name: p-S225-SPHK1 localizes to cytosol (Saccharomyces cerevisiae)


name: NME1,2 hexamers phosphorylate RBV-DP (Caenorhabditis elegans)


name: a very-long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(out) + glutarate(in) <=> 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(in) + glutarate(out)


name: H(+)(in) + L-ornithine(out) => H(+)(out) + L-ornithine(in)


name: (5Z)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2 H(+) + NADH + O2 + precorrin-3A => H2O + NAD(+) + precorrin-3B


name: c-src associates with Cx43 in gap junctions (Sus scrofa)


name: 4-hydroxyphenylglyoxylate + H2O2 => (S)-4-hydroxymandelate + O2


name: ATP + citrate + CoA => (3S)-citryl-CoA + ADP + phosphate


name: ST3GAL2,3 transfer Neu5Ac to gangliosides (Xenopus tropicalis)


name: (20S)-hydroxypregn-4-en-3-one + NAD(+) = H(+) + NADH + progesterone


name: a (2R,3S)-2-alkyl-3-hydroxyalkanoate + ATP => a cis-3-alkyl-4-alkyloxetan-2-one + AMP + diphosphate


name: Proteasomal cleavage of substrate (Plasmodium falciparum)


name: Dissociation of RAS:RAF complex (Bos taurus)


name: HCO3- transport through ion channel (Caenorhabditis elegans)


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Caenorhabditis elegans)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Mus musculus)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Sus scrofa)


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Sus scrofa)


name: a monoamide of a dicarboxylate + H2O = a dicarboxylate + NH4(+)


name: hexadecanoyl phosphate + sn-glycerol 3-phosphate = 1-hexadecanoyl-sn-glycero-3-phosphate + phosphate


name: Association of procollagen type II (Gallus gallus)


name: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH


name: (2E,6E)-farnesyl diphosphate + H2O <=> (1S,6S,7R)-sesquipiperitol + diphosphate


name: ATP + biotin + H(+) = biotinyl-5'-AMP + diphosphate


name: MHC class I protein binding, via lateral surface


name: N-decanoyl-(2S)-hydroxyglycine <=> decanamide + glyoxylate


name: IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Saccharomyces cerevisiae)


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Homo sapiens)


name: Edg-4 lysophosphatidic acid receptor binding


name: kainate receptor binds glutamate (Caenorhabditis elegans)


name: (20S)-hydroxypregn-4-en-3-one + NADP(+) => H(+) + NADPH + progesterone


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Drosophila melanogaster)


name: dodecanoyl-CoA + hexadecan-1-ol => CoA + hexadecanyl dodecanoate


name: NUDT16 hydrolyses IDP to IMP (Sus scrofa)


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Rattus norvegicus)


name: L-seryl-[protein] + pentanoyl-CoA => CoA + O-pentanoyl-L-seryl-[protein]


name: [protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide <=> [protein]-dithiol + 2 AH2 + H(+) + sulfite


name: (R)-carnitine + butanoyl-CoA => CoA + O-butanoyl-(R)-carnitine


name: RhCG mediates ammonium efflux out of kidney collecting duct cells (Rattus norvegicus)


name: Caspase-7 translocates to the nucleus (Xenopus tropicalis)


name: FNTA:FNTB transfers FARN to GNGT1 (Drosophila melanogaster)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O => an N-acyl-sphingoid base + lactose


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Saccharomyces cerevisiae)


name: Dimerization of PERK (Caenorhabditis elegans)


name: JAK1-activated RAF1 phosphorylates MAPKs (Rattus norvegicus)


name: RND3 binds effectors (Xenopus tropicalis)


name: ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate => ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine


name: PA is dephosphorylated to DAG by LPIN (Saccharomyces cerevisiae)


name: [sulfur-carrier protein]-L-cysteine + L-cysteine = [sulfur-carrier protein]-S-sulfanyl-L-cysteine + L-alanine


name: acetyl-CoA + S-(2-aminoethyl)-homocysteine <=> CoA + H(+) + S-(2-acetamidoethyl)-homocysteine


name: Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + octadecanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin]


name: PSD-95 binds NMDA receptor (Mus musculus)


name: (2S)-2-hydroxy-3,3-dimethylbutanenitrile => 2,2-dimethylpropanal + hydrogen cyanide


name: Exogenous soluble antigen targeted to more stable early endosome (Xenopus tropicalis)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR3 (Canis familiaris)


name: Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 (Canis familiaris)


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine = H(+) + kanamycin X + UDP


name: NEIL1,NEIL2 recruits POLB to incised AP site (Xenopus tropicalis)


name: Phosphorylation of p-KIT on Y900 by Src kinases (Danio rerio)


name: STON2 is neddylated (Drosophila melanogaster)


name: Active G alpha (z) binds RGS proteins (Mus musculus)


name: ECE2 cleaves EDN1(53-90) (Xenopus tropicalis)


name: Vesicle budding (Caenorhabditis elegans)


name: CYP3A4, CYP2B6 bind ritonavir (Danio rerio)


name: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity


name: L-glyceraldehyde 3-phosphate reductase activity


name: F2R:ARRB2 binds MAPKs, SRC-1 (Caenorhabditis elegans)


name: 1-naphthaleneacetamide + H2O <=> 1-naphthaleneacetate + NH4(+)


name: Ubiquitinated Orc1 enters the cytosol (Rattus norvegicus)


name: HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane (Canis familiaris)


name: DNA polymerase epsilon binds at the origin (Saccharomyces cerevisiae)


name: G alpha (z) inhibits adenylate cyclase (Dictyostelium discoideum)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-seryl-[protein] + UDP


name: H2O + hypoxanthine + NAD(+) = H(+) + NADH + xanthine


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Sus scrofa)


name: CCND1 recruits HDAC4 to RUNX3 (Sus scrofa)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)


name: D-aspartate(out) + H(+)(out) + K(+)(in) + 3 Na(+)(out) = D-aspartate(in) + H(+)(in) + K(+)(out) + 3 Na(+)(in)


name: CHUK, IKBKB phosphorylate CYLD at S418 (Sus scrofa)


name: O2 + pyridoxine 5'-phosphate <=> H2O2 + pyridoxal 5'-phosphate


name: H(+)(in) + L-lyxopyranose(in) <=> H(+)(out) + L-lyxopyranose(out)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Mus musculus)


name: L-dihomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-5-(methylsulfanyl)pentanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP (Homo sapiens)


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Gallus gallus)


name: putrescine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + S-methyl-5'-thioadenosine + spermidine


name: ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)


name: Formation of dehydro-hydroxylysino-norleucine cross-links (Danio rerio)


name: Release of SMAC (DIABLO) from mitochondria (Danio rerio)


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Caenorhabditis elegans)


name: SCF-beta-TrCP ubiquitinylates IkB (Canis familiaris)


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Rattus norvegicus)


name: 2 H(+) + hexadecanoyl-CoA + malonyl-CoA + methylmalonyl-CoA <=> 4-hydroxy-5-methyl-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA


name: Methylthio-ribose-P = Methylthio-ribulose-P (Canis familiaris)


name: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-nonadioyl-sn-glycero-3-phosphocholine


name: TP53 binds the FANCC gene (Homo sapiens)


name: an N-acyleicosasphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O => 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)


name: (2R)-3-sulfolactate + NAD(+) = 3-sulfopyruvate + H(+) + NADH


name: PIAS4 SUMOylates VDR with SUMO2 (Sus scrofa)


name: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine <=> H(+) + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine


name: Regorafenib-resistant PDGFR mutants don't bind regorafenib (Homo sapiens)


name: Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)


name: Oxidative damage to the AP site (Sus scrofa)


name: trans-Golgi Network Lysosomal Vesicle Scission (Gallus gallus)


name: (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H(+) + NADPH => (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + NADP(+)


name: HTR1A binds HTR1A agonists (Canis familiaris)


name: 2 glutathione + NAD(+) = glutathione disulfide + H(+) + NADH


name: PGM2:Mg2+ isomerises R1P to R5P (Sus scrofa)


name: DEK binds TFAP2A homodimers (Canis familiaris)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate <=> benzyl isothiocyanate + sulfate


name: 5-amino-2-oxopentanoate + L-alanine => L-ornithine + pyruvate


name: TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4  (Gallus gallus)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Xenopus tropicalis)


name: Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants (Homo sapiens)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Xenopus tropicalis)


name: solute:inorganic anion antiporter activity


name: 4-hydroxybutanoate + NAD(+) <=> H(+) + NADH + succinate semialdehyde


name: CMBL hydrolyses OM to OLMS (Danio rerio)


name: (2S,3S)-2-methylcitrate + CoA + H(+) => H2O + oxaloacetate + propanoyl-CoA


name: Phosphorylation of COP1 at Ser-387  by ATM (Bos taurus)


name: dodecanal + H2O + O2 => dodecanoate + H(+) + H2O2


name: RHOB binds effectors on endosomes (Homo sapiens)


name: PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)


name: abscisic acid glucose ester beta-glucosidase activity


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Canis familiaris)


name: indole-3-pyruvate + S-adenosyl-L-methionine = (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + S-adenosyl-L-homocysteine


name: CBLL1 ubiqutinates the InlA-bound CDH1 complex (Homo sapiens)


name: 1D-myo-inositol hexakisphosphate + ADP + H(+) => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Homo sapiens)


name: adenosine(34) in tRNA + H(+) + H2O => inosine(34) in tRNA + NH4(+)


name: O2 + 2 reduced coenzyme F420-(gamma-L-Glu)(n) = 2 H(+) + 2 H2O + 2 oxidized coenzyme F420-(gamma-L-Glu)(n)


name: CYP27A1 27-hydroxylates CHOL (Mus musculus)


name: Recognition of AAUAAA sequence by CPSF (Caenorhabditis elegans)


name: CDH11 canonical mRNA is translated into CDH11 canonical protein isoform (Homo sapiens)


name: WNT-dependent phosphorylation of DVL (Homo sapiens)


name: GST dimers conjugate GSH with cytosolic substrates (Mus musculus)


