name: CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)


name: L-alanine + oxomalonate = aminomalonate + pyruvate


name: NTRK2-phosphorylated FRS2 binds GRB2 (Canis familiaris)


name: 5 CO2 + 6 CoA + dodecapentaneoyl-[polyketide synthase] + 5 H2O + 5 NADP(+) => acetyl-CoA + 10 H(+) + holo-[polyketide synthase] + 5 malonyl-CoA + 5 NADPH


name: ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Xenopus tropicalis)


name: 4-hydroxy-3-all-trans-nonaprenylbenzoate + diphosphate => 4-hydroxybenzoate + all-trans-nonaprenyl diphosphate


name: Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)


name: 3 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) => 3 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3)


name: AMP + an aromatic aldehyde + diphosphate + NADP(+) => an aromatic carboxylate + ATP + H(+) + NADPH


name: glyoxylate + L-serine <=> 3-hydroxypyruvate + glycine


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Bos taurus)


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Saccharomyces cerevisiae)


name: D-maltotetraose + H2O => alpha-D-glucose + D-maltotriose


name: ATP + H(+) + NADPH + octanoate => AMP + diphosphate + NADP(+) + octanal


name: demethyllactenocin + S-adenosyl-L-methionine <=> H(+) + lactenocin + S-adenosyl-L-homocysteine


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 = (8R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate


name: Formation of collagen fibrils (Drosophila melanogaster)


name: 2 formaldehyde + H2O => formate + H(+) + methanol


name: 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Xenopus tropicalis)


name: (9Z)-tetradecenoyl-CoA + H2O = adenosine 3',5'-bisphosphate + 2 H(+) + S-(9Z-tetradecenoyl)-4'-phosphopantetheine


name: NAD(+) + trans-4-hydroxycyclohexanecarboxylate <=> 4-oxocyclohexanecarboxylate + H(+) + NADH


name: 7,8-dihydroneopterin + O2 => 7,8-dihydroxanthopterin + formate + glycolaldehyde + H(+)


name: a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + H(+) + UDP => a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Homo sapiens)


name: CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Dictyostelium discoideum)


name: MEN1 binds SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA


name: CAD hexamer transforms CAP to N-carb-L-Asp (Dictyostelium discoideum)


name: BACH1 binds MAFK (Drosophila melanogaster)


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Xenopus tropicalis)


name: prostaglandin transmembrane transporter activity


name: JAK1 binds IL4R in IL4-bound IL4R1 (Rattus norvegicus)


name: NR1H2,3, NRIP1 bind the FASN gene (Homo sapiens)


name: ProGIP translocates from the ER Lumen to secretory granules (Sus scrofa)


name: 2 ATP + 2 cob(II)alamin + 2 H2O + reduced [electron-transfer flavoprotein] => 2 adenosylcob(III)alamin + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Bos taurus)


name: PECAM1 is phosphorylated (Gallus gallus)


name: UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG (Homo sapiens)


name: (15S)-hydroperoxy-(11Z,13E)-eicosadienoate => (11Z,14Z)-eicosadienoate + O2


name: ABC-type teichoic acid transporter activity


name: ALDH3B1 oxidises HXAL to PALM (Bos taurus)


name: 4alpha-methylzymosterol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 <=> 4alpha-carboxyzymosterol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: ATG12 binds ATG7 dimer (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + CoA


name: 2 H(+) + L-histidine + NADH => H2O + L-histidinal + NAD(+)


name: ATP + H2O + L-alanyl-L-glutamine(out) <=> ADP + H(+) + L-alanyl-L-glutamine(in) + phosphate


name: CO2 + 3 H(+) + precorrin-8X + 2 S-adenosyl-L-homocysteine => precorrin-6B + 2 S-adenosyl-L-methionine


name: Dissociation of the P2Y purinoceptor 1:Gq complex (Gallus gallus)


name: H(+) + L-xylulose + NADH => NAD(+) + xylitol


name: (9Z)-octadecenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol <=> 1,2-di-(9Z-octadecenoyl)-glycerol + CoA


name: Dynamin is recruited to the gap junction plaque (Drosophila melanogaster)


name: a 7(1)-hydroxybacteriochlorophyllide c + H2O + S-adenosyl-L-methionine => 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide c + H(+) + L-methionine


name: Activated FGFR3 phosphorylates FRS3 (Danio rerio)


name: 9-cis-retinol + hexadecanoyl-CoA = 9-cis-retinyl hexadecanoate + CoA


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Rattus norvegicus)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O => [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: (R)-2-hydroxy-4-methylpentanoate + NAD(+) = 4-methyl-2-oxopentanoate + H(+) + NADH


name: Rap1 signal termination by Rap1GAPs (Canis familiaris)


name: SDK1 homophillic interaction (Gallus gallus)


name: ABCC3 transports bile salts from cytosol to extracellular region (Bos taurus)


name: AH2 + demethylspheroidene => 1-hydroxy-all-trans-1,2-dihydro-neurosporene + A


name: GSTZ1 dimer dehalogenates DCA to glyoxylate (Caenorhabditis elegans)


name: VAV2 is a GEF for Rho/Rac family kinases (Mus musculus)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Mus musculus)


name: (2S)-2-amino-2'-deoxyadenylo-succinate + ADP + 2 H(+) + phosphate => ATP + dGMP + L-aspartate


name: FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS (Homo sapiens)


name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA (Homo sapiens)


name: dIMP + H2O <=> 2'-deoxyinosine + phosphate


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Rattus norvegicus)


name: D-alanine(in) + H(+)(in) <=> D-alanine(out) + H(+)(out)


name: LONP1 binds mitochondrial inner membrane proteins (Dictyostelium discoideum)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Canis familiaris)


name: Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 (Drosophila melanogaster)


name: LGI3 binds ADAM22,23,synatxin1 (Gallus gallus)


name: 3 H(+) + 3 NADPH + 3 O2 + probetaenone I => betaenone B + 3 H2O + 3 NADP(+)


name: Arachidonate diffuses across the ER membrane (Homo sapiens)


name: myo-inositol + phosphate => 1D-myo-inositol 1-phosphate + H2O


name: acetoacetyl-CoA + H(+) + NADPH => (3R)-3-hydroxybutanoyl-CoA + NADP(+)


name: RHOD:GTP translocates to the endosome membrane (Bos taurus)


name: MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) (Homo sapiens)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O => an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + N-acetyl-D-galactosamine


name: CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine (Homo sapiens)


name: Association of DFF40 with DFF45 (Homo sapiens)


name: misfolded CFTR is degraded by the 26S proteasome (Dictyostelium discoideum)


name: PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ADP + H(+) + phosphate => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ATP + H2O


name: SPHK2 binds SPHK2 inhibitors (Bos taurus)


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Bos taurus)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Gallus gallus)


name: H(+)(out) + L-alanyl-L-valine(out) = H(+)(in) + L-alanyl-L-valine(in)


name: Ubiquitinated Orc1 is degraded by the proteasome (Dictyostelium discoideum)


name: BRAP autoubiquitinates (Xenopus tropicalis)


name: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: (E)-4-hydroxynon-2-enoate + 2 H(+) + NADPH => (E)-4-hydroxynon-2-enal + H2O + NADP(+)


name: diphosphate + IC-asc-C7-AMP => ATP + H(+) + IC-asc-C7


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Drosophila melanogaster)


name: SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Sus scrofa)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Homo sapiens)


name: SFKs phosphorylate VAV2,3 (Canis familiaris)


name: a 21-hydroxy-C21-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase]


name: 13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+) <=> 15-oxoprostaglandin F1alpha + H(+) + NADPH


name: ATP + CoA + pentadecanoate = AMP + diphosphate + pentadecanoyl-CoA


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Canis familiaris)


name: 7(1)-hydroxychlorophyll a + NADP(+) = chlorophyll b + H(+) + NADPH


name: 5,6,7,8-tetrahydromethanopterin + formaldehyde <=> 5,10-methylenetetrahydromethanopterin + H2O


name: Ghrelin O-acyltransferase octanoylates Proghrelin (Canis familiaris)


name: BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Mus musculus)


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Rattus norvegicus)


name: Interaction of PECAM-1 and PLC gamma1 (Homo sapiens)


name: PP6-PPP6R3 dephosphorylates TERF2 (Sus scrofa)


name: GLUT7 and GLUT11 transport glucose and fructose (Plasmodium falciparum)


name: 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H(+) + H2O = NH4(+) + pre-mycofactocin


name: DIT and MIT combine to form triiodothyronine (Dictyostelium discoideum)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + phomopsene


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Danio rerio)


name: 4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+) => dihydrocarvone + H(+) + NADPH + O2


name: 3-(4-hydroxyphenyl)pyruvate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + L-tyrosine


name: 2,6-dinitrotoluene + NADH + O2 = 3-methyl-4-nitrocatechol + NAD(+) + nitrite


name: AGK:Mg2+ phosphorylates MAG, DAG (Danio rerio)


name: dihydroprecondylocarpine acetate = acetate + catharanthine + H(+)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Rattus norvegicus)


name: ATP + H2O + L-alanyl-L-histidine(out) => ADP + H(+) + L-alanyl-L-histidine(in) + phosphate


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Homo sapiens)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Mus musculus)


name: H(+) + N(1)-methylguanosine(748) in 23S rRNA + S-adenosyl-L-homocysteine => guanosine(748) in 23S rRNA + S-adenosyl-L-methionine


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol = all-trans-retinyl hexadecanoate + hexadecanoyl-sn-glycero-3-phosphocholine


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H(+) + NADPH => CDP-alpha-D-paratose + NADP(+)


