine <=> 2'-deoxyguanosine + IMP


name: beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Sus scrofa)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Saccharomyces cerevisiae)


name: H(+) + NAD(+) + 2 reduced [nitric oxide reductase rubredoxin domain] = NADH + 2 oxidized [nitric oxide reductase rubredoxin domain]


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Mus musculus)


name: NFE2L2-dependent TKT gene expression (Homo sapiens)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Rattus norvegicus)


name: N-(5-phospho-beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate


name: Deubiquitination of RNF41 by P-USP8 (Rattus norvegicus)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Bos taurus)


name: 3-oxo-(7Z-hexadecenoyl)-CoA + CoA = (5Z)-tetradecenoyl-CoA + acetyl-CoA


name: POLZ extends translesion synthesis (Xenopus tropicalis)


name: L-lysyl-[lipoyl-carrier protein] + N(6)-octanoyl-L-lysyl-[glycine-cleavage complex H protein] = L-lysyl-[glycine-cleavage complex H protein] + N(6)-octanoyl-L-lysyl-[lipoyl-carrier protein]


name: Formation of the 43S pre-initiation complex (Schizosaccharomyces pombe)


name: SOAT1,2 transfer acyl group to CHOL forming CHEST (Drosophila melanogaster)


name: H2O + N(alpha)-acetyl-L-methionine <=> acetate + L-methionine


name: 1-deoxymethyl-3-dehydrosphinganine + H(+) + NADPH => 1-deoxymethyl-sphinganine + NADP(+)


name: Caspase-mediated cleavage of GAS2 (Canis familiaris)


name: PGRMC2:Hemes translocate to the nucleus (Sus scrofa)


name: Caspase-mediated cleavage of Etk (Homo sapiens)


name: 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NAD(+) => 3-dehydro-4alpha-methylzymosterol + CO2 + NADH


name: 11-dehydrocorticosterone + NAD(+) => H(+) + NADH + pregn-4-ene-3,11,20,21-tetraone


name: 2 ATP = adenosine 3'-diphosphate,5'-triphosphate + AMP


name: malvidin + UDP-alpha-D-galactose => H(+) + malvidin 3-O-beta-D-galactoside + UDP


name: TPI1 isomerizes GA3P to DHAP (Plasmodium falciparum)


name: mRNA1 is translated to pp1ab (Homo sapiens)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Gallus gallus)


name: SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Bos taurus)


name: dihydroneopterin triphosphate pyrophosphohydrolase activity


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Xenopus tropicalis)


name: Activation of Rap1 by membrane-associated GEFs (Gallus gallus)


name: 2 alpha-D-glucose 1-phosphate + H2O = D-maltose + 2 phosphate


name: digoxigenin + 2 Fe(II)-[cytochrome c] + 3 H(+) => dihydrodigoxigenin + 2 Fe(III)-[cytochrome c]


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)


name: a menaquinol(in) + dimethyl sulfoxide(out) = a menaquinone(in) + dimethyl sulfide(out) + H2O(out)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Schizosaccharomyces pombe)


name: CoA + H(+) + N-acetyl-L-methionine sulfone => acetyl-CoA + L-methionine sulfone


name: USP18 deubiquitinates TAK1:TAB1 (Rattus norvegicus)


name: an adenosine in tRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oryzalexin E + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: Activation of GRIK3 homomer (Canis familiaris)


name: H2O + N(1)-aminopropylagmatine => spermidine + urea


name: Relaxin receptor 1 binds relaxin 2 and 3 (Xenopus tropicalis)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Dictyostelium discoideum)


name: Phosphorylation of Syntaxin-4 (Caenorhabditis elegans)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine + a cardiolipin


name: SUMOylation of Histone H4 with SUMO3 (Mus musculus)


name: Recruitment of CBL to KIT (Drosophila melanogaster)


name: 2 (2E,6E)-farnesyl diphosphate + H(+) + NADH <=> 2 diphosphate + NAD(+) + squalene


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Canis familiaris)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus (Mus musculus)


name: glyoxylate + N(omega)-methyl-L-arginine <=> 5-(3-methylguanidino)-2-oxopentanoate + glycine


name: Basigin homodimerises (Drosophila melanogaster)


name: H2O + propanoyl-CoA = CoA + H(+) + propanoate


name: 3-hydroxycyclohexanone + A = AH2 + cyclohexane-1,3-dione


name: Activation of Rap1 by cytosolic GEFs (Xenopus tropicalis)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Drosophila melanogaster)


name: Phosphorylated Cdc6 is exported from the nucleus (Caenorhabditis elegans)


