name: L-isoleucine(in) + L-phenylalanine(out) = L-isoleucine(out) + L-phenylalanine(in)


name: a D-alpha-amino acid + a tRNA + H(+) => a D-aminoacyl-tRNA + H2O


name: 4-hydroxyestrone + UDP-alpha-D-glucuronate = 4-hydroxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Danio rerio)


name: PROT mediates L-proline uptake (Rattus norvegicus)


name: holo-FDPS dimer binds NBPs (Rattus norvegicus)


name: 5-oxopentanoate + H2O + NADP(+) = glutarate + 2 H(+) + NADPH


name: alpha-maltotriose + beta-maltose <=> alpha-maltotetraose + beta-D-glucose


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Bos taurus)


name: D-cellotriono-1,5-lactone + H2O2 => D-cellotriose + O2


name: Addition of nucleotides leads to transcript elongation (Bos taurus)


name: O2 + octadecanoate + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Bos taurus)


name: (+)-kolavenyl diphosphate + H2O => (+)-kolavelool + diphosphate


name: 3 H(+) + 3 malonyl-CoA => 1,3,5-trihydroxybenzene + 3 CO2 + 3 CoA


name: histone H3R17 arginine deiminase activity


name: ADP + ADP <=> AMP + ATP [AK2] (Schizosaccharomyces pombe)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 => (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Sus scrofa)


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Xenopus tropicalis)


name: canalicular bile acid transmembrane transporter activity


name: ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate <=> ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate


name: Ca2+ influx through voltage gated Ca2+ channels (Drosophila melanogaster)


name: 2 Na(+)(out) + taurolithocholate 3-sulfate(out) <=> 2 Na(+)(in) + taurolithocholate 3-sulfate(in)


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Saccharomyces cerevisiae)


name: tamatinib-resistant FLT3 mutants don't bind tamatinib (Homo sapiens)


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Sus scrofa)


name: Expression of Macrophage migration inhibitory factor (Homo sapiens)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)


name: STEAP3-like proteins reduce Fe3+ to Fe2+ (Sus scrofa)


name: Activated FGFR4 binds FRS3 (Xenopus tropicalis)


name: 3-oxopropanoyl-CoA + H2O = 3-oxopropanoate + CoA + H(+)


name: formate + succinyl-CoA => formyl-CoA + succinate


name: H(+) + NADH + O2 + toluene = 2-hydroxytoluene + H2O + NAD(+)


name: 3'-phosphoadenylyl sulfate + an aliphatic (Z)-desulfo-glucosinolate <=> a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + adenosine 3',5'-bisphosphate + H(+)


name: GUCA binds Ca2+ to form GUCA:Ca2+ (Dictyostelium discoideum)


name: D-maltotetraose + H2O = alpha-D-glucose + D-maltotriose


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Homo sapiens)


name: factor VIIIa associates with cell membrane (Bos taurus)


name: IkB is ubiquitinated and degraded (Bos taurus)


name: L-tyrosyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O-(N-acetyl-alpha-D-glucosaminyl)-L-tyrosyl-[protein] + UDP


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Bos taurus)


name: C37-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+) => 2 (S)-methylmalonyl-CoA + 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH


name: (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 = (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Sus scrofa)


name: D-cellohexaono-1,5-lactone + H2O <=> D-cellohexaonate + H(+)


name: RNLS:FAD oxidises dh-beta-NAD to NAD+ (Homo sapiens)


name: a 1,2-diacylglycerol + a monoacyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol


name: SodB reduces superoxide to H2O2 (Homo sapiens)


name: 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP => 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine


name: N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine = H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: ubiquitination-like modification-dependent protein binding


name: HLA-A specific activating MHC class I receptor activity


name: a ganglioside GM2 + H2O = a ganglioside GM3 + N-acetyl-beta-D-galactosamine


name: Binding of ADAR1 homodimer to dsRNA duplex (Rattus norvegicus)


name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) (Canis familiaris)


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Xenopus tropicalis)


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Rev molecules assemble onto the RRE RNA sequence through their ARM sequence (Homo sapiens)


name: MRN bound to shortened telomeres activates ATM (Saccharomyces cerevisiae)


name: Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane (Rattus norvegicus)


name: TFAP2B homodimer binds YEATS4 (Caenorhabditis elegans)


name: Na(+)(out) + uridine(out) <=> Na(+)(in) + uridine(in)


name: ATP + CoA + isophthalate = AMP + diphosphate + isophthalyl-CoA


name: AH2 + cremeomycin = 2-hydroxy-4-methoxybenzoate + A + N2


name: RHOQ GAPs stimulate RHOQ GTPase activity (Gallus gallus)


name: Receptor CCR10 binds CCL27 and 28 ligands (Danio rerio)


name: Formation of classic pathway C5 convertase (Bos taurus)


name: H(+)(out) + L-histidine(out) <=> H(+)(in) + L-histidine(in)


name: prostaglandin E1 => H2O + prostaglandin A1


name: Oxidative damage to the AP site (Dictyostelium discoideum)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + ATP = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+)


name: (R)-pantolactone + A = 2-dehydropantolactone + AH2


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Danio rerio)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Bos taurus)


name: dipicolinate + H(+) + NADH => (S)-2,3-dihydrodipicolinate + NAD(+)


name: 3-hydroxy-4-methylanthranilate + ATP + H(+) <=> 3-hydroxy-4-methylanthranilyl-5'-AMP + diphosphate


name: MAPK6 is degraded by the 26S proteasome (Bos taurus)


name: a 1-acylglycerone 3-phosphate + CoA => an acyl-CoA + dihydroxyacetone phosphate


name: a dolichyl beta-D-glucosyl phosphate + chenodeoxycholate = a dolichyl phosphate + beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H(+)


name: 1-cyclohexylethanamine + H2O + NADP(+) = 1-cyclohexylethanone + H(+) + NADPH + NH4(+)


name: Interaction of Tie2 and Dok-2 (Gallus gallus)


name: carnosine(out) + H(+)(out) = carnosine(in) + H(+)(in)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Saccharomyces cerevisiae)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Rattus norvegicus)


name: PTK6 phosphorylates KHDRBS3 (Bos taurus)


name: 19-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase]


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Canis familiaris)


name: RAC1:GTP binds NOX3 complex (Sus scrofa)


name: an adenosine in mRNA + S-adenosyl-L-methionine <=> an N(1)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: Mitochondrial BTD hydrolyses BCTN (Rattus norvegicus)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + phosphate => 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O


name: p-Y701-STAT1 dimerizes (Canis familiaris)


name: AKT inhibitors block AKT membrane recruitment (Homo sapiens)


name: B-WICH complex binds rDNA promoter (Homo sapiens)


name: a (2R,3R)-flavan-3-ol + 2 NAD(+) = an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADH


name: Cleavage of uracil by MBD4 glycosylase (Bos taurus)


name: Formation of the Flap Intermediate (Caenorhabditis elegans)


name: PTGS2 dimer binds PTGS2 inhibitors (Sus scrofa)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)


name: ADP + H(+) + N-acetyl-D-glucosamine 6-phosphate => ATP + N-acetyl-D-glucosamine


name: (2R)-hydroxyhexadecanoyl-CoA = formyl-CoA + pentadecanal


name: Active G alpha (z) binds RGS proteins (Homo sapiens)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Sus scrofa)


name: Mitochondrial FPGS-1 transforms THF to THFPG (Sus scrofa)


name: Loss-of-function NF1 variants don't stimulate RAS GTPase activity (Homo sapiens)


name: [thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite = 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol


name: WNT ligands traffic to the Golgi (Caenorhabditis elegans)


name: ATPase-coupled hydroxyectoine transmembrane transporter activity


name: Cinaciguat binds sGC:NO (Rattus norvegicus)


name: ADA deamidates RBV (Dictyostelium discoideum)


name: 11-oxo-5Z,9,12E,14E-prostatetraenoate + H2O => 15-deoxy-Delta(12,14)-prostaglandin J2 + glycerol + H(+)


name: CO2 + CoA + olivetol => 3,5,7-trioxododecanoyl-CoA


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Mus musculus)


name: ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA (Mus musculus)


name: long-chain fatty acid transporter activity


name: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity


name: cyclic nucleotide phosphodiesterase activator activity


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)


name: S-adenosyl-L-methionine + scopoletin = H(+) + S-adenosyl-L-homocysteine + scoparone


name: propanoyl-CoA + succinate = propanoate + succinyl-CoA


name: H2O + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine = H(+) + N-hexadecanoylethanolamine + sn-glycerol 3-phosphate


name: GRKs bind ADRB2:Catecholamine (Rattus norvegicus)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Bos taurus)


name: ALDHs oxidise atRAL to atRA (Homo sapiens)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)


name: L-arginine(out) + L-histidine(in) => L-arginine(in) + L-histidine(out)


name: RHOT2 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: ALOX5 oxidises EPA to 5-HEPE (Xenopus tropicalis)


name: a fatty acid ethyl ester + H2O => a fatty acid + ethanol + H(+)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Xenopus tropicalis)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)


name: Beta-catenin translocates to the nucleus (Sus scrofa)


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Rattus norvegicus)


name: ITP + N-acetyl-D-glucosamine = H(+) + IDP + N-acetyl-D-glucosamine 6-phosphate


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: Furin cleaves pro-factor X to factor X (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: Dimerization of DAP12 (Canis familiaris)


name: 2-oxoglutarate + kanamycin B + O2 => 2'-dehydrokanamycin A + CO2 + NH4(+) + succinate


name: 15,9'-di-cis-phytofluene + a plastoquinone <=> 9,9',15-tri-cis-zeta-carotene + a plastoquinol


name: Formation of RAD50:MRE11 complex (Plasmodium falciparum)


name: hyocholate + UDP-alpha-D-glucuronate <=> hyocholoyl-24-O-(beta-D-glucuronate) + UDP


name: (2E,6E)-farnesyl diphosphate = diphosphate + selina-4(15),7(11)-diene


name: CYP26C1 4-hydroxylates 9cRA (Gallus gallus)


name: Formation of the NSL complex (Homo sapiens)


name: 2,3-dihydroxydiphenyl ether dioxygenase activity


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: CaMKK autophosphorylates in the nucleus (Rattus norvegicus)


name: (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H2O = 6-methyl-3,7-dioxodecanedioyl-CoA


name: candesartan + UDP-alpha-D-glucuronate => candesartan O-beta-D-glucuronoside + UDP


name: (2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + 6 diphosphate


name: (2E)-geranyl diphosphate => diphosphate + sabinene


name: SUMOylation of XPC with SUMO1 (Plasmodium falciparum)


name: CysS248-MPST:TXN2 dissociates (Homo sapiens)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Bos taurus)


name: (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> (R)-mandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Translocation of CaN:CaM:NFAT to nucleus (Rattus norvegicus)


name: 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2 => 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+)


name: H2O + N-(9Z-hexadecenoyl) ethanolamine => (9Z)-hexadecenoate + ethanolamine


name: nitrate(out) + ubiquinol-8(in) <=> H2O(out) + nitrite(out) + ubiquinone-8(in)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 <=> A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O


name: GNLY binds the bacterial cell surface (Bos taurus)


name: chloride(in) + L-lysine(in) + 2 Na(+)(in) => chloride(out) + L-lysine(out) + 2 Na(+)(out)


name: TFIIH-class transcription factor complex binding


name: Excess homocysteine yields homolanthionine and H2S (Rattus norvegicus)


name: Activation of RAC1 by VAV2/3 (Sus scrofa)


name: (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + H(+) => (8Z,11Z,14Z)-heptadecatrienal + CO2 + H2O


name: 5-PP-IP4 transports from the nucleus to the cytosol (Homo sapiens)


name: Regeneration of eEF1A:GTP by eEF1B activity (Rattus norvegicus)


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Rattus norvegicus)


name: a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+)


name: 3-iodo-L-tyrosine + iodide + NADP(+) = 3,5-diiodo-L-tyrosine + H(+) + NADPH


name: GRK2 sequesters activated Gq (Rattus norvegicus)


name: (6S)-5,6,7,8-tetrahydrofolate + 5-methyl-UMP + NADP(+) => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + UMP


name: Degradation of ubiquitinated SMAD3 (Mus musculus)


name: DOCKs bind to RhoGEFs (Rattus norvegicus)


name: The acetyl group from acetyl-CoA is transferred to the NAT2 (Mus musculus)


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Xenopus tropicalis)


name: NT5C3B hydrolyses 7MGP to 7MG (Mus musculus)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Drosophila melanogaster)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Mus musculus)


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Xenopus tropicalis)


name: 2 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone = 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate


name: 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H2O <=> H(+) + hexadecanoate + sn-glycero-3-phospho-L-serine


name: (+)-valencene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (+)-nootkatone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Drosophila melanogaster)


name: (4-hydroxyphenyl)acetaldehyde + methylamine => (R)-synephrine


name: D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate => 2 D-sedoheptulose 7-phosphate


name: GSTZ1 dimer dehalogenates DCA to glyoxylate (Dictyostelium discoideum)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Bos taurus)


name: 4-hydroxy-6-nonadecylpyran-2-one + 2 CO2 + 3 CoA => eicosanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: WLS:WNT complex is internalized for maturation into exosomes (Sus scrofa)


name: EPO:p-EPOR:p-JAK2:LYN:IRS2 binds CRKL:RAPGEF1 (Homo sapiens)


name: PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release (Canis familiaris)


name: [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + 3 H(+) + 3 UDP => N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + 3 UDP-N-acetyl-alpha-D-galactosamine


name: indole + NH4(+) + pyruvate => H2O + L-tryptophan


name: GAPDH tetramers reduce 1,3BPG to GA3P (Plasmodium falciparum)


name: 2 chloride(in) + K(+)(in) + Na(+)(in) => 2 chloride(out) + K(+)(out) + Na(+)(out)


name: sphinganine + UDP-alpha-D-galactose => beta-D-galactosyl-(1<->1')-sphinganine + H(+) + UDP


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Bos taurus)


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Canis familiaris)


name: Co(I)-[methanol-specific corrinoid protein] + H(+) + methanol = H2O + methyl-Co(III)-[methanol-specific corrinoid protein]


name: 9S,10-epoxy-(10,12Z)-octadecadienoate + H(+) + L-aspartyl-[protein] <=> 9-O-10-oxo-(12Z)-octadecenoate L-aspartatyl ester-[protein]


name: 2-oxoglutarate + a 3-methyl fatty acyl-CoA + O2 = a 2-hydroxy-3-methyl fatty acyl-CoA + CO2 + succinate


name: RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Caenorhabditis elegans)


name: H(+)(out) + L-histidine(out) + L-ornithine(in) => H(+)(in) + L-histidine(in) + L-ornithine(out)


name: 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + NAD(+) => 3-acetyl-3-devinylchlorophyllide a + H(+) + NADH


name: RUNX2 and SMAD1 complex binds the SMAD6 gene promoter (Homo sapiens)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Dictyostelium discoideum)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Caenorhabditis elegans)


name: OCT3 mediates renal uptake of organic cations (Caenorhabditis elegans)


name: 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate


name: L-glutamate + L-glutamyl-[protein] => gamma-L-glutamyl-L-glutamyl-[protein] + H2O


name: NID1 degradation by MMP19 (Mus musculus)


name: c-src associates with Cx43 in gap junctions (Canis familiaris)


name: Tropoelastin associates with microfibrils (Mus musculus)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Bos taurus)


name: Expression of GATA6 in definitive endoderm (Homo sapiens)


name: Two DITs combine to form thyroxine (Caenorhabditis elegans)


name: (9Z)-octadecenamide + glyoxylate => N-(9Z-octadecenoyl)-(2S)-hydroxyglycine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-dodecanoyl-sn-glycero-3-phosphocholine <=> 1-dodecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: H(+) + NADH + O2 + toluene <=> 2-hydroxytoluene + H2O + NAD(+)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + diphosphate = 5-amino-4-imidazolecarboxyamide + 5-phospho-alpha-D-ribose 1-diphosphate


name: SYVN1 ubiquitinates Hh C-terminal fragments (Homo sapiens)


name: beta-dihydromenaquinone-9 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + omega-hydroxy-beta-dihydromenaquinone-9 + 2 oxidized [2Fe-2S]-[ferredoxin]


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Canis familiaris)


name: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Canis familiaris)


name: 2-demethylmenaquinol-10 + S-adenosyl-L-methionine => H(+) + menaquinol-10 + S-adenosyl-L-homocysteine


name: (S)-norcodamine + H(+) + S-adenosyl-L-homocysteine => (S)-norreticuline + S-adenosyl-L-methionine


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Xenopus tropicalis)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Xenopus tropicalis)


name: H(+) + L-kynurenine + NADPH + O2 <=> 3-hydroxy-L-kynurenine + H2O + NADP(+)


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)


name: Loading of claspin onto DNA during replication origin firing (Bos taurus)


name: anisole + O2 + reduced [NADH--hemoprotein reductase] = formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase] + phenol


name: EPH:EFN tetramers oligomerise (Danio rerio)


name: (9Z,12Z)-hexadecadienoyl-CoA + AH2 + O2 = (9Z,12Z,15Z)-hexadecatrienoyl-CoA + A + 2 H2O


name: glycine + glycolaldehyde => 4-hydroxy-L-threonine


name: (E)-2-((N-methylformamido) methylene)succinate + H(+) + 2 H2O <=> CO2 + formate + methylamine + succinate semialdehyde


name: CRHR2-2 binds CRH,UCN,UCN2,UCN3 (Homo sapiens)


name: 7 CO2 + 7 CoA + 2 H2O + 5 NADP(+) + narbonolide => 6 (S)-methylmalonyl-CoA + 12 H(+) + malonyl-CoA + 5 NADPH


name: GOPC promotes translocation of CFTR to lysosomes (Bos taurus)


name: NTPDase3 hydrolyzes nucleoside triphosphates (Bos taurus)


name: 11-cis-retinol + NADP(+) = 11-cis-retinal + H(+) + NADPH


name: 4-chlorocatechol + NAD(+) + nitrite => 1-chloro-3-nitrobenzene + NADH + O2


name: KAL1 binds FGFR1c (Caenorhabditis elegans)


name: ATP + dGMP + L-aspartate => (2S)-2-amino-2'-deoxyadenylo-succinate + ADP + 2 H(+) + phosphate


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Saccharomyces cerevisiae)


name: Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor (Mus musculus)


name: H2O + quercitrin => L-rhamnopyranose + quercetin


name: NADP(+) + sulfinamide glutathione => H(+) + NADPH + S-nitrosoglutathione


name: 4-methylsulfanyl-2-oxobutanoate + L-glutamate => 2-oxoglutarate + L-methionine


name: Binding of RRN3 to RNA Polymerase I (Schizosaccharomyces pombe)


name: Hemes:LY96 activates TLR4 (Homo sapiens)


name: 3-dehydroquinate = 3-dehydroshikimate + H2O


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Homo sapiens)


name: 2-oxoglutarate + CO2 => (S)-oxalosuccinate + H(+)


name: Expression of ADP-ribosylation factor 1 (Homo sapiens)


name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Homo sapiens)


name: B4GALTs transfer Gal to the keratan chain (Sus scrofa)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Drosophila melanogaster)


name: Fibulin binds elastic fibres (Sus scrofa)


name: adenosine 3',5'-bisphosphate + androsterone 3alpha-sulfate + H(+) => 3'-phosphoadenylyl sulfate + androsterone


name: ATG3 transfers LC3 from ATG7 to ATG3 (Plasmodium falciparum)


name: ALOX15 oxidises DHA to 17(S)-Hp-DHA (Mus musculus)


name: a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP => a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose


name: adenine(in) + H(+)(in) <=> adenine(out) + H(+)(out)


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Bos taurus)


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Saccharomyces cerevisiae)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Bos taurus)


name: N-demethylindolmycin + S-adenosyl-L-methionine => H(+) + indolmycin + S-adenosyl-L-homocysteine


name: L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Neuroglobin binds oxygen (Canis familiaris)


name: acetyl-CoA + 10 H(+) + holo-[polyketide synthase] + 5 malonyl-CoA + 5 NADPH = 5 CO2 + 6 CoA + dodecapentaneoyl-[polyketide synthase] + 5 H2O + 5 NADP(+)


name: p-VAV family:PIP3 binds RAC1:GDP (Homo sapiens)


name: Defective DHDDS does not elongate E,E-FPP (Homo sapiens)


name: CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 (Gallus gallus)


name: Transport of L1 into endosomes (Mus musculus)


name: RFC dissociates after sliding clamp formation (Plasmodium falciparum)


name: (S)-2,3-diaminopropanoate + H(+) + H2O => 2 NH4(+) + pyruvate


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Sus scrofa)


name: RHOV binds effectors at the plasma membrane (Bos taurus)


name: Sustained activation of SRC kinase by SHP2 (Drosophila melanogaster)


name: ADP + beta-D-fructose 1,6-bisphosphate + H(+) => ATP + beta-D-fructose 1-phosphate


name: malonyl-CoA + S-adenosyl-L-methionine <=> malonyl-CoA methyl ester + S-adenosyl-L-homocysteine


name: Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX (Sus scrofa)


name: H(+) + hexadecanoyl-CoA + malonyl-CoA <=> 3-oxooctadecanoyl-CoA + CO2 + CoA


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Mus musculus)


name: (2-aminoethyl)phosphonate + pyruvate => L-alanine + phosphonoacetaldehyde


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Caenorhabditis elegans)


name: acetoacetyl-CoA + L-glutamate => (3S)-3-aminobutanoyl-CoA + 2-oxoglutarate


name: 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA (Homo sapiens)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Xenopus tropicalis)


name: 2-oxobutanoate + H(+) + pyruvate <=> (S)-2-ethyl-2-hydroxy-3-oxobutanoate + CO2


name: RhCG mediates ammonium influx into kidney collecting duct cells (Drosophila melanogaster)


name: H(+) + oxidized [electron-transfer flavoprotein] + valproyl-CoA <=> (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Danio rerio)


name: albaflavenone + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => (5S)-albaflavenol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + H2O = 1-O-hexadecyl-sn-glycerol + acetate + H(+)


name: PP6-PPP6R3 dephosphorylates TERF2 (Rattus norvegicus)


name: methylazoxymethanol + UDP-alpha-D-glucose => cycasin + H(+) + UDP


name: a dipeptide(out) + H(+)(out) = a dipeptide(in) + H(+)(in)


name: EGR2 (KROX20) activates HOXA2 expression (Homo sapiens)


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: AMP + L-threonyl-[peptidyl-carrier protein] => holo-[peptidyl-carrier protein] + L-threonyl-5'-AMP


name: BMAL1 binds CLOCK,NPAS2 forming BMAL1:CLOCK,NPAS2 heterodimer (Homo sapiens)


name: D-ribulose 5-phosphate <=> ribose 5-phosphate (Dictyostelium discoideum)


name: D-cellotetraono-1,5-lactone + H2O = D-cellotetraonate + H(+)


name: 2-hydroxyadipate + NAD(+) => 2-oxoadipate + H(+) + NADH


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Drosophila melanogaster)


name: p-S400-Cot phosphorylates NIK (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + H(+) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O


name: CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate => acetyl-CoA + alpha-D-glucosamine 1-phosphate


name: 3'-phosphoadenylyl sulfate + cholesterol <=> adenosine 3',5'-bisphosphate + cholesterol sulfate + H(+)


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Bos taurus)


name: PARK2 autoubiquitinates (Rattus norvegicus)


name: cytidine(62) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(62) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)


name: (9Z,12Z)-octadecadienoyl-CoA + A + 2 H2O => (9Z)-octadecenoyl-CoA + AH2 + O2


name: H(+) + trilobatin + UDP => phloretin + UDP-alpha-D-glucose


name: (3R)-hydroxy-(5Z)-dodecenoyl-[ACP] => (2E,5Z)-dodecadienoyl-[ACP] + H2O


name: SEMA4D interacts with CD45 (Mus musculus)


name: indole-3-pyruvate + L-kynurenine = H2O + kynurenate + L-tryptophan


name: NOTCH2-ligand complex is cleaved to produce NEXT2 (Homo sapiens)


name: 4-methylene-L-glutamine + H2O = 4-methylene-L-glutamate + NH4(+)


name: cyclo(L-leucyl-L-leucyl) + 4 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] + pulcherriminic acid


name: ganoderate TR + O2 + reduced [NADPH--hemoprotein reductase] <=> ganoderate Jc + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an acyl-CoA + cholesterol => a cholesterol ester + CoA


name: hexadecanoyl-CoA + octadecan-1-ol <=> CoA + octadecanyl hexadecanoate


name: Thrombin-activated PARs binds G-protein Gq (Caenorhabditis elegans)


name: creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Homo sapiens)


name: DHAP is converted to G3P by GPD1/GPD1L (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycerol <=> a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: pexidartinib-resistant FLT3 mutants don't bind pexidartinib (Homo sapiens)


name: 4-amino-4-deoxychorismate <=> 4-aminobenzoate + H(+) + pyruvate


name: 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + H(+) + NADH


name: Translocation of COP1 from the nucleus to the cytoplasm (Canis familiaris)


name: LDHAL6B reduces PYR to LACT (Xenopus tropicalis)


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+) => 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + NADPH


name: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)


name: Phosphorylation of Cyclin A:Cdk2 at Tyr 15 (Sus scrofa)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Caenorhabditis elegans)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Bos taurus)


name: 20-hydroxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: histidine => urocanate + NH4+ (Caenorhabditis elegans)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Bos taurus)


name: (2E)-eicosenoyl-CoA + H2O => (3R)-hydroxyeicosanoyl-CoA


name: butan-1-ol + 2 Fe(III)-[cytochrome c] => butanal + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: BTNL9 binds immune cell surfaces (Xenopus tropicalis)


name: 1'-hydroxyversicolorone + H(+) + NADPH + O2 => (2S,3S)-versiconal hemiacetal acetate + H2O + NADP(+)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate => (+)-5-epi-aristolochene + diphosphate


name: histone H3K72 acetyltransferase activity


name: ADBRK1,2 phosphorylate AVPR2 (Homo sapiens)


name: sGC stimulators bind sGC:NO (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol => 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: (E)-ferulate + ATP + H(+) => (E)-feruloyl-AMP + diphosphate


name: G alpha (z) inhibits adenylate cyclase (Homo sapiens)


name: Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane (Homo sapiens)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Mus musculus)


name: H2O + L-fucono-1,5-lactone => H(+) + L-fuconate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate


name: O2 + pregnenolone + reduced [NADPH--hemoprotein reductase] = 17alpha-hydroxypregnenolone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: UCHL3, SENP8 cleave NEDD8 (Homo sapiens)


name: 2-(3-methylsulfanyl)propylmalate => 2-(2-methylsulfanyl)propylmaleate + H2O


name: Phosphorylated AP-1, Phospho JRA:Phospho KAY dissociates from CKA (Drosophila melanogaster)


name: Phosphorylation of STAT1 by JAK kinases (Homo sapiens)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Caenorhabditis elegans)


name: α2-agonists bind ADRA2A,B,C (Sus scrofa)


name: 3-dehydro-6-deoxoteasterone + NADP(+) => (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + NADPH


name: ISGylation of E2 conjugating enzymes (Caenorhabditis elegans)


name: Noradrenaline clearance from the synaptic cleft (Mus musculus)


name: CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 (Xenopus tropicalis)


name: ADP + H(+) + N-acyl-15-methylhexadecasphing-4-enine-1-phosphate => ATP + N-acyl-15-methylhexadecasphing-4-enine


name: ATP + L-aspartate + NH4(+) = AMP + diphosphate + H(+) + L-asparagine


name: inositol tetrakisphosphate 6-kinase activity


name: Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Xenopus tropicalis)


name: L-threitol + NAD(+) = H(+) + L-erythrulose + NADH


name: RNF181 polyubiquinates BCL10 (Bos taurus)


name: p-T,Y MAPK dimers translocate to nucleus (Bos taurus)


name: Formation of MHC I:Nef Complex (Homo sapiens)


name: PP6-PPP6R3 dephosphorylates TERF2 (Bos taurus)


name: a quinone + H(+) + NADH <=> a quinol + NAD(+)


name: Defective GYG1 is not autoglucosyolated (Homo sapiens)


name: 1D-myo-inositol 1,4-bisphosphate + H2O <=> 1D-myo-inositol 4-phosphate + phosphate


name: D-galactonate(in) + H(+)(in) <=> D-galactonate(out) + H(+)(out)


name: ADBRK1,2 phosphorylate AVPR2 (Xenopus tropicalis)


name: 5-phosphomethyl-dUMP in DNA + L-serine => 5-O-(L-seryl)-dTMP in DNA + phosphate


name: an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Xenopus tropicalis)


name: 2 ATP + butan-2-one + 3 H2O + hydrogencarbonate => 3-oxopentanoate + 2 AMP + 4 H(+) + 4 phosphate


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Homo sapiens)


name: AIR + CO2 => CAIR (Caenorhabditis elegans)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Rattus norvegicus)


name: Phosphorylation of TEC kinases by p-SYK (Canis familiaris)


name: a (Z)-N-(sulfonatooxy)alkanimidothioate => a nitrile + sulfate + sulfur


name: RHOD:GTP translocates to the endosome membrane (Homo sapiens)


name: ATP + H2O + L-glutamine(out) => ADP + H(+) + L-glutamine(in) + phosphate


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 11alpha-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Canis familiaris)


name: Formation of MSH2:MSH3 Complex (Gallus gallus)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Canis familiaris)


name: STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Mus musculus)


name: HSPG2 (perlecan) binds alpha-dystroglycan (Drosophila melanogaster)


name: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Rattus norvegicus)


name: ITSN1 exchanges GTP for GDP on CDC42, activating it (Homo sapiens)


name: dGDP + H(+) + phosphoenolpyruvate => dGTP + pyruvate


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] => atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Xenopus tropicalis)


name: a 2,4-dihydroxypteridine + NH4(+) => a 2-amino-4-hydroxypteridine + H(+) + H2O


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + CoA + H(+)


name: 5-nitroanthranilate + H(+) + H2O = 5-nitrosalicylate + NH4(+)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Bos taurus)


name: glycerol 1-phosphate + H2O = glycerol + phosphate


name: TP53 stimulates expression of SESN1,2,3 genes (Homo sapiens)


name: (S)-canadine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (S)-tetrahydrocolumbamine + O2 + reduced [NADPH--hemoprotein reductase]


name: Integrin alphaIIb beta3 activation (Canis familiaris)


name: ent-copalyl diphosphate <=> diphosphate + ent-kaur-16-ene


name: inositol tetrakisphosphate 2-kinase activity


name: Beta-defensins bind microbial membranes causing disruption (Rattus norvegicus)


name: CBY1 binds beta-catenin (Rattus norvegicus)


name: Recruitment of VAV to p-SLP-76 (Mus musculus)


name: decanoyl-CoA + H2O => adenosine 3',5'-bisphosphate + decanoyl-4'-phosphopantetheine + 2 H(+)


name: chloride(out) + L-threonine(out) + 2 Na(+)(out) <=> chloride(in) + L-threonine(in) + 2 Na(+)(in)


name: RAP1A exchanges GDP for GTP (Rattus norvegicus)


name: HJURP:CENPA complex localizes to the centromere (Canis familiaris)


name: acetyl-CoA + N-terminal L-methionyl-[tubulin] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Canis familiaris)


name: USP48 cleaves polyubiquitin (Bos taurus)


name: 5-methyl-CMP + diphosphate + H(+) => 5-methyl-CTP + H2O


name: Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Sus scrofa)


name: adenosylcob(III)inamide-GDP + diphosphate => adenosylcob(III)inamide phosphate + GTP + H(+)


name: EPCAM binds itself to form homotypic cell adhesion (Bos taurus)


name: Opsins act as GEFs for G alpha-t (Sus scrofa)


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Rattus norvegicus)


name: an ultra-long-chain di-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxo-ultra-long-chain di-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: "meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II"


name: [aequorin]--dioxetanone = [excited state blue fluorescent protein] + CO2


name: (S)-3-hydroxybutanoate + 2-oxoglutarate => (R)-2-hydroxyglutarate + acetoacetate


name: CO2 + NADPH + pyruvate => (S)-malate + NADP(+)


name: (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one + H(+) + NADPH => 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP(+)


name: (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O


name: L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + UDP-alpha-D-glucose = alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) + UDP


name: CDC6 association with ORC(1-6) at replication origins (Canis familiaris)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate => goitrin + sulfate


name: mature p21 RAS binds GDP (Caenorhabditis elegans)


name: ATP + H(+) + L-glutamate => diphosphate + L-glutamyl-5'-AMP


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Canis familiaris)


name: 1-methyladenine + a 2'-deoxyribose 5'-phosphate in double-stranded DNA + H(+) => an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + H2O


name: p-S MAPKAPK5 phosphorylates HSPB1 (Mus musculus)


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Rattus norvegicus)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Caenorhabditis elegans)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Mus musculus)


name: p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Sus scrofa)


name: AKT phosphorylates FOXO1A (Gallus gallus)


name: D-ribose 2,5-bisphosphate + H2O = D-ribose 5-phosphate + phosphate


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Sus scrofa)


name: G-protein beta-gamma subunits rebind the alpha-GDP subunit (Canis familiaris)


name: VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Homo sapiens)


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Gallus gallus)


name: Expression of ABCG5 regulated by NR1H2,3 (Homo sapiens)


name: Interaction of integrin alpha8beta1 with Tenascin-C (Rattus norvegicus)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Bos taurus)


name: EDNRA binds selective ERAs (Rattus norvegicus)


name: H2O + L-2-aminopentanoate + NAD(+) => 2-oxopentanoate + H(+) + NADH + NH4(+)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Drosophila melanogaster)


name: p-Y705-STAT3, p-Y641-STAT6 dimerise (Drosophila melanogaster)


name: 3-sulfopyruvate + H(+) <=> CO2 + sulfoacetaldehyde


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Homo sapiens)


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Gallus gallus)


name: ATP + H2O + L-methionine(out) <=> ADP + H(+) + L-methionine(in) + phosphate


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: H2O + L-selenocystathionine => 2-oxobutanoate + L-selenocysteine + NH4(+)


name: 4-hydroxybenzaldehyde + hydrogen cyanide => (S)-4-hydroxymandelonitrile


name: a glycerophospholipid + H2O <=> a 1-acyl-sn-glycero-3-phospholipid + a fatty acid + H(+)


name: 3,4-dihydroxypyridine + O-acetyl-L-serine => 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate + H(+)


name: 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-dodecanoylglycerol


name: USP8 deubiquitinates STAM2:HGS (Homo sapiens)


name: levoglucosan + NAD(+) <=> 3-dehydrolevoglucosan + H(+) + NADH


name: NFE2 binds the beta globin locus control region (Mus musculus)


name: TRPV1 binds TRPV1 agonists (Saccharomyces cerevisiae)


name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Rattus norvegicus)


name: methyl salicylate + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + salicylate


name: acrylate + 2 H(+) + NADH => acrolein + H2O + NAD(+)


name: benzoyl-AMP + CoA => AMP + benzoyl-CoA + H(+)


name: Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Rattus norvegicus)


name: ALOX5 oxidises DHA to 7-HDHA (Danio rerio)


name: NPM1 binds TFAP2A homodimer (Xenopus tropicalis)


name: dimethyl sulfide + H(+) + NADH + O2 <=> dimethyl sulfoxide + H2O + NAD(+)


name: 17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP => 17beta-estradiol + UDP-alpha-D-glucuronate


name: Receptor FFAR1 binds free fatty acids (Bos taurus)


name: Dissociation of Cdc20 from APC/C complex (Sus scrofa)


name: NADP(+) + tropine <=> H(+) + NADPH + tropinone


name: erythromycin C + S-adenosyl-L-methionine = erythromycin A + H(+) + S-adenosyl-L-homocysteine


name: 4-hydroxybenzoyl-5'-AMP + holo-[4-hydroxyphenylalkanoate synthase] => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + H(+)


name: chenodeoxycholoyl-CoA + taurine => CoA + H(+) + taurochenodeoxycholate


name: SRC-1 phosphorylates PTK2-beta (Canis familiaris)


name: WIPI2 binds ATG12:ATG5:ATG16L (Drosophila melanogaster)


name: LIPT2 transfers octanoyl group to GCSH (Rattus norvegicus)


name: acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative => an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O


name: USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Saccharomyces cerevisiae)


name: SBF1 binds MTMR2 (Dictyostelium discoideum)


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Danio rerio)


name: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) <=> (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA => 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Gallus gallus)


name: (E)-caffeyl aldehyde + CoA + NADP(+) => (E)-caffeoyl-CoA + H(+) + NADPH


name: (6S)-5,6,7,8-tetrahydropteroate + NAD(+) = 7,8-dihydropteroate + H(+) + NADH


name: FUT2 transfers Fuc to LeX to form LeY (Caenorhabditis elegans)


name: UBF-1 Binds rDNA Promoter (Xenopus tropicalis)


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Drosophila melanogaster)


name: 2'-dehydrokanamycin A + H(+) + NADPH <=> kanamycin A + NADP(+)


name: geranylgeranyl diphosphate = beta-araneosene + diphosphate


name: dodecanoyl-CoA + FAD + H(+) => (2E)-dodecenoyl-CoA + FADH2


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Xenopus tropicalis)


name: Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Canis familiaris)


name: (25R)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (25R)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: DHFR dimer reduces FOLA to DHF (Sus scrofa)


name: Association of procollagen type XXVI (Canis familiaris)


name: ATP + D-glycero-alpha-D-manno-heptose 7-phosphate = ADP + D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + H(+)


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Mus musculus)


name: dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate


name: 4-methylsulfanyl-2-oxobutanoate + H(+) + NADPH => (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NADP(+)


name: Dephosphorylation of p107 (RBL1) by PP2A (Bos taurus)


name: ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE (Sus scrofa)


name: (2E)-geranyl diphosphate + isopentenyl diphosphate => (2Z,6E)-farnesyl diphosphate + diphosphate


name: P2X1-mediated entry of Ca++ from plasma (Gallus gallus)


name: CYP2W1 oxidises INDOL (Rattus norvegicus)


name: (2-aminoethyl)phosphonate + acetyl-CoA => (2-acetamidoethyl)phosphonate + CoA + H(+)


name: a menaquinone + 2 H(+) + 2 superoxide => a menaquinol + 2 O2


name: (9Z,12Z)-octadecadienoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol <=> 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Mus musculus)


name: 7,8-dihydroneopterin + phosphate <=> 7,8-dihydroneopterin 3'-phosphate + H2O


name: Depolymerization of lamin filaments after PKC-mediated phosphorylation (Sus scrofa)


name: FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer (Bos taurus)


name: Activation of EPACs by cAMP (Saccharomyces cerevisiae)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Schizosaccharomyces pombe)


name: (2E,6E)-farnesyl diphosphate => alpha-longipinene + diphosphate


name: 5,6-dihydrouracil + 5-phospho-alpha-D-ribose 1-diphosphate => 5,6-dihydrouridine 5'-monophosphate + diphosphate


name: 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + H(+) + S-methyl-5'-thioadenosine => 4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine


name: H2O + N-(4-aminobenzoyl)-L-glutamate => 4-aminobenzoate + L-glutamate


name: ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Homo sapiens)


name: Phosphorylation and activation of CHEK2 by ATM (Bos taurus)


name: UCKL1 phosphorylates urindine, cytidine (Sus scrofa)


name: RNF8 and RNF168 ubiquitinate H2AFX (Rattus norvegicus)


name: dauca-4,7-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = asperaculane D + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 15-oxoprostaglandin E2 + H(+) + NADPH => NADP(+) + prostaglandin E2


name: PTPN3 dephosphorylates MAPK12 (Homo sapiens)


name: delphinidin + UDP-alpha-D-glucose => delphinidin 3-O-beta-D-glucoside + UDP


name: CO2 + H2O + indole-3-acetamide => L-tryptophan + O2


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Xenopus tropicalis)


name: 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 27 H(+) + 9 malonyl-CoA + 18 NADPH = 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate synthase] + 9 CO2 + 9 CoA + 9 H2O + 18 NADP(+)


name: L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu)


name: PIAS2,3,4 SUMOylate RORA with SUMO2 (Danio rerio)


name: Endosome acidification (Canis familiaris)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Mus musculus)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A (E. coli) => a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate) (E. coli)


name: H(+)(in) + L-alanine(in) => H(+)(out) + L-alanine(out)


name: ARHGAP39 (Vilse) binds ROBO1:SLIT2 (Homo sapiens)


name: CoA + ergosteryl ester => an acyl-CoA + ergosterol


name: D-glyceraldehyde + H2O + NADP(+) => (R)-glycerate + 2 H(+) + NADPH


name: phosphate + presqualene alcohol => H2O + presqualene monophosphate


name: 2 a quinone + H(+) + NADPH <=> 2 a 1,4-benzosemiquinone + NADP(+)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Dictyostelium discoideum)


name: benzyl isothiocyanate => benzyl thiocyanate


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Bos taurus)


name: 5beta-androstane-3,17-dione + H(+) + NADPH = 3beta-hydroxy-5beta-androstane-17-one + NADP(+)


name: 3'-phosphoadenylyl sulfate + tauro-alpha-muricholate => adenosine 3',5'-bisphosphate + H(+) + tauro-alpha-muricholate 7-sulfate


name: gibberellin A4 + S-adenosyl-L-methionine <=> O-methyl gibberellin A4 + S-adenosyl-L-homocysteine


name: ATP + streptomycin <=> ADP + H(+) + streptomycin 3''-phosphate


name: Fibulin-1 and -2 bind fibronectin (Canis familiaris)


name: p-PKR dimer phosphorylates DHX9 (Caenorhabditis elegans)


name: 6-oxocineole + H(+) + NADPH + O2 => 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H2O + NADP(+)


name: PSD-95 binds NMDA receptor (Homo sapiens)


name: PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: Assembly of the anterograde IFT train (Bos taurus)


name: [PrdC protein]-L-selenocysteine/L-cysteine + D-proline => 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine


name: RAC1 and CDC42 activate PAK2 (Dictyostelium discoideum)


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Sus scrofa)


name: Activated FGFR3 phosphorylates PLCG1 (Bos taurus)


name: a long-chain fatty aldehyde + holo-[ACP] + NADP(+) => a long-chain fatty acyl-[ACP] + H(+) + NADPH


name: RHOT2 binds effectors at the mitochondrial outer membrane (Rattus norvegicus)


name: (7S)-O-acetylsalutaridinol + CoA => (7S)-salutaridinol + acetyl-CoA


name: Phosphorylation of INFAR1 by TYK2 (Gallus gallus)


name: HIPK2 phosphorylates RUNX1 (Mus musculus)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Xenopus tropicalis)


name: long-chain fatty acid transporting porin activity


name: (E)-cinnamate + O2 + reduced [NADPH--hemoprotein reductase] <=> (E)-4-coumarate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of P-TEFb complex (Rattus norvegicus)


name: a beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosaminyl derivative + H(+) + UDP => a beta-D-galactosyl-(1->4)-beta-D-glucosyl derivative + UDP-alpha-D-galactose


name: O2 + oleanolic aldehyde + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + oleanolate + oxidized [NADPH--hemoprotein reductase]


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Mus musculus)


name: estrone 4-O-(beta-D-glucuronate) + H(+) + UDP => 4-hydroxyestrone + UDP-alpha-D-glucuronate


name: 12,13-epoxy-(9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-12,13-epoxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Rattus norvegicus)


name: IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Bos taurus)


name: ATP + D-mannose = ADP + D-mannose 6-phosphate + H(+)


name: XYLB phosphorylates D-xylulose (Homo sapiens)


name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Saccharomyces cerevisiae)


name: ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate => ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate


name: RAC2 GDIs block activation of RAC2 (Homo sapiens)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 => 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate


name: a jasmonyl-L-amino acid + AMP + diphosphate + H(+) => a jasmonate + an L-alpha-amino acid + ATP


name: NUBPL transfers 4Fe-4S to Complex I subunits (Homo sapiens)


name: H2O + trimetaphosphate <=> 2 H(+) + triphosphate


name: Mitochondrial recruitment of Drp1 (Rattus norvegicus)


name: PKA phosphorylates PDE4B (Gallus gallus)


name: botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: D-fuconate <=> 2-dehydro-3-deoxy-D-fuconate + H2O


name: ERK1/2 phosphorylates MSK1 (Homo sapiens)


name: RB1 translocates to the nucleus (Sus scrofa)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Schizosaccharomyces pombe)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Homo sapiens)


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Homo sapiens)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Gallus gallus)


name: ent-copalyl diphosphate = diphosphate + ent-pimara-8(14),15-diene


name: 1-O-alkyl-sn-glycero-3-phosphate + choline + H(+) => 1-O-alkyl-sn-glycero-3-phosphocholine + H2O


name: 27-O-demethylrifamycin SV + S-adenosyl-L-methionine = H(+) + rifamycin SV + S-adenosyl-L-homocysteine


name: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside <=> L-fucose + methyl beta-D-galactoside


name: chloride(out) + 2 hydrogencarbonate(in) + Li(+)(in) = chloride(in) + 2 hydrogencarbonate(out) + Li(+)(out)


name: ATP + L-glutamine + tRNA(Gln) => AMP + diphosphate + L-glutaminyl-tRNA(Gln)


name: 3-phenylpyruvate + O2 = (2-hydroxyphenyl)acetate + CO2


name: (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: FGFR1c binds to Klotho-bound FGF23 (Homo sapiens)


name: Rsu-1 interacts with Pinch1 (Mus musculus)


name: USP12, USP26 deubiquitinate AR (Xenopus tropicalis)


name: (3S)-hydroxytetradecanoyl-CoA + H2O = (3S)-hydroxytetradecanoate + CoA + H(+)


name: transferase activity, transferring one-carbon groups


name: Elongation of pre-rRNA transcript (Canis familiaris)


name: FITM1, FITM2 bind TAGs (Canis familiaris)


name: Cleavage of hypoxanthine by MPG glycosylase (Mus musculus)


name: 3-[(1-carboxyvinyl)-oxy]benzoate + H2O => chorismate


name: Cho is phosphorylated to PCho by CHK dimer (Sus scrofa)


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Mus musculus)


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Rattus norvegicus)


name: allocholate + lithocholoyl-CoA <=> allocholoyl-CoA + lithocholate


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Mus musculus)


name: PRC1 SUMOylates CTBP1 with SUMO2,3 (Drosophila melanogaster)


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Gallus gallus)


name: cortisol + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-phenylethylamine + H2O + O2 => 2-phenylacetaldehyde + H2O2 + NH4(+)


name: 6alpha-hydroxy-28-norcastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxo-28-norcastasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Bos taurus)


name: NOTCH1 PEST domain mutants coactivator complex binds CDK8:CCNC (Homo sapiens)


name: CO2 + hnu + oxidized Cypridina luciferin => Cypridina luciferin + O2


name: 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) = 8-epi-inunolide + H2O


name: H(+) + luteolin 7-O-beta-D-glucoside + UDP => luteolin + UDP-alpha-D-glucose


name: (E)-caffeoyl-CoA + H(+) + NADPH => (E)-caffeyl aldehyde + CoA + NADP(+)


name: an N-acylsphing-4-enine + CDP-choline <=> a sphingomyelin + CMP + H(+)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Saccharomyces cerevisiae)


name: PHGDH tetramer dehydrogenates 3PG (Xenopus tropicalis)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Homo sapiens)


name: glyceollin I + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-2-(7Z,10Z,13Z,16Z,19Z-docosapentaenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O = (9Z)-octadecenoate + 2-(7Z,10Z,13Z,16Z,19Z-docosapentaenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H(+)


name: (S)-8-oxocitronellyl enol <=> cis-cis-nepetalactol


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Homo sapiens)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Mus musculus)


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Mus musculus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (5Z,8Z,11Z)-eicosatrienoate => 1-hexadecanoyl-2-(5Z,8Z,11Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol


name: ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex (Homo sapiens)


name: SMURF2 binds SMAD2 (Drosophila melanogaster)


name: Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA (Drosophila melanogaster)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Mus musculus)


name: MAF1 translocates to the nucleus (Saccharomyces cerevisiae)


name: adenosine 3',5'-bisphosphate + H(+) + holo-[BtrI ACP] => apo-[BtrI ACP] + CoA


name: H2O + N-(9Z-octadecenoyl)-L-methionine => (9Z)-octadecenoate + L-methionine


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Gallus gallus)


name: 2',3'-cGAMP(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) = 2',3'-cGAMP(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: NEIL3 cleaves spiroiminodihydantoin from damaged telomeric DNA (Homo sapiens)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: 1-tetradecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: H2O + S-[(2E,6E,10E)-geranylgeranyl]-L-glutathione = L-glutamate + S-[(2E,6E,10E)-geranylgeranyl]-L-cysteinylglycine


name: A + a 1-hydroxy-3-oxo steroid => a steroid 1,3-dione + AH2


name: 2 L-ascorbate + N-dodecanoylglycine + O2 <=> H2O + 2 monodehydro-L-ascorbate radical + N-dodecanoyl-(2S)-hydroxyglycine


name: H(+) + O-phospho-L-threonine = (R)-1-aminopropan-2-yl phosphate + CO2


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Rattus norvegicus)


name: SLC25A10 mediates exchange of malate and phosphate (Bos taurus)


name: 4 L-ascorbate + O2 => 2 H2O + 4 monodehydro-L-ascorbate radical


name: SLCO2B1 has a narrow substrate specificity (Rattus norvegicus)


name: H(+) + L-methionyl(47)-[F-actin] + NADPH + O2 = H2O + L-methionyl(47)-(R)-S-oxide-[F-actin] + NADP(+)


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Saccharomyces cerevisiae)


name: WWTR1 (TAZ), TBX5, and PCAF form a complex (Caenorhabditis elegans)


name: Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha  (Danio rerio)


name: C3b fragment binds to the target cell surface (Gallus gallus)


name: Active ALK dimer binds IRS1 (Sus scrofa)


name: 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH => 5alpha-androstane-3alpha,17beta-diol + NADP(+)


name: Collagen type XIII ectodomain shedding (Sus scrofa)


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate => (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2


name: vWF binds to collagen (Canis familiaris)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Mus musculus)


name: beta-D-galactose + N-hexadecanoylsphing-4-enine => beta-D-galactosyl-(1<->1')-N-hexadecanoylsphingosine + H2O


name: ATP + H2O + taurodeoxycholate(in) <=> ADP + H(+) + phosphate + taurodeoxycholate(out)


name: 2-oxoglutarate(in) + 3 Na(+)(in) => 2-oxoglutarate(out) + 3 Na(+)(out)


name: A + H2O + resolvin E2 => (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N(omega)-hydroxy-L-arginine = 2 Fe(III)-[cytochrome b5] + H2O + L-arginine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate


name: 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol + 2 Fe(III)-[cytochrome b5] + H2O


name: (6aR,11aR)-3,9-dihydroxypterocarpan + H2O => (3R,4R)-7,2',4'-trihydroxyisoflavanol


name: Autophosphorylation of BTK/ITK (Gallus gallus)


name: HRSP12 deaminates 2AA to 2OBUTA (Danio rerio)


name: trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Rattus norvegicus)


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Plasmodium falciparum)


name: (3R,4S,5S,6R)-pentachlorocyclohexene + chloride + H(+) => gamma-hexachlorocyclohexane


name: Part of pro-beta-NGF is processed to mature beta-NGF (Danio rerio)


name: 3-dehydro-D-erythronate + ATP => 3-dehydro-4-O-phospho-D-erythronate + ADP + H(+)


name: (+)-beta-selinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine <=> [LarE protein]-dehydroalanine + H(+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: ADP-D-ribose + L-asparaginyl-[protein] => H2O + N(4)-(ADP-D-ribosyl)-L-asparaginyl-[protein]


name: ADIPOQ trimer binds ADIPOR dimers (Bos taurus)


name: GDP-beta-L-fucose + L-seryl-[EGF-like domain protein] => 3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + GDP + H(+)


name: a dolichyl diphosphate + H(+) + N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginy-[protein] => a dolichyl diphosphooligosaccharide + L-asparaginyl-[protein]


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Caenorhabditis elegans)


name: RSV ssRNA binds C-ter TLR7 dimer (Homo sapiens)


name: 4-hydroxyphenylacetonitrile + O2 + reduced [NADPH--hemoprotein reductase] => (S)-4-hydroxymandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Homo sapiens)


name: 3 (S)-methylmalonyl-CoA + a long-chain fatty acyl-CoA + 9 H(+) + holo-[mycolipanoate synthase] + 6 NADPH = 3 CO2 + 4 CoA + 3 H2O + long-chain mycolipanoyl-[mycolipanoate synthase] + 6 NADP(+)


name: H(+)(in) + L-alanine(out) + Na(+)(out) => H(+)(out) + L-alanine(in) + Na(+)(in)


name: Beclin-1 complex phosphorylates PtdIns (Schizosaccharomyces pombe)


name: alpha-D-galactose 1-phosphate + H2O => D-galactose + phosphate


name: p-4Y-SIRPA:CD47 binds SKAP2 (Canis familiaris)


name: ZnT8 transports zinc into the Golgi apparatus (Rattus norvegicus)


name: acetylcholine + H2O => acetate + choline + H(+)


name: Docking of Mature Histone mRNA complex:TAP at the NPC (Rattus norvegicus)


name: M2 mRNA is translated into protein M2-2 (Homo sapiens)


name: Dephosphorylation of JAKs by PTPs (Homo sapiens)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Rattus norvegicus)


name: (3R)-3-isocyanylbutanoyl-AMP + diphosphate => (3R)-3-isocyanylbutanoate + ATP + H(+)


name: TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) (Homo sapiens)


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)


name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Homo sapiens)


name: G alpha (q) in G (q):RGS complex is inactivated (Xenopus tropicalis)


name: 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O <=> (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + catechol + H(+)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Bos taurus)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: TBC1D25 (OATL1) binds ATG8 homologues (Drosophila melanogaster)


name: H(+) + prop-2-ynal + pyrroloquinoline quinol = prop-2-yn-1-ol + pyrroloquinoline quinone


name: dGMP + H2O => 2'-deoxyguanosine + phosphate


name: 4 AH2 + all-trans-4,4'-diapolycopene + 4 O2 = 4 A + all-trans-4,4'-diapolycopene-4,4'-dial + 6 H2O


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Bos taurus)


name: 4-nitro-6-oxohepta-2,4-dienedioate = 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite


name: (9Z)-tetradecenoate + ATP + CoA <=> (9Z)-tetradecenoyl-CoA + AMP + diphosphate


name: apigenin + S-adenosyl-L-methionine => acacetin + H(+) + S-adenosyl-L-homocysteine


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Bos taurus)


name: 3-dehydro-D-glucose 6-phosphate + H(+) + NADH => D-glucose 6-phosphate + NAD(+)


name: an N-acyl-D-aspartate + H2O => a carboxylate + D-aspartate


name: 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: ATP + CoA + decanedioate => AMP + decanedioyl-CoA + diphosphate


name: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP => di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Dictyostelium discoideum)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Rattus norvegicus)


name: LONP1 binds mitochondrial matrix proteins (Drosophila melanogaster)


name: C-C motif chemokine 19 receptor activity


name: H(+) + oxidized [electron-transfer flavoprotein] + pentanoyl-CoA = (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]


name: Autophosphorylation of PAK1,2,3 (Saccharomyces cerevisiae)


name: a 5'-end ribonucleotide-RNA + a ribonucleoside 5'-triphosphate + ATP + H2O => a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + AMP + 2 diphosphate + H(+)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Mus musculus)


name: LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Drosophila melanogaster)


name: 7(1)-hydroxychlorophyll a + NADP(+) <=> chlorophyll b + H(+) + NADPH


name: Association of Securin with Cdc20:APC/C complex (Xenopus tropicalis)


name: The 60S subunit joins the translation initiation complex  (Sus scrofa)


name: L-aspartate(in) + sulfate(out) <=> L-aspartate(out) + sulfate(in)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Bos taurus)


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Rattus norvegicus)


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Rattus norvegicus)


name: UHRF1:Chromatin binds DNMT1 (Homo sapiens)


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA => (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphate


name: REST binds promoter and the first intron of NPAS4 gene (Homo sapiens)


name: lithocholate + ursodeoxycholoyl-CoA => lithocholoyl-CoA + ursodeoxycholate


name: 9-cis-retinol + NAD(+) => 9-cis-retinal + H(+) + NADH


name: 5-hydroxypentan-2-one + H(+) + NADH + NH4(+) => 5-hydroxypentan-2-amine + H2O + NAD(+)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Bos taurus)


name: RHOD binds effectors at the mitochondrial outer membrane (Saccharomyces cerevisiae)


name: Acitretin binds to RAR:RXR (Canis familiaris)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Bos taurus)


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Schizosaccharomyces pombe)


name: Addition of nucleotides leads to transcript elongation (Drosophila melanogaster)


name: DAG kinase produces phosphatidic acid from DAG (Plasmodium falciparum)


name: ATP + H2O + indoxyl sulfate(in) => ADP + H(+) + indoxyl sulfate(out) + phosphate


name: 1D-myo-inositol 3,4,6-trisphosphate + ATP <=> 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H(+)


name: H2O + methyl (-)-jasmonate <=> H(+) + jasmonate + methanol


name: 2-oxoglutarate + pyridoxamine 5'-phosphate = D-glutamate + pyridoxal 5'-phosphate


name: GLB1 hydrolyses a glycosaminoglycan (Drosophila melanogaster)


name: AH2 + O2 + pregna-4,9(11)-diene-3,20-dione => 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Bos taurus)


name: Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV (Sus scrofa)


name: H2O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)


name: 2,7-dihydroxy-5-methyl-1-naphthoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2-hydroxy-5-methyl-1-naphthoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Association of Cks1 with SCF(Skp2) complex (Bos taurus)


name: 8-oxo-dATP + H2O = 8-oxo-dAMP + diphosphate + H(+)


name: NADPH + (n+1) sulfur => hydrogen sulfide + NADP(+) + n sulfur


name: Recruitment of TRAF6 to CBM complex by binding to MALT1 (Rattus norvegicus)


name: Binding of Grb10 to the insulin receptor (Mus musculus)


name: Proinsulin translocates from the endoplasmic reticulum to the Golgi (Gallus gallus)


name: atROL binds RBP1 to form RBP1:atROL (Caenorhabditis elegans)


name: dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Caenorhabditis elegans)


name: PROT mediates L-proline uptake (Caenorhabditis elegans)


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Canis familiaris)


name: H(+)(out) + L-alanyl-L-prolylglycine(out) = H(+)(in) + L-alanyl-L-prolylglycine(in)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Drosophila melanogaster)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2 => (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Danio rerio)


name: ISGylation of E2 conjugating enzymes (Rattus norvegicus)


name: RHOB GAPs stimulate RHOB GTPase activity (Rattus norvegicus)


name: (1R,4R)-camphor + H(+) + NADH => (1R,2S,4R)-borneol + NAD(+)


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Xenopus tropicalis)


name: 7-deoxyloganin + H(+) + UDP => 7-deoxyloganetin + UDP-alpha-D-glucose


name: ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (Homo sapiens)


name: InlB promotes MET dimerization (Homo sapiens)


name: Formation of MHC II alpha beta heterodimer (Rattus norvegicus)


name: GNLY binds the bacterial cell surface (Sus scrofa)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Sus scrofa)


name: PTEN undergoes monoubiquitination (Sus scrofa)


name: Factor H binds to membrane-associated C3b (Bos taurus)


name: MTMR4 dephosphorylates SMAD2/3 (Homo sapiens)


name: 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA (Homo sapiens)


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Sus scrofa)


name: coenzyme F420-0 gamma-glutamyl ligase activity


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Schizosaccharomyces pombe)


name: MSH2:MSH6 exchanges ADP for ATP (Dictyostelium discoideum)


name: Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+ (Homo sapiens)


name: 3 ATP <=> 2',3',3'-c-tri-AMP + 3 diphosphate


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + H(+) => 3,4-dihydroxybenzoyl-5'-AMP + holo-[aryl-carrier protein]


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 => (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate


name: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O => 2 beta-L-arabinofuranose


name: (2E,6E)-farnesyl diphosphate + H2O = avermitilol + diphosphate


name: a beta-D-galactoside + acetyl-CoA => a 6-acetyl-beta-D-galactoside + CoA


name: N-acetyl-L-aspartate(in) + 3 Na(+)(in) => N-acetyl-L-aspartate(out) + 3 Na(+)(out)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + H2O => [(1->4)-N-acetyl-beta-D-glucosaminyl](n-2) + N,N'-diacetylchitobiose


name: (R)-lactate + ATP + D-alanine = ADP + D-alanyl-(R)-lactate + phosphate


name: RAP1A exchanges GDP for GTP (Drosophila melanogaster)


name: Collagen type XXV ectomain shedding (Sus scrofa)


name: Caspase-3 cleaves pro-interleukin-16 (Canis familiaris)


name: 2-methoxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP => 2-methoxyestrone + UDP-alpha-D-glucuronate


name: CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex (Homo sapiens)


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)


name: 2-oxoglutarate + L-asparaginyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: D-ribulose 5-phosphate <=> ribose 5-phosphate (Xenopus tropicalis)


name: Activated MAPKs phosphorylate BRAF (Gallus gallus)


name: DNA-PK binds microbial dsDNA (Homo sapiens)


name: N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine


name: a dolichyl beta-D-mannosyl phosphate + H2O = a dolichyl phosphate + D-mannose + H(+)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Danio rerio)


name: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate


name: Addition of galactose to Core 6 glycoprotein (Gallus gallus)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Bos taurus)


name: MRE11 binds cytosolic DNA (Gallus gallus)


name: estrone 3-sulfate + H2O <=> estrone + H(+) + sulfate


name: acetyl-CoA + N-terminal L-methionyl-L-seryl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-seryl-[protein]


name: 1-hydroxy-6-methoxyphenazine + S-adenosyl-L-methionine = 1,6-dimethoxyphenazine + H(+) + S-adenosyl-L-homocysteine


name: MST1 dimer:MST1R dimer binds MST1R dimer (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: arsenate + 3 H(+) + 2 reduced [azurin] => arsenite + H2O + 2 oxidized [azurin]


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)


name: 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + spheroiden-2-one => 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spheroidene


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Caenorhabditis elegans)


name: CYP51A1 demethylates LNSOL (Danio rerio)


name: Autophosphorylation of BTK/ITK (Canis familiaris)


name: citrate(in) + maleate(out) => citrate(out) + maleate(in)


name: a medium-chain fatty aldehyde + H(+) + NADPH => a medium-chain primary fatty alcohol + NADP(+)


name: WWP2 ubiquitinates NOTCH3 (Homo sapiens)


name: (9Z)-octadecenoate + H(+) + holo-[ACP] => (9Z)-octadecenoyl-[ACP] + H2O


name: Activation of RAC1 by the PXN:CRK complex (Rattus norvegicus)


name: 4'''-demalonylsalvianin + malonyl-CoA = CoA + salvianin


name: "pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4'''-malonyltransferase"


name: 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+) => 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Caenorhabditis elegans)


name: P-type transmembrane transporter activity


name: ENPP7 hydrolyzes sphingomyelin (Dictyostelium discoideum)


name: (6R,7S)-himachala-9,11-diene + diphosphate => (2Z,6E)-farnesyl diphosphate


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Caenorhabditis elegans)


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Mus musculus)


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) <=> H(+) + NADPH + testosterone


name: Phosphorylation of IFNGR1 by JAK kinases (Gallus gallus)


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Canis familiaris)


name: SQSTM1 oligomer is phosphorylated (Homo sapiens)


name: (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate


name: guanosine(1370) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(1370) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Fe(III)-enterobactin + H(+) + 3 H2O <=> Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + 2 N-(2,3-dihydroxybenzoyl)-L-serine


name: PAKs phosphorylate MLC (Canis familiaris)


name: PKA/PKG phosphorylate Rap1GAP2 (Gallus gallus)


name: NEU1,4 hydrolyze PSAP(195-273):GM3:PE (Homo sapiens)


name: ATP + butanoate + H(+) + NADPH => AMP + butanal + diphosphate + NADP(+)


name: AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Gallus gallus)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Dictyostelium discoideum)


name: ALDH3A2-1 oxidises HD2NAL to PALM (Danio rerio)


name: 6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+) <=> 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH


name: H2O + quercetin 4'-O-beta-D-glucoside = beta-D-glucose + quercetin


name: N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: trans-Golgi Network Vesicle Scission (Mus musculus)


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Mus musculus)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Canis familiaris)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Mus musculus)


name: Dynamin is recruited to the gap junction plaque (Bos taurus)


name: ADP + H(+) + L-histidine(in) + phosphate => ATP + H2O + L-histidine(out)


name: 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O <=> 4-oxohex-2-enedioate + H(+)


name: a fatty acid + glycerol + H(+) => a 1-acylglycerol + H2O


name: p-PKR dimer phosphorylates CDK1 (Bos taurus)


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Homo sapiens)


name: PIAS1,3 SUMOylates NR5A1 with SUMO2 (Rattus norvegicus)


name: deoxycholate + O2 + reduced [NADPH--hemoprotein reductase] <=> 1beta-hydroxydeoxycholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1D-myo-inositol 1,3-bisphosphate + H2O => 1D-myo-inositol 1-phosphate + phosphate


name: chloride(in) + glycine(in) + 3 Na(+)(in) => chloride(out) + glycine(out) + 3 Na(+)(out)


name: SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Bos taurus)


name: 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Schizosaccharomyces pombe)


name: GNLY binds the bacterial cell surface in the phagosome (Sus scrofa)


name: GP1b-IX-V binds 14-3-3-zeta (Xenopus tropicalis)


name: cholesteryl (7Z)-octadecenoate + CoA => (7Z)-octadecenoyl-CoA + cholesterol


name: ADP + H(+) + L-alanyl-L-glutamate(in) + phosphate => ATP + H2O + L-alanyl-L-glutamate(out)


name: NLRP3 activation by small molecules (Danio rerio)


name: Cross-linking of FCGRIIIA with IgG-coated Ag (Homo sapiens)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Schizosaccharomyces pombe)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Sus scrofa)


name: 2 Na(+)(in) + tauro-beta-muricholate(in) => 2 Na(+)(out) + tauro-beta-muricholate(out)


name: ATP + benzoate + H(+) + NADPH => AMP + benzaldehyde + diphosphate + NADP(+)


name: Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Mus musculus)


name: PPA2A dephosphorylates SPRY2 (Mus musculus)


name: D-glucose(out) + N(pros)-phospho-L-histidyl-[protein] => D-glucose 6-phosphate(in) + L-histidyl-[protein]


name: (S)-ureidoglycolate + urea => allantoate + H2O


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Dictyostelium discoideum)


name: RAS:GTP binds RAL GDS proteins (Mus musculus)


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Sus scrofa)


name: 3 a menaquinone + protoporphyrinogen IX => 3 a menaquinol + protoporphyrin IX


name: H(+) + S-methyl-5'-thioadenosine + thermospermine => S-adenosyl 3-(methylsulfanyl)propylamine + spermidine


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Homo sapiens)


name: Lactoferrin scavenges iron ions (Gallus gallus)


name: (9Z,12Z)-octadecadienoyl-CoA + O2 + reduced [NADPH--hemoprotein reductase] <=> (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (+)-corvol ether A + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: 3-oxosphinganine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoyl-3-oxosphinganine


name: IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Canis familiaris)


name: ATP + CoA + heptanoate => AMP + diphosphate + heptanoyl-CoA


name: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH


name: SPHK1 phosphorylates sphingosine in response to E2 stimulation (Bos taurus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Caenorhabditis elegans)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Canis familiaris)


name: HDACs deacetylate p-STAT3 dimers (Sus scrofa)


name: kainate receptor binds glutamate (Sus scrofa)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Drosophila melanogaster)


name: 10-hydroxy-(11S,12S)-epoxy- (5Z,8Z,14Z)-eicosatrienoate + H2O = (10,11S,12R)-trihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: 15alpha-stemmadenine intermediate I + NADPH => 15alpha-stemmadenine intermediate II + NADP(+)


name: transforming growth factor beta receptor activity, type III


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Rattus norvegicus)


name: Autocatalytic activation of proMMP2 (Danio rerio)


name: 5alpha-cholest-7-en-3-one + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => (25S)-Delta7-dafachronate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Canis familiaris)


name: CO2 + deoxyviolacein + 2 H2O + NADP(+) => 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate


name: (R)-carnitine + NH4(+) => (R)-carnitinamide + H2O


name: adenosine(4) in tRNA(His) + S-adenosyl-L-methionine => 2'-O-methyladenosine(4) in tRNA(His) + H(+) + S-adenosyl-L-homocysteine


name: DECR2 reduces LCtE-CoA to t3enoyl-CoA (Danio rerio)


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Bos taurus)


name: (R)-1-aminopropan-2-ol + NAD(+) => aminoacetone + H(+) + NADH


name: (S)-mandelate + A <=> AH2 + phenylglyoxylate


name: ATP binds G-protein beta associated TRiC/CCT (Gallus gallus)


name: beta-cyclopiazonate + diphosphate => cyclo-acetoacetyl-L-tryptophan + dimethylallyl diphosphate


name: MAF1 translocates to the nucleus (Danio rerio)


name: Aquaporins passively transport water out of cells (Caenorhabditis elegans)


name: Formation of PRC2-EZH2 complex (Sus scrofa)


name: RAB5 and GAPVD1 bind AP-2 (Caenorhabditis elegans)


name: CO2 + S-adenosyl 3-(methylsulfanyl)propylamine => H(+) + S-adenosyl-L-methionine


name: ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels


name: 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH => 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Danio rerio)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> diphosphate + stellata-2,6,19-triene


name: 2-oxobutanoate + CO2 + NADH => (2R,3S)-3-methylmalate + NAD(+)


name: acetate + diphosphate => acetyl phosphate + phosphate


name: MMP14:TIMP2 binds proMMP2 (Canis familiaris)


name: 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate => CO2 + deoxyviolacein + 2 H2O + NAD(+)


name: D-galactose + phosphate => alpha-D-galactose 1-phosphate + H2O


name: isoxazolin-5-one + O-acetyl-L-serine <=> 3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate + H(+)


name: L-erythrulose 1-phosphate => D-erythrulose 1-phosphate


name: Translocation of p-IRF7:p-IRF7 to nucleus (Gallus gallus)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Schizosaccharomyces pombe)


name: (2E)-geranial + H(+) + NADPH => (2E)-geraniol + NADP(+)


name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Rattus norvegicus)


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Homo sapiens)


name: H(+) + H2O + N-benzyloxycarbonylglycine <=> benzyl alcohol + CO2 + glycine


name: a ganglioside GA2 + H2O <=> a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-acetyl-beta-D-galactosamine


name: 1-hydroxypentan-2-one + H(+) + NADH + NH4(+) => 2-aminopentan-1-ol + H2O + NAD(+)


name: formaldehyde + mycothiol <=> S-(hydroxymethyl)mycothiol


name: glycerol + NADP(+) <=> H(+) + L-glyceraldehyde + NADPH


name: TYRP1 oxidises DHICA to IQCA (Homo sapiens)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Sus scrofa)


name: Abortive initiation after formation of the first phosphodiester bond (Sus scrofa)


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + 5 H(+) + 3 O2 + 6 reduced [adrenodoxin] = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + 4 H2O + 6 oxidized [adrenodoxin]


name: ATP + oxaloacetate <=> ADP + CO2 + phosphoenolpyruvate


name: eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Sus scrofa)


name: H2O + L-aspartate + NAD(+) <=> H(+) + NADH + NH4(+) + oxaloacetate


name: DNA ligase I ligates single stranded nick in double stranded DNA (Rattus norvegicus)


name: SHC1 bound to IL2 receptor is phosphorylated (Sus scrofa)


name: adenine + alpha-D-ribose 1-phosphate => adenosine + phosphate


name: 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one (Drosophila melanogaster)


name: 2-hydroxybutanoate + NADP(+) = 2-oxobutanoate + H(+) + NADPH


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Canis familiaris)


name: NEDD4L ubiquitinates SMAD2/3 (Drosophila melanogaster)


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Mus musculus)


name: RAS proteins are depalmitoylated (Canis familiaris)


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Canis familiaris)


name: 2-methylbutanal + H(+) + NADPH + NH4(+) => 2-methylbutanamine + H2O + NADP(+)


name: CHPF,CHSY3 transfer GalNAc to chondroitin (Sus scrofa)


name: griseophenone C + S-adenosyl-L-homocysteine => griseophenone D + S-adenosyl-L-methionine


name: CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds STAT1,3,5 (Homo sapiens)


name: D-iditol + NAD(+) = H(+) + keto-D-sorbose + NADH


name: Formation of eIF2:GDP:eIF2B intermediate (Saccharomyces cerevisiae)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine


name: dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: RAS proteins are depalmitoylated (Gallus gallus)


name: XDH dehydrogenates hypoxanthine to form xanthine (Rattus norvegicus)


name: 18-oxo-resolvin E1 + H(+) + NADH => NAD(+) + resolvin E1


name: C3PO hydrolyzes cleaved passenger strand (Schizosaccharomyces pombe)


name: MRN complex binds DNA double strand breaks (Mus musculus)


name: RBX1:CUL3 dissociates from forming autophagosome (Drosophila melanogaster)


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: PP2A methylation by LCMT1 (Caenorhabditis elegans)


name: (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Rattus norvegicus)


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Saccharomyces cerevisiae)


name: (2E)-geranyl diphosphate <=> (Z)-beta-ocimene + diphosphate


name: GLI2,3 are degraded by the proteasome (Caenorhabditis elegans)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: CoA + scopoletin => (E)-6-hydroxyferuloyl-CoA


name: SALM1 binds NMDA receptor (Canis familiaris)


name: acetyl-CoA + gentamicin C1a = CoA + H(+) + N(2')-acetylgentamicin C1a


name: The addition of GalNAc to the terminal glucuronate residue forms chondroitin (Xenopus tropicalis)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Bos taurus)


name: Association of procollagen type IX (Canis familiaris)


name: MSH2:MSH6 exchanges ADP for ATP (Homo sapiens)


name: PTGIR binds PTGIR agonists (Canis familiaris)


name: Phosphorylation of JAK2 (Rattus norvegicus)


name: H(+) + N,N-dihydroxy-L-hexahomomethionine => (E)-9-(methylsulfanyl)nonanal oxime + CO2 + H2O


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Bos taurus)


name: 3'-phosphoadenylyl sulfate + chenodeoxycholate = adenosine 3',5'-bisphosphate + chenodeoxycholate 7-sulfate + H(+)


name: VMAT1/2 can mediate the transport of biogenic amines (Rattus norvegicus)


name: H2O + N-acetyl-D-galactosamino-1,5-lactone => H(+) + N-acetyl-D-galactosaminate


name: Formation of the MLL1 complex (Sus scrofa)


name: SHP2 binds to the active receptor (Bos taurus)


name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen (Canis familiaris)


name: CoA + myricetin 3-O-[(6-O-(E)-caffeoyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] => (E)-caffeoyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside]


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Danio rerio)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate


name: chloride(in) + L-isoleucine(in) + 2 Na(+)(in) => chloride(out) + L-isoleucine(out) + 2 Na(+)(out)


name: Activation of RAC1 (Caenorhabditis elegans)


name: DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Mus musculus)


name: Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Rattus norvegicus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Gallus gallus)


name: NPAS4 binds ARNTL (BMAL1) (Mus musculus)


name: Formation of NR-NCOR Corepressor Complex (Caenorhabditis elegans)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O <=> H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: aniline + N,N-dimethyl-1,4-phenylenediamine + 2 NADP(+) <=> 4-(dimethylamino)azobenzene + 2 H(+) + 2 NADPH


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Bos taurus)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Canis familiaris)


name: p-T,Y MAPKs dimerize (Schizosaccharomyces pombe)


name: p-AKT2 phosphorylates Myosin 5A (Homo sapiens)


name: Type I Na+-coupled phosphate co-transport (Mus musculus)


name: Association of procollagen type XXII (Canis familiaris)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Canis familiaris)


name: cephalosporin C + H2O = acetate + deacetylcephalosporin C + H(+)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Drosophila melanogaster)


name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Mus musculus)


name: Liberation of CI from SU(FU) repression (Drosophila melanogaster)


name: VTN binds Plasminogen activator inhibitor- 1 (Canis familiaris)


name: SLC22A1 transports Cipro into hepatic cell (Caenorhabditis elegans)


name: (+)-premalbrancheamide + chloride + FAD + 2 H(+) => (+)-isomalbrancheamide B + FADH2


name: (4R)-ipsdienol + NAD(+) <=> H(+) + ipsdienone + NADH


name: SRD5A3 dehydrogenates TEST to DHTEST (Drosophila melanogaster)


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Canis familiaris)


name: Phosphorylated AKT1S1:mTORC1 binds YWHAB (Sus scrofa)


name: Keratin type I binds keratin type II (Danio rerio)


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Dictyostelium discoideum)


name: 12alpha-hydroxy-3-oxochola-4-en-24-oate + H(+) + NADH => 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NAD(+)


name: Anti-MET small tyrosine kinase inhibitors bind MET (Homo sapiens)


name: glyoxal + GTP => N(2)-(1-hydroxy-2-oxoethyl)-GTP


name: Activation of MT-MMPs by FURIN (Rattus norvegicus)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+)


name: Furin cleaves pro-prothrombin to prothrombin (Xenopus tropicalis)


name: Activation of CHEK1 at resected DNA DSBs (Canis familiaris)


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Sus scrofa)


name: ATP + L-glutamate + spermine <=> ADP + gamma-L-glutamylspermine + H(+) + phosphate


name: Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA (Drosophila melanogaster)


name: Expression of IL18, ALOX5 (Homo sapiens)


name: Ubiquitinated TP53 translocates to the cytosol (Xenopus tropicalis)


name: 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+) => L-dopa + O2


name: Interaction of Tie2 and Ang4 (Sus scrofa)


name: COX15 transforms heme O to heme A (Caenorhabditis elegans)


name: PDE3A hydrolyses cAMP to AMP (Mus musculus)


name: GDP-alpha-D-glucose + phosphate <=> alpha-D-glucose 1-phosphate + GDP + H(+)


name: 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: CDC42 GEFs activate CDC42 (Rattus norvegicus)


name: AKT can phosphorylate NR4A1 (NUR77) (Danio rerio)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate


name: [thioredoxin]-disulfide + dGDP + H2O => [thioredoxin]-dithiol + GDP


name: Trimerization of cytosolic HSF1 (Saccharomyces cerevisiae)


name: (6S)-5,6,7,8-tetrahydropteroate + NAD(+) => 7,8-dihydropteroate + H(+) + NADH


name: 9-octadecanoyloxy-octadecanoate + H2O <=> 9-hydroxy-octadecanoate + H(+) + octadecanoate


name: acetyl-CoA + H2O => adenosine 3',5'-bisphosphate + 2 H(+) + S-acetyl-4'-phosphopantetheine


name: Activated TrkA receptor internalizes to endosomes (Bos taurus)


name: acetyl-CoA + N-terminal L-methionyl-L-lysyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein]


name: diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate


name: SIRT1,SIRT3 deacetylate FOXO3 (Caenorhabditis elegans)


name: 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + dimethylallyl diphosphate => 2,4,7,9-tetrahydroxy-6-methyl-8-(2-methylbut-3-en-2-yl)-1-oxo-1H-phenalen-3-ol + diphosphate


name: N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine = N-acyl-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoate (4E)-octadecasphin-4-enine


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Bos taurus)


name: H2O + pentanoate ester <=> an aliphatic alcohol + H(+) + pentanoate


name: glutamate uptake by astrocytes (Homo sapiens)


name: IGFBP3 binds TMEM219 (Rattus norvegicus)


name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression (Homo sapiens)


name: FZ and VANG bind to STAN homodimer (Drosophila melanogaster)


name: ent-copalyl diphosphate => diphosphate + ent-isokaurene


name: Liganded-ALK dimer binds type I ALK-binding TKIs (Bos taurus)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Mus musculus)


name: Autocatalytic phosphorylation of FGFR1c (Mus musculus)


name: YAP1 binds TEAD2 (Caenorhabditis elegans)


name: ATP + CoA + hexacosanoate <=> AMP + diphosphate + hexacosanoyl-CoA


name: DDR2 binds collagen type I, II, III, V, X fibrils (Gallus gallus)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Canis familiaris)


name: Phosphorylation of GAB2 by SFKs (Bos taurus)


name: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 2-hydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: LC3:ATG7 dimer binds ATG3 (Xenopus tropicalis)


name: Acitretin binds to RAR:RXR (Drosophila melanogaster)


name: chrodrimanin C + H(+) + NADPH + O2 => chrodrimanin H + H2O + NADP(+)


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Xenopus tropicalis)


name: 8-oxo-dGDP + H2O => 8-oxo-dGMP + H(+) + phosphate


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Canis familiaris)


name: an acyl-CoA + H(+) + malonyl-CoA => a 3-oxoacyl-CoA + CO2 + CoA


name: beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O <=> chenodeoxycholate + D-glucose


name: NUDT16 hydrolyses IDP to IMP (Canis familiaris)


name: Association of LBP with LPS (Mus musculus)


name: Dopa is oxidized to dopaquinone by TYR (Sus scrofa)


name: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO2


name: (indol-3-yl)acetate + 2 H(+) + NADH => H2O + indole-3-acetaldehyde + NAD(+)


name: 19-(4-hydroxyphenyl)nonadecanoate + ATP + H(+) => 19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + diphosphate


name: FN3K phosphorylates ketosamines (Xenopus tropicalis)