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Gallus gallus)


name: (-)-geosmin => (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + H2O


name: 2-hydroxyoctadecanoate + O2 <=> 2-oxooctadecanoate + H2O2


name: malonyl-CoA + S-adenosyl-L-methionine => malonyl-CoA methyl ester + S-adenosyl-L-homocysteine


name: tBID activates BAK protein (Canis familiaris)


name: NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) (Homo sapiens)


name: factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) (Bos taurus)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Drosophila melanogaster)


name: (+)-2-epi-prezizaene + diphosphate => (2Z,6E)-farnesyl diphosphate


name: Transport (influx) of bile salts and acids by OATP-A (Rattus norvegicus)


name: 4 H(+) + 4 malonyl-CoA <=> (3,5-dihydroxyphenyl)acetyl-CoA + 4 CO2 + 3 CoA + H2O


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Drosophila melanogaster)


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Mus musculus)


name: H(+) + NADPH + yaequinolone D <=> H2O + NADP(+) + penigequinolone A


name: RAC3 GAPs stimulate RAC3 GTPase activity (Danio rerio)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Bos taurus)


name: phosphoenolpyruvate + ADP => pyruvate + ATP (Sus scrofa)


name: dihydrochelirubine + NADP(+) <=> chelirubine + NADPH


name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 (Schizosaccharomyces pombe)


name: Loss of SAR1B GTPase (Dictyostelium discoideum)


name: 4-aminobenzoate + H(+) + pyruvate => 4-amino-4-deoxychorismate


name: The 60S subunit joins the translation initiation complex  (Drosophila melanogaster)


name: [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] <=> [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]


name: SLC26A3,6 exchange Cl- for HCO3- (Mus musculus)


name: Cation influx mediated by TRPC3/6/7 (Gallus gallus)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Saccharomyces cerevisiae)


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Canis familiaris)


name: The phagophore extends from the PIP3-enriched structure (Gallus gallus)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Homo sapiens)


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) <=> 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: PKA phosphorylates MAPKAPK5 (Rattus norvegicus)


name: PHGDH tetramer dehydrogenates 3PG (Canis familiaris)


name: NAD-dependent protein decrotonylase activity


name: H2O + N(6)-(2E)-butenoyl-L-lysyl-[protein] + NAD(+) = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: CHOL translocates from cytosol to mitochondrial intermembrane space (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + presilphiperfolan-8beta-ol


name: CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation (Homo sapiens)


name: CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)


name: 2 D-sedoheptulose 7-phosphate <=> D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O => a 5'-end 5'-monophospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H(+)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) => 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH


name: Dissociation of p-Y427-SHC1 from insulin receptor (Rattus norvegicus)


name: Ade-Rib binds AODORA2A and NTRK1,2 (Homo sapiens)


name: p-S115 MAPKAPK5 translocates to the cytosol (Danio rerio)


name: 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine => 7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA


name: MTTP lipidates APOB-100, forming a pre-VLDL (Bos taurus)


name: p-Y705,S727 STAT3 is acetylated (Canis familiaris)


name: RCHY1 monoubiquitinates POLH (Danio rerio)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Sus scrofa)


name: TP53 family members bind PPP1R13B or TP53BP2 (Homo sapiens)


name: 3-oxobutanoyl-[ACP] + acetyl-[ACP] + H2O => (3S)-hydroxy-3-methylglutaryl-[ACP] + H(+) + holo-[ACP]


name: Envoplakin binds periplakin (Homo sapiens)


name: Relaxin receptor 2 binds relaxin 2 and INSL3 (Sus scrofa)


name: SAR1 Activation And Membrane Binding (Bos taurus)


name: HSPA8 transports unfolded substrate to lysosomal lumen for degradation (Homo sapiens)


name: KCTD1 binds TFAP2 homo- and heterodimers (Rattus norvegicus)


name: Activated NTRK3 promotes SRC autophosphorylation (Bos taurus)


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Rattus norvegicus)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Bos taurus)


name: beta-alanyl-[peptidyl-carrier protein] + dopamine = beta-alanyl-dopamine + H(+) + holo-[peptidyl-carrier protein]


name: FMO3:FAD N-oxidises TMA to TMAO (Canis familiaris)


name: The anterograde IFT train dissociates (Sus scrofa)


name: 2,3-dioxo-L-gulonate => H2O + L-dehydroascorbate


name: cysteine-type endopeptidase inhibitor activity involved in apoptotic process


name: epiandrosterone 3-beta-D-glucoside + H(+) + UDP => 3beta-hydroxy-5alpha-androstan-17-one + UDP-alpha-D-glucose


name: Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Drosophila melanogaster)


name: alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SRC family kinases phosphorylate ERBB2 (Rattus norvegicus)


name: Activation of linoleic acid to linoleoyl-CoA (Canis familiaris)


name: 2 Fe(II)-[cytochrome c] + H(+) + NADP(+) => 2 Fe(III)-[cytochrome c] + NADPH


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Bos taurus)


name: RAP1A exchanges GDP for GTP (Bos taurus)


name: a fatty acyl-CoA + sphing-4-enine => an N-acylsphing-4-enine + CoA + H(+)


name: FYN autophosphorylates (Caenorhabditis elegans)


name: HTRA2 degrades APP (Amyloid-beta precursor protein) (Sus scrofa)


name: butanoyl-CoA + L-seryl-[protein] <=> CoA + O-butanoyl-L-seryl-[protein]


name: adenosine(1914)/adenosine(1915) in 18S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1914)/N(6)-dimethyladenosine(1915) in 18S rRNA + 4 S-adenosyl-L-homocysteine


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 1-O-methyl-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: LHPP:Mg2+ dimer hydrolyses PPi (Mus musculus)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Rattus norvegicus)


name: 16alpha,17beta-estriol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 16alpha,17beta-estriol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate


name: Activated protein C is released from PROCR (Mus musculus)


name: fusidate(in) + H(+)(out) => fusidate(out) + H(+)(in)


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Bos taurus)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Bos taurus)


name: IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Xenopus tropicalis)


name: (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O = bisdemethoxycurcumin + CO2 + 2 CoA


name: VMAT1/2 can mediate the transport of biogenic amines (Schizosaccharomyces pombe)


name: D-mannitol(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannitol 1-phosphate(in) + L-histidyl-[protein]


name: Somatostatin receptors bind somatostatin and cortistatin (Homo sapiens)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Sus scrofa)


name: beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-R + H(+) + UDP => an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Danio rerio)


name: IRAK4-activated IRAK1 autophosphorylates (Canis familiaris)


name: POLI incorporates dNMP opposite to damaged DNA base (Danio rerio)


name: Association of Emi1 with Cdh1 (Xenopus tropicalis)


name: 2 4-sulfanylbutanoate + NAD(+) => 4,4'-disulfanyldibutanoate + H(+) + NADH


name: XDH dehydrogenates hypoxanthine to form xanthine (Canis familiaris)


name: Loss of C-Nap-1 from centrosomes (Canis familiaris)


name: (E)-non-2-enoate + 2 H(+) + NADPH => (E)-non-2-enal + H2O + NADP(+)


name: acetyl-[ACP] + H(+) + malonyl-[ACP] <=> 3-oxobutanoyl-[ACP] + CO2 + holo-[ACP]


name: ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA (Sus scrofa)


name: high-affinity glucose:proton symporter activity


name: L-arginine(out) + L-ornithine(in) <=> L-arginine(in) + L-ornithine(out)


name: N-acetylation of serotonin (Mus musculus)


name: Expression of TUT4 in the embryo (Homo sapiens)


name: 7-carboxymellein + ATP + L-phenylalanine = ADP + H(+) + ochratoxin B + phosphate


name: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)


name: E2F6 binds the PRC1 complex (Sus scrofa)


name: A + all-trans-phytofluene <=> AH2 + all-trans-zeta-carotene


name: 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol


name: 4-hydroxybenzoate + H(+) + NADH + O2 => 3,4-dihydroxybenzoate + H2O + NAD(+)


name: aclacinomycin A + O2 = aclacinomycin Y + H2O2


name: glycerol 2-phosphate + H2O <=> glycerol + phosphate


name: Activation of Cdc42 by pVav1 (Mus musculus)


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Dictyostelium discoideum)


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> (Z)-gamma-bisabolene + diphosphate


name: chloride-activated potassium channel activity


name: SALMs 1-3 bind to PSD-95 family members (Xenopus tropicalis)


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Canis familiaris)


name: beta-dihydromenaquinone-9 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + omega-hydroxy-beta-dihydromenaquinone-9 + 2 oxidized [2Fe-2S]-[ferredoxin]


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Bos taurus)


name: N-tetradecanoyl-(2S)-hydroxyglycine <=> glyoxylate + tetradecamide


name: N(alpha)-methyl-L-histidine + S-adenosyl-L-methionine => H(+) + N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-homocysteine


name: gypsogenin + O2 + reduced [NADPH--hemoprotein reductase] <=> gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ent-copalyl diphosphate => diphosphate + ent-cassa-12,15-diene


name: 1,3-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-glycerol => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol


name: GLI:SUFU dissociates (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> (R)-nephthenol + diphosphate


name: Caspase-9 binds DCC:DIP13alpha complex (Homo sapiens)


name: (R)-propane-1,2-diol + NAD(+) => (R)-lactaldehyde + H(+) + NADH


name: L-fucose(out) + 2 Na(+)(out) <=> L-fucose(in) + 2 Na(+)(in)


name: 1D-myo-inositol 1,3,4-trisphosphate + H2O <=> 1D-myo-inositol 1,3-bisphosphate + phosphate


name: Defective AMN does not transport GIF:Cbl (Homo sapiens)


name: KALRN exchanges GTP for GDP on RAC1, activating it (Gallus gallus)


name: Autophosphorylation of SRC (Danio rerio)


name: myo-inositol + S-adenosyl-L-methionine <=> 1D-4-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycero-3-phosphate + an N-acylethanolamine + H(+) => H2O + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: H2O + O2 + spermine <=> H2O2 + NH4(+) + spermine monoaldehyde


name: [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin] => [thioredoxin]-disulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: beta-D-Glc-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP => N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose


name: OCT2 mediates tubular uptake of organic cations in the kidney (Drosophila melanogaster)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 3-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Dictyostelium discoideum)


name: Spermine  => N-acetylated spermine (Rattus norvegicus)