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Xenopus tropicalis)


name: O2 + octanedioyl-CoA => (2E)-octenedioyl-CoA + H2O2


name: 2-oxobutanoate + L-alanine <=> (2S)-2-aminobutanoate + pyruvate


name: ATP + beta-alanine + H(+) <=> beta-alanyl-5'-AMP + diphosphate


name: phosphatidylinositol phospholipase C activity


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Sus scrofa)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 => (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O


name: NADP(+) + octacosanoyl-CoA => (2E)-octacosenoyl-CoA + H(+) + NADPH


name: CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D (Homo sapiens)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Danio rerio)


name: cyclic ADP-beta-D-ribose + H(+) + nicotinamide => NAD(+)


name: (2E,4E)-tetradecadienoyl-CoA + H(+) + NADPH <=> (3E)-tetradecenoyl-CoA + NADP(+)


name: Formation of fatty acid synthase (FAS) dimer (Dictyostelium discoideum)


name: (R)-carnitine + hexadecanoyl-CoA <=> CoA + O-hexadecanoyl-(R)-carnitine


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Dictyostelium discoideum)


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Xenopus tropicalis)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Sus scrofa)


name: H2O + NAD(+) + vanillin <=> 2 H(+) + NADH + vanillate


name: lathosterol + NAD(+) = 5alpha-cholest-7-en-3-one + H(+) + NADH


name: ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Canis familiaris)


name: MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine (Homo sapiens)


name: SMAD7 binds to SMURF2 (Drosophila melanogaster)


name: STAB1 (FEEL-1) binds ligands (Bos taurus)


name: Activated FGFR4 phosphorylates SHC1 (Gallus gallus)


name: CYP4F2, 4F3 20-hydroxylate LTB4 (Homo sapiens)


name: FMNL2 binds CDC42:GTP (Canis familiaris)


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Saccharomyces cerevisiae)


name: NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione


name: PDCL promotes G-protein beta 5 folding (Caenorhabditis elegans)


name: HCMV C Nucleocapsid Translocation (Homo sapiens)


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + NADP(+) => 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + H(+) + NADPH


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Canis familiaris)


name: NaS1 co-transports sulphate and a sodium ion (Xenopus tropicalis)


name: L-xylose + NADP(+) <=> H(+) + L-xylono-1,4-lactone + NADPH


name: H(+) + NADPH + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose <=> NADP(+) + UDP-2-acetamido-2,6-dideoxy-beta-L-talose


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Dictyostelium discoideum)


name: Phosphorylation of SHC1 by ERBB4 homodimers (Homo sapiens)


name: L-tyrosine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)


name: GDP-alpha-D-mannose + H2O <=> alpha-D-mannose 1-phosphate + GMP + 2 H(+)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Homo sapiens)


name: AH2 + protoaustinoid B => A + protoaustinoid A


name: EEF1A1 dissociates from p-GFAP (Homo sapiens)


name: 15,17(3)-seco-F430-17(3)-acid + ATP = ADP + coenzyme F430 + phosphate


name: TXLNA (IL14) binds syntaxin4 (Dictyostelium discoideum)


name: AKT1 phosphorylates NOTCH4 (Drosophila melanogaster)


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Gallus gallus)


name: "mannan-binding lectin-associated serine protease-2"


name: Ubiquitinated Orc1 enters the cytosol (Saccharomyces cerevisiae)


name: Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) (Homo sapiens)


name: benzoyl-CoA + hexan-2-ol <=> CoA + hexan-2-yl benzoate


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+) => a 1,2-diacyl-sn-glycerol + ATP


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) + N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein] <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-histidyl-[protein]


name: SEMA4D interacts with Plexin-B1:ErbB2 (Caenorhabditis elegans)


name: Translocation of Cdc25B to the cytoplasm (Mus musculus)


name: ATP + taurocyamine => ADP + H(+) + N-phosphotaurocyamine


name: p-VAV family:PIP3 binds RAC1:GDP (Caenorhabditis elegans)


name: SREBP1A,1C,2 translocates to the nucleus (Mus musculus)


name: (9Z)-octadecenoate + 1,2-di-(9Z-octadecenoyl)-glycerol + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O


name: Internalization of ubiquitinated FLT3 (Canis familiaris)


name: H2O + O2 + spermidine => 3-aminopropanal + H2O2 + putrescine


name: 2 ATP + 2 H2O + 2 L-glutamine + Ni-sirohydrochlorin => 2 ADP + 2 H(+) + 2 L-glutamate + Ni-sirohydrochlorin a,c-diamide + 2 phosphate


name: PCK1 phosphorylates OA to yield PEP (Xenopus tropicalis)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Rattus norvegicus)


name: 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA + S-adenosyl-L-methionine => 5'-deoxyadenosine + archaeosine(15) in tRNA + 2 H(+) + L-1-piperideine-6-carboxylate + L-methionine


name: CTP(out) + dUMP(in) => CTP(in) + dUMP(out)


name: COP9 and TOR1 deneddylate STON2 (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: H2O + presqualene monophosphate = phosphate + presqualene alcohol


name: O2 + pregnenolone + reduced [NADPH--hemoprotein reductase] => 7alpha-hydroxypregnenolone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 3'-end 2'-deoxyribonucleotide-3'-(L-tyrosyl phosphate)-DNA + H2O = a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H(+) + L-tyrosine


name: 15-methylhexadecanoate + H(+) + NADPH + O2 => H2O + NADP(+) + omega-hydroxy-15-methyl-hexadecanoate


name: adenine + H(+) + H2O = hypoxanthine + NH4(+)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Homo sapiens)


name: a 4,5-saturated-(3E)-enoyl-CoA + NADP(+) => a (2E,4E)-dienoyl-CoA + H(+) + NADPH


name: PTPN1 and PTPN2 dephosphorylate MET (Canis familiaris)


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Sus scrofa)


name: a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]


name: 3-oxodecanoyl-[ACP] + CO2 + holo-[ACP] => H(+) + malonyl-[ACP] + octanoyl-[ACP]


name: 12-methyloctadecanoate + ATP + CoA <=> 12-methyloctadecanoyl-CoA + AMP + diphosphate


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Canis familiaris)


name: 15-cis-phytoene + diphosphate => (1R,2R,3R)-prephytoene diphosphate


name: SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol (Rattus norvegicus)


name: a 4-hydroxynonenal + H(+) + NADPH => a 4-hydroxynonen-1-ol + NADP(+)


name: H2O + N-eicosanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => (9Z)-octadecenoate + H(+) + N-eicosanoyl-sn-glycero-3-phosphoethanolamine


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]


name: CYTH proteins stimulate ARF1 GTPase activity (Gallus gallus)


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Xenopus tropicalis)


name: AMP + diphosphate + H(+) + NAD(+) => ATP + deamido-NAD(+) + NH4(+)


name: H2O + pyridine N-oxide => H2O2 + pyridine


name: JMJD1C demethylates H3K9 mono- and di-methylation (Drosophila melanogaster)


name: Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Canis familiaris)


name: D-alanyl-D-alanine + H2O <=> 2 D-alanine


name: C5b:C6:C7 translocates to the plasma membrane (Homo sapiens)


name: 5-methyluridine(54) in tRNA + [TtuB sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + ATP + H2O <=> 5-methyl-2-thiouridine(54) in tRNA + [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + AMP + diphosphate + 2 H(+)


name: Dimerization of FGFR2 point mutants with enhanced kinase activity (Homo sapiens)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Saccharomyces cerevisiae)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Xenopus tropicalis)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Homo sapiens)


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Danio rerio)


name: 2 cob(II)yrinate a,c diamide + FMNH2 => 2 cob(I)yrinate a,c diamide + FMN + 3 H(+)


name: Oxytocin receptor bind oxytocin (Danio rerio)


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Canis familiaris)


name: ADP + D-galactose(in) + H(+) + phosphate => ATP + D-galactose(out) + H2O


name: histone H3K23 acetyltransferase activity


name: JAK2-activated MAPKs phosphorylate YBX1 (Gallus gallus)


name: Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Mus musculus)


name: adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate => phosphate + S-methyl-5'-thioadenosine


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Homo sapiens)


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: ATP + H2O + tungstate(in) = ADP + H(+) + phosphate + tungstate(out)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Mus musculus)


name: campesterol + O2 + reduced [NADPH--hemoprotein reductase] = (22S)-22-hydroxycampesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Dictyostelium discoideum)


name: UDP-glucose is oxidised to UDP-glucuronate (Caenorhabditis elegans)


name: 2 H(+) + NADH + 2 O2 + protoviolaceinate => CO2 + 2 H2O + NAD(+) + violacein


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Caenorhabditis elegans)


name: H(+) + trans-aconitate => CO2 + itaconate


name: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity


name: Gap-filling DNA synthesis in SDSA (Homo sapiens)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Rattus norvegicus)


name: (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 => (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2


name: 2 glutathione + H(+) + methylarsonate <=> glutathione disulfide + H2O + methylarsonous acid


name: GPX5,6 reduce H2O2 to H2O (Mus musculus)


name: L-threonine + phosphate => H2O + O-phospho-L-threonine


name: Growth hormone forms dimers and oligomers (Bos taurus)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Sus scrofa)


name: 2-hydroxyethylphosphonate + NAD(+) <=> H(+) + NADH + phosphonoacetaldehyde


name: G protein-coupled serotonin receptor activity


name: Transport of MCP:pPR-AP:pAP Complex into the Nucleous (Homo sapiens)


name: GGCT transforms gGluCys to OPRO (Xenopus tropicalis)


name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density (Homo sapiens)


name: an oxoeicosatetraenoate + H2O => a hydroperoxyeicosatetraenoate


name: L-asparaginyl-[protein] + UDP-alpha-D-glucose <=> H(+) + N(4)-(beta-D-glucosyl)-L-asparaginyl-[protein] + UDP


name: beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose = beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP + H(+)


name: DHF is reduced to tetrahydrofolate (THF) (Homo sapiens)


name: MTMR4 dephosphorylates SMAD2/3 (Canis familiaris)


name: 3-dehydro-6-deoxoteasterone + NADP(+) <=> (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + NADPH


name: LDH tetramer oxidises LACT to PYR (Bos taurus)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Homo sapiens)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Drosophila melanogaster)


name: P2Y14 receptor can bind to UDP-glucose (Sus scrofa)


name: 14-3-3epsilon attentuates NADE-related apoptosis (Homo sapiens)


name: 2-methyloctadecanoyl-CoA + H2O <=> 2-methyloctadecanoate + CoA + H(+)


name: TNFSF18 binds TNFRSF18 (Canis familiaris)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Gallus gallus)


name: ALDH3A2-2 oxidizes pristanal to pristanate (Caenorhabditis elegans)


name: NAD(+) + taurocholate <=> 7-oxo-taurodeoxycholate + H(+) + NADH


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+) => 1D-myo-inositol 3-phosphate + a CDP-1,2-diacyl-sn-glycerol


