name: [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + H(+) + UDP => [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Xenopus tropicalis)


name: SRC-1 phosphorylates PTK2-beta (Rattus norvegicus)


name: Loading of antigenic peptides (Sus scrofa)


name: L-arginine(out) + L-phenylalanine(in) => L-arginine(in) + L-phenylalanine(out)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Gallus gallus)


name: O2 + prosolanapyrone II => H2O2 + prosolanapyrone III


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Mus musculus)


name: NEIL1 cleaves FapyG from damaged DNA (Xenopus tropicalis)


name: GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH => GDP-beta-L-fucose + NADP(+)


name: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesol + diphosphate


name: Dicer cleaves pre-miRNA to yield duplex miRNA (Homo sapiens)


name: a 2-acylglycerol + H2O <=> a fatty acid + glycerol + H(+)


name: Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)


name: DHCR7 reduces 7-dehydroCHOL to CHOL (Canis familiaris)


name: (2E)-octadecenoyl-[ACP] + H(+) + NADPH <=> NADP(+) + octadecanoyl-[ACP]


name: CES3 hydrolyses CHEST to CHOL and LCFA(-) (Gallus gallus)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Mus musculus)


name: ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Bos taurus)


name: MAP2Ks phosphorylate MAPKs (Rattus norvegicus)


name: (+)-7-isojasmonate + L-isoleucine => H2O + L-isoleucine-(+)-7-isojasmonate


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Dictyostelium discoideum)


name: (2E,6E)-farnesyl diphosphate = calarene + diphosphate


name: RDH5 oxidises 11cROL to 11cRAL (Bos taurus)


name: PIR oxygenates quercetin (Rattus norvegicus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Sus scrofa)


name: (1R,4S)-1-hydroxylimonen-2-one + NADPH + O2 <=> (3S)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+)


name: GALK1 phosphorylates Gal to Gal1P (Bos taurus)


name: 2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity


name: Nociceptin receptor binds to nociceptin (Mus musculus)


name: SLC46A1 transports FOLA from extracellular region to cytosol (Sus scrofa)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + 2 UDP-alpha-D-glucose = 2 H(+) + ternatin C5 + 2 UDP


name: (2E,6E)-farnesyl diphosphate <=> (-)-germacrene D + diphosphate


name: IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Gallus gallus)


name: Activation of MMP9 intermediate form by MMPs (Homo sapiens)


name: 6-O-malonyl-rhaponticin + CoA => malonyl-CoA + rhaponticin


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Canis familiaris)


name: PP2A-PP2R5C dephosphorylates MDM2 (Homo sapiens)


name: ATP + H2O + hexadecanedioate(in) <=> ADP + H(+) + hexadecanedioate(out) + phosphate


name: G-protein beta-gamma subunits rebind the alpha-GDP subunit (Bos taurus)


name: 5,6-dihydrouridine(17) in tRNA + NAD(+) <=> H(+) + NADH + uridine(17) in tRNA


name: CO2 + spermidine => carboxyspermidine + H(+)


name: PGM2:Mg2+ isomerises R1P to R5P (Rattus norvegicus)


name: Binding of TFIIIC to Type 2 promoter (Homo sapiens)


name: Formation of the CTF18-RFC(7s) complex (Gallus gallus)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 => (13R)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: (2E,6E,10E)-geranylgeranyl diphosphate => (13E)-labda-7,13-dien-15-yl diphosphate


name: OGG1beta translocates to mitochondria (Saccharomyces cerevisiae)


name: Defective RBP4 does not bind atROL (Homo sapiens)


name: 3-hydroxypropanoate + NAD(+) <=> 3-oxopropanoate + H(+) + NADH


name: 2 ATP + 2 cob(II)inamide + reduced [electron-transfer flavoprotein] => 2 adenosylcob(III)inamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: (1S)-3-methyl-cyclohexylamine + H2O + NADP(+) => 3-methylcyclohexanone + H(+) + NADPH + NH4(+)


name: H(+) + N,N-dihydroxy-L-tyrosine <=> (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O


name: pseudouridine in 5S rRNA => uridine in 5S rRNA


name: PP2A dephosphorylates inactive RAFs (Sus scrofa)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Xenopus tropicalis)


name: I(1,4,5)P3 transports from the ER lumen to the cytosol (Homo sapiens)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Xenopus tropicalis)


name: Gamma-secretase cleaves YBX1:NOTCH3 (Xenopus tropicalis)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Bos taurus)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Xenopus tropicalis)


name: ATP + H2O + vincristine(in) = ADP + H(+) + phosphate + vincristine(out)


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Sus scrofa)


name: PAK1 phosphorylates LIMK1 (Drosophila melanogaster)


name: PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Sus scrofa)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Canis familiaris)


name: OCT2 mediates tubular secretion of organic cations in the kidney (Danio rerio)


name: 2,3-DKG hydrolyses to ERU and oxalate (Homo sapiens)


name: Cyclisation of GTP to precursor Z (Caenorhabditis elegans)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Dictyostelium discoideum)


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + H2O <=> a 5'-end phospho-adenosine in mRNA + 2 H(+) + N(7)-methyl-GDP


name: (R)-carnitinyl-CoA <=> crotonobetainyl-CoA + H2O


name: 2'-hydroxydaidzein + 2 H(+) + NADPH => 2'-hydroxy-2,3-dihydrodaidzein + NADP(+)


name: 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP <=> 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: ANKLE2 is deacetylated by SIRT2 (Danio rerio)


name: Clusterin binds C5b-C7, C8, C9 (Sus scrofa)


name: Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Bos taurus)


name: EPOR binds EPOR agonists (Drosophila melanogaster)


name: a primary amine + S-adenosyl-L-methionine <=> a methylated primary amine + H(+) + S-adenosyl-L-homocysteine


name: FAR1 reduces PalmCoA to HXOL (Drosophila melanogaster)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Rattus norvegicus)


name: L-histidyl-[protein] + NAD(+) => H(+) + N(tele)-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide


name: ALDH4A1 oxidises L-GluSS to Glu (Danio rerio)


name: Synthesis of GABA by GAD2 (Caenorhabditis elegans)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Schizosaccharomyces pombe)


name: Spermine  => N-acetylated spermine (Dictyostelium discoideum)


name: 6-deoxo-28-norcastasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 28-norcastasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: NSF ATPase activity dissociates cis-SNARE (Bos taurus)


name: Cortisol translocates from the mitochondrial matrix to the cytosol (Homo sapiens)


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Mus musculus)


name: L-glutamyl-[protein] + NAD(+) <=> 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide


name: H(+) + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP => N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 7-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Caenorhabditis elegans)


name: G13 activation by TP receptor (Mus musculus)


name: 5-aminomethyl-dUMP in DNA + AH2 + glyoxylate => 5-N(alpha)-glycyl-dTMP in DNA + A + H2O


name: AMP + H2O + W-molybdopterin cofactor => adenylyl-molybdopterin + H(+) + tungstate


name: L-threonyl-[protein] + N-acetyl-D-galactosamine => 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O


name: 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + CoA => a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + an acyl-CoA


name: ATP + N(6)-(D-fructosyl)-L-lysyl-[protein] = ADP + H(+) + N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein]


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Plasmodium falciparum)


name: Recruitment of VAV to p-SLP-76 (Rattus norvegicus)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + GTP => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + diphosphate + GMP


name: AGO2 cleaves passenger strand of duplex siRNA (Canis familiaris)


name: ATP + H(+) + tetradecanoate => diphosphate + tetradecanoyl-AMP


name: eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Homo sapiens)


name: a ribonucleoside 5'-diphosphate + dCMP + H(+) => 2'-deoxycytidine + a ribonucleoside 5'-triphosphate


name: benzoate + H(+) + NADH + O2 <=> (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: MATEs mediate extrusion of xenobiotics (Bos taurus)


name: AMP + diphosphate => 5-phospho-alpha-D-ribose 1-diphosphate + adenine


name: SFTPAs translocate from ER membrane to extracellular region (Gallus gallus)


name: 1-decanoylglycerol + H2O = decanoate + glycerol + H(+)


name: A + 2 ADP + H(+) + NH4(+) + 2 phosphate <=> AH2 + 2 ATP + H2O + hydroxylamine


name: Complexed PIWIL2:2'-O-methyl-piRNA cleaves transposon RNA (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate => beta-pinacene + diphosphate


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Homo sapiens)


name: single-subunit type RNA polymerase binding


name: alpha-D-glucose 6-phosphate => alpha-D-glucose 1-phosphate


name: allantoate + H2O <=> (S)-ureidoglycolate + urea


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Xenopus tropicalis)


name: D-allulose 6-phosphate <=> keto-D-fructose 6-phosphate


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Schizosaccharomyces pombe)


name: c-FOS activation by phospho ERK1/2 (Canis familiaris)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Danio rerio)


name: Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Xenopus tropicalis)


name: S-methyl-5-thio-D-ribulose 1-phosphate = 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = a fatty acid + beta-D-glucosyl-(1<->1)-sphing-4-enine


name: ATP + L-threonyl-[myosin heavy-chain] = ADP + H(+) + O-phospho-L-threonyl-[myosin heavy-chain]


name: 3-hydroxypyruvate + glycine => glyoxylate + L-serine


name: 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spheroidene = 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + spheroiden-2-one


name: a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Saccharomyces cerevisiae)


name: 26S proteasome degrades PolyUb-RUNX2 (Mus musculus)


name: Trimming of peptides in ER (Gallus gallus)


name: Phosphorylation of CBL (EGFR:CBL) (Gallus gallus)


name: Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Danio rerio)


name: HSD17B1 hydrogenates E1 to EST17b (Rattus norvegicus)


name: SOCS-1 and SOCS-3 binds to p-JAK2 (Danio rerio)


name: H(+) + N(3)-methyluridine(2843) in 25S rRNA + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(2843) in 25S rRNA


name: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Canis familiaris)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA <=> (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Mus musculus)


name: thiamine diphosphate(in) => thiamine diphosphate(out)


name: L-serine(in) + Na(+)(in) <=> L-serine(out) + Na(+)(out)


name: all-trans-retinyl hexadecanoate + H2O => H(+) + hexadecanoate + retinol


name: ATP + cob(I)inamide-[corrinoid adenosyltransferase] <=> adenosylcob(III)inamide + apo-[corrinoid adenosyltransferase] + triphosphate


name: 15,17(3)-seco-F430-17(3)-acid + ATP <=> ADP + coenzyme F430 + phosphate


name: LARG activation by G alpha 12/13 (Homo sapiens)


name: LDH tetramer reduces PYR to LACT (Mus musculus)


name: Dimerization of Tie2/Ang1 complex (Mus musculus)


name: an aromatic primary alcohol + O2 <=> an aromatic aldehyde + H2O2


name: CoA + H(+) + N-dodecanoylglycine => dodecanoyl-CoA + glycine


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Schizosaccharomyces pombe)


name: adenosine(1408) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(1408) in 16S rRNA + S-adenosyl-L-homocysteine


name: 3-sulfanylpentan-1-ol-L-cysteine => 2-aminoprop-2-enoate + 3-sulfanyl-1-pentanol


name: RhBG mediates ammonium influx into kidney collecting duct cells (Gallus gallus)


name: Myelin components can interact with p75NTR:NgR:LINGO1 (Homo sapiens)