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Caenorhabditis elegans)


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Sus scrofa)


name: DEK binds TFAP2A homodimers (Xenopus tropicalis)


name: D-kanosamine 6-phosphate + H2O <=> kanosamine + phosphate


name: 3-[(R)-glyceryl]-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin => GMP + H(+) + oxidized 3PG-factor420-0


name: acetyl-CoA + N-terminal glycyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetylglycyl-[protein]


name: Binding of ATP to P2X receptors (Xenopus tropicalis)


name: PGH2 is isomerised to PGD2 by PTGDS (Xenopus tropicalis)


name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Sus scrofa)


name: beta-ketoacyl-acyl-carrier-protein synthase III activity


name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs (Homo sapiens)


name: 3',5'-cyclic GMP(in) = 3',5'-cyclic GMP(out)


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Mus musculus)


name: (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + NADH


name: Multiphospho-CERT1-2 binds PPM1L, VAPA/B (Danio rerio)


name: a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+) + L-tyrosine => a 5'-end L-tyrosylphosphate-2'-deoxynucleoside-DNA + H2O


name: cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (25S)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Phosphorylation of PKC theta (Drosophila melanogaster)


name: H2O + L-fucono-1,5-lactone = H(+) + L-fuconate


name: Necl-2:Nectin 3 trans heterodimer interaction (Bos taurus)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Sus scrofa)


name: CFTR F508del is degraded by the 26S proteasome (Homo sapiens)


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Homo sapiens)


name: ERK1/2/5 activate RSK1/2/3 (Homo sapiens)


name: 2-hydroxy-3-methylbutanoyl-CoA + CO2 + succinate => 2-oxoglutarate + 3-methylbutanoyl-CoA + O2


name: (3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl-[ACP] + AH2 + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine <=> 6-[(3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl]-2,4-dihydroxy-3-methylbenzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP] + S-adenosyl-L-homocysteine


name: 4-hydroxybenzoate + all-trans-decaprenyl diphosphate = 4-hydroxy-3-all-trans-decaprenylbenzoate + diphosphate


name: trans-2-enoyl-CoA reductase (NADPH) activity


name: ISGylation of E2 conjugating enzymes (Bos taurus)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA


name: 3-phenylpropanoate + H(+) + NADH + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)


name: JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Canis familiaris)


name: PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane (Homo sapiens)


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Homo sapiens)


name: MK2 phosphorylates BRF1 (Drosophila melanogaster)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA => (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + malonyl-CoA


name: mangiferin + O2 => 3'-dehydromangiferin + H2O2


name: HMGCR dimer reduces bHMG-CoA to MVA (Sus scrofa)


name: MECP2 binds the STAT5A gene (Homo sapiens)


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Homo sapiens)


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: (9Z)-octadecenoyl-CoA + 1,2-dihexanoylglycerol => 1,2-dihexanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 <=> (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate


name: AGRN binds Alpha-dystroglycan (Homo sapiens)


name: 3alpha-hydroxy-5beta-pregnan-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Gallus gallus)


name: TXLNA (IL14) binds syntaxin1A (Drosophila melanogaster)


name: NAALADases hydrolyse NAAG (Saccharomyces cerevisiae)


name: CBL monoubiquitinates activated MET (Mus musculus)


name: RHOF GAPs stimulate RHOF GTPase activity (Danio rerio)


name: Furin cleaves pro-protein Z to protein Z (Bos taurus)


name: SUMOylation of RARA with SUMO2 (Gallus gallus)


name: ATP + L-aspartate + NH4(+) <=> ADP + H(+) + L-asparagine + phosphate


name: T2Rs bind bitter-tasting compounds (Mus musculus)


name: PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Gallus gallus)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Dictyostelium discoideum)


name: L-lysine + NAD(+) <=> 2 H(+) + L-1-piperideine-6-carboxylate + NADH + NH4(+)


name: fluoride transmembrane transporter activity


name: RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Rattus norvegicus)


name: IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Canis familiaris)


name: Superoxide reduces cytochrome c (Danio rerio)


name: an alditol + NADP(+) => an aldose + H(+) + NADPH


name: RNF20:RNF40 monoubiquitinates Histone H2B (Drosophila melanogaster)


name: Fe(III)-enterobactin + H(+) + 3 H2O = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + 2 N-(2,3-dihydroxybenzoyl)-L-serine


name: G beta-gamma complex and PIP3 recruit BTK to membrane (Canis familiaris)


name: 4-methylumbelliferone beta-D-glucuronate(in) + ATP + H2O => 4-methylumbelliferone beta-D-glucuronate(out) + ADP + H(+) + phosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho]-glycerol + CoA


name: (E)-pent-2-en-1-ol + NADP(+) = (E)-2-pentenal + H(+) + NADPH


name: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Homo sapiens)


name: REG3A binds bacterial phospholipids (Homo sapiens)


name: (3E,5Z)-tetradecadienoyl-CoA + H2O = (3E,5Z)-tetradecadienoate + CoA + H(+)


name: phenazine-1-carboxylate + S-adenosyl-L-methionine <=> 5-methyl-phenazine-1-carboxylate + S-adenosyl-L-homocysteine


name: glucagon-like peptide 1 receptor activity


name: bPIX exchanges GTP for GDP on RAC, activating it (Xenopus tropicalis)


name: Acyl Ghrelin and C-Ghrelin are secreted (Gallus gallus)


name: precorrin-2 + S-adenosyl-L-methionine = H(+) + precorrin-3A + S-adenosyl-L-homocysteine


name: Phosphorylation and activation of eIF4B by activated S6K1 (Sus scrofa)


name: Activated JNKs phosphorylate c-JUN (Saccharomyces cerevisiae)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Sus scrofa)


name: (9Z)-heptadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + heptadecanoyl-CoA + O2


name: 24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: all-trans-zeaxanthin + O2 = (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone


name: PXLP-K56-SRR dimer deaminates L-Ser (Sus scrofa)


name: 2'-hydroxy-2,3-dihydrodaidzein + NADP(+) = 2'-hydroxydaidzein + 2 H(+) + NADPH


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Caenorhabditis elegans)


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Gallus gallus)


name: ZFP36 (TTP) recruits RNA degradation activities (Rattus norvegicus)


name: (2S)-2-phospholactate + GTP + H(+) => (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate


name: catechol + CO2 + NADH => (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: nucleoside triphosphate adenylate kinase activity


name: D-allose + L-lysyl-[protein] = H2O + N(6)-(D-psicosyl)-L-lysyl-[protein]


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Xenopus tropicalis)


name: Inactivation of Rho-GTP by p190RhoGAP (Danio rerio)


name: benzoyl-CoA + H2O + oxidized 2[4Fe-4S]-[ferredoxin] => 4-hydroxybenzoyl-CoA + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: Formation of RAD52 heptameric ring structure complexes (Homo sapiens)


name: carbamoyl phosphate + descarbamoylnovobiocin = novobiocin + phosphate


name: S-adenosyl-L-methionine + uridine(54) in tRNA <=> 5-methyluridine(54) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Bos taurus)


name: 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+) => bis(2-ethylhexyl)phthalate + H2O


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Mus musculus)


name: RAC1 GDIs block activation of RAC1 (Danio rerio)


name: 5 (S)-methylmalonyl-CoA + a medium-chain fatty acyl-CoA + 32 H(+) + 5 malonyl-CoA + 22 NADPH => a mycoketide-CoA + 10 CO2 + 10 CoA + 11 H2O + 22 NADP(+)


name: GTP + S-adenosyl-L-methionine = N(7)-methyl-GTP + S-adenosyl-L-homocysteine


name: (9Z,11E)-octadecadienoate + H2O = 10-hydroxy-(11E)-octadecenoate


name: SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP (Caenorhabditis elegans)


name: 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine <=> 8,12-diethyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: MAPKAPK5 phosphorylates KALRN (Gallus gallus)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Bos taurus)


name: 3'-phosphoadenylyl sulfate + L-tyrosyl-[protein] = adenosine 3',5'-bisphosphate + H(+) + O-sulfo-L-tyrosine-[protein]


name: JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Homo sapiens)


name: DHODH:FMN binds DHODH inhibitors (Canis familiaris)


name: inulobiose => alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride + H2O


name: (3S)-hydroxytetradecanedioyl-CoA + NAD(+) <=> 3-oxotetradecanedioyl-CoA + H(+) + NADH


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + dodecanoyl-CoA => 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: N-(8'-hydroxygeranyl)-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + N-(8'-oxogeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase]


name: CYP26C1 4-hydroxylates 9cRA (Canis familiaris)


name: Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)


name: HMGB1 binds LPS (Drosophila melanogaster)


name: LRTOMT transfers Met to DA, forming 3MT (Mus musculus)


name: SMURF2 ubiquitinates SMAD2 (Rattus norvegicus)


name: a 5'-end NAD(+)-phospho-ribonucleoside in snoRNA + H2O <=> a 5'-end phospho-ribonucleoside in snoRNA + H(+) + NAD(+)


name: α1-antagonists bind ADRA1A,B,D (Bos taurus)


name: ethionamide S-oxide + H2O + NADP(+) => ethionamide + H(+) + NADPH + O2


name: indole-3-pyruvate + L-kynurenine => H2O + kynurenate + L-tryptophan


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) => (6R)-L-erythro-6,7-dihydrobiopterin + H(+) + NADPH


name: acetate(out) + Na(+)(out) => acetate(in) + Na(+)(in)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:SOS1 (Homo sapiens)


name: 2 Na(+)(out) + pyruvate(out) <=> 2 Na(+)(in) + pyruvate(in)


name: ATP + CoA + tetracosanoate = AMP + diphosphate + tetracosanoyl-CoA


name: Receptor CCR9  binds CCL25 ligand (Rattus norvegicus)


name: BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Xenopus tropicalis)


