name: 1-acyl LPI is acylated to PI by MBOAT7 (Xenopus tropicalis)


name: CTP + UTP <=> cyclic CMP-UMP + 2 diphosphate


name: ASPA deacetylates NAA to acetate and L-aspartate (Sus scrofa)


name: ATP + L-fucose => ADP + beta-L-fucose 1-phosphate + H(+)


name: LMAN family proteins bind glycosylated cargo (Dictyostelium discoideum)


name: 3-bromo-2-heptyl-1-methoxy-4(1H)-quinolinone + H(+) + S-adenosyl-L-homocysteine => 3-bromo-2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine


name: a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + H(+) + UDP


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Rattus norvegicus)


name: CoA + H(+) + O-(2-acetamidoethyl)-L-serine => acetyl-CoA + O-(2-aminoethyl)-L-serine


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)


name: a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein] => a very-long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Caenorhabditis elegans)


name: FPGS-2 transforms THF to THFPG (Xenopus tropicalis)


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Rattus norvegicus)


name: LDLR is bound by DAB2 and ARH (Homo sapiens)


name: dimethylallyl diphosphate + preechinulin = diphosphate + tardioxopiperazine A


name: p-T,Y MAPK dimers translocate to nucleus (Canis familiaris)


name: Dentin phosphoprotein binds integrin alphaVbeta1 (Homo sapiens)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine


name: Formation of Cyclin A:Cdk2 complexes (Sus scrofa)


name: 1-O-hexadecyl-2-propanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate => (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O


name: KEN dimer represses transcription (Drosophila melanogaster)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Gallus gallus)


name: E2F1 binds APAF1 gene promoter (Homo sapiens)


name: Incorrectly folded glycoproteins translocate to the ERQC (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Homo sapiens)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Danio rerio)


name: an N-acyl-D-glucosamine = an N-acyl-D-mannosamine


name: a medium-chain fatty acyl-CoA + H2O => a medium chain fatty acid + CoA + H(+)


name: RHAG transports CO2 from extracellular region to cytosol (Sus scrofa)


name: (2E)-eicosenoyl-CoA + H(+) + NADPH => eicosanoyl-CoA + NADP(+)


name: glycochenodeoxycholate(out) + 2 Na(+)(out) => glycochenodeoxycholate(in) + 2 Na(+)(in)


name: p-STAT3 dimerizes (Caenorhabditis elegans)


name: 4-phospho-D-erythronate + NAD(+) <=> 3-dehydro-4-O-phospho-D-erythronate + H(+) + NADH


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Danio rerio)


name: an 8-hydroxyflavone + S-adenosyl-L-methionine => an 8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: Exocytosis of ficolin-rich granule membrane proteins (Drosophila melanogaster)


name: H(+)(in) + L-histidine(in) + L-ornithine(out) = H(+)(out) + L-histidine(out) + L-ornithine(in)


name: cholesteryl 3-beta-D-glucoside + N-hexadecanoylsphing-4-enine => beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + cholesterol


name: PP2A-B56 dephosphorylates centromeric cohesin (Rattus norvegicus)


name: [(3R)-hydroxybutanoate](n) + H2O = (3R)-hydroxybutanoate tetramer + [(3R)-hydroxybutanoate](n-4) + H(+)


name: H2O + L-prolinamide => L-proline + NH4(+)


name: CDKN1A (p21) gene expression is positively regulated by RUNX3 and ZFHX3 (Homo sapiens)


name: AKAP8L binds MLL2 complex (Mus musculus)


name: TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA (Homo sapiens)


name: SPRY2 translocates to the plasma membrane (Rattus norvegicus)


name: Laminins:Nidogens binds HSPG2 (Homo sapiens)


name: COP9 and TOR1 deneddylate STON2 (Rattus norvegicus)


name: PAK1-3 autophosphorylates (Caenorhabditis elegans)


name: Aquaporin-9 passively transports glycerol into cell (Xenopus tropicalis)


name: Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 (Homo sapiens)


name: an N-acylsphinganine + NAD(+) => H(+) + N-acyl-3-oxosphinganine + NADH


name: (9Z)-hexadecen-1-ol + (9Z)-octadecenoyl-CoA => 1-O-(9Z)-hexadecenyl (9Z)-octadecenoate + CoA


name: (2S)-2-acetolactate + H(+) + NADPH => (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+)


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Canis familiaris)


name: TXLNA (IL14) binds syntaxin3 (Gallus gallus)


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Xenopus tropicalis)


name: CTP(out) + UDP(in) => CTP(in) + UDP(out)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Xenopus tropicalis)


name: USP10 deubiquitinates SNX3, CFTR (Saccharomyces cerevisiae)


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Canis familiaris)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Danio rerio)


name: 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP(+) => 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + H(+) + NADPH


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Sus scrofa)


name: YWHAZ binds p-CBY:CTNNB1 (Canis familiaris)


name: CYP3A4 binds CYP3A4 inhibitors (Homo sapiens)


name: HSF1 trimer translocates to the nucleus (Mus musculus)


name: 3-sulfopyruvate + H(+) + NADPH => (2R)-3-sulfolactate + NADP(+)


name: hydrolase activity, acting on acid phosphorus-nitrogen bonds


name: N-hydroxy-L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Dephosphorylation of STAT1 by SHP2 (Rattus norvegicus)


name: NaS2 co-transports sulphate and two sodium ions (Canis familiaris)


name: an (S)-2-haloacid + H2O <=> a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Mus musculus)


name: Myristoylation of tBID by NMT1 (Mus musculus)


name: TDP1 and TDP2 process unligatable DSB ends (Homo sapiens)


name: 2-oxoglutarate + L-aspartyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: ULK1 is dephosphorylated (Rattus norvegicus)


name: 2-oxoglutarate + O2 + thymine = 5-hydroxymethyluracil + CO2 + succinate


name: cyathadiol + O2 + reduced [NADPH--hemoprotein reductase] <=> cyathatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Xenopus tropicalis)


name: PTK6 phosphorylates KHDRBS2 (Danio rerio)


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Saccharomyces cerevisiae)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Xenopus tropicalis)


name: (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NADP(+) <=> 4-methylcatechol + CO2 + NADPH


name: (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B <=> aspoquinolone B


name: RGGT geranylgeranylates RAB proteins (Rattus norvegicus)


name: glycyl-L-glutamine(out) + H(+)(out) = glycyl-L-glutamine(in) + H(+)(in)


name: trypanothione-disulfide reductase (NADP) activity


name: 2 Fe(III)-[cytochrome c3] + H2 = 2 Fe(II)-[cytochrome c3] + 2 H(+)


name: Basigin binds Matrix metalloproteinase-1 (Homo sapiens)


name: alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+) => beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose


name: dihydroorotate dehydrogenase (NADH) activity


name: aldarate transmembrane transporter activity


name: Formation of a heteromeric BMP receptor complex (Bos taurus)


name: GRB2:GAB1 binds to phosphorylated EGFR (Homo sapiens)


name: H2O + N-(9Z-octadecenoyl)-taurine => (9Z)-octadecenoate + taurine


name: Y693-STAT4 dimer translocates to the nucleus (Dictyostelium discoideum)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Saccharomyces cerevisiae)


name: all-trans-retinal + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-retinol + O2 + reduced [NADPH--hemoprotein reductase]


name: (S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate => 2-(3,5-dihydroxyphenyl)-2-oxoacetate + L-glutamate


name: PRDX1 overoxidizes (Caenorhabditis elegans)


name: H2O + N,1-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(9Z-octadecenoyl) ethanolamine


name: Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker (Homo sapiens)


name: ACSM2B-like proteins transform ST to ST-CoA (Mus musculus)


name: (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-dihydrotricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-hexacosanoylsphinganine => a 1,2-diacyl-sn-glycerol + N-(hexacosanoyl)-sphinganine-1-(1D-myo-inositol)


name: bicarbonate transmembrane transporter activity


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Danio rerio)


name: AH2 + ATP + 2 Co(II)-[trimethylamine-specific corrinoid protein] + H2O = A + ADP + 2 Co(I)-[trimethylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Canis familiaris)


name: a globoside IV3GalNAc-Gb4Cer + H2O => a globoside Gb4Cer + N-acetyl-alpha-D-galactosamine


name: voltage-gated monoatomic ion channel activity


name: dodecanoyl-[ACP] + H2O => dodecanoate + H(+) + holo-[ACP]


name: Caspase-7 translocates to the nucleus (Canis familiaris)


name: RHOU binds effectors at the plasma membrane (Dictyostelium discoideum)


name: 5'-deoxyadenosine + archaeosine(15) in tRNA + 2 H(+) + L-1-piperideine-6-carboxylate + L-methionine => 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA + S-adenosyl-L-methionine


name: acetyl-CoA + H2O + oxaloacetate <=> citrate + CoA + H(+)


name: RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the MIR27A gene promoter (Homo sapiens)


name: (20S)-protopanaxatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (20S)-protopanaxadiol + O2 + reduced [NADPH--hemoprotein reductase]


name: PDPK1 phosphorylates PKN1,2,3 (Saccharomyces cerevisiae)


name: D-glutamate + H2O + O2 <=> 2-oxoglutarate + H2O2 + NH4(+)


name: 2-oxoglutarate + hexyl sulfate + O2 = CO2 + H(+) + hexanal + succinate + sulfate


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Canis familiaris)


name: 5-methoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine => 5-hydroxyuridine(34) in tRNA + S-adenosyl-L-methionine


name: S-adenosyl-L-methionine + zymosterol <=> fecosterol + H(+) + S-adenosyl-L-homocysteine


name: H2O + heptanal + NAD(+) = 2 H(+) + heptanoate + NADH


name: RHOH binds effectors at the plasma membrane (Caenorhabditis elegans)


name: H2O + N-phenylhydroxylamine + 2 NADP(+) = 2 H(+) + 2 NADPH + nitrobenzene


name: glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol (Mycobacterium tuberculosis)


name: Abortive termination of elongation after arrest (Bos taurus)


name: Calcineurin binds NFATC1,2,3 (Bos taurus)


name: (2S,3R)-dihydrodehydrodiconiferyl alcohol + H(+) + NADPH <=> (R)-tetrahydrodehydrodiconiferyl alcohol + NADP(+)


name: NR3C2 binds NR3C2 antagonists (Gallus gallus)


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Homo sapiens)


name: 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z)-docosapentaenoate => (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2


name: D-maltotriose + H2O <=> alpha-D-glucose + D-maltose


name: H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O


name: all-trans-4-hydroxyretinol + H2O + 2 oxidized [adrenodoxin] => all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: ATM phosphorylates ZNF420 (Rattus norvegicus)


name: ADP + D-fructose(in) + H(+) + phosphate => ATP + D-fructose(out) + H2O


name: 3 H(+) + holo-[2-methylbutanoate polyketide synthase] + 2 malonyl-CoA + 2 NADPH + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CO2 + 2 CoA + H2O + 2 NADP(+) + S-adenosyl-L-homocysteine


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Canis familiaris)


name: NADP(+) + prostaglandin D2 <=> 15-oxoprostaglandin D2 + H(+) + NADPH


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Drosophila melanogaster)


name: AGT(34-41) binds to AGTR1 (Caenorhabditis elegans)


name: CSNK1A1 and ADRBK1 dissociate from p-SMO dimer (Homo sapiens)


name: ATP12A:ATP4B exchanges K+ for H+ (Sus scrofa)


name: Butyrylcholinesterase hydrolyzes acyl Ghrelin (Canis familiaris)


name: 3-sulfino-L-alanine: proton, glutamate antiporter activity


name: 3-sulfino-L-alanine(out) + H(+)(in) + L-glutamate(in) = 3-sulfino-L-alanine(in) + H(+)(out) + L-glutamate(out)


name: MMACHC:cob(II)alamin binds MMADHC (Bos taurus)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Homo sapiens)


name: HGFAC cleaves pro-HGF to form HGF dimer (Bos taurus)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-glucose = alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: D-loop extension by DNA polymerases (Bos taurus)


name: Inactivation of LCK by PTPN22 (Rattus norvegicus)


name: ESR1 binds ESR1 antagonists (Sus scrofa)


name: Active FLT3 binds to SLA2 (Canis familiaris)


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Homo sapiens)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Rattus norvegicus)


name: BIL binds GSTA1, FABP1 (Rattus norvegicus)


name: Connexin 62 mediated neuronal gap junction communication (Sus scrofa)


name: Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Xenopus tropicalis)


name: Recruitment of PLC-gamma1 to SLP-76 (Homo sapiens)


name: 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA + A + 2 ADP + 2 H(+) + 2 phosphate => 3-hydroxybenzoyl-CoA + AH2 + 2 ATP + 2 H2O


name: ATP + carbamoyl phosphate + H2O <=> carbamoyl adenylate + diphosphate + phosphate


name: docosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 2-hydroxydocosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: 2-oxoglutarate + O2 + prekainate => CO2 + H2O + kainate + succinate


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ATP + H2O <=> a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ADP + H(+) + phosphate


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Gallus gallus)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Drosophila melanogaster)


name: RUNX3 binds the NOTCH1 coactivator complex (Gallus gallus)


name: 5-hydroxyisourate + H2O <=> 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = diphosphate + hydropyrenol


name: 4-methylpentanoate + ATP + CoA <=> 4-methylpentanoyl-CoA + AMP + diphosphate


name: a fatty acylamide + H2O => a fatty acid + NH4(+)


name: PRICKLE1 is degraded by the proteasome (Caenorhabditis elegans)


name: agmatine(in) + H(+)(out) = agmatine(out) + H(+)(in)


name: 2 H(+)(out) + H2O + menaquinone-8 + nitrite => 2 H(+)(in) + menaquinol-8 + nitrate


name: NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Homo sapiens)


name: 1D-myo-inositol 1,3,4-trisphosphate + H2O => 1D-myo-inositol 3,4-bisphosphate + phosphate


name: Dissociation of the Prostacyclin receptor:Gs complex (Homo sapiens)


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Mus musculus)


name: ITPA hydrolyses XTP to XMP (Dictyostelium discoideum)


name: L-ascorbate(in) + monodehydro-L-ascorbate radical(out) => L-ascorbate(out) + monodehydro-L-ascorbate radical(in)


name: a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O


name: estrone 3-sulfate(out) + succinate(in) = estrone 3-sulfate(in) + succinate(out)


name: 2-oxoglutarate + L-lysine + O2 => (4R)-4-hydroxy-L-lysine + CO2 + succinate


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Drosophila melanogaster)


name: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Bos taurus)


name: H2O + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(9Z-octadecenoyl) ethanolamine


name: all-trans-antheraxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Trimerization of TRAIL:TRAIL receptor complex (Homo sapiens)


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Homo sapiens)


name: ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Mus musculus)


name: PMM1,2 isomerise Man6P to Man1P (Mus musculus)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O => 2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Canis familiaris)


name: Association of procollagen type VI (Bos taurus)


name: S-adenosyl 3-(methylsulfanyl)propylamine + spermine = H(+) + N(4)-aminopropylspermine + S-methyl-5'-thioadenosine


name: Caspase-6 translocates to the nucleus (Sus scrofa)


name: (3R)-3-hydroxy-L-aspartate => glycine + glyoxylate


name: ATP + GDP => AMP + guanosine 3',5'-bis(diphosphate)


name: a 2-acylglycerol + an acyl-CoA => a 2,3-diacyl-sn-glycerol + CoA


name: AMP + D-phenylalanine + diphosphate + H(+) => ATP + H2O + L-phenylalanine


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Canis familiaris)


name: BCHE hydrolyzes ASA- (Rattus norvegicus)


name: FGFRL1 dimer binds FGFs (Xenopus tropicalis)


name: FGFRL1 dimer binds FGFs (Rattus norvegicus)


name: H2O + L-valine + NADP(+) <=> 3-methyl-2-oxobutanoate + H(+) + NADPH + NH4(+)


name: (20S)-ginsenoside F1 + D-glucose => (20S)-ginsenoside Rg1 + H2O


name: H2O + L-seryl-tRNA(Ala) = L-serine + tRNA(Ala)


name: D-xylulose + H(+) + NADH => D-arabinitol + NAD(+)


name: Formation of ORC(1-5) complex (Rattus norvegicus)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Bos taurus)


name: Rheb in the MTORC1 complex hydrolyses GTP (Danio rerio)


name: tricaffeoyl spermidine O-methyltransferase activity


name: Oxytocin receptor bind oxytocin (Gallus gallus)


name: 3 H2O2 + protoporphyrin IX => 3 O2 + protoporphyrinogen IX


name: PAAP-A proteolyzes IGF:IGFBP4 (Bos taurus)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Schizosaccharomyces pombe)


name: NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Mus musculus)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Bos taurus)


name: dimethylallyl diphosphate + H2O = dimethylallyl phosphate + H(+) + phosphate


name: cytidine(2870) in 25S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(2870) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 2-hydroxy-3-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine


name: 4-(trifluoromethyl)benzyl alcohol + NAD(+) <=> 4-(trifluoromethyl)benzaldehyde + H(+) + NADH


name: dihydro-6-demethylsterigmatocystin + S-adenosyl-L-methionine = dihydrosterigmatocystin + H(+) + S-adenosyl-L-homocysteine


name: isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Caenorhabditis elegans)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Canis familiaris)


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Drosophila melanogaster)


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Dictyostelium discoideum)


name: (3R)-citramalyl-CoA => acetyl-CoA + pyruvate


name: (R)-dihydrolipoate + ATP + L-lysyl-[lipoyl-carrier protein] => AMP + diphosphate + H(+) + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein]


name: 4,4'-diaponeurosporenal + H2O + NAD(+) => 4,4'-diaponeurosporenoate + 2 H(+) + NADH


name: DAG is metabolized by DAGL to 2-AG (Rattus norvegicus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Homo sapiens)


name: didemethylasterriquinone D + dimethylallyl diphosphate <=> asterriquinone C1 + diphosphate


name: PLC gamma 2-mediated PIP2 hydrolysis (Xenopus tropicalis)


name: 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2 = CO2 + H2O + NAD(+) + naphthalene-1,2-diol


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: Necl-1:Necl-2 trans heterodimer interaction (Homo sapiens)


name: L-threonate + NAD(+) = 2-dehydro-L-erythronate + H(+) + NADH


name: Tyrosine is hydroxylated to dopa (Drosophila melanogaster)


name: SHPK phosphorylates Sedo to Sedo7P (Bos taurus)


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Homo sapiens)


name: CDK4 inhibitors bind CDK4 (Canis familiaris)


name: NLK phosphorylates TCF/LEF (Canis familiaris)


name: dimethyl sulfide + H2O + menaquinone-8 => dimethyl sulfoxide + menaquinol-8


name: 2-oxoglutarate(out) + maleate(in) <=> 2-oxoglutarate(in) + maleate(out)


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Caenorhabditis elegans)


name: AKT2 binds PIP3 (Dictyostelium discoideum)


name: 5-S-cysteinyldopaquinone + L-dopa => 5-S-cysteinyldopa + L-dopaquinone


name: Active ALK dimer binds IRS1 (Canis familiaris)


name: ERBB4 forms heterodimers with ERBB3 (Sus scrofa)


name: RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the ITGA2B promoter (Homo sapiens)


name: ABCC1 transports cytosolic RCbl to extracellular region (Rattus norvegicus)


name: 2 Na(+)(out) + phosphate(out) <=> 2 Na(+)(in) + phosphate(in)


name: I-Smad competes with Co-Smad for R-Smad1/5/8 (Bos taurus)


name: A + H2O + N(6)-methyl-L-lysyl(4)-[histone H3] = AH2 + formaldehyde + L-lysyl(4)-[histone H3]


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Gallus gallus)


name: apelin-17 + H2O <=> apelin-16 + L-phenylalanine


name: Dimethyl fumarate modifies Cys191 in GSDMD (Gallus gallus)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: borate efflux transmembrane transporter activity


name: an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate => an alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Danio rerio)


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + menadiol = diphosphate + menaquinol-4


name: H2O + thiamine diphosphate <=> H(+) + phosphate + thiamine phosphate


name: Active G alpha (q) binds RGS proteins (Xenopus tropicalis)


name: 3-(indol-3-yl)lactate + NAD(+) = H(+) + indole-3-pyruvate + NADH


name: 2'-O-methylguanosine(1145) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine => guanosine(1145) in 16S rRNA + S-adenosyl-L-methionine


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Autoglucosylation of GYG1 complexed with GYS1-a (Bos taurus)


name: CDK5R1 gene expression is stimulated by NPAS4 (Homo sapiens)


name: 2-phenylethanol + NAD(+) => 2-phenylacetaldehyde + H(+) + NADH


name: ESD dimer hydrolyses S-FGSH to GSH (Canis familiaris)


name: GAA hydrolyzes lysosomal glycogen (Mus musculus)


name: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Xenopus tropicalis)


name: B-WICH recruits histone acetyltransferases (Canis familiaris)


name: A + all-trans-4,4'-diapolycopen-4-al + H2O => AH2 + all-trans-4,4'-diapolycopen-4-oate + H(+)


name: a long-chain fatty acyl ethyl ester + H2O <=> a long-chain fatty acid + ethanol + H(+)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Canis familiaris)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Canis familiaris)


name: adenosine(1785)/adenosine(1786) in 18S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1785)/N(6)-dimethyladenosine(1786) in 18S rRNA + 4 S-adenosyl-L-homocysteine


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Homo sapiens)


name: FFAR1:FFAR1 ligands activates Gq (Rattus norvegicus)


name: 3-oxoisoapionate + H(+) => CO2 + L-erythrulose


name: a 1,2-diacylglycerol + a 1-acylglycerol => a triacylglycerol + glycerol


name: Recruitment and activation of Chk1 (Rattus norvegicus)


name: Exocytosis of specific granule membrane proteins (Xenopus tropicalis)


name: a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: 2,4-dinitrophenyl-S-glutathione + chloride + H(+) => 1-chloro-2,4-dinitrobenzene + glutathione


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Rattus norvegicus)


name: 1-O-alkyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine + H(+) => 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + sphing-4-enine


name: p-SHC1 binds integrin alpha5beta1:fibronectin (Homo sapiens)


name: AMP + ATP + H(+) => 5'-triphosphoadenylyl-(2'->5')-adenosine + H2O


name: UMPS dimer decarboxylates OMP to UMP (Canis familiaris)


name: PTPRF, PTPRS, PTPRD bind Liprins (Canis familiaris)


name: PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA (Sus scrofa)


name: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin


name: UCKL1 phosphorylates urindine, cytidine (Caenorhabditis elegans)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Xenopus tropicalis)


name: MASTL phosphorylates ENSA (Drosophila melanogaster)


name: (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Bos taurus)


name: PI3K synthesizes PIP3 downstream of ALK (Mus musculus)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Xenopus tropicalis)


name: Formation of dehydro-lysinonorleucine cross-links (Xenopus tropicalis)


name: barbiturate + H2O <=> 3-oxo-3-ureidopropanoate


name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Canis familiaris)


name: a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in mRNA + S-adenosyl-L-methionine


name: ATP + xylitol = ADP + H(+) + xylitol 5-phosphate


name: CoA + NAD(+) + pentanal => H(+) + NADH + pentanoyl-CoA


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: D-fructuronate(in) + H(+)(in) = D-fructuronate(out) + H(+)(out)


name: 5-formimidoyltetrahydrofolate + glycine => (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine


name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex (Bos taurus)


name: PG and CDP-DAG are converted to CL by CRLS1 (Mus musculus)


name: (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O => resolvin E1


name: CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Drosophila melanogaster)


name: glycolate(out) + H(+)(out) => glycolate(in) + H(+)(in)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Homo sapiens)


name: H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] => (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Translocation of Ezrin to plasma membrane (Drosophila melanogaster)


name: cholesteryl (9Z,12Z)-octadecadienoate(in) => cholesteryl (9Z,12Z)-octadecadienoate(out)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Rattus norvegicus)


name: a 5-methylcytidine in RNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in RNA + S-adenosyl-L-methionine


name: G13 activation by TP receptor (Xenopus tropicalis)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphate = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate


name: GUCYs converts GTP to cGMP (Dictyostelium discoideum)


name: H(+) + NADPH + zymosterone <=> NADP(+) + zymosterol


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-2-O-methyl-sn-glycerol <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-2-O-methyl-3-(9Z)-octadecenoyl-sn-glycerol


name: ZIP6 and ZIP14 mediate zinc influx into cells (Mus musculus)


name: cadaverine(out) + L-lysine(in) => cadaverine(in) + L-lysine(out)


name: NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Mus musculus)


name: Conversion of C4 into C4a and C4b (Xenopus tropicalis)


name: Intrinsic nucleotide exchange on RAS (Homo sapiens)


name: glycerol 2-phosphate + H2O = glycerol + phosphate


name: H2O + melatonin = 5-methoxytryptamine + acetate


name: RAC2 translocates to the phagocytic vesicle membrane (Mus musculus)


name: 2-phenylacetate + ATP + CoA => AMP + diphosphate + phenylacetyl-CoA


name: a 1,3-diacyl-sn-glycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)


name: diphosphate + S-(2E,6E)-farnesyl-L-cysteinyl-[protein] => (2E,6E)-farnesyl diphosphate + L-cysteinyl-[protein]


name: Phosphorylation of pPTK2 by SRC (Bos taurus)


name: 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+) => D-dopa + H2O + O2


name: (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+) => H2O + L-isoleucine + O2


name: snRNA Cap hypermethylation (Rattus norvegicus)


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Bos taurus)


name: Fe(III)-{di[N-(2,3-dihydroxybenzoyl)-L-seryl]-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + H(+) + H2O = Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + N-(2,3-dihydroxybenzoyl)-L-serine


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Drosophila melanogaster)


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Homo sapiens)


name: The Interleukin 1 receptor complex binds Tollip (Mus musculus)


name: AS3MT transfers CH3 from AdoMet to arsenite(3-) (Rattus norvegicus)


name: ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Dictyostelium discoideum)


name: ATP + citrate + N(5)-[(S)-citryl]-D-ornithine <=> AMP + diphosphate + H(+) + staphyloferrin A


name: all-trans-13,14-dihydroretinol + NAD(+) <=> all-trans-13,14-dihydroretinal + H(+) + NADH


name: Cleavage of Procaspase‑9 to caspase‑9 (Mus musculus)


name: a 5,6-dihydrouridine in RNA + NAD(+) => a uridine in RNA + H(+) + NADH


name: branched-chain amino acid transmembrane transporter activity


name: SLC25A44 transports Leu, Ile and Val from cytosol to mitochondrial matrix (Homo sapiens)


name: ATF2 acetylates histone H2B, H4 (Gallus gallus)


name: acetylcholine(out) + 2 H(+)(in) = acetylcholine(in) + 2 H(+)(out)


name: [HPr protein]-O-phospho-L-serine + H(+) + phosphate <=> [HPr protein]-L-serine + diphosphate


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Sus scrofa)


name: (3R)-hydroxytetradecanoyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = holo-[ACP] + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine


name: (2E)-geranyl diphosphate => (2R,4S)-bornyl diphosphate


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Dictyostelium discoideum)


name: Activation of Rap1 by membrane-associated GEFs (Saccharomyces cerevisiae)


name: a 14alpha-formyl steroid + O2 + reduced [NADPH--hemoprotein reductase] = a Delta(14) steroid + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Xenopus tropicalis)


name: Interaction of integrin alpha8beta1 with Tenascin-C (Caenorhabditis elegans)


name: 6-carboxyhexanoyl-CoA + H(+) + L-alanine => (8S)-8-amino-7-oxononanoate + CO2 + CoA


name: FLVCR1-1 transports heme from cytosol to extracellular region (Bos taurus)


name: a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + L-lysyl-[protein] => a 5'-end diphospho-adenosine in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein]


name: H2O + quercetin 4'-O-beta-D-glucoside <=> beta-D-glucose + quercetin


name: 2 H2O + 2 leukotriene A4 + O2 => 2 lipoxin B4


name: "With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)"


name: 2 Na(+)(in) + urate(in) => 2 Na(+)(out) + urate(out)


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Sus scrofa)


name: 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] <=> 17beta,18-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Nephrin trans-homophilic interaction (Drosophila melanogaster)


name: Transport of fringe-modified NOTCH to plasma membrane (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol = a 1-acyl-sn-glycero-3-phosphocholine + a 2,3-diacyl-sn-glycerol


name: a 2-oxocarboxylate + L-methionine <=> 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid


name: 3-deoxyglucosone + H2O + NAD(+) <=> 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Xenopus tropicalis)


name: H2O + NADP(+) + succinate semialdehyde <=> 2 H(+) + NADPH + succinate


name: Na(+)(out) + xanthine(out) => Na(+)(in) + xanthine(in)


name: MVB Vesicle Formation (Canis familiaris)


name: p-PKR dimer phosphorylates MAPT (Rattus norvegicus)


name: B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD (Bos taurus)


name: 3 H(+) + hydrogen sulfide + L-aspartate 4-semialdehyde + reduced 2[4Fe-4S]-[ferredoxin] => H2O + L-homocysteine + oxidized 2[4Fe-4S]-[ferredoxin]


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Dictyostelium discoideum)


name: SDS dimers:PXLP dehydrate L-Thr to 2AA (Homo sapiens)


name: HDAC8 deacetylates histones (Plasmodium falciparum)


name: (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 => (7S,14S)-dihydroperoxy-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoate


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Bos taurus)


name: Formation of Elongin complex (Rattus norvegicus)


name: MDM2 translocates to the cytosol (Xenopus tropicalis)


name: 3'-phosphoadenylyl sulfate + 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) => 3alpha-hydroxyetiocholan-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: IL12B:IL12B translocates from ER lumen to the extracellular region (Gallus gallus)


name: 3-hydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine => 3-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine


name: adenosine 5'-phosphoramidate + H2O <=> AMP + NH4(+)


name: UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Gallus gallus)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Sus scrofa)


name: extracellular ammonia-gated monoatomic ion channel activity


name: long-chain fatty acid--protein ligase activity


name: (S)-malate + ubiquinone-8 => oxaloacetate + ubiquinol-8


name: 9-cis-4-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase] => 9-cis-4-oxoretinoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PLEKHA3,8 bind PI4P, ARF1 (Xenopus tropicalis)


name: HCMV Genome Replication Completion (Homo sapiens)


name: The Ligand:GPCR:Gi complex dissociates (Gallus gallus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: H2O + NAD(+) + sulfoacetaldehyde <=> 2 H(+) + NADH + sulfoacetate


name: (R)-lanthionine ketimine + 2 H(+) + NADPH <=> (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+)


name: H(+) + N(6),N(6)-dimethyl-L-lysine => CO2 + N,N-dimethyl-cadaverine


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Canis familiaris)


name: (-)-cyatha-3,12-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> erinacol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dissociation of p-T,Y-MAPK3:MAP2K1 (Caenorhabditis elegans)


name: The Ligand:GPCR:Gi complex dissociates (Sus scrofa)


name: 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase]


name: guanosine(18) in tRNA + S-adenosyl-L-methionine => 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: P2X1-mediated entry of Ca++ from plasma (Rattus norvegicus)


name: Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester


name: deoxyviolaceinate + H(+) + O2 <=> CO2 + deoxyviolacein + H2O


name: GLI3R translocates to the nucleus (Drosophila melanogaster)


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Sus scrofa)


name: 2-dehydro-3-deoxy-D-gluconate + ATP <=> 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Homo sapiens)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus (Bos taurus)


name: 3'-phosphoadenylyl sulfate + 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(beta-D-glucuronate) => 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: (2Z,6Z)-farnesyl diphosphate => diphosphate + germacrene C


name: Activated FGFR4 phosphorylates PPTN11 (Drosophila melanogaster)


name: docosanoate + glycine => H2O + N-docosanoylglycine


name: (R)-pantetheine + phosphate => (R)-4'-phosphopantetheine + H2O


name: H(+) + N(6),N(6)-dimethyl-L-lysine = CO2 + N,N-dimethyl-cadaverine


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Bos taurus)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Homo sapiens)


name: RIPK1 is cleaved by CASP8:FLIP(L) (Homo sapiens)


name: (Z)-2-phenyl-1-thioacetohydroximate + UDP-alpha-D-glucose = (Z)-desulfoglucotropeolin + UDP


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2 = 18S-resolvin E2 + A + H2O


name: 5-hydroxyisourate + H2O + NADP(+) => H(+) + NADPH + O2 + urate


name: ent-7alpha-hydroxykaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] => gibberellin A12 aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: acetyl-CoA + ATP + hydrogencarbonate <=> ADP + H(+) + malonyl-CoA + phosphate


name: (1R,2S,4R)-neodihydrocarveol + NAD(+) = (1R,4R)-dihydrocarvone + H(+) + NADH


name: (E,E)-piperate + ATP + CoA => (E,E)-piperoyl-CoA + AMP + diphosphate


name: IC-asc-C7-CoA + O2 <=> H2O2 + IC-asc-DeltaC7-CoA


name: 1-hexadecanoylglycerone 3-phosphate + hexadecan-1-ol <=> 1-O-hexadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Bos taurus)


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Mus musculus)


name: ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus (Xenopus tropicalis)


name: Activated PCLG1 dissociates from NTRK3 (Sus scrofa)


name: 2-aminopentanenitrile + H(+) + 2 H2O <=> L-2-aminopentanoate + NH4(+)


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Bos taurus)


name: RBKS phosphorylates ribose to R5P (Drosophila melanogaster)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Caenorhabditis elegans)


name: petunidin + UDP-alpha-D-galactose <=> petunidin 3-O-beta-D-galactoside + UDP


name: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH


name: (4R)-limonene + H(+) + NADH + O2 => H2O + limonene 1,2-epoxide + NAD(+)


name: Mycothiol scavenges nitrosyl (Homo sapiens)


name: ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Danio rerio)


name: glycyl-L-proline(out) + H(+)(out) => glycyl-L-proline(in) + H(+)(in)


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Mus musculus)


name: H2O + quercetin 3-O-beta-D-glucoside = beta-D-glucose + quercetin


name: MAOA:FAD deaminates 3MT to HVA (Rattus norvegicus)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Schizosaccharomyces pombe)


name: L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6)-methyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine


name: SHP2 dephosphorylates Tyr 992 on EGFR (Gallus gallus)


name: PDCL promotes G-protein beta 5 folding (Gallus gallus)


name: Detection of damage during initiation of DNA synthesis in S-phase (Gallus gallus)


name: MUC20 binds MET and inhibits GRB2 binding (Rattus norvegicus)


name: IL31:IL31RA:JAK1 binds OSMR:JAK1 (Rattus norvegicus)


name: PLC-gamma binds to the active receptor (Mus musculus)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Canis familiaris)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 A <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 AH2


name: p-S363,S380,T573 RS6K translocates to the nucleus (Schizosaccharomyces pombe)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Canis familiaris)


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Caenorhabditis elegans)


name: IRAK1 phosphorylates Pellino (Rattus norvegicus)


name: AH2 + chrodrimanin C => 3-hydroxypentacecilide A + A


name: rifampicin ortho-naphthoquinone carboxamide = rifampicin para-naphthoquinone carboxamide


name: (2E,6E)-farnesyl diphosphate + L-cysteinyl-[protein] <=> diphosphate + S-(2E,6E)-farnesyl-L-cysteinyl-[protein]


name: glyoxylate + pyruvate => (4R)-4-hydroxy-2-oxoglutarate


name: (22R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (22R,7alpha)-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1D-myo-inositol 3,4-bisphosphate + H2O => 1D-myo-inositol 3-phosphate + phosphate


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Caenorhabditis elegans)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Caenorhabditis elegans)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: benzylthiol + NH4(+) + pyruvate => H2O + S-benzyl-L-cysteine


name: ATP + L-glutamate + N(6)-hydroxy-L-lysine => 1-L-glutamo-2-N(6-)L-lysinohydrazine + AMP + diphosphate + 2 H(+)


name: Cleavage of Procaspase-7 by the apoptosome (Bos taurus)


name: 2 oxidized [2Fe-2S]-[ferredoxin] + reduced coenzyme F420-(gamma-L-Glu)(n) = 3 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin]


name: "coenzyme F420 oxidoreductase (ferredoxin)"


name: 3-(all-trans-decaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine => 2-methoxy-6-(all-trans-decaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: Internalization of gap junction plaques (Canis familiaris)


name: a penicillin + H2O => 6-aminopenicillanate + a carboxylate


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Drosophila melanogaster)


name: KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Saccharomyces cerevisiae)


name: UCHL5 binds INO80 complex (Canis familiaris)


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Rattus norvegicus)


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Saccharomyces cerevisiae)


name: 2-aminocyclohexanol + H2O + NAD(+) => 2-hydroxycyclohexan-1-one + H(+) + NADH + NH4(+)


name: Autophosphorylation of PKC-theta (Drosophila melanogaster)


name: a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol => a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: NADP(+) + pentan-3-one <=> H(+) + NADPH + pent-1-en-3-one


name: (R)-adrenaline(out) + 2 H(+)(in) => (R)-adrenaline(in) + 2 H(+)(out)


name: butanoyl-[ACP] + NAD(+) => (2E)-butenoyl-[ACP] + H(+) + NADH


name: H2O + neurotensin => L-isoleucyl-L-leucine + neurotensin(1-11)


name: UMPS dimer decarboxylates OMP to UMP (Dictyostelium discoideum)


name: (2E)-octadecenoyl-CoA + H2O => 3-hydroxyoctadecanoyl-CoA


name: (E)-cinnamate + H(+) + NADH => 3-phenylpropanoate + NAD(+)


name: (2E)-geranyl diphosphate + 4-hydroxybenzoate <=> 3-geranyl-4-hydroxybenzoate + diphosphate


name: UDP-alpha-D-xylose(out) + UMP(in) => UDP-alpha-D-xylose(in) + UMP(out)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Danio rerio)


name: 3'-dephospho-CoA(in) + AMP(out) => 3'-dephospho-CoA(out) + AMP(in)


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Bos taurus)


name: 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate => 7-carboxy-7-deazaguanine + ATP + NH4(+)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Homo sapiens)


name: L-alanine(in) + L-methionine(out) => L-alanine(out) + L-methionine(in)


name: FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => 1-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoate + O2 = (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-eicosatetraenoate


name: Cytosolic PLK1 translocates to the nucleus (Saccharomyces cerevisiae)


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Gallus gallus)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Drosophila melanogaster)


name: (1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] <=> (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: 6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate = (2S)-3-sulfolactaldehyde + D-fructose 6-phosphate


name: acetoacetate(out) + H(+)(out) = acetoacetate(in) + H(+)(in)


name: H2O + N-(9Z-octadecenoyl)-L-tyrosine = (9Z)-octadecenoate + L-tyrosine


name: IL21:IL21R:JAK1 binds IL2RG:JAK3 (Sus scrofa)


name: Activated FGFR4 phosphorylates FRS3 (Xenopus tropicalis)


name: 3-aminohexane + H2O + NADP(+) => H(+) + hexan-3-one + NADPH + NH4(+)


name: Formation of HIF:CBP:p300 complex at promoters (Sus scrofa)


name: RBBP4 gene expression is inhibited by E2F6 (Homo sapiens)


name: CK2:FACT phosphorylates TP53 (Bos taurus)


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Rattus norvegicus)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Sus scrofa)


name: 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine => 5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine


name: PKC phosphorylates sphingosine kinase 1 (Saccharomyces cerevisiae)


name: gentamicin X2 + methylcob(III)alamin + S-adenosyl-L-methionine => 5'-deoxyadenosine + cob(III)alamin + geneticin + L-methionine


name: SRC phosphorylates InlA-bound CDH1 and CTNNB1 (Homo sapiens)


name: H2O + N(4)-acetylcytidine => acetate + cytidine + H(+)


name: Degradation of ubiquitinated SMAD2 (Canis familiaris)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Danio rerio)


name: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + isopentenyl diphosphate + phosphate


name: HMGCR dimer binds statins (Schizosaccharomyces pombe)


name: ATP + H(+) + IC-asc-C9 => diphosphate + IC-asc-C9-AMP


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Xenopus tropicalis)


name: (9Z)-octadecen-1-ol + 1-hexadecanoylglycerone 3-phosphate <=> 1-O-(9Z)-octadecenylglycerone 3-phosphate + H(+) + hexadecanoate


name: Diacylgycerol activates Protein kinase C, alpha type (Schizosaccharomyces pombe)


name: fenuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 1-methyl-3-phenylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 1,4-diguanidinobutane + H2O = agmatine + urea


name: Phosphorylation of IFNGR1 by JAK kinases (Mus musculus)


name: MECP2 binds DLL1 gene promoter (Homo sapiens)


name: sulfate(in) + sulfite(out) => sulfate(out) + sulfite(in)


name: N(7)-methylguanosine(1405) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(1405) in 16S rRNA + S-adenosyl-L-methionine


name: H2O2 + pyridine = H2O + pyridine N-oxide


name: all-trans-4-oxoretinoate + UDP-alpha-D-glucuronate <=> all-trans-4-oxoretinoate 1-O-(beta-D-glucuronate) + UDP


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Schizosaccharomyces pombe)


name: a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H2O => a 5'-end dephospho-2'-deoxyribonucleoside-DNA + phosphate


name: a 7(1)-hydroxybacteriochlorophyllide d + H2O + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide d + H(+) + L-methionine


name: deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Rattus norvegicus)


name: H(+)(out) + phosphate(out) => H(+)(in) + phosphate(in)


name: glycine betaine(in) + Na(+)(in) => glycine betaine(out) + Na(+)(out)


name: CDC42:GTP binds CBL:Beta-Pix (Rattus norvegicus)


name: Synthesis of dolichyl-phosphate-glucose (Rattus norvegicus)


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Xenopus tropicalis)


name: 2,5-dihydroxybenzoyl-CoA + H2O = 2,5-dihydroxybenzoate + CoA + H(+)


name: PXLP-K56-SRR dimer deaminates D-Ser (Caenorhabditis elegans)


name: anthranilate + FADH2 + O2 <=> 3-hydroxyanthranilate + FAD + H(+) + H2O


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Drosophila melanogaster)


name: dimethylallyl diphosphate + tardioxopiperazine A = diphosphate + variecolorin L


name: PP1 binds to phosphorylated TIM in complex with PER (Drosophila melanogaster)


name: TCR complex interacts with peptide antigen-presenting MHC Class I (Gallus gallus)


name: D-ribulose 5-phosphate + L-tyrosine => (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + formaldehyde + H(+) + H2O + hydroxyacetone + phosphate


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Bos taurus)


name: LUM (lumican) binds integrin alpha2beta1 (Xenopus tropicalis)


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Schizosaccharomyces pombe)


name: 4alpha-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: (2E,6E)-farnesyl diphosphate => (3E,6E)-alpha-farnesene + diphosphate


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Schizosaccharomyces pombe)


name: Activated FGFR4 mutants bind PLCG1 (Homo sapiens)


name: ARRB mediates NOTCH1 ubiquitination (Homo sapiens)


name: D-glucurono-6,2-lactone + H2O = D-glucuronate + H(+)


name: GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Bos taurus)


name: (2R)-hydroxytetradecanoate + H2O => H2O2 + tetradecanoate


name: (9Z)-hexadecenoate + 5-hydroxy-octadecanoate + H(+) => 5-(9Z-hexadecenoyloxy)-octadecanoate + H2O


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Drosophila melanogaster)


name: Ubiquitination of stimulated EGFR (CBL) (Gallus gallus)


name: 2 H2O2 + Reactive Blue 5 => 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H(+) + 2 H2O + phthalate


name: 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] => 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Mus musculus)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Homo sapiens)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Dictyostelium discoideum)


name: EPH receptors autophosphorylate (Rattus norvegicus)


name: C-ter TLR7 dimer binds HCQ (Rattus norvegicus)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Saccharomyces cerevisiae)


name: a long-chain fatty aldehyde + H2O + NAD(+) = a long-chain fatty acid + 2 H(+) + NADH


name: 4-methylaminobutanal + H2O2 + NH4(+) => H2O + N-methylputrescine + O2


name: RAC2 binds effectors at the phagocytic vesicle membrane (Xenopus tropicalis)


name: Thrombin-activated PARs:G12/13 (active) dissociate (Xenopus tropicalis)


name: CYCS:APAF1 binds procaspase-9 (Danio rerio)


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Sus scrofa)


name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA (Danio rerio)


name: (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase] = (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Mus musculus)


name: FURIN translocates to the plasma membrane (Plasmodium falciparum)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Sus scrofa)


name: ACER2 hydrolyzes ceramide (Golgi) (Caenorhabditis elegans)


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Drosophila melanogaster)


name: (15Z)-tetracosenamide + H2O = (15Z)-tetracosenoate + NH4(+)


name: A + ethylbenzene + H2O = (S)-1-phenylethanol + AH2


name: N(pros)-phospho-L-histidyl-[protein] + N,N'-diacetylchitobiose(out) = diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein]


name: 4alpha-carboxyzymosterol + 6 Fe(III)-[cytochrome b5] + 4 H2O => 4alpha-methylzymosterol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Drosophila melanogaster)


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Drosophila melanogaster)


name: A + a 1-hydroxy-3-oxo steroid <=> a steroid 1,3-dione + AH2


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O => 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + choline + H(+)


name: an N-acylsphing-4-enine + dTDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + dTDP + H(+)


name: fibroblast growth factor receptor antagonist activity


name: MIB2 ubiquitinates CYLD at K338, K530 (Drosophila melanogaster)


name: STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Sus scrofa)


name: D-histidine(in) + H(+)(in) + L-ornithine(out) = D-histidine(out) + H(+)(out) + L-ornithine(in)


name: (R)-2-hydroxytetracosanoate + 2 Fe(III)-[cytochrome b5] + H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + tetracosanoate


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) => 5,6,7,8-tetrahydromethanopterin + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: Gq activation by TP receptor (Mus musculus)


name: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH


name: Disassembly of tight junctions (Caenorhabditis elegans)


name: steviolbioside + UDP-alpha-D-glucose <=> H(+) + rebaudioside B + UDP


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Drosophila melanogaster)


name: Phosphorylation and release of IRF3 (Gallus gallus)


name: beta-D-Delta(4)-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O => 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: 3-methyl-2-oxobutanoate + H2O2 + NH4(+) => H2O + L-valine + O2


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Sus scrofa)


name: protein-RNA sequence-specific adaptor activity


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: OGG1beta translocates to mitochondria (Bos taurus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine => a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H(+) + S-adenosyl-L-homocysteine


name: SUMOylation of MDC1 with SUMO1 (Sus scrofa)


name: 5 H(+)(in) + menaquinone-8 + NADH = 4 H(+)(out) + menaquinol-8 + NAD(+)


name: DHODH:FMN binds DHODH inhibitors (Homo sapiens)


name: PABPN1 binds oligouridylated mRNA (Homo sapiens)


name: GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Mus musculus)


name: [thioredoxin]-dithiol + adenosine 5'-phosphosulfate => [thioredoxin]-disulfide + AMP + 2 H(+) + sulfite


name: H(+) + NADH + uridine(20a) in tRNA => 5,6-dihydrouridine(20a) in tRNA + NAD(+)


name: ATP + H2O + L-alanyl-L-histidine(out) <=> ADP + H(+) + L-alanyl-L-histidine(in) + phosphate


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Canis familiaris)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Dictyostelium discoideum)


name: (2S)-2-amino-4-deoxychorismate + L-glutamate <=> chorismate + L-glutamine


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Caenorhabditis elegans)


name: RAC3 binds effectors at the plasma membrane (Canis familiaris)


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Homo sapiens)


name: AMY1-3 bind pramlintide (Xenopus tropicalis)


name: Transport of MHC heterotrimer to ER exit site (Sus scrofa)


name: adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Bos taurus)


name: H(+) + UDP + vitexin 2''-O-beta-D-glucoside => UDP-alpha-D-glucose + vitexin


name: Growth hormone forms dimers and oligomers (Canis familiaris)


name: Factor Xa inhibitors binds Xa (Danio rerio)


name: Interaction of other tyrosine kinases with p-KIT (Gallus gallus)


name: Recruitment of HDAC1 by p130 (RBL2) (Drosophila melanogaster)


name: ARSB hydrolyses C4S/C6S chains (Canis familiaris)


name: a 3beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid + H(+) + NADH


name: angiotensin-(1-5) + L-histidyl-L-proline => angiotensin-(1-7) + H2O


name: Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Xenopus tropicalis)


name: FMNH2 + nitrilotriacetate + O2 = aminodiacetate + FMN + glyoxylate + H2O


name: prostaglandin G1 => (8Z,11Z,14Z)-eicosatrienoate + 2 O2


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Canis familiaris)


name: Phosphorylated ERF translocates to the cytosol (Rattus norvegicus)


name: 26S proteasome degrades TP73 polyubiquitinated by ITCH (Bos taurus)


name: 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Danio rerio)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Dictyostelium discoideum)


name: G protein-coupled estrogen receptor 1 binds estrogen non-classically (Canis familiaris)


name: STUB1 polyubiquitinates RUNX2 (Mus musculus)


name: ATP binds G-protein beta associated TRiC/CCT (Dictyostelium discoideum)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Xenopus tropicalis)


name: 1-butyrylglycerol + H2O <=> butanoate + glycerol + H(+)


name: 2-phenylethylamine + A + H2O = 2-phenylacetaldehyde + AH2 + NH4(+)


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Canis familiaris)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Sus scrofa)


name: 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-homocysteine => L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-methionine


name: 2-oxoglutarate + gibberellin A9 + O2 = CO2 + gibberellin A4 + succinate


name: decane + O2 + reduced [NADPH--hemoprotein reductase] = 3-decanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Mus musculus)


name: H2O + L-2-amino-4-chloropent-4-enoate => 2-oxopent-4-enoate + chloride + H(+) + NH4(+)


name: P2X7 mediates loss of intracellular K+ (Bos taurus)


name: phosphate(out) + succinate(in) => phosphate(in) + succinate(out)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Danio rerio)


name: chlorophyllide a + 2 H(+) => Mg(2+) + pheophorbide a


name: FASLG (FasL) gene expression (Homo sapiens)


name: H(+) + N(6)-(dimethylallyl)adenosine 5'-diphosphate + NADPH + O2 <=> 9-ribosyl-trans-zeatin 5'-diphosphate + H2O + NADP(+)


name: 2,5-didehydro-D-gluconate + H(+) + NADH <=> 5-dehydro-D-gluconate + NAD(+)


name: MTMR12 binds MTM1 (Dictyostelium discoideum)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Drosophila melanogaster)


name: (E)-non-2-enal + H2O + NAD(+) = (E)-non-2-enoate + 2 H(+) + NADH


name: DPAn-3 resolvins translocate from cytosol to extracellular region (Homo sapiens)


name: benzyl alcohol + CO2 + glycine => H(+) + H2O + N-benzyloxycarbonylglycine


name: CRK,CRKL recruits RAC1 GEF to activated MET (Homo sapiens)


name: SREBP1A,1C,2:Importin beta-1 dissociates (Mus musculus)


name: Activated FGFR3:p-SHC1 binds GRB2:SOS1 (Gallus gallus)


name: 4-hydroxybenzoate + all-trans-nonaprenyl diphosphate <=> 4-hydroxy-3-all-trans-nonaprenylbenzoate + diphosphate


name: (+)-sesamin monocatechol + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) <=> (+)-sesamin dicatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n)


name: PTPN7 binds p-T,Y-MAPK (Saccharomyces cerevisiae)


name: (3S)-3-hydroxybutanoyl-CoA + NADP(+) <=> acetoacetyl-CoA + H(+) + NADPH


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Sus scrofa)


name: deoxybrevianamide E + diphosphate => brevianamide F + dimethylallyl diphosphate


name: NAD(+) + resolvin D2 => 7-oxoresolvin D2 + H(+) + NADH


name: CDH11 associates with catenins (Rattus norvegicus)


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Homo sapiens)


name: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside => L-fucose + methyl beta-D-galactoside


name: NRXNs bind CASK:Protein 4.1 (Drosophila melanogaster)


name: 8-hydroxycopalyl diphosphate <=> cis-abienol + diphosphate


name: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate


name: (9Z)-octadecenoyl-CoA + 3-octadecanoyl-sn-glycerol <=> 1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + CoA


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Plasmodium falciparum)


name: (2S)-2-acetamido-4-aminobutanoate => H2O + L-ectoine


name: 3 Na(+)(out) + selenate(out) <=> 3 Na(+)(in) + selenate(in)


name: MECP2:SIN3A complex binds OPRM1 gene promoter (Homo sapiens)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose <=> beta-D-Gal-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: 9-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 9-hydroxy-octadecanoate + H(+)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O => H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: Dimerization of Phospho-IRF3 (Gallus gallus)


name: Truncated Alpha-1-Microglobulin binds heme (Canis familiaris)


name: Tenascins C, R, (X, N) bind fibronectin matrix (Homo sapiens)


name: (E)-isoeugenol + S-adenosyl-L-methionine => (E)-isomethyleugenol + H(+) + S-adenosyl-L-homocysteine


name: hexadecanoate + L-phenylalanine => H2O + N-hexadecanoyl-L-phenylalanine


name: DHRS7B reduces GO3P to HXDG3P (Caenorhabditis elegans)


name: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => all-trans-4-hydroxyretinol + H2O + 2 oxidized [adrenodoxin]


name: AMP(out) + UMP(in) => AMP(in) + UMP(out)


name: Cleavage of DFF45 (224) by caspase-3 (Rattus norvegicus)


name: a long-chain fatty acid + ATP + H(+) <=> a long-chain fatty acyl-AMP + diphosphate


name: H2O + tuberculosinyl diphosphate => (13S)-edaxadiene + diphosphate


name: "N-terminal methionine N(alpha)-acetyltransferase NatC"


name: SEMA3E binds to PLXND1 (Canis familiaris)


name: MARK3 phosphorylates KSR1 (Mus musculus)


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Danio rerio)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycerol + UDP-alpha-D-galactose = 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP


name: isoorientin + S-adenosyl-L-methionine => H(+) + isoscoparin + S-adenosyl-L-homocysteine


name: a medium chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Gallus gallus)


name: TULP3 is required for GPR161 localization in the cilium (Canis familiaris)


name: GBF1 stimulates nucleotide exchange on ARF (Plasmodium falciparum)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Sus scrofa)


name: dodecanoyl-CoA + O2 <=> (2E)-dodecenoyl-CoA + H2O2


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Rattus norvegicus)


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> a 2-acyl-sn-glycero-3-phosphocholine + H(+) + hexanoate


name: POLK incorporates dNMP opposite to damaged DNA base (Homo sapiens)


name: Hv1 Mediated H+ Permeability (Xenopus tropicalis)


name: TP53 stimulates DDB2 expression (Homo sapiens)


name: SLC2A9 transports Fru, Glc, urate (Sus scrofa)


name: diphosphate + GMP => 5-phospho-alpha-D-ribose 1-diphosphate + guanine


name: NEU1 hydrolyses Neu5Ac from glycoconjugates (Rattus norvegicus)


name: an adenosine in mRNA + S-adenosyl-L-methionine <=> an N(6)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: ULK complex translocates to the ER (Drosophila melanogaster)


name: delta-dodecalactone + H2O => 5-hydroxydodecanoate + H(+)


name: chloride(out) + L-methionine(out) + 2 Na(+)(out) = chloride(in) + L-methionine(in) + 2 Na(+)(in)


name: ERBB4 forms heterodimers with ERBB3 (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = CoA + H(+) + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine


name: acetate:monoatomic cation symporter activity


name: (1S,2R,4S)-borneol + NAD(+) <=> (1S,4S)-camphor + H(+) + NADH


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Canis familiaris)


name: ASIC trimers bind H+ (Rattus norvegicus)


name: RPA binds to the Flap on the C-strand (Sus scrofa)


name: NADP(+) + neomorphine <=> H(+) + NADPH + neomorphinone


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Drosophila melanogaster)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Mus musculus)


name: oxalate transmembrane transporter activity


name: P2Y14 receptor can bind to UDP-glucose (Homo sapiens)


name: RBP3 regulates the transport of atROL from ROS to RPE (Bos taurus)


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Drosophila melanogaster)


name: H(+) + hydrogen sulfide + O-phospho-L-serine => L-cysteine + phosphate


name: AICAR + 10-Formyl-THF => FAICAR + THF (Danio rerio)


name: NFE2L2 dependent ABCF2 expression (Homo sapiens)


name: MAT1A multimers transfer Ado from ATP to L-Met (Schizosaccharomyces pombe)


name: ATP + D-ribose(out) + H2O = ADP + D-ribose(in) + H(+) + phosphate


name: 5alpha-cholest-7-en-3-one + H(+) + NADH => lathosterol + NAD(+)


name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Homo sapiens)


name: GPIb-IX-V binds to vWF:Collagen complex (Mus musculus)


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Sus scrofa)


name: chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] => cholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 6-hydroxy-3-isopropenylheptanoate + H(+) => 4-isopropenyl-7-methyloxepan-2-one + H2O


name: 3-dehydro-4-O-phospho-L-erythronate + H(+) = CO2 + dihydroxyacetone phosphate


name: 5-chloro-L-tryptophan + FAD + 2 H2O => chloride + FADH2 + L-tryptophan + O2


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Gallus gallus)


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (2E)-geranyl diphosphate + isopentenyl diphosphate = (2Z,6E)-farnesyl diphosphate + diphosphate


name: ARSA removes sulfate from SM3 (Bos taurus)


name: (9Z)-octadecenoate + 2-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + H(+) => 1,3-di-(9Z)-octadecenoyl-2-hexadecanoylglycerol + H2O


name: SLC7A3 (CAT-3)-mediated uptake of cationic amino acids (Rattus norvegicus)


name: 4-hydroxybenzoate + all-trans-decaprenyl diphosphate => 4-hydroxy-3-all-trans-decaprenylbenzoate + diphosphate


name: (S)-dihydroorotate + a quinone => a quinol + orotate


name: hexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 26-hydroxyhexacosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PKR inhibitors bind PKR (Caenorhabditis elegans)


name: ABCB4 transports PC from plasma membrane to extracellular region (Mus musculus)


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Danio rerio)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Caenorhabditis elegans)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Canis familiaris)


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Homo sapiens)


name: MIOX oxidises Ins to GlcA (Canis familiaris)


name: Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Xenopus tropicalis)


name: H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Homo sapiens)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH => (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+)


name: (3R,5R)-clavulanate-9-aldehyde + H(+) + NADPH <=> clavulanate + NADP(+)


name: H2O + N-(9Z-octadecenoyl)-L-glutamine <=> (9Z)-octadecenoate + L-glutamine


name: NAD(+) + resolvin E1 = 18-oxo-resolvin E1 + H(+) + NADH


name: 2 H(+) + hexadecanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (6Z)-hexadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Mus musculus)


name: IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Mus musculus)


name: formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase] + phenol => anisole + O2 + reduced [NADH--hemoprotein reductase]


name: 2-hydroxyhexadecanoate + O2 <=> 2-oxohexadecanoate + H2O2


name: SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Gallus gallus)


name: H(+)(out) + L-valine(in) => H(+)(in) + L-valine(out)


name: dodecanoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxotetradecanoyl-[ACP] + CO2 + holo-[ACP]


name: Multiubiquitination of APC/C-associated Cdh1 (Dictyostelium discoideum)


name: Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate (Homo sapiens)


name: a 2,3-saturated acyl-CoA + FAD + H(+) = a (2E)-enoyl-CoA + FADH2


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Homo sapiens)


name: MIR200B/C microRNAs bind NOTCH1 mRNA (Homo sapiens)


name: cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Mus musculus)


name: cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Sus scrofa)


name: 3 A + phytyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + 3 AH2


name: HMG CoA => acetoacetic acid + acetyl CoA (Canis familiaris)


name: PEX3:PEX19:class I PMP dissociates (Saccharomyces cerevisiae)


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-2-acetyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: CD22 binds itself to form homo-oligomers (Sus scrofa)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Saccharomyces cerevisiae)


name: (2E)-15-methylhexadecenoyl-CoA + H(+) + NADPH <=> isoheptadecanoyl-coA + NADP(+)


name: LCAT + spherical HDL <=> LCAT:spherical HDL complex (Mus musculus)


name: a sphingoid base + tetracosanoyl-CoA => an N-tetracosanoyl-sphingoid base + CoA + H(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + xanthotoxin => 5-hydroxyxanthotoxin + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine <=> 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Canis familiaris)


name: 1-tetradecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O => 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Mus musculus)


name: 3 H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine => N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A => 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: [1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose <=> [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + H(+) + UDP


name: Factor H binds to C3bBb (Xenopus tropicalis)


name: Exchange of oxygen with sulfur in MoCo (Caenorhabditis elegans)


name: PLK1 phosphorylates NEK9 (Caenorhabditis elegans)


name: dTDP-6-deoxy-alpha-D-allose + NAD(+) => dTDP-4-dehydro-6-deoxy-alpha-D-allose + H(+) + NADH


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Danio rerio)


name: COX15 transforms heme O to heme A (Xenopus tropicalis)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Gallus gallus)


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Canis familiaris)


name: (9Z)-tetradecenoyl-CoA + AMP + diphosphate => (9Z)-tetradecenoate + ATP + CoA


name: genistein 7-O-beta-D-glucoside + H2O => beta-D-glucose + genistein


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Caenorhabditis elegans)


name: NOX4, NOX5 reduce O2 to O2.- (Canis familiaris)


name: (3S)-3-hydroxybutanoyl-CoA + NAD(+) => acetoacetyl-CoA + H(+) + NADH


name: Spermine  => N-acetylated spermine (Saccharomyces cerevisiae)


name: Methylation of N-acetyl-5-HT to form melatonin (Mus musculus)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyestradiol-17beta + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: pyridoxamine 5'-phosphate + pyruvate => D-alanine + pyridoxal 5'-phosphate


name: CYP1A2 S-demethylates 6MMP (Homo sapiens)


name: holo-[(phenol)carboxyphthiodiolenone synthase] + icosanoyl-AMP = AMP + H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Gallus gallus)


name: 2-methylbutan-1-ol + butanoyl-CoA => 2-methylbutyl butanoate + CoA


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (11R)-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Defective HEXB does not cleave the terminal GalNAc from keratan sulfate (Homo sapiens)


name: p-4Y-SIRPA:CD47 binds PTK2B (Mus musculus)


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Sus scrofa)


name: 2 Fe(III)-[cytochrome c] + S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein]


name: propane-1,3-diamine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + norspermidine + S-methyl-5'-thioadenosine


name: 3 AH2 + ATP + H2O + Ni-sirohydrochlorin a,c-diamide = 15,17(3)-seco-F430-17(3)-acid + 3 A + ADP + phosphate


name: "Ni-sirohydrochlorin a,c-diamide reductive cyclase"


name: 13,14-dihydro-15-oxo-prostaglandin E2 + NADP(+) = 15-oxoprostaglandin E2 + H(+) + NADPH


name: CBL ubiquitinates PI3K (Caenorhabditis elegans)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Homo sapiens)


name: cis-3-hydroxy-L-proline => 1-pyrroline-2-carboxylate + H2O


name: a globoside Gb3Cer + UDP-alpha-D-galactose = a globoside GalGb3Cer + H(+) + UDP


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Homo sapiens)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Danio rerio)


name: Interaction of DAP12 and IREM2 (Rattus norvegicus)


name: CoA + H(+) + N-dodecanoyl-3-oxosphinganine => 3-oxosphinganine + dodecanoyl-CoA


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Xenopus tropicalis)


name: AcK-NFE2L2 binds the ABCC3 gene (Homo sapiens)


name: MST1R autophosphorylates (Caenorhabditis elegans)


name: cGMP is degraded by PDEs (Xenopus tropicalis)


name: SPRY2 translocates to the plasma membrane (Mus musculus)


name: Addition of galactose to Core 6 glycoprotein (Rattus norvegicus)


name: Cleavage of uracil by SMUG1 glycosylase (Mus musculus)


name: BLVRA:Zn2+, BLVRB reduce BV to BIL (Mus musculus)


name: 2',3'-cyclophospho-AMP + H2O => 3'-AMP + H(+)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Bos taurus)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Danio rerio)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Danio rerio)


name: ERK1/2 phosphorylates MSK1 (Mus musculus)


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Danio rerio)


name: LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (Homo sapiens)


name: H2O + NADP(+) + rifamycin SV para-naphthoquinone carboxamide => NADPH + O2 + rifamycin SV


name: atROL binds RBP1 to form RBP1:atROL (Canis familiaris)


name: H2O + L-valine + O2 <=> 3-methyl-2-oxobutanoate + H2O2 + NH4(+)


name: Exocytosis of azurophil granule membrane proteins (Rattus norvegicus)


name: CYP24A1 24-hydroxylates CTL (Sus scrofa)


name: hydroquinone O-beta-D-glucopyranoside(in) => hydroquinone O-beta-D-glucopyranoside(out)


name: D-cellotetraose + O2 => D-cellotetraono-1,5-lactone + H2O2


name: spermidine:sinapoyl CoA N-acyltransferase activity


name: Displacement of MPG glycosylase by APEX1 at the AP site (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Xenopus tropicalis)


name: (2E)-5-methylhexenoyl-[ACP] + H(+) + NADH => 5-methylhexanoyl-[ACP] + NAD(+)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycerol <=> 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Sus scrofa)


name: p-T,Y MAPKs dimerize (Plasmodium falciparum)


name: ASC binds Caspase-8 complex (Bos taurus)


name: S1P binds S1PR3 in response to E2 stimulation (Gallus gallus)


name: H(+) + N(1)-methyladenosine(645) in 25S rRNA + S-adenosyl-L-homocysteine => adenosine(645) in 25S rRNA + S-adenosyl-L-methionine


name: 3-O-methylgallate + O2 = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + methanol


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Sus scrofa)


name: (6Z,9Z,12Z)-octadecatrienoate + H2O = (10S)-hydroxy-(6Z,12Z)-octadecadienoate


name: SUMOylation of PCNA with SUMO1 (Rattus norvegicus)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate <=> 3-hydroxypent-4-ene nitrile + sulfate + sulfur


name: adenosine(out) + Na(+)(out) = adenosine(in) + Na(+)(in)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Mus musculus)


name: 2-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + glycerol + H(+)


name: POU5F1 (OCT4), SOX2, NANOG bind the EOMES promoter (Homo sapiens)


name: acetyl-[ACP] + CO2 => H(+) + malonyl-[ACP]


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Xenopus tropicalis)


name: Activated FGFR2 binds FRS2 (Mus musculus)


name: a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: 5D-5-O-methyl-chiro-inositol + NADP(+) <=> 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH


name: an N-acyl-L-homoserine + H(+) => an N-acyl-L-homoserine lactone + H2O


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Bos taurus)


name: Abortive initiation after formation of the first phosphodiester bond (Mus musculus)


name: Parkin transfers Ub to misfolded proteins (Drosophila melanogaster)


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: H(+) + NADH + pyruvate => (R)-lactate + NAD(+)


name: decanoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = dec-9-enoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: RAC2 GEFs activate RAC2 (Dictyostelium discoideum)


name: glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate (Gallus gallus)


name: a globoside NOR2 + H(+) + UDP => a globoside NORint + UDP-alpha-D-galactose


name: Cdt1 is displaced from the pre-replicative complex. (Gallus gallus)


name: D-mannitol 1-phosphate(in) + L-histidyl-[protein] => D-mannitol(out) + N(pros)-phospho-L-histidyl-[protein]


name: MECP2 mRNA translation is inhibited by miR-132 (Homo sapiens)


name: 2-methylpropan-1-amine + H2O + NAD(+) <=> 2-methylpropanal + H(+) + NADH + NH4(+)


name: cAMP-dependent protein kinase regulator activity


name: 2-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoate + L-tryptophan => H2O + N-(9Z-octadecenoyl)-L-tryptophan


name: SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Sus scrofa)


name: EDNRA binds selective ERAs (Xenopus tropicalis)


name: 5,6-dihydrouridine(17) in tRNA + NADP(+) => H(+) + NADPH + uridine(17) in tRNA


name: (3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl-[ACP] + AH2 + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine => 6-[(3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl]-2,4-dihydroxy-3-methylbenzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP] + S-adenosyl-L-homocysteine


name: Formation of PRC2-EZH2 complex (Rattus norvegicus)


name: 9H-fluoren-9-ol + NAD(+) <=> 9H-fluoren-9-one + H(+) + NADH


name: D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+) = diphosphate + GDP-D-glycero-alpha-D-manno-heptose


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)


name: LONP1 binds mitochondrial matrix proteins (Canis familiaris)


name: S-adenosyl-L-methionine + squalene => 3-methyl-1,2-didehydro-2,3-dihydrosqualene + H(+) + S-adenosyl-L-homocysteine


name: MMAA:MUT binds AdoCbl (Canis familiaris)


name: bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE (Canis familiaris)


name: 3-oxoisoheptadecanoyl-CoA + H(+) + NADPH => 3-hydroxyisoheptadecanoyl-CoA + NADP(+)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Caenorhabditis elegans)


name: CASP9 is phosphorylated at T412 (Gallus gallus)


name: (E)-6-(methylsulfanyl)hexanal oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-trihomomethionine


name: 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + AH2 + O2 = 3-demethylubiquinol-8 + A + H2O


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Xenopus tropicalis)


name: PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Homo sapiens)


name: Interaction of PAK1 with Rac1-GTP (Rattus norvegicus)


name: 3-oxalomalate <=> glyoxylate + oxaloacetate


name: H2O + hypoxanthine + O2 => H2O2 + xanthine


name: H2O + phosphoethanolamine <=> ethanolamine + phosphate


name: PON1,3 hydrolyse ATVL to ATV (Bos taurus)


name: a sphingomyelin + H2O <=> a carboxylate + sphing-4-enine-phosphocholine


name: HRASLS transfer acyl group from PC to PE to form NAPE (Sus scrofa)


name: MPI isomerises Fru6P to Man6P (Danio rerio)


name: hexanoyl-CoA + O2 <=> (2E)-hexenoyl-CoA + H2O2


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Mus musculus)


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate


name: cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 <=> albonoursin + H2O2


name: H(+) + NADH + ubiquinone-8 => NAD(+) + ubiquinol-8


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Canis familiaris)


name: 2-(9Z,12Z-octadecadienoyl)-glycerol + H2O <=> (9Z,12Z)-octadecadienoate + glycerol + H(+)


name: FGFR1c binds to Klotho-bound FGF23 (Sus scrofa)


name: Activation of Potassium transport channels (Mus musculus)


name: DMGLY translocates from cytosol to mitochondrial matrix (Homo sapiens)


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Xenopus tropicalis)


name: UBQLNs bind UIM-containing adaptor proteins (Bos taurus)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Canis familiaris)


name: SEMA4D interacts with Plexin-B1:ErbB2 (Rattus norvegicus)


name: GLI1 is degraded by the proteasome after ubiquitination by ITCH (Sus scrofa)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Caenorhabditis elegans)


name: all-trans-4,4'-diaponeurosporene + FADH2 => all-trans-4,4'-diapo-zeta-carotene + FAD + H(+)


name: desacetylmycothiol is acetylated to mycothiol using acetyl-CoA (Mycobacterium tuberculosis)


name: (2E)-2-hydroxypenta-2,4-dienoate + anthranilate + H(+) => (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O


name: Proteasomal cleavage of substrate (Saccharomyces cerevisiae)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Dictyostelium discoideum)


name: (E)-cinnamate + NH4(+) => L-phenylalanine


name: 3-oxocholan-24-oyl-CoA + NAD(+) => 3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: (2E)-butenoyl-CoA + H2O2 => butanoyl-CoA + O2


name: PRMT1 arginine-methylates RUNX1 (Canis familiaris)


name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Rattus norvegicus)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Mus musculus)