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Schizosaccharomyces pombe)


name: Transport of L1 into endosomes (Homo sapiens)


name: NADPH + O2 + questin = demethylsulochrin + NADP(+)


name: IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Rattus norvegicus)


name: (R)-2-methyl-3-oxopropanoate + H(+) + NADH => (R)-3-hydroxy-2-methylpropanoate + NAD(+)


name: WWP2 ubiquitinates NOTCH3 (Xenopus tropicalis)


name: ATP + beta-alanine + L-histidine <=> ADP + carnosine + H(+) + phosphate


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] <=> 11alpha-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H2O = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + D-galactose


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate = alpha-himachalene + diphosphate


name: 20-hydroxy-leukotriene B4 + NADP(+) => 12-oxo-20-hydroxy-leukotriene B4 + H(+) + NADPH


name: CYP2U1 19-hydroxylates ARA (Rattus norvegicus)


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] = H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein]


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)


name: NADP(+) + octanal => (2E)-octenal + H(+) + NADPH


name: Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Rattus norvegicus)


name: NADPH + 2 O2 <=> H(+) + NADP(+) + 2 superoxide


name: N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: NQO2:FAD dimer reduces quinones to hydroquinones (Homo sapiens)


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Gallus gallus)


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Homo sapiens)


name: Cholecystokinin receptors bind cholecystokinin (Canis familiaris)


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Mus musculus)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Xenopus tropicalis)


name: a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + diphosphate => a 5'-end diphospho-guanosine in mRNA + GTP + H(+)


name: [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n) + n ATP + n D-aspartate <=> [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + n ADP + n H(+) + n phosphate


name: androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: beta-NGF dimer binds to TrkA receptor (Xenopus tropicalis)


name: (2E)-3-methylhex-2-enoate + L-glutamine => H2O + N(2)-[(2E)-3-methylhex-2-enoyl]-L-glutaminate


name: Formation of pre-mRNPs (Drosophila melanogaster)


name: histone H3R26 methyltransferase activity


name: Latent TGF-beta-3 binds integrins (Xenopus tropicalis)


name: The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)


name: bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+)


name: STAT1 associates with IL6ST:IL6ST (Xenopus tropicalis)


name: WTS binds to SAV (Drosophila melanogaster)


name: gamma-L-glutamyl-hercynylcysteine S-oxide + H2O = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide


name: "gamma-glutamyl hercynylcysteine S-oxide hydrolase"


name: an aldehyde + hydrogen cyanide => a monosubstituted aliphatic (S)-hydroxynitrile


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Mus musculus)


name: 6 AMP + corynebactin + 6 diphosphate + 3 H(+) + 3 H2O => 3 2,3-dihydroxybenzoate + 6 ATP + 3 glycine + 3 L-threonine


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Sus scrofa)


name: an N-(fatty acyl)-glycine + H2O => a fatty acid + glycine


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Rattus norvegicus)


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Rattus norvegicus)


name: A + butanoyl-CoA => (2E)-butenoyl-CoA + AH2


name: (2E)-hexadecenoyl-[ACP] + H(+) + NADPH = hexadecanoyl-[ACP] + NADP(+)


name: glycine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoylglycine


name: benzaldehyde dehydrogenase (NADP+) activity


name: inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Sus scrofa)


name: lactate + H+ [extracellular] <=> lactate + H+ [cytosol] (Gallus gallus)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Plasmodium falciparum)


name: Phosphorylation of PLC-gamma (Homo sapiens)


name: Inactive G alpha (i) reassociates with G beta:gamma (Caenorhabditis elegans)


name: H2O + UDP-N-acetyl-alpha-D-galactosamine = 2 H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UMP


name: ULK1 phosphorylates RIPK1 at S357 (Mus musculus)


name: SUMOylation of TOPORS with SUMO1 (Mus musculus)


name: H2O + O2 + retinal => H(+) + H2O2 + retinoate


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Xenopus tropicalis)


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Rattus norvegicus)


name: 3-phenylpyruvate + L-kynurenine => H2O + kynurenate + L-phenylalanine


name: ADP + dapdiamide B + H(+) + phosphate => ATP + L-isoleucine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate


name: (6R)-5,10-methenyltetrahydrofolate + H2O => (6R)-10-formyltetrahydrofolate + H(+)


name: 3',5'-cyclic GMP(out) => 3',5'-cyclic GMP(in)


name: Homocysteine is degraded to oxobutanoate and H2S (Mus musculus)


name: Activated FMNL3 binds G-actin (Bos taurus)


name: aspartic-type endopeptidase inhibitor activity


name: CoA + H(+) + N-eicosanoyl-sphing-4-enine => eicosanoyl-CoA + sphing-4-enine


name: DIBOA + UDP-alpha-D-glucose <=> DIBOA beta-D-glucoside + H(+) + UDP


name: H2O + L-alanyl-tRNA(Thr) = H(+) + L-alanine + tRNA(Thr)


name: NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Sus scrofa)


name: 1'-hydroxyversicolorone + H(+) + NADPH => (2S)-versicolorone + NADP(+)


name: Phosphorylation of NTAL by p-SYK/Lyn (Homo sapiens)


name: UGT1A10 transfers GlcA from UDP-GlcA to GCTN (Dictyostelium discoideum)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Bos taurus)


name: alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O <=> alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate + H(+)


name: H(+) + kaempferol 7-methyl ether + S-adenosyl-L-homocysteine => kaempferol + S-adenosyl-L-methionine


name: 15-cis-4,4'-diapophytoene + FAD + H(+) <=> all-trans-4,4'-diapophytofluene + FADH2


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-(ribonucleoside) in mRNA + H2O => a 5'-end phospho-ribonucleoside in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: SYS1 binds AcM-ARFRP1 (Drosophila melanogaster)


name: CO binds to free ferrohemoglobin (Gallus gallus)


name: PA is dephosphorylated to DAG by LPIN (Rattus norvegicus)


name: BACH1 is phosphorylated at tyrosine 483 (Homo sapiens)


name: ERK5 translocates to the nucleus (Gallus gallus)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Gallus gallus)


name: H2O + L-asparaginyl-[protein] = L-aspartyl-[protein] + NH4(+)


name: HLCS biotinylates ACACA:Mn2+ (Dictyostelium discoideum)


name: 3'-phosphoadenylyl sulfate + a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) <=> adenosine 3',5'-bisphosphate + beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H(+)


name: 32-oxo-24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase] => 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glycyl-L-leucine(out) + H(+)(out) => glycyl-L-leucine(in) + H(+)(in)


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Canis familiaris)


name: PAN2-PAN3 complex partially deadenylates mRNA (Bos taurus)


name: 4-hydroxy-3-nitrophenylacetaldehyde + H2O2 + NH4(+) => 3-nitrotyramine + H2O + O2


name: N(omega),N(omega)-dimethyl-L-arginine + pyruvate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine


name: type I transforming growth factor beta receptor binding


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Dictyostelium discoideum)


name: RHOD binds effectors at the plasma membrane (Bos taurus)


name: cyathatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cyathadiol + O2 + reduced [NADPH--hemoprotein reductase]


name: H2O2 oxidises ferrohemoglobin to MetHb (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O => 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: 1-dodecanoyl-sn-glycerol 3-phosphate + CoA => dodecanoyl-CoA + sn-glycerol 3-phosphate


name: Haptoglobin:Hemoglobin binds CD163 (Sus scrofa)


name: D-lactate dehydrogenase (quinone) activity


name: p62:MEKK3 binds to TRAF6 (Rattus norvegicus)


name: LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D (Bos taurus)


name: IL21 receptor STAT phosphorylation (Danio rerio)


name: 2 (R)-3-phenyllactate + 2 (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine => 8 AMP + 8 diphosphate + 8 H(+) + PF1022A + 4 S-adenosyl-L-homocysteine


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + pentadecanoyl-CoA <=> (9Z)-pentadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: AH2 + S-(methylsulfanyl)glutathione = A + glutathione + methanethiol


name: NAAA hydrolyses NAEs to FAs and ethanolamine (Caenorhabditis elegans)


name: PIP3 recruits PDPK1 to the membrane (Saccharomyces cerevisiae)


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) => 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADH


name: tBID binds to inactive BAX protein (Mus musculus)


name: Alpha1-Microglobulin binds heme (Gallus gallus)


name: dihydroxyacetone phosphate + formaldehyde => L-erythrulose 1-phosphate


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphate


name: 1-O-(13-methyltetradecyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-O-(1Z-13-methyltetradecenyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Sus scrofa)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Xenopus tropicalis)


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Bos taurus)


name: an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an N-(2R-hydroxyacyl)-4R-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Bos taurus)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA (Dictyostelium discoideum)


name: ADP-riboxanated L-argininyl-[protein] + H(+) + NH4(+) => ADP-1-deoxy-1,O(4)-didehydro-D-ribose + L-arginyl-[protein]


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Mus musculus)


name: argininosuccinate <=> fumarate + arginine (Danio rerio)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Caenorhabditis elegans)


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Schizosaccharomyces pombe)


name: H(+)(out) + xanthosine(out) => H(+)(in) + xanthosine(in)


name: N,N-dimethylaniline N-oxide <=> formaldehyde + N-methylaniline


name: UCHL1, UCHL3 cleave ubiquitin adducts (Dictyostelium discoideum)


name: SRC-1 phosphorylates p-Y397-PTK2 (Mus musculus)


name: SUMOylation of NR1I2 with SUMO3 (Bos taurus)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Mus musculus)


name: PPA2A dephosphorylates SPRY2 (Danio rerio)