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Gallus gallus)


name: SUMOylation of NPM1 with SUMO1 (Gallus gallus)


name: ATP + H2O + L-cysteine(in) <=> ADP + H(+) + L-cysteine(out) + phosphate


name: Latent TGF-beta-3 binds integrins (Danio rerio)


name: Acetylcholine binds Muscarinic Acetylcholine Receptor M3 (Homo sapiens)


name: ERBB4 forms heterodimers with EGFR (Gallus gallus)


name: a 2-acyl-sn-glycerol 3-phosphate + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphate + CoA


name: 10-deoxymethynolide + dTDP-alpha-D-desosamine = 10-deoxymethymycin + dTDP + H(+)


name: 2-oxoglutarate + clavatol + O2 <=> CO2 + hydroxyclavatol + succinate


name: Insertion of correct bases opposite the lesion by POLH (Plasmodium falciparum)


name: Tachykinin receptor 1 (NK1) binds to substance P (Homo sapiens)


name: 1-O-decyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-decyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: a fatty acyl-AMP + diphosphate => a fatty acid + ATP + H(+)


name: (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + NADPH => (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Plasmodium falciparum)


name: 2-hydroxytoluene + H2O + NAD(+) => H(+) + NADH + O2 + toluene


name: (2E)-decenoate + ATP + holo-[ACP] => (2E)-decenoyl-[ACP] + AMP + diphosphate


name: AMP(in) + diphosphate(in) + docosanoyl-CoA(in) + H(+)(in) => ATP(in) + CoA(in) + docosanoate(out) + H(+)(out)


name: OSM binds LIFR:JAKs,OSMR:JAKs (Canis familiaris)


name: Release of docked dopamine loaded synaptic vesicle (Caenorhabditis elegans)


name: L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] => 2 H(+) + H2O + N-hydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]


name: (E,E)-piperoyl-CoA + piperidine => CoA + H(+) + piperine


name: RHOQ GEFs activate RHOQ (Schizosaccharomyces pombe)


name: CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] => dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: putrescine + S-adenosyl-L-methionine => H(+) + N-methylputrescine + S-adenosyl-L-homocysteine


name: ADP + H(+) + sucrose => ADP-alpha-D-glucose + D-fructose


name: ITCH gene expression is stimulated by RUNX1 and YAP1 (Homo sapiens)


name: BRCA1:BARD1 heterodimer autoubiquitinates (Canis familiaris)


name: carbofuran + H(+) + H2O => 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol + CO2 + methylamine


name: (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(12Z,15Z,18Z,21Z)-tetracosatetraenoyl-CoA + CO2 + CoA


name: 22-hydroxydocosanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 22-oxodocosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADH + O2 + salicylate => 2,3-dihydroxybenzoate + H2O + NAD(+)


name: 8-oxo-dAMP + H(+) + phosphate => 8-oxo-dADP + H2O


name: TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Danio rerio)


name: NADP(+) + UDP-N-acetyl-alpha-D-quinovosamine => H(+) + NADPH + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose


name: dihydroalstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine


name: 6-hydroxyphenazine-1-carboxylate + 2 H(+) + NADH + O2 => 1,6-dihydroxyphenazine + CO2 + H2O + NAD(+)


name: EGF-TM7 receptors bind chondroitin sulphate (Bos taurus)


name: 2 Fe(III)-[cytochrome c] + H2O + sulfite = 2 Fe(II)-[cytochrome c] + 2 H(+) + sulfate


name: PHF8 demethylates MeK21-histone H4 (Mus musculus)


name: 2 Fe(III)-[cytochrome b5] + NADPH <=> 2 Fe(II)-[cytochrome b5] + H(+) + NADP(+)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Homo sapiens)


name: GPLD1 hydrolyses GPI-anchors from proteins (Saccharomyces cerevisiae)


name: ORC6 is phosphorylated on T195 (Schizosaccharomyces pombe)


name: The PIDDosome activates CASP2 (Mus musculus)


name: Activated FGFR3 point and translocation mutants bind PLCG1 (Homo sapiens)


name: MME:Zn2+ hydrolyses AGT(34-43) (Rattus norvegicus)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Danio rerio)


name: PXLP-K56-SRR dimer deaminates D-Ser (Mus musculus)


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Homo sapiens)


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Homo sapiens)


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Bos taurus)


name: 2'-hydroxy-2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2',2'-dihydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: AP-2 directly binds some endocytic cargo (Mus musculus)


name: H2O + methyl (indol-3-yl)acetate <=> (indol-3-yl)acetate + H(+) + methanol


name: Growth hormone receptor binds JAK2 (Homo sapiens)


name: FGFR4 binds HS:KLB:FGF19 (Xenopus tropicalis)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + ATP = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Formation of lysino-5-ketonorleucine cross-links (Rattus norvegicus)


name: Phosphorylation of MEF2 proteins by p38 (Schizosaccharomyces pombe)


name: L-glutamine(in) + L-valine(out) + Na(+)(out) = L-glutamine(out) + L-valine(in) + Na(+)(in)


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 => (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2


name: LHPP:Mg2+ dimer hydrolyses PPi (Bos taurus)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Dictyostelium discoideum)


name: 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADP(+)


name: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = deacetoxyvindoline + H(+) + S-adenosyl-L-homocysteine


name: an N-acylethanolamine phosphate + H2O = an N-acylethanolamine + phosphate


name: 4-O-(beta-D-glucosyl)-4-trans-sinapoyl aldehyde + H(+) + UDP => (E)-sinapaldehyde + UDP-alpha-D-glucose


name: (11Z)-eicosenoate + NH4(+) => (11Z)-eicosenamide + H2O


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)


name: a 3-dehydro-D-guloside + H(+) + NADH => a D-guloside + NAD(+)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Canis familiaris)


name: O2 + torulene <=> 3-methyl-2-butenal + 4'-apo-beta-carotenal


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a 1-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: LGI2 binds ADAM22,23 (Xenopus tropicalis)


name: a quinone + shikimate = 3-dehydroshikimate + a quinol


name: (6Z,9Z,12Z)-octadecatrienoate + O2 <=> 10-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Gallus gallus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Mus musculus)


name: L-tyrosyl-[protein] + NAD(+) => H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein]


name: MAP2K2 phosphorylates MAPK1 (Canis familiaris)


name: (2Z,6Z)-farnesyl diphosphate <=> alpha-acoradiene + diphosphate


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Xenopus tropicalis)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Xenopus tropicalis)


name: Enzyme-bound ATP is released (Sus scrofa)


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Bos taurus)


name: 3 AH2 + ATP + H2O + Ni-sirohydrochlorin a,c-diamide <=> 15,17(3)-seco-F430-17(3)-acid + 3 A + ADP + phosphate


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA


name: a 2'-O-methylribonucleotide in RNA + H(+) + S-adenosyl-L-homocysteine => a ribonucleotide in RNA + S-adenosyl-L-methionine


name: CoA + O-acetyl-L-threonyl-[protein] => acetyl-CoA + L-threonyl-[protein]


name: Isomerization of GlcNAc6P to GlcNAc1P (Schizosaccharomyces pombe)


name: alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP-alpha-D-galactofuranose => beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + H(+) + UDP


name: IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor (Homo sapiens)


name: 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-diene-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA


name: H(+) + NADH + O2 + protoviolaceinate => H2O + NAD(+) + violaceinate


name: PPP5C dephosphorylates TP53BP1 (Mus musculus)


name: nicotinate(out) + urate(in) => nicotinate(in) + urate(out)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Rattus norvegicus)


name: 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oate + ATP + CoA <=> 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oyl-CoA + AMP + diphosphate


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Canis familiaris)


name: 4-nitrotoluene + NADH + O2 = 4-methylcatechol + NAD(+) + nitrite


name: Movement of clathrin coated vesicles into early endosome (Drosophila melanogaster)


name: Release of 40S and 60S subunits from the 80S ribosome  (Sus scrofa)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Rattus norvegicus)


name: CoA + O-decanoyl-L-seryl-[protein] => decanoyl-CoA + L-seryl-[protein]


name: nucleoside oxidase (hydrogen peroxide-forming) activity


name: beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Mus musculus)


name: SYK autophosphorylates (Rattus norvegicus)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Homo sapiens)


name: 7-hydroxyquinolin-2(1H)-one + AH2 => A + H2O + quinolin-7-ol


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC22A13 transports NCA from extracellular region to cytosol (Canis familiaris)


name: JAK1 binds IL4R in IL4-bound IL4R1 (Sus scrofa)


name: alcohol transmembrane transporter activity


name: MVD decarboxylates MVA5PP to IPPP (Gallus gallus)


name: 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + S-adenosyl-L-methionine => 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP => 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: Formation of Elongin complex (Mus musculus)


name: 1,7-dimethylxanthine + S-adenosyl-L-methionine => caffeine + H(+) + S-adenosyl-L-homocysteine


name: 3xPPCDC:3FMN decarboxylates PPC (Caenorhabditis elegans)


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Bos taurus)


name: SLP-76 stimulates PLC gamma 2 (Drosophila melanogaster)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + H(+) + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] = a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + L-histidyl-[RNA ligase]


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Danio rerio)


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Rattus norvegicus)


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Danio rerio)


name: 2,5-dioxopentanoate + H2O => 2-dehydro-3-deoxy-D-arabinonate


name: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate


name: glycyl-tRNA(Ala) + H2O => glycine + H(+) + tRNA(Ala)


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-organyl-2-lyso-sn-glycero-3-phospholipid <=> 1-O-alkyl-sn-glycero-3-phosphocholine + a 1-organyl-2-acetyl-sn-glycero-3-phospholipid


name: Caspase-mediated cleavage of Lamin A (Bos taurus)


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Homo sapiens)


name: STING ubiquitination by TRIM32 or TRIM56 (Mus musculus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA


name: Resumption of elongation after recovery from pausing (Caenorhabditis elegans)


name: Intrinsic nucleotide exchange on RAS (Canis familiaris)


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)


name: N(omega)-hydroxy-L-arginine => guanidine + L-glutamate 5-semialdehyde


name: 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine => L-lysyl-[protein] + 3 S-adenosyl-L-methionine


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Canis familiaris)


name: PalmS-ESRs:CAVs translocate to plasma membrane (Xenopus tropicalis)


name: 2-hydroxy-2-(4-hydroxyphenyl)acetate + H(+) = 4-hydroxybenzyl alcohol + CO2


name: PKC autophosphorylates (Rattus norvegicus)


name: PLK2 phosphorylates CENPJ (Mus musculus)


name: NRXNs bind CASK:Protein 4.1 (Mus musculus)


name: ALDH4A1 oxidises L-GluSS to Glu (Canis familiaris)


name: ABCE1 binds RNASEL, inhibiting it (Xenopus tropicalis)


name: H(+) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Homo sapiens)


name: Transport of Antigen peptide in to ER (Homo sapiens)


name: ASA- (GI) translocates from cytosol to extracellular region (Homo sapiens)


name: ERK1/2-activated AP1 complex binds KDM6B promoter (Homo sapiens)


name: guanosine(37) in tRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine


name: Intrinsic nucleotide exchange on RAS (Danio rerio)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Homo sapiens)


name: CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) (Sus scrofa)


name: a guaiacol + H(+) + S-adenosyl-L-homocysteine => a catechol + S-adenosyl-L-methionine


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Drosophila melanogaster)


name: tRNA-guanosine(34) queuine transglycosylase activity


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Bos taurus)


name: Interleukin-16 is secreted (Gallus gallus)


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Xenopus tropicalis)


name: GSDMD forms ring‐shaped oligomers  (Homo sapiens)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Xenopus tropicalis)


name: acetyl-CoA + beta-D-glucose = 6-O-acetyl-beta-D-glucose + CoA


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Xenopus tropicalis)


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Danio rerio)


name: IMPDH tetramers binds IMPDH inhibitors (Rattus norvegicus)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Bos taurus)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Dictyostelium discoideum)


name: (E)-sinapate + UDP-alpha-D-glucose <=> 4-O-(beta-D-glucosyl)-trans-sinapate + H(+) + UDP


name: formyl-CoA + oxalate <=> formate + oxalyl-CoA


name: H2O + L-methionine => 2-oxobutanoate + methanethiol + NH4(+)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Xenopus tropicalis)


name: formate + N-terminal L-methionyl-[peptide] => H2O + N-terminal N-formyl-L-methionyl-[peptide]


name: AKT phosphorylates caspase-9 (Danio rerio)


name: Recruitment of HDAC1 by p130 (RBL2) (Sus scrofa)


name: SFN dimer binds CDK1 and CCNB1 (Xenopus tropicalis)


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Plasmodium falciparum)


name: Phosphorylation of cPLA2 by ERK-2 (Rattus norvegicus)


name: GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate <=> GDP + H(+) + methyl 8-{[alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc]oxy}nonanoate


name: (R)-nicotine + A + H2O => (R)-6-hydroxynicotine + AH2


name: (2R,3S)-piscidate + (E)-sinapoyl-CoA => cimicifugate J + CoA


name: TRAF6 is K63 poly-ubiquitinated (Rattus norvegicus)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Drosophila melanogaster)


name: (9Z)-hexadecenoyl-CoA + 3-oxosphinganine <=> CoA + H(+) + N-(9Z-hexadecenoyl)-3-oxosphinganine


name: alpha-D-mannose 1-phosphate + GDP + H(+) <=> GDP-alpha-D-mannose + phosphate


name: dehydroepiandrosterone 3-sulfate(in) + propanoate(out) <=> dehydroepiandrosterone 3-sulfate(out) + propanoate(in)


name: Formation of BRCA1-A complex at DNA DSBs (Gallus gallus)


name: 3-oxocyclopentanecarbonitrile + 2 H2O <=> 3-oxocyclopentanecarboxylate + NH4(+)


name: holo-[peptidyl-carrier protein] + L-cysteinyl-5'-AMP => AMP + H(+) + L-cysteinyl-[peptidyl-carrier protein]


name: Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Bos taurus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NAD(+)


name: Phosphorylated OPTN translocates to the nucleus (Rattus norvegicus)


name: CHIT1 hydrolyses CHIT to 3xADGP (Caenorhabditis elegans)


name: PIAS4 SUMOylates MDC1 (Rattus norvegicus)


name: H2O + N-acetyl-L-phenylalanine <=> acetate + L-phenylalanine


name: a globoside Forssman (d18:1(4E)) + H(+) + UDP => a globoside Gb4Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: p-Y420-FYN is phosphorylated on S21 (Danio rerio)


name: H(+) + L-rhamnonate => H2O + L-rhamnono-1,4-lactone


name: Formation of Cyclin E:Cdk2 complexes (Bos taurus)


name: IL1R1:IL1:IL1RAP binds MYD88 homodimer (Gallus gallus)


name: (R)-pantoate + ATP <=> (R)-4-phosphopantoate + ADP + H(+)


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Sus scrofa)


name: glycyl-L-asparagine + H2O = glycine + L-asparagine


name: p-Y701-STAT1 dimerizes (Rattus norvegicus)


name: 4-methyl-3-oxopentanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxy-4-methylpentanoyl-[ACP] + NADP(+)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Canis familiaris)


name: butanoyl-CoA + tyramine => CoA + H(+) + N-butanoyltyramine


name: p38 MAPK activation by VEGFR (Gallus gallus)


name: FGAM + ATP => AIR + ADP + Pi (Rattus norvegicus)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Xenopus tropicalis)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Danio rerio)


name: 2-oxoglutarate + O2 + pentalenolactone D => CO2 + H2O + pentalenolactone E + succinate


name: (2E,6E)-farnesyl diphosphate <=> african-3-ene + diphosphate


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: 2 Na(+)(out) + pyruvate(out) = 2 Na(+)(in) + pyruvate(in)


name: Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Sus scrofa)


name: BCMO1:Fe2+ cleaves betaC to atRAL (Xenopus tropicalis)


name: dATP + pyruvate <=> dADP + H(+) + phosphoenolpyruvate


name: FGR binds and phosphorylates LRP8 (Mus musculus)


name: Formation of MSH1:PMS2 Complex (Saccharomyces cerevisiae)


name: Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind GRB2:GAB1 (Homo sapiens)


name: ADP + H(+) + L-glutamine + phosphate => ATP + L-glutamate + NH4(+)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Danio rerio)


name: Autophosphorylation of insulin receptor (Homo sapiens)


name: H(+) + NADH + S-formylglutathione => NAD(+) + S-(hydroxymethyl)glutathione


name: 2-oxobutanoate + L-glutamine <=> (2S)-2-aminobutanoate + 2-oxoglutaramate


name: 2 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycero-3-phosphoethanolamine


name: an acyl-CoA + H(+) + malonyl-CoA <=> a 3-oxoacyl-CoA + CO2 + CoA


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Drosophila melanogaster)


name: CHSY1 transfers GalNAc to chondroitin (Sus scrofa)


name: ADP + H(+) + leukotriene C4(out) + phosphate => ATP + H2O + leukotriene C4(in)


name: guanidinoacetate + L-ornithine => glycine + L-arginine


name: 2-oxoglutarate(out) + urate(in) <=> 2-oxoglutarate(in) + urate(out)


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Drosophila melanogaster)


name: 4alpha-methylzymosterol + NADP(+) => 3-dehydro-4alpha-methylzymosterol + H(+) + NADPH


name: H(+) + N-tetracosanoylsphinganine + NADPH + O2 => H2O + N-(2-hydroxytetracosanoyl)-sphinganine + NADP(+)


name: 2 Na(+)(out) + tauronorcholate(out) <=> 2 Na(+)(in) + tauronorcholate(in)


name: L-histidyl-L-proline diketopiperazine(in) => L-histidyl-L-proline diketopiperazine(out)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Dictyostelium discoideum)


name: a dicarboxylate(in) + prostaglandin E2(out) => a dicarboxylate(out) + prostaglandin E2(in)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Homo sapiens)


name: SH2 domain of Src binds to the active receptor (Rattus norvegicus)


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) + phosphate => a 5'-end triphospho-(purine-ribonucleoside) in mRNA + H2O


name: protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity


name: n fibrin monomers -> fibrin multimer (Mus musculus)


name: P2Y2 receptor binds ATP and UTP (Mus musculus)


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Dictyostelium discoideum)


name: (2E)-geranyl diphosphate + 7 isopentenyl diphosphate <=> all-trans-nonaprenyl diphosphate + 7 diphosphate


name: HYKK phosphorylates 5HLYS (Homo sapiens)


name: C3G stimulates nucleotide exchange on Rap1 (Bos taurus)


name: chloride(out) + L-serine(out) + 2 Na(+)(out) <=> chloride(in) + L-serine(in) + 2 Na(+)(in)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: AcK-NFE2L2 binds the ABCF2 gene (Homo sapiens)


name: HJURP:CENPA complex localizes to the centromere (Rattus norvegicus)


name: misfolded CFTR is degraded by the 26S proteasome (Rattus norvegicus)


name: sphingolipid delta-8 desaturase activity


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Xenopus tropicalis)


name: 3-hydroxy-4-methylanthranilate + H(+) + S-adenosyl-L-homocysteine => 3-hydroxyanthranilate + S-adenosyl-L-methionine


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Schizosaccharomyces pombe)


name: Ligand-independent dimerization of PDGFR mutants (Homo sapiens)


name: Proteasome mediated degradation of PAK-2p34 (Homo sapiens)


name: palmitoleic acid delta 12 desaturase activity


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Xenopus tropicalis)


name: ADAMTS13 cleaves VWF multimer (Sus scrofa)


name: D-mannose(in) + H(+)(in) => D-mannose(out) + H(+)(out)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Mus musculus)


name: RUNX2 binds SMAD1 in the nucleus (Mus musculus)


name: Oxidation of cholesterol to 22beta-hydroxycholesterol (Xenopus tropicalis)


name: H(+) + keto-D-fructose + NADH <=> D-sorbitol + NAD(+)


name: Tenascins C, R, (X, N) bind lecticans (Homo sapiens)


name: N(5)-hydroxy-L-ornithine <=> (3S)-1,2-diazinane-3-carboxylate + H(+) + H2O


name: SLP-76 stimulates PLC gamma 2 (Plasmodium falciparum)


name: 3 2,3-dihydroxybenzoate + 6 ATP + 3 glycine + 3 L-threonine = 6 AMP + corynebactin + 6 diphosphate + 3 H(+) + 3 H2O