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Sus scrofa)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Drosophila melanogaster)


name: ARMS is phosphorylated by active TrkA receptor (Homo sapiens)


name: SeO3(2-) combines with GSH to form GSSeSG and GSSG (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: cortisol + H(+) + NADPH => 5beta-dihydrocortisol + NADP(+)


name: PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Mus musculus)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Plasmodium falciparum)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CD200 binds to CD200R (Xenopus tropicalis)


name: Oxidation of cholesterol to 22beta-hydroxycholesterol (Rattus norvegicus)


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Homo sapiens)


name: ORC2 binds ORC3 (Schizosaccharomyces pombe)


name: all-trans-heptaprenyl diphosphate <=> (R)-tetraprenyl-beta-curcumene + diphosphate


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Bos taurus)


name: (2Z,6Z)-farnesyl diphosphate <=> beta-acoradiene + diphosphate


name: ATP + oleandomycin <=> ADP + H(+) + oleandomycin 2'-O-phosphate


name: 4,8-dimethylnonanoyl-CoA + H2O => adenosine 3',5'-bisphosphate + 2 H(+) + S-(4,8-dimethylnonanoyl)-4'-phosphopantetheine


name: Autocatalytic phosphorylation of FGFR4 (Rattus norvegicus)


name: Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding (Homo sapiens)


name: 6-azauridine + ATP => 6-azauridine 5'-phosphate + ADP + H(+)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Caenorhabditis elegans)


name: 2-oxoglutarate(in) + urate(out) => 2-oxoglutarate(out) + urate(in)


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Homo sapiens)


name: citrate(out) + phosphoenolpyruvate(in) <=> citrate(in) + phosphoenolpyruvate(out)


name: H(+) + L-methionyl(44)-[F-actin] + NADPH + O2 <=> H2O + L-methionyl(44)-(R)-S-oxide-[F-actin] + NADP(+)


name: Cytosolic DUSPs dephosphorylate MAPKs (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate


name: (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate + 2 H(+) + NADH => 2-hydroxy-5-carboxymethylmuconate semialdehyde + H2O + NAD(+)


name: 2'-hydroxyformononetin + 2 H(+) + NADPH => (3R)-vestitone + NADP(+)


name: OCT1 transports organic cations out of hepatic cells (Homo sapiens)


name: 1,4-cineole + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-exo-hydroxy-1,4-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Homo sapiens)


name: MAOA:FAD oxidatively deaminates of 5HT (Mus musculus)


name: ATP + glutathione + spermidine = ADP + glutathionylspermidine + H(+) + phosphate


name: erythritol + NADP(+) => D-erythrose + H(+) + NADPH


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Rattus norvegicus)


name: ABCB11 transports bile salts from cytosol to extracellular region (Homo sapiens)


name: NaS1 co-transports sulphate and a sodium ion (Mus musculus)


name: diisopropyl fluorophosphate + H2O <=> diisopropyl phosphate + fluoride + 2 H(+)


name: dimethyl sulfide + S-adenosyl-L-methionine => S-adenosyl-L-homocysteine + trimethylsulfonium


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Caenorhabditis elegans)


name: dodecanamide + H2O = dodecanoate + NH4(+)


name: IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)


name: ALDH1A1 oxidises GA to DGA (Rattus norvegicus)


name: Transfer of NEDD8 to AcM-UBE2F (Canis familiaris)


name: Type B histone acetlytransferase complex acetylates histone H4 (Rattus norvegicus)


name: phycocyanobilin-L-cysteinyl(84)-[allophycocyanin beta-subunit] = (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[allophycocyanin beta-subunit]


name: 2-oxoglutarate + an N(6)-methyladenosine in mRNA + O2 = an adenosine in mRNA + CO2 + formaldehyde + succinate


name: PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser (Plasmodium falciparum)


name: IMPDH tetramers binds IMPDH inhibitors (Sus scrofa)


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Schizosaccharomyces pombe)


name: S100A8:S100A9 binds TLR4:LY96 (Canis familiaris)


name: AFG3L2 binds mitochondrial matrix proteins (Gallus gallus)


name: a 16alpha-hydroxysteroid + NAD(+) <=> a 16-oxosteroid + H(+) + NADH


name: H(+) + octadecanoate + sn-glycerol 3-phosphocholine => 1-octadecanoyl-sn-glycero-3-phosphocholine + H2O


name: docosanoyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> AMP + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + H(+)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Homo sapiens)


name: (20S)-protopanaxadiol + O2 + reduced [NADPH--hemoprotein reductase] = (20S)-protopanaxatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Drosophila melanogaster)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Rattus norvegicus)


name: Syndecan-1 binds Integrin alphaVBeta5 (Homo sapiens)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Bos taurus)


name: 2 H(+) + NADH + neurosporaxanthin => 4'-apo-beta-carotenal + H2O + NAD(+)


name: protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity


name: 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + H(+) + NADPH <=> 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-4H,6H,7H,8H-pyrrolo[1,2-a]pyrazine + NADP(+)


name: Receptor CCR6 binds CCL20 ligand (Gallus gallus)


name: IMPAD1 hydrolyses PAP to AMP (Danio rerio)


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: DNA polymerase alpha:primase binds at the origin (Gallus gallus)


name: Phosphorylated SMAD2/3 dissociates from TGFBR (Mus musculus)


name: Trafficking of GluR1-containing  AMPA receptors (Mus musculus)


name: Cannabinoid receptors can bind cannabinoids (Canis familiaris)


name: AURKB phosphorylates TP53 (Mus musculus)


name: a ganglioside GD1b + H2O => a ganglioside GM1 + N-acetylneuraminate


name: a 2-demethylmenaquinol + S-adenosyl-L-methionine => a menaquinol + H(+) + S-adenosyl-L-homocysteine


name: PIAS1 SUMOylates L3MBTL2 with SUMO2 (Rattus norvegicus)


name: (2S)-naringenin 4',7-dimethyl ether + O2 + reduced [NADPH--hemoprotein reductase] <=> (2S)-carthamidin-4',7-dimethyl ether + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (R)-nephthenol + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Canis familiaris)


name: Phosphorylation of APC component of the destruction complex (Mus musculus)


name: ASIC trimers:H+ transport extracellular Na+ to cytosol (Sus scrofa)


name: mannosylglycerate transmembrane transporter activity


name: E2F6 binds RBBP8 gene promoter (Homo sapiens)


name: H2O + N-acetyl-beta-D-muramate 6-phosphate = (R)-lactate + N-acetyl-beta-D-glucosamine 6-phosphate


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Mus musculus)


name: chenodeoxycholate + octyl beta-D-glucose = beta-D-glucosyl-(1->3)-O-chenodeoxycholate + octan-1-ol


name: 5-hexenoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: an all-trans-retinyl ester + H2O => 13-cis-retinol + a fatty acid + H(+)


name: dihydrocurcumin + NADP(+) => curcumin + H(+) + NADPH


name: a 5-methylcytidine in 25S rRNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in 25S rRNA + S-adenosyl-L-methionine


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Sus scrofa)


name: BIL dissociates from GSTA1, FABP1 (Canis familiaris)


name: H2O + xanthoaphin => protoaphin aglucone


name: NADH + O2 + rifamycin SV => H2O + NAD(+) + rifamycin SV para-naphthoquinone carboxamide


name: 20S,23-dihydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 20S,23,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: 4-isopropylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 4-isopropylphenol


name: (2R,4S)-2,4-diaminopentanoate + H2O + NADP(+) => (2R)-2-amino-4-oxopentanoate + H(+) + NADPH + NH4(+)


name: 2-hydroxyhexanoyl-CoA + CO2 + succinate => 2-oxoglutarate + hexanoyl-CoA + O2


name: 2 Fe(2+) + 4 H2O + O2 = 6 H(+) + H2O2 + 2 iron(III) oxide-hydroxide


name: 15alpha-stemmadenine intermediate II + NADP(+) => 15alpha-stemmadenine intermediate I + NADPH


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Mus musculus)


name: [collagen]-L-lysyl-N-S-L-methionyl-[collagen] + bromide + H(+) + H2O => hypobromite + L-lysyl-[collagen] + L-methionyl-[collagen]


name: myricetin + S-adenosyl-L-methionine = 3-O-methylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: Translocation of active Cdc25C to the nucleus (Saccharomyces cerevisiae)


name: (3R)-3-hydroxy-D-aspartate = glycine + glyoxylate


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Rattus norvegicus)


name: 3,5,6-trichloropyridin-2-ol + FADH2 + O2 <=> 3,6-dichloropyridine-2,5-dione + chloride + FAD + 2 H(+) + H2O


name: 19-hydroxyandrost-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] => 19-oxo-androst-4-ene-3,17-dione + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: adenosine(37) in tRNA(Ala) + H(+) + H2O => inosine(37) in tRNA(Ala) + NH4(+)


name: 2-oxoglutarate + 2 H(+) + NADPH => 2,5-dioxopentanoate + H2O + NADP(+)


name: Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 (Homo sapiens)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Danio rerio)


name: IMPDH tetramers binds IMPDH inhibitors (Dictyostelium discoideum)


name: (13R)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O => (9Z,12Z)-octadecadienoate + AH2 + O2


name: 3beta-hydroxycostunolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase]


name: Fibrillin-1 binds integrins (Danio rerio)


name: (5Z)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2 H(+) + hexanedioate + NADPH => 6-oxohexanoate + H2O + NADP(+)


name: eNoSC deacetylates histone H3 (Saccharomyces cerevisiae)


name: SMPD4 hydrolyzes sphingomyelin (ER membrane) (Danio rerio)


name: (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + CO2 + CoA


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + H2O


name: (R)-2-hydroxyoctadecanoate + NAD(+) <=> 2-oxooctadecanoate + H(+) + NADH


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Dictyostelium discoideum)


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Rattus norvegicus)


name: Integrator complex processes the 3' end of snRNA (Sus scrofa)