name: butanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]


name: Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Bos taurus)


name: acetyl-CoA + N-terminal L-methionyl-L-tryptophyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-tryptophyl-[protein]


name: (+)-6-hydroxypinoresinol + 2 H(+) + 2 reduced [azurin] => (+)-pinoresinol + H2O + 2 oxidized [azurin]


name: a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)


name: SREBP1A,2 binds the LSS promoter (Homo sapiens)


name: GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)


name: (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-corytuberine + 2 H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Sus scrofa)


name: adenosine 5'-phosphosulfate + phosphate => 3'-phosphoadenylyl sulfate + H2O


name: 2 A + a carotenoid beta-end derivative => a carotenoid chi-end derivative + 2 AH2


name: Caspase mediated cleavage of alpha-II-Fodrin (Caenorhabditis elegans)


name: Binding of IP3 to IP3 receptor (Rattus norvegicus)


name: Phosphorylation of Syntaxin-4 (Rattus norvegicus)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Homo sapiens)


name: H2O + L-aspartate + O2 = H2O2 + NH4(+) + oxaloacetate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O


name: miR-205 microRNA binds PTEN mRNA (Homo sapiens)


name: glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Bos taurus)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 <=> 4-[(E)-2-isocyanoethenyl]phenol + 2 CO2 + H2O + succinate


name: WNT5A binds FZD and ROR receptors (Rattus norvegicus)


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Drosophila melanogaster)


name: (S)-methylmalonyl-CoA + H(+) => CO2 + propanoyl-CoA


name: C4b binding protein binds Protein S (Homo sapiens)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Saccharomyces cerevisiae)


name: NLK translocates to nucleus (Schizosaccharomyces pombe)


name: COX10 transforms heme to heme O (Mus musculus)


name: KCNJ11:ABCC9 binds nicorandil (Canis familiaris)


name: ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 (Canis familiaris)


name: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH


name: H(+) + menaquinol-12 + S-adenosyl-L-homocysteine => 2-demethylmenaquinol-12 + S-adenosyl-L-methionine


name: MET receptor dimerizes (Xenopus tropicalis)


name: RIC1:RGP1 recruits RAB6:GDP to the TGN (Saccharomyces cerevisiae)


name: Myristoylation of tBID by NMT1 (Danio rerio)


name: 2xTPK1:Mg2+ phosphorylates THMN (Xenopus tropicalis)


name: aclacinomycin T + dTDP + 2 H(+) => aklavinone + dTDP-beta-L-rhodosamine


name: Rnd1 interacts with Plexin-B1:Sema4D (Rattus norvegicus)


name: 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 H2O => 2 AMP + ATP + 2 H(+)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Sus scrofa)


name: PHLPP dephosphorylates S473 in AKT (Drosophila melanogaster)


name: 2-methylpropanal + CO2 => 3-methyl-2-oxobutanoate + H(+)


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Canis familiaris)


name: Met1-linked polyubiquitin deubiquitinase activity


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Homo sapiens)


name: p62 is recruited and forms a complex with TRAF6 (Canis familiaris)


name: 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH => 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Xenopus tropicalis)


name: Ligand-independent dimerization of KIT extracellular domain mutants (Homo sapiens)


name: GLB1 hydrolyses a glycosaminoglycan (Caenorhabditis elegans)


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Rattus norvegicus)


name: FUT1,2 transfer fucose to gangliosides (Rattus norvegicus)


name: Melanocortin receptors bind melanocortins (Rattus norvegicus)


name: Activated calmodulin dissociates from CaMKII-gamma (Homo sapiens)


name: Activation of STAT5a/b by JAK2 (Sus scrofa)


name: p-Y389,400-RUFY1 binds PI3P (Bos taurus)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Canis familiaris)


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Canis familiaris)


name: a nitrile + H2O => an aliphatic aldoxime


name: 15-cis-4,4'-diapophytoene + 3 FAD + 3 H(+) => all-trans-4,4'-diaponeurosporene + 3 FADH2


name: Abortive Initiation Before Second Transition (Dictyostelium discoideum)


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Mus musculus)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Bos taurus)


name: RAS GAPs stimulate RAS GTPase activity (Drosophila melanogaster)


name: (d)ADP + ADP <=> (d)AMP + ATP (AK1) (Caenorhabditis elegans)


name: KCNJs transport K+ from the extracellular region to cytosol (Danio rerio)


name: ADP + an N(4)-acetylcytidine in 18S rRNA + CoA + H(+) + phosphate => a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O


name: Phosphorylation of PD-1 (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) <=> 3alpha-hydroxyetiocholan-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: Pellino ubiquitinates IRAK1 (Sus scrofa)


name: (E)-feruloyl-CoA + tyramine <=> CoA + H(+) + N-[(E)-feruloyl]tyramine


name: CO + CoA + methyl-Co(III)-[corrinoid Fe-S protein] => acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+)


name: DeMQ10H2 is methylated to Q10H2 by COQ3 (Plasmodium falciparum)


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Rattus norvegicus)


name: FPGS-2 transforms THF to THFPG (Canis familiaris)


name: 3-[[[(2R,3R)-3-carboxyoxiran-2-yl]carbonyl]amino]-L-alanine + ATP + L-valine <=> ADP + dapdiamide E + H(+) + phosphate


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Bos taurus)


name: OPLAH hydrolyses OPRO to L-Glu (Caenorhabditis elegans)


name: Recruitment of ZAP-70 to phosphorylated ITAMs (Gallus gallus)


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Saccharomyces cerevisiae)


name: benzoyl-CoA + octan-1-ol = CoA + octyl benzoate


name: BAP1 binds BAP1-interacting complex (Sus scrofa)


name: protein-phosphocysteine-mannitol phosphotransferase system transporter activity


name: H2O + N-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = H(+) + N-(9Z-octadecenoyl) ethanolamine + sn-glycerol 3-phosphate


name: PDE6D dissociates from ARL13B:INPP5E (Canis familiaris)


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Plasmodium falciparum)


name: oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor


name: diglucosyl-enterobactin + H(+) + UDP => monoglucosyl-enterobactin + UDP-alpha-D-glucose


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate = ectocarpin C


name: Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Mus musculus)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Gallus gallus)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Mus musculus)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Caenorhabditis elegans)


name: p-T,Y-MAPK8 translocates from the cytosol to the nucleoplasm (Homo sapiens)


name: 2 (3R)-3-isocyanylbutanoyl-[ACP] + ATP + L-lysine + 2 NADPH <=> (2S)-2,6-bis[(3R)-3-isocyanobutanamido]hexan-1-ol + AMP + diphosphate + 2 holo-[ACP] + 2 NADP(+)


name: cyanidin + UDP-alpha-D-galactose => cyanidin 3-O-beta-D-galactoside + H(+) + UDP


name: ADP + gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + H(+) + phosphate => ATP + L-glutamate + L-glutamyl-[beta-tubulin]


name: dopamine + 2 L-ascorbate + O2 => (R)-noradrenaline + H2O + 2 monodehydro-L-ascorbate radical


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Bos taurus)


name: Kazrin binds periplakin (Canis familiaris)


name: (2E,4E)-hexadienoyl-CoA + H(+) + NADPH = (3E)-hexenoyl-CoA + NADP(+)


name: H(+)(in) + L-aspartate(out) + phosphate(in) <=> H(+)(out) + L-aspartate(in) + phosphate(out)


name: (1S,2R,4S)-neodihydrocarveol + NAD(+) = (1S,4S)-dihydrocarvone + H(+) + NADH


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Xenopus tropicalis)


name: (9Z)-hexadecenoyl-CoA + AH2 + O2 <=> (9Z,12Z)-hexadecadienoyl-CoA + A + 2 H2O


name: CDK5 phosphorylates DARPP-32 on Thr75 (Xenopus tropicalis)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: ABCB9 transports peptides from cytosol to lysosomal lumen (Schizosaccharomyces pombe)


name: a 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine-DNA + H2O = a 3'-end 2'-deoxyribonucleotide 3'-phosphate-DNA + GMP + 2 H(+)


name: SYK autophosphorylates (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Saccharomyces cerevisiae)


name: Autoglucosylation of GYG1 complexed with GYS1-b (Dictyostelium discoideum)


name: (2E,6E)-farnesyl diphosphate = alpha-muurolene + diphosphate


name: D-erythrulose 4-phosphate => L-erythrulose 1-phosphate


name: Cleavage of uracil by TDG glycosylase (Rattus norvegicus)


name: chermesin D + S-adenosyl-L-methionine <=> chermesin D methyl ester + S-adenosyl-L-homocysteine


name: apulose + ATP <=> ADP + apulose 4-phosphate + H(+)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Danio rerio)


name: Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Rattus norvegicus)


name: GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol (Bos taurus)


name: H2O + menaquinone-8 + selenite => menaquinol-8 + selenate


name: SLC19A2/3 transport extracellular THMN to cytosol (Homo sapiens)


name: VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)


name: SRD5A2 binds SRD5A2 inhibitors (Canis familiaris)


name: DHFR2 reduces FOLA to DHF (Canis familiaris)


name: 2-deoxy-D-ribose 5-phosphate + thymine => dTMP + H2O


name: H(+) + NADH + sulfoacetyl-CoA => CoA + NAD(+) + sulfoacetaldehyde


name: MVB Vesicle Formation (Saccharomyces cerevisiae)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Xenopus tropicalis)


name: Hydrolysis of PC to PA by PLD (Caenorhabditis elegans)


name: H2O + oxaloacetate + propanoyl-CoA => 2-methylcitrate + CoA + H(+)


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Danio rerio)


name: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate => (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate + pyruvate


name: geranylgeranyl diphosphate = diphosphate + fusicocca-2,10(14)-diene


name: p-AMPK:AMP binds the ULK complex (Mus musculus)


name: [protein]-dithiol + O2 => [protein]-disulfide + H2O2


name: H2O + N(1)-acetylspermidine + O2 = 3-aminopropanal + H2O2 + N-acetylputrescine


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Sus scrofa)


name: 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate (Gallus gallus)


name: an N(6)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine => an adenosine in mRNA + S-adenosyl-L-methionine


name: ADRM1:26S proteaseome binds UCHL5 (Plasmodium falciparum)


name: dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] => CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate


name: 4,8-dimethylnonanoyl-CoA + H2O = 4,8-dimethylnonanoate + CoA + H(+)


name: H2O + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] = 3-deoxyglucosone + L-lysyl-[protein] + phosphate


name: Exocytosis of azurophil granule membrane proteins (Danio rerio)


