name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + dodecanoyl-[ACP] => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + holo-[ACP]


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Mus musculus)


name: 2-oxoglutarate + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose = dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + L-glutamate


name: (-)-vetispiradiene + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + solavetivol


name: Mitochondrial FPGS-1 transforms THF to THFPG (Xenopus tropicalis)


name: H2O + O2 + sarcosine => glyoxylate + H2O2 + methylamine


name: CPO transforms COPRO3 to PPGEN9 (Danio rerio)


name: ATP + H2O + leukotriene C4(in) = ADP + H(+) + leukotriene C4(out) + phosphate


name: type 2 proteinase activated receptor binding


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Homo sapiens)


name: Lamellar bodies bind the early cornified envelope (Rattus norvegicus)


name: NPHP4 protein binds LATS proteins (Gallus gallus)


name: Na+/H+ exchanger transport (at cell membrane) (Saccharomyces cerevisiae)


name: acetate + an S-substituted L-cysteine => an N-acetyl-L-cysteine-S-conjugate + H2O


name: (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O = (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA


name: (E)-cinnamate + H(+) + H2O2 => (E)-cinnamaldehyde + H2O + O2


name: H2O + NAD(+) + propanal <=> 2 H(+) + NADH + propanoate


name: (3R)-3-hydroxybutanoyl-CoA + H2O => (R)-3-hydroxybutanoate + CoA + H(+)


name: festuclavine + NAD(+) <=> 6,8-dimethyl-6,7-didehydroergoline + H(+) + NADH


name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 (Mus musculus)


name: glyoxylate + H2O + O2 => H(+) + H2O2 + oxalate


name: TOPORS SUMOylates SIN3A with SUMO1 (Rattus norvegicus)


name: 7-hydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => 7,8-dihydroxyflavone + S-adenosyl-L-methionine


name: ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine => ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate


name: sodium:inorganic phosphate symporter activity


name: 3 Fe(III)-[cytochrome c] + hydroxylamine = 3 Fe(II)-[cytochrome c] + 3 H(+) + nitric oxide


name: RHOF binds effectors at the plasma membrane (Canis familiaris)


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Mus musculus)


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Dictyostelium discoideum)


name: ERBB2 T798M does not bind afatinib (Homo sapiens)


name: LEAP2 binds bacteria (Rattus norvegicus)


name: Formation of Cyclin A:Cdc2 complexes (Drosophila melanogaster)


name: ATP + H2O + thiosulfate(out) <=> ADP + H(+) + phosphate + thiosulfate(in)


name: Migfilin interacts with VASP (Canis familiaris)


name: ATP + glycyl-[methyl-coenzyme M reductase] + hydrogen sulfide <=> ADP + phosphate + thioglycyl-[methyl-coenzyme M reductase]


name: levan fructotransferase (DFA-IV-forming) activity


name: AMP + diphosphate + H(+) + L-tyrosyl-L-arginine => ATP + L-arginine + L-tyrosine


name: Serum albumin binds 2-lysophosphatidylcholine (Canis familiaris)


name: Transport of MHC II:Ii complex along Golgi to TGN (Bos taurus)


name: isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Plasmodium falciparum)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate <=> (3R)-3-hydroxy-3-(thiiran-2-yl)propanenitrile + sulfate


name: 15-cis-phytoene + 5 A = 5 AH2 + all-trans-3,4-didehydrolycopene


name: 2-hydroxyhexacosanoyl-CoA + sphinganine = CoA + H(+) + N-(2-hydroxyhexacosanoyl)-sphinganine


name: a lactoside III(4)-a-Fuc-Lc4Cer + GDP-beta-L-fucose => a lactoside IV(2),III(4)-a-[Fuc]2-Lc4Cer + GDP + H(+)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Bos taurus)


name: UDP-N-acetyl-alpha-D-glucosamine(in) + UMP(out) <=> UDP-N-acetyl-alpha-D-glucosamine(out) + UMP(in)


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Gallus gallus)


name: Follicle-stimulating hormone receptor can bind FSH (Bos taurus)


name: M2-1 tetramer gets phosphorylated (Homo sapiens)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Bos taurus)


name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Canis familiaris)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Schizosaccharomyces pombe)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Schizosaccharomyces pombe)


name: abacavir [extracellular] => abacavir [cytosol] (Danio rerio)


name: Co-precorrin-5A + H2O <=> acetaldehyde + Co-precorrin-5B + H(+)


name: Degradation of ubiquitinated SKI/SKIL (Xenopus tropicalis)


name: O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin B = 6-hydroxytryprostatin B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Caenorhabditis elegans)


name: Aquaporins passively transport water into cells (Bos taurus)


name: (2S)-liquiritigenin + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + licodione + oxidized [NADPH--hemoprotein reductase]


name: p-Y-STATs translocate to nucleus (Drosophila melanogaster)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) => (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH


name: Deubiquitinated PTEN translocates to the cytosol (Danio rerio)


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Mus musculus)


name: AUF1 (hnRNP D0) is ubiquitinylated (Rattus norvegicus)


name: PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Bos taurus)


name: ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + H(+) + UDP


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Rattus norvegicus)


name: [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) = [TtuB sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Homo sapiens)


name: 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose => 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+)


name: a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP(+) = a 4alpha-methyl-3-oxosteroid + CO2 + NADPH


name: PPP1R3C binds to glycogen:GYG2:GYS2 (Homo sapiens)


name: ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) <=> ADP-D-glycero-beta-D-manno-heptose + diphosphate


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Homo sapiens)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Mus musculus)


name: (2E)-butenoyl-CoA + CO2 + FADH2 => FAD + glutaryl-CoA + 2 H(+)


name: PM20D1 hydrolyzes oleoyl-phe (Dictyostelium discoideum)


name: (2S,3S)-3-methylphenylalanine + 2-oxoglutarate => (3S)-2-oxo-3-phenylbutanoate + L-glutamate


name: cholesterol + hexadecanoyl-CoA <=> cholesteryl hexadecanoate + CoA


name: 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Homo sapiens)


name: 2-deoxyecdysone + phosphate => 2-deoxyecdysone 22-phosphate + H2O


name: 4',7,8-trihydroxyflavone + S-adenosyl-L-methionine <=> 7,8-dihydroxy-4'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Sus scrofa)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Xenopus tropicalis)


name: Dissociation of HSF1:HSP90 complex in the nucleus (Caenorhabditis elegans)


name: 2-methylbutyl hexanoate + CoA => 2-methylbutan-1-ol + hexanoyl-CoA


name: ATP + glycine + tRNA(Gly) <=> AMP + diphosphate + glycyl-tRNA(Gly)


name: ORC1 binds to H4K20me2 (Plasmodium falciparum)


name: MAPK6 is degraded by the 26S proteasome (Canis familiaris)


name: (2E,11Z)-eicosadienoyl-CoA + H(+) + NADPH => (11Z)-eicosenoyl-CoA + NADP(+)


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Drosophila melanogaster)


name: polyvinyl alcohol dehydrogenase (cytochrome) activity


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Bos taurus)


name: The high affinity receptor complex binds to G-protein (Sus scrofa)


name: (R)-carnitine + H(+) + NADPH + O2 <=> (3R)-3-hydroxy-4-oxobutanoate + H2O + NADP(+) + trimethylamine


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-tetradecanoyl-sn-glycerol + H(+) + phosphocholine


name: (2E)-hexadecenoyl-CoA + H(+) + NADPH <=> hexadecanoyl-CoA + NADP(+)


name: Phosphorylation of TSC2 by PKB (Drosophila melanogaster)


name: 2 Na(+)(out) + taurohyocholate(out) = 2 Na(+)(in) + taurohyocholate(in)


name: (S)-ureidoglycolate + 2 H(+) + H2O => CO2 + glyoxylate + 2 NH4(+)


name: keto-L-sorbose + NADP(+) => 5-dehydro-D-fructose + H(+) + NADPH


name: a secondary alcohol + NADP(+) = a ketone + H(+) + NADPH


name: (9Z)-octadecenoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol <=> 1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: alpha,alpha-trehalose 6-phosphate + phosphate <=> beta-D-glucose 1-phosphate + D-glucose 6-phosphate


name: A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin => AH2 + Latia luciferin + 2 O2


name: 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + NADP(+) => 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+) + NADPH


name: type 1 fibroblast growth factor receptor binding


name: (2E,6E)-farnesyl diphosphate = beta-sesquiphellandrene + diphosphate


name: Defective CYP11A1 does not cleave 20a,22b-DHCHOL (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-3-hydroxybutanoate + 2-oxoglutarate <=> (R)-2-hydroxyglutarate + acetoacetate


name: HSD11B2 dehydrogenates PREDL to PREDN (Schizosaccharomyces pombe)


name: p115-RhoGEF activation of RHOA (Drosophila melanogaster)


name: Class IV antihypertensives bind LTCC multimer (Xenopus tropicalis)


name: (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-tetrahomomethionine


name: L-arginyl-[protein] + NAD(+) <=> H(+) + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide


name: ATP + thiamine = ADP + H(+) + thiamine phosphate


name: S-adenosyl-L-methionine + scutellarein = H(+) + S-adenosyl-L-homocysteine + scutellarein 4'-methyl ether


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Canis familiaris)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Homo sapiens)


name: Active PLC-gamma1 dissociates from EGFR (Xenopus tropicalis)


name: P2Y14 receptor can bind to UDP-glucose (Xenopus tropicalis)


name: H2O + N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => (9Z,12Z)-octadecadienoate + H(+) + N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine


name: (E)-phenylacetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: D-xylose(in) + H(+)(in) = D-xylose(out) + H(+)(out)


name: Fibrillin C-terminal processing (Gallus gallus)


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Danio rerio)


name: Phosphorylation of L1 by ERK (Homo sapiens)


name: 2'-phospho-cyclic ADP-ribose + nicotinate => nicotinate-adenine dinucleotide phosphate


