name: 9-cis-beta-carotene 9',10'-cleavage oxygenase activity


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 16(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TFAP2A binds TFAP2B (Caenorhabditis elegans)


name: alpha-ketoglutarate transmembrane transporter activity


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Homo sapiens)


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Xenopus tropicalis)


name: WLS binds WNT ligands in the Golgi (Sus scrofa)


name: diphthine-[translation elongation factor 2] + 3 H(+) + 3 S-adenosyl-L-homocysteine => 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + octadecanoate


name: H2O + nitroethane + O2 => acetaldehyde + H(+) + H2O2 + nitrite


name: HSD17B11 dehydrogenates EST17b to E1 (Saccharomyces cerevisiae)


name: PP2A-PP2R5C dephosphorylates MDM2 (Canis familiaris)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Danio rerio)


name: Ca2+ influx into the post-synaptic cell (Drosophila melanogaster)


name: EPCAM binds itself to form homotypic cell adhesion (Sus scrofa)


name: ATP + L-methionine + tRNA(Met) <=> AMP + diphosphate + L-methionyl-tRNA(Met)


name: glutathione disulfide + H(+) + NADH => 2 glutathione + NAD(+)


name: L-phenylalanine(out) + S-methylmercury-L-cysteine(in) = L-phenylalanine(in) + S-methylmercury-L-cysteine(out)


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Xenopus tropicalis)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Homo sapiens)


name: H2O + sn-glycero-3-phosphoethanolamine <=> ethanolamine + H(+) + sn-glycerol 3-phosphate


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Dictyostelium discoideum)


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Rattus norvegicus)


name: ERK5 translocates to the nucleus (Dictyostelium discoideum)


name: RXRA:PPARD binds FABP5:atRA (Caenorhabditis elegans)


name: mitochondrial large ribosomal subunit binding


name: NADSYN1 hexamer amidates NAAD to NAD+ (Caenorhabditis elegans)


name: 2-methoxy-6-all-trans-nonaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine <=> 6-methoxy-3-methyl-2-all-trans-nonaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: anthocyanin A7 + malonyl-CoA <=> anthocyanin A9 + CoA


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Dictyostelium discoideum)


name: NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)


name: TDP(out) + UTP(in) <=> TDP(in) + UTP(out)


name: Dissociation of cytosolic HSF1:HSP90 complex (Gallus gallus)


name: a secondary amine + S-adenosyl-L-methionine = a methylated secondary amine + H(+) + S-adenosyl-L-homocysteine


name: FABP5 dissociates from RXRA:PPARD:atRA (Gallus gallus)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Caenorhabditis elegans)


name: HSBP1 oligomer binds ESRs (Rattus norvegicus)


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Sus scrofa)


name: CRHR1,CRHR2-1 binds CRH,UCN (Homo sapiens)


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)


name: (2E,6E)-farnesyl diphosphate = (-)-alpha-amorphene + diphosphate


name: HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA (Rattus norvegicus)


name: H2O + validoxylamine A 7'-phosphate = phosphate + validoxylamine A


name: "validoxylamine A 7'-phosphate phosphatase"


name: ATP + H(+) + L-tyrosine + NADPH => AMP + diphosphate + L-tyrosinal + NADP(+)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Drosophila melanogaster)


name: Association of procollagen type XIX (Mus musculus)


name: L-lysyl-[protein] + propanoyl-CoA <=> CoA + H(+) + N(6)-propanoyl-L-lysyl-[protein]


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + S-adenosyl-L-methionine <=> griseophenone D + H(+) + S-adenosyl-L-homocysteine


name: 4-O-(beta-D-glucosyl)-(E)-coniferol + A => 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + AH2


name: H2O + oxaloacetate <=> acetate + H(+) + oxalate


name: GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH => GDP-alpha-D-rhamnose + NADP(+)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O => scalarane-17alpha-19-diol


name: (2E,6E)-farnesyl diphosphate => (+)-germacrene D + diphosphate


name: p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Homo sapiens)


name: acetyl-CoA(out) + AMP(in) => acetyl-CoA(in) + AMP(out)


name: N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-homocysteine


name: SRC phosphorylates RUNX3 (Gallus gallus)


name: 3-oxo-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + NADP(+)


name: OAT2 and OAT4 mediate transport of sulphate conjugates (Bos taurus)


name: (11E)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,11E)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + beta-ionone => all-trans-10'-apo-beta-carotenal + O2


name: non-membrane spanning protein tyrosine kinase activity


name: RHOC GAPs stimulate RHOC GTPase activity (Gallus gallus)


name: an N-acylsphingoid base 1-phosphate(in) => an N-acylsphingoid base 1-phosphate(out)


name: [amino-group carrier protein]-C-terminal-L-glutamate + ATP + L-2-aminoadipate <=> [amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ADP + H(+) + phosphate


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Danio rerio)


name: (3R)-hydroxy-5-methylhexanoyl-[ACP] + NADP(+) => 5-methyl-3-oxohexanoyl-[ACP] + H(+) + NADPH


name: NEIL1 cleaves DHU from damaged DNA (Mus musculus)


name: 2-hexadecanoylglycerol + H2O <=> glycerol + H(+) + hexadecanoate


name: 2-dehydro-3-deoxy-L-galactonate + NAD(+) = 3-deoxy-D-glycero-2,5-hexodiulosonate + H(+) + NADH


name: 2 AMP + ATP + 2 H(+) => 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 H2O


name: HIF-alpha translocates from cytosol to nucleus (Caenorhabditis elegans)


name: 2 H(+) + NADH + perillate => H2O + NAD(+) + perillyl aldehyde


name: Assembly of the destruction complex (Homo sapiens)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: ULK3:SUFU dissociates (Drosophila melanogaster)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = a fatty acid + H(+) + sn-glycero-3-phosphoethanolamine


name: RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 (Homo sapiens)


name: 7-oxolithocholate + H(+) + NADH => NAD(+) + ursodeoxycholate


name: (2E,6E,10E)-geranylgeranyl diphosphate + bacteriochlorophyllide a + H(+) <=> diphosphate + geranylgeranyl-bacteriochlorophyllide a


name: AP1G2 binds HGS and CHMP2A (Xenopus tropicalis)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Bos taurus)


name: Casein kinase II phosphorylates PTEN (Dictyostelium discoideum)


name: p-T774-PKN1 phosphorylates PPP1R14A (Rattus norvegicus)


name: ERBB4s80:TAB2:NCOR1 complex translocates to the nucleus (Homo sapiens)


name: 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Mus musculus)


name: a steroid 1,3-dione + AH2 => A + a 1-hydroxy-3-oxo steroid


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O => acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative


name: [fructose-bisphosphate aldolase]-L-lysine + 3 S-adenosyl-L-methionine => [fructose-bisphosphate aldolase]-N(6),N(6),N(6)-trimethyl-L-lysine + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Drosophila melanogaster)


name: 2-phosphoglycerate <=> phosphoenolpyruvate + H2O (Gallus gallus)


name: eNOS:Caveolin-1 complex binds to Nostrin (Rattus norvegicus)


name: mycothiol is oxidized to mycothione (Mycobacterium tuberculosis)


name: 8-hydroxycopalyl diphosphate <=> (13R)-manoyl oxide + diphosphate


name: ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine


name: 15-hydroxypentadecanoyl-CoA + AMP + diphosphate => 15-hydroxypentadecanoate + ATP + CoA


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Rattus norvegicus)


name: DDHD1,2 hydrolyse PA (Dictyostelium discoideum)


name: 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH => 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NADP(+)


name: CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Sus scrofa)


name: 2,5-dihydroxybenzoate + O2 => 3-maleylpyruvate + H(+)


name: MRN complex bound to DNA ends recruits ATM (Mus musculus)


name: Endosome acidification (Schizosaccharomyces pombe)


name: bromide(in) + chloride(out) <=> bromide(out) + chloride(in)


name: 1,2-dihydro-alpha-santonin + NAD(+) => alpha-santonin + H(+) + NADH


name: miR-20 microRNAs bind PTEN mRNA (Homo sapiens)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine-phospho-ribonucleoside in mRNA + H2O <=> (N(7)-methyl 5'-triphospho-guanosine)-guanosine + a 5'-end phospho-ribonucleoside in mRNA + H(+)


name: arginine + glycine => ornithine + guanidoacetate (Mus musculus)


name: AH2 + chermesin D methyl ester => A + asnovolin J


name: Acireductone is oxidized to MOB (Bos taurus)


name: (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Homo sapiens)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Sus scrofa)


name: 2-methylbutanamine + H2O + NAD(+) = 2-methylbutanal + H(+) + NADH + NH4(+)


name: a phenol + acetate + H(+) => a phenyl acetate + H2O


name: L-lysyl(37)-[histone H3] + 3 S-adenosyl-L-methionine => 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(37)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: SFTPA/SFTPD binds TLR2:TLR1 (Homo sapiens)


name: ATM phosphorylates HERC2 (Drosophila melanogaster)


name: "N-terminal amino-acid N(alpha)-acetyltransferase NatA"


name: The phagophore extends from the PIP3-enriched structure (Saccharomyces cerevisiae)


name: (2E)-octenoyl-CoA + H2O => 3-hydroxyoctanoyl-CoA


name: H(+) + sulfate + sulfur + thiosulfate => H2O + tetrathionate


name: PTK2 binds activated EGFR (Canis familiaris)


name: ganglioside GT1b (d18:1(4E)/18:0) + H2O => ganglioside GD1b(d18:1(4E)/18:0) + N-acetylneuraminate


name: L-threonine <=> 2-aminobut-2-enoate + H2O


name: all-trans-beta-carotene + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => all-trans-zeaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: NS1:NS2 (1C:1B) localizes to mitochondria (Homo sapiens)


name: methylcob(III)alamin + S-adenosyl-L-homocysteine => cob(I)alamin + S-adenosyl-L-methionine


name: Keratin filaments bind cell-cell adhesion complexes (Bos taurus)


name: N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity


name: P2Y6 receptor can bind to UDP (Sus scrofa)


name: cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine => 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Sus scrofa)


name: D-cellobiose + H2O <=> beta-D-glucose + D-glucose


name: Binding of ADAR1 homodimer to dsRNA duplex (Homo sapiens)


name: beta-catenin is replaced by repression complexes at the promoter (Rattus norvegicus)


name: HP1 alpha binds Histone H3K9(me)3 (Drosophila melanogaster)


name: a tRNA with a 3' CC end + ATP <=> a tRNA with a 3' CCA end + diphosphate


name: IFNAR1:TYK2 binds TYK2 inhibitors (Sus scrofa)


