name: Interaction of particulate antigens with dendritic cell receptors (Bos taurus)


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Sus scrofa)


name: Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)


name: 2-oxoglutarate + glyoxylate + H(+) => 2-hydroxy-3-oxoadipate + CO2


name: PTK2 binds activated MET (Canis familiaris)


name: CoA + O-methyl anthranilate => anthraniloyl-CoA + methanol


name: 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + AH2 + O2 <=> 3-demethylubiquinol-8 + A + H2O


name: 4,5,8-trihydroxycasbene + 2 NAD(+) <=> 2 H(+) + jolkinol C + 2 NADH


name: a ganglioside GM1 + H2O <=> a ganglioside GA1 + N-acetylneuraminate


name: GBF1 recruits ARF:GDP to the ERGIC (Canis familiaris)


name: GSDME (1-270) binds cardiolipin (Canis familiaris)


name: H2O + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] => N(alpha)-acetyl-L-methionine + N-terminal L-glutamyl-[protein]


name: dihydroxyacetone + H(+) + NADH => glycerol + NAD(+)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Drosophila melanogaster)


name: Association of INK4 family proteins with CDK4/6 (Sus scrofa)


name: MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Canis familiaris)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Ascorbate can reduce the BH3 radical back to BH4 (Homo sapiens)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Caenorhabditis elegans)


name: SUMOylation of PIAS4 with SUMO1 (Mus musculus)


name: DAG stimulates protein kinase C-delta (Schizosaccharomyces pombe)


name: Association of beta-catenin with the destruction complex (Caenorhabditis elegans)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Canis familiaris)


name: (2E,6E)-farnesoate + 2 H(+) + NADH => (2E,6E)-farnesal + H2O + NAD(+)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + hexadecanoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-hexadecanoyl-sn-glycerol + CoA


name: H(+) + NADH + phenylglyoxylate => (R)-mandelate + NAD(+)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + FAD + H(+) <=> (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + FADH2


name: (E)-sinapate + ATP + CoA <=> (E)-sinapoyl-CoA + AMP + diphosphate


name: p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Xenopus tropicalis)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Rattus norvegicus)


name: Hh-Np traffics to the plasma membrane (Rattus norvegicus)


name: H(+) + H2O + ladanein + oxidized [NADPH--hemoprotein reductase] => apigenin 4',7-dimethyl ether + O2 + reduced [NADPH--hemoprotein reductase]


name: cysteine-type endopeptidase regulator activity involved in apoptotic process


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)


name: SUMOylation of Histone H4 with SUMO1 (Homo sapiens)


name: HIF-alpha translocates from cytosol to nucleus (Mus musculus)


name: abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase] = abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-isoleucine + tuberonate => H2O + L-isoleucine-(+)-12-hydroxy-7-isojasmonate


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Danio rerio)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)


name: Autophagosome maturation (Plasmodium falciparum)


name: Fibrillin-1 binds latent TGF-beta (Mus musculus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 <=> 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O


name: (2E,4Z)-decadienoyl-CoA + H(+) + NADPH => (2E)-decenoyl-CoA + NADP(+)


name: ADP + H(+) + validone 7-phosphate => ATP + validone


name: 2-oxoglutarate + L-arginyl-[ribosomal protein eS6] + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein eS6] + CO2 + succinate


name: 3-hydroxytetradecanoyl-CoA + 2 H(+) + 2 malonyl-CoA => 4-hydroxy-6-(2-hydroxytridecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: 7-dehydrocholesterol + hnu <=> previtamin D3


name: NSF ATPase activity dissociates cis-SNARE at the ER (Gallus gallus)


name: H2O + N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein] <=> N(6)-(D-erythrulosyl)-L-lysyl-[protein] + phosphate


name: DENND4s exchange GTP for GDP on RAB10 (Homo sapiens)


name: LRP1:Hemopexin:heme is endocytosed (Homo sapiens)


name: ATP(in) + H2O(in) + Zn(2+)(out) => ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in)


name: [pyruvate, water dikinase] + ADP <=> [pyruvate, water dikinase]-phosphate + AMP + H(+)


name: AXIN is phosphorylated in the destruction complex (Homo sapiens)


name: NRXNs bind CASK:Protein 4.1 (Danio rerio)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + testosterone => 17beta-estradiol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Caenorhabditis elegans)


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Rattus norvegicus)


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Xenopus tropicalis)


name: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity


name: Benzene is hydroxylated to phenol (Sus scrofa)


name: (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA + H(+) + NADPH = (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADP(+)


name: MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)


name: acetate + deacetylcephalosporin C + H(+) => cephalosporin C + H2O


name: a 2-acyl-sn-glycerol 3-phosphate + choline + H(+) => a 2-acyl-sn-glycero-3-phosphocholine + H2O


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Sus scrofa)


name: 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] + pulcherriminic acid => cyclo(L-leucyl-L-leucyl) + 4 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin]


name: Dissociation of the COP1-p53 complex (Rattus norvegicus)


name: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor


name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 (Sus scrofa)


name: 3-oxoisoapionate 4-phosphate + H2O => (2R)-3-phosphoglycerate + glycolate + H(+)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Mus musculus)


name: (2S)-2-hydroxy-2,4-dimethylpentanenitrile => 4-methylpentan-2-one + hydrogen cyanide


name: phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex (Homo sapiens)


name: H(+) + pyruvate + sulfite => (2R)-3-sulfolactate


name: 2-oxoglutarate + 3-methylnonanoyl-CoA + O2 => 2-hydroxy-3-methylnonanoyl-CoA + CO2 + succinate


name: CYB5A:heme reduces Asc.- to AscH- (Caenorhabditis elegans)


name: RBKS phosphorylates ribose to R5P (Saccharomyces cerevisiae)


name: ATP + CoA + hexadecanoate <=> AMP + diphosphate + hexadecanoyl-CoA


name: chloride(out) + D-alanine(out) + 2 Na(+)(out) <=> chloride(in) + D-alanine(in) + 2 Na(+)(in)


name: a quinol + D-glucono-1,5-lactone => a quinone + D-glucose


name: AKAP8L binds MLL2 complex (Rattus norvegicus)


name: futalosine + H2O => dehypoxanthine futalosine + hypoxanthine


name: 18-hydroxy-(9S,10R)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9S,10R)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: NRXNs bind CASK:Protein 4.1 (Sus scrofa)


name: ATAT acetylates microtubules (Bos taurus)


name: Activated TP receptor binds G-protein  G13 (Sus scrofa)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Plasmodium falciparum)


name: aklavinone + NADP(+) = aklaviketone + 2 H(+) + NADPH


name: an (E)-omega-(methylsulfanyl)-alkanal oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> a (1E)-1-aci-nitro-omega-(methylsulfanyl)alkane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: BCL gene expression downstream of ESR1 (Homo sapiens)


name: RANKL,sRANKL trimer binds RANK (Bos taurus)


name: ATR activation at DNA DSBs (Canis familiaris)


name: Phosphorylation of CTLA-4 (Homo sapiens)


name: an N-acylsphing-4-enine + dTDP-alpha-D-glucose => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + dTDP + H(+)


name: IL19 binds IL20RA:JAK1:IL20RB (Mus musculus)


name: ADP(in) + dATP(out) => ADP(out) + dATP(in)


name: GDP(in) + UTP(out) => GDP(out) + UTP(in)


name: YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Caenorhabditis elegans)


name: RANBP2 SUMOylates PML with SUMO2 (Bos taurus)


name: (11R)-dihydroartemisinic aldehyde + H2O + NADP(+) = (11R)-dihydroartemisinate + 2 H(+) + NADPH


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Drosophila melanogaster)


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Rattus norvegicus)


name: H(+) + quercetin 3-O-beta-D-glucoside + UDP => quercetin + UDP-alpha-D-glucose


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Mus musculus)


name: Mis18 complex binds the centromere (Sus scrofa)


name: CYP3A4,5 oxidise AFB1 to AFXBO (Danio rerio)


name: 1D-chiro-inositol(in) + 2 Na(+)(in) => 1D-chiro-inositol(out) + 2 Na(+)(out)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Plasmodium falciparum)


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Bos taurus)


name: 2 Na(+)(in) + thymidine(in) => 2 Na(+)(out) + thymidine(out)


name: PTK6 phosphorylates ARAP1 (Rattus norvegicus)


name: TRAF1 binds TRAF2 within TNFR1 signaling complex (Xenopus tropicalis)


name: CHMP7 binds LEMD2 (Saccharomyces cerevisiae)


name: NFkB complex translocates from the cytosol to the nucleus (Homo sapiens)


name: ent-isokaurene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = ent-isokaurene-2beta,3beta-diol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: inositol hexakisphosphate kinase activity


name: cAMP hydrolysis by Cam-PDE 1 (Bos taurus)


name: Transphosphorylation of pLIMK1 (Canis familiaris)


name: (S)-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = (13S,14R)-1,13-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p-T182 MAPKAPK5 binds DNAJB1 (Homo sapiens)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Caenorhabditis elegans)


name: CTP(in) + GDP(out) => CTP(out) + GDP(in)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Rattus norvegicus)


name: 2-MAG is transacylated to DAG by PNPLA2/3 (Sus scrofa)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Gallus gallus)


name: PLOD3 binds Lysyl hydroxylated collagen propeptides (Xenopus tropicalis)


name: Exocytosis of specific granule membrane proteins (Bos taurus)


name: NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP (Xenopus tropicalis)


name: HLA-G specific inhibitory MHC class Ib receptor activity


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Canis familiaris)


name: 3beta-hydroxy-5-androstene-7,17-dione + H(+) + NADPH => 3beta,7beta-dihydroxyandrost-5-en-17-one + NADP(+)


name: (R)-glycerate + CO2 + NAD(+) <=> 2-hydroxy-3-oxosuccinate + 2 H(+) + NADH


name: (2E,13Z)-eicosadienoyl-CoA + H(+) + NADPH => (13Z)-eicosenoyl-CoA + NADP(+)


name: Association of procollagen type XIV (Homo sapiens)


name: acetyl-CoA + N-terminal L-methionyl-L-isoleucyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein]


name: factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Xenopus tropicalis)


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Xenopus tropicalis)


name: PAK1 phosphorylates LIMK1 (Gallus gallus)


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Rattus norvegicus)


name: diphosphate + sesquisabinene A => (2E,6E)-farnesyl diphosphate


name: Association of CCT/TriC with sphingosine kinase 1 (Sus scrofa)


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: Reduction of presqualene diphosphate to form squalene (Xenopus tropicalis)


name: RAC1:GTP binds NOX3 complex (Xenopus tropicalis)


name: ATP + dodecanoate + H(+) <=> diphosphate + dodecanoyl-AMP


name: 3-(2-hydroxyphenyl)propanoate + H(+) => 3,4-dihydrocoumarin + H2O


name: decanoate ester + H2O = an aliphatic alcohol + decanoate + H(+)


name: ATP + glutathione + glutathionylspermidine => ADP + H(+) + phosphate + trypanothione


name: 9-(9Z-hexadecenoyloxy)-octadecanoate + di-(9Z)-hexadecenoylglycerol => 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate


name: ULK complex translocates to the ER (Bos taurus)


name: H(+) + N-tetracosanoyl-sphing-4-enine + phosphocholine => H2O + N-(tetracosanoyl)-sphing-4-enine-1-phosphocholine


name: NFE2L2 and MAFG bind the SQSTM1 gene (Homo sapiens)


name: D-xylose(out) + H(+)(out) => D-xylose(in) + H(+)(in)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Saccharomyces cerevisiae)


name: PTK6 phosphorylates ARHGAP35 (Mus musculus)


name: ITCH ubiquitinates DTX (Rattus norvegicus)


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Bos taurus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Gallus gallus)


name: nicotinate + S-adenosyl-L-methionine <=> N-methylnicotinate + S-adenosyl-L-homocysteine


name: G protein-coupled photoreceptor activity


name: Release of E3 from polyubiquitinated substrate (Homo sapiens)


name: KHK dimer phosphorylates Fru to Fru 1-P (Homo sapiens)


name: CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)


name: MYO9B inactivates RHOA (Rattus norvegicus)


name: SLC16A10-mediated uptake of aromatic amino acids (Dictyostelium discoideum)


name: (+)-pinoresinol + H2O + 2 oxidized [azurin] => (+)-6-hydroxypinoresinol + 2 H(+) + 2 reduced [azurin]


name: NAD(+) + ursodeoxycholate => 7-oxolithocholate + H(+) + NADH


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)


name: dimethylallyl diphosphate + phlorisovalerophenone => 4-prenylphlorisovalerophenone + diphosphate


name: GDP-alpha-D-rhamnose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: SUMOylation of UBE2I with SUMO1 (Sus scrofa)


name: Crk binds to the active PDGF receptor (Mus musculus)


name: acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate (Mycobacterium tuberculosis)


name: H2O + L-tyrosine + O2 = 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: MAPK4,6 translocate to nucleus (Gallus gallus)


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Gallus gallus)


name: 3-hydroxy-6-carboxyhexanoyl-CoA + H(+) => 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O


name: 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine => 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Rattus norvegicus)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Mus musculus)


name: a dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine => N-acetyl-alpha-D-glucosaminyl-diphosphodolichol + UMP


name: asperlicin C + H(+) + NADPH + O2 <=> asperlicin E + H2O + NADP(+)


name: PTK2/SRC-1 phosphorylates BCAR1 (Homo sapiens)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Canis familiaris)


name: CDK2 phosphorylates RBBP8 (Rattus norvegicus)


name: Activation of linoleic acid to linoleoyl-CoA (Plasmodium falciparum)


name: Formation of the 43S pre-initiation complex (Mus musculus)


name: L-pipecolate + NAD(+) => Delta(1)-piperideine-2-carboxylate + H(+) + NADH


name: 4',7-dihydroxy-3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine


name: (E)-4-coumarate + reduced [electron-transfer flavoprotein] => H(+) + oxidized [electron-transfer flavoprotein] + phloretate


name: hydrogen sulfide + NADP(+) + n sulfur = NADPH + (n+1) sulfur


name: desmethyldescarbamoylnovobiocin + dTDP + H(+) => dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Bos taurus)


name: EGFR binds EPS15, EPN1, EPS15L1 (Bos taurus)


name: dopamine + S-adenosyl-L-methionine => 3-methoxytyramine + H(+) + S-adenosyl-L-homocysteine


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Dictyostelium discoideum)


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Sus scrofa)


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Bos taurus)


name: 3'-phosphoadenylyl sulfate + tauro-alpha-muricholate = adenosine 3',5'-bisphosphate + H(+) + tauro-alpha-muricholate 7-sulfate


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Caenorhabditis elegans)


name: IL21 receptor STAT binding (Canis familiaris)


name: Dephosphorylation of PAG by SHP2 (Gallus gallus)


name: alpha-D-glucose 1-phosphate + ATP => ADP + alpha-D-glucose 1,6-bisphosphate + H(+)


name: 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: H2O + hexanal + NAD(+) <=> 2 H(+) + hexanoate + NADH


name: AVPR2 bind desmopressin (Rattus norvegicus)


name: NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)


name: 2-exo-hydroxy-1,8-cineole + NAD(+) <=> 6-oxocineole + H(+) + NADH


name: Basigin binds MCT1, MCT3 and MCT4 (Bos taurus)


name: Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)


name: a short-chain fatty acid + ATP + CoA <=> a short-chain fatty acyl-CoA + AMP + diphosphate


name: a 1-acyl-sn-glycerol + a fatty acid + H(+) => a 1,3-diacyl-sn-glycerol + H2O


name: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + L-2,4-diaminobutanoate = L-aspartate 4-semialdehyde + L-glutamate


name: ADP + gamma-L-glutamyl-L-glutamyl-[tubulin] + H(+) + phosphate => ATP + L-glutamate + L-glutamyl-[tubulin]


name: L-arogenate + oxaloacetate <=> L-aspartate + prephenate


name: 7-chloro-L-tryptophan + O2 => 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2


name: ARSA removes sulfate from PSAP(195-273):Sulfatide (Rattus norvegicus)


name: ABCB1 transports xenobiotics out of the cell (Rattus norvegicus)


name: guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H(+)


name: H(+)(out) + L-leucine(in) => H(+)(in) + L-leucine(out)


name: P2Y10 receptor can bind to LPA (Homo sapiens)


name: Expression of IRX2 during nephron development (Homo sapiens)


name: ATP + xylitol => ADP + H(+) + xylitol 5-phosphate


name: (S)-2-hydroxyglutarate(out) + 3 Na(+)(out) => (S)-2-hydroxyglutarate(in) + 3 Na(+)(in)


name: AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Rattus norvegicus)


name: a long-chain fatty aldehyde + FMNH2 + O2 => a long-chain fatty acid + FMN + 2 H(+) + H2O + hnu


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Sus scrofa)


name: (S)-Malate <=> Fumarate + H2O (Caenorhabditis elegans)


name: diphosphate + ent-manool => ent-copalyl diphosphate + H2O


name: Defective SLC5A1 does not cotransport Glc and Na+ (Homo sapiens)


name: Exocytosis of specific granule lumen proteins (Gallus gallus)


name: CP110 and CEP97 dissociate from the centriole (Bos taurus)


name: (S)-indan-1-ol + NAD(+) => H(+) + indan-1-one + NADH


name: AKAP5 recruits PKC to ROBO2 (Homo sapiens)


name: ERBB4s80 forms a complex with estrogen receptor ESR1 (Sus scrofa)


name: Tetramerization of procollagen VI (Bos taurus)


name: voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization


name: GUCY2C trimer binds GUCA2A,B (Xenopus tropicalis)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Xenopus tropicalis)


name: 5alpha-androstane-3beta,17beta-diol + NADP(+) => 3beta-hydroxy-5alpha-androstan-17-one + H(+) + NADPH


name: acetyl-CoA + streptothricin F => CoA + H(+) + N(beta)-acetylstreptothricin F


name: [deoxyhypusine synthase]-L-lysine + dehydrospermidine => [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine


name: NR1H4 binds DCA, CDCA, LCHA (Drosophila melanogaster)


name: N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate => H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein]


name: H2O + N-acyl-sn-glycero-3-phosphoethanolamine <=> an N-acylethanolamine + H(+) + sn-glycerol 3-phosphate


name: H2O + N'-monoacetylchitobiose-6'-phosphate <=> D-glucosamine + N-acetyl-D-glucosamine 6-phosphate


name: choline + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = betaine aldehyde hydrate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SPRY2 translocates to the plasma membrane (Xenopus tropicalis)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: Activated FGFR3 binds FRS3 (Danio rerio)


name: IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Xenopus tropicalis)


name: H2O + N(6)-dodecanoyl-L-lysyl-[protein] + NAD(+) => 2''-O-dodecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)


name: SCF-beta-TrCP ubiquitinylates IkB (Rattus norvegicus)


name: E2F1 binds the TK1 gene promoter (Homo sapiens)


name: NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix] (Rattus norvegicus)


name: 2-aminoisobutanoate(out) + L-alanine(in) <=> 2-aminoisobutanoate(in) + L-alanine(out)


name: (4E)-hexenoyl-CoA + NADP(+) => (2E,4E)-hexadienoyl-CoA + H(+) + NADPH


name: D-galactose(in) + H(+)(in) <=> D-galactose(out) + H(+)(out)


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Canis familiaris)


name: alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Xenopus tropicalis)


name: CYP3A43 6b-hydroxylates TEST (Rattus norvegicus)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Dictyostelium discoideum)


name: ERBB4 forms heterodimers with EGFR (Xenopus tropicalis)


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Rattus norvegicus)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O


name: PCK2 phosphorylates OA to yield PEP (Sus scrofa)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Bos taurus)


name: GMP + 2 H(+) + 2 phosphate => GTP + 2 H2O


name: PI3 binds the bacterial surface (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ATP + H2O => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ADP + H(+) + phosphate


name: 2-thio-N(6)-dimethylallyladenosine(37) in tRNA + S-adenosyl-L-methionine <=> 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+) => (R)-noradrenaline + L-glutaminyl-[protein]


name: acetyl-CoA + an acyl-CoA <=> a 3-oxoacyl-CoA + CoA


name: p-S54-PDE4B hydrolyses cAMP (Canis familiaris)


name: Activation of HCN channels (Gallus gallus)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-6-sulfoquinovose = a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H(+) + UDP


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Rattus norvegicus)


name: indole-3-ethanol + NAD(+) <=> H(+) + indole-3-acetaldehyde + NADH


name: (3S)-citramalate + succinyl-CoA <=> (3S)-citramalyl-CoA + succinate


name: Collagen type I degradation by MMP14 (Homo sapiens)


name: succinate(in) + sulfate(out) => succinate(out) + sulfate(in)


name: AMP + diphosphate + docosanoyl-CoA => ATP + CoA + docosanoate


name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa (Rattus norvegicus)


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A <=> 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Bos taurus)


name: 3-methylcyclopentanamine + H2O + NADP(+) => 3-methylcyclopentanone + H(+) + NADPH + NH4(+)


name: Cargo Recognition And Sorting (Gallus gallus)


name: a 1,2-diacyl-sn-glycerol + H2O => a 1-acyl-sn-glycerol + a fatty acid + H(+)


name: 2 bilirubin IXalpha + O2 <=> 2 biliverdin IXalpha + 2 H2O


name: Hydrolysis of internal thioester in C4b (Mus musculus)


name: 2xTNFR2 binds TNFA trimer:TNFR2 (Mus musculus)


name: NPC1L1 binds ezetimibe (Saccharomyces cerevisiae)


name: POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 (Sus scrofa)


name: H2O + L-methionine + O2 <=> 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+)


name: U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity


name: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-O-methyladenosine in U2 snRNA + H(+) + S-adenosyl-L-homocysteine


name: CHGA-derived peptide binds the bacterial cell surface (Canis familiaris)


name: CoA + O-pentanoyl-L-seryl-[protein] => L-seryl-[protein] + pentanoyl-CoA


name: gypsogenate + UDP-alpha-D-glucose = gypsogenate 28-beta-D-glucoside + UDP


name: an N-acyl-L-phenylalanine + H2O => a fatty acid + L-phenylalanine


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Xenopus tropicalis)


name: SNAI1,SNAI2 bind the PTEN gene promoter (Homo sapiens)


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(7Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SMURF2 ubiquitinates SMAD2 (Danio rerio)


name: (S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 => 2,4-dichlorophenol + CO2 + pyruvate + succinate


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate


name: a quinol + nitrate <=> a quinone + H2O + nitrite


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Danio rerio)


name: Acireductone is oxidized to MOB (Dictyostelium discoideum)


name: CDK5:p25 phosphorylates PRDX2 (Homo sapiens)


name: (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+) => (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H(+) + NADPH


name: Activation of p38MAPK by DSCAM (Sus scrofa)


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Rattus norvegicus)


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose


name: Peroxynitrite can oxidise BH4 to the BH3 radical (Homo sapiens)


name: (13Z)-docosenoate + NH4(+) => (13Z)-docosenamide + H2O


name: 4-methyl-2-oxopentanoate + CO2 => (2S)-2-isopropyl-3-oxosuccinate + H(+)


name: GTP + H2O <=> 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H(+)


name: CPO transforms COPRO3 to PPGEN9 (Sus scrofa)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: AH2 + neomycin C + S-adenosyl-L-methionine => 5'-deoxyadenosine + A + H(+) + L-methionine + neomycin B


name: 7-O-methylmyricetin + H(+) + S-adenosyl-L-homocysteine => myricetin + S-adenosyl-L-methionine


name: 1,2,3-trihydroxybenzene + O2 => (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Caenorhabditis elegans)


name: 6-deoxotyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + typhasterol


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Mus musculus)


name: TCF:Beta-catenin binds SOX proteins (Canis familiaris)


name: RANBP2 SUMOylates HDAC4 with SUMO2,3 (Gallus gallus)


name: Caspase-mediated cleavage of MST3 (Danio rerio)


name: IMP + NADP(+) + NH4(+) = GMP + 2 H(+) + NADPH


name: 2 a thiol + L-cysteinyl-[sulfatase] + O2 <=> 3-oxo-L-alanyl-[sulfatase] + an organic disulfide + H(+) + H2O + hydrogen sulfide


name: VAV2 is a GEF for Rho/Rac family kinases (Rattus norvegicus)


name: RANBP2 SUMOylates HDAC4 with SUMO2,3 (Mus musculus)


name: 7,8-dihydroneopterin 3'-triphosphate => 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde triphosphate


name: TP53 stimulates BNIP3L expression (Homo sapiens)


name: Nuclear VBC complex ubiquitinylates HIF-alpha (Gallus gallus)


name: ADP + H(+) + Mg(2+)(in) + phosphate => ATP + H2O + Mg(2+)(out)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Canis familiaris)


name: RIPK1 is cleaved by CASP8:FLIP(L) (Sus scrofa)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: Casein kinase II phosphorylates PTEN (Canis familiaris)


name: NUDT16 hydrolyses dIDP to dIMP (Canis familiaris)


name: Phosphorylation of Cdh1 by Cyclin B1:Cdc2 (Bos taurus)


name: acrylate + H(+) + NADH = NAD(+) + propanoate


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Homo sapiens)


name: HRSP12 deaminates 2AA to 2OBUTA (Sus scrofa)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Bos taurus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ATP + CoA => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + AMP + diphosphate


name: a bacteriochlorophyllide d + S-adenosyl-L-methionine <=> a bacteriochlorophyllide c + H(+) + S-adenosyl-L-homocysteine


name: a fatty acyl-[ACP] + H2O => a fatty acid + H(+) + holo-[ACP]


name: 2 (S)-lactate(out) + prostaglandin H2(in) => 2 (S)-lactate(in) + prostaglandin H2(out)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Gallus gallus)


name: Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Gallus gallus)


name: PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Schizosaccharomyces pombe)


name: MAP2Ks and MAPKs bind to the activated RAF complex (Bos taurus)


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Homo sapiens)


name: (S)-dihydroorotate + a ubiquinone <=> a ubiquinol + orotate


name: 3-(all-trans-nonaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> 2-methoxy-6-(all-trans-nonaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: 3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-seryl-[protein] + ATP = 3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phospho-alpha-D-mannosyl)-L-seryl-[protein] + ADP + H(+)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine <=> [(1->4)-N-acetyl-beta-D-glucosaminyl](n+1) + H(+) + UDP


name: GLUT1 tetramer binds 4xATP (Rattus norvegicus)


name: gibberellin A3 + UDP-alpha-D-glucose <=> gibberellin A3 O-beta-D-glucoside + H(+) + UDP


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Gallus gallus)


name: cholesterol + NADP(+) => 7-dehydrocholesterol + H(+) + NADPH


name: crocetin + UDP-alpha-D-glucose <=> beta-D-glucosyl crocetin + UDP


name: (2E)-geranyl diphosphate + 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + H2O + selenophosphate = (2E)-thiogeraniol + 5-methylaminomethyl-2-selenouridine(34) in tRNA + diphosphate + phosphate


name: Ubiquitinated Cdc6 is degraded by the proteasome (Drosophila melanogaster)


name: (E)-caffeoylpyruvate + H2O <=> (E)-caffeate + H(+) + pyruvate


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: UDP-alpha-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Bos taurus)


name: voltage-gated monoatomic cation channel activity


name: (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NAD(+) => 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADH


name: (R)-limonene 1,2-monooxygenase NADH activity


name: SIRT4 transfers ADPRib to GLUD (Danio rerio)


name: Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix (Homo sapiens)


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Mus musculus)


name: 3,4-dichloroaniline + malonyl-CoA => CoA + N-(3,4-dichlorophenyl)malonamate


name: CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine => (R)-4'-phosphopantothenate + CTP + L-cysteine


name: H(+) + N-carbamoyl-D-phenylglycine => D-5-phenylhydantoin + H2O


name: Dephosphorylation of AKT by PP2A (Saccharomyces cerevisiae)


name: choline + H(+) + sn-glycerol 3-phosphate => H2O + sn-glycerol 3-phosphocholine


name: Ligand-independent dimerization of EGFRvIII mutant (Homo sapiens)


name: (1R,2S,4R)-borneol + NAD(+) => (1R,4R)-camphor + H(+) + NADH


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Saccharomyces cerevisiae)


name: 3-(methylsulfanyl)propanoyl-CoA + butan-1-ol => butyl 3-(methylsulfanyl)propanoate + CoA


name: H2O + O2 + tryptamine <=> H2O2 + indole-3-acetaldehyde + NH4(+)


name: ARSC hydrolyzes steroid sulfates (Rattus norvegicus)


name: PRDX1 overoxidizes (Drosophila melanogaster)


name: ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Rattus norvegicus)


name: PG and CDP-DAG are converted to CL by CRLS1 (Caenorhabditis elegans)


name: Dissociation of Cdc20 from APC/C complex (Xenopus tropicalis)


name: 2 3-(4-hydroxyphenyl)pyruvate + H(+) = (2S)-2-(4-hydoxybenzyl)-3-(4-hydroxyphenyl)-2-furonol carboxylate + H2O


name: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Homo sapiens)


name: D-erythrose + phosphate => D-erythrose 4-phosphate + H2O


name: hexadecanoyl-CoA + sphinga-(4E,8Z)-dienine = CoA + H(+) + N-hexadecanoylsphinga-(4E,8Z)-dienine


name: Aquaporin-1 passively transports water into cell (Xenopus tropicalis)


name: ULK1 Translocates to the mitochondria (Saccharomyces cerevisiae)


name: MCM3 binds MCM5 (Drosophila melanogaster)


name: PADI4 deiminates Histones (Rattus norvegicus)


name: L-homocysteine = 2-aminobut-2-enoate + H(+) + hydrogen sulfide


name: acetyl-CoA + L-homoserine <=> CoA + O-acetyl-L-homoserine


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Gallus gallus)


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Sus scrofa)


name: 2-heptyl-3-hydroxy-4(1H)-quinolone + O2 => CO + H(+) + N-octanoylanthranilate


name: CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Caenorhabditis elegans)


name: Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)


name: Inactivation of Myt1 kinase (Rattus norvegicus)


name: Phosphorylation of EGFR by SRC kinase (Homo sapiens)


name: PDCL binds G-protein beta and TRiC/CCT (Sus scrofa)


name: Association of procollagen type XII (Canis familiaris)


name: GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate (Bos taurus)


name: TYRP1 oxidises DHICA to IQCA (Bos taurus)


name: ATP + histamine + L-glutamate => ADP + H(+) + N(alpha)-gamma-L-glutamylhistamine + phosphate


name: Active FLT3 binds to CBL (Canis familiaris)


name: acetate(in) + Na(+)(in) <=> acetate(out) + Na(+)(out)


name: [5-(aminomethyl)furan-3-yl]methyl diphosphate + gamma-L-glutamyltyramine => (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate


name: Elongation Of The Telomeric Chromosome End (Bos taurus)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Mus musculus)


name: dihydromacarpine + H(+) + O2 = H2O2 + macarpine


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Sus scrofa)


name: AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Bos taurus)


name: Proteasomal clevage of exogenous antigen (Danio rerio)


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Rattus norvegicus)


name: Activation of Ca-permeable Kainate receptors (Bos taurus)


name: ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA (Rattus norvegicus)


name: ROCK1,ROCK2 are activated (Mus musculus)


name: (3S)-3-hydroxycyclohexane-1-carbonyl-CoA + NADP(+) => (5S)-5-hydroxycyclohex-1-ene-1-carbonyl-CoA + H(+) + NADPH


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Xenopus tropicalis)


name: H2O + L-cysteinyl-[sulfatase] + S-adenosyl-L-methionine => 3-oxo-L-alanyl-[sulfatase] + 5'-deoxyadenosine + 2 H(+) + hydrogen sulfide + L-methionine


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Caenorhabditis elegans)


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)


name: 2-nitrobutanedioate => fumarate + H(+) + nitrite


name: IL7:IL7R:JAK1 binds IL2RG:JAK3 (Bos taurus)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Canis familiaris)


name: ADD1:ADD2 binds DMTN (Caenorhabditis elegans)


name: The retrograde IFT train dissociates (Mus musculus)


name: 2 Fe(III)-[cytochrome b5] + NADPH => 2 Fe(II)-[cytochrome b5] + H(+) + NADP(+)


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Homo sapiens)


name: 1D-myo-inositol 1,2,6-trisphosphate + H2O <=> 1D-myo-inositol 1,2-bisphosphate + phosphate


name: RasGRP interacts with DAG and Ca2+ (Homo sapiens)


name: Mcm4,6,7 trimer forms and associates with the replication fork (Plasmodium falciparum)


name: (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+) => 1,2-di-(9Z-octadecenoyl)-glycerol + H2O


name: Unwinding of DNA for the nascent HIV-1 transcript: Second Transition (Homo sapiens)


name: 15-oxoprostaglandin F1alpha + H(+) + NADPH => 13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+)


name: Furin cleaves pro-GAS6 to GAS6 (Gallus gallus)


name: p-STAT1 binds p-STAT3 (Dictyostelium discoideum)


name: arginine + H2O => ornithine + urea [ARG2] (Xenopus tropicalis)


name: dihydroprecondylocarpine acetate => (-)-tabersonine + acetate + H(+)


name: 2 3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + 2 O2 = formate + grixazone A + H(+) + 3 H2O


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)


name: Cap-bound mRNA is activated by helicases  (Saccharomyces cerevisiae)


name: Translocation of Ezrin to plasma membrane (Gallus gallus)


name: CBL binds and ubiquitinates phosphorylated Sprouty (Danio rerio)


name: GNRHR binds chemical antagonists (Canis familiaris)


name: cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + diphosphate => 2-hydroxyethylphosphonate + CTP


name: SHC1 bound to IL2 receptor is phosphorylated (Mus musculus)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Schizosaccharomyces pombe)


name: an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+) => a 2-deoxystreptamine antibiotic + acetyl-CoA


name: L-tryptophan + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-tryptophan + oxidized [NADPH--hemoprotein reductase]


name: (E)-caffeoyl-CoA + D-threo-isocitrate => 2-[(E)-caffeoyl]-D-threo-isocitrate(3-) + CoA


name: xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity


name: (2R)-3-phosphoglycerate + [phosphate](n+1) => (2R)-3-phospho-glyceroyl phosphate + [phosphate](n)


name: Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it (Xenopus tropicalis)


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Schizosaccharomyces pombe)


name: D-alanine + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate => H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanine


name: Inactivation of PLC beta (Gallus gallus)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Rattus norvegicus)


name: ATP + L-threonyl-[Fas-activated protein] => ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein]


name: beta-L-fucose 1-phosphate + GTP + H(+) = diphosphate + GDP-beta-L-fucose


name: L-cysteine + O2 <=> 3-sulfino-L-alanine + H(+)


name: CYTH proteins stimulate ARF1 GTPase activity (Xenopus tropicalis)


name: Caspase 3-mediated cleavage of PKC delta (Canis familiaris)


name: D-ribulose 5-phosphate <=> ribose 5-phosphate (Drosophila melanogaster)


name: Apelin receptor binds to apelin (Sus scrofa)


name: TRADD:TRAF2:RIP1 complex dissociates from the TNF-α:TNF-R1 complex. (Mus musculus)


name: H2O + O-(ADP-D-ribosyl)-L-seryl-[protein] <=> ADP-D-ribose + L-seryl-[protein]


name: naringenin chalcone 4'-O-glucosyltransferase activity


name: H(+) + H2O + O-carbamoyl-L-serine = CO2 + 2 NH4(+) + pyruvate


name: 2 a 3-acyl-sn-glycero-1-phospho-(1'-sn-glycerol) = a 3-acyl-sn-glycero-1-phospho-(3'-acyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Rattus norvegicus)


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Drosophila melanogaster)


name: carcinine + H2O => beta-alanine + histamine


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Mus musculus)


name: D-alanine + N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl => H2O + N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Mus musculus)


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Bos taurus)


name: albendazole + H(+) + NADPH + O2 <=> albendazole S-oxide + H2O + NADP(+)


name: Prokineticin receptors bind prokineticin (Canis familiaris)


name: Conformational changes in gp120 exposes gp41 (Homo sapiens)


name: H2O + N(1),N(12)-diacetylspermine + O2 <=> 3-acetamidopropanal + H2O2 + N(1)-acetylspermidine


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Sus scrofa)


name: D-galactose + H(+) + NADPH => galactitol + NADP(+)


name: SULTs transfer (SO4)2- group to 27HCHOL (Drosophila melanogaster)


name: 3-hydroxydodecanoate + H(+) + NADPH + O2 = 3,12-dihydroxydodecanoate + H2O + NADP(+)


name: a ganglioside GM2 + H2O => a ganglioside GA2 + N-acetylneuraminate


name: cis-zeatin UDP glycosyltransferase activity


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Danio rerio)


name: hexadecanoyl-CoA + tetradecan-1-ol = CoA + tetradecanyl hexadecanoate


name: EBI3 gene transcription and translation (Homo sapiens)


name: a (2S)-2-hydroxycarboxylate + a halide anion + H(+) => an (S)-2-haloacid + H2O


name: MTA is cleaved and phosphorylated (Rattus norvegicus)


name: CI75 transports from the cytosol to the nucleus (Drosophila melanogaster)


name: an N-acylsphing-4-enine + CDP-choline => a sphingomyelin + CMP + H(+)


name: Autocatalytic activation of MMP7 (Gallus gallus)


name: RPE dimers isomerise RU5P to XY5P (Bos taurus)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Bos taurus)


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Dictyostelium discoideum)


name: Activation of Ca-permeable Kainate receptors (Caenorhabditis elegans)


name: 3'-phosphoadenylyl sulfate + alpha,alpha-trehalose => 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+)


name: RP2 activates the GTPase activity of ARL3 (Mus musculus)


name: 2xPPCS ligates PPanK with Cys (Mus musculus)


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine <=> 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine


name: factor XII -> factor XIIa (Homo sapiens)


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Rattus norvegicus)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Schizosaccharomyces pombe)


name: Cd(2+)(out) + 2 hydrogencarbonate(out) => Cd(2+)(in) + 2 hydrogencarbonate(in)


name: Translocation and activation of PKC alpha in response to WNT signaling (Homo sapiens)


name: 3-methyl-2-oxobutanoate + L-glutamate => 2-oxoglutarate + L-valine


name: Collagen type XV restin release (Sus scrofa)


name: (R)-2,3-diaminopropanoate + H(+) + H2O = 2 NH4(+) + pyruvate


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Canis familiaris)


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Homo sapiens)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Drosophila melanogaster)


name: TP receptor can bind thromboxane (Bos taurus)


name: 2-oxoglutarate + O2 + thebaine = CO2 + formaldehyde + neopinone + succinate


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Sus scrofa)


name: AFG3L2:SPG7 binds SMDT1 (EMRE) (Mus musculus)


name: FZD recruits trimeric G-proteins (Homo sapiens)


name: GAR + 10-Formyl-THF => FGAR + THF (Bos taurus)


name: betaenone C + H(+) + NADPH + O2 <=> H2O + NADP(+) + stemphyloxin I


name: CHRM1,3,5 bind acetylcholine (Drosophila melanogaster)


name: Dimerization of LIMK1 by Hsp90 (Dictyostelium discoideum)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP => delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-alpha-D-glucose


name: ATG3 transfers LC3 from ATG7 to ATG3 (Gallus gallus)


name: 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH => 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+)


name: estrone 3-sulfate(out) + propanoate(in) = estrone 3-sulfate(in) + propanoate(out)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O => (9Z)-octadecenoate + 1,3-dihexadecanoylglycerol + H(+)


name: dihydrogeodin + 2 FAD + H(+) + 4 H2O => 2 chloride + 2 FADH2 + 2 O2 + sulochrin


name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: H(+)(in) + sucrose(out) => H(+)(out) + sucrose(in)


name: phenylsuccinate + succinyl-CoA => 3-phenylsuccinyl-CoA + succinate


name: a (R)-2-hydroxy fatty acid + O2 = a fatty acid + CO2 + H2O


name: 2-glutathionyl-2-methylbut-3-en-1-ol = (3R)-3,4-epoxy-3-methylbut-1-ene + glutathione


name: H2O + L-threonyl-L-serine => L-serine + L-threonine


name: chloride(out) + L-cysteine(out) + 2 Na(+)(out) = chloride(in) + L-cysteine(in) + 2 Na(+)(in)


name: 2 5'-hydroxy-diadenylate 2',3'-cylic phosphate => cyclic tetraadenylate


name: 1-chloro-2-nitrobenzene + NADH + O2 <=> 3-chlorocatechol + NAD(+) + nitrite


name: 3 H(+) + hexadecanoyl-CoA + 3 malonyl-CoA <=> 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: 2 N(omega)-hydroxy-L-arginine + 2 O2 + reduced [flavodoxin] <=> 3 H(+) + 2 H2O + 2 L-citrulline + 2 nitric oxide + oxidized [flavodoxin]


name: AJUBA binds centrosome-associated AURKA (Bos taurus)


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Bos taurus)


name: (6S)-5,6,7,8-tetrahydrofolate(out) + ATP + H2O => (6S)-5,6,7,8-tetrahydrofolate(in) + ADP + H(+) + phosphate


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Xenopus tropicalis)


name: a 2-deoxy-alpha-D-glucoside + H2O <=> 2-deoxy-D-glucose + an alcohol


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Danio rerio)


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NAD(+) <=> (2S)-2-acetolactate + H(+) + NADH


name: A + O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine => AH2 + alstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: D-mannitol + NADP(+) => D-fructose + H(+) + NADPH


name: cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity


name: Beta-defensins bind microbial membranes causing disruption (Bos taurus)


name: 1D-myo-inositol 4-phosphate + H2O => myo-inositol + phosphate


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Mus musculus)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Caenorhabditis elegans)


name: (2E)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in) => (E)-hexadec-2-enoate(out) + ATP(in) + CoA(in) + H(+)(out)


name: Defective PMM2 does not isomerise Man6P to Man1P (Homo sapiens)


name: Interaction of GPVI and FceRI gamma (Xenopus tropicalis)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Sus scrofa)


name: PTPN1 dephosphorylates PTK6 (Homo sapiens)


name: (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Bos taurus)


name: SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Rattus norvegicus)


name: AMBRA1 binds DYNLL1,DYNLL2 (Canis familiaris)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Sus scrofa)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] => 16beta,17beta-estriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + neryl diphosphate = 1,8-cineole + diphosphate


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Gallus gallus)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(in) + ATP + H2O <=> 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: Degradation of multiubiquitinated Securin (Homo sapiens)


name: HNF1A-dependent synthesis of HNF4A (Homo sapiens)


name: 4alpha-carboxyzymosterol + NAD(+) = CO2 + NADH + zymosterone


name: dimethyl sulfoxide(in) = dimethyl sulfoxide(out)


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Gallus gallus)


name: SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region (Homo sapiens)


name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate (Mus musculus)


name: (-)-2'-epi-GR24 + H2O <=> (-)-2'-epi-GR24 ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one


name: PARK2 autoubiquitinates (Saccharomyces cerevisiae)


name: AH2 + kynurenate + O2 => 7,8-dihydro-7,8-dihydroxykynurenate + A


name: SEC31:SEC13 and v-SNARE recruitment (Dictyostelium discoideum)


name: EPCAM binds itself to form homotypic cell adhesion (Rattus norvegicus)


name: melibiose(out) + Na(+)(out) => melibiose(in) + Na(+)(in)


name: ATP + glycyl-L-glutamate(out) + H2O <=> ADP + glycyl-L-glutamate(in) + H(+) + phosphate


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-ethanolamine = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: EVL:PPL heterodimer binds the inner surface of the plasma membrane (Sus scrofa)


name: PTHP is reduced to BH4 by sepiapterin reductase (SPR) (Mus musculus)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Homo sapiens)


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Homo sapiens)


name: UNG glycosylase mediated recognition and binding of an uracil opposite to a guanine (Homo sapiens)


name: RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Rattus norvegicus)


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Mus musculus)


name: RAC2 GEFs activate RAC2 (Canis familiaris)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Mus musculus)


name: alpha-D-mannose derivative + UDP-alpha-D-glucose = 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H(+) + UMP


name: p53 positively regulates transcription of MIR34 microRNAs (Homo sapiens)


name: Platelet-derived TREM-1 ligand binds to TREM-1 (Mus musculus)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O => H(+) + hexadecanoate + sn-glycero-3-phosphoethanolamine


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Mus musculus)


name: a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Formation of Pol zeta complex (Drosophila melanogaster)


name: H2O + methyl salicylate = H(+) + methanol + salicylate


name: apo-Transferrin dissociates from the receptor complex (Homo sapiens)


name: LIG1 binds POLB at long-patch BER site (Sus scrofa)


name: 3-oxooctadecanoyl-CoA + H(+) + NADPH => 3-hydroxyoctadecanoyl-CoA + NADP(+)


name: (2E,6E)-farnesyl diphosphate + H2O => 4-epi-cubebol + diphosphate


name: all-trans-zeaxanthin + O2 => (3R)-3-hydroxy-8'-apo-beta-carotenal + 3beta-hydroxy-beta-cyclocitral


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Homo sapiens)


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Homo sapiens)


name: ATP + L-threonine = ADP + H(+) + O-phospho-L-threonine


name: 1-deoxy-D-xylulose + ATP = 1-deoxy-D-xylulose 5-phosphate + ADP + H(+)


name: apo-Transferrin dissociates from the receptor complex (Rattus norvegicus)


name: hydroxymethylbilane => H2O + uroporphyrinogen III


name: Masitinib-resistant KIT mutants do not bind masitinib (Homo sapiens)


name: Deubiquitinated PTEN translocates to the cytosol (Rattus norvegicus)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Sus scrofa)


name: LIPs hydrolyze TG to DAG and LCFA (Dictyostelium discoideum)


name: MIOX oxidises Ins to GlcA (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-glycerol <=> 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: Hyperphosphorylated IRAK1 associates with TRAF6 (Homo sapiens)


name: Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Canis familiaris)


name: H2O + L-homocarnosine <=> 4-aminobutanoate + L-histidine


name: Exocytosis of ficolin-rich granule lumen proteins (Canis familiaris)


name: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Saccharomyces cerevisiae)


name: SUMOylation of RAD52 with SUMO1 (Xenopus tropicalis)


name: Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Mus musculus)


name: dynorphin A-(1-12) + L-lysine => dynorphin A-(1-13) + H2O


name: Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Sus scrofa)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = n acetate + chitosan


name: JLP interacts with CDO complex (Homo sapiens)


name: SCD desaturates ST-CoA to OLE-CoA (Dictyostelium discoideum)


name: Allergen dependent IgE bound FCERI aggregation (Homo sapiens)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Homo sapiens)


name: H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate => L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate


name: desmethylxanthohumol + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + xanthohumol


name: H2O + stigmasteryl 3-beta-D-glucoside = D-glucose + stigmasterol


name: SRC-1 phosphorylates p-Y397-PTK2 (Canis familiaris)


name: (9R)-hydroxy-(10E,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase]


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Caenorhabditis elegans)


name: Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate


name: (3R)-3-isocyanylbutanoate + ATP + H(+) = (3R)-3-isocyanylbutanoyl-AMP + diphosphate


name: 2-oxoglutarate + L-histidine <=> 3-(imidazol-5-yl)pyruvate + L-glutamate


name: SALL4 binds the PTEN gene promoter (Homo sapiens)


name: CHEK2 phosphorylates TP53 (Drosophila melanogaster)


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Rattus norvegicus)


name: a neolactoside nLc4Cer(d18:0) + L-fucose => a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:0) + H2O


name: IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Bos taurus)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Dictyostelium discoideum)


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate <=> 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Caenorhabditis elegans)


name: p-S MAPKAPK5 phosphorylates HSPB1 (Bos taurus)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O = (9Z,12Z)-octadecadienoate + di-(9Z,12Z)-octadecadienoylglycerol + H(+)


name: 4-methylsulfanyl-2-oxobutanoate + L-tyrosine = 3-(4-hydroxyphenyl)pyruvate + L-methionine


name: DDHD1,2 hydrolyse PA (Xenopus tropicalis)


name: Aquaporins passively transport urea out of cells (Danio rerio)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Gallus gallus)


name: pregnenolone sulfate(out) <=> pregnenolone sulfate(in)


name: 4-aminobutanoate(in) + L-glutamate(out) = 4-aminobutanoate(out) + L-glutamate(in)


name: p-S158,221-HuR binds mRNA (Mus musculus)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Mus musculus)


name: cob(II)inamide-[corrinoid adenosyltransferase] => apo-[corrinoid adenosyltransferase] + cob(II)inamide


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Caenorhabditis elegans)


name: Metabotropic glutamate receptors bind glutamate (Gallus gallus)


name: Dimerization of procollagen type VI (Homo sapiens)


name: an N-acyl-D-glutamate + H2O <=> a carboxylate + D-glutamate


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Canis familiaris)


name: 2-carboxy-L-lyxonate + H(+) = CO2 + L-lyxonate


name: H(+) + H2O + L-phenylalanine + O2 => 2-phenylacetaldehyde + CO2 + H2O2 + NH4(+)


name: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + H(+) + L-tyrosine methyl ester 4-sulfate


name: Translocation of PDGF from ER to Golgi (Sus scrofa)


name: MET phosphorylates CBL (Caenorhabditis elegans)


name: 17-hydroxy-3-oxochol-4-en-22-oyl-CoA => 3-oxochola-4,17-dien-22-oyl-CoA + H2O


name: an L-glycol + NADP(+) => a 2-hydroxycarbonyl + H(+) + NADPH


name: FMNH2 + NADH + O2 + thymine <=> (Z)-2-methylureidoacrylate + FMN + H(+) + H2O + NAD(+)


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Caenorhabditis elegans)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) => 2 H(+) + L-erythro-biopterin + 2 NADPH


name: ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter (Homo sapiens)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Canis familiaris)


name: H(+) + S-adenosyl-L-homocysteine + scoparone => S-adenosyl-L-methionine + scopoletin


name: H3-H4 histone complex chaperone activity


name: [protein]-dithiol + [thioredoxin]-disulfide <=> [protein]-disulfide + [thioredoxin]-dithiol


name: DENND5A,B exchange GTP for GDP on RAB39 (Sus scrofa)


name: PC is converted to PS by PTDSS1 (Homo sapiens)


name: Interaction of Bcl10 to CARMA1 (Rattus norvegicus)


name: Estrogen-responsive GREB1 gene transcription (Homo sapiens)


name: RHOV binds effectors at the plasma membrane (Dictyostelium discoideum)


name: (S)-miconazole(out) + ADP + H(+) + phosphate => (S)-miconazole(in) + ATP + H2O


name: ATP + H2O + tauroursodeoxycholate(in) = ADP + H(+) + phosphate + tauroursodeoxycholate(out)


name: H2O + L-threonyl-tRNA(Val) <=> L-threonine + tRNA(Val)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Homo sapiens)


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Sus scrofa)


name: (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH => (6S,9R)-vomifoliol + NAD(+)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Dictyostelium discoideum)


name: 15-oxoprostaglandin F2alpha + H(+) + NADPH => NADP(+) + prostaglandin F2alpha


name: Activated CEBPB binds CDKN2B promoter (Homo sapiens)


name: Interaction of PAK1 with Rac1-GTP (Bos taurus)


name: CK2 phosphorylates PDCL (Drosophila melanogaster)


name: hexadecanoyl-CoA + N-terminal L-cysteinyl-[protein] = CoA + H(+) + N-terminal N-hexadecanoyl-L-cysteinyl-[protein]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Xenopus tropicalis)


name: De novo formation of eIF2:GTP (Drosophila melanogaster)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Bos taurus)


name: EGR2, SOX10 and SMARCA4 bind the MPZ gene (Homo sapiens)


name: [L-4-(L-arginin-2-N-yl)aspartate](n) + ATP + L-aspartate => [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + H(+) + phosphate


name: (5R)-hydroxy-beta-trans-bergamotene + O2 <=> (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + H2O


name: SLC7A3 (CAT-3)-mediated uptake of cationic amino acids (Drosophila melanogaster)


name: LIG1 binds POLB at long-patch BER site (Mus musculus)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Schizosaccharomyces pombe)


name: purine nucleoside transmembrane transporter activity


name: glycolate + GMP + H(+) => H2O + N(2)-(1-hydroxy-2-oxoethyl)-GMP


name: 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate => ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide


name: H2O + octanoyl-CoA => adenosine 3',5'-bisphosphate + 2 H(+) + S-octanoyl-4'-phosphopantetheine


name: a long-chain primary fatty alcohol + NADP(+) => a long-chain fatty aldehyde + H(+) + NADPH


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Mus musculus)


name: KRAS4B is phosphorylated on serine 181 (Mus musculus)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Xenopus tropicalis)


name: c-src associates with Cx43 in gap junctions (Rattus norvegicus)


name: kinetin UDP glycosyltransferase activity


name: a medium-chain fatty aldehyde + H2O + NAD(+) = a medium chain fatty acid + 2 H(+) + NADH


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Rattus norvegicus)


name: CoA + vinorine => 16-epivellosimine + acetyl-CoA


name: Phosphorylation of CRMPs by GSK3beta (Bos taurus)


name: H(+) + NADPH + progesterone => 5alpha-pregnane-3,20-dione + NADP(+)


name: H(+) + N(6),N(6)-dimethyl-L-lysine <=> CO2 + N,N-dimethyl-cadaverine


name: 2-oxoglutarate + L-lysyl-[collagen] + O2 => (5R)-5-hydroxy-L-lysyl-[collagen] + CO2 + succinate


name: (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + CO2 + CoA


name: 3,4-dihydroxybenzaldehyde + AH2 + tyramine = A + H2O + norbelladine


name: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside => 7-O-methylvitexin 2''-O-beta-L-rhamnoside + H(+) + S-adenosyl-L-homocysteine


name: 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide => beta-nicotinamide D-ribonucleotide + diphosphate


name: CYP1A2, 3A4 oxidise AFB1 to AFNBO (Xenopus tropicalis)


name: a ganglioside GM1b (d18:1(4E)) + H2O <=> a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate


name: Formation of the MLL1 complex (Gallus gallus)


name: platelet activating factor receptor activity


name: MAOA:FAD deaminates 3MT to HVA (Dictyostelium discoideum)


name: (2-aminobenzoyl)acetate + H(+) + octanoyl-CoA <=> 2-heptyl-4(1H)-quinolone + CO2 + CoA + H2O


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Xenopus tropicalis)


name: LMCD1 binds GATA6, sequestering it (Drosophila melanogaster)


name: O2 + piceatannol => 3,4-dihydroxybenzaldehyde + 3,5-dihydroxybenzaldehyde


name: Cysteine is degraded to serine and H2S (Sus scrofa)


name: 5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine = [LarE protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: 3-acetamidopropanal + H2O2 + spermidine => H2O + N(1)-acetylspermine + O2


name: GDIs block activation of RHOA (Homo sapiens)


name: Phosphorylated TAK1 leaves activated TLR receptor complex (Rattus norvegicus)


name: 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)


name: HDAC3 containing complexes deacetylate histone (Homo sapiens)


name: (2E)-decenoyl-CoA + FADH2 => decanoyl-CoA + FAD + H(+)


name: Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE (Homo sapiens)


name: Procollagen triple helix formation (Homo sapiens)


name: p-STAT5 dissociates from EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)


name: Dephosphorylation of CK2-modified condensin I (Schizosaccharomyces pombe)


name: GNRHR binds GNRHR peptide agonists (Gallus gallus)


name: ASIC3 channel blockers bind ASIC3 trimer (Gallus gallus)


name: (9Z)-hexadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) => (9Z)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: H(+) + L-alanine + sulfite => 3-sulfino-L-alanine + H2O


name: NRF1:PPARGC1B binds the ATP5B promoter (Homo sapiens)


name: OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Danio rerio)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Sus scrofa)


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 1-(9Z,12Z-octadecadienoyl)-2-acyl-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: (9S,10R)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-(9S,10R)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ABCB1 transports xenobiotics out of the cell (Mus musculus)


name: adenosine + H2O + 2 O2 = 9-riburonosyladenine + H(+) + 2 H2O2


name: SGTA binds Tail-anchored protein (Mus musculus)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Xenopus tropicalis)


name: phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] = (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit]


name: "C-phycoerythrin beta-cysteine-48/59 phycoerythrobilin lyase"


name: NBEA translocates to the nucleus (Homo sapiens)


name: 4-amino-4-deoxyprephenate + NAD(+) = 3-(4-aminophenyl)pyruvate + CO2 + H(+) + NADH


name: (R)-glycerate + 2 H(+) + NADPH => D-glyceraldehyde + H2O + NADP(+)


name: deoxyherqueinone + H(+) + S-adenosyl-L-homocysteine => (2'R)-atrovenetin + S-adenosyl-L-methionine


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: ATP + dGMP + L-aspartate <=> (2S)-2-amino-2'-deoxyadenylo-succinate + ADP + 2 H(+) + phosphate


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Rattus norvegicus)


name: 2 H(+) + reduced [rubredoxin] + superoxide <=> H2O2 + oxidized [rubredoxin]


name: 9H-fluoren-9-ol + NADP(+) = 9H-fluoren-9-one + H(+) + NADPH


name: 5alpha-pregnan-20beta-ol-3-one + NAD(+) <=> 5alpha-pregnane-3,20-dione + H(+) + NADH


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Homo sapiens)


name: (25S)-5beta-spirostan-3beta-ol + UDP-alpha-D-glucose => (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP


name: nor-toralactone + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + toralactone


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Dictyostelium discoideum)


name: SPHK2 phosphorylates sphingoid (Drosophila melanogaster)


name: S-adenosyl-L-methionine + uridine(44) in tRNA(Ser) = 2'-O-methyluridine(44) in tRNA(Ser) + H(+) + S-adenosyl-L-homocysteine


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Plasmodium falciparum)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Bos taurus)


name: glycyl-L-glutamate(out) + 3 H(+)(out) = glycyl-L-glutamate(in) + 3 H(+)(in)


name: 2xTPK1:Mg2+ phosphorylates THMN (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => a monoacyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: SMOX-3 oxidises SPN to SPM (Canis familiaris)


name: cholesterol + hexadecanoyl-CoA => cholesteryl hexadecanoate + CoA


name: AMP + diphosphate + L-alanyl-tRNA(Ala) => ATP + L-alanine + tRNA(Ala)


name: Formation of the CTF18-RFC(7s) complex (Caenorhabditis elegans)


name: PIAS2,3,4 SUMOylate RORA with SUMO1 (Mus musculus)


name: alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose => alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-1-diphospho-di-trans,octa-cis-undecaprenol + dTDP + H(+)


name: SH2 domain of Src binds to the active receptor (Danio rerio)


name: (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) <=> catechol + H(+) + NADPH


name: CBL ubiquitinates FRS2 and FGFR3 (Gallus gallus)


name: 3-hydroxy-L-kynurenine(out) + L-tryptophan(in) => 3-hydroxy-L-kynurenine(in) + L-tryptophan(out)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Schizosaccharomyces pombe)


name: (3R)-hydroxydodecanoyl-[ACP] => (2E)-dodecenoyl-[ACP] + H2O


name: RAC1 and CDC42 activate PAK2 (Canis familiaris)


name: USP24 deubiquitinates DDB2 (Rattus norvegicus)


name: 2',3'-cGAMP(in) + ATP + H2O = 2',3'-cGAMP(out) + ADP + H(+) + phosphate


name: FAD + glutaryl-CoA + 2 H(+) => (2E)-butenoyl-CoA + CO2 + FADH2


name: a 2'-deoxyadenosine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + O2


name: epoxypheophorbide a + H2O => H(+) + red chlorophyll catabolite


name: Alpha-1-Microglobulin is cleaved (Rattus norvegicus)


name: IL10 dimer binds IL10RA:JAK1 (Homo sapiens)


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate + NH4(+) => 2-amino-2-deoxy-D-gluconate 6-phosphate


name: alpha,alpha-trehalose 6-phosphate + phosphate = beta-D-glucose 1-phosphate + D-glucose 6-phosphate


name: PGRMC2 binds Hemes (Schizosaccharomyces pombe)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Drosophila melanogaster)


name: soyasapogenol A + UDP-alpha-D-glucuronate = H(+) + soyasapogenol A 3-O-beta-D-glucuronate + UDP


name: D-galactosamine 6-phosphate + H2O = D-tagatopyranose 1-phosphate + NH4(+)


name: adenosine(1832) in 18S rRNA + S-adenosyl-L-methionine => H(+) + N(6)-methyladenosine(1832) in 18S rRNA + S-adenosyl-L-homocysteine


name: N-formimidoylglycine => H2O + imidazol-4-one


name: diphosphate hydrolysis-driven proton transmembrane transporter activity


name: (9Z)-hexadecenoyl-CoA + FAD + H(+) => (2E,9Z)-hexadecadienoyl-CoA + FADH2


name: 2',3'-cyclophospho-GMP + H2O => 3'-GMP + H(+)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Bos taurus)


name: ATP + chenodeoxycholate + CoA => AMP + chenodeoxycholoyl-CoA + diphosphate


name: Joining of adjacent Okazaki fragments (Mus musculus)


name: ATM phosphorylates EYA1-4 (Canis familiaris)


name: NT5E:Zn2+ hydrolyses NAD+ (Rattus norvegicus)


name: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine <=> dihydromacarpine + H(+) + S-adenosyl-L-homocysteine


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)


name: dihydrobisanhydrobacterioruberin + diphosphate => dimethylallyl diphosphate + H2O + isopentenyldehydrorhodopin


name: MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Sus scrofa)


name: L-phenylalanine(in) + Na(+)(in) => L-phenylalanine(out) + Na(+)(out)


name: PIAS4 SUMOylates VDR with SUMO2 (Drosophila melanogaster)


name: 2'-O-methyluridine(2479) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(2479) in 23S rRNA


name: H2O + sn-glycero-3-phospho-(1'-rac-glycerol) => glycerol + H(+) + sn-glycerol 3-phosphate


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Sus scrofa)


name: ATP-dependent histone chaperone activity


name: galactarate <=> 5-dehydro-4-deoxy-D-glucarate + H2O


name: 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O => 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxylate + H(+) + holo-[ACP]


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Rattus norvegicus)


name: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+) = a (3R)-2'-hydroxyisoflavanone + H(+) + NADPH


name: bromide + S-adenosyl-L-methionine => bromomethane + S-adenosyl-L-homocysteine


name: fumarylacetoacetate => fumarate + acetoacetate (Dictyostelium discoideum)


name: acetoacetate(out) + Na(+)(out) => acetoacetate(in) + Na(+)(in)


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Canis familiaris)


name: (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + CO2 + CoA


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+) => H2O + progoitrin


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus (Canis familiaris)


name: O2 + reduced [NADPH--hemoprotein reductase] + sophoradiol => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + soyasapogenol B


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Gallus gallus)


name: NSF ATPase activity dissociates cis-SNARE (Mus musculus)


name: a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SCF-FBXL7 ubiquitinates AURKA (Mus musculus)


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Dictyostelium discoideum)


name: PHF8 demethylates MeK21-histone H4 (Caenorhabditis elegans)


name: KAT5 acetylates ATM at shortened telomeres (Gallus gallus)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine = 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: L-glutamate(in) + N-acetyl-L-cysteine(out) <=> L-glutamate(out) + N-acetyl-L-cysteine(in)


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Schizosaccharomyces pombe)


name: 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2 => 3-hydroxyanthranilate + O2


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Danio rerio)


name: H(+)(out) + L-phenylalanyl-L-phenylalanine(out) => H(+)(in) + L-phenylalanyl-L-phenylalanine(in)


name: PTK6 phosphorylates ARHGAP35 (Caenorhabditis elegans)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Mus musculus)


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Rattus norvegicus)


name: dichloromethane + H2O = 2 chloride + formaldehyde + 2 H(+)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Saccharomyces cerevisiae)


name: D-glucose 6-phosphate + TDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + H(+) + TDP


name: 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in single-stranded DNA + O2 = a 2'-deoxycytidine in single-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: GNLY is transferred to the phagosome (Homo sapiens)


name: CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) (Mus musculus)


name: SGMS1 transfers phosphocholine onto ceramide (Sus scrofa)


name: Association of procollagen type XXVII (Bos taurus)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate => H2O + leukotriene A4


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: H(+) + L-dopa + NADH => 3-(3,4-dihydroxyphenyl)propanoate + NAD(+) + NH4(+)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Bos taurus)


name: 3'-phosphoadenylyl sulfate + a thiol => adenosine 3',5'-bisphosphate + H(+) + S-alkyl thiosulfate


name: p-PKR dimer phosphorylates SPHK1 (Mus musculus)


name: (3R)-hydroxyhexadecanedioyl-CoA => (2E)-hexadecenedioyl-CoA + H2O


name: an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-alpha-D-galactose <=> an alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H(+) + UDP


name: diphosphate + dTDP-alpha-D-glucose => alpha-D-glucose 1-phosphate + dTTP + H(+)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH <=> 1-hexadecanoyl-2-(9-hydroxynonanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: 7alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH => chenodeoxycholate + NAD(+)


name: H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Homo sapiens)


name: glutathione + H(+) + hydrogen sulfide + ubiquinone-10 => S-sulfanylglutathione + ubiquinol-10


name: Unwinding DNA for the nascent transcript (Homo sapiens)


name: 8-oxo-dGMP + 2 H(+) + 2 phosphate => 8-oxo-dGTP + 2 H2O


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde = H(+) + H2O + quinolinate


name: aurachin C + H(+) + NADH + O2 <=> 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + H2O + NAD(+)


name: NLRP3 activation by small molecules (Rattus norvegicus)


name: TRIM27 polyubiquitinates PTEN (Mus musculus)


name: ATM binds PEX5 (Drosophila melanogaster)


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + NAD(+) = 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + NADH


name: NADP(+) + prostaglandin E1 => 15-oxoprostaglandin E1 + H(+) + NADPH


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Drosophila melanogaster)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Homo sapiens)


name: neutral L-amino acid:sodium symporter activity


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Mus musculus)


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 (Rattus norvegicus)


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + talarodiene


name: PEX19:class I PMP binds PEX3 (Mus musculus)


name: SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Caenorhabditis elegans)


name: 3-oxodecanoyl-[ACP] + CO2 + CoA => H(+) + malonyl-[ACP] + octanoyl-CoA


name: (2E,6E)-farnesyl diphosphate + H(+) + NADPH + O2 <=> (2E,6E)-omega-hydroxy-farnesyl diphosphate + H2O + NADP(+)


name: CDC42 binds effectors at the plasma membrane (Canis familiaris)


name: GSDMD (1-275) binds cardiolipin (Mus musculus)


name: C20 sphinganine + NADP(+) <=> 3-oxoeicosasphinganine + H(+) + NADPH


name: Cho transports from the extracellular space to the cytosol (Sus scrofa)


name: N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: H2O + Met-enkephalin-Arg-Phe => L-arginyl-L-phenylalanine + Met-enkephalin


name: PCSK1 hydrolyzes proGIP to GIP (Homo sapiens)


name: 3 H(+) + O2 + pheophorbide a + 2 reduced [2Fe-2S]-[ferredoxin] <=> epoxypheophorbide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ASAP1 stimulates GTPase activity of ARF4 (Sus scrofa)


name: NEDD4L ubiquitinates SMAD2/3 (Canis familiaris)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Bos taurus)


name: PIAS1 SUMOylates THRB with SUMO1. (Gallus gallus)


name: carbonyl sulfide + H(+) + hydrogen sulfide => carbon disulfide + H2O


name: a 4-hydroxynonen-1-ol + NADP(+) => a 4-hydroxynonenal + H(+) + NADPH


name: NMT1/2 transfer MYS to GNAT1 (Mus musculus)


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate + L-glutamate = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-glutamate


name: H(+) + L-cysteine + tRNA(Pro) => H2O + L-cysteinyl-tRNA(Pro)


name: 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 (Homo sapiens)


name: Thrombin-activated PARs:G12/13 (active) dissociate (Caenorhabditis elegans)


name: a 5'-end (5'-phospho)-ribonucleoside-RNA + S-adenosyl-L-methionine => a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine


name: Expression of ZIC1 in the neural plate border (Homo sapiens)


name: LINC01139 promotes phosphorylation of HIF1A by PTK6 (Rattus norvegicus)


name: [(3R)-hydroxybutanoate](n) + H2O = (3R)-hydroxybutanoate trimer + [(3R)-hydroxybutanoate](n-3) + H(+)


name: dimethylallyl diphosphate + 3 isopentenyl diphosphate <=> 3 diphosphate + nerylneryl diphosphate


name: 4 Fe(II)-[cytochrome cL] + formate + 5 H(+) => 4 Fe(III)-[cytochrome cL] + H2O + methanol


name: 4-methylene-L-glutamine + H2O => 4-methylene-L-glutamate + NH4(+)


name: Association of procollagen type XI (Bos taurus)


name: H(+)(out) + N-acetyl-L-aspartyl-L-glutamate(out) = H(+)(in) + N-acetyl-L-aspartyl-L-glutamate(in)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Xenopus tropicalis)


name: 5-HT2 receptor can bind serotonin (Danio rerio)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Insulin secretory granule translocates to cell cortex (Homo sapiens)


name: PAK phosphorylates p21 RAF1 on S338 (Xenopus tropicalis)


name: HNF1A-dependent synthesis of FOXA3 (Homo sapiens)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Gallus gallus)


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Xenopus tropicalis)


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Gallus gallus)


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Drosophila melanogaster)


name: HuR:mRNA complex translocates from the nucleus to the cytosol (Drosophila melanogaster)


name: RCHY1 monoubiquitinates POLH (Bos taurus)


name: PP2A dephosphorylates p-RHO to RHO (Rattus norvegicus)


name: Phosphorylation of WWTR1 (TAZ) by LATS2 (Gallus gallus)


name: Formation of RAD52 heptameric ring structure complexes (Bos taurus)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Mus musculus)


name: (S)-scoulerine + H(+) + H2O2 => (S)-reticuline + O2


name: endoribonuclease activity involved in viral induction of host mRNA catabolic process


name: ST8SIA5 transfers Neu5Ac to gangliosides (Mus musculus)


name: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome (Bos taurus)


name: 2-oxoglutarate + 3,5-diiodo-L-tyrosine <=> 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate


name: maleate(in) + sulfate(out) <=> maleate(out) + sulfate(in)


name: inositol hexakisphosphate 4-kinase activity


name: D-alanyl-5'-AMP + diphosphate => ATP + D-alanine + H(+)


name: butanal + CoA + NADP(+) => butanoyl-CoA + H(+) + NADPH


name: PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 (Rattus norvegicus)


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Bos taurus)


name: RNF152 polyubiquitinates RRAGA (Dictyostelium discoideum)


name: Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 (Gallus gallus)


name: UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity


name: NEIL1,NEIL2 recruits POLB to incised AP site (Canis familiaris)


name: The exocyst complex binds to RAB3IP in the ciliary targeting complex (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)


name: CANX dissociates from IL27:EBI3 (Sus scrofa)


name: 2-oxoglutarate + L-aspartyl-[ankyrin-repeat domain protein] + O2 => (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: CYP19A1 hydroxylates ANDST to E1 (Danio rerio)


name: H2O + NADP(+) + omega-hydroxy-3,7,11,15-tetramethyl-hexadecanoate => 3,7,11,15-tetramethylhexadecanoate + H(+) + NADPH + O2


name: (6E)-8-oxogeranial + H(+) + NADPH => (6E)-8-hydroxygeranial + NADP(+)


name: FECH binds Fe2+ to PRIN9 to form heme (Mus musculus)


name: ATP + thiamine diphosphate => ADP + thiamine triphosphate


name: (+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Rattus norvegicus)


name: ADP and Pi bind to ATPase (Caenorhabditis elegans)


name: molybdenum cofactor sulfurtransferase activity


name: ATP(out) + dATP(in) => ATP(in) + dATP(out)


name: p-Y694-STAT5A, p-STAT5B dimerizes (Homo sapiens)


name: Cdt1 is displaced from the pre-replicative complex. (Drosophila melanogaster)


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Rattus norvegicus)


name: Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Bos taurus)


name: UROD decarboxylates URO3 to COPRO3 (Sus scrofa)


name: CDKN1A gene transcription is stimulated by FOXO1,FOXO3,FOXO4 (Homo sapiens)


name: ESR1 binds to TFF1 gene promoter (Drosophila melanogaster)


name: a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + H(+) + UDP


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Danio rerio)


name: 2,5-diformylfuran + H2O => 2-(dihydroxymethyl)-5-formylfuran


name: UGT1A3 lactonizes ATV to ATVL (Homo sapiens)


name: acetaldehyde + D-glyceraldehyde 3-phosphate => 2-deoxy-D-ribose 5-phosphate


name: (S)-3-(imidazol-5-yl)lactate + NAD(+) <=> 3-(imidazol-5-yl)pyruvate + H(+) + NADH


name: (9S,13S,15Z)-12-oxophyto-10-15-dienoate + ATP + CoA => (10Z,15Z)-12-oxophytodienoyl-CoA + AMP + diphosphate


name: Homer1,2,3 binds mGluR1a,5 (Canis familiaris)


name: octadecanoyl-CoA + sphinganine <=> CoA + H(+) + N-(octadecanoyl)-sphinganine


name: HEXA cleaves the terminal GalNAc from DS (Homo sapiens)


name: a 1-acyl-sn-glycero-3-phosphocholine + a cardiolipin => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Homo sapiens)


name: Kinesin-5 is a homotetramer (Saccharomyces cerevisiae)


name: 3-(carbamoylamino)-2-methylpropanoate + 2 H(+) + H2O => (R)-3-amino-2-methylpropanoate + CO2 + NH4(+)


name: an N-acylsphing-4-enine + ATP <=> ADP + an N-acylsphing-4-enine 1-phosphate + H(+)


name: CES1,CES2 hydrolyze ASA- to ST (Bos taurus)


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Caenorhabditis elegans)


name: ATP + butanoate + H(+) + NADPH <=> AMP + butanal + diphosphate + NADP(+)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPC (Homo sapiens)


name: NADH + O2 + rifampicin = H(+) + H2O + NAD(+) + rifampicin para-naphthoquinone carboxamide


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + CoA + H(+) => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O


name: glycerophospholipid acyltransferase (CoA-dependent) activity


name: CHEK1 is recruited to resected DNA DSBs (Sus scrofa)


name: (R)-salsolinol + S-adenosyl-L-methionine = H(+) + N-methyl-(R)-salsolinol + S-adenosyl-L-homocysteine


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Mus musculus)


name: Formation of RAD50:MRE11 complex (Mus musculus)


name: Beta-catenin migrates to the nucleus (Homo sapiens)


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)


name: Fibrillin C-terminal processing (Canis familiaris)


name: PARVB interacts with Alpha-actinin (Bos taurus)


name: ATP + Co(2+)(out) + H2O => ADP + Co(2+)(in) + H(+) + phosphate


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: IL6:IL6R-2 binds IL6ST-2 (Canis familiaris)


name: S100A7 or S100A7A binds Zn2+ (Sus scrofa)


name: Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes (Homo sapiens)


name: Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Mus musculus)


name: 2 (3R)-hydroxydecanoyl-[ACP] + H2O <=> (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + H(+) + 2 holo-[ACP]


name: SYK binds to integrin alphaIIb beta3 (Rattus norvegicus)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Rattus norvegicus)


name: 1-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O => 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: acryloyl-CoA + CO2 + NADPH => (S)-methylmalonyl-CoA + NADP(+)


name: Formation of allysine by LOX (Homo sapiens)


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Drosophila melanogaster)


name: NCOA1 recruits EP300 to TGFA promoter (Gallus gallus)


name: an N-terminal trimethyl-L-alpha-aminoacyl-[protein] + 3 H(+) + 3 S-adenosyl-L-homocysteine => an N-terminal L-alpha-aminoacyl-[protein] + 3 S-adenosyl-L-methionine


name: 8-oxo-dGTP + 2 H2O = 8-oxo-dGMP + 2 H(+) + 2 phosphate


name: 2-(phosphinatomethylidene)butanedioate + H2O => phosphinomethylisomalate


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Homo sapiens)


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Drosophila melanogaster)


name: (2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin => 6-linalyl-2-O,3-dimethylflaviolin + diphosphate


name: (S)-malate(in) + H(+)(out) + phosphate(out) => (S)-malate(out) + H(+)(in) + phosphate(in)


name: p-T774-PKN1 phosphorylates CDC25C (Schizosaccharomyces pombe)


name: 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> 9beta-pimara-7,15-diene-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 17beta-estradiol 3-sulfate(out) + 2 Na(+)(out) => 17beta-estradiol 3-sulfate(in) + 2 Na(+)(in)


name: a 1,2-diacyl-sn-glycerol(in) = a 1,2-diacyl-sn-glycerol(out)


name: a dihydroceramide + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a phytoceramide + 2 Fe(III)-[cytochrome b5] + H2O


name: phycocyanobilin-L-cysteinyl(84)-[allophycocyanin alpha-subunit] = (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[allophycocyanin alpha-subunit]


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Xenopus tropicalis)


name: O2 + octanedioyl-CoA <=> (2E)-octenedioyl-CoA + H2O2


name: STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Rattus norvegicus)


name: phosphate + pyridoxamine <=> H2O + pyridoxamine 5'-phosphate


name: EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Sus scrofa)


name: (S)-3-hydroxybutanoate(out) + H(+)(out) => (S)-3-hydroxybutanoate(in) + H(+)(in)


name: CDK5 phosphorylates NTRK2 (Homo sapiens)


name: CTP + N,N-diacetyllegionaminate <=> CMP-N,N-diacetyllegionaminate + diphosphate


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Canis familiaris)


name: 3-oxooctanoyl-CoA + H(+) + NADPH => (3R)-hydroxyoctanoyl-CoA + NADP(+)


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)


name: Formation of nonameric complex (Xenopus tropicalis)


name: NFE2L2 translocates from cytosol to nucleoplasm (Gallus gallus)


name: deoxycholate + glycine => glycodeoxycholate + H2O


name: KSPG is secreted from the cell (Mus musculus)


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Mus musculus)


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + H(+) = H2O + norlichexanthone


name: H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol <=> a fatty acid + H(+) + long chain 2-acyl-3-O-beta-D-galactosyl-sn-glycerol


name: butan-2-one + H(+) + NADH + NH4(+) => (S)-sec-butylamine + H2O + NAD(+)


name: 6-sulfo-D-glucono-1,5-lactone + H(+) + NADPH => D-glucose 6-sulfate + NADP(+)


name: GDP-valienol + validamine 7-phosphate <=> GDP + H(+) + validoxylamine A 7'-phosphate


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Canis familiaris)


name: Aquaporins passively transport urea into cells (Gallus gallus)


name: dUTP(out) + UTP(in) <=> dUTP(in) + UTP(out)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxy-fatty acyl)-sphingoid base = a 1,2-diacyl-sn-glycerol + inositol-1-phospho-N-(2-hydroxy-fatty acyl)-sphingoid base


name: Separation of sister chromatids (Homo sapiens)


name: glutarate(in) + succinate(out) <=> glutarate(out) + succinate(in)


name: thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Dictyostelium discoideum)


name: Ferrous iron reduces the BH3 radical back to BH4 (Homo sapiens)


name: A + 2 cob(II)alamin + 2 H(+) + 2 H2O = AH2 + 2 aquacob(III)alamin


name: cortisol + NAD(+) => cortisone + H(+) + NADH


name: CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) (Danio rerio)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Sus scrofa)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Homo sapiens)


name: CoA + H(+) + N-acetyltyramine => acetyl-CoA + tyramine


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose <=> alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer(d18:1(4E)) + H(+) + UDP


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + methanol


name: Phosphorylated FOXO1A is excluded from the nucleus (Danio rerio)


name: S100A7 or S100A7A binds Zn2+ (Xenopus tropicalis)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Caenorhabditis elegans)


name: THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Drosophila melanogaster)


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Gallus gallus)


name: 2 H(+) + N-(carboxyaminomethyl)urea <=> CO2 + N-(aminomethyl)urea


name: General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Rattus norvegicus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + UMP <=> (6S)-5,6,7,8-tetrahydrofolate + 5-methyl-UMP + NADP(+)


name: Activated TrkA receptor internalizes to endosomes (Homo sapiens)


name: (1E,4E)-germacrene B + diphosphate => (2E,6E)-farnesyl diphosphate


name: L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + heptadecanoyl-CoA => 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphate + CoA


name: Activated FGFR2 phosphorylates FRS3 (Drosophila melanogaster)


name: Caspase-mediated cleavage of Desmoglein 2 (Caenorhabditis elegans)


name: H(+)(out) + L-fucose(out) => H(+)(in) + L-fucose(in)


name: H(+)(out) + L-alanyl-L-valine(out) => H(+)(in) + L-alanyl-L-valine(in)


name: telomerase RNA reverse transcriptase activity


name: [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] => [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Homo sapiens)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Gallus gallus)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Sus scrofa)


name: 4-hydroxy-3-all-trans-nonaprenylbenzoate + H(+) = 2-all-trans-nonaprenylphenol + CO2


name: (2E)-octenoyl-CoA + FADH2 => FAD + H(+) + octanoyl-CoA


name: 3-oxohexadecanedioyl-CoA + CoA = acetyl-CoA + tetradecanedioyl-CoA


name: K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Rattus norvegicus)


name: coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] => coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Phosphorylated OPTN translocates to the nucleus (Xenopus tropicalis)


name: 2-oxoglutarate + O2 + pentalenolactone E <=> CO2 + pentalenolactone F + succinate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: Formation of Cyclin E:Cdk2 complexes (Rattus norvegicus)


name: H2O + methanol + NADP(+) => H(+) + methane + NADPH + O2


name: cytosine(in) + H(+)(in) => cytosine(out) + H(+)(out)


name: (7S)-salutaridinol + NADP(+) <=> H(+) + NADPH + salutaridine


name: very long-chain fatty acid omega-hydroxylase activity


name: an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-very-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Drosophila melanogaster)


name: H2O + N(4)-acetylcytidine <=> acetate + cytidine + H(+)


name: GRK2 sequesters activated Gq (Xenopus tropicalis)


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Plasmodium falciparum)


name: PSAP(195-273) dimer binds PE (Dictyostelium discoideum)