name: Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E+ Cofactor C-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C (Homo sapiens)


name: Activation of PP2A by Xylulose-5-phosphate (Homo sapiens)


name: SMPD4 hydrolyzes sphingomyelin (ER membrane) (Bos taurus)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Rattus norvegicus)


name: 7,8-dihydroxycoumarin + S-adenosyl-L-methionine => 7-hydroxy-8-methoxycoumarin + H(+) + S-adenosyl-L-homocysteine


name: 1-propanol + NAD(+) <=> H(+) + NADH + propanal


name: Recruitment of STATs (Xenopus tropicalis)


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Rattus norvegicus)


name: HIPK2 phosphorylates RUNX1 and EP300 (Gallus gallus)


name: cytidine(out) + Na(+)(out) = cytidine(in) + Na(+)(in)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Sus scrofa)


name: Homodimerization of ERBB4 (Gallus gallus)


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Sus scrofa)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Sus scrofa)


name: Dephosphorylation of Gab1 by SHP2 (Canis familiaris)


name: H(+) + soyasaponin I + UDP => soyasaponin III + UDP-beta-L-rhamnose


name: 3-(4-hydroxyphenyl)pyruvate + H(+) + NADH => (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+)


name: H(+) + NADPH + neopatulin <=> (E)-ascladiol + NADP(+)


name: TP73 tetramer translocates to the nucleus (Danio rerio)


name: alpha,alpha-trehalose 6-phosphate(in) + L-histidyl-[protein] => alpha,alpha-trehalose(out) + N(pros)-phospho-L-histidyl-[protein]


name: CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer binds SRC family kinases FYN,HCK,SRC,YES1 (Homo sapiens)


name: L-tryptophan(out) + Na(+)(out) => L-tryptophan(in) + Na(+)(in)


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Xenopus tropicalis)


name: 3-hydroxyanthranilate + H(+) + L-alanine => 3-hydroxy-L-kynurenine + H2O


name: glycerol + H(+) + octadecanoate => 1-octadecanoylglycerol + H2O


name: ZnT8 transports zinc into the Golgi apparatus (Homo sapiens)


name: PRTPRF, PTPRS, PTPRD bind LRRC4B (Rattus norvegicus)


name: asnovolin I + S-adenosyl-L-methionine = asnovolin K + S-adenosyl-L-homocysteine


name: (9Z)-hexadecenoate + 1,3-di-(9Z)-hexadecenoylglycerol + H(+) => 1,2,3-tri-(9Z)-hexadecenoylglycerol + H2O


name: (6Z)-octenoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(6Z-octenoyl)-4'-phosphopantetheine


name: vasoactive intestinal polypeptide receptor binding


name: (3S)-2-oxo-3-phenylbutanoate + H(+) + S-adenosyl-L-homocysteine => 3-phenylpyruvate + S-adenosyl-L-methionine


name: 4',4'-dihydroxyechinenone = canthaxanthin + H2O


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Mus musculus)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: demethylmacrocin + S-adenosyl-L-methionine => H(+) + macrocin + S-adenosyl-L-homocysteine


name: CDK1 phosphorylates MAPK6 (Canis familiaris)


name: structural constituent of adult chitin-based cuticle


name: 2-oxoglutarate + L-isoleucine + O2 => (4S)-4-hydroxy-L-isoleucine + CO2 + succinate


name: 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + A => (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA + AH2


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Caenorhabditis elegans)


name: Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Mus musculus)


name: cAMP induces dissociation of inactive PKA tetramers (Sus scrofa)


name: 3-hydroxy-L-aspartyl-[protein] + CO2 + succinate => 2-oxoglutarate + L-aspartyl-[protein] + O2


name: SPN27A binds to and inhibits EA protease activity (Drosophila melanogaster)


name: diphosphate + H2O <=> H(+) + 2 phosphate


name: prosolanapyrone III <=> (-)-solanapyrone A


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Bos taurus)


name: D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity


name: USP3,SAGA deubiquitinate Histone H2A,H2B (Rattus norvegicus)


name: phosphorylated perilipin + H2O -> perilipin + orthophosphate (Homo sapiens)


name: Aquaporin-1 passively transports water out of cell (Dictyostelium discoideum)


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Homo sapiens)


name: PDPK1 phosphorylates AKT2 (Caenorhabditis elegans)


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Gallus gallus)


name: 11-cis-retinol + tetradecanoyl-CoA => 11-cis-retinyl tetradecanoate + CoA


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Gallus gallus)


name: PTK2 autophosphorylates (Canis familiaris)


name: SYK autophosphorylates at the activated BCR (Sus scrofa)


name: 2-methylpropanal + H(+) + NADPH + NH4(+) => 2-methylpropan-1-amine + H2O + NADP(+)


name: p-PKR dimer phosphorylates PTPN2 (Drosophila melanogaster)


name: H(+) + pterostilbene + S-adenosyl-L-homocysteine => 3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-methionine


name: RFC dissociates after sliding clamp formation on the C-strand of the telomere (Homo sapiens)


name: Kinesins move along microtubules consuming ATP (Xenopus tropicalis)


name: ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine => ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Schizosaccharomyces pombe)


name: H(+) + N-hydroxy-2-acetamidofluorene + NADPH => 2-acetamidofluorene + H2O + NADP(+)


name: ADRB2 in ADRB2:GRK complex is phosphorylated (Mus musculus)


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Mus musculus)


name: 2-oxoglutarate(out) + citrate(in) => 2-oxoglutarate(in) + citrate(out)


name: NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Mus musculus)


name: sBAFF,sAPRIL binds TACI,BCMA (Canis familiaris)


name: SREBP1A,1C,2 binds the FDPS promoter (Homo sapiens)


name: [DsbD protein]-disulfide + [protein]-dithiol <=> [DsbB protein]-dithiol + [protein]-disulfide


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Xenopus tropicalis)


name: PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Sus scrofa)


name: ARL1:GTP binds SCOC (Xenopus tropicalis)


name: alfacalcidol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => calcitriol + H2O + 2 oxidized [adrenodoxin]


name: WWTR1:p-2S-SMAD2,3:SMAD4 binds SMAD7 gene promoter (Homo sapiens)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Drosophila melanogaster)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Gallus gallus)


name: COX15 transforms heme O to heme A (Plasmodium falciparum)


name: N-acetylindoxyl + O2 => H2O + N-acetylisatin


name: PCSK9:LDLR bind to Clathrin (Homo sapiens)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Dictyostelium discoideum)


name: butanoyl-CoA + hexan-1-ol => CoA + hexyl butanoate


name: ARSB hydrolyses C4S/C6S chains (Sus scrofa)


name: 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O => 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA => 3-(methylsulfanyl)acryloyl-CoA + H2O


name: a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: O-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate + H(+)


name: SLC2A9 transports Fru, Glc, urate (Xenopus tropicalis)


name: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate => 3-carboxy-cis,cis-muconate + H(+)


name: H2O + N-formimidoyl-L-glutamate => N-formyl-L-glutamate + NH4(+)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Rattus norvegicus)


name: p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)


name: diphosphate + ent-isokaurene => ent-copalyl diphosphate


name: Formation of the closed pre-initiation complex (Dictyostelium discoideum)


name: holo-[peptidyl-carrier protein] + L-threonyl-5'-AMP = AMP + L-threonyl-[peptidyl-carrier protein]


name: S-methyl-5-thio-D-ribulose 1-phosphate <=> S-methyl-1-thio-D-xylulose 5-phosphate


name: Sprouty sequesters CBL away from active EGFR (Gallus gallus)


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Caenorhabditis elegans)


name: cyclohex-1-ene-1-carbonyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> cyclohexa-1,5-diene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]


name: (20S)-ginsenoside Rd + 2 H2O <=> (20S)-ginsenoside C-K + 2 D-glucose


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Schizosaccharomyces pombe)


name: NGEF exchanges GTP for GDP on RHOA (Sus scrofa)


name: Phosphorylated YBX1 translocates to the nucleus (Xenopus tropicalis)


name: hexanal + NADP(+) <=> (E)-hex-2-enal + H(+) + NADPH


name: [phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + H(+) + methanol


name: Interaction of Bcl10 to CARMA1 (Canis familiaris)


name: "Lyases acting on amides, amidines, etc"


name: Retrograde COPI vesicles bind kinesin and microtubules (Caenorhabditis elegans)


name: (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate => (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate + ATP + CoA


name: CHD1L is recruited to GG-NER site (Canis familiaris)


name: H(+) + N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: USP25 deubiquitinates DDX58 (Sus scrofa)


name: phosphoenolpyruvate + ADP => pyruvate + ATP (Plasmodium falciparum)


name: 2 H(+)(in) + histamine(out) => 2 H(+)(out) + histamine(in)


name: (S)-3-(imidazol-5-yl)lactate + NAD(+) => 3-(imidazol-5-yl)pyruvate + H(+) + NADH


name: a 2-oxocarboxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid


name: H2O + N,N'-diacetylchitobiose => 2 N-acetyl-D-glucosamine


name: CaMKII binds activated NMDA receptor (Homo sapiens)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Bos taurus)


name: H(+) + jasmonate + NADPH + O2 = (1R,2R)-12-hydroxyjasmonate + H2O + NADP(+)


name: MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Gallus gallus)


name: Cu(+)(out) + H(+) + monodehydro-L-ascorbate radical(in) => Cu(2+)(out) + L-ascorbate(in)


name: 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + NADP(+)


name: an alcohol + H(+) + sn-glycerol 3-phosphate => a sn-glycero-3-phosphodiester + H2O


name: formate + 2 H(+) + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite => O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase]


name: Cytosolic DUSPs dephosphorylate MAPKs (Xenopus tropicalis)


name: hexadecanoyl-CoA + tetradecan-1-ol => CoA + tetradecanyl hexadecanoate


name: trans-Golgi Network Vesicle Scission (Homo sapiens)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Bos taurus)


name: 2 H2O + phenylpropanonitrile => 3-phenylpropanoate + NH4(+)


name: H(+) + phosphoenolpyruvate => 3-phosphonopyruvate


name: (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(2'-(9Z-octadecenoyl)-3'-sn-glycerol) + H2O = (9Z)-octadecenoate + (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-sn-glycerol) + H(+)


name: ethanethiol + NH4(+) + pyruvate => H2O + S-ethyl-L-cysteine


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Danio rerio)


name: L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Plasmodium falciparum)


name: (2E)-eicosenoyl-CoA + H(+) + NADH <=> eicosanoyl-CoA + NAD(+)


name: an acyl-CoA + lanosterol <=> CoA + lanosteryl ester


name: taurine + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoyl-taurine


name: acetate + ATP + cytidine(34) in elongator tRNA(Met) = AMP + diphosphate + N(4)-acetylcytidine(34) in elongator tRNA(Met)


name: L-pipecolate(in) + Na(+)(in) <=> L-pipecolate(out) + Na(+)(out)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Drosophila melanogaster)


name: acetyl-CoA + D-glutamine = CoA + H(+) + N-acetyl-D-glutamine


name: SALMs1-3 bind each other in cis interactions (Xenopus tropicalis)


