name: an N-acyl-sphingoid base + H(+) + phosphocholine => an N-(acyl)-sphingosylphosphocholine + H2O


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Xenopus tropicalis)


name: 4-hydroxynonanal + NADP(+) <=> (E)-4-hydroxynon-2-enal + H(+) + NADPH


name: keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O


name: ATP + H2O + L-methionyl-L-alanine(out) <=> ADP + H(+) + L-methionyl-L-alanine(in) + phosphate


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Canis familiaris)


name: Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB (Gallus gallus)


name: SUMOylation of XPC with SUMO1 (Rattus norvegicus)


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Bos taurus)


name: PTN and MDK bind to PTPRZ (Gallus gallus)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Bos taurus)


name: 3-sulfinopropanoyl-CoA + H2O => H(+) + propanoyl-CoA + sulfite


name: ATP + dodecanoate + holo-[ACP] = AMP + diphosphate + dodecanoyl-[ACP]


name: a cytidine in 28S rRNA + S-adenosyl-L-methionine => a 5-methylcytidine in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Oligomerization of p-CARMA1 (Sus scrofa)


name: (2E)-octenoyl-CoA + H(+) + NADH = NAD(+) + octanoyl-CoA


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Sus scrofa)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Sus scrofa)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Bos taurus)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Bos taurus)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Homo sapiens)


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Bos taurus)


name: beta-muricholate + deoxycholoyl-CoA <=> beta-muricholoyl-CoA + deoxycholate


name: AH2 + L-arginyl-[methyl-coenzyme M reductase] + 2 S-adenosyl-L-methionine => (5S)-C-methyl-L-arginyl-[methyl-coenzyme M reductase] + 5'-deoxyadenosine + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Drosophila melanogaster)


name: IAP2:BEN:UEV1A E3 ligase complex auto-ubiquitinates (Drosophila melanogaster)


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Caenorhabditis elegans)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  upon TLR7/8 or 9 activation (Homo sapiens)


name: 4-amino-5-hydroxy-3-all-trans-hexaprenylbenzoate + 5 H(+) + O2 + 4 reduced [2Fe-2S]-[ferredoxin] => 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + NH4(+) + 4 oxidized [2Fe-2S]-[ferredoxin]


name: GUCY2C trimer binds GUCA2A,B (Homo sapiens)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Bos taurus)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Homo sapiens)


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Rattus norvegicus)


name: CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Caenorhabditis elegans)


name: 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Sus scrofa)


name: L-homoserine <=> 2-aminobut-2-enoate + H2O


name: a hydroperoxy polyunsaturated fatty acid + 2 glutathione => a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O


name: (S)-lactate + H(+) + pyruvate => 2,4-didehydro-3-deoxy-L-rhamnonate + H2O


name: sphinganine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoylsphinganine


name: UDP-alpha-D-galactose(in) + UDP-alpha-D-glucose(out) = UDP-alpha-D-galactose(out) + UDP-alpha-D-glucose(in)


name: Cleaved fibrinogen products bind TLR4:LY96 (Rattus norvegicus)


name: TRPs transport extracellular Ca2+ to cytosol (Xenopus tropicalis)


name: WNT ligands traffic to the plasma membrane (Caenorhabditis elegans)


name: FUNDC1 is phosphorylated by CK2 (Dictyostelium discoideum)


name: dimethylamine + H(+) + NADPH + O2 <=> formaldehyde + H2O + methylamine + NADP(+)


name: Retromer recycles WLS to the Golgi (Saccharomyces cerevisiae)


name: 3'-phosphoadenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol <=> 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 2 a ubiquinol + n H(+)(in) + O2 = 2 a ubiquinone + n H(+)(out) + 2 H2O


name: KIR2DL1 interacting with HLA-C group 2 (Cw3) (Homo sapiens)


name: Cho is acetylated to AcCho by CHAT (Caenorhabditis elegans)


name: ST6GALNAC2 transfers sialic acid to Core 1 mucins (Sus scrofa)


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Caenorhabditis elegans)


name: Formation of the SET1B complex (Bos taurus)


name: allantoate + 2 H(+) + 2 H2O = (S)-ureidoglycolate + CO2 + 2 NH4(+)


name: BEGAIN binds DLG2,DLG3,DLG4 (Homo sapiens)


name: beta,beta digalactosyldiacylglycerol galactosyltransferase activity


name: D-glucose + sitosterol => H2O + sitosteryl 3-beta-D-glucoside


name: Translocation of PDGF from ER to Golgi (Caenorhabditis elegans)


name: H2O + N-(9Z-octadecenoyl) ethanolamine => (9Z)-octadecenoate + ethanolamine


name: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) => (6S)-5-formyl-5,6,7,8-tetrahydrofolate(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: all-trans-hexaprenyl diphosphate <=> beta-hexaprene + diphosphate


name: chloroacetaldehyde + H2O + NADP(+) => chloroacetate + 2 H(+) + NADPH


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Bos taurus)


name: Activated FGFR2 binds FRS3 (Drosophila melanogaster)


name: 2 Fe(III)-[cytochrome c] + H2O + pseudooxynicotine <=> 4-oxo-4-(pyridin-3-yl)butanal + 2 Fe(II)-[cytochrome c] + 2 H(+) + methylamine


name: SN-38 + UDP-alpha-D-glucuronate => H(+) + SN-38 O-beta-D-glucuronide + UDP


name: M6PR transports activated ARSA to the lysosome (Mus musculus)


name: butanoate(in) + Na(+)(in) => butanoate(out) + Na(+)(out)


name: chloride + S-adenosyl-L-methionine => chloromethane + S-adenosyl-L-homocysteine


name: Gamma-secretase cleaves NOTCH4 (Homo sapiens)


name: Ub,pS335,S338,T NFE2L2 is degraded (Drosophila melanogaster)


name: 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one + 2 CO2 + 3 CoA => 15-hydroxypentadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: ATP + propanoate <=> ADP + propanoyl phosphate


name: WIP binds WASP,N-WASP, activating them (Homo sapiens)


name: HTR1A binds HTR1A agonists (Danio rerio)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Homo sapiens)


name: Beta-catenin binds SOX proteins (Sus scrofa)


name: HERC2 and PIAS4 are recruited to DNA DSBs (Gallus gallus)


name: Molybdenum ion transfer onto molybdopterin (Canis familiaris)


name: 3-(methylsulfanyl)acryloyl-CoA + reduced [electron-transfer flavoprotein] => 3-(methylsulfanyl)propanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: NEU1 hydrolyses Neu5Ac from glycoconjugates (Canis familiaris)


name: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H2O + methylarsonous acid


name: Interleukin-1 family are secreted (Gallus gallus)


name: Recruitment of SYK to p-FCERI gamma subunit (Sus scrofa)


name: 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H(+) + O2 = bracteatin 6-O-beta-glucoside + H2O


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Bos taurus)


name: AMP + diphosphate + nonanoyl-CoA => ATP + CoA + nonanoate


name: D-glucarate <=> 5-dehydro-4-deoxy-D-glucarate + H2O


name: H(+) + N,N-dihydroxy-L-isoleucine => (1E,2S)-2-methylbutanal oxime + CO2 + H2O


name: glucose + ATP => glucose 6-phosphate + ADP (Gallus gallus)


name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 (Mus musculus)


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR (Rattus norvegicus)


name: (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: (2S)-2-hydroxy-3-methylbutanenitrile => 2-methylpropanal + hydrogen cyanide


name: (1E,2S)-2-methylbutanal oxime + O2 + reduced [NADPH--hemoprotein reductase] => 2-hydroxy-2-methylbutanenitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate = (+)-exo-beta-bergamotene + diphosphate


name: Formation of p-STAT1 homodimer (Xenopus tropicalis)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Homo sapiens)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Caenorhabditis elegans)


name: 7,8-dihydroneopterin 3'-triphosphate + formate + H(+) => GTP + H2O


name: CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Bos taurus)


name: AGK:Mg2+ phosphorylates MAG, DAG (Sus scrofa)


name: solanine UDP-galactose galactosyltransferase activity


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Danio rerio)


name: FAD + H(+) + H2O + squalene <=> FADH2 + hydroxysqualene


name: chloride(out) + L-methionine(out) + 2 Na(+)(out) <=> chloride(in) + L-methionine(in) + 2 Na(+)(in)


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene + A => 1,1'-dihydroxy-3,4-didehydro-1,2-dihydrolycopene + AH2


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)


name: Inactive G alpha (z) reassociates with G beta:gamma (Caenorhabditis elegans)


name: 5alpha-androst-1-ene-3,17-dione + A + H2O => 5alpha-androstan-1,3,17-trione + AH2


name: pro-SFTPB translocates from ER membrane to multivesicle body (Bos taurus)


name: GCK gene expression is inhibited by FOXO1, SIN3A and HDACs (Homo sapiens)


name: ATP + N-acetyl-D-muramate => ADP + H(+) + N-acetyl-alpha-D-muramate 1-phosphate


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-glycerol => 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n CMP + n H(+)


name: H2O + hydroxyacetone + NAD(+) => acetone + H(+) + NADH + O2


name: NT5E:Zn2+ hydrolyses NAD+ (Mus musculus)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA => 3-oxochol-4,6-dien-24-oyl-CoA + H2O


name: (6Z)-octenoyl-CoA + H2O => adenosine 3',5'-bisphosphate + 2 H(+) + S-(6Z-octenoyl)-4'-phosphopantetheine


name: H(+) + UDP-alpha-D-galacturonate <=> CO2 + UDP-beta-L-arabinopyranose


name: NTPDase6 hydrolyzes nucleoside diphosphates (Mus musculus)


name: p-S363,S380,T573 RS6K translocates to the nucleus (Bos taurus)


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Caenorhabditis elegans)


name: H(+) + N(1)-methyladenosine(1408) in 16S rRNA + S-adenosyl-L-homocysteine => adenosine(1408) in 16S rRNA + S-adenosyl-L-methionine


name: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O


name: H2O + hexadecanamide <=> hexadecanoate + NH4(+)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate = goitrin + sulfate


name: 3,4,5-trihydroxybenzoate + H(+) <=> 1,2,3-trihydroxybenzene + CO2


name: Duplex miRNA is loaded into Argonaute (Rattus norvegicus)


name: ATP + Cu(2+)(in) + H2O <=> ADP + Cu(2+)(out) + H(+) + phosphate


name: alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucuronate => beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Canis familiaris)


name: IFNG dimer binds IFNGR (Canis familiaris)


name: FECH binds Fe2+ to PRIN9 to form heme (Saccharomyces cerevisiae)


name: H2O + sphinganine 1-phosphate => phosphate + sphinganine


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Gallus gallus)


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Homo sapiens)


name: guanosine(527) in 16S rRNA + S-adenosyl-L-methionine => N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine


name: D-glucosamine(out) + N(pros)-phospho-L-histidyl-[protein] => D-glucosamine 6-phosphate(in) + L-histidyl-[protein]


name: H2O + N(4)-acetyl-2'-deoxycytidine => 2'-deoxycytidine + acetate + H(+)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Bos taurus)


name: MAT1A multimers transfer Ado from ATP to L-Met (Dictyostelium discoideum)


name: Formation of peptide loading complex (PLC) (Bos taurus)


name: a 7-methoxyisoflavone + H(+) + S-adenosyl-L-homocysteine => a 7-hydroxyisoflavone + S-adenosyl-L-methionine


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + ethanolamine + H(+)


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Bos taurus)


name: SUMOylation of DDX5 with SUMO1 (Schizosaccharomyces pombe)


name: lactate transmembrane transporter activity


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Caenorhabditis elegans)


name: H(+) + H2O2 + L-1-piperideine-6-carboxylate => L-pipecolate + O2


name: AKR1C3 reduces atRAL to atROL (Saccharomyces cerevisiae)


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Homo sapiens)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Bos taurus)


name: (S)-2-amino-6-oxohexanoate + L-alanine => L-lysine + pyruvate


name: H2O + sepiapterin <=> 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+)


name: 9,10-epoxyoctadecanoate + H2O <=> 9,10-dihydroxyoctadecanoate


name: SLC36A4 transports extracellular L-Pro to the cytosol (Xenopus tropicalis)


name: (4Z)-2-oxohept-4-enedioate + H2O <=> (4S)-4-hydroxy-2-oxoheptanedioate


name: dodecanoyl-CoA + hexadecan-1-ol <=> CoA + hexadecanyl dodecanoate


name: FRK phosphorylates PTEN (Canis familiaris)


name: Aquaporin-7 passively transports glycerol out of cell (Schizosaccharomyces pombe)


name: acetyl-CoA + 7 H(+) + 7 malonyl-CoA = 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + 7 CO2 + 8 CoA + 2 H2O


name: (+)-dehydrodiconiferyl acid ketone + a quinol => (+)-dehydrodiconiferyl acid + a quinone


name: cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity


name: H(+)(out) + L-glutamate(out) => H(+)(in) + L-glutamate(in)


name: YME1L1 binds mitochondrial inner membrane proteins (Homo sapiens)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: A + H2O + quinolin-7-ol = 7-hydroxyquinolin-2(1H)-one + AH2


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: ALOX5 oxidises EPA to 5-HEPE (Dictyostelium discoideum)


name: (E)-feruloyl-CoA + H2O => (E)-ferulate + CoA + H(+)


name: BLT receptors can bind LTB4 (Canis familiaris)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Saccharomyces cerevisiae)


name: USP30 deubiquitinates Ub-MOM proteins (Drosophila melanogaster)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Gallus gallus)


name: 1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + a di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H(+)


name: PRKACA phosphorylates TNNI3 (Danio rerio)


name: p-S225-SPHK1 localizes to cytosol (Caenorhabditis elegans)


name: Activation of RAC1 by the PXN:CRK complex (Sus scrofa)


name: Relocalization of nuclearly localized Cyclin D1 to the cytoplasm (Mus musculus)


name: Adenylate cyclase converts ATP into cyclic AMP (Caenorhabditis elegans)


name: LARG binds plexin B1 (Drosophila melanogaster)


name: SLCO4C1 mediates the transport of digoxin (Drosophila melanogaster)


name: C3a receptor binds anaphylatoxin C3a (Canis familiaris)


name: keto-L-sorbose(out) + N(pros)-phospho-L-histidyl-[protein] => L-histidyl-[protein] + L-sorbose 1-phosphate(in)


name: 2 H(+) + O2 + pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-ol


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Homo sapiens)


name: 9,9',15-tri-cis-zeta-carotene + a plastoquinol => 15,9'-di-cis-phytofluene + a plastoquinone


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Sus scrofa)


name: HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Canis familiaris)


name: SARS-CoV-2 nsp3 deISGylates ISGylated IFIH1 (Homo sapiens)


name: abieta-7,13-diene + diphosphate => (+)-copalyl diphosphate


name: NTP Binds Active Site of RNA Polymerase II (Homo sapiens)


name: (E)-6-hydroxyferuloyl-CoA => CoA + scopoletin


name: cytidine 5'-diphosphoramidate + H(+) + L-glutamate => H2O + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Schizosaccharomyces pombe)


name: Beta-catenin migrates to the nucleus (Mus musculus)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Schizosaccharomyces pombe)


name: PNPLA5 hydrolyzes TAG (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] => CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein]


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA


name: RET tyrosine phosphorylation (Mus musculus)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Mus musculus)


name: 17alpha-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP => 17alpha-estradiol + UDP-alpha-D-glucuronate


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine => 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA


name: 1-hexadecanoylglycerone 3-phosphate + heptadecan-1-ol => 1-O-heptadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Caenorhabditis elegans)


name: STAT3 binds activated MET receptor (Caenorhabditis elegans)


name: 2'-O-methyluridine(44) in tRNA(Ser) + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(44) in tRNA(Ser)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)


name: (20S)-ginsenoside Rd + D-glucose => (20S)-ginsenoside Rb1 + H2O


name: ATP + N-hexanoyl-(4R)-hydroxysphinganine <=> ADP + H(+) + N-hexanoyl-(4R)-hydroxysphinganine-1-phosphate


name: L-glutamate 5-semialdehyde <=> (S)-1-pyrroline-5-carboxylate + H(+) + H2O


name: Galactosylation of Pre-NOTCH (Homo sapiens)


name: P2Y6 receptor can bind to UDP (Homo sapiens)


name: Neuromedin-U receptors bind neuromedins U, S (Gallus gallus)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Bos taurus)


name: LIG1 binds POLB at long-patch BER site (Dictyostelium discoideum)


name: (2E)-glutaconyl-CoA + H2O2 => glutaryl-CoA + O2


name: P4HB binds Collagen chains (Rattus norvegicus)


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Danio rerio)


name: NOX4, NOX5 reduce O2 to O2.- (Homo sapiens)


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Xenopus tropicalis)


name: 3 A + phytyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + 3 AH2


name: Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Danio rerio)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Drosophila melanogaster)


name: The receptor:G-protein complex  binds GTP (Xenopus tropicalis)


name: PHB and all-E-10PrP2 are combined into DHB by COQ2 (Drosophila melanogaster)


name: H(+)(out) + N-acetylneuraminate(out) => H(+)(in) + N-acetylneuraminate(in)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Mus musculus)


name: a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH


name: 3-methylcytosine + a 2'-deoxyribose 5'-phosphate in double-stranded DNA + H(+) => an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + H2O


name: (E)-cinnamaldehyde + H2O + O2 = (E)-cinnamate + H(+) + H2O2


name: glycyl-L-glutamine + H2O = glycine + L-glutamine


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-glucosamine <=> beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + H(+) + UDP


name: S-adenosyl-L-homocysteine + trimethylsulfonium => dimethyl sulfide + S-adenosyl-L-methionine


name: RIP3 binds TRIF to mediate necroptosis (Mus musculus)


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Mus musculus)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NAD(+) => 12alpha-hydroxy-3-oxochola-4-en-24-oate + H(+) + NADH


name: a 1,3-diacyl-sn-glycerol + H2O <=> a fatty acid + a monoacylglycerol + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenamide + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + NH4(+)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Xenopus tropicalis)


name: L-rhamnofuranose + NADP(+) = H(+) + L-rhamnono-1,4-lactone + NADPH


name: aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate => D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate


name: H2O + L-homoseryl-tRNA(Lys) <=> H(+) + L-homoserine + tRNA(Lys)


name: (13Z)-docosenoyl-CoA + NADP(+) => (2E,13Z)-docosadienoyl-CoA + H(+) + NADPH


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Canis familiaris)


name: arsenite + 3 glutathione + H(+) = arsenic triglutathione + 3 H2O


name: TNF-α:TNFR1 binds NSMAF (Xenopus tropicalis)


name: Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA <=> 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Danio rerio)


name: BTRC binds p-S344, 347 NFE2L2 (Drosophila melanogaster)


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Drosophila melanogaster)


name: SHP2 binds to the active receptor (Canis familiaris)


name: [(1->4)-beta-D-mannosyl](n) + phosphate = [(1->4)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate


name: SHC1 binds to the phosphorylated EGF receptor:ligand complex (Bos taurus)


name: berkeleydione + CO2 + H2O + succinate => 2-oxoglutarate + berkeleyone B + O2


name: TFIID-class transcription factor complex binding


name: (9Z)-octadecenoate + L-serine => H2O + N-(9Z-octadecenoyl)-L-serine


name: 2 2-iminio-3-(indol-3-yl)propanoate + H2O2 => 2 H2O + indole-3-pyruvate imine dimer


name: intercellular adhesion molecule-3 receptor binding


name: RANBP2 SUMOylates PML with SUMO2 (Homo sapiens)


name: NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Sus scrofa)


name: a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Canis familiaris)


name: YME1L1 proteolyzes unassembled proSMDT1 (Canis familiaris)


name: ADP-alpha-D-glucose + diphosphate => alpha-D-glucose 1-phosphate + ATP + H(+)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Sus scrofa)


name: benzoyl-CoA + hexan-2-ol = CoA + hexan-2-yl benzoate


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Canis familiaris)


name: p-S400-Cot phosphorylates NIK (Saccharomyces cerevisiae)


name: (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate => (6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP


name: L-tetrahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-7-(methylsulfanyl)heptanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Rattus norvegicus)


name: p62 binds ubiquitinated mitochondrial substrates (Caenorhabditis elegans)


name: dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H2O + pheophorbide a <=> C-13(2)-carboxypyropheophorbide a + methanol


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Homo sapiens)


name: PAK1,2,3 phosphorylates MAPK6,4 (Gallus gallus)


name: (S)-lactate + oxaloacetate = (S)-malate + pyruvate


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Canis familiaris)


name: alpha-D-ribose 1-phosphate <=> D-ribose 5-phosphate


name: 4-methylpent-3-en-1-yl acetate + H2O + NADP(+) => H(+) + NADPH + O2 + sulcatone


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Bos taurus)


name: an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol = 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: SH2 domain of Src binds to the active receptor (Homo sapiens)


name: DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function (Canis familiaris)


name: [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + [eIF5A protein]-L-lysine <=> [deoxyhypusine synthase]-L-lysine + [eIF5A protein]-N-(4-aminobutylidene)-L-lysine


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Caenorhabditis elegans)


name: MK2 phosphorylates BRF1 (Caenorhabditis elegans)


name: H2O + NAD(+) <=> AMP + beta-nicotinamide D-ribonucleotide + 2 H(+)


name: H2O2 + tetradecanoate = (2R)-hydroxytetradecanoate + H2O


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Caenorhabditis elegans)


name: ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Rattus norvegicus)


name: 10-hydroxy-alpha-humulene + NAD(+) = H(+) + NADH + zerumbone


name: Translocation of tBID to mitochondria (Rattus norvegicus)


name: H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine => pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Canis familiaris)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Mus musculus)


name: IL3 gene transcription is stimulated by RUNX1 and ELF1 (Homo sapiens)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Canis familiaris)


name: ornithine => putrescine + CO2 (Bos taurus)


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Gallus gallus)


name: Factor H binds host cell surface markers (Canis familiaris)


name: ATP + L-serine <=> ADP + H(+) + O-phospho-L-serine


name: IL37:IL18R1 binds SIGIRR (Canis familiaris)


name: L-ascorbate + O2 + tyramine => (R)-octopamine + H2O + L-dehydroascorbate


name: CO2 + itaconate => H(+) + trans-aconitate


name: choloyl-CoA + H2O => cholate + CoA + H(+)


name: 2 H(+)(in) + L-aspartate(in) => 2 H(+)(out) + L-aspartate(out)


name: 2-glutathionyl-2-methylbut-3-enal + H(+) + NADH => 2-glutathionyl-2-methylbut-3-en-1-ol + NAD(+)


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Bos taurus)


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Drosophila melanogaster)


name: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA


name: N-acetylserotonin + S-adenosyl-L-methionine => H(+) + melatonin + S-adenosyl-L-homocysteine


name: HYAL1 hydrolyses Chondroitin chains (Xenopus tropicalis)


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Caenorhabditis elegans)


name: 2-oxoglutarate + methylphosphonate + O2 <=> CO2 + hydroxymethylphosphonate + succinate


name: dGMP + H2O <=> 2'-deoxyguanosine + phosphate


name: 3alpha(S)-strictosidine + H2O = secologanin + tryptamine


name: H(+) + N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: D-xylotriose + O2 => D-xylotriono-1,5-lactone + H2O2


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) = 6-lactoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH


name: SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Drosophila melanogaster)


name: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) <=> 2,3-dihydroxybenzoate + H(+) + NADH


name: CoA + H(+) + N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein] => N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Homo sapiens)


name: ING2 recruits EP300 to TP53 (Mus musculus)


name: dodecanal + NADP(+) => (2E)-dodecenal + H(+) + NADPH


name: B3GNT5 transfers GlcNAc to LacCer (Sus scrofa)


name: asperterpenoid B + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => asperterpenoid A + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Schizosaccharomyces pombe)


name: Cyclisation of GTP to precursor Z (Canis familiaris)


name: MMP14 (MT1-MMP) binds TIMP2 (Danio rerio)


name: 2-aminopentane + H2O + NAD(+) => H(+) + NADH + NH4(+) + pentan-2-one


name: 2xPDXK:2xZn2+ phosphorylates PXL (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in)


name: ATP + H2O + sitosterol(in) <=> ADP + H(+) + phosphate + sitosterol(out)


name: FUT1,2 transfer fucose to gangliosides (Caenorhabditis elegans)


name: formyl-CoA + succinate => formate + succinyl-CoA


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Caenorhabditis elegans)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: H2O + oxidized 2[4Fe-4S]-[ferredoxin] + pentalenate => 1-deoxypentalenate + 2 H(+) + O2 + reduced 2[4Fe-4S]-[ferredoxin]


name: sucrose + UDP-alpha-D-galactose => H(+) + loliose + UDP


name: a 1-acyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) => a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2


name: p14ARF forms a ternary complex with MDM2 and TP53 (Homo sapiens)


name: B4GALTs transfer Gal to the N-glycan precursor (Canis familiaris)


name: ADP + H(+) + thiamine diphosphate <=> adenosine thiamine triphosphate + phosphate


name: Autophosphorylation of PDGF alpha/beta receptors (Gallus gallus)


name: USP3,SAGA deubiquitinate Histone H2A,H2B (Mus musculus)


name: (4R)-hydroxysphinganine + 2-hydroxyhexacosanoyl-CoA = CoA + H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: n H(+)(out) + spermine(in) => n H(+)(in) + spermine(out)


name: Formation of the CE:GMP intermediate complex (Xenopus tropicalis)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Rattus norvegicus)


name: Association of HA into rafts (Homo sapiens)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Dictyostelium discoideum)


name: Fe-coproporphyrin III + 2 H(+) + 2 H2O2 = 2 CO2 + 4 H2O + heme b


name: "hydrogen peroxide-dependent heme synthase"


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine => 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: SENP1,2,5 proteolytically process SUMO2 (Drosophila melanogaster)


name: (8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O => (8R,9R)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: glyoxal + L-cysteinyl-[protein] <=> S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein]


name: Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Canis familiaris)


name: Passive I- efflux mediated by SMCT1 (Sus scrofa)


name: GLI proteins bind CDC73 (Rattus norvegicus)


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)


name: H2O + hypoxanthine + O2 <=> H2O2 + xanthine


name: H2O + triphosphate <=> diphosphate + phosphate


name: GAPDH tetramers reduce 1,3BPG to GA3P (Mus musculus)


name: G13 activation by TP receptor (Danio rerio)


name: n H(+)(in) + taurocholate(in) => n H(+)(out) + taurocholate(out)


name: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate <=> cyclic pyranopterin phosphate + diphosphate


name: Dephosphorylation of p107 (RBL1) by PP2A (Mus musculus)


name: GOT2 dimer deaminates L-Asp (Schizosaccharomyces pombe)


name: PDE3A inhibitors bind PDE3A (Homo sapiens)


name: (2E)-geranyl diphosphate + isopentenyl diphosphate = (2E,6E)-farnesyl diphosphate + diphosphate


name: GMP(in) + NAD(+)(out) <=> GMP(out) + NAD(+)(in)


name: acetyl-CoA + tyramine => CoA + H(+) + N-acetyltyramine


name: 2-chloro-6-nitrotoluene + NADH + O2 => 4-chloro-3-methylcatechol + NAD(+) + nitrite


name: (S)-eriodictyol + S-adenosyl-L-methionine => (S)-homoeriodictyol + H(+) + S-adenosyl-L-homocysteine


name: PIP3 binds to RhoA and activates it (Mus musculus)


name: CMBL hydrolyses OM to OLMS (Rattus norvegicus)


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin => 2-hydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Rattus norvegicus)


name: 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine => 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine + ethanolamine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + L-serine


name: L-ornithine + NADPH + O2 <=> H2O + N(5)-hydroxy-L-ornithine + NADP(+)


name: ZIP6 and ZIP14 mediate zinc influx into cells (Drosophila melanogaster)


name: H(+)(out) + melibiose(out) => H(+)(in) + melibiose(in)


name: ALOX5 oxidises DHA to 7-HDHA (Sus scrofa)


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Bos taurus)


name: ADP + beta-D-fructose 1,6-bisphosphate + H(+) => ATP + beta-D-fructose 6-phosphate


name: cytidine(2499) in 23S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(2499) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Drosophila melanogaster)


name: Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)


name: dihydrochelirubine + NAD(+) = chelirubine + NADH


name: GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate <=> GDP + H(+) + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: 3beta-hydroxy-chol-5-ene-24-oyl-CoA + A => 3beta-hydroxy-chol-5,22-dien-24-oyl-CoA + AH2


name: 4-hydoxytryptamine 4-phosphate + 2 S-adenosyl-L-methionine => 2 H(+) + psilocybin + 2 S-adenosyl-L-homocysteine


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADH


name: ADP + H(+) + O-phospho-L-seryl-[tau protein] => ATP + L-seryl-[tau protein]


name: AP2 binds chlorpromazine (Rattus norvegicus)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Canis familiaris)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Sus scrofa)


name: 7,8-dihydropteroate + diphosphate => (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate


name: 3-oxobutanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxybutanoyl-[ACP] + NADP(+)


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Sus scrofa)


name: G protein-coupled nucleotide receptor activity


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Bos taurus)


name: ATP + glutathione(in) + glycodeoxycholate(in) + H2O = ADP + glutathione(out) + glycodeoxycholate(out) + H(+) + phosphate


name: SUMOylation of RARA with SUMO2 (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + estrone 3-O-(beta-D-glucuronate) => adenosine 3',5'-bisphosphate + estrone 3-O-(3-sulfo-beta-D-glucuronate) + H(+)


name: trans-Golgi Network Coat Assembly (Drosophila melanogaster)


name: Interleukin-35 translocates from the ER lumen to the extracellular region (Bos taurus)


name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex (Danio rerio)


name: CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine => 4-coumaroyl-CoA + S-adenosyl-L-methionine


name: Succinate <=> Fumarate (with FAD redox reaction on enzyme) (Xenopus tropicalis)


name: 4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity


name: di-(9Z)-octadecenoylglycerol + H2O => (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+)


name: HuR binds the CRM1 nuclear export machinery (Sus scrofa)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Bos taurus)


name: cytidine(3782) in 28S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(3782) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Xenopus tropicalis)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Caenorhabditis elegans)


name: all-trans-beta-carotene + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-zeaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Homo sapiens)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O = 14betaH-scalarane-17alpha-19-diol


name: ATP + L-valine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate = ADP + dapdiamide A + H(+) + phosphate


name: E1 mediated ubiquitin activation (Sus scrofa)


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Rattus norvegicus)


name: ribonucleotidyl-uridine-RNA <=> a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-uridine-RNA


name: [6)-beta-D-fructofuranosyl-(2->](n) alpha-D-glucopyranoside + sucrose = [6)-beta-D-fructofuranosyl-(2->](n+1) alpha-D-glucopyranoside + D-glucose


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Bos taurus)


name: ATP + UDP-N-acetyl-alpha-D-glucosamine = ADP + H(+) + UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate


name: 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + zealexin A1 => (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced [NADPH--hemoprotein reductase]


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: ALDH2 transforms GTN to NO (Homo sapiens)


name: p-Y-STAT3 binds p-STAT5 (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate <=> (E)-beta-ocimene + diphosphate


name: MSH2:MSH3 binds insertion/deletion loop of 2 bases or more (Sus scrofa)


name: L-alanine(in) + L-cysteine(out) <=> L-alanine(out) + L-cysteine(in)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Xenopus tropicalis)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Homo sapiens)


name: (4S)-4-hydroxy-2-oxoglutarate => glyoxylate + pyruvate


name: [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate + NADP(+) => [4-(6-methylheptanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate + H(+) + NADPH


name: (22S)-22-hydroxycampesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => campesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: ANOs transport cytosolic Cl- to extracellular region (Dictyostelium discoideum)


name: (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) (Xenopus tropicalis)


name: Beta-catenin recruits CDC73 and LEO1 (Sus scrofa)


name: a C27-steroid + O2 + reduced [NADPH--hemoprotein reductase] = a (22S)-22-hydroxy C27-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + N(1)-methylpseudouridine(54) in tRNA + S-adenosyl-L-homocysteine => pseudouridine(54) in tRNA + S-adenosyl-L-methionine


name: 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP = AMP + diphosphate + H(+) + staphyloferrin B


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Xenopus tropicalis)


name: (2S,3S)-versiconal hemiacetal acetate + H2O => (2S-3S)-versiconal hemiacetal + acetate + H(+)


name: D-glucose + D-glucose 6-phosphate => alpha-maltose 6'-phosphate + H2O


name: (3R)-3-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)


name: lithocholate + NADP(+) => 3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine => diphosphate + XMP


name: Caspase-6 translocates to the nucleus (Gallus gallus)


name: ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA (Caenorhabditis elegans)


name: Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)


name: GBA2 hydrolyzes GlcCer (plasma membrane) (Canis familiaris)


name: UBXN1 binds BRCA1:BARD1 heterodimer (Mus musculus)


name: D-cycloserine(in) + H(+)(in) <=> D-cycloserine(out) + H(+)(out)


name: D-galactose + O2 => D-galactono-1,5-lactone + H2O2


name: (2R,3S)-iso(homo)3citrate => cis-(homo)3aconitate + H2O


name: SERPINB13 binds cathepsin L (Sus scrofa)


name: CO + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] <=> CO2 + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: L-aspartate 4-semialdehyde + pyruvate => (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Mus musculus)


name: CCNA2 gene expression is inhibited by RBL1 and RBL2 (Homo sapiens)


name: TDO tetramer dioxygenates L-Trp to NFK (Danio rerio)


name: 2 alpha,alpha'-trehalose 6-mycolate => alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose


name: KMT2A (MLL) binds RUNX1 (Drosophila melanogaster)


name: L-Glutamine transport into neurons (Gallus gallus)


name: allantoate + 2 H(+) + 2 H2O => (S)-ureidoglycolate + CO2 + 2 NH4(+)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Gallus gallus)


name: acetyl-CoA + L-methionine sulfoximine <=> CoA + H(+) + N-acetyl-L-methionine sulfoximine


name: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate => 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)


name: glycyl-L-proline + H2O = glycine + L-proline


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Canis familiaris)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Xenopus tropicalis)


name: all-trans-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + all-trans-retinal


name: G-protein alpha subunit is inactivated (Danio rerio)


name: cGMP binds CNG channel to form cGMP:CNG channel (Gallus gallus)


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Bos taurus)


name: p-T68-CHEK2 autophosphorylates (Saccharomyces cerevisiae)


name: 16alpha-hydroxyestrone + UDP-alpha-D-glucuronate = 16alpha-hydroxyestrone 16-O-(beta-D-glucuronate) + H(+) + UDP


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Drosophila melanogaster)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-GDP => GDP + H(+) + lactate


name: PTPRJ dephosphorylates MET (Canis familiaris)


name: Photons induce isomerization of 11c-retinyl to at-retinyl (Mus musculus)


name: indole-3-carbonyl nitrile + O2 + reduced [NADPH--hemoprotein reductase] <=> 4-hydroxy-indole-3-carbonyl nitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC46A1 transports hemes from extracellular region to cytosol (Canis familiaris)


name: amicoumacin A 2-phosphate + H2O = amicoumacin A + phosphate


name: 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O => (9Z,12Z)-octadecadienoate + glycerol + H(+)


name: IL37(?-218) translocates from the cytosol to the nucleus (Xenopus tropicalis)


name: ATP + N-acetyl-D-hexosamine = ADP + H(+) + N-acetyl-alpha-D-hexosamine 1-phosphate


name: beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-seryl-[protein] => H2O + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein]


name: 4-guanidinobutanal + CO2 => 5-guanidino-2-oxopentanoate + H(+)


name: a dicarboxylate(in) + prostaglandin F2alpha(out) <=> a dicarboxylate(out) + prostaglandin F2alpha(in)


name: 15-methylhexadecasphing-4-enine + phosphate => 15-methylhexadecasphing-4-enine 1-phosphate + H2O


name: The receptor:G-protein complex dissociates (Mus musculus)


name: CBL ubiquitinates FRS2 and FGFR1 (Homo sapiens)


name: NADP(+) + propanoyl-CoA => acryloyl-CoA + H(+) + NADPH


name: Spontaneous hydrolysis of C3 thioester (Homo sapiens)


name: benzoyl-CoA + butan-1-ol = butyl benzoate + CoA


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + ATP => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+)


name: 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H2O + NADP(+) => 4-hydroxy-3-[(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-2-one + H(+) + NADPH + O2


name: ADP + H(+) + NADPH + phosphate => (6S)-NADPHX + ATP


name: p-MII:SAG dissociates to p-RHO and SAG (Homo sapiens)


name: 12-(9Z-hexadecenoyloxy)-octadecanoate + H2O <=> (9Z)-hexadecenoate + 12-hydroxyoctadecanoate + H(+)


name: 19-hydroxytestosterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 19-oxotestosterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: nucleobase-containing compound transmembrane transporter activity


name: Binding of APOBEC-1 to form editosome (Bos taurus)


name: ADP(out) + dADP(in) => ADP(in) + dADP(out)


name: MMP14:TIMP2 binds proMMP2 (Caenorhabditis elegans)


name: p-PKR dimer phosphorylates ILF3:ILF2 (Homo sapiens)


name: PDE6D dissociates from ARL13B:INPP5E (Gallus gallus)


name: acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein]


name: (S)-4-hydroxymandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-hydroxyphenylacetonitrile + O2 + reduced [NADPH--hemoprotein reductase]


name: DYRK2 phosphorylates TP53 (Rattus norvegicus)


name: an anthocyanidin 3,5-di-O-beta-D-glucoside + 2 H(+) + UDP => an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose


name: K+-independent Li+/Ca2+ exchanger transport (Caenorhabditis elegans)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Xenopus tropicalis)


name: (-)-lariciresinol + H(+) + NADPH => (+)-secoisolariciresinol + NADP(+)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Rattus norvegicus)


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + acetyl-CoA => 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + H(+)


name: Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Rattus norvegicus)


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Mus musculus)


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Sus scrofa)


name: prunetin + UDP-alpha-D-glucuronate = prunetin-5-O-beta-D-glucuronide + UDP


name: (R)-2-hydroxypropyl-coenzyme M <=> (R)-1,2-epoxypropane + coenzyme M


name: L-glutamine(out) + L-threonine(in) + Na(+)(out) <=> L-glutamine(in) + L-threonine(out) + Na(+)(in)


name: (2-aminoethyl)phosphonate + acetyl-CoA = (2-acetamidoethyl)phosphonate + CoA + H(+)


name: (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone => (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol


name: Dissociation of L13a from the 60s ribosomal subunit (Bos taurus)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Sus scrofa)


name: kainate receptor binds glutamate (Canis familiaris)


name: ARHGAP35 stimulates RHOA GTPase activity (Bos taurus)


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H(+) + NADPH = (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: (6S)-NADHX + ATP = ADP + H(+) + NADH + phosphate


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Danio rerio)


name: 4 glutathione + 2 H(+) + selenite <=> glutathione disulfide + 3 H2O + selenodiglutathione


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Sus scrofa)


name: a sterol ester + CoA => a long-chain fatty acyl-CoA + a sterol


name: PLEKHA3,8 bind PI4P, ARF1 (Homo sapiens)


name: H(+) + N-hexacosanoylsphinganine + NADPH + O2 <=> H2O + N-(2-hydroxyhexacosanoyl)-sphinganine + NADP(+)


name: a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: L-lysine + NAD(+) <=> Delta(1)-piperideine-2-carboxylate + H(+) + NADH + NH4(+)


name: TRPV1 binds TRPV1 agonists (Canis familiaris)


name: ITPA hydrolyses ITP to IMP (Dictyostelium discoideum)


name: α1-agonists bind ADRA1A,B,D (Gallus gallus)


name: (2E)-eicosenoyl-CoA + FADH2 => eicosanoyl-CoA + FAD + H(+)


name: 2,6-dioxo-6-phenylhexa-3-enoate + H2O => 2-oxopent-4-enoate + benzoate + H(+)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Canis familiaris)


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Drosophila melanogaster)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Drosophila melanogaster)


name: (2R)-2-phosphoglycerate + ADP + H(+) => (R)-glycerate + ATP


name: PREDL:ALB dissociates (Rattus norvegicus)


name: Phosphorylated AKT1S1:mTORC1 binds YWHAB (Caenorhabditis elegans)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Danio rerio)


name: CETP-mediated lipid exchange: LDL gains cholesterol ester (Homo sapiens)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Xenopus tropicalis)


name: (2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (S)-malate(in) + succinate(out) <=> (S)-malate(out) + succinate(in)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: 3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)


name: TRAIL:TRAIL receptor trimers bind FADD (Homo sapiens)


name: lipoxin A4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-lipoxin A4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-2-benzylsuccinate + succinyl-CoA => (S)-2-benzylsuccinyl-CoA + succinate


name: PAOX:FAD oxidises NASPN to SPM (Bos taurus)


name: Basigin binds Mannose-carrying cell recognition molecules (Drosophila melanogaster)


name: USP5 cleaves polyubiquitin (Drosophila melanogaster)


name: acetate + 2 H(+) + precorrin-6A + S-adenosyl-L-homocysteine => H2O + precorrin-5 + S-adenosyl-L-methionine


name: 1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Bos taurus)


name: Dopa is decarboxylated to dopamine (Rattus norvegicus)


name: p-Y389,400-RUFY1 binds PI3P (Xenopus tropicalis)


name: WLS dissociates from retromer (Xenopus tropicalis)


name: (9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + UDP-alpha-D-glucose => (9Z)-17-hydroxyoctadec-9-enoate 17-O-sophoroside + H(+) + UDP


name: 7(1)-hydroxychlorophyllide a + H2O + NADP(+) => chlorophyllide a + H(+) + NADPH + O2


name: Addition of nucleotides between position +11 and +30 (Bos taurus)


name: SGSH hydrolyses Heparan sulfate chain(2) (Sus scrofa)


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Canis familiaris)


name: Antizyme OAZ binds to Ornithine decarboxylase (Mus musculus)


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Gallus gallus)


name: (indol-3-yl)acetate + succinyl-CoA => (indol-3-yl)acetyl-CoA + succinate


name: 5 H(+) + 4 H2O + 2 L-citrulline + 2 nitric oxide + 3 oxidized [flavodoxin] => 2 L-arginine + 4 O2 + 3 reduced [flavodoxin]


name: XIAP dissociates from ub-TLE (Canis familiaris)


name: Intrinsic nucleotide exchange on RAS (Drosophila melanogaster)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Sus scrofa)


name: 3beta,20alpha-dihydroxy-5beta-pregnane + NADP(+) => 3beta-hydroxy-5beta-pregnane-20-one + H(+) + NADPH


name: α1-agonists bind ADRA1A,B,D (Sus scrofa)


name: 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate + N-acetyl-beta-D-galactosamine => 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc + H2O


name: (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + monacolin J carboxylate <=> holo-[2-methylbutanoate polyketide synthase] + lovastatin carboxylate


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+) => Fe(III)-di(C-5-deoxy-beta-D-glucosyl)-enterobactin + H2O


name: USP1:WDR48 binds monoUb:K164-PCNA (Sus scrofa)


name: acetyl-CoA + choline <=> acetylcholine + CoA


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Dictyostelium discoideum)


name: Membrane-bound GISH binds to ARR receptor complex (Drosophila melanogaster)


name: PLC beta-mediated PIP2 hydrolysis (Drosophila melanogaster)


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Danio rerio)


name: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol


name: NADP(+) + tetradecasphinganine = 3-oxotetradecasphinganine + H(+) + NADPH


name: (2S)-3-sulfopropanediol + NAD(+) = (2S)-3-sulfolactaldehyde + H(+) + NADH


name: Dephosphorylation of PAG by SHP2 (Xenopus tropicalis)


name: estrone 3-sulfate(out) + H(+)(in) => estrone 3-sulfate(in) + H(+)(out)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + heptadecanoyl-CoA + O2 <=> (9Z)-heptadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Activation of EPACs by cAMP (Canis familiaris)


name: Loading of dopamine into synaptic veiscles (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Canis familiaris)


name: USP7 deubiquitinates TP53 and counteracts MDM2 (Sus scrofa)


name: 3-hydroxydodecanoyl-CoA + H2O = 3-hydroxydodecanoate + CoA + H(+)


name: Phosphorylation and activation of Ezrin (Bos taurus)


name: dimethylallyl diphosphate + neoechinulin B => diphosphate + isoechinulin B


name: ADIPOQ trimer binds ADIPOR dimers (Rattus norvegicus)


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + H(+) + hexadecanoate


name: RNA Pol II initiates transcription from damaged DNA template (Gallus gallus)


name: (9Z,12Z)-octadecadienoate + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H(+) => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + eicosanoyl-CoA <=> 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Homo sapiens)


name: CoA + H(+) + N(6)-acetyl-L-lysyl-[beta-tubulin] => acetyl-CoA + L-lysyl-[beta-tubulin]


name: diphosphate + taxa-4,11-diene => (2E,6E,10E)-geranylgeranyl diphosphate


name: Y693-STAT4 dimer translocates to the nucleus (Homo sapiens)


name: 2-oxoglutarate + L-asparagine <=> 2-oxosuccinamate + L-glutamate


name: (2R)-3-phosphoglycerate + GTP = (2R)-3-phospho-glyceroyl phosphate + GDP


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: NCOA1 recruits EP300 to TGFA promoter (Rattus norvegicus)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: LTA4 is converted to LTC4 by LTC4S (Canis familiaris)


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Rattus norvegicus)


name: Activation of Calcineurin (Schizosaccharomyces pombe)


name: a sphingomyelin + CMP + H(+) => an N-acylsphing-4-enine + CDP-choline


name: Hh-Np traffics to the plasma membrane (Xenopus tropicalis)


name: 2-hydroxydodecanoate + H2O2 <=> 2,3-dihydroxydodecanoate + H2O


name: beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-D-glucose + GDP + H(+) => GDP-beta-L-fucose + lactose


name: 2 a ubiquinone + H2O + phenylacetyl-CoA => 2 a ubiquinol + phenylglyoxylyl-CoA


name: SUMOylation of HIPK2 with SUMO1 (Caenorhabditis elegans)


name: cadaverine(in) + H(+)(in) = cadaverine(out) + H(+)(out)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Sus scrofa)


name: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Gallus gallus)


name: GLI proteins bind CDC73 (Drosophila melanogaster)


name: factor XII -> factor XIIa (Rattus norvegicus)


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Mus musculus)


name: 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: 3-oxononanoyl-[ACP] + H(+) + NADPH = (3R)-hydroxynonanoyl-[ACP] + NADP(+)


name: a 16alpha-hydroxysteroid + NAD(+) => a 16-oxosteroid + H(+) + NADH


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Bos taurus)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Canis familiaris)


name: PGH2 is isomerised to PGD2 by PTGDS (Drosophila melanogaster)


name: COX10 transforms heme to heme O (Dictyostelium discoideum)


name: Cleaved KMT2A dimers translocate to the nucleus (Drosophila melanogaster)


name: a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Bos taurus)


name: coenzyme M + methyl-Co(III)-[methylated-thiol-specific corrinoid protein] = Co(I)-[methylated-thiol-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: (-)-2'-epi-GR24 + H2O = (-)-2'-epi-GR24 ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one


name: Arachidonic acid is converted to HXA3/B3 by ALOX12 (Homo sapiens)


name: 3,4-dihydroxyphenylacetate + chloride + NAD(+) => 4-chlorophenylacetate + NADH + O2


name: Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Bos taurus)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Canis familiaris)


name: (R)-S-lactoylglutathione + H2O <=> (R)-lactate + glutathione + H(+)


name: 2 hydrogencarbonate(out) + sulfate(in) => 2 hydrogencarbonate(in) + sulfate(out)


name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Danio rerio)


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)


name: (2E)-hexadecenedioyl-CoA + H2O <=> (3R)-hydroxyhexadecanedioyl-CoA


name: dimethyl sulfone + FMNH2 + O2 <=> FMN + formaldehyde + 2 H(+) + H2O + methanesulfinate


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Danio rerio)


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Homo sapiens)


name: PDK isoforms phosphorylate lipo-PDH (Xenopus tropicalis)


name: macrocin + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + tylosin


name: (2E)-geranyl diphosphate + esculetin = 8-geranylesculetin + diphosphate


name: HSF1 trimer translocates to the nucleus (Homo sapiens)


name: A1 and A3 receptors bind adenosine (Sus scrofa)


name: H2O + N-formimidoyl-L-aspartate <=> N-formyl-L-aspartate + NH4(+)


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + valerianol


name: CES2 hydrolyzes ASA- (Caenorhabditis elegans)


name: D-altronate => 2-dehydro-3-deoxy-D-gluconate + H2O


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 17alpha-hydroxywithaferin A + UDP-alpha-D-glucose => 17alpha-sitoindoside IX + H(+) + UDP


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate => (+)-exo-beta-bergamotene + diphosphate


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP + CoA => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: LGI3 binds ADAM22,23,synatxin1 (Homo sapiens)


name: KIT mutants bind type I TKIs (Homo sapiens)


name: Phosphorylated CACT and DL/DIF dimer dissociate from the TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)


name: RAC3 translocates to the endoplasmic reticulum membrane (Gallus gallus)


name: acetyl-CoA + ATP + hydrogencarbonate = ADP + H(+) + malonyl-CoA + phosphate


name: TTPA binds alpha-TOH (Drosophila melanogaster)


name: DELE1(143-515) binds EIF2AK1 (HRI) (Xenopus tropicalis)


name: oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor


name: demethylsuberosin + O2 + reduced [NADPH--hemoprotein reductase] => (7S)-marmesin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MeSeOH is reduced to MeSeH by TXNRD1 (Rattus norvegicus)


name: adenosine 5'-phosphosulfate + ATP => 3'-phosphoadenylyl sulfate + ADP + H(+)


name: Syndecans 1, 2 & 4 bind VTN (Canis familiaris)


name: ATP + L-glutamate + tyramine = ADP + gamma-L-glutamyltyramine + H(+) + phosphate


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Activated JNK phosphorylates c-JUN (Homo sapiens)


name: a ganglioside GM2 (d18:1(4E)) + H2O => a ganglioside GM3 (d18:1(4E)) + N-acetyl-beta-D-galactosamine


name: a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate + H(+)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Xenopus tropicalis)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Canis familiaris)


name: Transfer of ISG15 from E1 to E2 (UBCH8) (Rattus norvegicus)


name: STAT5 is recruited by JAK2 (Rattus norvegicus)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: ATP + H2O + L-aspartate + L-glutamine <=> AMP + diphosphate + H(+) + L-asparagine + L-glutamate


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Rattus norvegicus)


name: a 2,3-saturated fatty acid + H2O2 = a 3-hydroxy fatty acid + H2O


name: a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: Activated PKC-alpha  activate MMP3 (Homo sapiens)


name: p-STAT3 dissociates from TSLP:IL7R:CRLF2:p-STAT3 complex (Canis familiaris)


name: UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Homo sapiens)


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Xenopus tropicalis)


name: Furin cleaves pro-prothrombin to prothrombin (Canis familiaris)


name: 3beta-hydroxy-5beta-pregnane-20-one + H(+) + NADPH => 3beta,20alpha-dihydroxy-5beta-pregnane + NADP(+)


name: Activation of Ca2+ activated Potassium channels with small conductance (Sus scrofa)


name: GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS (Homo sapiens)


name: (11R)-carlactone + O2 + reduced [NADPH--hemoprotein reductase] = (11R)-19-hydroxycarlactone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Drosophila melanogaster)


name: Autophosphorylation of PDGF alpha/beta receptors (Xenopus tropicalis)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Homo sapiens)


name: RTP1S:RTP2:underrepresented Olfactory Receptor translocates from the endoplasmic reticulum membrane to the plasma membrane (Homo sapiens)


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Bos taurus)


name: Cleavage of DFF45 (224) by caspase-3 (Danio rerio)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP => 1D-myo-inositol hexakisphosphate + ATP


name: lyso-ornithine lipid acyltransferase activity


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Rattus norvegicus)


name: Caspase-mediated cleavage of E-Cadherin (Canis familiaris)


name: Recruitment and activation of Chk1 (Drosophila melanogaster)


name: (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Danio rerio)


name: methanofuran + N(5)-formyl-5,6,7,8-tetrahydromethanopterin => 5,6,7,8-tetrahydromethanopterin + H(+) + N-formylmethanofuran


name: acetyl-CoA + H(+) + NADH => acetaldehyde + CoA + NAD(+)


name: K63polyUb-IRAK1 dissociates (Drosophila melanogaster)


name: Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Rattus norvegicus)


name: (+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Loading of antigenic peptides on to class I MHC (Canis familiaris)


name: all-trans-10'-apo-beta-carotenal + O2 => 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + beta-ionone


name: SUMOylation of Histone H4 with SUMO1 (Dictyostelium discoideum)


name: pro-SFTPC translocates from ER membrane to multivesicle body (Gallus gallus)


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Drosophila melanogaster)


name: RHOC GAPs stimulate RHOC GTPase activity (Bos taurus)


name: LONP1 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: N-(9Z-octadecenoyl) ethanolamine + phosphate => H2O + N-(9Z-octadecenoyl)-ethanolamine phosphate


name: Autocatalytic phosphorylation of FGFR1c (Bos taurus)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA <=> 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: (E)-hex-2-enal + hydrogen cyanide <=> (2S,3E)-2-hydroxyhept-3-enenitrile


name: H(+) + meso-2,6-diaminoheptanedioate <=> CO2 + L-lysine


name: PEX19:class I PMP binds PEX3 (Schizosaccharomyces pombe)


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Homo sapiens)


name: MARK4 binds ODF2 in the centriole (Canis familiaris)


name: CES1trimer hydrolyses ACEI pro-drugs to ACEIs (Sus scrofa)


name: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 24-methylenecycloartanol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: (2E)-but-2-enoyl-AMP + holo-[ACP] <=> (2E)-butenoyl-[ACP] + AMP + H(+)


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Canis familiaris)


name: a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose 6-phosphate + H(+)


name: RAC2 translocates to the mitochondrial membrane (Gallus gallus)


name: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O => (7R)-7-aminocephalosporanate + glutarate


name: 3-(all-trans-hexaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine => 2-methoxy-6-(all-trans-hexaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Drosophila melanogaster)


name: PARVB/Affixin interacts with alpha PIX (Homo sapiens)


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] => akuammicine + formate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Slo3 Potassium Transport (Plasmodium falciparum)


name: H2O + kynurenate + L-tryptophan => indole-3-pyruvate + L-kynurenine


name: 4alpha-methyl-5alpha-cholest-8-en-3-one + H(+) + NADPH => 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+)


name: alpha-D-glucose 1-phosphate + alpha-maltotetraose => alpha-maltopentaose + phosphate


name: CD59 inhibits MAC formation (Mus musculus)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b (Rattus norvegicus)


name: N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine


name: ADP-L-glycero-beta-D-manno-heptose + L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) => ADP + H(+) + L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: Dissociation of the P2Y purinoceptor 1:Gq complex (Mus musculus)


name: CSNK1A1 phosphorylates SMO dimer (Homo sapiens)


name: Parathyroid hormone receptor can bind parathyroid hormone (Bos taurus)


name: L-arabinitol + NAD(+) = H(+) + L-ribulose + NADH


name: H(+) + isopentadecanoyl-CoA + L-serine = 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA


name: NAD(+) + taurochenodeoxycholate <=> 7-oxotaurolithocholate + H(+) + NADH


name: long-chain fatty acid-CoA ligase activity


name: Coumarin is 7-hydroxylated by CYP2A6 (Dictyostelium discoideum)


name: (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + CO2 + pyruvate + succinate


name: Elongation of Extended Telomeric Chromosome End (Canis familiaris)


name: PON1,3 hydrolyse ATVL to ATV (Homo sapiens)


name: Lsm1-7 Complex binds deadenylated mRNA (Dictyostelium discoideum)


name: cAMP hydrolysis by Cam-PDE 1 (Drosophila melanogaster)


name: SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Homo sapiens)


name: (S)-5'-oxoaverantin + H(+) + NADH => (1'S,5'S)-5'-hydroxyaverantin + NAD(+)


name: eicosanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4-hydroxy-6-(2-oxohenicosyl)pyran-2-one + 3 CO2 + 4 CoA


name: cyanurate + isopropylamine => H(+) + H2O + N-isopropylammelide


name: ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Mus musculus)


name: ESTG binds ESR2:chaperone complex (Xenopus tropicalis)


name: acetophenone + H(+) + NADPH => (R)-1-phenylethanol + NADP(+)


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Caenorhabditis elegans)


name: MAF1 translocates to the nucleus (Schizosaccharomyces pombe)


name: SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)


name: L-seryl-[protein] + phosphate => H2O + O-phospho-L-seryl-[protein]


name: HIF-alpha translocates from cytosol to nucleus (Gallus gallus)


name: 5D-5-O-methyl-chiro-inositol + NADP(+) => 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH


name: ANOs transport cytosolic Cl- to extracellular region (Sus scrofa)


name: PGLYRP1 binds bacterial peptidoglycan (Bos taurus)


name: SIRT1 deacetylates TAF1B in SL1 complex (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA


name: cyclo(L-phenylalanyl-L-leucyl) + 2 O2 <=> albonoursin + 2 H2O2


name: NFE2L2 binds the TKT gene (Homo sapiens)


name: Interaction of Csk with PAG (Homo sapiens)


name: 1-O-(1Z)-hexadecenyl-2 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+)


name: 27-hydroxysterol binds ESR1, ESR2 (Bos taurus)


name: 2 H(+) + NADH + pyruvate => H2O + methylglyoxal + NAD(+)


name: mRNA base-pairing translational repressor activity


name: a cytidine in tRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate <=> CO2 + deoxyviolacein + 2 H2O + NADP(+)


name: Interleukin-27 dissociates from Interleukin-27 receptor (Canis familiaris)


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Canis familiaris)


name: BRCA1 forms a heterodimer with BARD1 (Bos taurus)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Xenopus tropicalis)


name: ERBB4s80:STAT5A complex translocates to the nucleus (Sus scrofa)


name: Collagen type III degradation by MMP1,8,9,13 (Canis familiaris)


name: 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein] => 1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein]


name: FGFR3b binds to FGF (Caenorhabditis elegans)


name: Caspase-mediated cleavage of gelsolin (Mus musculus)


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine = (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Homo sapiens)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Schizosaccharomyces pombe)


name: L-alanine + L-aspartate 4-semialdehyde => L-2,4-diaminobutanoate + pyruvate


name: Activated FGFR2:pFRS binds GRB2:SOS1 (Mus musculus)


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Canis familiaris)


name: (10bS,4aR)-noroxomaritidine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 4'-O-methylnorbelladine + O2 + reduced [NADPH--hemoprotein reductase]


name: p14ARF mutants do not bind C1QBP (Homo sapiens)


name: Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind GRB2:GAB1 (Homo sapiens)


name: PLG(20-810) binds aprotinin (Homo sapiens)


name: dodecanoyl-CoA + H2O = CoA + dodecanoate + H(+)


name: 4-aminobutanoate + L-arginine => H2O + N(2)-(4-aminobutanoyl)-L-arginine


name: (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + NAD(+) => (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H(+) + NADH


name: Fibrillin-1 binds latent TGF-beta (Homo sapiens)


name: 5,10-methylenetetrahydromethanopterin + 2 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) => 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Dissociation of the Gi alpha:G olf complex (Sus scrofa)


name: RAC3 binds effectors at the plasma membrane (Dictyostelium discoideum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 H2O = 2 (9Z)-octadecenoate + 2 H(+) + sn-glycero-3-phosphoethanolamine


name: chorismate <=> 3-hydroxybenzoate + pyruvate


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Danio rerio)


name: CBL monoubiquitinates activated MET (Gallus gallus)


name: Activation of TRESK (Saccharomyces cerevisiae)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] => 2-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = an anthocyanidin 3,5-di-O-beta-D-glucoside + 2 H(+) + UDP


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Bos taurus)


name: MT3 exchanges zinc for copper (Danio rerio)


name: 4-O-deacetylvindoline + acetyl-CoA <=> CoA + vindoline


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphate + H(+) + NADPH <=> 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphate + NADP(+)


name: glyoxylate(in) + sulfate(out) = glyoxylate(out) + sulfate(in)


name: Autophosphorylation of SRC (Caenorhabditis elegans)


name: acetyl-CoA + 10 AH2 + 2 H(+) + 7 malonyl-CoA + 5 S-adenosyl-L-methionine <=> 10 A + 7 CO2 + 8 CoA + dehydroprobetaenone I + 6 H2O + 5 S-adenosyl-L-homocysteine


name: high-affinity secondary active nitrite transmembrane transporter activity


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Xenopus tropicalis)


name: (2-aminobenzyl)malonyl-CoA + H(+) + O2 <=> (E)-2-aminocinnamoyl-CoA + CO2 + H2O2


name: RHOA GEFs activate RHOA (Drosophila melanogaster)


name: AH2 + androst-4-ene-3,17-dione + O2 <=> A + H2O + testololactone


name: GUK1 phosphorylates 6TGMP to 6TGDP (Schizosaccharomyces pombe)


name: ATM phosphorylates PIDD1 (Rattus norvegicus)


name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria (Caenorhabditis elegans)


name: Oxytocin receptor bind oxytocin (Bos taurus)


name: USP13 binds SIAH2 (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+) => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O


name: GLYCTK phosphorylates DGA to 3PDGA (Caenorhabditis elegans)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Plasmodium falciparum)


name: (E)-cinnamaldehyde + H(+) + NADPH => (E)-cinnamyl alcohol + NADP(+)


name: TRAF3/or TRAF6 interacts with IPS-1 (Gallus gallus)


name: Nascent CMs transform into mature CMs (Mus musculus)


name: estrone + H(+) + sulfate => estrone 3-sulfate + H2O


name: Endostatin degradation by cathepsins (Canis familiaris)


name: acetylsalicylate + L-lysyl-[protein] => H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate


name: chloride(out) + D-methionine(out) + 2 Na(+)(out) <=> chloride(in) + D-methionine(in) + 2 Na(+)(in)


name: PI3K inhibitors block PI3K catalytic activity (Homo sapiens)


name: DNA polymerase alpha:primase binds at the origin (Drosophila melanogaster)


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Bos taurus)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Schizosaccharomyces pombe)


name: Phosphorylation of L1 by EPHB2 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxyhexacosanoyl)-sphinganine => a 1,2-diacyl-sn-glycerol + Ins-1-P-Cer(d18:0/2-OH-26:0)


name: Nephrin dimer:KIRREL binds FYN (Bos taurus)


name: ASPA deacetylates NAA to acetate and L-aspartate (Mus musculus)


name: ADP + phosphate + propanoyl-CoA => ATP + CoA + propanoate


name: 6-O-alpha-D-glucopyranosyl-D-fructose + H2O => alpha-D-glucose + D-fructose


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Schizosaccharomyces pombe)


name: adenosine(2142) in 25S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(2142) in 25S rRNA + S-adenosyl-L-homocysteine


name: p-S54-PDE4B hydrolyses cAMP (Bos taurus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP


name: H(+) + NADPH + O2 + verruculide A = chrodrimanin E + H2O + NADP(+)


name: ATP(in) + CoA(in) + H(+)(out) + tetracosanoate(out) <=> AMP(in) + diphosphate(in) + H(+)(in) + tetracosanoyl-CoA(in)


name: Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Bos taurus)


name: 3,5-dichlorocatechol + O2 = (2E,4E)-2,4-dichloromuconate + 2 H(+)


name: USP1:WDR48 binds monoUb:K164-PCNA (Schizosaccharomyces pombe)


name: (6E)-8-oxogeranial + H(+) + NADPH => (R)-8-oxocitronellyl enol + NADP(+)


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Sus scrofa)


name: NFE2L2 binds CREBBP,EP300 (Caenorhabditis elegans)


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Danio rerio)


name: Transfer of NEDD8 to AcM-UBE2F (Plasmodium falciparum)


name: NT5C3B hydrolyses 7MGP to 7MG (Bos taurus)


name: a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA


name: (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate + H2O => (R)-glycerate + alpha-D-mannose 6-phosphate


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Caenorhabditis elegans)


name: neurotransmitter receptor regulator activity


name: Lsm1-7 Complex binds deadenylated mRNA (Xenopus tropicalis)


name: Joining of adjacent Okazaki fragments of the C-strand (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate = diphosphate + sibirene


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Mus musculus)


name: (2Z,6E)-farnesyl diphosphate => (E)-beta-farnesene + diphosphate


name: I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)


name: Retromer associates with WLS (Gallus gallus)


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Rattus norvegicus)


name: N-(9Z-octadecenoyl)-(2S)-hydroxyglycine => (9Z)-octadecenamide + glyoxylate


name: an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe) => an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe)


name: high-affinity copper ion transmembrane transporter activity


name: Journey of cargo through Golgi complex (Danio rerio)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Sus scrofa)


name: FGFRL1 binds SPRED1/2 (Drosophila melanogaster)


name: H(+) + L-rhamnono-1,4-lactone + NADPH => L-rhamnofuranose + NADP(+)


name: SEPHS2 phosphorylates H2Se to form SELP (Danio rerio)


name: 23,24-dihydrocucurbitacin B + NADP(+) <=> cucurbitacin B + H(+) + NADPH


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Mus musculus)


name: 2-oxoglutarate + L-arginyl-[ribosomal protein uL16] + O2 => (3R)-3-hydroxy-L-arginyl-[ribosomal protein uL16] + CO2 + succinate


name: ABCC3 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)


name: ZCRB1 binds 5'UTR of SARS-CoV-1 genomic RNA (Homo sapiens)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Rattus norvegicus)


name: TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome (Homo sapiens)


name: CRHR1,CRHR2-1 binds CRH,UCN (Rattus norvegicus)


name: Activation of MT-MMPs by FURIN (Gallus gallus)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Gallus gallus)


name: EP4 subtype prostaglandin E2 receptor binding


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Mus musculus)


name: dodecanoyl-CoA + L-seryl-[protein] <=> CoA + O-dodecanoyl-L-seryl-[protein]


name: Neurofascin binds Ankyrin-G (Homo sapiens)


name: Group 3 - Selective Cl- transport (Caenorhabditis elegans)


name: 8,20-dihydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 8-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: hydrogencarbonate(out) + selenite(out) + Zn(2+)(out) => hydrogencarbonate(in) + selenite(in) + Zn(2+)(in)


name: glycine(in) + H(+)(in) = glycine(out) + H(+)(out)


name: PREDN,PREDL diffuse into hepatic cells (Homo sapiens)


name: Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching (Homo sapiens)


name: Anthrax lef cleaves target cell MAP2K7 (MEK7) (Homo sapiens)


name: Phosphorylated TAK1 leaves activated TLR receptor complex (Canis familiaris)


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Mus musculus)


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Rattus norvegicus)


name: H2O + N-acetyl-beta-alanine = acetate + beta-alanine


name: SLC7A8-mediated uptake of neutral amino acids (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: Recruitment of GADS:SLP-76 to p-5Y-LAT (Mus musculus)


name: GTP + H2O => 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)


name: 4-hydroxybenzoate + bromide + 2 H(+) + NADPH + O2 = 3-bromo-4-hydroxybenzoate + 2 H2O + NADP(+)


name: hexadecyltrimethylammonium chloride monooxygenase activity


name: JAK1-mediated phosphorylation of RAF1 (Gallus gallus)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Mus musculus)


name: ATP + beta-alanine + L-lysine = ADP + beta-alanyl-L-lysine + H(+) + phosphate


name: Export of peptide loaded MHC class I complex to PM (Rattus norvegicus)


name: 3-hydroxy-L-kynurenine + H2O => 3-hydroxyanthranilate + H(+) + L-alanine


name: ADP-alpha-D-ribose 1''-phosphate + H2O <=> ADP-D-ribose + phosphate


name: Formation of HIF:CBP:p300 complex at promoters (Caenorhabditis elegans)


name: ATP + H2O + L-methionine <=> diphosphate + phosphate + S-adenosyl-L-methionine


name: 2xPDXK:2xZn2+ phosphorylates PXA (Sus scrofa)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane (Mus musculus)


name: 3-methylbutan-2-one + H(+) + NADPH + NH4(+) => 3-methyl-2-aminobutane + H2O + NADP(+)


name: rhamnetin + S-adenosyl-L-methionine = 7,4'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine


name: 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: NADP(+) + prostaglandin F2alpha => H(+) + NADPH + prostaglandin H2


name: G protein-coupled GABA receptor activity


name: RCC1 stimulates GDP to GTP exchange on RAN (Xenopus tropicalis)


name: CDK5 phosphorylates DARPP-32 on Thr75 (Gallus gallus)


name: N-tetradecanoyl-(2S)-hydroxyglycine => glyoxylate + tetradecamide


name: IL4:IL4R:JAK2 binds IL2RG:JAK3 (Mus musculus)


name: D-arabino-hex-3-ulose 6-phosphate <=> beta-D-fructose 6-phosphate


name: CEBPB gene transcription is enhanced by phospho-CREB1 and phospho-STAT3 (Homo sapiens)


name: Phosphorylation of MEF2 proteins by p38 (Dictyostelium discoideum)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Sus scrofa)


name: 7,9,9'-tri-cis-neurosporene + a quinone => 7,7',9,9'-tetra-cis-lycopene + a quinol


name: 2-hydroxyhexadecanoate + ATP + CoA <=> 2-hydroxyhexadecanoyl-CoA + AMP + diphosphate


name: ATXN3 binds polyUb-PARK2 (Plasmodium falciparum)


name: 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 32-oxo-24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: PP2A methylation by LCMT1 (Dictyostelium discoideum)


name: 5,6-dihydrouridine(20) in tRNA + NADP(+) => H(+) + NADPH + uridine(20) in tRNA


name: 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate => 9-(10Z-heptadecenoyloxy)-octadecanoate + di-(10Z)-heptadecenoylglycerol


name: H2O + N,N-dimethylglycine + oxidized 2[4Fe-4S]-[ferredoxin] => formaldehyde + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin] + sarcosine


name: oxalate + succinyl-CoA = oxalyl-CoA + succinate


name: (E)-4-coumaroyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] <=> CoA + H(+) + myricetin 3-O-[(6-O-(E)-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Sus scrofa)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Homo sapiens)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Drosophila melanogaster)


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Drosophila melanogaster)


name: Active NIK phosphorylates IKKA dimer (Rattus norvegicus)


name: (S)-2,3-diaminopropanoate + 2-oxoglutarate + H(+) + NADH => H2O + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD(+)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: (2E,6E,10E,14E)-geranylfarnesol + H2O = preluffariellolide A


name: Coumarin is 7-hydroxylated by CYP2A6 (Homo sapiens)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O <=> 1,2-diacyl-sn-glycero-3-phosphoethanolamine-N-glycine + [protein]-C-terminal <stereo>L-</stereo>amino acid


name: (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione => (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Mus musculus)


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: H2O + N-acetyl-beta-D-6-sulfogalactosaminyl-(1->4)-alpha-L-iduronyl-(1->3)-N-acetyl-D-6-sulfogalactosamine <=> alpha-L-iduronyl-(1->3)-N-acetyl-D-6-sulfogalactosamine + N-acetyl-D-6-sulfogalactosamine


name: 2xPPCS ligates PPanK with Cys (Schizosaccharomyces pombe)


name: 5-aminolevulinate + CO2 + CoA => glycine + H(+) + succinyl-CoA


name: [(1->4)-alpha-D-glucosyl](n) + alpha-maltose 1-phosphate <=> [(1->4)-alpha-D-glucosyl](n+2) + phosphate


name: DUOX1,2 reduce O2 to H2O2 (Rattus norvegicus)


name: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate


name: hyodeoxycholate + UDP-alpha-D-glucuronate <=> H(+) + hyodeoxycholate 6-O-(beta-D-glucuronate) + UDP


name: Translocation of Cdc25 to the nucleus (Mus musculus)


name: 12,18-didecarboxysiroheme + 2 AH2 + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 A + 2 acetate + Fe-coproporphyrin III + 2 H(+) + 2 L-methionine


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Canis familiaris)


name: 5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)


name: GPI dimer isomerizes Fru(6)P to G6P (Schizosaccharomyces pombe)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Bos taurus)


name: 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H2O = (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-3-hexadecanoyl-sn-glycerol + H(+)


name: L-threonyl-[protein] + N-acetyl-D-glucosamine => 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H2O


name: CO binds to Cytochrome c oxidase (Homo sapiens)


name: Release of platelet cytosolic components (Homo sapiens)


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Sus scrofa)


name: L1 trans-homophilic interaction (Homo sapiens)


name: SHC1-2 bound to MET recruits GRB2:SOS1 (Mus musculus)


name: delta-guaiene + diphosphate => (2E,6E)-farnesyl diphosphate


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Rattus norvegicus)


name: H(+) + NADH + NH4(+) + S-(acetaldehyde)-L-cysteine => H2O + NAD(+) + S-(2-aminoethyl)-L-cysteine


name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Xenopus tropicalis)


name: 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O


name: thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Danio rerio)


name: Activation of SHP2 through the binding to phospho-Gab1 (Xenopus tropicalis)


name: CSF3 dimer:CSFR:LYN:JAK1 binds CSFR:LYN:JAK1 (Homo sapiens)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Homo sapiens)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Canis familiaris)


name: Dissociation of phospho-Cdh1 from the APC/C complex (Homo sapiens)


name: SLC46A1 transports hemes from extracellular region to cytosol (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: 1,4-dihydroxy-2-naphthoyl-CoA + H2O <=> 1,4-dihydroxy-2-naphthoate + CoA + H(+)


name: butanoate(out) + estrone 3-sulfate(in) <=> butanoate(in) + estrone 3-sulfate(out)


name: 3-hydroxypyruvate + H2O2 + NH4(+) => D-serine + H2O + O2


name: JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Mus musculus)


name: K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Homo sapiens)


name: 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH => anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+)


name: MME:Zn2+ hydrolyses AGT(34-43) (Xenopus tropicalis)


name: D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+) => diphosphate + GDP-D-glycero-alpha-D-manno-heptose


name: [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine => [calmodulin]-L-lysine + S-adenosyl-L-methionine


name: alpha,beta-didehydrotryptophan + H2O2 => L-tryptophan + O2


name: PA is dephosphorylated to DAG by LPIN (Homo sapiens)


name: GTP-bound RAC contributes to JNK activation (Bos taurus)


name: nucleobase-containing compound kinase activity


name: H(+) + NADH + uracil => 5,6-dihydrouracil + NAD(+)


name: Phosphorylation of LAT by p-SYK (Homo sapiens)


name: 3 CO2 + gibberellin A9 + 2 H2O + 2 succinate => 2 2-oxoglutarate + gibberellin A12 + H(+) + 3 O2


name: 2 a 1-acylglycerol <=> a 1,2-diacylglycerol + glycerol


name: 2-hydroxyspirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2,2-dihydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PDGFRs bind type II TKI (Xenopus tropicalis)


name: SMURF1/2 dissociates from ub-PTCH1 (Canis familiaris)


name: H2O + octanoylglycerol => glycerol + H(+) + octanoate


name: GGCT transforms gGluCys to OPRO (Danio rerio)


name: glycerol + NADP(+) = D-glyceraldehyde + H(+) + NADPH


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Canis familiaris)


name: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein]


name: NAALADases hydrolyse NAAG (Rattus norvegicus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine => 1-O-(1Z-alkenyl)-2-acetyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine


name: guanine + queuosine(34) in tRNA => guanosine(34) in tRNA + queuine


name: protein-DNA covalent cross-linking activity


name: succinate(out) + urate(in) => succinate(in) + urate(out)


name: Ubiquitinated TP53 translocates to the cytosol (Mus musculus)


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Mus musculus)


name: Ficolin-3 binds to molecular patterns on the target cell surface  (Homo sapiens)


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Mus musculus)


name: p-S407,Y641-STAT6 is dimerized (Drosophila melanogaster)


name: ANO1 inhibitors bind ANO1 (Rattus norvegicus)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O => (9Z)-octadecenoate + a 2-acyl-sn-glycero-3-phosphocholine + H(+)


name: REG3A binds bacterial phospholipids (Caenorhabditis elegans)


name: (2R)-3-sulfolactate + NAD(+) => 3-sulfopyruvate + H(+) + NADH


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Canis familiaris)


name: 3-aminobutanoate + pyruvate = acetoacetate + L-alanine


name: SUMOylation of NR1H4 with SUMO1 (Bos taurus)


name: 19-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2


name: ATP + H(+) + IC-asc-C7 <=> diphosphate + IC-asc-C7-AMP


name: Factor D cleaves C3(H2O)-bound Factor B (Homo sapiens)


name: 2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Canis familiaris)


name: beta-D-fructose 6-phosphate + UDP-alpha-D-glucose <=> H(+) + sucrose 6(F)-phosphate + UDP


name: DKC1 binds SHQ1 (Drosophila melanogaster)


name: The p75NTR C-terminal fragment enters endosomes (Xenopus tropicalis)


name: CYP2E1 monooxygenates APAP to NAPQI (Bos taurus)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Mus musculus)


name: 4 H(+) + 4 malonyl-CoA = (3,5-dihydroxyphenyl)acetyl-CoA + 4 CO2 + 3 CoA + H2O


name: CDC42 GAPs stimulate CDC42 GTPase activity (Dictyostelium discoideum)


name: adenosine 3',5'-bisphosphate(out) + FAD(in) = adenosine 3',5'-bisphosphate(in) + FAD(out)


name: H(+) + momilactone A + NADH => 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide + NAD(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: C-ter TLR7 dimer binds HCQ (Canis familiaris)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Dictyostelium discoideum)


name: Formation of ORC(1-5) complex (Homo sapiens)


name: Interaction of Tie2 with Ang1 (Canis familiaris)


name: PGRMC2:Hemes translocate to the nucleus (Homo sapiens)


name: 4-hydroxybutanoyl-CoA + ADP + phosphate => 4-hydroxybutanoate + ATP + CoA


name: D-glyceraldehyde 3-phosphate + H2O + NADP(+) => (2R)-3-phosphoglycerate + 2 H(+) + NADPH


name: NADP(+) + propanal <=> acrolein + H(+) + NADPH


name: PEA15 binds MAPK monomers and dimers (Homo sapiens)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Gallus gallus)


name: a 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA + ADP + H(+) => an alpha-Kdo-(2->6)-lipid IVA + ATP