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Homo sapiens)


name: Second strand transfer by annealing complementary PBS sequences (Homo sapiens)


name: H(+) + NADPH + O2 + 2 rubrofusarin B => aurasperone A + 2 H2O + NADP(+)


name: HuR binds mRNAs in the nucleus (Mus musculus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Caenorhabditis elegans)


name: 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)


name: p-S291-PHF20 translocates to cytosol (Drosophila melanogaster)


name: 1-octadecanoylglycerone 3-phosphate + hexadecan-1-ol = 1-O-hexadecylglycerone 3-phosphate + H(+) + octadecanoate


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Plasmodium falciparum)


name: "Hydron translocation linked to the hydrolysis of diphosphate"


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)


name: 4-hydroxybenzoate + 2 H(+) + NADH + O2 = CO2 + H2O + hydroquinone + NAD(+)


name: C3PO hydrolyzes cleaved passenger strand (Gallus gallus)


name: PGLYRP2 binds bacterial peptidoglycan (Danio rerio)


name: a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GD1a (d18:1(4E)) + H2O


name: VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)


name: FUT3 transfers Fuc to Type 1 DSGG to form dsLeA (Canis familiaris)


name: H(+) + N,N-dihydroxy-L-tetrahomomethionine = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Drosophila melanogaster)


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Danio rerio)


name: SUMOylation of DDX5 with SUMO1 (Sus scrofa)


name: Collagen type X degradation by MMP1,2 (Homo sapiens)


name: CP110 and CEP97 dissociate from the centriole (Canis familiaris)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoate + O2 => (R)-2-hydroxyhexadecanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: 3'-phosphoadenylyl sulfate + taurochenodeoxycholate <=> adenosine 3',5'-bisphosphate + H(+) + taurochenodeoxycholate 7-sulfate


name: NADH + sanguinarine => dihydrosanguinarine + NAD(+)


name: inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate (Gallus gallus)


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Sus scrofa)


name: 2-hydroxytetracosenoyl-CoA + sphinganine <=> CoA + H(+) + N-(2-hydroxytetracosenoyl)-sphinganine


name: an anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + H(+) + UDP => an anthocyanidin 3-O-beta-D-sambubioside + UDP-alpha-D-glucose


name: Activated MET recruits GRB2-1:SOS1 (Rattus norvegicus)


name: CO2 + dGTP + H2O => formate + GTP + H(+)


name: UROD decarboxylates URO1 to COPRO1 (Canis familiaris)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA


name: CYP21A2 21-hydroxylates PROG (Sus scrofa)


name: (3S)-3-hydroxyadipyl-CoA <=> (E)-2,3-didehydroadipoyl-CoA + H2O


name: TFAP2A:TFAP2C, POU5F1, SOX2 and MYB bind the PAX7 gene (Homo sapiens)


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Canis familiaris)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Dictyostelium discoideum)


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => H2O + 2 oxidized [adrenodoxin] + secalciferol


name: (2E)-hexadecenoyl-CoA + H2O => (3S)-hydroxyhexadecanoyl-CoA


name: butylamine + H2O + NAD(+) <=> butanal + H(+) + NADH + NH4(+)


name: TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 (Rattus norvegicus)


name: ALOX15 oxidises 17(S)-Hp-DHA to PDX (Mus musculus)


name: p-hydroxyphenylpyruvate + glutamate <=> tyrosine + alpha-ketoglutarate (Mus musculus)


name: [PQQ precursor protein] + S-adenosyl-L-methionine = 5'-deoxyadenosine + E-Y cross-linked-[PQQ precursor protein] + H(+) + L-methionine


name: alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose => [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + H(+) + UDP


name: 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Mus musculus)


name: phosphate + S-methyl-5'-thioadenosine <=> adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: CYP3A4 oxidizes PREDN,PREDL (Homo sapiens)


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Danio rerio)


name: Formation of the PINCH-ILK-parvin complex (Rattus norvegicus)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA => a 2-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA


name: 2-oxoglutarate + pyridoxamine 5'-phosphate => L-glutamate + pyridoxal 5'-phosphate


name: CAD hexamer transforms CAP to N-carb-L-Asp (Drosophila melanogaster)


name: histidine => urocanate + NH4+ (Danio rerio)


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Mus musculus)


name: "lytic cellulose monooxygenase (C1-hydroxylating)"


name: Formation of the 43S pre-initiation complex (Saccharomyces cerevisiae)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycerol + H(+)


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Homo sapiens)


name: ADRM1:26S proteaseome binds UCHL5 (Rattus norvegicus)


name: Basigin binds MCT1, MCT3 and MCT4 (Sus scrofa)


name: ARL6:GTP and the BBSome bind ciliary cargo (Canis familiaris)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Mus musculus)


name: (S)-Malate <=> Fumarate + H2O (Saccharomyces cerevisiae)


name: (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O => 2-dehydro-3-deoxy-D-gluconate + NH4(+)


name: Exocytosis of ficolin-rich granule membrane proteins (Mus musculus)


name: Recruitment of VAV1 to p-6Y-SYK (Homo sapiens)


name: 1-carboxybiuret + H2O => NH4(+) + urea-1,3-dicarboxylate


name: 2 (S)-methylmalonyl-CoA + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH => C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)


name: SPRY2 binds CBL (Drosophila melanogaster)


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Rattus norvegicus)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Homo sapiens)


name: 6'''-deamino-6'''-hydroxyneomycin C + acetate => 2'''-acetyl-6'''-hydroxyneomycin C + H2O


name: 3'-phosphoadenylyl sulfate + a phenol <=> adenosine 3',5'-bisphosphate + an aryl sulfate + H(+)


name: phosphate + sucrose = alpha-D-glucose 1-phosphate + D-fructose


name: XYLB phosphorylates D-xylulose (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate <=> (1S,8aR)-delta-cadinene + diphosphate


name: Caspase-mediated cleavage of Tau (Canis familiaris)


name: 2-hydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin


name: a long-chain fatty acid + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> a long-chain fatty acyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Homo sapiens)


name: Alpha-defensins form biologically active dimers (Homo sapiens)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Sus scrofa)


name: 1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerol + a sphingomyelin <=> a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Mus musculus)


name: 1-hexadecanoyl-2-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol <=> (6Z,9Z,12Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin


name: a fatty acid + L-leucine => an N-(fatty acyl)-L-leucine + H2O


name: Superoxide reduces cytochrome c (Mus musculus)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Danio rerio)


name: (S)-beta-macrocarpene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: (2E)-dodecenedioyl-CoA + H2O => (3S)-hydroxydodecanedioyl-CoA


name: phycoviolobilin-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit] => (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit]


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Canis familiaris)


name: USP25 deubiquitinates DDX58 (Saccharomyces cerevisiae)


name: Dopamine synaptic vesicle docking and priming (Mus musculus)


name: USP48 cleaves polyubiquitin (Canis familiaris)


name: ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Homo sapiens)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Dictyostelium discoideum)


name: HLCS biotinylates ACACA:Mn2+ (Sus scrofa)


name: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] => 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Latent TGF-beta-1 is cleaved by FURIN (Bos taurus)


name: Cleavage of thymine by TDG glycosylase (Schizosaccharomyces pombe)


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA = (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: Elongating transcript encounters a lesion in the template (Mus musculus)


name: Recruitment of VAV and BTK to p-SLP-76 (Canis familiaris)


name: (4R)-4-hydroxy-L-lysine + CO2 + succinate => 2-oxoglutarate + L-lysine + O2


name: all-trans-beta-carotene + O2 = all-trans-10'-apo-beta-carotenal + beta-ionone


name: ATG3 transfers LC3 from ATG7 to ATG3 (Mus musculus)


name: GLI2,3 are degraded by the proteasome (Bos taurus)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin] <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: SLC36A1-mediated uptake of glycine, proline, and alanine (Drosophila melanogaster)


name: GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)


name: 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline


name: HAO2 tetramer oxidises 2OH-PALM (Sus scrofa)


name: sphinganine 1-phosphate => hexadecanal + phosphoethanolamine


name: (1S,5S)-sabinene + diphosphate => (2E)-geranyl diphosphate


name: TPX2 promotes AURKA autophosphorylation (Gallus gallus)


name: Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT (Homo sapiens)


name: BMX phosphorylates RUFY1 (Drosophila melanogaster)


name: 17-O-acetylajmaline + H2O => acetate + ajmaline + H(+)


name: ATPase-coupled 2-aminoethylphosphonate transporter activity


name: (2-aminoethyl)phosphonate(out) + ATP + H2O = (2-aminoethyl)phosphonate(in) + ADP + H(+) + phosphate


name: a 5'-end CoA-ribonucleoside in mRNA + H2O = 3'-dephospho-CoA + a 5'-end phospho-ribonucleoside in mRNA + H(+)


name: AMP + diphosphate + GMP + 2 H(+) => ATP + NH4(+) + XMP


name: 2'-deoxyguanosine + ATP <=> ADP + dGMP + H(+)


name: H2O + mycophenolyl-CoA <=> CoA + H(+) + mycophenolate


name: (2S)-2-acetolactate + CO2 => H(+) + 2 pyruvate


name: Release of acetylcholine at the synapse (Drosophila melanogaster)


name: 8-methylquinoline + A + H2O = 8-methylquinolin-2(1H)-one + AH2


name: 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: GEFs activate RhoA,B,C (Caenorhabditis elegans)


name: cirsimaritin + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + salvigenin


name: Formation of caspase-1 p10/p20 dimer (Canis familiaris)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Dictyostelium discoideum)


name: Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Bos taurus)


name: Pink1 is cleaved on healthy mitochondria (Mus musculus)


name: chloride(out) + dopamine(out) + Na(+)(out) = chloride(in) + dopamine(in) + Na(+)(in)


name: Beta-defensins 4A and 103 bind CCR2 (Canis familiaris)