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Canis familiaris)


name: (2S)-2-acetolactate + thiamine diphosphate = 2-(1-hydroxyethyl)thiamine diphosphate + pyruvate


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Canis familiaris)


name: NTPDase8 hydrolyzes nucleoside diphosphates (Mus musculus)


name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + phytol = (7Z,10Z,13Z)-hexadecatrienoate phytyl ester + CoA


name: GAB1 phosphorylation by EGFR kinase (Sus scrofa)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Xenopus tropicalis)


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Bos taurus)


name: DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Danio rerio)


name: (9Z,12Z,15Z)-octadecatrienoate + ATP + CoA = (9Z,12Z,15Z)-octadecatrienoyl-CoA + AMP + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base => a 1,2-diacyl-sn-glycerol + an alpha-D-mannosyl-6-(1D-myo-inositol phospho)-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base


name: USP11 deubiquitinates NFKBIA (Homo sapiens)


name: prostaglandin E2(out) => prostaglandin E2(in)


name: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine


name: a 1-acyl-sn-glycero-3-phosphate + a fatty acyl-[ACP] <=> a 1,2-diacyl-sn-glycero-3-phosphate + holo-[ACP]


name: 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA => 7-cyano-7-carbaguanosine(15) in tRNA + L-lysine


name: D-serine(out) + H(+)(out) => D-serine(in) + H(+)(in)


name: ALAD condenses 2 dALAs to form PBG (Mus musculus)


name: TRIM25 binds monoUb:164-PCNA (Bos taurus)


name: WWOX binds TFAP2C (Drosophila melanogaster)


name: NLRX1 inhibits IPS1 signaling (Gallus gallus)


name: D-xylotriose + O2 <=> D-xylotriono-1,5-lactone + H2O2


name: (indol-3-yl)acetate(in) + a dicarboxylate(out) => (indol-3-yl)acetate(out) + a dicarboxylate(in)


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Canis familiaris)


name: a quinone + H2O + L-methionyl-[protein] => a quinol + L-methionyl-(R)-S-oxide-[protein]


name: ATP + O-phospho-L-serine + tRNA(Cys) = AMP + diphosphate + O-phospho-L-seryl-tRNA(Cys)


name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Sus scrofa)


name: Caspase-mediated cleavage of Lamin B1 (Mus musculus)


name: AKR1B1 reduces Glc to D-sorbitol (Bos taurus)


name: Oxoeicosanoid receptor can bind oxoeicosanoid (Homo sapiens)


name: p190RhoGAP binds Plexin-B1 (Homo sapiens)


name: NR3C2 binds NR3C2 antagonists (Homo sapiens)


name: a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1aalpha (d18:1(4E)) + CMP + H(+)


name: TDP1 and TDP2 process unligatable DSB ends (Canis familiaris)


name: H(+) + NADPH + O2 + tryprostatin B <=> demethoxyfumitremorgin C + 2 H2O + NADP(+)


name: ABCG4 may mediate cholesterol efflux (Drosophila melanogaster)


name: CBP and p300 binds NF-kB complex (Mus musculus)


name: Autocatalytic activation of bound proMMP2 (Rattus norvegicus)


name: 5alpha,6beta,17alpha,27-tetrahydroxywithanolide + UDP-alpha-D-glucose = 5alpha,6beta,17alpha-trihydroxywithanolide 27-O-beta-D-glucoside + H(+) + UDP


name: oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin] => hnu + oxidized [2Fe-2S]-[ferredoxin] + reduced [plastocyanin]


name: crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) (Rattus norvegicus)


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Rattus norvegicus)


name: L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine


name: PTPN3 binds p-T183,Y185 MAPK12 (Caenorhabditis elegans)


name: 5''-phosphoribostamycin + H2O <=> phosphate + ribostamycin


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: GLUT1 tetramer binds 4xATP (Danio rerio)


name: Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Mus musculus)


name: aklavinone + dTDP-beta-L-rhodosamine = aclacinomycin T + dTDP + 2 H(+)


name: Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure (Xenopus tropicalis)


name: KDM5A-D demethylate Me3K5-histone H3 (Sus scrofa)


name: TRAPPC complexes exchange GTP for GDP on RAB1 (Bos taurus)


name: Formation of hydroxylysyl-pyrrole cross-links (Sus scrofa)


name: H2O + hypoxanthine + NAD(+) => H(+) + NADH + xanthine


name: ATP + carbamoyl phosphate + H2O + kanamycin A = 6''-O-carbamoylkanamycin A + AMP + diphosphate + H(+) + phosphate


name: 2 H(+)(out) + L-aspartate(out) => 2 H(+)(in) + L-aspartate(in)


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Sus scrofa)


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Caenorhabditis elegans)


name: PEX19 binds class I peroxisomal membrane proteins (Canis familiaris)


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Rattus norvegicus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + L-serine


name: ADP + alpha-maltose 1-phosphate + H(+) => ADP-alpha-D-glucose + alpha-D-glucose 1-phosphate


name: Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)


name: The COG complex binds RABs at the Golgi membrane (Canis familiaris)


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Caenorhabditis elegans)


name: H2O + lanosteryl ester = a carboxylate + H(+) + lanosterol


name: H(+) + N-tetracosanoyl-(4R)-hydroxysphinganine + NADPH + O2 => H2O + N-(2-hydroxytetracosanoyl)-(4R)-hydroxysphinganine + NADP(+)


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Bos taurus)


name: a D-alpha-amino acid + a quinone + H2O = a 2-oxocarboxylate + a quinol + NH4(+)


name: SGMS1 transfers phosphocholine onto ceramide (Caenorhabditis elegans)


name: ERBB3 binds RNF41 ubiquitin ligase (Bos taurus)


name: p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Xenopus tropicalis)


name: (2E)-geranyl diphosphate => (1R,5R)-alpha-pinene + diphosphate


name: STAB1:ligand is endocytosed (Gallus gallus)


name: L-methionine(in) + L-phenylalanine(out) <=> L-methionine(out) + L-phenylalanine(in)


name: (E)-sinapoyl-CoA + D-glucono-1,5-lactone = 6-O-[(E)-sinapoyl]-D-glucono-1,5-lactone + CoA


name: a 1-acylglycerone 3-phosphate + H(+) + NADPH <=> a 1-acyl-sn-glycero-3-phosphate + NADP(+)


name: Activated NTRK2 binds FRS3 (Homo sapiens)


name: adenosylcobinamide kinase (ATP-specific) activity


name: (9Z)-hexadecenoyl-CoA + 1,2-dihexadecanoyl-sn-glycerol => 1,2-dihexadecanoyl-3-(9Z-hexadecenoyl)-sn-glycerol + CoA


name: CHOL translocates from lysosome membrane to ER membrane (Sus scrofa)


name: N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine <=> (9Z,12Z,15Z)-octadecatrienamide + glyoxylate


name: Recruitment of CDK11p58 to the centrosomes (Rattus norvegicus)


name: dimethyl sulfoxide + H2O + NAD(+) <=> dimethyl sulfone + H(+) + NADH


name: Interleukin-5 is a homodimer (Homo sapiens)


name: cytidine(1409) in 16S rRNA + S-adenosyl-L-methionine => 2'-O-methylcytidine(1409) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: methanesulfonate + NADH + O2 = formaldehyde + H2O + NAD(+) + sulfite


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)


name: Edited Kainate Receptor binds glutamate (Canis familiaris)


name: (R)-glycerate + ADP-alpha-D-glucose => (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+)


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Caenorhabditis elegans)


name: 2-oxoglutarate + FADH2 => (S)-2-hydroxyglutarate + FAD + H(+)


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Homo sapiens)


name: Aquaporin-1 passively transports water out of cell (Canis familiaris)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Dictyostelium discoideum)


name: 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+) => 1-hexanoyl-sn-glycero-3-phosphocholine + H2O


name: SFTPD binds with itself to form SFTPD 12mer (Danio rerio)


name: OTUD3 deubiquitinates PTEN (Mus musculus)


name: Adenylate cyclase converts ATP into cyclic AMP (Gallus gallus)


name: 6beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + testosterone


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(38-hydroxyoctatriacontenoyl)-sphing-4-enine => a diacylglycerol + an N-(38-(9Z,12Z-octadecadienoyloxy)-octatriacontenoyl)-sphing-4-enine


name: n a ribonucleoside 5'-phosphate + n H(+) => (n-1) H2O + RNA(n)


name: (3Z)-phycoerythrobilin + oxidized 2[4Fe-4S]-[ferredoxin] = 15,16-dihydrobiliverdin + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: SETD9 methylates TP53 (Canis familiaris)


name: abacavir [extracellular] => abacavir [cytosol] (Sus scrofa)


name: STEAP3-like proteins reduce Fe3+ to Fe2+ (Rattus norvegicus)


name: ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG (Xenopus tropicalis)


name: PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body (Canis familiaris)


name: Expression of ZEB2 in neural plate (Homo sapiens)


name: a 1-acylglycerol + hexadecanoyl-CoA = an hexadecanoyl-acylglycerol + CoA


name: alfacalcidol + O2 + reduced [NADPH--hemoprotein reductase] = calcitriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-apionolactone + H(+) + NADH => D-apiofuranose + NAD(+)


name: (1S,2S,4R)-beta-elemene + diphosphate => (2E,6E)-farnesyl diphosphate


name: apo-[corrinoid adenosyltransferase] + cob(II)inamide <=> cob(II)inamide-[corrinoid adenosyltransferase]


name: ATP + holo-[ACP] + tetradecanoate <=> AMP + diphosphate + tetradecanoyl-[ACP]


name: a 1-acyl-sn-glycero-3-phosphate + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: D-serine(out) + H(+)(out) = D-serine(in) + H(+)(in)


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Gallus gallus)


name: a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose => 1,2-diacyl-3-O-[alpha-D-glucosyl-(1-> 2)-alpha-D-glucosyl]-sn-glycerol + H(+) + UDP


name: Nuclear TIM is degraded by the 26S proteasome (Drosophila melanogaster)


name: O2 + pre-flavunoidine + reduced [NADPH--hemoprotein reductase] => 10-hydroxy-pre-flavunoidine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: USP13 and OTUD3 deubiquitinate PTEN (Xenopus tropicalis)


name: 1-hydroxy-5alpha-androstan-3,17-dione + A <=> 5alpha-androstan-1,3,17-trione + AH2