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Drosophila melanogaster)


name: (6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate


name: MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Homo sapiens)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Bos taurus)


name: 16-epivellosimine + acetyl-CoA <=> CoA + vinorine


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Mus musculus)


name: H2O + N-acetylputrescine = acetate + putrescine


name: ASPG hydrolyses L-Asn to L-Asp (Sus scrofa)


name: (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+) => 3-methylcatechol + H(+) + NADH


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Bos taurus)


name: H(+) + H2O + N-isopropylammelide = cyanurate + isopropylamine


name: p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)


name: (2Z,6E)-farnesyl diphosphate => (6R,7S)-2,2,6-trimethyl-10-methylenebicyclo[5.4.0]undec-1(11)-ene + diphosphate


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Sus scrofa)


name: Docking of the TAP:EJC Complex with the NPC (Homo sapiens)


name: 7-oxocholesterol + H(+) + NADPH <=> 7beta-hydroxycholesterol + NADP(+)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Danio rerio)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Bos taurus)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Canis familiaris)


name: A + H2O + quinolin-8-ol = 8-hydroxyquinolin-2(1H)-one + AH2


name: SUMOylation of HDAC1 with SUMO1 (Gallus gallus)


name: ABCAs mediate lipid efflux (Gallus gallus)


name: Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Gallus gallus)


name: ADK phosphorylates RBV (Rattus norvegicus)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Caenorhabditis elegans)


name: 2 Na(+)(out) + tauro-beta-muricholate(out) <=> 2 Na(+)(in) + tauro-beta-muricholate(in)


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O => 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: Phosphorylation and activation of VAV2/VAV3 by SYK (Mus musculus)


name: HMIT co-transports myo-inositol with a proton (Mus musculus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + octanoyl-CoA <=> 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA


name: Phosphorylation of PIP2 to PIP3 by PI3K (Drosophila melanogaster)


name: Collagen type I degradation by MMP15 (Sus scrofa)


name: 3 O2 + quiannulatene + 3 reduced [NADPH--hemoprotein reductase] = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + quiannulatate


name: TIRAP binds PIP2-rich regions in the plasma membrane (Canis familiaris)


name: TP53 binds the complex of JMY, EP300 and TTC5 (Homo sapiens)


name: GDP-beta-L-colitose + NADP(+) = GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + H(+) + NADPH


name: (4S)-4-hydroxy-L-glutamate + H(+) + NADH => (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + 2 H2O + NAD(+)


name: demethyllactenocin + S-adenosyl-L-methionine = H(+) + lactenocin + S-adenosyl-L-homocysteine


name: GAB1 recruits CRK,CRKL to MET (Rattus norvegicus)


name: p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Sus scrofa)


name: 3-(4-hydroxyphenyl)pyruvate + O2 => CO2 + homogentisate


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Saccharomyces cerevisiae)


name: a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol <=> a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+)


name: p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Homo sapiens)


name: DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)


name: Activated MAPKs phosphorylate MAP2K1 (Saccharomyces cerevisiae)


name: MTTP lipidates APOB-100, forming a pre-VLDL (Homo sapiens)


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Rattus norvegicus)


name: cyclic tetraadenylate = 2 5'-hydroxy-diadenylate 2',3'-cylic phosphate


name: HCO3- transport through ion channel (Drosophila melanogaster)


name: Activation of RAC1 by the PXN:CRK complex (Bos taurus)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Sus scrofa)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Mus musculus)


name: CoA + H(+) + octanedioate => H2O + octanedioyl-CoA


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose <=> an alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: H(+) + hexadecanoyl-CoA + L-alanine => 1-deoxy-3-dehydrosphinganine + CO2 + CoA


name: L-tyrosine(in) + Na(+)(in) = L-tyrosine(out) + Na(+)(out)


name: "infectious pancreatic necrosis birnavirus Vp4 peptidase"


name: all-trans-retinol + NADP(+) = all-trans-retinal + H(+) + NADPH


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Canis familiaris)


name: 3 Fe(III)-[cytochrome c] + H2O + hydrazine = 3 Fe(II)-[cytochrome c] + 2 H(+) + NH4(+) + nitric oxide


name: HGSNAT oligomer acetylates Heparan chain(1) (Dictyostelium discoideum)


name: NADPH + 2 oxidized [4Fe-4S]-[ferredoxin] => H(+) + NADP(+) + 2 reduced [4Fe-4S]-[ferredoxin]


name: USP17 deubiquitinates SUDS3 (Danio rerio)


name: NOX4, NOX5 reduce O2 to O2.- (Dictyostelium discoideum)


name: 2 H(+) + H2O + N-hydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase] => L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase]


name: Activation of Edited Kainate receptors (Rattus norvegicus)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Mus musculus)


name: EP400 binds CDKN1A promoter (Sus scrofa)


name: MSL acetylates histone H4 (Mus musculus)


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Mus musculus)


name: Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)


name: 3,3',5'-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) => 3,3',5'-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: OPLAH hydrolyses OPRO to L-Glu (Drosophila melanogaster)


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Rattus norvegicus)


name: 3-chloro-4-methylcatechol + NAD(+) + nitrite => 2-chloro-4-nitrotoluene + NADH + O2


name: 2-oxoglutarate + O2 + octyl sulfate <=> CO2 + H(+) + octanal + succinate + sulfate


name: (R)-malate + NAD(+) <=> CO2 + NADH + pyruvate


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Canis familiaris)


name: Formation of the MLL3 complex (Drosophila melanogaster)


name: 2-oxoglutarate + N(6)-methyladenosine in U6 snRNA + O2 => adenosine in U6 snRNA + CO2 + formaldehyde + succinate


name: Interleukin-5 is a homodimer (Mus musculus)


name: N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-asparaginyl-[protein] + UDP


name: oxaloacetate secondary active transmembrane transporter activity


name: RIPK1 is cleaved by CASP8:FLIP(L) (Canis familiaris)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Xenopus tropicalis)


name: 17beta-hydroxy-5alpha-androstan-3-one + NAD(+) = 5alpha-androstan-3,17-dione + H(+) + NADH


name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine (Xenopus tropicalis)


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Danio rerio)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Bos taurus)


name: DPH6 ligates ammonium to diphthine-EEF2 (Bos taurus)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Xenopus tropicalis)


name: DAAM1 recruits GTP-bound RHOA (Homo sapiens)


name: glyoxylate + NH4(+) => 2-iminoacetate + H2O


name: Formation of ORC(2-5) complex (Mus musculus)


name: Protein M2-1 tetramers bind protein P tetramer (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1,2-dihexanoylglycerol = 1,2-dihexanoyl-3-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + CoA


name: linear malto-oligosaccharide phosphorylase activity


name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Bos taurus)


name: Activated PTK6 binds CDKN1B (Homo sapiens)


name: 3,4,5-trihydroxybenzoate + H(+) => 1,2,3-trihydroxybenzene + CO2


name: Phosphorylation of USP8 by P-AKT (Dictyostelium discoideum)


name: 5-methylorsellinate + 3 CO2 + 4 CoA + S-adenosyl-L-homocysteine => acetyl-CoA + H(+) + 3 malonyl-CoA + S-adenosyl-L-methionine


name: Phosphorylation of IKKs complex mediated by MEKK1 (Gallus gallus)


name: EGR1 binds the TPH1 promoter (Homo sapiens)


name: 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate = H2O + ML-236C carboxylate


name: p190RhoGAP binds Plexin-B1 (Xenopus tropicalis)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Gallus gallus)


name: 3-methyl-2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 2-methylpropanoyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: (4R)-4-hydroxy-2-oxoglutarate => glyoxylate + pyruvate


name: Activation of RAC1 by VAV2/3 (Drosophila melanogaster)


name: a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Bos taurus)


name: Transport of the export-competent mRNP complex through the NPC (Gallus gallus)


name: guanidinoacetate + S-adenosyl-L-methionine => creatine + H(+) + S-adenosyl-L-homocysteine


name: Dopa is oxidized to dopaquinone by TYR (Homo sapiens)


name: carbamoyl phosphate + ornithine => citrulline + orthophosphate (Rattus norvegicus)


name: SLC22A1 transports Cipro into renal cell (Bos taurus)


name: (S)-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] <=> (13S,14R)-1,13-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: COMT transfers Met to DOPAC to form HVA (Homo sapiens)


name: CoA + H(+) + N-acyl-3-oxosphinganine => 3-oxosphinganine + a fatty acyl-CoA


name: Trimerization of the FASL:FAS receptor complex (Bos taurus)


name: GAR + 10-Formyl-THF => FGAR + THF (Xenopus tropicalis)


name: all-trans-decaprenyl diphosphate + 7 diphosphate => (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate


name: H(+) + orotidine 5'-phosphate => CO2 + UMP


name: SUMOylation of NFKBIA with SUMO1 (Mus musculus)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Bos taurus)


name: Autophosphorylation and activation of CAMK2 (Plasmodium falciparum)


name: (3R)-hydroxyhexanoyl-[ACP] <=> (2E)-hexenoyl-[ACP] + H2O


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate = 2-oxoglutarate + GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: H2O2 + NH4(+) + pre-mycofactocin => 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + H2O + O2


name: Vanin hydrolyses pantetheine to PanK, 2AET (Rattus norvegicus)


name: (S)-malate + UDP-N-acetyl-alpha-D-glucosamine = (S)-malyl N-acetyl-alpha-D-glucosaminide + H(+) + UDP


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Drosophila melanogaster)


name: Branching and elongation of mother and daughter filaments (Sus scrofa)


name: GDP + methylglyoxal => N(2)-(1-hydroxy-2-oxopropyl)-GDP


name: 2-oxoglutarate + N(2)-acetyl-L-ornithine <=> L-glutamate + N-acetyl-L-glutamate 5-semialdehyde