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Saccharomyces cerevisiae)


name: 19-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase]


name: Elastic fibres bind associated proteins (Gallus gallus)


name: p75NTR interacts with RIP2 (Canis familiaris)


name: acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O (Mus musculus)


name: 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate


name: Association of procollagen type II (Mus musculus)


name: n H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) = n H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: Dimerization of procollagen type VI (Mus musculus)


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Xenopus tropicalis)


name: (2R,3S)-dihydrodehydrodiconiferyl alcohol + H(+) + NADPH = (S)-tetrahydrodehydrodiconiferyl alcohol + NADP(+)


name: 2-methylbutanamine + H2O + NAD(+) <=> 2-methylbutanal + H(+) + NADH + NH4(+)


name: SLC9B2 exchanges Na+ for H+ (Drosophila melanogaster)


name: bicarbonate:monoatomic anion antiporter activity


name: LINC01139 facilitates PTK6 autophosphorylation (Mus musculus)


name: Aquaporins passively transport water into cells (Homo sapiens)


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine


name: dodecanoyl-CoA + phytol <=> CoA + dodecanoate phytyl ester


name: 7-oxoheptanoyl-[ACP] + H2O + oxidized [flavodoxin] <=> 6-carboxyhexanoyl-[ACP] + reduced [flavodoxin]


name: crossover junction DNA endonuclease activity


name: Fall Back to Closed Pre-initiation Complex (Rattus norvegicus)


name: 5-guanidino-2-oxopentanoate + NH4(+) => H2O + iminoarginine


name: Defective CYP21A2 does not 21-hydroxylate PROG (Homo sapiens)


name: WIPIs bind PI3P (Drosophila melanogaster)


name: ERBB4s80:STAT5A complex translocates to the nucleus (Drosophila melanogaster)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Mus musculus)


name: (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O


name: METAP1/2 demethylates GNAT1 (Rattus norvegicus)


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S,25R)-24,26-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Defective TALDO1 does not transform SH7P, GA3P to Fru(6)P, E4P (Homo sapiens)


name: Conversion of PA into DAG by PAP-1 (Schizosaccharomyces pombe)


name: D-arabinitol 1-phosphate + NAD(+) <=> D-xylulose 5-phosphate + H(+) + NADH


name: asperlicin C + H(+) + NADPH + O2 = asperlicin E + H2O + NADP(+)


name: p-S363,S380,T573 RS6K translocates to the nucleus (Sus scrofa)


name: factor VIIIa + factor IXa -> factor VIIIa:factor IXa (Bos taurus)


name: TP53 binds the PRDM1 gene (Homo sapiens)


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP => an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose


name: Ni(2+) + sirohydrochlorin => 2 H(+) + Ni-sirohydrochlorin


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Homo sapiens)


name: SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Canis familiaris)


name: Activated MET binds RANBP9 and SOS1 (Mus musculus)


name: AKT1 phosphorylates NOTCH4 (Homo sapiens)


name: SOX9 and GATA4 bind the DMRT1 gene (Homo sapiens)


name: NAD+- protein-aspartate ADP-ribosyltransferase activity


name: MIOX oxidises Ins to GlcA (Drosophila melanogaster)


name: 4-hydroxyprotoasukamycin + H(+) + NADH + O2 => asukamycin + H2O + NAD(+)


name: chloride(out) + Na(+)(out) + serotonin(out) => chloride(in) + Na(+)(in) + serotonin(in)


name: (2E,6E)-farnesyl diphosphate + L-tryptophyl-[protein] <=> (2S,3R)-3-farnesyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate


name: Hv1 Mediated H+ Permeability (Bos taurus)


name: trichloro-p-hydroquinone reductive dehalogenase activity


name: RUNX1:CBFB binds the PRKCQ gene promoter (Homo sapiens)


name: TP receptor can bind thromboxane (Mus musculus)


name: (S)-piperazine-2-carboxamide + H2O <=> (S)-piperazine-2-carboxylate + NH4(+)


name: Caspase mediated cleavage of vimentin at IDVD (259) (Danio rerio)


name: DNA nucleases unhook the interstrand crosslink (ICL) (Sus scrofa)


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Rattus norvegicus)


name: 4-hydroxy-6-heptylpyran-2-one + 2 CO2 + 3 CoA => 2 H(+) + 2 malonyl-CoA + octanoyl-CoA


name: 3-amino-2-hydroxy-4-methoxybenzoate + H(+) + S-adenosyl-L-homocysteine => 3-amino-2,4-dihydroxybenzoate + S-adenosyl-L-methionine


name: PIAS4 SUMOylates HERC2 with SUMO1 (Sus scrofa)


name: (S)-3-amino-3-phenylpropanoate + pyruvate => 3-oxo-3-phenylpropanoate + L-alanine


name: MDM2 translocates to the cytosol (Sus scrofa)


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Canis familiaris)


name: trans-4-hydroxy-L-proline = (S)-1-pyrroline-5-carboxylate + H(+) + H2O


name: RDH5 oxidises 11cROL to 11cRAL (Canis familiaris)


name: AH2 + echinenone + O2 => 4'-hydroxyechinenone + A + H2O


name: H(+) + O-beta-D-glucosyl-cis-zeatin + UDP => cis-zeatin + UDP-alpha-D-glucose


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Caenorhabditis elegans)


name: GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Rattus norvegicus)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate <=> an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)


name: H2O + meso-2,6-diaminoheptanedioate + NADP(+) <=> (S)-2-amino-6-oxoheptanedioate + H(+) + NADPH + NH4(+)


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Sus scrofa)


name: KDM5A-D demethylate Me2K5-histone H3 (Canis familiaris)


name: METAP1/2 demethylates GNAT1 (Schizosaccharomyces pombe)


name: ADP + H(+) + pheophorbide a(out) + phosphate => ATP + H2O + pheophorbide a(in)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Homo sapiens)


name: ATP + L-serine => diphosphate + L-seryl-5'-AMP


name: dAMP(out) + NAD(+)(in) => dAMP(in) + NAD(+)(out)


name: RNF41 ubiquitinates activated ERBB3 (Bos taurus)


name: Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol (Homo sapiens)


name: N-acetylated spermidine (cytosol)=>N-acetylated spermidine (peroxisomal) (Homo sapiens)


name: BESTs transport cytosolic HCO3- to extracellular region (Drosophila melanogaster)


name: MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Mus musculus)


name: myricetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose => H(+) + myricetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP


name: a carboxylate(in) + nicotinate(out) => a carboxylate(out) + nicotinate(in)


name: Interleukin-1 receptor type 2 binds Interleukin 1 (Bos taurus)


name: Formation of meiotic holliday junction (Homo sapiens)


name: PSAP(195-273) dimer binds PE (Homo sapiens)


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Saccharomyces cerevisiae)


name: PKA phosphorylates DARPP-32 on Thr34 (Rattus norvegicus)


name: chlorophyllide a + NADP(+) => H(+) + NADPH + protochlorophyllide a


name: ADP + beta-citrylglutamate + H(+) + phosphate => ATP + citrate + L-glutamate


name: VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Homo sapiens)


name: ISGylation of E2 conjugating enzymes (Homo sapiens)


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Xenopus tropicalis)


name: EGFR autophosphorylation (Canis familiaris)


name: D-tryptophan + malonyl-CoA <=> CoA + H(+) + N(2)-malonyl-D-tryptophan


name: MPG glycosylase mediated recognition and binding of 3-methyladenine  (Homo sapiens)


name: 1-hexanoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+) => 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O


name: Activation of SHP2 through the binding to phospho-Gab1 (Homo sapiens)


name: Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Drosophila melanogaster)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Homo sapiens)


name: RHOD binds effectors at the mitochondrial outer membrane (Bos taurus)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Caenorhabditis elegans)


name: 2-oxoglutarate + L-leucine <=> 4-methyl-2-oxopentanoate + L-glutamate


name: hydrogen sulfide + O-succinyl-L-homoserine => L-homocysteine + succinate


name: TRIAP1 binds PRELID1, PRELID3A (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-ethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: FMNH2 + N-acetyl-S-methyl-L-cysteine + O2 = (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: H2O2 diffuses from the mitochondrial matrix to the cytosol (Homo sapiens)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Gallus gallus)


name: TFIIH binds GG-NER site to form a verification complex (Caenorhabditis elegans)


name: MSK1 activates CREB (Caenorhabditis elegans)


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + 2 succinate


name: 2-oxobutanoate + H(+) + NADPH => 2-hydroxybutanoate + NADP(+)


name: Homodimerization of VEGF proteins (Xenopus tropicalis)


name: p-6Y-SYK phosphorylates BLNK (SLP65) (Rattus norvegicus)


name: IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Homo sapiens)


name: ESR-associated SRC autophosphorylates (Sus scrofa)


name: Degradation of ubiquitinated SKI/SKIL (Danio rerio)


name: PLCG1 phosphorylation by p-EGFR:p-ERBB2 (Homo sapiens)


name: (2E)-decenoyl-[ACP] + H(+) + NADH = decanoyl-[ACP] + NAD(+)


name: H(+) + N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine => L-histidyl-[protein] + S-adenosyl-L-methionine


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Xenopus tropicalis)


name: Activated FGFR2 binds FRS2 (Canis familiaris)


name: FUOM isomerises alpha-Fuc to beta-Fuc (Rattus norvegicus)


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Rattus norvegicus)


name: an adenosine in tRNA + S-adenosyl-L-methionine <=> an N(1)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: STAB2:ligand is endocytosed (Homo sapiens)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Plasmodium falciparum)


name: 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose => 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: diphosphate + pestalodiol => dimethylallyl diphosphate + siccayne


name: H2O + homogentisate + NADP(+) => 4-hydroxyphenylacetate + H(+) + NADPH + O2


name: (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(12Z,15Z,18Z,21Z)-tetracosatetraenoyl-CoA + CO2 + CoA


name: nicotinamide + S-adenosyl-L-methionine = 1-methylnicotinamide + S-adenosyl-L-homocysteine


name: phosphatidylinositol phosphate 5-phosphatase activity


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4 (Xenopus tropicalis)


name: a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + 2 S-adenosyl-L-homocysteine => a 5'-end (5'-phospho)-ribonucleoside-RNA + 2 S-adenosyl-L-methionine


name: ESR1 binds ESR1 antagonists (Danio rerio)


name: PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Drosophila melanogaster)