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Mus musculus)


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Rattus norvegicus)


name: epiandrosterone 3-sulfate(out) + 2 Na(+)(out) = epiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Danio rerio)


name: Phosphorylated STATs are released (Rattus norvegicus)


name: a flavonol + UDP-alpha-D-glucose = a flavonol 3-O-beta-D-glucoside + H(+) + UDP


name: D-xylotetraono-1,5-lactone + H2O => D-xylotetraonate + H(+)


name: ATM phosphorylates WHSC1 (Dictyostelium discoideum)


name: H2O + L-lysyl-[protein] + O2 <=> (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+)


name: Thrombin binding to GP1b:IX:V (Xenopus tropicalis)


name: H2O2 + precondylocarpine acetate => O-acetyl-15alpha-stemmadenine + O2


name: D-erythrulose 1-phosphate => L-erythrulose 1-phosphate


name: SGMS2 transfers phosphocholine onto ceramide (Canis familiaris)


name: a ganglioside GA1 + N-acetylneuraminate => a ganglioside GM1 + H2O


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Bos taurus)


name: 2-amino-4-hydroxypteridine + O2 <=> 2-amino-4,7-dihydroxypteridine + chemical entity


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Homo sapiens)


name: SARS-CoV-2 N binds to G3BP1,G3BP2 (Homo sapiens)


name: Abortive initiation after formation of the first phosphodiester bond (Dictyostelium discoideum)


name: H2O + N-(2-phenylethyl)acetamide <=> 2-phenylethylamine + acetate


name: 2 H(+)(out) + L-aspartyl-glycine(out) <=> 2 H(+)(in) + L-aspartyl-glycine(in)


name: p75NTR interacts with RIP2 (Xenopus tropicalis)


name: 2-dehydro-D-glucose = cortalcerone + H2O


name: CTSL bind CTSL inhibitors (Homo sapiens)


name: erinacol + O2 + reduced [NADPH--hemoprotein reductase] = cyathadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ZnT5 transports zinc into the golgi apparatus (Xenopus tropicalis)


name: Asc.- radical dissociates to AscH- and DeHA (Homo sapiens)


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Homo sapiens)


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O => a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+)


name: pseudouridine(2457) in 23S rRNA => uridine(2457) in 23S rRNA


name: (1S,2S)-1,2-dihydronaphthalene-1,2-diol + NADP(+) <=> H(+) + NADPH + naphthalene-1,2-diol


name: LAIR1 binds collagen (Rattus norvegicus)


name: HS-GAGs translocate to the lysosome for degradation (Homo sapiens)


name: H2O + N(2)-(4-aminobutanoyl)-L-lysine => 4-aminobutanoate + L-lysine


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Mus musculus)


name: PGH2 is isomerised to PGE2 by PTGES (Drosophila melanogaster)


name: hexadecan-1-ol + holo-[ACP] + 2 NADP(+) => 2 H(+) + hexadecanoyl-[ACP] + 2 NADPH


name: S-ethyl-L-cysteine <=> 2-aminoprop-2-enoate + ethanethiol


name: a primary alcohol + 2 Fe(III)-[cytochrome c] <=> an aldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: 4alpha-methylzymosterol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 = 4alpha-carboxyzymosterol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: ATP + beta-D-fructose 1-phosphate <=> ADP + beta-D-fructose 1,6-bisphosphate + H(+)


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Saccharomyces cerevisiae)


name: (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein] => (7Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Schizosaccharomyces pombe)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)


name: PA is converted to CDP-DAG by CDS2 (Caenorhabditis elegans)


name: (Z)-glucotropeolin + H2O <=> (Z)-phenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: (3S)-3-aminobutanoyl-CoA + acetoacetate => (5S)-5-amino-3-oxohexanoate + acetyl-CoA


name: a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+) => a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate


name: (R)-reticuline + S-adenosyl-L-methionine => (R)-laudanine + H(+) + S-adenosyl-L-homocysteine


name: TRAF6 binds to p75NTR:NRIF (Rattus norvegicus)


name: 5-dehydro-6-demethoxy-6-hydroxyfumagillol + S-adenosyl-L-methionine = 5-dehydrofumagillol + H(+) + S-adenosyl-L-homocysteine


name: p-4Y-SIRPA:CD47 binds GRB2-1 (Homo sapiens)


name: (E)-ferulate + ATP + CoA <=> (E)-feruloyl-CoA + AMP + diphosphate


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Xenopus tropicalis)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + tetradecanoyl-[ACP] = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + holo-[ACP]


name: 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] <=> 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTP1B dephosphorylates GHR (Rattus norvegicus)


name: 2 H(+) + m-xylene + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3-methylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 FAD + 6 H2O => (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 bromide + 3 FADH2 + 3 O2


name: FOXP3 in complex with RUNX1 binds to the TNFRSF18 (GITR) gene intron 1 (Homo sapiens)


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Bos taurus)


name: TBC1D20 binds RAB1:GTP (Saccharomyces cerevisiae)


name: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H(+) + O2 => aureusidin 6-O-beta-glucoside + H2O


name: Binding of APOBEC-1 to form editosome (Mus musculus)


name: (4R)-hydroxysphinganine + tetracosanoate => H2O + N-tetracosanoyl-(4R)-hydroxysphinganine


name: ABC7, mABC1 and mABC2 mediate heme transport (Rattus norvegicus)


name: CLN3 transports GalCer to plasma membrane (Saccharomyces cerevisiae)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Drosophila melanogaster)


name: 6-deoxyerythronolide B + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> erythronolide B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (6E)-8-methylnon-6-enoyl-CoA + 4-hydroxy-3-methoxy-benzenemethanol <=> capsiate + CoA


name: (S)-3'-hydroxy-N-methylcoclaurine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-N-methylcoclaurine + O2 + reduced [NADPH--hemoprotein reductase]


name: (3Z)-hex-3-en-1-ol + benzoyl-CoA = (3Z)-hex-3-en-1-yl benzoate + CoA


name: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde


name: a cytidine in rRNA + S-adenosyl-L-methionine => a 5-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: SEPHS2 phosphorylates H2Se to form SELP (Canis familiaris)


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 = 1-O-methyl-(9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: RHOC binds effectors at the plasma membrane (Schizosaccharomyces pombe)


name: chloride + FADH2 + L-tryptophan + O2 <=> 6-chloro-L-tryptophan + FAD + 2 H2O


name: (2E,6E)-farnesyl diphosphate => beta-copaene + diphosphate


name: MASTL (GWL) phosphorylates ARPP19 (Danio rerio)


name: Dynamin is recruited to the gap junction plaque (Sus scrofa)


name: SLC4A4 cotransports Na+ with 3HCO3- (Drosophila melanogaster)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Gallus gallus)


name: Unwinding DNA for the nascent transcript (Caenorhabditis elegans)


name: PKC phosphorylates GRK2 (Caenorhabditis elegans)


name: CREB3L3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Canis familiaris)


name: CASP9 is phosphorylated at T412 (Drosophila melanogaster)


name: An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Bos taurus)


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Bos taurus)


name: USP28 deubiquitinates CLSPN and MYC (Sus scrofa)


name: a diacylglycerol + N-(32-(9Z,12Z-octadecadienoyloxy)-dotricontanoyl)-sphing-4-enine => a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(32-hydroxydotriacontanoyl)-sphing-4-enine


name: dopamine + secologanin => deacetylisoipecoside + H2O


name: demethyllactenocin + dTDP + H(+) => 5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose


name: PALM-C100-CKAP4 binds SFTPAs (Rattus norvegicus)


name: L-alanine(in) + Na(+)(in) => L-alanine(out) + Na(+)(out)


name: EP2 and EP4 receptors can bind PGE2 (Drosophila melanogaster)


name: SCF-FBXL7 ubiquitinates AURKA (Homo sapiens)


name: PP2A dephosphorylates KSR1 (Rattus norvegicus)


name: L-cysteinyl-[protein] + methylglyoxal => S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein]


name: H2O + L-methionyl-(R)-S-oxide-[F-actin] + NADP(+) => H(+) + L-methionyl-[F-actin] + NADPH + O2


name: CoA + NAD(+) + phenylglyoxylate => benzoyl-CoA + CO2 + NADH


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Bos taurus)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Schizosaccharomyces pombe)


name: (indol-3-yl)acetate + H(+) + NADH + O2 <=> 2-hydroxy-(1H-indol-3-yl)acetate + H2O + NAD(+)


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Xenopus tropicalis)


name: myricetin 3-O-alpha-L-rhamnoside + UDP-alpha-D-glucose = H(+) + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + UDP


name: DOLPP1 dephosphorylates DOLDP to DOLP (Schizosaccharomyces pombe)


name: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil


name: 5-hydroxythiophene-2-carbonyl-CoA + A + H(+) + H2O => AH2 + O2 + thiophene-2-carbonyl-CoA


name: H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + solavetivone => O2 + reduced [NADPH--hemoprotein reductase] + solavetivol


name: (1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H(+) + H2O


name: (3R)-hydroxydodecanoyl-[ACP] = (2E)-dodecenoyl-[ACP] + H2O


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Homo sapiens)


name: H2O + streptothricin D <=> streptothricin D acid


name: a 2,3-diacyl-sn-glycerol + H2O => a 3-acyl-sn-glycerol + a fatty acid + H(+)


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Sus scrofa)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)


name: ABCB1 transports xenobiotics out of the cell (Sus scrofa)


name: H2O + sn-glycero-3-phospho-L-serine = H(+) + L-serine + sn-glycerol 3-phosphate


name: (6R)-5,10-methenyltetrahydrofolate + H2O = (6S)-5-formyl-5,6,7,8-tetrahydrofolate + H(+)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Sus scrofa)


name: (3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA + NAD(+) = (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H(+) + NADH


name: L-lysine(in) + L-ornithine(out) <=> L-lysine(out) + L-ornithine(in)


name: OPTN binds polyUb-RIPK1 within the TNFR1 complex (Homo sapiens)


name: PRC2 trimethylates histone H3 at lysine-27 (Homo sapiens)


name: SUMOylation of DDX5 with SUMO1 (Caenorhabditis elegans)


name: IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Sus scrofa)


name: PRC1 SUMOylates CTBP1 with SUMO2,3 (Gallus gallus)


name: SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Sus scrofa)


name: Cleavage of mRNA at the 3'-end (Sus scrofa)