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] => 17-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADAMTS13 cleaves VWF variant multimer (Homo sapiens)


name: LRP2 binds extracellular TCN2:RCbl (Rattus norvegicus)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Bos taurus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Homo sapiens)


name: 5-methylsulfanyl-2,3-dioxopentyl phosphate => 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate


name: SUMOylation of PIAS4 with SUMO1 (Gallus gallus)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Dictyostelium discoideum)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Canis familiaris)


name: TGN-lysosomal vesicle coat assembly (Homo sapiens)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Bos taurus)


name: 3-dehydro-4-O-phospho-D-erythronate + H(+) => CO2 + dihydroxyacetone phosphate


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Homo sapiens)


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Danio rerio)


name: (R)-miconazole(in) + ATP + H2O => (R)-miconazole(out) + ADP + H(+) + phosphate


name: ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)


name: JMJD6 demethylates MeR3-histone H3 (Sus scrofa)


name: BCDX2 complex formation (Canis familiaris)


name: B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Bos taurus)


name: DNA polymerase:primase binds G-strand of the telomere (Canis familiaris)


name: ATM binds PEX5 (Schizosaccharomyces pombe)


name: hexadecanoyl-CoA + sn-glycerol 3-phosphate <=> 1-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: a plastoquinone + (n+1) H(+)(in) + NADH => a plastoquinol + n H(+)(out) + NAD(+)


name: HILPDA binds lipid droplets (Homo sapiens)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Dictyostelium discoideum)


name: Association of procollagen type IX (Xenopus tropicalis)


name: ING2-bound EP300 acetylates TP53 (Canis familiaris)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Drosophila melanogaster)


name: a 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA => a 1-acyl-sn-glycero-3-phosphate + octadecanoyl-CoA


name: (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+) = 3-chlorocatechol + H(+) + NADH


name: Thr-180 of ULK1 is phosphorylated (Dictyostelium discoideum)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => diphosphate + fusoxypene C


name: RPE65 isomero-hydrolyses atREs to 11cROL (Drosophila melanogaster)


name: L-histidine + 3 S-adenosyl-L-methionine = 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Drosophila melanogaster)


name: PSPN binds RET:GFRA4 (Rattus norvegicus)


name: 2 2-oxoglutarate + gibberellin A53 + H(+) + 3 O2 <=> 3 CO2 + gibberellin A20 + 2 H2O + 2 succinate


name: Translocation of STAT1 dimer to nucleus (Drosophila melanogaster)


name: H(+) + L-serine + tetradecanoyl-CoA => 3-oxohexadecasphinganine + CO2 + CoA


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-alpha-D-galactose <=> H(+) + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP


name: Association of MRE11 with RAD50 (Gallus gallus)


name: long-chain fatty acyl-CoA hydrolase activity


name: a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)


name: pelargonidin 3-O-beta-D-galactoside betaine + UDP => pelargonidin + UDP-alpha-D-galactose


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Caenorhabditis elegans)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)


name: GBF1 recruits ARF:GDP to the Golgi (Mus musculus)


name: a menaquinone + H(+) + NADH => a menaquinol + NAD(+)


name: NAMPT transfers PRIB to NAM to form NAMN (Xenopus tropicalis)


name: Photons induce isomerization of 11c-retinyl to at-retinyl (Caenorhabditis elegans)


name: H(+) + oxidized [electron-transfer flavoprotein] + undecanoyl-CoA = reduced [electron-transfer flavoprotein] + trans-2-undecenoyl-CoA


name: 3-methylundecanoate + ATP + CoA => 3-methylundecanoyl-CoA + AMP + diphosphate


name: H2O + IMP <=> 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide


name: CGRP receptor can bind calcitonin gene-related peptides (Canis familiaris)


name: KMT2A trimethylates nucleosomes at the SPI1 gene locus producing H3K4Me3 mark (Homo sapiens)


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Rattus norvegicus)


name: H2O + N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine = D-glucose + N-acyl-15-methylhexadecasphing-4-enine


name: an alcohol + D-glucuronate => a beta-D-glucuronoside + H2O


name: NCEH1 hydrolyzes cholesterol esters (Sus scrofa)


name: H(+) + N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine => cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine


name: D-5-[2-(methylsulfanyl)ethyl]hydantoin + H2O => H(+) + N-carbamoyl-D-methionine


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-corvol ether A + diphosphate


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Mus musculus)


name: 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H(+) + H2O


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Gallus gallus)


name: 2-oxoglutaramate + H2O <=> 2-oxoglutarate + NH4(+)


name: (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Sus scrofa)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers (Homo sapiens)


name: (3S)-hydroxyhexadecanedioyl-CoA + NAD(+) <=> 3-oxohexadecanedioyl-CoA + H(+) + NADH


name: (E)-caffeoyl-CoA + putrescine = CoA + H(+) + N-caffeoylputrescine


name: N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: Phosphorylation and release of IRF3  (Homo sapiens)


name: 2-oxoglutarate + 3-methyldodecanoyl-CoA + O2 => 2-hydroxy-3-methyldodecanoyl-CoA + CO2 + succinate


name: BTN3A1 and BTN1A1 binds periplakin (PPL) (Xenopus tropicalis)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Danio rerio)


name: Hyperphosphorylated IRAK1 associates with TRAF6 (Canis familiaris)


name: [trehalose-6-phosphate synthase]-L-cysteine + S-adenosyl-L-methionine <=> [trehalose-6-phosphate synthase]-S-methyl-L-cysteine + H(+) + S-adenosyl-L-homocysteine


name: CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Homo sapiens)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Rattus norvegicus)


name: beta-D-glucose + phloretin => H2O + phlorizin


name: [(2->1)-beta-D-fructosyl](n) + sucrose <=> [(2->1)-beta-D-fructosyl](n+1) + D-glucose


name: (S)-cheilanthifoline + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-stylopine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: TRIAP1 binds PRELID1, PRELID3A (Schizosaccharomyces pombe)


name: a ganglioside GP1c (d18:1(4E)) + H2O => a ganglioside GQ1c (d18:1(4E)) + N-acetylneuraminate


name: HP1 alpha binds Histone H3K9(me)3 (Plasmodium falciparum)


name: NPC2 transfers CHOL to NPC1 (Rattus norvegicus)


name: PDGF dimer binds two receptors simultaneously (Danio rerio)


name: 11-hydroxyferruginol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => carnosate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 11-oxo-beta-amyrin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 11alpha-hydroxy-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphocholine = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Caenorhabditis elegans)


name: D-sorbitol + NADP(+) = H(+) + L-xylo-3-hexulose + NADPH


name: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 <=> CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit]


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine <=> diphthine-[translation elongation factor 2] + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: (12Z)-10-hydroxyoctadecenoate + H2O => 10,13-dihydroxyoctadecanoate


name: 2'-deoxyadenosine + phosphate <=> 2-deoxy-alpha-D-ribose 1-phosphate + adenine


name: D-cellohexaono-1,5-lactone + H2O => D-cellohexaonate + H(+)


name: (R)-carnitine(out) + Na(+)(out) = (R)-carnitine(in) + Na(+)(in)


name: a quinone + succinate <=> a quinol + fumarate


name: FadD26, FadD28 transfer adenylyl group to a LCFA (Mycobacterium tuberculosis)


name: H2O + leukotriene C4 = L-glutamate + leukotriene D4


name: (8S)-annullatin E + dimethylallyl diphosphate => (8S)-annullatin J + diphosphate


name: a 1-acyl-sn-glycero-3-phosphate + H2O <=> a 1-acyl-sn-glycerol + phosphate


name: Interaction of Tie2 with Ang1 (Bos taurus)


name: an omega-hydroxy fatty acid + NAD(+) => an omega-oxo fatty acid + H(+) + NADH


name: Crk's SH3 domain engages C3G (Bos taurus)


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Sus scrofa)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Canis familiaris)


name: 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-octadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine


name: a 1,2-diacyl-sn-glycerol + CDP-ethanolamine <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] => erythrodiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine => 3-amino-2,3-dideoxy-scyllo-inosose + 5'-deoxyadenosine + H(+) + L-methionine


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Drosophila melanogaster)


name: misspliced mutants of LRP5 support enhanced beta-catenin-dependent signaling (Homo sapiens)


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Canis familiaris)


name: (S)-3-methyl-2-oxopentanoate + H(+) <=> 2-methylbutanal + CO2


name: KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Mus musculus)


name: NFE2L2 translocates from cytosol to nucleoplasm (Canis familiaris)


name: PP2A demethylation by PPME1 (Xenopus tropicalis)


name: 5,6-dihydrouridine(20a) in tRNA + NAD(+) <=> H(+) + NADH + uridine(20a) in tRNA


name: a 1,2-diacyl-sn-glycerol + a sterol <=> a 1-acyl-sn-glycerol + a sterol ester


name: Translocation of PLC-gamma1 to PIP2 (Rattus norvegicus)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Canis familiaris)


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Bos taurus)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Rattus norvegicus)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Sus scrofa)


name: nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) (Homo sapiens)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Caenorhabditis elegans)


name: CDC42:GTP binds PAK2 (Caenorhabditis elegans)


name: (4R)-hydroxysphinganine + ATP = (4R)-hydroxysphinganine 1-phosphate + ADP + H(+)


name: T2Rs bind bitter-tasting compounds (Xenopus tropicalis)


name: TRIF:activated TLR3/TLR4 complex recruits RIP1 (Homo sapiens)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Sus scrofa)


name: BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Bos taurus)


name: sulfur compound transmembrane transporter activity


name: IL24 binds to IL22RA1:JAK1:IL20RB (Sus scrofa)


name: a quinone + H(+) + NADH = a quinol + NAD(+)


name: Formation of the SCF-FBXL7 complex (Bos taurus)


name: Insertion of correct bases opposite the lesion by POLH (Canis familiaris)


name: Translocation of WWTR1 (TAZ) to the nucleus (Canis familiaris)


name: Binding of EGF to ligand-responsive EGFR mutants (Homo sapiens)


name: glutamate uptake by astrocytes (Danio rerio)


name: CoA + H(+) + O2 + pyruvate = acetyl-CoA + CO2 + H2O2


name: 2-hydroxybutanoyl-CoA + CO2 + succinate => 2-oxoglutarate + butanoyl-CoA + O2


name: PTGIR binds PTGIR agonists (Danio rerio)


name: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP


name: NEU1,4 hydrolyze PSAP(195-273):GM3:PE (Mus musculus)


name: griseophenone B + H(+) + O2 + reduced [NADPH--hemoprotein reductase] <=> desmethyl-dehydrogriseofulvin + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: p-4S, T366 ELK1:SRF bind EGR1 and EGR2 gene promoters (Homo sapiens)


name: (E)-ferulate + H(+) + S-adenosyl-L-homocysteine => (E)-caffeate + S-adenosyl-L-methionine


name: CBL binds and ubiquitinates phosphorylated Sprouty (Mus musculus)


name: benzylamine + H2O + NAD(+) <=> benzaldehyde + H(+) + NADH + NH4(+)