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: RHOV binds effectors at the plasma membrane (Sus scrofa)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Xenopus tropicalis)


name: sphing-4-enine + tetradecanoate => H2O + N-tetradecanoylsphing-4-enine


name: glycochenodeoxycholate + NAD(+) => 7-oxoglycolithocholate + H(+) + NADH


name: Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Caenorhabditis elegans)


name: (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine in DNA => a thymidine dimer in DNA


name: OPTN recruits CYLD to the TNFR1 complex (Bos taurus)


name: TORC2 (mTOR) phosphorylates AKT at S473 (Rattus norvegicus)


name: a sphingoid 1-phosphate + H2O = a sphingoid base + phosphate


name: The SMAD2/3:SMAD4 complex transfers to the nucleus (Mus musculus)


name: TRPV1 binds TRPV1 blockers (Caenorhabditis elegans)


name: L-iditol + NAD(+) => H(+) + keto-L-sorbose + NADH


name: Endocytosis of TRAM (TICAM2) (Homo sapiens)


name: chloride(in) + D-alanine(in) + 2 Na(+)(in) => chloride(out) + D-alanine(out) + 2 Na(+)(out)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: N(pros)-phospho-L-histidyl-[protein] + N-acetyl-beta-D-muramate(out) => L-histidyl-[protein] + N-acetyl-beta-D-muramate 6-phosphate(in)


name: N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(527) in 16S rRNA + S-adenosyl-L-methionine


name: DENND1s exchange GTP for GDP on RAB35 (Sus scrofa)


name: PKC-delta phosphorylates CARD9 (Canis familiaris)


name: RANBP2 SUMOylates PML with SUMO2 (Mus musculus)


name: ADA catalyzes the deamination of (deoxy)adenosine (Rattus norvegicus)


name: an N-(2-hydroxyacyl)-sphinganine + UDP-alpha-D-galactose = an N-(2-hydroxyacyl)-beta-D-galactosyl-sphinganine + H(+) + UDP


name: 2-hydroxyethylphosphonate + CTP <=> cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + diphosphate


name: (2S)-2-amino-4-deoxychorismate <=> anthranilate + H(+) + pyruvate


name: H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate => (2S,6S)-2,6-diaminoheptanedioate + acetate


name: a monoacyl-sn-glycero-3-phosphocholine + H2O => a monoacylglycerol + H(+) + phosphocholine


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Mus musculus)


name: H2O + N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD(+) <=> 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: DNA polymerase delta polymerizes DNA across single stranded gap (Sus scrofa)


name: H(+) + malonyl-CoA + octadecanoyl-CoA <=> 3-oxoeicosanoyl-CoA + CO2 + CoA


name: Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Bos taurus)


name: 2-oxoglutarate(out) + prostaglandin E2(in) => 2-oxoglutarate(in) + prostaglandin E2(out)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + preaspterpenacid acid II => O2 + preaspterpenacid acid I + reduced [NADPH--hemoprotein reductase]


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Canis familiaris)


name: chlorophyllide a + 2 H(+) = Mg(2+) + pheophorbide a


name: 9-(10Z-heptadecenoyloxy)-octadecanoate + di-(10Z)-heptadecenoylglycerol => 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate


name: SLC26A3,6 exchange Cl- for HCO3- (Saccharomyces cerevisiae)


name: PI is exchanged with PC by PITPNB (Plasmodium falciparum)


name: IL4I1:FAD oxidises L-Phe to kPPV (Bos taurus)


name: a 2'-deoxyadenosine in double-stranded DNA + CO2 + glyoxal + succinate => 2-oxoglutarate + a 1,N(6)-etheno-2'-deoxyadenosine in double-stranded DNA + H2O + O2


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Canis familiaris)


name: Ubiquitinated Orc1 is degraded by the proteasome (Rattus norvegicus)


name: Defective CHSY1 does not transfer GalNAc to chondroitin (Homo sapiens)


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Sus scrofa)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Canis familiaris)


name: 4-hydroxybutan-2-one + H(+) + NADH + NH4(+) => 3-aminobutan-1-ol + H2O + NAD(+)


name: [HPr protein]-L-serine + diphosphate => [HPr protein]-O-phospho-L-serine + H(+) + phosphate


name: 3-oxohexadecanoyl-CoA + H(+) + NADH => (3S)-hydroxyhexadecanoyl-CoA + NAD(+)


name: 1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP


name: 1-acyl LPG is acylated to PG by LPGAT (Saccharomyces cerevisiae)


name: all-trans-octaprenol + ATP <=> ADP + all-trans-octaprenyl phosphate + H(+)


name: DDO oxidizes D-Asp to OA (Rattus norvegicus)


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Sus scrofa)


name: benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Sus scrofa)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1)


name: 2'-phospho-cyclic ADP-ribose + nicotinate = nicotinate-adenine dinucleotide phosphate


name: Muscarinic Acetylcholine Receptor M3 activates Gq (Homo sapiens)


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Rattus norvegicus)


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Danio rerio)


name: O2 + reduced [NADPH--hemoprotein reductase] + vitamin D2 => 25-hydroxyvitamin D2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADPH + O2 + tigecycline => 11a-hydroxytigecycline + H2O + NADP(+)


name: deoxycholate + NAD(+) <=> 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: AH2 + H(+) + S-(hercyn-2-yl)-L-cysteine S-oxide <=> A + ergothioneine + NH4(+) + pyruvate


name: UCHL1, UCHL3 cleave ubiquitin adducts (Sus scrofa)


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 = 7-epi-cylindrospermopsin + CO2 + succinate


name: (20S)-ginsenoside C-K + H(+) + UDP => (20S)-protopanaxadiol + UDP-alpha-D-glucose


name: (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H(+) + NADPH = (8Z,11Z,14Z)-eicosatrienoyl-CoA + NADP(+)


name: 4-coumaroyl-CoA + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside = a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Mus musculus)


name: 2,5-dioxovalerate dehydrogenase (NADP+) activity


name: 2-deoxy-scyllo-inosamine + NADP(+) => 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADPH


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Bos taurus)


name: an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Sus scrofa)


name: (4R)-hydroxyeicosasphinganine + a fatty acyl-CoA => CoA + H(+) + N-acyl-4-hydroxyeicosasphinganine


name: glandicoline B + S-adenosyl-L-methionine <=> H(+) + meleagrin + S-adenosyl-L-homocysteine


name: Palmostatin B binds RAS depalmitoylases (Caenorhabditis elegans)


name: Sialic acid binds SIGLEC (Xenopus tropicalis)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Bos taurus)


name: cytidine 2'-phosphate + H2O => cytidine + phosphate


name: cholestanol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-hydroxycholestanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + L-arginyl-[protein] <=> L-citrullyl-[protein] + NH4(+)


name: COX10 transforms heme to heme O (Homo sapiens)


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Sus scrofa)


name: KDM5A-D demethylate Me2K5-histone H3 (Sus scrofa)


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-(9Z-octadecenoyl)-glycerol => 1,2-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Caenorhabditis elegans)


name: ATG7:ATG3:LC3 dissociates (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acylglycerol <=> a 1-acyl-sn-glycero-3-phosphoethanolamine + a 2,3-diacyl-sn-glycerol


name: Aquaporins passively transport glycerol into cells (Xenopus tropicalis)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Bos taurus)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Sus scrofa)


name: L-homocysteine + S-methyl-L-methionine => H(+) + 2 L-methionine


name: N-carbamoylputrescine + NH4(+) => agmatine + H2O


name: C4b binds to target cell surface (Gallus gallus)


name: deoxycholoyl-CoA + NAD(+) = 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + H(+) + NADH


name: ADK phosphorylates RBV (Saccharomyces cerevisiae)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Homo sapiens)


name: Cytosolic folate export across the plasma membrane (Sus scrofa)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O => (6S)-5,6,7,8-tetrahydrofolate + L-serine


name: beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose <=> beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Dictyostelium discoideum)


name: GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Bos taurus)


name: CYSLTR1 binds CYSLTR1 antagonists (Rattus norvegicus)


name: (E)-caffeate + hydrocaffeoyl-CoA <=> (E)-caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)propanoate


name: 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+) => 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose


name: Phosphorylation of SHC by SYK kinase (Canis familiaris)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Drosophila melanogaster)


name: D-glucose + NADP(+) = 6-dehydro-D-glucose + H(+) + NADPH


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Rattus norvegicus)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Drosophila melanogaster)


name: CDP-glycerol + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate = 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: "teichoic acid glycerol-phosphate primase"


name: Coumarin is 7-hydroxylated by CYP2A6 (Drosophila melanogaster)


name: Hemes bind to CLEC1B dimer (Rattus norvegicus)


name: (3R)-hydroxy-(11Z,14Z,17Z)-eicosatrienoyl-CoA + NADP(+) => (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + H(+) + NADPH


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Sus scrofa)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-phenylalanine => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-phenylalanyl-[tubulin] + H2O


name: 3 AH2 + ATP + H2O + Ni-sirohydrochlorin a,c-diamide => 15,17(3)-seco-F430-17(3)-acid + 3 A + ADP + phosphate


name: EHD proteins interact with Rabenosyn-5 (Sus scrofa)


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Sus scrofa)


name: all-trans-13,14-dihydroretinal + H2O + NAD(+) => all-trans-13,14-dihydroretinoate + 2 H(+) + NADH


name: eNOS:Caveolin-1 complex binds to Nostrin (Homo sapiens)


name: A + H2O + quinolin-5-ol <=> 5-hydroxyquinolin-2(1H)-one + AH2


name: H(+) + H2O2 + retinoate => H2O + O2 + retinal


name: SUMOylation of XPC with SUMO1 (Homo sapiens)


name: 2'-O-methylcytidine(4) in tRNA(Gly)(GCC) + H(+) + S-adenosyl-L-homocysteine => cytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-methionine


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Drosophila melanogaster)


name: (2R)-2,3-dihydroxy-3-methylbutanoate => 3-methyl-2-oxobutanoate + H2O


name: H2O + N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine = L-asparagine + N-acetyl-D-glucosamine


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Bos taurus)


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Drosophila melanogaster)


name: STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Mus musculus)


name: a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol => a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+)


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Homo sapiens)


name: I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)


name: NR1H4 binds DCA, CDCA, LCHA (Danio rerio)


name: H2O + S-hexadecanoyl-L-cysteinyl-[protein] => H(+) + hexadecanoate + L-cysteinyl-[protein]


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Dictyostelium discoideum)


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Drosophila melanogaster)


name: Cu(2+)(out) + L-ascorbate(in) => Cu(+)(out) + H(+) + monodehydro-L-ascorbate radical(in)


name: H2O + S-acylglutathione => a carboxylate + glutathione + H(+)


name: Ubiquitination of stimulated EGFR (CBL) (Caenorhabditis elegans)


name: cholate + lithocholoyl-CoA <=> choloyl-CoA + lithocholate


name: NADP(+) + nonan-1-ol <=> H(+) + NADPH + nonanal


name: 2 chloride(out) + glycine betaine(out) + 3 Na(+)(out) <=> 2 chloride(in) + glycine betaine(in) + 3 Na(+)(in)


name: (2R,3S)-2,3-dimethylmalate => propanoate + pyruvate


name: a quinone + L-proline => (S)-1-pyrroline-5-carboxylate + a quinol + H(+)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine


name: dodecanedioyl-CoA + O2 <=> (2E)-dodecenedioyl-CoA + H2O2


name: Nuclear DUSPs dephosphorylate MAPKs (Mus musculus)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + H2O => beta-D-fructofuranosyl alpha-D-mannopyranoside + phosphate


name: DAG stimulates protein kinase C-delta (Saccharomyces cerevisiae)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Gallus gallus)


name: 2-acyl LPS is acylated to PS by LPSAT (Plasmodium falciparum)


name: P4HB binds Collagen chains (Caenorhabditis elegans)


name: Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Gallus gallus)


name: SLC7A3 (CAT-3)-mediated uptake of cationic amino acids (Xenopus tropicalis)


name: CO2 + dainate A + H2O + succinate => 2-oxoglutarate + N-geranyl-L-glutamate + O2


name: dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2 => dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+)


name: ferric-enterobactin transmembrane transporter activity


name: a 1-acylglycerol + an acyl-CoA = a 1,2-diacylglycerol + CoA


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Canis familiaris)


name: a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: 3 O2 + oleanolate + 3 reduced [NADPH--hemoprotein reductase] = gypsogenate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: a (2E)-enoyl fatty acid + ATP + holo-[ACP] => a (2E)-enoyl-[ACP] + AMP + diphosphate


name: 7-oxoresolvin D2 + H(+) + NADH => NAD(+) + resolvin D2


name: ATP + H2O + L-aspartate(out) = ADP + H(+) + L-aspartate(in) + phosphate


name: 2 2-acetylphloroglucinol => 1,3,5-trihydroxybenzene + 2,4-diacetylphloroglucinol + H(+)


name: Caspase-mediated cleavage of alpha adducin (Mus musculus)


name: acetyl-CoA + N-terminal L-methionyl-L-seryl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-seryl-[protein]


name: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + H(+) + H2O <=> 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + NH4(+)


name: PDPK1 binds PIP2 (Caenorhabditis elegans)


name: NKX2-5 binds the GATA4 gene (Homo sapiens)


name: H(+) + hexan-3-one + NADPH + O2 => H2O + NADP(+) + propyl propanoate


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Danio rerio)


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Canis familiaris)


name: 3-oxochol-4-en-22-oate + H(+) + NADH + O2 => 9alpha-hydroxy-3-oxochol-4-en-22-oate + H2O + NAD(+)


name: TAK1 phosphorylates MKK6 (Xenopus tropicalis)


name: [glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Caenorhabditis elegans)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: gastric inhibitory peptide receptor activity


name: p-Y705-STAT3 binds p-Y693-STAT4 (Gallus gallus)


name: (S)-malate(in) + 2 thiosulfate(out) => (S)-malate(out) + 2 thiosulfate(in)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Drosophila melanogaster)


name: p107 (RBL1) binds CyclinE/A:CDK2 (Caenorhabditis elegans)


name: Peroxynitrite enters the bacterium (Homo sapiens)


name: O2 + tetradecanoate <=> (2R)-2-hydroperoxytetradecanoate


name: PIAS2,3,4 SUMOylate RORA with SUMO1 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate => (+)-thujopsene + diphosphate


name: DHFR dimer binds DHFR inhibitors (Mus musculus)


name: 5,6,7,8-tetrahydromethanopterin + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] => 5-methyl-5,6,7,8-tetrahydromethanopterin + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: holo-[ACP] + malonyl-CoA => CoA + malonyl-[ACP]


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Canis familiaris)


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Homo sapiens)


name: Trimerization of cytosolic HSF1 (Gallus gallus)


name: 5-methylaminomethyl-S-(2E)-geranyl-thiouridine(34) in tRNA + H(+) + selenophosphate = (2E)-thiogeraniol + 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA


name: 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H(+) => chlorohydroquinone + O2


name: Transfer of SUMO3 from E1 to UBE2I (UBC9) (Homo sapiens)


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Saccharomyces cerevisiae)


name: UBQLNs bind UIM-containing adaptor proteins (Sus scrofa)


name: H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) => 2 H(+) + N-succinyl-L-glutamate + NADH


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Drosophila melanogaster)


name: H2O + N,N',N''-triacetylchitotriono-1,5-lactone = H(+) + N,N',N''-triacetylchitotrionate


name: choloyl-24-O-(beta-D-glucuronate) + UDP => cholate + UDP-alpha-D-glucuronate


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Gallus gallus)


name: Cytoslic carboxylases translocate to mitochondrial matrix (Dictyostelium discoideum)


name: ERK5 translocates to the nucleus (Rattus norvegicus)


name: H(+)(in) + L-glutamate(in) + L-glutamine(out) + Na(+)(in) => H(+)(out) + L-glutamate(out) + L-glutamine(in) + Na(+)(out)


name: Nephrin interacts with Podocin (Caenorhabditis elegans)


name: Phosphorylated MAPKs translocate into the nucleus (Homo sapiens)


name: glyoxylate + succinate => D-threo-isocitrate


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Danio rerio)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Xenopus tropicalis)


name: Association of mTERF with the termination sequence (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + UDP


name: choline(out) + n H(+)(in) <=> choline(in) + n H(+)(out)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Homo sapiens)


name: (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA + H(+) + NADPH <=> (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + NADP(+)


name: [pyruvate, water dikinase]-phosphate + AMP + H(+) => [pyruvate, water dikinase] + ADP


name: 2-aminoprop-2-enoate + a thiol => an S-substituted L-cysteine


name: linalool + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (6E)-8-oxolinalool + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine


name: chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity


name: 8-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoate + H2O = (8,11R,12S)-trihydroxy-(5Z,9E,14Z)-eicosatrienoate


name: DNA polymerase epsilon binds at the origin (Xenopus tropicalis)


name: arginine + H2O => ornithine + urea (Gallus gallus)


name: TRPV1 binds TRPV1 blockers (Homo sapiens)


name: Thiosulfate can transfer its sulfur atom to glutathione (Sus scrofa)


name: Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) (Homo sapiens)


name: Activated FGFR2 phosphorylates FRS3 (Rattus norvegicus)


name: p-Y705-STAT3 binds p-Y693-STAT4 (Homo sapiens)


name: (R)-carnitine + H(+) + NADH + O2 => (3R)-3-hydroxy-4-oxobutanoate + H2O + NAD(+) + trimethylamine


name: maltose + H2O => 2 D-glucose (maltase-glucoamylase) (Caenorhabditis elegans)


name: docosanedioate + 2 H(+) + NADH => 22-oxodocosanoate + H2O + NAD(+)


name: PIP3 recruits PDPK1 to the membrane (Plasmodium falciparum)


name: 3-hydroxypropanoate + ATP + CoA <=> 3-hydroxypropanoyl-CoA + AMP + diphosphate


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-guanosine) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + lovastatin <=> H(+) + lovastatin carboxylate


name: CDK2:CCNA phosphorylates TERF2 (Xenopus tropicalis)


name: (-)-echitovenine + CoA => (-)-minovincinine + acetyl-CoA


name: Hydroxyl radical reacts with the base and sugar moiety of DNA (Homo sapiens)


name: RNA polymerase II CTD heptapeptide repeat kinase activity


name: THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)


name: 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate = 16alpha,17alpha-estriol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: dimethylallyl diphosphate + siccayne = diphosphate + pestalodiol


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate


name: (3R)-hydroxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA = (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O


name: H2O + uroporphyrinogen III => hydroxymethylbilane


name: PANK2 phosphorylates PanK (Canis familiaris)


name: homophytochelatin synthase (dimmer forming) activity


name: 6-hydroxy pseudo-oxynicotine monooxygenase activity


name: (6S)-NADHX + ADP <=> AMP + H(+) + NADH + phosphate


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Saccharomyces cerevisiae)


name: 2 H2O + 4 hnu + 2 plastoquinone-9 => O2 + 2 plastoquinol-9


name: GDIs block activation of RHOA (Canis familiaris)


name: (5-hydroxyindol-3-yl)acetaldehyde + H2O + NAD(+) <=> (5-hydroxyindol-3-yl)acetate + 2 H(+) + NADH


name: FAD + H(+) + octanoyl-CoA => (2E)-octenoyl-CoA + FADH2


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Xenopus tropicalis)


name: ERO1B oxidizes P4HB (Dictyostelium discoideum)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Caenorhabditis elegans)


name: (S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate <=> 2-(3,5-dihydroxyphenyl)-2-oxoacetate + L-glutamate


name: Ca2+ influx through voltage gated Ca2+ channels (Mus musculus)


name: ATP + L-xylulose => ADP + H(+) + L-xylulose 5-phosphate


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Caenorhabditis elegans)


name: Activation of conventional Protein Kinase C (Dictyostelium discoideum)


name: an N-acetyl-alpha-D-glucosaminyl derivative + UDP-alpha-D-galactose => a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl derivative + H(+) + UDP


name: apo-[aequorin] + coelenterazine = apo-[aequorin]--coelenterazine


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + an acyl-CoA


name: 12-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 12,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated TP receptor binds G-proten Gq (Canis familiaris)


name: CBCAP complex binds 7-methylguanosine cap of snRNA (Homo sapiens)


name: IL12A:IL12B translocates from late endosome lumen to extracellular region (Bos taurus)


name: H(+) + oxidized [electron-transfer flavoprotein] + tetradecanoyl-CoA => (2E)-tetradecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2-methyleneglutarate + H2O => (S)-2-hydroxymethylglutarate


name: H2O + trioctadecanoylglycerol = 2,3-dioctadecanoyl-sn-glycerol + H(+) + octadecanoate


name: (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + octanoyl-CoA <=> (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + CoA


name: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate


name: CBL binds and ubiquitinates phosphorylated Sprouty (Gallus gallus)


name: 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: Active FLT3 phosphorylates CDKN1B (Canis familiaris)


name: H2O + NADP(+) + semiviriditoxin => (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + H(+) + NADPH + O2


name: I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen (Dictyostelium discoideum)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Sus scrofa)


name: CHRM1,3,5 bind acetylcholine (Xenopus tropicalis)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Xenopus tropicalis)


name: WLS:WNT complex is internalized for maturation into exosomes (Mus musculus)


name: H2O + sucrose 6(F)-phosphate <=> beta-D-fructose + beta-D-glucose 6-phosphate


name: Activated NTRK3 binds SRC (Gallus gallus)


name: p-VAV family:PIP3 binds RAC1:GDP (Gallus gallus)


name: 2 a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol <=> a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a 1,2-diacyl-sn-glycerol


name: TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine (Homo sapiens)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Homo sapiens)


name: CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5 (Homo sapiens)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Homo sapiens)


name: CD22 binds itself to form homo-oligomers (Xenopus tropicalis)


name: a (3R)-hydroxyacyl-[ACP] => a (2E)-enoyl-[ACP] + H2O


name: (+)-6-endo-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin] => (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin]


name: (2E)-thiogeraniol + 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA => 5-methylaminomethyl-S-(2E)-geranyl-thiouridine(34) in tRNA + H(+) + selenophosphate


name: germacrene A acid 8beta-hydroxylase activity


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Gallus gallus)


name: CO2 + H2O + phenyl phosphate => 4-hydroxybenzoate + H(+) + phosphate


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Xenopus tropicalis)


name: (2E)-octadecenoyl-CoA + H2O => (3R)-hydroxyoctadecanoyl-CoA


name: 1,5-anhydro-D-fructose => H2O + microthecin


name: 2-aminoprop-2-enoate + phenol => L-tyrosine


name: Activated FGFR2 phosphorylates FRS2 (Mus musculus)


name: H2O + N-dodecanoylethanolamine => dodecanoate + ethanolamine


name: (20S)-ginsenoside C-K + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + O2 + reduced [NADPH--hemoprotein reductase]


name: sequestered tissue factor -> tissue factor (Rattus norvegicus)


name: RP2 activates the GTPase activity of ARL3 (Homo sapiens)


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Saccharomyces cerevisiae)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Homo sapiens)


name: Formation of the CE:GMP intermediate complex (Homo sapiens)


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Gallus gallus)


name: MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end (Homo sapiens)


name: Formation of PPAT dimers (Gallus gallus)


name: Monoiodinated tyrosine can be deiodinated (Bos taurus)


name: lanosterol + O2 + reduced [NADPH--hemoprotein reductase] => 32-hydroxylanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate = A + semiviriditoxin


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Rattus norvegicus)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Bos taurus)


name: RHOA:GTP translocates to the ER membrane (Saccharomyces cerevisiae)


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Homo sapiens)


name: abscisic acid transmembrane transporter activity


name: PRDM4 translocates to the nucleus (Homo sapiens)


name: GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 (Homo sapiens)


name: (E)-feruloyl-CoA + galactarate => 2-O-[(E)-feruloyl]-D-galactarate + CoA


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Gallus gallus)


name: (S)-reticuline + S-adenosyl-L-methionine <=> (S)-codamine + H(+) + S-adenosyl-L-homocysteine


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: ADP + ADP <=> AMP + ATP [AK2] (Drosophila melanogaster)


name: desmethylxanthohumol + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + xanthohumol


name: H2O + mutildienyl diphosphate <=> diphosphate + premutilin


name: (S)-versiconol + acetate + H(+) => (3S)-versiconol acetate + H2O


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Sus scrofa)


name: SCF-beta-TrCP ubiquitinylates IkB (Mus musculus)


name: (25R)-4beta,26-dihydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-3beta,4beta-dihydroxycholest-5-en-26-al + 2 H2O + 2 oxidized [adrenodoxin]


name: 2 sucrose <=> 1(F)-beta-D-fructosylsucrose + D-glucose


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Caenorhabditis elegans)


name: Surface deployment of platelet dense granule membrane components (Danio rerio)


name: beta-D-galactosyl-(1<->1')-N-octadecanoylsphing-4-enine + H2O <=> D-galactose + N-octadecanoylsphing-4-enine


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: TOPORS SUMOylates IKBKE with SUMO1 (Homo sapiens)


name: Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX (Bos taurus)


name: PIN1 binds phosphorylated PIP4K2B (Schizosaccharomyces pombe)


name: AMP + H2O => IMP + NH4+ (AMPD) (Sus scrofa)


name: inositol 1,3,4,5 tetrakisphosphate binding


name: carboxymethoxysuccinate = fumarate + glycolate


name: 5alpha-androst-1-ene-3,17-dione + H2O => 1-hydroxy-5alpha-androstan-3,17-dione


name: Assembly of the retrograde IFT train (Sus scrofa)


name: NADP(+) + octadecan-1-ol = H(+) + NADPH + octadecanal


name: a hydroperoxyeicosatetraenoate => a hydroxy-epoxy-eicosatetraenoate


name: SOD1:Zn2+ apoenzyme binds CCS:Cu1+ (mitochondrial) (Homo sapiens)


name: ATP + erythritol => ADP + D-erythritol 4-phosphate + H(+)


name: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH


name: "diacetyl reductase [(R)-acetoin forming]"


name: 2-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O


name: PRTPRF, PTPRS, PTPRD bind LRRC4B (Homo sapiens)


name: (E)-4-coumaroyl-CoA + AMP + H(+) => (E)-4-coumaroyl-AMP + CoA


name: ent-cassa-12,15-dien-2beta,3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] => ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Bos taurus)


name: 4-(phosphooxy)-L-threonine + ADP + H(+) => 4-hydroxy-L-threonine + ATP


name: 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase]


name: SUMOylation of TOP1 with SUMO1 (Schizosaccharomyces pombe)


name: (S)-3-hydroxyisobutanoyl-CoA + H2O => (S)-3-hydroxy-2-methylpropanoate + CoA + H(+)


name: FOXO4:ATXN3 binds SOD2 gene promoter (Homo sapiens)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O <=> 1-O-alkyl-sn-glycero-3-phosphate + a fatty acid + H(+)


name: Initiation of SAHF formation (Rattus norvegicus)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Gallus gallus)


name: ganglioside GM2 (d18:1(4E)/18:0) + H2O = ganglioside GA2 (d18:1(4E)/18:0) + N-acetylneuraminate


name: (5R)-5-hydroxy-L-lysyl-[collagen] + H2O2 + L-methionyl-[collagen] => [collagen]-(5R)-5-hydroxy-L-lysyl-N-S-L-methionyl-[collagen] + H(+) + 2 H2O


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Rattus norvegicus)


name: 2 monodehydro-L-ascorbate radical = L-ascorbate + L-dehydroascorbate


name: LRRC16A binds F-actin capping protein (Homo sapiens)


name: Calcium Influx through Voltage-gated Calcium Channels (Sus scrofa)


name: D-glucose(out) + 2 Na(+)(out) = D-glucose(in) + 2 Na(+)(in)


name: a 2-oxocarboxylate + a quinol => a (2R)-2-hydroxycarboxylate + a quinone


name: ACSM2B-like proteins transform ST to ST-CoA (Canis familiaris)


name: Caspase-mediated cleavage of GAS2 (Mus musculus)


name: an aromatic carboxylate + H(+) + H2O2 => an aromatic aldehyde + H2O + O2


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: gibberellin A24 + H(+) + O2 => CO2 + gibberellin A9 + H2O


name: Exocytosis of specific granule lumen proteins (Bos taurus)


name: 5-hydroxy-3-methyl-L-tyrosine + S-adenosyl-L-methionine <=> 5-hydroxy-3-methyl-O-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: (E)-isoeugenol + acetate + NADP(+) = (E)-coniferyl acetate + NADPH


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Rattus norvegicus)


name: prunetin-4'-O-beta-D-glucuronide + UDP => prunetin + UDP-alpha-D-glucuronate


name: a 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + H(+) + NADH + O2 => a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + 2 H2O + NAD(+)


name: Acetylcholine synaptic vesicle docking and priming (Caenorhabditis elegans)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Sus scrofa)


name: RBP3 transports 11cRAL to rod photoreceptor outer segment (Sus scrofa)


name: poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)


name: Transport of L1 into endosomes (Dictyostelium discoideum)


name: amino acid:monoatomic cation symporter activity


name: D-glucarate => 5-dehydro-4-deoxy-D-glucarate + H2O


name: H2O + nicotinamide => NH4(+) + nicotinate


name: FeHM dissociates from MetHb (Canis familiaris)


name: SPHK2 phosphorylates sphingoid (Schizosaccharomyces pombe)


name: AcK-NFE2L2 binds the TXN gene (Homo sapiens)


name: ATPase-coupled inorganic anion transmembrane transporter activity


name: p-Y705,S727-STAT3 dimerizes (Mus musculus)


name: H2O + isomaltose = alpha-D-glucose + D-glucose


name: NF-kB migrates to the nucleus and turns on transcription (Bos taurus)


name: adenosylcobinamide kinase (GTP-specific) activity


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Rattus norvegicus)


name: 45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + 5,7-dihydroxy-4-methylphthalide = 4-farnesyl-3,5-dihydroxy-6-methylphthalide + diphosphate


name: ADP + H(+) + N-acetyl-L-aspartyl-L-glutamate(out) + phosphate => ATP + H2O + N-acetyl-L-aspartyl-L-glutamate(in)


name: a secondary alcohol + NAD(+) <=> a ketone + H(+) + NADH


name: RNLS:FAD oxidises dh-beta-NAD to NAD+ (Danio rerio)


name: Release of docked serotonin loaded synaptic vesicle (Mus musculus)


name: glutathioselenol + NADPH = glutathione + hydrogenselenide + NADP(+)


name: KCNIP3 binds NPAS4 gene promoter (Homo sapiens)


name: C5a receptor binds C5a anaphylatoxin (Homo sapiens)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Bos taurus)


name: AXIN is ubiquitinated by SMURF2 (Bos taurus)


name: dimethylamine + formaldehyde => H(+) + trimethylamine N-oxide


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Plasmodium falciparum)


name: 7-deoxyloganate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + loganate + oxidized [NADPH--hemoprotein reductase]


name: alpha-maltotetraose + phosphate <=> alpha-D-glucose 1-phosphate + alpha-maltotriose


name: Formation of CSL NCOR corepressor complex (Sus scrofa)


name: 9-cis-10'-apo-beta-carotenal + 2 O2 => (11R)-carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal


name: 2-oxohexadecanoate + H2O2 => 2-hydroxyhexadecanoate + O2


name: carbovir + IMP => carbovir monophosphate + inosine (Mus musculus)


name: 9-cis-10'-apo-beta-carotenal cleavage oxygenase activity


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Gallus gallus)


name: Trans-autophosphorylation of ERBB4 homodimers (Gallus gallus)


name: Phosphorylation of PF2K-Pase by PKA catalytic subunit (Homo sapiens)


name: Collagen type III degradation by MMP15 (Mus musculus)


name: agmatine + H2O + O2 <=> 4-guanidinobutanal + H2O2 + NH4(+)


name: (2E,6E)-farnesyl diphosphate + H2O <=> 5-hydroxy-alpha-gurjunene + diphosphate


name: Internalization of gap junction plaques (Caenorhabditis elegans)


name: 17beta-hydroxy-5beta-estran-3-one + NADP(+) => 17beta-hydroxyestr-4-en-3-one + H(+) + NADPH


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Mus musculus)


name: CHEK2 phosphorylates BRCA1 (Mus musculus)


name: Calcineurin binds NFATC1,2,3 (Sus scrofa)


name: MBTPS1 (S1P) cleaves CREB3L3 (Sus scrofa)


name: GLI3R translocates to the nucleus (Xenopus tropicalis)


name: CDO binds promyogenic cadherins (Xenopus tropicalis)


name: AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Gallus gallus)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Saccharomyces cerevisiae)


name: (9Z)-octadecenoyl-CoA + 1-decanoylglycerol <=> 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: 4-hydroxy-3-all-trans-octaprenylbenzoate + H(+) => 2-all-trans-octaprenylphenol + CO2


name: DENND5A,B exchange GTP for GDP on RAB39 (Gallus gallus)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Mus musculus)


name: H2O + trans-urocanate => 4-imidazolone-5-propanoate


name: a fatty acyl-CoA + hexadecasphinganine <=> CoA + H(+) + N-acylhexadecasphinganine


name: dGTP + 2 H2O = dGMP + 2 H(+) + 2 phosphate


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: CES1,CES2 hydrolyze ASA- to ST (Xenopus tropicalis)


name: Hemopexin binds Hemes (Drosophila melanogaster)


name: (2E)-hexadecenedioyl-CoA + H2O => (3S)-hydroxyhexadecanedioyl-CoA


name: PDGF dimer binds two receptors simultaneously (Bos taurus)


name: erythromycin B + H(+) + S-adenosyl-L-homocysteine => erythromycin D + S-adenosyl-L-methionine


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Gallus gallus)


name: ATP + D-tyrosine + tRNA(Tyr) <=> AMP + D-tyrosyl-tRNA(Tyr) + diphosphate + H(+)


name: H(+) + NADPH + yaequinolone D = H2O + NADP(+) + penigequinolone B


name: alpha-D-glucose 1-phosphate + ATP <=> ADP + alpha-D-glucose 1,6-bisphosphate + H(+)


name: ATP + N-(D-erythrulosyl)-cadaverine <=> ADP + H(+) + N-(3-O-phospho-D-erythrulosyl)-cadaverine


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Rattus norvegicus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: D-cellobiose + H2O = beta-D-glucose + D-glucose


name: RNA polymerase III cis-regulatory region sequence-specific DNA binding


name: NOTCH1 PEST domain mutants bind DLL1  (Homo sapiens)


name: KRAB-ZNF / KAP Interaction (Drosophila melanogaster)


name: CoA + N(3)-oxalyl-L-2,3-diaminopropanoate => (S)-2,3-diaminopropanoate + oxalyl-CoA


name: L-alanine(in) + L-glutamine(out) + Na(+)(in) => L-alanine(out) + L-glutamine(in) + Na(+)(out)


name: dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + L-glutamate => 2-oxoglutarate + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Xenopus tropicalis)


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Mus musculus)


name: eIF3 and eIF1A bind to the 40S subunit (Plasmodium falciparum)


name: FA anion flip-flops to the opposite surface (Drosophila melanogaster)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Canis familiaris)


name: F-actin capping protein is a heterodimer (Xenopus tropicalis)


name: HTRA2 degrades NDUFA13 (GRIM-19) (Homo sapiens)


name: an alpha-Kdo-(2->6)-lipid IVA + ATP = a 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA + ADP + H(+)


name: FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Canis familiaris)


name: beta-acoradiene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (4R)-hydroxy-(6R)-2,2,6-trimethylcyclohexanone + NAD(+) = (6R)-2,2,6-trimethyl-1,4-cyclohexanedione + H(+) + NADH


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(13Z,16Z,19Z)-docosatrienoyl-CoA + CO2 + CoA


name: 2 AH2 + all-trans-4,4'-diaponeurosporene + 2 O2 <=> 4,4'-diaponeurosporenal + 2 A + 3 H2O


name: (2S)-3-sulfopropanediol => 3-oxopropane-1-sulfonate + H2O


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Dictyostelium discoideum)


name: G13 activation by TP receptor (Gallus gallus)


name: MT-MMPs are sorted to the plasma membrane (Bos taurus)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Drosophila melanogaster)


name: H(+) + N,N-dihydroxy-L-pentahomomethionine => (E)-8-(methylsulfanyl)octanal oxime + CO2 + H2O


name: H(+) + o-quinone methide + penilactone D = penilactone B


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Plasmodium falciparum)


name: cyclohexane-1,3-dione + H2O <=> 5-oxohexanoate + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate + 3 AH2 => 3 A + phytyl diphosphate


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Sus scrofa)


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Sus scrofa)


name: NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP (Bos taurus)


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Dictyostelium discoideum)


name: 2-oxopentanoate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminopentanoate


name: beta-NGF dimer binds to TrkA receptor (Canis familiaris)


name: 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADH => 2-deoxy-scyllo-inosamine + NAD(+)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine = 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Canis familiaris)


name: H2O + prostaglandin F2alpha-CoA = CoA + H(+) + prostaglandin F2alpha


name: Secretion and activation of the latent large complex of TGF-beta-1 (Homo sapiens)


name: (2R,3S)-homoisocitrate + NAD(+) => 2-oxoadipate + CO2 + NADH


name: Activated FGFR4 binds FRS3 (Canis familiaris)


name: capsidiol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => (+)-5-epi-aristolochene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: alpha-tocotrienol + H(+) + S-adenosyl-L-homocysteine => gamma-tocotrienol + S-adenosyl-L-methionine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-diphosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + phosphate


name: Translocation of NuMA to the centrosomes (Rattus norvegicus)


name: CTP(out) + IDP(in) <=> CTP(in) + IDP(out)


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + NH4(+) => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + phosphate


name: 2xPDXK:2xZn2+ phosphorylates PXA (Caenorhabditis elegans)


name: (2R)-3-phospho-glyceroyl phosphate + [phosphate](n) = (2R)-3-phosphoglycerate + [phosphate](n+1)


name: Hydrolysis of choloyl-CoA to cholate and CoASH (Xenopus tropicalis)


name: a 5'-end FAD-phospho-ribonucleoside in mRNA + H2O => a 5'-end phospho-ribonucleoside in mRNA + FAD + H(+)


name: ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA (Homo sapiens)


name: Migfilin interacts with VASP (Mus musculus)


name: Defective CUBN does not transport GIF:Cbl (Homo sapiens)


name: H(+) + NADH + O2 + propene <=> 1,2-epoxypropane + H2O + NAD(+)


name: DHNTP is dephosphorylated by PTPS to PTHP (Danio rerio)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)


name: dihydrocarvone + H(+) + NADH => dihydrocarveol + NAD(+)


name: CatSper Channel Mediated Calcium Transport (Rattus norvegicus)


name: 4-nitrobenzaldehyde + H(+) + NADPH <=> 4-nitrobenzyl alcohol + NADP(+)


name: H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate


name: 4-CDP-2-C-methyl-D-erythritol 2-phosphate <=> 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP


name: ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE (Danio rerio)


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Homo sapiens)


name: a ribonucleoside 3'-phosphate + H2O => a ribonucleoside + phosphate


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Canis familiaris)


name: 2-trans,4-trans-xanthoxin + NAD(+) <=> 2-trans-(+)-abscisic aldehyde + H(+) + NADH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: AMPK (complex) phosphorylates ULK1 (complex) (Caenorhabditis elegans)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Caenorhabditis elegans)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Canis familiaris)


name: Recruitment of POLB to oxidatively damaged AP site (Xenopus tropicalis)


name: FAR2 reduces PalmCoA to HXOL (Bos taurus)


name: H(+) + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine => adenosine(58) in tRNA + S-adenosyl-L-methionine


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Canis familiaris)


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Canis familiaris)


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Xenopus tropicalis)


name: Activated FGFR1 phosphorylates FRS3 (Bos taurus)


name: 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + H2O <=> 1D-myo-inositol 1,2,3,6-tetrakisphosphate + phosphate


name: ASPG hydrolyses L-Asn to L-Asp (Mus musculus)


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Bos taurus)


name: a cholesterol ester + H2O = a fatty acid + cholesterol + H(+)


name: DHCR24 reduces ZYMOL to ZYMSTNL (Danio rerio)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Danio rerio)


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH <=> a long-chain fatty acid + n CO2 + (n+1) CoA + 2n NADP(+)


name: RAR:RXR binds SUMO-CRABP2:atRA (Bos taurus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2


name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Canis familiaris)


name: PXMP2 trimer transports glycolate from cytosol to peroxisomal matrix (Homo sapiens)


name: TRIP11:IFT20 dissociates (Gallus gallus)


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-12-hydroperoxy-20-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: MYLIP dimer ubiquitinates VLDLR on Lys-839 (Bos taurus)


name: FDPS dimer transfers IPPP to GPP (Sus scrofa)


name: a monosubstituted aliphatic (S)-hydroxynitrile = an aldehyde + hydrogen cyanide


name: STAB2:ligand is endocytosed (Mus musculus)


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Plasmodium falciparum)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Saccharomyces cerevisiae)


name: (3S)-3-hydroxypentanoyl-CoA + H2O = (3S)-3-hydroxypentanoate + CoA + H(+)


name: AH2 + cremeomycin <=> 2-hydroxy-4-methoxybenzoate + A + N2


name: 5-valerolactone + H2O + NADP(+) => cyclopentanone + H(+) + NADPH + O2


name: ANKH transports PPi from cytosol to extracellular region (Xenopus tropicalis)


name: (9Z)-octadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin]


name: Activation of Ca2+ activated Potassium channels with large conductance (Gallus gallus)


name: PROCR binds Protein C (Canis familiaris)


name: MAP2K6 phosphorylates PIP4K2B (Caenorhabditis elegans)


name: sulfite transmembrane transporter activity


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Bos taurus)


name: CHOL translocates from lysosome membrane to ER membrane (Rattus norvegicus)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Canis familiaris)


name: phosphate + pseudouridine => H2O + psi-UMP


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Xenopus tropicalis)


name: AMP + 2 H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein]


name: Secretion of transmembrane collagens (Rattus norvegicus)


name: MAP2K1 phosphorylates MAPK3 (Schizosaccharomyces pombe)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Xenopus tropicalis)


name: glycine(out) + L-phenylalanine(in) => glycine(in) + L-phenylalanine(out)


name: 2-methylpropanal + hydrogen cyanide <=> (2S)-2-hydroxy-3-methylbutanenitrile


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: L-arginyl-[protein] + NAD(+) = ADP-riboxanated L-argininyl-[protein] + H(+) + NH4(+) + nicotinamide


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Homo sapiens)


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Drosophila melanogaster)


name: an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-N-acetyl-alpha-D-galactosamine <=> an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H(+) + UDP


name: SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)


name: AMP + D-tryptophan + diphosphate + H(+) => ATP + H2O + L-tryptophan


name: SUMOylation of MKL1 with SUMO1 (Sus scrofa)


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane + H2O = GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: formaldehyde + H2O + NAD(+) => formate + 2 H(+) + NADH


name: [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose => [(1->4)-alpha-D-glucosyl](n+1) + ADP + H(+)


name: MVB Vesicle Formation (Drosophila melanogaster)


name: ACSF3 ligates CoA-SH to VLCFA (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: dTDP-beta-L-rhamnose + L-arginyl-[protein] => dTDP + H(+) + N(omega)-(alpha-L-rhamnosyl)-L-arginyl-[protein]


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: GALK1 phosphorylates Gal to Gal1P (Mus musculus)


name: 2-hydroxymethyl-3-pentylphenol + O2 + reduced [NADPH--hemoprotein reductase] = (8S)-annullatin E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Trimming of peptides in ER (Rattus norvegicus)


name: (1S,5R)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase]


name: Interaction of PECAM-1 and SHP-2 (Mus musculus)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Canis familiaris)


name: cyclohexanecarbaldehyde + hydrogen cyanide = (2S)-2-cyclohexyl-2-hydroxyacetonitrile


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Drosophila melanogaster)


name: Initial activation of proMMP13 by MMP3 (Mus musculus)


name: E pentamer is transported to the Golgi (Homo sapiens)


name: PLK1 binds phosphorylated condensin II complex (Caenorhabditis elegans)


name: PIAS4 SUMOylates RNF168 with SUMO1 (Homo sapiens)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Bos taurus)


name: chlorotoluron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3-(3-chloro-4-methylphenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ethylene receptor histidine kinase activity


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Sus scrofa)


name: Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)


name: Inactivation of PLC beta (Rattus norvegicus)


name: glycerol + NADP(+) <=> D-glyceraldehyde + H(+) + NADPH


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Gallus gallus)


name: Defective GNE does not hydrolyse UDP-GlcNAc (Homo sapiens)


name: ADP(in) + diphosphate(out) => ADP(out) + diphosphate(in)


name: Exocytosis of azurophil granule membrane proteins (Xenopus tropicalis)


name: rifamycin SV hemiaminal => H(+) + rifamycin SV ortho-naphthoquinone carboxamide


name: mycothiol conjugates with electrophilic xenobiotic (Mycobacterium tuberculosis)


name: fumarate + L-cysteinyl-[protein] => S-(2-succinyl)-L-cysteinyl-[protein]


name: 3-(methylsulfanyl)acryloyl-CoA + H2O => 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA


name: H2O + N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD(+) => 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: XPO1 binds the beta-catenin:CBY complex (Rattus norvegicus)


name: NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Canis familiaris)


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Bos taurus)


name: Phosphorylation and activation of eIF4G by activated S6K1 (Canis familiaris)


name: formate + H(+) + menaquinone-8 <=> CO2 + menaquinol-8


name: CBL dissociates from ubiquitinated p-SPRY2 (Danio rerio)


name: 4,4-dihydroxy-all-trans-beta-carotene + A + H2O => 4-hydroxy-all-trans-beta-carotene + AH2 + O2


name: factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) (Homo sapiens)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Sus scrofa)


name: (6E)-8-hydroxygeranial + NAD(+) => (6E)-8-oxogeranial + H(+) + NADH


name: SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Mus musculus)


name: Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 19-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Rattus norvegicus)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR2 (Mus musculus)


name: oxidoreductase activity, acting on metal ions


name: MASTL (GWL) phosphorylates ARPP19 (Homo sapiens)


name: (S)-mandelate + A => AH2 + phenylglyoxylate


name: 4-methyl-3-oxopentanoyl-[ACP] + CO2 + CoA => 2-methylpropanoyl-CoA + H(+) + malonyl-[ACP]


name: PGLYRP2 binds bacterial peptidoglycan (Homo sapiens)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Schizosaccharomyces pombe)


name: Initial activation of proMMP2 by MMP1, 7 (Gallus gallus)


name: PA is dephosphorylated to DAG by LPIN (Xenopus tropicalis)


name: 2,3-dihydroxyindole + O2 <=> anthranilate + CO2 + H(+)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Caenorhabditis elegans)


name: 2-oxoglutarate + 4-amino-L-phenylalanine => 3-(4-aminophenyl)pyruvate + L-glutamate


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Dictyostelium discoideum)


name: H2O + peracetic acid => acetate + H(+) + H2O2


name: Syndecans 2, (4) bind TGFB1 (Sus scrofa)


name: Interleukin-27 translocates from the ER lumen to the extracellular region (Rattus norvegicus)


name: Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL (Homo sapiens)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Xenopus tropicalis)


name: CYP4F11 16-hydroxylates 3OH-PALM (Rattus norvegicus)


name: 7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + 2 H(+) + L-methionine


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Sus scrofa)


name: Tyrosine kinases phosphorylate the receptor (Homo sapiens)


name: KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 (Rattus norvegicus)


name: DNMT3A:DNMT3L binds chromatin (Homo sapiens)


name: SPHK2 phosphorylates sphingoid (Xenopus tropicalis)


name: 6 (S)-methylmalonyl-CoA + 12 H(+) + malonyl-CoA + 5 NADPH => 7 CO2 + 7 CoA + 2 H2O + 5 NADP(+) + narbonolide


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Rattus norvegicus)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Bos taurus)


name: Disassociation of Telomerase RNP and the Chromosome End (Bos taurus)


name: Aquaporins passively transport water out of cells (Rattus norvegicus)


name: LPA-binding receptors bind LPA (Bos taurus)


name: ABCC1 transports cytosolic RCbl to extracellular region (Saccharomyces cerevisiae)


name: EP300 is recruited to MYC and BCL2 genes (Drosophila melanogaster)


name: Caspase mediated cleavage of beta-catenin (Gallus gallus)


name: acetoacetyl-CoA + AMP + diphosphate => acetoacetate + ATP + CoA


name: GSS:Mg2+ dimer synthesizes GSH (Mus musculus)


name: SMURF1 binds phosphorylated PARD6A (Canis familiaris)


name: (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+) => glucoraphanin + H2O


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Mus musculus)


name: PE is methylated to PC by PEMT (Danio rerio)


name: Interaction of Tie2 and Ang4 (Mus musculus)


name: FANCD2 deubiquitination by USP1:WDR48 (Homo sapiens)


name: UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity


name: MME:Zn2+ hydrolyses AGT(34-42) (Homo sapiens)


name: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Mus musculus)


name: Release of GNB5:RGS dimers from CCT/TRiC (Rattus norvegicus)


name: 2-methylbutyronitrile + H(+) + NADPH + O2 => 2-hydroxy-2-methylbutanenitrile + H2O + NADP(+)


name: Aquaporin-9 passively transports glycerol into cell (Saccharomyces cerevisiae)


name: 2-cis,4-trans-xanthoxin + NAD(+) <=> 2-cis-(+)-abscisic aldehyde + H(+) + NADH


name: ATP + N(1)-(3,4-dihydroxybenzoyl)-N(8)-citryl-spermidine + spermidine = AMP + diphosphate + H(+) + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine)


name: Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA (Bos taurus)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> (+)-kolavenyl diphosphate


name: Parenchymal atROL translocates to HSCs (Rattus norvegicus)


name: ATP + beta-alanine + histamine => AMP + carcinine + diphosphate + H(+)


name: Activated NTRK3 promotes SRC autophosphorylation (Mus musculus)


name: ATP(in) + CoA(in) + docosanoate(out) + H(+)(out) = AMP(in) + diphosphate(in) + docosanoyl-CoA(in) + H(+)(in)


name: diglucosyl-enterobactin + H2O <=> H(+) + N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2


name: Proton-coupled di- and tri-peptide cotransport (Gallus gallus)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Bos taurus)


name: PLK2 phosphorylates CENPJ (Homo sapiens)


name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Homo sapiens)


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Bos taurus)


name: Activation of STAT5a/b by JAK2 (Canis familiaris)


name: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite => 4-nitro-6-oxohepta-2,4-dienedioate


name: 2-deoxystreptamine + UDP-N-acetyl-alpha-D-glucosamine => 2'-N-acetylparomamine + H(+) + UDP


name: (E)-4-oxonon-2-en-1-ol + NADP(+) <=> (E)-4-oxonon-2-enal + H(+) + NADPH


name: a nucleoside + phosphate => a nucleoside 5'-phosphate + H2O


name: 2 H(+) + O2 + pheophorbide a + 2 reduced [2Fe-2S]-[ferredoxin] = 2 oxidized [2Fe-2S]-[ferredoxin] + red chlorophyll catabolite


name: PSGs bind proteoglycans and TGF-beta1 (Mus musculus)


name: Electron transfer from reduced cytochrome c to molecular oxygen (Rattus norvegicus)


name: FADK1 interaction with DCC (Homo sapiens)


name: ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Sus scrofa)


name: Activated MET binds GAB1 and GRB2 (Xenopus tropicalis)


name: 2-oxoglutarate + 4-hydroxy-L-glutamate <=> 4-hydroxy-2-oxoglutarate + L-glutamate


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Canis familiaris)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Caenorhabditis elegans)


name: Caspase-mediated cleavage of claspin (Bos taurus)


name: ladanein + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + scutellarein 4'-methyl ether


name: H2O + Met-enkephalin => L-phenylalanyl-L-methionine + L-tyrosylglycylglycine


name: 1-deoxy-D-xylulose 5-phosphate + A + methanethiol => AH2 + S-methyl-1-thio-D-xylulose 5-phosphate


name: Sequestration of BAD protein by 14-3-3 (Mus musculus)


name: (S)-2-ureidoglycine + H2O = glyoxylate + NH4(+) + urea


name: MICAL1 produces NADP+, H2O2 (Caenorhabditis elegans)


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Sus scrofa)


name: an aromatic aldehyde + H2O + O2 = an aromatic carboxylate + H(+) + H2O2


name: 1'-hydroxy-demethylspheroidene + AH2 => 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene + A


name: RNA polymerase II CTD heptapeptide repeat Y1 kinase activity


name: hexadecanedioyl-CoA + O2 => (2E)-hexadecenedioyl-CoA + H2O2


name: a (3E)-enoyl-CoA + H2O => a 4-saturated-(3S)-3-hydroxyacyl-CoA


name: myricetin + S-adenosyl-L-methionine = H(+) + laricitrin + S-adenosyl-L-homocysteine


name: a 2'-deoxycytidine in double-stranded DNA + H(+) + H2O <=> a 2'-deoxyuridine in double-stranded DNA + NH4(+)


name: MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) (Schizosaccharomyces pombe)


name: AMP + benzoyl-CoA + diphosphate => ATP + benzoate + CoA


name: crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) (Gallus gallus)


name: ADP + H(+) + N(pros)-phospho-L-histidyl-[protein] => ATP + L-histidyl-[protein]


name: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) => ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate


name: KIT binds type I TKIs (Xenopus tropicalis)


name: PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: Formation of the Spliceosomal E complex (Sus scrofa)


name: hydroxyclavatol => H2O + o-quinone methide


name: TFAP2B homodimer binds YEATS4 (Drosophila melanogaster)


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Homo sapiens)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Saccharomyces cerevisiae)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Xenopus tropicalis)


name: ATP + beta-D-fructose => ADP + beta-D-fructose 1-phosphate + H(+)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Sus scrofa)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Homo sapiens)


name: Neuropeptide S receptor binds neuropeptide S (Mus musculus)


name: cytidine 2'-phosphate + H(+) => 2',3'-cyclophospho-CMP + H2O


name: deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Xenopus tropicalis)


name: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + oxidized dithiothreitol = 1,4-dithiothreitol + 2,3-epoxyphylloquinone


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-hexadecyl-sn-glycero-3-phosphocholine => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Schizosaccharomyces pombe)


name: (2S)-2-amino-2'-deoxyadenylo-succinate => dZMP + fumarate


name: p-MAPK2/3 phosphorylates HSP27 (Homo sapiens)


name: GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol (Homo sapiens)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Rattus norvegicus)


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Xenopus tropicalis)


name: an alpha-L-fucoside + H2O <=> an alcohol + L-fucose


name: holo-[peptidyl-carrier protein] + L-glutamyl-5'-AMP = AMP + H(+) + L-glutamyl-[peptidyl-carrier protein]


name: (R)-carnitine + tetradecanoyl-CoA = CoA + O-tetradecanoyl-(R)-carnitine


name: 2 Fe(III)-[cytochrome c] + H2O + lupanine = 17-hydroxylupanine + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: "lupanine 17-hydroxylase (cytochrome c)"


name: CDC42:GTP:FMNL2 binds Profilin:G-actin (Bos taurus)


name: acetyl-CoA + N-terminal L-methionyl-L-valyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-valyl-[protein]


name: CTP + pseudaminate = CMP-pseudaminate + diphosphate


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine


name: cAMP activates EPAC1 (Drosophila melanogaster)


name: ISGylation of PKR (Caenorhabditis elegans)


name: CDP-DAG is converted to PI by CDIPT (Xenopus tropicalis)


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-jasmololone = CoA + jasmolin II


name: O-acetyl-15alpha-stemmadenine + O2 => H2O2 + precondylocarpine acetate


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Bos taurus)


name: Secretion of transmembrane collagens (Bos taurus)


name: AH2 + D-ribulose 5-phosphate <=> 1-deoxy-D-xylulose 5-phosphate + A + H2O


name: ATP + H2O + kainate(in) => ADP + H(+) + kainate(out) + phosphate


name: diacetyl reductase ((R)-acetoin forming) activity


name: Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)


name: chloride(out) + L-isoleucine(out) + 2 Na(+)(out) = chloride(in) + L-isoleucine(in) + 2 Na(+)(in)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH = (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: homoserine transmembrane transporter activity


name: AKT phosphorylates caspase-9 (Gallus gallus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Danio rerio)


name: adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Bos taurus)


name: CHD1 translation is negatively regulated by miR-26A and B (Homo sapiens)


name: PDE3A hydrolyses cAMP to AMP (Homo sapiens)


name: Formation of clathrin coated vesicle (Gallus gallus)


name: MMACHC dealkylates RCbl (Canis familiaris)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Schizosaccharomyces pombe)


name: acetyl-CoA + 7 H(+) + 7 malonyl-CoA => 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + 7 CO2 + 8 CoA + 2 H2O


name: ATP + O-alkylglycerone => 1-O-alkylglycerone 3-phosphate + ADP + H(+)


name: voltage-gated sodium channel activity involved in cardiac muscle cell action potential


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Schizosaccharomyces pombe)


name: Enhanced autophagosome formation (Homo sapiens)


name: acetyl-CoA + oxaloacetate => (3S)-citryl-CoA


name: SUMOylation of PIAS4 with SUMO1 (Bos taurus)


name: PKC alpha interacts with and phosphorylates KIT (Mus musculus)


name: NADP(+) + prostaglandin F1 => H(+) + NADPH + prostaglandin E1


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = A + H2O + prostaglandin H2


name: IRE1 dimer autophosphorylates (Rattus norvegicus)


name: 3-(3-methylsulfanyl)propylmalate <=> 2-(2-methylsulfanyl)propylmaleate + H2O


name: ECHS1 hydrates methacrylyl-CoA (Mus musculus)


name: Caspase-mediated cleavage of Z0-2 (Homo sapiens)


name: Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it (Bos taurus)


name: ATP + beta-alanine + L-lysine <=> ADP + beta-alanyl-L-lysine + H(+) + phosphate


name: ABHD6,12 hydrolyse 3AG (Caenorhabditis elegans)


name: Proteosome-mediated degradation of APOBEC3G (Homo sapiens)


name: hydroquinone + O2 = (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate + H(+)


name: 4-acetoxyphenol + H2O <=> acetate + H(+) + hydroquinone


name: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA => 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA


name: PRKCI phosphorylates NFE2L2 (Canis familiaris)


name: p38 MAPK activation by VEGFR (Drosophila melanogaster)


name: 1-hexadecanoylglycerone 3-phosphate + octadecan-1-ol => 1-O-octadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: TFAP2A in complex with DEK binds the APOE gene promoter (Homo sapiens)


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Homo sapiens)


name: ENPP7 hydrolyzes sphingomyelin (Schizosaccharomyces pombe)


name: G-protein alpha subunit is inactivated (Xenopus tropicalis)


name: angiotensin-(1-7) + L-phenylalanyl-L-histidine => angiotensin-(1-9) + H2O


name: (2R,3S)-homoisocitrate <=> cis-homoaconitate + H2O


name: (S)-2-chloropropanoate + H2O <=> (R)-lactate + chloride + H(+)


name: (2E,6E)-farnesyl diphosphate + L-cysteinyl-[protein] = diphosphate + S-(2E,6E)-farnesyl-L-cysteinyl-[protein]


name: N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-glucuronate <=> [hyaluronan](n+1) + H(+) + UDP


name: ITCH polyubiquitinates MLKL at K50 (Homo sapiens)


name: Hydrolysis of phosphatidylcholine (Gallus gallus)


name: NAD(+) + pyridoxal <=> 4-pyridoxolactone + H(+) + NADH


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-mannosylinositol-1-phosphoceramide => a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-alpha-mannosylinositol-1-phosphoceramide


name: JMY, TTC5 and EP300 bind (Canis familiaris)


name: urokinase plasminogen activator receptor activity


name: Beta-catenin translocates to the nucleus (Rattus norvegicus)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Bos taurus)


name: [LarE protein]-L-cysteine + ATP + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide <=> [LarE protein]-dehydroalanine + AMP + diphosphate + H(+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)


name: Activated FGFR4 binds SHC1 (Gallus gallus)


name: PTPN11 binds p-Y759-IL6ST (Xenopus tropicalis)


name: P2Y5 receptor can bind to LPA (Caenorhabditis elegans)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (R)-axinyssene + diphosphate


name: 8-oxo-GTP + H2O <=> 8-oxo-GDP + H(+) + phosphate


name: an aromatic aldehyde + H(+) + NADH => an aromatic primary alcohol + NAD(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate <=> (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate