name: Elongation of pre-rRNA transcript (Schizosaccharomyces pombe)


name: a thymidine in DNA + S-methyl-L-cysteinyl-[protein] => a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein]


name: (Frs2)Rap1-GTP binds to and activates B-Raf (Homo sapiens)


name: SIRPA binds SFTPA oligomer, SFTPD oligomer (Mus musculus)


name: (R)-linalool + diphosphate => (2E)-geranyl diphosphate + H2O


name: H2O + malonaldehyde + O2 => 3-oxopropanoate + H(+) + H2O2


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP(+) <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + H(+) + NADPH


name: 3-oxochol-4-en-22-oyl-CoA + H(+) + NADH + O2 <=> 9alpha-hydroxy-3-oxochol-4-en-22-oyl-CoA + H2O + NAD(+)


name: alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+) => alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate


name: 6-hydroxyhexan-6-olide + H2O + NADP(+) => 2-hydroxycyclohexan-1-one + H(+) + NADPH + O2


name: (Z)-(4-hydroxyphenyl)acetaldehyde oxime => (E)-4-hydroxyphenylacetaldehyde oxime


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + hexadecanoyl-CoA + O2 = (6Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Bos taurus)


name: Active p38 MAPK phosphorylates MAPKAPK5 (Gallus gallus)


name: HGSNAT oligomer acetylates Heparan chain(1) (Bos taurus)


name: Further sulfation on galactose residues produces KSPG (Canis familiaris)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Bos taurus)


name: RFC binding displaces Pol Alpha on the C-strand of the telomere (Canis familiaris)


name: MAOB:FAD oxidatively deaminates of PEA (Rattus norvegicus)


name: TOPORS SUMOylates IKBKE with SUMO1 (Xenopus tropicalis)


name: "With NADH or NADPH as one donor, and the other dehydrogenated"


name: Fusion of early-endosome derived vesicles at the TGN (Drosophila melanogaster)


name: a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: EPHA binds TIAM1 (Drosophila melanogaster)


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Canis familiaris)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Caenorhabditis elegans)


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Danio rerio)


name: Glucagon binds to Glucagon receptor (Rattus norvegicus)


name: D-ribulose 1,5-bisphosphate + O2 = (2R)-3-phosphoglycerate + 2-phosphoglycolate + 2 H(+)


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Saccharomyces cerevisiae)


name: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine => H(+) + N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine


name: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate <=> all-trans-hexaprenyl diphosphate + 3 diphosphate


name: H(+) + malonate + Na(+)(in) <=> acetate + CO2 + Na(+)(out)


name: a guanosine in RNA + methylglyoxal <=> an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Danio rerio)


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Saccharomyces cerevisiae)


name: NPAS4 binds CDK5R1 gene promoter (Homo sapiens)


name: Formation of ERCC1:XPF heterodimeric complex (Danio rerio)


name: 3'-phosphoadenylyl sulfate + beta-D-Gal-(1<->1')-Cer <=> 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Rattus norvegicus)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Caenorhabditis elegans)


name: IL21:IL21R:JAK1 binds IL2RG:JAK3 (Homo sapiens)


name: [DsbA protein]-dithiol + [DsbB protein]-disulfide = [DsbA protein]-disulfide + [DsbB protein]-dithiol


name: chloride(out) + L-serine(out) + 2 Na(+)(out) => chloride(in) + L-serine(in) + 2 Na(+)(in)


name: Association of procollagen type XXV (Bos taurus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+) => 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O


name: Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Canis familiaris)


name: beta-maaliene + diphosphate => (2E,6E)-farnesyl diphosphate


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Dictyostelium discoideum)


name: arachidonic acid 11,12-epoxygenase activity


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GBF1 stimulates ARF nucleotide exchange (Sus scrofa)


name: dodecanoyl-[ACP] + H(+) + malonyl-[ACP] => 3-oxotetradecanoyl-[ACP] + CO2 + holo-[ACP]


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Bos taurus)


name: WLS is endocytosed to the early endosome (Homo sapiens)


name: acetyl-CoA + fumigaclavine B = CoA + fumigaclavine A


name: Binding of TFIIE to the growing preinitiation complex (Gallus gallus)


name: (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 = (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate


name: D-glucuronate + H(+) + mycophenolate => H2O + mycophenolic acid O-acyl-beta-D-glucuronide


name: (3R)-hydroxydodecanoyl-[ACP] + NADP(+) => 3-oxododecanoyl-[ACP] + H(+) + NADPH


name: (2,5-ethylene furandicarboxylate)(n) + 2 H2O = (2,5-ethylene furandicarboxylate)(n-1) + 2,5-dicarboxyfuran + ethylene glycol + 2 H(+)


name: RRAGA,B exchanges GDP for GTP (Homo sapiens)


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Rattus norvegicus)


name: a 1-acyl-sn-glycerol + an acyl-CoA => a 1,3-diacyl-sn-glycerol + CoA


name: butan-1-ol + NAD(+) = butanal + H(+) + NADH


name: glyoxylate + L-tryptophan <=> glycine + indole-3-pyruvate


name: ADP + beta-D-glucosylceramide(out) + H(+) + phosphate => ATP + beta-D-glucosylceramide(in) + H2O


name: serotonin-gated monoatomic cation channel activity


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + hexadecanoate


name: "[ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase"


name: 3-formylthiophene + hydrogen cyanide <=> (2S)-2-hydroxy-2-(thiophen-3-yl)acetonitrile


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Xenopus tropicalis)


name: 2-oxobutanoate + CO2 => 3-carboxy-2-oxobutanoate + H(+)


name: Constitutive phosphorylation by GSK3 (Bos taurus)


name: CYP11B2 oxidises 18HCORST to ALDO (Homo sapiens)


name: HRH2 binds hist (Drosophila melanogaster)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Sus scrofa)


name: [thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]


name: 2 isomaltose => alpha-isomaltosyl-(1->3)-isomaltose + H2O


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Canis familiaris)


name: a plastoquinone + (n+1) H(+)(in) + NADPH <=> a plastoquinol + n H(+)(out) + NADP(+)


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Drosophila melanogaster)


name: histone H4K20 trimethyltransferase activity


name: ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]


name: 14-3-3 proteins bind AKT-phosphorylated FOXO4 (Caenorhabditis elegans)


name: Oxidation of cholesterol to 22beta-hydroxycholesterol (Mus musculus)


name: 5,6-dihydrouridine(17) in tRNA + NADP(+) <=> H(+) + NADPH + uridine(17) in tRNA


name: SUMOylation of NPM1 with SUMO2,3 (Homo sapiens)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Xenopus tropicalis)


name: (R)-carnitine + decanoyl-CoA = CoA + O-decanoyl-(R)-carnitine


name: alpha-D-galactosyl-(1->3)-1D-myo-inositol + raffinose <=> myo-inositol + stachyose


name: 4-acetamidobutanoate + H2O <=> 4-aminobutanoate + acetate


name: a 1-acyl-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2 => a 1-acyl-2-(15-hydroperoxy-8Z,11Z,13E-eicosatrienoyl)-sn-glycero-3-phospho-(1D-myo-inositol)


name: botE HC:LC binds SV2A or B and GT1b on the target cell surface (Homo sapiens)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Caenorhabditis elegans)


name: Autocatalytic phosphorylation of FGFR1b (Drosophila melanogaster)


name: CO2 + H2O + kainate + succinate => 2-oxoglutarate + O2 + prekainate


name: gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)


name: (3S)-3-hydroxy-L-lysine + CO2 + succinate => 2-oxoglutarate + L-lysine + O2


name: H(+) + NAD(+) + 2 reduced [2Fe-2S]-[putidaredoxin] <=> NADH + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: p130Cas and C3G bind PDGFR bound Crk (Drosophila melanogaster)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Sus scrofa)


name: 6'''-deamino-6'''-oxoneomycin C + L-glutamate => 2-oxoglutarate + neomycin C


name: palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Xenopus tropicalis)


name: alpha-D-glucose 1-phosphate + D-glucose => beta-D-glucosyl-(1->3)-D-glucose + phosphate


name: MTORC1 dissociates from ULK complex (Xenopus tropicalis)


name: PDE6D dissociates from ARL13B:INPP5E (Sus scrofa)


name: pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine


name: Tankyrase binds AXIN (Rattus norvegicus)


name: L-arginine(in) + L-methionine(out) + Na(+)(out) = L-arginine(out) + L-methionine(in) + Na(+)(in)


name: ADP + gamma-L-glutamyl-isopropylamide + H(+) + phosphate => ATP + isopropylamine + L-glutamate


name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate (Homo sapiens)


name: IRE1 dimer autophosphorylates (Xenopus tropicalis)


name: CoA + H(+) + S-(2-acetamidoethyl)-L-cysteine => acetyl-CoA + S-(2-aminoethyl)-L-cysteine


name: Assembly of the HCMV Genome DNA Replication Complex (Homo sapiens)


name: ATP + estrone 3-sulfate(out) + H2O => ADP + estrone 3-sulfate(in) + H(+) + phosphate


name: TRAIL-mediated dimerization of procaspase-8 (Mus musculus)


name: MUS81:EME1,EME2 cleaves D-loop (Sus scrofa)


name: H(+)(in) + myo-inositol(in) => H(+)(out) + myo-inositol(out)


name: Disassembly of tight junctions (Canis familiaris)


name: POLK incorporates dNMP opposite to damaged DNA base (Saccharomyces cerevisiae)


name: 2 H(+) + NADH + trimethylamine N-oxide => H2O + NAD(+) + trimethylamine


name: SLC6A3 binds DRIs (Drosophila melanogaster)


name: 15,9'-di-cis-phytofluene + plastoquinone-9 => 9,9',15-tri-cis-zeta-carotene + plastoquinol-9


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-(9Z-octadecaenoyl)-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Drosophila melanogaster)


name: Reduction of desmosterol to cholesterol (Danio rerio)


name: RHOU binds effectors at the plasma membrane (Canis familiaris)


name: cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine <=> H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine


name: ProSPZ:SPZ dimer binds to TL receptor at the plasma membrane (Drosophila melanogaster)


name: a globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a globoside Gb4Cer (d18:1(4E)) + H(+) + UDP


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Caenorhabditis elegans)


name: SUMOyation of DNMT1 with SUMO1 (Mus musculus)


name: D-mannitol 1-phosphate + NADP(+) <=> D-mannose 6-phosphate + H(+) + NADPH


name: Kinesin-13 is a dimer (Caenorhabditis elegans)


name: luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] + UDP-alpha-D-glucuronate <=> H(+) + luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] 4'-O-beta-D-glucuronide + UDP


name: (3E,6E)-alpha-farnesene + diphosphate => (2E,6E)-farnesyl diphosphate


name: p-CBL:GRB2 binds p-FRS2:activated FGFR2 (Drosophila melanogaster)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => H(+) + hexadecanoate + hexadecanoyl-glycero-3-phospho-(1D-myo-inositol)


name: 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Schizosaccharomyces pombe)


name: DUX4, TPRXL, TPRX1, TPRX2, EP300, and CREBBP bind the ZSCAN4 gene (Homo sapiens)


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) = (6S)-5-formyl-5,6,7,8-tetrahydrofolate(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Homo sapiens)


name: HTR1A binds HTR1A antagonists (Homo sapiens)


name: 3,4-dihydroxyphenylacetaldehyde + H2O + NAD(+) => 3,4-dihydroxyphenylacetate + 2 H(+) + NADH


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP


name: Polyubiquitinated NRIF binds to p62 (Sequestosome) (Rattus norvegicus)


name: AH2 + Latia luciferin + 2 O2 <=> A + CO2 + formate + H(+) + H2O + hnu + oxidized Latia luciferin


name: Aquaporins passively transport urea out of cells (Schizosaccharomyces pombe)


name: GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + H(+) + phosphate => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O


name: APC/C:Cdh1 polyubiquitinates SKP2 (Gallus gallus)


name: androst-4-ene-3,17-dione + H(+) + NADPH = 5alpha-androstan-3,17-dione + NADP(+)


name: a 2-acyl-sn-glycerol 3-phosphate + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phosphate + H2O


name: Release of the SLBP independent Histone mRNA from the NPC (Sus scrofa)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: beta-NGF dimer binds to TrkA receptor (Homo sapiens)


name: ERBB4s80:STAT5A complex translocates to the nucleus (Rattus norvegicus)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Drosophila melanogaster)


name: PLC-gamma1 hydrolyses PIP2 (Plasmodium falciparum)


name: FITM1, FITM2 bind TAGs (Schizosaccharomyces pombe)


name: (2E)-decenal + H(+) + NADPH => decanal + NADP(+)


name: enterobactin + H2O = N-(2,3-dihydroxybenzoyl)-L-serine trimer


name: malonate(in) + succinate(out) => malonate(out) + succinate(in)


name: (S)-sec-butylamine + H2O + NAD(+) <=> butan-2-one + H(+) + NADH + NH4(+)


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 18-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 (Canis familiaris)


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Homo sapiens)


name: Crk binds to the active PDGF receptor (Danio rerio)


name: choline(in) + n Na(+)(in) => choline(out) + n Na(+)(out)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Mus musculus)


name: 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Mus musculus)


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Bos taurus)


name: [(1->6)-alpha-D-glucosyl](n) + sucrose <=> [(1->6)-alpha-D-glucosyl](n+1) + D-fructose


name: SMURF2 monoubiquitinates SMAD3 (Homo sapiens)


name: an aldehyde + CO2 => a 2-oxocarboxylate + H(+)


name: 15-cis-4,4'-diapophytoene + 3 FAD + 3 H(+) <=> all-trans-4,4'-diaponeurosporene + 3 FADH2


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Xenopus tropicalis)


name: Homer1,2,3 binds mGluR1a,5 (Rattus norvegicus)


name: TP53 stimulates TIGAR expression (Homo sapiens)


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Mus musculus)


name: MLCL is acylated to CL by HADH (IM) (Caenorhabditis elegans)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Mus musculus)


name: KCNJs transport K+ from the extracellular region to cytosol (Canis familiaris)


name: 2 H(+) + 2 malonyl-CoA + octadecanoyl-CoA = 4-hydroxy-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA


name: RHOD translocates to the Golgi membrane (Gallus gallus)


name: MTMR12 binds MTMR2 (Dictyostelium discoideum)


name: CoA + O-tetradecanoyl-L-seryl-[protein] => L-seryl-[protein] + tetradecanoyl-CoA


name: 3'-phosphoadenylyl sulfate + a thiol <=> adenosine 3',5'-bisphosphate + H(+) + S-alkyl thiosulfate


name: 2-oxobutanoate + L-histidine = (2S)-2-aminobutanoate + 3-(imidazol-5-yl)pyruvate


name: ADRA2A,B,C bind ADR,NAd (Drosophila melanogaster)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)


name: (3S)-3-hydroxybutanoyl-CoA + H2O <=> (S)-3-hydroxybutanoate + CoA + H(+)


name: NICD2 binds RBPJ and MAML in the nucleus (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate = (-)-beta-santalene + diphosphate


name: Defective NTHL1 truncation mutants do not bind dihydrouracil (DHU) (Homo sapiens)


name: GNLY binds the bacterial cell surface in the phagosome (Canis familiaris)


name: PC catalyzes the carboxylation of PYR to form OA (Homo sapiens)


name: Edited Kainate Receptor binds glutamate (Bos taurus)


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Canis familiaris)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Rattus norvegicus)


name: H2O + N(5)-ethyl-L-glutamine <=> ethylamine + L-glutamate


name: (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 <=> (E)-2,4-dihydroxycinnamoyl-CoA + CO2 + succinate


name: Furin cleaves pro-protein C to protein C (Danio rerio)


name: Growth hormone binds the growth hormone receptor (Homo sapiens)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Bos taurus)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Translocation of PMAIP1 (NOXA) to mitochondria (Mus musculus)


name: 3-maleylpyruvate + H2O <=> H(+) + maleate + pyruvate


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Mus musculus)


name: all-trans-hexaprenyl diphosphate + 3 diphosphate => (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate


name: Thrombin-activated PARs:Gq (active) dissociate (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 = (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: ATXN3 family cleave Ub chains (Homo sapiens)


name: FABP5 dissociates from RXRA:PPARD:atRA (Bos taurus)


name: (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H(+) + NADPH = (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + NADP(+)


name: The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Mus musculus)


name: CYP3A4 can N-demethylate loperamide (Xenopus tropicalis)


name: 3-hydroxy-3-methylhexanoate + L-glutamine => H2O + N(2)-(3-hydroxy-3-methylhexanoyl)-L-glutaminate


name: (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate = 3-hydroxypropyl isothiocyanate + sulfate


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Rattus norvegicus)


name: P2X7 mediates loss of intracellular K+ (Rattus norvegicus)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H(+) + UDP


name: Some HSPGs are secreted to the plasma membrane (Danio rerio)


name: Binding of TFIIE to the growing preinitiation complex (Xenopus tropicalis)


name: eIF3 and eIF1A bind to the 40S subunit (Gallus gallus)


name: Translation of ROBO3.2 mRNA initiates NMD (Homo sapiens)


name: Activated FGFR1 binds FRS2 (Gallus gallus)


name: PP5 dephosphorylates RAF1 S338 (Bos taurus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Canis familiaris)


name: H(+) + L-xylono-1,4-lactone + NADPH => L-xylose + NADP(+)


name: The phagophore extends from the PIP3-enriched structure (Schizosaccharomyces pombe)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Bos taurus)


name: DAG is acylated to TAG by DGAT1/2 (Sus scrofa)


name: (indol-3-yl)acetate + succinyl-CoA = (indol-3-yl)acetyl-CoA + succinate


name: H(+)(out) + L-alanyl-L-leucyl-L-alanine(out) => H(+)(in) + L-alanyl-L-leucyl-L-alanine(in)


name: 4alpha-hydroxymethylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-formylzymosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: OPTN binds polyUb-RIPK1 within the TNFR1 complex (Rattus norvegicus)


name: an N-acetyl-L-cysteine-S-conjugate + H2O = acetate + an S-substituted L-cysteine


name: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2


name: RAS:GTP binds PI3K (Drosophila melanogaster)


name: (E)-sinapyl alcohol + O2 <=> (E)-sinapaldehyde + H2O2


name: Tyrosine is monoiodinated (Canis familiaris)


name: H2O + L-valine + NADP(+) => 3-methyl-2-oxobutanoate + H(+) + NADPH + NH4(+)


name: ATP + N-acetyl-D-muramate <=> ADP + H(+) + N-acetyl-alpha-D-muramate 1-phosphate


name: ATP + L-aspartate + tRNA(Asp) <=> AMP + diphosphate + L-aspartyl-tRNA(Asp)


name: Association of procollagen type XVI (Homo sapiens)


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)


name: DHAP is converted to 1-acyl GO3P by GNPAT (Canis familiaris)


name: 7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O <=> 7,8-dihydroneopterin 3'-phosphate + H(+)


name: Nectin-1:PVRL3 trans heterodimer formation (Rattus norvegicus)


name: demethylphylloquinol + S-adenosyl-L-methionine => H(+) + phylloquinol + S-adenosyl-L-homocysteine


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Bos taurus)


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Bos taurus)


name: a fatty acyl-CoA + sphinganine <=> an N-acylsphinganine + CoA + H(+)


name: Loaded mycobactin gets imported (Homo sapiens)


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Bos taurus)


name: D-xylose(in) + H(+)(in) <=> D-xylose(out) + H(+)(out)


name: L-tyrosyl-[protein] + NAD(+) <=> H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein]


name: 3-phenylpyruvate + L-tryptophan => indole-3-pyruvate + L-phenylalanine


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Bos taurus)


name: H(+) + menaquinol-10 + S-adenosyl-L-homocysteine => 2-demethylmenaquinol-10 + S-adenosyl-L-methionine


name: SAR1 Activation And Membrane Binding (Homo sapiens)


name: Acyl Ghrelin and C-Ghrelin are secreted (Rattus norvegicus)


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Drosophila melanogaster)


name: 2 adenosylcob(III)alamin + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate => 2 ATP + 2 cob(II)alamin + 2 H2O + reduced [electron-transfer flavoprotein]


name: OPN1LW binds 11cRAL (Caenorhabditis elegans)


name: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + UDP-alpha-D-glucuronate => an alpha-D-glucuronosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + H(+) + UDP


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)


name: A + all-trans-lycopene + dimethylallyl diphosphate + H2O <=> AH2 + diphosphate + nonaflavuxanthin


name: PTPN11 dephosphorylates RUNX1 (Homo sapiens)


name: p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus (Drosophila melanogaster)


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Bos taurus)


name: H(+) + holo-[ACP] + N(6)-(fatty acyl)-L-lysyl-[protein] => a fatty acyl-[ACP] + L-lysyl-[protein]


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Mus musculus)


name: Autophosphorylation of PDGF alpha/beta receptors (Canis familiaris)


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + succinate


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + Na(+)(in) <=> a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + Na(+)(out)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Bos taurus)


name: ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Canis familiaris)


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] = atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NFE2L2-dependent ME1 gene expression (Homo sapiens)


name: a 2-(omega-methylsulfanyl)alkylmalate <=> a 3-(omega-methylsulfanyl)alkylmalate


name: N(2)-(1-hydroxy-2-oxopropyl)-GDP => GDP + methylglyoxal


name: ALDH3A2-2 oxidizes pristanal to pristanate (Drosophila melanogaster)


name: 2-acyl LPE is acylated to PE by LPEAT (Saccharomyces cerevisiae)


name: DAG kinase produces phosphatidic acid from DAG (Caenorhabditis elegans)


name: Fall Back to Closed Pre-initiation Complex (Drosophila melanogaster)


name: L-asparagine <=> 3-cyano-L-alanine + H2O


name: SOX17 binds the PDPN gene (Homo sapiens)


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: neryl diphosphate + olivetolate <=> cannabinerolate + diphosphate


name: Aquaporin-6 passively transports anions out of vesicles (Homo sapiens)


name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] (Gallus gallus)


name: H(+) + H2O + L-tyrosine + O2 <=> (4-hydroxyphenyl)acetaldehyde + CO2 + H2O2 + NH4(+)


name: 2-methoxy-6-(all-trans-hexaprenyl)phenol + H(+) + NADPH + O2 = 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + H2O + NADP(+)


name: VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Xenopus tropicalis)


name: (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + H(+) + NADH => (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-2,6-dimethyloct-6-enoyl-CoA + NAD(+)


name: 2 bilirubin IXalpha + O2 = 2 biliverdin IXalpha + 2 H2O


name: CRH gene expression is repressed by MECP2 (Homo sapiens)


name: ESTG binds ESR2:chaperone complex (Gallus gallus)


name: 3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-seryl-[protein] + ATP <=> 3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phospho-alpha-D-mannosyl)-L-seryl-[protein] + ADP + H(+)


name: FGFR1c binds to Klotho-bound FGF23 (Rattus norvegicus)


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Gallus gallus)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NAD(+) = (6R)-L-erythro-6,7-dihydrobiopterin + H(+) + NADH


name: alpha-D-xylose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-xylose


name: RNA Polymerase III Abortive Initiation At Type 3 Open Promoters (Homo sapiens)


name: ATP + L-glutamate + oxidized coenzyme F420-2 = ADP + H(+) + oxidized coenzyme alpha-F420-3 + phosphate


name: ATP + L-threonine => diphosphate + L-threonyl-5'-AMP


name: CSF3 dimer:CSFR binds CSFR (Gallus gallus)


name: L-alanine(out) + L-phenylalanine(in) => L-alanine(in) + L-phenylalanine(out)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Drosophila melanogaster)


name: BLT receptors can bind LTB4 (Drosophila melanogaster)


name: (2E,6E)-farnesal + H2O2 + L-cysteine => H2O + O2 + S-(2E,6E)-farnesyl-L-cysteine


name: a fatty acyl-CoA + phytol = a fatty acid phytyl ester + CoA


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Bos taurus)


name: ATP + cholate(in) + H2O <=> ADP + cholate(out) + H(+) + phosphate


name: an N-(fatty acyl)-L-leucine + H2O => a fatty acid + L-leucine


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Schizosaccharomyces pombe)


name: ADP(in) + ATP(out) <=> ADP(out) + ATP(in)


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine = 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 4 H(+) + 3 L-methionine


name: "anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase"


name: eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: cycloartenol + S-adenosyl-L-methionine => cyclolaudenol + H(+) + S-adenosyl-L-homocysteine


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Bos taurus)


name: 1,4-benzoquinone + H(+) + NADPH => hydroquinone + NADP(+)


name: a phenol + an aryl sulfate <=> a phenol + an aryl sulfate


name: A + a (2R)-2-hydroxycarboxylate = a 2-oxocarboxylate + AH2


name: ATP + holo-[peptidyl-carrier protein] + L-threonine => AMP + diphosphate + L-threonyl-[peptidyl-carrier protein]


name: a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-homocysteine


name: Calmodulin dissociates KRAS4B from the plasma membrane (Caenorhabditis elegans)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Mus musculus)


name: hydrogen sulfide + methyl-Co(III)-[methylated-thiol-specific corrinoid protein] => Co(I)-[methylated-thiol-specific corrinoid protein] + methanethiol


name: 3-phenylpyruvate + H(+) + NADH + NH4(+) => H2O + L-phenylalanine + NAD(+)


name: chloride(in) + nitrate(out) => chloride(out) + nitrate(in)


name: lithocholate + PAPS => lithocholate sulfate + PAP (Danio rerio)


name: a ganglioside GD3 + H2O = a ganglioside GM3 + N-acetylneuraminate


name: hydrolase activity, acting on ester bonds


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Homo sapiens)


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Sus scrofa)


name: 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one + 3 CO2 + 4 CoA => 12-methyltridecanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: pituitary adenylate cyclase-activating polypeptide receptor binding


name: decanoyl-CoA + H2O = adenosine 3',5'-bisphosphate + decanoyl-4'-phosphopantetheine + 2 H(+)


name: ABCB4 transports PC from plasma membrane to extracellular region (Homo sapiens)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Homo sapiens)


name: SEC4C,D bind GOSR2 and STX5 (Homo sapiens)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Dictyostelium discoideum)


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Xenopus tropicalis)


name: 2-oxobutanoate + L-tyrosine = (2S)-2-aminobutanoate + 3-(4-hydroxyphenyl)pyruvate


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Canis familiaris)


name: plastid PEP RNA polymerase core enzyme binding


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + viridiflorene


name: ATP + H2O + L-tryptophan <=> AMP + D-tryptophan + diphosphate + H(+)


name: 2 H(+) + IMP + 2 phosphate => 2 H2O + ITP


name: EP300 acetylates histone H2A, H2B, H3, H4 (Bos taurus)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Homo sapiens)


name: AH2 + alpha-N-dichloroacetyl-p-aminophenylserinol + 2 O2 <=> A + chloramphenicol + 2 H2O


name: acetylsalicylate + H2O => acetate + H(+) + salicylate


name: Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Bos taurus)


name: 3-hydroxybenzoate + H(+) + NADH + O2 = 2,5-dihydroxybenzoate + H2O + NAD(+)


name: 2'-deoxyadenosine(out) + H(+)(out) => 2'-deoxyadenosine(in) + H(+)(in)


name: Dephosphorylation of inactive SRC by PTPB1 (Bos taurus)


name: DCC interaction with Ezrin (Drosophila melanogaster)


name: NSF ATPase activity dissociates cis-SNARE (Danio rerio)


name: TrkA phosphorylates PLCG1 (Homo sapiens)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Canis familiaris)


name: H2O + N-phenylhydroxylamine + 2 NADP(+) <=> 2 H(+) + 2 NADPH + nitrobenzene


name: [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + O2 = glycine betaine + 2 H(+) + phosphate


name: Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Gallus gallus)


name: H(+) + N-ethylmaleimide + NADPH <=> N-ethylsuccinimide + NADP(+)


name: dihydrocurcumin + H(+) + NADPH => NADP(+) + tetrahydrocurcumin


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Mus musculus)


name: SLC22A1 transports Cipro into renal cell (Gallus gallus)


name: Parkin transfers Ub to misfolded proteins (Dictyostelium discoideum)


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Mus musculus)


name: acetate + vanillin => (E)-ferulate + H2O


name: H(+)(in) + sucrose(out) = H(+)(out) + sucrose(in)


name: GGT dimers hydrolyse APAP-SG (Sus scrofa)


name: RNF34 or RFFL ubiquitinates phosphorylated TP53 (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + a phenolic steroid => a phenolic steroid 3-O-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: AOX1 oxidises PXL to PDXate (Danio rerio)


name: Receptors CCR1, 2 and 8 bind CCL16 ligand (Homo sapiens)


name: 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA => 16-hydroxyhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: glycine + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + sarcosine


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Gallus gallus)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O <=> a fatty acid + H(+) + sn-glycero-3-phospho-L-serine


name: Transcriptional activation of FAS monomer gene by ChREBP:MLX (Homo sapiens)


name: Gq activation by TP receptor (Sus scrofa)


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Homo sapiens)


name: asperterpenoid A + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> asperterpenoid B + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: PI3K binds membrane-associated estrogen receptors (Mus musculus)


name: ADRM1:26S proteaseome binds USP14 (Danio rerio)


name: 4-aminoimidazole + H(+) + 2 H2O => N-formimidoylglycine + NH4(+)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + CoA


name: KIR2DS2 interacting with HLA-C group 1 (Cw3) (Mus musculus)


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Homo sapiens)


name: Activated FGFR3 phosphorylates PPTN11 (Canis familiaris)


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Gallus gallus)


name: Viral dsRNA:TLR3:TRIF complex recruits RIP1 (Homo sapiens)


name: M dimer is phosphorylated (Homo sapiens)


name: Association of gamma H2AX and NBS1 (Gallus gallus)


name: dihydro-6-demethylsterigmatocystin + S-adenosyl-L-methionine <=> dihydrosterigmatocystin + H(+) + S-adenosyl-L-homocysteine


name: 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: allantoate + H(+) => (S)-allantoin + H2O


name: ADP-ribosyl-[dinitrogen reductase] hydrolase activity


name: APS is phosphorylated to PAPS (Mycobacterium tuberculosis)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA


name: Activated FGFR1:p-FRS bind to PPTN11 (Rattus norvegicus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Homo sapiens)


name: CALCR binds gepants (Drosophila melanogaster)


name: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycerol + H(+) + sn-glycerol 3-phosphate => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O


name: Displacement of UNG glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: 2 H2O + NADP(+) + stigmasterol => H(+) + NADPH + O2 + sitosterol


name: a 1,2-diacylglycerol + a 1-acylglycerol <=> a triacylglycerol + glycerol


name: FUOM isomerises alpha-Fuc to beta-Fuc (Homo sapiens)


name: Proglucagon translocates from the ER Lumen to secretory granules (Rattus norvegicus)


name: H2O + N(4)-benzoylagmatine <=> agmatine + benzoate


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Rattus norvegicus)


name: bacterioruberin <=> bisanhydrobacterioruberin + 2 H2O


name: Transphosphorylation of pLIMK1 (Danio rerio)


name: a 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + H(+) + NADH + O2 <=> a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + 2 H2O + NAD(+)


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine <=> 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: keto-D-fructose 6-phosphate => D-allulose 6-phosphate


name: H(+) + NAD(+) + reduced 2[4Fe-4S]-[ferredoxin] <=> NADH + oxidized 2[4Fe-4S]-[ferredoxin]


name: SRD5A2 binds SRD5A2 inhibitors (Caenorhabditis elegans)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Homo sapiens)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Saccharomyces cerevisiae)


name: CES1 hydrolyses sacubitril to sacubitrilat (Sus scrofa)


name: alpha-D-glucose 1-phosphate + ATP + H(+) => ADP-alpha-D-glucose + diphosphate


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Saccharomyces cerevisiae)


name: D-glucarate + 3 H(+) + NADH => D-glucurono-3,6-lactone + 2 H2O + NAD(+)


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 7alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: EGFR phosphorylates GPNMB (Gallus gallus)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Sus scrofa)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)


name: 4 Fe(III)-[cytochrome c] + hydrazine <=> 4 Fe(II)-[cytochrome c] + 4 H(+) + N2


name: pro-SFTPC translocates from ER membrane to multivesicle body (Homo sapiens)


name: Phosphorylation and activation of PLCG (Sus scrofa)


name: D-ribulose + H(+) + NADH => D-arabinitol + NAD(+)


name: PTEN mRNA translation negatively regulated by microRNAs (Homo sapiens)


name: 5-(methylsulfanyl)-D-ribose + ATP => ADP + H(+) + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL (Homo sapiens)


name: PIP3 recruits PDK1 and AKT to the membrane (Saccharomyces cerevisiae)


name: CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine (Homo sapiens)


name: Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)


name: 1-octadecanoylglycerone 3-phosphate + hexadecan-1-ol => 1-O-hexadecylglycerone 3-phosphate + H(+) + octadecanoate


name: H2O + L-2-aminohexanoate + O2 <=> 2-oxohexanoate + H2O2 + NH4(+)


name: Ubiquitinated Orc1 enters the cytosol (Homo sapiens)


name: [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA = [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl](n) + n CoA


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (22R)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Homo sapiens)


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Danio rerio)


name: CYP2W1 oxidises INDOL (Dictyostelium discoideum)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Danio rerio)


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Canis familiaris)


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Rattus norvegicus)


name: Aquaporins passively transport water into cells (Danio rerio)


name: Polyubiquitination of substrate (Xenopus tropicalis)


name: Joining of adjacent Okazaki fragments (Canis familiaris)


name: holo-[ACP] + malonyl-CoA <=> CoA + malonyl-[ACP]


name: ent-sandaracopimaradien-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => ent-sandaracopimara-8(14),15-diene + O2 + reduced [NADPH--hemoprotein reductase]


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Xenopus tropicalis)


name: TRPA1 tetramer binds TRPA1 antagonists (Mus musculus)


name: decanedioyl-CoA + H2O <=> CoA + decanedioate + H(+)


name: Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA (Mus musculus)


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Caenorhabditis elegans)


name: ATP + taurocyamine = ADP + H(+) + N-phosphotaurocyamine


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoA => (9Z)-octadecenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol


name: a ubiquinone + H(+) + n Na(+)(in) + NADH <=> a ubiquinol + n Na(+)(out) + NAD(+)


name: 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 => 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H(+) + H2O2


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Bos taurus)


name: Activated protein C binds Protein S (Mus musculus)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Rattus norvegicus)


name: apoTF:TFRC dimer translocates from endosome membrane to plasma membrane (Bos taurus)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Canis familiaris)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Sus scrofa)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Rattus norvegicus)


name: PLOD3 binds Lysyl hydroxylated collagen propeptides (Homo sapiens)


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Gallus gallus)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Bos taurus)


name: soyasaponin III + UDP-beta-L-rhamnose => H(+) + soyasaponin I + UDP


name: Phosphorylation of YAP by LATS1 (Danio rerio)


name: SOCS-1 and SOCS-3 binds to p-JAK2 (Bos taurus)


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Drosophila melanogaster)


name: arginine + H2O => ornithine + urea [ARG1] (Caenorhabditis elegans)


name: GPI dimer isomerizes Fru(6)P to G6P (Dictyostelium discoideum)


name: (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + CO2 + CoA


name: oxaloacetate + propanoyl-CoA => (S)-methylmalonyl-CoA + pyruvate


name: cytidine(49) in tRNA(Asp) + S-adenosyl-L-methionine <=> 5-methylcytidine(49) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: Activation of RAC1 (Drosophila melanogaster)


name: CMP-N-acetyl-beta-neuraminate + ganglioside GM1 (d18:1(4E)/18:0) = CMP + ganglioside GD1a (18:1(4E)/18:0) + H(+)


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Sus scrofa)


name: B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac (Homo sapiens)


name: H2O + isomaltose => alpha-D-glucose + D-glucose


name: 5-aminopentanamide + H2O => 5-aminopentanoate + NH4(+)


name: Phosphorylation of APS (Canis familiaris)


name: ZFPM proteins bind GATA proteins (Drosophila melanogaster)


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Canis familiaris)


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Drosophila melanogaster)


name: PKG1 phosphorylates BK channels (Homo sapiens)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: 4-methylquinoline + A + H2O = 4-methylquinolin-2(1H)-one + AH2


name: ATP + dimethylallyl diphosphate <=> diphosphate + N(6)-(dimethylallyl)adenosine 5'-triphosphate


name: 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine


name: CYP2D6 4-hydroxylates debrisoquine (Homo sapiens)


name: VMAT1/2 can mediate the transport of biogenic amines (Homo sapiens)


name: SYK autophosphorylates (Rattus norvegicus)


name: 2-dehydro-3-deoxy-L-galactonate + H2O => L-galactonate


name: all-trans retinoic acid 18-hydroxylase activity


name: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a (Caenorhabditis elegans)


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Homo sapiens)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Mus musculus)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Mus musculus)


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + AH2 => 4-pyridoxate + A


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Rattus norvegicus)


name: GST dimers conjugate GSH with cytosolic substrates (Bos taurus)


name: (R)-carnitine(out) + O-acetyl-(R)-carnitine(in) => (R)-carnitine(in) + O-acetyl-(R)-carnitine(out)


name: a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Rattus norvegicus)


name: angiotensin-(1-9) + H2O = angiotensin-(1-7) + L-phenylalanyl-L-histidine


name: 4-chlorobenzoyl-CoA + H2O <=> 4-hydroxybenzoyl-CoA + chloride + H(+)


name: (R)-carnitinamide + H2O => (R)-carnitine + NH4(+)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Sus scrofa)


name: CTP(in) + dUMP(out) => CTP(out) + dUMP(in)


name: SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Rattus norvegicus)


name: acetaldehyde + CO2 => 3-oxopropanoate + H(+)


name: cholesterol + UDP-alpha-D-glucose => cholesteryl 3-beta-D-glucoside + H(+) + UDP


name: D-fructopyranose(out) + Na(+)(out) = D-fructopyranose(in) + Na(+)(in)


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Homo sapiens)


name: Caspase-mediated cleavage of E-Cadherin (Mus musculus)


name: CoA + H(+) + succinate => H2O + succinyl-CoA


name: Constitutive phosphorylation  by pERK1/2 (Saccharomyces cerevisiae)


name: 5-guanidino-2-oxopentanoate + a plastoquinol + NH4(+) => a plastoquinone + H2O + L-arginine


name: Expression of POU3F3 during nephron development (Homo sapiens)


name: androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] => 19-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: platelet-derived growth factor beta-receptor activity


name: glutamine + H2O => glutamate + NH4+ [GLS] (Mus musculus)


name: B-WICH recruits histone acetyltransferases (Mus musculus)


name: 1-O-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + butanoate + H(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(out) + ADP + H(+) + phosphate => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(in) + ATP + H2O


name: SLC25A10 mediates exchange of malate and phosphate (Caenorhabditis elegans)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Xenopus tropicalis)


name: SUMOylation of MDC1 with SUMO1 (Rattus norvegicus)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Saccharomyces cerevisiae)


name: 4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NAD(+) = 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + H(+) + NADH


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Homo sapiens)


name: Crk's SH3 domain engages C3G (Xenopus tropicalis)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Rattus norvegicus)


name: Nitric oxide is oxidized to nitrate (Homo sapiens)


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Xenopus tropicalis)


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)


name: FPGS-2 transforms THF to THFPG (Rattus norvegicus)


name: an N-(1,2 saturated very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(III)-[cytochrome b5] + H2O


name: 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H(+) => 6-deoxy-6-sulfo-D-fructose + ATP


name: 3'-dehydrocarminate + H2O2 => carminate + O2


name: 3-oxopropanoate + H2O + NADP(+) <=> 2 H(+) + malonate + NADPH


name: PTK6 phosphorylates ARHGAP35 (Danio rerio)


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Bos taurus)


name: Formation of tonofilament bundles (Gallus gallus)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate + H2O => (2Z,6E)-hedycaryol + diphosphate


name: ARL2:GTP:ARL2BP binds SLC25A4 (Mus musculus)


name: [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + H(+) + NADPH + O2 => [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B + H2O + NADP(+)


name: myo-inositol + S-adenosyl-L-methionine = 1D-4-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: histamine + S-adenosyl-L-methionine => H(+) + N(tau)-methylhistamine + S-adenosyl-L-homocysteine


name: Autophosphorylation of PDGFR mutant dimers (Homo sapiens)


name: USP28 deubiquitinates CLSPN and MYC (Canis familiaris)


name: p-Y420-FYN is phosphorylated on S21 (Bos taurus)


name: Recruitment of POLB to oxidatively damaged AP site (Bos taurus)


name: 4-aminobutanoate(out) + H(+)(out) => 4-aminobutanoate(in) + H(+)(in)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)


name: IRAK4 deficiency blocks formation of the MyD88-IRAK4 Myddosome in the TLR5 pathway (Homo sapiens)


name: SESN1,2 binds L-leucine and dissociates from GATOR2 (Gallus gallus)


name: ZnT8 transports zinc into the Golgi apparatus (Mus musculus)


name: SUMOylation of NR1H4 with SUMO1 (Rattus norvegicus)


name: leukotriene C4 <=> glutathione + leukotriene A4


name: RBBP7 binds histone H3 (Schizosaccharomyces pombe)


name: IL17RD binds p-2S MAP2Ks and MAPKs (Rattus norvegicus)


name: BP180 interacts intracellularly with plectin and integrin beta4 (Rattus norvegicus)


name: CDK1 phosphorylates condensin I (Homo sapiens)


name: Canonical WNT signaling through the atypical receptor RYK (Sus scrofa)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Drosophila melanogaster)


name: PKA phosphorylates GLI3 (Drosophila melanogaster)


name: (1R,2S,4R)-neodihydrocarveol + NAD(+) => (1R,4R)-dihydrocarvone + H(+) + NADH


name: JAK1 binds IL4R in IL4-bound IL4R1 (Gallus gallus)


name: Transcription of PPP1R15A (Homo sapiens)


name: (+)-artemisinate + 2 H(+) + NADPH => (+)-artemisinic aldehyde + H2O + NADP(+)


name: cholesterol + NADP(+) = 7-dehydrocholesterol + H(+) + NADPH


name: 2 Na(+)(out) + tauroallocholate(out) = 2 Na(+)(in) + tauroallocholate(in)


name: 8-oxo-dGDP + H2O <=> 8-oxo-dGMP + H(+) + phosphate


name: (E)-coniferaldehyde + AH2 => (E)-coniferol + A


name: 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Dictyostelium discoideum)


name: a 2'-O-methylribonucleotide in rRNA + H(+) + S-adenosyl-L-homocysteine => a ribonucleotide in rRNA + S-adenosyl-L-methionine


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Dictyostelium discoideum)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate <=> adenosine 5'-tetraphosphate + AMP + 2 H(+)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)


name: Addition of GlcNAc to position 5 by MGAT5 (Xenopus tropicalis)


name: Succinate <=> Fumarate (with FAD redox reaction on enzyme) (Danio rerio)


name: GLUT7 and GLUT11 transport glucose and fructose (Sus scrofa)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Sus scrofa)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Canis familiaris)


name: P4HB binds Collagen chains (Danio rerio)


name: MAP2K1 phosphorylates MAPK3 (Mus musculus)


name: Association of ADAM and B4GALT1 With ZP3 (Bos taurus)


name: SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Mus musculus)


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Caenorhabditis elegans)


name: CERK phosphorylates CERA to form C1P (Xenopus tropicalis)


name: acetyl-CoA + 2 H(+) + 2 malonyl-CoA = 2 CO2 + 3 CoA + triacetate lactone


name: Interleukin-5 is a homodimer (Sus scrofa)


name: ATP + hydrogencarbonate + propanoyl-CoA <=> ADP + H(+) + methylmalonyl-CoA + phosphate


name: glycyl-L-leucine + 2 H(+)(in) => glycyl-L-leucine(out) + 2 H(+)(out)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Saccharomyces cerevisiae)


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Sus scrofa)


name: 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Rattus norvegicus)


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate <=> (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Sus scrofa)


name: a menaquinone + succinate = a menaquinol + fumarate


name: The phagophore extends from the PIP3-enriched structure (Caenorhabditis elegans)


name: a (2E,4E)-dienoyl-CoA + H(+) + NADPH => a 4,5-saturated-(2E)-enoyl-CoA + NADP(+)


name: (S)-oxalosuccinate + H(+) => 2-oxoglutarate + CO2


name: Interaction of MyoD:E protein with MEF2 (Caenorhabditis elegans)


name: Internal Methylation of mRNA (Rattus norvegicus)


name: Active FLT3 binds to GRB10 (Canis familiaris)


name: alliin <=> 2-aminoprop-2-enoate + allylsulfenate


name: VWF multimer binds to collagen type I (Mus musculus)


name: Activation of JNK by DSCAM (Mus musculus)


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Rattus norvegicus)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 17alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O => an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Schizosaccharomyces pombe)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Sus scrofa)


name: CDK6 inhibitors bind CDK6 (Drosophila melanogaster)


name: TP53 stimulates GLS2 transcription (Homo sapiens)


name: (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H(+) => (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O


name: a 3-oxo-Delta(4)-steroid => a 3-oxo-Delta(5)-steroid


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Xenopus tropicalis)


name: 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O => 4 catechol + 3 O2


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Sus scrofa)


name: FOXO1 binds SREBF1 gene promoter (Homo sapiens)


name: a neolactoside IV(3)-alpha-GalNAc,IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O <=> a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + N-acetyl-alpha-D-galactosamine


name: IL35 binds IL27RA:IL12RB2 receptor (Bos taurus)


name: Activated NTRK3 binds SHC1 (Homo sapiens)


name: a 1,2-diacyl-sn-glycerol + phosphate => a 1,2-diacyl-sn-glycero-3-phosphate + H2O


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Bos taurus)


name: ABCE1 binds RNASEL, inhibiting it (Mus musculus)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Rattus norvegicus)


name: HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) (Mus musculus)


name: BRD7 binds TP53 and EP300 (Rattus norvegicus)


name: (R)-lactate + chloride + H(+) => (S)-2-chloropropanoate + H2O


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine <=> 2-[(3S)-3-carboxy-3-(methylamino)propyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-adenosyl-L-homocysteine


name: NEU3 hydrolyzes Neu5Ac from glycoconjugates (Homo sapiens)


name: 4-hydroxybenzoate(in) + H(+)(out) = 4-hydroxybenzoate(out) + H(+)(in)


name: asperaculane G + O2 + reduced [NADPH--hemoprotein reductase] <=> aculene D + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: BP230 interacts with keretin K5/K14 (Mus musculus)


name: ATP + citrate + N(5)-[(S)-citryl]-D-ornithine => AMP + diphosphate + H(+) + staphyloferrin A


name: SCARB1:ligand is endocytosed (Sus scrofa)


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Xenopus tropicalis)


name: Binding of the MCC complex to the APC/C complex (Homo sapiens)


name: JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Homo sapiens)


name: YWHAZ binds p-CBY:CTNNB1 (Drosophila melanogaster)


name: 3,4-dihydroxybenzoyl-5'-AMP + holo-[aryl-carrier protein] => 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + H(+)


name: putrescine + pyruvate => 4-aminobutanal + L-alanine


name: H2O + L-kynurenine = anthranilate + H(+) + L-alanine


name: Ubiquitinated TP53 translocates to the cytosol (Homo sapiens)


name: ATP + L-glutamate + tRNA(Gln) <=> AMP + diphosphate + L-glutamyl-tRNA(Gln)


name: methylmalonyl-CoA + N(6)-biotinyl-L-lysyl-[protein] => N(6)-carboxybiotinyl-L-lysyl-[protein] + propanoyl-CoA


name: Keratin tetramers bind to form unit length filaments (Sus scrofa)


name: UDP-alpha-D-glucose => H2O + UDP-4-dehydro-6-deoxy-alpha-D-glucose


name: acetyl-CoA + cyathatriol = 11-O-acetylcyathatriol + CoA


name: USP13 deubiquitinates BECN1,USP10 (Schizosaccharomyces pombe)


name: MAP3K8 is phosphorylated (Xenopus tropicalis)


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Homo sapiens)


name: 7-oxocholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3beta,26-dihydroxycholest-5-en-7-one + H2O + 2 oxidized [adrenodoxin]


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Danio rerio)


name: guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine


name: (2S)-sakuranetin + S-adenosyl-L-methionine <=> (2S)-naringenin 4',7-dimethyl ether + H(+) + S-adenosyl-L-homocysteine


name: 3-oxohexanoyl-[ACP] + CO2 + CoA => butanoyl-CoA + H(+) + malonyl-[ACP]


name: dTDP-beta-L-mycarose + erythronolide B <=> 3-O-alpha-L-mycarosylerythronolide B + dTDP + H(+)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Mus musculus)


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Homo sapiens)


name: 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + NAD(+) = 2,5-dichlorohydroquinone + H(+) + NADH


name: 2 a quinone + H(+) + NADH => 2 a 1,4-benzosemiquinone + NAD(+)


name: CHPF,CHSY3 transfer GalNAc to chondroitin (Drosophila melanogaster)


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Canis familiaris)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Danio rerio)


name: D-xylose + NADP(+) => D-xylono-1,5-lactone + H(+) + NADPH


name: Glucagon binds to Glucagon receptor (Bos taurus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphate + H(+)


name: 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoylglycerol <=> 1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: PEX19 binds class I peroxisomal membrane proteins (Dictyostelium discoideum)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Sus scrofa)


name: [phosphate](n) + ATP = [phosphate](n+1) + ADP


name: Estrogen-responsive CCND1 gene expression (Homo sapiens)


name: Activation of proMMP8 (Xenopus tropicalis)


name: 2-oxoglutarate + an N(3)-methylcytidine in mRNA + O2 <=> a cytidine in mRNA + CO2 + formaldehyde + succinate


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Caenorhabditis elegans)


name: MECP2 binds MEF2C gene promoter (Homo sapiens)


name: PNPLA4 hydrolyzes TAG (Plasmodium falciparum)


name: 1-propanol + 2 Fe(III)-[cytochrome c] <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + propanal


name: GAB1 phosphorylation by EGFR kinase (Mus musculus)


name: 1D-myo-inositol 1,4,5-trisphosphate + ATP => 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)


name: (R)-carnitine + eicosanoyl-CoA => CoA + O-eicosanoyl-(R)-carnitine


name: p-EPHB phosphorylates SDC2 (Homo sapiens)


name: RFC binding displaces Pol Alpha on the C-strand of the telomere (Bos taurus)


name: SULTs transfer (SO4)2- group to PREG (Bos taurus)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Bos taurus)


name: STAT5 dimers translocate to the nucleus (Homo sapiens)


name: (2S,3S)-hydroxyarginine <=> (2S,3R)-capreomycidine + H2O


name: Caspase-mediated cleavage of Desmoglein 1 (Xenopus tropicalis)


name: Phosphorylated STATs are released (Bos taurus)


name: CHOL translocates from cytosol to mitochondrial intermembrane space (Mus musculus)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Dictyostelium discoideum)


name: ATG12 binds ATG7 dimer (Drosophila melanogaster)


name: N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + O2 => H2O + N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Drosophila melanogaster)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (8R)-hydroperoxy-(9E,11Z,14Z)-eicosatrienoate


name: 3-phenylsuccinyl-CoA + succinate => phenylsuccinate + succinyl-CoA


name: beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => all-trans-beta-carotene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: D-ribitol 1-phosphate + H2O = phosphate + ribitol


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Bos taurus)


name: 3-[(1-carboxyvinyl)-oxy]benzoate + H2O + S-adenosyl-L-methionine <=> 6-amino-6-deoxyfutalosine + H(+) + hydrogencarbonate + L-methionine


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Sus scrofa)


name: ATP + dehydroepiandrosterone 3-sulfate(in) + H2O <=> ADP + dehydroepiandrosterone 3-sulfate(out) + H(+) + phosphate


name: NPAS4 binds ARNT (Caenorhabditis elegans)


name: 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + O2 <=> a 2'-deoxyadenosine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Mus musculus)


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Bos taurus)


name: acetyl-CoA + tetrahydroanabasine <=> ammodendrine + CoA


name: H2 + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: PPM1D dephosphorylates RUNX2 (Gallus gallus)


name: itaconate + L-cysteinyl-[protein] <=> S-(2,3-dicarboxypropyl)-L-cysteinyl-[protein]


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: (2E)-geranyl diphosphate = (1S,4R)-camphene + diphosphate


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Plasmodium falciparum)


name: 3'-phosphoadenylyl sulfate + pregnenolone <=> adenosine 3',5'-bisphosphate + H(+) + pregnenolone sulfate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acyl-(4R)-4-hydroxysphinganine <=> a 1,2-diacyl-sn-glycerol + an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol


name: ADP + D-glucosamine => AMP + D-glucosamine 6-phosphate + H(+)


name: succinate + FAD <=> fumarate + FADH2 (Gallus gallus)


name: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid IVA <=> a 2-acyl-sn-glycero-3-phosphocholine + a lipid IVB


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Caenorhabditis elegans)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Release of Cytochrome c from mitochondria (Drosophila melanogaster)


name: "3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin)"


name: CHUK, IKBKB and IKBKG form IKK complex (Bos taurus)


name: (3R)-hydroxyoctanoyl-CoA + NADP(+) = 3-oxooctanoyl-CoA + H(+) + NADPH


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Sus scrofa)


name: KDM5A-D demethylate Me3K5-histone H3 (Bos taurus)


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Sus scrofa)


name: [LarE protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine <=> [LarE protein]-dehydroalanine + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide


name: homogentisate + O2 <=> 4-maleylacetoacetate + H(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2 = 19-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: aklavinone + dTDP-beta-L-rhodosamine <=> aclacinomycin T + dTDP + 2 H(+)


name: quercetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = H(+) + quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP


name: acetyl-CoA + D-glutamine <=> CoA + H(+) + N-acetyl-D-glutamine


name: 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 23S,25-dihydroxy-24-oxocholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: (E)-feruloyl-CoA + 16-hydroxyhexadecanoate = 16-feruloyloxyhexadecanoate + CoA


name: CTP-dependent diacylglycerol kinase activity


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2) = beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2)


name: (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein] => AMP + 2 H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: 26Sproteasome degrades K48polyUb-NIK (Bos taurus)


name: Bitter compound binds bitter taste receptor (TAS2R) (Sus scrofa)


name: beta-alanine + L-arginine <=> 3-guanidinopropanoate + L-ornithine


name: Caspase mediated cleavage of beta-catenin (Canis familiaris)


name: IRAK1 induces oligomerisation of TRAF6 (Drosophila melanogaster)


name: HDACs deacetylate p-STAT3 dimers (Canis familiaris)


name: Exogenous soluble antigen targeted to more stable early endosome (Gallus gallus)


name: Association of procollagen type XVI (Bos taurus)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: PM20D1 hydrolyzes oleoyl-phe (Homo sapiens)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Bos taurus)


name: SFN dimer binds CDK1 and CCNB1 (Rattus norvegicus)


name: Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers (Homo sapiens)


name: (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + NADP(+) => (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA + H(+) + NADPH


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: MIA2 and MIA3 dissociate from procollagen VII vesicle (Homo sapiens)


name: NLRP3 activation by small molecules (Gallus gallus)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Sus scrofa)


name: 10-hydroxyoctadecanoate + NAD(+) => 10-oxooctadecanoate + H(+) + NADH


name: SGT1:HSP90 binds inactive NLRP3 (Danio rerio)


name: PPP1R3C binds to glycogen:GYG2:GYS2 (Sus scrofa)


name: 5,6,7,8-tetrahydropteridine + NAD(+) = 6,7-dihydropteridine + H(+) + NADH


name: Binding of RRN3 to RNA Polymerase I (Bos taurus)


name: Beta-catenin recruits CDC73 and LEO1 (Bos taurus)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Canis familiaris)


name: XYLB phosphorylates D-xylulose (Schizosaccharomyces pombe)


name: diphthamide-[translation elongation factor 2] + NAD(+) => H(+) + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] + nicotinamide


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + CoA => a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + an acyl-CoA


name: PXLP-K754-GLDC dimer decarboxylates Gly (Drosophila melanogaster)


name: PTK6 phosphorylates KHDRBS2 (Rattus norvegicus)


name: RUNX3 translocates to the nucleus (Drosophila melanogaster)


name: Cdc6 protein is phosphorylated by CDK (Sus scrofa)


name: (+)-dehydrodiconiferyl alcohol + H(+) + NADPH = (R)-isodihydrodehydrodiconiferyl alcohol + NADP(+)


name: Exocytosis of secretory granule membrane proteins (Drosophila melanogaster)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Sus scrofa)


name: a (2E,4Z)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: NPAS4 gene transcription in non-neuronal cells is repressed by REST (Homo sapiens)


name: 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O => prephenate + S-adenosyl-L-methionine


name: Collagen type II degradation by MMP15 (Rattus norvegicus)


name: Association of procollagen type IV (Rattus norvegicus)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Bos taurus)


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Bos taurus)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Drosophila melanogaster)


name: acetyl-CoA + CO2 + NADPH => CoA + NADP(+) + pyruvate


name: (8Z,11Z,14Z)-heptadecatrienal + A + H2O = (8Z,11Z,14Z)-heptadecatrienoate + AH2 + H(+)


name: Phosphorylation of CARMA1 by PKC-theta (Mus musculus)


name: histidine => urocanate + NH4+ (Mus musculus)


name: (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one + 5-cis-10'-apo-lycopenal => 5-cis-lycopene + O2


name: GALK1 phosphorylates Gal to Gal1P (Canis familiaris)


name: CYP19A1 hydroxylates TEST to EST17b (Sus scrofa)


name: (9Z,12Z)-octadecadienoyl-CoA + H(+) + malonyl-CoA <=> (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA


name: RAS GEFs promote RAS nucleotide exchange (Canis familiaris)


name: HNF6- and FGF10-dependent synthesis of PDX1 protein (Homo sapiens)


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Sus scrofa)


name: 3',5'-cyclic GMP(out) + a dicarboxylate(in) = 3',5'-cyclic GMP(in) + a dicarboxylate(out)


name: EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Bos taurus)


name: an N-acylsphing-4-enine 1-phosphate(in) = an N-acylsphing-4-enine 1-phosphate(out)


name: 13-cis-lycopene + O2 = (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one + 13-cis-10'-apo-lycopenal


name: H(+) + NADPH + zeatin => dihydrozeatin + NADP(+)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Rattus norvegicus)


name: CCNG1 recruits PP2A-PPP2R5C to MDM2 (Xenopus tropicalis)


name: coenzyme M + methyl-Co(III)-[tetramethylammonium-specific corrinoid protein] = Co(I)-[tetramethylammonium-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: "[methyl-Co(III) tetramethylammonium-specific corrinoid protein]:coenzyme M methyltransferase"


name: MTMR4 binds phosphorylated SMAD2/3 (Rattus norvegicus)


name: acetyl-CoA + H(+) + malonyl-[ACP] => 3-oxobutanoyl-[ACP] + CO2 + CoA


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP


name: CoA + O-decanoyl-(R)-carnitine => (R)-carnitine + decanoyl-CoA


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Drosophila melanogaster)


name: a 1-hexacosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a 1-[(17Z)-hexacos-17-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Electron transfer from reduced cytochrome c to molecular oxygen (Bos taurus)


name: (S)-malate(in) + phosphate(out) = (S)-malate(out) + phosphate(in)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-ethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: D-mannitol + NAD(+) => D-fructose + H(+) + NADH


name: 2-oxoglutarate(in) + prostaglandin F2alpha(out) => 2-oxoglutarate(out) + prostaglandin F2alpha(in)


name: Abortive termination of early transcription elongation by DSIF:NELF (Saccharomyces cerevisiae)


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Sus scrofa)


name: Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Canis familiaris)


name: GSK3B phosphorylates p-NFE2L2 (Rattus norvegicus)


name: ESR1:ESTG and EP300 are recruited to TFF3 promoter (Homo sapiens)


name: 27-hydroxycholesterol is 7alpha-hydroxylated (Canis familiaris)


name: C-terminal Hh fragments are bound by lectins (Rattus norvegicus)


name: Association of Securin with Cdc20:APC/C complex (Mus musculus)


name: 4-methyl-2-oxopentanoate(in) + H(+)(in) => 4-methyl-2-oxopentanoate(out) + H(+)(out)


name: RANBP2 SUMOylates SP100 with SUMO2 (Mus musculus)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Caenorhabditis elegans)


name: L1-FGFR cis-heterodimerization (Homo sapiens)


name: benzoyl-AMP + CoA <=> AMP + benzoyl-CoA + H(+)


name: D-glucose + NADP(+) = D-glucono-1,5-lactone + H(+) + NADPH


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Saccharomyces cerevisiae)


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Dictyostelium discoideum)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Gallus gallus)


name: ERCC1:XPF cleaves flaps generated by SSA (Homo sapiens)


name: Keratin type I/type II heterodimers form tetramers (Rattus norvegicus)


name: RHOD auto-activates (Caenorhabditis elegans)


name: H(+) + L-homoserine + tRNA(Ser) => H2O + L-homoseryl-tRNA(Ser)


name: 1-O-alkyl-3-acylglycerol + an acyl-CoA = 1-O-alkyl-2,3-diacylglycerol + CoA


name: a fatty acyl-[ACP] + H(+) + malonyl-[ACP] <=> a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]


name: (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine => S-(5-deoxy-D-ribos-5-yl)-L-homocysteine


name: PANK1/3 phosphorylate PanK (Mus musculus)


name: H2O + octanoylglycerol = glycerol + H(+) + octanoate


name: 2-oxoglutarate + L-aspartate <=> L-glutamate + oxaloacetate


name: Formation of the Cleavage and Polyadenylation Complex (Bos taurus)


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Sus scrofa)


name: a dicarboxylate(in) + prostaglandin E2(out) = a dicarboxylate(out) + prostaglandin E2(in)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Sus scrofa)


name: a fatty acyl-[ACP] + H2O = a fatty acid + H(+) + holo-[ACP]


name: (2E,6E)-farnesyl diphosphate => (-)-alpha-isocomene + diphosphate


name: (5S)-hydroperoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate = (5S,6S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: 1-phenylpropan-1-one + L-alanine => 1-phenylpropylamine + pyruvate


name: ATP + guanine(out) + H2O <=> ADP + guanine(in) + H(+) + phosphate


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Canis familiaris)


name: hexadecanoyl-CoA + octadecan-1-ol = CoA + octadecanyl hexadecanoate


name: Formation of the closed pre-initiation complex (Gallus gallus)


name: adenosine + O2 = 5'-dehydroadenosine + H2O2


name: 11-cis-retinol + H(+) + hexadecanoate => all-trans-retinyl hexadecanoate + H2O


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Caenorhabditis elegans)


name: USP25 deubiquitinates DDX58 (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + A + 2 H2O => (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + AH2 + O2


name: 6-deoxotyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + typhasterol


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Homo sapiens)


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Rattus norvegicus)


name: (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+) => (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADPH + O2


name: enterobactin(in) + H(+)(out) = enterobactin(out) + H(+)(in)


name: Co(I)-[trimethylamine-specific corrinoid protein] + H(+) + methyl-coenzyme M => coenzyme M + methyl-Co(III)-[trimethylamine-specific corrinoid protein]


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Schizosaccharomyces pombe)


name: MAPK6 is degraded by the 26S proteasome (Mus musculus)


name: acetyl-AMP + cytidine(34) in elongator tRNA(Met) => AMP + H(+) + N(4)-acetylcytidine(34) in elongator tRNA(Met)


name: Dephosphorylation of pL1 (Y1176) (Homo sapiens)


name: (4R)-hydroxysphing-(8Z)-enine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphing-(8Z)-enine


name: a menaquinol + 2 H(+)(in) + nitrate <=> a menaquinone + 2 H(+)(out) + H2O + nitrite


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] = 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin]


name: Phosphorylation of Cx43 by c-src (Homo sapiens)


name: glutathione S-conjugate carboxypeptidase activity


name: Expression of GATA4 in lateral plate mesoderm (Homo sapiens)


name: Orexin 2 receptor can bind orexin-B neuropeptide (Gallus gallus)


name: H2O + N-tetradecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-tetradecanoylethanolamine


name: coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin]


name: Necl-2:Nectin 3 trans heterodimer interaction (Rattus norvegicus)


name: (9Z)-octadecenoate + H(+) + sn-glycerol 3-phosphocholine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: ATP + H2O + L-leucine(out) <=> ADP + H(+) + L-leucine(in) + phosphate


name: Initial activation of proMMP2 by MMP14 (Caenorhabditis elegans)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains (Sus scrofa)


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Canis familiaris)


name: HEXB cleaves the terminal GalNAc from DS (Dictyostelium discoideum)


name: RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity


name: AKT1 E17K mutant phosphorylates CREB1 (Homo sapiens)


name: DPH6 ligates ammonium to diphthine-EEF2 (Homo sapiens)


name: RAC2 binds effectors at the phagocytic vesicle membrane (Gallus gallus)


name: formate transmembrane transporter activity


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Rattus norvegicus)


name: (2E,6E)-farnesol + H(+) + NADPH + O2 <=> (2E,6E)-omega-hydroxy-farnesol + H2O + NADP(+)


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Bos taurus)


name: Generation of CLIP from lip10 (Rattus norvegicus)


name: HDAC8 deacetylates histones (Homo sapiens)


name: Increased PIP3 levels recruit DAkt1 to the membrane (Drosophila melanogaster)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Gallus gallus)


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate => CO2 + 2 H2O + NADP(+) + proviolacein


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Canis familiaris)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Bos taurus)


name: GRB2:SOS1 complex binds to the active receptor (Canis familiaris)


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] => (2S)-2-hydroxynaringenin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)


name: Ubiquitinated Orc1 enters the cytosol (Caenorhabditis elegans)


name: CBL ubiquitinates FRS2 and FGFR2 (Gallus gallus)


name: 2,2-dimethylsuccinate(in) + 3 Na(+)(in) => 2,2-dimethylsuccinate(out) + 3 Na(+)(out)


name: 2-oxoglutaramate + L-alanine => L-glutamine + pyruvate


name: SERPINA5 binds activated protein C (Sus scrofa)


name: Abortive Initiation Before Second Transition (Rattus norvegicus)


name: dihydrocarvone + H(+) + NADPH + O2 <=> 6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+)


name: cholesterol monooxygenase (side-chain-cleaving) activity


name: NAALADases hydrolyse NAAG (Canis familiaris)


name: ESD dimer hydrolyses S-FGSH to GSH (Sus scrofa)


name: NT5E:Zn2+ hydrolyses NAD+ (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecylglycerol => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Rattus norvegicus)


name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A (E. coli) <=> beta-L-Ara4N-lipid A (E. coli) + di-trans,octa-cis-undecaprenyl phosphate


name: DCAKD phosphorylates DP-CoA (Canis familiaris)


name: 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP => L-seryl-[EGF-like domain protein] + UDP-alpha-D-glucose


name: (R)-lipoate + ATP + H(+) => (R)-lipoyl-5'-AMP + diphosphate


name: Phenol can form a sulfate conjugate (Mus musculus)


name: (R)-6-hydroxynicotine + AH2 => (R)-nicotine + A + H2O


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Bos taurus)


name: Binding of TFIIIA To type 1 Promoter (Bos taurus)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Rattus norvegicus)


name: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA <=> 5'-deoxyadenosine + 5-(carboxymethyl)uridine(34) in tRNA + CoA + 2 H(+) + L-methionine


name: (2E,11Z)-octadecadienoyl-CoA + H(+) + NADPH = (11Z)-octadecenoyl-CoA + NADP(+)


name: ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans (Canis familiaris)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Gallus gallus)


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate => 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: Association of Emi1 with Cdh1 (Mus musculus)


name: Interleukin-5 receptor alpha subunit binds Interleukin-5 (Canis familiaris)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Sus scrofa)


name: Loading of PCNA - Sliding Clamp Formation (Bos taurus)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Sus scrofa)


name: H(+) + NADPH + salutaridine => (7S)-salutaridinol + NADP(+)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Homo sapiens)


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Rattus norvegicus)


name: cAMP dissociates PKA, promoting GLI processing (Caenorhabditis elegans)


name: Proteasome degrades polyubiquitinated PTEN (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: HSP90 is inactivated by binding to benzaquinoid ansamycins (Homo sapiens)


name: ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Bos taurus)


name: Release of p-STAT2:p-STAT1 dimer (Bos taurus)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Caenorhabditis elegans)


name: Formation of ARC coactivator complex (Sus scrofa)


name: acetyl-CoA + GDP-alpha-D-perosamine <=> CoA + GDP-N-acetyl-alpha-D-perosamine + H(+)


name: 2-oxoglutarate + 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate => 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + L-glutamate


name: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose <=> alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: a long-chain fatty aldehyde + holo-[ACP] + NADP(+) = a long-chain fatty acyl-[ACP] + H(+) + NADPH


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Bos taurus)


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA


name: BTK in active Gq-BTK complex is activated (Bos taurus)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (12S)-hydroperoxy-(8Z,10E,14Z)-eicosatrienoate


name: dAMP(out) + phosphate(in) => dAMP(in) + phosphate(out)


name: N(6)-methyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine


name: receptor serine/threonine kinase binding


name: GDP-beta-L-fucose + L-seryl-[protein] => 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + GDP + H(+)


name: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose => dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate


name: VMAT1/2 can mediate the transport of biogenic amines (Canis familiaris)


name: H2O + N(1)-acetylspermidine + O2 => 3-aminopropanal + H2O2 + N-acetylputrescine


name: CASP9 is phosphorylated at T412 (Canis familiaris)


name: Somatostatin receptors bind somatostatin and cortistatin (Bos taurus)


name: cytidine(32) in tRNA(Thr) + S-adenosyl-L-methionine => H(+) + N(3)-methylcytidine(32) in tRNA(Thr) + S-adenosyl-L-homocysteine


name: H2O + O2 + propionate 3-nitronate => 3-oxopropanoate + H(+) + H2O2 + nitrite


name: (R)-2-hydroxy-4-methylpentanoate + NAD(+) <=> 4-methyl-2-oxopentanoate + H(+) + NADH


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H(+) + S-adenosyl-L-homocysteine


name: dopamine + L-glutaminyl-[protein] <=> 5-dopaminyl-L-glutamyl-[protein] + NH4(+)


name: D-fructose + 2 Fe(II)-[cytochrome c] + 2 H(+) => D-mannitol + 2 Fe(III)-[cytochrome c]


name: all-trans-5,6-epoxyretinoyl-1-O-(beta-D-glucuronate) + UDP => all-trans-5,6-epoxyretinoate + UDP-alpha-D-glucuronate


name: Defective AVP mutants do not bind AVPR1A,B (Homo sapiens)


name: An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Mus musculus)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Sus scrofa)


name: Formation of the RBBP5:ASH2L heterodimer (Sus scrofa)


name: 7-deoxyloganetic aldehyde + O2 + reduced [NADPH--hemoprotein reductase] <=> 7-deoxyloganetate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Homo sapiens)


name: RHOT2 GEFs activate RHOT2 (Homo sapiens)


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Gallus gallus)


name: (2E)-decenoyl-CoA + NADP(+) = (2E,4E)-decadienoyl-CoA + H(+) + NADPH


name: MRN complex bound to shortened telomeres recruits ATM (Rattus norvegicus)


name: PGM1:Mg2+ isomerises G1P to G6P (Saccharomyces cerevisiae)


name: a 2-oxocarboxylate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid


name: 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase] => AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase]


name: a 2-acylglycerol + ATP = a 2-acyl-sn-glycerol 3-phosphate + ADP + H(+)


name: SUMOylation of ING2 with SUMO1 (Danio rerio)


name: SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: 5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA + S-adenosyl-L-homocysteine => 5-(carboxymethyl)uridine(34) in tRNA + S-adenosyl-L-methionine


name: D-serine transmembrane transporter activity


name: (4R)-ipsdienol + NAD(+) => H(+) + ipsdienone + NADH


name: TRPV1 binds TRPV1 agonists (Mus musculus)


name: ADP + H(+) + N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein] => ATP + N(6)-(D-fructosyl)-L-lysyl-[protein]


name: acetyl-CoA + L-glutamate <=> CoA + H(+) + N-acetyl-L-glutamate


name: Auto-ubiquitination of TRAF6 (Mus musculus)


name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Sus scrofa)


name: AUF1:mRNA complex is destroyed (Drosophila melanogaster)


name: RUNX2 and RB1 bind the BGLAP gene promoter (Homo sapiens)


name: 17beta-estradiol + UDP-alpha-D-glucuronate <=> 17beta-estradiol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: Expression of CRYPTOCHROME-2 (Homo sapiens)


name: Expression of HAND2 in cardiogenesis (Homo sapiens)


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Dictyostelium discoideum)


name: Cohesin binds PDS5 and WAPAL (Sus scrofa)


name: IDUA hydrolyses Heparan sulfate chain(6) (Mus musculus)


name: WWTR1 binds SMAD2/3:SMAD4 heterotrimer (Rattus norvegicus)


name: N-hydroxy-L-valine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-valine + oxidized [NADPH--hemoprotein reductase]


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Danio rerio)


name: HSP70 binds to HSP40:nascent protein (Bos taurus)


name: (S)-dihydroorotate + fumarate = orotate + succinate


name: (9Z,12Z,15Z)-octadecatrienoate + O2 <=> (8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate


name: ERBB2 KD mutants trans-autophosphorylate (Homo sapiens)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Caenorhabditis elegans)


name: FAR1 reduces PalmCoA to HXOL (Sus scrofa)


name: Activated ATM phosphorylates ABL1 (Drosophila melanogaster)


name: Ral-GDS binds to Ras-GTP (Canis familiaris)


name: 11-cis-retinol--[retinol-binding protein] + NAD(+) = 11-cis-retinal--[retinol-binding protein] + H(+) + NADH


name: aminoacetaldehyde + CO2 + H(+) + succinate + sulfite => 2-oxoglutarate + O2 + taurine


name: (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA + H(+) + NADPH => (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + NADP(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+)


name: ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+)


name: Serum albumin binds 2-lysophosphatidylcholine (Rattus norvegicus)


name: L-seryl-[protein] + NAD(+) => H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-seryl-[protein]


name: beta-D-glucosyl crocetin + UDP-alpha-D-glucose => bis(beta-D-glucosyl) crocetin + UDP


name: ATP + L-pyrrolysine + tRNA(Pyl) => AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl)


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Mus musculus)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Dictyostelium discoideum)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Caenorhabditis elegans)


name: Release of E3 from polyubiquitinated substrate (Gallus gallus)


name: all-trans-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: HV1-mediated H+ transfer (Xenopus tropicalis)


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Schizosaccharomyces pombe)


name: 7-epi-cylindrospermopsin + CO2 + succinate => 2-oxoglutarate + 7-deoxycylindrospermopsin + O2


name: 2 H(+) + H2O + N-carbamoylputrescine <=> CO2 + NH4(+) + putrescine


name: PIAS4 SUMOylates PARP1 with SUMO1 (Mus musculus)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-CoA => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA


name: (11Z,14Z,17Z)-eicosatrienoate + O2 <=> 12-hydroperoxy-(10E,14Z,17Z)-eicosatrienoate


name: "secondary-alkyl amine dehydrogenase [NAD(P)(+)]"


name: N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine <=> 2 H(+) + N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine


name: a 5'-end triphospho-(purine-ribonucleoside) in mRNA + H2O = a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) + phosphate


name: Na(+)(out) + O-propanoyl-(R)-carnitine(out) <=> Na(+)(in) + O-propanoyl-(R)-carnitine(in)


name: 8-methylthiopropyl glucosinolate S-oxygenase activity


name: (E)-5-hydroxyferuloyl-CoA + S-adenosyl-L-methionine => (E)-sinapoyl-CoA + H(+) + S-adenosyl-L-homocysteine


name: an N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O = 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + O2


name: Initial activation of proMMP13 by MMP3 (Bos taurus)


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Homo sapiens)


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Drosophila melanogaster)


name: cis-4-hydroxy-L-proline + CO2 + succinate => 2-oxoglutarate + L-proline + O2


name: TPX2 promotes AURKA autophosphorylation (Sus scrofa)


name: ABHD6,12 hydrolyse 3AG (Xenopus tropicalis)


name: Part of pro-beta-NGF is processed to mature beta-NGF (Gallus gallus)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Dictyostelium discoideum)


name: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate


name: a 1-acyl-sn-glycero-3-phosphate + a fatty acyl-[ACP] => a 1,2-diacyl-sn-glycero-3-phosphate + holo-[ACP]


name: aminoacetone + CO2 + NADPH => L-allo-threonine + NADP(+)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Caenorhabditis elegans)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Mus musculus)


name: acetyl-CoA + H2O + pyruvate <=> (3R)-citramalate + CoA + H(+)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Homo sapiens)


name: ATP + H2O + phosphate(out) <=> ADP + H(+) + 2 phosphate(in)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Canis familiaris)


name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Dictyostelium discoideum)


name: S-adenosyl-L-methionine => L-homoserine lactone + S-methyl-5'-thioadenosine


name: FAICAR => IMP + H2O (Caenorhabditis elegans)


name: RHOU binds effectors at the plasma membrane (Gallus gallus)


name: ATP + CoA + nonanoate => AMP + diphosphate + nonanoyl-CoA


name: Formation of Classical C3 convertase (C4b:C2a complex) (Xenopus tropicalis)


name: CFTR transports Cl- from cytosol to extracellular region (Xenopus tropicalis)


name: GRK2 binds CALM1:4Ca2+ (Canis familiaris)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Bos taurus)


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Sus scrofa)


name: [hyaluronan](n) = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O


name: Conversion of C2 into C2a and C2b (Mus musculus)


name: 2 H2O + NADP(+) + versicolorin A => H(+) + NADPH + O2 + versicolorin B


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Dictyostelium discoideum)


name: PAQR3 binds inactive RAFs (Rattus norvegicus)


name: 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate => all-trans-nonaprenyl diphosphate + H(+) + homogentisate


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Dictyostelium discoideum)


name: SRD5A2 dehydrogenates TEST to DHTEST (Rattus norvegicus)


name: A + a 2,3-saturated acyl-CoA <=> a 2,3-dehydroacyl-CoA + AH2


name: PHF8 demethylates histone H4K20me1 (Rattus norvegicus)


name: Dephosphorylation of PAG by SHP2 (Bos taurus)


name: IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments (Bos taurus)


name: Caspase-mediated cleavage of plakophilin-1 (Caenorhabditis elegans)


name: 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H2O = (9Z,12Z)-octadecadienoate + a 1-acyl-sn-glycero-3-phosphoethanolamine + H(+)


name: dUTP + H2O => dUMP + pyrophosphate (Plasmodium falciparum)


name: D-cellopentaonate + H(+) => D-cellopentaono-1,5-lactone + H2O


name: E2F6:TFDP1 binds to MGA:MAX (Drosophila melanogaster)


name: geranylgeranyl-bacteriochlorophyllide a + 3 H(+) + 3 NADPH => bacteriochlorophyll a + 3 NADP(+)


name: 8-O-methylsterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> aflatoxin B1 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase]


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Gallus gallus)


name: AMP + diphosphate + heptadecanoyl-CoA => ATP + CoA + heptadecanoate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + L-phenylalanine => H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-L-phenylalanine


name: thiosulfate transmembrane transporter activity


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Homo sapiens)


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Gallus gallus)


name: NQO2:FAD dimer reduces quinones to hydroquinones (Sus scrofa)


name: RHOA binds effectors at the ER membrane (Xenopus tropicalis)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Gallus gallus)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Danio rerio)