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Caenorhabditis elegans)


name: FMO3:FAD N-oxidises TMA to TMAO (Mus musculus)


name: Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase (Homo sapiens)


name: RAC2 binds effectors at the mitochondrial outer membrane (Xenopus tropicalis)


name: ATP + H2O + xanthine(out) <=> ADP + H(+) + phosphate + xanthine(in)


name: AGT(34-41) binds to AGTR2 (Drosophila melanogaster)


name: 2 Fe(II)-[cytochrome c] + H(+) + nitroxyl + O2 <=> 2 Fe(III)-[cytochrome c] + H2O + nitrite


name: 2 ATP => adenosine 3'-diphosphate,5'-triphosphate + AMP


name: glycylglycyl-L-proline(in) + H(+)(in) => glycylglycyl-L-proline(out) + H(+)(out)


name: botD HC:LC binds SV2A or B or C and GD2 on the target cell surface (Homo sapiens)


name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine (Homo sapiens)


name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Canis familiaris)


name: PP2A demethylation by PPME1 (Schizosaccharomyces pombe)


name: (R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+)


name: L-leucine(in) + L-ornithine(out) + Na(+)(in) => L-leucine(out) + L-ornithine(in) + Na(+)(out)


name: 2-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + glycerol + H(+)


name: a ganglioside GM1 (d18:1(4E)) + H2O <=> a ganglioside GM2 (d18:1(4E)) + D-galactose


name: a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA


name: epitestosterone + H(+) + NADPH <=> 5beta-dihydroepitestosterone + NADP(+)


name: dCMP + H2O => dUMP + NH4+ (Homo sapiens)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Saccharomyces cerevisiae)


name: 2 H(+) + hexadecanoyl-[ACP] + 2 NADPH = hexadecan-1-ol + holo-[ACP] + 2 NADP(+)


name: 2,6-dihydroxypseudooxynicotine + H2O <=> 2,6-dihydroxypyridine + 4-(methylamino)butanoate + H(+)


name: Endonucleolytic RISC hydrolyzes target RNAs (Sus scrofa)


name: ADP + H(+) + nitrate(in) + phosphate => ATP + H2O + nitrate(out)


name: AVP:AVPR2 Complex binds inactive heterotrimeric G(s) complex (Homo sapiens)


name: Dissociation of PERK:BiP Heterodimer (Homo sapiens)


name: butan-2-one + NADP(+) = but-3-en-2-one + H(+) + NADPH


name: 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H(+) => 3',3'-c-di-AMP + H2O


name: mTORC1 phosphorylates AKT1S1 (Homo sapiens)


name: ATP + L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) <=> ADP + H(+) + L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: VLDL binds APOC1 and APOC4 (Canis familiaris)


name: SFTPA genes produce SFTPA proteins (Homo sapiens)


name: an N-alkylglycine + H2O + O2 => an alkylamine + glyoxylate + H2O2


name: choline(out) + 2 H(+)(in) => choline(in) + 2 H(+)(out)


name: SUMOylation of RXRA with SUMO1 (Mus musculus)


name: AMP + CoA + diphosphate + 2 H(+) + tenuazonic acid => acetoacetyl-CoA + ATP + L-isoleucine


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Xenopus tropicalis)


name: ORC6 is phosphorylated on T195 (Mus musculus)


name: H(+) + NADPH + O2 + sulcatone = 4-methylpent-3-en-1-yl acetate + H2O + NADP(+)


name: H2O + L-isoleucine + O2 => (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: dihydroprecondylocarpine acetate => acetate + catharanthine + H(+)


name: ATP + ethanolamine <=> ADP + H(+) + phosphoethanolamine


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Dictyostelium discoideum)


name: 13-cis-retinol + hexadecanoyl-CoA <=> 13-cis-retinyl hexadecanoate + CoA


name: 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose <=> (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + H(+) + UDP


name: calcidiol + UDP-alpha-D-glucuronate <=> calcidiol 25-O-(beta-D-glucuronide) + H(+) + UDP


name: SMURF2 ubiquitinates SMAD2 (Mus musculus)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Bos taurus)


name: Caspase-mediated cleavage of FADK 1 (Gallus gallus)


name: ATP + D-arabinose <=> ADP + D-arabinose 5-phosphate + H(+)


name: RNF8 and RNF168 ubiquitinate H2AFX (Gallus gallus)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Danio rerio)


name: WWTR1 (TAZ), TBX5, and PCAF form a complex (Sus scrofa)


name: Sulfite is oxidized to sulfate (Xenopus tropicalis)


name: DAG is acylated to TAG by DGAT1/2 (Rattus norvegicus)


name: acetoin + CoA + NAD(+) = acetaldehyde + acetyl-CoA + H(+) + NADH


name: an acylcholine + H2O => a carboxylate + choline + H(+)


name: a fatty acid + ATP <=> a fatty acyl monophosphate + ADP


name: 5-hydroxyuridine(34) in tRNA + S-adenosyl-L-methionine => 5-methoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: ZIP6 and ZIP14 mediate zinc influx into cells (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycerol + Ins-1-P-Cer(d18:0/2-OH-26:0) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxyhexacosanoyl)-sphinganine


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: H(+) + NADPH + O2 + versicolorin B <=> 2 H2O + NADP(+) + versicolorin A


name: ATP(in) + CoA(in) + H(+)(out) + hexadecanoate(out) = AMP(in) + diphosphate(in) + H(+)(in) + hexadecanoyl-CoA(in)


name: 2 2',3,4-trihydroxy-trans-chalcone + 2 H(+) + O2 => 2 3',4'-dihydroxyaurone + 2 H2O


name: Interleukin-16 is secreted (Rattus norvegicus)


name: Active PLCG1 dissociates from TrkA receptor (Homo sapiens)


name: AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl) => ATP + L-pyrrolysine + tRNA(Pyl)


name: MADD exchanges GTP for GDP on RAB27 (Rattus norvegicus)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Canis familiaris)


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Mus musculus)


name: a secondary alkyl amine + H2O + NAD(+) = a ketone + H(+) + NADH + NH4(+)


name: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)


name: eicosanoate + glycine <=> H2O + N-eicosanoylglycinate


name: H2O + N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine => L-asparagine + N-acetyl-D-glucosamine


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 17-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Trimerization of TRAIL:TRAIL receptor complex (Rattus norvegicus)


name: Formation of lysyl-pyrrole cross-links (Homo sapiens)


name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 (Danio rerio)


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Drosophila melanogaster)


name: HMG CoA => acetoacetic acid + acetyl CoA (Drosophila melanogaster)


name: SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Xenopus tropicalis)


name: NAD+- protein-lysine ADP-ribosyltransferase activity


name: L-lysyl-[protein] + NAD(+) = H(+) + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] + nicotinamide


name: STAT1,STAT3,STAT6 phosphorylation (Rattus norvegicus)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Homo sapiens)


name: a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine <=> a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]


name: The anterograde IFT train dissociates (Rattus norvegicus)


name: PAAP-A proteolyzes IGF:IGFBP4 (Gallus gallus)


name: H2O2 + tetradecanoate = (2S)-hydroxytetradecanoate + H2O


name: hydrolase activity, hydrolyzing N-glycosyl compounds


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + H(+) + phosphate


name: 2-hydroxy-5-methylquinone + H(+) + H2O + NADP(+) + nitrite => 4-methyl-5-nitrocatechol + NADPH + O2


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Sus scrofa)


name: A + dihydroserpentine <=> AH2 + serpentine


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide


name: ACLY tetramer transforms CIT to Ac-CoA (Drosophila melanogaster)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Sus scrofa)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Saccharomyces cerevisiae)


name: Collagen type XIX degradation (Drosophila melanogaster)


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Sus scrofa)


name: glyoxylate + H(+) + NADH => glycolate + NAD(+)


name: Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Homo sapiens)


name: ATP + CoA + docosanoate = AMP + diphosphate + docosanoyl-CoA


name: Association of procollagen type XIV (Gallus gallus)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Homo sapiens)


name: IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Homo sapiens)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Sus scrofa)


name: p-STAT3 dissociates from IL24:IL22RA1:p‑JAK1:IL20RB:p‑STAT3 (Sus scrofa)


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Sus scrofa)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst) (Sus scrofa)


name: a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Saccharomyces cerevisiae)


name: ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB (Sus scrofa)


name: H(+) + H2O + L-dopa + O2 => 3,4-dihydroxyphenylacetaldehyde + CO2 + H2O2 + NH4(+)


name: a wax ester + H2O <=> a long chain fatty alcohol + a long-chain fatty acid + H(+)


name: a dolichyl beta-D-glucosyl phosphate + H2O <=> a dolichyl phosphate + D-glucose + H(+)


name: 5-dehydro-4-deoxy-D-glucarate <=> 2-hydroxy-3-oxopropanoate + pyruvate


name: H2O + O2 + pyridoxamine <=> H2O2 + NH4(+) + pyridoxal


name: Activation of ISG15 by UBA7 E1 ligase (Dictyostelium discoideum)


name: GPVI binds Fyn and Lyn (Canis familiaris)


name: PRKD1,2,3 phosphorylates CERT1-2 (Drosophila melanogaster)


name: 5alpha-pregnane-3,20-dione + NADP(+) <=> H(+) + NADPH + progesterone


name: PIP3 binds to RhoA and activates it (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate => beta-phellandrene + diphosphate


name: glucosamine 6-phosphate N-acetyltransferase activity


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Drosophila melanogaster)


name: TLR folding by chaperones GP96 and CNPY3 (Sus scrofa)


name: GPCR neuropeptide receptor binds neuropeptides B and W (Homo sapiens)


name: RUNX3 binds EP300 (Caenorhabditis elegans)


name: 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O = 4-oxohex-2-enedioate + H(+)


name: malonate-semialdehyde dehydrogenase (acetylating) activity


name: BRISC complex deubiquitinates NLRP3 (Mus musculus)


name: diphosphate + hydropyrenol => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Bos taurus)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Mus musculus)


name: Collagen type XIV degradation by MMP9,13 (Homo sapiens)


name: Nucleoprotein is ADP-ribosylated (Homo sapiens)


name: TRAF1 binds TRAF2 within TNFR1 signaling complex (Rattus norvegicus)


name: PHGDH tetramer dehydrogenates 3PG (Rattus norvegicus)


name: GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H(+)


name: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO2


name: 3 menaquinone-8 + protoporphyrinogen IX <=> 3 menaquinol-8 + protoporphyrin IX


name: 16alpha-hydroxyestrone 16-O-(beta-D-glucuronate) + H(+) + UDP => 16alpha-hydroxyestrone + UDP-alpha-D-glucuronate