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Bos taurus)


name: 4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD(+)


name: CYSLT2 binds LTC4,LTD4,LTE4 (Danio rerio)


name: L-arginine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) => L-arginine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: 5-phospho-beta-D-ribosylamine + ATP + glycine <=> ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate


name: ethanol + NAD(+) <=> acetaldehyde + H(+) + NADH


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Bos taurus)


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Mus musculus)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Gallus gallus)


name: Formation of the MLL2 complex (Rattus norvegicus)


name: GSTO dimers reduce DeHA to AscH- (Canis familiaris)


name: Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine] + N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine => Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + H(+) + H2O


name: CTP + H(+) + sn-glycerol 3-phosphate = CDP-glycerol + diphosphate


name: Formation of Cyclin E:Cdk2 complexes (Mus musculus)


name: glycine transmembrane transporter activity


name: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-hedycaryol + diphosphate


name: thyroid hormone transmembrane transporter activity


name: cholesteryl 3-beta-D-glucoside + H2O = cholesterol + D-glucose


name: L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Gallus gallus)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] = 1,10-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H(+) + NADPH = (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + NADP(+)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Sus scrofa)


name: beta-D-fructose 1-phosphate + H2O => D-fructose + phosphate


name: H2O + sphinganine 1-phosphate = phosphate + sphinganine


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Rattus norvegicus)


name: Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA (Caenorhabditis elegans)


name: a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]


name: Autocatalytic phosphorylation of FGFR3b (Caenorhabditis elegans)


name: YWHAB dimer dissociates from dephosphorylated RAF (Caenorhabditis elegans)


name: Agmatine + H2O <=> putrescine + urea (Rattus norvegicus)


name: Exogenous soluble antigen targeted to more stable early endosome (Mus musculus)


name: SMAD7 binds to SMURF2 (Rattus norvegicus)


name: dehydroepiandrosterone 3-sulfate(in) + pentanoate(out) <=> dehydroepiandrosterone 3-sulfate(out) + pentanoate(in)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(4)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(4)-[histone H3] + succinate


name: a tetradecanoate ester + H2O <=> an aliphatic alcohol + H(+) + tetradecanoate


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Saccharomyces cerevisiae)


name: MRN complex bound to DNA ends recruits ATM (Canis familiaris)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Homo sapiens)


name: CX3 complex binds D-loop structures (Bos taurus)


name: atrochrysone carboxylate + H(+) = atrochrysone + CO2


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Xenopus tropicalis)


name: H2O + N(6)-acetyl-L-lysyl-[alpha-tubulin] => acetate + L-lysyl-[alpha-tubulin]


name: 5'-deoxyadenosine + H2O <=> 5-deoxy-D-ribose + adenine


name: (2R,3S)-3-isopropylmalate(in) + sulfate(out) = (2R,3S)-3-isopropylmalate(out) + sulfate(in)


name: BRAP autoubiquitinates (Canis familiaris)


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Mus musculus)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Danio rerio)


name: MME:Zn2+ binds sacubitrilat (Xenopus tropicalis)


name: Activation of Rho by LARG and PDZ-RhoGEF (Mus musculus)


name: malonyl-CoA + rhaponticin = 6-O-malonyl-rhaponticin + CoA


name: isocitrate <=> citrate (Drosophila melanogaster)


name: 14-3-3epsilon attentuates NADE-related apoptosis (Mus musculus)


name: IMPDH tetramers binds IMPDH inhibitors (Saccharomyces cerevisiae)


name: ADP + H(+) + K(+)(in) + phosphate => ATP + H2O + K(+)(out)


name: Activated NTRK2 recruits PI3K (Homo sapiens)


name: HCFC1, HCFC2 bind the MLL1:MEN1 complex (Gallus gallus)


name: NTPDase2 hydrolyzes nucleoside triphosphates (Sus scrofa)


name: 2-O-hexadecanoyl-alpha,alpha-trehalose + hexadecanoyl-CoA => 2-O,3-O-dihexadecanoyl-alpha,alpha-trehalose + CoA


name: p-4Y-PLCG1 dissociates from activated FGFR4 mutants (Homo sapiens)


name: Association of procollagen type XVII (Canis familiaris)


name: (2E)-geraniol + acetyl-CoA <=> (2E)-geranyl acetate + CoA


name: 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: PIP3 binds to RhoA and activates it (Xenopus tropicalis)


name: RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Mus musculus)


name: RFC dissociates after sliding clamp formation on the C-strand of the telomere (Canis familiaris)


name: 8-demethyl-8-(methylamino)riboflavin + S-adenosyl-L-methionine = H(+) + roseoflavin + S-adenosyl-L-homocysteine


name: all-trans-beta-carotene + O2 => all-trans-10'-apo-beta-carotenal + beta-ionone


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + octadecanoate <=> (R)-2-hydroxyoctadecanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: glyoxylate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: CTP(out) + UMP(in) <=> CTP(in) + UMP(out)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Saccharomyces cerevisiae)


name: Phosphorylation of IFNGR1 by JAK kinases (Bos taurus)


name: Formation of the CE:GMP intermediate complex (Dictyostelium discoideum)


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Plasmodium falciparum)


name: GP1BA variant binds to VWF multimer:collagen (Homo sapiens)


name: acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O (Rattus norvegicus)


name: a fatty acid + H(+) + long chain acyl-3-O-beta-D-galactosyl-sn-glycerol => H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol


name: (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+) => catechol + H(+) + NADPH


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Gallus gallus)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + AH2 + O2 => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + A + 2 H2O


name: Association of NS1 (1C) with Cul5 and SCF (Homo sapiens)


name: 3'-UMP + H(+) => 2',3'-cyclophospho-UMP + H2O


name: chloromethane + S-adenosyl-L-homocysteine => chloride + S-adenosyl-L-methionine


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Canis familiaris)


name: Binding of APOBEC-1 to form editosome (Sus scrofa)


name: UXT gene expression is repressed by the PRC1L4 complex (Homo sapiens)


name: Recruitment of VAV to p-SLP-76 (Sus scrofa)


name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Bos taurus)


name: IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN2B (GRIN2B) (Homo sapiens)


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Dictyostelium discoideum)


name: (S)-dihydroorotate + a quinone = a quinol + orotate


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Saccharomyces cerevisiae)


name: beta-alanyl-L-arginine + H2O <=> beta-alanine + L-arginine


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Homo sapiens)


name: Regeneration of eEF1A:GTP by eEF1B activity (Schizosaccharomyces pombe)


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Xenopus tropicalis)


name: EGFR phosphorylates NOTCH3 (Xenopus tropicalis)


name: 7alpha-hydroxycholesterol + NAD(+) = 7alpha-hydroxycholest-4-en-3-one + H(+) + NADH


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Bos taurus)


name: Activation of RAC1 by VAV2/3 (Xenopus tropicalis)


name: Elastin degradation by MMP14 (Bos taurus)


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Drosophila melanogaster)


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Gallus gallus)


name: guanosine(2270) in 21S rRNA + S-adenosyl-L-methionine => 2'-O-methylguanosine(2270) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine


name: UGCG transfers glucose to ceramide (Caenorhabditis elegans)


name: 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Canis familiaris)


name: (9Z)-octadecenoyl-CoA + di-(9Z)-octadecenoylglycerol => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA


name: Activation of RAC1 by the PXN:CRK complex (Drosophila melanogaster)


name: 2-methylpropan-1-amine + FADH2 + O2 = FAD + 2 H(+) + H2O + N-(2-methylpropyl)hydroxylamine


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: ALOX5 oxidises 15S-HpETE to LXA4/B4 (Homo sapiens)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate = terpentedienyl diphosphate


name: 2-oxoglutarate + cadaverine <=> 5-aminopentanal + L-glutamate


name: TP53 binds regulatory elements of SESN1,2,3 genes (Homo sapiens)


name: fumarate(in) + L-aspartate(out) = fumarate(out) + L-aspartate(in)


name: (9Z,12Z)-octadecadienoate + O2 = (9S)-hydroperoxy-(10E,12Z)-octadecadienoate


name: an N-(acyl)-sphingosylphosphocholine(in) <=> an N-(acyl)-sphingosylphosphocholine(out)


name: A + H2O + thymine => 5-methylbarbiturate + AH2 + H(+)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Sus scrofa)


name: a dicarboxylate(in) + estrone 3-sulfate(out) <=> a dicarboxylate(out) + estrone 3-sulfate(in)


name: Formation of cap binding complex (CBC) (Dictyostelium discoideum)


name: ADP + H(+) + phosphoethanolamine => ATP + ethanolamine


name: cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine <=> H(+) + N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine


name: HSD17B3-like proteins reducde ANDST to TEST (Plasmodium falciparum)


name: hexan-1-ol + NAD(+) = H(+) + hexanal + NADH


name: Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Mus musculus)


name: geranylgeranyl diphosphate = tuberculosinyl diphosphate


name: a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate => a ganglioside GD1a + CMP + H(+)


name: butan-1-ol + hexanoyl-CoA = butyl hexanoate + CoA


name: chloride(in) + glycine(in) + 2 Na(+)(in) => chloride(out) + glycine(out) + 2 Na(+)(out)


name: 20-oxo-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-acyl-15-methylhexadecasphing-4-enine <=> a 1,2-diacyl-sn-glycerol + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine


name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)


name: D-glyceraldehyde 3-phosphate + H2O + NADP(+) = (2R)-3-phosphoglycerate + 2 H(+) + NADPH


name: Degradation of multiubiquitinated Nek2A (Sus scrofa)


name: MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Plasmodium falciparum)


name: Translocation of ERBB4s80 to the nucleus (Homo sapiens)


name: OCT1 transports organic cations out of hepatic cells (Rattus norvegicus)


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Rattus norvegicus)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Plasmodium falciparum)


name: Dissociation of the COP1-p53 complex (Xenopus tropicalis)


name: CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Bos taurus)


name: IKBA is phosphorylated by Phospho IKKB kinase (Homo sapiens)


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Homo sapiens)


name: HSD17B13 binds lipid droplets (Rattus norvegicus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Schizosaccharomyces pombe)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Rattus norvegicus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: (22E)-3-oxochola-4,22-dien-24-oyl-CoA + H2O => (22R)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA


name: a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP


name: Fibronectin degradation by MMP14, TMPRSS6 (Bos taurus)


name: 5 (S)-methylmalonyl-CoA + 11 H(+) + malonyl-CoA + 5 NADPH => 10-deoxymethynolide + 6 CO2 + 6 CoA + 2 H2O + 5 NADP(+)


name: 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase => a purine 2'-deoxy-D-ribonucleoside + phosphate


name: (9Z)-tetradecenoyl-CoA + H2O <=> (9Z)-tetradecenoate + CoA + H(+)


name: G alpha (z) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 bromide + 3 FADH2 + 3 O2 = (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 FAD + 6 H2O


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Gallus gallus)


name: Receptor CXCR6 binds CXCL16 ligand (Sus scrofa)


name: an acyl phosphate + sn-glycerol 3-phosphate <=> a 1-acyl-sn-glycero-3-phosphate + phosphate


name: Formation of the pre-incision complex in GG-NER (Sus scrofa)


name: p-PKR dimer phosphorylates MKK6 (Sus scrofa)


name: NT5C2 tetramer dephosphorylates RBV-MP (Rattus norvegicus)


name: Kinesin-2 is a heterotrimer (Homo sapiens)


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Bos taurus)


name: H2O + L-alanyl-L-aspartate = L-alanine + L-aspartate


name: 2-oxoglutarate + hexadecanoyl-CoA + O2 => 2-hydroxyhexadecanoyl-CoA + CO2 + succinate


name: Formation of a heteromeric BMP receptor complex (Xenopus tropicalis)


name: [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + H2O => (9Z)-hexadecenoate + [Wnt protein]-L-serine + H(+)


name: Joining of adjacent Okazaki fragments of the C-strand (Canis familiaris)


name: (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: (13R)-manoyl oxide + diphosphate => 8-hydroxycopalyl diphosphate


name: H2O + NAD(+) + spermine monoaldehyde = 2 H(+) + N-(2-carboxyethyl)spermidine + NADH


name: 2 2-aminophenol + A + O2 => 2-aminophenoxazin-3-one + AH2 + 2 H2O


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Danio rerio)


name: malonyl-malonyl acyl carrier protein-condensing enzyme activity


name: PTPN7 dephosphorylates p-T,Y-MAPKs (Homo sapiens)


name: 4-(dimethylamino)azobenzene + H2O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH


name: RFC binding displaces Pol Alpha on the C-strand of the telomere (Sus scrofa)


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Xenopus tropicalis)


name: ADH5 oxidises S-HMGSH to S-FGSH (Danio rerio)


name: AVPR1A,B bind desmopressin (Gallus gallus)


name: 3-oxopentanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxypentanoyl-[ACP] + NADP(+)


name: H2O + O2 + S-sulfanylglutathione = glutathione + 2 H(+) + sulfite


name: pyrimidine-specific mismatch base pair DNA N-glycosylase activity


name: 3 H2O + hydrogen sulfide + 3 NADP(+) => 4 H(+) + 3 NADPH + sulfite


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Bos taurus)


name: Active PLC-gamma1 dissociates from EGFR (Gallus gallus)


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Sus scrofa)


name: ATP + L-arginine + L-tyrosine => AMP + diphosphate + H(+) + L-tyrosyl-L-arginine


name: MAPKAPK2 phosphorylates HSF1 (Caenorhabditis elegans)


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Danio rerio)


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-dGTP = dGTP + glycolate + H(+)


name: EPHB phosphorylates TIAM1 (Mus musculus)


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Mus musculus)


name: 6 (S)-methylmalonyl-CoA + 12 H(+) + 6 NADPH + propanoyl-CoA <=> 6-deoxyerythronolide B + 6 CO2 + 7 CoA + H2O + 6 NADP(+)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) = 5,7-dihydroxy-4-methylphthalide + H2O


name: ADP + beta-D-fructose 6-phosphate <=> AMP + beta-D-fructose 1,6-bisphosphate + H(+)


name: ESR1:ESTG bind the EBAG9 5' region (Homo sapiens)


name: ATP + CoA + tetradecanoate <=> AMP + diphosphate + tetradecanoyl-CoA


name: SH3PXD2A binds ADAM12,ADAM15,ADAM19 (Homo sapiens)


name: Nectin-2:Nectin 3 trans heterodimer interaction (Mus musculus)


name: 22-hydroxydocosanoate + NAD(+) <=> 22-oxodocosanoate + H(+) + NADH


name: 16beta,17beta-estriol + UDP-alpha-D-glucuronate => 16beta,17beta-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: C1-Inh binds and inactivates C1r, C1s (Canis familiaris)


name: MMACHC decyanates CNCbl (Canis familiaris)


name: 1D-myo-inositol 1-phosphate + glycerol + H(+) => H2O + sn-glycero-3-phospho-1D-myo-inositol


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O


name: Association of Emi1 with Cdh1 (Danio rerio)


name: SUMOylation of Histone H4 with SUMO3 (Gallus gallus)


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Sus scrofa)


name: FA anion diffuses laterally to UCP (Drosophila melanogaster)


name: Viral DNA cleavage by TREX1 (Homo sapiens)


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Canis familiaris)


name: N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-methionine <=> H(+) + hercynine + S-adenosyl-L-homocysteine


name: (1S,2R)-ephedrine + NAD(+) = (R)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Drosophila melanogaster)


name: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose => 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose + H(+)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Canis familiaris)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Canis familiaris)


name: (S)-reticuline + H(+) + S-adenosyl-L-homocysteine => (S)-3'-hydroxy-N-methylcoclaurine + S-adenosyl-L-methionine


name: (4S)-5,6-dihydro-4H-1,3-thiazine-4-carboxylate + 2 H(+) + NADH + NH4(+) => NAD(+) + S-(2-aminoethyl)-L-cysteine


name: camphor + H(+) + NADH => borneol + NAD(+)


name: beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + cholesterol <=> cholesteryl 3-beta-D-xyloside + N-(9Z-octadecenoyl)-sphing-4-enine


name: p-T182 MAPKAPK5 phosphorylates FOXO3 (Danio rerio)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Gallus gallus)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Danio rerio)


name: PIAS1 SUMOylates SP3 with SUMO1 (Saccharomyces cerevisiae)


name: NMUR2 binds neuromedin-S (Gallus gallus)


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Xenopus tropicalis)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Mus musculus)


name: 1,4-dihydroxy-2-naphthoate + all-trans-dodecaprenyl diphosphate + H(+) = 2-demethylmenaquinol-12 + CO2 + diphosphate


name: betaine aldehyde + H2O + NAD(+) <=> glycine betaine + 2 H(+) + NADH


name: L-cysteinyl-[protein] + tetradecanoyl-CoA => CoA + S-tetradecanoyl-L-cysteinyl-[protein]


name: Phosphorylation of STAT1 at Ser727 (Mus musculus)


name: SARS-CoV-1 nsp1 binds to PPIase (Homo sapiens)


name: ABCB1 transports xenobiotics out of the cell (Schizosaccharomyces pombe)


name: a thymidine(6-4)cytidine in DNA => a thymine-cytidine dinucleotide in DNA


name: (20S)-protopanaxadiol + UDP-alpha-D-glucose = (20S)-ginsenoside C-K + H(+) + UDP


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Bos taurus)


name: RUNX2 and RB1 bind the COL1A1 gene promoter (Homo sapiens)


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Dictyostelium discoideum)


name: PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)


name: p-hydroxyphenylpyruvate + O2 => homogentisate + CO2 (Mus musculus)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Xenopus tropicalis)


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Xenopus tropicalis)


name: 6-trans-leukotriene B4 + NADP(+) => 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + H(+) + NADPH


name: 5-hydroxyxanthotoxin + S-adenosyl-L-methionine = isopimpinellin + S-adenosyl-L-homocysteine


name: D-tryptophanyl-tRNA(Trp) + H2O <=> D-tryptophan + tRNA(Trp)


name: SLC6A4 binds TCAs and SSRIs (Gallus gallus)


name: 5-HT2 receptor can bind serotonin (Xenopus tropicalis)


name: H(+) + NADPH + O2 + urate => 5-hydroxyisourate + H2O + NADP(+)


name: CTP(in) + dCDP(out) => CTP(out) + dCDP(in)


name: 3alpha-sulfodeoxycholate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + deoxycholate


name: Exocytosis of tertiary granule membrane proteins (Dictyostelium discoideum)


name: Formation of ORC(1-5) complex (Schizosaccharomyces pombe)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Homo sapiens)


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Danio rerio)


name: PGRMC2:Hemes translocate to the nucleus (Gallus gallus)


name: adenosine + H(+) + tuberculosinyl diphosphate => 1-tuberculosinyladenosine + diphosphate


name: GOT2 transaminates oxaloacetate and glutamate (Bos taurus)


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Homo sapiens)


name: Activation of proMMP7 by MMP3 (Danio rerio)


name: PXLP-K56-SRR dimer deaminates L-Ser (Xenopus tropicalis)


name: an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: PDCL releases folded G-beta from TRiC/CCT (Rattus norvegicus)


name: UBF-1 Binds rDNA Promoter (Homo sapiens)


name: Phospholipase C-gamma1 binds to the activated EGF receptor (Bos taurus)


name: 2 H2O + L-1-piperideine-6-carboxylate + NADP(+) <=> H(+) + L-2-aminoadipate + NADPH


name: TP63/TP53 bind the DDIT4 gene promoter (Homo sapiens)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Canis familiaris)


name: a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a 1,2-diacyl-sn-glycerol => 2 a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 O2 => prostaglandin G3


name: isoorientin + S-adenosyl-L-methionine = H(+) + isoscoparin + S-adenosyl-L-homocysteine


name: NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Schizosaccharomyces pombe)


name: PGH2 is isomerised to PGD2 by PTGDS (Rattus norvegicus)


name: Inactivation of Lck by Csk (Mus musculus)


name: (9Z,12Z)-octadecadienoate + NH4(+) => (9Z,12Z)-octadecadienamide + H2O


name: AMP(out) + CMP-N-acetyl-beta-neuraminate(in) <=> AMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Rattus norvegicus)


name: beta-nicotinamide D-riboside(in) => beta-nicotinamide D-riboside(out)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Drosophila melanogaster)


name: D-glutamine + H2O <=> D-glutamate + NH4(+)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Mus musculus)


name: hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 (Danio rerio)


name: Pol II elongation complex moves on the template as transcript elongates (Rattus norvegicus)


name: Caspase-mediated cleavage of plakophilin-1 (Canis familiaris)


name: 2-methylpropanoate + ATP => 2-methylpropanoyl phosphate + ADP


name: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose (Drosophila melanogaster)


name: Oligomerization of CARMA1 (Canis familiaris)


name: H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Dictyostelium discoideum)


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Caenorhabditis elegans)


name: ESR1 binds ESR1 agonists (Xenopus tropicalis)


name: 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP <=> AMP + diphosphate + H(+) + staphyloferrin B


name: 2-oxoglutarate + L-kynurenine => H2O + kynurenate + L-glutamate


name: A2E translocates to RPE cells (Homo sapiens)


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Sus scrofa)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Schizosaccharomyces pombe)


name: EML4 trimerizes (Caenorhabditis elegans)


name: FURIN translocates to the plasma membrane (Schizosaccharomyces pombe)


name: 5,6,7,8-tetrahydropteridine + NAD(+) <=> 6,7-dihydropteridine + H(+) + NADH


name: Phosphorylated KHDRBS1 translocates to the cytosol (Gallus gallus)


name: The phagophore extends from the PIP3-enriched structure (Sus scrofa)


name: L-aspartate + NH4(+) => H2O + L-asparagine


name: Interaction of MyoD:E protein with MEF2 (Danio rerio)


name: (9Z)-octadecenoate + AH2 + O2 = (12R)-hydroxy-(9Z)-octadecenoate + A + H2O


name: H(+) + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine => (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Danio rerio)


name: a sphingomyelin + H2O => a carboxylate + sphing-4-enine-phosphocholine


name: PC is hydrolyzed to 2-acyl LPC by PLA2G4C (Mus musculus)


name: Ubiquitination of NEMO by TRAF6 (Sus scrofa)


name: Polyubiquitinated NRIF migrates to the nucleus (Rattus norvegicus)


name: L1 and NCAM1 engaged in cis-interaction (Rattus norvegicus)


name: 3-oxopentanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxypentanoyl-[ACP] + NADP(+)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Danio rerio)


name: H2O + L-serine-phosphoethanolamine <=> H(+) + L-serine + phosphoethanolamine


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Sus scrofa)


name: 5-methyltetrahydropteroyltri-L-glutamate + L-selenohomocysteine <=> L-selenomethionine + tetrahydropteroyltri-L-glutamate


name: a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 2'-phosphate + H(+)


name: Co-precorrin-4 + S-adenosyl-L-methionine <=> Co-precorrin-5A + H(+) + S-adenosyl-L-homocysteine


name: G-protein beta/gamma-subunit complex binding


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Bos taurus)


name: a 5'-end phospho (purine-ribonucleoside) in mRNA + 2 H(+) + N(7)-methyl-GDP => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O


name: 11-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-[N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + H(+) + UDP


name: PTK6 phosphorylates STAT3 (Rattus norvegicus)


name: Formation of MCM2-7 complex (Plasmodium falciparum)


name: (9Z)-octadecenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphate = 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: Retromer recycles WLS to the Golgi (Bos taurus)


name: Cleavage of DNER:NOTCH1 complex releases NICD1 (Homo sapiens)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose <=> an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: Bile salts dissociate from FABP6 (Bos taurus)


name: ULK1 phosphorylates Beclin-1 (Caenorhabditis elegans)


name: N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Danio rerio)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Dictyostelium discoideum)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine <=> 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: glutarate(in) + xanthurenate(out) <=> glutarate(out) + xanthurenate(in)


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Bos taurus)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Caenorhabditis elegans)


name: BACE1(46-501) translocates from Golgi lumen to plasma membrane (Homo sapiens)


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Sus scrofa)


name: protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity


name: 4 (R)-methylmalonyl-CoA + 12 H(+) + long-chain fatty acyl-[mycocerosate synthase] + 8 NADPH <=> 4 CO2 + 4 CoA + 4 H2O + 8 NADP(+) + tetramethylated-mycocerosoyl-[mycocerosate synthase]


name: USP13 and OTUD3 deubiquitinate PTEN (Homo sapiens)


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Gallus gallus)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Schizosaccharomyces pombe)


name: SGT1:HSP90 binds inactive NLRP3 (Bos taurus)


name: Elastin degradation by elastin-degrading extracellular proteinases (Mus musculus)


name: 2-carboxy-D-arabinitol 1-phosphate + H2O = 2-carboxy-D-arabinitol + phosphate


name: 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine


name: a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-alpha-D-glucose => a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside + H(+) + UDP


name: Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Homo sapiens)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Schizosaccharomyces pombe)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Bos taurus)


name: MADCAM1-1 binds Integrin alpha4beta7 (Mus musculus)


name: 17beta-estradiol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 19-oxotestosterone + O2 + reduced [NADPH--hemoprotein reductase]


name: p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Sus scrofa)


name: GPRC6A can bind L-alpha amino acids and calcium (Homo sapiens)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Homo sapiens)


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Bos taurus)


name: (2S)-3-sulfopropanediol => H(+) + hydroxyacetone + sulfite


name: TLE tetramers bind TCF/LEF at WNT promoters (Danio rerio)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Rattus norvegicus)


name: Basigin homodimerises (Rattus norvegicus)


name: SLC36A4 transports extracellular L-Pro to the cytosol (Caenorhabditis elegans)


name: 2 cob(II)alamin-[cyanocobalamin reductase] + 2 hydrogen cyanide + NADP(+) => 2 apo-[cyanocobalamin reductase] + 2 cyanocob(III)alamin + H(+) + NADPH


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + H(+)(in) <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + H(+)(out)


name: Conjugation of SUMO1 to UBA2:SAE1 (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Canis familiaris)


name: FUOM isomerises alpha-Fuc to beta-Fuc (Canis familiaris)


name: NADP(+) + prostaglandin E2 <=> 15-oxoprostaglandin E2 + H(+) + NADPH


name: O2 + prostaglandin H2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxyprostaglandin H2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Plasmodium falciparum)


name: H(+) + hexan-3-one + NADPH + NH4(+) => 3-aminohexane + H2O + NADP(+)


name: 3'-phosphoadenylyl sulfate + glycodeoxycholate = 3alpha-sulfoglycodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: AMP + H(+) + riboflavin cyclic-4',5'-phosphate => FAD


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H2O <=> (9Z,12Z)-octadecadienoate + a 1-acyl-sn-glycero-3-phosphoethanolamine + H(+)


name: (2E)-geranyl phosphate + ADP + H(+) => (2E)-geraniol + ATP


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Sus scrofa)


name: 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + AH2 => (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + A


name: ERBB4 ubiquitination by WWP1/ITCH (Drosophila melanogaster)


name: SIRP alpha binds CD47 (Canis familiaris)


name: Maresin-like SPMs translocate from cytosol to extracellular region (Homo sapiens)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Mus musculus)


name: holo-[peptidyl-carrier protein] + L-arginyl-AMP <=> AMP + H(+) + L-arginyl-[peptidyl-carrier protein]


name: 2-oxoglutarate + O2 + thebaine <=> CO2 + formaldehyde + neopinone + succinate


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Homo sapiens)


name: Methylthio-ribose-P = Methylthio-ribulose-P (Xenopus tropicalis)


name: DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)


name: CDP-DAG is converted to PI by CDIPT (Schizosaccharomyces pombe)


name: (4R)-ipsdienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => beta-myrcene + O2 + reduced [NADPH--hemoprotein reductase]


name: Aquaporin-3 passively transports water out of cell (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA <=> 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: chloride(out) + glycine(out) + 2 Na(+)(out) => chloride(in) + glycine(in) + 2 Na(+)(in)


name: BAR domain proteins recruit dynamin (Caenorhabditis elegans)


name: SHP1 and SHP2 bind the common beta chain (Homo sapiens)


name: 2 H2O + NADP(+) + nigerone => 3 H(+) + NADPH + O2 + 2 rubrofusarin B


name: (E)-oct-2-en-1-ol + NADP(+) <=> (2E)-octenal + H(+) + NADPH


name: Dephosphorylation of Gab1 by SHP2 (Xenopus tropicalis)


name: phosphate + thiamine => H2O + thiamine phosphate


name: S1P binds S1PR3 in response to E2 stimulation (Mus musculus)


name: RNF152 polyubiquitinates RRAGA (Sus scrofa)


name: S-adenosyl-L-methionine + scutellarein 4'-methyl ether => ladanein + S-adenosyl-L-homocysteine


name: NCOA1 recruits EP300 to the ABCA1 promoter (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate = beta-acoradiene + diphosphate


name: an alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate <=> an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Caenorhabditis elegans)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate


name: CHSY1 transfers GlcA to chondroitin (Bos taurus)


name: 3-methylundecanoate + ATP + CoA <=> 3-methylundecanoyl-CoA + AMP + diphosphate


name: 3-chlorocatechol + H(+) + NADH => (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+)


name: RAC1 binds effectors at the ER membrane (Homo sapiens)


name: DUX4, TPRXL, TPRX1, and TPRX2 bind the DUXA gene (Homo sapiens)


name: GSTK1 dimer transfers GS from GSH to CDNB (Caenorhabditis elegans)


name: mTORC1 phosphorylates MAF1 (Drosophila melanogaster)


name: alcohol-forming long-chain fatty acyl-CoA reductase activity


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Sus scrofa)


name: Nuclear VBC complex ubiquitinylates HIF-alpha (Xenopus tropicalis)


name: KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine (Homo sapiens)


name: Bradykinin receptors B1 and B2 bind to bradykinin (Mus musculus)


name: 2 Fe(III)-[cytochrome c] + H2O + sulfite => 2 Fe(II)-[cytochrome c] + 2 H(+) + sulfate


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Homo sapiens)


name: NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Drosophila melanogaster)


name: OTULIN,USP5 cleaves UBB yielding ubiquitin (Dictyostelium discoideum)


name: pregnenolone sulfate(in) => pregnenolone sulfate(out)


name: Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Rattus norvegicus)


name: 4-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase] = 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: dTDP-3-dehydro-6-deoxy-alpha-D-galactose + L-glutamate => 2-oxoglutarate + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose


name: botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: 2,5-dihydroxybenzoate + H(+) => CO2 + hydroquinone


name: PIAS1,3 SUMOylates NR5A1 with SUMO2 (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(11Z,14Z,17Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = (11Z,14Z,17Z-eicosatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Homo sapiens)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Homo sapiens)


name: anthranilate + 2 ATP + L-tryptophan = (R)-benzodiazepinedione + 2 AMP + 2 diphosphate + H(+)


name: (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase] => 3beta-hydroxycostunolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: carnitine + H(+) => 2-methylcholine + CO2


name: SUMOylation of RARA with SUMO2 (Bos taurus)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Mus musculus)


name: DPP4(1-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Sus scrofa)


name: JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)