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Xenopus tropicalis)


name: (Z)-(4-hydroxyphenyl)acetaldehyde oxime <=> 4-hydroxyphenylacetonitrile + H2O


name: p-4Y-PLCG1 dissociates from activated FGFR1 (Sus scrofa)


name: a globoside Gb4Cer + H2O <=> a globoside Gb3Cer + N-acetyl-beta-D-galactosamine


name: "Peptidylamino-acid hydrolases or acylamino-acid hydrolases"


name: H2O + N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine = 4-amino-5-aminomethyl-2-methylpyrimidine + formate


name: Homo- or heterodimerization of RAF downstream of mutant RAS (Homo sapiens)


name: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine


name: eNOS associates with Caveolin-1 (Sus scrofa)


name: EGFR non-clathrin mediated endocytosis (Homo sapiens)


name: Caspase-6 translocates to the nucleus (Xenopus tropicalis)


name: an alkanesulfonate + FMNH2 + O2 => an aldehyde + FMN + 2 H(+) + H2O + sulfite


name: BIL binds GSTA1, FABP1 (Xenopus tropicalis)


name: 3beta-hydroxyandrost-5-en-17-one + O2 + reduced [NADPH--hemoprotein reductase] = 3beta,16alpha-dihydroxy-androst-5-en-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase]


name: AVPR1A,B bind desmopressin (Mus musculus)


name: a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: KRAS4B recycles to the plasma membrane (Rattus norvegicus)


name: TFAP2C translocates to the nucleus (Xenopus tropicalis)


name: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-apiose <=> 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + H(+) + UDP


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Plasmodium falciparum)


name: CLN3 transports GalCer to plasma membrane (Caenorhabditis elegans)


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Bos taurus)


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Mus musculus)


name: H(+) + 2 malonyl-CoA + nicotinyl-CoA = 4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one + 2 CO2 + 3 CoA


name: ATP + H2O + L-glutamine + UTP => ADP + CTP + 2 H(+) + L-glutamate + phosphate


name: (E)-hexadec-2-enoate(out) + ATP(in) + CoA(in) + H(+)(out) => (2E)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: EDNRA, EDNRB bind non-selective ERAs (Bos taurus)


name: [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine


name: (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + tetradecanoyl-[ACP] => ((9Z)-hexadecenoyl-tetradecanoyl)-(Kdo)2-lipid A + holo-[ACP]


name: (2Z,6E)-farnesyl diphosphate + 11 isopentenyl diphosphate => di-trans,undeca-cis-tetradecaprenyl diphosphate + 11 diphosphate


name: USP19 binds HIF1A,BIRC2,BIRC3 (Canis familiaris)


name: D-dopa + H2O + O2 = 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: Truncated Alpha-1-Microglobulin binds heme (Homo sapiens)


name: Formation of active mTORC1 complex (Xenopus tropicalis)


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Gallus gallus)


name: Ubiquitination of phospho-p27/p21 (Caenorhabditis elegans)


name: GALNT3 transfers GalNAc to FGF23 (Bos taurus)


name: (8Z,11Z,14Z)-heptadecatrienal + CO2 + H2O => (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + H(+)


name: trans-2-coumarate + UDP-alpha-D-glucose => H(+) + trans-beta-D-glucosyl-2-hydroxycinnamate + UDP


name: type 5 metabotropic glutamate receptor binding


name: a 4,5-didehydrojasmonate + H(+) + NADPH <=> a jasmonate + NADP(+)


name: an N-acyl-(4R)-4-hydroxysphinganine + H(+) + mannosyldiinositol-1-phosphate => an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Mus musculus)


name: 2 CO2 + 2 H2O + protoporphyrinogen IX => coproporphyrinogen III + 2 H(+) + O2


name: H(+)(in) + uridine(in) <=> H(+)(out) + uridine(out)


name: (S)-lactate(in) + urate(out) => (S)-lactate(out) + urate(in)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Xenopus tropicalis)


name: ATP + H2O + L-proline(out) <=> ADP + H(+) + L-proline(in) + phosphate


name: RND2 binds GTP (Schizosaccharomyces pombe)


name: (2E,6E)-farnesyl diphosphate = (+)-thujopsene + diphosphate


name: SN-38 + UDP-alpha-D-glucuronate = H(+) + SN-38 O-beta-D-glucuronide + UDP


name: [pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate


name: "([Pyruvate, water dikinase] phosphate) phosphotransferase"


name: 1-O-hexadecyl-2-amino-sn-glycerol + ATP => 1-O-hexadecyl-2-desoxy-2-amino-sn-glycero-3-phosphate + ADP + H(+)


name: aldosterone hemiacetal 18-beta-glucuronide + H(+) + UDP => aldosterone hemiacetal + UDP-alpha-D-glucuronate


name: [small archaeal modifier protein]-C-terminal Gly-Gly + ATP + H(+) = [small archaeal modifier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: (1S,5S)-beta-pinene + diphosphate => (2E)-geranyl diphosphate


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Canis familiaris)


name: TRAF1 binds TRAF2 within TNFR1 signaling complex (Bos taurus)


name: (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + AH2 <=> (R)-2-hydroxy-(9Z,12Z,15Z)-octadecatrienoate + A + H2O


name: Activated protein C cleaves Factor Va intermediate form for Factor Va (Gallus gallus)


name: gibberellin A20 carboxyl methyltransferase activity


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Bos taurus)


name: 2 Fe(III)-[cytochrome c] + 2 thiosulfate = 2 Fe(II)-[cytochrome c] + 2 H(+) + tetrathionate


name: ATP + H2O + urea(out) => ADP + H(+) + phosphate + urea(in)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Danio rerio)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Sus scrofa)


name: Tachykinin receptor 1 (NK1) binds to substance P (Canis familiaris)


name: H(+) + O-phospho-L-serine + phosphate => diphosphate + L-serine


name: Association of HMGB1/HMGB2 with chromatin (Bos taurus)


name: (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA => (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine


name: ASC binds Caspase-8 complex (Canis familiaris)


name: ROCK1,ROCK2 are activated (Rattus norvegicus)


name: Change of PKC theta conformation (Homo sapiens)


name: Branching and elongation of mother and daughter filaments (Mus musculus)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Homo sapiens)


name: 4'-demethylrebeccamycin + H2O = beta-D-glucose + dichloroarcyriaflavin A


name: Oligomerization of BCL10 and MALT1 (Bos taurus)


name: RPA binds to the Flap on the C-strand (Bos taurus)


name: 2 Na(+)(out) + tauroursodeoxycholate(out) <=> 2 Na(+)(in) + tauroursodeoxycholate(in)


name: 4-coumaroyl-CoA + S-adenosyl-L-methionine <=> CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine


name: Docking of Mature Replication Dependent Histone mRNA with the NPC (Sus scrofa)


name: NRF1, PPRC1, NRF2 bind the TFAM promoter (Homo sapiens)


name: H2O + L,L-cystathionine => L-homocysteine + L-serine


name: 14-3-3 proteins bind AKT-phosphorylated FOXO4 (Homo sapiens)


name: "Endopeptidases of unknown catalytic mechanism"


name: GCL ligates L-Glu to L-Cys (Caenorhabditis elegans)


name: Caspase 3-mediated cleavage of DFF45 (117) (Drosophila melanogaster)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA


name: Dissociation of CI from COS (Drosophila melanogaster)


name: Formation of AT-AC C complex (Gallus gallus)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate => 3-hydroxypent-4-ene nitrile + sulfate + sulfur


name: DELE1(143-515) is released into the cytosol (Homo sapiens)


name: bis(beta-D-glucosyl) crocetin + UDP => beta-D-glucosyl crocetin + UDP-alpha-D-glucose


name: SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)


name: AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Bos taurus)


name: L1 interaction with Integrins (Mus musculus)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Mus musculus)


name: a ubiquinone + keto-D-fructose => 5-dehydro-D-fructose + a ubiquinol


name: p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)


name: 10-epi-juneol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: Fe(2+)(out) + 2 hydrogencarbonate(out) => Fe(2+)(in) + 2 hydrogencarbonate(in)


name: AKT phosphorylates MKRN1 (Drosophila melanogaster)


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Homo sapiens)


name: TBC1D20 binds RAB1:GTP (Drosophila melanogaster)


name: Interaction of MyoD:E protein with MEF2 (Drosophila melanogaster)


name: H2O + kynurenate + L-phenylalanine => 3-phenylpyruvate + L-kynurenine


name: a quinone + reduced coenzyme F420-(gamma-L-Glu)(n) => a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: ATP + CoA + dinor-OPDA => AMP + dinor-OPDA-CoA + diphosphate


name: 4-methyl-3-nitrocatechol + H(+) + NAD(+) + nitrite => 2,3-dinitrotoluene + NADH + O2


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Dictyostelium discoideum)


name: 2-oxoglutarate + L-phenylalanine <=> 3-phenylpyruvate + L-glutamate


name: D-erythrose 4-phosphate + L-lysyl-[protein] => H2O + N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein]


name: (R)-reticuline + S-adenosyl-L-methionine <=> (R)-tembetarine + H(+) + S-adenosyl-L-homocysteine


name: ANKLE2 binds VRK1,(VRK2) (Canis familiaris)


name: ESD dimer hydrolyses S-FGSH to GSH (Drosophila melanogaster)


name: H2O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Canis familiaris)


name: 3-methylundecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: NTRK2-phosphorylated FRS2 binds PTPN11 (Homo sapiens)


name: Accumulation of M1 at the inner leaflet of the lipid bilayer (Homo sapiens)


name: 5-oxo-L-proline(out) + 2 Na(+)(out) = 5-oxo-L-proline(in) + 2 Na(+)(in)


name: SRC-1 phosphorylates p-Y397-PTK2 (Bos taurus)


name: low-affinity nitrate transmembrane transporter activity


name: beta-D-fructose 6-phosphate => alpha-D-glucose 6-phosphate


name: ATP + H(+) + hexanoate + NADPH = AMP + diphosphate + hexanal + NADP(+)


name: (R)-2-hydroxyglutarate + pyruvate <=> (R)-lactate + 2-oxoglutarate


name: Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Homo sapiens)


name: Recruitment of Telomerase RNP to the Telomeric Chromosome End (Canis familiaris)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Homo sapiens)


name: p-4Y-PLCG1 dissociates from activated FGFR1 (Gallus gallus)


name: METAP1/2 demethylates GNAT1 (Danio rerio)


name: 2-oxoglutarate + dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose = dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + L-glutamate


name: 7-dehydrocholesterol + 2 H2O + NADP(+) => cholesterol + H(+) + NADPH + O2


name: Fusion of late-endosome derived vesicles at the TGN (Gallus gallus)


name: transforming growth factor beta receptor activity


name: 2-hydroxyoctanoyl-CoA + CO2 + succinate => 2-oxoglutarate + O2 + octanoyl-CoA


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Rattus norvegicus)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Homo sapiens)


name: lactose transmembrane transporter activity


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Canis familiaris)


name: CDK and DDK associate with the Mcm10:pre-replicative complex (Sus scrofa)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Rattus norvegicus)


name: (12R)-hydroxy-(9Z)-octadecenoyl-CoA + 1,2-di-(12R-hydroxy-9Z-octadecenoyl)-sn-glycerol <=> 1,2,3-tri-(12R-hydroxy-9Z-octadecenoyl)-glycerol + CoA


name: a myo-inositol phosphate + H2O = myo-inositol + phosphate


name: CR2 RAF1 mutants don't bind YWHAB (Homo sapiens)


name: RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Drosophila melanogaster)


name: Expression of PTGDS in testis differentiation (Homo sapiens)


name: (R)-lipoate(out) + 2 Na(+)(out) => (R)-lipoate(in) + 2 Na(+)(in)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Homo sapiens)


name: CES1trimer hydrolyses ACEI pro-drugs to ACEIs (Mus musculus)


name: ATP + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide => 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + diphosphate


name: ADGRG heterodimer translocates to plasma membrane (Danio rerio)


name: (E)-coniferaldehyde + CoA + NADP(+) <=> (E)-feruloyl-CoA + H(+) + NADPH


name: D-threitol + NAD(+) = D-erythrulose + H(+) + NADH


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Danio rerio)


name: Dab2 is recruited to the junctional plaques (Homo sapiens)


name: alpha-maltose 6'-phosphate + H2O = D-glucose + D-glucose 6-phosphate


name: AJUBA facilitates AURKA autophosphorylation (Rattus norvegicus)


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Bos taurus)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Canis familiaris)


name: 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate + H(+) => 3,4-dihydroxypyridine + O-acetyl-L-serine


name: H(+) + holo-[ACP] + tetradecanoate => H2O + tetradecanoyl-[ACP]


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Danio rerio)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Bos taurus)


name: myo-inositol + phosphate => 1D-myo-inositol 5-phosphate + H2O


name: Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Mus musculus)


name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex (Canis familiaris)


name: 11,12-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O


name: 4-imidazolone-5-propanoate = H2O + trans-urocanate


name: RNA(n) + UTP = diphosphate + RNA(n)-3'-uridine ribonucleotide


name: DCC interaction with Netrin-1 (Caenorhabditis elegans)


name: Coumarin is 7-hydroxylated by CYP2A13 (Rattus norvegicus)


name: Protesomal degradation of K48polyUb-TRAF3 (Sus scrofa)


name: CDP-D-glucose + diphosphate => alpha-D-glucose 1-phosphate + CTP + H(+)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Homo sapiens)


name: UVSSA:USP7 deubiquitinates ERCC6 (Schizosaccharomyces pombe)


name: (3S)-3-hydroxy-D-aspartate <=> glycine + glyoxylate


name: HSPG2 (perlecan) binds alpha-dystroglycan (Caenorhabditis elegans)


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Dictyostelium discoideum)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Bos taurus)


name: C30 botryococcene + 2 S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Drosophila melanogaster)


name: BTLA interacts with HVEM (Canis familiaris)


name: acetyl-CoA + 20 H(+) + 9 malonyl-CoA + 13 NADPH + S-adenosyl-L-methionine = 9 CO2 + 10 CoA + 7 H2O + 13 NADP(+) + S-adenosyl-L-homocysteine + soppiline A


name: Phosphorylated ERF translocates to the cytosol (Canis familiaris)


name: (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADPH + O2 = (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: Kinesin-1 is a heterotetramer (Canis familiaris)


name: FRAT proteins bind GSK3beta (Rattus norvegicus)


name: N(pros)-phospho-L-histidyl-[protein](out) + sucrose = L-histidyl-[protein] + sucrose 6(G)-phosphate(in)


name: Expression of Phosphatidylinositol transfer protein alpha isoform (Homo sapiens)


name: MDM2 homodimers auto-ubiquitinate (Danio rerio)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+) => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: F-actin capping protein is a heterodimer (Homo sapiens)


name: Raf dimer inhibitors bind RAF heterodimers (Plasmodium falciparum)


name: aclacinomycin T + H2O <=> 15-demethylaclacinomycin T + methanol


name: kaempferol 7-O-beta-D-glucoside + malonyl-CoA <=> CoA + kaempferol 7-O-(6-O-malonyl-beta-D-glucoside)


name: (9Z)-octadecenoyl-CoA + dopamine <=> CoA + H(+) + N-(9Z-octadecanoyl)-dopamine


name: Prolysyl oxidase activation (Bos taurus)


name: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H(+) + nitrite => 5-nitrosalicylate + O2


name: cimicifugate E + CoA => (2R,3S)-piscidate + (E)-feruloyl-CoA


name: alpha-D-mannosyl-(1->4)-[3-O-methyl-alpha-D-mannosyl-(1->4)](n)-1-O,3-O-dimethyl-alpha-D-mannose + GDP + H(+) => [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-1-O,3-O-dimethyl-alpha-D-mannose + GDP-alpha-D-mannose


name: USP30 binds ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Rattus norvegicus)


name: Interaction of ABL1 with CDO complex (Homo sapiens)


name: (S)-propane-1,2-diol + NAD(+) => (S)-lactaldehyde + H(+) + NADH


name: Phosphorylated OPTN translocates to the nucleus (Danio rerio)


name: 3,5-dimethyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + H(+) + S-adenosyl-L-homocysteine => 3-methyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + S-adenosyl-L-methionine


name: NOTCH1 stimulates HES5 transcription (Homo sapiens)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Mus musculus)


name: (2R,3R)-dihydrokaempferol + CO2 + succinate => (2S)-naringenin + 2-oxoglutarate + O2


name: E2F6:TFDP1:EPC1 binds the PRC2 complex (Gallus gallus)


name: H(+) + NADPH + O2 + phenylacetyl-CoA = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+)


name: 2-oxoglutarate + L-isoleucine + O2 <=> (4S)-4-hydroxy-L-isoleucine + CO2 + succinate


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Dictyostelium discoideum)


name: H(+)(in) + K(+)(out) + L-glutamate(in) + 3 Na(+)(in) => H(+)(out) + K(+)(in) + L-glutamate(out) + 3 Na(+)(out)


name: Phosphorylation of Cdc25C at Ser216 by CHEK2 (Caenorhabditis elegans)


name: TRiC/CCT binds unfolded G-protein beta subunit (Canis familiaris)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Schizosaccharomyces pombe)


name: a long-chain fatty acid + H(+) + hnu = a long-chain alkane + CO2


name: 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity


name: itaconyl-CoA + succinate => itaconate + succinyl-CoA


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Rattus norvegicus)


name: PAK1-3 dimer disassociates (Mus musculus)


name: 6-hydroxynicotinate + H2O + O2 = 2,6-dihydroxynicotinate + H2O2


name: Association of Ku heterodimer with viral DNA ends (Homo sapiens)


name: GDE1 hydrolyzes GroPIns (Canis familiaris)


name: L-glutamate + N-acetyl-L-glutamate 5-semialdehyde => 2-oxoglutarate + N(2)-acetyl-L-ornithine


name: Translocation of activated BAD protein to mitochondria (Canis familiaris)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Mus musculus)


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine <=> H(+) + kanamycin X + UDP


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Xenopus tropicalis)


name: RNF41 ubiquitinates activated ERBB3 (Homo sapiens)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + H2O <=> C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + L-glutamate


name: Nucleotide exchange on RAB1 (Rattus norvegicus)


name: SLC7A8-mediated uptake of neutral amino acids (Xenopus tropicalis)


name: (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H(+) + NADPH = (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+)


name: p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Homo sapiens)


name: Pannexin 1/Pannexin2 mediated neuronal gap junction communication (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O => a fatty acid + H(+) + sn-glycero-3-phospho-L-serine


name: ABC-type oligopeptide transporter activity


name: cis-cis-nepetalactol + NAD(+) = cis-cis-nepetalactone + H(+) + NADH


name: diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Sus scrofa)


name: PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Drosophila melanogaster)


name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Rattus norvegicus)


name: SPHK2 phosphorylates sphingoid (Bos taurus)


name: 7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) => 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Gallus gallus)


name: adenosine 3',5'-bisphosphate + H(+) + O-sulfo-L-tyrosine-[protein] => 3'-phosphoadenylyl sulfate + L-tyrosyl-[protein]


name: 2-glyceryl-prostaglandin H2 => 2-glyceryl-prostaglandin E2


name: SEPHS2 phosphorylates H2Se to form SELP (Drosophila melanogaster)


name: hexadecanoate + sphinganine <=> H2O + N-hexadecanoylsphinganine


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Danio rerio)


name: PIAS1,3 SUMOylate MBD1 with SUMO1 (Rattus norvegicus)


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O = a 5'-end 5'-monophospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H(+)


name: acetyl-CoA + cortisol = CoA + cortisol 21-acetate


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-choline <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: STON2 binds SYT proteins (Canis familiaris)


name: UGT8 transfers Gal from UDP-Gal to CERA (Bos taurus)


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene <=> H2O + rhodopin


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Gallus gallus)