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Canis familiaris)


name: L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: type 1 melanin-concentrating hormone receptor binding


name: GNRHR binds GNRHR peptide agonists (Danio rerio)


name: H(+)(in) + tetracycline(out) => H(+)(out) + tetracycline(in)


name: H(+) + L-glyceraldehyde + NADPH => glycerol + NADP(+)


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Rattus norvegicus)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Bos taurus)


name: Aquaporin-1 passively transports water into cell (Plasmodium falciparum)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Rattus norvegicus)


name: (9Z,12Z)-hexadecadienoyl-CoA + AH2 + O2 <=> (9Z,12Z,15Z)-hexadecatrienoyl-CoA + A + 2 H2O


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Rattus norvegicus)


name: CDC6 association with ORC(1-6) at replication origins (Schizosaccharomyces pombe)


name: H(+) + NADPH + prostaglandin D2-ethanolamide = 11beta-prostaglandin F2-ethanolamide + NADP(+)


name: XDH dehydrogenates xanthine to form urate (Homo sapiens)


name: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH = 7alpha-hydroxy-5beta-cholestan-3-one + NADP(+)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Danio rerio)


name: dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Xenopus tropicalis)


name: AFG3L2 binds mitochondrial inner membrane proteins (Drosophila melanogaster)


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Caenorhabditis elegans)


name: Ubiquitination of phospho-p27/p21 (Danio rerio)


name: AUF1 binds translation and heat shock proteins (Rattus norvegicus)


name: L-tryptophan = (E)-3-(indol-3-yl)acrylate + NH4(+)


name: Activated NTRK3 promotes SRC autophosphorylation (Canis familiaris)


name: cis-beta-D-glucosyl-2-hydroxycinnamate + H2O => beta-D-glucose + cis-2-coumarate


name: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + H2O <=> (R)-glycerate + D-glucose


name: 6-hydroxy-3,7-dimethyloctanoate + H(+) => 7-isopropyl-4-methyloxepan-2-one + H2O


name: (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein] => dodecanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: SUMOylation of ING2 with SUMO1 (Mus musculus)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Canis familiaris)


name: ERBB4 forms heterodimers with EGFR (Mus musculus)


name: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate


name: p-CBL:GRB2 binds p-FRS2:activated FGFR2 (Sus scrofa)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Drosophila melanogaster)


name: (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+) => (R)-lanthionine ketimine + 2 H(+) + NADPH


name: (4R)-hydroxysphinganine + docosanoyl-CoA => CoA + H(+) + N-docosanoyl-(4R)-hydroxysphinganine


name: a plastoquinol + 2 H(+)(in) + 2 oxidized [plastocyanin] <=> a plastoquinone + 4 H(+)(out) + 2 reduced [plastocyanin]


name: (9Z)-octadecenoate + (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + H(+) => (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O


name: acetyl-CoA + octanoyl-CoA <=> 3-oxodecanoyl-CoA + CoA


name: H2O + O-phospho-D-serine => D-serine + phosphate


name: SUMOylation of TFAP2C with SUMO1 (Xenopus tropicalis)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH => (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: Resumption of elongation after recovery from pausing (Xenopus tropicalis)


name: CYP3A4 monooxygenates ATVL to 4-OH-ATVL (Xenopus tropicalis)


name: ATP + cycloheximide(in) + H2O <=> ADP + cycloheximide(out) + H(+) + phosphate


name: ADP + H(+) + O-phospho-L-threonine => ATP + L-threonine


name: E2F1/E2F2/E2F3 and SP1 stimulate transcription of p14ARF mRNA (Homo sapiens)


name: ABCC4 accumulation of dense granule contents (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) <=> 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + a 1,2-diacyl-sn-glycerol


name: Fibrillin microfibril assembly (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + sesquisabinene A


name: glycine + tetradecanoyl-CoA => CoA + H(+) + N-tetradecanoylglycine


name: (2E)-glutaconyl-CoA + H2O => (S)-3-hydroxyglutaryl-CoA


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine <=> a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP


name: cis-stilbene oxide + H2O = (1R,2R)-hydrobenzoin


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Danio rerio)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)


name: PIAS2-2 SUMOylates SUZ12 with SUMO1 (Homo sapiens)


name: gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity


name: AMP + diphosphate + L-cysteinyl-tRNA(Cys) => ATP + L-cysteine + tRNA(Cys)


name: H2O + L-valine + NADP(+) = 3-methyl-2-oxobutanoate + H(+) + NADPH + NH4(+)


name: 1-O-(trans-4-coumaroyl)-beta-D-glucose + cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) betaine = beta-D-glucose + cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside] + H(+)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Danio rerio)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + a ganglioside GM1b <=> adenosine 3',5'-bisphosphate + an 8-O-sulfo-ganglioside GM1b + H(+)


name: MTRR reduces cob(II)alamin to meCbl (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: erythromycin C + H2O + NADP(+) => erythromycin D + H(+) + NADPH + O2


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Homo sapiens)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Schizosaccharomyces pombe)


name: Free APC/C phosphorylated by Plk1 (Mus musculus)


name: Type II receptor phosphorylates type I receptor (Sus scrofa)


name: glycine betaine + H(+) + 2 H2O2 => choline + H2O + 2 O2


name: nsp12 binds nsp7 and nsp8 (Homo sapiens)


name: Activation of Rap1 by membrane-associated GEFs (Sus scrofa)


name: AS3MT transfers CH3 from AdoMet to arsenite(3-) (Sus scrofa)


name: 3-methyl-2-oxobutanoate(in) + H(+)(in) => 3-methyl-2-oxobutanoate(out) + H(+)(out)


name: ATP + beta-alanine + L-ornithine => ADP + beta-alanyl-L-ornithine + H(+) + phosphate


name: a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine


name: RHOH binds effectors at the plasma membrane (Rattus norvegicus)


name: Relocalization of nuclearly localized Cyclin D1 to the cytoplasm (Danio rerio)


name: RNASEs bind bacterial phospholipids (Sus scrofa)


name: PNP trimer transforms RBV to T-CONH2 (Homo sapiens)


name: H2O + N-(acetyl)-sphing-4-enine <=> acetate + sphing-4-enine


name: GTP + L-lysyl-[protein] => diphosphate + H(+) + N(epsilon)-GMP-L-lysyl-[protein]


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Sus scrofa)


name: GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Mus musculus)


name: a 2'-deoxyadenosine in DNA + acetyl-CoA + AH2 + NH4(+) + O2 => A + a N(6)-methylcarbamoyl-2'-deoxyadenosine in DNA + CoA + H(+) + 2 H2O


name: 2-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate => 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O


name: KRAB-ZNF / KAP Interaction (Homo sapiens)


name: NQO1 interaction with ODC (Rattus norvegicus)


name: a purine 2'-deoxyribonucleoside 5'-phosphate + H2O <=> 2-deoxy-D-ribose 5-phosphate + a purine nucleobase


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Canis familiaris)


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Sus scrofa)


name: H(+)(out) + K(+)(in) + L-aspartate(out) + 3 Na(+)(out) => H(+)(in) + K(+)(out) + L-aspartate(in) + 3 Na(+)(in)


name: NEK9 phosphorylates NEK6/NEK7 (Gallus gallus)


name: p-T68-CHEK2 autophosphorylates (Xenopus tropicalis)


name: RHOF GAPs stimulate RHOF GTPase activity (Bos taurus)


name: L-aspartate(out) + L-tyrosine(in) => L-aspartate(in) + L-tyrosine(out)


name: cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity


name: beta-ylangene + diphosphate => (2E,6E)-farnesyl diphosphate


name: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) => a 3-oxosteroid + CO2 + NADH


name: P2X1-mediated entry of Ca++ from plasma (Xenopus tropicalis)


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Sus scrofa)


name: Nephrin dimer:KIRREL binds FYN (Drosophila melanogaster)


name: KIBRA (WWC1) binds LATS proteins (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O <=> (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+)


name: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate


name: 4-methylquinoline + A + H2O => 4-methylquinolin-2(1H)-one + AH2


name: a 3-acyl-sn-glycerol + a fatty acid + H(+) => a 2,3-diacyl-sn-glycerol + H2O


name: (E)-4-coumaroyl-CoA + H2O = 3-hydroxy-3-(4-hydroxyphenyl)propanoyl-CoA


name: PGLYRP2 binds bacterial peptidoglycan (Canis familiaris)


name: Activation of conventional Protein Kinase C (Saccharomyces cerevisiae)


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Caenorhabditis elegans)


name: CYP17A1 17-hydroxylates PREG (Sus scrofa)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Drosophila melanogaster)


name: Caspase-mediated cleavage of PKC theta (Mus musculus)


name: a beta-D-glucuronoside + H2O <=> an alcohol + D-glucuronate


name: 4-prenylphlormethylbutanophenone + dimethylallyl diphosphate <=> deoxyadlupulone + diphosphate


name: HTR1 and 5A receptors can bind serotonin (Bos taurus)


name: solasodine + UDP-alpha-D-glucose => H(+) + solasodine 3-beta-D-glucoside + UDP


name: GLA hydrolyzes PSAP(195-273):Gb3Cer:PE (Bos taurus)


name: factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Gallus gallus)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Danio rerio)


name: NLK phosphorylates TCF/LEF (Homo sapiens)


name: IRAK1 phosphorylates Pellino (Drosophila melanogaster)


name: Fe(III)-di(C-5-deoxy-beta-D-glucosyl)-enterobactin + H2O => Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+)


name: MYC positively regulates MAPKAPK5 gene expression (Homo sapiens)


name: acetate + L-citrulline => H2O + N(2)-acetyl-L-citrulline


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + pentadecanoyl-CoA => 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA


name: Pellino binds hp-IRAK1:TRAF6 (Rattus norvegicus)


name: glyoxylate + H2O + pentanoyl-CoA => 3-propylmalate + CoA + H(+)


name: Formation of the 43S pre-initiation complex (Rattus norvegicus)


name: Formation of Processive Complex on the C-strand of the telomere (Bos taurus)


name: Active ARF recruits coatomer (Danio rerio)


name: Co-precorrin-4 + S-adenosyl-L-methionine = Co-precorrin-5A + H(+) + S-adenosyl-L-homocysteine


name: H2O + isomaltose => beta-D-glucose + D-glucose


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Canis familiaris)


name: maltose + H2O => 2 D-glucose (sucrase-isomaltase) (Gallus gallus)


name: an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP-alpha-D-glucose = an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside + H(+) + UDP


name: p62 binds ubiquitinated mitochondrial substrates (Rattus norvegicus)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Danio rerio)


name: D-phenylalanyl-tRNA(Phe) + H2O => D-phenylalanine + H(+) + tRNA(Phe)


name: SUMOylation of DNMT3B with SUMO1 (Mus musculus)


name: ADP + glycochenodeoxycholate(out) + H(+) + phosphate => ATP + glycochenodeoxycholate(in) + H2O


name: NPM1 binds TFAP2A homodimer (Rattus norvegicus)


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Homo sapiens)


name: USP12, USP26 deubiquitinate AR (Homo sapiens)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: coelenterazine h + O2 <=> CO2 + excited coelenteramide h monoanion + H(+) + hnu


name: dodecanal + H2O + O2 <=> dodecanoate + H(+) + H2O2


name: (13S)-vitexifolin A + diphosphate => 9alpha-copalyl diphosphate + H2O


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Caenorhabditis elegans)


name: 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate <=> (2S)-3-sulfolactaldehyde + pyruvate


name: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate


name: Caspase-8 cleaves IL1B precursor (Homo sapiens)


name: PARP1 binds SMAD2/3:SMAD4 heterotrimer (Sus scrofa)


name: CMP-N-acetylneuraminate transmembrane transporter activity


name: CTP(in) + dCMP(out) => CTP(out) + dCMP(in)


name: di-trans,octa-cis-undecaprenyl diphosphate + H2O => di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoyl-CoA + O2 = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + holo-[ACP] => a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-[ACP]


name: D-glucose(out) + H(+)(in) = D-glucose(in) + H(+)(out)


name: MAT1A multimers transfer Ado from ATP to L-Met (Rattus norvegicus)


name: Caspase-mediated cleavage of FADK 1 (Rattus norvegicus)


name: [translation elongation factor 2] + ATP = [translation elongation factor 2]-phosphate + ADP + H(+)


name: dephospho-[reductase kinase] kinase activity


name: BRCA1-A complex deubiquitinates K63polyUb-histone H2A (Mus musculus)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate = 5-oxo-(6E,8Z,11Z,14Z)-eicosatetraenoate + H2O


name: carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)


name: DDIT4 binds 14-3-3 dimer (Xenopus tropicalis)


name: 2,3-dihydrobiochanin A + NADP(+) <=> biochanin A + 2 H(+) + NADPH


name: ABCAs mediate lipid influx (Homo sapiens)


name: GDIs block activation of RHOB (Mus musculus)


name: PP2A dephosphorylates inactive RAFs (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Schizosaccharomyces pombe)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Sus scrofa)


name: UDP-alpha-D-galactose(in) + UDP-alpha-D-glucose(out) <=> UDP-alpha-D-galactose(out) + UDP-alpha-D-glucose(in)


name: ATP + biotin + CoA = AMP + biotinyl-CoA + diphosphate


name: propanoyl-CoA + tetradecanoyl-CoA => 3-oxo-2-methylhexadecanoyl-CoA + CoA


name: (9Z,12Z)-octadecadienoate + O2 <=> (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: chloride(out) + iodide(in) => chloride(in) + iodide(out)


name: bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer (Sus scrofa)


name: 1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol <=> an alkyl cinnamate + beta-D-glucose


name: tri-trans,hepta-cis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UMP


name: CoA + H(+) + N-acetyl-S-methyl-L-cysteine => acetyl-CoA + S-methyl-L-cysteine


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Mus musculus)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho]-glycerol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol


name: ADP-alpha-D-glucose + sn-glycerol 3-phosphate => 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + ADP + H(+)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Homo sapiens)


name: acetyl-CoA + H2O => acetate + CoASH (Caenorhabditis elegans)


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + a 1,2-diacyl-sn-glycerol => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli)


name: (S)-2-hydroxyglutarate + FAD + H(+) = 2-oxoglutarate + FADH2


name: Association of Cdh1 with the APC/C (Homo sapiens)


name: p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 (Homo sapiens)


name: "enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)"


name: 6-demethylmitomycin B + S-adenosyl-L-methionine = mitomycin B + S-adenosyl-L-homocysteine


name: AMP + diphosphate + L-methionyl-tRNA(Met) => ATP + L-methionine + tRNA(Met)


name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Rattus norvegicus)


name: Release of PLCG from FCGR (Canis familiaris)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H2O <=> a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + D-galactose


name: L-glutamate(in) + 2 Na(+)(in) = L-glutamate(out) + 2 Na(+)(out)


name: 2 mycothiol + NAD(+) <=> H(+) + mycothione + NADH


name: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO2


name: Phosphorylated STAT1, STAT3 form dimers (Sus scrofa)


name: a 3-oxo-fatty acyl-CoA + H(+) + NADPH => a 3-hydroxy-fatty acyl-CoA + NADP(+)


name: Interaction of MyoD:E protein with MEF2 (Mus musculus)


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Canis familiaris)


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-acetyl-4'-phosphopantetheine => acetyl-CoA + H2O


name: 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine = 4',7-dihydroxy-3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Xenopus tropicalis)


name: Formation of DRIP coactivator complex (Gallus gallus)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)


name: a cholesterol ester + H2O => a fatty acid + cholesterol + H(+)


name: D-glucose + sn-glycerol 3-phosphate => D-glucose 6-phosphate + glycerol


name: GTP + N-acetyl-D-glucosamine => GDP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: A + dihydropyriculariol = AH2 + pyriculariol


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Mus musculus)


name: Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm (Canis familiaris)


name: NPC2 transfers CHOL to NPC1 (Caenorhabditis elegans)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: CO + H(+) + N-formylanthranilate => 3-hydroxy-1H-quinolin-4-one + O2


name: RAC3 binds effectors at the plasma membrane (Caenorhabditis elegans)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Mus musculus)


name: glutarate(out) + prostaglandin F2alpha(in) => glutarate(in) + prostaglandin F2alpha(out)


name: GTP-binding activates eEF2 (Mus musculus)


name: (S)-6-hydroxynicotine + O2 => 6-hydroxy-N-methylmyosmine + H2O2


name: 4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity


name: pyridine + thiamine => 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine


name: beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] (Homo sapiens)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Drosophila melanogaster)


name: PC is converted to PS by PTDSS1 (Plasmodium falciparum)


name: 1,2-di(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+) => 1,2-di-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho-1D-myo-inositol + ATP


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Bos taurus)


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Danio rerio)


name: asperterpenoid A + O2 + reduced [NADPH--hemoprotein reductase] = asperterpenoid C + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: calcium-activated potassium channel activity


name: H(+)(in) + L-lyxopyranose(in) => H(+)(out) + L-lyxopyranose(out)


name: CO2 + L-lyxonate => 2-carboxy-L-lyxonate + H(+)


name: Connexin 36 mediated neuronal gap junction communication (Canis familiaris)


name: D-ribulose 5-phosphate <=> ribose 5-phosphate (Sus scrofa)


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Saccharomyces cerevisiae)


name: Phosphorylated HPO dimer phosphorylates WTS (Drosophila melanogaster)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Dictyostelium discoideum)


name: transcription regulatory region nucleic acid binding


name: Crizotinib-driven IL10RA gene expression in NPM1-ALK (Homo sapiens)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Sus scrofa)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADPH <=> all-trans-lycopaoctaene + 2 diphosphate + NADP(+)


name: butanoate + glycerol + H(+) => 1-butyrylglycerol + H2O


name: adenosine 3',5'-bisphosphate + firefly D-sulfoluciferin + H(+) => 3'-phosphoadenylyl sulfate + firefly D-luciferin


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Schizosaccharomyces pombe)


name: (S)-2,3-diaminopropanoate + 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + ATP <=> 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + AMP + diphosphate


name: epoxypheophorbide a + H2O <=> H(+) + red chlorophyll catabolite


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Dictyostelium discoideum)


name: 3-methylbutanal + H2O + NADP(+) => 3-methylbutanoate + 2 H(+) + NADPH


name: p-4Y-PLCG1 dissociates from activated FGFR3 (Danio rerio)


name: HSD17B11 dehydrogenates EST17b to E1 (Homo sapiens)


name: ADIPOQ trimer binds ADIPOR dimers (Canis familiaris)


name: Fumarate + H2O <=> (S)-Malate (Drosophila melanogaster)


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Danio rerio)


name: Factor IIa inhibitors (compounds) binds IIa (Mus musculus)


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Mus musculus)


name: STING ubiquitination by TRIM32 or TRIM56 (Sus scrofa)


name: Factor B binds to C3(H2O) (Gallus gallus)


name: MEN1 binds SMAD2/3:SMAD4 heterotrimer (Rattus norvegicus)


name: (R)-metanephrine + H(+) + S-adenosyl-L-homocysteine => (R)-normetanephrine + S-adenosyl-L-methionine


name: PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body (Rattus norvegicus)


name: glutathione + glutathioselenol + NADP(+) => H(+) + NADPH + selenodiglutathione


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Bos taurus)


name: JMY, TTC5 and EP300 bind (Rattus norvegicus)


name: ATP-dependent DNA (cytosine-5-)-methyltransferase activity


name: a 2'-deoxycytidine in DNA + ATP + H2O + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + ADP + 2 H(+) + phosphate + S-adenosyl-L-homocysteine


name: a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) <=> a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: (8S)-8-amino-7-oxononanoate + CO2 + L-lysyl-[protein] = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 2 H(+)


name: (S)-2-amino-6-oxohexanoate + H2O + NAD(+) => 2 H(+) + L-2-aminoadipate + NADH


name: 2-methylbutanamine + H2O + NADP(+) => 2-methylbutanal + H(+) + NADPH + NH4(+)


name: H(+)(out) + L-leucyl-L-leucine(out) => H(+)(in) + L-leucyl-L-leucine(in)


name: 6-deoxy-6-sulfo-D-fructose 1-phosphate = (2S)-3-sulfolactaldehyde + dihydroxyacetone phosphate


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Rattus norvegicus)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Dictyostelium discoideum)


name: The Kiss receptor GPR54 binds kisspeptin (Bos taurus)


name: ITPA hydrolyses ITP to IMP (Drosophila melanogaster)


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Danio rerio)


name: (2R)-2,3-bisphosphoglycerate + ATP + H(+) <=> ADP + cyclic (2R)-2,3-bisphosphoglycerate + phosphate


name: IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Bos taurus)


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a 1-acyl-sn-glycero-3-phosphocholine <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine


name: Fibrillin C-terminal processing (Mus musculus)


name: (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate => (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate


name: a 4,5-didehydrojasmonate + H(+) + NADPH = a jasmonate + NADP(+)


name: 2-methyl-3-oxopropanoate + L-glutamate => (S)-3-amino-2-methylpropanoate + 2-oxoglutarate


name: (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase] = 3beta-hydroxycostunolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O2 + L-lysyl-[collagen] + L-methionyl-[collagen] = [collagen]-L-lysyl-N-S-L-methionyl-[collagen] + H(+) + 2 H2O


name: D-gluconate + FAD + H(+) = 2-dehydro-D-gluconate + FADH2


name: Synthesis of dolichyl-phosphate-glucose (Schizosaccharomyces pombe)


name: "Hydron translocation linked to the hydrolysis of a nucleoside triphosphate"


name: SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate (Homo sapiens)


name: glycyl-L-leucine(out) + 2 H(+)(out) = glycyl-L-leucine + 2 H(+)(in)


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Saccharomyces cerevisiae)


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Schizosaccharomyces pombe)


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Canis familiaris)


name: Association of mTERF with the termination sequence (Drosophila melanogaster)


name: (2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-[protein] <=> 2'-deoxyribonucleotide-DNA + H(+) + S-methyl-L-cysteinyl-[protein]


name: F mRNA is translated into nascent protein F (Homo sapiens)


name: miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2 H(+) + 3 H2O + miltiradien-20-al + 2 oxidized [NADPH--hemoprotein reductase]


name: 5-fluorouridine + ATP <=> 5-fluorouridine 5'-phosphate + ADP + H(+)


name: 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity


name: asperaculane E + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => aculene D + CO2 + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: WLS:WNT complex is internalized for maturation into exosomes (Drosophila melanogaster)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Dictyostelium discoideum)


name: PKC-delta phosphorylates CARD9 (Sus scrofa)


name: alpha-D-glucose 6-phosphate <=> beta-D-glucose 6-phosphate


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione <=> (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: 18-hydroxy-(9R,10S)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9R,10S)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: EGFR autophosphorylation (Drosophila melanogaster)


name: Rad51 assembly at the DNA-damage sites on the chromatin (Gallus gallus)


name: Autocatalytic phosphorylation of FGFR1c (Drosophila melanogaster)


name: Na(+)(out) + nicotinate(out) <=> Na(+)(in) + nicotinate(in)


name: Transfer of ISG15 from E1 to E2 (UBCH8) (Caenorhabditis elegans)


name: Basigin binds MCT1, MCT3 and MCT4 (Xenopus tropicalis)


name: H(+) + hexadecanoate + NADPH + O2 = 14-hydroxyhexadecanoate + H2O + NADP(+)


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)


name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region (Rattus norvegicus)


name: 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O => 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + phosphate


name: a flavonol 3-O-glycoside + UDP-alpha-D-xylose => a flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside] + H(+) + UDP


name: GOPC promotes translocation of CFTR to lysosomes (Rattus norvegicus)


name: H2O + Met-enkephalin-Arg-Phe <=> L-arginyl-L-phenylalanine + Met-enkephalin


name: Necl-1:Nectin 3 trans heterodimer interaction (Bos taurus)


name: H(+) + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + UDP => myricetin 3-O-alpha-L-rhamnoside + UDP-alpha-D-glucose


name: Formation of anchoring fibrils (Xenopus tropicalis)


name: BESTs transport cytosolic HCO3- to extracellular region (Canis familiaris)


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Drosophila melanogaster)


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Canis familiaris)


name: Activation of cytosolic AMPK by phosphorylation (Canis familiaris)


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Saccharomyces cerevisiae)


name: TFIIH binds GG-NER site to form a verification complex (Drosophila melanogaster)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(36-hydroxyhexatriacontadienoyl)-sphing-4-enine = a diacylglycerol + an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontadienoyl)-sphing-4-enine


name: (+)-dehydrodiconiferyl acid + a quinone <=> (+)-dehydrodiconiferyl acid ketone + a quinol


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Canis familiaris)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Plasmodium falciparum)


name: HM13 cleaves HMOX1 dimer (Drosophila melanogaster)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Canis familiaris)


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Canis familiaris)


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Gallus gallus)


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Rattus norvegicus)


name: anthraniloyl-CoA + 2 H(+) + 2 NADH + O2 <=> 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NAD(+)


name: Surface deployment of platelet alpha granule membrane components (Xenopus tropicalis)


name: 1D-myo-inositol 1,4-bisphosphate + phosphate => 1D-myo-inositol 1,4,5-trisphosphate + H2O


name: 1-O-decyl-(9Z)-octadecenoate + CoA => (9Z)-octadecenoyl-CoA + decan-1-ol


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Plasmodium falciparum)


name: K63polyUb-IRAK1 dissociates (Canis familiaris)


name: (E)-coniferyl acetate + NADPH => acetate + eugenol + NADP(+)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Dictyostelium discoideum)


name: UBA1 adenylates ubiquitin in the nucleoplasm (Canis familiaris)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Canis familiaris)


name: YOD1 binds VCP (Dictyostelium discoideum)


name: BMP2 binds to the receptor complex (Sus scrofa)


name: L-glutamine + UDP-3-oxo-alpha-D-glucose = 2-oxoglutaramate + UDP-alpha-D-kanosamine


name: SMUG1 glycosylase mediated recognition and binding of uracil in DNA (Homo sapiens)


name: diphosphate + stellata-2,6,19-triene => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: Formation of hydroxyallysine by LOX (Gallus gallus)


name: (E)-coniferol + NADP(+) <=> (E)-coniferaldehyde + H(+) + NADPH


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 12-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoadipate + acetyl-CoA + H2O => (R)-dihomocitrate + CoA + H(+)


name: (17Z)-hexacosenoyl-CoA + sphinganine <=> CoA + H(+) + N-[(17Z)-hexacosenoyl]dihydrosphingosine


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Xenopus tropicalis)


name: Beclin-1 complex phosphorylates PtdIns (Bos taurus)


name: 6alpha-hydroxytyphasterol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + typhasterol


name: 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Homo sapiens)


name: SMURF2 monoubiquitinates SMAD3 (Sus scrofa)


name: (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + H(+) + NADPH => (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + NADP(+)


name: NEMO subunit of IKK complex binds to activated IRAK1 (Homo sapiens)


name: a 27-hydroxysterol + UDP-alpha-D-glucose => a sterol 27-beta-D-glucoside + H(+) + UDP


name: CoA + O-hexanoyl-L-seryl-[protein] => hexanoyl-CoA + L-seryl-[protein]


name: (5Z)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Rattus norvegicus)


name: KCTD15 binds TFAP2 homo- and heterodimers (Homo sapiens)


name: TAK1 is activated within the TAK1 complex (Mus musculus)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Canis familiaris)


name: CTDNEP1:CNEP1R1 dephosphorylates LPIN (Drosophila melanogaster)


name: ATP + hygromycin B <=> 7''-O-phosphohygromycin B + ADP + H(+)


name: H2O + O2 + urate => 5-hydroxyisourate + H2O2


name: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+)


name: Recruitment of p190RhoGEF to p-FAK (Mus musculus)


name: (3S)-versiconol acetate + NADP(+) = (2S,3S)-versiconal hemiacetal acetate + H(+) + NADPH


name: CO2 + formaldehyde + neomorphinone + succinate => 2-oxoglutarate + O2 + oripavine


name: (15S)-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate => (8Z,11Z,14Z)-eicosatrienoate + O2


name: 4-(gamma-L-glutamylamino)butanoate + H2O => 4-aminobutanoate + L-glutamate


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Canis familiaris)


name: 2-hydroxybenzoyl-CoA + malonyl-CoA <=> 4-hydroxycoumarin + CO2 + 2 CoA


name: Formation of RAD50:MRE11 complex (Saccharomyces cerevisiae)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Drosophila melanogaster)


name: L-glutamine(out) + L-serine(in) + Na(+)(in) => L-glutamine(in) + L-serine(out) + Na(+)(out)


name: Association of Golgi  transport vesicles with microtubules (Mus musculus)


name: uridine(38/39/40) in tRNA <=> pseudouridine(38/39/40) in tRNA


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Mus musculus)


name: Transport (influx) of bile salts and acids by OATP-A (Homo sapiens)


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Gallus gallus)


name: Light stimulates opsin receptors (Rattus norvegicus)


name: L-aspartate + menaquinone-8 => iminosuccinate + menaquinol-8


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-hexadecanoylglycerol = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z)-octadecenoyl-2-hexadecanoylglycerol


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Mus musculus)


name: InlB:MET dimer trans-autophophorylates (Homo sapiens)


name: 2-hydroxy-3-methylhexadecanoyl-CoA => 2-methylpentadecanal + formyl-CoA


name: PTK2 autophosphorylates (Canis familiaris)


name: H2O + N-(9Z-octadecenoyl)-L-tryptophan <=> (9Z)-octadecenoate + L-tryptophan


name: 2-oxobutanoate + acetyl-CoA + H2O <=> (R)-2-ethylmalate + CoA + H(+)


name: Degradation of ubiquitinated SMAD3 (Drosophila melanogaster)


name: CDT1 gene expression is stimulated by E2F1 (Homo sapiens)


name: 1-acyl LPG is acylated to PG by LPGAT (Homo sapiens)


name: luteolin + UDP-alpha-D-glucuronate => H(+) + luteolin 7-O-beta-D-glucuronide + UDP


name: PIAS2,3,4 SUMOylate RORA with SUMO1 (Caenorhabditis elegans)


name: H2O + N-dodecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-dodecanoylethanolamine


name: Luteinizing hormone receptor can bind LH (Sus scrofa)


name: ATP + H2O + putrescine(out) <=> ADP + H(+) + phosphate + putrescine(in)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Gallus gallus)


name: STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Canis familiaris)


name: H2O + N-formyl-L-methionine <=> formate + L-methionine


name: Interaction of Nectins with Afadin (Caenorhabditis elegans)


name: Association of INK4 family proteins with CDK4/6 (Rattus norvegicus)


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + succinate


name: guanyl-nucleotide exchange factor activity


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Canis familiaris)


name: 1-acyl LPC is acylated to PC by LPCAT (Canis familiaris)


name: a quinone + butan-1-ol => a quinol + butanal


name: Activated DINR binds Chico (Drosophila melanogaster)


name: (R)-lavandulyl diphosphate + H2O = (R)-lavandulol + diphosphate


name: a sphingomyelin + H2O <=> an N-acylsphing-4-enine 1-phosphate + choline + H(+)


name: (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,12Z,15Z)-hexadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Mus musculus)


name: VAV1 is a GEF for Rho/Rac family GTPases (Rattus norvegicus)


name: PRKCB (PKC-beta) phosphorylates CARMA1 (Canis familiaris)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Rattus norvegicus)


name: (9Z)-octadecenoate + 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) => 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + H2O


name: Activation of NLK (Drosophila melanogaster)


name: H(+)(in) + N-(4-aminobenzoyl)-L-glutamate(in) => H(+)(out) + N-(4-aminobenzoyl)-L-glutamate(out)


name: 3-oxodecanoyl-CoA + CoA => acetyl-CoA + octanoyl-CoA


name: NAGLU hydrolyses heparan chain(2) (Dictyostelium discoideum)


name: USP13 and OTUD3 deubiquitinate PTEN (Rattus norvegicus)


name: Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Bos taurus)


name: ATP + H(+) + NADPH + octanoate = AMP + diphosphate + NADP(+) + octanal


name: carnosine(in) + n H(+)(in) => carnosine(out) + n H(+)(out)


name: LPL hydrolyses TGs from mature CMs (Bos taurus)


name: RSV F binds TLR4:LY96:CD14 (Homo sapiens)


name: an alk-2-enal + H(+) + NADH => an n-alkanal + NAD(+)


name: PKN1 stimulates association of AR with NCOA2 (Mus musculus)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: CMP-N-acetyl-beta-neuraminate + N-acetyl-beta-lactosamine <=> CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine


name: GDP is exchanged for GTP on DRheb (Drosophila melanogaster)


name: BRAF autophosphorylates downstream of RAP1 and NGF (Rattus norvegicus)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Rattus norvegicus)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Canis familiaris)


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Canis familiaris)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Schizosaccharomyces pombe)


name: L-arginine + L-cysteinyl-[NO transferase protein] + NADPH + 2 O2 <=> 2 H2O + L-citrulline + NADP(+) + S-nitroso-L-cysteinyl-[NO transferase protein]


name: PLK3 phosphorylates CDC25C (Homo sapiens)


name: Formation of the MCC complex (Sus scrofa)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Xenopus tropicalis)


name: ERCC5 and RPA bind TC-NER site (Mus musculus)


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Mus musculus)


name: ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (Xenopus tropicalis)


name: Ubiquitinated Cdc6 is degraded by the proteasome (Homo sapiens)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA


name: chloride + FADH2 + L-tryptophan + O2 <=> 7-chloro-L-tryptophan + FAD + 2 H2O


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Canis familiaris)


name: (Z)-1,2-dichloroethene + AH2 => A + chloride + chloroethene + H(+)


name: SALMs 1-3 bind to PSD-95 family members (Rattus norvegicus)


name: a 2-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H(+) + sn-glycerol 3-phosphocholine


name: a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)


name: NSF and SNAPs bind cis-SNARE complex (Bos taurus)


name: NT5C2 tetramer dephosphorylates RBV-MP (Canis familiaris)


name: an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin]


name: botC HC:LC binds GT1b on the target cell surface (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + homogentisate = 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate


name: Translocation of CaN:CaM:NFAT to nucleus (Sus scrofa)


name: a 1,3-diacyl-sn-glycerol + CoA => a 1-acyl-sn-glycerol + an acyl-CoA


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Caenorhabditis elegans)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Rattus norvegicus)


name: MYSM1 deubiquitinates Histone H2A (Caenorhabditis elegans)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Danio rerio)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycerol + H(+)


name: 16:0 monogalactosyldiacylglycerol desaturase activity


name: 2-oxoglutarate + L-histidyl-[ankyrin-repeat domain protein] + O2 <=> (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Xenopus tropicalis)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Homo sapiens)


name: PP1 dephosphorylates TGFBR1 (Homo sapiens)


name: Collagen type XVIII endostatin release (Mus musculus)


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O


name: AMP(out) + CMP-N-acetyl-beta-neuraminate(in) => AMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: acetate(out) + H(+)(out) = acetate(in) + H(+)(in)


name: IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Gallus gallus)


name: 3-methyl-(2E)-butenoyl-CoA + ATP + hydrogencarbonate = 3-methyl-(2E)-glutaconyl-CoA + ADP + H(+) + phosphate


name: Formation of the IGF:IGFBP3:ALS complex (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine => 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+) => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 24 H(+) + 8 malonyl-CoA + 16 NADPH


name: Caspase-mediated cleavage of Etk (Bos taurus)


name: Active calmodulin binds CAMK2 (Mus musculus)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: broad specificity oxidative DNA demethylase activity


name: (2S,3R)-capreomycidine + H2O => (2S,3S)-hydroxyarginine


name: 2-chloro-N-isopropylacetanilide reductive dehalogenase activity


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Rattus norvegicus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H(+) + phosphocholine


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Rattus norvegicus)


name: acetyl-CoA + L-serine => CoA + O-acetyl-L-serine


name: Recruitment of Dna2 endonuclease (Canis familiaris)


name: (3S)-hydroxy-3-methylglutaryl-[ACP] + H(+) + holo-[ACP] => 3-oxobutanoyl-[ACP] + acetyl-[ACP] + H2O


name: Phosphorylated STAT92E dimer transports from the cytosol to the nucleus (Drosophila melanogaster)


name: H2O + L-alanine + O2 => H2O2 + NH4(+) + pyruvate


name: 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + 6 CO2 + 7 CoA + H2O => acetyl-CoA + 5 H(+) + 6 malonyl-CoA


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Schizosaccharomyces pombe)


name: 3,3',5-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) => 3,3',5-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: L-cysteine => 2-aminoprop-2-enoate + H(+) + hydrogen sulfide


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: ERCC8 (CSA) binds stalled RNA Pol II (Drosophila melanogaster)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Homo sapiens)


name: L-threonate + NAD(+) <=> 2-dehydro-L-erythronate + H(+) + NADH


name: Abortive Initiation After Second Transition (Drosophila melanogaster)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Mus musculus)


name: oxalate + oxidized 2[4Fe-4S]-[ferredoxin] => 2 CO2 + reduced 2[4Fe-4S]-[ferredoxin]


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1) = beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3)


name: H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + oxytetracycline => 5a,11a-dehydrooxytetracycline + reduced coenzyme F420-(gamma-L-Glu)(n)


name: RAC2 binds effectors at the phagocytic vesicle membrane (Mus musculus)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Homo sapiens)


name: 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Thr-[protein] + CMP-N-acetyl-beta-neuraminate => 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-Thr-[protein] + CMP + H(+)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Saccharomyces cerevisiae)


name: chlorophyllide a + H(+) + phytyl diphosphate => chlorophyll a + diphosphate


name: (E)-isoeugenol + S-adenosyl-L-methionine <=> (E)-isomethyleugenol + H(+) + S-adenosyl-L-homocysteine


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Mus musculus)


name: (+)-sesamin + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) => (+)-sesamin monocatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n)


name: PTGS2 dimer binds PTGS2 inhibitors (Danio rerio)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Homo sapiens)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Bos taurus)


name: O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2 <=> 19-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Mus musculus)


name: site-specific DNA-methyltransferase (cytosine-N4-specific) activity


name: a 3alpha-hydroxysteroid + NADP(+) = a 3-oxosteroid + H(+) + NADPH


name: an alkyl cinnamate + beta-D-glucose => 1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Sus scrofa)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Bos taurus)


name: 2-aminobut-2-enoate + H2O => L-homoserine


name: 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH => isocholate + NAD(+)


name: Export of peptide loaded MHC class I complex to PM (Danio rerio)


name: The single sugars GlcA and GlcNAc translocate from the lysosome to the cytosol (Homo sapiens)


name: Plasma membrane glycoconjugates translocate to the cytosol (Homo sapiens)


name: p62 is recruited and forms a complex with TRAF6 (Gallus gallus)


name: AKR1C1 hydrogenates PREDN,PREDL (Sus scrofa)


name: H2O + S-benzyl-L-cysteinylglycine = glycine + S-benzyl-L-cysteine