name: Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Canis familiaris)


name: glutarate(in) + glycocholate(out) <=> glutarate(out) + glycocholate(in)


name: a (3R)-3-hydroxyacyl-CoA + NAD(+) => a 3-oxoacyl-CoA + H(+) + NADH


name: Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex (Gallus gallus)


name: H(+) + NADH + uridine(47) in tRNA => 5,6-dihydrouridine(47) in tRNA + NAD(+)


name: H2O + N(2)-(3-hydroxy-3-methylhexanoyl)-L-glutaminate <=> 3-hydroxy-3-methylhexanoate + L-glutamine


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Rattus norvegicus)


name: factor Va + factor Xa -> Va:Xa complex (prothrombinase) (Canis familiaris)


name: ARL6:GTP and the BBSome bind ciliary cargo (Rattus norvegicus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + hexadecanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-hexadecanoyl-sn-glycerol + CoA


name: kainate receptor binds glutamate (Drosophila melanogaster)


name: 10-deacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C


name: 3-hydroxyphenylacetate + H(+) + NADPH + O2 <=> H2O + homogentisate + NADP(+)


name: 4-hydroxybenzoate + ATP + H(+) <=> 4-hydroxybenzoyl-5'-AMP + diphosphate


name: RNA exonuclease activity, producing 5'-phosphomonoesters


name: MTMR4 binds phosphorylated SMAD2/3 (Xenopus tropicalis)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Bos taurus)


name: TRIM21 ubiquitinates SQSTM1 (Xenopus tropicalis)


name: Factor I inactivates plasma Factor H-bound C3b (Xenopus tropicalis)


name: dodecanedioyl-CoA + O2 = (2E)-dodecenedioyl-CoA + H2O2


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Danio rerio)


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Homo sapiens)


name: GLTP transports GSL from plasma membrane to ER membrane (Xenopus tropicalis)


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + H(+) => 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + H2O


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Xenopus tropicalis)


name: SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors (Homo sapiens)


name: ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Sus scrofa)


name: (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + NADPH <=> (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + NADP(+)


name: jasmonate + S-adenosyl-L-methionine = methyl (-)-jasmonate + S-adenosyl-L-homocysteine


name: 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+)


name: H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu) => L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein]


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Xenopus tropicalis)


name: Duplex siRNA is loaded into Argonaute (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Sus scrofa)


name: (S)-tetrahydropapaverine + S-adenosyl-L-methionine = (S)-N-methyltetrahydropapaverine + H(+) + S-adenosyl-L-homocysteine


name: BPI binds LPS on the bacterial surface (Xenopus tropicalis)


name: 2 H(+) + H2O + thiocyanate <=> carbonyl sulfide + NH4(+)


name: 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 <=> 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: ECHS1 hydrates methacrylyl-CoA (Xenopus tropicalis)


name: MASTL (GWL) phosphorylates ARPP19 (Bos taurus)


name: H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] = N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate


name: Cholate is translocated from the peroxisomal matrix to the cytosol (Homo sapiens)


name: ACSF3 ligates CoA-SH to VLCFA (Rattus norvegicus)


name: histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen (Canis familiaris)


name: butanoate(in) + dehydroepiandrosterone 3-sulfate(out) => butanoate(out) + dehydroepiandrosterone 3-sulfate(in)


name: HDAC1:2-containing complex deacetylate histones (Bos taurus)


name: ARFRP1 recruits ARL1 to the TGN (Drosophila melanogaster)


name: p-S407,Y641-STAT6 is dimerized (Xenopus tropicalis)


name: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] <=> a 2-hydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 = 4beta-methylzymosterol-4alpha-carboxylate + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: AcK-NFE2L2-dependent GCLM gene expression (Homo sapiens)


name: CDC42 translocates to the endoplasmic reticulum membrane (Danio rerio)


name: NR1H2,3 binds the EEPD1 gene (Homo sapiens)


name: p-STAT3 dissociates from IL24:IL22RA1:p‑JAK1:IL20RB:p‑STAT3 (Mus musculus)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Xenopus tropicalis)


name: 6-oxocampestanol + O2 + reduced [NADPH--hemoprotein reductase] => cathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + glycyl-tRNA(Gly) => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-Gly)-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + tRNA(Gly)


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Canis familiaris)


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Bos taurus)


name: ESTG binds ESR1:chaperone complex (Xenopus tropicalis)


name: glutaryl-CoA + H2O <=> CoA + glutarate + H(+)


name: Transport of antigen loaded MHC II molecules to surface (Canis familiaris)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Homo sapiens)


name: SARS-CoV-1 nsp1 binds to 40S ribosomal subunit (Homo sapiens)


name: 2-methoxybenzoate + ATP + H(+) + NADPH => 2-methoxybenzaldehyde + AMP + diphosphate + NADP(+)


name: OTULIN,USP5 cleaves UBB yielding ubiquitin (Canis familiaris)


name: Defective MUTYH mutants do not cleave adenine mispaired with 8-oxoguanine (Homo sapiens)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Drosophila melanogaster)


name: (9Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: Binding of STAT1 to p-IFNGR1 (Canis familiaris)


name: TLR4-induced ripoptosome assembly (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (R)-cembrene A + diphosphate


name: (2S)-2-methylbutanenitrile + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-2-methylbutanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AKR1A1 reduces D-glucuronate to L-gulonate (Dictyostelium discoideum)


name: Caspase-7 translocates to the nucleus (Rattus norvegicus)


name: Active G alpha (q) binds RGS proteins (Saccharomyces cerevisiae)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) => (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH


name: (2E)-butenoyl-CoA + AH2 => A + butanoyl-CoA


name: RHOA binds effectors at the plasma membrane (Canis familiaris)


name: HSF1 acetylation at Lys80 (Rattus norvegicus)


name: adenosine(58) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine


name: H2O2 + prosolanapyrone III => O2 + prosolanapyrone II


name: (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+) => 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Rattus norvegicus)


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Homo sapiens)


name: SLC2A5 transports fructose from extracellular region to cytosol (Mus musculus)


name: (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O => (9Z,12Z)-octadecadienoate + AH2 + O2


name: SHC1 in the RET complex is phosphorylated (Bos taurus)


name: Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Xenopus tropicalis)


name: MIB2 ubiquitinates CYLD at K338, K530 (Rattus norvegicus)


name: MICAL1 produces NADP+, H2O2 (Xenopus tropicalis)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Mus musculus)


name: H(+) + NADH + O2 + salicylate = 2,3-dihydroxybenzoate + H2O + NAD(+)


name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Danio rerio)


name: MTMR8 binds MTMR9 (Drosophila melanogaster)


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Canis familiaris)


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Sus scrofa)


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Bos taurus)


name: 1,4-dihydroxy-2-naphthoate + all-trans-hexaprenyl diphosphate + H(+) => 2-demethylmenaquinol-6 + CO2 + diphosphate


name: PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) (Saccharomyces cerevisiae)


name: Mcm2-7 is phosphorylated by DDK (Bos taurus)


name: ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Mus musculus)


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-acyl-2-[(7Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (3R)-hydroxy-4-methylpentanoyl-[ACP] + NADP(+) => 4-methyl-3-oxopentanoyl-[ACP] + H(+) + NADPH


name: Interaction of Tie2 with Ang2 (Danio rerio)


name: O2 + tetradecanoate => (2R)-2-hydroperoxytetradecanoate


name: Dissociation of  transcript with 5'-GMP from GT (Schizosaccharomyces pombe)


name: Salvage - Sepiapterin is reduced to BH2 (Sus scrofa)


name: fluoroacetaldehyde + H2O + NAD(+) <=> fluoroacetate + 2 H(+) + NADH


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-hexacosanoylsphinganine = a 1,2-diacyl-sn-glycerol + N-(hexacosanoyl)-sphinganine-1-(1D-myo-inositol)


name: DCAKD phosphorylates DP-CoA (Drosophila melanogaster)


name: IL21 receptor STAT binding (Rattus norvegicus)


name: Formation of NR-NCOR Corepressor Complex (Bos taurus)


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Rattus norvegicus)


name: VMAT1/2 can mediate the transport of biogenic amines (Gallus gallus)


name: AH2 + 2 N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline => A + 2 N(delta)-hydroxy-N(omega)-methyl-L-citrulline + 2 nitric oxide


name: USP34 deubiquitinates AXIN1,AXIN2 (Sus scrofa)


name: 5beta-dihydrotestosterone + H(+) + NADPH => 5beta-androstane-3alpha,17beta-diol + NADP(+)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Sus scrofa)


name: acetyl-CoA + N-terminal L-methionyl-L-alanyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-alanyl-[protein]


name: adenosine 5'-phosphosulfate + diphosphate => ATP + H(+) + sulfate


name: 2-deoxy-D-ribose 5-phosphate + hypoxanthine => dIMP + H2O


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Canis familiaris)


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Canis familiaris)


name: Spherical HDL binds membrane-associated free cholesterol and phospholipids (Sus scrofa)


name: D-serine + H2O + NAD(+) <=> 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: (9Z)-octadecenoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol => 1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Sus scrofa)


name: Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane (Homo sapiens)


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Caenorhabditis elegans)


name: TFAP2C homodimer binds MYC and KDM5B (Canis familiaris)