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Caenorhabditis elegans)


name: Formation of collagen networks (Bos taurus)


name: 2 acetyl-CoA + 5 H(+) + 6 malonyl-CoA <=> 6 CO2 + 8 CoA + H2O + o-orsellinate depside


name: CFTR transports Cl- from cytosol to extracellular region (Homo sapiens)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Canis familiaris)


name: Factor H displaces Bb in Cb:Bb complex (Gallus gallus)


name: H(+) + oxidized [electron-transfer flavoprotein] + valproyl-CoA = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: H(+) + propanoyl-CoA + sulfite => 3-sulfinopropanoyl-CoA + H2O


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Caenorhabditis elegans)


name: H2O + N-docosanoyl-taurine = docosanoate + taurine


name: B-RAF dissociates from S111/S120 p-SPRY2 (Mus musculus)


name: apigenin + UDP-alpha-D-glucose => apigenin 7-O-beta-D-glucoside + H(+) + UDP


name: sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec (Danio rerio)


name: The bound receptor dimerizes (Gallus gallus)


name: PGR binds PGR antagonists (Canis familiaris)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 => (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: nucleotide transmembrane transporter activity


name: alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Homo sapiens)


name: Cleavage of Procaspase‑9 to caspase‑9 (Gallus gallus)


name: TCR binds microbial lipid-based antigen via CD1 (Mus musculus)


name: PTK6 phosphorylates CDKN1B (Danio rerio)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-6-sulfooxy-glucosaminyl derivative + GDP-beta-L-fucose = a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-6-sulfooxy-glucosaminyl derivative + GDP + H(+)


name: granulocyte macrophage colony-stimulating factor complex binding


name: trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP


name: TBC1D14 binds RAB11 and ULK1 (Caenorhabditis elegans)


name: (E)-gamma-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: 4 (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine => 8 AMP + 8 diphosphate + 8 H(+) + PF1022F + 4 S-adenosyl-L-homocysteine


name: NAALADases hydrolyse NAAG (Mus musculus)


name: KCNJ11:ABCC9 binds nicorandil (Mus musculus)


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Rattus norvegicus)


name: ZnT1 mediates the efflux of zinc from the cell (Sus scrofa)


name: cyclohexan-1,2-dione + H2O <=> 6-oxohexanoate + H(+)


name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)


name: 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine = [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: BACH1 translocates from the cytosol to the nucleoplasm (Rattus norvegicus)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Mus musculus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl isothiocyanate + sulfate


name: Dissociation of the Gi alpha:G olf complex (Danio rerio)


name: 3-oxo-L-alanyl-[sulfatase] + 5'-deoxyadenosine + H(+) + L-methionine => L-seryl-[sulfatase] + S-adenosyl-L-methionine


name: AP-2 directly binds some endocytic cargo (Rattus norvegicus)


name: H2O + streptomycin 6-phosphate <=> phosphate + streptomycin


name: CPTP transports C1P from plasma membrane to Golgi membrane (Rattus norvegicus)


name: S-1-propenyl-L-cysteine sulfoxide <=> (E)-prop-1-en-1-SO-peroxol + 2-aminoprop-2-enoate


name: chylomicron remnant + apoE => chylomicron remnant:apoE complex (Rattus norvegicus)


name: 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: CYP3A4 can N-demethylate loperamide (Homo sapiens)


name: 2-methylbutan-1-ol + acetyl-CoA = 2-methylbutyl acetate + CoA


name: H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein] => L-lysyl-[protein] + octanoyl-[ACP]


name: adenosine 5'-phosphosulfate + NH4(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate


name: CysS248-MPST:TXN2 dissociates (Rattus norvegicus)


name: SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors (Homo sapiens)


name: Activation of voltage gated Potassium channels (Gallus gallus)


name: ERBB4s80:STAT5A complex translocates to the nucleus (Xenopus tropicalis)


name: an acyl-CoA + glycine => an N-acylglycine + CoA + H(+)


name: 2-oxoglutarate(out) + taurocholate(in) => 2-oxoglutarate(in) + taurocholate(out)


name: disaccharide transmembrane transporter activity


name: phosphoenolpyruvate + ADP => pyruvate + ATP (Caenorhabditis elegans)


name: Dissociation of cytosolic HSF1:HSP90 complex (Saccharomyces cerevisiae)


name: dimethylallyl diphosphate + quinolinone B <=> diphosphate + peniprequinolone


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Rattus norvegicus)


name: USP18 deubiquitinates TAK1:TAB1 (Gallus gallus)


name: Degradation of TGF-beta receptor complex (Rattus norvegicus)


name: FAS-mediated dimerization of procaspase-8 (Gallus gallus)


name: S-adenosyl-L-methionine + theobromine => caffeine + H(+) + S-adenosyl-L-homocysteine


name: adenosine(in) + 2 Na(+)(in) => adenosine(out) + 2 Na(+)(out)


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Canis familiaris)


name: (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + ML-236A carboxylate <=> holo-[2-methylbutanoate polyketide synthase] + mevinic carboxylate


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Rattus norvegicus)


name: Retromer associates with WLS (Canis familiaris)


name: H2O + N-(15Z-tetracosenoyl)-ethanolamine => (15Z)-tetracosenoate + ethanolamine


name: laricitrin + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + syringetin


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Mus musculus)


name: YKI binds to HTH and TSH and activates transcription (Drosophila melanogaster)


name: dehydroepiandrosterone 3-sulfate(in) + propanoate(out) => dehydroepiandrosterone 3-sulfate(out) + propanoate(in)


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Sus scrofa)


name: (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose => (20S)-ginsenoside F2 + H(+) + UDP


name: H2O + L-cysteinyl-tRNA(Cys) <=> H(+) + L-cysteine + tRNA(Cys)


name: 4-aminobenzoate 3,4-dioxygenase (deaminating) activity


name: eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Homo sapiens)


name: p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 (Homo sapiens)


name: EXT1:EXT2 transfer GlcNAc to the heparan chain (Canis familiaris)


name: an inositol-1-phosphophytoceramide + GDP-alpha-D-mannose = a mannosylinositol-1-phosphophytoceramide + GDP + H(+)


name: a fatty acid methyl ester + S-adenosyl-L-homocysteine => a fatty acid + S-adenosyl-L-methionine


name: CYP26C1 4-hydroxylates 9cRA (Mus musculus)


name: a ganglioside GM3 + N-acetylneuraminate => a ganglioside GD3 + H2O


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Rattus norvegicus)


name: Collagen type VII degradation by MMP1,2,3 (Sus scrofa)


name: ATP12A:ATP4B exchanges K+ for H+ (Homo sapiens)


name: 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP => 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP


name: Proteasome-mediated degradation of PolyUb-FBXL7 (Rattus norvegicus)


name: MARK3 phosphorylates KSR1 (Rattus norvegicus)


name: an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate => an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O


name: 2-oxoglutarate + dodecyl sulfate + O2 = CO2 + dodecanal + H(+) + succinate + sulfate


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Caenorhabditis elegans)


name: hexanal + hydrogen cyanide => (2S)-2-hydroxyheptanenitrile


name: Cleavage of p-STK3 (p-MST2) by caspase 3 (Caenorhabditis elegans)


name: 1,3,7-trimethylurate + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + theacrine


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Plasmodium falciparum)


name: aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH4(+) = H(+) + 4 H2O + phosphate + pyridoxal 5'-phosphate


name: H2O + N-hexadecanoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: lipo-PDH decarboxylates PYR to Ac-CoA (Saccharomyces cerevisiae)


name: RHOQ binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: Phosphorylation of STAT2 (Gallus gallus)


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O <=> (N(2),N(2),N(7))-trimethyl-GMP + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+)


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Caenorhabditis elegans)


name: PIAS4 SUMOylates VHL with SUMO1 (Bos taurus)


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Canis familiaris)


name: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+)


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Canis familiaris)


name: 2 bilirubin IXalpha + O2 => 2 biliverdin IXalpha + 2 H2O


name: H2O + L-methionyl-S-oxide-[protein] + NADP(+) => H(+) + L-methionyl-[protein] + NADPH + O2


name: IL24 binds to IL22RA1:JAK1:IL20RB (Gallus gallus)


name: NEU2 hydrolyzes Neu5Ac from glycoconjugates (Canis familiaris)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Xenopus tropicalis)


name: Activated FGFR4:p-FRS binds GRB2:SOS1 (Sus scrofa)


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Xenopus tropicalis)


name: CYB5A:heme reduces Asc.- to AscH- (Schizosaccharomyces pombe)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Sus scrofa)


name: TP53 forms homotetramers (Drosophila melanogaster)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Rattus norvegicus)


name: GRK1,4,7 phosphorylate MII to p-MII (Caenorhabditis elegans)


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Canis familiaris)


name: RHOD GAPs stimulate RHOD GTPase activity (Gallus gallus)


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Canis familiaris)


name: H2O + methylamine + NAD(+) <=> formaldehyde + H(+) + NADH + NH4(+)


name: chlorothalonil + H2O = 4-hydroxychlorothalonil + chloride + 2 H(+)


name: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) => 3,4-dihydroxybenzoate + CO2 + NADH


name: 26S proteasome degrades PolyUb-RUNX2 (Drosophila melanogaster)


name: 2 2-oxoglutarate + a (3R)-3-[(carboxymethyl)amino]fatty acid + 2 O2 = a (3R)-3-isocyanyl-fatty acid + 3 CO2 + 2 H2O + 2 succinate


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Bos taurus)


name: Activated PKC phosphorylates SHC1 (Drosophila melanogaster)


name: PLEKHA3,8 bind PI4P, ARF1 (Drosophila melanogaster)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O <=> (9Z)-octadecenoate + 1,3-dihexadecanoylglycerol + H(+)


name: 20-hydroxy-lipoxin B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => lipoxin B4 + O2 + reduced [NADPH--hemoprotein reductase]


name: HSD17B13 binds lipid droplets (Xenopus tropicalis)


name: D-lysine(in) + L-ornithine(out) <=> D-lysine(out) + L-ornithine(in)


name: PPM1F dephosphorylates p-T286-CaMKII (Homo sapiens)


name: ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oryzalexin E + oxidized [NADPH--hemoprotein reductase]


name: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 <=> (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H(+) + 2 H2O


name: CYP17A1 17-hydroxylates PREG (Bos taurus)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Canis familiaris)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Mus musculus)


name: 2-oxoadipate + glycine => glyoxylate + L-2-aminoadipate


name: 10-hydroxy-(11S,12S)-epoxy- (5Z,8Z,14Z)-eicosatrienoate + H2O <=> (10,11S,12R)-trihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: DDAH1,2 hydrolyses ADMA to DMA and L-Cit (Homo sapiens)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Rattus norvegicus)


name: ESPL1 (Separase) cleaves centromeric cohesin (Xenopus tropicalis)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Bos taurus)


name: Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)


name: Mevalonate-5-phosphate is further phosphorylated. (Sus scrofa)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Rattus norvegicus)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Danio rerio)


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: NBR1 binds MAP1LC3B (Dictyostelium discoideum)


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Bos taurus)


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Drosophila melanogaster)


name: TXNIP binds reduced thioredoxin (Saccharomyces cerevisiae)


name: glycoursodeoxycholate(out) + 2 Na(+)(out) => glycoursodeoxycholate(in) + 2 Na(+)(in)


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A <=> a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate)


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Rattus norvegicus)


name: ent-copalyl diphosphate = diphosphate + ent-sandaracopimara-8(14),15-diene


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Bos taurus)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Sus scrofa)


name: NADP(+) + trypanothione <=> H(+) + NADPH + trypanothione disulfide


name: 2-ethyl-L-serine <=> (2S)-2-aminobutanoate + formaldehyde


name: a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA


name: DKK promotes clathrin-dependent internalization of LRP6 (Xenopus tropicalis)


name: Caspase cleavage of DCC (Xenopus tropicalis)


name: dTDP-6-deoxy-beta-L-talose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH


name: PROT mediates L-proline uptake (Homo sapiens)


name: 5,6-dihydrouridine(20b) in tRNA + NADP(+) => H(+) + NADPH + uridine(20b) in tRNA


name: L-phenylalanine(out) + L-serine(in) <=> L-phenylalanine(in) + L-serine(out)


name: cortisone + NAD(+) <=> 17alpha-hydroxypregn-4-en-3,11,20-trione-21-al + H(+) + NADH


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] => 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + L-alanine + L-anticapsin <=> ADP + bacilysin + H(+) + phosphate


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)


name: 1D-myo-inositol 1-phosphate + H2O <=> myo-inositol + phosphate


name: 1,2-didecanoyl-sn-glycerol + ATP = 1,2-didecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: CoA + H(+) + N(2')-acetylgentamicin C1a => acetyl-CoA + gentamicin C1a


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Caenorhabditis elegans)


name: LIMK phosphorylates CFL1, inactivating it (Homo sapiens)


name: L-alanine(in) + L-phenylalanine(out) = L-alanine(out) + L-phenylalanine(in)


name: 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate => L-glutamine + scyllo-inosose


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Sus scrofa)


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: Na+/H+ exchanger transport (at cell membrane) (Rattus norvegicus)


name: H(+) + H2O + maniladiol + oxidized [NADPH--hemoprotein reductase] => beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase]


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Caenorhabditis elegans)


name: (S)-2,3-epoxysqualene + H2O => dammarenediol-II


name: H2O + N-(11Z-eicosenoyl)-sphinganine => (11Z)-eicosenoate + sphinganine


name: GTSE1 promotes translocation of TP53 to the cytosol (Canis familiaris)


name: Caspase 3-mediated cleavage of PKC delta (Gallus gallus)


name: 1beta-hydroxydeoxycholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => deoxycholate + O2 + reduced [NADPH--hemoprotein reductase]


name: Mitochondrial FPGS-1 transforms THF to THFPG (Canis familiaris)


name: E-cadherin degradation by MMP9, KLK7 (Danio rerio)


name: ADP + H(+) + N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein] => ATP + N(6)-(D-erythrulosyl)-L-lysyl-[protein]


name: L-galactonate = 2-dehydro-3-deoxy-L-galactonate + H2O


name: Formation of the P-TEFb(Cyclin T1:Cdk9) complex (Homo sapiens)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Bos taurus)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Dictyostelium discoideum)


name: CRYM reduces P2C to PPCA (Schizosaccharomyces pombe)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Sus scrofa)


name: H(+) + N(omega)-methyl-L-arginine + 2 NADH + 3 O2 = 3 H2O + N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + 2 NAD(+)


name: carbamoyl phosphate + putrescine => H(+) + N-carbamoylputrescine + phosphate


name: PAF receptor binds platelet activating factor (Danio rerio)


name: TIRAP binds PIP2-rich regions in the plasma membrane (Xenopus tropicalis)


name: phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] <=> (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit]


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Bos taurus)


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Xenopus tropicalis)


name: aldehydo-D-ribose 5-phosphate => D-ribose 5-phosphate


name: beta-tocopherol + H(+) + S-adenosyl-L-homocysteine => delta-tocopherol + S-adenosyl-L-methionine


name: all-trans-zeaxanthin + 2 UDP-alpha-D-glucose = 2 H(+) + 2 UDP + zeaxanthin bis(beta-D-glucoside)


name: Pro-beta-NGF and mature beta-NGF are secreted (Canis familiaris)


name: 2 Fe(III)-[cytochrome c] + H2O + nitrite => 2 Fe(II)-[cytochrome c] + H(+) + nitroxyl + O2


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Danio rerio)


name: PIAS1 SUMOylates SATB2 with SUMO3 (Homo sapiens)


name: GDIs block activation of RHOA (Bos taurus)


name: 5,10-dihydrophenazine + O2 => H2O2 + phenazine


name: THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 (Drosophila melanogaster)


name: MRE11 binds cytosolic DNA (Mus musculus)


name: 7-hydroxymethyl chlorophyll a reductase activity


name: Translocation of NFATC1:CaN:CaM to nucleus (Canis familiaris)


name: JMJD6 demethylates Me2R3-histone H3 (Mus musculus)


name: VANGL2 is phosphorylated in response to WNT5A (Homo sapiens)


name: JAK1-activated RAF1 phosphorylates MAPKs (Mus musculus)


name: Mcm2-7 is phosphorylated by DDK (Sus scrofa)


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Bos taurus)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Homo sapiens)


name: arginine + glycine => ornithine + guanidoacetate (Rattus norvegicus)


name: 26S proteosome degrades ODC holoenzyme complex (Drosophila melanogaster)


name: (4R)-hydroxysphinganine + hexadecanoate => H2O + N-hexadecanoyl-(4R)-hydroxysphinganine


name: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) <=> 3-methylcatechol + CO2 + NADH


name: 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+) => 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2


name: Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure (Bos taurus)


name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Caenorhabditis elegans)


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Dictyostelium discoideum)


name: D-serine(in) + L-glutamine(out) + Na(+)(out) = D-serine(out) + L-glutamine(in) + Na(+)(in)


name: 2-oxoglutarate(in) + prostaglandin F2alpha(out) = 2-oxoglutarate(out) + prostaglandin F2alpha(in)


name: (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O <=> resolvin E1


name: (R)-2-hydroxy-3-methylbutyrate + NADP(+) => 3-methyl-2-oxobutanoate + H(+) + NADPH


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphocholine => 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Drosophila melanogaster)


name: TRPV1 binds TRPV1 agonists (Drosophila melanogaster)


name: Formation of eIF2:GDP:eIF2B intermediate (Dictyostelium discoideum)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ATP + L-glutamate = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + H(+) + phosphate


name: JAK1 phosphorylates STAT3,STAT6 (Gallus gallus)


name: CRYM reduces P2C to PPCA (Dictyostelium discoideum)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Gallus gallus)


name: Translocation of DFF to the nucleus (Rattus norvegicus)


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Mus musculus)


name: 2-dehydro-3-deoxy-D-gluconate + NADP(+) => (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH


name: sucrose + UDP-alpha-D-galactose = H(+) + loliose + UDP


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Rattus norvegicus)


name: p-S216-CDC25C translocates to the cytosol (Caenorhabditis elegans)


name: 3-methyl fatty acid + ATP + CoA = a 3-methyl fatty acyl-CoA + AMP + diphosphate


name: poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Xenopus tropicalis)


name: PDCL releases folded G-beta from TRiC/CCT (Bos taurus)


name: prostaglandin F2alpha(in) => prostaglandin F2alpha(out)


name: diphosphate + P(1),P(4)-bis(5'-guanosyl) tetraphosphate => 2 GTP + H(+)


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Danio rerio)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Sus scrofa)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Xenopus tropicalis)


name: ATP + H2O + pheophorbide a(in) <=> ADP + H(+) + pheophorbide a(out) + phosphate


name: diacetylchitobiose-6'-phosphate + H2O = acetate + N'-monoacetylchitobiose-6'-phosphate


name: H(+)(out) + L-lysine(out) = H(+)(in) + L-lysine(in)


name: XIAP dissociates from ub-TLE (Drosophila melanogaster)


name: FITM1, FITM2 bind TAGs (Caenorhabditis elegans)


name: L-galactonate + NAD(+) => H(+) + keto-D-tagaturonate + NADH


name: an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + H(+) + lactate


name: E2F6 binds BRCA1 gene promoter (Homo sapiens)


name: H2O + N-(9Z-octadecenoyl)-L-serine = (9Z)-octadecenoate + L-serine


name: ZnT1 mediates the efflux of zinc from the cell (Gallus gallus)


name: SRD5A3 reduces pPNOL to DCHOL (Gallus gallus)


name: salicyl alcohol + UDP-alpha-D-glucose = H(+) + salicin + UDP


name: (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+) => 1,2,3-trihydroxybenzene + O2


name: 1,2-didecanoyl-sn-glycerol + CDP-choline => 1,2-didecanoyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Canis familiaris)


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Xenopus tropicalis)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Sus scrofa)


name: HOMER binds SHANK proteins (Homo sapiens)


name: 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 8-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase]


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Rattus norvegicus)


name: adenosine(9) in tRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine


name: (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = all-trans-decaprenyl diphosphate + 7 diphosphate


name: vascular endothelial growth factor receptor binding


name: Association of Rb with Cyclin E:Cdk2 complexes (Rattus norvegicus)


name: (R)-salsolinol + S-adenosyl-L-methionine => H(+) + N-methyl-(R)-salsolinol + S-adenosyl-L-homocysteine


name: Importin-8 binds AGO2:miRNA (Drosophila melanogaster)


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> 5-epi-alpha-selinene + diphosphate


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Bos taurus)


name: 7-isopropyl-4-methyloxepan-2-one + H2O <=> 6-hydroxy-3,7-dimethyloctanoate + H(+)


name: 2 AH2 + all-trans-zeaxanthin + 2 O2 <=> 2 A + all-trans-adonixanthin + 3 H2O


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Bos taurus)


name: H2O + isochorismate = (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate


name: taurolithocholate + PAPS => taurolithocholate sulfate + PAP (Drosophila melanogaster)


name: SARDH:FAD oxidatively demethylates SARC to Gly (Canis familiaris)


name: Expression of RIPPLY2 in presomitic mesoderm (Homo sapiens)


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Rattus norvegicus)


name: TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Sus scrofa)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Mus musculus)


name: HTR1 and 5A receptors can bind serotonin (Homo sapiens)


name: L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] <=> H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)


name: 2''-O-tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide => H2O + N(6)-tetradecanoyl-L-lysyl-[protein] + NAD(+)


name: hexadecanoyl-CoA + tetradecan-1-ol <=> CoA + tetradecanyl hexadecanoate


name: PIAS3 SUMOylates MITF with SUMO1 (Xenopus tropicalis)


name: a 16-oxosteroid + H(+) + NADPH => a 16alpha-hydroxysteroid + NADP(+)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Xenopus tropicalis)


name: ethylenediaminetriacetate + FMNH2 + O2 <=> ethylenediaminediacetate + FMN + glyoxylate + H(+) + H2O


name: 21-hydroxyprogesterone + H(+) + NADH => 4-pregnen-20,21-diol-3-one + NAD(+)


name: Constitutive phosphorylation by GSK3 (Gallus gallus)


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Saccharomyces cerevisiae)


name: ASAP1 stimulates GTPase activity of ARF4 (Mus musculus)


name: Recruitment of TRAF6/TRAF2 to IPS-1 (Homo sapiens)


name: (R)-lactate + NAD(+) <=> H(+) + NADH + pyruvate


name: diphosphate + nerylneryl diphosphate => (2Z,6Z)-farnesyl diphosphate + isopentenyl diphosphate


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Gallus gallus)


name: H2O + N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine = H(+) + N-hexadecanoylsphing-4-enine + phosphocholine


name: Methylation of N-acetyl-5-HT to form melatonin (Dictyostelium discoideum)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Saccharomyces cerevisiae)


name: Transhomodimerization of Nectins (Homo sapiens)


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Canis familiaris)


name: JAK2-activated MAPKs phosphorylate YBX1 (Homo sapiens)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Gallus gallus)


name: a beta-D-galactoside + acetyl-CoA = a 6-acetyl-beta-D-galactoside + CoA


name: Association of procollagen type XV (Mus musculus)


name: SMAD2/3:SMAD4 heterotrimer binds SP1 (Rattus norvegicus)


name: (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + O2 => (3R,6R)-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: H(+) + L-proline betaine + NADPH + O2 <=> formaldehyde + H2O + N-methyl-L-proline + NADP(+)


name: Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Danio rerio)


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Xenopus tropicalis)


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O <=> a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphate


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Schizosaccharomyces pombe)


name: (2S)-2-amino-3-oxobutanoate + CoA => acetyl-CoA + glycine


name: (9Z)-octadecenoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA


name: Polyubiquitinated NRIF migrates to the nucleus (Gallus gallus)


name: 2 a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADH => H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+)


name: Release of Cytochrome c from mitochondria (Canis familiaris)


name: L-kynurenine(out) + L-tryptophan(in) <=> L-kynurenine(in) + L-tryptophan(out)


name: beta-alanine + histamine => carcinine + H2O


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Bos taurus)


name: ROCK phosphorylates LIMK1,2 (Homo sapiens)


name: (3R)-hydroxy-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA => (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H2O


name: NUDT16 hydrolyses dIDP to dIMP (Danio rerio)


name: (Z)-3-ureidoacrylate + H(+) + H2O => (Z)-3-aminoacrylate + CO2 + NH4(+)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Bos taurus)


name: PTK6 phosphorylates STAP2 (Mus musculus)


name: H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate


name: PDPK1 phosphorylates SGK1 (Homo sapiens)


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Rattus norvegicus)


name: RUNX3:CBFB binds the ITGAL gene,(ITGA4 gene) promoter (Homo sapiens)


name: Translocation of NFATC1:CaN:CaM to nucleus (Plasmodium falciparum)


name: SLC51A:SLC51B transports bile salts from cytosol to extracellular region (Mus musculus)


name: Collagen type XII degradation by MMP12 (Bos taurus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: D-aspartate + H2O + O2 = H2O2 + NH4(+) + oxaloacetate


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Danio rerio)


name: Phosphorylation of L1 by ERK (Dictyostelium discoideum)


name: USP7 deubiquitinates monoubiquitinated PTEN (Sus scrofa)


name: Tetramerization of procollagen VI (Mus musculus)


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O => (14S,15S)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: TTLLs polyglutamylate tubulin (Bos taurus)


name: Glucagon-like Peptide 1 is secreted from intestinal L cells (Canis familiaris)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Rattus norvegicus)


name: Translocation of PDK1 to Plasma membrane (Bos taurus)


name: Interleukin-27 binds Interleukin-27 receptor (Bos taurus)


name: (S)-methylmalonyl-CoA + H(+)(out) + Na(+)(in) => CO2 + Na(+)(out) + propanoyl-CoA


name: 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione => 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O


name: 2 Fe(III)-[cytochrome c] + H2O + pseudooxynicotine => 4-oxo-4-(pyridin-3-yl)butanal + 2 Fe(II)-[cytochrome c] + 2 H(+) + methylamine


name: cathenamine + H(+) = 4,21-dehydrogeissoschizine


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([2-N-acetyl-alpha-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Drosophila melanogaster)


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Xenopus tropicalis)


name: ATP + CoA + OPC-6 <=> AMP + diphosphate + OPC-6-CoA


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + cholesterol <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z,12Z)-octadecadienoate


name: (5E)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,5E)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: (2Z,4E)-2-aminomuconate + H2O <=> (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH4(+)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Canis familiaris)


name: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate


name: sphing-4-enine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoyl-sphing-4-enine


name: p-STAT1:p-STAT4 translocates to the nucleus (Mus musculus)


name: CYP11B2 18-hydroxylates CORST to 18HCORST (Homo sapiens)


name: TPX2 binds AURKA at centrosomes (Bos taurus)


name: beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose => alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP + H(+)


name: sn-glycerol 3-phosphate + tetradecanoyl-CoA => 1-tetradecanoyl-sn-glycerol 3-phosphate + CoA


name: ANKH transports PPi from cytosol to extracellular region (Gallus gallus)


name: ERBB2 KD mutants heterodimerize (Homo sapiens)


name: G-protein coupled bile acid receptor binds lithocholic acid (Drosophila melanogaster)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dUMP


name: AMP + diphosphate + H(+) + holo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] => apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + ATP + biotin


name: formaldehyde + glycine + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin] => H2O + oxidized 2[4Fe-4S]-[ferredoxin] + sarcosine


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Bos taurus)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Bos taurus)


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Homo sapiens)


name: Cleavage of ethenoadenine by MPG glycosylase (Sus scrofa)


name: all-trans-4,4'-diapophytofluene + FAD + H(+) <=> all-trans-4,4'-diapo-zeta-carotene + FADH2


name: GLB1 hydrolyses linker chain(2) (Rattus norvegicus)


name: 9-riburonosyladenine + H(+) + H2O2 => 5'-dehydroadenosine + H2O + O2


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 O2 => 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + 2 succinate


name: SEPHS2 phosphorylates H2Se to form SELP (Caenorhabditis elegans)


name: asperaculane E + O2 + reduced [NADPH--hemoprotein reductase] = asperaculane G + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Bos taurus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Canis familiaris)


name: a ganglioside GD1b + H2O <=> a ganglioside GM1 + N-acetylneuraminate


name: Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation (Homo sapiens)


name: PRMT6 methylates histone H2A arginine-30 (H2AR29) (Homo sapiens)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Gallus gallus)


name: MLCL transports from the IM to the ER (Homo sapiens)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Canis familiaris)


name: H2O + tetradecanoyl-[ACP] <=> H(+) + holo-[ACP] + tetradecanoate


name: Calmodulin dissociates KRAS4B from the plasma membrane (Canis familiaris)


name: Excision of FapyG by OGG1 glycosylase (Dictyostelium discoideum)


name: Initial activation of proMMP2 by MMP1, 7 (Mus musculus)


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Sus scrofa)


name: 5,10-methylenetetrahydromethanopterin + NAD(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Bos taurus)


name: H2O + NAD(+) + succinate semialdehyde = 2 H(+) + NADH + succinate


name: ATP + pyridoxal = ADP + H(+) + pyridoxal 5'-phosphate


name: PTPN1 and PTPN2 dephosphorylate MET (Mus musculus)


name: ERBB4 forms heterodimers with EGFR (Drosophila melanogaster)


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Rattus norvegicus)


name: choriogonadotropin hormone receptor activity


name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 2 L-glutamate + NAD(+) <=> 2-oxoglutarate + H(+) + L-glutamine + NADH


name: C3PO hydrolyzes cleaved passenger strand (Mus musculus)


name: H2O + oxidized 2[4Fe-4S]-[ferredoxin] + sarcosine => formaldehyde + glycine + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: ADP + H(+) + N-acetyl-alpha-D-muramate 1-phosphate => ATP + N-acetyl-D-muramate


name: (2E,6E)-farnesyl diphosphate + H2O => (6E)-nerolidol + diphosphate


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)


name: PTEN dephosphorylates PIP3 (Caenorhabditis elegans)


name: 1-(9Z,12Z-octadecadienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: IDO2 dioxygenates L-Trp to NFK (Canis familiaris)


name: RRAGA,B exchanges GDP for GTP (Xenopus tropicalis)


name: ATP + H2O + hydrogenselenide = AMP + 2 H(+) + phosphate + selenophosphate


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Canis familiaris)


name: Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Canis familiaris)


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Homo sapiens)


name: Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Mus musculus)


name: UDP-alpha-D-glucuronate + zolasartan = UDP + zolarsartan-2-N-beta-D-glucuronide


name: an N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP => a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Rattus norvegicus)


name: acetyl-CoA + H2O => acetate + CoASH (Sus scrofa)


name: (7R,8S)-8-amino-7-(carboxyamino)nonanoate + ATP = (4R,5S)-dethiobiotin + ADP + H(+) + phosphate


name: ABCA12 transports lipids from cytosol to extracellular region (Plasmodium falciparum)


name: atROL binds to RBP2 (Xenopus tropicalis)


name: an anthocyanidin 3-O-beta-D-glucoside + malonyl-CoA = an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: benzene-1,2,4-triol + FAD + H(+) + H2O => FADH2 + O2 + resorcinol


name: diphosphate + NADP(+) + squalene => H(+) + NADPH + presqualene diphosphate


name: 5-methylcytidine(38) in tRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(38) in tRNA + S-adenosyl-L-methionine


name: (2S)-2-aminobutanoate + 3-phenylpyruvate => 2-oxobutanoate + L-phenylalanine


name: NMT1/2 transfer MYS to GNAT1 (Bos taurus)


name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate (Homo sapiens)


name: (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H(+) + NADPH => (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + NADP(+)


name: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + H(+) + S-adenosyl-L-homocysteine


name: a long-chain fatty acyl-CoA + a sterol <=> a sterol ester + CoA


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Homo sapiens)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Homo sapiens)


name: AH2 + hercynyl-SeGlcNAc selenoxide <=> 2-acetamidoglucal + A + H2O + selenoneine


name: SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Rattus norvegicus)


name: (2S)-2-hydroxy-2-(3-methoxyphenyl)acetonitrile => 3-methoxybenzaldehyde + hydrogen cyanide


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Rattus norvegicus)


name: Unknown caspase cleaves NTRK3 (Homo sapiens)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-guanosine) in mRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine


name: (-)-pluviatolide + S-adenosyl-L-methionine <=> (-)-bursehernin + H(+) + S-adenosyl-L-homocysteine


name: Cytosolic PLK1 translocates to the nucleus (Rattus norvegicus)


name: Activated protein C:PROCR binds F2R (Homo sapiens)


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Drosophila melanogaster)


name: MAOB inhibitors bind MAOB:FAD (Xenopus tropicalis)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Bos taurus)


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Gallus gallus)


name: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Rattus norvegicus)


name: Activation of Ca impermeable AMPA receptors (Canis familiaris)


name: AFG3L2 binds mitochondrial matrix proteins (Danio rerio)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Saccharomyces cerevisiae)


name: chloride(in) + 2 Na(+)(in) + O-butanoyl-(R)-carnitine(in) => chloride(out) + 2 Na(+)(out) + O-butanoyl-(R)-carnitine(out)


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Drosophila melanogaster)


name: phosphate + xanthosine = alpha-D-ribose 1-phosphate + xanthine


name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Bos taurus)


name: Activated FGFR1 phosphorylates PLCG1 (Caenorhabditis elegans)


name: AZD1979 + H2O = AZD1979 oxetane hydrolysis product + H(+)


name: Glucagon binds to Glucagon receptor (Mus musculus)


name: adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine => 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine


name: p-STAT1 dissociates from IL6ST:IL6ST (Homo sapiens)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Drosophila melanogaster)


name: (2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate => diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + D-galactose => a globoside Gb3Cer (d18:1(4E)) + H2O


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Sus scrofa)


name: PRKN polyubiquitinates RIPK3 (Bos taurus)


name: H(+)(out) + nitrite(in) <=> H(+)(in) + nitrite(out)


name: Agmatine + H2O <=> putrescine + urea (Sus scrofa)


name: SRD5A1 dehydrogenates TEST to DHTEST (Danio rerio)


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Gallus gallus)


name: H2O + N-(4-aminobenzoyl)-L-glutamate <=> 4-aminobenzoate + L-glutamate


name: LARG activation by G alpha 12/13 (Rattus norvegicus)


name: H2O + L-tyrosine + O2 <=> 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Homo sapiens)


name: a purine D-ribonucleoside + H2O => a purine nucleobase + D-ribose


name: TNFSF15 binds TNFRSF25 (Rattus norvegicus)


name: (12R)-hydroxy-(9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphocholine => (12R-hydroxy-9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: UDP-alpha-D-glucuronate + wogonin => UDP + wogonin 7-O-beta-D-glucuronate


name: MMP2, MMP7, MMP9 bind CD44 (Mus musculus)


name: mitogen-activated protein kinase kinase kinase kinase binding


name: HEXA cleaves the terminal GalNAc from small HA fragments (Dictyostelium discoideum)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Sus scrofa)


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Mus musculus)


name: ATP4A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)


name: acetyl-CoA + 2 AH2 + 9 H(+) + malate + 6 malonyl-CoA + 5 NADPH + 2 S-adenosyl-L-methionine = 2 A + 6 CO2 + 7 CoA + 6 H2O + 5 NADP(+) + 2 S-adenosyl-L-homocysteine + trihazone A


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ATP + erythritol = ADP + D-erythritol 1-phosphate + H(+)


name: "erythritol kinase (D-erythritol 1-phosphate-forming)"


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Mus musculus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Homo sapiens)


name: D-glucose + DIMBOA => DIMBOA beta-D-glucoside + H2O


name: SALL4 recruits NuRD to PTEN gene (Bos taurus)


name: guanosine 3'-diphosphate 5'-triphosphate + H2O <=> guanosine 3',5'-bis(diphosphate) + H(+) + phosphate


name: SLC19A2/3 transport extracellular THMN to cytosol (Dictyostelium discoideum)


name: AH2 + O2 + phylloquinone <=> 2,3-epoxyphylloquinone + A + H2O


name: CSNK1A1 and ADRBK1 dissociate from p-SMO dimer (Drosophila melanogaster)


name: Translocation of BMF to mitochondria (Rattus norvegicus)


name: 2 H(+) + O2 + octadecanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] = (9Z)-octadecenoyl-CoA + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ub UBXN7 is degraded by the 26S proteasome (Bos taurus)


name: RET tyrosine phosphorylation (Sus scrofa)


name: HCMV Nuclear Pore Docking (Homo sapiens)


name: Syndecan-1 binds fibronectin (Bos taurus)


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Rattus norvegicus)


name: Signal peptidase hydrolyzes preproGLP-1 to proGLP-1 (Homo sapiens)


name: H(+) + NAD(+) + 2 reduced [2Fe-2S]-[putidaredoxin] => NADH + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: ATP + N-hexanoyl-(4R)-hydroxysphinganine => ADP + H(+) + N-hexanoyl-(4R)-hydroxysphinganine-1-phosphate


name: Integrin alpha4beta1 binds JAM2:JAM3 (Gallus gallus)


name: H(+) + S-adenosyl-L-homocysteine + ubiquinol-6 => 3-demethylubiquinol-6 + S-adenosyl-L-methionine


name: hexan-2-one + hydrogen cyanide => (2S)-2-hydroxy-2-methylhexanenitrile


name: (3R)-hydroxyoctanoyl-[ACP] + NADP(+) => 3-oxooctanoyl-[ACP] + H(+) + NADPH


name: 9-cis-retinal + H2O + NAD(+) <=> 9-cis-retinoate + 2 H(+) + NADH


name: 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + phosphate => 1D-myo-inositol hexakisphosphate + H2O


name: 3-hydroxypropanoate + 2 H(+) + NADH => 3-hydroxypropanal + H2O + NAD(+)


name: USP20, USP33 deubiquitinate ADRB2 (Sus scrofa)


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + 6 CO2 + 7 CoA + H2O => acetyl-CoA + 4 H(+) + 6 malonyl-CoA


name: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(27)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(27)-[histone H3] + succinate


name: Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Dictyostelium discoideum)


name: Activated FGFR1 binds PLCG1 (Drosophila melanogaster)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Rattus norvegicus)


name: NEIL3 cleaves spiroiminodihydantoin (Xenopus tropicalis)


name: 2-iodophenol + S-adenosyl-L-methionine <=> 1-iodo-2-methoxybenzene + H(+) + S-adenosyl-L-homocysteine


name: 5-hydroxypentan-2-amine + H2O + NAD(+) = 5-hydroxypentan-2-one + H(+) + NADH + NH4(+)


name: Pks5 transforms LFCA adenylate ester to mycocerosyl (Mycobacterium tuberculosis)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Bos taurus)


name: Translocation of peptide bound MHC class I complex to cell surface (Mus musculus)


name: Transport (influx) of bile salts and acids by OATP-A (Bos taurus)


name: Factor B binds to surface-associated C3b (Xenopus tropicalis)


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Sus scrofa)


name: Aggresome dissociates from dynein and microtubule (Bos taurus)


name: IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Homo sapiens)


name: fibroblast growth factor receptor activity


name: PIAS3 SUMOylates PGR with SUMO1 (Bos taurus)


name: TRiC/CCT binds unfolded G-protein beta subunit (Sus scrofa)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + tetradecanoyl-CoA => 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Canis familiaris)


name: a carboxylic ester + H2O = a carboxylate + an alcohol + H(+)


name: H(+)(in) + N-(4-aminobenzoyl)-L-glutamate(in) <=> H(+)(out) + N-(4-aminobenzoyl)-L-glutamate(out)


name: Exocytosis of ficolin-rich granule membrane proteins (Schizosaccharomyces pombe)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Canis familiaris)


name: Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)


name: HSPG binds LPL dimer (Rattus norvegicus)


name: glycine(out) + n H(+)(in) => glycine(in) + n H(+)(out)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + hexadecanoyl-CoA => 1-O-hexadecyl-2-acetyl-3-hexadecanoyl-sn-glycerol + CoA


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Schizosaccharomyces pombe)


name: ATP + butanoyl-CoA + hydrogencarbonate = (2R)-ethylmalonyl-CoA + ADP + H(+) + phosphate


name: H2O + kynurenate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + L-kynurenine


name: H2O + sphing-4-enine-phosphocholine => choline + H(+) + sphing-4-enine 1-phosphate


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: UBA1 adenylates ubiquitin in the cytosol (Caenorhabditis elegans)


name: Activated TLR4:TICAM1 recruits TRAF6 (Homo sapiens)


name: p-S10 CDKN1B translocates to the cytosol (Drosophila melanogaster)


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Drosophila melanogaster)


name: LTD4 is converted to LTE4 by DPEP1/2 (Canis familiaris)


name: TP73 tetramer translocates to the nucleus (Sus scrofa)


name: beta-alanine(out) + chloride(out) + 2 Na(+)(out) <=> beta-alanine(in) + chloride(in) + 2 Na(+)(in)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Schizosaccharomyces pombe)


name: L-arginine(out) + L-histidine(in) + Na(+)(in) => L-arginine(in) + L-histidine(out) + Na(+)(out)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Gallus gallus)


name: 3-methyl-(2E)-butenoyl-CoA + ATP + hydrogencarbonate => 3-methyl-(2E)-glutaconyl-CoA + ADP + H(+) + phosphate


name: FLVCR1-1 transports heme from cytosol to extracellular region (Mus musculus)


name: (2R,3S)-beta-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O


name: (R)-carnitine + crotonobetainyl-CoA = (R)-carnitinyl-CoA + crotonobetaine


name: Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions (Danio rerio)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Saccharomyces cerevisiae)


name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Canis familiaris)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Mus musculus)


name: BCHE hydrolyzes ASA- (Drosophila melanogaster)


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Caenorhabditis elegans)


name: a (Z)-alkenyl glucosinolate + H2O => a (Z)-N-(sulfonatooxy)alkenimidothioate + D-glucose + H(+)


name: Movement of clathrin coated vesicles into early endosome (Caenorhabditis elegans)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP + CoA


name: NEIL1 cleaves DHU from damaged DNA (Danio rerio)


name: Hikeshi binds HSP70s:ATP (Caenorhabditis elegans)


name: SRD5A3 dehydrogenates TEST to DHTEST (Sus scrofa)


name: dehypoxanthine futalosine + S-adenosyl-L-methionine => 5'-deoxyadenosine + cyclic dehypoxanthinylfutalosinate + H(+) + L-methionine


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Danio rerio)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylated KHDRBS1 translocates to the cytosol (Drosophila melanogaster)


name: acetaldehyde + H2O + NAD(+) => acetate + 2 H(+) + NADH


name: (3R)-hydroxyoctadecanoyl-[ACP] = (2E)-octadecenoyl-[ACP] + H2O


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Homo sapiens)


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Schizosaccharomyces pombe)


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Bos taurus)


name: 2xTNFR2 binds TNFA trimer:TNFR2 (Bos taurus)


name: PPM1A dephosphorylates nuclear SMAD2/3 (Canis familiaris)


name: cyclohexane-1-carbonyl-CoA + NADP(+) = cyclohex-1-ene-1-carbonyl-CoA + H(+) + NADPH


name: 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine => [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: Vamp8 associated secretory vesicle to plasma membrane transport (Drosophila melanogaster)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Sus scrofa)


name: SMAC binds XIAP:Caspase-7 (Gallus gallus)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Homo sapiens)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Bos taurus)


name: SFN dimer binds CDK1 and CCNB1 (Bos taurus)


name: Dissociation of  transcript with 5'-GMP from GT (Danio rerio)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Rattus norvegicus)


name: p-Y-STATs translocate to nucleus (Mus musculus)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+) => 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline


name: TRIM27 polyubiquitinates PTEN (Sus scrofa)


name: FAS-mediated dimerization of procaspase-8 (Rattus norvegicus)


name: 3 AH2 + 2 H(+) + heme b + 3 O2 = 3 A + Fe(2+) + 3 H2O + mycobilin a


name: TRAPPC complexes exchange GTP for GDP on RAB1 (Dictyostelium discoideum)


name: GM-CSF receptor alpha:GM-CSF binds Bc (Canis familiaris)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate


name: "unsaturated chondroitin disaccharide hydrolase"


name: SUMOylation of NFKBIA with SUMO1 (Bos taurus)


name: RNA polymerase II cis-regulatory region sequence-specific DNA binding


name: IDUA hydrolyses Heparan sulfate chain(6) (Dictyostelium discoideum)


name: 1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + beta-D-galactosyl-(1<->1)-sphing-4-enine => 6-O-sulfo-beta-D-galactosyl-(1<->1)-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Bos taurus)


name: GDNF from the metanephric mesenchyme binds RET:GFRA1 on the nephric duct (Homo sapiens)


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Mus musculus)


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Bos taurus)


name: BCKDH transfers CoA group from CoA-SH to BCAAs (Plasmodium falciparum)


name: p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Rattus norvegicus)


name: 3-(3-hydroxyphenyl)-propanoyl-CoA + 3 H(+) + 3 malonyl-CoA => 3,3',5-trihydroxybibenzyl + 4 CO2 + 4 CoA


name: Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)


name: MADCAM1-1 binds Integrin alpha4beta7 (Homo sapiens)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Homo sapiens)


name: AXIN is phosphorylated in the destruction complex (Rattus norvegicus)


name: (R)-glycerate + NADP(+) = 3-hydroxypyruvate + H(+) + NADPH


name: XK:KEL:Zn2+ cleaves EDN3 (Rattus norvegicus)


name: ent-kaur-16-en-19-oate + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => gibberellin A12 + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA (Bos taurus)


name: L-leucine(out) + S-methylmercury-L-cysteine(in) = L-leucine(in) + S-methylmercury-L-cysteine(out)


name: (E)-feruloyl-CoA + H(+) + NADPH => (E)-coniferaldehyde + CoA + NADP(+)


name: CDC42 GDIs block activation of CDC42 (Sus scrofa)


name: 1D-myo-inositol 1,4,5-trisphosphate + H2O <=> 1D-myo-inositol 1,4-bisphosphate + phosphate


name: a ribonucleotide in RNA + S-adenosyl-L-methionine <=> a 2'-O-methylribonucleotide in RNA + H(+) + S-adenosyl-L-homocysteine


name: AcK-NFE2L2 binds the ATF4 gene (Homo sapiens)


name: 2-N-acetamidomethylphosphonate + CoA => acetyl-CoA + aminomethylphosphonate


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Canis familiaris)


name: NT5C2 tetramer phosphorylates RBV (Dictyostelium discoideum)


name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Homo sapiens)


name: tRNA-specific adenosine deaminase activity


name: NAD-dependent histone H4K16 deacetylase activity


name: N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity


name: 3'-phosphoadenylyl sulfate + cortisol <=> adenosine 3',5'-bisphosphate + cortisol 21-sulfate + H(+)


name: ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Homo sapiens)


name: 3,5,3'-triiodothyropyruvate + L-glutamate => 2-oxoglutarate + 3,3',5-triiodo-L-thyronine


name: EPHB:NMDAR binds TIAM1 (Canis familiaris)


name: ATP Hydrolysis By Myosin (Gallus gallus)


name: Activated protein C cleaves factor Va to factor Vi intermediate form (Danio rerio)


name: 4,5-dihydroxyphthalate + H(+) <=> 3,4-dihydroxybenzoate + CO2


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Canis familiaris)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Rattus norvegicus)


name: ABL1 phosphorylates RAD52 (Canis familiaris)


name: (5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+)


name: Binding of RRN3 to RNA Polymerase I (Dictyostelium discoideum)


name: 3-oxalomalate = glyoxylate + oxaloacetate


name: NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Xenopus tropicalis)


name: RHOA:GTP translocates to the ER membrane (Sus scrofa)


name: LONP1 binds mitochondrial inner membrane proteins (Saccharomyces cerevisiae)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Xenopus tropicalis)


name: holothin + marinoloyl-CoA C => CoA + thiomarinol C


name: a 7-hydroxyisoflavone + UDP-alpha-D-glucose => a 7-hydroxyisoflavone 7-O-beta-D-glucoside + H(+) + UDP


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Drosophila melanogaster)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Dictyostelium discoideum)


name: (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA + NAD(+) => 3,22-dioxochol-4-en-24-oyl-CoA + H(+) + NADH


name: alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP + H(+) => alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Canis familiaris)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Xenopus tropicalis)


name: ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Sus scrofa)


name: demethylsuberosin + O2 + reduced [NADPH--hemoprotein reductase] <=> (7S)-marmesin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)


name: 2-hydroxymelatonin + CO2 + succinate => 2-oxoglutarate + melatonin + O2


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Schizosaccharomyces pombe)


name: histone H3K4 dimethyltransferase activity


name: (2S)-heptan-2-amine + H2O + NAD(+) <=> H(+) + heptan-2-one + NADH + NH4(+)


name: a cytidine(6-4)cytidine in DNA <=> a cytidine dimer in DNA + H(+)


name: a tRNA + an N-acyl-L-amino acid + H(+) => an N-acyl-L-alpha-aminoacyl-tRNA + H2O


name: (R)-piperazine-2-carboxylate + NH4(+) => (R)-piperazine-2-carboxamide + H2O


name: 6-(alpha-D-glucosaminyl)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphate + H(+) => an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O


name: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O => scyllo-inosose


name: NGF homodimer binds to p75NTR (Sus scrofa)


name: Rsu-1 interacts with Pinch1 (Homo sapiens)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Dictyostelium discoideum)


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: miR-93 microRNA binds PTEN mRNA (Homo sapiens)


name: (2S,3S)-2-methylcitrate <=> 2-methyl-trans-aconitate + H2O


name: I-Smad competes with Co-Smad for R-Smad1/5/8 (Rattus norvegicus)


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + ATP + CoA <=> 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-CoA + AMP + diphosphate


name: PP2A dephosphorylates RAF1 (Rattus norvegicus)


name: Fe-coproporphyrin III + 2 H(+) + 2 H2O2 <=> 2 CO2 + 4 H2O + heme b


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Mus musculus)


name: Internalisation of the insulin receptor (Mus musculus)


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Rattus norvegicus)


name: RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils (Homo sapiens)


name: TRIKA2 binds K63polyUb-TRAF6 oligomer (Homo sapiens)


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)


name: maltose + H2O => 2 D-glucose (sucrase-isomaltase) (Homo sapiens)


name: Digestion of branched starch (amylopectin) by extracellular amylase (Xenopus tropicalis)


name: G protein-coupled glucose receptor activity


name: allocholoyl-CoA + deoxycholate => allocholate + deoxycholoyl-CoA


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O <=> 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: 15alpha-stemmadenine intermediate II + H2O => (16S)-deshydroxymethyl-stemmadenine + formate


name: CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH => CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NADP(+)


name: 2-deoxy-alpha-D-ribose 1-phosphate => 2-deoxy-D-ribose 5-phosphate


name: 1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA => 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA


name: Kinesin-5 is a homotetramer (Plasmodium falciparum)


name: SLC6A6-mediated uptake of taurine and beta-alanine (Plasmodium falciparum)


name: cis-4-hydroxy-L-proline + NAD(+) = 4-oxo-L-proline + H(+) + NADH


name: 3-oxooctanedioyl-CoA + CoA = acetyl-CoA + hexanedioyl-CoA


name: TBC1D7 binds the TSC1-TSC2 complex (Xenopus tropicalis)


name: CO2 + excited coelenteramide h monoanion + H(+) + hnu => coelenterazine h + O2


name: RHOQ GAPs stimulate RHOQ GTPase activity (Xenopus tropicalis)


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Danio rerio)


name: 4-hydroxyphenylacetonitrile + H2O => (Z)-(4-hydroxyphenyl)acetaldehyde oxime


name: RHOJ GAPs stimulate RHOJ GTPase activity (Canis familiaris)


name: MAP2K6 phosphorylates PIP4K2B (Xenopus tropicalis)


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Sus scrofa)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Dictyostelium discoideum)


name: SARS-CoV-1 SUMO-p-N binds to NPM1 (Homo sapiens)


name: 3-(hydrohydroxyphosphoryl)pyruvate + acetyl-CoA + H2O => CoA + H(+) + phosphinomethylmalate


name: diphosphate + dUMP + NH4(+) => dCTP + 2 H2O


name: NDUF subunits bind to form the IP subcomplex (Caenorhabditis elegans)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Caenorhabditis elegans)


name: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Drosophila melanogaster)


name: Basigin binds Mannose-carrying cell recognition molecules (Caenorhabditis elegans)


name: 4beta-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 4beta,24S-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Rattus norvegicus)


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Sus scrofa)


name: ZNRF3 autoubiquitinates to promote its internalization (Danio rerio)


name: pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Mus musculus)


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Sus scrofa)


name: 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine => guanosine(18) in tRNA + S-adenosyl-L-methionine


name: D-xylulose 5-phosphate + sulfoacetaldehyde => 4-deoxy-4-sulfo-D-erythrulose + D-glyceraldehyde 3-phosphate


name: 6-phospho-D-gluconate + NADP(+) <=> 6-phospho-2-dehydro-D-gluconate + H(+) + NADPH


name: 5-hydroxyxanthotoxin + S-adenosyl-L-methionine <=> isopimpinellin + S-adenosyl-L-homocysteine


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Rattus norvegicus)


name: CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Xenopus tropicalis)


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: (+)-7-isojasmonate + ATP + L-isoleucine = AMP + diphosphate + H(+) + L-isoleucine-(+)-7-isojasmonate


name: Vamp8 associated secretory vesicle to plasma membrane transport (Xenopus tropicalis)


name: P2Y11 receptor can bind to ATP (Bos taurus)


name: [aequorin]--dioxetanone <=> [excited state blue fluorescent protein] + CO2


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Rattus norvegicus)


name: 2 H(+) + precorrin-8X + S-adenosyl-L-homocysteine => precorrin-7 + S-adenosyl-L-methionine


name: citrate(out) + maleate(in) => citrate(in) + maleate(out)


name: holo-[ACP] + tetradecanoyl-AMP => AMP + H(+) + tetradecanoyl-[ACP]


name: H2O + L-threonyl-tRNA(Lys) => L-threonine + tRNA(Lys)


name: CO2(out) + H(+)(out) + ubiquinol-8 => formate(out) + 2 H(+)(in) + ubiquinone-8


name: H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2


name: Collagen type VII degradation by MMP1,2,3 (Caenorhabditis elegans)


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Xenopus tropicalis)


name: 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADPH => 2-deoxy-scyllo-inosamine + NADP(+)


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Caenorhabditis elegans)


name: EDNRA, EDNRB bind non-selective ERAs (Rattus norvegicus)


name: a CMP-N-acyl-beta-neuraminate + H2O <=> an N-acylneuraminate + CMP + H(+)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl thiocyanate + sulfate


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Canis familiaris)


name: H(+) + sitosteryl 3-beta-D-glucoside + UDP => sitosterol + UDP-alpha-D-glucose


name: amicoumacin A + ATP <=> ADP + amicoumacin A 2-phosphate + H(+)


name: (6S)-5,6,7,8-tetrahydrofolate + N,N-dimethylglycine + O2 = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O2 + sarcosine


name: (20S)-hydroxypregn-4-en-3-one + NADP(+) <=> H(+) + NADPH + progesterone


name: PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser (Rattus norvegicus)


name: 2 H2O + 2 leukotriene A4 + O2 => 2 lipoxin A4


name: WLS binds WNT ligands in the Golgi (Xenopus tropicalis)


name: 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) <=> (+)-costunolide + H2O


name: Thrombin-activated PARs activate G12/13 (Homo sapiens)


name: SLCO2B1 has a narrow substrate specificity (Canis familiaris)


name: 4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SESN1,2,3 bind overoxidized PRDX1 (Bos taurus)


name: L-leucine(in) + Na(+)(in) = L-leucine(out) + Na(+)(out)


name: hydrogen sulfide + O-acetyl-L-homoserine <=> acetate + L-homocysteine


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Sus scrofa)


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Canis familiaris)


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Sus scrofa)


name: all-trans-octaprenyl diphosphate + 5 diphosphate => (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate


name: Heterodimerization of CEACAMs (Xenopus tropicalis)


name: chloride(in) + hypotaurine(in) + 2 Na(+)(in) => chloride(out) + hypotaurine(out) + 2 Na(+)(out)


name: (1S,5R)-carveol + NAD(+) => (R)-carvone + H(+) + NADH


name: glyoxal + GMP = N(2)-(1-hydroxy-2-oxoethyl)-GMP


name: a quinol + dihydroxyacetone phosphate => a quinone + sn-glycerol 3-phosphate


name: L-homoserine <=> 2-oxobutanoate + NH4(+)


name: (9Z,12Z)-octadecadienoate + O2 => (13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: HGSNAT oligomer acetylates Heparan chain(1) (Homo sapiens)


name: Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG (Gallus gallus)


name: CECRI deaminates Ade-Rib to Ino (Homo sapiens)


name: ULK1 phosphorylates RIPK1 at S357 (Homo sapiens)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Sus scrofa)


name: H2O + 2 O2 + thiamine = H(+) + 2 H2O2 + thiamine acetate


name: SDC2 multimerises (Drosophila melanogaster)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Homo sapiens)


name: 4-hydroxy-N,N,N-trimethyltryptamine + ATP => ADP + aeruginascin + H(+)


name: REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides (Homo sapiens)


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA => (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O


name: mechanosensitive voltage-gated sodium channel activity


name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Mus musculus)


name: 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA (Homo sapiens)


name: a fatty acyl-CoA + sphinga-4E,14Z-dienine => an N-acyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: H2O + prostaglandin D2-1-glycerol ester <=> glycerol + H(+) + prostaglandin D2


name: H2O + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine = a fatty acid + H(+) + N,1-diacyl-sn-glycero-3-phosphoethanolamine


name: 6-sulfo-D-quinovose + FMNH2 + O2 = 6-dehydro-D-glucose + FMN + 2 H(+) + H2O + sulfite


name: H(+)(in) + shikimate(in) = H(+)(out) + shikimate(out)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+) => 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-choline


name: 4-(hydroxyamino)quinoline N-oxide + H2O + 2 NADP(+) = 4-nitroquinoline N-oxide + 2 H(+) + 2 NADPH


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Sus scrofa)


name: (S)-2-amino-6-oxohexanoyl-[protein] + acetamide + H2O2 => H2O + N(6)-acetyl-L-lysyl-[protein] + O2


name: FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer (Homo sapiens)


name: Cathepsin G proteolyzes IGF:IGFBP3:ALS (Rattus norvegicus)


name: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate <=> 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine


name: LTC4 is exported from the cytosol by ABCC1 (Sus scrofa)


name: SLC17A3-2 transports cytosolic urate to extracellular region (Caenorhabditis elegans)


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Gallus gallus)


name: HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane (Sus scrofa)


name: D-sedoheptulose 7-phosphate => (R)-demethyl-4-deoxygadusol + H(+) + H2O + phosphate


name: 2 H(+) + H2O + thiocyanate => carbonyl sulfide + NH4(+)


name: (2Z,6E)-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphate


name: Interaction of Nectins with Afadin (Bos taurus)


name: (2E)-geranyl diphosphate => (1R,5R)-sabinene + diphosphate


name: S-adenosyl-L-methionine + xanthosine => 7-methylxanthosine + S-adenosyl-L-homocysteine


name: Recruitment of  RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Mus musculus)


name: Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)


name: GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity


name: Resumption of elongation after recovery from pausing (Drosophila melanogaster)


name: NOTCH1 PEST domain mutants bind DLL4 (Homo sapiens)


name: Formation of ORC(2-5) complex (Gallus gallus)


name: NOTCH3 coactivator complex binds HES1 gene promoter (Homo sapiens)


name: Removal of miRNA passenger strand (Sus scrofa)


name: alpha-tubulin:GTP:Cofactor B  +Cofactor E ->  alpha-tubulin:GTP: Cofactor E +Cofactor B (Homo sapiens)


name: USP17 deubiquitinates SUDS3 (Drosophila melanogaster)


name: L-arginyl-[protein] + L-cysteinyl-[protein] + methylglyoxal => H(+) + 2 H2O + N(5)-[4-(S-L-cysteinyl-[protein])-5-methyl-1H-imidazol-2-yl]-L-ornithinyl-[protein]


name: 4-coumaroyl-CoA + H(+) + malonyl-CoA <=> (4-coumaroyl)acetyl-CoA + CO2 + CoA


name: 2 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone => 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Danio rerio)


name: all-trans-zeaxanthin + 2 O2 <=> 2 3beta-hydroxy-beta-cyclocitral + crocetin dialdehyde


name: 2,3-dihydroxybenzoate + H(+) = catechol + CO2


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Homo sapiens)


name: 5'-deoxyadenosine + A + dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + H(+) + L-methionine + NH4(+) => AH2 + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + S-adenosyl-L-methionine


name: sGC stimulators bind sGC:NO (Drosophila melanogaster)


name: ADP-D-ribose + H2O => AMP + D-ribose 5-phosphate + 2 H(+)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Rattus norvegicus)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Caenorhabditis elegans)


name: AH2 + chermesin D methyl ester <=> A + asnovolin J


name: ANO1 transports cytosolic Cl- to extracellular region (Canis familiaris)


name: O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin B <=> 6-hydroxytryprostatin B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADD1:ADD2 binds DMTN (Rattus norvegicus)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)


name: D-glyceraldehyde 3-phosphate + NAD(+) + phosphate => (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH


name: a globoside Gb3Cer (d18:1(4E)) + UDP-alpha-D-galactose = a globoside GalGb3Cer (d18:1(4E)) + H(+) + UDP


name: Fe3+ dissociates from holoTF:TFRC dimer (Gallus gallus)


name: (2E,6E,10E)-geranylgeranyl diphosphate = diphosphate + isoelisabethatriene


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Xenopus tropicalis)


name: WNTs are secreted in exosomes (Bos taurus)


name: apelin-16 + L-phenylalanine => apelin-17 + H2O


name: Dehydratation of DHQ yields DHS (Mycobacterium tuberculosis)


name: H2O + L,L-cystathionine <=> L-homocysteine + NH4(+) + pyruvate


name: a 3beta-hydroxy-4,4-dimethylsteroid + H(+) + NADH + O2 => a 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + H2O + NAD(+)


name: cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-cholest-5-ene-3beta,26-diol + H2O + 2 oxidized [adrenodoxin]


name: FABP5 dissociates from RXRA:PPARD:atRA (Caenorhabditis elegans)


name: SORD oxidizes D-sorbitol to Fru (Saccharomyces cerevisiae)


name: ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Drosophila melanogaster)


name: D-mannose(out) + Na(+)(out) = D-mannose(in) + Na(+)(in)


name: Translocation of NFATC1:CaN:CaM to nucleus (Gallus gallus)


name: Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Bos taurus)


name: 2-oxoglutarate + chloride + H(+) + hapalindole U + O2 => CO2 + H2O + hapalindole G + succinate


name: 7-aminomethyl-7-carbaguanine + 2 NADP(+) <=> 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH


name: SRC-1 phosphorylates SHB (Canis familiaris)


name: RAS GEFs promote RAS nucleotide exchange (Danio rerio)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Xenopus tropicalis)


name: Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Bos taurus)


name: [(1->4)-alpha-D-glucosyl](n) + sucrose => [(1->4)-alpha-D-glucosyl](n+1) + D-fructose


name: H2O + N(6)-methyl-dATP => diphosphate + H(+) + N(6)-methyl-dAMP


name: 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O <=> 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Homo sapiens)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA => 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Plasmodium falciparum)


name: (+)-thujan-3-one + H(+) + NADH => (+)-thujan-3-ol + NAD(+)


name: ATP + folate(in) + H2O => ADP + folate(out) + H(+) + phosphate


name: a 2'-deoxyribonucleoside 5'-diphosphate + H2O <=> a 2'-deoxyribonucleoside 5'-phosphate + H(+) + phosphate


name: snRNP nuclear import and release (Homo sapiens)


name: D-galactose(in) + H(+)(in) = D-galactose(out) + H(+)(out)


name: ergosteryl 3-beta-D-glucoside + H2O => D-glucose + ergosterol


name: O2 + octanoyl-CoA <=> (2E)-octenoyl-CoA + H2O2


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Canis familiaris)


name: 2-oxobutanoate + L-cysteine <=> (2S)-2-aminobutanoate + 2-oxo-3-sulfanylpropanoate


name: ATP + H2O + phosphinate(out) = ADP + H(+) + phosphate + phosphinate(in)


name: (2E,6E)-farnesyl diphosphate = (1R,4R,5S)-(-)-guaia-6,10(14)-diene + diphosphate


name: ST3GAL5 transfers NeuNAc to ceramides (Homo sapiens)


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Danio rerio)


name: 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Caenorhabditis elegans)


name: 2,4-dichlorophenol + CO2 + pyruvate + succinate => (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2


name: L-arginine + L-cysteinyl-[NO transferase protein] + NADPH + 2 O2 => 2 H2O + L-citrulline + NADP(+) + S-nitroso-L-cysteinyl-[NO transferase protein]


name: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) <=> ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate


name: 3'-phosphoadenylyl sulfate + a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol => 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+)


name: TRPs transport extracellular Ca2+ to cytosol (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(9Z-octadecenoyl) ethanolamine => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-[(9Z)-octadecenoylamino]ethyl (9Z)-octadecenoate


name: dimethylallyl diphosphate + 2 isopentenyl diphosphate => (2Z,6Z)-farnesyl diphosphate + 2 diphosphate


name: 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + ribostamycin => gamma-L-glutamyl-butirosin B + H(+) + holo-[BtrI ACP]


name: (R)-4'-phosphopantetheine + H2O => (R)-pantetheine + phosphate


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Sus scrofa)


name: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O => 1D-myo-inositol 1,4,5-trisphosphate + phosphate


name: 3-oxooctanedioyl-CoA + H(+) + NADH => (3S)-hydroxyoctanedioyl-CoA + NAD(+)


name: 11-cis-retinol + NADP(+) <=> 11-cis-retinal + H(+) + NADPH


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Bos taurus)


name: STAT1,STAT3 binds PKR (Canis familiaris)


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Sus scrofa)


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Danio rerio)


name: (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2


name: acetate-CoA ligase (ADP-forming) activity


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + a ribonucleoside 5'-triphosphate <=> a 5'-end NTP-ribonucleotide-RNA + AMP + H(+)


name: HSD17B1 hydrogenates E1 to EST17b (Bos taurus)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Canis familiaris)


name: A + a 2,3-saturated acyl-CoA => a 2,3-dehydroacyl-CoA + AH2


name: PVR:PVRL3 trans heterodimer interaction (Mus musculus)


name: TULP3 is required for GPR161 localization in the cilium (Mus musculus)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Bos taurus)


name: MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Mus musculus)


name: EP300 acetylates histone H2A, H2B, H3, H4 (Drosophila melanogaster)


name: UCHL1, UCHL3 cleave ubiquitin adducts (Rattus norvegicus)


name: (3R)-hydroxy-(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA <=> (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + H2O


name: A + decanedioyl-CoA = (2E)-decenedioyl-CoA + AH2


name: diphosphate + lydicene => (2E,6E,10E)-geranylgeranyl diphosphate


name: 2 CoA + NADP(+) <=> CoA-disulfide + H(+) + NADPH


name: RHOA binds effectors at the plasma membrane (Gallus gallus)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Caenorhabditis elegans)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Saccharomyces cerevisiae)


name: a ganglioside GM1b + H2O => a ganglioside GA1 + N-acetylneuraminate


name: Addition of galactose to Core 6 glycoprotein (Sus scrofa)


name: 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA = 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: cyanurate + H2O = 1-carboxybiuret + H(+)


name: 9beta-pimara-7,15-dien-19-al + O2 + reduced [NADPH--hemoprotein reductase] <=> 9beta-pimara-7,15-dien-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Association of Cyclin A:Cdk2 with Cdh1 (Drosophila melanogaster)


name: a ganglioside GA1 (d18:1(4E)) + H(+) + UDP => a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose


name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) (Bos taurus)


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Xenopus tropicalis)


name: (R)-3-hydroxybutanoate + NAD(+) <=> acetoacetate + H(+) + NADH


name: D-ribose + H(+) + nicotinamide => beta-nicotinamide D-riboside + H2O


name: (R)-noradrenaline(out) + chloride(out) + Na(+)(out) <=> (R)-noradrenaline(in) + chloride(in) + Na(+)(in)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Caenorhabditis elegans)


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Danio rerio)


name: a sphingoid base + hexadecanoyl-CoA = an N-hexadecanoyl-sphingoid base + CoA + H(+)


name: Dopachrome is transformed to DHICA by DCT (Homo sapiens)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Dictyostelium discoideum)


name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Homo sapiens)


name: Collagen type XIII binds Integrin alpha1beta1 (Sus scrofa)


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Drosophila melanogaster)


name: NOX4, NOX5 reduce O2 to O2.- (Gallus gallus)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADH + O2 => 4beta-hydroxymethyl-4alpha-methylzymosterol + H2O + NAD(+)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)


name: H2O + sphinganine 1-phosphate <=> phosphate + sphinganine


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Homo sapiens)


name: B4GALTs transfer Gal to a branch of keratan (Drosophila melanogaster)


name: a medium-chain (3S)-3-hydroxyacyl-CoA = a medium-chain (2E)-enoyl-CoA + H2O


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Mus musculus)


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O => 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: galactitol + NAD(+) <=> H(+) + keto-L-tagatose + NADH


name: arbutin 6-phosphate + H2O => beta-D-glucose 6-phosphate + hydroquinone


name: 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Saccharomyces cerevisiae)


name: H(+)(in) + oxaloacetate(out) + phosphate(in) <=> H(+)(out) + oxaloacetate(in) + phosphate(out)


name: Formation of COPII vesicle (Rattus norvegicus)


name: Caspase-9 binds DCC:DIP13alpha complex (Rattus norvegicus)