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-glycine


name: RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity


name: (13E)-labda-7,13-dien-15-yl diphosphate => diphosphate + labda-7,13(16),14-triene


name: 1-methyladenosine + H2O <=> 1-methyladenine + D-ribose


name: 5-phosphomethyl-dUMP in DNA + ADP + H(+) => 5-hydroxymethyl-dUMP in DNA + ATP


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Homo sapiens)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Homo sapiens)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tyrosine => 3-(4-hydroxyphenyl)pyruvate + L-kynurenine


name: DOLK phosphorylates DCHOL to DOLP (Homo sapiens)


name: ATP + H2O + Mn(2+)(in) = ADP + H(+) + Mn(2+)(out) + phosphate


name: (2Z,6E)-farnesyl diphosphate + 9 isopentenyl diphosphate => di-trans,nona-cis-dodecaprenyl diphosphate + 9 diphosphate


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Gallus gallus)


name: Nuclear VBC complex ubiquitinylates HIF-alpha (Rattus norvegicus)


name: I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol (Sus scrofa)


name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Bos taurus)


name: GPR161 is internalized (Rattus norvegicus)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + 2 H2O = 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + 2 chloride + 2 H(+)


name: NT5C2 tetramer dephosphorylates RBV-MP (Xenopus tropicalis)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Dictyostelium discoideum)


name: SUMOylation of MDC1 with SUMO2,3 (Drosophila melanogaster)


name: ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Mus musculus)


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Caenorhabditis elegans)


name: (3R)-hydroxy-(9Z)-hexadecenoyl-[ACP] + NADP(+) => 3-oxo-(9Z)-hexadecenoyl-[ACP] + H(+) + NADPH


name: (2E)-butenoyl-[ACP] + H2O => (3R)-hydroxybutanoyl-[ACP]


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)


name: CARM1 methylates arginine-18 (H3R17) of histone H3 (Mus musculus)


name: (R)-demethyl-4-deoxygadusol + H(+) + H2O + phosphate => D-sedoheptulose 7-phosphate


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate


name: PKC-delta translocates to plasma membrane (Saccharomyces cerevisiae)


name: (25S)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Expression of peptide bound class I MHC on cell surface (Danio rerio)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Sus scrofa)


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Canis familiaris)


name: NMT1/2 transfer MYS to GNAT1 (Danio rerio)


name: 3',5'-cyclic AMP(out) + a dicarboxylate(in) = 3',5'-cyclic AMP(in) + a dicarboxylate(out)


name: p-PKR dimer phosphorylates CDK1 (Sus scrofa)


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Drosophila melanogaster)


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)


name: docosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-docosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: adenosine 3',5'-bisphosphate + cholate 7-sulfate + H(+) => 3'-phosphoadenylyl sulfate + cholate


name: (R)-10-hydroxyoctadecanoate => (9Z)-octadecenoate + H2O


name: (2S)-3-sulfopropanediol + NAD(+) <=> (2S)-3-sulfolactaldehyde + H(+) + NADH


name: isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity


name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH


name: 1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in) => 1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Drosophila melanogaster)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Xenopus tropicalis)


name: 6-deoxoteasterone + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydro-6-deoxoteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-carboxy-L-lyxonate + H(+) <=> CO2 + L-lyxonate


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Gallus gallus)


name: CHOL translocates from cytosol to mitochondrial intermembrane space (Homo sapiens)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Homo sapiens)


name: (2S)-2-aminobutanoate + 2-oxo-3-sulfanylpropanoate => 2-oxobutanoate + L-cysteine


name: Transfer of ubiquitin from E1 to E2 (Sus scrofa)


name: Recruitment of POLB to the AP site (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate <=> (1R,4R,5S)-acoradiene + diphosphate


name: D-glucose 6-sulfate + H2O <=> D-glucose + H(+) + sulfate


name: D-glucose + O-sinapoylcholine => 1-O-(trans-sinapoyl)-beta-D-glucose + choline


name: Vitronectin (VTN) binds to C5b:C6:C7 (Homo sapiens)


name: DHODH:FMN oxidises (S)-DHO to orotate (Mus musculus)


name: chloroacetaldehyde + H2O + NADP(+) <=> chloroacetate + 2 H(+) + NADPH


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => diphosphate + hydropyrenol


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Rattus norvegicus)


name: UROD decarboxylates URO3 to COPRO3 (Schizosaccharomyces pombe)


name: H(+)(in) + L-histidine(out) + Na(+)(out) <=> H(+)(out) + L-histidine(in) + Na(+)(in)


name: Reduction of disulphide bonds in MHC II antigens (Bos taurus)


name: hexadecanoyl-CoA + sphinga-(4E,8E)-dienine <=> CoA + H(+) + N-hexadecanoylsphinga-(4E,8E)-dienine


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Caenorhabditis elegans)


name: IL22 binds IL22RA1:JAK1 receptor complex (Homo sapiens)


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Homo sapiens)


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-ribose 1-phosphate <=> (2R)-3-phosphoglycerate + alpha-D-ribose 1,5-bisphosphate + H(+)


name: 6-phospho-D-gluconate + NADP(+) => 6-phospho-2-dehydro-D-gluconate + H(+) + NADPH


name: H(+) + hexadecanoate + NADPH + O2 = 15-hydroxyhexadecanoate + H2O + NADP(+)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Drosophila melanogaster)


name: Association of procollagen type XVII (Sus scrofa)


name: 3alpha(S)-strictosidine + H2O => D-glucose + strictosidine aglycone


name: ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine <=> (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine


name: ATP + gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate = ADP + H(+) + L-glutamyl-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + phosphate


name: IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Homo sapiens)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Bos taurus)


name: Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Rattus norvegicus)


name: a 14alpha-methyl steroid + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] = a Delta(14) steroid + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: (2E)-geranyl diphosphate + L-tryptophyl-[protein] => (2S,3R)-3-geranyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate


name: SLITs bind keratan sulfate (Canis familiaris)


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Rattus norvegicus)


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Sus scrofa)


name: LIPH, I hydrolyse PA to 2-acyl LPA (Xenopus tropicalis)


name: calycosin + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + pseudobaptigenin


name: dimethylamine + H(+) + H2O + oxidized [electron-transfer flavoprotein] = formaldehyde + methylamine + reduced [electron-transfer flavoprotein]


name: 4-hydroxyestrone + NH4(+) + O2 => 2 H(+) + 2 H2O + pyridinestrone carboxylate


name: TANK binds polyubiquitinated TRAF3/6 (Gallus gallus)


name: JAK2 Phosphorylates STAT5 in Response to Leptin (Homo sapiens)


name: mitochondrial transcription factor activity


name: H(+) + NADPH + selenodiglutathione = glutathione + glutathioselenol + NADP(+)


name: H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] => L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate


name: p38MAPK phosphorylates MSK1 (Canis familiaris)


name: (2R,5R)-isomenthone + NADP(+) => (R)-pulegone + H(+) + NADPH


name: butyl 2-(methylsulfanyl)acetate + CoA => 2-(methylsulfanyl)acetyl-CoA + butan-1-ol


name: an acyl phosphate + holo-[ACP] => a fatty acyl-[ACP] + phosphate


name: Rifampicin binds Mtb RNAP (Homo sapiens)


name: CTNNB1 T41 mutants aren't phosphorylated by GSK3beta (Homo sapiens)


name: Activation of Rac1 by pVav1 (Homo sapiens)


name: TPMT transfers CH3 from AdoMet to 6MP (Mus musculus)


name: 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + UDP => di-trans,octa-cis-undecaprenyl phosphate + UDP-4-deoxy-4-formamido-beta-L-arabinose


name: ARV1 transports CHOL from ER membrane to plasma membrane (Drosophila melanogaster)


name: G-protein subunits dissociate from WNT:FZD complex (Caenorhabditis elegans)


name: L-leucine(out) + L-methionine(in) = L-leucine(in) + L-methionine(out)


name: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde


name: Dentin phosphoprotein binds integrin alphaVbeta1 (Canis familiaris)


name: Transfer of ISG15 from E1 to E2 (UBCH8) (Homo sapiens)


name: Bitter compound binds bitter taste receptor (TAS2R) (Gallus gallus)


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Bos taurus)


name: A + ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] = AH2 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + serpentine


name: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively (Xenopus tropicalis)


name: 4-nitrophenyl sulfate + adenosine 3',5'-bisphosphate => 3'-phosphoadenylyl sulfate + 4-nitrophenol


name: Activated FGFR3 binds FRS2 (Canis familiaris)


name: 1-O-methyl-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate => 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Dictyostelium discoideum)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + CoA => hexadecanoyl-CoA + sn-glycerol 3-phosphate


name: (2S-3S)-versiconal hemiacetal + H(+) + NADPH => (S)-versiconol + NADP(+)


name: H2O + pheophorbide a = C-13(2)-carboxypyropheophorbide a + methanol


name: Association of Rb with Cyclin E:Cdk2 complexes (Xenopus tropicalis)


name: MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB (Mus musculus)


name: P4HB binds Collagen chains (Xenopus tropicalis)


name: Interaction of DAP12 and KIR2DS2 (Sus scrofa)


name: KIR2DL2/3 interacting with HLA-C group 1 (Cw4) (Mus musculus)


name: EET(1) is hydrolysed to DHET(1) by EPHX2 (Dictyostelium discoideum)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Gallus gallus)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Dictyostelium discoideum)


name: Tyrosine is diiodinated (Drosophila melanogaster)


name: p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP (Drosophila melanogaster)


name: 3'-phosphoadenylyl sulfate(out) + adenosine 3',5'-bisphosphate(in) => 3'-phosphoadenylyl sulfate(in) + adenosine 3',5'-bisphosphate(out)


name: MLKL binds IP4, IP5 and IP6  (Bos taurus)


name: Autophosphorylation of PAK1 (Homo sapiens)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Bos taurus)


name: SYK activation by SRC (Canis familiaris)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Homo sapiens)


name: phthalate dioxygenase reductase activity


name: 15-cis-phytoene + A = AH2 + all-trans-phytofluene


name: LMF1,2 transport LIPC dimer from ER lumen to extracellular region (Xenopus tropicalis)


name: (E)-sinapate + ATP + H(+) <=> (E)-sinapoyl-AMP + diphosphate


name: KCNJs transport K+ from the extracellular region to cytosol (Bos taurus)


name: Defective B3GALTL does not transfer glucose to O-fucosyl-proteins (Homo sapiens)


name: H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate


name: REG3A binds bacterial phospholipids (Sus scrofa)


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Rattus norvegicus)


name: Association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)


name: glutathione S,S-dioxide + H(+) => O2 + S-sulfanylglutathione


name: GDIs block activation of RHOG (Drosophila melanogaster)


name: IRAK4 binds to activated TLR5 or 15. (Gallus gallus)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Danio rerio)


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Rattus norvegicus)


name: USP21 deubiquitinates GATA3,IL33 (Homo sapiens)


name: FMN-N(5)-peroxide + uracil => (Z)-3-ureidoacrylate + FMN-N(5)-oxide + 2 H(+)


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Plasmodium falciparum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: SREBP1A,1C,2 binds the FDFT1 promoter (Homo sapiens)


name: diphosphate + pentalenene => (2E,6E)-farnesyl diphosphate


name: ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Xenopus tropicalis)


name: Amyloid precursor proteins form ordered fibrils (Homo sapiens)


name: 4-hydroxy-L-proline(in) + H(+)(in) <=> 4-hydroxy-L-proline(out) + H(+)(out)


name: 7,9,9'-tri-cis-neurosporene + a quinone = 7,7',9,9'-tetra-cis-lycopene + a quinol


name: Monoubiquitinated PTEN translocates to the nucleus (Bos taurus)


name: double-stranded RNA adenosine deaminase activity


name: Formation of ORC(1-5) complex (Gallus gallus)


name: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + 2 H(+) => 3,4,5-trihydroxybenzoate + O2


name: 2 H(+) + H2O + N-carbamoylsarcosine = CO2 + NH4(+) + sarcosine


name: an N(6)-methyl-2'-O-methyladenosine in U2 snRNA + H(+) + S-adenosyl-L-homocysteine => a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+) => (Z)-glucotropeolin + H2O


name: Phosphorylation (Ser5) of RNA pol II CTD (Drosophila melanogaster)


name: ABCA7:Apo1A-mediated phospholipid efflux (Rattus norvegicus)


name: SLIT2 binds Dystroglycan (Gallus gallus)


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Sus scrofa)


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Homo sapiens)


name: N-(carboxyaminomethyl)urea + NH4(+) => H2O + methylenediurea


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-adenosine in mRNA + H2O <=> a 5'-end phospho-adenosine in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: NADP(+) + prenol <=> 3-methyl-2-butenal + H(+) + NADPH


name: 6-[(3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl]-2,4-dihydroxy-3-methylbenzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP] + S-adenosyl-L-homocysteine => (3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl-[ACP] + AH2 + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine


name: Release of eIF4E from the inactive eIF4E:4E-BP complex  (Bos taurus)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O => 2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: a (2S)-2-hydroxycarboxylate + NADP(+) <=> a 2-oxocarboxylate + H(+) + NADPH


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + a mannosylinositol-1-phospho-N-acyl-sphingoid base = a 1,2-diacyl-sn-glycerol + an inositol phosphomannosylnositol-1-phospho-N-acylsphingoid base


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2B (GRIN2B) (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Xenopus tropicalis)


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine <=> (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: (3S)-3-hydroxydodecanoyl-CoA + NAD(+) => 3-oxododecanoyl-CoA + H(+) + NADH


name: RIPK1 is cleaved by CASP8:FLIP(L) (Rattus norvegicus)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)


name: Galanin receptors can bind galanin (Canis familiaris)


name: ATP + diphosphate = ADP + H(+) + triphosphate


name: L-tyrosyl-[protein] + phosphate => H2O + O-phospho-L-tyrosyl-[protein]


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O => ADP-alpha-D-ribose 1''-phosphate + H(+)


name: (R)-carnitine + an acyl-CoA => CoA + O-acyl-(R)-carnitine


name: ethyl hexadecanoate + H2O = ethanol + H(+) + hexadecanoate


name: histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen (Homo sapiens)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Bos taurus)


name: Spherical HDL binds membrane-associated free cholesterol and phospholipids (Gallus gallus)


name: Formation of TRAP coactivator complex (Homo sapiens)


name: 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+) => 4-amino-5-aminomethyl-2-methylpyrimidine + H2O


name: a (3R)-3-[(carboxymethyl)amino]fatty acid + H(+) + holo-[ACP] <=> a (2E)-enoyl-[ACP] + glycine + H2O


name: Interleukin-23 binds interleukin-23 receptor (Mus musculus)


name: alpha-D-mannosyl-(1->3)-alpha-D-galactosyl-diphospho-di-trans,octa-cis-undecaprenol + GDP-alpha-D-mannose = alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: Activated FGFR4 binds SHC1 (Rattus norvegicus)


name: Activated FGFR2 phosphorylates FRS2 (Bos taurus)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Homo sapiens)


name: ATP + dehydroepiandrosterone 3-sulfate(in) + H2O = ADP + dehydroepiandrosterone 3-sulfate(out) + H(+) + phosphate


name: RAC2 binds effectors at the ER membrane (Mus musculus)


name: 4-hydroxybenzoate + ATP + H(+) + NADPH => 4-hydroxybenzaldehyde + AMP + diphosphate + NADP(+)


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA => (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H2O


name: IGF2BP1 binds specific RNAs (Homo sapiens)


name: 4-nitrophenol + H(+) + NADPH + O2 = 4-nitrocatechol + H2O + NADP(+)


name: 4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + FMNH2 + O2 = 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + FMN + H(+) + H2O


name: "4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase"


name: Squalene is oxidized to its epoxide (Xenopus tropicalis)


name: Group 3 - Selective Cl- transport (Sus scrofa)


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)


name: choloyl-CoA + H2O = adenosine 3',5'-bisphosphate + 2 H(+) + S-choloyl-4'-phosphopantetheine


name: USP8 deubiquitinates RNF128 (Mus musculus)


name: devancoaminyl-vancomycin + dTDP-beta-L-vancosamine => dTDP + epivancomycin + H(+)


name: (R)-prunasin + H2O => D-glucose + mandelonitrile


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Canis familiaris)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Canis familiaris)


name: a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose <=> a globoside GalGb4Cer (d18:1(4E)) + H(+) + UDP


name: (d)AMP + ATP <=> (d)ADP + ADP (AK1) (Drosophila melanogaster)


name: (13Z)-3-oxodocosenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(13Z)-docosenoyl-CoA + NADP(+)


name: Formation of the Spliceosomal Pre-B complex (Homo sapiens)


name: an acyl-CoA + sn-glycerol 3-phosphocholine <=> a 1-acyl-sn-glycero-3-phosphocholine + CoA


name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 (Homo sapiens)


name: 2-(9Z-octadecenoyl)-glycerol + eicosanoyl-CoA => 1-eicosanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA = [N,O(9)-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes (Sus scrofa)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(34-hydroxytetratriacontenoyl)-sphing-4-enine => a diacylglycerol + an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontenoyl)-sphing-4-enine


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: adenosine in double-stranded RNA + H(+) + H2O <=> inosine in double-stranded RNA + NH4(+)


name: glycine betaine + L-homocysteine => L-methionine + N,N-dimethylglycine


name: Peptide transfer from P-site to A-site (peptide bond formation) (Homo sapiens)


name: 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: decanoyl-[ACP] + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> dec-9-ynoyl-[ACP] + 4 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Schizosaccharomyces pombe)


name: H2O + O2 + propane-1,3-diamine <=> 3-aminopropanal + H2O2 + NH4(+)


name: ECE1 cleaves EDN1(53-90) (Rattus norvegicus)


name: L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Rattus norvegicus)


name: (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + AH2 + O2 => (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + A + 2 H2O


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA <=> 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: PRMT6 methylates histone H2A arginine-30 (H2AR29) (Sus scrofa)


name: GNRHR binds GNRHR peptide agonists (Caenorhabditis elegans)


name: P2RY12 binds P2RY12 antagonists (Xenopus tropicalis)


name: AH2 + N-acyl-15-methylhexadecasphinganine + O2 = A + 2 H2O + N-acyl-15-methylhexadecasphing-4-enine


name: 1-hydroxylimonen-2-one + H(+) + NADPH + O2 <=> 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: SLC25A10 mediates exchange of malate and phosphate (Dictyostelium discoideum)


name: HEXA cleaves the terminal GalNAc from DS (Mus musculus)


name: Expression of NAMPT (NamPRT, PBEF, Visfatin) (Homo sapiens)


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Rattus norvegicus)


name: 3-methyl-2-oxobutanoate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] <=> CO2 + N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]


name: an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H(+)


name: LRTOMT transfers Met to DA, forming 3MT (Bos taurus)


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Bos taurus)


name: 1alpha-hydroxytestosterone + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + testosterone


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Sus scrofa)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Bos taurus)


name: MAPK6 is degraded by the 26S proteasome (Caenorhabditis elegans)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Schizosaccharomyces pombe)


name: a 5'-end adenosine-5'-diphospho-5'-(2'-deoxyribonucleoside)-DNA + H2O => a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + AMP + 2 H(+)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Danio rerio)


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Danio rerio)


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Caenorhabditis elegans)


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Plasmodium falciparum)


name: LZTFL1 binds the BBSome and prevents its traffic to the cilium (Bos taurus)


name: Recruitment of ITK to SLP-76 (Mus musculus)


name: n H(+)(out) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(out) => n H(+)(in) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(in)


name: ATP + H2O + L-ornithine(out) => ADP + H(+) + L-ornithine(in) + phosphate


name: Degradation of multiubiquitinated Cdh1 (Mus musculus)


name: (25R)-3beta-hydroxy-5-cholesten-26-al + H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3beta-hydroxy-5-cholestenoate + H2O + 2 oxidized [adrenodoxin]


name: PP2A dephosphorylates RAF1 (Drosophila melanogaster)


name: Activation of TWIK-related K+ channel (TREK) (Mus musculus)


name: (S)-beta-macrocarpene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: DPAn-6 SPMs translocate from cytosol to extracellular region (Homo sapiens)


name: a quinone + glutathione + H(+) + hydrogen sulfide => a quinol + S-sulfanylglutathione


name: MRN complex binds DNA double strand breaks (Sus scrofa)


name: 1D-myo-inositol 6-phosphate + H2O = myo-inositol + phosphate


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-tryptophyl-[protein] => acetyl-CoA + N-terminal L-methionyl-L-tryptophyl-[protein]


name: NR1H2,3 binds the CETP gene (Homo sapiens)


name: 2-(prostaglandin H2)-sn-glycero-3-phosphocholine + A + H2O => 2-(prostaglandin G2)-sn-glycero-3-phosphocholine + AH2


name: RAC1 GDIs block activation of RAC1 (Caenorhabditis elegans)


name: G-proteins dissociate from plasma-membrane estrogen receptors (Drosophila melanogaster)


name: GLI proteins bind SUFU (Canis familiaris)