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Danio rerio)


name: acetyl-CoA + streptothricin D = CoA + H(+) + N(beta)-acetylstreptothricin D


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH => cholate + NADP(+)


name: S1PR1 binds S1PR1 agonists (Danio rerio)


name: Phosphorylation of APC component of the destruction complex (Rattus norvegicus)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Mus musculus)


name: allodeoxycholoyl-CoA + ursodeoxycholate => allodeoxycholate + ursodeoxycholoyl-CoA


name: NPAS4 stimulates IQSEC3 gene expression (Homo sapiens)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Homo sapiens)


name: H2O + N-(9Z-octadecenoyl)-L-methionine = (9Z)-octadecenoate + L-methionine


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Rattus norvegicus)


name: deoxycholoyl-CoA + ursodeoxycholate = deoxycholate + ursodeoxycholoyl-CoA


name: 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA => 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: H2O + kojibiose = alpha-D-glucose + D-glucose


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Plasmodium falciparum)


name: GTP + L-seryl-[protein] => GDP + H(+) + O-phospho-L-seryl-[protein]


name: RUNX1 mRNA translation is inhibited by miR-17, miR-18a, miR-20a, miR-27a, miR-106a, miR-215, miR-302b, miR-378 and miR-675 (Homo sapiens)


name: a ganglioside GT1b (d18:1(4E)) + CMP + H(+) => a ganglioside GD1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: Addition of the third nucleotide on the nascent transcript (Schizosaccharomyces pombe)


name: Translocation of PKC theta to plasma membrane (Drosophila melanogaster)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Caenorhabditis elegans)


name: ZFP36 (TTP) recruits RNA degradation activities (Dictyostelium discoideum)


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Mus musculus)


name: (E)-4-coumaraldehyde + H(+) + NADPH => (E)-4-coumaroyl alcohol + NADP(+)


name: cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (22R)-hydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: InlB-activated MET phosphorylates CBL (Homo sapiens)


name: prenylated protein tyrosine phosphatase activity


name: CMP(out) + UMP(in) => CMP(in) + UMP(out)


name: salicylic acid glucosyltransferase (ester-forming) activity


name: AKT1 phosphorylates eNOS (Gallus gallus)


name: 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = a fatty acid + acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+)


name: nucleotide-sulfate transmembrane transporter activity


name: 1,3,7-trimethylurate + H(+) + NADH + O2 <=> 1,3,7-trimethyl-5-hydroxyisourate + H2O + NAD(+)


name: NAD(+) + trans-4-hydroxycyclohexanecarboxylate => 4-oxocyclohexanecarboxylate + H(+) + NADH


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[protein] => acetyl-CoA + N-terminal L-methionyl-[protein]


name: H2O + N-(tetracosanoyl)-sphing-4-enine-1-phosphocholine <=> H(+) + N-tetracosanoyl-sphing-4-enine + phosphocholine


name: Factor Xa inhibitors binds Xa (Xenopus tropicalis)


name: L-alanine + sulfoacetaldehyde => pyruvate + taurine


name: STAT4 binds p-Y-IL23R in IL23:IL23 receptor (Homo sapiens)


name: E2F7 forms homodimers (Canis familiaris)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Bos taurus)


name: Formation of Processive Complex (Canis familiaris)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: CCND1 recruits HDAC4 to RUNX3 (Drosophila melanogaster)


name: NTRK2-phosphorylated FRS2 binds GRB2 (Mus musculus)


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Rattus norvegicus)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Plasmodium falciparum)


name: a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GM2 + H(+) + UDP


name: 2-(9Z-octadecenoyl)-glycerol + H2O <=> (9Z)-octadecenoate + glycerol + H(+)


name: an N(2)-acyl-L-glutamine + H2O => a carboxylate + L-glutamine


name: NEXT3 is cleaved to produce NICD3 (Homo sapiens)


name: CYP17A1 17-hydroxylates P4 to 17aHPROG (Rattus norvegicus)


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Danio rerio)


name: 15-methylhexadecasphing-4-enine 1-phosphate <=> (2E)-13-methyltetradecenal + phosphoethanolamine


name: Collagen type III degradation by MMP15 (Xenopus tropicalis)


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Xenopus tropicalis)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Gallus gallus)


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Mus musculus)


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Plasmodium falciparum)


name: LIG1 binds POLB at long-patch BER site (Bos taurus)


name: CDH11 associates with catenins (Mus musculus)


name: hydroxyclavatol ethyl ether => ethanol + o-quinone methide


name: glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 (Sus scrofa)


name: apo-[methylmalonyl-CoA:pyruvate carboxytransferase] + ATP + biotin => AMP + diphosphate + H(+) + holo-[methylmalonyl-CoA:pyruvate carboxytransferase]


name: SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp (Drosophila melanogaster)


name: diphosphate + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] => GTP + L-histidyl-[RNA ligase]


name: TRAF6 is auto-ubiquitinated (Mus musculus)


name: DCP1-DCP2 complex decaps mRNA (Danio rerio)


name: alpha-D-glucose 1-phosphate + CTP + H(+) => CDP-D-glucose + diphosphate


name: ASAP1 stimulates GTPase activity of ARF4 (Homo sapiens)


name: ATXN3 family cleave Ub chains (Drosophila melanogaster)


name: 2-oxobutanoate + L-kynurenine <=> (2S)-2-aminobutanoate + 4-(2-aminophenyl)-2,4-dioxobutanoate


name: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) => diphosphate + DNA(n+1)


name: 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine <=> 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: 1-heptadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-heptadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: (13E)-labda-7,13-dien-15-ol + diphosphate => (13E)-labda-7,13-dien-15-yl diphosphate + H2O


name: dehydroepiandrosterone 3-sulfate(out) + glutarate(in) => dehydroepiandrosterone 3-sulfate(in) + glutarate(out)


name: G alpha (q) inhibits PI3K alpha (Bos taurus)


name: Recognition and Binding of Core Promoter Elements by TFIID (Caenorhabditis elegans)


name: H2O + sphinga-4E,14Z-dienine-1-phosphate = phosphate + sphinga-4E,14Z-dienine


name: Nsp3, nsp4, and nsp6 produce replicative organelles (Homo sapiens)


name: Sec-tRNA(Sec) binds to EEFSEC:GTP (Homo sapiens)


name: 5-aminomethyl-dUMP in DNA + acetyl-CoA => 5-acetylaminomethyl-dUMP in DNA + CoA + H(+)


name: (15S)-hydroperoxy-(11Z,13E)-eicosadienoate + 2 glutathione = (15S)-hydroxy-(11Z,13E)-eicosadienoate + glutathione disulfide + H2O


name: lithocholate + PAPS => lithocholate sulfate + PAP (Drosophila melanogaster)


name: 17-beta-hydroxysteroid dehydrogenase (NAD+) activity


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Caenorhabditis elegans)


name: 3-dimethylallyl-4-hydroxyphenylpyruvate + O2 => 3-dimethylallyl-4-hydroxymandelate + CO2


name: PRKACA phosphorylates PLN (Rattus norvegicus)


name: Phosphorylation of Platelet Sec-1 (Schizosaccharomyces pombe)


name: RAC1 GDIs block activation of RAC1 (Rattus norvegicus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: 7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 2'-phosphate + H(+)


name: (3R)-3-amino-3-phenylpropanoyl-CoA + baccatin III => 3'-N-debenzoyl-2'-deoxytaxol + CoA


name: IGF1R phosphorylates SHC1 (Rattus norvegicus)


name: JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Rattus norvegicus)


name: H(+) + NADPH + O2 + phenylacetone = benzyl acetate + H2O + NADP(+)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Sus scrofa)


name: Fgr may phosphorylate p38 MAPK (Gallus gallus)


name: Autophosphorylation of PDGF alpha receptors (Gallus gallus)


name: (S)-benzoin + NADP(+) <=> benzil + H(+) + NADPH


name: Hemes bind to CLEC1B dimer (Mus musculus)


name: FOLR2 transports FOLA from extracellular region to cytosol (Bos taurus)


name: hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 2-(9Z-octadecenoyl)-glycerol + ATP


name: H2O + kynurenate + L-tyrosine => 3-(4-hydroxyphenyl)pyruvate + L-kynurenine


name: heme B transmembrane transporter activity


name: AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]


name: Caspase-mediated cleavage of gelsolin (Rattus norvegicus)


name: ABC7, mABC1 and mABC2 mediate heme transport (Schizosaccharomyces pombe)


name: PTK6 phosphorylates KHDRBS3 (Homo sapiens)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Mus musculus)


name: Superoxide reduces cytochrome c (Saccharomyces cerevisiae)


name: Endocytosis of protein 3a (Homo sapiens)


name: beta-D-Gal-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP => N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Homo sapiens)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Canis familiaris)


name: (2R,3S)-piscidate + (E)-feruloyl-CoA = cimicifugate E + CoA


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Drosophila melanogaster)


name: (1'S)-averantin + NADP(+) = H(+) + NADPH + norsolorinic acid


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Xenopus tropicalis)


name: Addition of galactose by beta 4-galactosyltransferases (Mus musculus)


name: ERCC1:XPF cleaves flaps generated by SSA (Bos taurus)


name: FAD + glutaryl-CoA + 2 H(+) <=> (2E)-butenoyl-CoA + CO2 + FADH2


name: Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements (Rattus norvegicus)


name: dopamine neurotransmitter receptor activity, coupled via Gs


name: ACSF2 ligates CoA-SH to MCFA (Homo sapiens)


name: L-arginine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) = L-arginine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: 3-oxododecanoyl-CoA + H2O <=> 3-oxododecanoate + CoA + H(+)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate <=> 1D-myo-inositol 1,3,4,5-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate


name: Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide (Drosophila melanogaster)


name: (6-hydroxyhexanoyl)n-1 + 6-hydroxyhexanoate + H(+) => (6-hydroxyhexanoyl)n + H2O


name: acetate + CoA + H(+) => acetyl-CoA + H2O


name: H(+) + NADPH + O2 + phenylacetone <=> benzyl acetate + H2O + NADP(+)


name: CO2 + succinate + trans-4-hydroxy-L-proline => 2-oxoglutarate + L-proline + O2


name: RUNX1 binds the SWI/SNF complex (Sus scrofa)


name: CoA + H(+) + olivetolate => 3,5,7-trioxododecanoyl-CoA


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Homo sapiens)


name: PDCL promotes G-protein beta 5 folding (Canis familiaris)


name: Phosphorylated MAPKs translocate into the nucleus (Bos taurus)


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Bos taurus)


name: 4-nitrophenyl phosphate + H2O => 4-nitrophenol + H(+) + phosphate


name: alpha-D-mannose 1-phosphate + GDP-alpha-D-glucose <=> alpha-D-glucose 1-phosphate + GDP-alpha-D-mannose


name: The p75NTR:NgR:MDGI binds RHOA-GDI (Bos taurus)


name: SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region (Gallus gallus)


name: acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18]


name: guanosine + phosphate <=> alpha-D-ribose 1-phosphate + guanine


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + hexadecanoyl-CoA <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + zealexin A1 => (S)-beta-macrocarpene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: RUNX1, FOXP3 and NFATC2 bind the IL2 gene promoter (Homo sapiens)


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Homo sapiens)


name: fumarate(out) + succinate(in) => fumarate(in) + succinate(out)


name: Activated NTRK3 binds SRC (Canis familiaris)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Canis familiaris)


name: dimethylallyl diphosphate + phlorisovalerophenone = 4-prenylphlorisovalerophenone + diphosphate


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Rattus norvegicus)


name: Phosphorylated SHC recruits GRB2:SOS1 (Rattus norvegicus)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Canis familiaris)


name: a 3-oxoacyl-CoA + succinate => a 3-oxo acid + succinyl-CoA


name: RHOV binds effectors at the plasma membrane (Schizosaccharomyces pombe)


name: Initial activation of proMMP13 by plasmin and trypsin (Gallus gallus)


name: mTORC1 phosphorylates AKT1S1 (Danio rerio)


name: YWHAB dimer dissociates from dephosphorylated RAF (Gallus gallus)


name: Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Mus musculus)


name: PIN1 binds phosphorylated PIP4K2B (Saccharomyces cerevisiae)


name: (4R)-ipsdienol + NADP(+) <=> H(+) + ipsdienone + NADPH


name: [(1->2)-beta-D-glucosyl](n)(out) + ADP + H(+) + phosphate => [(1->2)-beta-D-glucosyl](n)(in) + ATP + H2O


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Mus musculus)


name: calciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = calcidiol + H2O + 2 oxidized [adrenodoxin]


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Danio rerio)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Xenopus tropicalis)


name: HuR binds mRNAs in the nucleus (Canis familiaris)


name: Nuclear translocation of catalytic domain of Mst3 (Dictyostelium discoideum)


name: Retrograde COPI vesicles bind kinesin and microtubules (Rattus norvegicus)


name: (3S)-hydroxyoctanedioyl-CoA + NAD(+) => 3-oxooctanedioyl-CoA + H(+) + NADH


name: Addition of GlcNAc to the glycan on the A arm (Rattus norvegicus)


name: H(+) + N-carbamoyl-2-oxoglycine + NADPH => (S)-ureidoglycolate + NADP(+)


name: Elongation Of The Telomeric Chromosome End (Mus musculus)


name: (R)-glycerate + ADP-alpha-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Rattus norvegicus)


name: SPRY2 is phosphorylated by phosphorylated MNK1 (Sus scrofa)


name: IDUA hydrolyses Heparan sulfate chain(6) (Rattus norvegicus)


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Caenorhabditis elegans)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Gallus gallus)


name: Recruitment and activation of Chk1 (Homo sapiens)


name: p‑Y705-STAT3 dissociates from IL19:IL20RA:p-JAK1:IL20RB (Bos taurus)


name: (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O => (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol


name: Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = (9Z,12Z)-octadecadienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: lathosterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,8alpha-epoxy-5alpha-cholestan-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active FLT3 binds to GRAP2 (Canis familiaris)


name: Canonical WNT signaling through the atypical receptor RYK (Rattus norvegicus)


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Dictyostelium discoideum)


name: p130Cas and C3G bind PDGFR bound Crk (Bos taurus)


name: p-STAT1 dimerizes (Caenorhabditis elegans)


name: H(+) + NADPH + neopinone => NADP(+) + neopine


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Bos taurus)


name: Cleavage of the signal peptide of Preproghrelin (Canis familiaris)


name: H(+) + NADH + O2 + phthalate => cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+)


name: 3,3'-dibromobisphenol A reductive dehalogenase activity


name: PDE3A hydrolyses cAMP to AMP (Gallus gallus)


name: acetate + H(+) + oxalate => H2O + oxaloacetate


name: TP receptor can bind thromboxane (Drosophila melanogaster)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Mus musculus)


name: 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate


name: D-serine(out) + H(+)(out) <=> D-serine(in) + H(+)(in)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Homo sapiens)


name: Transfer of NEDD8 to AcM-UBE2M (Mus musculus)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Caenorhabditis elegans)


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Rattus norvegicus)


name: (24S)-hydroxycholesterol + 3'-phosphoadenylyl sulfate <=> (24S)-hydroxycholesterol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: STAB2:ligand is endocytosed (Sus scrofa)


name: 2-oxoadipate + CoA + NAD(+) <=> CO2 + glutaryl-CoA + NADH


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: ATP + glycocholate(in) + H2O => ADP + glycocholate(out) + H(+) + phosphate


name: Interaction of PAK1 with Rac1-GTP (Homo sapiens)


name: NTPDase6 hydrolyzes nucleoside diphosphates (Bos taurus)


name: AMP + ATP <=> ADP + ADP [AK2] (Saccharomyces cerevisiae)


name: Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Xenopus tropicalis)


name: ATP + holo-[peptidyl-carrier protein] + L-tryptophan => AMP + diphosphate + L-tryptophyl-[peptidyl-carrier protein]


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Homo sapiens)


name: AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide => H2O + NADH


name: Grb7 binds to the active PDGF receptor (Sus scrofa)


name: TNKS and TNKS2 PARylate PTEN (Mus musculus)


name: benzyl alcohol + cetraxate + H(+) => benzyl cetraxate + H2O


name: Defective B3GALT6 does not transfer Gal to the tetrasaccharide linker (Homo sapiens)


name: coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Caenorhabditis elegans)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Canis familiaris)


name: 15-cis-phytoene + 2 plastoquinone-9 = 9,9',15-tri-cis-zeta-carotene + 2 plastoquinol-9


name: Formation of the MLL1 complex (Bos taurus)


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)


name: H2O + N-methyl-2-oxoglutaramate = 2-oxoglutarate + methylamine


name: 4-methylsulfanyl-2-oxobutanoate + an aromatic L-alpha-amino acid => an aromatic oxo-acid + L-methionine


name: 4-epi-eremophilene + O2 + reduced [NADPH--hemoprotein reductase] = 4-epi-eremophilene-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Dictyostelium discoideum)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Xenopus tropicalis)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Bos taurus)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Xenopus tropicalis)


name: glyoxal + L-cysteinyl-[protein] = S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein]


name: DNA ligase I ligates single stranded nick in double stranded DNA (Gallus gallus)


name: acetyl-CoA + N-terminal L-methionyl-L-asparaginyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-asparaginyl-[protein]


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Sus scrofa)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Bos taurus)


name: OPLAH hydrolyses OPRO to L-Glu (Sus scrofa)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: H(+) + steviolbioside + UDP => steviolmonoside + UDP-alpha-D-glucose


name: RNA exonuclease activity, producing 3'-phosphomonoesters


name: 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP => AMP + diphosphate + H(+) + staphyloferrin B


name: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialurate + H(+)


name: H(+) + S-adenosyl-L-homocysteine + vanillate => 3,4-dihydroxybenzoate + S-adenosyl-L-methionine


name: Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B (Bos taurus)


name: Loading of antigenic peptides (Xenopus tropicalis)


name: (5-hydroxyindol-3-yl)acetaldehyde + H2O + NAD(+) = (5-hydroxyindol-3-yl)acetate + 2 H(+) + NADH


name: 2-oxoheptanedioate + acetyl-CoA + H2O => (R)-trihomocitrate + CoA + H(+)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Homo sapiens)


name: AKR1B15 reduces EST17b to E1 (Xenopus tropicalis)


name: Passive I- efflux mediated by SMCT1 (Bos taurus)


name: N-terminal L-glutaminyl-[peptide] <=> N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) = a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: type 1 metabotropic glutamate receptor binding


name: Movement of clathrin coated vesicles into early endosome (Canis familiaris)


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Danio rerio)


name: ADP + H(+) + L-lysine(in) + phosphate => ATP + H2O + L-lysine(out)


name: 5-formimidoyltetrahydrofolate + 2 H(+) <=> (6R)-5,10-methenyltetrahydrofolate + NH4(+)


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Caenorhabditis elegans)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)


name: L-type Calcium Channels close in pancreatic beta cells (Homo sapiens)


name: Translocation of WWTR1 (TAZ) to the nucleus (Xenopus tropicalis)


name: Translocation of CARMA1 to Plasma membrane (Xenopus tropicalis)


name: Uncoupled eNOS favours the formation of superoxide (Saccharomyces cerevisiae)


name: ADP + an R-cob(III)alamin(in) + H(+) + phosphate => an R-cob(III)alamin(out) + ATP + H2O


name: (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O <=> (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose


name: AH2 + 5 H(+) + 5 malonyl-CoA <=> 6-hydroxymellein + A + 5 CO2 + 5 CoA + H2O


name: Mature NOTCH heterodimer traffics to the plasma membrane (Mus musculus)


name: chloride(out) + hydrogencarbonate(in) <=> chloride(in) + hydrogencarbonate(out)


name: (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + NH4(+) = H(+) + 2 H2O + pyridinestrone carboxylate


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O <=> 8,9-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Xenopus tropicalis)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Drosophila melanogaster)


name: an N-acyl-L-homoserine lactone + H2O = a carboxylate + L-homoserine lactone


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Canis familiaris)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Danio rerio)


name: (S)-cheilanthifoline + O2 + reduced [NADPH--hemoprotein reductase] => (S)-stylopine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: a carboxylate + an aromatic L-alpha-amino acid => an N-acyl-aromatic L-alpha-amino acid + H2O


name: NADP(+) + pyridoxine => H(+) + NADPH + pyridoxal


name: ub UBXN7 is degraded by the 26S proteasome (Danio rerio)


name: RBP3 regulates atROL taken up by Muller cells (Bos taurus)


name: 1D-myo-inositol 1,4,5-trisphosphate + H2O => 1D-myo-inositol 4,5-bisphosphate + phosphate


name: HIF-alpha translocates from cytosol to nucleus (Drosophila melanogaster)


name: H2O + tuberculosinyl diphosphate = diphosphate + tuberculosinol


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Gallus gallus)


name: Canonical WNT signaling through the atypical receptor RYK (Gallus gallus)


name: PTGIS, CYP8A1 isomerise PGH2 to PGI2 (Danio rerio)


name: H(+) + NADH + O2 + theophylline = 3-methylxanthine + formaldehyde + H2O + NAD(+)


name: 2 chloride(out) + glycine betaine(out) + 3 Na(+)(out) => 2 chloride(in) + glycine betaine(in) + 3 Na(+)(in)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Saccharomyces cerevisiae)


name: fumarate(in) + L-aspartate(out) => fumarate(out) + L-aspartate(in)


name: goralatide + H2O <=> L-lysyl-L-proline + N-acetyl-L-seryl-L-aspartate


name: Thiosulfate can transfer its sulfur atom to glutathione (Canis familiaris)


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Gallus gallus)


name: glycine + glyoxylate => (3S)-3-hydroxy-D-aspartate


name: P4HB forms mixed disulphides with Hh precursors (Sus scrofa)


name: AH2 + O2 + octadecanoyl-CoA <=> (9Z)-octadecenoyl-CoA + A + 2 H2O


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Sus scrofa)


name: (3R)-1,4-thiomorpholine-3-carboxylate + NAD(+) <=> 3,4-dehydrothiomorpholine-3-carboxylate + 2 H(+) + NADH


name: Expression of POU3F1 in anterior neural plate (Homo sapiens)


name: [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + H2O <=> [CysO sulfur-carrier protein]-C-terminal Gly-Gly + H(+) + L-cysteine


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: ATP + citrate + spermidine = AMP + diphosphate + H(+) + N(8)-citryl-spermidine


name: RAB43 hydrolyses GTP (Plasmodium falciparum)


name: L-altrarate => 5-dehydro-4-deoxy-D-glucarate + H2O


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O <=> C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine


name: H(+) + NADPH + selenodiglutathione <=> glutathione + glutathioselenol + NADP(+)


name: 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA => 8 H(+) + malonamoyl-[OxyC ACP] + 8 malonyl-CoA


name: Factor Xa inhibitors bind Va:Xa (Gallus gallus)


name: Formation of tonofilament bundles (Xenopus tropicalis)


name: H2O + methylenediurea = N-(carboxyaminomethyl)urea + NH4(+)


name: PAK1 phosphorylates myosin phosphatase (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol => a 1-acyl-sn-glycero-3-phosphocholine + a triacyl-sn-glycerol


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Dictyostelium discoideum)


name: 2-hydroxyethane-1-sulfonate + FMNH2 + O2 <=> FMN + glycolaldehyde + 2 H(+) + H2O + sulfite


name: SUMOylation of TDG with SUMO2,3 (Gallus gallus)


name: 3-oxopropanoyl-CoA + H2O => 3-oxopropanoate + CoA + H(+)


name: ATP + L-tryptophan <=> diphosphate + L-tryptophyl-5'-AMP


name: RHOB binds effectors at the plasma membrane (Gallus gallus)


name: 2 H(+)(in) + L-alanyl-L-alanine(in) => 2 H(+)(out) + L-alanyl-L-alanine(out)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Danio rerio)


name: guanosine(out) + Na(+)(out) <=> guanosine(in) + Na(+)(in)


name: histone H3R8 arginine deiminase activity


name: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine => 2-methoxy-6-(all-trans-octaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Sus scrofa)


name: 3-oxooctanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyoctanoyl-[ACP] + NADP(+)


name: a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O <=> 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)


name: emodin + S-adenosyl-L-methionine => H(+) + questin + S-adenosyl-L-homocysteine


name: JAK1 phosphorylates STAT3,STAT6 (Canis familiaris)


name: Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Drosophila melanogaster)


name: Activated type I receptor phosphorylates SMAD2/3 directly (Danio rerio)


name: ATP binding to HSP90 triggers conformation change (Sus scrofa)


name: butanoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxohexanoyl-[ACP] + CO2 + holo-[ACP]


name: H(+) + L-proline betaine + NADPH + O2 = formaldehyde + H2O + N-methyl-L-proline + NADP(+)


name: 8 AMP + 8 diphosphate + 8 H(+) + PF1022F + 4 S-adenosyl-L-homocysteine => 4 (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine


name: nucleoside transmembrane transporter activity, down a concentration gradient


name: ATXN3 family cleave Ub chains (Rattus norvegicus)


name: Two FPP molecules dimerize to form presqualene diphosphate (Rattus norvegicus)


name: 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H(+) <=> 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2


name: (S)-2-succinylamino-6-oxoheptanedioate + CoA => (S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA


name: NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Xenopus tropicalis)


name: ATP + L-isoleucine + tRNA(Ile) <=> AMP + diphosphate + L-isoleucyl-tRNA(Ile)


name: Thr-180 of ULK1 is phosphorylated (Xenopus tropicalis)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Rattus norvegicus)


name: Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)


name: mycophenolic acid O-acyl-beta-D-glucuronide + UDP => mycophenolate + UDP-alpha-D-glucuronate


name: allantoate + H2O = (S)-ureidoglycolate + urea


name: 2 (S)-lactate(in) + prostaglandin D2(out) <=> 2 (S)-lactate(out) + prostaglandin D2(in)


name: a ubiquinone + 2 H(+)(in) + H2 = a ubiquinol + 2 H(+)(out)


name: tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity


name: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Sus scrofa)


name: glycyl-sarcosine(out) + H(+)(out) = glycyl-sarcosine(in) + H(+)(in)


name: SPTLC complexes transfer acyl-CoA onto serine (Mus musculus)


name: kaempferide + S-adenosyl-L-methionine = 3,4'-O-dimethylkaempferol + H(+) + S-adenosyl-L-homocysteine


name: a ribonucleotide in rRNA + S-adenosyl-L-methionine <=> a 2'-O-methylribonucleotide in rRNA + H(+) + S-adenosyl-L-homocysteine


name: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + H2O => 1D-myo-inositol 1,4,5-trisphosphate + phosphate


name: Inactive BRAF mutants:mutant RAS:GTP bind RAF1 (Homo sapiens)


name: NANP dephosphorylates Neu5Ac-9-P to Neu5Ac (Rattus norvegicus)


name: PI3K synthesizes PIP3 downstream of ALK (Rattus norvegicus)


name: 6-phospho-2-dehydro-D-gluconate + H(+) + NADH => 6-phospho-D-gluconate + NAD(+)


name: (R)-carnitine + an acyl-CoA = CoA + O-acyl-(R)-carnitine


name: (2R,3R)-dihydroquercetin + 2-oxoglutarate + O2 = CO2 + H(+) + H2O + quercetin + succinate


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)


name: H(+)(out) + L-asparagine(in) + Na(+)(in) => H(+)(in) + L-asparagine(out) + Na(+)(out)


name: Conversion of PA into DAG by PAP-1 (Bos taurus)


name: 4-cresol dehydrogenase (hydroxylating) activity


name: TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation (Gallus gallus)


name: mTORC1 phosphorylates MAF1 (Mus musculus)


name: GDP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosamine => GDP-beta-L-fucose + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine


name: (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Rattus norvegicus)


name: RAC1 and CDC42 activate PAK3 (Schizosaccharomyces pombe)


name: PP6-PPP6R3 dephosphorylates TERF2 (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + dodecanoyl-CoA => 1,2-di-(9Z)-octadecenoyl-3-dodecanoyl-sn-glycerol + CoA


name: BRCA1 binds phosphorylated RBBP8 (Gallus gallus)


name: 3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP => CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate


name: a 2'-O-methylribonucleotide in U6 snRNA + H(+) + S-adenosyl-L-homocysteine => a ribonucleotide in U6 snRNA + S-adenosyl-L-methionine


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + H2O => (9Z,12Z,15Z)-octadecatrienoate + glycerol + H(+)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Sus scrofa)


name: PP2A dephosphorylates p-RHO to RHO (Bos taurus)


name: CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Mus musculus)


name: TBX5 and KAT5 bind the SRF gene (Homo sapiens)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Dictyostelium discoideum)


name: guanosine(9) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine


name: choline(out) + n Na(+)(out) => choline(in) + n Na(+)(in)


name: ATP + L-isoleucine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate <=> ADP + dapdiamide B + H(+) + phosphate


name: Latent TGF-beta-1 binds integrins (Canis familiaris)


name: ULK1 Translocates to the mitochondria (Rattus norvegicus)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Sus scrofa)


name: 5,6,7,8-tetrahydromethanopterin + A => 7,8-dihydromethanopterin + AH2


name: ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 (Canis familiaris)


name: siderophore-iron transmembrane transporter activity


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Homo sapiens)


name: H2O + N-acetyl-4-O-acetylneuraminate => acetate + H(+) + N-acetylneuraminate


name: diiodine + 2 H2O => 2 H(+) + H2O2 + 2 iodide


name: DAG and Ca+2 bind to PKC and tether it to membrane (Saccharomyces cerevisiae)


name: 2-AG hydrolysis to arachidonate by MAGL (Rattus norvegicus)


name: ATP + daunorubicin(in) + H2O <=> ADP + daunorubicin(out) + H(+) + phosphate


name: D-glucose 6-sulfate + H2O => D-glucose + H(+) + sulfate


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Canis familiaris)


name: LAG3 (CD233) binds MHC II (Canis familiaris)


name: 26S proteasome degrades HIFalpha (Bos taurus)


name: PTPRF, PTPRS, PTPRD bind Liprins (Gallus gallus)


name: (S)-carnitine(out) + Na(+)(out) <=> (S)-carnitine(in) + Na(+)(in)


name: dimethylamine + H(+) + H2O + oxidized [electron-transfer flavoprotein] <=> formaldehyde + methylamine + reduced [electron-transfer flavoprotein]


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Drosophila melanogaster)


name: ARMS is phosphorylated by active TrkA receptor (Danio rerio)


name: LRRC16A binds F-actin capping protein (Sus scrofa)


name: 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-nonadioyl-sn-glycero-3-phosphocholine


name: 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + ATP + CoA => 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: 15-cis-4,4'-diapophytoene + 2 diphosphate => 2 (2E,6E)-farnesyl diphosphate


name: dihydroxyacetone phosphate + ubiquinol-8 => sn-glycerol 3-phosphate + ubiquinone-8


name: 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate => 16alpha,17beta-estriol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: methanol + N,N-dimethyl-4-nitrosoaniline = 4-(hydroxylamino)-N,N-dimethylaniline + formaldehyde


name: DENND5A,B exchange GTP for GDP on RAB39 (Mus musculus)


name: baicalin + UDP => baicalein + UDP-alpha-D-glucuronate


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Dictyostelium discoideum)


name: ABCC3 transports bile salts from cytosol to extracellular region (Rattus norvegicus)


name: (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate => 8,9-epoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: ARFGAPs stimulate ARF GTPase activity (Canis familiaris)


name: (R)-noradrenaline + S-adenosyl-L-methionine <=> (R)-adrenaline + H(+) + S-adenosyl-L-homocysteine


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: H(+) + o-quinone methide + peniphenone D = penilactone A


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Canis familiaris)


name: H(+)(in) + xanthosine(in) = H(+)(out) + xanthosine(out)


name: C3a receptor binds anaphylatoxin C3a (Xenopus tropicalis)


name: PANK4 hydrolyzes PPANT to pantetheine (Rattus norvegicus)


name: CCND1 recruits HDAC4 to RUNX3 (Caenorhabditis elegans)


name: Light stimulates opsin receptors (Homo sapiens)


name: (R)-dihydrolipoate + ATP + H(+) = diphosphate + N(6)-[(R)-dihydrolipoyl]-5'-AMP


name: ARL3:GTP binds the UNC119B complex (Canis familiaris)


name: HRASLS transfer acyl group from PC to PE to form NAPE (Mus musculus)


name: 2 H(+) + monuron + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3-(4-chlorophenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] <=> 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 26S proteasome degrades Ub-NFE2L2 (Danio rerio)


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Saccharomyces cerevisiae)


name: DNMT3A binds Me2sR4-HIST1H4 (Rattus norvegicus)


name: Src phosphorylate WASP,N-WASP (Gallus gallus)


name: PI is hydrolyzed to 2-acyl LPI by PLA2[13] (Sus scrofa)


name: CYP17A1 17-hydroxylates PREG (Homo sapiens)


name: CRLF1:IL27 translocates to the extracellular region (Bos taurus)


name: SMURF2 monoubiquitinates SMAD3 (Canis familiaris)


name: Fibrillin C-terminal processing (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-phosphate + H2O <=> a 2'-deoxyribonucleoside + phosphate


name: GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Bos taurus)


name: 1-acyl LPE is acylated to PE by LPEAT (Sus scrofa)


name: CLEC4A binds HIV and HCV glycoproteins (Homo sapiens)


name: a 1,2-saturated fatty acid + O2 = a (2R)-2-hydroperoxy fatty acid


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + tetradecanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-tetradecanoyl-sn-glycerol + CoA


name: 6-acetyl-D-glucose + H2O <=> acetate + D-glucose + H(+)


name: 5-carboxymethoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine => 5-hydroxyuridine(34) in tRNA + carboxy-S-adenosyl-L-methionine


name: Separation of elongating transcript from template (Gallus gallus)


name: 2 S-adenosyl-L-methionine + sarcosine <=> glycine betaine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate + orsellinate => diphosphate + ilicicolinate B


name: PLK2 phosphorylates NPM1 (Gallus gallus)


name: 2 2-oxoglutarate + 2 O2 + pentalenolactone D <=> 2 CO2 + H2O + pentalenolactone F + 2 succinate


name: chloride(out) + L-valine(out) + 2 Na(+)(out) <=> chloride(in) + L-valine(in) + 2 Na(+)(in)


name: H(+) + L-aspartate 4-semialdehyde + NADPH + putrescine => carboxyspermidine + H2O + NADP(+)


name: 3-methyl-(2E)-glutaconyl-CoA + H2O => (3S)-hydroxy-3-methylglutaryl-CoA


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => 8-hydroxycopalyl diphosphate


name: IL37(?-218):p-S423,S425-SMAD3 translocates to the nucleus (Canis familiaris)


name: cyclic pyranopterin phosphate + diphosphate => GTP


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)


name: DUOX1,2 reduce O2 to H2O2 (Saccharomyces cerevisiae)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) + H2O => 1-O-alkyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + phosphate


name: uridine(13) in tRNA <=> pseudouridine(13) in tRNA


name: inositol trisphosphate phosphatase activity


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Xenopus tropicalis)


name: beta-casomorphin-7 + H2O <=> beta-casomorphin-6 + L-isoleucine


name: gibberellin A20 + S-adenosyl-L-methionine <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Sus scrofa)


name: Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3. (Gallus gallus)


name: emodin + H(+) + H2O => emodin anthrone + O2


name: H(+) + malonyl-CoA + S-anthraniloyl-L-cysteinyl-[PqsD protein] = (2-aminobenzoyl)acetyl-CoA + CO2 + L-cysteinyl-[PqsD protein]


name: ADP + all-trans-octaprenyl phosphate + H(+) => all-trans-octaprenol + ATP


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + a di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+) => 1,2,3-tri-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose <=> [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n+1)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: CD22 binds B-cell receptor (Homo sapiens)


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Canis familiaris)


name: HuR binds the CRM1 nuclear export machinery (Mus musculus)


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Sus scrofa)


name: cAMP degradation by Phosphodiesterases (Danio rerio)


name: AMP + H(+) + hexadecanoyl-[(hydroxy)phthioceranic acid synthase] => hexadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase]


name: Arachidonic acid  is converted to 12-oxoETE by ALOX12 (Dictyostelium discoideum)


name: METAP1/2 demethylates GNAT1 (Saccharomyces cerevisiae)


name: 4-prenylphlorisobutanophenone + dimethylallyl diphosphate => deoxycohumulone + diphosphate


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Mus musculus)


name: H2O + isopenicillin N + phenylacetyl-CoA <=> CoA + H(+) + L-2-aminoadipate + penicillin G


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Sus scrofa)


name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Mus musculus)


name: CPTP transports C1P from plasma membrane to Golgi membrane (Drosophila melanogaster)


name: Cleavage of thymine by MBD4 glycosylase (Canis familiaris)


name: hederagenin + O2 + reduced [NADPH--hemoprotein reductase] = gypsogenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: ABCC3 transports bile salts from cytosol to extracellular region (Caenorhabditis elegans)


name: 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate


name: FRS2 binds to active TrkA receptor (Mus musculus)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + solavetivone => (-)-vetispiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: H(+) + NADPH + progesterone = 3beta-hydroxypregn-4-ene-20-one + NADP(+)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate => 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Danio rerio)


name: (2E)-geranyl diphosphate + H2O = diphosphate + sabinene hydrate


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Rattus norvegicus)


name: Synthesis of dolichyl-phosphate-glucose (Danio rerio)


name: keto-D-fructose 6-phosphate + phosphate <=> acetyl phosphate + D-erythrose 4-phosphate + H2O


name: PA is hydrolyzed to 1-acyl LPA by PLA2[15] (Caenorhabditis elegans)


name: 2 Fe(III)-[cytochrome c553] + formate <=> CO2 + 2 Fe(II)-[cytochrome c553] + H(+)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Caenorhabditis elegans)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Saccharomyces cerevisiae)


name: GAMT gene expression is stimulated by MECP2 (Homo sapiens)


name: cortisone + H(+) + NADPH => 4,5beta-dihydrocortisone + NADP(+)


name: NOTCH3 gene transcription (Homo sapiens)


name: dihydrochanoclavine-I aldehyde => 6,8-dimethyl-6,7-didehydroergoline + H2O


name: RFC dissociates after sliding clamp formation (Gallus gallus)


name: GGA3 associates with activated MET receptor (Homo sapiens)


name: Prokineticin receptors bind prokineticin (Mus musculus)


name: N(4)-aminopropylspermidine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + N(4)-bis(aminopropyl)spermidine + S-methyl-5'-thioadenosine


name: (S)-cystathionine ketimine + 2 H(+) + NADH => (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NAD(+)


name: Elongating transcript encounters a lesion in the template (Canis familiaris)


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: beta-alanine + H(+) + NADH + pyruvate => (R)-beta-alanopine + H2O + NAD(+)


name: quercitrin + UDP-beta-L-rhamnose => H(+) + quercetin 3,7-bis-O-alpha-L-rhamnoside + UDP


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Bos taurus)


name: (22S)-22-hydroxycampest-4-en-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (22S)-22-hydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Canis familiaris)


name: (-)-secoisolariciresinol + NADP(+) <=> (+)-lariciresinol + H(+) + NADPH


name: acarbose + ATP => acarbose 7(IV)-phosphate + ADP + H(+)


name: H2O + trans-2,3-epoxysuccinate = (2R,3S)-tartrate


name: di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP => di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine


name: TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Danio rerio)


name: TCF/LEF:CTNNB1 bind the AXIN2 gene (Homo sapiens)


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Xenopus tropicalis)


name: L-pipecolate + O2 => H(+) + H2O2 + L-1-piperideine-6-carboxylate


name: thiamine diphosphate(out) <=> thiamine diphosphate(in)


name: 10,11-epoxy-(7Z,13Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA (Sus scrofa)


name: Transfer of ISG15 from E1 to E2 (UBCH8) (Mus musculus)


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Schizosaccharomyces pombe)


name: H2O + substance P => L-Leu-L-Met-NH2 + substance P(1-9)


name: An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Sus scrofa)


name: 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one = 3-isopropenyl-6-oxoheptanoate + H(+)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Caenorhabditis elegans)


name: H2O + L-alanin-3-yl L-histidin-5-yl sulfoxide => L-cysteine + L-histidine + O2


name: Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)


name: a 2'-unsubstituted isoflavone + O2 + reduced [NADPH--hemoprotein reductase] <=> a 2'-hydroxyisoflavone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-hydroxycyclohexan-1-one + H(+) + NADH + NH4(+) => 2-aminocyclohexanol + H2O + NAD(+)


name: GTP + NAD(+) <=> H(+) + N(2)-(ADP-D-ribosyl)-GTP + nicotinamide


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 = (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate


name: RUNX3 binds SMAD3 and SMAD4 (Sus scrofa)


name: The Ligand:GPCR:Gq complex dissociates (Mus musculus)


name: indole-3-pyruvate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tryptophan


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Drosophila melanogaster)


name: MECP2 mutants P302R,K304E,K305R,R306C,(R306H) do not bind NCoR/SMRT complex (Homo sapiens)


name: 3-[(R)-glyceryl]-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + H(+) + oxidized 3PG-factor420-0


name: losartan-2-N-beta-D-glucuronide + UDP => losartan + UDP-alpha-D-glucuronate


name: Synthesis of full-length duplex viral DNA with a discontinuous plus strand (Homo sapiens)


name: Defective DCXR does not reduce L-xylulose to xylitol (Homo sapiens)


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate <=> 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H(+) + UDP


name: NUMB:ITCH binds GLI1 (Xenopus tropicalis)


name: transmembrane signaling receptor activity


name: Sphingomyelinase is activated by the NGF:p75NTR complex (Homo sapiens)


name: ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Bos taurus)


name: ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA (Danio rerio)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Sus scrofa)


name: Association of beta-catenin with the destruction complex (Homo sapiens)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Danio rerio)


name: ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA (Mus musculus)


name: decan-1-ol + hexadecanoyl-CoA => CoA + decanyl hexadecanoate


name: cholest-5-en-3-one + H2O2 => cholesterol + O2


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Sus scrofa)


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Gallus gallus)


name: Na(+)(in) + uracil(in) => Na(+)(out) + uracil(out)


name: D-5-[2-(methylsulfanyl)ethyl]hydantoin + H2O = H(+) + N-carbamoyl-D-methionine


name: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH <=> benzene-1,2,4-triol + NAD(+)


name: a dicarboxylate(in) + urate(out) => a dicarboxylate(out) + urate(in)


name: 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminopentanoate => 2-oxopentanoate + N(omega),N(omega)-dimethyl-L-arginine


name: kaempferol 3-O-beta-D-glucoside + malonyl-CoA => CoA + kaempferol 3-O-(6-O-malonyl-beta-D-glucoside)


name: H2O + xanthosine <=> D-ribose + xanthine


name: 2-acyl LPC is acylated to PC by LPCAT (Sus scrofa)


name: Transcriptional activation of FAS monomer gene by ChREBP:MLX (Dictyostelium discoideum)


name: AMP + diphosphate + heptanal + NADP(+) => ATP + H(+) + heptanoate + NADPH


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Plasmodium falciparum)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Schizosaccharomyces pombe)


name: L-arginine(in) + L-methionine(out) + Na(+)(out) <=> L-arginine(out) + L-methionine(in) + Na(+)(in)


name: SLC26A4 transports I- from cytosol to extracellular region (Homo sapiens)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Gallus gallus)


name: (R)-lactate + 2-oxoglutarate => (R)-2-hydroxyglutarate + pyruvate


name: Cohesin binds PDS5 and WAPAL (Homo sapiens)


name: 5-hydroxykynurenamine + CO2 => 5-hydroxy-L-kynurenine + H(+)


name: Adhesion of integrin alphaIIbbeta3 to fibrin network (Sus scrofa)


name: 2-methylpropanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] <=> CoA + N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein]


name: 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> cholesta-5,7-dien-3beta,24S-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an aromatic aldehyde + hydrogen cyanide => an aromatic (S)-hydroxynitrile


name: TDG excises 5-carboxylcytosine (Danio rerio)


name: 2-oxoglutarate + decanoyl-CoA + O2 = 2-hydroxydecanoyl-CoA + CO2 + succinate


name: HTR3A antagonists bind HTR3A pentamer (Canis familiaris)


name: GBF1 stimulates nucleotide exchange on ARF (Canis familiaris)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+) = 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH


name: 2-all-trans-octaprenylphenol + H(+) + NADPH + O2 = 3-(all-trans-octaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: Y693-STAT4 dimer translocates to the nucleus (Drosophila melanogaster)


name: p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Gallus gallus)


name: 5-dehydroepisterol + H(+) + S-adenosyl-L-homocysteine => 7-dehydrodesmosterol + S-adenosyl-L-methionine


name: An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Homo sapiens)


name: L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate (Homo sapiens)


name: ATP + L-glutamate + L-glutamyl-[protein] => ADP + gamma-L-glutamyl-L-glutamyl-[protein] + H(+) + phosphate


name: PIP3 binds to RhoA and activates it (Bos taurus)


name: 2 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 O2 = 2 CO2 + 2 formaldehyde + L-arginyl-[protein] + 2 succinate


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Schizosaccharomyces pombe)


name: CoA + propanoyl phosphate => phosphate + propanoyl-CoA


name: Cdc45 associates with the pre-replicative complex at the origin (Bos taurus)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Canis familiaris)


name: ATP + gamma-L-glutamyl-(2S)-2-aminobutanoate + glycine => ADP + H(+) + ophthalmate + phosphate


name: ADP + alpha-D-glucose 6-phosphate + H(+) => alpha-D-glucose + ATP


name: NIK autophosphorylates on T559 (Xenopus tropicalis)


name: beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP-alpha-D-galactofuranose => [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 H(+) + 28 UDP


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Homo sapiens)


name: desmethyl-dehydrogriseofulvin + 2 H2O + oxidized [NADPH--hemoprotein reductase] => griseophenone B + H(+) + O2 + reduced [NADPH--hemoprotein reductase]


name: oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: PDE4A hydrolyses cAMP to AMP (Caenorhabditis elegans)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Mus musculus)


name: PDPK1 phosphorylates PKN1,2,3 (Caenorhabditis elegans)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Bos taurus)


name: Dissociation of paradoxically activated RAS:BRAF complexes (Homo sapiens)


name: N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2


name: 4-hydroxybenzaldehyde + 4 H(+) + 4 reduced [azurin] => 4-methylphenol + H2O + 4 oxidized [azurin]


name: HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (Mus musculus)


name: (2S)-2-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Mus musculus)


name: 2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2'-hydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Caspase-mediated cleavage of claspin (Mus musculus)


name: (S)-scoulerine + S-adenosyl-L-methionine => (S)-tetrahydrocolumbamine + H(+) + S-adenosyl-L-homocysteine


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Homo sapiens)


name: Gamma-secretase cleaves APP(672-770) to APP(672-711) and APP(672-713) (Homo sapiens)


name: ATP + beta-citrylglutamate(in) + H2O = ADP + beta-citrylglutamate(out) + H(+) + phosphate


name: 12-phosphooxy-(9Z)-octadecenoate + H2O <=> 12-hydroxy-(9Z)-octadecenoate + phosphate


name: all-trans-zeaxanthin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: AH2 + L-cysteine + Mo-molybdopterin => A + H2O + L-alanine + thio-Mo-molybdopterin


name: L-histidine(out) + L-tryptophan(in) <=> L-histidine(in) + L-tryptophan(out)


name: Recruitment of PLC-gamma1 to SLP-76 (Canis familiaris)


name: a 1-acyl-sn-glycero-3-phosphate + ethanolamine + H(+) => a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O


name: PTPN7 dephosphorylates p-T,Y-MAPKs (Bos taurus)


name: ATP + Ca(2+)(in) + H2O <=> ADP + Ca(2+)(out) + H(+) + phosphate


name: (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H2O <=> (E)-1-(glycyl-L-cystein-S-yl)-2-(1H-indol-3-yl)acetohydroximate + L-glutamate


name: (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] => (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: (2E,6E)-farnesyl diphosphate + H(+) + NADPH + O2 => (2E,6E)-omega-hydroxy-farnesyl diphosphate + H2O + NADP(+)


name: GDIs block activation of RHOA (Schizosaccharomyces pombe)


name: 11-O-acetylcyathatriol + UDP-alpha-D-glucose <=> erinacine Q2 + H(+) + UDP


name: H2O + L-cysteine + O2 <=> 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)


name: Insulin receptor de-phosphorylation (Xenopus tropicalis)


name: FMNH2 + methanesulfonate + O2 = FMN + formaldehyde + 2 H(+) + H2O + sulfite


name: NNMT transfers CH3 from AdoMet to PY (Homo sapiens)


name: ADP-alpha-D-glucose + D-glucose 6-phosphate => ADP + alpha,alpha-trehalose 6-phosphate + H(+)


name: Binding of TFIIIC to Type 2 promoter (Xenopus tropicalis)


name: O2 + prostaglandin A1 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy prostaglandin A1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-(prostaglandin E2)-sn-glycero-3-phosphocholine + H2O => H(+) + prostaglandin E2 + sn-glycerol 3-phosphocholine


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Caenorhabditis elegans)


name: A + H2O + quinaldate => AH2 + kynurenate


name: a globoside GalGb4Cer + CMP-N-acetyl-beta-neuraminate => a globoside MSGG + CMP + H(+)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Danio rerio)


name: S-3-(hexan-1-ol)-L-cysteine = 2-aminoprop-2-enoate + 3-sulfanyl-1-hexanol


name: 5-amino-6-(5-phospho-D-ribosylamino)uracil + H2O => 5,6-diaminouracil + D-ribose 5-phosphate


name: ATP + D-glucosamine = ADP + D-glucosamine 6-phosphate + H(+)


name: 1-acyl LPC is acylated to PC by LPCAT (Caenorhabditis elegans)


name: ADP + D-erythrulose 4-phosphate + H(+) => ATP + D-erythrulose


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Rattus norvegicus)


name: Caspase mediated cleavage of beta-catenin (Mus musculus)


name: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate


name: Active NIK phosphorylates IKKA dimer (Canis familiaris)


name: HV1-mediated H+ transfer (Gallus gallus)


name: Caspase-mediated cleavage of gelsolin (Gallus gallus)


name: chylomicron remnant + apoE => chylomicron remnant:apoE complex (Mus musculus)


name: 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Canis familiaris)


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Canis familiaris)


name: H(+)(in) + N,N-dimethylglycine(in) = H(+)(out) + N,N-dimethylglycine(out)


name: Proteasome mediated degradation of COP1 (Rattus norvegicus)


name: RAB13 GEFs exchange GTP for GDP on RAB13 (Caenorhabditis elegans)


name: LIPT2 transfers octanoyl group to GCSH (Schizosaccharomyces pombe)


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Mus musculus)


name: Cis-Heterodimerization of nephrin and KIRREL (Danio rerio)


name: Interaction of integrin alphaVbeta3 with Fibrillin (Canis familiaris)


name: 2-oxobutanoate + L-methionine <=> (2S)-2-aminobutanoate + 4-methylsulfanyl-2-oxobutanoate


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Mus musculus)


name: PCSK9:LDLR bind to Clathrin (Xenopus tropicalis)


name: CHSY1 transfers GalNAc to chondroitin (Rattus norvegicus)


name: ADP + H(+) + N-11-cis-retinylidenephosphatidylethanolamine(in) + phosphate => ATP + H2O + N-11-cis-retinylidenephosphatidylethanolamine(out)


name: (S)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2


name: formyl-CoA + heptadecanal => (2R)-2-hydroxyoctadecanoyl-CoA


name: 3',2'-cGAMP + diphosphate => pppA(2'-5')pG


name: prephenate + S-adenosyl-L-methionine = 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O


name: omega-hydroxy fatty acyl-CoA synthetase activity


name: PDE4A,C,D hydrolyse cAMP (Drosophila melanogaster)


name: streptothricin F acid => H2O + streptothricin F


name: KIBRA (WWC1) binds LATS proteins (Rattus norvegicus)


name: MET bound PI3K generates PIP3 (Gallus gallus)


name: a 2-oxocarboxylate + H(+) <=> an aldehyde + CO2


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA


name: SLC26A4 does not transport I- from cytosol to extracellular region (Homo sapiens)


name: H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine = H(+) + N-acyl-15-methylhexadecasphing-4-enine + phosphocholine


name: FOXO1,FOXO3 and SMAD3 bind TRIM63 gene promoter (Homo sapiens)


name: KCNH2:KCNE transport K+ from cytosol to extracellular region (Gallus gallus)


name: H2O + sinigrin <=> (Z)-N-(sulfonatooxy)prop-2-enimidothioate + D-glucose + H(+)


name: Cho is phosphorylated to PCho by CHK dimer (Canis familiaris)


name: D-arabinose + NADP(+) <=> D-arabinono-1,4-lactone + H(+) + NADPH


name: ATP(in) + UDP(out) <=> ATP(out) + UDP(in)


name: 2-oxoglutarate + fumigatonoid C + O2 => CO2 + H2O + novofumigatonin + succinate


name: 6-O-guanylylstreptomycin + diphosphate => GTP + streptomycin


name: cAMP induces dissociation of inactive PKA tetramers (Canis familiaris)


name: Fusion of late-endosome derived vesicles at the TGN (Bos taurus)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Rattus norvegicus)


name: L-glutamate(in) + N-acetyl-L-cysteine(out) => L-glutamate(out) + N-acetyl-L-cysteine(in)


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Homo sapiens)


name: Expression of Ras-related protein Ral-A (Homo sapiens)


name: acetyl-CoA + N-acetylneuraminate <=> CoA + N-acetyl-7-O-acetylneuraminate


name: Dissociation of the P2Y purinoceptor 1:Gq complex (Homo sapiens)


name: PGH2 is reduced to PGF2a by FAM213B (Homo sapiens)


name: ABCC1 transports cytosolic RCbl to extracellular region (Dictyostelium discoideum)


name: ABCA12 transports lipids from cytosol to extracellular region (Homo sapiens)


name: COPII coat binds TRAPPCII and RAB1:GDP (Plasmodium falciparum)


name: dimethylallyl diphosphate + isopentenyl diphosphate <=> (2E)-geranyl diphosphate + diphosphate


name: PTEN mRNA translation is negatively regulated by microRNAs (Homo sapiens)


name: Factor D cleaves C3b-bound Factor B (Bos taurus)


name: Fibrillin C-terminal processing (Sus scrofa)


name: gibberellin A25,oxoglutarate:oxygen oxidoreductase activity


name: Activation of ATP sensitive Potassium channels in muscle cells (Drosophila melanogaster)


name: chlorophyll a + 2 H(+) => Mg(2+) + pheophytin a


name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Canis familiaris)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Canis familiaris)


name: 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + ATP + L-cysteine <=> 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + H(+)


name: 7-deoxyloganetate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => (+)-cis-trans-nepetalactol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: Phosphorylated STATs are released (Sus scrofa)


name: (8R)-8-hydroxynonanoyl-CoA + O2 => (2E,8R)-8-hydroxynonenoyl-CoA + H2O2


name: FAD + H(+) + 2 H2O + ilicicolin A => chloride + FADH2 + ilicicolin B + O2


name: FAM83B, (FAM83A, FAM83D) bind EGFR (Xenopus tropicalis)


name: an inositol-1-phosphoceramide + H2O => 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)


name: 3-sulfanylpropanoate + O2 = 3-sulfinopropanoate + H(+)


name: AMP + diphosphate + H(+) + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] => ATP + L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphate


name: PC catalyzes the carboxylation of PYR to form OA (Danio rerio)


name: TPCN1/2 transport lysosomal Ca2+ to cytosol  (Xenopus tropicalis)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Mus musculus)


name: Ubiquitinated AXIN is degraded by the proteasome (Sus scrofa)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Plasmodium falciparum)


name: Interleukin-3 receptor alpha subunit binds Interleukin-3 (Rattus norvegicus)


name: RHOA:GTP binds RHPN1 or RHPN2 (Mus musculus)


name: ADP + coproporphyrin III(out) + H(+) + phosphate => ATP + coproporphyrin III(in) + H2O


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol <=> a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: 2-oxoglutarate + a 1,N(6)-etheno-2'-deoxyadenosine in single-stranded DNA + H2O + O2 => a 2'-deoxyadenosine in single-stranded DNA + CO2 + glyoxal + succinate


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Gallus gallus)


name: Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Rattus norvegicus)


name: TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (Mus musculus)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Xenopus tropicalis)


name: an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] => a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: 4-methylpentanoate + ATP + CoA => 4-methylpentanoyl-CoA + AMP + diphosphate


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)


name: Phosphorylation of SLP-76 by p-SYK (Sus scrofa)


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Homo sapiens)


name: trans-Golgi Network Coat Assembly (Rattus norvegicus)


name: 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2 = 3'-N-debenzoyltaxol + A + H2O


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Xenopus tropicalis)


name: 3,4-dihydroxybenzoate + UDP-alpha-D-glucose = 1-O-(3,4-dihydroxy-benzoyl)-beta-D-glucose + UDP


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Mus musculus)


name: 5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine <=> [LarE protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: (3R)-hydroxytetradecanoyl-[ACP] => (2E)-tetradecenoyl-[ACP] + H2O


name: PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release (Homo sapiens)


name: 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: TFAP2C translocates to the nucleus (Danio rerio)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O <=> (11R,12R)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: H2O + L,L-cystathionine = 2-oxobutanoate + L-cysteine + NH4(+)


name: S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out) => S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in)


name: NAT1,2 acetylate APAP-Cys to APAP-Mer (Homo sapiens)


name: (2E)-octenoyl-[ACP] + H(+) + NADH = NAD(+) + octanoyl-[ACP]


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Bos taurus)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: TRIM33 monoubiquitinates SMAD4 (Sus scrofa)


name: AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it (Sus scrofa)


name: (3R)-hydroxytetradecanoyl-[ACP] + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine => H(+) + holo-[ACP] + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine


name: H2O + phlorizin <=> beta-D-glucose + phloretin


name: nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs (Homo sapiens)


name: 19-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin] => 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Dictyostelium discoideum)


name: Formation of allysine by LOX (Canis familiaris)


name: L-Glutamine transport into neurons (Canis familiaris)


name: PRDX1 overoxidizes (Schizosaccharomyces pombe)


name: Activation of claspin (Rattus norvegicus)


name: CoA + H(+) + N-hexacosanoyl-eicosan-(4R)-hydroxysphinganine => (4R)-hydroxyeicosasphinganine + hexacosanoyl-CoA


name: CoA + H(+) + N-tetracosanoyl-taurine => taurine + tetracosanoyl-CoA


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Homo sapiens)


name: acetyl-CoA + 8 H(+) + holo-[ACP] + 8 malonyl-CoA <=> 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + 8 CO2 + 9 CoA + 2 H2O


name: SUMOylation of TFAP2C with SUMO1 (Caenorhabditis elegans)


name: Trans-autophosphorylation of ERBB2 heterodimers (Mus musculus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Plasmodium falciparum)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Bos taurus)


name: AFG3L2:SPG7 binds SMDT1 (EMRE) (Canis familiaris)


name: Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Xenopus tropicalis)


name: LIPC dimer hydrolyses TAG to DAG and FA (Drosophila melanogaster)


name: Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65) (Homo sapiens)


name: Membrane-anchored TNF-α binds TNFR1 (Homo sapiens)


name: Recruitment of TBK1/IKK epsilon to K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR4 followed by their activation (Canis familiaris)


name: 16-hydroxyhexadecanoate + NAD(+) => 16-oxohexadecanoate + H(+) + NADH


name: KCTD1 binds TFAP2 homo- and heterodimers (Gallus gallus)


name: 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-octadecanoylglycerol + H(+)


name: S-nitrosylation of cysteine residues in proteins by N2O3 (Homo sapiens)


name: D-alanine(in) + L-alanine(out) => D-alanine(out) + L-alanine(in)


name: Interleukin-27 translocates from the ER lumen to the extracellular region (Sus scrofa)


name: NDUF subunits bind to form the FP subcomplex (Homo sapiens)


name: SCF(SKP2) complex binds RUNX2 (Drosophila melanogaster)


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Danio rerio)


name: Recruitment Of Cytoplasmic Proteins To Vesicles (Gallus gallus)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Plasmodium falciparum)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate


name: PIAS1 SUMOylates SATB1 with SUMO2,3 (Sus scrofa)


name: eicosanoate + glycine = H2O + N-eicosanoylglycinate


name: 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => 3 O2 + obtusifoliol + 3 reduced [NADPH--hemoprotein reductase]


name: PGE2 is converted to PGF2a by CBR1 (Danio rerio)


name: 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA => 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA


name: RANBP2 SUMOylates MDM2 with SUMO1 (Bos taurus)


name: butan-2-one + NADP(+) => but-3-en-2-one + H(+) + NADPH


name: RHOG GAPs stimulate RHOG GTPase activity (Homo sapiens)


name: Metabotropic glutamate receptors bind glutamate (Xenopus tropicalis)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O = (9Z,12Z)-octadecadienoate + 2,3-di-(9Z,12Z)-octadecadienoyl-sn-glycerol + H(+)


name: Association of procollagen type XX (Caenorhabditis elegans)


name: MKL1 translocates from cytosol to the nucleus (Gallus gallus)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Xenopus tropicalis)


name: an N-(acyl)-sphingosylphosphocholine <=> an N-(acyl)-sphingosyl-1,3-cyclic phosphate + choline


name: SFTPD binds with itself to form SFTPD 12mer (Rattus norvegicus)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Bos taurus)


name: cis-3,4-dehydroadipyl-CoA + 2 H(+) + NADPH => (3Z)-6-oxohex-3-enoyl-CoA + H2O + NADP(+)


name: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Homo sapiens)


name: Translocation of YAP1 to the nucleus (Bos taurus)


name: dehydroepiandrosterone 3-sulfate(out) + glutarate(in) = dehydroepiandrosterone 3-sulfate(in) + glutarate(out)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Sus scrofa)


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Rattus norvegicus)


name: AMOT proteins bind WWTR1 (TAZ) (Rattus norvegicus)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Danio rerio)


name: (2R)-3-phosphoglycerate + an NDP-alpha-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + a ribonucleoside 5'-diphosphate + H(+)


name: AMP + H(+) + octanoyl-[ACP] => holo-[ACP] + octanoyl-AMP


name: 5-taurinomethyluridine(34) in tRNA + AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] = 5-taurinomethyl-2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]


name: Trimerization of cytosolic HSF1 (Homo sapiens)


name: Conjugation of SUMO1 to UBA2:SAE1 (Danio rerio)


name: EGFR binds EGF ligand (Rattus norvegicus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: USP13 and OTUD3 deubiquitinate PTEN (Drosophila melanogaster)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b (d18:1(4E)) + CMP + H(+)


name: ATP + eicosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] <=> AMP + diphosphate + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Drosophila melanogaster)


name: IL21 receptor STAT binding (Danio rerio)


name: WLS binds WNT ligands in the Golgi (Homo sapiens)


name: ACER3 hydrolyzes phytoceramide (Sus scrofa)


name: H2O + N(5)-acyl-L-ornithine ester <=> an alcohol + H(+) + N(5)-acyl-L-ornithine


name: HSPG2 (perlecan) degradation by MMP14, MMP15 (Drosophila melanogaster)


name: FABP5:atRA translocates from cytosol to nucleoplasm (Mus musculus)


name: PP2A dephosphorylates p-RHO to RHO (Mus musculus)


name: CYP3A4, CYP2B6 bind ritonavir (Bos taurus)


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Rattus norvegicus)


name: atROL binds RBP1 to form RBP1:atROL (Drosophila melanogaster)


name: H2O + pravastatin lactone => H(+) + pravastatin


name: Estrogen-responsive TFF1 gene expression (Homo sapiens)


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Xenopus tropicalis)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Rattus norvegicus)


name: GDP + S-adenosyl-L-methionine <=> N(7)-methyl-GDP + S-adenosyl-L-homocysteine


name: beta-D-glucosyl crocetin + UDP-alpha-D-glucose = bis(beta-D-glucosyl) crocetin + UDP


name: AH2 + GTP + S-adenosyl-L-methionine <=> (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Saccharomyces cerevisiae)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Xenopus tropicalis)


name: rDNA spacer replication fork barrier binding


name: Heterodimerization of CEACAMs (Homo sapiens)


name: a ribonucleoside 5'-triphosphate + RNA(n) <=> diphosphate + RNA(n+1)


name: AKT phosphorylates p21Cip1 and p27Kip1 (Caenorhabditis elegans)


name: 3-hydroxypyruvate + H2O2 + NH4(+) => H2O + L-serine + O2


name: gamma-L-glutamyl-butirosin B <=> 5-oxo-L-proline + butirosin B


name: SUMOylation of BLM with SUMO2,3 (Plasmodium falciparum)


name: H2O + NAD(+) + phosphonoacetaldehyde = 2 H(+) + NADH + phosphonoacetate


name: N,N',N''-triacetylchitotriose + O2 <=> H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone


name: AKT-phosphorylated FOXO3 translocates to cytosol (Mus musculus)


name: Cleaved KMT2A dimers translocate to the nucleus (Homo sapiens)


name: H2O + NADP(+) + nitrosobenzene <=> H(+) + NADPH + nitrobenzene


name: 5-dehydro-D-gluconate + NADP(+) <=> 2,5-didehydro-D-gluconate + H(+) + NADPH


name: ATP + H2O + Pb(2+)(in) <=> ADP + H(+) + Pb(2+)(out) + phosphate


name: N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate (Drosophila melanogaster)


name: CDK5 phosphorylates DARPP-32 on Thr75 (Bos taurus)


name: 2 3-(4-hydroxyphenyl)pyruvate + H(+) = atromentin + 2 H2O


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Sus scrofa)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose (Bos taurus)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O = acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative


name: H2O + prostaglandin D2-1-glycerol ester = glycerol + H(+) + prostaglandin D2


name: ABP1 binds SHANK proteins (Caenorhabditis elegans)


name: L-erythrulose 1-phosphate = D-erythrulose 4-phosphate


name: n H(+)(in) + serotonin(out) => n H(+)(out) + serotonin(in)


name: cis,cis-muconate + 2 H(+) => catechol + O2


name: CYP26A1,B1,C1 4-hydroxylate atRA (Homo sapiens)


name: dTDP-alpha-D-fucose + NAD(+) <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADH


name: AH2 + archaetidylglycerol + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + macrocyclic archaetidylglycerol


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Sus scrofa)


name: PSD-95 binds NMDA receptor (Canis familiaris)


name: 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol + 2 Fe(III)-[cytochrome b5] + H2O


name: protein-disulfide reductase (NAD(P)) activity


name: Collagen type XXV ectomain shedding (Canis familiaris)


name: Reduction of desmosterol to cholesterol (Canis familiaris)


name: c-src associates with Cx43 in gap junctions (Homo sapiens)


name: HCNs:cAMP bind SNIs (Drosophila melanogaster)


name: AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Rattus norvegicus)


name: 3-phenylpropanal + hydrogen cyanide => (2S)-2-hydroxy-4-phenylbutanenitrile


name: C3G stimulates nucleotide exchange on Rap1 (Canis familiaris)


name: GAB1 recruits CRK,CRKL to MET (Gallus gallus)


name: RNA polymerase II-specific DNA-binding transcription factor binding


name: (S)-ureidoglycolate + NH4(+) => (S)-2-ureidoglycine + H2O


name: isoorientin + O2 <=> 3'-dehydroisoorientin + H2O2


name: SAMD8 transfers phosphatidyl from PE onto C16DH CER (Homo sapiens)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Dictyostelium discoideum)


name: ATP + NH4(+) = ADP + 2 H(+) + phosphoramidate


name: GBF1 stimulates ARF nucleotide exchange (Drosophila melanogaster)


name: a N-(2-hydroxyacyl)sphing-4-enine + UDP-alpha-D-galactose = H(+) + N-(2-hydroxyacyl)-beta-D-galactosyl-sphing-4-enine + UDP


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Xenopus tropicalis)


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Rattus norvegicus)


name: 3beta,16alpha-dihydroxy-androst-5-en-17-one + acetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 16alpha,17alpha-dihydroxypregnenolone + O2 + reduced [NADPH--hemoprotein reductase]


name: Binding of ADAR2 homodimer to dsRNA duplex (Bos taurus)


name: Na(+)(in) + O-acyl-(R)-carnitine(in) => Na(+)(out) + O-acyl-(R)-carnitine(out)


name: Retromer associates with WLS (Bos taurus)


name: PEX19 binds class I peroxisomal membrane proteins (Gallus gallus)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Drosophila melanogaster)


name: Formation of stem-loop structure in ApoB mRNA (Homo sapiens)


name: Glypican-1 (GPC1) binds SLIT2 (Mus musculus)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Gallus gallus)


name: NSF and SNAPs bind cis-SNARE complex (Rattus norvegicus)


name: Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Danio rerio)


name: SHC1 phosphorylation by ERBB2 heterodimers (Sus scrofa)


name: Myoglobin binds oxygen (Rattus norvegicus)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine <=> 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP (Canis familiaris)


name: 2-oxoglutarate + 3,5-diiodo-L-tyrosine => 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate


name: (9S)-hydroperoxy-(10E,12Z)-octadecadienoate + 2 glutathione => (9S)-hydroxy-(10E,12Z)-octadecadienoate + glutathione disulfide + H2O


name: (E)-2-methylpropanal oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-2-methylpropanenitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Canis familiaris)


name: H(+) + NADPH + prostaglandin E1 <=> NADP(+) + prostaglandin F1


name: DAG and Ca+2 bind to PKC and tether it to membrane (Xenopus tropicalis)


name: Release of SEPT4 from mitochondria (Danio rerio)


name: (2R,9S)-annullatin H + A <=> (2R)-annullatin F + AH2


name: heptan-1-ol + NADP(+) <=> H(+) + heptanal + NADPH


name: androsterone + H(+) + NADPH <=> 5alpha-androstane-3alpha,17beta-diol + NADP(+)


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Homo sapiens)


name: HILPDA binds lipid droplets (Sus scrofa)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Xenopus tropicalis)


name: (4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O => 3-oxoadipate + H(+)


name: CIDEA:CIDEC binds lipid droplets (Bos taurus)


name: NEIL3 cleaves 5-guanidinohydantoin (Bos taurus)


name: holo-[cytochrome c] = apo-[cytochrome c] + heme b


name: alpha-maltose 6'-phosphate + H2O => D-glucose + D-glucose 6-phosphate


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Caenorhabditis elegans)


name: chrodrimanin E + H2O + NADP(+) => H(+) + NADPH + O2 + verruculide A


name: (1R,2S,4S)-neoisodihydrocarveol + NAD(+) = (1R,4S)-isodihydrocarvone + H(+) + NADH


name: NFE2L2 translocates from cytosol to nucleoplasm (Sus scrofa)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Dictyostelium discoideum)