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Canis familiaris)


name: (2E)-geranyl diphosphate <=> (-)-beta-phellandrene + diphosphate


name: AFG3L2 binds mitochondrial matrix proteins (Canis familiaris)


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Drosophila melanogaster)


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Mus musculus)


name: Release of eIF4E from the inactive eIF4E:4E-BP complex  (Mus musculus)


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Rattus norvegicus)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Sus scrofa)


name: a carotenoid phi-end derivative + 2 AH2 => 2 A + a carotenoid beta-end derivative


name: RNA 2'-O-ribose methylation guide activity


name: B4GALTs transfer Gal to a branch of keratan (Danio rerio)


name: a 5-methylcytidine in 28S rRNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in 28S rRNA + S-adenosyl-L-methionine


name: lathosterol + NAD(+) => 5alpha-cholest-7-en-3-one + H(+) + NADH


name: a globoside Gb3Cer + H2O => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + D-galactose


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Homo sapiens)


name: Release of platelet secretory granule components (Xenopus tropicalis)


name: Release of CSK from SRC (Canis familiaris)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)


name: p62 links damaged mitochondria to LC3 (Mus musculus)


name: Thiosulfate can transfer its sulfur atom to glutathione (Xenopus tropicalis)


name: ERBB4 forms heterodimers with ERBB3 (Canis familiaris)


name: ADP + D-ribulose 1,5-bisphosphate + H(+) => ATP + D-ribulose 5-phosphate


name: IL7:IL7R:JAK1 binds IL2RG:JAK3 (Mus musculus)


name: (2R)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine => (2S,4R)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine


name: atROL binds RBP1 to form RBP1:atROL (Danio rerio)


name: H(+) + NADH + O2 + toluene => 4-methylphenol + H2O + NAD(+)


name: 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] (Homo sapiens)


name: H2O + L-glutamine + O2 = 2-oxoglutaramate + H2O2 + NH4(+)


name: H(+) + H2O + S-methyl-5'-thioadenosine = NH4(+) + S-methyl-5'-thioinosine


name: HAGH hydrolyses (R)-S-LGSH to GSH and LACT (Saccharomyces cerevisiae)


name: 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in single-stranded DNA + O2 => a 2'-deoxyadenosine in single-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Drosophila melanogaster)


name: OPN (osteopontin) degradation by MMP3, MMP7 (Bos taurus)


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: NEIL3 resolves abasic site-induced ICLs (Homo sapiens)


name: alpha-zingiberene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (1S,5R)-carveol + NAD(+) <=> (R)-carvone + H(+) + NADH


name: NT5E:Zn2+ hydrolyses NMN (Canis familiaris)


name: Activation of RAS by p-KIT bound SOS1 (Canis familiaris)


name: (4R)-hydroxysphinganine + octadecanoate => H2O + N-octadecanoyl-(4R)-hydroxysphinganine


name: glycerol + H(+) + sn-glycerol 3-phosphate => H2O + sn-glycero-3-phospho-(1'-rac-glycerol)


name: IL20 binds IL20RA:JAK1:IL20RB (Mus musculus)


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Danio rerio)


name: SeMet is converted to AdoSeMet by MAT (Bos taurus)


name: atROL binds RBP1 to form RBP1:atROL (Homo sapiens)


name: docosanedioate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 22-oxodocosanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Saccharomyces cerevisiae)


name: CMP(in) + CMP-N-acetyl-beta-neuraminate(out) => CMP(out) + CMP-N-acetyl-beta-neuraminate(in)


name: Expression of glutathione S-transferase alpha 2 (Homo sapiens)


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Plasmodium falciparum)


name: H(+)(out) + L-glutamate(out) + L-glutamine(in) + Na(+)(out) <=> H(+)(in) + L-glutamate(in) + L-glutamine(out) + Na(+)(in)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Sus scrofa)


name: C1-Inh binds and inactivates C1r, C1s (Rattus norvegicus)


name: (R)-pantoate + ATP + beta-alanine => (R)-pantothenate + AMP + diphosphate + H(+)


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Canis familiaris)


name: TOPORS SUMOylates SIN3A with SUMO1 (Dictyostelium discoideum)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Saccharomyces cerevisiae)


name: a N-(2-hydroxyacyl)sphing-4-enine + UDP-alpha-D-galactose = a 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphing-4-enine + H(+) + UDP


name: (S)-S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine <=> 3-O-acetylpapaveroxine + H(+) + S-adenosyl-L-homocysteine


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Sus scrofa)


name: H(+) + heptanoyl-CoA + malonyl-[ACP] => 3-oxononanoyl-[ACP] + CO2 + CoA


name: [5-(aminomethyl)-3-furyl]methyl phosphate + pyruvate => 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + L-alanine


name: 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine <=> H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate


name: pregnenolone + UDP-alpha-D-glucose => H(+) + pregnenolone 3-beta-D-glucoside + UDP


name: RTC binds SARS-CoV-2 genomic RNA complement (minus strand) (Homo sapiens)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Dictyostelium discoideum)


name: an S-prenyl-L-cysteine + H2O + O2 => a prenal + H2O2 + L-cysteine


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Sus scrofa)


name: 2-amino-4-hydroxypteridine + H(+) + H2O <=> 2,4-dihydroxypteridine + NH4(+)


name: a 3-oxo-Delta(4)-steroid + H(+) + NADPH => a 3-oxo-5alpha-steroid + NADP(+)


name: H(+)(in) + L-alanyl-D-glutamate(in) => H(+)(out) + L-alanyl-D-glutamate(out)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 <=> (5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoate + A + H2O


name: REV1 binds AP-dsDNA (Plasmodium falciparum)


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Gallus gallus)


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Rattus norvegicus)


name: Regeneration of eEF1A:GTP by eEF1B activity (Dictyostelium discoideum)


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Homo sapiens)


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Drosophila melanogaster)


name: PIAS1 SUMOylates SATB1 with SUMO1 (Gallus gallus)


name: (2S)-2-aminobutan-1-ol + H2O + NAD(+) <=> 1-hydroxy-2-butanone + H(+) + NADH + NH4(+)


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Bos taurus)


name: a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O


name: Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane (Homo sapiens)


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Bos taurus)


name: L-threitol + NAD(+) => H(+) + L-erythrulose + NADH


name: p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)


name: RHOU binds effectors at the plasma membrane (Mus musculus)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + ATP + H2O => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + ADP + H(+) + phosphate


name: E1 mediated ubiquitin activation (Xenopus tropicalis)


name: [thioredoxin]-dithiol + tert-butyl hydroperoxide => [thioredoxin]-disulfide + H2O + tert-butanol


name: nicotinamide riboside transmembrane transporter activity


name: beta-nicotinamide D-riboside(in) = beta-nicotinamide D-riboside(out)


name: RHOB GAPs stimulate RHOB GTPase activity (Sus scrofa)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Schizosaccharomyces pombe)


name: Ubiquitination of stimulated EGFR (CBL) (Sus scrofa)


name: Phosphorylation of PKC-theta (Rattus norvegicus)


name: PI(3,5)P2 transports from the early endosome membrane to the Golgi membrane (Homo sapiens)


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Saccharomyces cerevisiae)


name: a fatty acyl-CoA + H2O <=> a fatty acid + CoA + H(+)


name: IMPAD1 hydrolyses PAP to AMP (Bos taurus)


name: Activated TrkA receptor internalizes to endosomes (Mus musculus)


name: C30 botryococcene + S-adenosyl-L-methionine <=> 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: an acyl-CoA + cholesterol <=> a cholesterol ester + CoA


name: SARS-CoV-2 N binds to TRIM25 (Homo sapiens)


name: AH2 + cannabichromenate => A + cannabinerolate


name: 4-(trimethylamino)butanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> crotonobetainyl-CoA + reduced [electron-transfer flavoprotein]


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1b (d18:1(4E)) + CMP + H(+)


name: p-PKR dimer phosphorylates SNCA (Rattus norvegicus)


name: beta-D-GalNAc-(1->4)-alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + H2O = alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + N-acetyl-D-galactosamine


name: Degradation of ubiquitinated beta catenin by the proteasome (Mus musculus)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Rattus norvegicus)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Homo sapiens)


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Mus musculus)


name: aclacinomycin S + dTDP-2-deoxy-beta-L-fucose <=> 2-deoxy-alpha-L-fucosylaclacinomycin S + dTDP + H(+)


name: 2-oxoglutarate + an alkane-alpha,omega-diamine = an omega-aminoaldehyde + L-glutamate


name: 2 (2S)-bisdechlorogeodin + 2 H2O => 2 H(+) + O2 + 2 sulochrin


name: DRD2 antagonist drugs bind to DRD2 (Bos taurus)


name: H(+) + malonate + urea => 3-oxo-3-ureidopropanoate + H2O


name: LC3 is cleaved by ATG4 (Plasmodium falciparum)


name: RAC1 and CDC42 activate PAK3 (Xenopus tropicalis)


name: L-tryptophan + O2 => N-formyl-L-kynurenine


name: Loading of PCNA - Sliding Clamp Formation (Drosophila melanogaster)


name: 2-deoxy-D-glucose 6-phosphate + NADP(+) => 2-deoxy-6-phospho-D-glucono-1,5-lactone + H(+) + NADPH


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O


name: Phosphorylated STAT5 is released (Mus musculus)


name: Interaction of IQGAP1 with nephrin (Homo sapiens)


name: p-T774-PKN1 phosphorylates CDC25C (Canis familiaris)


name: phosphogluconate dehydrogenase (decarboxylating) activity


name: 1-acyl LPI is acylated to PI by MBOAT7 (Schizosaccharomyces pombe)


name: a (1S,10aS)-3-(CONH2)-1-(Me2N)-3,3a,4,6-(HO)4-2,5-dioxo-1H,10aH,11H,11aH-cyclopenta[b]anthracene + CO + H2O + NADP(+) => a tetracycline + H(+) + NADPH + O2


name: D-tryptophan + malonyl-CoA => CoA + H(+) + N(2)-malonyl-D-tryptophan


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose <=> a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + H(+) + UDP


name: 4-hydroxy-6-methylpretetramide + NADPH + O2 = 4-dedimethylamino-4-oxo-anhydrotetracycline + H2O + NADP(+)


name: (S)-bulbocapnine + S-adenosyl-L-methionine <=> (S)-N-methylbulbocapnine + H(+) + S-adenosyl-L-homocysteine


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: The anterograde IFT train dissociates (Canis familiaris)


name: (22E)-3-oxochola-4,22-dien-24-oyl-CoA + H2O = (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA


name: H2O + N,N'-diacetylchitobiono-1,5-lactone <=> H(+) + N,N'-diacetylchitobionate


name: alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate => alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid IIA => a 2-acyl-sn-glycero-3-phosphocholine + a lipid IIB


name: glycyl-L-asparagine + H2O => glycine + L-asparagine


name: TNFRSF6B binds TNFSF6,14,15 (Homo sapiens)


name: G alpha (s) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Drosophila melanogaster)


name: a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase


name: Active ALK phosphorylates SHC1 (Gallus gallus)


name: aliphatic (S)-hydroxynitrile lyase activity


name: (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z,15Z)-hexadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Bos taurus)


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Drosophila melanogaster)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS (Homo sapiens)


name: acetyl-CoA + hexan-1-ol => CoA + hexyl acetate


name: 12-hexadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + H(+) + hexadecanoate


name: REV1-Pol kappa complex formation (Gallus gallus)


name: 5' overhang single-stranded DNA endodeoxyribonuclease activity


name: PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Gallus gallus)


name: (3S)-citramalate + succinyl-CoA = (3S)-citramalyl-CoA + succinate


name: Molybdenum ion transfer onto molybdopterin (Mus musculus)


name: lactose(out) + N(pros)-phospho-L-histidyl-[protein] = L-histidyl-[protein] + lactose 6-phosphate(in)


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: PRMT1 arginine-methylates RUNX1 (Rattus norvegicus)


name: a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP


name: NEU4 hydrolyses Neu5Ac from glycoconjugates (Rattus norvegicus)


name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) (Bos taurus)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Bos taurus)


name: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) = 3,7-dideoxy-D-threo-hepto-2,6-diuolosonate + H(+) + NADH + NH4(+)


name: adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: Binding of cAMP to HCN channels (Sus scrofa)


name: Activated FGFR1 phosphorylates PLCG1 (Sus scrofa)


name: KDM1A is recruited to MYC and BCL2 genes (Schizosaccharomyces pombe)


name: galactitol 1-phosphate + NAD(+) <=> H(+) + keto-D-tagatose 6-phosphate + NADH


name: a medium chain fatty acid + ATP + holo-[ACP] <=> a medium-chain fatty acyl-[ACP] + AMP + diphosphate


name: STUB1 polyubiquitinates RUNX2 (Sus scrofa)


name: H2O + octanedioyl-CoA = CoA + H(+) + octanedioate


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Drosophila melanogaster)


name: NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Gallus gallus)


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Homo sapiens)


name: a globoside GalGb4Cer (d18:1(4E)) + GDP-beta-L-fucose = a globoside Globo-H (d18:1(4E)) + GDP + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate + 3 isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + 3 diphosphate


name: 1-hexadecanoyl-sn-glycero-3-phosphate + NADP(+) <=> 1-hexadecanoylglycerone 3-phosphate + H(+) + NADPH


name: Mutant MRAS:SHOC2:PPP1CC complexes dephosphorylate inactive RAFs (Homo sapiens)


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Sus scrofa)


name: Recruitment of DNA2 endonuclease to the C strand (Homo sapiens)


name: SGTA binds Tail-anchored protein (Homo sapiens)


name: 4-hydroxybenzoate + 2 H(+) + NADPH + O2 => CO2 + H2O + hydroquinone + NADP(+)


name: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Homo sapiens)


name: Acireductone is oxidized to MOB (Mus musculus)


name: 2 A + all-trans-zeta-carotene <=> 2 AH2 + all-trans-lycopene


name: Tyrosine is hydroxylated to dopa (Rattus norvegicus)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Rattus norvegicus)


name: dTDP-beta-L-evernosamine + H(+) + 2 NADPH + 2 O2 => dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 3 H2O + 2 NADP(+)


name: prostaglandin G2 = (15S)-15-hydroperoxy-prostaglandin E2


name: RISC binds inexactly matching target RNAs (Homo sapiens)


name: The 60S subunit joins the translation initiation complex  (Caenorhabditis elegans)


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Mus musculus)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Drosophila melanogaster)


name: Interaction of DAP12 and CLM7 (Rattus norvegicus)


name: (R)-carnitine + octadecanoyl-CoA = CoA + O-octadecanoyl-(R)-carnitine


name: M2-1 localizes to nucleus (Homo sapiens)


name: NEIL1 translocates to the nucleus (Mus musculus)


name: (E,E)-piperlonguminine + CoA + H(+) => (E,E)-piperoyl-CoA + 2-methylpropan-1-amine


name: miR-19a microRNA binds CNOT6L mRNA (Homo sapiens)


name: Gastrin binds to CCK-B receptor (Rattus norvegicus)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Drosophila melanogaster)


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Rattus norvegicus)


name: Association of profilin with monomeric actin (Canis familiaris)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Sus scrofa)


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Rattus norvegicus)


name: 2 H2O + NADP(+) + orlandin => 2 7-demethylsiderin + NADPH + O2


name: Growth hormone receptor binds JAK2 (Gallus gallus)


name: SUMOylation of RXRA with SUMO1 (Xenopus tropicalis)


name: 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Plasmodium falciparum)


name: RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Dictyostelium discoideum)


name: P2Y2 receptor binds ATP and UTP (Homo sapiens)


name: an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + H2O <=> 1D-myo-inositol 1-phosphate + an N-acyl-(4R)-4-hydroxysphinganine + H(+)


name: transmembrane receptor protein serine/threonine kinase activity


name: ATP + L-seryl-[Fas-activated protein] <=> ADP + H(+) + O-phospho-L-seryl-[Fas-activated protein]


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Homo sapiens)


name: a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O


name: Casein kinase II phosphorylates STARD10 (Mus musculus)


name: p-S318,221-HuR binds mRNA (Xenopus tropicalis)


name: LTA trimer binds TNFRSF1A,1B,14 (Danio rerio)


name: USP2 deubiquitinates MDM2,MDM4 (Homo sapiens)


name: 3-methoxybenzaldehyde + AMP + diphosphate + NADP(+) => 3-methoxybenzoate + ATP + H(+) + NADPH


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Homo sapiens)


name: PAN2-PAN3 complex partially deadenylates mRNA (Mus musculus)


name: FMNH2 + N-acetyl-S-benzyl-L-cysteine + O2 = (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: ATP + isopentenyl phosphate <=> ADP + isopentenyl diphosphate


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Bos taurus)


name: RAC1 binds effectors at the plasma membrane (Rattus norvegicus)


name: acetyl-CoA + L-methionine = CoA + H(+) + N(alpha)-acetyl-L-methionine


name: factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) (Homo sapiens)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Drosophila melanogaster)


name: ProGIP translocates from the ER Lumen to secretory granules (Xenopus tropicalis)


name: PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA (Canis familiaris)


name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Xenopus tropicalis)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP-alpha-D-mannose => (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + GDP + H(+)


name: alpha-D-glucose 1-phosphate + O-phospho-L-seryl-[protein] <=> alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Dictyostelium discoideum)


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Homo sapiens)


name: Phosphorylation of pPTK2 by SRC (Mus musculus)


name: ent-kaur-16-en-19-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => ent-kaur-16-ene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Bos taurus)


name: P2X1-mediated entry of Ca++ from plasma (Dictyostelium discoideum)


name: acetaldehyde + trimethylamine => choline


name: (5S,6S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O => (5S)-hydroperoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate


name: TP53 binds the BIRC5 gene (Homo sapiens)


name: (4R)-hydroxysphinganine 1-phosphate + H2O => (4R)-hydroxysphinganine + phosphate


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Bos taurus)


name: SMG6 hydrolyzes mRNA with premature termination codon (Mus musculus)


name: H(+) + N-ethylmaleimide + NADH => N-ethylsuccinimide + NAD(+)


name: Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc (Homo sapiens)


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 = 13-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: Phosphorylation and activation of Ezrin (Rattus norvegicus)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) (Gallus gallus)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Sus scrofa)


name: H(+) + N(2)-(ADP-D-ribosyl)-3',5'-cyclic GMP + nicotinamide => 3',5'-cyclic GMP + NAD(+)


name: a gentamycin + GTP => a gentamycin 2''-phosphate + GDP + H(+)


name: SEC24A,B:SEC23A bind SEC22B (Mus musculus)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Bos taurus)


name: NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Mus musculus)


name: 5,6-dihydrothymine + NAD(+) = H(+) + NADH + thymine


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Sus scrofa)


name: H2O + N(omega),N(omega)-dimethyl-L-arginine => dimethylamine + L-citrulline


name: NF-kB migrates to the nucleus and turns on transcription (Sus scrofa)


name: p62 binds ubiquitinated mitochondrial substrates (Mus musculus)


name: 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: L-ornithine(out) + putrescine(in) <=> L-ornithine(in) + putrescine(out)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + formaldehyde


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Saccharomyces cerevisiae)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Bos taurus)


name: Proteinase-activated receptors can bind thrombin (Xenopus tropicalis)


name: Exocytosis of Proactivator polypeptide (Mus musculus)


name: (E,E)-piperoyl-CoA + pyrrolidine => CoA + H(+) + piperyline


name: ITPA hydrolyses ITP to IMP (Homo sapiens)


name: acetyl-CoA + an S-substituted L-cysteine => an N-acetyl-L-cysteine-S-conjugate + CoA + H(+)


name: ATP + CoA + pentadecanoate <=> AMP + diphosphate + pentadecanoyl-CoA


name: H2O + N-(hexanoyl)sphing-4-enine = hexanoate + sphing-4-enine


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Xenopus tropicalis)


name: guanosine(10) in tRNA + 2 S-adenosyl-L-methionine => 2 H(+) + N(2)-dimethylguanosine(10) in tRNA + 2 S-adenosyl-L-homocysteine


name: (4R)-hydroxysphinganine 1-phosphate + ADP + H(+) => (4R)-hydroxysphinganine + ATP


name: H2O + N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] => (S)-4,5-dihydroxy-2-oxopentanal + L-lysyl-[protein] + phosphate


name: (E)-4-coumaroyl-CoA + H(+) + NADPH => (E)-4-coumaraldehyde + CoA + NADP(+)


name: PP2A dephosphorylates KSR1 (Mus musculus)


name: RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc (Rattus norvegicus)


name: ADP(out) + FMN(in) => ADP(in) + FMN(out)


name: uridine(516) in 16S rRNA <=> pseudouridine(516) in 16S rRNA


name: 3beta-hydroxy-lanosta-8, 24-dien-26-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 26-oxolanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Canis familiaris)


name: formate + L-aspartate => H2O + N-formyl-L-aspartate


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Canis familiaris)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Mus musculus)


name: NH4(+) + S-inosyl-L-homocysteine => H(+) + H2O + S-adenosyl-L-homocysteine


name: Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Bos taurus)


name: cholesterol + H(+) + NADPH + O2 => 7-dehydrocholesterol + 2 H2O + NADP(+)


name: (2E)-5-methylhexenoyl-[ACP] + H(+) + NADH <=> 5-methylhexanoyl-[ACP] + NAD(+)


name: TP53BP1 recruits DCLRE1C to ATM (Canis familiaris)


name: SLCO4C1 mediates the transport of digoxin (Mus musculus)


name: Association of Cks1 with SCF(Skp2) complex (Gallus gallus)


name: H2O + octadecanamide <=> NH4(+) + octadecanoate


name: ROS oxidize thioredoxin and activate MAP3K5 (Saccharomyces cerevisiae)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Mus musculus)


name: mycophenolate + UDP-alpha-D-glucuronate <=> H(+) + mycophenolate 7-O-beta-D-glucuronide + UDP


name: PDE4A hydrolyses cAMP to AMP (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a carboxylate + ergosterol + H(+) => ergosteryl ester + H2O


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Rattus norvegicus)


name: LDH tetramer oxidises LACT to PYR (Mus musculus)


name: ATP + phosphate + pyruvate => AMP + diphosphate + H(+) + phosphoenolpyruvate


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Canis familiaris)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Homo sapiens)


name: RAC1 GEFs activate RAC1 (Caenorhabditis elegans)


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Canis familiaris)


name: N,N',N''-triacetylchitotriose + O2 = H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone


name: PDPK1 phosphorylates SGK1 (Canis familiaris)


name: 2 H(+) + NADH + phosphonoacetate => H2O + NAD(+) + phosphonoacetaldehyde


name: GBF1 stimulates nucleotide exchange on ARF (Bos taurus)


name: STEAP3-like proteins reduce Fe3+ to Fe2+ (Bos taurus)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Canis familiaris)


name: H2O + NAD(+) + nitrite = H(+) + NADH + nitrate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (-)-trans-permethrin + H2O <=> (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + (3-phenoxyphenyl)methanol + H(+)


name: Caspase-mediated cleavage of FADK 1 (Mus musculus)


name: PMM1,2 isomerise Man6P to Man1P (Plasmodium falciparum)


name: 18-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase]


name: L-asparagine(out) + L-glutamine(in) + Na(+)(out) = L-asparagine(in) + L-glutamine(out) + Na(+)(in)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Dictyostelium discoideum)


name: 3-O-methyl-L-dopa + H(+) + S-adenosyl-L-homocysteine => L-dopa + S-adenosyl-L-methionine


name: DCP1-DCP2 complex decaps mRNA (Plasmodium falciparum)


name: Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid (Homo sapiens)


name: Degradation of ubiquitinated SKI/SKIL (Rattus norvegicus)


name: guanosine(1370) in 16S rRNA + S-adenosyl-L-methionine => 2'-O-methylguanosine(1370) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + L-5-carboxymethylhydantoin = H(+) + N-carbamoyl-L-aspartate


name: 2'-deoxyuridine + phosphate => 2-deoxy-alpha-D-ribose 1-phosphate + uracil


name: PGG2 is reduced to PGH2 by PTGS1 (Bos taurus)


name: STON2 binds SYT proteins (Drosophila melanogaster)


name: MeSeOH is reduced to MeSeH by TXNRD1 (Mus musculus)


name: 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z-octadecenoyl)-glycerol + phosphate => (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O


name: [thioredoxin]-dithiol + NADP(+) => [thioredoxin]-disulfide + H(+) + NADPH


name: 2-trans-(+)-abscisate + UDP-alpha-D-glucose <=> beta-D-glucopyranosyl trans-(+)-abscisate + UDP


name: (S)-1-phenylethanol + AH2 => A + ethylbenzene + H2O


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Bos taurus)


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Rattus norvegicus)


name: H2O + N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine = (9Z,12Z)-octadecadienoate + H(+) + N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine


name: (2E)-geraniol + benzoyl-CoA = (2E)-geranyl benzoate + CoA


name: AP-2 directly binds some endocytic cargo (Bos taurus)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Canis familiaris)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Caenorhabditis elegans)


name: DHODH:FMN oxidises (S)-DHO to orotate (Caenorhabditis elegans)


name: N,N-dihydroxy-L-aspartate => (2S)-2-nitrosobutanedioate + H2O


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Rattus norvegicus)


name: CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Homo sapiens)


name: NAD(+) + xylitol => D-xylulose + H(+) + NADH


name: The retrograde IFT train dissociates (Rattus norvegicus)


name: 32-hydroxylanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => lanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine => [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine


name: FOXP3 in complex with RUNX1 binds the CTLA4 gene promoter (Homo sapiens)


name: WICH phosphorylates H2AFX on Y142 (Bos taurus)


name: L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase]


name: arogenate dehydrogenase [NAD(P)+] activity


name: "glyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (phosphorylating)"


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Caenorhabditis elegans)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Mus musculus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Mus musculus)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Sus scrofa)


name: lathosterol + NADP(+) = 5alpha-cholesta-7,24-dien-3beta-ol + H(+) + NADPH


name: isopentenyl diphosphate = dimethylallyl diphosphate


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Rattus norvegicus)


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Mus musculus)


name: Orexin 1 receptor can bind orexin-A neuropeptide (Rattus norvegicus)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADPH


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: a sn-glycero-3-phosphodiester + H2O => an alcohol + H(+) + sn-glycerol 3-phosphate


name: Nascent N is phosphorylated (Homo sapiens)


name: S-(acetaldehyde)-L-cysteine = (4S)-5,6-dihydro-4H-1,3-thiazine-4-carboxylate + H(+) + H2O


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Rattus norvegicus)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+) => beta-D-fructose 6-phosphate + GDP-alpha-D-mannose


name: GPIb-IX-V binds to vWF:Collagen complex (Homo sapiens)


name: SCF-beta-TrCP ubiquitinylates IkB (Xenopus tropicalis)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1) => beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 H(+) + 8 NADH => 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NAD(+)


name: CO2 + pyropheophorbide a => C-13(2)-carboxypyropheophorbide a + H(+)


name: dimethylallyl diphosphate + leachianone G => diphosphate + sophoraflavanone G


name: 9H-carbazole + H(+) + NADH + O2 = 2'-aminobiphenyl-2,3-diol + NAD(+)


name: Fe(2+)(out) + H(+) + monodehydro-L-ascorbate radical(in) => Fe(3+)(out) + L-ascorbate(in)


name: Mitochondrial recruitment of Drp1 (Homo sapiens)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Gallus gallus)


name: formyl-CoA + succinate <=> formate + succinyl-CoA


name: SLCO4C1 mediates the transport of digoxin (Xenopus tropicalis)


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Danio rerio)


name: Translocation of ERBB4s80 to the nucleus (Canis familiaris)


name: 1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)


name: 1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH4(+)


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Drosophila melanogaster)


name: 14-3-3 zeta binding allows recruitment of PI3K (Mus musculus)


name: ATP + kanosamine <=> ADP + D-kanosamine 6-phosphate + H(+)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Canis familiaris)


name: lathosterol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha,8alpha-epoxy-5alpha-cholestan-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MCM4, MCM6 and MCM7 form a heterotrimer (Schizosaccharomyces pombe)


name: (3R)-hydroxybutanoate pentamer + [(3R)-hydroxybutanoate](n-5) + H(+) => [(3R)-hydroxybutanoate](n) + H2O


name: Rheb in the MTORC1 complex hydrolyses GTP (Xenopus tropicalis)


name: (2R,3S)-2,4',7-trihydroxyisoflavanone => daidzein + H(+) + H2O


name: Transactivation of PMAIP1 (NOXA) by E2F1 (Homo sapiens)


name: ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 (Bos taurus)


name: (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA <=> (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O


name: 6-chloropyridine-2,3,5-triol + FADH2 + O2 <=> 3,6-dihydroxypyridine-2,5-dione + chloride + FAD + 3 H(+) + H2O


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Drosophila melanogaster)


name: Association of Ku heterodimer with ends of DNA double-strand breaks (Gallus gallus)


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + di-(9Z)-octadecenoylglycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol


name: HDHD1:Mg2+ dephosphorylates PURIDP (Saccharomyces cerevisiae)


name: (R)-4-dehydropantoate + H2O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH


name: ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG (Canis familiaris)


name: Dimethyl fumarate modifies Cys191 in GSDMD (Mus musculus)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine <=> 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP


name: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)


name: USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Canis familiaris)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Drosophila melanogaster)


name: PP2A methylation by LCMT1 (Rattus norvegicus)


name: Hv1 Mediated H+ Permeability (Canis familiaris)


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Mus musculus)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Sus scrofa)