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Danio rerio)


name: (2E,6E)-farnesyl diphosphate => diphosphate + gamma-curcumene


name: 1,2-dichloroethane + H2O = 2-chloroethanol + chloride + H(+)


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Caenorhabditis elegans)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Homo sapiens)


name: PELI1 ubiquitinates RIPK3 at K363 (Homo sapiens)


name: Formation of MCM2-7 complex (Xenopus tropicalis)


name: Association of cell cycle proteins with the APC/C:Cdh1 complex (Bos taurus)


name: 1-decanoyl-3-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-decanoylglycerol


name: Activation and dimerization of c-JUN in the nucleus (Gallus gallus)


name: LAIR2 binds collagen (Xenopus tropicalis)


name: NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP (Canis familiaris)


name: fatty acid transmembrane transporter activity


name: ERBB2 binds TKIs (Drosophila melanogaster)


name: Caspase-mediated cleavage of occludin (Bos taurus)


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Gallus gallus)


name: Cho is acetylated to AcCho by CHAT (Danio rerio)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Schizosaccharomyces pombe)


name: 3-oxohexadecanedioyl-CoA + H(+) + NADH => (3S)-hydroxyhexadecanedioyl-CoA + NAD(+)


name: dodecanoyl-CoA + H(+) + malonyl-[ACP] => 3-oxotetradecanoyl-[ACP] + CO2 + CoA


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Sus scrofa)


name: limonene-1,2-diol + NAD(+) = 1-hydroxylimonen-2-one + H(+) + NADH


name: (1S,4R)-1-hydroxylimonen-2-one + NADPH + O2 => (3R)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)


name: VRK1/VRK2 phosphorylate BANF1 (Bos taurus)


name: dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-adenosyl-L-methionine = dTDP-D-ravidosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: RHOD:GTP translocates to the endosome membrane (Caenorhabditis elegans)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Sus scrofa)


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)


name: Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Xenopus tropicalis)


name: Association of DFF with alpha:beta importin (Gallus gallus)


name: H(+) + NADPH + trypanothione disulfide => NADP(+) + trypanothione


name: IL2 gene expression is stimulated by RUNX1 and NFATC2 and repressed by FOXP3 (Homo sapiens)


name: SUMOylation of HDAC1 with SUMO1 (Xenopus tropicalis)


name: COASY transfers an adenylyl group from ATP to PPANT (Saccharomyces cerevisiae)


name: AKT1 phosphorylates eNOS (Plasmodium falciparum)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)


name: ROBO2 gene transcription is stimulated by HOXA2 and inhibited by LHX2 (Homo sapiens)


name: (R)-nicotine + A + H2O = (R)-6-hydroxynicotine + AH2


name: (3E)-2-oxohex-3-enedioate + H(+) <=> 2-oxopent-4-enoate + CO2


name: Kinesins move along microtubules consuming ATP (Drosophila melanogaster)


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA = (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA + H2O


name: (S)-4-hydroxy-2-oxohexanoate = propanal + pyruvate


name: GAPDH tetramers reduce 1,3BPG to GA3P (Canis familiaris)


name: Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Sus scrofa)


name: IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Mus musculus)


name: 6-phospho-beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein] => D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein]


name: PDE3A inhibitors bind PDE3A (Bos taurus)


name: GBF1 recruits ARF:GDP to the Golgi (Schizosaccharomyces pombe)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Sus scrofa)


name: SUMOylation of NPM1 with SUMO2,3 (Bos taurus)


name: CTP + H(+) + Mo-molybdopterin <=> diphosphate + Mo-molybdopterin cytosine dinucleotide


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Xenopus tropicalis)


name: ITPA hydrolyses dITP to dIMP (Rattus norvegicus)


name: Dissociation of Cdc20 from APC/C complex (Dictyostelium discoideum)


name: Phosphorylation of AXN and APC by DCO (Drosophila melanogaster)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Rattus norvegicus)


name: BCKDH transfers CoA group from CoA-SH to BCAAs (Drosophila melanogaster)


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Xenopus tropicalis)


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Bos taurus)


name: SLC25A10 mediates exchange of malate and phosphate (Mus musculus)


name: CBL dissociates from ubiquitinated p-SPRY2 (Bos taurus)


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Xenopus tropicalis)


name: ALK binds ligand midkine (MDK) (Danio rerio)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Mus musculus)


name: flavokermesate + UDP-alpha-D-glucose => flavokermesate 7-C-beta-D-glucoside + 2 H(+) + UDP


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Danio rerio)


name: 3'-phosphoadenylyl sulfate + an aliphatic (Z)-desulfo-glucosinolate => a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + adenosine 3',5'-bisphosphate + H(+)


name: TRiC/CCT binds unfolded G-protein beta subunit (Caenorhabditis elegans)


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Caenorhabditis elegans)


name: acetyl-CoA + 6 H(+) + 6 malonyl-CoA = 6 CO2 + 7 CoA + 2 H2O + nor-toralactone


name: diphthine methyl ester-[translation elongation factor 2] + 3 H(+) + 4 S-adenosyl-L-homocysteine => 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Gallus gallus)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Schizosaccharomyces pombe)


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Xenopus tropicalis)


name: acetyl-CoA + N(6)-hydroxy-L-lysine <=> CoA + N(6)-acetyl-N(6)-hydroxy-L-lysine


name: ATP + glycerol <=> ADP + H(+) + sn-glycerol 3-phosphate


name: 2-methoxybenzaldehyde + hydrogen cyanide = (2S)-2-hydroxy-2-(2-methoxyphenyl)acetonitrile


name: Telomere shortening during replicative exhaustion (Bos taurus)


name: NUDT16 hydrolyses IDP to IMP (Mus musculus)


name: (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 oxidized [adrenodoxin]


name: a 1,2-diacyl-sn-glycerol + H2O <=> a fatty acid + a monoacylglycerol + H(+)


name: SUMOylation of TOP1 with SUMO1 (Bos taurus)


name: TPI1 isomerizes GA3P to DHAP (Canis familiaris)


name: NCOA1 recruits EP300 to TGFA promoter (Canis familiaris)


name: Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)


name: Interaction of IRF9 with p-STAT2:p-STAT1 (Rattus norvegicus)


name: 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: H(+)(in) + L-cystine(in) => H(+)(out) + L-cystine(out)


name: ent-kaur-16-ene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> ent-kaur-16-en-19-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine <=> 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP


name: Trimerization of the FASL:FAS receptor complex (Gallus gallus)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Gallus gallus)


name: Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Sus scrofa)


name: GPR31 is a receptor for 12(S)-HETE (Mus musculus)


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Homo sapiens)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Homo sapiens)


name: Phosphorylation of SHP2 by SFKs (Rattus norvegicus)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Bos taurus)


name: NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Rattus norvegicus)


name: Phosphorylation of STAT1 at Ser727 (Homo sapiens)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Xenopus tropicalis)


name: Formation of MCM2-7 complex (Schizosaccharomyces pombe)


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 (Danio rerio)


name: Casein kinase II phosphorylates STARD10 (Homo sapiens)


name: D-lysine + H2O + O2 => 6-amino-2-oxohexanoate + H2O2 + NH4(+)


name: (2S,3S)-3-methylphenylalanine + 2-oxoglutarate = (3S)-2-oxo-3-phenylbutanoate + L-glutamate


name: 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + archaeosine(15) in tRNA + 2 H(+) + L-1-piperideine-6-carboxylate + L-methionine


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Drosophila melanogaster)


name: CBL recruits CIN85:endophilin to ubiquitinated MET (Mus musculus)


name: an inositol-1-phosphoceramide + H2O = 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)


name: a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O <=> a neolactoside nLc4Cer(d18:1(4E)) + L-fucose


name: 2 AH2 + 2 archaeol + 4 S-adenosyl-L-methionine = 4 5'-deoxyadenosine + 2 A + glycerol dibiphytanyl glycerol tetraether + 4 H(+) + 4 L-methionine


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: "cellulose 1,4-beta-cellobiosidase (non-reducing end)"


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Mus musculus)


name: ADH5 oxidises S-HMGSH to S-FGSH (Homo sapiens)


name: CoA + H(+) + N-acyl-15-methylhexadecasphing-4-enine => 15-methylhexadecasphing-4-enine + a fatty acyl-CoA


name: TRAF6 is auto-ubiquitinated (Rattus norvegicus)


name: CYP21A2 21-hydroxylates PROG (Canis familiaris)


name: Autocatalytic phosphorylation of FGFR2c (Homo sapiens)


name: 1,4-benzoquinone + H2O + NADP(+) + nitrite => 4-nitrophenol + H(+) + NADPH + O2


name: Activation of Calcineurin (Homo sapiens)


name: pelargonidin + UDP-alpha-D-galactose <=> pelargonidin 3-O-beta-D-galactoside betaine + UDP


name: 3-oxooctadecanoyl-CoA + H(+) + NADPH = (3R)-hydroxyoctadecanoyl-CoA + NADP(+)


name: (E)-feruloylacetyl-CoA + CO2 + CoA => (E)-feruloyl-CoA + H(+) + malonyl-CoA


name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 (Homo sapiens)


name: IDS hydrolyses Heparan sulfate chain(5) (Homo sapiens)


name: (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O => (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate


name: Conversion of Glycerol to Glycerol-3-phosphate (Bos taurus)


name: FGFR2c binds to FGF (Drosophila melanogaster)


name: ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate => 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate


name: IQGAP1 binds CLIP1 and microtubules (Dictyostelium discoideum)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Gallus gallus)