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + CO2 + H2O2 => (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + H(+) + O2


name: H2O + sphing-4-enine-phosphocholine = H(+) + phosphocholine + sphing-4-enine


name: alpha-D-glucose + ATP => ADP + alpha-D-glucose 6-phosphate + H(+)


name: H(+) + NADPH + O2 + tert-butanol = 2-methylpropane-1,2-diol + H2O + NADP(+)


name: 7-chloro-L-tryptophan + AH2 + O2 <=> A + CO2 + 2 H2O + monodechloroaminopyrrolnitrin


name: a 2'-deoxycytidine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + O2


name: 1-propanol + NADP(+) = H(+) + NADPH + propanal


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Schizosaccharomyces pombe)


name: H2O + S-methyl-5'-thioadenosine <=> 5-(methylsulfanyl)-D-ribose + adenine


name: 2-hydroxyglutaryl-CoA + acetate => 2-hydroxyglutarate + acetyl-CoA


name: H(+) + H2O + hydroxyatrazine <=> ethylamine + N-isopropylammelide


name: 3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite


name: "assimilatory sulfite reductase (ferredoxin)"


name: SAICAR => AICAR + Fumarate (Mus musculus)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Canis familiaris)


name: 3-oxononanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxynonanoyl-[ACP] + NADP(+)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Caenorhabditis elegans)


name: PTPN11 is phosphorylated (Xenopus tropicalis)


name: AH2 + cyclohex-2-enone => A + cyclohexanone


name: 4-pyridoxate + H(+) => 4-pyridoxolactone + H2O


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Mus musculus)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Canis familiaris)


name: tigogenin + UDP-alpha-D-glucose => H(+) + tigogenin 3-O-beta-D-glucopyranoside + UDP


name: L-histidinol + phosphate => H2O + L-histidinol phosphate


name: MUS81:EME1,EME2 cleaves D-loop (Rattus norvegicus)


name: protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity


name: Formation of ORC(2-5) complex (Bos taurus)


name: ICMT methylates S-Farn RAS proteins (Homo sapiens)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Homo sapiens)


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe (Mus musculus)


name: UVSSA:USP7 deubiquitinates ERCC6 (Gallus gallus)


name: (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(12Z,15Z,18Z,21Z)-tetracosatetraenoyl-CoA + CO2 + CoA


name: TRIM21 ubiquitinates SQSTM1 (Caenorhabditis elegans)


name: (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate => (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2


name: ADP + phosphate + thioglycyl-[methyl-coenzyme M reductase] => ATP + glycyl-[methyl-coenzyme M reductase] + hydrogen sulfide


name: N-(2,3-dihydroxybenzoyl)-L-serine trimer => enterobactin + H2O


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA => (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: H2O + N,N'-diacetylchitobiose => acetate + beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine


name: TRAF6 binding leads to IRAK1:TRAF6 release (Mus musculus)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Danio rerio)


name: a nucleoside 2',3'-cyclic phosphate + H2O => a nucleoside 3'-phosphate + H(+)


name: [(1->2)-beta-D-glucosyl](n) + UDP-alpha-D-glucose => [(1->2)-beta-D-glucosyl](n+1) + H(+) + UDP


name: ATR phosphorylates RPA2 (Drosophila melanogaster)


name: alpha-D-galactosyl-(1->3)-1D-myo-inositol + H(+) + UDP => myo-inositol + UDP-alpha-D-galactose


name: (5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Dictyostelium discoideum)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Schizosaccharomyces pombe)


name: 3-oxooctanedioyl-CoA + CoA => acetyl-CoA + hexanedioyl-CoA


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Gallus gallus)


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Mus musculus)


name: 2-hydroxyethane-1-sulfonate + NADP(+) = H(+) + NADPH + sulfoacetaldehyde


name: 2 cob(II)alamin-[cyanocobalamin reductase] + 2 hydrogen cyanide + NADP(+) = 2 apo-[cyanocobalamin reductase] + 2 cyanocob(III)alamin + H(+) + NADPH


name: p-PKR dimer phosphorylates CDK1 (Xenopus tropicalis)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-threonyl-[protein] => acetyl-CoA + N-terminal L-methionyl-L-threonyl-[protein]


name: erythromycin D + H(+) + NADPH + O2 => erythromycin C + H2O + NADP(+)


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Mus musculus)


name: 5-taurinomethyluridine(34) in tRNA + AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] => 5-taurinomethyl-2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]


name: tRNA uridine(34) acetyltransferase activity


name: alpha,alpha-trehalose 6-phosphate + H(+) + TDP => D-glucose 6-phosphate + TDP-alpha-D-glucose


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: 11DCORST translocates from cytosol to mitochondrial matrix (Homo sapiens)


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Mus musculus)


name: Recruitment of Grb2 to pFAK:NCAM1 (Rattus norvegicus)


name: Complement factor I inactivates C3b (Gallus gallus)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: SOAT can transport taurolithocholate-3-sulphate (Drosophila melanogaster)


name: RHOT1 binds effectors at the mitochondrial outer membrane (Saccharomyces cerevisiae)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Caenorhabditis elegans)


name: 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + pisiferate => ferruginol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP => 1D-myo-inositol hexakisphosphate + ATP


name: an omega-hydroxy-ultra-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => an omega-methyl-ultra-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase]


name: Rv3364c binds cathepsin G (Homo sapiens)


name: histamine + S-adenosyl-L-methionine = H(+) + N(tau)-methylhistamine + S-adenosyl-L-homocysteine


name: anthranilate + ATP + CoA = AMP + anthraniloyl-CoA + diphosphate


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Homo sapiens)


name: docosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 2-hydroxydocosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: H(+)(in) + L-alanine(in) <=> H(+)(out) + L-alanine(out)


name: acetyl-CoA + dihydroxyacetone phosphate => 3-hydroxy-2,4-dioxopentyl phosphate + CoA


name: epitestosterone 17-sulfate(out) + 2 Na(+)(out) = epitestosterone 17-sulfate(in) + 2 Na(+)(in)


name: TOPORS SUMOylates IKBKE with SUMO1 (Bos taurus)


name: Receptors CCR3, 4 and 5 bind CCL5 ligand (Gallus gallus)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Danio rerio)


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)


name: acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)


name: RhCG mediates ammonium efflux out of kidney collecting duct cells (Drosophila melanogaster)


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Xenopus tropicalis)


name: DRD2 antagonist drugs bind to DRD2 (Sus scrofa)


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Saccharomyces cerevisiae)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + CoA + H(+) => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Rattus norvegicus)


name: DECR2 reduces LCtE-CoA to t3enoyl-CoA (Bos taurus)


name: Recruited STAT5 is phosphorylated (Bos taurus)


name: PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Sus scrofa)


name: 11-cis-retinoate + 2 H(+) + NADH => 11-cis-retinal + H2O + NAD(+)


name: ATM phosphorylates RBBP8 (Gallus gallus)


name: 3,17-dihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMNH2 + O2 => 3,4,17-trihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMN + H(+) + H2O


name: inositol diphosphate tetrakisphosphate kinase activity


name: ERBB4 ubiquitination by WWP1/ITCH (Danio rerio)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Xenopus tropicalis)


name: fibrin multimer -> fibrin multimer, crosslinked + NH4+ (Sus scrofa)


name: USP10 deubiquitinates SNX3, CFTR (Sus scrofa)


name: DHI and DHICA polymerize forming eumelanin (Canis familiaris)


name: Activation of linoleic acid to linoleoyl-CoA (Danio rerio)


name: benzoate + H(+) + H2O2 => benzaldehyde + H2O + O2


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Bos taurus)


name: O2 + reduced [NADPH--hemoprotein reductase] + typhasterol => 7-oxatyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Saccharomyces cerevisiae)


name: 2 H(+) + siroheme = Fe(2+) + sirohydrochlorin


name: ATP + cob(II)yrinate c monoamide + H2O + L-glutamine = ADP + cob(II)yrinate a,c diamide + H(+) + L-glutamate + phosphate


name: ferruginol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + sugiol


name: Aquaporins passively transport water out of cells (Schizosaccharomyces pombe)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Homo sapiens)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Caenorhabditis elegans)


name: 5-hydroxyisourate + H2O => 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)


name: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate


name: Activated PLC gamma dissociates from the PDGF receptor (Drosophila melanogaster)


name: FLIP(L) and procaspase-8 form heterodimer (Bos taurus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: Secretion of transmembrane collagens (Homo sapiens)


name: CALCR binds erenumab (Drosophila melanogaster)


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Mus musculus)


name: alpha-D-glucose + ATP = ADP + alpha-D-glucose 6-phosphate + H(+)


name: [(1->2)-beta-D-mannosyl](n+1) + GDP + H(+) => [(1->2)-beta-D-mannosyl](n) + GDP-alpha-D-mannose


name: 3-methyl-(2E)-glutaconyl-CoA + ADP + H(+) + phosphate => 3-methyl-(2E)-butenoyl-CoA + ATP + hydrogencarbonate


name: ATP + L-aspartate => 4-phospho-L-aspartate + ADP


name: STON2 binds SYT proteins (Caenorhabditis elegans)


name: H2O + L-2-aminopentanoate + O2 = 2-oxopentanoate + H2O2 + NH4(+)


name: ATP + N-acetyl-D-muramate => ADP + H(+) + N-acetyl-D-muramate 6-phosphate


name: n H(+)(out) + taurocholate(out) = n H(+)(in) + taurocholate(in)


name: DHF is reduced to tetrahydrofolate (THF) (Sus scrofa)


name: 2 Fe(II)-[cytochrome c] + 2 H(+) + L-dehydroascorbate => 2 Fe(III)-[cytochrome c] + L-ascorbate


name: glycerol + NADP(+) => H(+) + L-glyceraldehyde + NADPH


name: UDP-alpha-D-glucose + vancomycin aglycone <=> devancoaminyl-vancomycin + UDP


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)


name: 2 chloride(out) + hydrogencarbonate(in) <=> 2 chloride(in) + hydrogencarbonate(out)


name: PTGS1 dimer binds PTGS1 Inhibitors (Danio rerio)


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Canis familiaris)


name: ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Drosophila melanogaster)


name: N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: botE LC cleaves target cell SNAP25 (Homo sapiens)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Canis familiaris)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: "[methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]--tetrahydrofolate methyltransferase"


name: Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) (Bos taurus)


name: LEFTY binds the EGF-CFC coreceptor in the NODAL receptor (Homo sapiens)


name: NTRK2-phosphorylated FRS2 binds GRB2 (Homo sapiens)


name: an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of Cx43 by c-src (Sus scrofa)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen (Bos taurus)


name: PGD2 is dehydrated to 15d-PGD2 (Homo sapiens)


name: steviolmonoside + UDP-alpha-D-glucose = H(+) + steviolbioside + UDP


name: an organic molecule + O2 + reduced [NADPH--hemoprotein reductase] = an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 bilirubin-glucuronoside <=> bilirubin IXalpha + bilirubin-bisglucuronoside


name: Collagen types VI, IX bind integrin alpha10beta1 (Bos taurus)


name: baicalein + UDP-alpha-D-glucuronate = baicalin + UDP


name: 13-deoxycarminomycin + H(+) + NADPH + O2 = 13-dihydrocarminomycin + H2O + NADP(+)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Sus scrofa)


name: acetyl-CoA + L-lysine => CoA + H(+) + N(6)-acetyl-L-lysine


name: p-S158,221-HuR binds mRNA (Canis familiaris)


name: Intrinsic nucleotide exchange on RAS (Sus scrofa)


name: Auto-ubiquitination of TRAF6 (Canis familiaris)


name: LKB1 forms a trimeric complex with STRAD and MO25 (Canis familiaris)


name: (9Z,12Z)-octadecadienamide + H2O <=> (9Z,12Z)-octadecadienoate + NH4(+)


name: RAS:GTP binds RAL GDS proteins (Caenorhabditis elegans)


name: acetyl-CoA + L-2,4-diaminobutanoate => (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Sus scrofa)


name: 2-methyl-3-oxopropanoate + H(+) + NADH => 3-hydroxy-2-methylpropanoate + NAD(+)


name: prostaglandin J2-S-(R)-glutathione => glutathione + prostaglandin J2


name: 3-oxopropanoate + CoA + H2O + NAD(+) = acetyl-CoA + H(+) + hydrogencarbonate + NADH


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Sus scrofa)


name: PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Drosophila melanogaster)


name: Ubiquitination of phospho-p27/p21 (Sus scrofa)


name: Neurotensin receptors can bind neurotensins (Sus scrofa)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: H2O + neopikromycin + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: RAC2 binds effectors at the plasma membrane (Caenorhabditis elegans)


name: RHOD translocates to the mitochondrial outer membrane (Drosophila melanogaster)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Bos taurus)


name: Furin cleaves pro-BGLAP to BGLAP (Xenopus tropicalis)


name: Interleukin-1 receptor type 2 binds Interleukin 1 (Rattus norvegicus)


name: 6-carboxyhex-2-enoyl-CoA + H(+) + NADH => 6-carboxyhexanoyl-CoA + NAD(+)


name: 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol => 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O


name: RAB:GTP recruits GBF1 to the Golgi membrane (Caenorhabditis elegans)


name: H(+) + NADH + O2 + propane <=> H2O + NAD(+) + propan-2-ol


name: 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O <=> 2-glutaroyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Chloride ion and N-acyl group react to chloramide (Homo sapiens)


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Homo sapiens)


name: ST3GAL2,3 transfer Neu5Ac to gangliosides (Mus musculus)


name: 2 A + hydroxylamine + NH4(+) = 2 AH2 + H(+) + H2O + N2


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Canis familiaris)


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Xenopus tropicalis)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Homo sapiens)


name: GNRHR binds chemical antagonists (Gallus gallus)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Rattus norvegicus)


name: STAMBPL1 is a deubiquitinase (Rattus norvegicus)


name: 3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O2 => 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Rattus norvegicus)


name: IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)


name: 2-carboxyhexacosanoyl-CoA + ADP + H(+) + phosphate => ATP + hexacosanoyl-CoA + hydrogencarbonate


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)


name: Expression of PRDM1 in primordial germ cells (Homo sapiens)


name: GPVI stimulates PI3K beta, gamma (Canis familiaris)


name: ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (Canis familiaris)


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Canis familiaris)


name: carvacrol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => alpha-terpinene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: cyclic tetraadenylate <=> 2 5'-hydroxy-diadenylate 2',3'-cylic phosphate


name: NOTCH3-ligand complex is cleaved to produce NEXT3 (Rattus norvegicus)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Mus musculus)


name: LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Canis familiaris)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Rattus norvegicus)


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Rattus norvegicus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose


name: Caspase mediated cleavage of alpha-II-Fodrin (Gallus gallus)


name: DIBOA + UDP-alpha-D-glucose = DIBOA beta-D-glucoside + H(+) + UDP


name: ADP + CO2 + phosphoenolpyruvate => ATP + oxaloacetate


name: 2'-deoxyuridine + NH4(+) => 2'-deoxycytidine + H(+) + H2O


name: ATP hydrolysis by HSP70 (Xenopus tropicalis)


name: 2-oxoglutarate + O2 + verruculide A => chrodrimanin T + CO2 + succinate


name: ALDH4A1 oxidises L-GluSS to Glu (Mus musculus)


name: Factor H binds to C3b (Canis familiaris)


name: pseudouridine(32) in tRNA => uridine(32) in tRNA


name: (9Z)-octadecenoate + O2 <=> (2R,9Z)-2-hydroperoxyoctadecenoate


name: Binding of ERp57 (Saccharomyces cerevisiae)


name: a 3'-hydroxyflavone + S-adenosyl-L-methionine => a 3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: SERPINC1 binds SERPINC1 activators (Rattus norvegicus)


name: (2E)-geranyl diphosphate + H2O <=> (R)-alpha-terpineol + diphosphate


name: GDP-beta-L-fucose + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate = GDP + H(+) + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose <=> 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Saccharomyces cerevisiae)


name: 3-demethylubiquinol-8 + A + H2O => 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + AH2 + O2


name: ERBB4s80 forms a complex with estrogen receptor ESR1 (Homo sapiens)


name: 3',4,7-trihydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => 3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine


name: FLT3 ITD- and STAT5-dependent CDKN1A gene expression (Homo sapiens)


name: Thyrotropin is a heterodimer (Bos taurus)


name: [(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O <=> [(1->4)-3,6-bisphospho-alpha-D-glucosyl](n) + n AMP + 2n H(+) + n phosphate


name: COPI vesicle uncoating at the ER (Homo sapiens)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Canis familiaris)


name: 2-oxoglutarate(out) + succinate(in) = 2-oxoglutarate(in) + succinate(out)


name: p-AMPK:AMP binds the ULK complex (Gallus gallus)


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + S-adenosyl-L-methionine => griseophenone D + H(+) + S-adenosyl-L-homocysteine


name: butylamine + H2O + NAD(+) => butanal + H(+) + NADH + NH4(+)


name: 2-acyl LPS is acylated to PS by LPSAT (Canis familiaris)


name: Formation of DSIF complex  (Rattus norvegicus)


name: LONP1 binds mitochondrial inner membrane proteins (Drosophila melanogaster)


name: Gq activation by TP receptor (Caenorhabditis elegans)


name: SPHK1 phosphorylates sphingoid (Caenorhabditis elegans)


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Dictyostelium discoideum)


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Gallus gallus)


name: NUMB:ITCH binds GLI1 (Rattus norvegicus)


name: ERK5 translocates to the nucleus (Sus scrofa)


name: adenosine 3',5'-bisphosphate + H(+) + holo-[peptidyl-carrier protein] => apo-[peptidyl-carrier protein] + CoA


name: a 4alpha-methyl-3-oxosteroid + CO2 + NADH => a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD(+)


name: Activated MET binds GAB1 and GRB2 (Homo sapiens)


name: AH2 + ATP + 2 Co(II)-[methylamine-specific corrinoid protein] + H2O <=> A + ADP + 2 Co(I)-[methylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Plasmodium falciparum)


name: a Delta(14) steroid + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] => a 14alpha-methyl steroid + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin]


name: AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Drosophila melanogaster)


name: 2 H(+)(out) + nitrite(out) + 3 ubiquinol-8(in) = 2 H2O(out) + NH4(+)(out) + 3 ubiquinone-8(in)


name: DHFR dimer reduces FOLA to DHF (Dictyostelium discoideum)


name: Phosphorylation of E proteins by p38 MAPK (Homo sapiens)


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Caenorhabditis elegans)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Homo sapiens)


name: 3-acetylamino-4-hydroxybenzaldehyde + CoA + H(+) => 3-amino-4-hydroxybenzaldehyde + acetyl-CoA


name: L-aspartate(in) + L-tryptophan(out) <=> L-aspartate(out) + L-tryptophan(in)


name: adenosine 3',5'-bisphosphate + 2 H(+) + malonyl-4'-phosphopantetheine => H2O + malonyl-CoA


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Canis familiaris)


name: Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Mus musculus)


name: p-PKR dimer phosphorylates SNCA (Sus scrofa)


name: GLYAT-like proteins transfer glycine to ST-CoA to form SUA (Homo sapiens)


name: (E)-phenylacetaldehyde oxime = (Z)-phenylacetaldehyde oxime


name: 2-oxoglutarate + gibberellin A20 + O2 <=> CO2 + gibberellin A1 + succinate


name: Endosomal TLRs pass through the Golgi (Xenopus tropicalis)


name: ST8SIA5 transfers Neu5Ac to gangliosides (Xenopus tropicalis)


name: Phosphorylation of DCC by Fyn (Drosophila melanogaster)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Dictyostelium discoideum)


name: 2,5-dichlorohydroquinone reductive dehalogenase activity


name: Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol (Danio rerio)


name: NT5E:Zn2+ hydrolyses NAD+ (Homo sapiens)


name: MPI isomerises Fru6P to Man6P (Saccharomyces cerevisiae)


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Bos taurus)


name: (4R)-hydroxysphing-(8E)-enine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphing-(8E)-enine


name: ATP + H2O + itraconazole(in) <=> ADP + H(+) + itraconazole(out) + phosphate


name: Dimerization of Tie2/Ang1 complex (Homo sapiens)


name: Factor Xa inhibitors binds Xa (Gallus gallus)


name: putrescine transmembrane transporter activity


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Sus scrofa)


name: APAF1 binds AVEN (Drosophila melanogaster)


name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes (Homo sapiens)


name: Active FLT3 binds to SH2B3 (Homo sapiens)


name: Cargo-carrying vesicles bud from the TGN (Xenopus tropicalis)


name: (S)-4-hydroxy-2-oxopentanoate <=> (2Z)-2-hydroxypenta-2,4-dienoate + H2O


name: CO2 + fraxetin + succinate => 2-oxoglutarate + O2 + scopoletin


name: LGI3 binds ADAM22,23,synatxin1 (Sus scrofa)


name: an aldose + H(+) + NADPH => an alditol + NADP(+)


name: (2R,4S)-ketoconazole(in) + ATP + H2O => (2R,4S)-ketoconazole(out) + ADP + H(+) + phosphate


name: Recruitment of transition zone proteins (Sus scrofa)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Canis familiaris)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: (1R)-(2-amino-1-hydroxyethyl)phosphonate + O2 <=> glycine + 2 H(+) + phosphate


name: Linkage of L1 with treadmilling F-actin (Caenorhabditis elegans)


name: The 60S subunit joins the translation initiation complex  (Bos taurus)


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Xenopus tropicalis)


name: (6Z)-octadecenamide + H2O => (6Z)-octadecenoate + NH4(+)


name: ATP + deamido-NAD(+) = ADP + H(+) + nicotinate-adenine dinucleotide 3'-phosphate


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Saccharomyces cerevisiae)


name: AGO2 binds maternal endosiRNA (Homo sapiens)


name: PDPK1 phosphorylates PKN1,2,3 (Mus musculus)


name: alpha-D-ribose 1,5-bisphosphate + H(+) => alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + octadecanoate


name: beta-myrcene + O2 + reduced [NADPH--hemoprotein reductase] => (4R)-ipsdienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Mus musculus)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Homo sapiens)


name: Activated PLC gamma dissociates from the PDGF receptor (Mus musculus)


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H(+) + NADH = 4-pyridoxate + NAD(+)


name: CD151 interacts with BP180 and the integrin alpha 6 subunit (Canis familiaris)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Sus scrofa)


name: (E)-phenylacetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] <=> (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Drosophila melanogaster)


name: diphosphate + phosphate + S-adenosyl-L-methionine => ATP + H2O + L-methionine


name: bergapten + S-adenosyl-L-homocysteine => bergaptol + S-adenosyl-L-methionine


name: WICH phosphorylates H2AFX on Y142 (Mus musculus)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Canis familiaris)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Mus musculus)


name: (1R,2R,3R)-prephytoene diphosphate = 15-cis-phytoene + diphosphate


name: Interaction of particulate antigens with dendritic cell receptors (Drosophila melanogaster)


name: Receptors CXCR4 and 7 bind CXCL12 ligand (Gallus gallus)


name: NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH + S-formylglutathione


name: chloride + FADH2 + ilicicolin B + O2 => FAD + H(+) + 2 H2O + ilicicolin A


name: phosphate(in) + succinate(out) = phosphate(out) + succinate(in)


name: alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ (Rattus norvegicus)


name: D-glyceraldehyde 3-phosphate + dihydroxyacetone => beta-D-fructose 6-phosphate


name: cis-aconitate + H(+) <=> CO2 + itaconate


name: SLC36A1-mediated uptake of glycine, proline, and alanine (Mus musculus)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a cardiolipin + ethanolamine


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H(+)


name: CD38 hydrolyses NAD+ to NAM and ADP-ribose (Mus musculus)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Mus musculus)


name: PGRMC2 binds Hemes (Dictyostelium discoideum)


name: p-AMPK:AMP binds the ULK complex (Canis familiaris)


name: Lactoperoxidase (LPO) produces OSCN- (Bos taurus)


name: baicalin + H2O => baicalein + D-glucuronate + H(+)


name: 2-phenylacetate + CoA + H(+) => H2O + phenylacetyl-CoA


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Mus musculus)


name: 3-oxododecanedioyl-CoA + CoA = acetyl-CoA + decanedioyl-CoA


name: 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine <=> 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine


name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Bos taurus)


name: 2-acyl LPC is acylated to PC by LPCAT (Danio rerio)


name: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O <=> 2-formylglutarate + NH4(+)


name: Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol (Homo sapiens)


name: methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity


name: cytidine(61) in tRNA(Asp) + S-adenosyl-L-methionine => 5-methylcytidine(61) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: Interaction of SHP1 and KIT (Canis familiaris)


name: 2 a menaquinol + n H(+)(in) + O2 = 2 a menaquinone + n H(+)(out) + 2 H2O(in)


name: ATP + H(+) + hexadecanoate => diphosphate + hexadecanoyl-AMP


name: dihydromethanophenazine => H2 + methanophenazine


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Sus scrofa)


name: CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) <=> alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: A + dihydrourocanate <=> AH2 + urocanate


name: voltage-gated potassium channel activity involved in SA node cell action potential depolarization


name: 2 AH2 + 2 formaldehyde + L-lysyl(4)-[histone H3] => 2 A + 2 H2O + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3]


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Sus scrofa)


name: Gbeta:gamma activation of PLC beta (Gallus gallus)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NAD(+) <=> 12alpha-hydroxy-3-oxochola-4-en-24-oate + H(+) + NADH


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Canis familiaris)


name: Dephosphorylation of p107 (RBL1) by PP2A (Rattus norvegicus)


name: 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine <=> (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]


name: eIF5B:GTP is hydrolyzed and released (Caenorhabditis elegans)


name: ABC-type 3',5'-cyclic GMP transmembrane transporter activity


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Danio rerio)


name: ESR1 binds ESR1 antagonists (Gallus gallus)


name: a 1-acyl-sn-glycero-2,3-cyclic phosphate + ethanolamine => a 1-acyl-sn-glycero-3-phosphoethanolamine


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Danio rerio)


name: a 2'-deoxyribonucleoside 5'-diphosphate + dGDP => a 2'-deoxyribonucleoside 5'-phosphate + dGTP


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Drosophila melanogaster)


name: Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol (Homo sapiens)


name: Netrin-1 induced DCC clustering (Drosophila melanogaster)


name: oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: 2-oxoglutarate + D-4-hydroxyphenylglycine <=> 4-hydroxyphenylglyoxylate + L-glutamate


name: ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine


name: OCT3 mediates renal uptake of organic cations (Gallus gallus)


name: ATM phosphorylates WHSC1 (Schizosaccharomyces pombe)


name: H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + secologanin => loganin + O2 + reduced [NADPH--hemoprotein reductase]


name: ATF2 acetylates histone H2B, H4 (Mus musculus)


name: (9S,10R)-epoxy-octadecanoate + H2O <=> 9R,10R-dihydroxyoctadecanoate


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Canis familiaris)


name: Caspase-mediated cleavage of Lamin B1 (Danio rerio)


name: TP53I3 oxidoreductase generates unstable semiquinones (Sus scrofa)


name: N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA <=> CoA + H(+) + N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein]


name: SUMOylation of RXRA with SUMO1 (Rattus norvegicus)


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)


name: CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 (Caenorhabditis elegans)


name: 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: (2R,3S,4S)-3,4-leucopelargonidin + 2-oxoglutarate + O2 = (4S)-2,3-dehydroleucopelargonidin + CO2 + H(+) + H2O + succinate


name: CDC6 association with ORC(1-6) at replication origins (Gallus gallus)


name: 9beta-pimara-7,15-diene + diphosphate => 9alpha-copalyl diphosphate


name: REV1 inserts dCMP opposite to AP sites in DNA (Bos taurus)


name: dihydroxyacetone phosphate <=> methylglyoxal + phosphate


name: Basigin binds MCT1, MCT3 and MCT4 (Gallus gallus)


name: Syndecans 1, 2, 4, (3) bind FGF2 (Rattus norvegicus)


name: caffeine + H(+) + NADPH + O2 = formaldehyde + H2O + NADP(+) + theobromine


name: HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Gallus gallus)


name: 2-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one + dimethylallyl diphosphate <=> 4-prenylphlormethylbutanophenone + diphosphate


name: a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)


name: 3-oxo-(5Z)-dodecenoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxy-(5Z)-dodecenoyl-[ACP] + NADP(+)


name: GSDMD (1-275) binds bacterial cardiolipin (Gallus gallus)


name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Mus musculus)


name: LYZ binds bacterial peptidoglycan (Bos taurus)


name: Recruitment of POLB to the AP site (Mus musculus)


name: 3-methyl-2-oxobutanoate + CO2 + NADH => (R)-3,3-dimethylmalate + NAD(+)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Sus scrofa)


name: ENPEP hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) (Canis familiaris)


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Bos taurus)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: GDP(out) + UTP(in) => GDP(in) + UTP(out)


name: hexadecanoyl-CoA + sphinga-(4E,8Z)-dienine <=> CoA + H(+) + N-hexadecanoylsphinga-(4E,8Z)-dienine


name: 2 CO2 + 2 formaldehyde + L-lysyl(9)-[histone H3] + 2 succinate => 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 O2


name: SLC5A2 binds gliflozins (Canis familiaris)


name: 1,2-dihexanoyl-3-(9Z-octadecenoyl)-sn-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1,2-dihexanoyl-sn-glycerol


name: FLT3 ITD- and NOX4-dependent H2O2 production (Homo sapiens)


name: 2 putrescine = NH4(+) + sym-homospermidine


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Xenopus tropicalis)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 => (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO2 + H2O + succinate


name: HSF1 acetylation at Lys80 (Homo sapiens)


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Dictyostelium discoideum)


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Caenorhabditis elegans)


name: Release of acetylcholine at the synapse (Canis familiaris)


name: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Drosophila melanogaster)


name: ATP + dodecanoate + H(+) => diphosphate + dodecanoyl-AMP


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Bos taurus)


name: uroporphyrinogen I => coproporphyrinogen I + 4 CO2 (Gallus gallus)


name: Formation of the MCC complex (Mus musculus)


name: ProGIP translocates from the ER Lumen to secretory granules (Mus musculus)


name: chondroitin 4'-sulfate => dermatan 4'-sulfate


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Drosophila melanogaster)


name: H(+) + NADPH + vellosimine => 10-deoxysarpagine + NADP(+)


name: 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine + H2O <=> 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + choline + H(+)


name: Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Saccharomyces cerevisiae)


name: Phosphorylation and release of IRF7 (Homo sapiens)


name: H2O + UDP-alpha-D-glucose => alpha-D-glucose 1-phosphate + 2 H(+) + UMP


name: guanine + NAD(+) <=> H(+) + N(2)-(ADP-D-ribosyl)-guanine + nicotinamide


name: promoter-enhancer loop anchoring activity


name: The Kiss receptor GPR54 binds kisspeptin (Homo sapiens)


name: Phosphorylation of COP1 at Ser-387  by ATM (Canis familiaris)


name: ADP + H(+) + phosphate + vincristine(out) => ATP + H2O + vincristine(in)


name: acetyl-CoA + 9 H(+) + 4 malonyl-CoA + 5 NADPH = 7-methylmellein + 3 CO2 + 5 CoA + 4 H2O + 5 NADP(+)


name: acetyl-CoA + spermine <=> CoA + H(+) + N(1)-acetylspermine


name: gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Rattus norvegicus)


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Rattus norvegicus)


name: H(+) + hexanal + NADPH => hexan-1-ol + NADP(+)


name: CYP46A1 24-hydroxylates CHOL (Rattus norvegicus)


name: Palmostatin B binds RAS depalmitoylases (Drosophila melanogaster)


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Caenorhabditis elegans)


name: JAK2 phosphorylation of GHR (Mus musculus)


name: 4-(trifluoromethyl)benzyl alcohol + NAD(+) = 4-(trifluoromethyl)benzaldehyde + H(+) + NADH


name: a 3-acyl-sn-glycerol + an acyl-CoA => a 1,3-diacyl-sn-glycerol + CoA


name: H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate = GMP + GTP + 2 H(+)


name: PAK1-3 phosphorylates VE-cadherin (Mus musculus)


name: 9-cis-retinol + NADP(+) = 9-cis-retinal + H(+) + NADPH


name: a 5'-end triphospho-guanosine in mRNA + H2O => a 5'-end diphospho-guanosine in mRNA + H(+) + phosphate


name: 7-isopropyl-4-methyloxepan-2-one + H2O = 6-hydroxy-3,7-dimethyloctanoate + H(+)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Homo sapiens)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Canis familiaris)


name: Removal of remaining Flap (Canis familiaris)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Gallus gallus)


name: GTP <=> cyclic pyranopterin phosphate + diphosphate


name: 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Rattus norvegicus)


name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Mus musculus)


name: L-alanine + L-threonine => H2O + L-alanyl-L-threonine


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Canis familiaris)


name: ARFGAPs stimulate ARF GTPase activity (Drosophila melanogaster)


name: a (2R,3R)-dihydroflavonol + CO2 + succinate => 2-oxoglutarate + a (2S)-flavan-4-one + O2


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Rattus norvegicus)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Drosophila melanogaster)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Rattus norvegicus)


name: Cleavage of hypoxanthine by MPG glycosylase (Danio rerio)


name: C5a anaphylatoxin chemotactic receptor binding


name: COX10 transforms heme to heme O (Drosophila melanogaster)


name: abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Homo sapiens)


name: Transphosphorylation of JAK1 (Rattus norvegicus)


name: H(+)(out) + L-isoleucine(in) <=> H(+)(in) + L-isoleucine(out)


name: L-alanine + L-glutamate => H2O + L-alanyl-L-glutamate


name: SUMOylation of DDX5 with SUMO1 (Dictyostelium discoideum)


name: 1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexanoate


name: aldehydo-D-glucose + L-lysyl-[protein] <=> H2O + N(6)-(D-fructosyl)-L-lysyl-[protein]


name: 1-(5-phosphoribosyl)imidazole-4-acetate + ADP + diphosphate + H(+) + phosphate => 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazole-4-acetate


name: RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)


name: adenosylcob(III)alamin 5'-phosphate + GMP + H(+) => adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate


name: ATP + CoA + propanoate <=> ADP + phosphate + propanoyl-CoA


name: Activated TLR4:TICAM1 recruits TRAF6 (Mus musculus)


name: 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine <=> 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Dictyostelium discoideum)


name: acetate + ATP <=> acetyl phosphate + ADP


name: alpha-D-glucose 1-phosphate + riboflavin => D-glucose + FMN


name: an all-trans-retinyl ester + H2O <=> 11-cis-retinol + a fatty acid + H(+)


name: (2E,6E)-farnesyl diphosphate => diphosphate + sesquithujene


name: 2 AH2 + all-trans-beta-carotene + 2 O2 => 2 A + echinenone + 3 H2O


name: 3-hydroxyhexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 3,16-dihydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated type I receptor phosphorylates SMAD2/3 directly (Drosophila melanogaster)


name: NEK6 and NEK7 phosphorylate EML4 (Sus scrofa)


name: CES1 hydrolyses sacubitril to sacubitrilat (Mus musculus)


name: aurachin C + H(+) + NADH + O2 <=> aurachin C epoxide + H2O + NAD(+)


name: 17beta-estradiol + UDP-alpha-D-glucuronate = 17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Plasmodium falciparum)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + NADP(+) => (2E,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H(+) + NADPH


name: ERCC1:XPF cleaves flaps generated by SSA (Rattus norvegicus)


name: GEFs activate RhoA,B,C (Schizosaccharomyces pombe)


name: (2S)-heptan-2-amine + H2O + NAD(+) = H(+) + heptan-2-one + NADH + NH4(+)


name: Adenylate cyclase converts ATP into cyclic AMP (Bos taurus)


name: ZnT5 transports zinc into the golgi apparatus (Danio rerio)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Drosophila melanogaster)


name: D-glucose(in) + H(+)(out) => D-glucose(out) + H(+)(in)


name: NKG2D homodimer interacting with ligands (Mus musculus)


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Mus musculus)


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Schizosaccharomyces pombe)


name: 19-hydroxyprostaglandin H1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + prostaglandin H1 + reduced [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate => allo-aromadendrene + diphosphate


name: NRXNs binds CASK tripartite complex (Homo sapiens)


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Canis familiaris)


name: adenosine(4220) in 28S rRNA + S-adenosyl-L-methionine => H(+) + N(6)-methyladenosine(4220) in 28S rRNA + S-adenosyl-L-homocysteine


name: (2R)-O-phospho-3-sulfolactate + H2O <=> (2R)-3-sulfolactate + phosphate


name: Release Of ADP From Myosin (Mus musculus)


name: GLI translocates to the nucleus (Drosophila melanogaster)


name: 2-phenylacetate + O2 + reduced [NADPH--hemoprotein reductase] = (2-hydroxyphenyl)acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3'-phosphoadenylyl sulfate(in) + adenosine 3',5'-bisphosphate(out) = 3'-phosphoadenylyl sulfate(out) + adenosine 3',5'-bisphosphate(in)


name: B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain (Drosophila melanogaster)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Mus musculus)


name: S100A8:S100A9 binds TLR4:LY96 (Gallus gallus)


name: H2O + N-acetyl-D-galactosamino-1,5-lactone <=> H(+) + N-acetyl-D-galactosaminate


name: SUMOylation of Histone H4 with SUMO1 (Mus musculus)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate => a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate


name: NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Bos taurus)


name: acetyl-CoA + butan-1-ol = butyl acetate + CoA


name: CYP2C19 5-hydroxylates omeprazole (Homo sapiens)


name: chloride(in) + Cs(+)(out) + 2 hydrogencarbonate(out) => chloride(out) + Cs(+)(in) + 2 hydrogencarbonate(in)


name: PKCdelta phosphorylates HuR (Drosophila melanogaster)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Rattus norvegicus)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Bos taurus)


name: 3-amino-5-hydroxybenzoate + ATP + holo-[aryl-carrier protein] => 3-amino-5-hydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate


name: RAC1 and CDC42 activate PAK2 (Sus scrofa)


name: ATP + H2O + L-cysteine(in) => ADP + H(+) + L-cysteine(out) + phosphate


name: (24S)-hydroxycholesterol + 3'-phosphoadenylyl sulfate => (24S)-hydroxycholesterol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: XDH oxidizes xanthine to form urate (Bos taurus)


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Mus musculus)


name: DNA nucleases unhook the interstrand crosslink (ICL) (Rattus norvegicus)


name: Integrin alpha5beta1 binds FN1 dimer (Homo sapiens)


name: L-erythrulose 1-phosphate = dihydroxyacetone phosphate + formaldehyde


name: NUAK1 phosphorylates TP53 (Rattus norvegicus)


name: sorbitol transmembrane transporter activity


name: CYP7B1 7-hydroxylates 25OH-CHOL (Mus musculus)


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Mus musculus)


name: HCFC1 binds SET1A complex (Caenorhabditis elegans)


name: 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + tetradecanoyl-CoA


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Caenorhabditis elegans)


name: cellobiose dehydrogenase (acceptor) activity


name: PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Rattus norvegicus)


name: glycyl-L-leucine(out) + 2 H(+)(out) <=> glycyl-L-leucine + 2 H(+)(in)


name: (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Mus musculus)


name: Activation of TAK1 complex bound to pUb-TRAF6 (Mus musculus)


name: CoA + H(+) + N-benzoylglycine => benzoyl-CoA + glycine


name: SCARB1:ligand is endocytosed (Homo sapiens)


name: CoA + H(+) + N(6)-tetradecanoyl-L-lysyl-[protein] => L-lysyl-[protein] + tetradecanoyl-CoA


name: (7R,8S)-7,8-diammoniononanoate + CO2 => (7R,8S)-8-amino-7-(carboxyamino)nonanoate + 2 H(+)


name: N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Xenopus tropicalis)


name: AKT phosphorylates FOXO transcription factors (Rattus norvegicus)


name: Succinate <=> Fumarate (with FAD redox reaction on enzyme) (Canis familiaris)


name: FMNH2 + NADH + O2 + uracil => (Z)-3-ureidoacrylate + FMN + H(+) + H2O + NAD(+)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Mus musculus)


name: Expression of MYOCD in cardiogenesis (Homo sapiens)


name: SLC16A10-mediated uptake of aromatic amino acids (Plasmodium falciparum)


name: Cleavage of NODAL proprotein (Homo sapiens)


name: PARG dePARylates PARP1,PARP2 (Dictyostelium discoideum)


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Mus musculus)


name: 2-hydroxy-2-methylpropanenitrile = acetone + hydrogen cyanide


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: NEDD4L ubiquitin ligase binds SMAD7 (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Drosophila melanogaster)


name: Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 (Rattus norvegicus)


name: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H(+) + O2 = aureusidin 6-O-beta-glucoside + H2O


name: 2 Na(+)(out) + nitrate(out) => 2 Na(+)(in) + nitrate(in)


name: oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor


name: Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Sus scrofa)


name: integrin binding involved in cell-matrix adhesion


name: a 2'-hydroxyisoflavone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => a 2'-unsubstituted isoflavone + O2 + reduced [NADPH--hemoprotein reductase]


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Rattus norvegicus)


name: CEBPA binds MYC gene:E2F1 (Homo sapiens)


name: RUNX1 binds PRC1 complexes (Homo sapiens)


name: ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)


name: 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Homo sapiens)


name: cytidine(48) in tRNA(Asp) + S-adenosyl-L-methionine => 5-methylcytidine(48) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: 2-methoxy-6-all-trans-heptaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine <=> 6-methoxy-3-methyl-2-all-trans-heptaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Bos taurus)


name: GGPS1 hexamer transfers IPPP to GPP (Saccharomyces cerevisiae)


name: a guanosine in RNA + glyoxal => an N(2)-(1-hydroxy-2-oxoethyl)-guanosine in RNA