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Xenopus tropicalis)


name: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH


name: Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity (Homo sapiens)


name: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] <=> an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FN3K phosphorylates ketosamines (Homo sapiens)


name: nucleobase:monoatomic cation symporter activity


name: H2O + L-phenylalanine + NAD(+) => 3-phenylpyruvate + H(+) + NADH + NH4(+)


name: maltose + H2O => 2 D-glucose (maltase-glucoamylase) (Bos taurus)


name: ganglioside GM1 (d18:1(4E)/18:0) + H2O = D-galactose + ganglioside GM2 (d18:1(4E)/18:0)


name: B4GALT5/6 transfer Gal to GlcCer (Xenopus tropicalis)


name: demethylphylloquinone + H(+) + NADPH => demethylphylloquinol + NADP(+)


name: 5,6-dihydrouracil + H2O <=> 3-(carbamoylamino)propanoate + H(+)


name: a carboxylate + an alcohol + H(+) => a carboxylic ester + H2O


name: N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP


name: IL37(?-218) translocates from the cytosol to the nucleus (Homo sapiens)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)


name: [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose = alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: H(+) + homogentisate + phytyl diphosphate => 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Rattus norvegicus)


name: CETP-mediated lipid exchange: spherical HDL gains triacylglycerol (Gallus gallus)


name: A + all-trans-zeta-carotene => AH2 + all-trans-neurosporene


name: PPP5C dephosphorylates TP53BP1 (Homo sapiens)


name: UDP-alpha-D-glucose(out) + UMP(in) => UDP-alpha-D-glucose(in) + UMP(out)


name: Formation of NR-NCOR Corepressor Complex (Xenopus tropicalis)


name: (R)-vicianin + H2O <=> mandelonitrile + vicianose


name: GLI3R translocates to the nucleus (Bos taurus)


name: Caspase-8 and FLIP(L) processing at DISC (Rattus norvegicus)


name: a fatty acyl-CoA + L-seryl-[protein] => CoA + O-fatty acyl-L-seryl-[protein]


name: Reorientation of dolichyl phosphate D-mannose in the endoplasmic reticulum membrane (Homo sapiens)


name: Activated PLC gamma dissociates from the PDGF receptor (Gallus gallus)


name: ABL1 phosphorylates RAD52 (Gallus gallus)


name: Proton-coupled di- and tri-peptide cotransport (Danio rerio)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Rattus norvegicus)


name: (3S)-3-hydroxyadipyl-CoA => (E)-2,3-didehydroadipoyl-CoA + H2O


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Rattus norvegicus)


name: D-apionolactone + H2O <=> D-apionate + H(+)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + trimethylamine N-oxide => 2 Fe(III)-[cytochrome c] + H2O + trimethylamine


name: dATP + pyruvate = dADP + H(+) + phosphoenolpyruvate


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)


name: EPH:EFN dimers tetramerise (Canis familiaris)


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Homo sapiens)


name: STAT3 binds activated MET receptor (Xenopus tropicalis)


name: 5,6-dihydrouridine(20a) in tRNA + NADP(+) => H(+) + NADPH + uridine(20a) in tRNA


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Xenopus tropicalis)


name: MLKL binds PDCD6IP and SDCBP (Mus musculus)


name: D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ (Bos taurus)


name: fumarate(in) + L-aspartate(out) <=> fumarate(out) + L-aspartate(in)


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Sus scrofa)


name: (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase] = (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA = 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate


name: calcium-dependent protein kinase inhibitor activity


name: Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Homo sapiens)


name: TFIIF-class transcription factor complex binding


name: Formation of RAD50:MRE11 complex (Bos taurus)


name: NAA translocates from mitochondrial matrix to cytosol (Homo sapiens)


name: TCN2:RCbl is degraded to release RCbl (Homo sapiens)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Drosophila melanogaster)


name: Dehalogenation of carbon tetrachloride to form a free radical (Caenorhabditis elegans)


name: all-trans-retinol + NAD(+) = all-trans-retinal + H(+) + NADH


name: 3'-phosphoadenylyl sulfate + quercetin 3-sulfate <=> adenosine 3',5'-bisphosphate + H(+) + quercetin 3,4'-bissulfate


name: 4-methylphenol + H2O + 4 oxidized [azurin] <=> 4-hydroxybenzaldehyde + 4 H(+) + 4 reduced [azurin]


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Canis familiaris)


name: Autophosphorylation of PKC-theta (Bos taurus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + D-galactose => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H2O


name: adenosine 3',5'-bisphosphate + H(+) + holo-[D-alanyl-carrier protein] => apo-[D-alanyl-carrier protein] + CoA


name: LINC01139 facilitates PTK6 autophosphorylation (Sus scrofa)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Schizosaccharomyces pombe)


name: (9Z)-octadecenoyl-CoA + FAD + H(+) => (2E,9Z)-octadecadienoyl-CoA + FADH2


name: (2E,6E)-farnesyl diphosphate <=> (+)-delta-selinene + diphosphate


name: SEC22B, CALR, STX4, TAP and TAPBP bind (Mus musculus)


name: (2E,6E)-farnesyl diphosphate => diphosphate + guaia-4,6-diene


name: CA4:Zn2+ hydrates CO2 to HCO3- (Drosophila melanogaster)


name: TNF-alpha inhibitors bind to TNF(1-233) trimer (Homo sapiens)


name: Migfilin interacts with VASP (Gallus gallus)


name: Keratin tetramers bind to form unit length filaments (Homo sapiens)


name: 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity


name: TGFBR1 is recruited to tight junctions by PARD6A (Homo sapiens)


name: AGO2 cleaves passenger strand of duplex siRNA (Xenopus tropicalis)


name: (7R,8S)-8-amino-7-(carboxyamino)nonanoate + ATP => (4R,5S)-dethiobiotin + ADP + H(+) + phosphate


name: DHDB is methylated to MHDB by COQ3 (Homo sapiens)


name: chloride(in) + oxalate(out) => chloride(out) + oxalate(in)


name: 2,2-dialkylglycine + H(+) + pyruvate => CO2 + dialkyl ketone + L-alanine


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Drosophila melanogaster)


name: beta-D-galactosyl-(1<->1')-N-hexadecanoylsphingosine + H2O <=> beta-D-galactose + N-hexadecanoylsphing-4-enine


name: Phosphorylation of extracellular domain KIT mutants (Homo sapiens)


name: NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Sus scrofa)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Canis familiaris)


name: PLK1 phosphorylates OPTN (Canis familiaris)


name: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity


name: 2-aminomuconate 6-semialdehyde => 2-aminophenol + O2


name: (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: peptide-methionine (R)-S-oxide reductase activity


name: butane-1-sulfonate + FMNH2 + O2 = butanal + FMN + 2 H(+) + H2O + sulfite


name: NT5C2 tetramer dephosphorylates RBV-MP (Gallus gallus)


name: glyoxylate + L-asparagine = 2-oxosuccinamate + glycine


name: CDK2:CCNA phosphorylates TERF2 (Canis familiaris)


name: adenosine + H2O + 2 O2 <=> 9-riburonosyladenine + H(+) + 2 H2O2


name: dehydroepiandrosterone 3-sulfate(out) <=> dehydroepiandrosterone 3-sulfate(in)


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Mus musculus)


name: Cleaved KMT2A dimers translocate to the nucleus (Gallus gallus)


name: EGF-TM7 receptors bind chondroitin sulphate (Canis familiaris)


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: acetoin + CoA + NAD(+) <=> acetaldehyde + acetyl-CoA + H(+) + NADH


name: LGI3 binds ADAM22,23,synatxin1 (Rattus norvegicus)


name: 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphocholine + CoA => (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine


name: IL12B translocates from the cytosol to the extracellular region (Homo sapiens)


name: Tyrosine is monoiodinated (Dictyostelium discoideum)


name: H(+) + NADH + orotate => (S)-dihydroorotate + NAD(+)


name: erythritol + NADP(+) <=> D-erythrose + H(+) + NADPH


name: Formation of the pre-incision complex in GG-NER (Homo sapiens)


name: 2 3beta-hydroxy-beta-cyclocitral + crocetin dialdehyde => all-trans-zeaxanthin + 2 O2


name: 24-methylidenelophenol + S-adenosyl-L-methionine = (Z)-24-ethylidenelophenol + H(+) + S-adenosyl-L-homocysteine


name: ent-cassa-12,15-dien-2beta-ol + O2 + reduced [NADPH--hemoprotein reductase] => ent-cassa-12,15-dien-2beta,3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PAK1 phosphorylates myosin phosphatase (Canis familiaris)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO2 + CoA


name: H(+) + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate => L-glutamate + O-phospho-L-serine


name: chloride + FADH2 + L-tryptophan + O2 => 5-chloro-L-tryptophan + FAD + 2 H2O


name: ATP + xylitol <=> ADP + H(+) + xylitol 5-phosphate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acylglycerol => a 1-acyl-sn-glycero-3-phosphoethanolamine + a 2,3-diacyl-sn-glycerol


name: H(+)(in) + lactose(in) <=> H(+)(out) + lactose(out)


name: 1-octadecanoyl-2-nonanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + nonanoate


name: L-glutamine + pyruvate <=> 2-oxoglutaramate + L-alanine


name: PAK1-3 autophosphorylates (Rattus norvegicus)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Xenopus tropicalis)


name: hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate


name: ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Caenorhabditis elegans)


name: NOTCH1 associates with negative regulators NUMB and ITCH (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate <=> (1S,5S,6R)-alpha-bergamotene + diphosphate


name: Activated FGFR3:p-FRS bind to PPTN11 (Bos taurus)


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Gallus gallus)


name: SUMOylation of TDG with SUMO2,3 (Xenopus tropicalis)


name: (3R)-3-hydroxydecanoyl-CoA + NAD(+) => 3-oxodecanoyl-CoA + H(+) + NADH


name: ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Mus musculus)


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Xenopus tropicalis)


name: MMP14 (MT1-MMP) binds TIMP2 (Drosophila melanogaster)


name: WNT5A-FZD4 recruits DVL2 (Canis familiaris)


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Sus scrofa)


name: acetyl-CoA + 8 H(+) + holo-[ACP] + 8 malonyl-CoA = 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + 8 CO2 + 9 CoA + 2 H2O


name: SULTs transfer (SO4)2- group to 27HCHOL (Sus scrofa)


name: 1-O-(trans-sinapoyl)-beta-D-glucose + anthocyanin A8 = anthocyanin A11 + D-glucose


name: PEX7 binds cargo proteins containing PTS2 (Rattus norvegicus)


name: enterobactin + UDP-alpha-D-glucose => monoglucosyl-enterobactin + UDP


name: Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Canis familiaris)


name: STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Sus scrofa)


name: NEK6 and NEK7 phosphorylate EML4 (Gallus gallus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Xenopus tropicalis)


name: ROCK activation by RHO (Drosophila melanogaster)


name: USP7 deubiquitinates MDM2 (Rattus norvegicus)


name: a quinone + H2O + nitrite => a quinol + nitrate


name: a jasmonate + an L-alpha-amino acid + ATP => a jasmonyl-L-amino acid + AMP + diphosphate + H(+)


name: 2 ATP + GTP <=> 3',3',3'-cAAG + 3 diphosphate


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Sus scrofa)


name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Drosophila melanogaster)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Xenopus tropicalis)


name: [HPr protein]-L-serine + ATP = [HPr protein]-O-phospho-L-serine + ADP + H(+)


name: DVL2 binds phosphorylated WWTR1 (TAZ) (Bos taurus)


name: high mobility group box 1 receptor activity


name: 17alpha-estradiol + NAD(+) => estrone + H(+) + NADH


name: H2O + O2 + pyridoxamine => H2O2 + NH4(+) + pyridoxal


name: 17alpha-estradiol + UDP-alpha-D-glucuronate = 17alpha-estradiol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: [(R)-3-hydroxyalkanoate](n) + a (3R)-3-hydroxyacyl-CoA = [(R)-3-hydroxyalkanoate](n+1) + CoA


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + syringate => 3-O-methylgallate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: NLK translocates to nucleus (Canis familiaris)


name: dimethyl sulfoxide + H(+) + NADH + O2 => dimethyl sulfone + H2O + NAD(+)


name: HRSP12 deaminates 2AA to 2OBUTA (Bos taurus)


name: RHOV binds effectors at the plasma membrane (Canis familiaris)


name: L protein acts as a cap N7 methyltransferase to modify RSV mRNAs (Homo sapiens)


name: 3 NADP(+) + phytyl diphosphate <=> geranylgeranyl diphosphate + 3 H(+) + 3 NADPH


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Gallus gallus)


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Sus scrofa)


name: 4-(trimethylamino)butanoate + ATP + CoA => 4-(trimethylamino)butanoyl-CoA + AMP + diphosphate


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O <=> 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine


name: cholate + deoxycholoyl-CoA => choloyl-CoA + deoxycholate


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Saccharomyces cerevisiae)


name: Recruitment of Gads to LAT (Canis familiaris)


name: (E)-cinnamaldehyde + CoA + NADP(+) <=> (E)-cinnamoyl-CoA + H(+) + NADPH


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3-O-beta-D-glucoside <=> an anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] + CoA + H(+)


name: 8 H(+) + holo-[ACP] + 8 malonyl-CoA = atrochrysone carboxyl-[ACP] + 8 CO2 + 8 CoA + 2 H2O


name: Phosphorylated HPO dimer phosphorylates TH (Drosophila melanogaster)


name: SHOC2 M173I disrupts the SHOC2:MRAS:PP1 complex (Homo sapiens)


name: a primary alcohol + 2 oxidized [azurin] <=> an aldehyde + 2 H(+) + 2 reduced [azurin]


name: myo-inositol + UDP-alpha-D-galactose => alpha-D-galactosyl-(1->3)-1D-myo-inositol + H(+) + UDP


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Bos taurus)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Mus musculus)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate = adenosine 5'-tetraphosphate + AMP + 2 H(+)


name: 2 H2O + 2 L-dopaquinone => 2 L-dopa + O2


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Gallus gallus)


name: carboxymethoxysuccinate => fumarate + glycolate


name: [mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + AH2 + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + A + H(+) + L-methionine


name: Retromer associates with WLS (Sus scrofa)


name: 3-hydroxyisovaleryl-CoA => 3-methyl-(2E)-butenoyl-CoA + H2O


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Drosophila melanogaster)


name: H2O + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD(+) = (S)-2,3-diaminopropanoate + 2-oxoglutarate + H(+) + NADH


name: a dicarboxylate(out) + estrone 3-sulfate(in) => a dicarboxylate(in) + estrone 3-sulfate(out)


name: SUMOylation of TOPORS with SUMO1 (Rattus norvegicus)


name: A + a 3-oxo-5alpha-steroid <=> a 3-oxo-Delta(4)-steroid + AH2


name: SLCO3A1 isoform 1 has abroad substrate specificity (Mus musculus)


name: 2-oxoglutarate + L-tyrosine = 3-(4-hydroxyphenyl)pyruvate + L-glutamate


name: [(1->4)-beta-D-glucosyl](n) + phosphate = [(1->4)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: BDNF gene expression is stimulated by NPAS4:ARNT2 (Homo sapiens)


name: Formation of allysine by LOX (Danio rerio)


name: MIA2 and MIA3 dissociate from procollagen VII vesicle (Mus musculus)


name: Exocytosis of azurophil granule membrane proteins (Plasmodium falciparum)


name: NFkB complex translocates from the cytosol to the nucleus (Sus scrofa)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Rattus norvegicus)


name: STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Mus musculus)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Sus scrofa)


name: De novo formation of eIF2:GTP (Homo sapiens)


name: Melanospin is stimulated by light (Drosophila melanogaster)


name: (3S)-hydroxydecanedioyl-CoA + NAD(+) = 3-oxodecanedioyl-CoA + H(+) + NADH


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Saccharomyces cerevisiae)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Sus scrofa)


name: 5,6,7,8-tetrahydromethanopterin + H(+) + N-formylmethanofuran <=> methanofuran + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: allose transmembrane transporter activity


name: H2O + 2 oxidized [azurin] + tyramine <=> (4-hydroxyphenyl)acetaldehyde + 2 H(+) + NH4(+) + 2 reduced [azurin]


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Sus scrofa)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Schizosaccharomyces pombe)


name: 3-phenylpyruvate + L-aspartate => L-phenylalanine + oxaloacetate


name: dimethyl sulfoxide + H(+) + NADH + O2 <=> dimethyl sulfone + H2O + NAD(+)


name: TXLNA (IL14) binds syntaxin3 (Rattus norvegicus)


name: (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + H(+) + 2 holo-[ACP] => 2 (3R)-hydroxydecanoyl-[ACP] + H2O


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate => (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: USP33 deubiquitinates CCP110,ARRB (Drosophila melanogaster)


name: L-glutamate + O-phospho-L-serine = H(+) + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Canis familiaris)


name: Syndecan-1 binds fibronectin (Homo sapiens)


name: Alpha-defensins form biologically active dimers (Rattus norvegicus)


name: p75NTR and RHOA-GDI interact (Rattus norvegicus)


name: TPX2 binds AURKA at centrosomes (Xenopus tropicalis)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Rattus norvegicus)


name: 2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate <=> 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK (Homo sapiens)


name: CD38 hydrolyses NAD+ to NAM and ADP-ribose (Canis familiaris)


name: (3R)-3-amino-3-phenylpropanoyl-CoA + baccatin III = 3'-N-debenzoyl-2'-deoxytaxol + CoA


name: STIM1 oligomerizes (Caenorhabditis elegans)


name: Cdc6 protein is phosphorylated by CDK (Gallus gallus)


name: Collagen type XII degradation by MMP12 (Caenorhabditis elegans)


name: 2 Fe(III)-[cytochrome b1] + formate = CO2 + 2 Fe(II)-[cytochrome b1] + H(+)


name: 7-dehydrodesmosterol + H(+) + NADPH <=> desmosterol + NADP(+)


name: CREB3L3 translocates from the cytosol to the nucleus (Danio rerio)


name: (3S)-hydroxy-3-methylglutaryl-CoA + H2O <=> 3-hydroxy-3-methylglutarate + CoA + H(+)


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Bos taurus)


name: ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)


name: (4S)-limonene + A + H2O <=> (4S)-perillyl alcohol + AH2


name: CTDNEP1:CNEP1R1 dephosphorylates LPIN (Sus scrofa)


name: cytidine(60) in tRNA(Asp) + S-adenosyl-L-methionine => 5-methylcytidine(60) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: (2E,6E)-farnesol + ATP = (2E,6E)-farnesyl phosphate + ADP + H(+)


name: Interaction of Tie2 and Shp2 (Mus musculus)


name: L-glutamine(out) + L-valine(in) + Na(+)(in) => L-glutamine(in) + L-valine(out) + Na(+)(out)


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Danio rerio)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Bos taurus)


name: Monoubiquitination of FANCD2:FANCI (Rattus norvegicus)


name: AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it (Canis familiaris)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Mus musculus)


name: NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Gallus gallus)


name: dAMP + H2O = 2'-deoxyadenosine + phosphate


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Gallus gallus)


name: H(+) + trimethylamine N-oxide <=> dimethylamine + formaldehyde


name: p-STAT5 dissociates from the receptor complex (Rattus norvegicus)


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Schizosaccharomyces pombe)


name: [phosphate](n) + ADP => [phosphate](n+1) + AMP


name: 1-octadecanoylglycerol + H2O = glycerol + H(+) + octadecanoate


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Canis familiaris)


name: Processing of SCF isoform 1 (Sus scrofa)


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + H2O = 1D-myo-inositol 2,3,4,5-tetrakisphosphate + phosphate


name: ADP + H(+) + L-glutamine(in) + phosphate => ATP + H2O + L-glutamine(out)


name: aminotriazole transmembrane transporter activity


name: Collagen XI cross-links with collagen II (Mus musculus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Xenopus tropicalis)


name: ATP + H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out) = ADP + H(+) + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) + phosphate


name: factor V -> factor Va + factor V activation peptide (Sus scrofa)


name: RUNX1:CBFB binds CREBBP (Caenorhabditis elegans)


name: isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Sus scrofa)


name: G-protein coupled bile acid receptor binds lithocholic acid (Mus musculus)


name: PIP3 recruits PDPK1 to the membrane (Canis familiaris)


name: USP33 deubiquitinates CCP110,ARRB (Rattus norvegicus)


name: SAR1 Activation And Membrane Binding (Mus musculus)


name: 1-butyrylglycerol + H2O => butanoate + glycerol + H(+)


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Gallus gallus)


name: 2,6-dichlorohydroquinone + chloride + glutathione disulfide + H(+) <=> 2,3,6-trichlorohydroquinone + 2 glutathione


name: Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Sus scrofa)


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Homo sapiens)


name: gibberellin A9 carboxyl methyltransferase activity


name: (25S)-Delta7-dafachronate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => 5alpha-cholest-7-en-3-one + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: S-methyl-5-thio-D-ribulose 1-phosphate = S-methyl-1-thio-D-xylulose 5-phosphate


name: Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Sus scrofa)


name: Phosphorylated KIT mutants bind PI3K (Homo sapiens)


name: CDC42 and PIP2 bind WASL, activating it (Drosophila melanogaster)


name: AVPR1A,B bind desmopressin (Homo sapiens)


name: SCF-FBXL7 ubiquitinates AURKA (Dictyostelium discoideum)


name: 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine <=> 1-tetradecanoyl-sn-glycero-2,3-cyclic phosphate + ethanolamine


name: 5-hydroxykynurenamine + CO2 = 5-hydroxy-L-kynurenine + H(+)


name: Formation of RAD52 heptameric ring structure complexes (Dictyostelium discoideum)


name: PRICKLE1 is degraded by the proteasome (Bos taurus)


name: (5S)-5-amino-3-oxohexanoate + acetyl-CoA <=> (3S)-3-aminobutanoyl-CoA + acetoacetate


name: precorrin-6A synthase (deacetylating) activity


name: AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)


name: glycolaldehyde + H2O + NAD(+) => glycolate + 2 H(+) + NADH


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Sus scrofa)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Bos taurus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(out) + ADP + H(+) + phosphate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(in) + ATP + H2O


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Caenorhabditis elegans)


name: a UDP-monosaccharide + diphosphate => a monosaccharide 1-phosphate + H(+) + UTP


name: SUMOylation of PCNA with SUMO1 (Schizosaccharomyces pombe)


name: 6-oxocampestanol + O2 + reduced [NADPH--hemoprotein reductase] <=> cathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: cAMP induces dissociation of inactive PKA tetramers (Homo sapiens)


name: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H2O <=> L-threonyl-[protein] + N-acetyl-D-glucosamine


name: ATPase-coupled ectoine transmembrane transporter activity


name: ATP + H2O + L-ectoine(out) = ADP + H(+) + L-ectoine(in) + phosphate


name: dTDP-alpha-D-mycaminose + tylactone => 5-O-beta-D-mycaminosyltylactone + dTDP + H(+)


name: PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Rattus norvegicus)


name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Sus scrofa)


name: endoribonuclease activity, cleaving miRNA-paired mRNA


name: H(+) + N,N-dihydroxy-L-pentahomomethionine <=> (E)-8-(methylsulfanyl)octanal oxime + CO2 + H2O


name: PI is exchanged with PC by PITPNB (Homo sapiens)


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + ATP = 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + ADP + H(+)


name: ROCK activation by RHO (Caenorhabditis elegans)


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Canis familiaris)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Xenopus tropicalis)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: C-terminal L-cysteinyl-[HypE protein] + carbamoyl adenylate = AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + H(+)


name: (-)-7-epi-alpha-selinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: ADP + H(+) + heme b(out) + phosphate => ATP + H2O + heme b(in)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Mus musculus)


name: COPI vesicle uncoating (Canis familiaris)


name: ORC1 translocates to the nucleus (Saccharomyces cerevisiae)


name: SRD5A2 dehydrogenates TEST to DHTEST (Homo sapiens)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Canis familiaris)


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O <=> 1-O-alkyl-2-acyl-sn-glycerol + a fatty acid + H(+)


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + Na(+)(out) => a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + Na(+)(in)


name: CO2 + isopentenyl phosphate + phosphate => (R)-3,5-bisphosphomevalonate + H(+)


name: ADP + carnosine + H(+) + phosphate => ATP + beta-alanine + L-histidine


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Mus musculus)


name: Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV (Canis familiaris)


name: DRD2 antagonist drugs bind to DRD2 (Danio rerio)


name: 6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O => 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA


name: chloride + FADH2 + L-tryptophan + O2 => 6-chloro-L-tryptophan + FAD + 2 H2O


name: BCKDH transfers CoA group from CoA-SH to BCAAs (Rattus norvegicus)


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Rattus norvegicus)


name: Caspase mediated cleavage of C-IAP1 (Danio rerio)


name: ADP-D-ribose + L-lysyl-[protein] => H2O + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein]


name: ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate


name: 6-(3-dimethylallyl)harmol + diphosphate => dimethylallyl diphosphate + harmol


name: COMT transfers Met to DOPAC to form HVA (Danio rerio)


name: L-tyrosine + S-adenosyl-L-methionine = 3-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Saccharomyces cerevisiae)


name: TMED2:TMED10 tetramer binds GPI anchored proteins (Canis familiaris)


name: HLTF polyubiquitinates monoubiquitinated PCNA (Saccharomyces cerevisiae)


name: (S)-malate + NADP(+) => CO2 + NADPH + pyruvate


name: (2Z,6E)-farnesyl diphosphate <=> beta-bisabolene + diphosphate


name: ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA (Rattus norvegicus)


name: 2 2-oxoglutarate + 2 O2 + preaustinoid A <=> berkeleytrione + 2 CO2 + H2O + 2 succinate


name: 3-hydroxybenzyl alcohol + O2 + reduced [NADPH--hemoprotein reductase] => gentisyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1-O-alkyl-2-acetyl-sn-glycerol + H(+) + phosphocholine => a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O


name: glyoxylate + H2O + NAD(+) + trimethylamine => glycine betaine + H(+) + NADH + O2


name: Activated FGFR4 binds PLCG1 (Sus scrofa)


name: taurine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoyl-taurine


name: (S)-3-O-geranylgeranylglyceryl phosphate synthase activity


name: UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Rattus norvegicus)


name: MT3 exchanges zinc for copper (Mus musculus)


name: an R-cob(III)alamin + apo-[alkylcobalamin reductase] + glutathione => an S-substituted glutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+)


name: WNTs are secreted in exosomes (Homo sapiens)


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Dictyostelium discoideum)


name: SGTA binds Tail-anchored protein (Sus scrofa)


name: dGTP + methylglyoxal <=> N(2)-(1-hydroxy-2-oxopropyl)-dGTP


name: an anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-[(6-O-(E)-4-coumaroyl)glucoside] + CoA => (E)-4-coumaroyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside


name: (2E)-2-butenoate + ATP + holo-[ACP] = (2E)-butenoyl-[ACP] + AMP + diphosphate


name: (R)-lactate + ATP + D-alanine <=> ADP + D-alanyl-(R)-lactate + phosphate


name: RAR:RXR binds SUMO-CRABP2:atRA (Mus musculus)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Mus musculus)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Plasmodium falciparum)


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Sus scrofa)


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Canis familiaris)


name: LONP1 binds mitochondrial inner membrane proteins (Mus musculus)


name: Surface deployment of platelet dense granule membrane components (Gallus gallus)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Gallus gallus)


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Drosophila melanogaster)


name: ADO oxidises 2AET to HTAU (Dictyostelium discoideum)


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Rattus norvegicus)


name: (2S,4R)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine => (2R)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Schizosaccharomyces pombe)


name: 32-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 32-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: glycine(in) + Na(+)(in) <=> glycine(out) + Na(+)(out)


name: (2E,4E)-2,4-dichloromuconate + 2 H(+) => 3,5-dichlorocatechol + O2


name: D-histidine + S-adenosyl-L-methionine => (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: NCOA2(869-1464) binds KAT6A(1-1118) (Homo sapiens)


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles


name: L-lysyl-[cytochrome c] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl-[cytochrome c] + S-adenosyl-L-homocysteine


name: 2-sulfenohercynine + AH2 + H(+) => A + ergothioneine + H2O


name: SLC34A3 cotransports Pi, 2Na+ (Xenopus tropicalis)


name: TFAP2C homodimer binds MYC and KDM5B (Sus scrofa)


name: 2-methoxy-6-(all-trans-heptaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine => 3-(all-trans-heptaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine


name: Grb7 binds to the active PDGF receptor (Bos taurus)


name: a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA => a 1,2-diacyl-sn-glycero-3-phosphate + CoA


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Danio rerio)


name: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) <=> H(+) + L-glutamyl-tRNA(Glu) + NADPH


name: 2,3-dihydrobiochanin A + NADP(+) => biochanin A + 2 H(+) + NADPH


name: ORC6 is phosphorylated on T195 (Gallus gallus)


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Homo sapiens)


name: ATP + L-histidyl-[protein] => ADP + H(+) + N(pros)-phospho-L-histidyl-[protein]


name: 2-demethylmenaquinone-8 + H(+) + NADH => 2-demethylmenaquinol-8 + NAD(+)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-3-phosphoethanolamine + a cardiolipin


name: BMAL1:CLOCK,NPAS2 heterodimer is phosphorylated and translocates to the nucleus (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: S-adenosyl-L-methionine + xanthohumol = 4-O-methylxanthohumol + H(+) + S-adenosyl-L-homocysteine


name: LHX2 binds to ROBO2 gene locus (Homo sapiens)


name: (Z)-3-hydroxypropyl glucosinolate + H2O = (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: S-adenosyl-L-methionine + scutellarein 4'-methyl ether = ladanein + S-adenosyl-L-homocysteine


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Homo sapiens)


name: Phosphorylation of INFAR1 by TYK2 (Sus scrofa)


name: ETA is phosphorylated to PETA by CHK/ETNK (Xenopus tropicalis)


name: 2 Fe(III)-[cytochrome c] + hydrogen sulfide => 2 Fe(II)-[cytochrome c] + H(+) + sulfur


name: 2-oxoglutarate + heptadecanoyl-CoA + O2 => 2-hydroxyheptadecanoyl-CoA + CO2 + succinate


name: avenanthramide A + CoA => (E)-4-coumaroyl-CoA + 5-hydroxyanthranilate


name: SUMOylation of NPM1 with SUMO2,3 (Mus musculus)


name: (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + O2 <=> (S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-1,3-oxazole-[protein] + H2O2


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Drosophila melanogaster)


name: lipid A phosphate methyltransferase activity


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Interaction of Tie2 and Grb7 (Bos taurus)


name: (6S)-NADPHX + ATP = ADP + H(+) + NADPH + phosphate


name: 1D-myo-inositol 3,4-bisphosphate + phosphate => 1D-myo-inositol 1,3,4-trisphosphate + H2O


name: p-S585-IL3RB binds 14-3-3 proteins (Canis familiaris)


name: Exocytosis of tertiary granule lumen proteins (Plasmodium falciparum)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Homo sapiens)


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Mus musculus)


name: phycocyanobilin-L-cysteinyl(84)-[C-phycocyanin beta-subunit] = (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[C-phycocyanin beta-subunit]


name: H2O + L-lysine + NAD(+) => (S)-2-amino-6-oxohexanoate + H(+) + NADH + NH4(+)


name: PA is dephosphorylated to DAG by LPIN (Sus scrofa)


name: H2O + mycophenolic acid O-acyl-beta-D-glucuronide = D-glucuronate + H(+) + mycophenolate


name: "mycophenolic acid acyl-glucuronide esterase"


name: RNA Pol II initiates transcription from damaged DNA template (Drosophila melanogaster)


name: DVL is recruited to the receptor (Sus scrofa)


name: a globoside GlcNAc-(beta1->6)-GalGb4Cer + H(+) + UDP => a globoside GalGb4Cer + UDP-N-acetyl-alpha-D-glucosamine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase] => 2 H(+) + H2O + N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase]


name: Collagen type XVI degradation by MMP9 (Homo sapiens)


name: Beta-catenin binds SOX proteins (Drosophila melanogaster)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Xenopus tropicalis)


name: Tankyrase ADP-ribosylates AXIN (Mus musculus)


name: The anterograde IFT train dissociates (Homo sapiens)


name: Alpha-1-Microglobulin is cleaved (Homo sapiens)


name: CLCN7:OSTM1 exchanges Cl- for H+ (Gallus gallus)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine


name: Inactivation of MAP2K1 by CDK1 (Danio rerio)


name: Activation of TAK1 complex bound to activated TLR4 complex (Gallus gallus)


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Caenorhabditis elegans)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Homo sapiens)


name: BCHE hydrolyzes ASA- (Xenopus tropicalis)


name: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + H(+)


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Sus scrofa)


name: NAD(+) + resolvin E1 <=> 18-oxo-resolvin E1 + H(+) + NADH


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Canis familiaris)


name: 7-oxo-25-hydroxycholesterol + H(+) + NADPH <=> 7beta-25-dihydroxycholesterol + NADP(+)


name: 9,10-dihydroxy-(12Z)-octadecenoate => 9,10-epoxy-(12Z)-octadecenoate + H2O


name: RNASEs bind bacterial LPS, PGN (Gallus gallus)


name: Interaction of DAP12 and TREM1 (Sus scrofa)


name: Prolysyl oxidase activation (Drosophila melanogaster)


name: Liganded-ALK dimer binds type I ALK-binding TKIs (Danio rerio)


name: DENND4s exchange GTP for GDP on RAB10 (Sus scrofa)


name: SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter (Homo sapiens)


name: AH2 + alstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => A + O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine


name: benzaldehyde + L-alanine => benzylamine + pyruvate


name: arginine + H2O => ornithine + urea [ARG2] (Bos taurus)


name: cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + H2O = (S)-2-hydroxypropylphosphonate + CMP + H(+)


name: NT5C2 tetramer dephosphorylates RBV-MP (Bos taurus)


name: adenosine 3',5'-bisphosphate + decanoyl-4'-phosphopantetheine + 2 H(+) => decanoyl-CoA + H2O


name: POFUT2 transfers fucose to TSR domain-containing proteins (Bos taurus)


name: a (2R,3R)-flavan-3-ol + 2 NADP(+) <=> an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Drosophila melanogaster)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + ouabagenin = dihydroouabagenin + 2 Fe(III)-[cytochrome c]


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Homo sapiens)


name: FANCD2 deubiquitination by USP1:WDR48 (Mus musculus)


name: H2O + hypoxanthine + O2 = H2O2 + xanthine


name: MIB2 ubiquitinates CYLD at K338, K530 (Mus musculus)


name: Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA (Rattus norvegicus)


name: Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Canis familiaris)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Rattus norvegicus)


name: Digestion of diacylglycerols by extracellular PTL:colipase (Bos taurus)


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Gallus gallus)


name: androst-4-ene-3,17-dione + H(+) + NADPH => NADP(+) + testosterone


name: FUT3 transfers L-fucose to Gal1,3GlcNAc (Caenorhabditis elegans)


name: Translocation of PDK1 to Plasma membrane (Caenorhabditis elegans)


name: L-glutamine(in) + L-threonine(out) + Na(+)(out) <=> L-glutamine(out) + L-threonine(in) + Na(+)(in)


name: Phosphorylation of LIMK-1 by PAK (Sus scrofa)


name: 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronate] + H(+) + UDP => 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + UDP-alpha-D-glucuronate


name: 2,6-dihydroxypyridine + H(+) + NADH + O2 = 2,3,6-trihydroxypyridine + H2O + NAD(+)


name: (3S)-hydroxyoctanoyl-CoA + NAD(+) => 3-oxooctanoyl-CoA + H(+) + NADH


name: gypsogenin + O2 + reduced [NADPH--hemoprotein reductase] => gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Regulation of KIF20A (MKL2) by phosphorylation (Canis familiaris)


name: 3-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 3,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)


name: ULK1 is dephosphorylated (Canis familiaris)


name: COX15 transforms heme O to heme A (Bos taurus)


name: 19-oxotestosterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 19-hydroxytestosterone + O2 + reduced [NADPH--hemoprotein reductase]


name: 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity


name: L1-FGFR cis-heterodimerization (Xenopus tropicalis)


name: Activation of RAC1 by VAV2/3 (Canis familiaris)


name: IP receptor can bind prostacyclin (Sus scrofa)


name: SEMA4A binds to PLXND1 (Drosophila melanogaster)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> (R)-cembrene A + diphosphate


name: a 1-acyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) = a 1-acyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: biphenyl-2,2',3-triol + H(+) + NADH + O2 <=> biphenyl-2,2',3,3'-tetraol + H2O + NAD(+)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)


name: tBID binds to inactive BAK protein (Mus musculus)


name: PLK1 phosphorylates OPTN (Rattus norvegicus)


name: Phosphorylation of SHC1 by ERBB4 homodimers (Gallus gallus)


name: an N-acylsphinganine + UDP-alpha-D-glucose => an N-acyl-beta-D-glucosyl-(1<->1')-sphinganine + H(+) + UDP


name: ATM recognizes H2AFX-Nucleosomes (Mus musculus)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Drosophila melanogaster)


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Saccharomyces cerevisiae)


name: (S)-nornicotine + formaldehyde + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-nicotine + O2 + reduced [NADPH--hemoprotein reductase]


name: NOTCH4 gene transcription is inhibited by RUNX1 (Homo sapiens)


name: Formation of hydroxylysyl-pyridinoline cross-links (Caenorhabditis elegans)


name: a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O


name: (9Z)-octadecenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+) => 1-O-(1Z-hexadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: a neolactoside nLc4Cer + GDP-beta-L-fucose = a neolactoside IV(2)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: (2R)-3-phospho-glyceroyl phosphate + 2-deoxy-alpha-D-ribose 1-phosphate => (2R)-3-phosphoglycerate + 2-deoxy-alpha-D-ribose 1,5-bisphosphate + H(+)


name: D-glyceraldehyde 3-phosphate + H2O + NAD(+) = (2R)-3-phosphoglycerate + 2 H(+) + NADH


name: [DsrC protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide = [DsrC protein]-dithiol + 2 AH2 + H(+) + sulfite


name: bPIX exchanges GTP for GDP on RAC, activating it (Rattus norvegicus)


name: (+)-artemisinic aldehyde + H2O + NADP(+) => (+)-artemisinate + 2 H(+) + NADPH


name: LIPs hydrolyse TG to DAG and RCOOH (Homo sapiens)


name: CPN, CPB2 cleave C3a, C5a (Rattus norvegicus)


name: Tachykinin receptor 1 (NK1) binds to substance P (Rattus norvegicus)


name: Na(+)(out) + tellurite(out) => Na(+)(in) + tellurite(in)


name: (Z)-gamma-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: 2-oxopentanoate + L-kynurenine <=> H2O + kynurenate + L-2-aminopentanoate


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)


name: acetone + H(+) + NADH + O2 => H2O + hydroxyacetone + NAD(+)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Mus musculus)


name: D-fructose + phosphate => beta-D-fructose 1-phosphate + H2O


name: H2O + mevastatin <=> (S)-2-methylbutanoate + compactin diol lactone + H(+)


name: MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) (Bos taurus)


name: 2''-O-dodecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide => H2O + N(6)-dodecanoyl-L-lysyl-[protein] + NAD(+)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => a cardiolipin + ethanolamine


name: (11Z)-eicosenoate + glycerol + H(+) => 1-(11Z-eicosenoyl)-glycerol + H2O


name: (E)-caffeate + ATP + H(+) => (E)-caffeoyl-AMP + diphosphate


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + H(+) => H2O + norlichexanthone


name: 3',5'-di-O-methyltricetin + S-adenosyl-L-methionine => 3',4',5'-O-trimethyltricetin + H(+) + S-adenosyl-L-homocysteine


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Canis familiaris)


name: beta-L-fucose + NADP(+) <=> H(+) + L-fucono-1,5-lactone + NADPH


name: Tetrastatin binds integrin alphaVbeta3 (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine => a 1,2-diacyl-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine


name: Transphosphorylation of JAK1 (Canis familiaris)


name: estrone 3-sulfate + H2O = estrone + H(+) + sulfate


name: Orexin 1 receptor can bind orexin-A neuropeptide (Homo sapiens)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-hapalindole U


name: Activated NTRK2 binds FRS2 (Gallus gallus)


name: H2O + indole-3-carbaldehyde + O2 <=> H(+) + H2O2 + indole-3-carboxylate


name: Localization of CBL:GRB2 to the membrane (Danio rerio)


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Schizosaccharomyces pombe)


name: a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Homo sapiens)


name: ATP + beta-D-ribosylnicotinate = ADP + H(+) + nicotinate beta-D-ribonucleotide


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (22S)-22-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Rattus norvegicus)


name: PP2A-B56 dephosphorylates centromeric cohesin (Sus scrofa)


name: CWO binds to cwo gene and represses transcription (Drosophila melanogaster)


name: [DNA-directed RNA polymerase] + ATP <=> ADP + H(+) + phospho-[DNA-directed RNA polymerase]


name: di-trans,poly-cis-dolichol + phosphate => a dolichyl phosphate + H2O


name: eicosanoate + glycine => H2O + N-eicosanoylglycinate


name: (3R)-3-isocyanylbutanoate + ATP + H(+) <=> (3R)-3-isocyanylbutanoyl-AMP + diphosphate


name: mRNA6 is translated to protein 6 (Homo sapiens)


name: H2O + lovastatin = (S)-2-methylbutanoate + H(+) + monacolin J


name: PTPN3 binds p-T183,Y185 MAPK12 (Mus musculus)


name: (2R,3S)-3-isopropylmalate + NAD(+) <=> 4-methyl-2-oxopentanoate + CO2 + NADH


name: (Z)-2-(indol-3-yl)-1-thioacetohydroximate + UDP-alpha-D-glucose = (Z)-indolylmethyl desulfoglucosinolate + UDP


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Mus musculus)


name: TFIIS-mediated recovery of elongation from arrest (Homo sapiens)


name: 16alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + progesterone + reduced [NADPH--hemoprotein reductase]


name: 9,10-epoxy-(12Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-9,10-epoxy-(12Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: kaempferide + S-adenosyl-L-methionine <=> 7,4'-O-dimethylkaempferol + H(+) + S-adenosyl-L-homocysteine


name: ACBD6 binds LCFA-CoA (Plasmodium falciparum)


name: ATP + H2O + L-alanyl-L-aspartate(out) <=> ADP + H(+) + L-alanyl-L-aspartate(in) + phosphate


name: GDP-beta-L-fucose + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate => GDP + H(+) + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: ACY3:Zn2+ dimer hydrolyses mercapturic acids (Xenopus tropicalis)


name: GDP + H(+) + O-phospho-L-seryl-[protein] => GTP + L-seryl-[protein]


name: H2O + prostaglandin J2 => prostaglandin D2


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Saccharomyces cerevisiae)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-galactose


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Drosophila melanogaster)


name: ACE2 hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) (Gallus gallus)


name: PLK1 phosphorylates GORASP1 (Schizosaccharomyces pombe)


name: low-density lipoprotein particle binding


name: 3-sulfanyl-1-hexanol + NH4(+) + pyruvate => H2O + S-3-(hexan-1-ol)-L-cysteine


name: H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine <=> 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP


name: NCOA3 binds ESR1:estrogen:TFGA gene (Gallus gallus)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+) => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O


name: Association of procollagen type XVII (Homo sapiens)


name: LIPC dimer hydrolyses TAG to DAG and FA (Danio rerio)


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-GMP <=> GMP + H(+) + lactate


name: 2-acetyl-3,4a,8,10,11,12a-hexahydroxy-1,4,4a,5,12,12a-hexahydrotetracene-1,12-dione + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + TAN-1612


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)


name: C5a receptor binds C5a anaphylatoxin (Canis familiaris)


name: FAD(out) + NAD(+)(in) <=> FAD(in) + NAD(+)(out)


name: 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + H(+) + NADPH + O2 <=> H2O + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate + NADP(+)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Sus scrofa)


name: (S)-norreticuline + S-adenosyl-L-methionine <=> (S)-norcodamine + H(+) + S-adenosyl-L-homocysteine


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Dictyostelium discoideum)


name: L-fuconate <=> 2-dehydro-3-deoxy-L-fuconate + H2O


name: 2-hydroxy-1,4-benzoquinone + H2O + NADP(+) + nitrite => 4-nitrocatechol + NADPH + O2


name: ATP + L-tryptophan + tRNA(Trp) => AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)


name: (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+) => H2O + L-lysyl-[protein] + O2


name: Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) (Bos taurus)


name: Cho is acetylated to AcCho by CHAT (Rattus norvegicus)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine <=> 1,3,3'-tri-O-methyl-4alpha-mannobiose + H(+) + S-adenosyl-L-homocysteine


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)


name: beta-D-Gal-(1<->1')-Cer + UDP-alpha-D-galactose <=> alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer + H(+) + UDP


name: Expression of PLAC8 in the nephric duct (Homo sapiens)


name: 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate => 2'-deamino-2'-hydroxyneamine + 2-oxoglutarate


name: CDC42:GTP binds CBL:Beta-Pix (Homo sapiens)


name: ATP + H2O + L-methionyl-L-alanine(out) => ADP + H(+) + L-methionyl-L-alanine(in) + phosphate


name: DAG is metabolized by DAGL to 2-AG (Caenorhabditis elegans)


name: Myosin phosphatase dephosphorylates PLK1 (Rattus norvegicus)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Drosophila melanogaster)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: GTP + H(+) + valienol 1-phosphate <=> diphosphate + GDP-valienol


name: Transhomodimerization of Nectins (Xenopus tropicalis)


name: brain-derived neurotrophic factor binding


name: Trafficking of GluR2-containing AMPA receptors to synapse (Gallus gallus)


name: p-PKR dimer phosphorylates DHX9 (Rattus norvegicus)


name: 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: dehydroechinulin + diphosphate => dimethylallyl diphosphate + isoechinulin A


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Mus musculus)


name: 3-deoxyglucosone + H2O + NAD(+) = 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH


name: 2-demethylmenaquinone-8 + H(+) + NADPH => 2-demethylmenaquinol-8 + NADP(+)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Gallus gallus)


name: (E)-6-hydroxyferuloyl-CoA = CoA + scopoletin


name: (2E)-geranyl diphosphate => beta-thujene + diphosphate


name: Translocation of CaN:CaM:NFAT to nucleus (Bos taurus)


name: Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen (Bos taurus)


name: DDAH1,2 hydrolyses ADMA to DMA and L-Cit (Canis familiaris)


name: NTHL1 D239Y does not cleave thymine glycol (Tg) (Homo sapiens)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Plasmodium falciparum)


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Mus musculus)


name: indole-3-pyruvate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tryptophan


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a 1-acyl-sn-glycero-3-phosphoethanolamine + a cardiolipin


name: PHB and all-E-10PrP2 are combined into DHB by COQ2 (Xenopus tropicalis)


name: (E)-4-coumaroyl-CoA + 5-hydroxyanthranilate <=> avenanthramide A + CoA


name: SREBP1A,2 binds the MVK promoter (Homo sapiens)


name: TXLNA (IL14) binds syntaxin4 (Drosophila melanogaster)


name: SIRP alpha binds CD47 (Rattus norvegicus)


name: Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)


name: ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)


name: eNoSC deacetylates histone H3 (Dictyostelium discoideum)


name: Interaction of SIGLEC14/15/16 and DAP12 (Sus scrofa)


name: all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] => all-trans-zeaxanthin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Gallus gallus)


name: (+)-(R)-germacrene A + O2 + reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Epsin family proteins bind ubiquitinated cargo (Rattus norvegicus)


name: (6S)-5,6,7,8-tetrahydrofolate + 2 H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide => (6R)-5,10-methenyltetrahydrofolate + H2O + N(1)-(5-phospho-beta-D-ribosyl)glycinamide


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Canis familiaris)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Homo sapiens)


name: a very-long-chain 2,3-saturated fatty acyl-CoA + NADP(+) => a very-long-chain (2E)-enoyl-CoA + H(+) + NADPH


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Sus scrofa)


name: Misfolded proteins:HDAC6:Dynein motor binds microtubule (Homo sapiens)


name: a mannosylinositol-1-phosphophytoceramide + H2O => an inositol-1-phosphophytoceramide + beta-D-mannose


name: (9Z)-octadecenoate + O2 => (2R,9Z)-2-hydroperoxyoctadecenoate


name: a carboxylate + an L-alpha-amino acid => an N-acyl-L-amino acid + H2O


name: 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 <=> a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate


name: 1D-myo-inositol hexakisphosphate + ATP <=> 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP


name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Caenorhabditis elegans)


name: SREBP1A,1C binds the ACACB promoter (Homo sapiens)


name: IDS hydrolyses Heparan sulfate chain(5) (Sus scrofa)


name: H(+) + NADH + O2 + protodeoxyviolaceinate = deoxyviolaceinate + H2O + NAD(+)


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Danio rerio)


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Sus scrofa)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Homo sapiens)


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Homo sapiens)


name: Syk activation leads to SLP-76 activation (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+)


name: FLT3 phosphorylates GRB10 (Homo sapiens)


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphinganine + H2O = beta-D-glucose + N-hexadecanoylsphinganine


name: HMGB1 binds LTP (Schizosaccharomyces pombe)


name: STAMBPL1 is a deubiquitinase (Dictyostelium discoideum)


name: erythritol + NAD(+) => D-erythrulose + H(+) + NADH


name: H(+) + L-methionyl-[protein] + NADPH + O2 => H2O + L-methionyl-S-oxide-[protein] + NADP(+)


name: D-glucarate(in) + H(+)(in) <=> D-glucarate(out) + H(+)(out)


name: "Isomerases altering macromolecular conformation"


name: PPT1 hydrolyses palmitoylated proteins (Bos taurus)


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Gallus gallus)


name: MRRF binds 55S ribosome:mRNA:tRNA (Homo sapiens)


name: ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA (Homo sapiens)


name: 2-glutathionyl-2-methylbut-3-enal + H2O + NAD(+) => 2-glutathionyl-2-methylbut-3-enoate + 2 H(+) + NADH


name: N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Caenorhabditis elegans)


name: Binding of TFIIIC to Type 2 promoter (Schizosaccharomyces pombe)


name: alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP-beta-L-fucose => a neolactoside IV(3)-alpha-Gal,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome (Rattus norvegicus)


name: RAC2 GAPs stimulate RAC2 GTPase activity (Xenopus tropicalis)


name: H(+)(in) + L-galactose(in) => H(+)(out) + L-galactose(out)


name: Gi activation by P2Y purinoceptor 12 (Homo sapiens)


name: ADP + an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A


name: (+)-dehydrodiconiferyl acid + 2 a quinone + H2O <=> (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Mus musculus)


name: CTP(out) + dUTP(in) <=> CTP(in) + dUTP(out)


name: cAMP induces dissociation of inactive PKA tetramers (Bos taurus)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Schizosaccharomyces pombe)


name: alpha-D-glucose 1-phosphate + H(+) + UTP <=> diphosphate + UDP-alpha-D-glucose


name: 7,8-dihydroneopterin 3'-phosphate => 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde phosphate


name: 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA <=> 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: UDP-alpha-D-glucose + vanillate <=> 1-O-(4-hydroxy-3-methoxybenzoyl)-beta-D-glucose + UDP


name: Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Rattus norvegicus)


name: Transport of antigen loaded MHC II molecules to surface (Sus scrofa)


name: CUL3:RBX1 ubiquitinates KEAP1 (Gallus gallus)


name: N-terminal protein N-methyltransferase activity


name: NPM1-ALK-stimulated PRF1 gene expression (Homo sapiens)


name: Tropoelastin forms aggregate globules (Gallus gallus)


name: Aquaporins passively transport urea out of cells (Gallus gallus)


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Dictyostelium discoideum)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Danio rerio)


name: 3,4-dinitrotoluene + NADH + O2 = 4-methyl-6-nitrocatechol + NAD(+) + nitrite


name: p-VAV family:PIP3 binds RAC1:GDP (Xenopus tropicalis)


name: Activated PCLG1 dissociates from NTRK3 (Mus musculus)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Rattus norvegicus)


name: an N-acylsphing-4-enine + H2O = a fatty acid + sphing-4-enine


name: H2O + neurotensin <=> L-leucine + neurotensin-(1-12)


name: PTPN3 dephosphorylates MAPK12 (Xenopus tropicalis)


name: 1,4-dihydroxy-2-naphthoate + all-trans-hexaprenyl diphosphate + H(+) = 2-demethylmenaquinol-6 + CO2 + diphosphate


name: a quinol + orotate => (S)-dihydroorotate + a quinone


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: (2E,6E)-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate


name: IL34 dimer:SDC1 binds CSF1R (Bos taurus)


name: H2O + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2) = beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: 1,7-dimethylxanthine + H(+) + NADPH + O2 <=> 7-methylxanthine + formaldehyde + H2O + NADP(+)


name: CTNNB1 S37 mutants aren't phosphorylated by GSK3beta (Homo sapiens)


name: TLE forms non-functional complexes with AES (Homo sapiens)


name: ligase activity, forming nitrogen-metal bonds, forming coordination complexes


name: ProGIP translocates from the ER Lumen to secretory granules (Homo sapiens)


name: PCK1 phosphorylates OA to yield PEP (Dictyostelium discoideum)


name: beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enine + cholesterol => cholesteryl 3-beta-D-glucoside + N-(15Z-tetracosenoyl)-sphing-4-enine


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Canis familiaris)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Canis familiaris)


name: MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Canis familiaris)


name: ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA (Bos taurus)


name: 2-aminoprop-2-enoate + allylsulfenate => alliin


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Schizosaccharomyces pombe)


name: carboxyspermidine + H(+) = CO2 + spermidine


name: PAK1 phosphorylates myosin phosphatase (Rattus norvegicus)


name: ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Xenopus tropicalis)


name: prostaglandin A2-S-(R)-glutathione => glutathione + prostaglandin A2


name: D-erythrose 4-phosphate + dihydroxyacetone phosphate <=> D-sedoheptulose 1,7-bisphosphate


name: Bile salts and acids dissociate from ALB (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate + H(+)


name: decanoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + decanoyl-4'-phosphopantetheine + 2 H(+)


name: CREB3L3 translocates from the cytosol to the nucleus (Caenorhabditis elegans)


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Sus scrofa)


name: ATM phosphorylates TP53BP1 at DNA DSBs (Rattus norvegicus)


name: ATM phosphorylates MDC1 (Drosophila melanogaster)


name: alpha-D-glucosamine 1-phosphate => D-glucosamine 6-phosphate


name: Homodimerization of VEGF proteins (Homo sapiens)


name: 14-3-3 zeta binding allows recruitment of PI3K (Homo sapiens)


name: 2-oxoglutarate(in) + oxaloacetate(out) => 2-oxoglutarate(out) + oxaloacetate(in)


name: GAP binds to PDGF-beta receptors only (Rattus norvegicus)


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Mus musculus)


name: DLL1 gene expression is inhibited by MECP2 (Homo sapiens)


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Mus musculus)


name: STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Canis familiaris)


name: (+)-epi-isozizaene + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> albaflavenone + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: H(+) + L-fuconate => H2O + L-fucono-1,4-lactone


name: diphosphate + fusicocca-2,10(14)-diene => geranylgeranyl diphosphate


name: P4HB forms mixed disulphides with Hh precursors (Homo sapiens)


name: an N-acyl-D-glucosamine 6-phosphate => an N-acyl-D-mannosamine 6-phosphate


name: HRASLS transfer acyl group from PC to PE to form NAPE (Canis familiaris)


name: (2R)-3-phosphoglycerate + NAD(+) => 3-phosphooxypyruvate + H(+) + NADH


name: Proteasome degrades polyubiquitinated PTEN (Drosophila melanogaster)


name: H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + phosphate <=> diphosphate + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase]


name: a bacteriochlorophyllide d + H2O + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + a bacteriochlorophyllide f + 2 H(+) + 2 L-methionine


name: a long chain fatty alcohol + FMN + H(+) + H2O => a long-chain alkane + FMNH2 + O2


name: SMO translocates to the cilium (Bos taurus)


name: TPX2 binds AURKA at centrosomes (Sus scrofa)


name: Cytosolic PLK1 translocates to the nucleus (Plasmodium falciparum)


name: adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate + H(+) => 3'-phosphoadenylyl sulfate + 3beta-hydroxyandrost-5-en-17-one


name: ATP + dodecanoate + holo-[ACP] <=> AMP + diphosphate + dodecanoyl-[ACP]


name: (E)-5-hydroxyferulate + S-adenosyl-L-methionine = (E)-sinapate + H(+) + S-adenosyl-L-homocysteine


name: CoA + H(+) + N(6)-butanoyl-L-lysyl-[protein] => butanoyl-CoA + L-lysyl-[protein]


name: a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine => an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine


name: androstan-3alpha,17beta-diol + NAD(+) => 17beta-hydroxyandrostanone + H(+) + NADH


name: holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Bos taurus)


name: SENP1,2,5 proteolytically process SUMO1 (Rattus norvegicus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: 9,10-epoxyoctadecanoate + H2O = 9,10-dihydroxyoctadecanoate


name: 4-fumarylacetoacetate + H2O <=> acetoacetate + fumarate + H(+)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Sus scrofa)


name: PELI1 ubiquitinates RIPK3 at K363 (Bos taurus)


name: TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Xenopus tropicalis)


name: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine <=> D-glyceraldehyde 3-phosphate + H2O + L-tryptophan


name: Phosphorylation of INFAR1 by TYK2 (Homo sapiens)


name: 5-deoxy-5-amino-3-dehydroshikimate => 3-amino-5-hydroxybenzoate + H(+) + H2O


name: (4R)-hydroxysphinganine + a fatty acid => an N-acyl-(4R)-4-hydroxysphinganine + H2O


name: MMP2, MMP9 cleave SCUBE3 (Canis familiaris)


name: 2-oxoglutarate + 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate <=> 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + L-glutamate


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Bos taurus)


name: 3 H(+) + 3 malonyl-CoA = 1,3,5-trihydroxybenzene + 3 CO2 + 3 CoA


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Homo sapiens)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Canis familiaris)


name: 1,2-dioctanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O => H(+) + octanoate + octanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: PP2A dephosphorylates p-RHO to RHO (Canis familiaris)


name: glycylglycine => 2,5-dioxopiperazine + H2O


name: acetyl-CoA + L-tryptophan + malonyl-CoA => CO2 + 2 CoA + cyclo-acetoacetyl-L-tryptophan + H2O


name: Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Bos taurus)


name: HDAC1:2-containing complex deacetylate histones (Saccharomyces cerevisiae)


name: a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Sus scrofa)


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Caenorhabditis elegans)


name: RHOD auto-activates (Schizosaccharomyces pombe)


name: CYP4F2, 4F3 20-hydroxylate LTB4 (Mus musculus)


name: PGH2 is isomerised to PGD2 by HPGDS (Caenorhabditis elegans)


name: 4-amino-L-phenylalanine + S-adenosyl-L-methionine = 4-methylamino-L-phenylalanine + H(+) + S-adenosyl-L-homocysteine


name: 24-methylenecycloartanol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: Exocytosis of ficolin-rich granule lumen proteins (Xenopus tropicalis)


name: CCNG1 recruits PP2A-PPP2R5C to MDM2 (Bos taurus)


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Caenorhabditis elegans)


name: CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein] => L-lysyl-[protein] + lactoyl-CoA


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (22S)-22-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 8-hydroxy-7-methoxyflavone + S-adenosyl-L-methionine => 7,8-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: WWP2 ubiquitinates NOTCH3 (Mus musculus)


name: (S)-lactaldehyde + H2O + NAD(+) = (S)-lactate + 2 H(+) + NADH


name: (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] <=> 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Mus musculus)


name: Formation of CSL NCOR corepressor complex (Xenopus tropicalis)


name: (indol-3-yl)acetate + CO2 + H2O + NADP(+) => H(+) + indole-3-pyruvate + NADPH + O2


name: cyclo(L-phenylalanyl-L-leucyl) + O2 <=> cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2


name: 2 L-ascorbate + N-(9Z,12Z,15Z)-octadecatrienoylglycine + O2 <=> H2O + 2 monodehydro-L-ascorbate radical + N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine


name: (E)-alpha-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: H(+) + N-carbamoyl-L-aspartate => (S)-dihydroorotate + H2O


name: a cholesterol ester(out) => a cholesterol ester(in)


name: PIAS2-2 SUMOylates THRA with SUMO1 (Sus scrofa)


name: AFG3L2 binds mitochondrial inner membrane proteins (Xenopus tropicalis)


name: Cdh1:APC/C complex binds EHMT1:EHMT2 (Bos taurus)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Homo sapiens)


name: an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O => an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + D-galactosamine


name: peonidin + UDP-alpha-D-galactose = peonidin 3-O-beta-D-galactoside + UDP


name: carbohydrate derivative transmembrane transporter activity


name: H2O2 + IC-asc-DeltaC9-CoA => IC-asc-C9-CoA + O2


name: alpha-D-galactosyl-(1->3)-1D-myo-inositol + raffinose = myo-inositol + stachyose


name: ATP + coproporphyrin I(in) + H2O = ADP + coproporphyrin I(out) + H(+) + phosphate


name: 3-oxohexacosanoyl-CoA + H(+) + NADPH => (3R)-hydroxyhexacosanoyl-CoA + NADP(+)


name: 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA => H(+) + isopentadecanoyl-CoA + L-serine


name: EGR-dependent NAB2 gene expression (Homo sapiens)


name: ATP + D-cystine(out) + H2O = ADP + D-cystine(in) + H(+) + phosphate


name: 1,2-dioctanoyl-sn-glycero-3-phosphate + H2O = 1,2-dioctanoyl-sn-glycerol + phosphate


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Xenopus tropicalis)


name: 2-ethylhexanal + CO2 + H(+) + succinate + sulfate => 2-ethylhexyl sulfate + 2-oxoglutarate + O2


name: 2-oxo-3-sulfanylpropanoate + L-glutamate => 2-oxoglutarate + L-cysteine


name: (3S)-3-hydroxy-L-lysyl-[protein] + CO2 + succinate => 2-oxoglutarate + L-lysyl-[protein] + O2


name: a 5'-end diphospho-adenosine in mRNA + GTP + H(+) <=> a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + diphosphate


name: abieta-8,11,13-triene + O2 + reduced [NADPH--hemoprotein reductase] <=> ferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CCNK binds CDK12 (Saccharomyces cerevisiae)


name: 2 A + glycine => 2 AH2 + CO2 + hydrogen cyanide


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Canis familiaris)


name: Formation of collagen networks (Caenorhabditis elegans)


name: ADP + glutathione + H(+) + phosphate => ATP + gamma-L-glutamyl-L-cysteine + glycine


name: H(+) + NADPH + prostaglandin D2 => 11beta-prostaglandin F2 + NADP(+)


name: oxidoreductase activity, acting on peroxide as acceptor


name: 3-methyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + S-adenosyl-L-methionine <=> 3,5-dimethyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + H(+) + S-adenosyl-L-homocysteine


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate => 15-cis-phytoene + 2 diphosphate


name: 3 H(+) + 3 malonyl-CoA + N-methylanthraniloyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O


name: 5,6-dihydrouridine(17) in tRNA + NAD(+) = H(+) + NADH + uridine(17) in tRNA


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Drosophila melanogaster)


name: Formation of the Spliceosomal Bact complex (Homo sapiens)


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Rattus norvegicus)


name: ATP(in) + CoA(in) + dodecanoate(out) + H(+)(out) <=> AMP(in) + diphosphate(in) + dodecanoyl-CoA(in) + H(+)(in)


name: GRK2 sequesters activated Gq (Homo sapiens)


name: Separation of elongating transcript from template (Caenorhabditis elegans)


name: SARS-CoV-1 9b recruits ITCH to MAVS  (Homo sapiens)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + H2O <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + phosphate


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphate + H(+) + NADPH => 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphate + NADP(+)


name: 15-hydroxypentadecanoate + ATP + CoA = 15-hydroxypentadecanoyl-CoA + AMP + diphosphate


name: DNA nucleases unhook the interstrand crosslink (ICL) (Bos taurus)


name: [thioredoxin]-disulfide + dCDP + H2O = [thioredoxin]-dithiol + CDP


name: (13Z)-docosenoyl-CoA + (4R)-hydroxysphinganine = CoA + H(+) + N-(13Z-docosenoyl)-4R-hydroxysphinganine


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Rattus norvegicus)


name: hexadecanoyl-CoA + N-terminal L-cysteinyl-[protein] => CoA + H(+) + N-terminal N-hexadecanoyl-L-cysteinyl-[protein]


name: RFC binding displaces Pol Alpha (Bos taurus)


name: MECP2 mutants R133C ,D121G, R133H and S134F do not bind 5hmC-DNA (Homo sapiens)


name: Recruitment of CDK11p58 to the centrosomes (Mus musculus)


name: HMGCR dimer reduces bHMG-CoA to MVA (Xenopus tropicalis)


name: p-T,Y MAPK dimers translocate to nucleus (Dictyostelium discoideum)


name: PLC gamma 2-mediated PIP2 hydrolysis (Homo sapiens)


name: CERK phosphorylates CERA to form C1P (Caenorhabditis elegans)


name: Export of peptide loaded MHC class I complex to PM (Mus musculus)


name: SLC52A1,2,3 transport RIB from extracellular region to cytosol (Canis familiaris)


name: diphosphate + notoamide S => 6-hydroxydeoxybrevianamide E + dimethylallyl diphosphate


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Mus musculus)


name: monoatomic ion antiporter activity involved in regulation of presynaptic membrane potential


name: cytidine(2498) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methylcytidine(2498) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + H2O = 5-amino-6-(5-phospho-D-ribitylamino)uracil + NH4(+)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Danio rerio)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Drosophila melanogaster)


name: ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB (Mus musculus)


name: dihydrochelirubine + NAD(+) => chelirubine + NADH


name: 2 Fe(II)-[leghemoglobin] + H(+) + NAD(+) => 2 Fe(III)-[leghemoglobin] + NADH


name: NGF binding to p75NTR inactivates RHOA (Gallus gallus)


name: Autoubiquitination of phospho-COP1(Ser-387 ) (Bos taurus)


name: Interaction of DAP12 and TREM2 (Canis familiaris)


name: (2S,9S)-annullatin H + 2 A <=> (2S,9S)-annullatin D + 2 AH2


name: p-T182 MAPKAPK5 phosphorylates FOXO3 (Gallus gallus)


name: RHOA:GTP translocates to the ER membrane (Mus musculus)


name: 2 Fe(II)-[cytochrome c] + 2 H(+) + tetrathionate => 2 Fe(III)-[cytochrome c] + 2 thiosulfate


name: a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Caenorhabditis elegans)


name: (R)-pantoate + NADP(+) => 2-dehydropantoate + H(+) + NADPH


name: SLC22A1 transports Cipro into hepatic cell (Xenopus tropicalis)


name: Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine (Homo sapiens)


name: 1-tetracosanoylglycerol + H2O => glycerol + H(+) + tetracosanoate


name: dopamine + formaldehyde <=> H2O + norsalsolinol


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol <=> (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone


name: 10-oxodecanoate + H(+) + NADH => 10-hydroxydecanoate + NAD(+)


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Canis familiaris)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Canis familiaris)


name: 5-hydroxythiophene-2-carbonyl-CoA + H2O = 4-carboxy-2-thioxobutanoyl-CoA


name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Sus scrofa)


name: 2-oxoglutarate + L-histidyl-[ribosomal protein uL15] + O2 <=> (3S)-3-hydroxy-L-histidyl-[ribosomal protein uL15] + CO2 + succinate


name: H2O + hexylamine + NAD(+) = H(+) + hexanal + NADH + NH4(+)


name: Ubiquitination of phospho-p27/p21 (Drosophila melanogaster)


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Canis familiaris)


name: sn-glycerol 3-phosphate + UDP-alpha-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP


name: Delta(1)-pyrroline-(4S)-hydroxy-2-carboxylate + 2 H(+) + NADPH => cis-4-hydroxy-L-proline + NADP(+)


name: L-aspartate(in) + succinate(out) = L-aspartate(out) + succinate(in)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Caenorhabditis elegans)


name: [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-1-O,3-O-dimethyl-alpha-D-mannose + GDP-alpha-D-mannose <=> alpha-D-mannosyl-(1->4)-[3-O-methyl-alpha-D-mannosyl-(1->4)](n)-1-O,3-O-dimethyl-alpha-D-mannose + GDP + H(+)


name: corticosterone + NADP(+) <=> 11-dehydrocorticosterone + H(+) + NADPH


name: 3-carboxy-cis,cis-muconate + 2 H(+) => 3,4-dihydroxybenzoate + O2


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Schizosaccharomyces pombe)


name: CREBBP binds FOXO1 (Drosophila melanogaster)


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Gallus gallus)


name: 2-hydroxy-2-methylbutanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-2-methylbutanenitrile + O2 + reduced [NADPH--hemoprotein reductase]


name: DHDB is methylated to MHDB by COQ3 (Xenopus tropicalis)


name: a long-chain fatty acyl-AMP + holo-[ACP] => a long-chain fatty acyl-[ACP] + AMP + H(+)


name: p-S295-PDE3B hydrolyses cAMP to AMP (Caenorhabditis elegans)


name: Beta-catenin recruits CDC73 and LEO1 (Gallus gallus)


name: 4-(methylamino)butanoate + H2O + O2 => H2O2 + methylamine + succinate semialdehyde


name: a ribonucleotidyl-ribonucleotide-RNA + H2O => a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+)


name: 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + octanoyl-CoA


name: ATP + L-glutamate + putrescine <=> ADP + gamma-L-glutamylputrescine + H(+) + phosphate


name: biphenyl-3,5-diol + 4 CO2 + 4 CoA => benzoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: DHAP is converted to 1-acyl GO3P by GNPAT (Xenopus tropicalis)


name: (8R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: Inactivation of Lck by Csk (Rattus norvegicus)


name: Calcium Influx through Voltage-gated Calcium Channels (Caenorhabditis elegans)


name: B4GALTs transfer Gal to the keratan chain (Danio rerio)


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Saccharomyces cerevisiae)


name: 2 H(+) + ternatin C5 + UDP => delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP-alpha-D-glucose


name: 1-butanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA


name: hercynine + L-cysteine + O2 = H2O + S-(hercyn-2-yl)-L-cysteine S-oxide


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Rattus norvegicus)


name: aspulvinone E + H2O => 2 3-(4-hydroxyphenyl)pyruvate


name: 11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione <=> (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoate


name: snRNP:Snurportin complex formation (Caenorhabditis elegans)


name: H2O + L-ectoine => (2S)-2-acetamido-4-aminobutanoate


name: L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[GAPDH] = L-cysteinyl-[GAPDH] + S-nitroso-L-cysteinyl-[protein]


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Rattus norvegicus)


name: Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol (Homo sapiens)


name: homogentisate + O2 => maleylacetoacetate (Canis familiaris)


name: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate