name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Xenopus tropicalis)


name: 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+) => a 1-acylglycerone 3-phosphate + a long chain fatty alcohol


name: CDK1 phosphorylates NUP98 (Canis familiaris)


name: electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity


name: Phosphorylated YBX1 translocates to the nucleus (Homo sapiens)


name: SUMOylation of PML with SUMO3 (Bos taurus)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)


name: Endophilins recruit synaptojanins to the clathrin-coated pit (Gallus gallus)


name: [protein]-dithiol + [thioredoxin]-disulfide = [protein]-disulfide + [thioredoxin]-dithiol


name: 1-nitrocyclohexene + H(+) + NADPH => 1-nitrocyclohexan + NADP(+)


name: A + glutathione + methanethiol => AH2 + S-(methylsulfanyl)glutathione


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + CO2 + CoA


name: glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Canis familiaris)


name: Phosphorylation of SLP-76 by p-SYK (Mus musculus)


name: calcitriol + UDP-alpha-D-glucuronate <=> calcitriol 25-O-(beta-D-glucuronide) + H(+) + UDP


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acyl-sphingoid base <=> a 1,2-diacyl-sn-glycerol + an inositol-1-phosphoceramide


name: SLC35D2 exchanges UDP-D-glucose for UMP (Gallus gallus)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Drosophila melanogaster)


name: H2O + UDP-alpha-D-glucose <=> alpha-D-galactose 1-phosphate + 2 H(+) + UMP


name: N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-glucuronate => [hyaluronan](n+1) + H(+) + UDP


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Drosophila melanogaster)


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Bos taurus)


name: Addition of galactose by beta 4-galactosyltransferases (Homo sapiens)


name: TRAF3/or TRAF6 ubiquitination within dsRNA:MDA5:IPS1:TRAF3/TRAF6 complex (Gallus gallus)


name: H(+) + holo-[ACP] + octanoate => H2O + octanoyl-[ACP]


name: (2E,6E)-farnesyl diphosphate => (+)-aristolochene + diphosphate


name: 4-(hydroxyamino)quinoline N-oxide + H2O + 2 NAD(+) => 4-nitroquinoline N-oxide + 2 H(+) + 2 NADH


name: AH2 + Latia luciferin + 2 O2 => A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin


name: 5-methyluridine(54) in tRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(54) in tRNA


name: FeHM oxidises LDL,HDL (Rattus norvegicus)


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Mus musculus)


name: 2-oxoglutarate(out) + malonate(in) = 2-oxoglutarate(in) + malonate(out)


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Canis familiaris)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Xenopus tropicalis)


name: apo-[corrinoid adenosyltransferase] + cob(II)alamin <=> cob(II)alamin-[corrinoid adenosyltransferase]


name: CDC14A,B bind MAPK6 (Saccharomyces cerevisiae)


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Bos taurus)


name: ADPRM hydrolyses ADP-ribose to R5P and AMP (Bos taurus)


name: MCAT transfers Mal from Mal-CoA to NDUFAB1 (Schizosaccharomyces pombe)


name: 1-hexadecanoylglycerone 3-phosphate + pentadecan-1-ol <=> 1-O-pentadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: NTPDase5 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)


name: tBID binds to inactive BAK protein (Sus scrofa)


name: (9Z)-octadecenoate + ethanolamine => H2O + N-(9Z-octadecenoyl) ethanolamine


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Xenopus tropicalis)


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Schizosaccharomyces pombe)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine


name: SHP-1 and SHP-2 bind pBTLA (Mus musculus)


name: RRAGC,D exchanges GTP for GDP (Bos taurus)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Drosophila melanogaster)


name: a 2-hydroxy fatty acid + H2O => a 1,2-saturated fatty acid + H2O2


name: SEMA4D interacts with Plexin-B1:Met (Xenopus tropicalis)


name: Activated TP receptor binds G-protein  G13 (Canis familiaris)


name: acetyl-CoA + chloramphenicol => chloramphenicol 3-acetate + CoA


name: a tRNA with a 3' CCA end + diphosphate => a tRNA with a 3' CC end + ATP


name: 1,2-dioctanoyl-sn-glycero-3-diphosphate + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + H(+) + phosphate


name: PTHP is reduced to BH4 by sepiapterin reductase (SPR) (Canis familiaris)


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Rattus norvegicus)


name: ATP + glycocholate(in) + H2O <=> ADP + glycocholate(out) + H(+) + phosphate


name: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + AH2 + O2 => A + H2O + N(6)-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenosine(37) in tRNA


name: nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template (Homo sapiens)


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Rattus norvegicus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol


name: (R)-benzoin + NADP(+) = benzil + H(+) + NADPH


name: "benzil reductase [(R)-benzoin forming]"


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Saccharomyces cerevisiae)


name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA (Caenorhabditis elegans)


name: (S)-dihydroorotate + menaquinone-8 <=> menaquinol-8 + orotate


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Danio rerio)


name: 5,6-dihydrouracil + NADP(+) => H(+) + NADPH + uracil


name: ERBB4 gene expression is stimulated by ERBB4s80:ESR1 (Homo sapiens)


name: CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression (Drosophila melanogaster)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Schizosaccharomyces pombe)


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Schizosaccharomyces pombe)


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Gallus gallus)


name: p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN (Homo sapiens)


name: Phosphorylation of Cx43 by c-src (Gallus gallus)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Plasmodium falciparum)


name: Activation of PAKs by RAC1 and CDC42 (Homo sapiens)


name: Cytosolic PLK1 translocates to the nucleus (Drosophila melanogaster)


name: BMP2 binds to the receptor complex (Bos taurus)


name: H(+) + L-galactono-1,4-lactone + NADH => L-galactose + NAD(+)


name: ATP + lipid A disaccharide (E. coli) <=> ADP + H(+) + lipid IVA (E. coli)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Danio rerio)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Caenorhabditis elegans)


name: beta-D-Gal-(1<->1')-Cer + H(+) + sulfate => 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + H2O


name: a 1-acyl-sn-glycero-3-phosphocholine + CoA => an acyl-CoA + sn-glycerol 3-phosphocholine


name: PTGIR binds PTGIR agonists (Mus musculus)


name: 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP => sn-glycerol 3-phosphate + UDP-alpha-D-galactose


name: CDC42:GTP recruits DIAPH2-2 to kinetochores (Bos taurus)


name: N-myristoylation of eNOS (Dictyostelium discoideum)


name: GAA hydrolyzes lysosomal glycogen (Canis familiaris)


name: 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA <=> 1-octanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: UCHL3, SENP8 cleave NEDD8 (Schizosaccharomyces pombe)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Mus musculus)


name: (20S)-ginsenoside Rg1 + H2O <=> (20S)-ginsenoside F1 + D-glucose


name: malonate(in) + Na(+)(in) <=> malonate(out) + Na(+)(out)


name: 2 (R)-3-phenyllactate + 2 (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine <=> 8 AMP + 8 diphosphate + 8 H(+) + PF1022A + 4 S-adenosyl-L-homocysteine


name: CYP2C19 5-hydroxylates omeprazole (Caenorhabditis elegans)


name: 4-aminobutanoate + CO2 => H(+) + L-glutamate


name: GRB2:SOS interacts with p-KIT (Mus musculus)


name: N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-glucuronate = [hyaluronan](n+1) + H(+) + UDP


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Mus musculus)


name: D-galactonate transmembrane transporter activity


name: Encapsidation of SARS coronavirus genomic RNA (Homo sapiens)


name: ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Sus scrofa)


name: RANBP2 SUMOylates PML with SUMO2 (Drosophila melanogaster)


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Danio rerio)


name: beta-pinacene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Sus scrofa)


name: H(+)(out) + homoserine lactone(in) = H(+)(in) + homoserine lactone(out)


name: PKC alpha interacts with and phosphorylates KIT (Rattus norvegicus)


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Sus scrofa)


name: Ferriheme is transferred from Methemoglobin to Hemopexin (Homo sapiens)


name: YAP1 binds ZO-2 (TJP2) (Caenorhabditis elegans)


name: Formation of MSH1:PMS2 Complex (Rattus norvegicus)


name: diphosphate + UDP-N-acetyl-alpha-D-galactosamine => H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UTP


name: USP4 deubiquitinate TRAF2,TRAF6 (Mus musculus)


name: ARHGAP35 binds RASA1 (Drosophila melanogaster)


name: dehydrodolichyl diphosphate synthase activity


name: CoA + H(+) + N-(2-hydroxyhexacosanoyl)-sphinganine => 2-hydroxyhexacosanoyl-CoA + sphinganine


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine => Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: anthranilate + S-adenosyl-L-methionine <=> O-methyl anthranilate + S-adenosyl-L-homocysteine


name: Activation of Ca permeable AMPA receptors (Caenorhabditis elegans)


name: cortisol + H(+) + NADPH = 20beta-dihydrocortisol + NADP(+)


name: Homocysteine is degraded to oxobutanoate and H2S (Homo sapiens)


name: MSH3 variant:MSH2-defective DNA mismatch repair (Homo sapiens)


name: H2O + N-tetradecanoylethanolamine = ethanolamine + tetradecanoate


name: 5-hydroxythiophene-2-carbonyl-CoA + H2O => 4-carboxy-2-thioxobutanoyl-CoA


name: RANKL,sRANKL trimer binds RANK (Sus scrofa)


name: AKR1C3 reduces atRAL to atROL (Caenorhabditis elegans)


name: (9Z)-hexadecenoyl-[ACP] + L-lysyl-[protein] <=> H(+) + holo-[ACP] + N(6)-[(9Z)-hexadecenoyl]-L-lysyl-[protein]


name: RhCG mediates ammonium efflux out of kidney collecting duct cells (Homo sapiens)


name: CYP4F11 16-hydroxylates 3OH-PALM (Xenopus tropicalis)


name: H(+) + 2 H2O2 + hexadecanoate => CO2 + 3 H2O + pentadecanal


name: ganglioside GM2 (d18:1(4E)/18:0) + H2O <=> ganglioside GA2 (d18:1(4E)/18:0) + N-acetylneuraminate


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Sus scrofa)


name: an N-methylornithine lipid + S-adenosyl-L-methionine => an N,N-dimethylornithine lipid + H(+) + S-adenosyl-L-homocysteine


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Mus musculus)


name: CBL ubiquitinates FRS2 and FGFR3 (Canis familiaris)


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Canis familiaris)


name: [(1->2)-beta-D-mannosyl](n) + phosphate <=> [(1->2)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate


name: an acyl-CoA + H2O = a carboxylate + CoA + H(+)


name: Interaction of PECAM-1 and SHP-2 (Sus scrofa)


name: 2,3-bis-O-(geranylfarnesyl)-sn-glycerol 1-phosphate + diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-3-(O-farnesylgeranyl)glycerol 1-phosphate


name: a uridine in mRNA + S-adenosyl-L-methionine => a 5-methyluridine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Rattus norvegicus)


name: TRAF2,6 ubiquitinates NLRC5 (Bos taurus)


name: (2R)-3-phosphoglycerate + 2 H(+) + NADPH => D-glyceraldehyde 3-phosphate + H2O + NADP(+)


name: (+)-premalbrancheamide + 2 chloride + 2 FAD + 4 H(+) <=> (+)-malbrancheamide + 2 FADH2


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Mus musculus)


name: aculene D + L-prolyl-[peptidyl-carrier protein] = aculene B + holo-[peptidyl-carrier protein]


name: 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: 3'-phosphoadenylyl sulfate + 3beta-hydroxy-5-cholenate = 3beta-sulfo-5-cholenate + adenosine 3',5'-bisphosphate + H(+)


name: (S)-malyl N-acetyl-alpha-D-glucosaminide + H(+) + UDP => (S)-malate + UDP-N-acetyl-alpha-D-glucosamine


name: NADP(+) + prostaglandin E1 = 15-oxoprostaglandin E1 + H(+) + NADPH


name: 6-hydroxynicotinate + H2O + O2 => 2,6-dihydroxynicotinate + H2O2


name: MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) (Homo sapiens)


name: benzoyl-CoA + glycine <=> CoA + H(+) + N-benzoylglycine


name: (+)-artemisinic alcohol + O2 + reduced [NADPH--hemoprotein reductase] <=> (+)-artemisinic aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (3S)-hydroxytetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O


name: Interaction of PECAM-1 and SHIP (Canis familiaris)


name: Phosphorylated MOB1A proteins associate with LATS proteins (Caenorhabditis elegans)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: PARVA associates with Paxillin (Homo sapiens)


name: MARK4 binds ODF2 in the centriole (Bos taurus)


name: [thioredoxin]-disulfide + prostaglandin F2alpha => [thioredoxin]-dithiol + prostaglandin H2


name: dopamine + hexadecanoyl-CoA = CoA + H(+) + N-hexadecanoyl-dopamine


name: acetylsalicylate + L-seryl-[protein] <=> O-acetyl-L-seryl-[protein] + salicylate


name: a 3beta-hydroxy-Delta(5)-steroid + NAD(+) <=> a 3-oxo-Delta(5)-steroid + H(+) + NADH


name: Formation of RAD50:MRE11 complex (Sus scrofa)


name: 2 Fe(III)-[cytochrome cL] + methanol = 2 Fe(II)-[cytochrome cL] + formaldehyde + 2 H(+)


name: RTC completes synthesis of the minus strand genomic RNA complement (Homo sapiens)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Homo sapiens)


name: Vanin hydrolyses pantetheine to PanK, 2AET (Canis familiaris)


name: p-STAT1 dimer binds KPNA1 (Xenopus tropicalis)


name: (14S,15S)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate => (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O


name: FMNH2 + NADH + O2 + uracil <=> (Z)-3-ureidoacrylate + FMN + H(+) + H2O + NAD(+)


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Canis familiaris)


name: H2O + medicarpin <=> 4'-methoxyisoflavan-2',4,7-triol


name: AMP + an aromatic aldehyde + diphosphate + NADP(+) <=> an aromatic carboxylate + ATP + H(+) + NADPH


name: [(1->2)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate => [(1->2)-beta-D-glucosyl](n) + phosphate


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Canis familiaris)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Danio rerio)


name: XIAP monoubiquinates TLE (Drosophila melanogaster)


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1->4)-alpha-D-galacturonosyl](n) + n H(+) + n methanol


name: MTA2-NuRD complex deacetylates TP53 (Canis familiaris)


name: H(+) + S-adenosyl-L-homocysteine + sterigmatocystin => 6-demethylsterigmatocystin + S-adenosyl-L-methionine


name: ERBB4s80:STAT5A complex translocates to the nucleus (Homo sapiens)


name: Auto-ubiquitination of TRAF6 (Homo sapiens)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)


name: pyridoxamine + pyruvate => L-alanine + pyridoxal


name: SCD desaturates ST-CoA to OLE-CoA (Plasmodium falciparum)


name: lignostilbene alpha beta-dioxygenase activity


name: hydrogencarbonate + NH4(+) = carbamate + H(+) + H2O


name: Dissociation of CaM and CAMK2 autophosphorylation (Gallus gallus)


name: (1S,2R,4S)-neodihydrocarveol + NAD(+) => (1S,4S)-dihydrocarvone + H(+) + NADH


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Danio rerio)


name: BMP2 binds to the receptor complex (Drosophila melanogaster)


name: Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Drosophila melanogaster)


name: FRAT proteins bind GSK3beta (Canis familiaris)


name: Activated ATM phosphorylates DCLRE1C (Canis familiaris)


name: A + dihydrobisanhydrobacterioruberin = AH2 + bisanhydrobacterioruberin


name: ent-cassa-12,15-dien-2beta-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-cassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 2,5-diformylfuran + H2O2 => 5-hydroxymethylfurfural + O2


name: D-octopine + H2O + NAD(+) = H(+) + L-arginine + NADH + pyruvate


name: SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Caenorhabditis elegans)


name: 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NADP(+) => anthraniloyl-CoA + 2 H(+) + 2 NADPH + O2


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 18-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: DCC interaction with Ezrin (Xenopus tropicalis)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Sus scrofa)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Rattus norvegicus)


name: H2O + S-succinylglutathione => glutathione + H(+) + succinate


name: [cypemycin](1-18)-L-Cys-L-Leu-L-Val-L-Cys + A = AH2 + C(3,19),S(21)-[cypemycin](1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide + CO2 + hydrogen sulfide


name: "cypemycin cysteine dehydrogenase (decarboxylating)"


name: RHOA GAPs stimulate RHOA GTPase activity (Schizosaccharomyces pombe)


name: (1S,4S)-dihydrocarvone + H(+) + NADH => (1S,2R,4S)-neodihydrocarveol + NAD(+)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Schizosaccharomyces pombe)


name: ARSC hydrolyzes steroid sulfates (Homo sapiens)


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Xenopus tropicalis)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine <=> an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Gallus gallus)


name: acetate + L-ornithine => H2O + N(2)-acetyl-L-ornithine


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Caenorhabditis elegans)


name: Collagen type XXV ectomain shedding (Homo sapiens)


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-jasmololone <=> CoA + jasmolin I


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Mus musculus)


name: 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming)


name: MMACHC:cob(II)alamin binds MMADHC (Homo sapiens)


name: Rho-dependent protein serine/threonine kinase activity


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Dictyostelium discoideum)


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = corticosterone + H2O + 2 oxidized [adrenodoxin]


name: MLKL binds PDCD6IP and SDCBP (Homo sapiens)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Caenorhabditis elegans)


name: H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide = a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine


name: a ganglioside GQ1c (d18:1(4E)) + H2O = a ganglioside GT1c (d18:1(4E)) + N-acetylneuraminate


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Caenorhabditis elegans)


name: ALDH3A2-2 oxidizes pristanal to pristanate (Mus musculus)


name: CoA + ethyl acetate => acetyl-CoA + ethanol


name: 3-(2,4-dioxopentyl)-3,6,8,9-tetrahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2 <=> 3-(2,4-dioxopentyl)-2,3,6,8,9-pentahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+)


name: Formation of the 43S pre-initiation complex (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Homo sapiens)


name: RNA lariat debranching enzyme activator activity


name: Interaction of Tie2 with Ang1 (Rattus norvegicus)


name: 2 Na(+)(out) + phosphate(out) => 2 Na(+)(in) + phosphate(in)


name: a (2E,4Z)-dienoyl-CoA + H(+) + NADPH => a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)


name: (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + H(+) + NADPH


name: 10-deoxysarpagine + NADP(+) <=> H(+) + NADPH + vellosimine


name: ATP + D-ribose 5-phosphate + NH4(+) = 5-phospho-beta-D-ribosylamine + ADP + H(+) + phosphate


name: Kinesin-5 is a homotetramer (Drosophila melanogaster)


name: EP3 receptor can bind PGE2 (Drosophila melanogaster)


name: UGT8 transfers Gal from UDP-Gal to CERA (Mus musculus)


name: VKORC1 inhibitors binds VKORC1 dimer (Homo sapiens)


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Homo sapiens)


name: ADP + H(+) + N-acetyl-D-muramate 6-phosphate => ATP + N-acetyl-D-muramate


name: GBA3 hydrolyzes GlcCer (cytosol) (Drosophila melanogaster)


name: a globoside Gb4Cer + N-acetyl-alpha-D-galactosamine => a globoside IV3GalNAc-Gb4Cer + H2O


name: MRN complex binds shortened telomeres (Gallus gallus)


name: RAB1:GTP recruits GBF1 to the ERGIC (Rattus norvegicus)


name: RNA Polymerase II Promoter Opening: First Transition (Caenorhabditis elegans)


name: (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] <=> glyceollin III + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: ADK phosphorylates RBV (Schizosaccharomyces pombe)


name: Initial activation of proMMP1 (Drosophila melanogaster)


name: (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA + NADP(+)


name: Formation of lysyl-pyridinoline cross-links (Mus musculus)


name: dichlorochromopyrrolate + H(+) + 2 H2O + NH4(+) => 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2


name: RHOQ translocates to the Golgi-associated vesicle membranes (Schizosaccharomyces pombe)


name: heliamine + S-adenosyl-L-methionine = H(+) + N-methylheliamine + S-adenosyl-L-homocysteine


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Xenopus tropicalis)


name: 1alpha,25-dihydroxyvitamin D2 + H2O + 2 oxidized [adrenodoxin] => 25-hydroxyvitamin D2 + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: ZnT8 transports zinc into the Golgi apparatus (Bos taurus)


name: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene <=> 1,2,3,5-tetrahydroxybenzene + 1,3,5-trihydroxybenzene


name: RAD51 binds BRCA2 at resected DNA DSBs (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a 1-acyl-sn-glycero-3-phosphocholine


name: borneol + NAD(+) <=> camphor + H(+) + NADH


name: TGFBR2 phosphorylates TGFBR1 (Bos taurus)


name: 1,4-dihydroxy-2-naphthoate + all-trans-octaprenyl diphosphate + H(+) => 2-demethylmenaquinol-8 + CO2 + diphosphate


name: RNASEs bind bacterial LPS, PGN (Rattus norvegicus)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Sus scrofa)


name: Parkin transfers Ub to misfolded proteins (Plasmodium falciparum)


name: CYP3A4 can N-demethylate loperamide (Danio rerio)


name: RLBP1 binds atROL to form RLBP1:atROL (Danio rerio)


name: 7,8-dihydropteroate + H2O => 4-aminobenzoate + 6-hydroxymethyl-7,8-dihydropterin


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Caenorhabditis elegans)


name: (6S)-5,6,7,8-tetrahydrofolate(out) + ATP + H2O = (6S)-5,6,7,8-tetrahydrofolate(in) + ADP + H(+) + phosphate


name: Methylation of GMP-cap by RNA Methyltransferase (Canis familiaris)


name: Defective POMT1 does not transfer Man from Dol-P-Man to DAG1 (Homo sapiens)


name: NLRP3 activation by small molecules (Canis familiaris)


name: S1P hydrolyzes SREBP1A,1C,2 (Rattus norvegicus)


name: Active ARF recruits coatomer (Saccharomyces cerevisiae)


name: 1-hydroxy-5alpha-androstan-3,17-dione + A = 5alpha-androstan-1,3,17-trione + AH2


name: A + chloride + ethene + H(+) => AH2 + chloroethene


name: CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine (Xenopus tropicalis)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Drosophila melanogaster)


name: p-S363,S380,T573 RS6K translocates to the nucleus (Saccharomyces cerevisiae)


name: H2O + L-histidine + O2 => 3-(imidazol-5-yl)pyruvate + H2O2 + NH4(+)


name: GDIs block activation of RHOC (Bos taurus)


name: KMT2A (MLL) binds RUNX1 (Rattus norvegicus)


name: KSRP recruits RNA degradation activities (Rattus norvegicus)


name: 3-chloro-D-alanine = 2-aminoprop-2-enoate + chloride + H(+)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Canis familiaris)


name: 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine => 1-tetradecanoyl-sn-glycero-2,3-cyclic phosphate + ethanolamine


name: Degradation of multiubiquitinated Cdh1 (Gallus gallus)


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Canis familiaris)


name: CFTR binds components of the ERAD machinery for ubiquitination and degradation (Rattus norvegicus)


name: 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + trans-aconitate = CO2 + itaconate


name: abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase]


name: Phosphorylated AMPK binds AMP (Gallus gallus)


name: Formation of classic pathway C5 convertase (Canis familiaris)


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Canis familiaris)


name: ALK autophosphorylation  (Rattus norvegicus)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Caenorhabditis elegans)


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Rattus norvegicus)


name: (indol-3-yl)acetate + L-aspartate => (indol-3-yl)acetyl-L-aspartate + H2O


name: CDC42 translocates to the endoplasmic reticulum membrane (Saccharomyces cerevisiae)


name: Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (Sus scrofa)


name: allocryptopine + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-cis-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase]


name: DBI, ACBD7 bind MCFA-CoA and LCFA-CoA (Homo sapiens)


name: ERBB2 promotes PTK6 autophosphorylation (Rattus norvegicus)


name: HYAL1 hydrolyses Chondroitin chains (Canis familiaris)


name: ABCA4 mediates atRAL transport (Canis familiaris)


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Xenopus tropicalis)


name: FMO1:FAD N-oxidises TAM (Caenorhabditis elegans)


name: Fe(III)-{di[N-(2,3-dihydroxybenzoyl)-L-seryl]-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + H(+) => Fe(III)-C-5-deoxy-beta-D-glucosyl-enterobactin + H2O


name: (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine = 3-O-acetyl-4'-O-demethylpapaveroxine + H(+)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Caenorhabditis elegans)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Xenopus tropicalis)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Canis familiaris)


name: NAD+ synthase (glutamine-hydrolyzing) activity


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Xenopus tropicalis)


name: (2R,3S)-3-methylmalate + NAD(+) = 2-oxobutanoate + CO2 + NADH


name: CoA + jasmolin II => (1R,3R)-pyrethroyl-CoA + (Z,S)-jasmololone


name: Association of ADAM and B4GALT1 With ZP3 (Canis familiaris)


name: (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+) => D-ribulose 5-phosphate


name: 2-MAG is transacylated to DAG by PNPLA2/3 (Xenopus tropicalis)


name: a 2-acylphloroglucinol + dimethylallyl diphosphate <=> a 2-acyl-4-prenylphloroglucinol + diphosphate


name: AKT phosphorylates PHF20 (Rattus norvegicus)


name: SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP (Rattus norvegicus)


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Canis familiaris)


name: GSDMD (1-275) binds bacterial cardiolipin (Mus musculus)


name: 1D-myo-inositol 3-phosphate + a CDP-1,2-diacyl-sn-glycerol <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)


name: Dentin matrix protein 1 binds integrin alphaVbeta3 (Bos taurus)


name: Retrograde COPI vesicles bind kinesin and microtubules (Bos taurus)


name: p-4Y-SIRPA:CD47 binds GRB2-1 (Sus scrofa)


name: HLCS biotinylates PC:Mn2+ (Mus musculus)


name: IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Homo sapiens)


name: ATP + D-ribose(out) + H2O => ADP + D-ribose(in) + H(+) + phosphate


name: phosphoenolpyruvate carboxykinase (diphosphate) activity


name: 2 H(+) + jolkinol C + 2 NADH => 4,5,8-trihydroxycasbene + 2 NAD(+)


name: Active calmodulin binds CAMK2 (Sus scrofa)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecylglycerol = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol


name: SOCS5,(SOCS1) bind IL4RA (Canis familiaris)


name: H(+) + 2 L-arginine + 3 NADH + 4 O2 => 4 H2O + 2 L-citrulline + 3 NAD(+) + 2 nitric oxide


name: H(+) + NADH + O2 + vanillate <=> 3,4-dihydroxybenzoate + formaldehyde + H2O + NAD(+)


name: ALOX5 oxidises EPA to 5-HEPE (Danio rerio)


name: FABP5 dissociates from RXRA:PPARD:atRA (Homo sapiens)


name: aspulvinone E + O2 <=> (2Z)-2-[(3,4-dioxocyclohexa-1,5-dien-1-yl)methylidene]-4-(4-hydroxyphenyl)-5-oxo-2,5-dihydrofuran-3-olate + H2O


name: ATP + GTP <=> diphosphate + pppGp(2'-5')A


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Saccharomyces cerevisiae)


name: 3,4,5-trihydroxybenzoate(in) + H(+)(in) => 3,4,5-trihydroxybenzoate(out) + H(+)(out)


name: (17E)-cheilanthenediol => (2E,6E,10E,14E)-geranylfarnesol + H2O


name: a 3-oxo-Delta(1,4)-steroid + AH2 => A + a 3-oxo-Delta(4)-steroid


name: [cis-1,4-isoprene](n) + O2 <=> (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal + cis-1,4-isoprene(n-3)


name: 2-oxoglutarate + beta-alanine = 3-oxopropanoate + L-glutamate


name: 4-coumaroyl-CoA + shikimate => CoA + trans-4-coumaroylshikimate


name: RAP1A exchanges GDP for GTP (Canis familiaris)


name: 2-hydroxyethane-1-sulfonate + NAD(+) = H(+) + NADH + sulfoacetaldehyde


name: active transmembrane transporter activity


name: HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) (Bos taurus)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Caenorhabditis elegans)


name: VKORC1 inhibitors binds VKORC1 dimer (Canis familiaris)


name: HATs and coactivators are recruited to the CTSD gene (Canis familiaris)


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Bos taurus)


name: OGG1beta G12E does not translocate to mitochondria (Homo sapiens)


name: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH


name: (E)-caffeoyl-CoA + D-threo-isocitrate <=> 2-[(E)-caffeoyl]-D-threo-isocitrate(3-) + CoA


name: peroxisome membrane targeting sequence binding


name: 2 benzoyl-CoA + L-ornithine <=> 2 CoA + 2 H(+) + N(2),N(5)-dibenzoyl-L-ornithine


name: Activation of Calcineurin (Dictyostelium discoideum)


name: AKT1 E17K mutant phosphorylates RSK (Homo sapiens)


name: Crk's SH3 domain engages C3G (Sus scrofa)


name: a ribonucleoside 5'-triphosphate + formate + H(+) = a 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O


name: Disassociation of Telomerase RNP and the Chromosome End (Rattus norvegicus)


name: Na(+)(out) + propanoate(out) <=> Na(+)(in) + propanoate(in)


name: 5-fluorocytidine 5'-phosphate + ADP + H(+) => 5-fluorocytidine + ATP


name: Hh processing variants are translocated to the cytosol in a VCP-dependent manner (Homo sapiens)


name: AMP + D-alanyl-[D-alanyl-carrier protein] + diphosphate => ATP + D-alanine + holo-[D-alanyl-carrier protein]


name: Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Bos taurus)


name: IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Danio rerio)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: p-S54-PDE4B hydrolyses cAMP (Sus scrofa)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Mus musculus)


name: ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Homo sapiens)


name: 26Sproteasome degrades K48polyUb-NIK (Canis familiaris)


name: [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = yaequinolone C


name: p62 is recruited and forms a complex with TRAF6 (Xenopus tropicalis)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 26-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RUNX1:CBFB binds CREBBP (Drosophila melanogaster)


name: PEBP1 binds activated RAF1 (Homo sapiens)


name: Trafficking of nonameric complex in the endocytic pathway (Sus scrofa)


name: cAMP degradation by Phosphodiesterases (Drosophila melanogaster)


name: Tyrosine is monoiodinated (Caenorhabditis elegans)


name: H2O + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein] <=> 4-hydroxy-2-oxobutanal + L-lysyl-[protein] + phosphate


name: a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: 2'-N-acetylparomamine + H2O = acetate + paromamine


name: 4-chlorophenylacetate + NADH + O2 => 3,4-dihydroxyphenylacetate + chloride + NAD(+)


name: thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] (Xenopus tropicalis)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Sus scrofa)


name: [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + H2O = [CysO sulfur-carrier protein]-C-terminal Gly-Gly + H(+) + L-cysteine


name: "[CysO sulfur-carrier protein]-S-L-cysteine hydrolase"


name: 2-hydroxyhexacosanoyl-CoA + sphinganine => CoA + H(+) + N-(2-hydroxyhexacosanoyl)-sphinganine


name: ATP + L-isoleucine + tRNA(Ile) => AMP + diphosphate + L-isoleucyl-tRNA(Ile)


name: 6 H(+) + 2 hydrogen sulfide + 2 sulfite => 4 H2O + O2 + 4 sulfur


name: NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = H(+) + NADH + UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose


name: Association of procollagen type V (Sus scrofa)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Xenopus tropicalis)


name: PGLYRP3,4 binds bacterial peptidoglycan (Sus scrofa)


name: 2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Mus musculus)


name: adenosine 5'-phosphoramidate + 2 H(+) + sulfate => adenosine 5'-phosphosulfate + NH4(+)


name: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid (Canis familiaris)


name: 6-amino-2-oxohexanoate => Delta(1)-piperideine-2-carboxylate + H2O


name: 26-desgluco-avenacoside B + D-glucose => avenacoside B + H2O


name: 10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Dictyostelium discoideum)


name: CALCA(83-119) binds CALCA antibodies (Mus musculus)


name: FA anion flip-flops to the opposite surface (Caenorhabditis elegans)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: H2O + N-eicosanoyl-sphing-4-enine => eicosanoate + sphing-4-enine


name: 2'-deoxycytidine + ATP => ADP + dCMP + H(+)


name: NADPH transfers electrons to FDXR (Canis familiaris)


name: G alpha (q) in G (q):RGS complex is inactivated (Schizosaccharomyces pombe)


name: 3 (R)-methylmalonyl-CoA + 9 H(+) + long-chain fatty acyl-[mycocerosate synthase] + 6 NADPH = 3 CO2 + 3 CoA + 3 H2O + 6 NADP(+) + trimethylated-mycocerosoyl-[mycocerosate synthase]


name: LC3:ATG7 dimer binds ATG3 (Mus musculus)


name: The PACAP receptor binds PACAP (Rattus norvegicus)


name: Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants (Homo sapiens)


name: benzaldehyde + H2O + NAD(+) <=> benzoate + 2 H(+) + NADH


name: JNK phosphorylates BIM, BAD and other targets (Canis familiaris)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Mus musculus)


name: ABHD14B hydrolyses PNPB (Caenorhabditis elegans)


name: CYP39A1 7-hydroxylates 24OH-CHOL (Mus musculus)


name: GUCA binds Ca2+ to form GUCA:Ca2+ (Mus musculus)


name: an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: CHRM1,3,5 bind acetylcholine (Gallus gallus)


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Danio rerio)


name: D-glucose(out) + 2 Na(+)(out) <=> D-glucose(in) + 2 Na(+)(in)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Rattus norvegicus)


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Danio rerio)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Plasmodium falciparum)


name: DVL2 is phosphorylated after WNT5A binding to FZD (Homo sapiens)


name: PRDM1 represses TP53 expression (Homo sapiens)


name: (2-hydroxyphenyl)acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-phenylacetate + O2 + reduced [NADPH--hemoprotein reductase]


name: apo-[methylmalonyl-CoA:pyruvate carboxytransferase] + ATP + biotin = AMP + diphosphate + H(+) + holo-[methylmalonyl-CoA:pyruvate carboxytransferase]


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (6E,10E)-geranyllinalool + diphosphate


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-O-hexadecyl-sn-glycero-3-phosphocholine = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Caenorhabditis elegans)


name: a ubiquinol + nitrate <=> a ubiquinone + H2O + nitrite


name: PNPLA6 hydrolyzes LysoPtdCho (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an N-acyl-sphingoid base + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose => a ganglioside GM3 + H2O


name: Expression of CXCR4 in primordial germ cells (Homo sapiens)


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Xenopus tropicalis)


name: bilirubin IXalpha + NAD(+) => biliverdin IXalpha + H(+) + NADH


name: adenosine(in) + H(+)(in) <=> adenosine(out) + H(+)(out)


name: MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)


name: HuR binds the CRM1 nuclear export machinery (Bos taurus)


name: "7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase"


name: L-tyrosyl-[protein] + 2 O2 => H(+) + H2O2 + L-topaquinyl-[protein]


name: beta-nicotinamide D-ribonucleotide + H2O => D-ribose 5-phosphate + H(+) + nicotinamide


name: 4-hydoxytryptamine 4-phosphate + S-adenosyl-L-methionine <=> 4-hydroxy-N-methyltryptamine 4-phosphate + H(+) + S-adenosyl-L-homocysteine


name: (13Z)-docosenoyl-CoA + sphing-4-enine => CoA + H(+) + N-(13Z-docosenoyl)-sphing-4-enine


name: Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Canis familiaris)


name: (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + NADP(+) => (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA + H(+) + NADPH


name: Ag(+)(in) + ATP + H2O <=> ADP + Ag(+)(out) + H(+) + phosphate


name: CBL ubiquitinates Sprouty (Caenorhabditis elegans)


name: RHOV binds effectors at the plasma membrane (Gallus gallus)


name: Activation of TWIK-related K+ channel (TREK) (Canis familiaris)


name: GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 (Saccharomyces cerevisiae)


name: 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O <=> (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: Formation of ORC(2-5) complex (Schizosaccharomyces pombe)


name: ADRM1:26S proteaseome binds USP14 (Drosophila melanogaster)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Caenorhabditis elegans)


name: ADP-D-ribose + L-cysteinyl-[protein] => H2O + S-(ADP-D-ribosyl)-L-cysteinyl-[protein]


name: Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Rattus norvegicus)


name: 2-oxobutanoate + L-selenocysteine + NH4(+) => H2O + L-selenocystathionine


name: p-2S-SMAD2,3:SMAD4, CTNNB1, and TBPL2 bind FOXH1:SMAD3:EOMES gene (Homo sapiens)


name: p-PKR dimer phosphorylates DHX9 (Canis familiaris)


name: Keratin type I binds keratin type II (Bos taurus)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 chloride + 2 FADH2 + 2 O2 => (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 FAD + 4 H2O


name: DPH6 ligates ammonium to diphthine-EEF2 (Rattus norvegicus)


name: Nectin-1:PVRL3 trans heterodimer formation (Sus scrofa)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Drosophila melanogaster)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Mus musculus)


name: dimethylallyl diphosphate + umbelliferone = demethylsuberosin + diphosphate


name: laricitrin + S-adenosyl-L-methionine => 3,3'-O-dimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: ATM phosphorylates NBN (Dictyostelium discoideum)


name: sulfate is activated to APS (Mycobacterium tuberculosis)


name: Myoglobin:oxygen dissociates (Homo sapiens)


name: Phosphorylation of Plexin-A (Homo sapiens)


name: 3-oxosphinganine + a fatty acyl-CoA = CoA + H(+) + N-acyl-3-oxosphinganine


name: Cleavage of Procaspase‑9 to caspase‑9 (Drosophila melanogaster)


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O => 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: SUMOylation of RAD52 with SUMO1 (Sus scrofa)


name: NICD1 binds the NFE2L2 promoter (Homo sapiens)


name: ST3GAL2,3 transfer Neu5Ac to gangliosides (Canis familiaris)


name: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Drosophila melanogaster)


name: methyl tertiary butyl ether 3-monooxygenase activity


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Sus scrofa)


name: 2,2-dialkylglycine decarboxylase (pyruvate) activity


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-choline => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: IRAK4 is activated by autophosphorylation (Bos taurus)


name: aryl-alcohol dehydrogenase (NADP+) activity


name: H(+) + S-adenosyl-L-methionine => CO2 + S-adenosyl 3-(methylsulfanyl)propylamine


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)


name: a 7beta-hydroxysteroid + NADP(+) => a 7-oxosteroid + H(+) + NADPH


name: Recruitment of Rad17-RFC complex to DNA (Schizosaccharomyces pombe)


name: LDHAL6B reduces PYR to LACT (Danio rerio)


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Drosophila melanogaster)


name: SLC29A1 transports RBV from cytosol to extracellular region (Canis familiaris)


name: PIAS1,3 SUMOylate ESR1 with SUMO1 (Gallus gallus)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Bos taurus)


name: ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Caenorhabditis elegans)


name: (20R,22R)-20,22-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin] => (22R)-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Bos taurus)


name: alpha-D-glucose + D-maltohexaose => D-maltoheptaose + H2O


name: "Activator" RAF:YWHAB dimer binds RAS:GTP (Caenorhabditis elegans)


name: Activated FGFR4:p-FRS binds GRB2:SOS1 (Xenopus tropicalis)


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Xenopus tropicalis)


name: dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid = desmethyldescarbamoylnovobiocin + dTDP + H(+)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)


name: malonyl-CoA + quercetin 3-O-beta-D-glucoside => CoA + quercetin 3-O-(6-O-malonyl-beta-D-glucoside)


name: 3-demethylubiquinol-7 + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + ubiquinol-7


name: 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O <=> 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + CoA + H(+)


name: H2O + O(6)-methyl-dGTP = diphosphate + H(+) + O(6)-methyl-dGMP


name: ATP7A transports cytosolic Cu2+ to extracellular region (Rattus norvegicus)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Homo sapiens)


name: SLC16A10-mediated uptake of aromatic amino acids (Sus scrofa)


name: an aldehyde + H2O + O2 <=> a carboxylate + H(+) + H2O2


name: CCNA1 gene expression is stimulated by E2F1 (Homo sapiens)


name: MEOS oxidizes ethanol to acetaldehyde (Caenorhabditis elegans)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 <=> (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate


name: CMP + phosphate = alpha-D-ribose 1,5-bisphosphate + cytosine


name: MMAA:MUT binds AdoCbl (Rattus norvegicus)


name: (2R,3R)-dihydrokaempferol + O2 + reduced [NADPH--hemoprotein reductase] = (2R,3R)-dihydroquercetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate <=> 15-cis-phytoene + 2 diphosphate


name: PCK1 phosphorylates OA to yield PEP (Canis familiaris)


name: GRIK3 homomer binds glutamate (Mus musculus)


name: 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine


name: RAC2 GDIs block activation of RAC2 (Gallus gallus)


name: 3-(carbamoylamino)-2-methylpropanoate + H(+) => 5,6-dihydrothymine + H2O


name: a 27-hydroxysterol + UDP-alpha-D-glucose <=> a sterol 27-beta-D-glucoside + H(+) + UDP


name: (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate => (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2


name: RAC3 GDIs block activation of RAC3 (Drosophila melanogaster)


name: Furin cleaves pro-protein C to protein C (Mus musculus)


name: CYTH proteins stimulate ARF1 GTPase activity (Schizosaccharomyces pombe)


name: Mg-protoporphyrin IX + S-adenosyl-L-methionine <=> Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine


name: alpha-L-arabinopyanose + NADP(+) = H(+) + L-arabinono-1,4-lactone + NADPH


name: ATP + citrate + CoA => acetyl-CoA + ADP + oxaloacetate + phosphate


name: 7,8-dihydroneopterin 3'-phosphate + diphosphate + H(+) => 7,8-dihydroneopterin 3'-triphosphate + H2O


name: H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate => 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate


name: Association of procollagen type XVII (Bos taurus)


name: TP53 stimulates BCL2L14 gene expression (Homo sapiens)


name: a long-chain fatty acyl-CoA + AMP + diphosphate => a long-chain fatty acid + ATP + CoA


name: (6R)-10-formyltetrahydrofolate + H2O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH


name: S1PR1 binds S1PR1 agonists (Xenopus tropicalis)


name: GAB1 recruits CRK,CRKL to MET (Sus scrofa)


name: Autophosphorylation of insulin receptor (Xenopus tropicalis)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Homo sapiens)


name: Elastin degradation by MMP14 (Rattus norvegicus)


name: (1S,8aR)-delta-cadinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: BSK is phosphorylated and activated by phosphorylated HEP kinase (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate <=> alpha-longipinene + diphosphate


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Sus scrofa)


name: 3'-phosphoadenylyl sulfate + glycochenodeoxycholate <=> adenosine 3',5'-bisphosphate + glycochenodeoxycholate 7-sulfate + H(+)


name: SCF(SKP2) complex binds RUNX2 (Homo sapiens)


name: cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine => 5-methylcytidine(4447) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Danio rerio)


name: Beta-defensins bind microbial membranes causing disruption (Gallus gallus)


name: Defective OGG1 mutants do not excise 8-oxoguanine (Homo sapiens)


name: OCT3 mediates renal uptake of organic cations (Danio rerio)


name: (2E)-tetradecenoyl-CoA + FADH2 => FAD + H(+) + tetradecanoyl-CoA


name: PGRMC2 binds Hemes (Saccharomyces cerevisiae)


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADPH


name: ATP + D-ribose 5-phosphate + NH4(+) => 5-phospho-beta-D-ribosylamine + ADP + H(+) + phosphate


name: 1,2-dihydro-alpha-santonin + NADP(+) => alpha-santonin + H(+) + NADPH


name: Protesomal degradation of K48polyUb-TRAF3 (Homo sapiens)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Schizosaccharomyces pombe)


name: (indol-3-yl)acetyl-L-aspartate + H2O => (indol-3-yl)acetate + L-aspartate


name: PI3K associates with phosphorylated GAB2 (Gallus gallus)


name: 3-[(2E,4E,8S,10E,12Z)-4,8-dimethyltetradeca-2,4,10,12-tetraenoyl]-4-hydroxy-5-(4-hydroxyphenyl)-1,2-dihydropyridin-2-one + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (3E,5S)-3-[(2E,4E,8S,10E,12Z)-1-hydroxy-4,8-dimethyltetradeca-2,4,10,12-tetraen-1-ylidene]-5-[(4-hydroxyphenyl)methyl]pyrrolidine-2,4-dione + O2 + reduced [NADPH--hemoprotein reductase]


name: (3R)-3-{[carboxy(hydroxy)methyl]amino}butanoate + CO2 + succinate => (3R)-3-[(carboxymethyl)amino]butanoate + 2-oxoglutarate + O2


name: H2O + polyneuridine aldehyde <=> 16-epivellosimine + CO2 + methanol


name: Expression of PLIN1 regulated by NR1H2 or NR1H3 (Homo sapiens)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Danio rerio)


name: GDP-beta-L-fucose + L-seryl-[EGF-like domain protein] <=> 3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + GDP + H(+)


name: CHSY1 transfers GlcA to chondroitin (Canis familiaris)


name: 4-coumaroyl-CoA + S-adenosyl-L-methionine => CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-ethanolamine <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Rattus norvegicus)


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Caenorhabditis elegans)


name: Binding of NEP/NS2 to vRNP:M1 (Homo sapiens)


name: Inactivation of Rho-GTP by p190RhoGAP (Xenopus tropicalis)


name: H(+) + hexadecanoate + sn-glycerol 3-phosphocholine => 2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Sus scrofa)


name: ASIC3 channel blockers bind ASIC3 trimer (Drosophila melanogaster)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Mus musculus)


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Sus scrofa)


name: 3-hydroxypyruvate + H(+) + NADH + NH4(+) => H2O + L-serine + NAD(+)


name: an N(2)-(ADP-L-ribosyl)-2'-deoxyguanosine in DNA + H(+) + nicotinamide => a 2'-deoxyguanosine in DNA + NAD(+)


name: 5-O-beta-D-mycaminosyltylonolide + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 20-oxo-5-O-beta-D-mycaminosyltylonolide + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: p-Y694-STAT5A, p-STAT5B dimerizes (Bos taurus)


name: glandicoline B + S-adenosyl-L-methionine => H(+) + meleagrin + S-adenosyl-L-homocysteine


name: (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 AH2 <=> (8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 A + 2 H2O


name: BTNL2 binds activated T cells surface (Rattus norvegicus)


name: Guanine + H2O => Xanthine + NH4+ (Danio rerio)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Homo sapiens)


name: Formation of Cyclin A:Cdk2 complexes (Schizosaccharomyces pombe)


name: Gq activation by TP receptor (Xenopus tropicalis)


name: Binding of TFIIIA To type 1 Promoter (Rattus norvegicus)


name: an aromatic L-alpha-amino acid + glyoxylate = an aromatic oxo-acid + glycine


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Homo sapiens)


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate => 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + 2-oxoglutarate + H(+) + H2O


name: AMPK phosphorylates PPARGC1A (Homo sapiens)


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Mus musculus)


name: an N-acylethanolamine + H2O => a fatty acid + ethanolamine


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Mus musculus)


name: 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H(+) + UDP => 2',3,4,4',6'-pentahydroxychalcone + UDP-alpha-D-glucose


name: PSMD14 cleaves K63-linked ubiquitin (Homo sapiens)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Bos taurus)


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Dictyostelium discoideum)


name: holo-[peptidyl-carrier protein] + L-cysteinyl-5'-AMP = AMP + H(+) + L-cysteinyl-[peptidyl-carrier protein]


name: Activated FGFR2 binds FRS2 (Rattus norvegicus)


name: CYP21A2 21-hydroxylates PROG (Homo sapiens)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Sus scrofa)


name: 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Xenopus tropicalis)


name: (E)-non-2-enal + H(+) + NADPH => (E)-non-2-en-1-ol + NADP(+)


name: Phosphorylation of PLCgamma by PDGFR (Sus scrofa)


name: Kinesin-5 is a homotetramer (Bos taurus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Plasmodium falciparum)


name: ATP + L-glutamate + L-glutamyl-[beta-tubulin] <=> ADP + gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + H(+) + phosphate


name: (9Z,12Z,15Z)-octadecatrienoate + O2 = (13R)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: LETM1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) (Homo sapiens)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: 16alpha,17alpha-dihydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 6beta,16alpha,17alpha-trihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PITPNM1,2,3 exchange PI for PA (Saccharomyces cerevisiae)


name: 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 2-heptanoyl-sn-glycero-3-phosphocholine <=> 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + hexanoyl-sn-glycero-3-phosphoethanolamine


name: H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] => N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate


name: AFXBO translocates from cytosol to nucleoplasm (Homo sapiens)


name: aspulvinone H + 2 diphosphate => aspulvinone E + 2 dimethylallyl diphosphate


name: p-Y-STATs dimerize (Dictyostelium discoideum)


name: NADP(+) + zymosterol => H(+) + NADPH + zymosterone


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Bos taurus)


name: Parenchymal atROL translocates to HSCs (Gallus gallus)


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Gallus gallus)


name: UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Xenopus tropicalis)


name: 2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2'-hydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: Inactive G alpha (q) reassociates with G beta:gamma (Sus scrofa)


name: RNF20:RNF40 monoubiquitinates Histone H2B (Bos taurus)


name: PLK1 phosphorylates GORASP1 (Xenopus tropicalis)


name: CYP4F12 18-hydroxylates ARA (Sus scrofa)


name: alpha-D-mannose derivative + UDP-alpha-D-glucose <=> 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H(+) + UMP


name: 4-O-methylrhodomycin D + H2O => 10-carboxy-13-deoxydaunorubicin + H(+) + methanol


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Sus scrofa)


name: 5-aminopentanoate + acetate => 5-acetamidopentanoate + H2O


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Drosophila melanogaster)


name: glutathione-dependent sulfide quinone oxidoreductase activity


name: Insertion of MHC II:Ii complex in to the plasma membrane (Homo sapiens)


name: PNPLA6 hydrolyzes LysoPtdCho (Homo sapiens)


name: EPS15 and HGS bind ubiquitinated MET (Homo sapiens)


name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region (Mus musculus)


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)


name: CoA + H(+) + N-octadecanoylglycine => glycine + octadecanoyl-CoA


name: B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Danio rerio)


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Sus scrofa)


name: gramine + H(+) + S-adenosyl-L-homocysteine => (1H-indol-3-yl)-N-methylmethanamine + S-adenosyl-L-methionine


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)


name: a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: SUMOylation of HDAC1 with SUMO1 (Homo sapiens)


name: RHOA:GTP binds RHPN1 or RHPN2 (Canis familiaris)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Gallus gallus)


name: Loading of antigen peptide onto MHC class I molecule (Homo sapiens)


name: PP2A dephosphorylates BANF1 (Bos taurus)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Danio rerio)


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Drosophila melanogaster)


name: SLCO2B1 has a narrow substrate specificity (Caenorhabditis elegans)


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + NH4(+) = beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + phosphate


name: ATP + D-galactofuranose(out) + H2O => ADP + D-galactofuranose(in) + H(+) + phosphate


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Caenorhabditis elegans)


name: ATP + L-glutamyl-tRNA(Gln) => 5-phosphooxy-L-glutamyl-tRNA(Gln) + ADP


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)


name: 2xTRAP hydrolyzes FMN to RIB (Rattus norvegicus)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Drosophila melanogaster)


name: H2O + monoglucosyl-enterobactin = [N-(2,3-dihydroxybenzoyl)-L-seryl]2-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine + H(+)


name: Cho is phosphorylated to PCho by CHK dimer (Saccharomyces cerevisiae)


name: HCO3- transport through ion channel (Bos taurus)


name: Association of LBP with bacterial LPS (Gallus gallus)


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Caenorhabditis elegans)


name: a carboxylate + aniline + H(+) => an anilide + H2O


name: beta-D-fructose 6-phosphate + phosphate => beta-D-fructose 2,6-bisphosphate + H2O


name: (2R,3E)-phycocyanobilin + apo-L-cysteinyl(155)-[C-phycocyanin beta-subunit] => phycocyanobilin-L-cysteinyl(155)-[C-phycocyanin beta-subunit]


name: 2-oxoglutarate + a methylated nucleobase within DNA + O2 => a nucleobase within DNA + CO2 + formaldehyde + succinate


name: GNRHR binds chemical antagonists (Homo sapiens)


name: misfolded CFTR is degraded by the 26S proteasome (Danio rerio)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin] => 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: Keratin filament formation (Gallus gallus)


name: erinacol + O2 + reduced [NADPH--hemoprotein reductase] <=> cyathadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Rattus norvegicus)


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Drosophila melanogaster)


name: nsp3 binds to PLpro inhibitors (Homo sapiens)


name: NOX2 generates superoxide anion from oxygen (Rattus norvegicus)


name: SALMs1-3 bind each other in cis interactions (Mus musculus)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Danio rerio)


name: Formation of pre-mRNPs (Rattus norvegicus)


name: acetyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-acetyl-4'-phosphopantetheine


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: ALDHs oxidise atRAL to atRA (Rattus norvegicus)


name: a dolichyl beta-D-glucosyl phosphate + H2O => a dolichyl phosphate + D-glucose + H(+)


name: α2-agonists bind ADRA2A,B,C (Caenorhabditis elegans)


name: Packaging of antigenomic RNA of human respiratory syncytial virus (Homo sapiens)


name: PRMT1 methylates ESRs (Xenopus tropicalis)


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Canis familiaris)


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Bos taurus)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)


name: gamma-tocopherol + H(+) + NADPH + O2 => 13-hydroxy-gamma-tocopherol + H2O + NADP(+)


name: Phosphorylation of YAP by LATS2 (Danio rerio)


name: NADP(+) + trypanothione = H(+) + NADPH + trypanothione disulfide


name: TPI1 isomerizes GA3P to DHAP (Saccharomyces cerevisiae)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: ATP + H(+) + L-alanine <=> diphosphate + L-alanyl-5'-AMP


name: 3-phosphonopyruvate + H(+) <=> CO2 + phosphonoacetaldehyde


name: 1-(11Z-eicosenoyl)-glycerol + H2O <=> (11Z)-eicosenoate + glycerol + H(+)


name: an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an N-acylsphing-14Z-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 5 A + beta-staphylobilin + Fe(2+) + formaldehyde + 4 H2O => 5 AH2 + 2 H(+) + heme b + 4 O2


name: Dephosphorylation of inactive SRC by PTPB1 (Canis familiaris)


name: a cytidine in tRNA + S-adenosyl-L-methionine = a 5-methylcytidine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: AUF1:mRNA complex is destroyed (Bos taurus)


name: 3a localizes to the cell membrane (Homo sapiens)


name: SUMOylation of DDX5 with SUMO1 (Mus musculus)


name: botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol (Homo sapiens)


name: (S)-2-hydroxyglutarate + O2 <=> 2-oxoglutarate + H2O2


name: a 2-oxocarboxylate + L-ornithine <=> an L-alpha-amino acid + L-glutamate 5-semialdehyde


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Danio rerio)


name: ERKs are inactivated by protein phosphatase 2A (Bos taurus)


name: EPHAs bind EFNAs (Drosophila melanogaster)


name: L-leucine(out) + L-methionine(in) => L-leucine(in) + L-methionine(out)


name: O2 + reduced [NADPH--hemoprotein reductase] + taxusin = 7beta-hydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Sus scrofa)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Saccharomyces cerevisiae)


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Danio rerio)


name: Proteasome-mediated degradation of PolyUb-FBXL7 (Bos taurus)


name: glycochenodeoxycholate + NADP(+) => 7-oxoglycolithocholate + H(+) + NADPH


name: Association of procollagen type XVI (Mus musculus)


name: SLC6A3 binds DRIs (Caenorhabditis elegans)


name: CFHR dimers bind C3b (Rattus norvegicus)


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Drosophila melanogaster)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Homo sapiens)


name: guanosine(out) + Na(+)(out) = guanosine(in) + Na(+)(in)


name: ARFRP1 recruits ARL1 to the TGN (Homo sapiens)


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Saccharomyces cerevisiae)


name: PP2A mediated localization of RB1 protein in chromatin (Dictyostelium discoideum)


name: 2'-deoxycytidine + H(+) + H2O <=> 2'-deoxyuridine + NH4(+)


name: Prolactin receptor ligands bind the prolactin receptor (Homo sapiens)


name: mycothiol-dependent formaldehyde dehydrogenase activity


name: Interleukin-23 binds interleukin-23 receptor (Rattus norvegicus)


name: Opioid dissociates from MOR (Xenopus tropicalis)


name: 2,3-epoxyphylloquinone + 4-carboxy-L-glutamyl-[protein] + H(+) + H2O => CO2 + L-glutamyl-[protein] + O2 + phylloquinol


name: Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)


name: [(2E,6E,10E)-geranylgeranyl]-L-cysteine + H2O + O2 = (2E,6E,10E)-geranylgeranial + H2O2 + L-cysteine


name: a pyrimidine ribonucleoside 5'-phosphate + H2O <=> a pyrimidine nucleobase + D-ribose 5-phosphate


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + koraiol


name: H2O + L-aspartate + NADP(+) <=> H(+) + NADPH + NH4(+) + oxaloacetate


name: acetyl-CoA + D-tryptophan <=> CoA + H(+) + N-acetyl-D-tryptophan


name: Profilin:G-actin binds MKL1 (Bos taurus)


name: SULT1A1 dimer sulfonates NHABP (Canis familiaris)


name: PEBP1 binds activated RAF1 (Plasmodium falciparum)


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Caenorhabditis elegans)


name: Formation of dsRNA structure by looping  (Homo sapiens)


name: RAC2 binds effectors at the mitochondrial outer membrane (Rattus norvegicus)


name: Phosphorylated MAPKs phosphorylate ATF-2 (Mus musculus)


name: (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O => (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + chloride + FADH2 + O2


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Dictyostelium discoideum)


name: acetylacetone + O2 => acetate + H(+) + methylglyoxal


name: apo-Transferrin dissociates from the receptor complex (Mus musculus)


name: CBL autoubiquitinates (Rattus norvegicus)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Homo sapiens)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Rattus norvegicus)


name: menaquinone-8 + sn-glycerol 3-phosphate => dihydroxyacetone phosphate + menaquinol-8


name: 3-sulfinopropanoyl-CoA + H2O = H(+) + propanoyl-CoA + sulfite


name: ATP + coproporphyrin III(in) + H2O => ADP + coproporphyrin III(out) + H(+) + phosphate


name: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 => 2 vanillin


name: glyoxylate(in) + sulfate(out) => glyoxylate(out) + sulfate(in)


name: 5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity


name: ROS oxidize thioredoxin (Caenorhabditis elegans)


name: H(+) + oxidized [electron-transfer flavoprotein] + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Caenorhabditis elegans)


name: 3'-phosphoadenylyl sulfate + coelenterazine h <=> adenosine 3',5'-bisphosphate + H(+) + luciferyl sulfate


name: a cardiolipin + ethanolamine => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Drosophila melanogaster)


name: A + ethylbenzene + H2O => (S)-1-phenylethanol + AH2


name: [DsbA protein]-disulfide + [protein]-dithiol => [DsbA protein]-dithiol + [protein]-disulfide


name: (E)-sinapyl alcohol + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol + H(+) + UDP


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Xenopus tropicalis)


name: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Bos taurus)


name: NMT1/2 transfer MYS to GNAT1 (Homo sapiens)


name: beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + H(+) + UDP => beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP-alpha-D-galactofuranose


name: guanosine(1405) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(1405) in 16S rRNA + S-adenosyl-L-homocysteine


name: CQ, HCQ are protonated to CQ2+, HCQ2+ (Homo sapiens)


name: H2O + N-(acetyl)-sphing-4-enine => acetate + sphing-4-enine


name: Phosphorylated SHC1 recruits SHIP (Rattus norvegicus)


name: GPR143 binds L-Dopa (Xenopus tropicalis)


name: IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Homo sapiens)


name: RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Bos taurus)


name: Hv1 Mediated H+ Permeability (Danio rerio)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Rattus norvegicus)


name: PIAS1 SUMOylates SP3 with SUMO2 (Drosophila melanogaster)


name: CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA


name: 3,3',5-triiodo-L-thyronine(in) + L-tyrosine(out) => 3,3',5-triiodo-L-thyronine(out) + L-tyrosine(in)


name: (6R)-10-formyltetrahydrofolate + GDP-alpha-D-perosamine <=> (6S)-5,6,7,8-tetrahydrofolate + GDP-N-formyl-alpha-D-perosamine + H(+)


name: Trimming of peptides by IRAP in endocytic vesicles (Bos taurus)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Canis familiaris)


name: 3alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone


name: CO2 + gibberellin A44 + succinate => 2-oxoglutarate + gibberellin A53 + O2


name: AMP + H2O => IMP + NH4+ (AMPD) (Danio rerio)


name: acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) <=> CO + CoA + methyl-Co(III)-[corrinoid Fe-S protein]


name: p-S256-Aquaporin-2 passively transports water into cell (Homo sapiens)


name: H2O + prostaglandin F2alpha-CoA <=> CoA + H(+) + prostaglandin F2alpha


name: FABP5:atRA translocates from cytosol to nucleoplasm (Bos taurus)


name: Syndecans 1, 2 & 4 bind VTN (Mus musculus)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O => 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: hydrogen cyanide + thiosulfate <=> 2 H(+) + sulfite + thiocyanate


name: (2E)-13-methyltetradecenoyl-CoA + H2O => 3-hydroxyisopentadecanoyl-CoA


name: CoA + ethyl benzoate => benzoyl-CoA + ethanol


name: active monoatomic ion transmembrane transporter activity


name: dimethylallyl diphosphate + neoechinulin B = diphosphate + isoechinulin B


name: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Sus scrofa)


name: (E)-coniferaldehyde + UDP-alpha-D-glucose <=> 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + H(+) + UDP


name: NME1,2 hexamers phosphorylate RBV-DP (Danio rerio)


name: L-quinate + NADP(+) <=> 3-dehydroquinate + H(+) + NADPH


name: a ribonucleoside 5'-triphosphate + H2O => a ribonucleoside 5'-diphosphate + H(+) + phosphate


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Sus scrofa)


name: L-glutamine(in) + L-serine(out) + Na(+)(in) => L-glutamine(out) + L-serine(in) + Na(+)(out)


name: Detection of damage during initiation of DNA synthesis in S-phase (Canis familiaris)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Rattus norvegicus)


name: CoA + H(+) + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine


name: 2-acyl LPG is acylated to PG by LPGAT (Plasmodium falciparum)


name: 16-hydroxyhexadecanoate + NAD(+) <=> 16-oxohexadecanoate + H(+) + NADH


name: HSP90AA1 binds p-6Y-VEGFR2 (Rattus norvegicus)


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Sus scrofa)


name: a fatty acyl-CoA + sphinga-(4E,8E)-dienine = an N-acyl-sphinga-4,8-dienine + CoA + H(+)


name: Factor I inactivates MCP/CR1-bound C4b/C3b (Gallus gallus)


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Mus musculus)


name: CARKD dehydrates S-NAD(P)HX to NADPH (Plasmodium falciparum)


name: LARG activation by G alpha 12/13 (Xenopus tropicalis)


name: pyruvate + UTP <=> H(+) + phosphoenolpyruvate + UDP


name: NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)


name: eicosanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-nonadecylpyran-2-one + 2 CO2 + 3 CoA


name: ERCC8 (CSA) binds stalled RNA Pol II (Sus scrofa)


name: prostaglandin F2alpha(out) => prostaglandin F2alpha(in)


name: Cleavage of thymine by MBD4 glycosylase (Xenopus tropicalis)


name: cholesterol + PAPS => cholesterol sulfate + PAP (Drosophila melanogaster)


name: 3-oxobutanoyl-[ACP] + acetyl-[ACP] + H2O <=> (3S)-hydroxy-3-methylglutaryl-[ACP] + H(+) + holo-[ACP]


name: A + gibberellin A12 aldehyde + H2O <=> AH2 + gibberellin A12 + H(+)


name: GALK1 phosphorylates Gal to Gal1P (Rattus norvegicus)


name: 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O = (9Z)-octadecenoate + 1',3'-bis-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H(+)


name: ent-kaur-16-en-19-oate + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> gibberellin A12 + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: (9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + glycerol + H(+)


name: Phosphorylated MOB1A proteins associate with LATS proteins (Xenopus tropicalis)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Homo sapiens)


name: CO2 + formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + succinate => 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + O2


name: GOT2 dimer deaminates L-Asp (Mus musculus)


name: [protein]-C-terminal-L-glutamine + H2O => [protein]-C-terminal-L-glutamate + NH4(+)


name: ub-GLI is degraded by the proteasome (Sus scrofa)


name: D-arabinitol + NADP(+) => D-ribulose + H(+) + NADPH


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Gallus gallus)


name: PDP dephosphorylates p-lipo-PDH (Caenorhabditis elegans)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Sus scrofa)


name: CNRs bind CNR agonists (Canis familiaris)


name: Aquaporin-1 passively transports water into cell (Dictyostelium discoideum)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Danio rerio)


name: ENPEP hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) (Gallus gallus)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Canis familiaris)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Xenopus tropicalis)


name: (9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + glycerol + H(+)


name: CDK6 inhibitors bind CDK6 (Schizosaccharomyces pombe)


name: ATP + H2O + xanthine(out) = ADP + H(+) + phosphate + xanthine(in)


name: 2 a phenolic donor + H2O2 <=> 2 a phenolic radical donor + 2 H2O


name: BTK in active Gq-BTK complex is activated (Drosophila melanogaster)


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Saccharomyces cerevisiae)


name: (E)-caffeoyl-CoA + quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside => CoA + H(+) + quercetin 3-O-[(6-O-[(E)-caffeoyl]-beta-D-glucosyl)-(1->2)-beta-D-glucoside]


name: (5S)-hydroperoxy-(6E,8Z)-octadecadienoate + 2 glutathione = (5S)-hydroxy-(6E,8Z)-octadecadienoate + glutathione disulfide + H2O


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Xenopus tropicalis)


name: (3R)-3-hydroxy-2,3-dihydrotabersonine + A = (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + AH2


name: ISGylation of host proteins (Caenorhabditis elegans)


name: AMP(in) + CMP-N-acetyl-beta-neuraminate(out) => AMP(out) + CMP-N-acetyl-beta-neuraminate(in)


name: H2O + L-methionine + O2 = 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+)


name: (3S)-hydroxyhexadecanoyl-CoA = (2E)-hexadecenoyl-CoA + H2O


name: PAOX:FAD oxidises NASPN to SPM (Drosophila melanogaster)


name: HIF-alpha translocates from cytosol to nucleus (Rattus norvegicus)


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Rattus norvegicus)


name: cholesterol + PAPS => cholesterol sulfate + PAP (Canis familiaris)


name: NR3C2 binds fludrocortisone (Danio rerio)


name: fumarate + L-aspartate <=> iminosuccinate + succinate


name: (9Z)-octadecenoate + glycerol + H(+) => 1-(9Z-octadecenoyl)-glycerol + H2O


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = 3-hydroxy-3-methyl-2-oxobutanoate + H(+) + NADPH


name: SLC5A6 transports vitamins from extracellular region to cytosol (Xenopus tropicalis)


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Danio rerio)


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Rattus norvegicus)


name: 2-demethylmenaquinol-13 + S-adenosyl-L-methionine => H(+) + menaquinol-13 + S-adenosyl-L-homocysteine


name: CECRI deaminates Ade-Rib to Ino (Xenopus tropicalis)


name: HuR:mRNA complex translocates from the nucleus to the cytosol (Mus musculus)


name: (2E,6E)-farnesyl diphosphate + L-tryptophyl-[protein] = (2S,3R)-3-farnesyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate


name: KIT binds type II TKIs (Caenorhabditis elegans)


name: NADP(+) + phenanthrene-9,10-diol => 9,10-phenanthroquinone + H(+) + NADPH


name: FUT3 transfers L-fucose to Gal1,3GlcNAc (Homo sapiens)


name: IRAK4 is activated by autophosphorylation (Sus scrofa)


name: FMN + O2 <=> 8-demethyl-8-formylriboflavin 5'-phosphate + H2O


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Mus musculus)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Bos taurus)


name: AcK-NFE2L2 binds the AREG gene (Homo sapiens)


name: (S)-isoleucinol + H2O + NAD(+) = (3S)-1-hydroxy-3-methylpentan-2-one + H(+) + NADH + NH4(+)


name: PKA phosphorylates DARPP-32 on Thr34 (Canis familiaris)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) => 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol => 1,3-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-glycerol


name: p-Y701-STAT1 binds p-Y705-STAT3 (Xenopus tropicalis)


name: 5'-deoxyadenosine + E-Y cross-linked-[PQQ precursor protein] + H(+) + L-methionine => [PQQ precursor protein] + S-adenosyl-L-methionine


name: ATP + N(6)-(D-fructosyl)-L-lysine <=> ADP + H(+) + N(6)-(6-phospho-D-fructosyl)-L-lysine


name: PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Sus scrofa)


name: (R)-trihomocitrate + CoA + H(+) => 2-oxoheptanedioate + acetyl-CoA + H2O


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) <=> 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid <=> desmethyldescarbamoylnovobiocin + dTDP + H(+)


name: Binding of ADAR2 homodimer to dsRNA duplex (Xenopus tropicalis)


name: PCK1 phosphorylates OA to yield PEP (Sus scrofa)


name: ATP + beta-citrylglutamate(in) + H2O <=> ADP + beta-citrylglutamate(out) + H(+) + phosphate


name: Kinesin-3 is a dimer (Caenorhabditis elegans)


name: H(+) + iso-precytochalasin + NADPH + O2 <=> cytochalasin Z16 + H2O + NADP(+)


name: Beclin-1 complex translocates to the ER (Mus musculus)


name: 2'-O-methyluridine(2791) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(2791) in 21S rRNA


name: 26-oxohexacosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 26-hydroxyhexacosanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH


name: NEU3 cleaves GM3 to form LacCer (plasma membrane) (Bos taurus)


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Bos taurus)


name: structural constituent of nuclear lamina


name: 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] => 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+)


name: H(+) + NADH + perillyl aldehyde => NAD(+) + perillyl alcohol


name: MMP2, MMP7, MMP9 bind CD44 (Homo sapiens)


name: CK2 phosphorylates condensin I subunits (Canis familiaris)


name: arginine + H2O => ornithine + urea [ARG1] (Drosophila melanogaster)


name: LGI4 binds ADAM22,23,11 (Canis familiaris)


name: 2-oxoglutarate + L-arginine + O2 = (2S,3S)-hydroxyarginine + CO2 + succinate


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Schizosaccharomyces pombe)


name: IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Homo sapiens)


name: H(+) + octanoate + octanoylglycerol => dioctanoylglycerol + H2O


name: GIP receptor binds gastric inhibitory peptide (Mus musculus)


name: ERCC6 binds stalled RNA Pol II (Gallus gallus)


name: ORC6 binds KPNA1 or KPNA6 (Homo sapiens)


name: 3xPPCDC:3FMN decarboxylates PPC (Plasmodium falciparum)


name: Axonal transport of NGF:Trk complexes (Gallus gallus)


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Sus scrofa)


name: H(+) + ipsdienone + NADPH => (4R)-ipsdienol + NADP(+)


name: TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10 (Homo sapiens)


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Danio rerio)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Bos taurus)


name: JMJD1C demethylates H3K9 mono- and di-methylation (Rattus norvegicus)


name: dalnigrein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O => beta-D-apiofuranosyl-(1->6)-D-glucopyranose + dalnigrein + H(+)


name: (+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Degradation of newly synthesized ApoB-48 (Bos taurus)


name: (S)-1-aminoethylphosphonate + acetyl-CoA => [(1S)-1-acetamidoethyl]phosphonate + CoA


name: 2 AH2 + all-trans-beta-carotene + 2 O2 <=> 2 A + echinenone + 3 H2O


name: EP400 binds CDKN1A promoter (Rattus norvegicus)


name: PGM1:Mg2+ isomerises G1P to G6P (Drosophila melanogaster)


name: AH2 + diphosphate + nonaflavuxanthin => A + all-trans-lycopene + dimethylallyl diphosphate + H2O


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Sus scrofa)


name: 1-tuberculosinyladenosine + diphosphate => adenosine + H(+) + tuberculosinyl diphosphate


name: chloride(out) + hydrogencarbonate(in) => chloride(in) + hydrogencarbonate(out)


name: a carboxylate(in) + orotate(out) => a carboxylate(out) + orotate(in)


name: ADRM1 binds 26S proteasome (Dictyostelium discoideum)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Saccharomyces cerevisiae)


name: D-tyrosyl-tRNA(Tyr) + H2O => D-tyrosine + tRNA(Tyr)


name: CatSper Channel Mediated Calcium Transport (Homo sapiens)


name: CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-galactosamine => CMP-N-acetyl-beta-neuraminate + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine


name: c-FOS activation by phospho ERK1/2 (Mus musculus)


name: Deubiquitinated PTEN translocates to the cytosol (Bos taurus)


name: inulin fructotransferase (DFA-I-forming) activity


name: 4-terpineol + diphosphate => (2E)-geranyl diphosphate + H2O


name: (S)-eriodictyol + 2-oxoglutarate + O2 => (2R,3R)-dihydroquercetin + CO2 + succinate


name: Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (Homo sapiens)


name: H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + teasterone => 6alpha-hydroxytyphasterol + O2 + reduced [NADPH--hemoprotein reductase]


name: ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Bos taurus)


name: an aliphatic alcohol + decanoate + H(+) => decanoate ester + H2O


name: H(+) + jasmonate + NADPH + O2 => (1R,2R)-12-hydroxyjasmonate + H2O + NADP(+)


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Bos taurus)


name: 2-oxoglutarate(out) + hexanedioate(in) => 2-oxoglutarate(in) + hexanedioate(out)


name: p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Canis familiaris)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+) => 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-ethanolamine


name: a 3-oxoacyl-[ACP] + H(+) + NADH => a (3R)-hydroxyacyl-[ACP] + NAD(+)


name: cytidine(1400) in 16S rRNA + S-adenosyl-L-methionine => 5-methylcytidine(1400) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Homo sapiens)


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Sus scrofa)


name: an omega-hydroxy fatty acid + NAD(+) = an omega-oxo fatty acid + H(+) + NADH


name: Arachidonic acid is oxidised to 5S-HpETE by ALOX5 (Bos taurus)


name: CYP7B1 7-hydroxylates 25OH-CHOL (Bos taurus)


name: phenylethanolamine + S-adenosyl-L-methionine <=> H(+) + N-methylphenylethanolamine + S-adenosyl-L-homocysteine


name: Connexin 62 mediated neuronal gap junction communication (Bos taurus)


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Danio rerio)


name: a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycerol => a triacyl-sn-glycerol + glycerol


name: ARFRP1 recruits ARL1 to the TGN (Gallus gallus)


name: H(+) + methanol + oxaloacetate => H2O + oxaloacetate 4-methyl ester


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Homo sapiens)


name: β1,2-agonists bind ADRB1,2 (Homo sapiens)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Schizosaccharomyces pombe)


name: ferric iron transmembrane transporter activity


name: a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione <=> a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Rattus norvegicus)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + sn-glycerol 3-phosphocholine <=> (9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: a 2'-deoxyribonucleoside 5'-phosphate + H(+) + phosphate => a 2'-deoxyribonucleoside 5'-diphosphate + H2O


name: EGFR non-clathrin mediated endocytosis (Caenorhabditis elegans)


name: ATP + dimethylallyl diphosphate => diphosphate + N(6)-(dimethylallyl)adenosine 5'-triphosphate


name: NADH + 2 O2 => H(+) + NAD(+) + 2 superoxide


name: H2O + L-alanyl-tRNA(Pro) => H(+) + L-alanine + tRNA(Pro)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: [eIF5A protein]-N-(4-aminobutylidene)-L-lysine + H(+) + NADH <=> [eIF5A protein]-deoxyhypusine + NAD(+)


name: 3-hydroxy-3-methylglutarate + malonyl-CoA => (3S)-hydroxy-3-methylglutaryl-CoA + malonate


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Caenorhabditis elegans)


name: AH2 + H(+) + S-(hercyn-2-yl)-L-cysteine S-oxide => A + ergothioneine + NH4(+) + pyruvate


name: D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ (Xenopus tropicalis)


name: Formation of clathrin-coated vesicle (Homo sapiens)


name: H(+) + N-methylputrescine + S-adenosyl-L-homocysteine => putrescine + S-adenosyl-L-methionine


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + pentanoate => 1-hexadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + sn-glycerol 3-phosphate = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: H2O + monacolin L carboxylate => 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate


name: EPHAs bind EFNAs (Caenorhabditis elegans)


name: H2O + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: a 3'-end 3'-phospho-ribonucleotide-RNA + ATP => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + AMP + diphosphate


name: 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine => 2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine


name: L-citrulline + methylamine => H2O + N(omega)-methyl-L-arginine


name: p-S133 CREB1 dimer binds the CCND1 promoter (Homo sapiens)


name: CMP(out) + UDP-alpha-D-galactose(in) = CMP(in) + UDP-alpha-D-galactose(out)


name: genistein + UDP-alpha-D-glucose <=> genistein 7-O-beta-D-glucoside + H(+) + UDP


name: (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + sarcosine => (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + H(+) + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein]


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Caenorhabditis elegans)


name: Regulation of KIF20A (MKL2) by phosphorylation (Mus musculus)


name: alpha-D-ribose 1-phosphate = D-ribose 5-phosphate


name: 6-hydroxypseudooxynicotine + H2O2 => (R)-6-hydroxynicotine + H2O + O2


name: TP53 binds the PCBP4 gene (Homo sapiens)


name: ATP + N-acetyl-D-mannosamine <=> ADP + H(+) + N-acetyl-D-mannosamine 6-phosphate


name: H2O + L-alanyl-L-glutamine <=> L-alanine + L-glutamine


name: 3-sulfanylpentan-1-ol-L-cysteine + H2O <=> 3-sulfanyl-1-pentanol + NH4(+) + pyruvate


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Canis familiaris)


name: mTORC1 phosphorylates MAF1 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate => (2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate


name: (2R)-2-hydroperoxyhexadecanoate + H(+) <=> CO2 + H2O + pentadecanal


name: L-gulonate + NAD(+) = H(+) + keto-D-fructuronate + NADH


name: 2 CO2 + 2 formaldehyde + L-lysyl(27)-[histone H3] + 2 succinate => 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 O2


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Canis familiaris)


name: sucrose + H2O => glucose + fructose (Gallus gallus)


name: PTK6 phosphorylates CDKN1B (Homo sapiens)


name: PIAS2-2 SUMOylates THRA with SUMO3 (Gallus gallus)


name: 2-dehydro-3-deoxy-D-gluconate + ATP => 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+)


name: LONP1 binds mitochondrial inner membrane proteins (Gallus gallus)


name: (2R)-homocitrate => cis-homoaconitate + H2O


name: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + anthranilate + H(+)


name: Alkalization of the phagosomal lumen by NOX2 (Danio rerio)


name: Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B (Bos taurus)


name: p-Y705-STAT3, p-Y641-STAT6 dimerise (Mus musculus)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Caenorhabditis elegans)


name: 2-methylcyclopentanamine + H2O + NADP(+) <=> 2-methylcyclopentanone + H(+) + NADPH + NH4(+)


name: [amino-group carrier protein]-C-terminal-L-glutamate + L-ornithine => [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate + H2O


name: Formation of the 43S pre-initiation complex (Dictyostelium discoideum)


name: H2O + NAD(+) + phosphonoacetaldehyde => 2 H(+) + NADH + phosphonoacetate


name: (2E,6E)-farnesyl diphosphate => (+)-amorpha-4,11-diene + diphosphate


name: CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 (Homo sapiens)


name: 2-hydroxydodecanoate + H2O => dodecanoate + H2O2


name: voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization


name: HSP70 binds to HSP40:nascent protein (Mus musculus)


name: calmodulin-dependent protein phosphatase activity


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Homo sapiens)


name: RUNX3 binds the JAG1 gene promoter (Homo sapiens)


name: digallate + H2O = 2 3,4,5-trihydroxybenzoate + H(+)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Gallus gallus)


name: DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates


name: NFE2L2-dependent GSR gene expression (Homo sapiens)


name: CANDI binds CUL1 (Drosophila melanogaster)


name: H(+) + NADH + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose => NAD(+) + UDP-N-acetyl-alpha-D-quinovosamine


name: a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + S-adenosyl-L-methionine => a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Rattus norvegicus)


name: 3,7,11,15-tetramethylhexadecanoate + ATP + CoA <=> AMP + diphosphate + phytanoyl-CoA


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Schizosaccharomyces pombe)


name: Elastin degradation by MMP14 (Homo sapiens)


name: PTP-RO interacts with p-c-Kit complex (Rattus norvegicus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + Na(+)(out) => 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + Na(+)(in)


name: CoA + fumigaclavine A => acetyl-CoA + fumigaclavine B


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Plasmodium falciparum)


name: 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + H(+) + S-adenosyl-L-homocysteine => 2-sulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine


name: Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)


name: (3R)-3-[(carboxylmethyl)amino]decanoate + H(+) + holo-[ACP] <=> (2E)-decenoyl-[ACP] + glycine + H2O


name: ATP + NH4(+) + UTP => ADP + CTP + 2 H(+) + phosphate


name: OCT1 transports organic cations into hepatic cells (Caenorhabditis elegans)


name: Beta-defensins 1, 4A and 103 bind CCR6 (Canis familiaris)


name: ERO1B oxidizes P4HB (Plasmodium falciparum)


name: Acetylcholine synaptic vesicle docking and priming (Canis familiaris)


name: (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + H(+) + UDP => dammarenediol-II + UDP-alpha-D-glucose


name: (1R,2R,4R)-dihydrocarveol + NAD(+) => (1R,4R)-dihydrocarvone + H(+) + NADH


name: CYSLTR1 binds CYSLTR1 antagonists (Homo sapiens)


name: Activated AR binds RUNX2 (Xenopus tropicalis)


name: L-homocysteine + NH4(+) + pyruvate => H2O + L,L-cystathionine


name: BRIP1 (FANCJ) helicase functions in direct unwinding of DNA (Gallus gallus)


name: 1-(9S,13S-12-oxo-10,15Z-phytodienoyl)-2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = (9S,13S,15Z)-12-oxophyto-10-15-dienoate + 2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+)


name: 2beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + testosterone


name: (S)-coclaurine + H(+) + S-adenosyl-L-homocysteine => (S)-norcoclaurine + S-adenosyl-L-methionine


name: Activated FGFR4 phosphorylates FRS2 (Caenorhabditis elegans)


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Rattus norvegicus)


name: Degradation of ubiquitinated SMAD3 (Gallus gallus)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Mus musculus)


name: RPA binds to the Flap (Plasmodium falciparum)


name: CO2 + cycloeucalenone + NADH => 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + NAD(+)


name: Acyl Ghrelin and C-Ghrelin are secreted (Canis familiaris)


name: 6-deoxy-6-sulfo-D-fructose + D-erythrose 4-phosphate = (2S)-3-sulfolactaldehyde + D-sedoheptulose 7-phosphate


name: HP1 alpha binds Histone H3K9(me)3 (Danio rerio)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Gallus gallus)


name: Association of procollagen type IV (Homo sapiens)


name: H2O + indole-3-acetaldehyde + O2 = (indol-3-yl)acetate + H(+) + H2O2


name: 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O <=> 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxylate + H(+) + holo-[ACP]


name: Free APC/C phosphorylated by Plk1 (Bos taurus)


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Mus musculus)


name: 7-oxopregnenolone + H(+) + NADPH = 7beta-hydroxypregnenolone + NADP(+)


name: "With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"


name: chlorophyll b + H(+) + NADPH => 7(1)-hydroxychlorophyll a + NADP(+)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + UDP